TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19896082 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28393633 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 18420099 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18420099 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18420099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17063993 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20416290 — Safety Biomarker (SAF): Reactive oxygen species
Study 29800466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9019639 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9019639 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9019639 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9019639 — Surrogate Endpoint (SUR): Blood pressure
Study 28264983 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 7863489 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11090727 — Surrogate Endpoint (SUR): Blood pressure
Study 9180665 — Surrogate Endpoint (SUR): Blood pressure
Study 31972657 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 29803816 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 18041735 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 8625493 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 8625493 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 3894277 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16729229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16729229 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7801618 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 21770897 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 21770897 — Safety Biomarker (SAF): Reactive oxygen species
Study 19716456 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 11059223 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 22995802 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22995802 — Surrogate Endpoint (SUR): Blood pressure
Study 19080096 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 3550098 — Surrogate Endpoint (SUR): Blood pressure
Study 21914062 — Monitoring Biomarker (MOI): HBV DNA
Study 19783710 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27704313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20457540 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 10560994 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 11102590 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8165591 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3080694 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 28628707 — Surrogate Endpoint (SUR): Blood pressure
Study 22466697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16815137 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16815137 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16815137 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29703978 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 23857798 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 17361524 — Predictive Biomarker (PRD): CBX1 mRNA
Genes: CBX1; CBX
Study 17361524 — Surrogate Endpoint (SUR): Serum testosterone
Study 1725447 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 1725447 — Surrogate Endpoint (SUR): Blood pressure
Study 6617205 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 30719589 — Surrogate Endpoint (SUR): Bone mineral density
Study 30719589 — Surrogate Endpoint (SUR): New morphometric vertebral fractures
Study 24703722 — Predictive Biomarker (PRD): CD6 mRNA
Genes: CD6
Study 19775046 — Surrogate Endpoint (SUR): Blood pressure
Study 11148432 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 9517944 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26253568 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26253568 — Surrogate Endpoint (SUR): Blood pressure
Study 21300709 — Surrogate Endpoint (SUR): Blood pressure
Study 11772239 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 11772239 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 11772239 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 26343780 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21701326 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 19225210 — Surrogate Endpoint (SUR): Blood pressure
Study 15650459 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15650459 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23725518 — Surrogate Endpoint (SUR): Serum creatinine
Study 18328360 — Surrogate Endpoint (SUR): Blood pressure
Study 31072395 — Surrogate Endpoint (SUR): Bone mineral density
Study 29949494 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26176644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31257405 — Surrogate Endpoint (SUR): Bone mineral density
Study 29134891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15943824 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15943824 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 8722350 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6362846 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31201197 — Predictive Biomarker (PRD): TICAM2 mRNA
Genes: TICAM2; TIRAP3; TIRP; TRAM
Study 20497522 — Surrogate Endpoint (SUR): Blood pressure
Study 2563314 — Surrogate Endpoint (SUR): Blood pressure
Study 10678500 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30689703 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29031002 — Surrogate Endpoint (SUR): Blood pressure
Study 29031002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29031002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27920508 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2233283 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 20180330 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 18220025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18220025 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18220025 — Surrogate Endpoint (SUR): Blood pressure
Study 21413846 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 11158283 — Surrogate Endpoint (SUR): Blood pressure
Study 8421475 — Surrogate Endpoint (SUR): Bone mineral density
Study 8421475 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31702047 — Surrogate Endpoint (SUR): Blood pressure
Study 22176029 — Predictive Biomarker (PRD): DSPP mRNA
Genes: DSPP
Study 22176029 — Predictive Biomarker (PRD): DMP1 mRNA
Genes: DMP1
Study 22176029 — Predictive Biomarker (PRD): GAPDH mRNA
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 12594304 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11783226 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27876583 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 21897859 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 8310507 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24457911 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23307525 — Surrogate Endpoint (SUR): Blood pressure
Study 19032914 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16204287 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 8099978 — Surrogate Endpoint (SUR): Blood pressure
Study 29767793 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29767793 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 29767793 — Safety Biomarker (SAF): Reactive oxygen species
Study 29767793 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29767793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18671864 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 15941372 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 25940724 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25940724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24015698 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17094387 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29078256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27580595 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 15672210 — Surrogate Endpoint (SUR): Bone mineral density
Study 10048795 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 10048795 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 10048795 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 10048795 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 6360689 — Surrogate Endpoint (SUR): Blood pressure
Study 29140444 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 24768130 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 19709893 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8946434 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 8946434 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 2014928 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30935317 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 1778878 — Surrogate Endpoint (SUR): Serum creatinine
Study 29945396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 12627352 — Monitoring Biomarker (MOI): HBV DNA
Study 10487307 — Surrogate Endpoint (SUR): Blood pressure
Study 1321194 — Surrogate Endpoint (SUR): Blood pressure
Study 29693035 — Surrogate Endpoint (SUR): Blood pressure
Study 15711607 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15711607 — Surrogate Endpoint (SUR): Serum creatinine
Study 19143666 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 15200755 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23321403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23321403 — Surrogate Endpoint (SUR): Blood pressure
Study 12173800 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7614501 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 7614501 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29267553 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 24052035 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10401023 — Surrogate Endpoint (SUR): Serum potassium
Study 1909692 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 26890969 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16109577 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 10825039 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2191876 — Surrogate Endpoint (SUR): Blood pressure
Study 511803 — Surrogate Endpoint (SUR): Blood pressure
Study 25438232 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23613255 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21713728 — Surrogate Endpoint (SUR): Blood pressure
Study 16385331 — Surrogate Endpoint (SUR): Blood pressure
Study 12709466 — Surrogate Endpoint (SUR): Blood pressure
Study 8610867 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8610867 — Surrogate Endpoint (SUR): Blood pressure
Study 31451009 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31451009 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31451009 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22682298 — Surrogate Endpoint (SUR): Blood pressure
Study 29350603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22241259 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 18279056 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12520528 — Surrogate Endpoint (SUR): Bone mineral density
Study 8968175 — Surrogate Endpoint (SUR): Blood pressure
Study 12773075 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12773075 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27417982 — Surrogate Endpoint (SUR): Blood pressure
Study 12585781 — Surrogate Endpoint (SUR): Bone mineral density
Study 30465630 — Surrogate Endpoint (SUR): Blood pressure
Study 19698013 — Surrogate Endpoint (SUR): Blood pressure
Study 1553580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29967045 — Surrogate Endpoint (SUR): Blood pressure
Study 22205149 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10235511 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28966304 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 14693611 — Surrogate Endpoint (SUR): Blood pressure
Study 9526939 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9526939 — Surrogate Endpoint (SUR): Blood pressure
Study 31397128 — Safety Biomarker (SAF): Hyaluronic acid
Study 10426879 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7056271 — Surrogate Endpoint (SUR): Blood pressure
Study 28533100 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27914656 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18332454 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 16105530 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 11834648 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26345405 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25761430 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 10929769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10929769 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10929769 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25964246 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25964246 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25964246 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9659302 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31219254 — Surrogate Endpoint (SUR): Blood pressure
Study 23585901 — Safety Biomarker (SAF): BDNF
Study 25332476 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 20411443 — Surrogate Endpoint (SUR): Blood pressure
Study 17506591 — Surrogate Endpoint (SUR): Blood pressure
Study 12419084 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31133052 — Surrogate Endpoint (SUR): Serum creatinine
Study 22057473 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 11960266 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11960266 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 2698902 — Surrogate Endpoint (SUR): Blood pressure
Study 20830241 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16639473 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16639473 — Predictive Biomarker (PRD): HADH mRNA
Genes: HADH; HAD; HAD1; HADHSC; SCHAD
Study 28548024 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9289451 — Surrogate Endpoint (SUR): Blood pressure
Study 30127595 — Surrogate Endpoint (SUR): Blood pressure
Study 17803435 — Surrogate Endpoint (SUR): Blood pressure
Study 28664036 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 28664036 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 15361758 — Surrogate Endpoint (SUR): Blood pressure
Study 2906345 — Surrogate Endpoint (SUR): Blood pressure
Study 25137843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7392895 — Surrogate Endpoint (SUR): Blood pressure
Study 17473654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31042581 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study 31042581 — Monitoring Biomarker (MOI): HBV DNA
Study 29494476 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24858952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18328014 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10100079 — Surrogate Endpoint (SUR): Blood pressure
Study 6095635 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25251800 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22265215 — Predictive Biomarker (PRD): DRAM1 mRNA
Genes: DRAM1; DRAM
Study 18377783 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18377783 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15814545 — Surrogate Endpoint (SUR): Blood pressure
Study 12168963 — Surrogate Endpoint (SUR): Blood pressure
Study 30641707 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23252768 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 21069358 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 19028707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19028707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10551636 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 8565028 — Surrogate Endpoint (SUR): Blood pressure
Study 8565028 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29309486 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29309486 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17344493 — Predictive Biomarker (PRD): RGL1 mRNA
Genes: RGL1; KIAA0959; RGL
Study 26826565 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 24628042 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10029962 — Surrogate Endpoint (SUR): Blood pressure
Study 7574780 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 23081753 — Predictive Biomarker (PRD): BOC mRNA
Genes: BOC; UNQ604/PRO1190
Study 23081753 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 15253884 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15253884 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8220974 — Surrogate Endpoint (SUR): Bone mineral density
Study 19378437 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19378437 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8868311 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 23418668 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 17697551 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17697551 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9730356 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 29208626 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 29208626 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25876344 — Surrogate Endpoint (SUR): Serum testosterone
Study 18332449 — Surrogate Endpoint (SUR): Blood pressure
Study 12914790 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 12914790 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12914790 — Predictive Biomarker (PRD): CES2 mRNA
Genes: CES2; ICE
Study 8588384 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 17680205 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16080808 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16080808 — Surrogate Endpoint (SUR): Blood pressure
Study 11136842 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2542549 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2542549 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16945045 — Surrogate Endpoint (SUR): Blood pressure
Study 9246958 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 17671280 — Predictive Biomarker (PRD): GRIK4 mRNA
Genes: GRIK4; GRIK
Study 17671280 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 24636340 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 24636340 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD