TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28157261 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 28157261 — Predictive Biomarker (PRD): PTK6 mRNA
Genes: PTK6; BRK
Study 23129021 — Surrogate Endpoint (SUR): Blood pressure
Study 21273603 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 21273603 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 26161601 — Predictive Biomarker (PRD): CCHCR1 mRNA
Genes: CCHCR1; C6orf18; HCR
Study 20308972 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16291760 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28877748 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 28877748 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28877748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28877748 — Pharmacodynamic Biomarker (PDY): RAS peptides
Study 23602601 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17129383 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17129383 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17129383 — Predictive Biomarker (PRD): Hormone receptor
Study 11401123 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 6695162 — Surrogate Endpoint (SUR): Blood pressure
Study 30807294 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20190028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20190028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20190028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12753323 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29898870 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23660331 — Surrogate Endpoint (SUR): Blood pressure
Study 14510794 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 14510794 — Surrogate Endpoint (SUR): Blood pressure
Study 8630674 — Surrogate Endpoint (SUR): Blood pressure
Study 20855664 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20855664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2167330 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2167330 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25452452 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24095246 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 22303711 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 22303711 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 9408153 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 29444414 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29444414 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23225450 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 15277322 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9107160 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3147048 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27350068 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 26276751 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26276751 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 26276751 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22976766 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22976766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18346503 — Surrogate Endpoint (SUR): Blood pressure
Study 8876022 — Surrogate Endpoint (SUR): Blood pressure
Study 31809622 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 14762357 — Surrogate Endpoint (SUR): Blood pressure
Study 27312122 — Safety Biomarker (SAF): Reactive oxygen species
Study 21906549 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8747308 — Surrogate Endpoint (SUR): Blood pressure
Study 2117625 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 2117625 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2117625 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23402546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21559284 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 21559284 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 21559284 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17692784 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 17692784 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 17692784 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 21943153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19283744 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3427552 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 30371334 — Predictive Biomarker (PRD): MVK mRNA
Genes: MVK
Study 30371334 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 30371334 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30371334 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21279990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7510990 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3524231 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 10641576 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20189174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20189174 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20189174 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20189174 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20189174 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17379054 — Surrogate Endpoint (SUR): Blood pressure
Study 28232599 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16833023 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8375090 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 29283072 — Surrogate Endpoint (SUR): Blood pressure
Study 24930870 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 20445497 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20445497 — Surrogate Endpoint (SUR): Blood pressure
Study 20445497 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 29729978 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29729978 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27063162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16261287 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 3711599 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 21210776 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 11549539 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11549539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8299661 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 8299661 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 8299661 — Surrogate Endpoint (SUR): Blood pressure
Study 8308771 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30893450 — Predictive Biomarker (PRD): VSIR mRNA
Genes: VSIR; C10orf54; SISP1; VISTA; PP2135; UNQ730/PRO1412
Study 28619115 — Surrogate Endpoint (SUR): Blood pressure
Study 25553559 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25553559 — Surrogate Endpoint (SUR): Blood pressure
Study 8798245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26519693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23254732 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19064982 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 19064982 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 8813779 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27053264 — Surrogate Endpoint (SUR): Blood pressure
Study 19965822 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17324010 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 3109060 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29043496 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 10080585 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 8622038 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24786016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2096210 — Surrogate Endpoint (SUR): Blood pressure
Study 30510079 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 30510079 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25904685 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25904685 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 17045903 — Surrogate Endpoint (SUR): Blood pressure
Study 15613917 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15613917 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7690689 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3755561 — Surrogate Endpoint (SUR): Blood pressure
Study 15756212 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14620312 — Surrogate Endpoint (SUR): Blood pressure
Study 10500313 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10500313 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1825737 — Surrogate Endpoint (SUR): Serum testosterone
Study 16860259 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16860259 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 16860259 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16860259 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16860259 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11355946 — Predictive Biomarker (PRD): TERF1 mRNA
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study 21715517 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 16516598 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12374901 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9818697 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 19253793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19253793 — Safety Biomarker (SAF): IL-6 and IL-10
Study 7954998 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 7954998 — Surrogate Endpoint (SUR): Blood pressure
Study 17205818 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 17205818 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17205818 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 11094000 — Surrogate Endpoint (SUR): Blood pressure
Study 31464192 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 22464576 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22464576 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20044534 — Surrogate Endpoint (SUR): Blood pressure
Study 12356708 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 29268667 — Surrogate Endpoint (SUR): Blood pressure
Study 8930429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26564102 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 14608138 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1634926 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6202572 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 19833893 — Surrogate Endpoint (SUR): Blood pressure
Study 10321443 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10321443 — Surrogate Endpoint (SUR): Blood pressure
Study 9562690 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 7473480 — Predictive Biomarker (PRD): TP53INP1 mRNA
Genes: TP53INP1; P53DINP1; SIP
Study 21234672 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21234672 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10367612 — Surrogate Endpoint (SUR): Blood pressure
Study 31395096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26381519 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 19339794 — Surrogate Endpoint (SUR): Bone mineral density
Study 19339794 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 16931891 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 29572600 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 23855318 — Surrogate Endpoint (SUR): Blood pressure
Study 8904739 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27434297 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 27434297 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 20965978 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 20965978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20965978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29659183 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29659183 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29126422 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 18091548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18091548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19849857 — Surrogate Endpoint (SUR): Blood pressure
Study 14679399 — Predictive Biomarker (PRD): OAS2 mRNA
Genes: OAS2
Study 14679399 — Predictive Biomarker (PRD): EIF2AK2 mRNA
Genes: EIF2AK2; PKR; PRKR
Study 2069370 — Surrogate Endpoint (SUR): Serum creatinine
Study 31041545 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 28768217 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28768217 — Surrogate Endpoint (SUR): Pathological complete response
Study 16538000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16538000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16538000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23911013 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 11036119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27353245 — Surrogate Endpoint (SUR): Blood pressure
Study 24029478 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 21145618 — Safety Biomarker (SAF): Interleukin 12
Study 29546832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29546832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24782291 — Surrogate Endpoint (SUR): Blood pressure
Study 24782291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11793395 — Predictive Biomarker (PRD): HCG22 mRNA
Genes: HCG22; G2; PBMUCL2
Study 24692481 — Surrogate Endpoint (SUR): Blood pressure
Study 22745199 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 11989073 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7794578 — Surrogate Endpoint (SUR): Blood pressure
Study 27862339 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 16320346 — Surrogate Endpoint (SUR): Bone mineral density
Study 16320346 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16320346 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7989461 — Surrogate Endpoint (SUR): Bone mineral density
Study 27622692 — Surrogate Endpoint (SUR): Bone mineral density
Study 18760583 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21047602 — Safety Biomarker (SAF): Hyaluronic acid
Study 11856774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26151734 — Surrogate Endpoint (SUR): Blood pressure
Study 26151734 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26151734 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15087038 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12032111 — Surrogate Endpoint (SUR): Blood pressure
Study 23682110 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11726088 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 7910126 — Surrogate Endpoint (SUR): Blood pressure
Study 31916418 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 21778278 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16390757 — Surrogate Endpoint (SUR): Bone mineral density
Study 11466599 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9236433 — Surrogate Endpoint (SUR): Blood pressure
Study 8433880 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25082656 — Surrogate Endpoint (SUR): Serum uric acid
Study 10664923 — Surrogate Endpoint (SUR): Blood pressure
Study 22304620 — Predictive Biomarker (PRD): OGT mRNA
Genes: OGT
Study 18514323 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 12578787 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 31232940 — Surrogate Endpoint (SUR): Serum creatinine
Study 19229822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15149168 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 15149168 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 10024217 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 27393505 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 22808940 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 18263856 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25204509 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25204509 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 25204509 — Surrogate Endpoint (SUR): Blood pressure
Study 10917405 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31958417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 31958417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 31958417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 29891218 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 29891218 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 20217116 — Surrogate Endpoint (SUR): Bone mineral density
Study 18555934 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11571447 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11571447 — Surrogate Endpoint (SUR): Serum creatinine
Study 31462310 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31462310 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 30002931 — Surrogate Endpoint (SUR): Blood pressure
Study 19623780 — Safety Biomarker (SAF): Reactive oxygen species
Study 12142121 — Surrogate Endpoint (SUR): Blood pressure
Study 9741369 — Surrogate Endpoint (SUR): Blood pressure
Study 8041232 — Surrogate Endpoint (SUR): Blood pressure
Study 26188003 — Predictive Biomarker (PRD): WBP2NL mRNA
Genes: WBP2NL; PAWP
Study 21768458 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23548123 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23548123 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 23548123 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23548123 — Surrogate Endpoint (SUR): Serum creatinine
Study 23548123 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23548123 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21742106 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 16704693 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 27466718 — Safety Biomarker (SAF): Interleukin 1
Study 9768926 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31226405 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 28189481 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 28189481 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28189481 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16092048 — Surrogate Endpoint (SUR): Serum creatinine