TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23912950 — Surrogate Endpoint (SUR): Bone mineral density
Study 11227969 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7719761 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 27763895 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27763895 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27763895 — Surrogate Endpoint (SUR): Serum creatinine
Study 11484451 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 3948545 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18840257 — Surrogate Endpoint (SUR): Blood pressure
Study 16505224 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16505224 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 16505224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11815726 — Surrogate Endpoint (SUR): Bone mineral density
Study 11815726 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11815726 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24464746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28371338 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19884716 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 19884716 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 11753747 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 31222540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22422607 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25567 — Surrogate Endpoint (SUR): Blood pressure
Study 16839346 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 3880585 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 18441707 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 12680863 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12680863 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 9629968 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 22260244 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18283138 — Surrogate Endpoint (SUR): Blood pressure
Study 30718952 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 30718952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24172265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24172265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24172265 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18808404 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 18808404 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 2064495 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2064495 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24827136 — Predictive Biomarker (PRD): SERPINB3 mRNA
Genes: SERPINB3; SCCA; SCCA1
Study 1659494 — Surrogate Endpoint (SUR): Blood pressure
Study 30912737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 29503075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27034958 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17379048 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8136642 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 8136642 — Surrogate Endpoint (SUR): Blood pressure
Study 23803341 — Surrogate Endpoint (SUR): Bone mineral density
Study 16917115 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 14687247 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9428435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29708031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21797795 — Surrogate Endpoint (SUR): Blood pressure
Study 21797795 — Surrogate Endpoint (SUR): Serum uric acid
Study 21797795 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18772269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12580651 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 2595800 — Surrogate Endpoint (SUR): Blood pressure
Study 25436620 — Surrogate Endpoint (SUR): Blood pressure
Study 24872136 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24872136 — Surrogate Endpoint (SUR): Bone mineral density
Study 24872136 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24872136 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21748366 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 29035677 — Surrogate Endpoint (SUR): Blood pressure
Study 29035677 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15282385 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14673683 — Surrogate Endpoint (SUR): Blood pressure
Study 20299336 — Surrogate Endpoint (SUR): Serum creatinine
Study 9800929 — Surrogate Endpoint (SUR): Blood pressure
Study 29901322 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 29901322 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study 22429760 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 3516017 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26109727 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9640079 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 9640079 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9640079 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22483976 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22483976 — Surrogate Endpoint (SUR): Blood pressure
Study 18767339 — Surrogate Endpoint (SUR): Blood pressure
Study 16471186 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31679431 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study 31679431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 31679431 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22124355 — Surrogate Endpoint (SUR): Blood pressure
Study 10477441 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28234969 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21383283 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21383283 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15543081 — Surrogate Endpoint (SUR): Blood pressure
Study 10517716 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10517716 — Surrogate Endpoint (SUR): Bone mineral density
Study 1837785 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29380922 — Surrogate Endpoint (SUR): Blood pressure
Study 21242652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19617271 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19617271 — Surrogate Endpoint (SUR): Blood pressure
Study 15138344 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 11789591 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study 16793810 — Surrogate Endpoint (SUR): Blood pressure
Study 3009077 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31128875 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 29482642 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29482642 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 29482642 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 29482642 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20139427 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 20139427 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20139427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20139427 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 18248661 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2333832 — Surrogate Endpoint (SUR): Blood pressure
Study 28397083 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 15850856 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 24353345 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 12088970 — Surrogate Endpoint (SUR): Blood pressure
Study 1844926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28965157 — Surrogate Endpoint (SUR): Blood pressure
Study 11932655 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2081010 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 2081010 — Surrogate Endpoint (SUR): Blood pressure
Study 31062349 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26497508 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 24570986 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21339698 — Surrogate Endpoint (SUR): Bone mineral density
Study 21339698 — Surrogate Endpoint (SUR): Serum calcium
Study 19462277 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22436957 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 16437721 — Surrogate Endpoint (SUR): Serum sodium
Study 8604274 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15814336 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 25624436 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 28619294 — Surrogate Endpoint (SUR): Serum creatinine
Study 28619294 — Surrogate Endpoint (SUR): Blood pressure
Study 8681311 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 1822833 — Surrogate Endpoint (SUR): Blood pressure
Study 20194854 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17642435 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15226779 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7579505 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24865870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17360767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17360767 — Surrogate Endpoint (SUR): Blood pressure
Study 15723979 — Surrogate Endpoint (SUR): Blood pressure
Study 9831693 — Surrogate Endpoint (SUR): Blood pressure
Study 2525328 — Surrogate Endpoint (SUR): Blood pressure
Study 27577549 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study 30381400 — Surrogate Endpoint (SUR): Bone mineral density
Study 27310955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27310955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23187888 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18690118 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 18690118 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 18690118 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 18690118 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 18690118 — Safety Biomarker (SAF): DRD2
Study 12705643 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12705643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24677163 — Surrogate Endpoint (SUR): Blood pressure
Study 18603344 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18832432 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 18832432 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 12214580 — Surrogate Endpoint (SUR): Serum potassium
Study 2611358 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 976306 — Surrogate Endpoint (SUR): Blood pressure
Study 17093162 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 8133793 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8133793 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31983626 — Surrogate Endpoint (SUR): Blood pressure
Study 15964061 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15964061 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11074888 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1346337 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27885532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23067910 — Surrogate Endpoint (SUR): Blood pressure
Study 17522584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16225722 — Surrogate Endpoint (SUR): Blood pressure
Study 12403039 — Surrogate Endpoint (SUR): Blood pressure
Study 10189324 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30243957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26449884 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 2644746 — Surrogate Endpoint (SUR): Serum calcium
Study 11579272 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8067791 — Safety Biomarker (SAF): Interleukin 1
Study 8067791 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8067791 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30738795 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21813917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21813917 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8342392 — Surrogate Endpoint (SUR): Bone mineral density
Study 22016919 — Predictive Biomarker (PRD): CLSTN3 mRNA
Genes: CLSTN3; CS3; KIAA0726
Study 19690310 — Predictive Biomarker (PRD): Hormone receptor
Study 11505119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20384435 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8889350 — Surrogate Endpoint (SUR): Blood pressure
Study 8889350 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6678824 — Surrogate Endpoint (SUR): Blood pressure
Study 28248850 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 28248850 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25035343 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 27913408 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 18381313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10780766 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 1361250 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10658936 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10658936 — Surrogate Endpoint (SUR): Blood pressure
Study 2042792 — Surrogate Endpoint (SUR): Blood pressure
Study 26976971 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 18060441 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 10587552 — Surrogate Endpoint (SUR): Bone mineral density
Study 25725179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25725179 — Surrogate Endpoint (SUR): Serum creatinine
Study 11300448 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11300448 — Surrogate Endpoint (SUR): Blood pressure
Study 3524548 — Surrogate Endpoint (SUR): Blood pressure
Study 30396557 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 3927960 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26421929 — Predictive Biomarker (PRD): CSAD mRNA
Genes: CSAD; CSD
Study 15541082 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 28686006 — Surrogate Endpoint (SUR): Blood pressure
Study 9459112 — Surrogate Endpoint (SUR): Blood pressure
Study 2463689 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 2463689 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11727073 — Predictive Biomarker (PRD): CLNK mRNA
Genes: CLNK; MIST
Study 31153107 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19623570 — Surrogate Endpoint (SUR): Blood pressure
Study 26505826 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24948345 — Surrogate Endpoint (SUR): Serum calcium
Study 20920295 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 8931831 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8931831 — Surrogate Endpoint (SUR): Blood pressure
Study 30394919 — Surrogate Endpoint (SUR): Blood pressure
Study 29577973 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 24092385 — Surrogate Endpoint (SUR): Blood pressure
Study 17588297 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8396204 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24068395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24068395 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19912736 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19912736 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19912736 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11439963 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 15718840 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14521596 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1894758 — Surrogate Endpoint (SUR): Blood pressure
Study 26925155 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26925155 — Surrogate Endpoint (SUR): Blood pressure
Study 22247116 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30194031 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 30194031 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30194031 — Surrogate Endpoint (SUR): Serum testosterone
Study 30951597 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 30951597 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30951597 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28661759 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 15708302 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 342691 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31190359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25597870 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21729238 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21729238 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24446242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17400981 — Surrogate Endpoint (SUR): Blood pressure
Study 15567812 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9789972 — Surrogate Endpoint (SUR): Blood pressure
Study 18633170 — Surrogate Endpoint (SUR): Blood pressure
Study 18633170 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 31614909 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 31614909 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 15167732 — Surrogate Endpoint (SUR): Blood pressure
Study 19959168 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19959168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19959168 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19959168 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16280273 — Surrogate Endpoint (SUR): Blood pressure
Study 7785755 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6246620 — Surrogate Endpoint (SUR): Blood pressure
Study 28898379 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23478273 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11451594 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29617836 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 25154151 — Surrogate Endpoint (SUR): Blood pressure
Study 18334511 — Surrogate Endpoint (SUR): Serum creatinine
Study 23720367 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19299808 — Surrogate Endpoint (SUR): Blood pressure
Study 3279968 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 17548729 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10436966 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET