TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25487561 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 25487561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 18525395 — Surrogate Endpoint (SUR): Blood pressure
Study 11207478 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 11207478 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 11207478 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8487654 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8487654 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 3104750 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3104750 — Surrogate Endpoint (SUR): Blood pressure
Study 24006239 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20555305 — Surrogate Endpoint (SUR): Blood pressure
Study 10804025 — Surrogate Endpoint (SUR): Bone mineral density
Study 28537769 — Predictive Biomarker (PRD): KSR2 mRNA
Genes: KSR2
Study 21092958 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 17584667 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 10723506 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2616205 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30587963 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 19236695 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19236695 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9264500 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8405850 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12657339 — Surrogate Endpoint (SUR): Blood pressure
Study 1411317 — Surrogate Endpoint (SUR): Serum creatinine
Study 3516163 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31667693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31667693 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28425497 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 19960134 — Surrogate Endpoint (SUR): Blood pressure
Study 21303308 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 14666387 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28410749 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15385016 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15385016 — Surrogate Endpoint (SUR): Blood pressure
Study 8390528 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8390528 — Surrogate Endpoint (SUR): Blood pressure
Study 24983306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24983306 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30943824 — Surrogate Endpoint (SUR): Blood pressure
Study 25540980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 25540980 — Surrogate Endpoint (SUR): Blood pressure
Study 18626487 — Surrogate Endpoint (SUR): Blood pressure
Study 1425899 — Surrogate Endpoint (SUR): Blood pressure
Study 10657576 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10657576 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6706438 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9258760 — Surrogate Endpoint (SUR): Bone mineral density
Study 29206136 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14759561 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11549203 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16787138 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 28611089 — Surrogate Endpoint (SUR): Blood pressure
Study 28611089 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10713626 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10713626 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30221566 — Predictive Biomarker (PRD): SRGN mRNA
Genes: SRGN; PRG; PRG1
Study 30221566 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22011557 — Surrogate Endpoint (SUR): Blood pressure
Study 19284124 — Surrogate Endpoint (SUR): Blood pressure
Study 6793373 — Surrogate Endpoint (SUR): Blood pressure
Study 23217036 — Surrogate Endpoint (SUR): Blood pressure
Study 10216808 — Surrogate Endpoint (SUR): Blood pressure
Study 7797830 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26707295 — Surrogate Endpoint (SUR): Serum creatinine
Study 26707295 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21813916 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 28258090 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28258090 — Surrogate Endpoint (SUR): Blood pressure
Study 15030266 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 1413136 — Surrogate Endpoint (SUR): Blood pressure
Study 1413136 — Surrogate Endpoint (SUR): Serum triglycerides
Study 1413136 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18399897 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18399897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7091898 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19523212 — Predictive Biomarker (PRD): GDA mRNA
Genes: GDA; KIAA1258
Study 15496697 — Surrogate Endpoint (SUR): Blood pressure
Study 2848652 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2848652 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 18696157 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 28049190 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 12777589 — Surrogate Endpoint (SUR): Bone mineral density
Study 3532756 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25255587 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25255587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8546282 — Surrogate Endpoint (SUR): Blood pressure
Study 2468931 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2468931 — Surrogate Endpoint (SUR): Blood pressure
Study 27397061 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25644328 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 7756706 — Surrogate Endpoint (SUR): Serum creatinine
Study 26822630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30993400 — Surrogate Endpoint (SUR): Bone mineral density
Study 31532100 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 31532100 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25677713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24004639 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24004639 — Surrogate Endpoint (SUR): Blood pressure
Study 24004639 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24004639 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11345386 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26480664 — Surrogate Endpoint (SUR): Blood pressure
Study 21682834 — Surrogate Endpoint (SUR): Bone mineral density
Study 11333290 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7704288 — Surrogate Endpoint (SUR): Blood pressure
Study 10340371 — Surrogate Endpoint (SUR): Blood pressure
Study 2523657 — Surrogate Endpoint (SUR): Blood pressure
Study 17485570 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23193678 — Predictive Biomarker (PRD): CNBP mRNA
Genes: CNBP; RNF163; ZNF9
Study 17567623 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15205720 — Surrogate Endpoint (SUR): Bone mineral density
Study 15745109 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 15745109 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 11785558 — Surrogate Endpoint (SUR): Blood pressure
Study 2301245 — Surrogate Endpoint (SUR): Blood pressure
Study 15257846 — Surrogate Endpoint (SUR): Blood pressure
Study 2549243 — Surrogate Endpoint (SUR): Blood pressure
Study 25450993 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22455636 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 1756271 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 17122448 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1810080 — Surrogate Endpoint (SUR): Bone mineral density
Study 30528802 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30528802 — Surrogate Endpoint (SUR): Pathological complete response
Study 28198120 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28198120 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1654136 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29886354 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 29886354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27920497 — Surrogate Endpoint (SUR): Blood pressure
Study 23682544 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23682544 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17572410 — Surrogate Endpoint (SUR): Bone mineral density
Study 10572288 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 10572288 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 2828458 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 2828458 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26336931 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 2554244 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28878181 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19773666 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 18818679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30556339 — Surrogate Endpoint (SUR): Blood pressure
Study 21544882 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15177812 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 12408210 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 28063795 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 24358799 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 15947531 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9932938 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 7014694 — Surrogate Endpoint (SUR): Bacterial count
Study 27029919 — Predictive Biomarker (PRD): ATG7 mRNA
Genes: ATG7; APG7L
Study 27029919 — Predictive Biomarker (PRD): CASP3 mRNA
Genes: CASP3; CPP32
Study 25822100 — Predictive Biomarker (PRD): PER1 mRNA
Genes: PER1; KIAA0482; PER; RIGUI
Study 25822100 — Predictive Biomarker (PRD): PER2 mRNA
Genes: PER2; KIAA0347
Study 25822100 — Predictive Biomarker (PRD): PER3 mRNA
Genes: PER3; GIG13
Study 25822100 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 25822100 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25822100 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CD180 mRNA
Genes: CD180; LY64; RP105
Study 25822100 — Predictive Biomarker (PRD): NFKBIA mRNA
Genes: NFKBIA; IKBA; MAD3; NFKBI
Study 25822100 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 25822100 — Predictive Biomarker (PRD): ACOX3 mRNA
Genes: ACOX3; BRCOX; PRCOX
Study 25822100 — Predictive Biomarker (PRD): IDH3A mRNA
Genes: IDH3A
Study 21445638 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26608067 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26608067 — Surrogate Endpoint (SUR): Serum creatinine
Study 25559355 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17717057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26572168 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 26572168 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 26572168 — Predictive Biomarker (PRD): TFAM mRNA
Genes: TFAM; TCF6; TCF6L2
Study 6701249 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 29785045 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 26946725 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23712600 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23712600 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21504975 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 7772369 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7772369 — Surrogate Endpoint (SUR): Blood pressure
Study 2298969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 31504587 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 20147572 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 10864908 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10864908 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 10864908 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10864908 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26748872 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 17911462 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 17911462 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17911462 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 21198725 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12585985 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9035467 — Surrogate Endpoint (SUR): Blood pressure
Study 9035467 — Surrogate Endpoint (SUR): Serum potassium
Study 27999852 — Surrogate Endpoint (SUR): Blood pressure
Study 26289163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16294574 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 11238259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3685071 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3685071 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31038216 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study 10382948 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10382948 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29806538 — Predictive Biomarker (PRD): PRLR mRNA
Genes: PRLR
Study 26446239 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26446239 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 26446239 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20847699 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10651671 — Surrogate Endpoint (SUR): Blood pressure
Study 29597198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15848557 — Surrogate Endpoint (SUR): Serum creatinine
Study 12080961 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29099680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29099680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29099680 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17536077 — Surrogate Endpoint (SUR): Blood pressure
Study 6351901 — Surrogate Endpoint (SUR): Blood pressure
Study 29355679 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 20142520 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16364826 — Surrogate Endpoint (SUR): Blood pressure
Study 6802875 — Surrogate Endpoint (SUR): Blood pressure
Study 28171856 — Surrogate Endpoint (SUR): Blood pressure
Study 21874537 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21874537 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17934877 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 10611140 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10611140 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 10611140 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10611140 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 10611140 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 9360003 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9360003 — Surrogate Endpoint (SUR): Blood pressure
Study 22892123 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20980920 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20980920 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19526764 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19526764 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8572869 — Surrogate Endpoint (SUR): Blood pressure
Study 30874378 — Surrogate Endpoint (SUR): Blood pressure
Study 28579225 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10571341 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1725891 — Surrogate Endpoint (SUR): Blood pressure
Study 31609422 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 24684838 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24684838 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22669289 — Predictive Biomarker (PRD): FFAR1 mRNA
Genes: FFAR1; GPR40
Study 15851648 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22914998 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22914998 — Surrogate Endpoint (SUR): Blood pressure
Study 20837464 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20837464 — Surrogate Endpoint (SUR): Blood pressure
Study 17697909 — Predictive Biomarker (PRD): Liver iron
Study 7614647 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7614647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2517323 — Predictive Biomarker (PRD): SERPINF2 mRNA
Genes: SERPINF2; AAP; PLI
Study 1013675 — Surrogate Endpoint (SUR): Blood pressure
Study 20579542 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20579542 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8956920 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 3294081 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31016613 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 31016613 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23706433 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30695288 — Predictive Biomarker (PRD): GRAMD4 mRNA
Genes: GRAMD4; DIP; KIAA0767
Study 29383596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19604092 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 11403730 — Surrogate Endpoint (SUR): Blood pressure
Study 9717054 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9717054 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2488099 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28690088 — Surrogate Endpoint (SUR): Serum creatinine
Study 9415540 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9415540 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9415540 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9415540 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 8214746 — Surrogate Endpoint (SUR): Blood pressure
Study 21123447 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 20630505 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 15899653 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15899653 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9523214 — Predictive Biomarker (PRD): FMR1
Genes: FMRP; FRAXA; MGC87458
Study 11009291 — Surrogate Endpoint (SUR): Blood pressure
Study 8629306 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1424170 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 29307093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7508065 — Surrogate Endpoint (SUR): Blood pressure
Study 7508065 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25515398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20459697 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 20459697 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 16146552 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16146552 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29044707 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29044707 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 24667664 — Surrogate Endpoint (SUR): Blood pressure
Study 24667664 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24667664 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1