TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27592224 — Predictive Biomarker (PRD): SCARA3 mRNA
Genes: SCARA3; CSR
Study 9477052 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 2795592 — Surrogate Endpoint (SUR): Blood pressure
Study 346293 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 346293 — Surrogate Endpoint (SUR): Serum creatinine
Study 28806982 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 12536650 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23981966 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17716376 — Surrogate Endpoint (SUR): Blood pressure
Study 3303001 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 25600169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23281174 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 22452896 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17298881 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 17298881 — Surrogate Endpoint (SUR): Bone mineral density
Study 15379144 — Surrogate Endpoint (SUR): Blood pressure
Study 2930809 — Predictive Biomarker (PRD): PHLPP1 mRNA
Genes: PHLPP1; KIAA0606; PHLPP; PLEKHE1; SCOP
Study 328327 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 23415672 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study 23415672 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 23415672 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30577785 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17848625 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 2643864 — Surrogate Endpoint (SUR): Blood pressure
Study 2643864 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2643864 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21106710 — Surrogate Endpoint (SUR): Bone mineral density
Study 23147329 — Surrogate Endpoint (SUR): Blood pressure
Study 20545244 — Surrogate Endpoint (SUR): Blood pressure
Study 12412675 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27022941 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 11535842 — Surrogate Endpoint (SUR): Blood pressure
Study 29903845 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18656328 — Surrogate Endpoint (SUR): Blood pressure
Study 16301338 — Surrogate Endpoint (SUR): Blood pressure
Study 10811043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10811043 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25847473 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15367189 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16550750 — Surrogate Endpoint (SUR): Serum calcium
Study 1479003 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29671368 — Safety Biomarker (SAF): Reactive oxygen species
Study 20230403 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study 20230403 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15655124 — Surrogate Endpoint (SUR): Blood pressure
Study 7796586 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 1306851 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1306851 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 22327755 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18341756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18341756 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8953203 — Surrogate Endpoint (SUR): Blood pressure
Study 7138951 — Surrogate Endpoint (SUR): Blood pressure
Study 28304242 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28304242 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25651842 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 25651842 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 25651842 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 9745994 — Surrogate Endpoint (SUR): Blood pressure
Study 29177605 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16950285 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 11467759 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11467759 — Surrogate Endpoint (SUR): Blood pressure
Study 11467759 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9575675 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 22088858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16355341 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16355341 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 16355341 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 31912801 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 18953855 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 9273226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9273226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 1515386 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 22152974 — Surrogate Endpoint (SUR): Serum potassium
Study 15610835 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11594574 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9701719 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9701719 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27998910 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27717532 — Surrogate Endpoint (SUR): Blood pressure
Study 26413529 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28139023 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 23052568 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 19095857 — Surrogate Endpoint (SUR): Blood pressure
Study 15526246 — Surrogate Endpoint (SUR): Blood pressure
Study 30781485 — Surrogate Endpoint (SUR): Blood pressure
Study 30781485 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30781485 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1937998 — Surrogate Endpoint (SUR): Blood pressure
Study 23782555 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 17057609 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30416083 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 25048506 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 22901973 — Surrogate Endpoint (SUR): Blood pressure
Study 22901973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11573752 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 9758087 — Surrogate Endpoint (SUR): Blood pressure
Study 10649811 — Surrogate Endpoint (SUR): Bone mineral density
Study 10649811 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7073026 — Surrogate Endpoint (SUR): Blood pressure
Study 22460728 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 12055563 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 10663352 — Surrogate Endpoint (SUR): Bone mineral density
Study 22528813 — Surrogate Endpoint (SUR): Blood pressure
Study 28053275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23219108 — Surrogate Endpoint (SUR): Serum creatinine
Study 23219108 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21854503 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 21854503 — Surrogate Endpoint (SUR): Serum calcium
Study 9383226 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9383226 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3534869 — Surrogate Endpoint (SUR): Blood pressure
Study 8320744 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 18511016 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12767369 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19095726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19095726 — Surrogate Endpoint (SUR): Blood pressure
Study 10996348 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9024260 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3310297 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30064491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25952495 — Surrogate Endpoint (SUR): Blood pressure
Study 24030939 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19014494 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 17147795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14614165 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 14614165 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 14614165 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 11374857 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31591063 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31591063 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 29118087 — Surrogate Endpoint (SUR): Total kidney volume
Study 21451504 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 26063688 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26063688 — Surrogate Endpoint (SUR): Blood pressure
Study 19747937 — Surrogate Endpoint (SUR): Blood pressure
Study 11408369 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 11408369 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 11408369 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12847531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12847531 — Monitoring Biomarker (MOI): Procalcitonin
Study 29318656 — Predictive Biomarker (PRD): NPAS2 mRNA
Genes: NPAS2; BHLHE9; MOP4; PASD4
Study 24743880 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24743880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11978262 — Surrogate Endpoint (SUR): Blood pressure
Study 11978262 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28605609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3058919 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27923410 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study 27923410 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18334143 — Surrogate Endpoint (SUR): Serum creatinine
Study 16608935 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12911866 — Surrogate Endpoint (SUR): Blood pressure
Study 11313239 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9115157 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 21248446 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19064532 — Surrogate Endpoint (SUR): Blood pressure
Study 23047713 — Surrogate Endpoint (SUR): Blood pressure
Study 12742991 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12742991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9085015 — Surrogate Endpoint (SUR): Blood pressure
Study 29490024 — Predictive Biomarker (PRD): MAG mRNA
Genes: MAG; GMA
Study 9288223 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 3554804 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 27924635 — Surrogate Endpoint (SUR): Blood pressure
Study 2454893 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28680370 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 25869875 — Surrogate Endpoint (SUR): Blood pressure
Study 21212064 — Predictive Biomarker (PRD): Microsatellite instability
Study 18788531 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18788531 — Surrogate Endpoint (SUR): Blood pressure
Study 15893416 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 15893416 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 12610034 — Surrogate Endpoint (SUR): Blood pressure
Study 27287343 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27287343 — Safety Biomarker (SAF): BDNF
Study 15486066 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2511910 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2511910 — Surrogate Endpoint (SUR): Blood pressure
Study 24114402 — Surrogate Endpoint (SUR): Bone mineral density
Study 22315155 — Surrogate Endpoint (SUR): Serum testosterone
Study 21980205 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9778203 — Surrogate Endpoint (SUR): Blood pressure
Study 7937860 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 2455114 — Surrogate Endpoint (SUR): Blood pressure
Study 24777691 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11145109 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9352757 — Surrogate Endpoint (SUR): Blood pressure
Study 3596872 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26039521 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23222038 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 9279534 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27543277 — Surrogate Endpoint (SUR): Serum uric acid
Study 27543277 — Surrogate Endpoint (SUR): Blood pressure
Study 30118351 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 26313017 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 17786079 — Surrogate Endpoint (SUR): Serum creatinine
Study 17786079 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 15177521 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15177521 — Surrogate Endpoint (SUR): Blood pressure
Study 9498468 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 9498468 — Predictive Biomarker (PRD): CLSTN2 mRNA
Genes: CLSTN2; CS2
Study 9498468 — Predictive Biomarker (PRD): CLSTN1 mRNA
Genes: CLSTN1; CS1; KIAA0911
Study 30789807 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 29018027 — Surrogate Endpoint (SUR): Blood pressure
Study 17627016 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 15899724 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25524951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14757693 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 11783697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11783697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10102907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 594790 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 10451950 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2630295 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2630295 — Surrogate Endpoint (SUR): Blood pressure
Study 15607618 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 9291700 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 26674087 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12437859 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10851564 — Surrogate Endpoint (SUR): Blood pressure
Study 22019112 — Surrogate Endpoint (SUR): Blood pressure
Study 21439539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25814780 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 20886788 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20886788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20886788 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10981087 — Surrogate Endpoint (SUR): Blood pressure
Study 6366719 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6366719 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20038244 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17209957 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15616799 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 189334 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31288177 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 1782971 — Surrogate Endpoint (SUR): Serum calcium
Study 1782971 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31940543 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 25095811 — Surrogate Endpoint (SUR): Blood pressure
Study 28333551 — Surrogate Endpoint (SUR): Blood pressure
Study 25883031 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20032902 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11559318 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 3169108 — Surrogate Endpoint (SUR): Blood pressure
Study 25236582 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19005898 — Surrogate Endpoint (SUR): Blood pressure
Study 1616156 — Surrogate Endpoint (SUR): Blood pressure
Study 6237623 — Surrogate Endpoint (SUR): Blood pressure
Study 11546663 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11546663 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11546663 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 29992026 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29992026 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 29992026 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15897552 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18089984 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30572979 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1459316 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1459316 — Surrogate Endpoint (SUR): Blood pressure
Study 25701070 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20647958 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17211497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31164265 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31164265 — Predictive Biomarker (PRD): Hormone receptor
Study 15972357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12133434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10613616 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 25043339 — Surrogate Endpoint (SUR): Bone mineral density
Study 11924916 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29584518 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23549909 — Surrogate Endpoint (SUR): Blood pressure
Study 18349202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10981070 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1676621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29650949 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 27633841 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24714359 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20822474 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 12502668 — Surrogate Endpoint (SUR): Blood pressure
Study 8911510 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 20375277 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 11486702 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31465092 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 24954781 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19008007 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 19008007 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 19008007 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18219838 — Surrogate Endpoint (SUR): Serum potassium
Study 8329290 — Surrogate Endpoint (SUR): Blood pressure
Study 19022964 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16910917 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16910917 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9020242 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9020242 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24716671 — Surrogate Endpoint (SUR): Blood pressure
Study 23725917 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein