TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16982228 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16982228 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 16982228 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 16982228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15208650 — Surrogate Endpoint (SUR): Serum calcium
Study 15208650 — Surrogate Endpoint (SUR): Blood pressure
Study 1696671 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1696671 — Surrogate Endpoint (SUR): Blood pressure
Study 21248295 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17588810 — Predictive Biomarker (PRD): PTMS mRNA
Genes: PTMS
Study 15572757 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30740133 — Surrogate Endpoint (SUR): Blood pressure
Study 30740133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28431800 — Predictive Biomarker (PRD): PTPRD mRNA
Genes: PTPRD
Study 28431800 — Predictive Biomarker (PRD): LRRC4C mRNA
Genes: LRRC4C; KIAA1580; NGL1; UNQ292/PRO331
Study 28431800 — Predictive Biomarker (PRD): NRXN1 mRNA
Genes: NRXN1
Study 28431800 — Predictive Biomarker (PRD): SLITRK1 mRNA
Genes: SLITRK1; KIAA1910; LRRC12; UNQ233/PRO266
Study 28431800 — Predictive Biomarker (PRD): MAGI1 mRNA
Genes: MAGI1; AIP3; BAIAP1; BAP1; TNRC19
Study 28431800 — Predictive Biomarker (PRD): MAGI2 mRNA
Genes: MAGI2; ACVRINP1; AIP1; KIAA0705
Study 28431800 — Predictive Biomarker (PRD): NBEA mRNA
Genes: NBEA; BCL8B; KIAA1544; LYST2
Study 28431800 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 28431800 — Predictive Biomarker (PRD): KALRN mRNA
Genes: KALRN; DUET; DUO; HAPIP; TRAD
Study 28431800 — Predictive Biomarker (PRD): RBFOX1 mRNA
Genes: RBFOX1; A2BP; A2BP1; FOX1; HRNBP1
Study 28431800 — Predictive Biomarker (PRD): KCNAB1 mRNA
Genes: KCNAB1; KCNA1B
Study 22798383 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 22798383 — Predictive Biomarker (PRD): TET1 mRNA
Genes: TET1; CXXC6; KIAA1676; LCX
Study 21125811 — Surrogate Endpoint (SUR): Blood pressure
Study 21125811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23838844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23838844 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16545434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8164940 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31295916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26009024 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21298654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21298654 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21298654 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19026531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16883221 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16883221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16883221 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16883221 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16883221 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9010482 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 9010482 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 9010482 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 30528419 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30528419 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27684085 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9052309 — Surrogate Endpoint (SUR): Blood pressure
Study 30214183 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23909452 — Surrogate Endpoint (SUR): Blood pressure
Study 23909452 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23909452 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23909452 — Surrogate Endpoint (SUR): Serum testosterone
Study 21168874 — Surrogate Endpoint (SUR): Serum testosterone
Study 17079759 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27002500 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18479773 — Monitoring Biomarker (MOI): HBV DNA
Study 16641918 — Surrogate Endpoint (SUR): Serum creatinine
Study 12737020 — Surrogate Endpoint (SUR): Serum calcium
Study 12737020 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 23535358 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15282657 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 9285658 — Surrogate Endpoint (SUR): Blood pressure
Study 29508904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20036362 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 24369828 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24369828 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16170078 — Safety Biomarker (SAF): Interleukin 1
Study 16170078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3068597 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11461095 — Surrogate Endpoint (SUR): Blood pressure
Study 3327846 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9549737 — Surrogate Endpoint (SUR): Blood pressure
Study 7860471 — Surrogate Endpoint (SUR): Blood pressure
Study 26596627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6240405 — Surrogate Endpoint (SUR): Blood pressure
Study 20462428 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 7492487 — Surrogate Endpoint (SUR): Serum creatinine
Study 31101323 — Surrogate Endpoint (SUR): Blood pressure
Study 28588686 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18162932 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26995281 — Surrogate Endpoint (SUR): Blood pressure
Study 10639654 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 15681523 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31694684 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 19833260 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 19833260 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19833260 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 19833260 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24247300 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 10972608 — Surrogate Endpoint (SUR): Blood pressure
Study 8725722 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 22219405 — Surrogate Endpoint (SUR): Blood pressure
Study 24906857 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19296044 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 19296044 — Surrogate Endpoint (SUR): Bone mineral density
Study 11575527 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26939320 — Surrogate Endpoint (SUR): Serum creatinine
Study 16859530 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 26669226 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26669226 — Surrogate Endpoint (SUR): Blood pressure
Study 1417537 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 1417537 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 27348249 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24824118 — Monitoring Biomarker (MOI): HBV DNA
Study 20188583 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15926717 — Predictive Biomarker (PRD): CA4 mRNA
Genes: CA4
Study 9699932 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7877158 — Surrogate Endpoint (SUR): Blood pressure
Study 3266005 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28818054 — Surrogate Endpoint (SUR): Serum creatinine
Study 21384334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16616012 — Surrogate Endpoint (SUR): Blood pressure
Study 30735532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30805363 — Predictive Biomarker (PRD): PRF1 mRNA
Genes: PRF1; PFP
Study 26053030 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24653917 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 9029748 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 30461315 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 25825393 — Safety Biomarker (SAF): Hyaluronic acid
Study 23649189 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21411446 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 14981107 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 811982 — Surrogate Endpoint (SUR): Blood pressure
Study 30896608 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24944260 — Surrogate Endpoint (SUR): Blood pressure
Study 15379738 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20024753 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17058023 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14567822 — Surrogate Endpoint (SUR): Blood pressure
Study 6794420 — Surrogate Endpoint (SUR): Blood pressure
Study 26401704 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21152932 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 23573836 — Predictive Biomarker (PRD): SPRR3 mRNA
Genes: SPRR3; SPRC
Study 21740240 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 21740240 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 30630559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30630559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28667118 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21739686 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 8482557 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 8482557 — Surrogate Endpoint (SUR): Pathological complete response
Study 28882161 — Predictive Biomarker (PRD): EEF1A2 mRNA
Genes: EEF1A2; EEF1AL; STN
Study 26333545 — Surrogate Endpoint (SUR): Blood pressure
Study 19080431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2659003 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30325764 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19419254 — Surrogate Endpoint (SUR): Blood pressure
Study 17907081 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15198380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9554677 — Surrogate Endpoint (SUR): Blood pressure
Study 20467943 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10404769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1535580 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1535580 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 17989110 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16301267 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 16928616 — Predictive Biomarker (PRD): GAPDH mRNA
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 27917793 — Surrogate Endpoint (SUR): Serum sodium
Study 19958442 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 19958442 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15756156 — Surrogate Endpoint (SUR): Blood pressure
Study 12479634 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31816191 — Surrogate Endpoint (SUR): Blood pressure
Study 26071656 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23953030 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 23953030 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 23953030 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 18344568 — Predictive Biomarker (PRD): FIP1L1 mRNA
Genes: FIP1L1; FIP1; RHE
Study 18344568 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 18344568 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 7960021 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26519345 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23686706 — Surrogate Endpoint (SUR): Serum testosterone
Study 3046824 — Surrogate Endpoint (SUR): Blood pressure
Study 26705299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25636071 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 23690420 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16884341 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16884341 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 11073858 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 22466349 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 31711059 — Surrogate Endpoint (SUR): Serum uric acid
Study 22363556 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22363556 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22363556 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22363556 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24602579 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 17398191 — Surrogate Endpoint (SUR): Blood pressure
Study 10451039 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10451039 — Surrogate Endpoint (SUR): Blood pressure
Study 28652463 — Surrogate Endpoint (SUR): Blood pressure
Study 28652463 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23081732 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 23081732 — Surrogate Endpoint (SUR): Bone mineral density
Study 9159629 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8205297 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8205297 — Surrogate Endpoint (SUR): Blood pressure
Study 3581681 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27601237 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24709304 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 25850440 — Surrogate Endpoint (SUR): Blood pressure
Study 22647618 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 31928229 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23949801 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16142502 — Surrogate Endpoint (SUR): Bone mineral density
Study 14727367 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 11527612 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8420344 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8420344 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31230147 — Safety Biomarker (SAF): Bacteroides intestinalis
Study 16618270 — Surrogate Endpoint (SUR): Blood pressure
Study 10707514 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28070639 — Surrogate Endpoint (SUR): Blood pressure
Study 30645840 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 20501774 — Surrogate Endpoint (SUR): Bone mineral density
Study 30448598 — Monitoring Biomarker (MOI): HBV DNA
Study 30448598 — Surrogate Endpoint (SUR): Bone mineral density
Study 21863389 — Surrogate Endpoint (SUR): Serum potassium
Study 21863389 — Surrogate Endpoint (SUR): Blood pressure
Study 16538011 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18239197 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 7224205 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31567872 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 31567872 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 27839807 — Surrogate Endpoint (SUR): Serum creatinine
Study 21416238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15028129 — Surrogate Endpoint (SUR): Blood pressure
Study 28325823 — Surrogate Endpoint (SUR): Blood pressure
Study 10971099 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8877910 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 6378450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29239764 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25341118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14644697 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6397454 — Surrogate Endpoint (SUR): Blood pressure
Study 23018304 — Safety Biomarker (SAF): Hyaluronic acid
Study 15542577 — Surrogate Endpoint (SUR): Blood pressure
Study 6326562 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6326562 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6326562 — Surrogate Endpoint (SUR): Serum calcium
Study 30647402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30647402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12466782 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7844610 — Surrogate Endpoint (SUR): Serum creatinine
Study 29117276 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8040900 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31461123 — Surrogate Endpoint (SUR): Blood pressure
Study 28396303 — Surrogate Endpoint (SUR): Blood pressure
Study 26134386 — Surrogate Endpoint (SUR): Bone mineral density
Study 9766255 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3041874 — Surrogate Endpoint (SUR): Blood pressure
Study 3041874 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 12820059 — Safety Biomarker (SAF): Th2 cell
Study 29074041 — Surrogate Endpoint (SUR): Blood pressure
Study 21401729 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18544983 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21546099 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 21546099 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18308653 — Surrogate Endpoint (SUR): Bone mineral density
Study 8821108 — Surrogate Endpoint (SUR): Bacterial count
Study 1951474 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1951474 — Surrogate Endpoint (SUR): Blood pressure
Study 6119096 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17183623 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 21300933 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 3752464 — Surrogate Endpoint (SUR): Blood pressure
Study 31043093 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 9122553 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 27523719 — Surrogate Endpoint (SUR): Blood pressure
Study 24158227 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 22999073 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22999073 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 10540091 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30448193 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 30448193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22546988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22546988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19616668 — Surrogate Endpoint (SUR): Blood pressure
Study 8200552 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 20978528 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20978528 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18718556 — Surrogate Endpoint (SUR): Serum creatinine
Study 12965979 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12965979 — Surrogate Endpoint (SUR): Blood pressure
Study 12965979 — Surrogate Endpoint (SUR): Serum creatinine
Study 23914920 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23914920 — Surrogate Endpoint (SUR): Blood pressure
Study 21859656 — Surrogate Endpoint (SUR): Blood pressure
Study 18257271 — Surrogate Endpoint (SUR): Bone mineral density