TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24975892 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 15287853 — Monitoring Biomarker (MOI): HBV DNA
Study 1583328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1583328 — Safety Biomarker (SAF): Interleukin 1
Study 24480867 — Surrogate Endpoint (SUR): Blood pressure
Study 19922752 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25616223 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25616223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25616223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25616223 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25616223 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21221770 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26890171 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20509987 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18371962 — Surrogate Endpoint (SUR): Serum sodium
Study 31307844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29218448 — Surrogate Endpoint (SUR): Blood pressure
Study 24782426 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17689737 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28845523 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27029704 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27029704 — Predictive Biomarker (PRD): Hormone receptor
Study 23430192 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 18256777 — Surrogate Endpoint (SUR): Bone mineral density
Study 18256777 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8638521 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1658138 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 31332918 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 29022084 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11113067 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27604620 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study 27604620 — Predictive Biomarker (PRD): CNTNAP2 mRNA
Genes: CNTNAP2; CASPR2; KIAA0868
Study 27604620 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23061642 — Surrogate Endpoint (SUR): Blood pressure
Study 10412782 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21402493 — Surrogate Endpoint (SUR): Blood pressure
Study 17513395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17513395 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7552478 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7040492 — Surrogate Endpoint (SUR): Blood pressure
Study 27552000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21982723 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12838187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11113749 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 9007183 — Surrogate Endpoint (SUR): Blood pressure
Study 28479233 — Predictive Biomarker (PRD): Hormone receptor
Study 23078573 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29701038 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 25701449 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 20872709 — Monitoring Biomarker (MOI): HBV DNA
Study 9322562 — Surrogate Endpoint (SUR): Bone mineral density
Study 8228631 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8228631 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8228631 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28737464 — Surrogate Endpoint (SUR): Blood pressure
Study 11782642 — Surrogate Endpoint (SUR): Bone mineral density
Study 21257798 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 21257798 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 20016232 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study 12874502 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 10898675 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6513774 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6513774 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30112318 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 20339099 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9989680 — Surrogate Endpoint (SUR): Blood pressure
Study 7369170 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10737167 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3924399 — Predictive Biomarker (PRD): SHD mRNA
Genes: SHD
Study 3924399 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 31982170 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31982170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24051496 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 14613287 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 14613287 — Surrogate Endpoint (SUR): Bone mineral density
Study 7060034 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 30715732 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 30085138 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 27538799 — Surrogate Endpoint (SUR): Serum sodium
Study 9003882 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18936569 — Surrogate Endpoint (SUR): Serum creatinine
Study 18936569 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16101168 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 10510925 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30501868 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 30501868 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 30501868 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 28775182 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 10333895 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17227715 — Surrogate Endpoint (SUR): Blood pressure
Study 12409969 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15026868 — Surrogate Endpoint (SUR): Blood pressure
Study 21545981 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21545981 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21545981 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19516150 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 12145060 — Surrogate Endpoint (SUR): Blood pressure
Study 10022399 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 10022399 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 7417123 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23157710 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 23157710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21372737 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2963525 — Surrogate Endpoint (SUR): Blood pressure
Study 11739071 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 14639446 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17698901 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12771037 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23320436 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19145494 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 3894589 — Surrogate Endpoint (SUR): Serum creatinine
Study 30977393 — Predictive Biomarker (PRD): Hormone receptor
Study 27328954 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 24336385 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18971523 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18971523 — Surrogate Endpoint (SUR): Blood pressure
Study 18971523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10999803 — Surrogate Endpoint (SUR): Serum testosterone
Study 31424649 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31424649 — Predictive Biomarker (PRD): TP53BP2 mRNA
Genes: TP53BP2; ASPP2; BBP
Study 21793378 — Predictive Biomarker (PRD): AIFM1 mRNA
Genes: AIFM1; AIF; PDCD8
Study 21793378 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 12012943 — Surrogate Endpoint (SUR): Blood pressure
Study 2194032 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2194032 — Surrogate Endpoint (SUR): Blood pressure
Study 27759579 — Surrogate Endpoint (SUR): Blood pressure
Study 23599118 — Safety Biomarker (SAF): Interleukin 1
Study 16445701 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 27738812 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27738812 — Surrogate Endpoint (SUR): Blood pressure
Study 15850466 — Monitoring Biomarker (MOI): HBV DNA
Study 7587975 — Surrogate Endpoint (SUR): Blood pressure
Study 29526502 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29526502 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24726098 — Surrogate Endpoint (SUR): Blood pressure
Study 20922537 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 20922537 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15752954 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 15752954 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15752954 — Predictive Biomarker (PRD): ADCY10 mRNA
Genes: ADCY10; SAC
Study 6522132 — Surrogate Endpoint (SUR): Blood pressure
Study 20368505 — Surrogate Endpoint (SUR): Blood pressure
Study 30923094 — Surrogate Endpoint (SUR): Hematologic response
Study 17173959 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 14739855 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 14739855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25873729 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 16330117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16330117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15053241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11424113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11424113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3551507 — Surrogate Endpoint (SUR): Blood pressure
Study 29728364 — Surrogate Endpoint (SUR): Serum creatinine
Study 25963351 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25963351 — Surrogate Endpoint (SUR): Blood pressure
Study 18288935 — Surrogate Endpoint (SUR): Blood pressure
Study 16772796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9160820 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21632497 — Surrogate Endpoint (SUR): Blood pressure
Study 18326958 — Surrogate Endpoint (SUR): Blood pressure
Study 31994262 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 29332135 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23936756 — Surrogate Endpoint (SUR): Blood pressure
Study 18284434 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16502177 — Surrogate Endpoint (SUR): Serum creatinine
Study 8380606 — Surrogate Endpoint (SUR): Blood pressure
Study 3490559 — Surrogate Endpoint (SUR): Serum calcium
Study 17209786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17209786 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10869918 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10869918 — Surrogate Endpoint (SUR): Blood pressure
Study 9375480 — Safety Biomarker (SAF): IL-6 and IL-10
Study 30226889 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 23161345 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 23161345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23161345 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 23161345 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23161345 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 23161345 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 23161345 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 20594781 — Surrogate Endpoint (SUR): Blood pressure
Study 9566550 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23697602 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21294998 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17353512 — Surrogate Endpoint (SUR): Blood pressure
Study 29101186 — Surrogate Endpoint (SUR): Blood pressure
Study 31093952 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9658616 — Monitoring Biomarker (MOI): HBV DNA
Study 17166396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17166396 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 1390605 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29972757 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 23242584 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 23242584 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23242584 — Predictive Biomarker (PRD): Hormone receptor
Study 14574515 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11737926 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17671394 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11919305 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11919305 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9949315 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23864006 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19196673 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19196673 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19196673 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19196673 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15212355 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 12914551 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 11603418 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1592448 — Surrogate Endpoint (SUR): Blood pressure
Study 6370155 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30288843 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 25009402 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29846630 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 21178937 — Surrogate Endpoint (SUR): Blood pressure
Study 17215848 — Surrogate Endpoint (SUR): Blood pressure
Study 1272739 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 28566524 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 28566524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25862517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19921983 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 16432265 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 9039547 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23954085 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18671147 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9864001 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9864001 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9864001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23954165 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 16774103 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14728888 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20381672 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15990457 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 15990457 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15526508 — Surrogate Endpoint (SUR): Blood pressure
Study 7782727 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7782727 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21807759 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 24225233 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15789123 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19189940 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 16925952 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 16925952 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 12698087 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 12698087 — Surrogate Endpoint (SUR): Serum creatinine
Study 8637441 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 1455006 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1455006 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30248943 — Surrogate Endpoint (SUR): Blood pressure
Study 23922377 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8004580 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2509214 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25103176 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22674570 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 22674570 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22674570 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22674570 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19597081 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 11718678 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9752889 — Surrogate Endpoint (SUR): Blood pressure
Study 2455740 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 2455740 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26259542 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18365224 — Safety Biomarker (SAF): Hyaluronic acid
Study 27563670 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 27563670 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 16059992 — Safety Biomarker (SAF): Reactive oxygen species
Study 6469443 — Surrogate Endpoint (SUR): Blood pressure
Study 21179732 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16188898 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16188898 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 1705274 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31116114 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 20094823 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 20094823 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 19232940 — Surrogate Endpoint (SUR): Blood pressure
Study 11427213 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 11427213 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11427213 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11427213 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18667807 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17141859 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30036739 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24977690 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study 16002965 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 12218525 — Surrogate Endpoint (SUR): Blood pressure
Study 8725976 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1890156 — Surrogate Endpoint (SUR): Blood pressure