TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01679899 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03096782 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03662750 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT00169221 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02967601 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00046553 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT04365933 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT00429897 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03867682 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT01242566 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00493961 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study NCT02964585 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02706210 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01595594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03861156 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00120328 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03276234 — Surrogate Endpoint (SUR): Serum sodium
Study NCT02585947 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02892890 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study NCT03412643 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03464149 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT03464149 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03464149 — Surrogate Endpoint (SUR): Serum phosphate
Study NCT03464149 — Surrogate Endpoint (SUR): Serum calcium
Study NCT03464149 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT03921333 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03468894 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03468894 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02886559 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01478698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01949519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01949519 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT01949519 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study NCT04668365 — Predictive Biomarker (PRD): CD79A mRNA
Genes: CD79A; IGA; MB1
Study NCT04668365 — Predictive Biomarker (PRD): CD79B mRNA
Genes: CD79B; B29; IGB
Study NCT04191252 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT00898690 — Predictive Biomarker (PRD): LZTS1 mRNA
Genes: LZTS1; FEZ1
Study NCT04638036 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02798198 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00801827 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT02077023 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02308904 — Predictive Biomarker (PRD): Liver iron
Study NCT01772563 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02643745 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02004106 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02004106 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01010997 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04829968 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04532762 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03782610 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00820729 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01457846 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT05082415 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05082415 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03311074 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT03431194 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00529503 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT01051791 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03379558 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT00436956 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03827850 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT03827850 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT03827850 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02526537 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02526537 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03368235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05168137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04571086 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT00840957 — Predictive Biomarker (PRD): FCGRT mRNA
Genes: FCGRT; FCRN
Study NCT00840957 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study NCT00840957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00000415 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02621008 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03260803 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03260803 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03260803 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT03260803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): NRF2 mRNA
Genes: NFE2L2; NRF2
Study NCT03502876 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00668538 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT00668538 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04189029 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03834220 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT03834220 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT03834220 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT03834220 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT02062645 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04377399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04377399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01478776 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study NCT01478776 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT01478776 — Predictive Biomarker (PRD): C5AR2 mRNA
Genes: C5AR2; C5L2; GPR77
Study NCT01126541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02829359 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01113164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT02848144 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00778869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05012514 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study NCT02561559 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT03883087 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00852241 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03369236 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT01364311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT01364311 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01364311 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01627379 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01332747 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02996825 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT02984995 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04354831 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05663489 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study NCT00726167 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT05063513 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05520957 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03459560 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04186052 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT01306656 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01691547 — Surrogate Endpoint (SUR): Serum potassium
Study NCT04865614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00953511 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT00226434 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01646671 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00559897 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT02558595 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT01646034 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT00015951 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00015951 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00701805 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT01536808 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00652457 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03636490 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04865510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01540812 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01540812 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02133144 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study NCT02133144 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT02133144 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT03372005 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02415582 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00443794 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00443794 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03898817 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study NCT03898817 — Predictive Biomarker (PRD): RECQL4 mRNA
Genes: RECQL4; RECQ4
Study NCT05115994 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03175705 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT01146288 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01778920 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT04487977 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00952965 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04016129 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT04016129 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT01777945 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03429257 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study NCT01966445 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT03561597 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04297072 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00680485 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study NCT00680485 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01277315 — Safety Biomarker (SAF): Interleukin 1
Study NCT04010968 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00417560 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03806452 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02179814 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT04151810 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01951521 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01214681 — Predictive Biomarker (PRD): GADD45A mRNA
Genes: GADD45A; DDIT1; GADD45
Study NCT01214681 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT01214681 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT01214681 — Predictive Biomarker (PRD): SFRP1 mRNA
Genes: SFRP1; FRP; FRP1; SARP2
Study NCT01214681 — Predictive Biomarker (PRD): AXIN2 mRNA
Genes: AXIN2
Study NCT00788359 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04452773 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02291809 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02291809 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02703467 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00928291 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01498783 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT04431219 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study NCT00352378 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03561714 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04633785 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00665769 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00675038 — Predictive Biomarker (PRD): Liver iron
Study NCT02720185 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02720185 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00599222 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02007811 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02983877 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01942434 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study NCT00001909 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT00001909 — Safety Biomarker (SAF): Th2 cell
Study NCT01300988 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT01300988 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00413413 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00764140 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00513981 — Surrogate Endpoint (SUR): Plasma methotrexate
Study NCT00656825 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study NCT02492204 — Predictive Biomarker (PRD): IL33 mRNA
Genes: IL33; C9orf26; IL1F11; NFHEV
Study NCT02492204 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT03090971 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00320814 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03065608 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01828359 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01994408 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03726931 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT03726931 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03298399 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02073669 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04288700 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04507971 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04507971 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01462877 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01462877 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02627768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03433183 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT04436484 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00760916 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02230293 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06149377 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06149377 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT06149377 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02839694 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study NCT02027753 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03866980 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03866980 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03866980 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02630381 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01557140 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01288547 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00735072 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00735072 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02705547 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT04086992 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02139904 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03871972 — Predictive Biomarker (PRD): ZMPSTE24
Genes: FACE-1; Ste24p; STE24; HGPS; PRO1
Study NCT02386267 — Predictive Biomarker (PRD): RPL35A mRNA
Genes: RPL35A; GIG33
Study NCT02386267 — Predictive Biomarker (PRD): RPL11 mRNA
Genes: RPL11
Study NCT02386267 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02672592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02672592 — Safety Biomarker (SAF): Interleukin 1
Study NCT02672592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04543656 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00866281 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01042652 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04112693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03154697 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study NCT04650828 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02705950 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT02272998 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT02272998 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT02272998 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02272998 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02523833 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT02881892 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02881892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02881892 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00083928 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT02870348 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT03511924 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study NCT04832763 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00627991 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00774488 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01403116 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00123045 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01402063 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00263406 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01976143 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT00094848 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT01020253 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03993496 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02930187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00424554 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT01482481 — Surrogate Endpoint (SUR): Blood pressure