TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23604641 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 15065610 — Surrogate Endpoint (SUR): Bone mineral density
Study 1586175 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20860555 — Surrogate Endpoint (SUR): Blood pressure
Study 12187615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12187615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9674734 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 9674734 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 18047764 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 12748244 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28560383 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 28560383 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 21491420 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11276370 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11276370 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 11276370 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9135927 — Surrogate Endpoint (SUR): Serum triglycerides
Study 3315645 — Surrogate Endpoint (SUR): Blood pressure
Study 9754184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 12787037 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 25478993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25478993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25478993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25478993 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25478993 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24112149 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12575608 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30445454 — Safety Biomarker (SAF): Reactive oxygen species
Study 25895588 — Surrogate Endpoint (SUR): Blood pressure
Study 15243006 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 12821971 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22542608 — Safety Biomarker (SAF): Reactive oxygen species
Study 12028405 — Monitoring Biomarker (MOI): HBV DNA
Study 9820260 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 29188483 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 8755321 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 4008417 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 4008417 — Surrogate Endpoint (SUR): Blood pressure
Study 26122834 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 12949382 — Surrogate Endpoint (SUR): Blood pressure
Study 1892491 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6441716 — Surrogate Endpoint (SUR): Serum potassium
Study 28414493 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 20613670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20613670 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 20613670 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28597604 — Surrogate Endpoint (SUR): Serum creatinine
Study 31815677 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29470151 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22779217 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19756479 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20821332 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 20821332 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 9563140 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27535128 — Surrogate Endpoint (SUR): Blood pressure
Study 27535128 — Surrogate Endpoint (SUR): Serum creatinine
Study 20674303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20674303 — Surrogate Endpoint (SUR): Blood pressure
Study 8124787 — Surrogate Endpoint (SUR): Blood pressure
Study 31860856 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 28601891 — Surrogate Endpoint (SUR): Blood pressure
Study 28601891 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19706565 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 17609906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17609906 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17609906 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11405601 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15848600 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15848600 — Surrogate Endpoint (SUR): Blood pressure
Study 9037790 — Predictive Biomarker (PRD): HYLS1 mRNA
Genes: HYLS1; HLS
Study 28632394 — Predictive Biomarker (PRD): RGL1 mRNA
Genes: RGL1; KIAA0959; RGL
Study 16507195 — Surrogate Endpoint (SUR): Blood pressure
Study 3907322 — Surrogate Endpoint (SUR): Blood pressure
Study 3907322 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15973769 — Monitoring Biomarker (MOI): HBV DNA
Study 15377133 — Surrogate Endpoint (SUR): Blood pressure
Study 508556 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 28682277 — Surrogate Endpoint (SUR): Blood pressure
Study 19723649 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11574740 — Surrogate Endpoint (SUR): Blood pressure
Study 16855066 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16855066 — Predictive Biomarker (PRD): RAB11FIP1 mRNA
Genes: RAB11FIP1; RCP
Study 16855066 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 10637531 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 9310806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9310806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2446061 — Surrogate Endpoint (SUR): Blood pressure
Study 23411609 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18643006 — Surrogate Endpoint (SUR): Blood pressure
Study 14580925 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1389989 — Predictive Biomarker (PRD): TEP1 mRNA
Genes: TEP1; TLP1; TP1
Study 30977496 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 30977496 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16131376 — Predictive Biomarker (PRD): NAAA mRNA
Genes: NAAA; ASAHL; PLT
Study 27881297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26484516 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26484516 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 16179042 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 25837216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24028998 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 19750191 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 16894423 — Surrogate Endpoint (SUR): Serum creatinine
Study 26996093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23979965 — Monitoring Biomarker (MOI): HBV DNA
Study 23979965 — Surrogate Endpoint (SUR): Serum creatinine
Study 1715125 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24556041 — Surrogate Endpoint (SUR): Serum creatinine
Study 22445676 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22445676 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 18602754 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31127593 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 25918728 — Surrogate Endpoint (SUR): Blood pressure
Study 31125491 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31125491 — Predictive Biomarker (PRD): GSTM3 mRNA
Genes: GSTM3; GST5
Study 31125491 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 26915064 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19267777 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 15309009 — Surrogate Endpoint (SUR): Blood pressure
Study 3207788 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 18442788 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27903339 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24794140 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 24794140 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 3039842 — Surrogate Endpoint (SUR): Blood pressure
Study 23814135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23814135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19321584 — Surrogate Endpoint (SUR): Blood pressure
Study 17042662 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 17042662 — Surrogate Endpoint (SUR): Serum creatinine
Study 3067105 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 23590163 — Surrogate Endpoint (SUR): Blood pressure
Study 20153489 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 9842243 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28816881 — Surrogate Endpoint (SUR): Blood pressure
Study 18192898 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 23539724 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20065185 — Predictive Biomarker (PRD): Hormone receptor
Study 20065185 — Surrogate Endpoint (SUR): Bone mineral density
Study 17080224 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17080224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17080224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17080224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17080224 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17080224 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 3028458 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29708589 — Surrogate Endpoint (SUR): Blood pressure
Study 14648269 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25041994 — Predictive Biomarker (PRD): SLC19A1 mRNA
Genes: SLC19A1; FLOT1; RFC1
Study 25041994 — Predictive Biomarker (PRD): SHMT1 mRNA
Genes: SHMT1
Study 25041994 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 25041994 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 25041994 — Safety Biomarker (SAF): MTHFR
Study 25041994 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 14693299 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 6958478 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6958478 — Surrogate Endpoint (SUR): Serum creatinine
Study 2261966 — Predictive Biomarker (PRD): PEPD mRNA
Genes: PEPD; PRD
Study 2261966 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 2261966 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27151015 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27151015 — Surrogate Endpoint (SUR): Serum creatinine
Study 17635377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8149689 — Surrogate Endpoint (SUR): Blood pressure
Study 16875911 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 11055473 — Surrogate Endpoint (SUR): Blood pressure
Study 11055473 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 3756064 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 3756064 — Surrogate Endpoint (SUR): Blood pressure
Study 31473512 — Predictive Biomarker (PRD): CHDH mRNA
Genes: CHDH
Study 31473512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): BHMT mRNA
Genes: BHMT
Study 29712560 — Surrogate Endpoint (SUR): Blood pressure
Study 29712560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29712560 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10736328 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21188596 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 21188596 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 9534983 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 9534983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 490883 — Surrogate Endpoint (SUR): Blood pressure
Study 23391776 — Surrogate Endpoint (SUR): Blood pressure
Study 21921208 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9202101 — Surrogate Endpoint (SUR): Blood pressure
Study 25614603 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25614603 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 29336914 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 27630211 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 30216846 — Surrogate Endpoint (SUR): Blood pressure
Study 30216846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30216846 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 27049103 — Safety Biomarker (SAF): Hyaluronic acid
Study 18093199 — Safety Biomarker (SAF): Hyaluronic acid
Study 11095476 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 1350796 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1350796 — Surrogate Endpoint (SUR): Blood pressure
Study 4083464 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31221297 — Surrogate Endpoint (SUR): Blood pressure
Study 3903732 — Surrogate Endpoint (SUR): Blood pressure
Study 22768458 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 12043306 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 12043306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12043306 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12043306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10541326 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 343006 — Surrogate Endpoint (SUR): Blood pressure
Study 23568174 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15274385 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14517197 — Surrogate Endpoint (SUR): Blood pressure
Study 29885911 — Safety Biomarker (SAF): Hyaluronic acid
Study 27725121 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27725121 — Safety Biomarker (SAF): BDNF
Study 27725121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19065894 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19065894 — Surrogate Endpoint (SUR): Serum creatinine
Study 24608017 — Surrogate Endpoint (SUR): Blood pressure
Study 22658758 — Surrogate Endpoint (SUR): Serum testosterone
Study 12196363 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 30394240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21323568 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21323568 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21323568 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 17827829 — Surrogate Endpoint (SUR): Blood pressure
Study 27459586 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15801995 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 15801995 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8873692 — Surrogate Endpoint (SUR): Blood pressure
Study 17580145 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17580145 — Surrogate Endpoint (SUR): Serum creatinine
Study 16383040 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10082174 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 20217203 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12095312 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 12095312 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 7774076 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 2078806 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12424539 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31614036 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 22341703 — Surrogate Endpoint (SUR): Blood pressure
Study 2656908 — Monitoring Biomarker (MOI): HBV DNA
Study 29141376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29141376 — Monitoring Biomarker (MOI): Procalcitonin
Study 29141376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25961614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23090093 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 23090093 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 15120937 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 2969799 — Surrogate Endpoint (SUR): Blood pressure
Study 12057040 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12057040 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24640801 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20964826 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8578731 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8578731 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8578731 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 347467 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 24834865 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 19156894 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 8792735 — Surrogate Endpoint (SUR): Bone mineral density
Study 16688997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16688997 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 2412032 — Surrogate Endpoint (SUR): Blood pressure
Study 31376917 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26910293 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 17611095 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 6469428 — Surrogate Endpoint (SUR): Blood pressure
Study 6469428 — Surrogate Endpoint (SUR): Serum potassium
Study 29847330 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8529087 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31534549 — Predictive Biomarker (PRD): DNMT3B mRNA
Genes: DNMT3B
Study 31534549 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 31534549 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 27348000 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 27348000 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 14716219 — Surrogate Endpoint (SUR): Blood pressure
Study 9677460 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30889607 — Surrogate Endpoint (SUR): Bacterial count
Study 28222558 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 16368878 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16368878 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 16368878 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11057441 — Surrogate Endpoint (SUR): Blood pressure
Study 11057441 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3034032 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3034032 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 3034032 — Surrogate Endpoint (SUR): Blood pressure
Study 8907443 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8907443 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 8907443 — Surrogate Endpoint (SUR): Blood pressure
Study 25588704 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7595909 — Surrogate Endpoint (SUR): Blood pressure
Study 23479422 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22640563 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH