TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17300851 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 11316974 — Surrogate Endpoint (SUR): Serum testosterone
Study 9396403 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20428722 — Surrogate Endpoint (SUR): Blood pressure
Study 12551868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1676617 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 27321385 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28719765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24279607 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23095869 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19235040 — Predictive Biomarker (PRD): CCND2 mRNA
Genes: CCND2
Study 19235040 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 2146870 — Surrogate Endpoint (SUR): Blood pressure
Study 11588535 — Surrogate Endpoint (SUR): Blood pressure
Study 9681776 — Surrogate Endpoint (SUR): Blood pressure
Study 16940981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10569685 — Surrogate Endpoint (SUR): Blood pressure
Study 21960073 — Surrogate Endpoint (SUR): Blood pressure
Study 12771613 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12771613 — Surrogate Endpoint (SUR): Blood pressure
Study 10688831 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10688831 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29905646 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21084620 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 16355622 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16355622 — Surrogate Endpoint (SUR): Serum creatinine
Study 11279324 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18843927 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 16137437 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10915232 — Surrogate Endpoint (SUR): Blood pressure
Study 27974950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20194883 — Surrogate Endpoint (SUR): Blood pressure
Study 11896513 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7860418 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 913294 — Surrogate Endpoint (SUR): Blood pressure
Study 6782605 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 27336726 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 27336726 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27336726 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27336726 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study 27336726 — Predictive Biomarker (PRD): CCND2 mRNA
Genes: CCND2
Study 27336726 — Predictive Biomarker (PRD): CCND3 mRNA
Genes: CCND3
Study 27336726 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCNE1 mRNA
Genes: CCNE1; CCNE
Study 27336726 — Predictive Biomarker (PRD): Hormone receptor
Study 27336726 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 20417445 — Surrogate Endpoint (SUR): Blood pressure
Study 22197676 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22197676 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 8596594 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24928217 — Surrogate Endpoint (SUR): Blood pressure
Study 20586550 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 19014790 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12023993 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 12023993 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 1838079 — Surrogate Endpoint (SUR): Bone mineral density
Study 1838079 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 1838079 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1838079 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23637556 — Surrogate Endpoint (SUR): Blood pressure
Study 16678551 — Surrogate Endpoint (SUR): Blood pressure
Study 11295031 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24458199 — Surrogate Endpoint (SUR): Bone mineral density
Study 21435695 — Surrogate Endpoint (SUR): Serum uric acid
Study 21435695 — Surrogate Endpoint (SUR): Serum creatinine
Study 16814206 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23082801 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19246893 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 14691439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11720197 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2577461 — Surrogate Endpoint (SUR): Blood pressure
Study 19666939 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 11288049 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8307554 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 3709026 — Surrogate Endpoint (SUR): Blood pressure
Study 31713941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31713941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20367777 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 11950104 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 760698 — Surrogate Endpoint (SUR): Serum calcium
Study 21893621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21893621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21893621 — Surrogate Endpoint (SUR): Blood pressure
Study 8435262 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8435262 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8435262 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 27756037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27756037 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24142329 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 16868539 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30535651 — Surrogate Endpoint (SUR): Blood pressure
Study 9562008 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9562008 — Surrogate Endpoint (SUR): Blood pressure
Study 25586095 — Predictive Biomarker (PRD): HMGA1 mRNA
Genes: HMGA1; HMGIY
Study 22476908 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 16518702 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 10413279 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10413279 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8689462 — Safety Biomarker (SAF): Hyaluronic acid
Study 698165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21191143 — Predictive Biomarker (PRD): ABL2 mRNA
Genes: ABL2; ABLL; ARG
Study 21191143 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15235055 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 14564675 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14564675 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10670160 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 7474675 — Surrogate Endpoint (SUR): Blood pressure
Study 7474675 — Surrogate Endpoint (SUR): Serum creatinine
Study 29670279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29670279 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21063429 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19302900 — Surrogate Endpoint (SUR): Bone mineral density
Study 11150007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10049522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27402475 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9264147 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9264147 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9264147 — Surrogate Endpoint (SUR): Blood pressure
Study 3731824 — Surrogate Endpoint (SUR): Blood pressure
Study 25008861 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 11849656 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11849656 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 30249190 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 22383668 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 3655856 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24172209 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 20155988 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7237927 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31779672 — Surrogate Endpoint (SUR): Blood pressure
Study 17671114 — Predictive Biomarker (PRD): RAMP2 mRNA
Genes: RAMP2
Study 17671114 — Predictive Biomarker (PRD): EFEMP1 mRNA
Genes: EFEMP1; FBLN3; FBNL
Study 15310347 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7983882 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25370899 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 25370899 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 25370899 — Predictive Biomarker (PRD): XRCC3 mRNA
Genes: XRCC3
Study 25370899 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 25370899 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 25370899 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study 25370899 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 1488874 — Surrogate Endpoint (SUR): Blood pressure
Study 10453752 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10453752 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 16636029 — Surrogate Endpoint (SUR): Blood pressure
Study 10197572 — Surrogate Endpoint (SUR): Bone mineral density
Study 30985546 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29126030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29126030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14688176 — Surrogate Endpoint (SUR): Bone mineral density
Study 11207037 — Safety Biomarker (SAF): 51Cr-EDTA
Study 11207037 — Surrogate Endpoint (SUR): Serum creatinine
Study 8373942 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 29146401 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29146401 — Predictive Biomarker (PRD): Hormone receptor
Study 23053125 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 17005084 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 17005084 — Surrogate Endpoint (SUR): Serum uric acid
Study 31379301 — Surrogate Endpoint (SUR): Blood pressure
Study 18261733 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 18261733 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 18261733 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17001217 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17001217 — Surrogate Endpoint (SUR): Blood pressure
Study 10852328 — Surrogate Endpoint (SUR): Bone mineral density
Study 3897470 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 15479889 — Surrogate Endpoint (SUR): Bone mineral density
Study 31931532 — Surrogate Endpoint (SUR): Blood pressure
Study 21624142 — Surrogate Endpoint (SUR): Blood pressure
Study 10678548 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10678548 — Surrogate Endpoint (SUR): Serum creatinine
Study 10678548 — Surrogate Endpoint (SUR): Serum potassium
Study 10678548 — Surrogate Endpoint (SUR): Blood pressure
Study 9213834 — Surrogate Endpoint (SUR): Blood pressure
Study 25783468 — Surrogate Endpoint (SUR): Bone mineral density
Study 21621673 — Surrogate Endpoint (SUR): Blood pressure
Study 16728716 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 1845606 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28668664 — Surrogate Endpoint (SUR): Blood pressure
Study 17563127 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15339848 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 9675564 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 9675564 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 2166142 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 364409 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31983513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31983513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15145926 — Surrogate Endpoint (SUR): Bone mineral density
Study 8059021 — Surrogate Endpoint (SUR): Serum creatinine
Study 8059021 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28248690 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 9742523 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31945399 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 19536906 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 3041940 — Surrogate Endpoint (SUR): Serum calcium
Study 31486166 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 31486166 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 9117226 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8418238 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24955611 — Surrogate Endpoint (SUR): Blood pressure
Study 10100174 — Surrogate Endpoint (SUR): Blood pressure
Study 10100174 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10100174 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1687055 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 16089148 — Surrogate Endpoint (SUR): Blood pressure
Study 23362725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23362725 — Surrogate Endpoint (SUR): Blood pressure
Study 23362725 — Surrogate Endpoint (SUR): Serum uric acid
Study 17076614 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 30650565 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 24089589 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 24089589 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28073680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26196407 — Surrogate Endpoint (SUR): Blood pressure
Study 9681342 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28924143 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 23892298 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21820095 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17527093 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17527093 — Surrogate Endpoint (SUR): Bone mineral density
Study 27737930 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 23347858 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 21315003 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 21315003 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21315003 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7992907 — Surrogate Endpoint (SUR): Blood pressure
Study 2563454 — Safety Biomarker (SAF): Reactive oxygen species
Study 17615257 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 16131584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31299857 — Predictive Biomarker (PRD): MZB1 mRNA
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 23589670 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23589670 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 23589670 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 27270245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27270245 — Safety Biomarker (SAF): Interleukin 1
Study 23931876 — Surrogate Endpoint (SUR): Serum creatinine
Study 12511716 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11244702 — Surrogate Endpoint (SUR): Blood pressure
Study 1519232 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1519232 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31860830 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22078979 — Surrogate Endpoint (SUR): Blood pressure
Study 29064626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29064626 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22408272 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 19597422 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19597422 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11409425 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 7920126 — Surrogate Endpoint (SUR): Blood pressure
Study 11642634 — Monitoring Biomarker (MOI): HBV DNA
Study 2646266 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 2646266 — Surrogate Endpoint (SUR): Serum testosterone
Study 28403619 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11740797 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30298552 — Surrogate Endpoint (SUR): Blood pressure
Study 24022566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24022566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24022566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22872030 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22872030 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22872030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20404219 — Surrogate Endpoint (SUR): Blood pressure
Study 12439084 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30939531 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21836029 — Surrogate Endpoint (SUR): Serum sodium
Study 25951697 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18060022 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 28244952 — Surrogate Endpoint (SUR): Blood pressure
Study 9883467 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 29344387 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 31126123 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 18220290 — Monitoring Biomarker (MOI): HBV DNA
Study 14583678 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 9383184 — Surrogate Endpoint (SUR): Blood pressure
Study 9383184 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21147867 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12324670 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1701802 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20002088 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 20002088 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20002088 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20002088 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30551161 — Surrogate Endpoint (SUR): Serum creatinine
Study 26347545 — Surrogate Endpoint (SUR): Blood pressure
Study 23596809 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22005564 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 22005564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17717030 — Surrogate Endpoint (SUR): Serum calcium
Study 12535831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30449838 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 8656557 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study 6137970 — Surrogate Endpoint (SUR): Blood pressure
Study 28252842 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 9362354 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1412680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29238988 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20207331 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19143194 — Surrogate Endpoint (SUR): Blood pressure
Study 31152545 — Surrogate Endpoint (SUR): Blood pressure
Study 21536989 — Surrogate Endpoint (SUR): Blood pressure