TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27026642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22554716 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12199627 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12199627 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30314508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30314508 — Surrogate Endpoint (SUR): Serum uric acid
Study 20977758 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 12171880 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9189964 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9189964 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 1975188 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1975188 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 1975188 — Surrogate Endpoint (SUR): Blood pressure
Study 20029520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8529334 — Surrogate Endpoint (SUR): Blood pressure
Study 8529334 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26460564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26460564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26460564 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20390342 — Predictive Biomarker (PRD): TNS4 mRNA
Genes: TNS4; CTEN; PP14434
Study 19641483 — Surrogate Endpoint (SUR): Serum potassium
Study 19641483 — Surrogate Endpoint (SUR): Blood pressure
Study 9768932 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2680271 — Surrogate Endpoint (SUR): Blood pressure
Study 804952 — Surrogate Endpoint (SUR): Blood pressure
Study 24308188 — Predictive Biomarker (PRD): ASPRV1 mRNA
Genes: ASPRV1; SASP
Study 29607580 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 19178514 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 24829362 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21988525 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 2007848 — Surrogate Endpoint (SUR): Serum potassium
Study 16371894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10334150 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 28670117 — Surrogate Endpoint (SUR): Blood pressure
Study 25623564 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 25623564 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16150917 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 8639012 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8639012 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31476782 — Surrogate Endpoint (SUR): Blood pressure
Study 28864708 — Surrogate Endpoint (SUR): Blood pressure
Study 23722974 — Predictive Biomarker (PRD): HRC mRNA
Genes: HRC; HCP
Study 10676820 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27688160 — Surrogate Endpoint (SUR): Blood pressure
Study 22897460 — Surrogate Endpoint (SUR): Blood pressure
Study 18574751 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2178298 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9519350 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18719791 — Surrogate Endpoint (SUR): Blood pressure
Study 16794490 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16794490 — Surrogate Endpoint (SUR): Blood pressure
Study 8267478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8267478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8267478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26168834 — Surrogate Endpoint (SUR): Blood pressure
Study 21266159 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16571907 — Predictive Biomarker (PRD): AWAT2 mRNA
Genes: AWAT2; DC4; DGAT2L4; MFAT; WS
Study 16571907 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 11369828 — Surrogate Endpoint (SUR): Blood pressure
Study 11369828 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3304371 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17651376 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 16551713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15194376 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 15194376 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 9424901 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18422802 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 18422802 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22614132 — Surrogate Endpoint (SUR): Blood pressure
Study 12645643 — Safety Biomarker (SAF): Reactive oxygen species
Study 12645643 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12645643 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9893928 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 28478583 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 16431893 — Surrogate Endpoint (SUR): Serum creatinine
Study 16431893 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16431893 — Surrogate Endpoint (SUR): Blood pressure
Study 6374098 — Surrogate Endpoint (SUR): Blood pressure
Study 3580942 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 16210415 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 16210415 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 28700473 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 30196270 — Surrogate Endpoint (SUR): Blood pressure
Study 15734255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15734255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15734255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15734255 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26119811 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26119811 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19356912 — Surrogate Endpoint (SUR): Blood pressure
Study 30458863 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23206333 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 16950473 — Surrogate Endpoint (SUR): Blood pressure
Study 16950473 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12875611 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12875611 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8026000 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29082651 — Monitoring Biomarker (MOI): HBV DNA
Study 25098924 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 15217654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15217654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15217654 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8625167 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2166654 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 22368796 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 15161791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15161791 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9550533 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30744430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30744430 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24345055 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 31368268 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 30488889 — Surrogate Endpoint (SUR): Blood pressure
Study 26969417 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24527853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24527853 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 11910714 — Surrogate Endpoint (SUR): Blood pressure
Study 26385396 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26385396 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24290532 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 1532319 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30521970 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12701778 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9372647 — Surrogate Endpoint (SUR): Serum creatinine
Study 3005774 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 30388714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24135322 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 24135322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24135322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24135322 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 21768544 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8398224 — Surrogate Endpoint (SUR): Blood pressure
Study 29383894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29383894 — Surrogate Endpoint (SUR): Blood pressure
Study 29383894 — Safety Biomarker (SAF): Interleukin 1
Study 22504188 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 16198887 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 31558478 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27382104 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 24777901 — Predictive Biomarker (PRD): PAMR1 mRNA
Genes: PAMR1; RAMP; FP938; UNQ699/PRO1344
Study 19718394 — Surrogate Endpoint (SUR): Bone mineral density
Study 15103313 — Surrogate Endpoint (SUR): Blood pressure
Study 17996996 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 7196467 — Surrogate Endpoint (SUR): Blood pressure
Study 21415174 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25337750 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20177974 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 4025172 — Surrogate Endpoint (SUR): Blood pressure
Study 12145004 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 31411695 — Surrogate Endpoint (SUR): Blood pressure
Study 19683638 — Surrogate Endpoint (SUR): Blood pressure
Study 12795239 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 12795239 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9578931 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29697291 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29697291 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 29697291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29697291 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18362422 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15383370 — Predictive Biomarker (PRD): MED10 mRNA
Genes: MED10; L6; TRG17; TRG20
Study 25588906 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 18532969 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28850367 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 10397541 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2197098 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2197098 — Surrogate Endpoint (SUR): Blood pressure
Study 23278375 — Predictive Biomarker (PRD): SLA mRNA
Genes: SLA; SLAP; SLAP1
Study 22607887 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22607887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22607887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24530651 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24530651 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 23208165 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12587520 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 8122728 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31421685 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31421685 — Surrogate Endpoint (SUR): Blood pressure
Study 15001966 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 2465710 — Surrogate Endpoint (SUR): Blood pressure
Study 31402434 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 31565753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31565753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16857835 — Predictive Biomarker (PRD): TGFA mRNA
Genes: TGFA
Study 2111292 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 19087327 — Surrogate Endpoint (SUR): Blood pressure
Study 10419815 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 7752174 — Surrogate Endpoint (SUR): Blood pressure
Study 7752174 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7752174 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7752174 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24037008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10202315 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 6116855 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 29226471 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 29226471 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 29226471 — Surrogate Endpoint (SUR): Blood pressure
Study 22231479 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 22231479 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19553088 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 8737760 — Surrogate Endpoint (SUR): Blood pressure
Study 23809512 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23809512 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 23809512 — Surrogate Endpoint (SUR): Blood pressure
Study 30244217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30244217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24871547 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 25350500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25350500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25350500 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17704347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17704347 — Safety Biomarker (SAF): Reactive oxygen species
Study 11943524 — Surrogate Endpoint (SUR): Blood pressure
Study 1188710 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 21934690 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 14753731 — Surrogate Endpoint (SUR): Bone mineral density
Study 14500804 — Surrogate Endpoint (SUR): Bone mineral density
Study 1381643 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 22914365 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15631537 — Surrogate Endpoint (SUR): Blood pressure
Study 31947529 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21525158 — Predictive Biomarker (PRD): GCKR mRNA
Genes: GCKR
Study 21525158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19038501 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9525985 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 8306218 — Surrogate Endpoint (SUR): Blood pressure
Study 2917588 — Surrogate Endpoint (SUR): Blood pressure
Study 31416698 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28884566 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 23154587 — Surrogate Endpoint (SUR): Blood pressure
Study 16681772 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16681772 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16681772 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 16681772 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22382876 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22382876 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20646560 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11372590 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 31161726 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 25935877 — Surrogate Endpoint (SUR): Blood pressure
Study 24283598 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19194214 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31071734 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 25465932 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 25465932 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25465932 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16799819 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22738442 — Surrogate Endpoint (SUR): Blood pressure
Study 2054279 — Surrogate Endpoint (SUR): Blood pressure
Study 25311554 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22931259 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20673857 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 18173917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15468166 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 15468166 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20943753 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 11554430 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1375019 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 25297058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17440522 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16837436 — Safety Biomarker (SAF): Interleukin 1
Study 16837436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19347726 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 10626094 — Surrogate Endpoint (SUR): Blood pressure
Study 23368423 — Surrogate Endpoint (SUR): Blood pressure
Study 23368423 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20417488 — Predictive Biomarker (PRD): Interleukin 4 receptor alpha
Genes: IL4R; IL4RA; 582J2.1
Study 20417488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17220608 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 27522312 — Surrogate Endpoint (SUR): Blood pressure
Study 24477514 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22710563 — Surrogate Endpoint (SUR): Blood pressure
Study 20695899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1