TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11263387 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 7869303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30249314 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15983180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15983180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15983180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6108175 — Surrogate Endpoint (SUR): Serum potassium
Study 6108175 — Surrogate Endpoint (SUR): Blood pressure
Study 24946565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10601505 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3698511 — Surrogate Endpoint (SUR): Blood pressure
Study 17853009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17853009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17853009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17853009 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12623509 — Surrogate Endpoint (SUR): Blood pressure
Study 12623509 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12623509 — Surrogate Endpoint (SUR): Serum creatinine
Study 6763404 — Surrogate Endpoint (SUR): Blood pressure
Study 11275936 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11275936 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 11275936 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 28930494 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 19809382 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 31194613 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18644399 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27224474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27224474 — Monitoring Biomarker (MOI): Procalcitonin
Study 27224474 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19736368 — Surrogate Endpoint (SUR): Blood pressure
Study 17606774 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 11854876 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11854876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11854876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7029294 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 30939480 — Surrogate Endpoint (SUR): Blood pressure
Study 30939480 — Surrogate Endpoint (SUR): Serum creatinine
Study 25919263 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 24067390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21851939 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 21851939 — Predictive Biomarker (PRD): LIFR mRNA
Genes: LIFR
Study 21851939 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 7641905 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7641905 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31563959 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31563959 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 31563959 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study 31563959 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31563959 — Predictive Biomarker (PRD): Hormone receptor
Study 28537654 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28537654 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15082472 — Surrogate Endpoint (SUR): Blood pressure
Study 11360489 — Surrogate Endpoint (SUR): Blood pressure
Study 29931216 — Surrogate Endpoint (SUR): Bone mineral density
Study 26285021 — Surrogate Endpoint (SUR): Blood pressure
Study 12843154 — Surrogate Endpoint (SUR): Bone mineral density
Study 12843154 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10993857 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10993857 — Surrogate Endpoint (SUR): Blood pressure
Study 8869661 — Surrogate Endpoint (SUR): Blood pressure
Study 8869661 — Safety Biomarker (SAF): 51Cr-EDTA
Study 6860528 — Surrogate Endpoint (SUR): Blood pressure
Study 27045864 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22076422 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3927279 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29394147 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24323615 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24323615 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 20585108 — Surrogate Endpoint (SUR): Blood pressure
Study 12050273 — Safety Biomarker (SAF): Reactive oxygen species
Study 10690807 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 27631388 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 27631388 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17664863 — Surrogate Endpoint (SUR): Serum sodium
Study 17664863 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16105056 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 16105056 — Surrogate Endpoint (SUR): Serum calcium
Study 10199774 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12373416 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 10404500 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 10404500 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10404500 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29738417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29738417 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23163117 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8803643 — Surrogate Endpoint (SUR): Blood pressure
Study 1465278 — Predictive Biomarker (PRD): Hormone receptor
Study 25785316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8706484 — Surrogate Endpoint (SUR): Serum creatinine
Study 30168415 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15051595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15051595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15051595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29921143 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 27730819 — Surrogate Endpoint (SUR): Blood pressure
Study 24478129 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 24478129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24478129 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 29118060 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29118060 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29118060 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26324220 — Surrogate Endpoint (SUR): Blood pressure
Study 30917364 — Surrogate Endpoint (SUR): Blood pressure
Study 24433061 — Surrogate Endpoint (SUR): Blood pressure
Study 16154305 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11873030 — Surrogate Endpoint (SUR): Blood pressure
Study 7595856 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 2112480 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 28970080 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28970080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24132975 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19745163 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 19745163 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 19745163 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 8435984 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29083443 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25342738 — Surrogate Endpoint (SUR): Blood pressure
Study 22959058 — Predictive Biomarker (PRD): HSPA1A mRNA
Genes: HSPA1A; HSP72; HSPA1; HSX70
Study 22959058 — Predictive Biomarker (PRD): PDIA3 mRNA
Genes: PDIA3; ERP57; ERP60; GRP58
Study 22959058 — Predictive Biomarker (PRD): PSME1 mRNA
Genes: PSME1; IFI5111
Study 22959058 — Predictive Biomarker (PRD): SMC6 mRNA
Genes: SMC6; SMC6L1
Study 22959058 — Predictive Biomarker (PRD): ECH1 mRNA
Genes: ECH1
Study 18226561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7554761 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31743812 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 17630552 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9643054 — Surrogate Endpoint (SUR): Blood pressure
Study 28494751 — Surrogate Endpoint (SUR): Blood pressure
Study 25143719 — Surrogate Endpoint (SUR): Serum testosterone
Study 22421906 — Surrogate Endpoint (SUR): Blood pressure
Study 12639061 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 2121359 — Safety Biomarker (SAF): L-acetylcarnitine
Study 26118476 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 26118476 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26118476 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 15001599 — Surrogate Endpoint (SUR): Blood pressure
Study 22257673 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22257673 — Surrogate Endpoint (SUR): Pathological complete response
Study 16154442 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10895854 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6541251 — Surrogate Endpoint (SUR): Blood pressure
Study 17632305 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 11400949 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 25536598 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23525426 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30696812 — Predictive Biomarker (PRD): ADGRL3 mRNA
Genes: ADGRL3; KIAA0768; LEC3; LPHN3
Study 10862538 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 8880362 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1907056 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 12699137 — Surrogate Endpoint (SUR): Blood pressure
Study 24327037 — Surrogate Endpoint (SUR): Blood pressure
Study 25858265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25858265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23298304 — Safety Biomarker (SAF): Hyaluronic acid
Study 9215249 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7897254 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 19150019 — Surrogate Endpoint (SUR): Blood pressure
Study 9862250 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26815944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18853230 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1557595 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 1557595 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 31988233 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 31988233 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31988233 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31988233 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26255814 — Surrogate Endpoint (SUR): Blood pressure
Study 23589163 — Surrogate Endpoint (SUR): Bone mineral density
Study 15837454 — Surrogate Endpoint (SUR): Bone mineral density
Study 12544411 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18781850 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 18781850 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 18781850 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16373648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 14760042 — Surrogate Endpoint (SUR): Blood pressure
Study 10958125 — Surrogate Endpoint (SUR): Blood pressure
Study 22660798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18612266 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 1759005 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 25797743 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 25797743 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 29083258 — Surrogate Endpoint (SUR): Bone mineral density
Study 21960311 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 18519268 — Surrogate Endpoint (SUR): Bone mineral density
Study 26990694 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 24572452 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 24572452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24572452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24572452 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22013959 — Safety Biomarker (SAF): Hyaluronic acid
Study 17604562 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 15083437 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 8458802 — Surrogate Endpoint (SUR): Blood pressure
Study 30714092 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 22588152 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28051341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21534640 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21534640 — Surrogate Endpoint (SUR): Blood pressure
Study 18162322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16340480 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 16340480 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16340480 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 16340480 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 20223872 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18024537 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2571595 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 2571595 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2571595 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17503661 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 28437029 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26604214 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 12198060 — Surrogate Endpoint (SUR): Blood pressure
Study 31013275 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 23594362 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23594362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11264734 — Monitoring Biomarker (MOI): HBV DNA
Study 2474100 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2474100 — Surrogate Endpoint (SUR): Blood pressure
Study 28729361 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19820590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19820590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25408998 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14738659 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 25807399 — Surrogate Endpoint (SUR): Blood pressure
Study 24338186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21471106 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12653261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 6327513 — Surrogate Endpoint (SUR): Blood pressure
Study 27320538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27320538 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27320538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27320538 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24569538 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 17608844 — Surrogate Endpoint (SUR): Blood pressure
Study 2158410 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2158410 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17701883 — Predictive Biomarker (PRD): ATP7B mRNA
Genes: ATP7B; PWD; WC1; WND
Study 19320245 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16626956 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30835327 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12826844 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 12826844 — Surrogate Endpoint (SUR): Blood pressure
Study 22339661 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 20150520 — Surrogate Endpoint (SUR): Blood pressure
Study 7772916 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21337541 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 21337541 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 21337541 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 21337541 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 21337541 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 22194590 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19923521 — Surrogate Endpoint (SUR): Blood pressure
Study 9140209 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9140209 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30738417 — Surrogate Endpoint (SUR): Blood pressure
Study 31192555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31192555 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 18304285 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 18304285 — Predictive Biomarker (PRD): SEPTIN6 mRNA
Genes: SEPTIN6; KIAA0128; SEP2; SEPT6
Study 18304285 — Predictive Biomarker (PRD): SEPTIN3 mRNA
Genes: SEPTIN3; SEP3; SEPT3
Study 26250833 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 26250833 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 23218065 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21349192 — Surrogate Endpoint (SUR): Blood pressure
Study 19047545 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8155409 — Surrogate Endpoint (SUR): Bone mineral density
Study 22538186 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17038074 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9375336 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3236329 — Surrogate Endpoint (SUR): Blood pressure
Study 29687553 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 3140592 — Surrogate Endpoint (SUR): Blood pressure
Study 26125448 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 18253905 — Safety Biomarker (SAF): Hyaluronic acid
Study 17175820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25418492 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR