TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01015248 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT03790800 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02262351 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02761811 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00804882 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03972839 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT06161792 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01782313 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT04038489 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04038489 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04038489 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00577122 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03076138 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03076138 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01134939 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00964847 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02559388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03542851 — Predictive Biomarker (PRD): BTD mRNA
Genes: BTD
Study NCT04586179 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00554827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00780221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04138719 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04138719 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00539422 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02768025 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT02075944 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02075944 — Safety Biomarker (SAF): BDNF
Study NCT02597010 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04401670 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT03576105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03636750 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03636750 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study NCT03636750 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01567488 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study NCT04340882 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04340882 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00576030 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02963493 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT02135575 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00568477 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05122117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05122117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02807181 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT04316182 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04316182 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT04316182 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00957801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02003625 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03766100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01708772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04350892 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study NCT03242473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01051960 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01282593 — Predictive Biomarker (PRD): CD9 mRNA
Genes: CD9; MIC3; TSPAN29; GIG2
Study NCT03485560 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00915798 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study NCT04552340 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00430001 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01636713 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT01636713 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03780959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00247455 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01791361 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00378703 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00378703 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT02206126 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02023671 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT01349062 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01349062 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT01277484 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT02285231 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02019875 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01918969 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01918969 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04279145 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02643823 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00003075 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT00003075 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00155818 — Predictive Biomarker (PRD): DISC1 mRNA
Genes: DISC1; KIAA0457
Study NCT00110812 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00110812 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01500369 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00219037 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02601092 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT03298828 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00202904 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02425124 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03904459 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03161561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03038464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04724083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04724083 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study NCT00906451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04035564 — Surrogate Endpoint (SUR): Serum sodium
Study NCT03922308 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT03041142 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03333148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03333148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03333148 — Safety Biomarker (SAF): Interleukin 1
Study NCT03333148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03560323 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03274518 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT00219882 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01998893 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04400383 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT01468337 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02763930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02763930 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01077297 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03421743 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04570839 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study NCT03455829 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01939132 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01792973 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04006301 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04367714 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00527020 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT02933138 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00248430 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00248430 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04913701 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03794284 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT00826267 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04074941 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03150719 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01430585 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01430585 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01430585 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT04528446 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00299780 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02278445 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT06357988 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH
Study NCT06357988 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study NCT02544334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02983006 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT02983006 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study NCT02252627 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02310672 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03894384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study NCT02745717 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT01531946 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT01110629 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT04094233 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03476616 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02917720 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02917720 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00841399 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01006304 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT03993626 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04432805 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04042272 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT01897545 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01627990 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03667885 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study NCT02706028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00012051 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00101101 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00101101 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01217112 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01217112 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03494036 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT03494036 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT01492634 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04488978 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04341974 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04043195 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04043195 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03043677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01971346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04888065 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04888065 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT04888065 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03892798 — Predictive Biomarker (PRD): IRF2BPL mRNA
Genes: IRF2BPL; C14orf4; EAP1; KIAA1865; My039
Study NCT00140387 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02626026 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT02626026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02338934 — Surrogate Endpoint (SUR): Serum calcium
Study NCT03999242 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study NCT01843244 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00554866 — Safety Biomarker (SAF): Carbamoyl-phosphate synthetase I
Genes: CPS1
Study NCT01420081 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01420081 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT01420081 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT04348045 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00901797 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study NCT02915744 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT03806582 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06181188 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01227512 — Surrogate Endpoint (SUR): Serum sodium
Study NCT00170079 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT02873013 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT00647114 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03817073 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT00533650 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02630368 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04034940 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study NCT00695942 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03568422 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study NCT03568422 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03279432 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT03279432 — Predictive Biomarker (PRD): LRP2 mRNA
Genes: LRP2
Study NCT01428336 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT04410107 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04410107 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05798182 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05798182 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00973791 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01355796 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT01081808 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01081808 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03379727 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04539860 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00668590 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02736565 — Predictive Biomarker (PRD): FLI1 mRNA
Genes: FLI1
Study NCT03082014 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00473603 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04869033 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01806051 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study NCT01276314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02611258 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT02240381 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00049062 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02361528 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02361528 — Safety Biomarker (SAF): Human leucocyte antigen
Study NCT04403321 — Surrogate Endpoint (SUR): Hematologic response
Study NCT03918343 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study NCT02156427 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02471768 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04605575 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01753453 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT01753453 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01487005 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04353882 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study NCT00546091 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03298763 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT00098839 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT05329597 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT02691767 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT05063266 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00134381 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01158222 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00313196 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00313196 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02654236 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT00377559 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01762267 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00702494 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02307799 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01655381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01633346 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study NCT01633346 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT01633346 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study NCT01633346 — Predictive Biomarker (PRD): STAT5B mRNA
Genes: STAT5B
Study NCT03418558 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05188352 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04655911 — Predictive Biomarker (PRD): NAGLU mRNA
Genes: NAGLU; UFHSD1
Study NCT02178475 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03397992 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04122833 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1