TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29554385 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17631083 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7852209 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 16292319 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9316956 — Surrogate Endpoint (SUR): Blood pressure
Study 8398293 — Surrogate Endpoint (SUR): Serum calcium
Study 23419552 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 21366899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19535243 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 17513798 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11887802 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11887802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11887802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11887802 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9512112 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9512112 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9512112 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 9512112 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16907931 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16907931 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28541810 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24754265 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 20613498 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19010201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19010201 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30248152 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15968293 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 223601 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 223601 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30630567 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11334202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11334202 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27871827 — Safety Biomarker (SAF): Reactive oxygen species
Study 19727884 — Surrogate Endpoint (SUR): Blood pressure
Study 15114551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23569370 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20331687 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 20331687 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31949084 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 12411798 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12411798 — Surrogate Endpoint (SUR): Blood pressure
Study 31335865 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23759203 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 19945297 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16823366 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16508259 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29258678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22872988 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22872988 — Surrogate Endpoint (SUR): Blood pressure
Study 6336719 — Surrogate Endpoint (SUR): Blood pressure
Study 3289645 — Surrogate Endpoint (SUR): Blood pressure
Study 3289645 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26325387 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12477503 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12477503 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10325282 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31133061 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 26341706 — Monitoring Biomarker (MOI): Procalcitonin
Study 17088002 — Surrogate Endpoint (SUR): Blood pressure
Study 15178687 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 8595925 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 8595925 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 365249 — Surrogate Endpoint (SUR): Blood pressure
Study 31859246 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 31859246 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31859246 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31859246 — Predictive Biomarker (PRD): Hormone receptor
Study 19001447 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16882745 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 15172401 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 9205920 — Surrogate Endpoint (SUR): Probing pocket depth
Study 2450244 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2450244 — Surrogate Endpoint (SUR): Blood pressure
Study 25382325 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19033608 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12052450 — Surrogate Endpoint (SUR): Bone mineral density
Study 9822138 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9822138 — Surrogate Endpoint (SUR): Blood pressure
Study 23596814 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18930251 — Safety Biomarker (SAF): IL-6 and IL-10
Study 11728663 — Predictive Biomarker (PRD): PLN mRNA
Genes: PLN; PLB
Study 3666688 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 19332196 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19332196 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30587468 — Surrogate Endpoint (SUR): Blood pressure
Study 26602699 — Surrogate Endpoint (SUR): Blood pressure
Study 20940450 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17536194 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15180168 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 15180168 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3386506 — Surrogate Endpoint (SUR): Blood pressure
Study 22218933 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 17347579 — Surrogate Endpoint (SUR): Blood pressure
Study 1895263 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19406269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19406269 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 19406269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19406269 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 15149341 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11144997 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20874769 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20874769 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 1461956 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21947428 — Surrogate Endpoint (SUR): Blood pressure
Study 9149200 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 26979520 — Predictive Biomarker (PRD): SLC29A4 mRNA
Genes: SLC29A4; ENT4; PMAT; PSEC0113
Study 22344611 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 15289797 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11135086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9853274 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31852749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-34a
Genes: MIR34A
Study 31852749 — Safety Biomarker (SAF): miR-133b
Genes: MIR133B
Study 28486474 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 23278466 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 17461851 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15187512 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 15187512 — Surrogate Endpoint (SUR): Serum creatinine
Study 30337746 — Surrogate Endpoint (SUR): Blood pressure
Study 20691837 — Surrogate Endpoint (SUR): Blood pressure
Study 18292286 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 12634948 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28864226 — Surrogate Endpoint (SUR): Serum creatinine
Study 15170026 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7663801 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17103437 — Surrogate Endpoint (SUR): Bone mineral density
Study 14688492 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14688492 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10670837 — Predictive Biomarker (PRD): NFKBIA
Genes: IKBA; MAD-3; IkappaBalpha
Study 27866772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17417133 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11485110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11485110 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 21311063 — Surrogate Endpoint (SUR): Blood pressure
Study 21311063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17418554 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15145911 — Surrogate Endpoint (SUR): Blood pressure
Study 23488491 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23488491 — Surrogate Endpoint (SUR): Blood pressure
Study 16454834 — Monitoring Biomarker (MOI): HBV DNA
Study 15237079 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 15622016 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 2899511 — Surrogate Endpoint (SUR): Serum calcium
Study 29617504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29617504 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 27807041 — Surrogate Endpoint (SUR): Blood pressure
Study 23748506 — Surrogate Endpoint (SUR): Blood pressure
Study 23748506 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1349028 — Surrogate Endpoint (SUR): Blood pressure
Study 31475572 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31475572 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31475572 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21105887 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28024930 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 28024930 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23866314 — Safety Biomarker (SAF): RYR1
Genes: RYR; PPP1R137
Study 23866314 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11096461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3533568 — Surrogate Endpoint (SUR): Blood pressure
Study 28914562 — Surrogate Endpoint (SUR): Blood pressure
Study 27600181 — Surrogate Endpoint (SUR): Blood pressure
Study 15816573 — Surrogate Endpoint (SUR): Blood pressure
Study 10619585 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 26050650 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 21610711 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19628194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19628194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10333035 — Surrogate Endpoint (SUR): Blood pressure
Study 19898645 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26234623 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15823293 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2650700 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 69143 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8587456 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 8587456 — Surrogate Endpoint (SUR): Blood pressure
Study 28772048 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 28772048 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 23781136 — Monitoring Biomarker (MOI): Procalcitonin
Study 21543343 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 11773285 — Predictive Biomarker (PRD): Hormone receptor
Study 8294090 — Surrogate Endpoint (SUR): Plasma ammonia
Study 22643350 — Monitoring Biomarker (MOI): HBV DNA
Study 18514770 — Predictive Biomarker (PRD): UBC mRNA
Genes: UBC
Study 10868866 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30570529 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 30570529 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 30570529 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 25415777 — Surrogate Endpoint (SUR): Blood pressure
Study 2177614 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2177614 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19756557 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2964548 — Surrogate Endpoint (SUR): Blood pressure
Study 31526307 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31526307 — Surrogate Endpoint (SUR): Blood pressure
Study 11136953 — Surrogate Endpoint (SUR): Blood pressure
Study 9630383 — Surrogate Endpoint (SUR): Plasma sitosterol and campesterol
Study 19886856 — Surrogate Endpoint (SUR): Blood pressure
Study 19886856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7898078 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16022955 — Predictive Biomarker (PRD): ETV3 mRNA
Genes: ETV3; METS; PE1
Study 20308916 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 18803987 — Surrogate Endpoint (SUR): Blood pressure
Study 15994073 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7758229 — Surrogate Endpoint (SUR): Bone mineral density
Study 10403690 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 30896819 — Predictive Biomarker (PRD): DIAPH2 mRNA
Genes: DIAPH2; DIA
Study 30896819 — Predictive Biomarker (PRD): FOXN3 mRNA
Genes: FOXN3; C14orf116; CHES1
Study 30896819 — Predictive Biomarker (PRD): RHPN1 mRNA
Genes: RHPN1; KIAA1929
Study 30896819 — Predictive Biomarker (PRD): MEG3
Study 30701884 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 24686347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11327625 — Surrogate Endpoint (SUR): Blood pressure
Study 9040452 — Surrogate Endpoint (SUR): Blood pressure
Study 3217992 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 3217992 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 30926293 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 17992639 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 7551664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15608388 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 2565117 — Surrogate Endpoint (SUR): Blood pressure
Study 28856913 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 18079261 — Predictive Biomarker (PRD): SLC16A4 mRNA
Genes: SLC16A4; MCT4; MCT5
Study 18079261 — Predictive Biomarker (PRD): MCTS1 mRNA
Genes: MCTS1; MCT1
Study 3308702 — Surrogate Endpoint (SUR): Blood pressure
Study 29694685 — Surrogate Endpoint (SUR): Bone mineral density
Study 12655794 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12655794 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7671437 — Surrogate Endpoint (SUR): Blood pressure
Study 6776858 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23305576 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 14986257 — Safety Biomarker (SAF): Interleukin 1
Study 9203756 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 28417527 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26605836 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11972594 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 9654837 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 28676038 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26260553 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 10713659 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8874676 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 22659998 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 18634770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18634770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7579383 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31035472 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22302614 — Surrogate Endpoint (SUR): Bone mineral density
Study 21462082 — Predictive Biomarker (PRD): GMCL2 mRNA
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 16433867 — Surrogate Endpoint (SUR): Blood pressure
Study 15569238 — Predictive Biomarker (PRD): CD109 mRNA
Genes: CD109; CPAMD7
Study 11061579 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17971487 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 17971487 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 12756503 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 8678062 — Surrogate Endpoint (SUR): Serum sodium
Study 29553033 — Surrogate Endpoint (SUR): Blood pressure
Study 29084686 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 29084686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29084686 — Surrogate Endpoint (SUR): Blood pressure
Study 9714485 — Surrogate Endpoint (SUR): Blood pressure
Study 14616414 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 14616414 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 14616414 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3883170 — Surrogate Endpoint (SUR): Blood pressure
Study 3883170 — Surrogate Endpoint (SUR): Serum potassium
Study 22801564 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17392729 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 17392729 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 17392729 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16334158 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 12468959 — Surrogate Endpoint (SUR): Serum creatinine
Study 9382122 — Surrogate Endpoint (SUR): Bone mineral density
Study 1550171 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1550171 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22943970 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17332965 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 18800460 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21727232 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 14715339 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24747297 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 22089105 — Surrogate Endpoint (SUR): Blood pressure
Study 22089105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17233848 — Predictive Biomarker (PRD): Liver iron
Study 17233848 — Surrogate Endpoint (SUR): Serum creatinine
Study 1807007 — Surrogate Endpoint (SUR): Blood pressure
Study 31647384 — Surrogate Endpoint (SUR): Blood pressure
Study 30289287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1