TrialPanorama/TrialPanorama-database huggingface dataset:
Study 2158794 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21410393 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 21410393 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21410393 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21410393 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19589891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19589891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19589891 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16640927 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 8094001 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3618627 — Surrogate Endpoint (SUR): Serum triglycerides
Study 3618627 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3618627 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24965902 — Predictive Biomarker (PRD): AVPR2 mRNA
Genes: AVPR2; ADHR; DIR; DIR3; V2R
Study 24965902 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24965902 — Surrogate Endpoint (SUR): Blood pressure
Study 12799093 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12799093 — Surrogate Endpoint (SUR): Bone mineral density
Study 30139467 — Surrogate Endpoint (SUR): Serum creatinine
Study 18242045 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 18242045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18242045 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 29581214 — Surrogate Endpoint (SUR): Blood pressure
Study 29228792 — Surrogate Endpoint (SUR): Blood pressure
Study 25446887 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 25446887 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25446887 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 14597641 — Surrogate Endpoint (SUR): Blood pressure
Study 14597641 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1433163 — Surrogate Endpoint (SUR): Blood pressure
Study 22451180 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10561255 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8547958 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26153427 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18262190 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 18262190 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7749449 — Surrogate Endpoint (SUR): Blood pressure
Study 28095787 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 3055324 — Surrogate Endpoint (SUR): Blood pressure
Study 14999442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11372588 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11372588 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 22406102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20520854 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 31547675 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23510154 — Surrogate Endpoint (SUR): Blood pressure
Study 22161540 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24474383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18594845 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 18594845 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 18594845 — Predictive Biomarker (PRD): Microsatellite instability
Study 24549600 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 8591098 — Surrogate Endpoint (SUR): Blood pressure
Study 23815743 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11019835 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11019835 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 31095126 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22939108 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22939108 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21228265 — Surrogate Endpoint (SUR): Blood pressure
Study 17041825 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 23412930 — Surrogate Endpoint (SUR): Blood pressure
Study 30502778 — Surrogate Endpoint (SUR): Blood pressure
Study 22688551 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20346182 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20346182 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 12391340 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 8077370 — Surrogate Endpoint (SUR): Blood pressure
Study 27129012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27129012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10622275 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29263366 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24095896 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 12541094 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 11773991 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11773991 — Surrogate Endpoint (SUR): Blood pressure
Study 8556031 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 21888642 — Surrogate Endpoint (SUR): Blood pressure
Study 9059669 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 8337620 — Surrogate Endpoint (SUR): Blood pressure
Study 23945134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19965519 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27798513 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 3144009 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 3144009 — Surrogate Endpoint (SUR): Serum calcium
Study 28343938 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 20147742 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 20147742 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28884824 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10500310 — Safety Biomarker (SAF): MTHFR
Study 793562 — Surrogate Endpoint (SUR): Blood pressure
Study 27437665 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 26526421 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 17325591 — Surrogate Endpoint (SUR): Blood pressure
Study 10193369 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10193369 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 10193369 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30571173 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30571173 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22027612 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1325574 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 7625343 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29745885 — Predictive Biomarker (PRD): SOAT1 mRNA
Genes: SOAT1; ACACT; ACACT1; ACAT; ACAT1; SOAT; STAT
Study 16535996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25823544 — Surrogate Endpoint (SUR): Blood pressure
Study 19374211 — Surrogate Endpoint (SUR): Blood pressure
Study 9565434 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 29895557 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 25304132 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 12508269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8227233 — Surrogate Endpoint (SUR): Plasma ammonia
Study 30846557 — Safety Biomarker (SAF): Sodium/hydrogen exchanger 3
Genes: SLC9A3; NHE3
Study 30846557 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 25772512 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 12895189 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 8669404 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1989743 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26562047 — Surrogate Endpoint (SUR): Blood pressure
Study 22661508 — Safety Biomarker (SAF): Reactive oxygen species
Study 17326830 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23910069 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 21911782 — Predictive Biomarker (PRD): TLL1 mRNA
Genes: TLL1; TLL
Study 19918588 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12843164 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15541237 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9728845 — Surrogate Endpoint (SUR): Blood pressure
Study 30342297 — Surrogate Endpoint (SUR): Blood pressure
Study 28103904 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28103904 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21211686 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21211686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21211686 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19098618 — Surrogate Endpoint (SUR): Blood pressure
Study 12736880 — Surrogate Endpoint (SUR): Bone mineral density
Study 11003446 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11003446 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9087388 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21228786 — Surrogate Endpoint (SUR): Blood pressure
Study 10618674 — Surrogate Endpoint (SUR): Blood pressure
Study 6217577 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27999106 — Predictive Biomarker (PRD): GCG mRNA
Genes: GCG
Study 21255431 — Surrogate Endpoint (SUR): Blood pressure
Study 10914850 — Surrogate Endpoint (SUR): Bone mineral density
Study 8616076 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8616076 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8616076 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 17331860 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17331860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17331860 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29659631 — Surrogate Endpoint (SUR): Blood pressure
Study 18946456 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18946456 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27804268 — Surrogate Endpoint (SUR): Blood pressure
Study 18690343 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 10519936 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24770625 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 23175341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15787675 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 1846876 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1846876 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11300427 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 3632762 — Surrogate Endpoint (SUR): Blood pressure
Study 23306448 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 17002625 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3891357 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31118740 — Surrogate Endpoint (SUR): Blood pressure
Study 31118740 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27632268 — Surrogate Endpoint (SUR): Probing pocket depth
Study 20486273 — Surrogate Endpoint (SUR): Blood pressure
Study 10344043 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8452322 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8452322 — Surrogate Endpoint (SUR): Blood pressure
Study 8452322 — Surrogate Endpoint (SUR): Serum creatinine
Study 3539796 — Surrogate Endpoint (SUR): Blood pressure
Study 27471837 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 9519501 — Surrogate Endpoint (SUR): Blood pressure
Study 27573600 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27573600 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23546632 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23546632 — Safety Biomarker (SAF): Hyaluronic acid
Study 20887348 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20887348 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10391534 — Surrogate Endpoint (SUR): Bone mineral density
Study 25112083 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 23595264 — Surrogate Endpoint (SUR): Blood pressure
Study 16686840 — Predictive Biomarker (PRD): NAAA mRNA
Genes: NAAA; ASAHL; PLT
Study 21083385 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 21083385 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 16404415 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16404415 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 14974339 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9174684 — Surrogate Endpoint (SUR): Blood pressure
Study 20883231 — Surrogate Endpoint (SUR): Blood pressure
Study 7589016 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31670874 — Surrogate Endpoint (SUR): Blood pressure
Study 30156450 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25055558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30913216 — Surrogate Endpoint (SUR): Blood pressure
Study 23954381 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23954381 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 21865334 — Surrogate Endpoint (SUR): Blood pressure
Study 15522021 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7529507 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 7529507 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7529507 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 27464024 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9431480 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29506674 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 26201003 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 26201003 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9384462 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 30277538 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 29497960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26971164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16482467 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16440364 — Monitoring Biomarker (MOI): HBV DNA
Study 12580664 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12580664 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 8462205 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 23339958 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11216935 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29548848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29548848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29548848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29548848 — Safety Biomarker (SAF): BDNF
Study 27144849 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 27144849 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27144849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15546135 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 10420071 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 10420071 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7048338 — Surrogate Endpoint (SUR): Blood pressure
Study 17414235 — Predictive Biomarker (PRD): NE
Study 15808325 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25959989 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25959989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25959989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25959989 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19567540 — Surrogate Endpoint (SUR): Blood pressure
Study 15235317 — Surrogate Endpoint (SUR): Blood pressure
Study 3305460 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 3305460 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 26938813 — Surrogate Endpoint (SUR): Blood pressure
Study 17227729 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17227729 — Surrogate Endpoint (SUR): Bone mineral density
Study 17227729 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9376578 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31648883 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31648883 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31648883 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31333778 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31333778 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16507855 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24034178 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16822627 — Surrogate Endpoint (SUR): Blood pressure
Study 25054452 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 25054452 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 22243363 — Surrogate Endpoint (SUR): Serum potassium
Study 22243363 — Surrogate Endpoint (SUR): Blood pressure
Study 22243363 — Surrogate Endpoint (SUR): Serum creatinine
Study 17947724 — Predictive Biomarker (PRD): Hormone receptor
Study 9747912 — Surrogate Endpoint (SUR): Blood pressure
Study 8155207 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3076795 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28258828 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25881117 — Surrogate Endpoint (SUR): Blood pressure
Study 31558345 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31558345 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 31558345 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 31558345 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25886386 — Predictive Biomarker (PRD): EIF2AK3 mRNA
Genes: EIF2AK3; PEK; PERK
Study 25886386 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 25886386 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 25886386 — Predictive Biomarker (PRD): HYOU1 mRNA
Genes: HYOU1; GRP170; ORP150
Study 25886386 — Surrogate Endpoint (SUR): Serum creatinine
Study 19748656 — Predictive Biomarker (PRD): PTGDR mRNA
Genes: PTGDR
Study 14701888 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10099062 — Surrogate Endpoint (SUR): Blood pressure
Study 29231585 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29231585 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29231585 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16850002 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 12605431 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 10670908 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10670908 — Surrogate Endpoint (SUR): Serum creatinine
Study 10670908 — Surrogate Endpoint (SUR): Blood pressure
Study 16437736 — Surrogate Endpoint (SUR): Blood pressure
Study 30656404 — Surrogate Endpoint (SUR): Blood pressure
Study 7572757 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2344298 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30943832 — Surrogate Endpoint (SUR): Blood pressure
Study 26238707 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 22989086 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG