TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11180995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22033466 — Predictive Biomarker (PRD): S100A2 mRNA
Genes: S100A2; S100L
Study 22033466 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22033466 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29499122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27576780 — Surrogate Endpoint (SUR): Blood pressure
Study 31283409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24678649 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25129066 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 25129066 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19706577 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 17519435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9808101 — Surrogate Endpoint (SUR): Serum creatinine
Study 989378 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31292190 — Surrogate Endpoint (SUR): Blood pressure
Study 24257393 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17708740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1700551 — Monitoring Biomarker (MOI): HBV DNA
Study 30658933 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28572633 — Surrogate Endpoint (SUR): Blood pressure
Study 16829095 — Monitoring Biomarker (MOI): Complement C4
Study 16829095 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21803869 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 11883765 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7767515 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 2152662 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2152662 — Surrogate Endpoint (SUR): Blood pressure
Study 31124581 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25464226 — Predictive Biomarker (PRD): ETV3 mRNA
Genes: ETV3; METS; PE1
Study 15090972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9342788 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 9342788 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 2956876 — Surrogate Endpoint (SUR): Blood pressure
Study 27208905 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27208905 — Surrogate Endpoint (SUR): Pathological complete response
Study 22413441 — Surrogate Endpoint (SUR): Blood pressure
Study 15958063 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 12410858 — Surrogate Endpoint (SUR): Serum creatinine
Study 27128357 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15863798 — Surrogate Endpoint (SUR): Blood pressure
Study 2109522 — Surrogate Endpoint (SUR): Blood pressure
Study 30990777 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 9390584 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9390584 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28593473 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study 23591157 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23591157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19444535 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 30082217 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9177625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23065358 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23065358 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21392602 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 2941052 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 27358493 — Predictive Biomarker (PRD): TFAM mRNA
Genes: TFAM; TCF6; TCF6L2
Study 18451243 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12574177 — Surrogate Endpoint (SUR): Bone mineral density
Study 30842172 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 21767239 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 19649993 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 15181616 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 30043678 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26065565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9206085 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31964450 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31810342 — Surrogate Endpoint (SUR): Blood pressure
Study 31810342 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31810342 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30048574 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25439407 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25439407 — Surrogate Endpoint (SUR): Blood pressure
Study 19176733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7999459 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23921143 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 15460358 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 2612087 — Surrogate Endpoint (SUR): Blood pressure
Study 26279073 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26279073 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20521076 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 18805524 — Surrogate Endpoint (SUR): Bone mineral density
Study 9886891 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9886891 — Surrogate Endpoint (SUR): Blood pressure
Study 27050662 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27050662 — Surrogate Endpoint (SUR): Blood pressure
Study 23290018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23290018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23290018 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 3122065 — Surrogate Endpoint (SUR): Blood pressure
Study 29976277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29976277 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23846158 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8133537 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 2683543 — Surrogate Endpoint (SUR): Blood pressure
Study 2683543 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29785889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29785889 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 29785889 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29785889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19187286 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25608632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3442398 — Surrogate Endpoint (SUR): Blood pressure
Study 3519644 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 22836585 — Surrogate Endpoint (SUR): Bone mineral density
Study 21729676 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21729676 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21729676 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12742282 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 12742282 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 12742282 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 12742282 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 12742282 — Predictive Biomarker (PRD): CCR1 mRNA
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 29081351 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 27560289 — Safety Biomarker (SAF): Hyaluronic acid
Study 24343370 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 24343370 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 23700945 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 3519241 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3519241 — Surrogate Endpoint (SUR): Blood pressure
Study 3519241 — Surrogate Endpoint (SUR): Serum uric acid
Study 12426230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12426230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12426230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12426230 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12426230 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 12426230 — Safety Biomarker (SAF): Interleukin 12
Study 7708993 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26174611 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8785033 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1548988 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21422713 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8580577 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22622962 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22622962 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15863647 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 30144304 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 30144304 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20527138 — Safety Biomarker (SAF): Hyaluronic acid
Study 16043680 — Surrogate Endpoint (SUR): Bone mineral density
Study 15228673 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3257288 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 3257288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3257288 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 24042991 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 9262882 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23539236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10583449 — Surrogate Endpoint (SUR): Blood pressure
Study 2021138 — Surrogate Endpoint (SUR): Bone mineral density
Study 27317302 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23016532 — Safety Biomarker (SAF): Hyaluronic acid
Study 7630132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7630132 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 7630132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27277839 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25087673 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12812387 — Surrogate Endpoint (SUR): Blood pressure
Study 9524046 — Surrogate Endpoint (SUR): Blood pressure
Study 30825384 — Surrogate Endpoint (SUR): Probing pocket depth
Study 27139422 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 27139422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27139422 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27139422 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27139422 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22094353 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17704022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27810904 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 25191546 — Surrogate Endpoint (SUR): Blood pressure
Study 19875397 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 2141488 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 271171 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23925361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23925361 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 23925361 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23925361 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21324133 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17061611 — Surrogate Endpoint (SUR): Serum calcium
Study 17061611 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2493897 — Surrogate Endpoint (SUR): Blood pressure
Study 25645599 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21336094 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 19859560 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 15249511 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 15249511 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29848412 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 21837478 — Predictive Biomarker (PRD): Hormone receptor
Study 18802363 — Surrogate Endpoint (SUR): Serum calcium
Study 11214778 — Surrogate Endpoint (SUR): Blood pressure
Study 30198318 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30198318 — Safety Biomarker (SAF): Interleukin 1
Study 30198318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30198318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27251956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19967459 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 15746824 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15746824 — Surrogate Endpoint (SUR): Blood pressure
Study 12975259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12975259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10648308 — Surrogate Endpoint (SUR): Blood pressure
Study 6196073 — Surrogate Endpoint (SUR): Serum potassium
Study 17127441 — Safety Biomarker (SAF): Reactive oxygen species
Study 9513613 — Surrogate Endpoint (SUR): Bone mineral density
Study 28272972 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 30485853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26211002 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 9432046 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9432046 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24523037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15654581 — Surrogate Endpoint (SUR): Bone mineral density
Study 8986438 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 23875876 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 22111662 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22111662 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22111662 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 12368396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12368396 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 31642984 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 31642984 — Surrogate Endpoint (SUR): Blood pressure
Study 31150439 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 26494348 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 15219176 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7875638 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 7875638 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 7875638 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 7875638 — Predictive Biomarker (PRD): BANF1 mRNA
Genes: BANF1; BAF; BCRG1
Study 7875638 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 7875638 — Predictive Biomarker (PRD): BLVRA mRNA
Genes: BLVRA; BLVR; BVR
Study 7875638 — Surrogate Endpoint (SUR): Blood pressure
Study 24237037 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 11939988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11939988 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18950770 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18950770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18950770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18950770 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17201798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31954775 — Safety Biomarker (SAF): Th2 cell
Study 16972680 — Surrogate Endpoint (SUR): Bone mineral density
Study 12799555 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12799555 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2193856 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30773747 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 28128473 — Safety Biomarker (SAF): Hyaluronic acid
Study 22035351 — Surrogate Endpoint (SUR): Blood pressure
Study 12619182 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28577105 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28577105 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28577105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16998653 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 8696719 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 16814130 — Surrogate Endpoint (SUR): Blood pressure
Study 8882841 — Surrogate Endpoint (SUR): Blood pressure
Study 1370509 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20451538 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 20451538 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 17947341 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17947341 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12842747 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 12842747 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 10381282 — Safety Biomarker (SAF): MTHFR
Study 10381282 — Surrogate Endpoint (SUR): Serum creatinine
Study 10381282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 6682617 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28885231 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 25265449 — Surrogate Endpoint (SUR): Serum creatinine
Study 20406686 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20406686 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 20406686 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 9143253 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23835112 — Surrogate Endpoint (SUR): Blood pressure
Study 23835112 — Safety Biomarker (SAF): Reactive oxygen species
Study 23835112 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1