TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7851599 — Safety Biomarker (SAF): Reactive oxygen species
Study 19004549 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 19004549 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 2117858 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 2117858 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 26602322 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 22579409 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 26790823 — Surrogate Endpoint (SUR): Blood pressure
Study 19169140 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19952819 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1817663 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 24588434 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 9760009 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9760009 — Surrogate Endpoint (SUR): Blood pressure
Study 8156094 — Surrogate Endpoint (SUR): Blood pressure
Study 24895108 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21141289 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 17590511 — Surrogate Endpoint (SUR): Blood pressure
Study 3511382 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27789050 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 27789050 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27789050 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30508316 — Surrogate Endpoint (SUR): Bone mineral density
Study 22151836 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22151836 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15595588 — Surrogate Endpoint (SUR): Blood pressure
Study 30007054 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 25953073 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 18316791 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 18316791 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 6166800 — Surrogate Endpoint (SUR): Blood pressure
Study 26176605 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19168521 — Predictive Biomarker (PRD): ACOT7 mRNA
Genes: ACOT7; BACH
Study 9209608 — Surrogate Endpoint (SUR): Blood pressure
Study 3623678 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 3623678 — Surrogate Endpoint (SUR): Blood pressure
Study 19247742 — Surrogate Endpoint (SUR): Blood pressure
Study 15229391 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19117887 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16937109 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 25122693 — Surrogate Endpoint (SUR): Pathological complete response
Study 17454163 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10541948 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 10541948 — Predictive Biomarker (PRD): SLC35A2 mRNA
Genes: SLC35A2; UGALT; UGT; UGTL
Study 2129071 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26993316 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 27779565 — Surrogate Endpoint (SUR): Blood pressure
Study 27779565 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23999661 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 22165459 — Surrogate Endpoint (SUR): Blood pressure
Study 18998188 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 18998188 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15233286 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 8929232 — Surrogate Endpoint (SUR): Blood pressure
Study 28347792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28347792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28347792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17304143 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 8620046 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 31842962 — Surrogate Endpoint (SUR): Blood pressure
Study 31842962 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 19056078 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 17599420 — Surrogate Endpoint (SUR): Blood pressure
Study 17599420 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17599420 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15691617 — Surrogate Endpoint (SUR): Blood pressure
Study 8560527 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6104973 — Surrogate Endpoint (SUR): Blood pressure
Study 9597414 — Surrogate Endpoint (SUR): Blood pressure
Study 3302342 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 29581161 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 21151978 — Predictive Biomarker (PRD): AQP5 mRNA
Genes: AQP5
Study 8596757 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 8582499 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 635480 — Surrogate Endpoint (SUR): Bacterial count
Study 31769596 — Safety Biomarker (SAF): Hyaluronic acid
Study 26404912 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 21495198 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 21495198 — Surrogate Endpoint (SUR): Blood pressure
Study 28965280 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23883378 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21816062 — Monitoring Biomarker (MOI): HBV DNA
Study 8480900 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8480900 — Surrogate Endpoint (SUR): Blood pressure
Study 12884458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 13130389 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 13130389 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 13130389 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 10535718 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10535718 — Surrogate Endpoint (SUR): Blood pressure
Study 1745340 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 21823969 — Surrogate Endpoint (SUR): Blood pressure
Study 19152452 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19152452 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 19152452 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 2272708 — Surrogate Endpoint (SUR): Blood pressure
Study 24253250 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 24253250 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 24253250 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 24253250 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 24253250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7924126 — Surrogate Endpoint (SUR): Blood pressure
Study 531993 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 31867908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31867908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19427810 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 15100514 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12714834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27502307 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16315242 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 31724191 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29739385 — Surrogate Endpoint (SUR): Blood pressure
Study 29931852 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31482193 — Surrogate Endpoint (SUR): Bone mineral density
Study 25677355 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 15097245 — Surrogate Endpoint (SUR): Blood pressure
Study 3122919 — Surrogate Endpoint (SUR): Blood pressure
Study 30516328 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 19383110 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16772451 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 7957481 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 29728201 — Surrogate Endpoint (SUR): Blood pressure
Study 18503806 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10893357 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9042260 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27487437 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17396118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7994791 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 2623077 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 24127622 — Surrogate Endpoint (SUR): Blood pressure
Study 19690081 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15526248 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11474540 — Surrogate Endpoint (SUR): Blood pressure
Study 9506192 — Surrogate Endpoint (SUR): Blood pressure
Study 29501740 — Surrogate Endpoint (SUR): Blood pressure
Study 27259675 — Predictive Biomarker (PRD): SRY mRNA
Genes: SRY; TDF
Study 20130841 — Surrogate Endpoint (SUR): Bone mineral density
Study 18070142 — Surrogate Endpoint (SUR): Blood pressure
Study 9235072 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9235072 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9235072 — Surrogate Endpoint (SUR): Blood pressure
Study 31358540 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31358540 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 24532394 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 10804328 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 8778696 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 8065177 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28068165 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24243632 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 25534331 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25534331 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 25534331 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 1844749 — Surrogate Endpoint (SUR): Blood pressure
Study 29134635 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 1380411 — Surrogate Endpoint (SUR): Blood pressure
Study 6873004 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 11952586 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22672107 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 11151749 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 16024863 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1837496 — Surrogate Endpoint (SUR): Blood pressure
Study 6122652 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 24152604 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 21781598 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 11355930 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29673375 — Predictive Biomarker (PRD): SLC25A3 mRNA
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 24810476 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1596903 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25292404 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 24874483 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 24874483 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 20933301 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 20860505 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28693985 — Surrogate Endpoint (SUR): Blood pressure
Study 16014056 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26466804 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26466804 — Surrogate Endpoint (SUR): Blood pressure
Study 19644045 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27516541 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 26543236 — Predictive Biomarker (PRD): CD2AP mRNA
Genes: CD2AP
Study 26543236 — Predictive Biomarker (PRD): SORL1 mRNA
Genes: SORL1; C11orf32
Study 26543236 — Predictive Biomarker (PRD): FERMT2 mRNA
Genes: FERMT2; KIND2; MIG2; PLEKHC1
Study 26543236 — Predictive Biomarker (PRD): NECTIN2 mRNA
Genes: NECTIN2; HVEB; PRR2; PVRL2
Study 26543236 — Predictive Biomarker (PRD): TOMM40 mRNA
Genes: TOMM40; C19orf1; PEREC1; TOM40
Study 26543236 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 20705785 — Surrogate Endpoint (SUR): Blood pressure
Study 12393590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31978689 — Surrogate Endpoint (SUR): Blood pressure
Study 31791637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31791637 — Surrogate Endpoint (SUR): Blood pressure
Study 25141360 — Surrogate Endpoint (SUR): Blood pressure
Study 19910177 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10900277 — Safety Biomarker (SAF): Reactive oxygen species
Study 10900277 — Surrogate Endpoint (SUR): Serum creatinine
Study 8922661 — Surrogate Endpoint (SUR): Bone mineral density
Study 30847930 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22318199 — Predictive Biomarker (PRD): Liver iron
Study 12975409 — Surrogate Endpoint (SUR): Blood pressure
Study 9032849 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31142081 — Surrogate Endpoint (SUR): Blood pressure
Study 2844546 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31276454 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 7986390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25924668 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8339215 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27637335 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27637335 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 24378525 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23043944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 28882471 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26133666 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12464983 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9475259 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9475259 — Surrogate Endpoint (SUR): Blood pressure
Study 8529851 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8529851 — Surrogate Endpoint (SUR): Blood pressure
Study 28841649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28841649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24235105 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 18957613 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18957613 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 9890856 — Surrogate Endpoint (SUR): Serum creatinine
Study 7783051 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24094768 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24094768 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18179503 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 3901535 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3901535 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 31615181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28825508 — Predictive Biomarker (PRD): MEST mRNA
Genes: MEST; PEG1
Study 26066525 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23239968 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17845256 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29447737 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28668412 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8702050 — Surrogate Endpoint (SUR): Blood pressure
Study 31026384 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25439136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22739142 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 22739142 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 22739142 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22739142 — Surrogate Endpoint (SUR): Blood pressure
Study 11187914 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1283570 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1283570 — Surrogate Endpoint (SUR): Blood pressure
Study 28623849 — Surrogate Endpoint (SUR): Serum creatinine
Study 16921051 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29317418 — Surrogate Endpoint (SUR): Blood pressure
Study 7740021 — Surrogate Endpoint (SUR): Blood pressure
Study 26261640 — Surrogate Endpoint (SUR): Blood pressure
Study 21436337 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 16646673 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16646673 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 8890945 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 27298569 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 27298569 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 27298569 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 25330631 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 18775608 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 12879220 — Surrogate Endpoint (SUR): Bone mineral density
Study 11694861 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3351300 — Surrogate Endpoint (SUR): Blood pressure
Study 23307511 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21768905 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 27133033 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 27133033 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 22344575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20620742 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20620742 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 20620742 — Surrogate Endpoint (SUR): Blood pressure
Study 7572771 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 64803 — Surrogate Endpoint (SUR): Blood pressure
Study 64803 — Surrogate Endpoint (SUR): Serum potassium
Study 30793440 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24462960 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 16084882 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 31605515 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 25844619 — Surrogate Endpoint (SUR): Bone mineral density
Study 19508653 — Surrogate Endpoint (SUR): Blood pressure
Study 25384603 — Surrogate Endpoint (SUR): Serum creatinine
Study 25384603 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 11212970 — Surrogate Endpoint (SUR): Blood pressure
Study 28645713 — Surrogate Endpoint (SUR): Blood pressure
Study 21612749 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 21612749 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17925114 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15089817 — Surrogate Endpoint (SUR): Blood pressure
Study 1286640 — Surrogate Endpoint (SUR): Blood pressure
Study 17845588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 12488405 — Predictive Biomarker (PRD): Hormone receptor
Study 9798529 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9798529 — Surrogate Endpoint (SUR): Blood pressure
Study 20537740 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 20537740 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2423794 — Surrogate Endpoint (SUR): Blood pressure
Study 24241787 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21178084 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21178084 — Surrogate Endpoint (SUR): Blood pressure
Study 10634672 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30012431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30012431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21707679 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 14685870 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 2121104 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26332798 — Surrogate Endpoint (SUR): Bone mineral density