TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8872973 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10193874 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 30871514 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30871514 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30871514 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28986058 — Surrogate Endpoint (SUR): Blood pressure
Study 26404640 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 23084675 — Predictive Biomarker (PRD): ISM1 mRNA
Genes: ISM1; C20orf82; ISM
Study 19934131 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2172280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2172280 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31858673 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30741744 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30741744 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30741744 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26864362 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 26864362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 30169657 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 30169657 — Surrogate Endpoint (SUR): Blood pressure
Study 24282872 — Surrogate Endpoint (SUR): Bacterial count
Study 26632893 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8983091 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 24598244 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 20564242 — Surrogate Endpoint (SUR): Bone mineral density
Study 15129394 — Surrogate Endpoint (SUR): Bone mineral density
Study 27592112 — Predictive Biomarker (PRD): BIRC5 mRNA
Genes: BIRC5; API4; IAP4
Study 27592112 — Predictive Biomarker (PRD): TFF1 mRNA
Genes: TFF1; BCEI; PS2
Study 27592112 — Predictive Biomarker (PRD): MYBL2 mRNA
Genes: MYBL2; BMYB
Study 27592112 — Predictive Biomarker (PRD): CCNB1 mRNA
Genes: CCNB1; CCNB
Study 16297750 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 16297750 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 10816746 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8574280 — Surrogate Endpoint (SUR): Blood pressure
Study 540445 — Surrogate Endpoint (SUR): Blood pressure
Study 29948221 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 29948221 — Predictive Biomarker (PRD): ITPR1 mRNA
Genes: ITPR1; INSP3R1
Study 29948221 — Predictive Biomarker (PRD): MTSS1 mRNA
Genes: MTSS1; KIAA0429; MIM
Study 22829944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22829944 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22829944 — Surrogate Endpoint (SUR): Blood pressure
Study 12499479 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 25467012 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 25467012 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30476490 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27465384 — Surrogate Endpoint (SUR): Blood pressure
Study 27465384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20802250 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 18852398 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18852398 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18852398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12064336 — Surrogate Endpoint (SUR): Bone mineral density
Study 12064336 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 30674601 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 28624898 — Surrogate Endpoint (SUR): Blood pressure
Study 17516022 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 12886697 — Surrogate Endpoint (SUR): Blood pressure
Study 8160096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18245546 — Predictive Biomarker (PRD): CLU mRNA
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 16989201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16989201 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12975739 — Surrogate Endpoint (SUR): Blood pressure
Study 1679961 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 3083741 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 3083741 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3083741 — Surrogate Endpoint (SUR): Blood pressure
Study 29471812 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20942667 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8660020 — Surrogate Endpoint (SUR): Blood pressure
Study 20522572 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 2542682 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26404895 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 17463304 — Predictive Biomarker (PRD): NCAM1 mRNA
Genes: NCAM1; NCAM
Study 2951051 — Surrogate Endpoint (SUR): Blood pressure
Study 23994382 — Monitoring Biomarker (MOI): HBV DNA
Study 22743137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20845002 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 16630151 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10618542 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 19384263 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 12081584 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 12081584 — Surrogate Endpoint (SUR): Serum calcium
Study 3265347 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25764956 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 16299352 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 16299352 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1627419 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16361166 — Surrogate Endpoint (SUR): Blood pressure
Study 10641952 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7772614 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31865631 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30981585 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 28834469 — Surrogate Endpoint (SUR): Blood pressure
Study 25689936 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18794865 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18794865 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15207943 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 19841149 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28109962 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28109962 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28109962 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28109962 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 21528627 — Surrogate Endpoint (SUR): Bone mineral density
Study 16062032 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11783255 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8721897 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2551560 — Surrogate Endpoint (SUR): Blood pressure
Study 2551560 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 31693083 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 30377198 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 30377198 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 19738090 — Monitoring Biomarker (MOI): Procalcitonin
Study 11552664 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 11552664 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2971549 — Surrogate Endpoint (SUR): Blood pressure
Study 24929949 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 24929949 — Predictive Biomarker (PRD): SLC35A2 mRNA
Genes: SLC35A2; UGALT; UGT; UGTL
Study 22292421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22292421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10456490 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31109746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22418908 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22418908 — Surrogate Endpoint (SUR): Blood pressure
Study 22145774 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 11520994 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 29220524 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 17205304 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 9832300 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 2693440 — Surrogate Endpoint (SUR): Serum triglycerides
Study 324487 — Surrogate Endpoint (SUR): Blood pressure
Study 21204963 — Surrogate Endpoint (SUR): Blood pressure
Study 10681072 — Surrogate Endpoint (SUR): Blood pressure
Study 9501335 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 30024627 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21632213 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 8930174 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27491778 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 27491778 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 24445732 — Surrogate Endpoint (SUR): Bone mineral density
Study 18427285 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16751039 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 7578986 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25413567 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 15319567 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7123498 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25921035 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 22480204 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 22480204 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 22480204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24944140 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 24944140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 31369406 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28131632 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28131632 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 28131632 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study 3069752 — Surrogate Endpoint (SUR): Blood pressure
Study 17310818 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30670043 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 8551493 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29017497 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21910074 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 31018614 — Surrogate Endpoint (SUR): Bone mineral density
Study 6621025 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 6621025 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26806045 — Surrogate Endpoint (SUR): Plasma sitosterol and campesterol
Study 16219105 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 7318340 — Surrogate Endpoint (SUR): Blood pressure
Study 15105178 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2642538 — Predictive Biomarker (PRD): TOX mRNA
Genes: TOX; KIAA0808
Study 2642538 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study 31838199 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 25514103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25514103 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 25514103 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21660077 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 9626918 — Surrogate Endpoint (SUR): Blood pressure
Study 29526019 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 22538329 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22538329 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22538329 — Surrogate Endpoint (SUR): Blood pressure
Study 30880285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25806862 — Surrogate Endpoint (SUR): Serum creatinine
Study 17299107 — Surrogate Endpoint (SUR): Blood pressure
Study 29737494 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 29737494 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 29737494 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 29737494 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 29737494 — Predictive Biomarker (PRD): IL6ST mRNA
Genes: IL6ST
Study 29737494 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 29737494 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 29737494 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 29737494 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 29737494 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 29737494 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study 21435141 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 8440094 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 3527514 — Surrogate Endpoint (SUR): Blood pressure
Study 3527514 — Surrogate Endpoint (SUR): Serum potassium
Study 3527514 — Surrogate Endpoint (SUR): Serum uric acid
Study 25502581 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25502581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25502581 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 18268422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1417231 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1417231 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 30429144 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 12501741 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 3131041 — Surrogate Endpoint (SUR): Blood pressure
Study 8784319 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28829934 — Predictive Biomarker (PRD): POU1F1 mRNA
Genes: POU1F1; GHF1; PIT1
Study 28829934 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 25742472 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25742472 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25742472 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 19552227 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 17343309 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 11295651 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 9560064 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9560064 — Surrogate Endpoint (SUR): Blood pressure
Study 30614275 — Surrogate Endpoint (SUR): Blood pressure
Study 9648990 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9648990 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23370069 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 18451314 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9559790 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8582392 — Surrogate Endpoint (SUR): Blood pressure
Study 756039 — Surrogate Endpoint (SUR): Serum sodium
Study 756039 — Surrogate Endpoint (SUR): Blood pressure
Study 30586701 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28457231 — Surrogate Endpoint (SUR): Blood pressure
Study 24971677 — Surrogate Endpoint (SUR): Blood pressure
Study 10326065 — Surrogate Endpoint (SUR): Bone mineral density
Study 1788750 — Surrogate Endpoint (SUR): Blood pressure
Study 6267643 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23974250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9151148 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 23590389 — Monitoring Biomarker (MOI): Procalcitonin
Study 30756167 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 21991740 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21991740 — Surrogate Endpoint (SUR): Blood pressure
Study 18926729 — Safety Biomarker (SAF): Interleukin 1
Study 18926729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10850391 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 27863843 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27863843 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26119263 — Surrogate Endpoint (SUR): Blood pressure
Study 8471592 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 8471592 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8471592 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8471592 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3042354 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3042354 — Surrogate Endpoint (SUR): Blood pressure
Study 29220114 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 25553110 — Monitoring Biomarker (MOI): HBV DNA
Study 21614492 — Predictive Biomarker (PRD): HTR2C mRNA
Genes: HTR2C; HTR1C
Study 21614492 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 21614492 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 21614492 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21614492 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 16584354 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 16584354 — Predictive Biomarker (PRD): MARCKSL1 mRNA
Genes: MARCKSL1; MLP; MRP
Study 20542811 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27734257 — Surrogate Endpoint (SUR): Serum calcium
Study 27734257 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 11235144 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11235144 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2537561 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2248385 — Surrogate Endpoint (SUR): Blood pressure
Study 2248385 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30461542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25982143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25982143 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10063307 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10063307 — Monitoring Biomarker (MOI): HBV DNA
Study 8803516 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8803516 — Surrogate Endpoint (SUR): Blood pressure
Study 8803516 — Surrogate Endpoint (SUR): Serum sodium
Study 8803516 — Surrogate Endpoint (SUR): Serum creatinine
Study 28072888 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 23771840 — Surrogate Endpoint (SUR): Blood pressure
Study 17623958 — Surrogate Endpoint (SUR): Blood pressure
Study 11157376 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11157376 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11157376 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11157376 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15769980 — Surrogate Endpoint (SUR): Blood pressure
Study 15769980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15769980 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15769980 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15769980 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7949088 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 11317156 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2