TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18467621 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21306829 — Surrogate Endpoint (SUR): Blood pressure
Study 17578485 — Surrogate Endpoint (SUR): Blood pressure
Study 17578485 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 14969424 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 31852916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31852916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15817850 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 12613519 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 12613519 — Predictive Biomarker (PRD): UBR5 mRNA
Genes: UBR5; EDD; EDD1; HYD; KIAA0896
Study 9750444 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7625419 — Surrogate Endpoint (SUR): Bone mineral density
Study 2778913 — Surrogate Endpoint (SUR): Blood pressure
Study 31805256 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 20007431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20007431 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20007431 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 20007431 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 20007431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 20007431 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 20007431 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 20007431 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17622279 — Surrogate Endpoint (SUR): Blood pressure
Study 15908667 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 484753 — Surrogate Endpoint (SUR): Blood pressure
Study 30979559 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 25170012 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 22669546 — Surrogate Endpoint (SUR): Bone mineral density
Study 11779724 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 21055142 — Surrogate Endpoint (SUR): Blood pressure
Study 21055142 — Surrogate Endpoint (SUR): Serum testosterone
Study 12886670 — Surrogate Endpoint (SUR): Blood pressure
Study 1336516 — Surrogate Endpoint (SUR): Blood pressure
Study 29537447 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 18559703 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 26310261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26310261 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 26310261 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 19685943 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 6861846 — Surrogate Endpoint (SUR): Blood pressure
Study 20169359 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 20169359 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 16393332 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 10385012 — Predictive Biomarker (PRD): NSMAF mRNA
Genes: NSMAF; FAN
Study 16160131 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2355103 — Surrogate Endpoint (SUR): Blood pressure
Study 2355103 — Surrogate Endpoint (SUR): Serum potassium
Study 30927200 — Predictive Biomarker (PRD): CA4 mRNA
Genes: CA4
Study 8754956 — Predictive Biomarker (PRD): CEACAM6 mRNA
Genes: CEACAM6; NCA
Study 27157472 — Surrogate Endpoint (SUR): Bone mineral density
Study 8702053 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8702053 — Surrogate Endpoint (SUR): Serum creatinine
Study 1687130 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1687130 — Surrogate Endpoint (SUR): Blood pressure
Study 10559514 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17804334 — Predictive Biomarker (PRD): ZP3 mRNA
Genes: ZP3; ZP3A; ZP3B; ZPC
Study 16035374 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 332218 — Surrogate Endpoint (SUR): Blood pressure
Study 31494015 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 28344197 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19808130 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19808130 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11711507 — Surrogate Endpoint (SUR): Blood pressure
Study 29354988 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23595153 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21166598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18359215 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26985905 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10703776 — Surrogate Endpoint (SUR): Blood pressure
Study 8963728 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24824197 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10487502 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8598593 — Surrogate Endpoint (SUR): Blood pressure
Study 29121975 — Surrogate Endpoint (SUR): Blood pressure
Study 25557658 — Surrogate Endpoint (SUR): Bone mineral density
Study 31486833 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31486833 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22252217 — Surrogate Endpoint (SUR): Serum testosterone
Study 12915604 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10485635 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 6653642 — Surrogate Endpoint (SUR): Blood pressure
Study 30637907 — Surrogate Endpoint (SUR): Blood pressure
Study 29683755 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27687887 — Surrogate Endpoint (SUR): Blood pressure
Study 18769356 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7428802 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 28586162 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 10660238 — Surrogate Endpoint (SUR): Blood pressure
Study 8346818 — Surrogate Endpoint (SUR): Blood pressure
Study 2871945 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25511185 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 25511185 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 21046232 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7933491 — Surrogate Endpoint (SUR): Blood pressure
Study 2851177 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 23064980 — Surrogate Endpoint (SUR): Blood pressure
Study 15876900 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 1578946 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31478290 — Surrogate Endpoint (SUR): Blood pressure
Study 19246733 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17122621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10505743 — Predictive Biomarker (PRD): IFNAR1 mRNA
Genes: IFNAR1; IFNAR
Study 8726600 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12484804 — Surrogate Endpoint (SUR): Blood pressure
Study 1909810 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 6666842 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 20880345 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20880345 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20880345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8746601 — Surrogate Endpoint (SUR): Blood pressure
Study 28560832 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 10780760 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26276501 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 26276501 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21442611 — Surrogate Endpoint (SUR): Blood pressure
Study 16962881 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25205142 — Surrogate Endpoint (SUR): Blood pressure
Study 8507417 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24403477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8487326 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3031714 — Surrogate Endpoint (SUR): Blood pressure
Study 22387758 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 18217157 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 18217157 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 10811451 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 1808368 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25691036 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 25691036 — Predictive Biomarker (PRD): Liver iron
Study 7989637 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 21870174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23046525 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 23046525 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16164451 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15848504 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 9466503 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 30954304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25611207 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22886783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22886783 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19440073 — Surrogate Endpoint (SUR): Serum testosterone
Study 15823769 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 7930025 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26008690 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 11411653 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11411653 — Surrogate Endpoint (SUR): Blood pressure
Study 9121968 — Surrogate Endpoint (SUR): Blood pressure
Study 25389256 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18385420 — Surrogate Endpoint (SUR): Blood pressure
Study 16939743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31394921 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 16136469 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15207760 — Surrogate Endpoint (SUR): Bone mineral density
Study 16995864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25548079 — Safety Biomarker (SAF): Hyaluronic acid
Study 6908909 — Surrogate Endpoint (SUR): Blood pressure
Study 28506339 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 25391252 — Surrogate Endpoint (SUR): Blood pressure
Study 17761367 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 15489632 — Surrogate Endpoint (SUR): Blood pressure
Study 31115844 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31115844 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study 29161288 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 29161288 — Surrogate Endpoint (SUR): Bone mineral density
Study 24123845 — Surrogate Endpoint (SUR): Serum testosterone
Study 17881423 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1579228 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27160380 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 16237621 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30526600 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 2503018 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 21245130 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 21245130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19817198 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 18184041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18184041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9355902 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 3513518 — Surrogate Endpoint (SUR): Blood pressure
Study 23711288 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 10372738 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10372738 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 24670970 — Surrogate Endpoint (SUR): Blood pressure
Study 24670970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17622238 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17622238 — Predictive Biomarker (PRD): Hormone receptor
Study 15826438 — Surrogate Endpoint (SUR): Blood pressure
Study 25584994 — Surrogate Endpoint (SUR): Blood pressure
Study 11301186 — Predictive Biomarker (PRD): KLRD1 mRNA
Genes: KLRD1; CD94
Study 11301186 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11301186 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11301186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11301186 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 11301186 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 3882141 — Surrogate Endpoint (SUR): Blood pressure
Study 22500388 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22500388 — Surrogate Endpoint (SUR): Serum creatinine
Study 30223083 — Surrogate Endpoint (SUR): Blood pressure
Study 28838475 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28838475 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 28838475 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 28838475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28838475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28838475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25377657 — Surrogate Endpoint (SUR): Blood pressure
Study 15016023 — Surrogate Endpoint (SUR): Probing pocket depth
Study 3283620 — Predictive Biomarker (PRD): DNM1 mRNA
Genes: DNM1; DNM
Study 29413364 — Safety Biomarker (SAF): Interleukin 1
Study 28662808 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12888055 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 31905382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21131387 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19546825 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19546825 — Surrogate Endpoint (SUR): Bone mineral density
Study 8318063 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8318063 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 8318063 — Predictive Biomarker (PRD): HES1 mRNA
Genes: HES1; BHLHB39; HL; HRY
Study 20127900 — Surrogate Endpoint (SUR): Serum creatinine
Study 15232793 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 15232793 — Surrogate Endpoint (SUR): Serum calcium
Study 11716652 — Surrogate Endpoint (SUR): Blood pressure
Study 29540293 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 18545070 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15714981 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11760378 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 11760378 — Surrogate Endpoint (SUR): Serum methemoglobin
Study 23806212 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 23806212 — Predictive Biomarker (PRD): HSP90B1 mRNA
Genes: HSP90B1; GRP94; TRA1
Study 23806212 — Safety Biomarker (SAF): Cytochrome c
Study 11881701 — Surrogate Endpoint (SUR): Blood pressure
Study 17086764 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17086764 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 17086764 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 15536018 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9390698 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 23484524 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23484524 — Surrogate Endpoint (SUR): Blood pressure
Study 23484524 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20141706 — Surrogate Endpoint (SUR): Blood pressure
Study 27373 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 31879752 — Surrogate Endpoint (SUR): Blood pressure
Study 19619331 — Predictive Biomarker (PRD): IPO13 mRNA
Genes: IPO13; KIAA0724; RANBP13
Study 15232663 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9660383 — Surrogate Endpoint (SUR): Blood pressure
Study 8704425 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8704425 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27039945 — Surrogate Endpoint (SUR): Blood pressure
Study 27039945 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12534314 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 10921541 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10921541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20223500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16756149 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23767865 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11189683 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 3303916 — Surrogate Endpoint (SUR): Blood pressure
Study 27744141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27744141 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18072367 — Surrogate Endpoint (SUR): Blood pressure
Study 12074357 — Surrogate Endpoint (SUR): Blood pressure
Study 10583039 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 25163948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7821128 — Surrogate Endpoint (SUR): Blood pressure
Study 22382047 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22382047 — Surrogate Endpoint (SUR): Blood pressure
Study 15681602 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10641740 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10641740 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 1097489 — Surrogate Endpoint (SUR): Serum uric acid
Study 25819139 — Surrogate Endpoint (SUR): Blood pressure
Study 24618266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31758571 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 29665833 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29665833 — Surrogate Endpoint (SUR): Blood pressure
Study 23032305 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 23032305 — Safety Biomarker (SAF): DRD2
Study 11099170 — Surrogate Endpoint (SUR): Blood pressure
Study 4047384 — Surrogate Endpoint (SUR): Blood pressure
Study 26989892 — Surrogate Endpoint (SUR): Serum uric acid
Study 26989892 — Surrogate Endpoint (SUR): Serum creatinine
Study 16007562 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7832339 — Surrogate Endpoint (SUR): Blood pressure
Study 26372 — Surrogate Endpoint (SUR): Blood pressure
Study 23911139 — Surrogate Endpoint (SUR): Blood pressure
Study 18671798 — Surrogate Endpoint (SUR): Blood pressure
Study 11457745 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25243955 — Monitoring Biomarker (MOI): HBV DNA
Study 20388472 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18042503 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9012303 — Surrogate Endpoint (SUR): Blood pressure
Study 19625064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19625064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19625064 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28916534 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 20650654 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 20650654 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341