TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23483886 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20175428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20175428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12808485 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12808485 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27332677 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23630215 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 16934729 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 2522007 — Surrogate Endpoint (SUR): Blood pressure
Study 21956102 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21956102 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 21956102 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 7672138 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 30689707 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30689707 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30689707 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 30689707 — Predictive Biomarker (PRD): Hormone receptor
Study 30338823 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 20368558 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16269401 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27102200 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 27102200 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 27102200 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 27102200 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18087553 — Surrogate Endpoint (SUR): Blood pressure
Study 12473877 — Surrogate Endpoint (SUR): Blood pressure
Study 23952289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23952289 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16160626 — Predictive Biomarker (PRD): NE
Study 3303886 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25867913 — Surrogate Endpoint (SUR): Serum creatinine
Study 25867913 — Surrogate Endpoint (SUR): Bone mineral density
Study 19576015 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19576015 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16784647 — Surrogate Endpoint (SUR): Blood pressure
Study 18976766 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18976766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11223729 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 29353534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25592133 — Surrogate Endpoint (SUR): Bone mineral density
Study 21486976 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10873733 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9069163 — Surrogate Endpoint (SUR): Bone mineral density
Study 27321165 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 27321165 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 24801467 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22595386 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18035098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30630371 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30630371 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30630371 — Surrogate Endpoint (SUR): Blood pressure
Study 30630371 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14998784 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 11464450 — Surrogate Endpoint (SUR): Blood pressure
Study 11464450 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28783858 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21128816 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24420987 — Surrogate Endpoint (SUR): Blood pressure
Study 17661935 — Safety Biomarker (SAF): Hyaluronic acid
Study 9196163 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15927063 — Safety Biomarker (SAF): Hyaluronic acid
Study 19474284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 16636870 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16135178 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28969327 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 26255515 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15225901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15225901 — Safety Biomarker (SAF): Interleukin 1
Study 16054522 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 7554318 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 7554318 — Surrogate Endpoint (SUR): Serum calcium
Study 7554318 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 26791477 — Surrogate Endpoint (SUR): Blood pressure
Study 26791477 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17255748 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 9813512 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17533209 — Surrogate Endpoint (SUR): Blood pressure
Study 17533209 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 56903 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 29088099 — Predictive Biomarker (PRD): CCL24 mRNA
Genes: CCL24; MPIF2; SCYA24
Study 16145319 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 16145319 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 10089978 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7844665 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 22327087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22327087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18752692 — Surrogate Endpoint (SUR): Blood pressure
Study 16248242 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 11137328 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11137328 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29358194 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1283588 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1283588 — Surrogate Endpoint (SUR): Blood pressure
Study 1283588 — Surrogate Endpoint (SUR): Serum creatinine
Study 1283588 — Surrogate Endpoint (SUR): Serum potassium
Study 1283588 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1283588 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21555676 — Surrogate Endpoint (SUR): Blood pressure
Study 16710287 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3292710 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12496063 — Surrogate Endpoint (SUR): Serum testosterone
Study 2126420 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 11403352 — Surrogate Endpoint (SUR): Blood pressure
Study 8139992 — Surrogate Endpoint (SUR): Blood pressure
Study 3260641 — Surrogate Endpoint (SUR): Blood pressure
Study 15266074 — Safety Biomarker (SAF): Hypoxanthine-guanine phosphoribosyltransferase
Genes: HPRT1; HPRT
Study 8466006 — Surrogate Endpoint (SUR): Blood pressure
Study 17599425 — Surrogate Endpoint (SUR): Blood pressure
Study 15848601 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15848601 — Surrogate Endpoint (SUR): Serum creatinine
Study 10527967 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20150572 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11533541 — Surrogate Endpoint (SUR): Blood pressure
Study 8311374 — Surrogate Endpoint (SUR): Blood pressure
Study 26474870 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26474870 — Surrogate Endpoint (SUR): Blood pressure
Study 17956570 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 15997871 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15997871 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9385113 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18201432 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15716985 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 19335986 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 1525604 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26800231 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 24189107 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 17444589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7753339 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7753339 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31337172 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 26141305 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 11416689 — Surrogate Endpoint (SUR): Blood pressure
Study 31660848 — Predictive Biomarker (PRD): ELF3 mRNA
Genes: ELF3; ERT; ESX; JEN
Study 26004162 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 9216132 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7965851 — Surrogate Endpoint (SUR): Blood pressure
Study 25672163 — Surrogate Endpoint (SUR): Blood pressure
Study 21875410 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 21875410 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21875410 — Safety Biomarker (SAF): BDNF
Study 12938827 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 12938827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12938827 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8617896 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 9513798 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 31291977 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18345020 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18345020 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 12685616 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12685616 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9192926 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30103444 — Surrogate Endpoint (SUR): Blood pressure
Study 19874728 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 3896594 — Surrogate Endpoint (SUR): Blood pressure
Study 25273343 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25273343 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15767470 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9139273 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9139273 — Surrogate Endpoint (SUR): Blood pressure
Study 1660514 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 27842383 — Surrogate Endpoint (SUR): Serum creatinine
Study 25145934 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 21937805 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21937805 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17709451 — Safety Biomarker (SAF): MTHFR
Study 31104167 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 22990757 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22990757 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21724703 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 23091707 — Surrogate Endpoint (SUR): Blood pressure
Study 20570122 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12122096 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31455407 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 31455407 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 19963158 — Surrogate Endpoint (SUR): Blood pressure
Study 19963158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19963158 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15472177 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15472177 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16344495 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 16344495 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16344495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14736007 — Surrogate Endpoint (SUR): Blood pressure
Study 8651094 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6384250 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17035939 — Surrogate Endpoint (SUR): Blood pressure
Study 11381492 — Monitoring Biomarker (MOI): HBV DNA
Study 31477152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31477152 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2186055 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 31980913 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 19362013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19362013 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 19362013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19362013 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19362013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28624750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28624750 — Surrogate Endpoint (SUR): Blood pressure
Study 25503599 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 23240643 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23240643 — Surrogate Endpoint (SUR): Blood pressure
Study 21325105 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 2005918 — Surrogate Endpoint (SUR): Blood pressure
Study 16675962 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 8342828 — Surrogate Endpoint (SUR): Blood pressure
Study 16983910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6495747 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23290159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30215676 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 24099659 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7621460 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7621460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2220259 — Surrogate Endpoint (SUR): Bone mineral density
Study 26888911 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26888911 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9019842 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 6753454 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 31985629 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21865366 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21865366 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21865366 — Surrogate Endpoint (SUR): Blood pressure
Study 16932963 — Surrogate Endpoint (SUR): Bone mineral density
Study 14665875 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2693029 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19083444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19083444 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19083444 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16413056 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16413056 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 1630657 — Surrogate Endpoint (SUR): Blood pressure
Study 27887601 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 12489064 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 25994442 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 14742400 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14742400 — Surrogate Endpoint (SUR): Blood pressure
Study 11282447 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20734238 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20734238 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1669122 — Surrogate Endpoint (SUR): Blood pressure
Study 1669122 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31819948 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19808287 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12882847 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12882847 — Surrogate Endpoint (SUR): Blood pressure
Study 8791245 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 1463179 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 6388424 — Surrogate Endpoint (SUR): Blood pressure
Study 18086056 — Safety Biomarker (SAF): Hyaluronic acid
Study 7820712 — Surrogate Endpoint (SUR): Blood pressure
Study 25478757 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 22050797 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22050797 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 3531226 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 22389254 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 20039397 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15777291 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15777291 — Surrogate Endpoint (SUR): Blood pressure
Study 15201414 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 2258583 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27840326 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25709055 — Surrogate Endpoint (SUR): Blood pressure
Study 25262253 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30361325 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 27030088 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18587249 — Surrogate Endpoint (SUR): Serum sodium
Study 1760424 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24123319 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 9823014 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15197501 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11307261 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8458598 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 8458598 — Surrogate Endpoint (SUR): Blood pressure
Study 30666823 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 30020423 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 3244794 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 17548076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7735594 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23314272 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25043459 — Surrogate Endpoint (SUR): Bone mineral density
Study 3124899 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3124899 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28881387 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 28881387 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 10764905 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9284855 — Surrogate Endpoint (SUR): Blood pressure
Study 28400368 — Surrogate Endpoint (SUR): Serum creatinine
Study 25198310 — Surrogate Endpoint (SUR): Bone mineral density
Study 19671306 — Surrogate Endpoint (SUR): Blood pressure
Study 19671306 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19671306 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7251221 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23328162 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17491099 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 21388309 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21388309 — Surrogate Endpoint (SUR): Blood pressure
Study 21388309 — Surrogate Endpoint (SUR): Serum creatinine
Study 24306695 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 21880996 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER