TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24464788 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23044035 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 17194889 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 11200923 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24056820 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 24056820 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 16923435 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16923435 — Surrogate Endpoint (SUR): Blood pressure
Study 11212063 — Surrogate Endpoint (SUR): Blood pressure
Study 1643912 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 30144554 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 15963082 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12908901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12908901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20639717 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20639717 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15134615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7807504 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8884561 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27197192 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27197192 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27197192 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 27197192 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22828532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17908614 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 16231620 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26609167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25432688 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 16036193 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 12360599 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 31438986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28177691 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17517066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1343613 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1343613 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31144304 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 31144304 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 28794207 — Surrogate Endpoint (SUR): Blood pressure
Study 20359087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16529860 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16529860 — Surrogate Endpoint (SUR): Blood pressure
Study 2859185 — Surrogate Endpoint (SUR): Blood pressure
Study 24717369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24717369 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 18279985 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8436152 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29908319 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28370958 — Surrogate Endpoint (SUR): Blood pressure
Study 28370958 — Surrogate Endpoint (SUR): Serum creatinine
Study 28370958 — Surrogate Endpoint (SUR): Serum calcium
Study 26590810 — Surrogate Endpoint (SUR): Bone mineral density
Study 18509873 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 11194981 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 1464897 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29902286 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 29902286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 26654625 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 21042881 — Surrogate Endpoint (SUR): Blood pressure
Study 1290431 — Surrogate Endpoint (SUR): Blood pressure
Study 24429164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15555502 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 11425971 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 16644856 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 9316325 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25248446 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 17568412 — Safety Biomarker (SAF): DRD2
Study 11916358 — Surrogate Endpoint (SUR): Blood pressure
Study 31647614 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16611272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1507822 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 1507822 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 6742082 — Surrogate Endpoint (SUR): Blood pressure
Study 24307559 — Predictive Biomarker (PRD): ADCY10 mRNA
Genes: ADCY10; SAC
Study 22930049 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 9498441 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21300930 — Predictive Biomarker (PRD): Hormone receptor
Study 12913194 — Surrogate Endpoint (SUR): Bone mineral density
Study 8461269 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 28796885 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 26903255 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17302253 — Monitoring Biomarker (MOI): HBV DNA
Study 14502840 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22096031 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 22096031 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18815445 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 26771522 — Surrogate Endpoint (SUR): Blood pressure
Study 22785114 — Surrogate Endpoint (SUR): Total kidney volume
Study 29989171 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 19382890 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9669786 — Surrogate Endpoint (SUR): Blood pressure
Study 9669786 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9669786 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7915090 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18505169 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18505169 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16783561 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16783561 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 14666027 — Safety Biomarker (SAF): Reactive oxygen species
Study 29869556 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 29869556 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29869556 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study 29869556 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 18792100 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 6148005 — Surrogate Endpoint (SUR): Blood pressure
Study 10382080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10382080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18412989 — Surrogate Endpoint (SUR): Bone mineral density
Study 11187414 — Surrogate Endpoint (SUR): Blood pressure
Study 9536540 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11837758 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 31481504 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21950653 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 10651170 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7666090 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26041862 — Predictive Biomarker (PRD): CHKA mRNA
Genes: CHKA; CHK; CKI
Study 10029243 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19387398 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19387398 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19387398 — Surrogate Endpoint (SUR): Blood pressure
Study 7835116 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 21496064 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 21496064 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30703190 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25482300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17408310 — Safety Biomarker (SAF): KCNH2
Genes: Kv11.1; HERG; erg1
Study 15012622 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 11710890 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 11710890 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 11710890 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7949808 — Surrogate Endpoint (SUR): Blood pressure
Study 28950757 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24562444 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24562444 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24562444 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 17114205 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 14574343 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22232535 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20576462 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 20576462 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 20576462 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study 31246976 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8768057 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24789859 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 24789859 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 22252020 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 1685667 — Surrogate Endpoint (SUR): Blood pressure
Study 7913731 — Surrogate Endpoint (SUR): Serum creatinine
Study 7913731 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31190322 — Surrogate Endpoint (SUR): Blood pressure
Study 27322592 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23040783 — Monitoring Biomarker (MOI): Procalcitonin
Study 23040783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7541190 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7541190 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18591167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23622019 — Predictive Biomarker (PRD): HBE1 mRNA
Genes: HBE1; HBE
Study 20589679 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 19526158 — Surrogate Endpoint (SUR): Blood pressure
Study 17502045 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23633524 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 1488663 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 29878043 — Surrogate Endpoint (SUR): Blood pressure
Study 27281699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15879361 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12569213 — Surrogate Endpoint (SUR): Blood pressure
Study 8634167 — Surrogate Endpoint (SUR): Blood pressure
Study 30922327 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study 19951570 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19951570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19951570 — Surrogate Endpoint (SUR): Blood pressure
Study 30593882 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 26849270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21920532 — Surrogate Endpoint (SUR): Blood pressure
Study 17254923 — Surrogate Endpoint (SUR): Blood pressure
Study 7737228 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23271901 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 19827649 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19827649 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 19827649 — Surrogate Endpoint (SUR): Blood pressure
Study 26843390 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 24595630 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 19514558 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 31995812 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 29047145 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21078806 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 21078806 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 15806416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15806416 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 15806416 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 15806416 — Safety Biomarker (SAF): Interleukin 1
Study 15806416 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 17391168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8571077 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16822110 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 11948003 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 26149189 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26149189 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21659360 — Predictive Biomarker (PRD): ACOX3 mRNA
Genes: ACOX3; BRCOX; PRCOX
Study 21659360 — Predictive Biomarker (PRD): CENPF mRNA
Genes: CENPF
Study 21659360 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 21659360 — Predictive Biomarker (PRD): IL22RA2 mRNA
Genes: IL22RA2; UNQ5793/PRO19598/PRO19822
Study 18022303 — Predictive Biomarker (PRD): SIGLEC1 mRNA
Genes: SIGLEC1; SN
Study 12013322 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20806988 — Surrogate Endpoint (SUR): Blood pressure
Study 17851996 — Safety Biomarker (SAF): PPOX
Genes: HCRT; OX
Study 2180271 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 2180271 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 453982 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20962614 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1642023 — Surrogate Endpoint (SUR): Blood pressure
Study 6403965 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 23526980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11113401 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3297472 — Surrogate Endpoint (SUR): Blood pressure
Study 3297472 — Surrogate Endpoint (SUR): Serum potassium
Study 29211295 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 27350298 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 27350298 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27350298 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25006069 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23880340 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 20577753 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 17664372 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 665565 — Surrogate Endpoint (SUR): Blood pressure
Study 31455295 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25940230 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 25940230 — Predictive Biomarker (PRD): APOA2 mRNA
Genes: APOA2
Study 25940230 — Predictive Biomarker (PRD): MLXIPL mRNA
Genes: MLXIPL; BHLHD14; MIO; WBSCR14
Study 25940230 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 25940230 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 25940230 — Predictive Biomarker (PRD): GCKR mRNA
Genes: GCKR
Study 25940230 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7522283 — Surrogate Endpoint (SUR): Blood pressure
Study 2891533 — Surrogate Endpoint (SUR): Blood pressure
Study 12830458 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 12830458 — Surrogate Endpoint (SUR): Serum creatinine
Study 10390406 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 30856025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21737561 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31062731 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 18212314 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10642232 — Surrogate Endpoint (SUR): Blood pressure
Study 7506580 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7506580 — Safety Biomarker (SAF): Interleukin 1
Study 7506580 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7506580 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31925317 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 31925317 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 23953523 — Surrogate Endpoint (SUR): Serum creatinine
Study 8258676 — Surrogate Endpoint (SUR): Blood pressure
Study 30675708 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 18833861 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28497265 — Safety Biomarker (SAF): Cytoplasmic malate dehydrogenase
Genes: MDH1; MDHA
Study 30623568 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 24300544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24300544 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19710187 — Predictive Biomarker (PRD): EBF3 mRNA
Genes: EBF3; COE3
Study 19710187 — Surrogate Endpoint (SUR): Blood pressure
Study 10586916 — Predictive Biomarker (PRD): MTM1 mRNA
Genes: MTM1; CG2
Study 28604824 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27206951 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17268695 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15470329 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26624824 — Surrogate Endpoint (SUR): Blood pressure
Study 12700622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12700622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12700622 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12700622 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 20152050 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 18230015 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 23116213 — Surrogate Endpoint (SUR): Blood pressure
Study 335093 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27427555 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 26011919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16624773 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11411461 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9236426 — Surrogate Endpoint (SUR): Blood pressure
Study 2890525 — Surrogate Endpoint (SUR): Blood pressure
Study 20447934 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20447934 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 20447934 — Surrogate Endpoint (SUR): Blood pressure
Study 18166815 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18166815 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14632754 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14632754 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 8721025 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 19434815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15447921 — Surrogate Endpoint (SUR): Bone mineral density
Study 17429083 — Safety Biomarker (SAF): Interleukin 1
Study 17429083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17429083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26288120 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS