TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28655715 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28655715 — Predictive Biomarker (PRD): CBR1 mRNA
Genes: CBR1; CBR; CRN; SDR21C1
Study 14693576 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11836046 — Surrogate Endpoint (SUR): Bone mineral density
Study 11836046 — Surrogate Endpoint (SUR): Urinary oxalate
Study 17047639 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2157450 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 393519 — Surrogate Endpoint (SUR): Blood pressure
Study 23147173 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16108933 — Surrogate Endpoint (SUR): Blood pressure
Study 31985471 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 29720440 — Surrogate Endpoint (SUR): Blood pressure
Study 1541981 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26137537 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26137537 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26137537 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 26137537 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23198737 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9781939 — Surrogate Endpoint (SUR): Blood pressure
Study 7942731 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 7942731 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 25469044 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 25469044 — Predictive Biomarker (PRD): BOC mRNA
Genes: BOC; UNQ604/PRO1190
Study 23122795 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23122795 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 18599165 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15850494 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11802206 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 11802206 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 11802206 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26258842 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 26258842 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 20842417 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11457465 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 7870008 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 25275341 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20667838 — Surrogate Endpoint (SUR): Blood pressure
Study 26312582 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11104393 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 11104393 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 8445231 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 8445231 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8445231 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 27139431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24481415 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17343310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31814312 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26978418 — Safety Biomarker (SAF): Hyaluronic acid
Study 12208595 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12208595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19242322 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9696260 — Surrogate Endpoint (SUR): Probing pocket depth
Study 2759945 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16243460 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study 8898770 — Surrogate Endpoint (SUR): Blood pressure
Study 6371575 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 30821053 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30821053 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17241150 — Surrogate Endpoint (SUR): Blood pressure
Study 15741434 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27215836 — Surrogate Endpoint (SUR): Blood pressure
Study 22718840 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 22718840 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 18277064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18277064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15711829 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19384186 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 12812865 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 8815751 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31741126 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 28454014 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 25754396 — Surrogate Endpoint (SUR): Blood pressure
Study 23150126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23150126 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9786807 — Surrogate Endpoint (SUR): Blood pressure
Study 31182183 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 31182183 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 23945072 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 15976213 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15976213 — Surrogate Endpoint (SUR): Blood pressure
Study 12598346 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 2137888 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29784890 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 7573783 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 25456867 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 25456867 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8880078 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 1824707 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 6851041 — Surrogate Endpoint (SUR): Blood pressure
Study 23288870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22024001 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 22024001 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 16922703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16922703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16922703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16922703 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 16922703 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 3174151 — Surrogate Endpoint (SUR): Blood pressure
Study 11790211 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 10430735 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31140297 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24991733 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 24991733 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17391164 — Surrogate Endpoint (SUR): Blood pressure
Study 7749424 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31076261 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31076261 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31076261 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20055751 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10082498 — Surrogate Endpoint (SUR): Blood pressure
Study 2405555 — Surrogate Endpoint (SUR): Serum creatinine
Study 29781483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26707220 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26707220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18783876 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 11668312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31010703 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22285946 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 12736474 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8653836 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 8653836 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8653836 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 3327445 — Surrogate Endpoint (SUR): Blood pressure
Study 31948661 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 1826912 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 6628498 — Surrogate Endpoint (SUR): Blood pressure
Study 23299853 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 21174007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7905101 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31490025 — Predictive Biomarker (PRD): ELANE mRNA
Genes: ELANE; ELA2
Study 31490025 — Predictive Biomarker (PRD): PRTN3 mRNA
Genes: PRTN3; MBN
Study 12560299 — Surrogate Endpoint (SUR): Blood pressure
Study 10716371 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8231034 — Surrogate Endpoint (SUR): Blood pressure
Study 3544940 — Surrogate Endpoint (SUR): Blood pressure
Study 26829083 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 20354032 — Surrogate Endpoint (SUR): Serum creatinine
Study 25693055 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 15513324 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 3142242 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3142242 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19758358 — Surrogate Endpoint (SUR): Blood pressure
Study 1860763 — Surrogate Endpoint (SUR): Serum creatinine
Study 29985202 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26905703 — Surrogate Endpoint (SUR): Blood pressure
Study 16533865 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16533865 — Surrogate Endpoint (SUR): Blood pressure
Study 1410729 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 20404622 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 10513830 — Surrogate Endpoint (SUR): Blood pressure
Study 6181329 — Surrogate Endpoint (SUR): Blood pressure
Study 31670790 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 30623408 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 27464957 — Surrogate Endpoint (SUR): Blood pressure
Study 22535635 — Surrogate Endpoint (SUR): Blood pressure
Study 15072869 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 22867630 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22867630 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12057066 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8605053 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30816640 — Surrogate Endpoint (SUR): Bone mineral density
Study 11908511 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10452629 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2218650 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29493059 — Surrogate Endpoint (SUR): Serum creatinine
Study 29493059 — Surrogate Endpoint (SUR): Serum sodium
Study 22127230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FBXO32 mRNA
Genes: FBXO32
Study 15954913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15954913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10636510 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27586249 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30646102 — Surrogate Endpoint (SUR): Blood pressure
Study 30646102 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26554661 — Surrogate Endpoint (SUR): Serum testosterone
Study 23443441 — Surrogate Endpoint (SUR): Serum potassium
Study 21595575 — Safety Biomarker (SAF): IL-6 and IL-10
Study 27809637 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27809637 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19578239 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19578239 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27251407 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 25549482 — Surrogate Endpoint (SUR): Blood pressure
Study 18092565 — Surrogate Endpoint (SUR): Blood pressure
Study 10517046 — Safety Biomarker (SAF): BDNF
Study 25167350 — Surrogate Endpoint (SUR): Bone mineral density
Study 9883544 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28156007 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21707911 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 28867335 — Surrogate Endpoint (SUR): Blood pressure
Study 14980069 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29339032 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9623511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3335825 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26419527 — Surrogate Endpoint (SUR): Blood pressure
Study 22405570 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 7539625 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 7539625 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 7539625 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 7539625 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 28263812 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21584847 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20876669 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11374113 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15278585 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15278585 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 15278585 — Surrogate Endpoint (SUR): Blood pressure
Study 15048062 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28808723 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 11401935 — Safety Biomarker (SAF): Reactive oxygen species
Study 8214647 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2871915 — Surrogate Endpoint (SUR): Blood pressure
Study 28669606 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22334806 — Surrogate Endpoint (SUR): Blood pressure
Study 12694138 — Surrogate Endpoint (SUR): Blood pressure
Study 31590426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17580443 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17580443 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 11523414 — Surrogate Endpoint (SUR): Blood pressure
Study 14584388 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11068313 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30654471 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27853876 — Surrogate Endpoint (SUR): Blood pressure
Study 26427960 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 23091101 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 26661467 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 12090977 — Predictive Biomarker (PRD): Hormone receptor
Study 19378223 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1930923 — Surrogate Endpoint (SUR): Blood pressure
Study 22022222 — Surrogate Endpoint (SUR): Blood pressure
Study 15661835 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12107601 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31240513 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 19018805 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19018805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19018805 — Safety Biomarker (SAF): BDNF
Study 17846333 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17846333 — Surrogate Endpoint (SUR): Serum creatinine
Study 15565603 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 7874374 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 25594611 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 24391768 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8664843 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6527524 — Surrogate Endpoint (SUR): Blood pressure
Study 6527524 — Surrogate Endpoint (SUR): Serum uric acid
Study 26608718 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26608718 — Safety Biomarker (SAF): BDNF
Study 17617944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17617944 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7995001 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9792489 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25491384 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 8948688 — Surrogate Endpoint (SUR): Blood pressure
Study 30934797 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29556618 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 17145253 — Surrogate Endpoint (SUR): Blood pressure
Study 8905472 — Surrogate Endpoint (SUR): Blood pressure
Study 1713132 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21401764 — Surrogate Endpoint (SUR): Blood pressure
Study 18416823 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18416823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18416823 — Surrogate Endpoint (SUR): Blood pressure
Study 9487836 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 24886787 — Surrogate Endpoint (SUR): Serum creatinine
Study 21798891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16161944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8641404 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8641404 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 1729865 — Surrogate Endpoint (SUR): Blood pressure
Study 25201893 — Surrogate Endpoint (SUR): Blood pressure
Study 11916912 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 7654506 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2199642 — Surrogate Endpoint (SUR): Blood pressure
Study 27569177 — Surrogate Endpoint (SUR): Blood pressure
Study 18036362 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 15606434 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15606434 — Surrogate Endpoint (SUR): Blood pressure
Study 12030732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 6786069 — Surrogate Endpoint (SUR): Blood pressure
Study 20530614 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 8845083 — Surrogate Endpoint (SUR): Blood pressure
Study 8845083 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2015177 — Surrogate Endpoint (SUR): Blood pressure
Study 27571713 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27571713 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22884611 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 2474057 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 23286834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1505537 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28847205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28847205 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10586205 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31639321 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 16963041 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9417802 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27048405 — Monitoring Biomarker (MOI): Procalcitonin
Study 27048405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1