TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27496969 — Predictive Biomarker (PRD): TAFA4 mRNA
Genes: TAFA4; FAM19A4
Study 27496969 — Predictive Biomarker (PRD): PHACTR3 mRNA
Genes: PHACTR3; C20orf101; SCAPIN1
Study 26028494 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 23459398 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 21355149 — Surrogate Endpoint (SUR): Bone mineral density
Study 9641175 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 766567 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 766567 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30769272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30769272 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27098676 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 19036079 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 19036079 — Safety Biomarker (SAF): CDA
Genes: CDD
Study 15300807 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18683001 — Surrogate Endpoint (SUR): Blood pressure
Study 17062681 — Safety Biomarker (SAF): Interleukin 12
Study 7554393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7554393 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 7554393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7554393 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 17158441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17158441 — Surrogate Endpoint (SUR): Blood pressure
Study 10945421 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 8134738 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 2824365 — Surrogate Endpoint (SUR): Blood pressure
Study 31036563 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26507862 — Predictive Biomarker (PRD): BMP7 mRNA
Genes: BMP7; OP1
Study 22933541 — Surrogate Endpoint (SUR): Serum calcium
Study 20816189 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20816189 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 20816189 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 18453796 — Surrogate Endpoint (SUR): Blood pressure
Study 18453796 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7315832 — Surrogate Endpoint (SUR): Blood pressure
Study 28445659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25537159 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17492951 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 17492951 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17492951 — Predictive Biomarker (PRD): Hormone receptor
Study 1089446 — Surrogate Endpoint (SUR): Blood pressure
Study 1089446 — Surrogate Endpoint (SUR): Serum potassium
Study 15201658 — Surrogate Endpoint (SUR): Serum creatinine
Study 19645039 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19645039 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17917830 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17917830 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11180763 — Surrogate Endpoint (SUR): Pathological complete response
Study 20047622 — Surrogate Endpoint (SUR): Blood pressure
Study 30458734 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 10757573 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1516509 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30827929 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 22008269 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 11669407 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11669407 — Surrogate Endpoint (SUR): Blood pressure
Study 31441407 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 24277510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16920140 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24886536 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 21933330 — Surrogate Endpoint (SUR): Blood pressure
Study 19684412 — Surrogate Endpoint (SUR): Blood pressure
Study 17412579 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3499244 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28222525 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23505907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16818281 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29378998 — Safety Biomarker (SAF): Hyaluronic acid
Study 21205136 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 25908506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25908506 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25908506 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16750455 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 7988251 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 24648723 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24648723 — Safety Biomarker (SAF): BDNF
Study 18076246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18076246 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8930940 — Predictive Biomarker (PRD): GCSAM mRNA
Genes: GCSAM; GAL; GCET2
Study 8930940 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 8930940 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8930940 — Surrogate Endpoint (SUR): Blood pressure
Study 6132819 — Surrogate Endpoint (SUR): Blood pressure
Study 19362675 — Surrogate Endpoint (SUR): Bone mineral density
Study 16339095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7577781 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 2034479 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31907024 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 31907024 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 27266853 — Surrogate Endpoint (SUR): Blood pressure
Study 20499072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20499072 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 20499072 — Surrogate Endpoint (SUR): Blood pressure
Study 16531164 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 16531164 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 3157576 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22503790 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 9253321 — Surrogate Endpoint (SUR): Bone mineral density
Study 29772657 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29772657 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15727954 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11990404 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21174144 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19581353 — Surrogate Endpoint (SUR): Bone mineral density
Study 9256938 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9256938 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31235428 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 15077288 — Surrogate Endpoint (SUR): Bone mineral density
Study 12153607 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7082858 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 31398275 — Predictive Biomarker (PRD): HDAC8 mRNA
Genes: HDAC8; HDACL1; CDA07
Study 29464691 — Safety Biomarker (SAF): Reactive oxygen species
Study 29464691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24628390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20555373 — Surrogate Endpoint (SUR): Blood pressure
Study 3570421 — Surrogate Endpoint (SUR): Blood pressure
Study 24318038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21374068 — Surrogate Endpoint (SUR): Bone mineral density
Study 18979504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18979504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18979504 — Predictive Biomarker (PRD): PLIN2 mRNA
Genes: PLIN2; ADFP
Study 18979504 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 18979504 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18979504 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 14738235 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 9661678 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7923825 — Surrogate Endpoint (SUR): Blood pressure
Study 2894902 — Surrogate Endpoint (SUR): Blood pressure
Study 28375559 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 15863522 — Surrogate Endpoint (SUR): Blood pressure
Study 31561715 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 28375792 — Safety Biomarker (SAF): Hyaluronic acid
Study 28375792 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 28551092 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 21841500 — Surrogate Endpoint (SUR): Blood pressure
Study 19123865 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7972620 — Surrogate Endpoint (SUR): Blood pressure
Study 28915907 — Surrogate Endpoint (SUR): Blood pressure
Study 23051870 — Predictive Biomarker (PRD): NELFCD mRNA
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 23051870 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 17674017 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 16549931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12759270 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8500312 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 30970404 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 30970404 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30970404 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 27696203 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study 19155235 — Surrogate Endpoint (SUR): Serum creatinine
Study 19155235 — Surrogate Endpoint (SUR): Blood pressure
Study 18071724 — Safety Biomarker (SAF): Reactive oxygen species
Study 1974677 — Surrogate Endpoint (SUR): Blood pressure
Study 31927126 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 31927126 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22083332 — Surrogate Endpoint (SUR): Serum testosterone
Study 15986873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31996543 — Surrogate Endpoint (SUR): Blood pressure
Study 9447854 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9447854 — Surrogate Endpoint (SUR): Blood pressure
Study 348378 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11860403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 619938 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 12448067 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12448067 — Surrogate Endpoint (SUR): Blood pressure
Study 19910654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15151941 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22934396 — Surrogate Endpoint (SUR): Blood pressure
Study 12466165 — Surrogate Endpoint (SUR): Blood pressure
Study 30784354 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 30784354 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 28213565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28213565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22475140 — Monitoring Biomarker (MOI): HBV DNA
Study 7968423 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7968423 — Surrogate Endpoint (SUR): Blood pressure
Study 15119922 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 11231440 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 11231440 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8176138 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 4400530 — Surrogate Endpoint (SUR): Blood pressure
Study 31371154 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30712955 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28369078 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28369078 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 28369078 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 23704939 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 23704939 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 16440917 — Surrogate Endpoint (SUR): Blood pressure
Study 7484285 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 7484285 — Surrogate Endpoint (SUR): Serum calcium
Study 18321680 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 18321680 — Predictive Biomarker (PRD): C6orf15 mRNA
Genes: C6orf15; STG; UNQ1840/PRO3566
Study 18321680 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 14585761 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 1457788 — Surrogate Endpoint (SUR): Blood pressure
Study 2127335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31006038 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 1758944 — Surrogate Endpoint (SUR): Blood pressure
Study 24480430 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24480430 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20807120 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DMRT1 mRNA
Genes: DMRT1; DMT1
Study 15768872 — Surrogate Endpoint (SUR): Blood pressure
Study 12191719 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 7797216 — Surrogate Endpoint (SUR): Blood pressure
Study 3134082 — Surrogate Endpoint (SUR): Blood pressure
Study 22420471 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12351435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12351435 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31464626 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12040670 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12568173 — Surrogate Endpoint (SUR): Blood pressure
Study 7553996 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7553996 — Surrogate Endpoint (SUR): Blood pressure
Study 27150635 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 27150635 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10207807 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 7599914 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2221406 — Surrogate Endpoint (SUR): Blood pressure
Study 23807528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22046394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16476841 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12771010 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10677157 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10677157 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10619727 — Surrogate Endpoint (SUR): Serum creatinine
Study 28077140 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26025128 — Predictive Biomarker (PRD): TBCD mRNA
Genes: TBCD; KIAA0988; SSD1; TFCD; PP1096
Study 21225278 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21225278 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21225278 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7987084 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31366355 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 2864845 — Surrogate Endpoint (SUR): Blood pressure
Study 22967772 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 22967772 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 22967772 — Predictive Biomarker (PRD): HTR2C mRNA
Genes: HTR2C; HTR1C
Study 22967772 — Safety Biomarker (SAF): DRD2
Study 2200924 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2200924 — Surrogate Endpoint (SUR): Blood pressure
Study 31759092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31759092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8457524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3721646 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30138966 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 30138966 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 19292064 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3511392 — Surrogate Endpoint (SUR): Blood pressure
Study 29982277 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 11130159 — Predictive Biomarker (PRD): DDX53 mRNA
Genes: DDX53; CAGE
Study 27041672 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 27041672 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27041672 — Predictive Biomarker (PRD): ALDH1A1 mRNA
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study 8106625 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 19663128 — Predictive Biomarker (PRD): VIT mRNA
Genes: VIT; UNQ647/PRO1277
Study 2671617 — Surrogate Endpoint (SUR): Blood pressure
Study 2671617 — Surrogate Endpoint (SUR): Serum potassium
Study 23287638 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 23287638 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 7639365 — Surrogate Endpoint (SUR): Blood pressure
Study 30674430 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23415313 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 21154196 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 2859871 — Surrogate Endpoint (SUR): Blood pressure
Study 27626473 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27592520 — Surrogate Endpoint (SUR): Blood pressure
Study 23917748 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 23917748 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8360391 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 2875439 — Surrogate Endpoint (SUR): Blood pressure
Study 15562020 — Surrogate Endpoint (SUR): Serum testosterone
Study 1695049 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31209192 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23786282 — Predictive Biomarker (PRD): ZAP70 mRNA
Genes: ZAP70; SRK
Study 23786282 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9272403 — Surrogate Endpoint (SUR): Blood pressure
Study 24502842 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 22172428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20420510 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25416193 — Surrogate Endpoint (SUR): Blood pressure
Study 16718629 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15337695 — Surrogate Endpoint (SUR): Serum creatinine
Study 19487269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19487269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 19487269 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 19487269 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19487269 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 1425726 — Surrogate Endpoint (SUR): Serum creatinine