TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19889807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16952782 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16952782 — Surrogate Endpoint (SUR): Serum creatinine
Study 8861666 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25475196 — Surrogate Endpoint (SUR): Serum creatinine
Study 23268365 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19931080 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 19931080 — Surrogate Endpoint (SUR): Blood pressure
Study 19931080 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12401731 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12401731 — Surrogate Endpoint (SUR): Blood pressure
Study 29273027 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29273027 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19448381 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17854445 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 2142576 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 489921 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 28090798 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 20945090 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19756164 — Surrogate Endpoint (SUR): Blood pressure
Study 14667741 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10826311 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24732441 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20074348 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18175773 — Surrogate Endpoint (SUR): Blood pressure
Study 28039406 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28039406 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8728346 — Surrogate Endpoint (SUR): Blood pressure
Study 1996576 — Predictive Biomarker (PRD): RAPH1 mRNA
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 10202876 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10202876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 393356 — Surrogate Endpoint (SUR): Blood pressure
Study 22092168 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22092168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18825612 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 18825612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18825612 — Surrogate Endpoint (SUR): Blood pressure
Study 11587994 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3294067 — Surrogate Endpoint (SUR): Blood pressure
Study 28134562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28134562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28977202 — Surrogate Endpoint (SUR): Blood pressure
Study 21848706 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17270317 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 15073101 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 7930987 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29544801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29544801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29544801 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29544801 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20535948 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14636098 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 8621870 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3085131 — Surrogate Endpoint (SUR): Blood pressure
Study 15802340 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7669310 — Surrogate Endpoint (SUR): Blood pressure
Study 31603245 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31562715 — Surrogate Endpoint (SUR): Serum creatinine
Study 22045826 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17986292 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 7994666 — Surrogate Endpoint (SUR): Blood pressure
Study 197446 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 197446 — Surrogate Endpoint (SUR): Blood pressure
Study 18080768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10671908 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10671908 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8227897 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 24366547 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24366547 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22241678 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 17592099 — Predictive Biomarker (PRD): ATIC mRNA
Genes: ATIC; PURH; OK/SW-cl.86
Study 17592099 — Surrogate Endpoint (SUR): Blood pressure
Study 21157170 — Surrogate Endpoint (SUR): Blood pressure
Study 12011822 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31491873 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25466242 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 25466242 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25466242 — Surrogate Endpoint (SUR): Serum potassium
Study 14992907 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14992907 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8064171 — Surrogate Endpoint (SUR): Blood pressure
Study 8570343 — Surrogate Endpoint (SUR): Blood pressure
Study 2203397 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28093815 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 21285160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21285160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19965037 — Surrogate Endpoint (SUR): Blood pressure
Study 23860964 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 8147544 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29308522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29308522 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 23035844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23035844 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9108859 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9108859 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 24972190 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 8290177 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28095544 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 17047492 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17047492 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 17047492 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17047492 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 17047492 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9292758 — Surrogate Endpoint (SUR): Blood pressure
Study 8971958 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 8971958 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 8971958 — Surrogate Endpoint (SUR): Bone mineral density
Study 19395184 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 15023617 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15023617 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1534476 — Surrogate Endpoint (SUR): Bone mineral density
Study 29869078 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 29193126 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23160722 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 23160722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18308250 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 16219350 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 21498114 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 17711595 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 9821565 — Surrogate Endpoint (SUR): Serum sodium
Study 28377173 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15331203 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12003104 — Surrogate Endpoint (SUR): Bone mineral density
Study 7616989 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2911965 — Surrogate Endpoint (SUR): Blood pressure
Study 356719 — Surrogate Endpoint (SUR): Blood pressure
Study 31769875 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27194393 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 25730652 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25730652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25730652 — Safety Biomarker (SAF): BDNF
Study 22863562 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 12064363 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12064363 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12064363 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9800936 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9800936 — Surrogate Endpoint (SUR): Blood pressure
Study 23757474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23757474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19933596 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12679163 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12225612 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25134853 — Surrogate Endpoint (SUR): Blood pressure
Study 22987692 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 17590199 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15384026 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15384026 — Surrogate Endpoint (SUR): Blood pressure
Study 15384026 — Surrogate Endpoint (SUR): Serum potassium
Study 29050464 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 26004768 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26004768 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26004768 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 26004768 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 26004768 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 26004768 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18489937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18489937 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8817983 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1450043 — Surrogate Endpoint (SUR): Serum calcium
Study 1450043 — Surrogate Endpoint (SUR): Serum creatinine
Study 23698186 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 23698186 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 23698186 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15257185 — Surrogate Endpoint (SUR): Blood pressure
Study 2507028 — Surrogate Endpoint (SUR): Blood pressure
Study 2507028 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2507028 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26048319 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10102792 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 10102792 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10102792 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10102792 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 7775629 — Surrogate Endpoint (SUR): Blood pressure
Study 7775629 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7775629 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25268386 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25268386 — Surrogate Endpoint (SUR): Blood pressure
Study 16875158 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 16875158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16875158 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11910660 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 6800809 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9094048 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29226862 — Surrogate Endpoint (SUR): Blood pressure
Study 22499458 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12420568 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 10516750 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 10516750 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 1674589 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24193163 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8783689 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26836927 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22792314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22792314 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 22792314 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19910336 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9485067 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 9485067 — Safety Biomarker (SAF): DRD2
Study 2404477 — Surrogate Endpoint (SUR): Blood pressure
Study 31004357 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 22559839 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 17855695 — Pharmacodynamic Biomarker (PDY): Bcl-2 to Bax
Study 10225541 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 3291526 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21259277 — Surrogate Endpoint (SUR): Blood pressure
Study 30710258 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30710258 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22223702 — Safety Biomarker (SAF): Reactive oxygen species
Study 22223702 — Surrogate Endpoint (SUR): Serum testosterone
Study 21073267 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9657565 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 935199 — Surrogate Endpoint (SUR): Blood pressure
Study 31951323 — Surrogate Endpoint (SUR): Blood pressure
Study 28213743 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26531066 — Monitoring Biomarker (MOI): HBV DNA
Study 16532442 — Safety Biomarker (SAF): Hyaluronic acid
Study 31560220 — Surrogate Endpoint (SUR): Blood pressure
Study 18288492 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18288492 — Surrogate Endpoint (SUR): Blood pressure
Study 16221935 — Surrogate Endpoint (SUR): Blood pressure
Study 16221935 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7698137 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 2455126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 17141245 — Surrogate Endpoint (SUR): Blood pressure
Study 12076293 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9618627 — Surrogate Endpoint (SUR): Blood pressure
Study 31302707 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22818896 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24750327 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22134600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 19554089 — Surrogate Endpoint (SUR): Serum creatinine
Study 15631968 — Surrogate Endpoint (SUR): Blood pressure
Study 7962332 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22916805 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 22916805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15914307 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 31549899 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28975432 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 25934631 — Surrogate Endpoint (SUR): Blood pressure
Study 21729686 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study 9077371 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 26290867 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8780944 — Predictive Biomarker (PRD): TEP1 mRNA
Genes: TEP1; TLP1; TP1
Study 8780944 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 8780944 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 1623900 — Surrogate Endpoint (SUR): Blood pressure
Study 6597721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 2782269 — Surrogate Endpoint (SUR): Blood pressure
Study 28422861 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11469927 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9207358 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9207358 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 3304028 — Surrogate Endpoint (SUR): Blood pressure
Study 22732263 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22732263 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 22732263 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31960398 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31960398 — Surrogate Endpoint (SUR): Blood pressure
Study 31960398 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24548627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12893845 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10821873 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 22198338 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 17394651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26494370 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21411800 — Surrogate Endpoint (SUR): Serum sodium
Study 19643834 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3182163 — Surrogate Endpoint (SUR): Blood pressure
Study 31806881 — Predictive Biomarker (PRD): OPRK1 mRNA
Genes: OPRK1; OPRK
Study 31806881 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 14675858 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14598357 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 14598357 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14598357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14598357 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2746644 — Surrogate Endpoint (SUR): Blood pressure
Study 28685283 — Surrogate Endpoint (SUR): Bone mineral density
Study 25909333 — Surrogate Endpoint (SUR): Blood pressure
Study 31126960 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26442399 — Surrogate Endpoint (SUR): Blood pressure
Study 3792081 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 3792081 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28507187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26778524 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein