TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11210867 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11210867 — Safety Biomarker (SAF): Interleukin 12
Study 11210867 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 11783268 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2472994 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28440817 — Surrogate Endpoint (SUR): Blood pressure
Study 24607004 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31498783 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 26924599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19932779 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19932779 — Surrogate Endpoint (SUR): Blood pressure
Study 9669811 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 27225598 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17805093 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9678378 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9678378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9678378 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 31668393 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 31668393 — Predictive Biomarker (PRD): CISH mRNA
Genes: CISH; G18
Study 31668393 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 31668393 — Predictive Biomarker (PRD): CIDEC mRNA
Genes: CIDEC; FSP27
Study 31668393 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 31668393 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17583188 — Surrogate Endpoint (SUR): Blood pressure
Study 11174052 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 3577821 — Surrogate Endpoint (SUR): Blood pressure
Study 16635085 — Surrogate Endpoint (SUR): Serum potassium
Study 7692189 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16514812 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9625099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1331724 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24409075 — Predictive Biomarker (PRD): NDP mRNA
Genes: NDP; EVR2
Study 15331202 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15331202 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15331202 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 30656849 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 18547177 — Safety Biomarker (SAF): Hyaluronic acid
Study 9778135 — Predictive Biomarker (PRD): PALM mRNA
Genes: PALM; KIAA0270
Study 9778135 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28371433 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21295937 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 11502994 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25085406 — Surrogate Endpoint (SUR): Blood pressure
Study 25085406 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17919550 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10075964 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10075964 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 27004529 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25574984 — Surrogate Endpoint (SUR): Blood pressure
Study 18336747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15632669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15632669 — Safety Biomarker (SAF): Interleukin 1
Study 30817778 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 30817778 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23351826 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17463297 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9511777 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9511777 — Surrogate Endpoint (SUR): Blood pressure
Study 7372352 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7372352 — Surrogate Endpoint (SUR): Blood pressure
Study 31397121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31397121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22939034 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 7527508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7527508 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16951690 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 14755132 — Surrogate Endpoint (SUR): Blood pressure
Study 3333529 — Surrogate Endpoint (SUR): Blood pressure
Study 31641769 — Surrogate Endpoint (SUR): Blood pressure
Study 28758192 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 26888985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 24915873 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 24915873 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24915873 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18546536 — Surrogate Endpoint (SUR): Blood pressure
Study 6711955 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 30764736 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 30764736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30764736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30764736 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study 25011980 — Surrogate Endpoint (SUR): Blood pressure
Study 22127561 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22127561 — Safety Biomarker (SAF): BDNF
Study 31650795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21831967 — Surrogate Endpoint (SUR): Blood pressure
Study 21831967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18355137 — Surrogate Endpoint (SUR): Serum creatinine
Study 14747124 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3294350 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3294350 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30701811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30701811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20625290 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22954122 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 22954122 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10728949 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10728949 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1326339 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22753635 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8730885 — Surrogate Endpoint (SUR): Blood pressure
Study 1680996 — Surrogate Endpoint (SUR): Blood pressure
Study 26758574 — Surrogate Endpoint (SUR): Blood pressure
Study 26758574 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22613585 — Surrogate Endpoint (SUR): Serum potassium
Study 10391361 — Surrogate Endpoint (SUR): Blood pressure
Study 28738939 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 22922245 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 18716800 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17698729 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17698729 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16307708 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16307708 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9535410 — Surrogate Endpoint (SUR): Blood pressure
Study 8562040 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31196131 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31196131 — Surrogate Endpoint (SUR): Serum creatinine
Study 29497091 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 29497091 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29497091 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 18241919 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8880364 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 24512193 — Surrogate Endpoint (SUR): Blood pressure
Study 24512193 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21045083 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 11873239 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30586726 — Surrogate Endpoint (SUR): Serum creatinine
Study 30586726 — Surrogate Endpoint (SUR): Blood pressure
Study 25654585 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25654585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25654585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18436293 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18436293 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 3293417 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24894197 — Predictive Biomarker (PRD): NKX3-1 mRNA
Genes: NKX3-1; NKX3.1; NKX3A
Study 25820017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20445570 — Surrogate Endpoint (SUR): Blood pressure
Study 6309436 — Surrogate Endpoint (SUR): Blood pressure
Study 7674236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21095491 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15705086 — Predictive Biomarker (PRD): HMBS mRNA
Genes: HMBS; PBGD; UPS
Study 1421975 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 29916560 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24355874 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 20398558 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 15673383 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 24297792 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 18321744 — Surrogate Endpoint (SUR): Serum potassium
Study 18321744 — Surrogate Endpoint (SUR): Blood pressure
Study 8725415 — Surrogate Endpoint (SUR): Blood pressure
Study 24947808 — Surrogate Endpoint (SUR): Blood pressure
Study 21157477 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15174010 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 9555659 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 2102133 — Surrogate Endpoint (SUR): Blood pressure
Study 16929706 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 7041324 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 22423956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22423956 — Safety Biomarker (SAF): IL-6 and IL-10
Study 28799413 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26857924 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26857924 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24556231 — Surrogate Endpoint (SUR): Serum creatinine
Study 24556231 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23218935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23218935 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23218935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23218935 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20824678 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8732628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24524399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24524399 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24524399 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19084393 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 17403312 — Surrogate Endpoint (SUR): Blood pressure
Study 22915172 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10992176 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10992176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22993930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22993930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9085945 — Surrogate Endpoint (SUR): Blood pressure
Study 30292891 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 30292891 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25390874 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19224163 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 22248659 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 22248659 — Predictive Biomarker (PRD): IFNL3
Genes: IL-28B; IL28C
Study 12798444 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21461372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17390549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17390549 — Surrogate Endpoint (SUR): Blood pressure
Study 8508863 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8508863 — Surrogate Endpoint (SUR): Blood pressure
Study 25956282 — Surrogate Endpoint (SUR): Bone mineral density
Study 19550428 — Surrogate Endpoint (SUR): Blood pressure
Study 9495509 — Surrogate Endpoint (SUR): Bone mineral density
Study 29894705 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 29894705 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29894705 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 29894705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29894705 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18492265 — Surrogate Endpoint (SUR): Blood pressure
Study 14585550 — Surrogate Endpoint (SUR): Blood pressure
Study 24507870 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 14871462 — Surrogate Endpoint (SUR): Blood pressure
Study 27872156 — Surrogate Endpoint (SUR): Blood pressure
Study 1415368 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 29599348 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8835112 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8835112 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8835112 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 23597114 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21567350 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16645967 — Surrogate Endpoint (SUR): Serum creatinine
Study 8983088 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 22581822 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11368133 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 29084330 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 12043767 — Surrogate Endpoint (SUR): Bone mineral density
Study 7861490 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 2024742 — Surrogate Endpoint (SUR): Blood pressure
Study 15518296 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 25549549 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 23385630 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23385630 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21467832 — Surrogate Endpoint (SUR): Blood pressure
Study 8682263 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 27003305 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23760362 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18519778 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 18519778 — Surrogate Endpoint (SUR): Serum creatinine
Study 18519778 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7496122 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 1828543 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1828543 — Surrogate Endpoint (SUR): Blood pressure
Study 7317896 — Surrogate Endpoint (SUR): Blood pressure
Study 26189231 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 26189231 — Surrogate Endpoint (SUR): Blood pressure
Study 20938783 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 19225530 — Surrogate Endpoint (SUR): Blood pressure
Study 19225530 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9431479 — Surrogate Endpoint (SUR): Blood pressure
Study 9431479 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7634748 — Surrogate Endpoint (SUR): Blood pressure
Study 26572698 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 25092108 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25092108 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15135267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19841860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19841860 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17650792 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 17650792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17650792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15618250 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15618250 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31083704 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21059830 — Surrogate Endpoint (SUR): Blood pressure
Study 9743397 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 28166784 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28166784 — Surrogate Endpoint (SUR): Blood pressure
Study 1457115 — Surrogate Endpoint (SUR): Blood pressure
Study 20735782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18370567 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31683114 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 8342319 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 3578940 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 18206891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15531493 — Surrogate Endpoint (SUR): Serum testosterone
Study 28269765 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21419556 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 8416021 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP