TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03318913 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01446003 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01853371 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04615312 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02154243 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02361957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00950716 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02684084 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03282630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00756717 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00693589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03825744 — Surrogate Endpoint (SUR): Hematologic response
Study NCT01157234 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04083534 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04763096 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01304979 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT00257101 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02784808 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02426437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02426437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00159419 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00724360 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04124276 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT04235114 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04235114 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03857880 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT00080431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00080431 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00080431 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02124824 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT02710214 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04053114 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT00357968 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT00260689 — Surrogate Endpoint (SUR): Hematologic response
Study NCT05124496 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00374049 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT03015740 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00464113 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00464113 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03455517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01022333 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03010072 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT02937363 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT04536337 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01843309 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT01921335 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03702660 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02150356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01911247 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT00707317 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04021043 — Predictive Biomarker (PRD): TNFRSF18 mRNA
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study NCT04021043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00913679 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00051831 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03564938 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03564938 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00889382 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT01835535 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02522052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04727775 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00556699 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT01206465 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT00089427 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT05210140 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03031834 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01095224 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05732948 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05732948 — Predictive Biomarker (PRD): PSCA mRNA
Genes: PSCA; UNQ206/PRO232
Study NCT01890967 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01890967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01890967 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05995379 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02956421 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01204125 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT00645151 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01043354 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04752930 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03547817 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02121041 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00412516 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02305173 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00791986 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03788356 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05308368 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT01287715 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study NCT00987025 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04871867 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02400515 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00494663 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02562014 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04366596 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03081910 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study NCT03081910 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT01421771 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02860936 — Predictive Biomarker (PRD): MYB mRNA
Genes: MYB
Study NCT02860936 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT02860936 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT02860936 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02860936 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03311919 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study NCT00030407 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05685017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05685017 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT00876356 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04336332 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03446599 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT00069030 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01380587 — Predictive Biomarker (PRD): XCL1 mRNA
Genes: XCL1; LTN; SCYC1
Study NCT00003431 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02762994 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT03634059 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02822482 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02822482 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02268006 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02626208 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study NCT01790217 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02010294 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT01811368 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04229290 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04413968 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03686215 — Predictive Biomarker (PRD): LUM mRNA
Genes: LUM; LDC; SLRR2D
Study NCT02721719 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02721719 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00646503 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00063258 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03498924 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT03498924 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT03498924 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00402025 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00962286 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00035555 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04360707 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04234061 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05067959 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00582790 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03477383 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study NCT02963480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02963480 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT00337987 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01899326 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT01221077 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01221077 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05143684 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00995956 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02838745 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT02838745 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT03794778 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05184179 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00217334 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03194334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02821949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02821949 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02251353 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT02455128 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03438006 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03438006 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01598545 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00350987 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03666325 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03666325 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03989011 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study NCT03209024 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03610919 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study NCT01706718 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04390230 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01215903 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04522999 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01841073 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT01841073 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01287455 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02438540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02438540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02438540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02438540 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02438540 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02438540 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04499378 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00792233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04044209 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT04141644 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02742051 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02742051 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03580382 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT03580382 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT02711462 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04517591 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02522117 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02522117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00578695 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01696565 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01030094 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01030094 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02958930 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04712292 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02572453 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02572453 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study NCT00287638 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00287638 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT00798655 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00798655 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00798655 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04095806 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00867854 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03778008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT06177587 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study NCT01099306 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05020106 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02809768 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02111434 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02111434 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00006228 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00006228 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01083862 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00269334 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00269334 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01859026 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01859026 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03909399 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT01857453 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT02235610 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT02335268 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT04390464 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04612595 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00960934 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00960934 — Surrogate Endpoint (SUR): Serum calcium
Study NCT00700245 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study NCT00700245 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study NCT00700245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00700245 — Safety Biomarker (SAF): Interleukin 1
Study NCT00700245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01736748 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03635983 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT04253821 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00291473 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04505826 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04505826 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04505826 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01432028 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study NCT01432028 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT01432028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01432028 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04183101 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04183101 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT04183101 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01784380 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT01104571 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02050035 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04815018 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02941588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT03177187 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study NCT01985464 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04629274 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02853539 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01989676 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02156960 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04502849 — Safety Biomarker (SAF): Cytochrome c
Study NCT04053673 — Predictive Biomarker (PRD): TIPARP mRNA
Genes: TIPARP; PARP7
Study NCT03702634 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02977156 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT02977156 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02377388 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01708655 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7