TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21224421 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7878632 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18400731 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18400731 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12707129 — Surrogate Endpoint (SUR): Blood pressure
Study 1347965 — Surrogate Endpoint (SUR): Blood pressure
Study 3513530 — Surrogate Endpoint (SUR): Blood pressure
Study 28540570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27207543 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20497977 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 20497977 — Surrogate Endpoint (SUR): Blood pressure
Study 11056328 — Surrogate Endpoint (SUR): Bone mineral density
Study 11056328 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11056328 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8897562 — Surrogate Endpoint (SUR): Serum creatinine
Study 24798395 — Surrogate Endpoint (SUR): Blood pressure
Study 20200550 — Surrogate Endpoint (SUR): Blood pressure
Study 8576893 — Surrogate Endpoint (SUR): Blood pressure
Study 28594709 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19801363 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19801363 — Surrogate Endpoint (SUR): Blood pressure
Study 19281053 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15780108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15780108 — Surrogate Endpoint (SUR): Blood pressure
Study 9442775 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 238278 — Surrogate Endpoint (SUR): Blood pressure
Study 29681434 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 29681434 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 23560491 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 16773409 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16773409 — Surrogate Endpoint (SUR): Blood pressure
Study 16773409 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31148436 — Surrogate Endpoint (SUR): Blood pressure
Study 27035501 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 22361603 — Surrogate Endpoint (SUR): Blood pressure
Study 9797801 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9797801 — Surrogate Endpoint (SUR): Blood pressure
Study 9797801 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 7706943 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30647445 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 30647445 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 21685340 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 19212856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 1726005 — Surrogate Endpoint (SUR): Blood pressure
Study 30814387 — Safety Biomarker (SAF): Hyaluronic acid
Study 29396374 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12529346 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6407503 — Surrogate Endpoint (SUR): Blood pressure
Study 31416344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31416344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29895378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29895378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20800986 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 3889071 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 3889071 — Surrogate Endpoint (SUR): Probing pocket depth
Study 30607117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30607117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27501003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22728519 — Surrogate Endpoint (SUR): Bone mineral density
Study 22728519 — Surrogate Endpoint (SUR): Serum calcium
Study 16255010 — Surrogate Endpoint (SUR): Bone mineral density
Study 28937147 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24189763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24189763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16599830 — Safety Biomarker (SAF): Reactive oxygen species
Study 9284763 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27459273 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27459273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22646240 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11897445 — Surrogate Endpoint (SUR): Blood pressure
Study 11897445 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11897445 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7837151 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30595325 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 12944028 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12944028 — Surrogate Endpoint (SUR): Blood pressure
Study 10535435 — Surrogate Endpoint (SUR): Blood pressure
Study 6754508 — Surrogate Endpoint (SUR): Serum potassium
Study 20484446 — Surrogate Endpoint (SUR): Serum calcium
Study 3486112 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26695864 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26695864 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 26695864 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26695864 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 26695864 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 26695864 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26695864 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26695864 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22809999 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 18227541 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 9872190 — Surrogate Endpoint (SUR): Serum creatinine
Study 28508936 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 24962143 — Surrogate Endpoint (SUR): Blood pressure
Study 19254484 — Surrogate Endpoint (SUR): Blood pressure
Study 10989729 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28421299 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28421299 — Surrogate Endpoint (SUR): Serum potassium
Study 28421299 — Surrogate Endpoint (SUR): Serum calcium
Study 28421299 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 10914843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30541621 — Surrogate Endpoint (SUR): Blood pressure
Study 21284444 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 3115136 — Surrogate Endpoint (SUR): Blood pressure
Study 20306851 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 15749459 — Surrogate Endpoint (SUR): Blood pressure
Study 29130810 — Surrogate Endpoint (SUR): Serum creatinine
Study 15933926 — Surrogate Endpoint (SUR): Serum potassium
Study 15933926 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 28912054 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28912054 — Surrogate Endpoint (SUR): Blood pressure
Study 18537977 — Safety Biomarker (SAF): Human leucocyte antigen
Study 10894866 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30868672 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 24667440 — Predictive Biomarker (PRD): FCGR2A mRNA
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 24667440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31118140 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31118140 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 31118140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31118140 — Safety Biomarker (SAF): RAS pathway
Study 25955227 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25955227 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11591895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11591895 — Surrogate Endpoint (SUR): Serum creatinine
Study 2659954 — Surrogate Endpoint (SUR): Blood pressure
Study 22028623 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 9651568 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7543955 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25273886 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 26284539 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 8933780 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 8933780 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17485893 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17485893 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17485893 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15001191 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 15001191 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 15001191 — Surrogate Endpoint (SUR): Blood pressure
Study 9732338 — Surrogate Endpoint (SUR): Blood pressure
Study 9732338 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28086872 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28086872 — Surrogate Endpoint (SUR): Blood pressure
Study 28086872 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26111351 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26111351 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23424237 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23424237 — Surrogate Endpoint (SUR): Blood pressure
Study 8169417 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30400688 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 25302462 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25302462 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20297611 — Surrogate Endpoint (SUR): Blood pressure
Study 6987024 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 6987024 — Surrogate Endpoint (SUR): Blood pressure
Study 28409402 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28409402 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 28409402 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23638986 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 2813982 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 22460459 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 11890840 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11890840 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30325178 — Predictive Biomarker (PRD): Hormone receptor
Study 9138281 — Monitoring Biomarker (MOI): HBV DNA
Study 8184968 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8184968 — Surrogate Endpoint (SUR): Blood pressure
Study 29210921 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 21824325 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 21824325 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 21824325 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 21824325 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 18238788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12966542 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12966542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12966542 — Monitoring Biomarker (MOI): HBV DNA
Study 12966542 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3622555 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15667504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9675609 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8008712 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15282836 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 31364497 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28839340 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 24020450 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 21511217 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15480538 — Surrogate Endpoint (SUR): Blood pressure
Study 15480538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10227447 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 1591822 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1591822 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25912765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23747051 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 1299486 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 31364269 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 31364269 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28202270 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28202270 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28202270 — Surrogate Endpoint (SUR): Serum uric acid
Study 28202270 — Surrogate Endpoint (SUR): Blood pressure
Study 28202270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25305000 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19602614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17643582 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15022037 — Surrogate Endpoint (SUR): Bone mineral density
Study 9609132 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9609132 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26189560 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23659338 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27078022 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30342553 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24815889 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 16159570 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16159570 — Surrogate Endpoint (SUR): Blood pressure
Study 16159570 — Surrogate Endpoint (SUR): Serum creatinine
Study 2147599 — Surrogate Endpoint (SUR): Serum calcium
Study 22289549 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16432086 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15134181 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15134181 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 15134181 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 31102457 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 31102457 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 31102457 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 28077344 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25227729 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25227729 — Surrogate Endpoint (SUR): Blood pressure
Study 14551133 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 9240732 — Surrogate Endpoint (SUR): Bone mineral density
Study 10369728 — Surrogate Endpoint (SUR): Bone mineral density
Study 10369728 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 8658369 — Surrogate Endpoint (SUR): Blood pressure
Study 1867125 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30640204 — Surrogate Endpoint (SUR): Bone mineral density
Study 9305555 — Predictive Biomarker (PRD): GSC mRNA
Genes: GSC
Study 27120807 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 18845978 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18845978 — Safety Biomarker (SAF): BDNF
Study 22858449 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18952354 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 6088439 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23281860 — Surrogate Endpoint (SUR): Blood pressure
Study 16104914 — Surrogate Endpoint (SUR): Blood pressure
Study 31852422 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 31504106 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 23331949 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19861619 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9799030 — Surrogate Endpoint (SUR): Blood pressure
Study 26264702 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 26264702 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 26264702 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 1872460 — Surrogate Endpoint (SUR): Blood pressure
Study 28235529 — Surrogate Endpoint (SUR): Blood pressure
Study 20494961 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15849476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15849476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10604492 — Surrogate Endpoint (SUR): Blood pressure
Study 21606974 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9793807 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7648764 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20166406 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 23905228 — Surrogate Endpoint (SUR): Blood pressure
Study 30669147 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30669147 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 30669147 — Predictive Biomarker (PRD): FGFR4 mRNA
Genes: FGFR4; JTK2; TKF
Study 10235427 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10235427 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28320258 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28320258 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26184556 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16356192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15311008 — Surrogate Endpoint (SUR): Urinary oxalate
Study 9328950 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20498212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16360211 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 16360211 — Safety Biomarker (SAF): Hyaluronic acid
Study 9057957 — Surrogate Endpoint (SUR): Blood pressure
Study 2439823 — Surrogate Endpoint (SUR): Blood pressure
Study 29396603 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 21701685 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 15204043 — Surrogate Endpoint (SUR): Blood pressure
Study 15204043 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10742708 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28219804 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28219804 — Surrogate Endpoint (SUR): Blood pressure
Study 26174461 — Surrogate Endpoint (SUR): Blood pressure
Study 23446104 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 23446104 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 12923399 — Surrogate Endpoint (SUR): Blood pressure
Study 8587251 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8587251 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 29028930 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 22230384 — Safety Biomarker (SAF): MTHFR