TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT06156722 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00399165 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02834988 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT02897570 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT02852317 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02852317 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02852317 — Safety Biomarker (SAF): BDNF
Study NCT00248183 — Predictive Biomarker (PRD): PRX mRNA
Genes: PRX; KIAA1620
Study NCT00248183 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03664999 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT01140126 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00053495 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01361425 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02626832 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT03698877 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01226199 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study NCT01226199 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT02804087 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04857203 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04324736 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03266692 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT00874328 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT04842591 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02769039 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT02448407 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02058680 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00507143 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study NCT03975699 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01579136 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01935882 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT04215107 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT06084377 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT01933932 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03016052 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT01762852 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03134716 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT03134716 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study NCT00357903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03820895 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT00700271 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04209725 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00001413 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04616989 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03650127 — Predictive Biomarker (PRD): PDIA6 mRNA
Genes: PDIA6; ERP5; P5; TXNDC7
Study NCT00756613 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05462535 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01977859 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04287582 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00719472 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04129463 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT01610115 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01469611 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01946230 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study NCT01955421 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03688594 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00960349 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT02549833 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT00742092 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study NCT02756754 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00896675 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01919983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01919983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01699438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00085202 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00085202 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study NCT02132429 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00775190 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00595114 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study NCT00894673 — Predictive Biomarker (PRD): TTPA mRNA
Genes: TTPA; TPP1
Study NCT00084513 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03673501 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01685957 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04527211 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04271397 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT04271397 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04466982 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02979665 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02131506 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02338271 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01506570 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02817009 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03535350 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT02386657 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT01312714 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT01312714 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00951730 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04623242 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study NCT02913664 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02695563 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT03995108 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00254384 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03035357 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT03343054 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03343054 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03169660 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03169660 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06433336 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01409941 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01409941 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04277338 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04277338 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01082068 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study NCT01082068 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01082068 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00885170 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04639739 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02282098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02282098 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02718144 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00971815 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01364844 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03253146 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT02759367 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02759367 — Surrogate Endpoint (SUR): Serum potassium
Study NCT01944514 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00179309 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00179309 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00179309 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT04254172 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01148654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02574507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03095963 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02369887 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02369887 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00346697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03463928 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04341207 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03547401 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00684216 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01940796 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT01672671 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02112071 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03232476 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03544177 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05396742 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT04110847 — Predictive Biomarker (PRD): GPR143 mRNA
Genes: GPR143; OA1
Study NCT04079270 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01418690 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01842217 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT01842217 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01598506 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00265135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01735331 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01941407 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02517775 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01956838 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT00976560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01227993 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT01339052 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01663103 — Safety Biomarker (SAF): Interleukin 1
Study NCT00564044 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study NCT00811135 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04032093 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02149043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03099330 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01297127 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02305355 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03270501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02360878 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02147405 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02542722 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01834105 — Predictive Biomarker (PRD): CLCF1 mRNA
Genes: CLCF1; BSF3; CLC; NNT1
Study NCT01834105 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT01834105 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study NCT00409851 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03744845 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04231994 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03370432 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT03370432 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study NCT03068585 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01707199 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study NCT01707199 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study NCT00429858 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT00429858 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study NCT00429858 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study NCT00429858 — Predictive Biomarker (PRD): SLC28A1 mRNA
Genes: SLC28A1; CNT1
Study NCT00429858 — Predictive Biomarker (PRD): CNT3 mRNA
Genes: SLC28A3; CNT3
Study NCT00429858 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT03616938 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03389035 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01903421 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01903421 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00825526 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02750163 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04350710 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05787405 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00438295 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03761368 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT02999204 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02873351 — Predictive Biomarker (PRD): GPR143 mRNA
Genes: GPR143; OA1
Study NCT02873351 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study NCT02873351 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01007656 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01007656 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01237769 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study NCT01237769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01237769 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01237769 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT01237769 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01237769 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04385290 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01472497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01375270 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03821090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03821090 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT04462627 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT05399186 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04106752 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02428296 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02428296 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02172586 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01109784 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03361397 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01127724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00769535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00421824 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02170467 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01619306 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01619306 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02102763 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00299832 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03803098 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01297335 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02070614 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01931293 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study NCT01931293 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study NCT03618563 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT02264184 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT03527459 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT04626908 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04626908 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT01872390 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01692301 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01426828 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT02905565 — Predictive Biomarker (PRD): NUBP1 mRNA
Genes: NUBP1; NBP; NBP1
Study NCT03001869 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04465916 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT02228369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03664414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01078155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01078155 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04659460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04659460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04659460 — Safety Biomarker (SAF): Interleukin 1
Study NCT04659460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04659460 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT02116166 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT02116166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02116166 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study NCT02116166 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT02116166 — Predictive Biomarker (PRD): SLC39A14 mRNA
Genes: SLC39A14; KIAA0062; ZIP14
Study NCT02116166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02116166 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT04303936 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT01242449 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03285750 — Predictive Biomarker (PRD): FFAR4 mRNA
Genes: FFAR4; GPR120; GPR129; O3FAR1; PGR4
Study NCT01490697 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01031745 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02072031 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT02072031 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study NCT00776607 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00354328 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02627820 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT00712907 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00248040 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00148213 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00779662 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD