TrialPanorama/TrialPanorama-database huggingface dataset:
Study 3056057 — Surrogate Endpoint (SUR): Serum uric acid
Study 3056057 — Surrogate Endpoint (SUR): Serum creatinine
Study 26647154 — Surrogate Endpoint (SUR): Blood pressure
Study 18712575 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2178930 — Surrogate Endpoint (SUR): Blood pressure
Study 29081307 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 29081307 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 25366684 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 17485023 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17485023 — Surrogate Endpoint (SUR): Blood pressure
Study 7669316 — Surrogate Endpoint (SUR): Blood pressure
Study 27565129 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21192153 — Surrogate Endpoint (SUR): Blood pressure
Study 17206296 — Surrogate Endpoint (SUR): Blood pressure
Study 1980201 — Surrogate Endpoint (SUR): Blood pressure
Study 31797035 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 27543440 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 27543440 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 2883214 — Surrogate Endpoint (SUR): Blood pressure
Study 26466857 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26466857 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8172793 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 2963523 — Surrogate Endpoint (SUR): Blood pressure
Study 20298418 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 28207537 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 15025216 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 11831591 — Surrogate Endpoint (SUR): Blood pressure
Study 31599225 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12479764 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12479764 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28453240 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23511357 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 8373973 — Surrogate Endpoint (SUR): Blood pressure
Study 27011304 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 22873565 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 22873565 — Predictive Biomarker (PRD): AIF1 mRNA
Genes: AIF1; G1; IBA1
Study 22873565 — Predictive Biomarker (PRD): HCG22 mRNA
Genes: HCG22; G2; PBMUCL2
Study 1690202 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 31272903 — Predictive Biomarker (PRD): MDC1 mRNA
Genes: MDC1; KIAA0170; NFBD1
Study 23742912 — Monitoring Biomarker (MOI): HBV DNA
Study 6805499 — Surrogate Endpoint (SUR): Serum calcium
Study 6805499 — Surrogate Endpoint (SUR): Serum creatinine
Study 6805499 — Surrogate Endpoint (SUR): Blood pressure
Study 24114400 — Surrogate Endpoint (SUR): Bone mineral density
Study 18265482 — Predictive Biomarker (PRD): Hormone receptor
Study 16885405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8213511 — Surrogate Endpoint (SUR): Blood pressure
Study 18403223 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 24584926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10866886 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10866886 — Surrogate Endpoint (SUR): Blood pressure
Study 8212201 — Surrogate Endpoint (SUR): Serum creatinine
Study 8212201 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3544690 — Surrogate Endpoint (SUR): Blood pressure
Study 3544690 — Surrogate Endpoint (SUR): Serum potassium
Study 29398422 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12450903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30806520 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 17100860 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1282588 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 1282588 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1282588 — Surrogate Endpoint (SUR): Blood pressure
Study 29762731 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18072822 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10721156 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10721156 — Surrogate Endpoint (SUR): Blood pressure
Study 2407885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30726946 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30726946 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30726946 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30726946 — Predictive Biomarker (PRD): Microsatellite instability
Study 25000151 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23251355 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 31447409 — Surrogate Endpoint (SUR): Bone mineral density
Study 27299475 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 26992609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26992609 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26992609 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21325465 — Surrogate Endpoint (SUR): Blood pressure
Study 21325465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1968319 — Surrogate Endpoint (SUR): Blood pressure
Study 29908043 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 29908043 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16134998 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10023789 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7775644 — Surrogate Endpoint (SUR): Serum testosterone
Study 2157231 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28321022 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8860111 — Surrogate Endpoint (SUR): Blood pressure
Study 24101043 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10806834 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29231608 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6994772 — Surrogate Endpoint (SUR): Blood pressure
Study 24498875 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24498875 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 22186099 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20560108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20560108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10361530 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11782871 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9840235 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 28705172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28705172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18826659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8663871 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6409208 — Surrogate Endpoint (SUR): Serum uric acid
Study 28679772 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9383806 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8031548 — Surrogate Endpoint (SUR): Blood pressure
Study 2902274 — Monitoring Biomarker (MOI): HBV DNA
Study 30755265 — Predictive Biomarker (PRD): CACNA1C mRNA
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 28199903 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 24292212 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 24892462 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22561774 — Surrogate Endpoint (SUR): Serum creatinine
Study 12390318 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12390318 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12390318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7539966 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2185673 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23868890 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 27128712 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9363971 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9363971 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9363971 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18630536 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12374459 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7854155 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 29273130 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 29273130 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 26562368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17484865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22914905 — Surrogate Endpoint (SUR): Blood pressure
Study 28424063 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15871195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15871195 — Safety Biomarker (SAF): IL-6 and IL-10
Study 25165165 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19465798 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19465798 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 15350001 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 7977479 — Surrogate Endpoint (SUR): Serum calcium
Study 2658526 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25748580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23582482 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11854938 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27402817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22147471 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 22147471 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20688622 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11045391 — Surrogate Endpoint (SUR): Blood pressure
Study 31120574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26538428 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 26538428 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 26538428 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 22685047 — Surrogate Endpoint (SUR): Blood pressure
Study 15937634 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15937634 — Surrogate Endpoint (SUR): Bone mineral density
Study 8969780 — Surrogate Endpoint (SUR): Blood pressure
Study 1370924 — Surrogate Endpoint (SUR): Blood pressure
Study 16420199 — Surrogate Endpoint (SUR): Bone mineral density
Study 3302924 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30001572 — Surrogate Endpoint (SUR): Bone mineral density
Study 27502847 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20038231 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 20038231 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 11230635 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27245553 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 27245553 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 453783 — Surrogate Endpoint (SUR): Blood pressure
Study 31658289 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25240532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17441321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17441321 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11504982 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9988364 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 9988364 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30982271 — Predictive Biomarker (PRD): FAM131A mRNA
Genes: FAM131A; C3orf40; UNQ715/PRO1378
Study 30982271 — Predictive Biomarker (PRD): CAPN15 mRNA
Genes: CAPN15; SOLH
Study 30982271 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 30982271 — Predictive Biomarker (PRD): SHISA5 mRNA
Genes: SHISA5; SCOTIN; PSEC0133
Study 30982271 — Predictive Biomarker (PRD): FGF13 mRNA
Genes: FGF13; FHF2
Study 30982271 — Predictive Biomarker (PRD): Tetranectin
Genes: CLEC3B; TNA
Study 30982271 — Predictive Biomarker (PRD): LILRB2 mRNA
Genes: LILRB2; ILT4; LIR2; MIR10
Study 16536664 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 11327445 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30742244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30742244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12887823 — Surrogate Endpoint (SUR): Blood pressure
Study 7555614 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7555614 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22849962 — Surrogate Endpoint (SUR): Bone mineral density
Study 15988786 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 11211570 — Surrogate Endpoint (SUR): Blood pressure
Study 30879358 — Surrogate Endpoint (SUR): Blood pressure
Study 26850040 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26850040 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26850040 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 24194532 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24194532 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20576665 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11943521 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11943521 — Surrogate Endpoint (SUR): Blood pressure
Study 10084367 — Surrogate Endpoint (SUR): Blood pressure
Study 2147859 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 458893 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19359647 — Surrogate Endpoint (SUR): Blood pressure
Study 12577435 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 27810028 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 12390820 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9661591 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 1972139 — Surrogate Endpoint (SUR): Blood pressure
Study 23841872 — Predictive Biomarker (PRD): BCL2A1 mRNA
Genes: BCL2A1; BCL2L5; BFL1; GRS; HBPA1
Study 15448429 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 31463484 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19756419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19756419 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2423799 — Surrogate Endpoint (SUR): Blood pressure
Study 17914351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22866290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 17406813 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 28938473 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22648467 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1351673 — Surrogate Endpoint (SUR): Blood pressure
Study 30469433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30469433 — Safety Biomarker (SAF): Reactive oxygen species
Study 19019358 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19019358 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19019358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19019358 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19019358 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12187499 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12187499 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6122483 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6122483 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6122483 — Surrogate Endpoint (SUR): Blood pressure
Study 25601538 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23900311 — Safety Biomarker (SAF): MTHFR
Study 1874212 — Surrogate Endpoint (SUR): Blood pressure
Study 31677181 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 26209863 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 15123224 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10510951 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31449168 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31449168 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31449168 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25121719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20139233 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7587005 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 26242122 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 26242122 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26242122 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 22966096 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16878257 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24973361 — Predictive Biomarker (PRD): ASXL2 mRNA
Genes: ASXL2; ASXH2; KIAA1685
Study 24973361 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 7767 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11579707 — Surrogate Endpoint (SUR): Bone mineral density
Study 26166166 — Surrogate Endpoint (SUR): Total kidney volume
Study 23214253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23214253 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23214253 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16710252 — Surrogate Endpoint (SUR): Blood pressure
Study 14567499 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10423075 — Surrogate Endpoint (SUR): Blood pressure
Study 1796409 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1796409 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11122727 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29412521 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26483047 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 18683781 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6510013 — Surrogate Endpoint (SUR): Blood pressure
Study 8637302 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 22245235 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20968113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2169701 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20395129 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 18356684 — Surrogate Endpoint (SUR): Blood pressure
Study 12839658 — Surrogate Endpoint (SUR): Blood pressure
Study 31717505 — Surrogate Endpoint (SUR): Blood pressure
Study 11798370 — Surrogate Endpoint (SUR): Serum creatinine
Study 1912739 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 7094972 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12915640 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 10555031 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 7044932 — Surrogate Endpoint (SUR): Blood pressure
Study 16923452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16923452 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16923452 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2565329 — Surrogate Endpoint (SUR): Serum potassium
Study 31757033 — Surrogate Endpoint (SUR): Blood pressure