TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05037396 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03125902 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04274738 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT04274738 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study NCT01070186 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01070186 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04197388 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00225784 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00225784 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02722265 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT02722265 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03917446 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01183468 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT04585334 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT02619032 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04687098 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04687098 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT02884492 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01124838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03886038 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01517113 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01471535 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00120185 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00120185 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03601598 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT01410981 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT01410981 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT04289259 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT02549417 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT02108392 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study NCT00095173 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03236935 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT03236935 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT04321837 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00480545 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04387045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04184921 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04184921 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01509443 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03837483 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03981003 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT01584427 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04780594 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00586820 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT00403689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02986854 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study NCT03009084 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02908165 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02908165 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03955484 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT03955484 — Safety Biomarker (SAF): BDNF
Study NCT01479465 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04629846 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04629846 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01741389 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00514592 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04795206 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study NCT00983905 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT00280683 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00661947 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03184285 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01169636 — Predictive Biomarker (PRD): HDAC1 mRNA
Genes: HDAC1; RPD3L1
Study NCT03660397 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03866239 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02579824 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT00072683 — Surrogate Endpoint (SUR): Serum sodium
Study NCT02418715 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT03485196 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT01329471 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT04418661 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01547117 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00002796 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01958918 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03871621 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02168283 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02778464 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT01772823 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01772823 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03637166 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02656849 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study NCT02656849 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT02656849 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCNE1 mRNA
Genes: CCNE1; CCNE
Study NCT01678794 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03080636 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01186731 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT01409122 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04394650 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT00336557 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02355444 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04830826 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01365468 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00417846 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03752242 — Predictive Biomarker (PRD): BMX mRNA
Genes: BMX
Study NCT00523744 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03959501 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00847197 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01098526 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00568698 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT02717741 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02149524 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00113581 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04105166 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00223704 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03584256 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02492698 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT02719314 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02606136 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02201602 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study NCT02372981 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT04450095 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03356795 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04096469 — Predictive Biomarker (PRD): CPTP mRNA
Genes: CPTP; GLTPD1
Study NCT04096469 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04096469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04096469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04096469 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04096469 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04096469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04096469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00031629 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06456086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06456086 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study NCT06456086 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT01006616 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study NCT00002336 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02668679 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study NCT02243787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02243787 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT02947841 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT04352335 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT00558675 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT01339650 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01339650 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT00083616 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02215200 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT00026182 — Safety Biomarker (SAF): Interleukin 12
Study NCT02735590 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03225976 — Safety Biomarker (SAF): Cytochrome c
Study NCT03225976 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT05138692 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04670679 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT01256957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03318861 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03779529 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT03779529 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01057251 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02136264 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04457258 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT02486419 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study NCT02486419 — Predictive Biomarker (PRD): CIDEA mRNA
Genes: CIDEA
Study NCT02486419 — Predictive Biomarker (PRD): PRDM16 mRNA
Genes: PRDM16; KIAA1675; MEL1; PFM13
Study NCT03122847 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03663335 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT02089438 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02089438 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03770052 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03324113 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04035330 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT00793078 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01208675 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT03884972 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT02156310 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02156310 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04736784 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00153101 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00080860 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT01531764 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01531764 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01097564 — Predictive Biomarker (PRD): COL4A1 mRNA
Genes: COL4A1
Study NCT00151645 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02634827 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02323542 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study NCT03499912 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT03499912 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT05972798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02495584 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02495584 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01281722 — Predictive Biomarker (PRD): ABCB5 mRNA
Genes: ABCB5
Study NCT01281722 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study NCT00027703 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03209908 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04689984 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00364611 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02365740 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT04217044 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT02862028 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02862028 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02599922 — Predictive Biomarker (PRD): CNGB3 mRNA
Genes: CNGB3
Study NCT00126386 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study NCT04932642 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04303247 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04303247 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT00340990 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01072682 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06502808 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT06502808 — Predictive Biomarker (PRD): GPX2 mRNA
Genes: GPX2
Study NCT06502808 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT06502808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06502808 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT06502808 — Safety Biomarker (SAF): Interleukin 12
Study NCT00453453 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00287534 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03737344 — Safety Biomarker (SAF): Interleukin 1
Study NCT02618512 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03699618 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00959127 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00357617 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02095639 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT00002875 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT00651261 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00528801 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01842191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03378596 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04354584 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04354584 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01644071 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study NCT05111743 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05111743 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00572936 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03096756 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT00950742 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02973854 — Predictive Biomarker (PRD): S1PR1 mRNA
Genes: S1PR1; CHEDG1; EDG1
Study NCT02195141 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01982175 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT04509635 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02095938 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02095938 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01772121 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT01545557 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00773747 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study NCT00098306 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT04922905 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04318600 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00703586 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT01953913 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01953913 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02759926 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT01070654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00940862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00985270 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study NCT00036257 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05684185 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00509405 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02781311 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT00330356 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01094275 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03615066 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02359227 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT01577472 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study NCT01050361 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02401945 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02055976 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02055976 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04748250 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00667667 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01897090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01897090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04372173 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04372173 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT03747523 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT00396734 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT03990142 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03040115 — Predictive Biomarker (PRD): FLCN mRNA
Genes: FLCN; BHD
Study NCT04084847 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01609010 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20