TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31659977 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28555251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23499273 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21584955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10878147 — Surrogate Endpoint (SUR): Bone mineral density
Study 28275117 — Predictive Biomarker (PRD): EGFL7 mRNA
Genes: EGFL7; MEGF7; UNQ187/PRO1449
Study 28275117 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12725561 — Surrogate Endpoint (SUR): Blood pressure
Study 3690045 — Surrogate Endpoint (SUR): Blood pressure
Study 12721242 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 12721242 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19041012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10981173 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3119520 — Surrogate Endpoint (SUR): Blood pressure
Study 29035687 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29035687 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 20398563 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20398563 — Surrogate Endpoint (SUR): Blood pressure
Study 12027065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12027065 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 12027065 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1450310 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1450310 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 1450310 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 1450310 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 1450310 — Surrogate Endpoint (SUR): Blood pressure
Study 1450310 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26037427 — Surrogate Endpoint (SUR): Blood pressure
Study 22786751 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18678157 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 12463967 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 21179730 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 17666281 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 17666281 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18842166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18842166 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16740317 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14662525 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8993757 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 8993757 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 8993757 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8993757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8993757 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31202957 — Surrogate Endpoint (SUR): Blood pressure
Study 31202957 — Surrogate Endpoint (SUR): Serum potassium
Study 2150795 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 31905615 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22459389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22459389 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 18471628 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 17049890 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 3408211 — Surrogate Endpoint (SUR): Blood pressure
Study 18817909 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 29097444 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 24673650 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 22818151 — Predictive Biomarker (PRD): MDK mRNA
Genes: MDK; MK1; NEGF2
Study 19115219 — Monitoring Biomarker (MOI): HBV DNA
Study 24567366 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 12828801 — Surrogate Endpoint (SUR): Blood pressure
Study 8695241 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 1738412 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31607313 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29925916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20110052 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 808359 — Surrogate Endpoint (SUR): Blood pressure
Study 8629915 — Surrogate Endpoint (SUR): Blood pressure
Study 29167892 — Predictive Biomarker (PRD): Microsatellite instability
Study 18003795 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18003795 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 14980088 — Surrogate Endpoint (SUR): Blood pressure
Study 8393888 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8393888 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 24002623 — Surrogate Endpoint (SUR): Blood pressure
Study 24002623 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17073356 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29531764 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 27428073 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2661435 — Surrogate Endpoint (SUR): Blood pressure
Study 31422414 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 16114156 — Surrogate Endpoint (SUR): Blood pressure
Study 17293547 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 12080353 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12080353 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12080353 — Predictive Biomarker (PRD): TNC mRNA
Genes: TNC; HXB
Study 2573444 — Surrogate Endpoint (SUR): Blood pressure
Study 30625297 — Monitoring Biomarker (MOI): HBV DNA
Study 26486868 — Surrogate Endpoint (SUR): Blood pressure
Study 21402563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21402563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26251016 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17642144 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 11555104 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11555104 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 11522614 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 9632121 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7829401 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study 2826952 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20864405 — Predictive Biomarker (PRD): RHOBTB2 mRNA
Genes: RHOBTB2; DBC2; KIAA0717
Study 20864405 — Predictive Biomarker (PRD): CPT1C mRNA
Genes: CPT1C; CATL1
Study 20864405 — Predictive Biomarker (PRD): SOX8 mRNA
Genes: SOX8
Study 20864405 — Predictive Biomarker (PRD): ALOX12 mRNA
Genes: ALOX12; 12LO; LOG12
Study 20864405 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 20864405 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 20864405 — Predictive Biomarker (PRD): MYO5A mRNA
Genes: MYO5A; MYH12
Study 20864405 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 20864405 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor delta
Genes: PPARD
Study 20864405 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study 20864405 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 30187872 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30187872 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 22864036 — Surrogate Endpoint (SUR): Blood pressure
Study 26253869 — Predictive Biomarker (PRD): UMPS mRNA
Genes: UMPS; OK/SW-cl.21
Study 27680405 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 22386043 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18676075 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17705570 — Surrogate Endpoint (SUR): Blood pressure
Study 20691300 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 20691300 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18726564 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1677266 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 26712560 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24475026 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 12667322 — Surrogate Endpoint (SUR): Blood pressure
Study 9707191 — Surrogate Endpoint (SUR): Blood pressure
Study 7661873 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27722840 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23812272 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23812272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20151997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11007240 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 26251965 — Predictive Biomarker (PRD): IL13
Genes: P600; IL-13; ALRH; BHR1; MGC116786; MGC116788; MGC116789
Study 12392583 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20168099 — Surrogate Endpoint (SUR): Bone mineral density
Study 9389780 — Surrogate Endpoint (SUR): Bone mineral density
Study 9389780 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29618017 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 24216317 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 14563580 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28039902 — Monitoring Biomarker (MOI): HBV DNA
Study 26604652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7041522 — Surrogate Endpoint (SUR): Serum creatinine
Study 7041522 — Surrogate Endpoint (SUR): Serum calcium
Study 28372661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15292307 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 26251958 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16861405 — Surrogate Endpoint (SUR): Blood pressure
Study 10390546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28968167 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24690021 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19394661 — Surrogate Endpoint (SUR): Blood pressure
Study 19394661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15658652 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30623096 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19356075 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 19356075 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31037562 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25418187 — Predictive Biomarker (PRD): Liver iron
Study 14523786 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14523786 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7752906 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7752906 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7752906 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7011237 — Surrogate Endpoint (SUR): Serum potassium
Study 31129681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31129681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29697876 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27492510 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 20577923 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 11771856 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23602770 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8950732 — Surrogate Endpoint (SUR): Blood pressure
Study 6290228 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22382596 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 9921806 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 7573900 — Surrogate Endpoint (SUR): Blood pressure
Study 30620668 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30620668 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 24131674 — Surrogate Endpoint (SUR): Serum calcium
Study 7668036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7192617 — Surrogate Endpoint (SUR): Blood pressure
Study 28166324 — Surrogate Endpoint (SUR): Blood pressure
Study 14578410 — Surrogate Endpoint (SUR): Blood pressure
Study 9049040 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18463885 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 16612257 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16612257 — Surrogate Endpoint (SUR): Blood pressure
Study 10769011 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 10769011 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 3870921 — Surrogate Endpoint (SUR): Blood pressure
Study 25135997 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 25135997 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15924587 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15924587 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7956631 — Surrogate Endpoint (SUR): Blood pressure
Study 18573713 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 9100037 — Predictive Biomarker (PRD): ERF mRNA
Genes: ERF
Study 8299406 — Surrogate Endpoint (SUR): Serum calcium
Study 8299406 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 27267753 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 23492647 — Surrogate Endpoint (SUR): Blood pressure
Study 16957573 — Surrogate Endpoint (SUR): Blood pressure
Study 9024449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22169794 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 18684771 — Surrogate Endpoint (SUR): Blood pressure
Study 17313008 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 6388715 — Surrogate Endpoint (SUR): Blood pressure
Study 18797484 — Surrogate Endpoint (SUR): Blood pressure
Study 31261928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 27484437 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21627458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19755410 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19755410 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17995584 — Surrogate Endpoint (SUR): Serum creatinine
Study 21831508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21831508 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11788129 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11788129 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7882815 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7882815 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11083688 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29415891 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 29415891 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 26721228 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 25948720 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23589106 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18855824 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 14675918 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31524075 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17133211 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12940591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10698133 — Surrogate Endpoint (SUR): Blood pressure
Study 2875317 — Surrogate Endpoint (SUR): Blood pressure
Study 28024882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26744910 — Predictive Biomarker (PRD): MFF mRNA
Genes: MFF; C2orf33; AD030; AD033; GL004
Study 16277999 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16277999 — Surrogate Endpoint (SUR): Blood pressure
Study 8824694 — Surrogate Endpoint (SUR): Blood pressure
Study 28031053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28031053 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28031053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 14555269 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 25952818 — Safety Biomarker (SAF): Hyaluronic acid
Study 19118844 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 9236432 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29173997 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29173997 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 29173997 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 29173997 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24159564 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 26931279 — Surrogate Endpoint (SUR): Bone mineral density
Study 8948272 — Surrogate Endpoint (SUR): Bone mineral density
Study 31335587 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 31335587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25057173 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25057173 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 22173910 — Surrogate Endpoint (SUR): Blood pressure
Study 28866675 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28866675 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21816980 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 22879908 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 10905644 — Surrogate Endpoint (SUR): Blood pressure
Study 9140791 — Surrogate Endpoint (SUR): Blood pressure
Study 25795406 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 14555263 — Surrogate Endpoint (SUR): Bone mineral density
Study 31895884 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20551833 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20551833 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16007101 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14671611 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 27183343 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 11231393 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 6244920 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6244920 — Surrogate Endpoint (SUR): Blood pressure
Study 30389229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30389229 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30389229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30389229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2