TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17124558 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12510010 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12510010 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12510010 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 30383646 — Surrogate Endpoint (SUR): Blood pressure
Study 10065691 — Safety Biomarker (SAF): DRD2
Study 31483000 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19042026 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 19057518 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 19057518 — Surrogate Endpoint (SUR): Blood pressure
Study 19057518 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7655766 — Surrogate Endpoint (SUR): Blood pressure
Study 31862764 — Surrogate Endpoint (SUR): Blood pressure
Study 29773696 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28148500 — Surrogate Endpoint (SUR): Bone mineral density
Study 25445634 — Surrogate Endpoint (SUR): Blood pressure
Study 17898366 — Surrogate Endpoint (SUR): Blood pressure
Study 15281537 — Surrogate Endpoint (SUR): Blood pressure
Study 16169869 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 16169869 — Surrogate Endpoint (SUR): Blood pressure
Study 14690787 — Safety Biomarker (SAF): Reactive oxygen species
Study 8959286 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 26184491 — Surrogate Endpoint (SUR): Serum calcium
Study 26184491 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23738530 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 11055468 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11055468 — Surrogate Endpoint (SUR): Blood pressure
Study 9495994 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9495994 — Surrogate Endpoint (SUR): Blood pressure
Study 2873740 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19143675 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 16397514 — Surrogate Endpoint (SUR): Blood pressure
Study 24021709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24021709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24021709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24021709 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9427904 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30587148 — Surrogate Endpoint (SUR): Bone mineral density
Study 12351469 — Surrogate Endpoint (SUR): Blood pressure
Study 31443789 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 14513291 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 27417288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27417288 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 22196131 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17407159 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 12511851 — Predictive Biomarker (PRD): Hormone receptor
Study 535845 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30670737 — Surrogate Endpoint (SUR): Blood pressure
Study 30670737 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30670737 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25001663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25001663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25001663 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 25001663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25001663 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18805589 — Surrogate Endpoint (SUR): Blood pressure
Study 12411657 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 12411657 — Surrogate Endpoint (SUR): Blood pressure
Study 20175802 — Predictive Biomarker (PRD): SLC35A2 mRNA
Genes: SLC35A2; UGALT; UGT; UGTL
Study 15374773 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15374773 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15374773 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15117561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15117561 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15117561 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28027521 — Predictive Biomarker (PRD): IRF7 mRNA
Genes: IRF7
Study 19073361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19073361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15078732 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1234497 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16425428 — Monitoring Biomarker (MOI): HBV DNA
Study 11756059 — Safety Biomarker (SAF): Glycerol backbone
Study 9526817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26238111 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24145706 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16939542 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8628460 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 29908670 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 29908670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29908670 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 19148430 — Surrogate Endpoint (SUR): Blood pressure
Study 10486678 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10486678 — Surrogate Endpoint (SUR): Blood pressure
Study 7762497 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2086672 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 2086672 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30982177 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 23844756 — Surrogate Endpoint (SUR): Blood pressure
Study 26578370 — Surrogate Endpoint (SUR): Bone mineral density
Study 1634641 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1634641 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22643160 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 15110397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15110397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15110397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2643863 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2643863 — Surrogate Endpoint (SUR): Blood pressure
Study 2643863 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29203734 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 29203734 — Surrogate Endpoint (SUR): Blood pressure
Study 18031595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18031595 — Surrogate Endpoint (SUR): Blood pressure
Study 10447899 — Surrogate Endpoint (SUR): Blood pressure
Study 31680138 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 30339627 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 30339627 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 18287375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3971390 — Surrogate Endpoint (SUR): Blood pressure
Study 22248352 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9121997 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 1655262 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17342417 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17342417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17342417 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9479684 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9479684 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 9479684 — Surrogate Endpoint (SUR): Blood pressure
Study 31523014 — Surrogate Endpoint (SUR): Blood pressure
Study 18728933 — Surrogate Endpoint (SUR): Blood pressure
Study 8292466 — Surrogate Endpoint (SUR): Blood pressure
Study 30660609 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 30660609 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 21663652 — Surrogate Endpoint (SUR): Blood pressure
Study 14618196 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23265076 — Surrogate Endpoint (SUR): Blood pressure
Study 7978185 — Surrogate Endpoint (SUR): Blood pressure
Study 26031566 — Surrogate Endpoint (SUR): Blood pressure
Study 8927880 — Surrogate Endpoint (SUR): Blood pressure
Study 20396715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31164288 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 21732833 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19467054 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 8336198 — Surrogate Endpoint (SUR): Serum calcium
Study 31614946 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 31614946 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31614946 — Surrogate Endpoint (SUR): Blood pressure
Study 19649245 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 10100071 — Surrogate Endpoint (SUR): Blood pressure
Study 8738670 — Surrogate Endpoint (SUR): Blood pressure
Study 12742010 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3903788 — Surrogate Endpoint (SUR): Blood pressure
Study 11413075 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18056743 — Surrogate Endpoint (SUR): Serum creatinine
Study 8704119 — Surrogate Endpoint (SUR): Blood pressure
Study 15717259 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27440084 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 24446062 — Surrogate Endpoint (SUR): Blood pressure
Study 20561282 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 15619278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12645861 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12645861 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31641007 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31641007 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30826759 — Surrogate Endpoint (SUR): Blood pressure
Study 21617138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19331721 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14761878 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 14761878 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 14761878 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 28334510 — Surrogate Endpoint (SUR): Serum testosterone
Study 21144724 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10712354 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 3739595 — Surrogate Endpoint (SUR): Blood pressure
Study 30482633 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27168434 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 18508321 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8517437 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28992314 — Surrogate Endpoint (SUR): Blood pressure
Study 16804391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12792351 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12792351 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11529850 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26161483 — Surrogate Endpoint (SUR): Blood pressure
Study 1452528 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 29983350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29983350 — Predictive Biomarker (PRD): ACTA2 mRNA
Genes: ACTA2; ACTSA; ACTVS; GIG46
Study 29983350 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 29983350 — Predictive Biomarker (PRD): COL3A1 mRNA
Genes: COL3A1
Study 29983350 — Predictive Biomarker (PRD): CDH11 mRNA
Genes: CDH11
Study 24429400 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24429400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24429400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21812672 — Surrogate Endpoint (SUR): Hematologic response
Study 15310446 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 15310446 — Surrogate Endpoint (SUR): Blood pressure
Study 11181756 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 11181756 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11181756 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25394681 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 8988956 — Surrogate Endpoint (SUR): Blood pressure
Study 3655634 — Surrogate Endpoint (SUR): Blood pressure
Study 29891524 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29891524 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24301456 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 14661072 — Surrogate Endpoint (SUR): Bone mineral density
Study 8373604 — Surrogate Endpoint (SUR): Blood pressure
Study 31567817 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31567817 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17092253 — Predictive Biomarker (PRD): FCGR2A
Genes: CD32; CD32A; IGFR2; CDw32; Fc-gamma-RIIa; FcgammaRIIa
Study 17092253 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10162148 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6651284 — Surrogate Endpoint (SUR): Serum uric acid
Study 21603859 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16331341 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7941942 — Surrogate Endpoint (SUR): Blood pressure
Study 29209731 — Predictive Biomarker (PRD): TSTD1 mRNA
Genes: TSTD1; KAT
Study 25992279 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24617227 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24617227 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24617227 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16595025 — Predictive Biomarker (PRD): Hormone receptor
Study 11112112 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27267111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16295047 — Surrogate Endpoint (SUR): Blood pressure
Study 9457403 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3654947 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 28134748 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 25314004 — Surrogate Endpoint (SUR): Bone mineral density
Study 21124762 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21124762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21124762 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16776699 — Surrogate Endpoint (SUR): Blood pressure
Study 8095894 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28460534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30547732 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 15073266 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 8034208 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 2498089 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 4413081 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26410620 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 19301089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19301089 — Surrogate Endpoint (SUR): Bone mineral density
Study 17049060 — Surrogate Endpoint (SUR): Serum creatinine
Study 30187345 — Surrogate Endpoint (SUR): Blood pressure
Study 30187345 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19887860 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25256660 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 16108890 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9989541 — Surrogate Endpoint (SUR): Blood pressure
Study 30692241 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 30692241 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 30692241 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 30692241 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 30692241 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 30692241 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 22451021 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 20142306 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20051840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20051840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8401640 — Surrogate Endpoint (SUR): Bacterial count
Study 26456487 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18466801 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26829596 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 26829596 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 24267005 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15812409 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11956391 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30593607 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 26808856 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 21624734 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 19699335 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10069684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31628677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28104990 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28104990 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23521470 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study 19200384 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16766855 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16766855 — Surrogate Endpoint (SUR): Blood pressure
Study 11748103 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 26408513 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 21288364 — Surrogate Endpoint (SUR): Blood pressure
Study 9250108 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22522344 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 31688081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15193553 — Surrogate Endpoint (SUR): Bone mineral density
Study 8054075 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 14967268 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 9401425 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 8427657 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 8427657 — Surrogate Endpoint (SUR): Blood pressure
Study 26193978 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 18312764 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6430605 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 15692919 — Surrogate Endpoint (SUR): Serum creatinine