TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12618690 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10587038 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 22441345 — Surrogate Endpoint (SUR): Blood pressure
Study 9849704 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9849704 — Surrogate Endpoint (SUR): Blood pressure
Study 2570283 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27833860 — Surrogate Endpoint (SUR): Blood pressure
Study 23228097 — Surrogate Endpoint (SUR): Serum creatinine
Study 30907141 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 16981140 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16981140 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15287931 — Surrogate Endpoint (SUR): Blood pressure
Study 15287931 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8215644 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24748301 — Predictive Biomarker (PRD): FSTL1 mRNA
Genes: FSTL1; FRP
Study 8985227 — Safety Biomarker (SAF): IL-6 and IL-10
Study 24299914 — Surrogate Endpoint (SUR): Blood pressure
Study 9252849 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 9252849 — Surrogate Endpoint (SUR): Bone mineral density
Study 21700892 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 17509587 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 29216361 — Predictive Biomarker (PRD): Hormone receptor
Study 18301060 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16463698 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16463698 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12185552 — Surrogate Endpoint (SUR): Blood pressure
Study 29017796 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 29017796 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 29017796 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 29017796 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15226327 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16550734 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17588581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17588581 — Surrogate Endpoint (SUR): Blood pressure
Study 17588581 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8676836 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 8676836 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1335008 — Surrogate Endpoint (SUR): Blood pressure
Study 24657333 — Surrogate Endpoint (SUR): Serum calcium
Study 9389427 — Surrogate Endpoint (SUR): Blood pressure
Study 17711378 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12195238 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23958526 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23958526 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15201620 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28715944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23013513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23013513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16402128 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 11075741 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11075741 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16722841 — Surrogate Endpoint (SUR): Blood pressure
Study 27496336 — Surrogate Endpoint (SUR): Serum calcium
Study 27496336 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 25488826 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 25488826 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 25488826 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 2890669 — Surrogate Endpoint (SUR): Blood pressure
Study 30103679 — Surrogate Endpoint (SUR): Blood pressure
Study 11834535 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24898552 — Surrogate Endpoint (SUR): Blood pressure
Study 19170164 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3153710 — Surrogate Endpoint (SUR): Blood pressure
Study 31822251 — Surrogate Endpoint (SUR): Blood pressure
Study 18226399 — Predictive Biomarker (PRD): DDAH1 mRNA
Genes: DDAH1; DDAH
Study 31533906 — Surrogate Endpoint (SUR): Blood pressure
Study 31533906 — Surrogate Endpoint (SUR): Serum potassium
Study 7752866 — Safety Biomarker (SAF): Reactive oxygen species
Study 31683132 — Surrogate Endpoint (SUR): Blood pressure
Study 16838645 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9269644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9269644 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 6125171 — Surrogate Endpoint (SUR): Blood pressure
Study 6125171 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30014863 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 25199060 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 3396298 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31495881 — Surrogate Endpoint (SUR): Serum creatinine
Study 24355439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24355439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24355439 — Safety Biomarker (SAF): Interleukin 12
Study 24355439 — Safety Biomarker (SAF): Interleukin 1
Study 24355439 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18337713 — Surrogate Endpoint (SUR): Blood pressure
Study 12846338 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8689812 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30648627 — Surrogate Endpoint (SUR): Bone mineral density
Study 15084372 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15894835 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 15894835 — Surrogate Endpoint (SUR): Blood pressure
Study 11747848 — Surrogate Endpoint (SUR): Serum creatinine
Study 8405011 — Surrogate Endpoint (SUR): Blood pressure
Study 30405211 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 30405211 — Safety Biomarker (SAF): CDA
Genes: CDD
Study 20031461 — Predictive Biomarker (PRD): RPLP0 mRNA
Genes: RPLP0
Study 27373900 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 19453623 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30041682 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23769603 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 20492042 — Surrogate Endpoint (SUR): Blood pressure
Study 21411615 — Surrogate Endpoint (SUR): Blood pressure
Study 16617567 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16617567 — Predictive Biomarker (PRD): Hormone receptor
Study 28448457 — Surrogate Endpoint (SUR): Bone mineral density
Study 24125113 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 10519494 — Surrogate Endpoint (SUR): Blood pressure
Study 31399091 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 31399091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23782920 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 23782920 — Surrogate Endpoint (SUR): Blood pressure
Study 18588512 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18588512 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 11729708 — Surrogate Endpoint (SUR): Serum sodium
Study 2887189 — Surrogate Endpoint (SUR): Blood pressure
Study 30406067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16619561 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16619561 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 618711 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 618711 — Surrogate Endpoint (SUR): Blood pressure
Study 16296399 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 15845796 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 10596916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10596916 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28122382 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 21111590 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19379147 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9497572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31541565 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 20399996 — Surrogate Endpoint (SUR): Blood pressure
Study 18061070 — Safety Biomarker (SAF): Reactive oxygen species
Study 27394187 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2122630 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29902418 — Surrogate Endpoint (SUR): Blood pressure
Study 24341324 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23312888 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23312888 — Predictive Biomarker (PRD): Hormone receptor
Study 15722700 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 28488924 — Surrogate Endpoint (SUR): Blood pressure
Study 22860302 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22860302 — Surrogate Endpoint (SUR): Blood pressure
Study 18467544 — Surrogate Endpoint (SUR): Bone mineral density
Study 6861446 — Surrogate Endpoint (SUR): Serum potassium
Study 30796027 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22647753 — Surrogate Endpoint (SUR): Blood pressure
Study 22647753 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17385022 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 10215706 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8977914 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29517132 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 24059649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24059649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24059649 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28724652 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 21078200 — Surrogate Endpoint (SUR): Blood pressure
Study 14550442 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23651425 — Surrogate Endpoint (SUR): Serum testosterone
Study 18979716 — Surrogate Endpoint (SUR): Blood pressure
Study 18979716 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10764418 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 1611639 — Surrogate Endpoint (SUR): Blood pressure
Study 24185044 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 24185044 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17504798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16248466 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 369991 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 31215037 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30920602 — Surrogate Endpoint (SUR): Blood pressure
Study 30920602 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30920602 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17204591 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 17204591 — Surrogate Endpoint (SUR): Blood pressure
Study 21722959 — Predictive Biomarker (PRD): KCNN3 mRNA
Genes: KCNN3; K3
Study 19155978 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 16467647 — Surrogate Endpoint (SUR): Blood pressure
Study 8986684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28737273 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 16087057 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3929067 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 29450689 — Surrogate Endpoint (SUR): Blood pressure
Study 26699690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26699690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15885641 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 10378632 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27342507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22248153 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 10800818 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 22473769 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12527599 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30725040 — Surrogate Endpoint (SUR): Blood pressure
Study 26891420 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26891420 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 26891420 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26891420 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 18794027 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6142700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 31166681 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 31166681 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 23507474 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20732932 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20732932 — Predictive Biomarker (PRD): Hormone receptor
Study 12682802 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18430173 — Safety Biomarker (SAF): Hyaluronic acid
Study 12552211 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10532441 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 26474055 — Surrogate Endpoint (SUR): Blood pressure
Study 26474055 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8231773 — Surrogate Endpoint (SUR): Blood pressure
Study 25009220 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 25009220 — Predictive Biomarker (PRD): EIF2AK3 mRNA
Genes: EIF2AK3; PEK; PERK
Study 25009220 — Predictive Biomarker (PRD): ATF6 mRNA
Genes: ATF6
Study 25009220 — Predictive Biomarker (PRD): ATF4 mRNA
Genes: ATF4; CREB2; TXREB
Study 25009220 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 15608524 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 2401128 — Surrogate Endpoint (SUR): Blood pressure
Study 19568199 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19568199 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17584560 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11160540 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7853324 — Surrogate Endpoint (SUR): Blood pressure
Study 30342298 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30342298 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 30342298 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30342298 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23978276 — Surrogate Endpoint (SUR): Blood pressure
Study 2065534 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 3909842 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3909842 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9003465 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 9003465 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9003465 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 22962863 — Surrogate Endpoint (SUR): Blood pressure
Study 22744704 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 29604186 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 27709863 — Safety Biomarker (SAF): Hyaluronic acid
Study 28690011 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28690011 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12958322 — Surrogate Endpoint (SUR): Blood pressure
Study 29268948 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26788432 — Surrogate Endpoint (SUR): Blood pressure
Study 12834935 — Surrogate Endpoint (SUR): Blood pressure
Study 20860572 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19083390 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19083390 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12865483 — Surrogate Endpoint (SUR): Blood pressure
Study 30786754 — Surrogate Endpoint (SUR): Blood pressure
Study 29856004 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 15714423 — Surrogate Endpoint (SUR): Blood pressure
Study 9484756 — Safety Biomarker (SAF): Reactive oxygen species
Study 7648765 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 2541637 — Surrogate Endpoint (SUR): Blood pressure
Study 25956401 — Surrogate Endpoint (SUR): Blood pressure
Study 25956401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25956401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25956401 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15351795 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11018853 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20388647 — Surrogate Endpoint (SUR): Serum potassium
Study 12714091 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12714091 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25900347 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24169061 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 21507143 — Monitoring Biomarker (MOI): Procalcitonin
Study 17297625 — Surrogate Endpoint (SUR): Blood pressure
Study 11484097 — Surrogate Endpoint (SUR): Bone mineral density
Study 9495424 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28678853 — Surrogate Endpoint (SUR): Bone mineral density
Study 19383112 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16704575 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 30110579 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30110579 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 26671747 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 26671747 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 26671747 — Predictive Biomarker (PRD): Microsatellite instability
Study 21349483 — Surrogate Endpoint (SUR): Serum creatinine
Study 2667745 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31282592 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9244228 — Surrogate Endpoint (SUR): Blood pressure
Study 16797280 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 10701823 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24139558 — Surrogate Endpoint (SUR): Blood pressure
Study 22337227 — Surrogate Endpoint (SUR): Bone mineral density
Study 18580613 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15955616 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 31704188 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17666194 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17666194 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 11084548 — Surrogate Endpoint (SUR): Blood pressure
Study 9487348 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8368227 — Surrogate Endpoint (SUR): Serum calcium
Study 31732742 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23969513 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19891902 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17805238 — Surrogate Endpoint (SUR): Serum calcium
Study 9734613 — Surrogate Endpoint (SUR): Blood pressure
Study 28263203 — Surrogate Endpoint (SUR): Blood pressure
Study 23844093 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 23844093 — Surrogate Endpoint (SUR): Blood pressure