TrialPanorama/TrialPanorama-database huggingface dataset:
Study 6398982 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20620267 — Surrogate Endpoint (SUR): Blood pressure
Study 20620267 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28081673 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17252032 — Surrogate Endpoint (SUR): Blood pressure
Study 27124042 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10497374 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29289383 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 26968277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26968277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26968277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18366729 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 12455393 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7793224 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7793224 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 7332089 — Surrogate Endpoint (SUR): Blood pressure
Study 7946899 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27756419 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11396998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8498900 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 24942756 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18374336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1678518 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 24740733 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 31253226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31253226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21212103 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 17302367 — Monitoring Biomarker (MOI): HBV DNA
Study 11606512 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 17244767 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17244767 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15258553 — Surrogate Endpoint (SUR): Blood pressure
Study 23430102 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 15742550 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23874588 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17109339 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 29528961 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 29528961 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 9657569 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9657569 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31650487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31650487 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22378476 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 19763135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19763135 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15306713 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10480776 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10480776 — Surrogate Endpoint (SUR): Blood pressure
Study 1765940 — Surrogate Endpoint (SUR): Probing pocket depth
Study 6749427 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25589511 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 22535977 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 10361867 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 7627722 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 2021332 — Surrogate Endpoint (SUR): Serum potassium
Study 30953776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29038365 — Predictive Biomarker (PRD): SLC16A4 mRNA
Genes: SLC16A4; MCT4; MCT5
Study 29038365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 29038365 — Predictive Biomarker (PRD): SLC9A1 mRNA
Genes: SLC9A1; APNH1; NHE1
Study 29038365 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 29038365 — Safety Biomarker (SAF): Reactive oxygen species
Study 23695420 — Surrogate Endpoint (SUR): Bone mineral density
Study 11244019 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9285506 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 19756162 — Surrogate Endpoint (SUR): Blood pressure
Study 31184505 — Predictive Biomarker (PRD): CLN3 mRNA
Genes: CLN3; BTS
Study 28299514 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 21282537 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21282537 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8039271 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25615523 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 20609741 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20609741 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 20609741 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20609741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20609741 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20609741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8922912 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1416011 — Surrogate Endpoint (SUR): Blood pressure
Study 26806825 — Surrogate Endpoint (SUR): Blood pressure
Study 25351370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20354459 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20354459 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10780310 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 22579817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22579817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21030704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21030704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10421666 — Monitoring Biomarker (MOI): HBV DNA
Study 2508163 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 773584 — Surrogate Endpoint (SUR): Blood pressure
Study 25812845 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 16923230 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 12893078 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 12893078 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 12893078 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29221643 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20484157 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 18175750 — Surrogate Endpoint (SUR): Blood pressure
Study 30174413 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7533223 — Surrogate Endpoint (SUR): Blood pressure
Study 8399863 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 30501974 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29087285 — Surrogate Endpoint (SUR): Serum creatinine
Study 19351224 — Surrogate Endpoint (SUR): Serum uric acid
Study 16761193 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16761193 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 3326025 — Surrogate Endpoint (SUR): Blood pressure
Study 23659494 — Surrogate Endpoint (SUR): Blood pressure
Study 8546117 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8581377 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 8581377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12867383 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1824651 — Surrogate Endpoint (SUR): Blood pressure
Study 1824651 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1824651 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24451146 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 20002638 — Safety Biomarker (SAF): Hyaluronic acid
Study 16295781 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16295781 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12450894 — Surrogate Endpoint (SUR): Blood pressure
Study 28403362 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 28403362 — Safety Biomarker (SAF): Hyaluronic acid
Study 30593457 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 30593457 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28634659 — Surrogate Endpoint (SUR): Blood pressure
Study 19387178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2688764 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1103576 — Surrogate Endpoint (SUR): Blood pressure
Study 31270800 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28911799 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28911799 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 28911799 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28911799 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26609891 — Predictive Biomarker (PRD): HTR7 mRNA
Genes: HTR7
Study 23955418 — Surrogate Endpoint (SUR): Blood pressure
Study 19245725 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15590250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8076074 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 3525428 — Surrogate Endpoint (SUR): Blood pressure
Study 28636433 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28636433 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 28636433 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 25185281 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 18266852 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18266852 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18266852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30216238 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 17503668 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23638803 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10372230 — Surrogate Endpoint (SUR): Blood pressure
Study 22795291 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22795291 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21123342 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21123342 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28648577 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28648577 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 27793166 — Monitoring Biomarker (MOI): HBV DNA
Study 1858985 — Surrogate Endpoint (SUR): Blood pressure
Study 30820037 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 19175878 — Monitoring Biomarker (MOI): HBV DNA
Study 2666559 — Surrogate Endpoint (SUR): Blood pressure
Study 2666559 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25838254 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 21132438 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8515787 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26079223 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 19167636 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29528117 — Surrogate Endpoint (SUR): Blood pressure
Study 2919766 — Surrogate Endpoint (SUR): Blood pressure
Study 24187862 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 24187862 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25708022 — Surrogate Endpoint (SUR): Blood pressure
Study 21632496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2187327 — Surrogate Endpoint (SUR): Bone mineral density
Study 23479454 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21696889 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 19404631 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21788624 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8040674 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study 2522265 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2522265 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 2522265 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16896939 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 10770452 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24964358 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 24964358 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 2959232 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28755054 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30122646 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18042655 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 31115626 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 23553187 — Surrogate Endpoint (SUR): Blood pressure
Study 23977105 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20537762 — Predictive Biomarker (PRD): SPAG9 mRNA
Genes: SPAG9; HSS; KIAA0516; MAPK8IP4; SYD1; HLC6
Study 19440013 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 7523909 — Safety Biomarker (SAF): Hypoxanthine-guanine phosphoribosyltransferase
Genes: HPRT1; HPRT
Study 26714845 — Surrogate Endpoint (SUR): Blood pressure
Study 11763829 — Surrogate Endpoint (SUR): Blood pressure
Study 8529054 — Surrogate Endpoint (SUR): Blood pressure
Study 31655626 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 9100602 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9100602 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9100602 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9100602 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2516705 — Surrogate Endpoint (SUR): Serum testosterone
Study 31327753 — Surrogate Endpoint (SUR): Blood pressure
Study 16840826 — Surrogate Endpoint (SUR): Blood pressure
Study 8324945 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3462459 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16095461 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 16095461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16095461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12403958 — Surrogate Endpoint (SUR): Blood pressure
Study 28782697 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 21600592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21600592 — Surrogate Endpoint (SUR): Serum creatinine
Study 15267123 — Surrogate Endpoint (SUR): Bone mineral density
Study 11158861 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11158861 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11158861 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11158861 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 3103540 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 27492018 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 16494857 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 15259901 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 9298779 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9298779 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9298779 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9298779 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 7899804 — Surrogate Endpoint (SUR): Blood pressure
Study 25012543 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25012543 — Predictive Biomarker (PRD): EPAS1 mRNA
Genes: EPAS1; BHLHE73; HIF2A; MOP2; PASD2
Study 25012543 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 25012543 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study 25012543 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20361904 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 19368096 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19368096 — Surrogate Endpoint (SUR): Blood pressure
Study 30321061 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 29961161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29961161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24652989 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 24652989 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 21410035 — Surrogate Endpoint (SUR): Blood pressure
Study 12914870 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12914870 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12914870 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10340366 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10340366 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30193295 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30193295 — Predictive Biomarker (PRD): Hormone receptor
Study 24126365 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study 19399391 — Surrogate Endpoint (SUR): Blood pressure
Study 17415036 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15157254 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 16492007 — Surrogate Endpoint (SUR): Blood pressure
Study 6653649 — Surrogate Endpoint (SUR): Blood pressure
Study 31849296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31849296 — Surrogate Endpoint (SUR): Blood pressure
Study 27581760 — Surrogate Endpoint (SUR): Blood pressure
Study 21878834 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17043157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17043157 — Surrogate Endpoint (SUR): Blood pressure
Study 17043157 — Surrogate Endpoint (SUR): Serum potassium
Study 17043157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12959319 — Predictive Biomarker (PRD): PSD4 mRNA
Genes: PSD4; EFA6B; TIC
Study 27513278 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 27513278 — Surrogate Endpoint (SUR): Blood pressure
Study 25479899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22414053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10350664 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27583404 — Surrogate Endpoint (SUR): Blood pressure
Study 20565725 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 14607735 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 7485886 — Surrogate Endpoint (SUR): Blood pressure
Study 31492516 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 29425477 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29425477 — Surrogate Endpoint (SUR): Blood pressure
Study 12519875 — Surrogate Endpoint (SUR): Blood pressure
Study 12519875 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9169959 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 29769133 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14