TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9179367 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12759295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12759295 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9256623 — Surrogate Endpoint (SUR): Blood pressure
Study 3102372 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3102372 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 3102372 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1875206 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 19641457 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17136042 — Surrogate Endpoint (SUR): Blood pressure
Study 11842353 — Surrogate Endpoint (SUR): Bone mineral density
Study 7706804 — Surrogate Endpoint (SUR): Serum creatinine
Study 31453944 — Surrogate Endpoint (SUR): Blood pressure
Study 27876342 — Surrogate Endpoint (SUR): Blood pressure
Study 21438784 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21438784 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31888670 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 31888670 — Predictive Biomarker (PRD): SHOX2 mRNA
Genes: SHOX2; OG12X; SHOT
Study 31888670 — Predictive Biomarker (PRD): PTGER4 mRNA
Genes: PTGER4; PTGER2
Study 24674663 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22451195 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19035721 — Surrogate Endpoint (SUR): Blood pressure
Study 16332430 — Predictive Biomarker (PRD): PIR mRNA
Genes: PIR
Study 7578166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7578166 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18060342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18060342 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 18060342 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 18060342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8808540 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 2188826 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2188826 — Surrogate Endpoint (SUR): Blood pressure
Study 25907488 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23868621 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 11090571 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11090571 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26394780 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26394780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1448777 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1448777 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30629183 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 30629183 — Predictive Biomarker (PRD): MYF6 mRNA
Genes: MYF6; BHLHC4; MRF4
Study 30629183 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 28388981 — Surrogate Endpoint (SUR): Bone mineral density
Study 23170936 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 23170936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23170936 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23170936 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 23170936 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23170936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16391986 — Safety Biomarker (SAF): Reactive oxygen species
Study 16391986 — Surrogate Endpoint (SUR): Serum creatinine
Study 7700064 — Surrogate Endpoint (SUR): Blood pressure
Study 7700064 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28287486 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 25462393 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 25462393 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 19092692 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15718064 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 7890905 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3224534 — Surrogate Endpoint (SUR): Blood pressure
Study 27027616 — Safety Biomarker (SAF): Reactive oxygen species
Study 23400715 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23362148 — Surrogate Endpoint (SUR): Bone mineral density
Study 11380525 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7527229 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 7527229 — Surrogate Endpoint (SUR): Serum creatinine
Study 17076630 — Surrogate Endpoint (SUR): Blood pressure
Study 28545978 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 22443353 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 22443353 — Predictive Biomarker (PRD): ADIPOR2 mRNA
Genes: ADIPOR2; PAQR2
Study 11849660 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30855449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26368280 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15365213 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29117990 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25274978 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 24423823 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24423823 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 24423823 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 24423823 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 24423823 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study 18849230 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11042989 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29857773 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 27596557 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24115082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15807218 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9355019 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 9355019 — Surrogate Endpoint (SUR): Blood pressure
Study 7755476 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7755476 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 7755476 — Surrogate Endpoint (SUR): Blood pressure
Study 7755476 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12719046 — Surrogate Endpoint (SUR): Blood pressure
Study 31278329 — Predictive Biomarker (PRD): PLA2G2A mRNA
Genes: PLA2G2A; PLA2B; PLA2L; RASF-A
Study 31278329 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31278329 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31278329 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 31278329 — Predictive Biomarker (PRD): CASP3 mRNA
Genes: CASP3; CPP32
Study 19095597 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19095597 — Surrogate Endpoint (SUR): Blood pressure
Study 15751766 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9797112 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28854534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28854534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22089463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14630265 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16989935 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10392323 — Surrogate Endpoint (SUR): Blood pressure
Study 21791146 — Safety Biomarker (SAF): MTHFR
Study 2811958 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2811958 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22795453 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 16218799 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16218799 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2288819 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2288819 — Surrogate Endpoint (SUR): Blood pressure
Study 31487365 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23975654 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23975654 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19215678 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19215678 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29724350 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25023791 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 11952885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11952885 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11952885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24517053 — Surrogate Endpoint (SUR): Serum creatinine
Study 21768630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21768630 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21768630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16918596 — Safety Biomarker (SAF): Hyaluronic acid
Study 14728633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9760805 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9760805 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 7836524 — Safety Biomarker (SAF): Reactive oxygen species
Study 16557039 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 22649517 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 18234424 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18234424 — Predictive Biomarker (PRD): Hormone receptor
Study 26507452 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 16729287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16729287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11207873 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7963418 — Surrogate Endpoint (SUR): Bone mineral density
Study 2807362 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31419313 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 31419313 — Surrogate Endpoint (SUR): Bone mineral density
Study 15685543 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3902475 — Surrogate Endpoint (SUR): Serum potassium
Study 3902475 — Surrogate Endpoint (SUR): Blood pressure
Study 30067140 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2953870 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2953870 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 2953870 — Surrogate Endpoint (SUR): Serum testosterone
Study 25908281 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19345060 — Predictive Biomarker (PRD): HCST mRNA
Genes: HCST; DAP10; KAP10; PIK3AP; UNQ587/PRO1157
Study 15534123 — Surrogate Endpoint (SUR): Blood pressure
Study 15534123 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7634289 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17020434 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8142338 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8142338 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21270510 — Surrogate Endpoint (SUR): Blood pressure
Study 19371313 — Surrogate Endpoint (SUR): Blood pressure
Study 1365014 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 4048477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 29514234 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19180895 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15318852 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11262535 — Surrogate Endpoint (SUR): Blood pressure
Study 18769351 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15956111 — Surrogate Endpoint (SUR): Blood pressure
Study 2904313 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 23788305 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23788305 — Surrogate Endpoint (SUR): Blood pressure
Study 9037361 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29193478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29193478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11886010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9987087 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7027893 — Surrogate Endpoint (SUR): Blood pressure
Study 7027893 — Surrogate Endpoint (SUR): Serum potassium
Study 7027893 — Surrogate Endpoint (SUR): Serum uric acid
Study 27853891 — Safety Biomarker (SAF): Reactive oxygen species
Study 7962398 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7962398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31411950 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29042177 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 27827949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29458278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29458278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26984932 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24998572 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 20672296 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14767021 — Surrogate Endpoint (SUR): Blood pressure
Study 11518836 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11518836 — Surrogate Endpoint (SUR): Blood pressure
Study 9890718 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8032546 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8032546 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 11841454 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9749148 — Surrogate Endpoint (SUR): Blood pressure
Study 29074098 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29074098 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 29074098 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 25212278 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 24284608 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 15110921 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 11128916 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 2939218 — Surrogate Endpoint (SUR): Blood pressure
Study 22246011 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 30700591 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24034569 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21964893 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21964893 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 21964893 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24660585 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 24660585 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 24660585 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24660585 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 24660585 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 24660585 — Surrogate Endpoint (SUR): Serum creatinine
Study 21677432 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 24447501 — Surrogate Endpoint (SUR): Serum creatinine
Study 11547841 — Surrogate Endpoint (SUR): Bone mineral density
Study 19222416 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 10425052 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31134488 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31134488 — Predictive Biomarker (PRD): Hormone receptor
Study 23375819 — Surrogate Endpoint (SUR): Serum creatinine
Study 21516030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21516030 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22048237 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 22048237 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 18396374 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 12629088 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 12629088 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10597132 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8743100 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1836986 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1836986 — Surrogate Endpoint (SUR): Blood pressure
Study 14675055 — Surrogate Endpoint (SUR): Blood pressure
Study 8970145 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 3912093 — Surrogate Endpoint (SUR): Blood pressure
Study 26955702 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 23743017 — Surrogate Endpoint (SUR): Blood pressure
Study 16982276 — Safety Biomarker (SAF): Reactive oxygen species
Study 12488233 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3158125 — Surrogate Endpoint (SUR): Blood pressure
Study 20571129 — Surrogate Endpoint (SUR): Bone mineral density
Study 16336425 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 6448552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21220024 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15324535 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 15324535 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15324535 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 8373842 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8373842 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31856838 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 31856838 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 23628378 — Safety Biomarker (SAF): Hyaluronic acid
Study 17129610 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 14706014 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 30786937 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 27256812 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 27256812 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 27256812 — Predictive Biomarker (PRD): SLC47A2 mRNA
Genes: SLC47A2; MATE2
Study 27256812 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 27256812 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 27256812 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 14612001 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 14612001 — Surrogate Endpoint (SUR): Serum creatinine
Study 2158794 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2158794 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein