TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28833962 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 28833962 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 10685722 — Surrogate Endpoint (SUR): Blood pressure
Study 9086133 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7886561 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 30664008 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29885082 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29885082 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27622961 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27622961 — Surrogate Endpoint (SUR): Blood pressure
Study 27622961 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27622961 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29573529 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 29573529 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 29573529 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 30095728 — Surrogate Endpoint (SUR): Blood pressure
Study 24188685 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8989008 — Surrogate Endpoint (SUR): Blood pressure
Study 27993193 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27993193 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27993193 — Surrogate Endpoint (SUR): Blood pressure
Study 8151586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24335178 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24335178 — Predictive Biomarker (PRD): E2F1 mRNA
Genes: E2F1; RBBP3
Study 24335178 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-34a
Genes: MIR34A
Study 15922429 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 9040453 — Surrogate Endpoint (SUR): Blood pressure
Study 28898532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25983115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25983115 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16198072 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16198072 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27009579 — Surrogate Endpoint (SUR): Blood pressure
Study 27009579 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 506742 — Surrogate Endpoint (SUR): Blood pressure
Study 506742 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 25886483 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21167235 — Surrogate Endpoint (SUR): Serum creatinine
Study 6448210 — Surrogate Endpoint (SUR): Blood pressure
Study 14743120 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14743120 — Surrogate Endpoint (SUR): Blood pressure
Study 11201870 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26514303 — Surrogate Endpoint (SUR): Blood pressure
Study 24720535 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24720535 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24720535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22718810 — Surrogate Endpoint (SUR): Blood pressure
Study 11457420 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31774464 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 12928049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20438292 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20438292 — Surrogate Endpoint (SUR): Serum creatinine
Study 15516367 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12042887 — Surrogate Endpoint (SUR): Serum calcium
Study 2378441 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6707342 — Surrogate Endpoint (SUR): Blood pressure
Study 16583464 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 12664078 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30554092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30554092 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 1398694 — Surrogate Endpoint (SUR): Blood pressure
Study 18825655 — Surrogate Endpoint (SUR): Blood pressure
Study 10473885 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10473885 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1929683 — Surrogate Endpoint (SUR): Blood pressure
Study 1929683 — Surrogate Endpoint (SUR): Serum potassium
Study 30907562 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28045953 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 23999279 — Surrogate Endpoint (SUR): Blood pressure
Study 14689371 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14689371 — Surrogate Endpoint (SUR): Blood pressure
Study 29775461 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21415777 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 11746535 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11746535 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 11746535 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 11746535 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 11746535 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 11746535 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 3287892 — Surrogate Endpoint (SUR): Blood pressure
Study 30825389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25683266 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15020659 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 15020659 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29232592 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24736677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10323627 — Surrogate Endpoint (SUR): Blood pressure
Study 29480965 — Surrogate Endpoint (SUR): Blood pressure
Study 25444576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25444576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25444576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18629317 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16083781 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1450090 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31126574 — Surrogate Endpoint (SUR): Blood pressure
Study 28361752 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25148829 — Surrogate Endpoint (SUR): Blood pressure
Study 16335883 — Surrogate Endpoint (SUR): Blood pressure
Study 12003701 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9865456 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7711991 — Surrogate Endpoint (SUR): Blood pressure
Study 9848038 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 25538166 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 25538166 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23011357 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 24184063 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 16080809 — Surrogate Endpoint (SUR): Blood pressure
Study 23357841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11494088 — Surrogate Endpoint (SUR): Blood pressure
Study 9210750 — Surrogate Endpoint (SUR): Blood pressure
Study 31077229 — Surrogate Endpoint (SUR): Blood pressure
Study 25458463 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 19100344 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 31482956 — Surrogate Endpoint (SUR): Blood pressure
Study 19682376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15307856 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7001489 — Surrogate Endpoint (SUR): Serum potassium
Study 7001489 — Surrogate Endpoint (SUR): Blood pressure
Study 11452240 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9570605 — Surrogate Endpoint (SUR): Blood pressure
Study 7923311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9487840 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19958532 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11464426 — Monitoring Biomarker (MOI): HBV DNA
Study 30377862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30377862 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 28576734 — Surrogate Endpoint (SUR): Blood pressure
Study 26116425 — Safety Biomarker (SAF): Reactive oxygen species
Study 21663622 — Predictive Biomarker (PRD): SCAMP1 mRNA
Genes: SCAMP1; SCAMP
Study 16598443 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16598443 — Surrogate Endpoint (SUR): Blood pressure
Study 14604447 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 8505940 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18165640 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15711271 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11860783 — Surrogate Endpoint (SUR): Blood pressure
Study 8843295 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 23522247 — Monitoring Biomarker (MOI): HBV DNA
Study 18671947 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 18671947 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26216386 — Predictive Biomarker (PRD): SP5 mRNA
Genes: SP5
Study 26216386 — Predictive Biomarker (PRD): SP3 mRNA
Genes: SP3
Study 17290056 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 2475690 — Surrogate Endpoint (SUR): Blood pressure
Study 23236022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20957423 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19345767 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 8294693 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27593544 — Safety Biomarker (SAF): Reactive oxygen species
Study 24753491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24753491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19100003 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 19100003 — Surrogate Endpoint (SUR): Blood pressure
Study 30039387 — Surrogate Endpoint (SUR): Urinary oxalate
Study 28832310 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25243647 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25243647 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21831230 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16391401 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16391401 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 12428313 — Surrogate Endpoint (SUR): Blood pressure
Study 9709937 — Surrogate Endpoint (SUR): Serum testosterone
Study 24449631 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17495819 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16497822 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16497822 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16497822 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21612677 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25012289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18455592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18455592 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 9972993 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 31820604 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 31820604 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19608703 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1565535 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29289554 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28707379 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27234640 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 27234640 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 15911704 — Surrogate Endpoint (SUR): Blood pressure
Study 6538423 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22550699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7128841 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31389607 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31389607 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 31389607 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 19435740 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 17562974 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 17562974 — Surrogate Endpoint (SUR): Blood pressure
Study 31814335 — Predictive Biomarker (PRD): Tripeptidyl-peptidase I
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study 19638365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19638365 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10027935 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10027935 — Surrogate Endpoint (SUR): Blood pressure
Study 31977907 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 31977907 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 19159546 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 10500778 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 8397459 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31725697 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 25828946 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23778412 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23778412 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 23778412 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23778412 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 23778412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23778412 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25882438 — Safety Biomarker (SAF): Hyaluronic acid
Study 14605329 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 29985456 — Predictive Biomarker (PRD): PER1 mRNA
Genes: PER1; KIAA0482; PER; RIGUI
Study 29985456 — Predictive Biomarker (PRD): PER2 mRNA
Genes: PER2; KIAA0347
Study 29985456 — Predictive Biomarker (PRD): BMAL1 mRNA
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 22068670 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22068670 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 22068670 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7484887 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7484887 — Surrogate Endpoint (SUR): Blood pressure
Study 31756675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31398441 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31398441 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 28433216 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28433216 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26372318 — Surrogate Endpoint (SUR): Blood pressure
Study 21891773 — Surrogate Endpoint (SUR): Serum creatinine
Study 10743479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 7723371 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 7723371 — Safety Biomarker (SAF): Hyaluronic acid
Study 27103467 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24947926 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 16433710 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16433710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1872664 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28058962 — Safety Biomarker (SAF): Hyaluronic acid
Study 23475164 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19407730 — Surrogate Endpoint (SUR): Blood pressure
Study 28686675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19246990 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15157947 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 24123600 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 14674504 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 11306153 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 9736326 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 165796 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 22008766 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14592559 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11071403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24072776 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18035131 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15569865 — Surrogate Endpoint (SUR): Blood pressure
Study 8847017 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23422652 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31350928 — Surrogate Endpoint (SUR): Bone mineral density
Study 17602983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17602983 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 2695500 — Predictive Biomarker (PRD): SRY mRNA
Genes: SRY; TDF
Study 19356914 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 23597577 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19302423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14749346 — Surrogate Endpoint (SUR): Blood pressure
Study 2907743 — Surrogate Endpoint (SUR): Blood pressure
Study 29780829 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 19281927 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15123220 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31250099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31250099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31250099 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30987658 — Surrogate Endpoint (SUR): Blood pressure
Study 26332857 — Surrogate Endpoint (SUR): Blood pressure
Study 23320520 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 21502898 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11008329 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22801130 — Surrogate Endpoint (SUR): Blood pressure
Study 18564802 — Surrogate Endpoint (SUR): Blood pressure
Study 16372827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1540479 — Surrogate Endpoint (SUR): Blood pressure
Study 11180494 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31230026 — Surrogate Endpoint (SUR): Bone mineral density
Study 29151036 — Surrogate Endpoint (SUR): Blood pressure
Study 25591555 — Surrogate Endpoint (SUR): Blood pressure