TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16508257 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 16508257 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12722967 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 3536644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24634333 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24634333 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 12360101 — Predictive Biomarker (PRD): NOD2 mRNA
Genes: NOD2; CARD15; IBD1
Study 29028556 — Surrogate Endpoint (SUR): Blood pressure
Study 24981955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17476007 — Surrogate Endpoint (SUR): Bone mineral density
Study 10684069 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 10684069 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 22345157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22345157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22345157 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20813685 — Surrogate Endpoint (SUR): Blood pressure
Study 6411479 — Surrogate Endpoint (SUR): Blood pressure
Study 23173831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23173831 — Surrogate Endpoint (SUR): Blood pressure
Study 7926977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7926977 — Safety Biomarker (SAF): Interleukin 1
Study 1105630 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 27109623 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 11707834 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 25315942 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22755276 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20798393 — Predictive Biomarker (PRD): ODC1 mRNA
Genes: ODC1
Study 7587688 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31135570 — Safety Biomarker (SAF): Hyaluronic acid
Study 25543972 — Surrogate Endpoint (SUR): Serum sodium
Study 17105880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17105880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29753420 — Surrogate Endpoint (SUR): Blood pressure
Study 17121049 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23600368 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23600368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12666705 — Safety Biomarker (SAF): Interleukin 1
Study 6789483 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11281560 — Surrogate Endpoint (SUR): Bone mineral density
Study 9337001 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 23474245 — Surrogate Endpoint (SUR): Blood pressure
Study 18728576 — Surrogate Endpoint (SUR): Blood pressure
Study 20489689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20489689 — Surrogate Endpoint (SUR): Blood pressure
Study 20489689 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2833920 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2833920 — Surrogate Endpoint (SUR): Blood pressure
Study 26902851 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 26902851 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 24288511 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 24288511 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8820475 — Surrogate Endpoint (SUR): Blood pressure
Study 8820475 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25827654 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16750703 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30222631 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 27633076 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 17274493 — Surrogate Endpoint (SUR): Bone mineral density
Study 12812815 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9029412 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 28994676 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14767239 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 14767239 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3121268 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10754364 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 20130232 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 20130232 — Predictive Biomarker (PRD): CCRL2 mRNA
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 20130232 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19095138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16213291 — Surrogate Endpoint (SUR): Serum creatinine
Study 30690293 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 24985959 — Surrogate Endpoint (SUR): Blood pressure
Study 16083526 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12394229 — Surrogate Endpoint (SUR): Serum sodium
Study 26284906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21969008 — Predictive Biomarker (PRD): GCH1 mRNA
Genes: GCH1; DYT5; GCH
Study 21969008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21969008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21969008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16611656 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14571611 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 29070768 — Surrogate Endpoint (SUR): Blood pressure
Study 20977582 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20977582 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20977582 — Surrogate Endpoint (SUR): Blood pressure
Study 16896999 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16896999 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10939785 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10939785 — Surrogate Endpoint (SUR): Blood pressure
Study 1476285 — Surrogate Endpoint (SUR): Blood pressure
Study 6727656 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 12021622 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 31262657 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31262657 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29635252 — Predictive Biomarker (PRD): PEAR1 mRNA
Genes: PEAR1; MEGF12
Study 29635252 — Predictive Biomarker (PRD): UGT2A1 mRNA
Genes: UGT2A1
Study 24144654 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24144654 — Surrogate Endpoint (SUR): Blood pressure
Study 20231521 — Surrogate Endpoint (SUR): Blood pressure
Study 27816804 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27816804 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23690341 — Surrogate Endpoint (SUR): Blood pressure
Study 7514238 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21933833 — Surrogate Endpoint (SUR): Blood pressure
Study 20698232 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 7293945 — Surrogate Endpoint (SUR): Serum calcium
Study 12658071 — Surrogate Endpoint (SUR): Blood pressure
Study 30100295 — Surrogate Endpoint (SUR): Blood pressure
Study 24809305 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24809305 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 24809305 — Surrogate Endpoint (SUR): Blood pressure
Study 14763665 — Surrogate Endpoint (SUR): Blood pressure
Study 17214336 — Predictive Biomarker (PRD): TK1 mRNA
Genes: TK1
Study 14623542 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8836901 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 1478292 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26580489 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26580489 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10429902 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 20824706 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 810765 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26354385 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26051926 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23333143 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23333143 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 23333143 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 21529841 — Predictive Biomarker (PRD): NFKB1 mRNA
Genes: NFKB1
Study 21529841 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 21529841 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 21529841 — Predictive Biomarker (PRD): TLR5 mRNA
Genes: TLR5; TIL3
Study 21529841 — Predictive Biomarker (PRD): IRAK1 mRNA
Genes: IRAK1; IRAK
Study 21529841 — Predictive Biomarker (PRD): NFKBIA mRNA
Genes: NFKBIA; IKBA; MAD3; NFKBI
Study 15492459 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 11769967 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 30130574 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 27619015 — Surrogate Endpoint (SUR): Blood pressure
Study 23922010 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 23922010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 3753363 — Surrogate Endpoint (SUR): Blood pressure
Study 27737722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15879332 — Surrogate Endpoint (SUR): Blood pressure
Study 12649124 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 26956031 — Surrogate Endpoint (SUR): Blood pressure
Study 14593351 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14593351 — Surrogate Endpoint (SUR): Blood pressure
Study 8999617 — Surrogate Endpoint (SUR): Blood pressure
Study 6373679 — Surrogate Endpoint (SUR): Blood pressure
Study 25335251 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 1574950 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31676258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31676258 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28870887 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26401946 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19278300 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29037093 — Surrogate Endpoint (SUR): Bone mineral density
Study 24711481 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24161482 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 11279797 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27413741 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27413741 — Surrogate Endpoint (SUR): Blood pressure
Study 11146577 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8077885 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30543266 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 25175425 — Predictive Biomarker (PRD): SPINK1 mRNA
Genes: SPINK1; PSTI
Study 25175425 — Predictive Biomarker (PRD): ETV1 mRNA
Genes: ETV1; ER81
Study 25175425 — Predictive Biomarker (PRD): ETV4 mRNA
Genes: ETV4; E1AF; PEA3
Study 25175425 — Predictive Biomarker (PRD): ETV5 mRNA
Genes: ETV5; ERM
Study 21707928 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 18839134 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 18839134 — Predictive Biomarker (PRD): INSIG2 mRNA
Genes: INSIG2
Study 30031660 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8677636 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8677636 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 20801233 — Surrogate Endpoint (SUR): Blood pressure
Study 29214863 — Surrogate Endpoint (SUR): Blood pressure
Study 20438378 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28826313 — Predictive Biomarker (PRD): FSTL1 mRNA
Genes: FSTL1; FRP
Study 28826313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28826313 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7525661 — Surrogate Endpoint (SUR): Serum creatinine
Study 27187435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27187435 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25887113 — Surrogate Endpoint (SUR): Blood pressure
Study 20609003 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16204359 — Surrogate Endpoint (SUR): Serum creatinine
Study 12704366 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 21521375 — Safety Biomarker (SAF): Interleukin 12
Study 19043984 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26185017 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20854382 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 20854382 — Safety Biomarker (SAF): Hepatitis A virus cellular receptor 1
Genes: HAVCR1; KIM1; TIM1; TIMD1
Study 16982943 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15339556 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 10726719 — Surrogate Endpoint (SUR): Blood pressure
Study 31237183 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 26960912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17683996 — Surrogate Endpoint (SUR): Bone mineral density
Study 18608549 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 18608549 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18608549 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16395099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8434246 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8434246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24903468 — Surrogate Endpoint (SUR): Blood pressure
Study 1350237 — Safety Biomarker (SAF): DRD2
Study 22460854 — Predictive Biomarker (PRD): PLAT mRNA
Genes: PLAT
Study 11791028 — Surrogate Endpoint (SUR): Blood pressure
Study 6763834 — Surrogate Endpoint (SUR): Blood pressure
Study 26880694 — Surrogate Endpoint (SUR): Blood pressure
Study 12370214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12370214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12370214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25879228 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25879228 — Surrogate Endpoint (SUR): Blood pressure
Study 17124431 — Surrogate Endpoint (SUR): Blood pressure
Study 17124431 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11578682 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11578682 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11578682 — Surrogate Endpoint (SUR): Blood pressure
Study 28155060 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 24617232 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24617232 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12684359 — Surrogate Endpoint (SUR): Blood pressure
Study 7772472 — Safety Biomarker (SAF): Hyaluronic acid
Study 31849000 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 28526625 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23345050 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 8154033 — Surrogate Endpoint (SUR): Serum creatinine
Study 15459595 — Surrogate Endpoint (SUR): Serum creatinine
Study 15459595 — Surrogate Endpoint (SUR): Blood pressure
Study 11174041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9253332 — Surrogate Endpoint (SUR): Blood pressure
Study 3320788 — Surrogate Endpoint (SUR): Blood pressure
Study 27714541 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27714541 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 20684675 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18201301 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8702086 — Surrogate Endpoint (SUR): Bone mineral density
Study 8702086 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 8702086 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 8702086 — Surrogate Endpoint (SUR): Serum calcium
Study 20014909 — Surrogate Endpoint (SUR): Blood pressure
Study 17585060 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 14739125 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 14739125 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14739125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21193552 — Surrogate Endpoint (SUR): Blood pressure
Study 30346099 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25451704 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19673941 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 19673941 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17909199 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17909199 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23940216 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23940216 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8605789 — Surrogate Endpoint (SUR): Blood pressure
Study 1874931 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23791497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21545190 — Safety Biomarker (SAF): Hyaluronic acid
Study 16485865 — Surrogate Endpoint (SUR): Blood pressure
Study 10470696 — Surrogate Endpoint (SUR): Pathological complete response
Study 424377 — Surrogate Endpoint (SUR): Blood pressure
Study 19858394 — Surrogate Endpoint (SUR): Serum creatinine
Study 15918060 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12483234 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 20525323 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 15886860 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15886860 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 7587256 — Surrogate Endpoint (SUR): Blood pressure
Study 30358116 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 17994478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 23688821 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19262219 — Surrogate Endpoint (SUR): Blood pressure
Study 1544220 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1544220 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 1544220 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 1544220 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 3907893 — Surrogate Endpoint (SUR): Blood pressure
Study 30468238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24795475 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 22613104 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20830787 — Monitoring Biomarker (MOI): HBV DNA
Study 18855259 — Surrogate Endpoint (SUR): Blood pressure
Study 29045941 — Surrogate Endpoint (SUR): Blood pressure
Study 17926619 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17926619 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 17926619 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11512648 — Surrogate Endpoint (SUR): Blood pressure
Study 26436865 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26436865 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21852334 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17267590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17267590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2