TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31774957 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31775714 — Surrogate Endpoint (SUR): Blood pressure
Study 31776899 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 31777783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31778074 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 31778074 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31778074 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 31778267 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31778798 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 31780237 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 31781957 — Surrogate Endpoint (SUR): Blood pressure
Study 31782492 — Surrogate Endpoint (SUR): Blood pressure
Study 31783178 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 31784451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31785185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31786971 — Surrogate Endpoint (SUR): Blood pressure
Study 31789931 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31790472 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 31790472 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 31790472 — Predictive Biomarker (PRD): STAT2 mRNA
Genes: STAT2
Study 31790472 — Predictive Biomarker (PRD): IRF1 mRNA
Genes: IRF1
Study 31790472 — Predictive Biomarker (PRD): IRF7 mRNA
Genes: IRF7
Study 31790472 — Safety Biomarker (SAF): Protein disulfide-isomerase A4
Genes: PDIA4; ERP70; ERP72
Study 31790472 — Predictive Biomarker (PRD): FAM72C mRNA
Genes: FAM72C
Study 31790472 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 31790472 — Predictive Biomarker (PRD): DHX58 mRNA
Genes: DHX58; D11LGP2E; LGP2
Study 31797105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31798754 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 31799498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31801624 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 31801624 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 31804102 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 31805424 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31806360 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 31806613 — Surrogate Endpoint (SUR): Blood pressure
Study 31806722 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31807036 — Monitoring Biomarker (MOI): HBV DNA
Study 31807567 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 31809241 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31809243 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31809725 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 31811682 — Predictive Biomarker (PRD): TFEB mRNA
Genes: TFEB; BHLHE35
Study 31811682 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study 31811953 — Safety Biomarker (SAF): Type I cytoskeletal 18 Keratin
Genes: KRT18; CYK18; PIG46
Study 31813938 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 31815579 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 31815739 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31815739 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 31816924 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 31817795 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 31817795 — Predictive Biomarker (PRD): FCGR3A
Genes: CD16; CD16a; FcgammaRIIIa; FcGRIIIA
Study 31819193 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 31819404 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31819632 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 31820157 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31820199 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31820981 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 31821339 — Surrogate Endpoint (SUR): Blood pressure
Study 31824147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31824147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31824943 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31825714 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31826340 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 31827323 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 31827323 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31828307 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 31831151 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 31831560 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 31833973 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 31834365 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31834916 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31835495 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 31835495 — Predictive Biomarker (PRD): Hormone receptor
Study 31836927 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 31837149 — Predictive Biomarker (PRD): RARS1 mRNA
Genes: RARS1; RARS
Study 31838007 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 31838007 — Predictive Biomarker (PRD): NTRK2 mRNA
Genes: NTRK2; TRKB
Study 31838007 — Predictive Biomarker (PRD): NTRK3 mRNA
Genes: NTRK3; TRKC
Study 31838015 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 31838512 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31838939 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 31839959 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 31839959 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31839959 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31840425 — Surrogate Endpoint (SUR): Blood pressure
Study 31840425 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31841594 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 31841594 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study 31842931 — Surrogate Endpoint (SUR): Serum potassium
Study 31842963 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 31843273 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study 31845423 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 31849164 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31849164 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31849202 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31849202 — Predictive Biomarker (PRD): Hormone receptor
Study 31849542 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 31851518 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31851732 — Predictive Biomarker (PRD): ZDHHC2 mRNA
Genes: ZDHHC2; REAM; REC; ZNF372
Study 31852810 — Predictive Biomarker (PRD): ARSA mRNA
Genes: ARSA
Study 31852810 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 31852810 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 31852810 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 31852810 — Predictive Biomarker (PRD): MYBPC3 mRNA
Genes: MYBPC3
Study 31852810 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study 31852810 — Predictive Biomarker (PRD): HSD17B4 mRNA
Genes: HSD17B4; EDH17B4; SDR8C1
Study 31852810 — Predictive Biomarker (PRD): PRODH mRNA
Genes: PRODH; PIG6; POX2; PRODH2
Study 31852847 — Predictive Biomarker (PRD): KLF15 mRNA
Genes: KLF15; KKLF
Study 31852847 — Predictive Biomarker (PRD): MEF2C mRNA
Genes: MEF2C
Study 31852847 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31853265 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31855231 — Monitoring Biomarker (MOI): Cell-free DNA
Study 31855577 — Predictive Biomarker (PRD): USO1 mRNA
Genes: USO1; VDP
Study 31856860 — Predictive Biomarker (PRD): CEBPB mRNA
Genes: CEBPB; TCF5; PP9092
Study 31858293 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study 31858327 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31858403 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 31860140 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 31862084 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 31862084 — Predictive Biomarker (PRD): SULT1A3 mRNA
Genes: SULT1A3; STM
Study 31863283 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31863305 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31865391 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31865391 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31865771 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31865797 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31866281 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 31867125 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31867125 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 31867125 — Surrogate Endpoint (SUR): Blood pressure
Study 31867437 — Surrogate Endpoint (SUR): Blood pressure
Study 31869417 — Predictive Biomarker (PRD): KIR2DL3 mRNA
Genes: KIR2DL3; CD158B2; KIRCL23; NKAT2
Study 31869417 — Predictive Biomarker (PRD): KIR3DL1 mRNA
Genes: KIR3DL1; CD158E; NKAT3; NKB1
Study 31870883 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31874111 — Predictive Biomarker (PRD): LRBA mRNA
Genes: LRBA; BGL; CDC4L; LBA
Study 31874111 — Predictive Biomarker (PRD): IKBKG mRNA
Genes: IKBKG; FIP3; NEMO
Study 31874111 — Predictive Biomarker (PRD): SAMD9L mRNA
Genes: SAMD9L; C7orf6; DRIF2; KIAA2005; UEF
Study 31874111 — Predictive Biomarker (PRD): SAMHD1 mRNA
Genes: SAMHD1; MOP5
Study 31874111 — Predictive Biomarker (PRD): TREX1 mRNA
Genes: TREX1
Study 31875915 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 31875915 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31875931 — Surrogate Endpoint (SUR): Serum uric acid
Study 31876124 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 31876911 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 31876927 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 31879782 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31879814 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 31880950 — Surrogate Endpoint (SUR): Hematologic response
Study 31881853 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 31881853 — Predictive Biomarker (PRD): KIAA1549 mRNA
Genes: KIAA1549
Study 31882281 — Surrogate Endpoint (SUR): Pathological complete response
Study 31882377 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 31882377 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 31885349 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31885750 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 31885750 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 31885750 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31885895 — Predictive Biomarker (PRD): TRO mRNA
Genes: TRO; KIAA1114; MAGED3
Study 31886028 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31887431 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31888507 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 31888507 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 31888643 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 31888672 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31888672 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31888703 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 31889230 — Surrogate Endpoint (SUR): Serum uric acid
Study 31890041 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31890043 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 31890996 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31891447 — Surrogate Endpoint (SUR): Blood pressure
Study 31891878 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 31894377 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31894377 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31895148 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31895696 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 31896448 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31896448 — Safety Biomarker (SAF): BDNF
Study 31896519 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 31896540 — Surrogate Endpoint (SUR): Serum creatinine
Study 31898110 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 31898493 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31898757 — Surrogate Endpoint (SUR): Blood pressure
Study 31900186 — Predictive Biomarker (PRD): APCS mRNA
Genes: APCS; PTX2
Study 31903182 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31905377 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31907067 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31907538 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31907538 — Surrogate Endpoint (SUR): Bone mineral density
Study 31907828 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31907828 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31908441 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31908813 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 31909303 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31911180 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 31911180 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31911180 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 31912462 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 31912462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31912874 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 31912874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31912905 — Predictive Biomarker (PRD): STK26 mRNA
Genes: STK26; MASK; MST4
Study 31912905 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31912905 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 31912905 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 31912905 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31912905 — Predictive Biomarker (PRD): PAK1 mRNA
Genes: PAK1
Study 31912905 — Predictive Biomarker (PRD): LATS1 mRNA
Genes: LATS1; WARTS
Study 31912905 — Predictive Biomarker (PRD): MAP4K4 mRNA
Genes: MAP4K4; HGK; KIAA0687; NIK
Study 31912905 — Predictive Biomarker (PRD): RAP2A mRNA
Genes: RAP2A
Study 31915028 — Predictive Biomarker (PRD): HIPK2 mRNA
Genes: HIPK2
Study 31915028 — Safety Biomarker (SAF): HIPK2
Study 31915195 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 31915195 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31915195 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31918324 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31918324 — Predictive Biomarker (PRD): Hormone receptor
Study 31919404 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 31920324 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 31921371 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31921371 — Safety Biomarker (SAF): BDNF
Study 31923435 — Surrogate Endpoint (SUR): Blood pressure
Study 31923800 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31924241 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 31924241 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31924461 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31928530 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31928530 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 31928530 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 31930302 — Surrogate Endpoint (SUR): Blood pressure
Study 31930374 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 31930513 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 31931024 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31931024 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study 31931024 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31931024 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 31931024 — Predictive Biomarker (PRD): STEAP1 mRNA
Genes: STEAP1; PRSS24; STEAP
Study 31931024 — Predictive Biomarker (PRD): SOX2 mRNA
Genes: SOX2
Study 31931767 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 31932137 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31932137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31932137 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31932137 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31932246 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31934829 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31935746 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 31937118 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31937266 — Surrogate Endpoint (SUR): Blood pressure
Study 31937310 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 31937616 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31939531 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 31940346 — Surrogate Endpoint (SUR): Blood pressure
Study 31942430 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31943691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31948451 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31948451 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 31949011 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31949011 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31951027 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 31951027 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 31951027 — Predictive Biomarker (PRD): ULK1 mRNA
Genes: ULK1; KIAA0722
Study 31951027 — Predictive Biomarker (PRD): ATG13 mRNA
Genes: ATG13; KIAA0652
Study 31951027 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 31952501 — Surrogate Endpoint (SUR): Blood pressure
Study 31952983 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 31953313 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31954624 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31956961 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 31958096 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31958096 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 31959034 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31959169 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31959735 — Predictive Biomarker (PRD): DNAH10 mRNA
Genes: DNAH10; KIAA2017
Study 31959992 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 31960953 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31961766 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31961822 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 31961829 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 31963294 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 31964784 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31969132 — Safety Biomarker (SAF): BDNF