TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17369566 — Surrogate Endpoint (SUR): Bone mineral density
Study 11903415 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11903415 — Surrogate Endpoint (SUR): Blood pressure
Study 3310725 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26975947 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26275982 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9039083 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3443139 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 3443139 — Surrogate Endpoint (SUR): Blood pressure
Study 3443139 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3443139 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16162746 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2803413 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 31877968 — Surrogate Endpoint (SUR): Blood pressure
Study 31877968 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31877968 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17725931 — Surrogate Endpoint (SUR): Blood pressure
Study 15282383 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15282383 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 29772084 — Monitoring Biomarker (MOI): HBV DNA
Study 20593498 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27694633 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23165609 — Surrogate Endpoint (SUR): Bone mineral density
Study 19693532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16887418 — Surrogate Endpoint (SUR): Serum creatinine
Study 8751015 — Surrogate Endpoint (SUR): Blood pressure
Study 17118092 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26658237 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 22293363 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15788369 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15788369 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 15788369 — Predictive Biomarker (PRD): CYP3A7 mRNA
Genes: CYP3A7
Study 24169960 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 12760406 — Surrogate Endpoint (SUR): Serum creatinine
Study 30787665 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 19050692 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17215658 — Surrogate Endpoint (SUR): Blood pressure
Study 17215658 — Surrogate Endpoint (SUR): Serum potassium
Study 14713367 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15893183 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 15893183 — Surrogate Endpoint (SUR): Blood pressure
Study 12637127 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21786162 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23282127 — Surrogate Endpoint (SUR): Blood pressure
Study 16954725 — Surrogate Endpoint (SUR): Blood pressure
Study 9508155 — Surrogate Endpoint (SUR): Blood pressure
Study 29989014 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 18498919 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18498919 — Surrogate Endpoint (SUR): Blood pressure
Study 18498919 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23349309 — Predictive Biomarker (PRD): AFF1 mRNA
Genes: AFF1; AF4; FEL; MLLT2; PBM1
Study 23349309 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21315644 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 19827653 — Surrogate Endpoint (SUR): Blood pressure
Study 30898938 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 12161101 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7637157 — Surrogate Endpoint (SUR): Blood pressure
Study 21052690 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21052690 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21052690 — Predictive Biomarker (PRD): CASP1 mRNA
Genes: CASP1; IL1BC; IL1BCE
Study 21052690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16721686 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7572630 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 6119025 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 31442395 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31562049 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31562049 — Safety Biomarker (SAF): BDNF
Study 31562049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28961832 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28961832 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26167086 — Surrogate Endpoint (SUR): Serum creatinine
Study 26167086 — Surrogate Endpoint (SUR): Serum uric acid
Study 26167086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24506429 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 24506429 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 24506429 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24506429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16893378 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10385063 — Surrogate Endpoint (SUR): Bone mineral density
Study 15983331 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 19846743 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19846743 — Surrogate Endpoint (SUR): Bone mineral density
Study 31247643 — Predictive Biomarker (PRD): PTGES mRNA
Genes: PTGES; MGST1L1; MPGES1; PGES; PIG12
Study 29618599 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29618599 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15866643 — Surrogate Endpoint (SUR): Bone mineral density
Study 8184812 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26582645 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 26582645 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 26582645 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study 18234127 — Surrogate Endpoint (SUR): Bone mineral density
Study 12595913 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12595913 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 12595913 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8991564 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 8325071 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3792347 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29929385 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19002314 — Surrogate Endpoint (SUR): Blood pressure
Study 12885747 — Surrogate Endpoint (SUR): Blood pressure
Study 1752075 — Surrogate Endpoint (SUR): Hematologic response
Study 28911144 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17904989 — Predictive Biomarker (PRD): SPTB mRNA
Genes: SPTB; SPTB1
Study 8873539 — Surrogate Endpoint (SUR): Blood pressure
Study 1415367 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20164112 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19438584 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 30632656 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21133820 — Surrogate Endpoint (SUR): Blood pressure
Study 17234518 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 10518847 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 27508917 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11837383 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8665543 — Surrogate Endpoint (SUR): Blood pressure
Study 1706014 — Surrogate Endpoint (SUR): Blood pressure
Study 28751244 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 14508197 — Surrogate Endpoint (SUR): Blood pressure
Study 8968432 — Surrogate Endpoint (SUR): Blood pressure
Study 1319735 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11703423 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31274491 — Surrogate Endpoint (SUR): Blood pressure
Study 24460005 — Surrogate Endpoint (SUR): Bone mineral density
Study 19223559 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 6165954 — Surrogate Endpoint (SUR): Blood pressure
Study 15702140 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 30004570 — Surrogate Endpoint (SUR): Bone mineral density
Study 18035199 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 18035199 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10490784 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 1657501 — Surrogate Endpoint (SUR): Blood pressure
Study 22699241 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 17683868 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11807960 — Surrogate Endpoint (SUR): Blood pressure
Study 8075030 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31221534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31221534 — Surrogate Endpoint (SUR): Blood pressure
Study 21246844 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 8309864 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1676367 — Surrogate Endpoint (SUR): Blood pressure
Study 30151703 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 30151703 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 22944391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9663215 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 2509528 — Surrogate Endpoint (SUR): Blood pressure
Study 31404623 — Surrogate Endpoint (SUR): Blood pressure
Study 28987023 — Safety Biomarker (SAF): Hyaluronic acid
Study 8665547 — Safety Biomarker (SAF): DRD2
Study 2183619 — Surrogate Endpoint (SUR): Blood pressure
Study 24026600 — Surrogate Endpoint (SUR): Blood pressure
Study 12535752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12535752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9039444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29423540 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29423540 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 29423540 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 18797094 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 20928906 — Predictive Biomarker (PRD): MYF6 mRNA
Genes: MYF6; BHLHC4; MRF4
Study 10227009 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30022544 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 25167977 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25167977 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30177038 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 26808546 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26808546 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26808546 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26808546 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 26808546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26808546 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 24115735 — Surrogate Endpoint (SUR): Blood pressure
Study 20484334 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16339586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 28756115 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26786311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24163081 — Surrogate Endpoint (SUR): Blood pressure
Study 15086284 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31551192 — Safety Biomarker (SAF): miR-137
Genes: MIR137
Study 27745812 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 16053850 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16053850 — Surrogate Endpoint (SUR): Blood pressure
Study 11943931 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 10065788 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 10065788 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2207824 — Surrogate Endpoint (SUR): Blood pressure
Study 29121415 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 29121415 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study 29121415 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 23536942 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 18687385 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 16184836 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 29379278 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 27893109 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 8871884 — Monitoring Biomarker (MOI): HBV DNA
Study 4063689 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 3365327 — Surrogate Endpoint (SUR): Blood pressure
Study 18615004 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 18615004 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 15542574 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 18378136 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 15653378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12716753 — Predictive Biomarker (PRD): LIPE mRNA
Genes: LIPE
Study 12716753 — Surrogate Endpoint (SUR): Serum creatinine
Study 12716753 — Surrogate Endpoint (SUR): Blood pressure
Study 22972835 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 20806117 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11875316 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11875316 — Surrogate Endpoint (SUR): Blood pressure
Study 181258 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28549783 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 28549783 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8140565 — Surrogate Endpoint (SUR): Blood pressure
Study 20225536 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20225536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16249460 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 8767563 — Surrogate Endpoint (SUR): Blood pressure
Study 27790530 — Predictive Biomarker (PRD): EBP mRNA
Genes: EBP
Study 22349389 — Surrogate Endpoint (SUR): Blood pressure
Study 22349389 — Surrogate Endpoint (SUR): Serum creatinine
Study 22349389 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18156406 — Safety Biomarker (SAF): MTHFR
Study 16628625 — Monitoring Biomarker (MOI): HBV DNA
Study 18524784 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 18524784 — Predictive Biomarker (PRD): SPIN1 mRNA
Genes: SPIN1; OCR; SPIN
Study 18524784 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7852526 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29557414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29557414 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26489835 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 24944159 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 10333347 — Surrogate Endpoint (SUR): Blood pressure
Study 7795831 — Surrogate Endpoint (SUR): Blood pressure
Study 28525534 — Surrogate Endpoint (SUR): Pathological complete response
Study 25915145 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 22108775 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15311147 — Surrogate Endpoint (SUR): Blood pressure
Study 3093915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26842902 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24576226 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 11939913 — Predictive Biomarker (PRD): ARX mRNA
Genes: ARX
Study 2144819 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2144819 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 28898281 — Monitoring Biomarker (MOI): HBV DNA
Study 25805647 — Surrogate Endpoint (SUR): Blood pressure
Study 7542301 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11322176 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9478089 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 3307517 — Surrogate Endpoint (SUR): Blood pressure
Study 29157872 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 26154547 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23846759 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 23846759 — Surrogate Endpoint (SUR): Blood pressure
Study 17047401 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17047401 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17047401 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12767538 — Surrogate Endpoint (SUR): Blood pressure
Study 9021380 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 9021380 — Surrogate Endpoint (SUR): Bone mineral density
Study 30894213 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 30894213 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19678777 — Surrogate Endpoint (SUR): Blood pressure
Study 11344184 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9700978 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9700978 — Surrogate Endpoint (SUR): Blood pressure
Study 28365238 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28365238 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 10700656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10700656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10700656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9568324 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9568324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30097359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18506677 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16430197 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16430197 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16430197 — Surrogate Endpoint (SUR): Serum creatinine
Study 30567626 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 16784967 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16784967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8691923 — Surrogate Endpoint (SUR): Blood pressure
Study 7114076 — Monitoring Biomarker (MOI): Complement C4
Study 26672246 — Surrogate Endpoint (SUR): Blood pressure
Study 11477729 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 3059882 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study 25312436 — Surrogate Endpoint (SUR): Blood pressure
Study 16320073 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 29521134 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29521134 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 12568205 — Surrogate Endpoint (SUR): Blood pressure
Study 8580622 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 138578 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 138578 — Surrogate Endpoint (SUR): Blood pressure
Study 31248548 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 30168004 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 24560135 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 24560135 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 20636275 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12696650 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31027300 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21062616 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15776301 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 9875580 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 7840322 — Safety Biomarker (SAF): Interleukin 1
Study 27631386 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 25978742 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 19297309 — Surrogate Endpoint (SUR): Blood pressure
Study 12968238 — Surrogate Endpoint (SUR): Serum creatinine
Study 1623694 — Surrogate Endpoint (SUR): Blood pressure