TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19669729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19669729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19670189 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 19679693 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19679883 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19685102 — Surrogate Endpoint (SUR): Blood pressure
Study 19689789 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 19695539 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19696651 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19703304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19706858 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19706886 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 19706886 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 19707564 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 19714615 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 19716045 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 19716045 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19717473 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 19717473 — Predictive Biomarker (PRD): LTA4H mRNA
Genes: LTA4H; LTA4
Study 19718477 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 19718477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19718477 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19720904 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 19720923 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19720923 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19726763 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study 19726763 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH
Study 19727007 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19727007 — Surrogate Endpoint (SUR): Blood pressure
Study 19727007 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19727208 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19727208 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19727208 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19727208 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19727657 — Predictive Biomarker (PRD): RETN mRNA
Genes: RETN; FIZZ3; HXCP1; RSTN; UNQ407/PRO1199
Study 19727665 — Predictive Biomarker (PRD): AGPAT2 mRNA
Genes: AGPAT2
Study 19727665 — Predictive Biomarker (PRD): BSCL2 mRNA
Genes: BSCL2
Study 19727665 — Predictive Biomarker (PRD): LMNA mRNA
Genes: LMNA; LMN1
Study 19727665 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 19729666 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 19729666 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19729666 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 19729666 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 19729666 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 19729666 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 19734762 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19738484 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19740906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19740906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19752173 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 19752422 — Surrogate Endpoint (SUR): Blood pressure
Study 19752530 — Surrogate Endpoint (SUR): Serum uric acid
Study 19757984 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19760338 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 19766264 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19770418 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19771175 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 19771508 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19771508 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19773266 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19773266 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19775921 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 19779040 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 19779040 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 19780860 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 19782361 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19786617 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 19786617 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 19789316 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 19796970 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19797219 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19797219 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 19801505 — Predictive Biomarker (PRD): Liver iron
Study 19802383 — Predictive Biomarker (PRD): FAM53B mRNA
Genes: FAM53B; KIAA0140; SMP
Study 19809305 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19809365 — Surrogate Endpoint (SUR): Blood pressure
Study 19811637 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 19816190 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 19816190 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19816412 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19822896 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 19822896 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 19828038 — Surrogate Endpoint (SUR): Serum uric acid
Study 19828712 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 19828714 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 19828715 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19833996 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 19837914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19837914 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19837914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19838774 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 19838774 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 19838774 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 19850844 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 19850844 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 19850844 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19850844 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 19850844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 19852963 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 19852963 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19854499 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 19854509 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 19854509 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19857703 — Surrogate Endpoint (SUR): Blood pressure
Study 19857703 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19858149 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 19858149 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 19858725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19858725 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19863224 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19863224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19863224 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 19863224 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 19864401 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 19875605 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19880498 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 19882497 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19886987 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19887595 — Safety Biomarker (SAF): Nicotinamide phosphoribosyltransferase
Genes: NAMPT; PBEF; PBEF1
Study 19887595 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 19887595 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 19888782 — Surrogate Endpoint (SUR): Serum testosterone
Study 19889819 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 19890203 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19909496 — Surrogate Endpoint (SUR): Bone mineral density
Study 19915292 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 19915292 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 19915292 — Surrogate Endpoint (SUR): Bone mineral density
Study 19917888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19917888 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19920114 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 19920819 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19920819 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 19920819 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19922035 — Surrogate Endpoint (SUR): Blood pressure
Study 19922631 — Surrogate Endpoint (SUR): Blood pressure
Study 19923369 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19923475 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19926602 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19929182 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19930156 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 19930156 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19932729 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19933192 — Surrogate Endpoint (SUR): Blood pressure
Study 19933938 — Surrogate Endpoint (SUR): Serum creatinine
Study 19933994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19933994 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19939200 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 19939200 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19939200 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 19946413 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19946413 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 19950084 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19951974 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19951974 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 19951974 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 19952143 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19962985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19965642 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study 19965642 — Predictive Biomarker (PRD): RORA
Genes: RZRA; ROR1; ROR2; ROR3; NR1F1; ROR-alpha; RORalpha; RORa1
Study 19965642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19965662 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 19996412 — Predictive Biomarker (PRD): Liver iron
Study 20001658 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20001856 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20003269 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 20003457 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20003832 — Predictive Biomarker (PRD): Hormone receptor
Study 20004787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20004787 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20007560 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20007560 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20007560 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 20007809 — Surrogate Endpoint (SUR): Serum asparaginase
Study 20008298 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 20008298 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 20010317 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 20018959 — Predictive Biomarker (PRD): MMP12 mRNA
Genes: MMP12; HME
Study 20019013 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 20023246 — Safety Biomarker (SAF): Hyaluronic acid
Study 20028332 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20028530 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 20031382 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20031619 — Predictive Biomarker (PRD): MYH7 mRNA
Genes: MYH7; MYHCB
Study 20031619 — Predictive Biomarker (PRD): ACTC1 mRNA
Genes: ACTC1; ACTC
Study 20031619 — Safety Biomarker (SAF): Cardiac troponin T
Genes: TNNT2
Study 20031619 — Predictive Biomarker (PRD): MYBPC3 mRNA
Genes: MYBPC3
Study 20032495 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 20032495 — Predictive Biomarker (PRD): ADIPOR2 mRNA
Genes: ADIPOR2; PAQR2
Study 20034959 — Surrogate Endpoint (SUR): Blood pressure
Study 20034959 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20038731 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 20038731 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 20038731 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 20038754 — Surrogate Endpoint (SUR): Blood pressure
Study 20039404 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 20051022 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 20051022 — Surrogate Endpoint (SUR): Blood pressure
Study 20051130 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 20056794 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 20057899 — Surrogate Endpoint (SUR): Blood pressure
Study 20060484 — Monitoring Biomarker (MOI): HBV DNA
Study 20061136 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20061136 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20064072 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 20064072 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20064208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20064208 — Surrogate Endpoint (SUR): Blood pressure
Study 20064208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20064208 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20065758 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20065758 — Safety Biomarker (SAF): Interleukin 1
Study 20065758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20067838 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20067838 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 20075384 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20078436 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 20080236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20081096 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20082929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20082929 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20087581 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 20087581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20090835 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 20090916 — Predictive Biomarker (PRD): CD244 mRNA
Genes: CD244; 2B4
Study 20090916 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 20092642 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 20093349 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 20095074 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20098694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20106720 — Surrogate Endpoint (SUR): Pathological complete response
Study 20107229 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20107229 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20109568 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 20110053 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 20112381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20121884 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 20121884 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20124123 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20126394 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20126394 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20128887 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 20129551 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20130244 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 20130244 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20133895 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 20136164 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20136164 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20139093 — Predictive Biomarker (PRD): CRLF2 mRNA
Genes: CRLF2; CRL2; ILXR; TSLPR
Study 20139093 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 20139093 — Predictive Biomarker (PRD): P2RY8 mRNA
Genes: P2RY8
Study 20139093 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 20139093 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 20139774 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 20139774 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20142724 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20142724 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 20149262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 20149262 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20149262 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20149736 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 20152220 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20157193 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 20157193 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 20170786 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 20173748 — Predictive Biomarker (PRD): FAM13A mRNA
Genes: FAM13A; FAM13A1; KIAA0914
Study 20176858 — Predictive Biomarker (PRD): ACSL1 mRNA
Genes: ACSL1; FACL1; FACL2; LACS; LACS1; LACS2
Study 20176990 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20178723 — Surrogate Endpoint (SUR): Blood pressure
Study 20178723 — Surrogate Endpoint (SUR): Serum creatinine
Study 20179614 — Monitoring Biomarker (MOI): HBV DNA
Study 20180805 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2