TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01286389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01286389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01286389 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT03465917 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01239979 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT01239979 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT01679587 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01679587 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01679587 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study NCT01679587 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study NCT00474851 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01553279 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT04556552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05439460 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05439460 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00707655 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03255512 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01693627 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03734211 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03734211 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03858166 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02652793 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03203135 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00003026 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT02559882 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01370135 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01370135 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00752960 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02895815 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02453607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03081741 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02581007 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT04472247 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02191826 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT01414166 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01414166 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01414166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04088513 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT04128475 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT00458237 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05417503 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT03485638 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03485638 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01158573 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03073395 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01986010 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04495894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02700399 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03063762 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03594695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03594695 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT04570397 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT01903603 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT00926523 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT04219735 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04219735 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT04219735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04219735 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT04219735 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT06631352 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study NCT02888977 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02888977 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03858595 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02297373 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02876380 — Predictive Biomarker (PRD): KCNQ1 mRNA
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study NCT02876380 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study NCT02876380 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study NCT02212002 — Surrogate Endpoint (SUR): Bacterial count
Study NCT02598674 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04775420 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT00931268 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03263936 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01192984 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study NCT01030458 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01713231 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03732261 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03920956 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00968760 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00968760 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00968760 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03564301 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT01775865 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04092959 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00651209 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04666519 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT05166954 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02139371 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study NCT00325065 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT00827567 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00827567 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00306150 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00624728 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT01864798 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT01864798 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01864798 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT01567748 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03461237 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03762551 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT03762551 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study NCT04469621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03250676 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03048149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00093860 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03779035 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT03764605 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03764605 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT00001702 — Predictive Biomarker (PRD): SLC11A1 mRNA
Genes: SLC11A1; LSH; NRAMP; NRAMP1
Study NCT00001702 — Predictive Biomarker (PRD): FCGR2A
Genes: CD32; CD32A; IGFR2; CDw32; Fc-gamma-RIIa; FcgammaRIIa
Study NCT00001702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00001702 — Safety Biomarker (SAF): Interleukin 1
Study NCT00001702 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT05016648 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00681707 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02478320 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT01044654 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT01044654 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01044654 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01940822 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01444118 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02489019 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00341120 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT00341120 — Safety Biomarker (SAF): MTHFR
Study NCT03499418 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study NCT00634959 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT04551911 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02859948 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00771082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02776579 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01799317 — Predictive Biomarker (PRD): DMP1 mRNA
Genes: DMP1
Study NCT01799317 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00852566 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00852566 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01570283 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03947736 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01856361 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01856361 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT04309253 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04309253 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02021370 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01366092 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03185013 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03591289 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT01718470 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04156620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00133796 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04323241 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02043665 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study NCT02848911 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03365479 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT03365479 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03365479 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01019993 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03444207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00921089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03869203 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT02138942 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03535675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study NCT01626521 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03597685 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study NCT01112657 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT04553861 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01553851 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study NCT00006180 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01075776 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT00325637 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04613674 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04309318 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03776838 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01545336 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05314114 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01952730 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00614809 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03001219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01011075 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02171676 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02171676 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04078672 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01928043 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03071705 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03071705 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01521065 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01521065 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04572295 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04015726 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02882672 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06056466 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01156597 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00181025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01072591 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT01376817 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study NCT04324593 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04324593 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03480126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00004890 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00409318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02394730 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03211507 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study NCT00296634 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00006055 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02091141 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT03798665 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00124982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00124982 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03687385 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03370991 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03625427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03625427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03625427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04872816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04872816 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT01317667 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04273581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00004734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03480438 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03480438 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03480438 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03979820 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03323840 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05563324 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study NCT05563324 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study NCT05563324 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT05563324 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study NCT00911911 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00946192 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01719536 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02299765 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00367523 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04248829 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04248829 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05900193 — Predictive Biomarker (PRD): TAS1R3 mRNA
Genes: TAS1R3; T1R3; TR3
Study NCT02273687 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study NCT02664363 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00926913 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00091143 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03331666 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01462318 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01462318 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01462318 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01462318 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00666848 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00666848 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01528371 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03729076 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01335997 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06614374 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02439749 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00074737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00317421 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03462680 — Predictive Biomarker (PRD): HCAR2 mRNA
Genes: HCAR2; GPR109A; HCA2; HM74A; NIACR1
Study NCT03525743 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03245957 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT02387086 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04585997 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT04585997 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03538119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02072720 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02072720 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00106236 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01470716 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01470716 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02472119 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study NCT03956836 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT02084784 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT00414960 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105