TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12904684 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12904684 — Surrogate Endpoint (SUR): Blood pressure
Study 12904684 — Surrogate Endpoint (SUR): Serum uric acid
Study 12904684 — Surrogate Endpoint (SUR): Serum potassium
Study 8872690 — Surrogate Endpoint (SUR): Blood pressure
Study 6096626 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21695666 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Growth/differentiation factor 8
Genes: MSTN; GDF8
Study 21695666 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 9269694 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9269694 — Surrogate Endpoint (SUR): Blood pressure
Study 23747646 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20032102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14529892 — Surrogate Endpoint (SUR): Serum calcium
Study 14529892 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 10759886 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 6712858 — Surrogate Endpoint (SUR): Blood pressure
Study 24246820 — Surrogate Endpoint (SUR): Blood pressure
Study 23291020 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 24393346 — Surrogate Endpoint (SUR): Blood pressure
Study 8703648 — Surrogate Endpoint (SUR): Blood pressure
Study 30001469 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 10648337 — Surrogate Endpoint (SUR): Blood pressure
Study 1737074 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 27027655 — Surrogate Endpoint (SUR): Bone mineral density
Study 23990605 — Surrogate Endpoint (SUR): Blood pressure
Study 23990605 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19665818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25716730 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 25716730 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 25716730 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 10539815 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10539815 — Surrogate Endpoint (SUR): Serum creatinine
Study 10539815 — Surrogate Endpoint (SUR): Blood pressure
Study 6629289 — Surrogate Endpoint (SUR): Blood pressure
Study 23525797 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 23525797 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-34a
Genes: MIR34A
Study 19698011 — Surrogate Endpoint (SUR): Blood pressure
Study 19698011 — Surrogate Endpoint (SUR): Serum creatinine
Study 31178422 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22336903 — Surrogate Endpoint (SUR): Blood pressure
Study 22336903 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22132138 — Surrogate Endpoint (SUR): Blood pressure
Study 18654005 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6322207 — Surrogate Endpoint (SUR): Blood pressure
Study 22788925 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23426275 — Surrogate Endpoint (SUR): Blood pressure
Study 23371457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23371457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23371457 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23371457 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18978640 — Surrogate Endpoint (SUR): Blood pressure
Study 10923530 — Surrogate Endpoint (SUR): Blood pressure
Study 21176950 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 21176950 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 11068974 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 25665607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9737283 — Surrogate Endpoint (SUR): Blood pressure
Study 8339858 — Surrogate Endpoint (SUR): Blood pressure
Study 3522040 — Surrogate Endpoint (SUR): Blood pressure
Study 26992038 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26992038 — Safety Biomarker (SAF): BDNF
Study 22858078 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28634972 — Surrogate Endpoint (SUR): Blood pressure
Study 22277140 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22277140 — Surrogate Endpoint (SUR): Blood pressure
Study 16299322 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 30975673 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 26968970 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22820612 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22820612 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19561150 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 31279749 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 25616646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20550020 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 18086798 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 12851519 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26967236 — Surrogate Endpoint (SUR): Blood pressure
Study 24112099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22313522 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 22313522 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 22313522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19962805 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 9796839 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30832554 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19522571 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 15793365 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20848367 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 7650167 — Predictive Biomarker (PRD): RNPC3 mRNA
Genes: RNPC3; KIAA1839; RBM40; RNP; SNRNP65
Study 27457964 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20133511 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 15034644 — Surrogate Endpoint (SUR): Bone mineral density
Study 11399694 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29771077 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 26503843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26503843 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22144668 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 16781228 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11773209 — Surrogate Endpoint (SUR): Blood pressure
Study 25455003 — Surrogate Endpoint (SUR): Blood pressure
Study 22520621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22520621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22520621 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22520621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22520621 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22520621 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22520621 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17544870 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 11438377 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30783676 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 21289258 — Surrogate Endpoint (SUR): Bone mineral density
Study 30928413 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 19114687 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 16988209 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10835090 — Surrogate Endpoint (SUR): Blood pressure
Study 786684 — Surrogate Endpoint (SUR): Blood pressure
Study 11211199 — Surrogate Endpoint (SUR): Serum creatinine
Study 8592965 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8592965 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27330157 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 27330157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17493468 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 8882469 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 31200828 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 31200828 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 24197291 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9797624 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 27771748 — Predictive Biomarker (PRD): Cadherin-13
Genes: CDH13; CDHH
Study 23371976 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21330401 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 9863091 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2888421 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16358378 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10216904 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19619920 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 15598677 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 17235418 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17235418 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study 23147277 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12610743 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8934377 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8934377 — Surrogate Endpoint (SUR): Blood pressure
Study 24968576 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 24968576 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19472126 — Surrogate Endpoint (SUR): Blood pressure
Study 15492149 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15492149 — Surrogate Endpoint (SUR): Blood pressure
Study 14679785 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 15235386 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31578141 — Predictive Biomarker (PRD): PRCC mRNA
Genes: PRCC; TPRC
Study 20652398 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30925360 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 21372609 — Surrogate Endpoint (SUR): Blood pressure
Study 15174909 — Surrogate Endpoint (SUR): Blood pressure
Study 2510877 — Surrogate Endpoint (SUR): Blood pressure
Study 24922652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 354732 — Surrogate Endpoint (SUR): Serum calcium
Study 25573317 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 25573317 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25573317 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18823458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18823458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10349036 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 1958601 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1958601 — Surrogate Endpoint (SUR): Blood pressure
Study 30721294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25070687 — Surrogate Endpoint (SUR): Serum creatinine
Study 19095219 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 16817651 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 1649683 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25724655 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25724655 — Surrogate Endpoint (SUR): Blood pressure
Study 19466447 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21095149 — Surrogate Endpoint (SUR): Serum calcium
Study 11027909 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 30523750 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 30523750 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 7746058 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23791061 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17991875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17991875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11153971 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 215338 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28745354 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28745354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28745354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28745354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24345171 — Predictive Biomarker (PRD): PCSK7 mRNA
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 10681768 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7716842 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23993864 — Predictive Biomarker (PRD): GNL3 mRNA
Genes: GNL3; E2IG3; NS
Study 17386321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17386321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17386321 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 15305403 — Predictive Biomarker (PRD): Hormone receptor
Study 11465583 — Surrogate Endpoint (SUR): Blood pressure
Study 2006994 — Surrogate Endpoint (SUR): Blood pressure
Study 17177902 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10823761 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10823761 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27270858 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27270858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27270858 — Safety Biomarker (SAF): BDNF
Study 22578793 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 15774531 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 8708885 — Predictive Biomarker (PRD): IVL mRNA
Genes: IVL
Study 1824799 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 15918057 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15918057 — Surrogate Endpoint (SUR): Blood pressure
Study 12044859 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25978942 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 23200117 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 20735795 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 18844761 — Surrogate Endpoint (SUR): Blood pressure
Study 26534729 — Surrogate Endpoint (SUR): Blood pressure
Study 9871862 — Surrogate Endpoint (SUR): Blood pressure
Study 27941393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17882140 — Surrogate Endpoint (SUR): Blood pressure
Study 15630270 — Surrogate Endpoint (SUR): Blood pressure
Study 9203227 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7898091 — Surrogate Endpoint (SUR): Blood pressure
Study 31462406 — Surrogate Endpoint (SUR): Blood pressure
Study 16647634 — Surrogate Endpoint (SUR): Bone mineral density
Study 10748312 — Surrogate Endpoint (SUR): Blood pressure
Study 8761899 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8761899 — Surrogate Endpoint (SUR): Blood pressure
Study 24953794 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 22180589 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 19904250 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10758799 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 8835706 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8835706 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29519353 — Surrogate Endpoint (SUR): Serum calcium
Study 16181528 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 16181528 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 14616429 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 9282610 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 1658591 — Predictive Biomarker (PRD): ALPK1 mRNA
Genes: ALPK1; KIAA1527; LAK
Study 23566246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23566246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10047932 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 7140397 — Surrogate Endpoint (SUR): Blood pressure
Study 30860474 — Monitoring Biomarker (MOI): HBV DNA
Study 15968652 — Predictive Biomarker (PRD): Liver iron
Study 6461916 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23565943 — Surrogate Endpoint (SUR): Blood pressure
Study 16403616 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3890307 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 31145885 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 30307302 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 27028914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27028914 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 27028914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27028914 — Surrogate Endpoint (SUR): Serum creatinine
Study 27028914 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30333337 — Surrogate Endpoint (SUR): Serum creatinine
Study 24347384 — Surrogate Endpoint (SUR): Blood pressure
Study 17587751 — Surrogate Endpoint (SUR): Blood pressure
Study 23662176 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 23662176 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21496284 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21496284 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15329203 — Monitoring Biomarker (MOI): HBV DNA
Study 9195505 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2878275 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26709136 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26709136 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26709136 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 26709136 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 21106941 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 21106941 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HSD3B1 mRNA
Genes: HSD3B1; 3BH; HSDB3A
Study 21106941 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 21106941 — Predictive Biomarker (PRD): ADD3 mRNA
Genes: ADD3; ADDL
Study 15811208 — Surrogate Endpoint (SUR): Bone mineral density
Study 12432670 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28556775 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 11719353 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7968073 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7968073 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 4623748 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 25214516 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25214516 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30202998 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23438670 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23438670 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23438670 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 1770067 — Surrogate Endpoint (SUR): Serum creatinine
Study 18560239 — Predictive Biomarker (PRD): PC mRNA
Genes: PC