TrialPanorama/TrialPanorama-database huggingface dataset:
Study 2345592 — Surrogate Endpoint (SUR): Blood pressure
Study 31520480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21299472 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19755916 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7240435 — Surrogate Endpoint (SUR): Blood pressure
Study 30019498 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27127 — Surrogate Endpoint (SUR): Blood pressure
Study 27127 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25514804 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25514804 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22038349 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9421852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9421852 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 26211516 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1727741 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1727741 — Surrogate Endpoint (SUR): Blood pressure
Study 19775041 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 17106320 — Surrogate Endpoint (SUR): Blood pressure
Study 8213583 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8213583 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2485066 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 2485066 — Surrogate Endpoint (SUR): Blood pressure
Study 28749571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27273854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16799778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22489519 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20146569 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 15918381 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 12875680 — Monitoring Biomarker (MOI): HBV DNA
Study 31332025 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 22080174 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20730486 — Surrogate Endpoint (SUR): Bone mineral density
Study 31702486 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31702486 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31702486 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 31702486 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 26237354 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23351309 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 23351309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21148235 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19258430 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 15650345 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7827373 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 7827373 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23953645 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23953645 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30909214 — Surrogate Endpoint (SUR): Blood pressure
Study 22564353 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22564353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22564353 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22564353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 402794 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 17822977 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17201456 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17201456 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 29127949 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29127949 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26091907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19020127 — Surrogate Endpoint (SUR): Blood pressure
Study 2245049 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23407222 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16625234 — Surrogate Endpoint (SUR): Blood pressure
Study 24722649 — Surrogate Endpoint (SUR): Blood pressure
Study 23006736 — Surrogate Endpoint (SUR): Blood pressure
Study 18388929 — Safety Biomarker (SAF): Fibroblast growth factor 1
Genes: FGF1
Study 12775947 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10727077 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 6091247 — Surrogate Endpoint (SUR): Blood pressure
Study 14999424 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7843761 — Surrogate Endpoint (SUR): Blood pressure
Study 31757 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31757 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27502846 — Surrogate Endpoint (SUR): Serum creatinine
Study 22326605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16723021 — Surrogate Endpoint (SUR): Blood pressure
Study 8746604 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 8746604 — Surrogate Endpoint (SUR): Blood pressure
Study 19719960 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19719960 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1924023 — Surrogate Endpoint (SUR): Blood pressure
Study 30785406 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 20531348 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18840821 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8961505 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6340275 — Surrogate Endpoint (SUR): Serum creatinine
Study 20402305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20402305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17556408 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1388702 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 29798502 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 29798502 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 27087103 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10547465 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8739854 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31596491 — Surrogate Endpoint (SUR): Blood pressure
Study 24637999 — Predictive Biomarker (PRD): CDCA7L mRNA
Genes: CDCA7L; HR1; JPO2; R1
Study 24637999 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 22289280 — Surrogate Endpoint (SUR): Bone mineral density
Study 24501378 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24501378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 24501378 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study 24501378 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19170197 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 9729573 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7802151 — Surrogate Endpoint (SUR): Blood pressure
Study 26419732 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 16754923 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23234763 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23234763 — Predictive Biomarker (PRD): Hormone receptor
Study 2200237 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1705137 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 28422001 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 23832170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1377036 — Surrogate Endpoint (SUR): Serum creatinine
Study 31375087 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29468764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29468764 — Surrogate Endpoint (SUR): Blood pressure
Study 29468764 — Safety Biomarker (SAF): Reactive oxygen species
Study 29468764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29468764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26731258 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26731258 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9408667 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study 9408667 — Predictive Biomarker (PRD): GNL3 mRNA
Genes: GNL3; E2IG3; NS
Study 29504794 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 6413114 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 6413114 — Predictive Biomarker (PRD): TIMM8A mRNA
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 15189367 — Surrogate Endpoint (SUR): Bone mineral density
Study 9797792 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2487544 — Surrogate Endpoint (SUR): Blood pressure
Study 21694613 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30136858 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30136858 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30136858 — Surrogate Endpoint (SUR): Blood pressure
Study 30136858 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24158631 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 27639190 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 25786106 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27170530 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27170530 — Surrogate Endpoint (SUR): Blood pressure
Study 27170530 — Surrogate Endpoint (SUR): Serum potassium
Study 27170530 — Surrogate Endpoint (SUR): Serum creatinine
Study 10072229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 207295 — Surrogate Endpoint (SUR): Serum potassium
Study 30239799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16949521 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 16949521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11509468 — Surrogate Endpoint (SUR): Blood pressure
Study 15539017 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20683336 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1999091 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28866864 — Surrogate Endpoint (SUR): Blood pressure
Study 22798265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22798265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19797259 — Surrogate Endpoint (SUR): Serum creatinine
Study 17457450 — Surrogate Endpoint (SUR): Bone mineral density
Study 15057903 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12101381 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 25354241 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 15208587 — Predictive Biomarker (PRD): ADAM33 mRNA
Genes: ADAM33; C20orf153; UNQ873/PRO1891
Study 11042570 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 11042570 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 11042570 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 8453963 — Surrogate Endpoint (SUR): Blood pressure
Study 29390064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29390064 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 29390064 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25937522 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25937522 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 11099655 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 31447126 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28359688 — Safety Biomarker (SAF): Hyaluronic acid
Study 9249084 — Predictive Biomarker (PRD): AGL mRNA
Genes: AGL; GDE
Study 31844967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31844967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31844967 — Surrogate Endpoint (SUR): Blood pressure
Study 31844967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26590813 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26590813 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ESR2 mRNA
Genes: ESR2; ESTRB; NR3A2
Study 26590813 — Predictive Biomarker (PRD): Hormone receptor
Study 26179201 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26179201 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23418430 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21372447 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21372447 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19927226 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 9385472 — Surrogate Endpoint (SUR): Blood pressure
Study 12560149 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 11099319 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20414546 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18341600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12430737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22179130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15508014 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15508014 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27650995 — Surrogate Endpoint (SUR): Blood pressure
Study 9118711 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7505979 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2941208 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 3327362 — Surrogate Endpoint (SUR): Blood pressure
Study 24319955 — Monitoring Biomarker (MOI): HBV DNA
Study 16517329 — Surrogate Endpoint (SUR): Blood pressure
Study 13129737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 6475561 — Surrogate Endpoint (SUR): Blood pressure
Study 2137666 — Surrogate Endpoint (SUR): Blood pressure
Study 28296744 — Surrogate Endpoint (SUR): Serum uric acid
Study 22155024 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 16267767 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10446081 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10446081 — Surrogate Endpoint (SUR): Blood pressure
Study 31707849 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31707849 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21946544 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9727573 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30958388 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 30958388 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30958388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23616509 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31755166 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18356827 — Surrogate Endpoint (SUR): Blood pressure
Study 18356827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1394142 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12584835 — Surrogate Endpoint (SUR): Blood pressure
Study 10359467 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 6281451 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19387336 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 17322151 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17322151 — Safety Biomarker (SAF): Reactive oxygen species
Study 17322151 — Surrogate Endpoint (SUR): Blood pressure
Study 18173197 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 18173197 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30550176 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26427036 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23688334 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20533245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20533245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18240282 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18240282 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 12828793 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12828793 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10751234 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24240315 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 16154486 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21608215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21608215 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 21608215 — Surrogate Endpoint (SUR): Bone mineral density
Study 23041990 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 23041990 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16153509 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27312989 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 11329107 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8673477 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31689748 — Predictive Biomarker (PRD): PERP mRNA
Genes: PERP; KCP1; KRTCAP1; PIGPC1; THW
Study 31689748 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23797608 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 11449079 — Surrogate Endpoint (SUR): Blood pressure
Study 9683204 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28224926 — Surrogate Endpoint (SUR): Blood pressure
Study 18929284 — Surrogate Endpoint (SUR): Blood pressure
Study 16470820 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11604980 — Surrogate Endpoint (SUR): Blood pressure
Study 18796620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18796620 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18796620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10433305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7717819 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 7717819 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7717819 — Surrogate Endpoint (SUR): Blood pressure
Study 28682422 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 25932899 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25932899 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25932899 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17515464 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11275935 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11275935 — Surrogate Endpoint (SUR): Blood pressure
Study 9666011 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9666011 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3