TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26268133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26268133 — Safety Biomarker (SAF): Interleukin 1
Study 20146874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16980833 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 15151689 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8218538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2454374 — Surrogate Endpoint (SUR): Blood pressure
Study 25738668 — Predictive Biomarker (PRD): Hormone receptor
Study 23385648 — Surrogate Endpoint (SUR): Blood pressure
Study 12602466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12602466 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12602466 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 31779987 — Surrogate Endpoint (SUR): Blood pressure
Study 23901839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23901839 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 31973596 — Predictive Biomarker (PRD): DKK3 mRNA
Genes: DKK3; REIC; UNQ258/PRO295
Study 7798164 — Surrogate Endpoint (SUR): Blood pressure
Study 23303045 — Predictive Biomarker (PRD): TRIM32 mRNA
Genes: TRIM32; HT2A
Study 16518962 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19561263 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14754702 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15330492 — Surrogate Endpoint (SUR): Blood pressure
Study 8131343 — Surrogate Endpoint (SUR): Serum calcium
Study 8131343 — Surrogate Endpoint (SUR): Serum creatinine
Study 642493 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28382336 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25880486 — Surrogate Endpoint (SUR): Blood pressure
Study 11444676 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8359082 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 31977076 — Surrogate Endpoint (SUR): Blood pressure
Study 24595942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24595942 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24595942 — Safety Biomarker (SAF): Interleukin 12
Study 22265697 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19576321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19576321 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7905722 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31905090 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 25667241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24928269 — Safety Biomarker (SAF): Hyaluronic acid
Study 17433007 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 16372579 — Surrogate Endpoint (SUR): Blood pressure
Study 9815522 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9815522 — Predictive Biomarker (PRD): Hormone receptor
Study 21681372 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2968761 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2968761 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30839075 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19591898 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 14698362 — Surrogate Endpoint (SUR): Blood pressure
Study 10652960 — Surrogate Endpoint (SUR): Bone mineral density
Study 24316704 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 28552588 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28552588 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 10338458 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2045181 — Surrogate Endpoint (SUR): Blood pressure
Study 6994786 — Surrogate Endpoint (SUR): Blood pressure
Study 21270331 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 8520640 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 2146047 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 26002204 — Predictive Biomarker (PRD): TSTD1 mRNA
Genes: TSTD1; KAT
Study 11566255 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 17472992 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 17472992 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 17472992 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 17472992 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 9615797 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9615797 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19660420 — Surrogate Endpoint (SUR): Serum creatinine
Study 11386413 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8002509 — Surrogate Endpoint (SUR): Plasma ammonia
Study 15339330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8032580 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 8032580 — Surrogate Endpoint (SUR): Blood pressure
Study 23087776 — Surrogate Endpoint (SUR): Blood pressure
Study 16356805 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10402814 — Surrogate Endpoint (SUR): Blood pressure
Study 7538179 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21775973 — Surrogate Endpoint (SUR): Blood pressure
Study 21784838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21784838 — Surrogate Endpoint (SUR): Serum uric acid
Study 16766419 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 19481278 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10894268 — Predictive Biomarker (PRD): GART mRNA
Genes: GART; PGFT; PRGS
Study 10894268 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1638713 — Safety Biomarker (SAF): 51Cr-EDTA
Study 1638713 — Surrogate Endpoint (SUR): Blood pressure
Study 20659611 — Surrogate Endpoint (SUR): Blood pressure
Study 14996592 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10094742 — Predictive Biomarker (PRD): NELFCD mRNA
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 80525 — Surrogate Endpoint (SUR): Serum uric acid
Study 24159176 — Predictive Biomarker (PRD): TNFAIP3 mRNA
Genes: TNFAIP3; OTUD7C
Study 11158407 — Surrogate Endpoint (SUR): Blood pressure
Study 8117177 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8117177 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28219107 — Surrogate Endpoint (SUR): Blood pressure
Study 19013603 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 19013603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19013603 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8013688 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 31654838 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 16113424 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9623560 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 9623560 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9623560 — Surrogate Endpoint (SUR): Serum calcium
Study 21186536 — Monitoring Biomarker (MOI): HBV DNA
Study 29246139 — Surrogate Endpoint (SUR): Blood pressure
Study 8739611 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 29483060 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27383499 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17578722 — Surrogate Endpoint (SUR): Blood pressure
Study 30887050 — Surrogate Endpoint (SUR): Serum creatinine
Study 8011799 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23639779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15209578 — Surrogate Endpoint (SUR): Serum creatinine
Study 11755455 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 11755455 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11755455 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31924662 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 28463849 — Surrogate Endpoint (SUR): Serum uric acid
Study 28463849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23353589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23353589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23353589 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18280129 — Surrogate Endpoint (SUR): Blood pressure
Study 22815078 — Predictive Biomarker (PRD): STAM mRNA
Genes: STAM; STAM1
Study 8647514 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28513179 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31941864 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24103587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24103587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17074112 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 17074112 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 17074112 — Surrogate Endpoint (SUR): Bone mineral density
Study 9024732 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9024732 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14619336 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 27864247 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1532321 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18347203 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23831177 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 20024643 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 2148508 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 2148508 — Surrogate Endpoint (SUR): Blood pressure
Study 28530238 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 28530238 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): miR-146a-5p
Genes: MIR146A
Study 28530238 — Monitoring Biomarker (MOI): miR-146b-5p
Genes: MIR146B
Study 28530238 — Safety Biomarker (SAF): miR-146b
Genes: MIR146B
Study 28530238 — Monitoring Biomarker (MOI): miR-425-3p
Genes: MIR425
Study 28530238 — Monitoring Biomarker (MOI): miR-24-3p
Study 19910826 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19910826 — Surrogate Endpoint (SUR): Blood pressure
Study 29879676 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 24428972 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 24428972 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24428972 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 24428972 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 24428972 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 7475198 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21331065 — Surrogate Endpoint (SUR): Blood pressure
Study 12878742 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31805787 — Surrogate Endpoint (SUR): Blood pressure
Study 12352910 — Surrogate Endpoint (SUR): Serum creatinine
Study 3605563 — Surrogate Endpoint (SUR): Blood pressure
Study 24465438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20664561 — Surrogate Endpoint (SUR): Serum creatinine
Study 11558625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8465839 — Surrogate Endpoint (SUR): Blood pressure
Study 8465839 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27552643 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23045301 — Surrogate Endpoint (SUR): Serum creatinine
Study 7541051 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 26296857 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17196876 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 16261464 — Surrogate Endpoint (SUR): Blood pressure
Study 19101237 — Surrogate Endpoint (SUR): Serum creatinine
Study 19101237 — Surrogate Endpoint (SUR): Blood pressure
Study 21180677 — Safety Biomarker (SAF): Hyaluronic acid
Study 16322118 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16322118 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10098569 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 10098569 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15674301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16751018 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 16751018 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16751018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7643542 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7643542 — Surrogate Endpoint (SUR): Blood pressure
Study 30812036 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 22874485 — Surrogate Endpoint (SUR): Blood pressure
Study 22874485 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2118879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2118879 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31759966 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 21270914 — Surrogate Endpoint (SUR): Serum calcium
Study 19858350 — Surrogate Endpoint (SUR): Blood pressure
Study 11134430 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11134430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11134430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2887951 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 29392419 — Predictive Biomarker (PRD): ARL6IP1 mRNA
Genes: ARL6IP1; ARL6IP; ARMER; KIAA0069
Study 12525515 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 12525515 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 12525515 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 27390979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27390979 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 27390979 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24974847 — Predictive Biomarker (PRD): TANC1 mRNA
Genes: TANC1; KIAA1728
Study 19579590 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2972756 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12911781 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 10575594 — Surrogate Endpoint (SUR): Bone mineral density
Study 27775992 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 25454363 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 19524752 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 14616423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 6362342 — Surrogate Endpoint (SUR): Blood pressure
Study 28964569 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24237035 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study 21968605 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 2065463 — Surrogate Endpoint (SUR): Blood pressure
Study 2093746 — Surrogate Endpoint (SUR): Blood pressure
Study 29663407 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 29663407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27769609 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22223479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10965615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10965615 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 10965615 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8418166 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21349204 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 19055289 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19055289 — Surrogate Endpoint (SUR): Blood pressure
Study 16541377 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9189304 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8467025 — Surrogate Endpoint (SUR): Blood pressure
Study 17418728 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 15466458 — Surrogate Endpoint (SUR): Blood pressure
Study 10682436 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7615947 — Surrogate Endpoint (SUR): Blood pressure
Study 2515215 — Surrogate Endpoint (SUR): Blood pressure
Study 326447 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 27521672 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19581013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 2659953 — Surrogate Endpoint (SUR): Bone mineral density
Study 31050562 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22938659 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16087989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16087989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16087989 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15038626 — Surrogate Endpoint (SUR): Blood pressure
Study 26333543 — Surrogate Endpoint (SUR): Blood pressure
Study 3191933 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18665413 — Surrogate Endpoint (SUR): Blood pressure
Study 11111140 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 26159014 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22149319 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 22149319 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 7774326 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 14607452 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 30736479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18264836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18264836 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18264836 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7994260 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23564922 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23564922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21864370 — Predictive Biomarker (PRD): LAP3 mRNA
Genes: LAP3; LAPEP; PEPS
Study 12855084 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 31021112 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 24468997 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1285937 — Surrogate Endpoint (SUR): Blood pressure
Study 29668535 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 29668535 — Surrogate Endpoint (SUR): Bone mineral density
Study 27567760 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 25320235 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25320235 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 25320235 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22782510 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10496190 — Surrogate Endpoint (SUR): Blood pressure