TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24890858 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 24890858 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 24891132 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 24891132 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 24891132 — Predictive Biomarker (PRD): GABRE mRNA
Genes: GABRE
Study 24895163 — Surrogate Endpoint (SUR): Blood pressure
Study 24898091 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24898091 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24898549 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24898549 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 24898826 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 24898826 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 24898826 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 24898826 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 24898826 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 24898826 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 24899155 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24903080 — Predictive Biomarker (PRD): Hormone receptor
Study 24903080 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 24903189 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24903629 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 24903795 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 24903982 — Surrogate Endpoint (SUR): Blood pressure
Study 24905490 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24905795 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 24907357 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24907357 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 24907635 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 24907636 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24907636 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24912489 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 24912489 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 24912489 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 24912489 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 24912489 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCNE1 mRNA
Genes: CCNE1; CCNE
Study 24912489 — Predictive Biomarker (PRD): IRS2 mRNA
Genes: IRS2
Study 24912489 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study 24912489 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 24912564 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24912797 — Safety Biomarker (SAF): Interleukin 1
Study 24913066 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24914120 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24916506 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 24916506 — Predictive Biomarker (PRD): PTK2
Genes: FAK; FADK; FAK1; PPP1R71
Study 24916507 — Predictive Biomarker (PRD): KLF1 mRNA
Genes: KLF1; EKLF
Study 24916507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 24916507 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24916771 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24918167 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 24918982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24919462 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 24919854 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 24919854 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study 24919854 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 24923295 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 24923295 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 24923295 — Predictive Biomarker (PRD): BCOR mRNA
Genes: BCOR; KIAA1575
Study 24923295 — Predictive Biomarker (PRD): CEBPZ mRNA
Genes: CEBPZ; CBF2
Study 24923295 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 24923295 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 24923295 — Predictive Biomarker (PRD): SPRY2 mRNA
Genes: SPRY2
Study 24923356 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 24923356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24923792 — Surrogate Endpoint (SUR): Bone mineral density
Study 24924750 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 24926953 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24926953 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24927856 — Predictive Biomarker (PRD): CD37 mRNA
Genes: CD37; TSPAN26
Study 24928772 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24929258 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 24929893 — Predictive Biomarker (PRD): AZGP1 mRNA
Genes: AZGP1; ZAG; ZNGP1
Study 24934364 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24934506 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 24935348 — Surrogate Endpoint (SUR): Blood pressure
Study 24939214 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24939214 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24939214 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24944546 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 24948692 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 24950186 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 24950779 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24951039 — Surrogate Endpoint (SUR): Blood pressure
Study 24951039 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24951123 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24952730 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 24952730 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 24952730 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 24952730 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 24953487 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24954193 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 24956535 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 24962156 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24963042 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 24963497 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 24964084 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24965748 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24965999 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 24965999 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24967244 — Surrogate Endpoint (SUR): Serum creatinine
Study 24970686 — Predictive Biomarker (PRD): SLC12A1 mRNA
Genes: SLC12A1; NKCC2
Study 24970686 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24970782 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24970932 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 24974232 — Surrogate Endpoint (SUR): Serum creatinine
Study 24974232 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24975273 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 24975273 — Predictive Biomarker (PRD): DUSP10 mRNA
Genes: DUSP10; MKP5
Study 24975273 — Predictive Biomarker (PRD): TRAK1 mRNA
Genes: TRAK1; KIAA1042; OIP106
Study 24975273 — Predictive Biomarker (PRD): NRIP1 mRNA
Genes: NRIP1
Study 24975273 — Predictive Biomarker (PRD): THBD mRNA
Genes: THBD; THRM
Study 24978858 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24979578 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 24981579 — Surrogate Endpoint (SUR): Blood pressure
Study 24982357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24982357 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24982357 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24982357 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24982357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24982357 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24983357 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 24986638 — Predictive Biomarker (PRD): AKAP12 mRNA
Genes: AKAP12; AKAP250
Study 24986638 — Predictive Biomarker (PRD): CAMK2D mRNA
Genes: CAMK2D; CAMKD
Study 24986689 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 24986689 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 24986689 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 24986689 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 24987412 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 24988449 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24988476 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 24988476 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 24988476 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24990396 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 24991041 — Safety Biomarker (SAF): MTHFR
Study 24991089 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24991089 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24991089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24992469 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 24992469 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24993530 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24996668 — Surrogate Endpoint (SUR): Serum creatinine
Study 24997153 — Predictive Biomarker (PRD): Liver iron
Study 24997153 — Surrogate Endpoint (SUR): Serum creatinine
Study 24997880 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 24999380 — Predictive Biomarker (PRD): GABRB3 mRNA
Genes: GABRB3
Study 25001321 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25001321 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25002028 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25002028 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25002028 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 25002194 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 25002964 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 25002964 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 25002964 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25005255 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25005255 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 25005255 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25005255 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 25005255 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25005255 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 25005444 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25006744 — Predictive Biomarker (PRD): MYO1D mRNA
Genes: MYO1D; KIAA0727
Study 25006744 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 25006744 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 25006744 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 25006744 — Predictive Biomarker (PRD): TGFB2 mRNA
Genes: TGFB2
Study 25006744 — Predictive Biomarker (PRD): MMP12 mRNA
Genes: MMP12; HME
Study 25007130 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25007130 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25007130 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 25007944 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25008917 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25008917 — Predictive Biomarker (PRD): APOBEC3G mRNA
Genes: APOBEC3G; MDS019
Study 25008917 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 25008917 — Safety Biomarker (SAF): Heat shock 70 kDa
Study 25009010 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 25009010 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 25009010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 25009010 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 25009010 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 25009010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 25009010 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 25010745 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 25012943 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 25012994 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 25013718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25013718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25013718 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 25013998 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25015177 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25015938 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25015938 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 25016003 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 25016003 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 25016003 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 25016482 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25016482 — Surrogate Endpoint (SUR): Sperm parameters
Study 25016924 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25016924 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25018910 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 25020262 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25022285 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25022596 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25022828 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 25022935 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 25022935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25023004 — Surrogate Endpoint (SUR): Blood pressure
Study 25023626 — Predictive Biomarker (PRD): KRT19 mRNA
Genes: KRT19
Study 25023626 — Predictive Biomarker (PRD): TWIST1 mRNA
Genes: TWIST1; BHLHA38; TWIST
Study 25023926 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25025963 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25027873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25027873 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25028353 — Surrogate Endpoint (SUR): Serum calcium
Study 25028485 — Predictive Biomarker (PRD): MCM8 mRNA
Genes: MCM8; C20orf154
Study 25028485 — Predictive Biomarker (PRD): SLC23A2 mRNA
Genes: SLC23A2; KIAA0238; NBTL1; SLC23A1; SVCT2; YSPL2
Study 25028485 — Predictive Biomarker (PRD): STK35 mRNA
Genes: STK35; CLIK1; PDIK1; STK35L1
Study 25028485 — Surrogate Endpoint (SUR): Blood pressure
Study 25029335 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study 25029335 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 25029335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25029335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25029335 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 25029335 — Safety Biomarker (SAF): Interleukin 1
Study 25030840 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 25030840 — Predictive Biomarker (PRD): LRAT mRNA
Genes: LRAT
Study 25030840 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25037863 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25038354 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25038774 — Surrogate Endpoint (SUR): Blood pressure
Study 25039025 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25042202 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 25042419 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25043069 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 25043320 — Predictive Biomarker (PRD): DISC1 mRNA
Genes: DISC1; KIAA0457
Study 25043597 — Predictive Biomarker (PRD): DHDDS mRNA
Genes: DHDDS; HDS
Study 25043869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25043869 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 25045579 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 25047061 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25047061 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 25047123 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25047123 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 25047123 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25047123 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 25047747 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25056500 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25056500 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 25056691 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 25056691 — Predictive Biomarker (PRD): RRAGB mRNA
Genes: RRAGB
Study 25057276 — Surrogate Endpoint (SUR): Blood pressure
Study 25060819 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25061140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25062507 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 25062744 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25063332 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 25064094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25070153 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25072443 — Surrogate Endpoint (SUR): Blood pressure
Study 25072816 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25073894 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25074036 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 25074070 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25074070 — Surrogate Endpoint (SUR): Blood pressure
Study 25074459 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25075128 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25077901 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25078269 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 25078269 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 25078269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 25078269 — Predictive Biomarker (PRD): MICB mRNA
Genes: MICB; PERB11.2
Study 25079400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25080540 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP