TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30480489 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 30480549 — Predictive Biomarker (PRD): SUMO3 mRNA
Genes: SUMO3; SMT3A; SMT3H1
Study 30480549 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30484084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30484934 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 30486767 — Monitoring Biomarker (MOI): Cell-free DNA
Study 30486767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30487142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30487982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30487998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30488420 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 30496606 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study 30497198 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study 30497198 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30498576 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 30498824 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 30499198 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 30501490 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30501869 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 30501869 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 30501869 — Surrogate Endpoint (SUR): Serum creatinine
Study 30501916 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30501916 — Surrogate Endpoint (SUR): Blood pressure
Study 30503187 — Surrogate Endpoint (SUR): Serum creatinine
Study 30503909 — Surrogate Endpoint (SUR): Blood pressure
Study 30506110 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30506309 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30507862 — Surrogate Endpoint (SUR): Blood pressure
Study 30509296 — Monitoring Biomarker (MOI): Cell-free DNA
Study 30510361 — Predictive Biomarker (PRD): GDA mRNA
Genes: GDA; KIAA1258
Study 30510439 — Surrogate Endpoint (SUR): Blood pressure
Study 30512189 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30514390 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30515367 — Predictive Biomarker (PRD): Hormone receptor
Study 30515367 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30515430 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 30515430 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 30517727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30517727 — Surrogate Endpoint (SUR): Blood pressure
Study 30518502 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30518502 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 30520689 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 30522700 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30522992 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 30524702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30527203 — Monitoring Biomarker (MOI): Procalcitonin
Study 30527203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30527203 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30529085 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30529597 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30529597 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30532779 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 30534152 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 30536725 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30536725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30536725 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 30536725 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30536810 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 30536810 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 30536810 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 30536810 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 30537010 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 30537010 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 30537877 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30538102 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30539492 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30539492 — Predictive Biomarker (PRD): Hormone receptor
Study 30540645 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 30540645 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30541456 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 30541505 — Monitoring Biomarker (MOI): Procalcitonin
Study 30541571 — Surrogate Endpoint (SUR): Blood pressure
Study 30542289 — Surrogate Endpoint (SUR): Blood pressure
Study 30542322 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 30542377 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30543050 — Predictive Biomarker (PRD): LGALSL mRNA
Genes: LGALSL; GRP; HSPC159
Study 30543347 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30543347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30543347 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30544060 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 30544235 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 30545672 — Surrogate Endpoint (SUR): Serum uric acid
Study 30546948 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 30546962 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study 30547830 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 30548438 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 30549425 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30554141 — Predictive Biomarker (PRD): MAP3K7 mRNA
Genes: MAP3K7; TAK1
Study 30555051 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30556332 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 30557448 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 30557521 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30557521 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 30558987 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30558987 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 30559420 — Predictive Biomarker (PRD): CEP290 mRNA
Genes: CEP290; BBS14; KIAA0373; NPHP6
Study 30561367 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 30561367 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 30561563 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30562390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30562390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30562587 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 30562587 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 30563576 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30563818 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 30564373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30564451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30565371 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30566616 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 30567529 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30567584 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 30568035 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 30568035 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 30570526 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30570649 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30570744 — Predictive Biomarker (PRD): CREBBP mRNA
Genes: CREBBP; CBP
Study 30570744 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30570763 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30571184 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30571184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30571191 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30571191 — Surrogate Endpoint (SUR): Blood pressure
Study 30571194 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 30571194 — Predictive Biomarker (PRD): ESS2 mRNA
Genes: ESS2; DGCR13; DGCR14; DGSH; DGSI; ES2
Study 30571553 — Surrogate Endpoint (SUR): Blood pressure
Study 30572891 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 30572922 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 30573492 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 30573564 — Predictive Biomarker (PRD): APOBEC3G mRNA
Genes: APOBEC3G; MDS019
Study 30574343 — Surrogate Endpoint (SUR): Blood pressure
Study 30574672 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 30574672 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 30574672 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30574672 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 30574833 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 30575311 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 30575311 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 30576085 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 30576085 — Surrogate Endpoint (SUR): Bone mineral density
Study 30576085 — Monitoring Biomarker (MOI): HBV DNA
Study 30576085 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30576970 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 30577768 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 30577883 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 30577988 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30577988 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30579270 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 30580128 — Surrogate Endpoint (SUR): Serum uric acid
Study 30580128 — Surrogate Endpoint (SUR): Blood pressure
Study 30580852 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 30581606 — Surrogate Endpoint (SUR): Blood pressure
Study 30581893 — Surrogate Endpoint (SUR): Serum calcium
Study 30581893 — Surrogate Endpoint (SUR): Bone mineral density
Study 30583934 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 30583995 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 30584317 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30585255 — Predictive Biomarker (PRD): MDM2
Genes: HDM2; MGC5370
Study 30585255 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 30585255 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30585255 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 30586731 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30586731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30586733 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30586745 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 30586745 — Surrogate Endpoint (SUR): Blood pressure
Study 30587228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30587418 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 30589495 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30589495 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30590505 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 30590564 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30590596 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30591548 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 30591548 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30593513 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30593513 — Predictive Biomarker (PRD): Hormone receptor
Study 30594245 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 30595681 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 30596880 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30597300 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30598343 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30598500 — Predictive Biomarker (PRD): PLK1 mRNA
Genes: PLK1; PLK
Study 30598833 — Surrogate Endpoint (SUR): Blood pressure
Study 30601986 — Surrogate Endpoint (SUR): Bone mineral density
Study 30603797 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30603797 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30603797 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 30605211 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 30606204 — Predictive Biomarker (PRD): HAS2 mRNA
Genes: HAS2
Study 30606204 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 30606204 — Predictive Biomarker (PRD): GREM1 mRNA
Genes: GREM1; CKTSF1B1; DAND2; DRM; PIG2
Study 30607629 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30607629 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 30607798 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 30611192 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30612558 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 30612568 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 30612602 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 30613413 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 30615047 — Surrogate Endpoint (SUR): Blood pressure
Study 30615302 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30617104 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30617563 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 30618179 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30619351 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 30619351 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 30619351 — Predictive Biomarker (PRD): ICOSLG mRNA
Genes: ICOSLG; B7H2; B7RP1; ICOSL; KIAA0653
Study 30619351 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study 30619351 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 30619351 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 30619502 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30621698 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30621982 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 30622321 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30622463 — Predictive Biomarker (PRD): SIGLEC1 mRNA
Genes: SIGLEC1; SN
Study 30622737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30624149 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 30624149 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 30624149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30624546 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 30624546 — Predictive Biomarker (PRD): NTRK2 mRNA
Genes: NTRK2; TRKB
Study 30624546 — Predictive Biomarker (PRD): NTRK3 mRNA
Genes: NTRK3; TRKC
Study 30624587 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 30624587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30624603 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30624603 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 30624987 — Surrogate Endpoint (SUR): Blood pressure
Study 30630632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30630956 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30631878 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30633573 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 30633573 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 30634942 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30634942 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30635024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30635165 — Predictive Biomarker (PRD): PARP3 mRNA
Genes: PARP3; ADPRT3; ADPRTL3
Study 30635165 — Predictive Biomarker (PRD): Microsatellite instability
Study 30636249 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 30636249 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 30637483 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30637570 — Surrogate Endpoint (SUR): Blood pressure
Study 30637784 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 30638856 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30638856 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 30638856 — Surrogate Endpoint (SUR): Serum creatinine
Study 30640706 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 30642372 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 30642372 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 30642372 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 30642372 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30642373 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 30642537 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30643455 — Predictive Biomarker (PRD): Hormone receptor
Study 30643455 — Surrogate Endpoint (SUR): Bone mineral density
Study 30644132 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 30644648 — Predictive Biomarker (PRD): SPATS2L mRNA
Genes: SPATS2L; DNAPTP6; SP1224
Study 30644648 — Predictive Biomarker (PRD): IL33 mRNA
Genes: IL33; C9orf26; IL1F11; NFHEV
Study 30646425 — Predictive Biomarker (PRD): PDE6B mRNA
Genes: PDE6B; PDEB
Study 30646942 — Predictive Biomarker (PRD): ERAP1 mRNA
Genes: ERAP1; APPILS; ARTS1; KIAA0525; UNQ584/PRO1154
Study 30646942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30647082 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 30648126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30648632 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30649177 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30649524 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 30654137 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 30657223 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor