TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12201623 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9883316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9883316 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9883316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9883316 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8722434 — Surrogate Endpoint (SUR): Blood pressure
Study 8722434 — Surrogate Endpoint (SUR): Serum sodium
Study 8722434 — Surrogate Endpoint (SUR): Serum creatinine
Study 8722434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8722434 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31733764 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 1334820 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 6373303 — Surrogate Endpoint (SUR): Blood pressure
Study 30558396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1930859 — Surrogate Endpoint (SUR): Blood pressure
Study 26992096 — Surrogate Endpoint (SUR): Serum creatinine
Study 24397109 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 24397109 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21564441 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21564441 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21564441 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21564441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18492831 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16804018 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 16804018 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 12654667 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10767192 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 17394179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31041683 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28286842 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23359344 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 23359344 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 23359344 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 10607685 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 10607685 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 2429120 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 9158082 — Surrogate Endpoint (SUR): Blood pressure
Study 27982344 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23688323 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 23688323 — Safety Biomarker (SAF): Th2 cell
Study 17429316 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11561215 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26520169 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25601227 — Safety Biomarker (SAF): Hyaluronic acid
Study 15055252 — Surrogate Endpoint (SUR): Blood pressure
Study 24215592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21455122 — Surrogate Endpoint (SUR): Blood pressure
Study 17766602 — Surrogate Endpoint (SUR): Blood pressure
Study 11495047 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15216404 — Surrogate Endpoint (SUR): Blood pressure
Study 12470761 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 636912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26064990 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 26064990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9290300 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8329700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2731601 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24072224 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 2949672 — Surrogate Endpoint (SUR): Blood pressure
Study 18178947 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 18178947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16189338 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19626043 — Surrogate Endpoint (SUR): Blood pressure
Study 25773757 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 29421993 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29421993 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29421993 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 29421993 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29421993 — Safety Biomarker (SAF): BDNF
Study 22143109 — Surrogate Endpoint (SUR): Blood pressure
Study 8665630 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31826853 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31826853 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26742981 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2881897 — Surrogate Endpoint (SUR): Blood pressure
Study 8695090 — Surrogate Endpoint (SUR): Blood pressure
Study 29282098 — Surrogate Endpoint (SUR): Serum potassium
Study 23912284 — Surrogate Endpoint (SUR): Serum sodium
Study 17241184 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17241184 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17241184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9506732 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 9506732 — Surrogate Endpoint (SUR): Bone mineral density
Study 6793609 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31146380 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28104105 — Surrogate Endpoint (SUR): Blood pressure
Study 29363990 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 27301220 — Surrogate Endpoint (SUR): Bone mineral density
Study 22282868 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 18768436 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18768436 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18768436 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 1670598 — Surrogate Endpoint (SUR): Blood pressure
Study 29769827 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29769827 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 23276436 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23276436 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20678675 — Surrogate Endpoint (SUR): Blood pressure
Study 18247017 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12730150 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12730150 — Surrogate Endpoint (SUR): Blood pressure
Study 11007576 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study 27777054 — Surrogate Endpoint (SUR): Bone mineral density
Study 25234311 — Surrogate Endpoint (SUR): Total kidney volume
Study 25234311 — Surrogate Endpoint (SUR): Blood pressure
Study 2067197 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 2067197 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26019245 — Surrogate Endpoint (SUR): Bone mineral density
Study 22706733 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 15477371 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 15477371 — Surrogate Endpoint (SUR): Serum testosterone
Study 30738244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28617765 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 28617765 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28617765 — Surrogate Endpoint (SUR): Blood pressure
Study 7545059 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7545059 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 2528862 — Predictive Biomarker (PRD): CLYBL mRNA
Genes: CLYBL; CLB
Study 9409357 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 12673180 — Surrogate Endpoint (SUR): Blood pressure
Study 8615502 — Safety Biomarker (SAF): Reactive oxygen species
Study 1727915 — Surrogate Endpoint (SUR): Serum calcium
Study 26780969 — Surrogate Endpoint (SUR): Sperm parameters
Study 9247511 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11082370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11082370 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 25129064 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23672463 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18242934 — Surrogate Endpoint (SUR): Blood pressure
Study 15908388 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15908388 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15908388 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30372482 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 23955660 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12780674 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 12780674 — Surrogate Endpoint (SUR): Serum creatinine
Study 26049188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22679301 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 18845781 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 3189143 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25293387 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25293387 — Surrogate Endpoint (SUR): Blood pressure
Study 30213672 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 20144173 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6401551 — Surrogate Endpoint (SUR): Blood pressure
Study 8378746 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17166340 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17166340 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17166340 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12648197 — Surrogate Endpoint (SUR): Blood pressure
Study 31473167 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17573387 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 21380980 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 21380980 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21380980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 21380980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21380980 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21380980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21380980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21380980 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18312755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18312755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18312755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9426377 — Surrogate Endpoint (SUR): Blood pressure
Study 8179648 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31116913 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 10532607 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16293341 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study 16293341 — Predictive Biomarker (PRD): NDP mRNA
Genes: NDP; EVR2
Study 3966742 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31690831 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19115650 — Surrogate Endpoint (SUR): Blood pressure
Study 9294496 — Safety Biomarker (SAF): DRD2
Study 8375125 — Surrogate Endpoint (SUR): Blood pressure
Study 30291414 — Surrogate Endpoint (SUR): Blood pressure
Study 7867240 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7867240 — Surrogate Endpoint (SUR): Blood pressure
Study 31761418 — Surrogate Endpoint (SUR): Blood pressure
Study 21922528 — Predictive Biomarker (PRD): FGF7 mRNA
Genes: FGF7; KGF
Study 18192900 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study 18192900 — Surrogate Endpoint (SUR): Blood pressure
Study 10784227 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10784227 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24675287 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24675287 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24675287 — Predictive Biomarker (PRD): Hormone receptor
Study 12047483 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7783098 — Surrogate Endpoint (SUR): Blood pressure
Study 29566379 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 22496334 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1828266 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31625535 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 26559707 — Surrogate Endpoint (SUR): Blood pressure
Study 23115402 — Surrogate Endpoint (SUR): Blood pressure
Study 11666118 — Predictive Biomarker (PRD): GSC mRNA
Genes: GSC
Study 19080399 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8688991 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8688991 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30003332 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26817718 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 26817718 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 11087205 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 7641928 — Surrogate Endpoint (SUR): Bacterial count
Study 766572 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 766572 — Surrogate Endpoint (SUR): Blood pressure
Study 27723631 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 2668407 — Surrogate Endpoint (SUR): Blood pressure
Study 2668407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2668407 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31006671 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31006671 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31006671 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16413247 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 18174038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18174038 — Surrogate Endpoint (SUR): Blood pressure
Study 18174038 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18174038 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29401239 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25439595 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27614872 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20462038 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20462038 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27935229 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 21257052 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28117133 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 28117133 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 28117133 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 27051992 — Surrogate Endpoint (SUR): Blood pressure
Study 25725933 — Surrogate Endpoint (SUR): Blood pressure
Study 23593607 — Monitoring Biomarker (MOI): HBV DNA
Study 24894077 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 20178872 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27392137 — Surrogate Endpoint (SUR): Blood pressure
Study 23361084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22584134 — Surrogate Endpoint (SUR): Blood pressure
Study 20333742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20333742 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 20333742 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 11558965 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 31490862 — Surrogate Endpoint (SUR): Blood pressure
Study 17536225 — Surrogate Endpoint (SUR): Blood pressure
Study 28235027 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28235027 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17413093 — Surrogate Endpoint (SUR): Blood pressure
Study 17413093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7914751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28245243 — Predictive Biomarker (PRD): RXFP1 mRNA
Genes: RXFP1; LGR7
Study 25409324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15058150 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7973480 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 2537699 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31984682 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28110812 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28110812 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28110812 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23719347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15332347 — Surrogate Endpoint (SUR): Blood pressure
Study 23811987 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7830861 — Safety Biomarker (SAF): Interleukin 1
Study 30391995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30391995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15385655 — Surrogate Endpoint (SUR): Serum creatinine
Study 11687509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8199696 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31173870 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25779953 — Predictive Biomarker (PRD): ROCK1 mRNA
Genes: ROCK1
Study 20081092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20081092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20081092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30669918 — Surrogate Endpoint (SUR): Bone mineral density
Study 22124101 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22124101 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9430262 — Surrogate Endpoint (SUR): Blood pressure
Study 21397769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18988075 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 11095435 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19995670 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 15517433 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31714322 — Surrogate Endpoint (SUR): Blood pressure
Study 21372756 — Surrogate Endpoint (SUR): Blood pressure
Study 21372756 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19214123 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17626759 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25391305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20861296 — Surrogate Endpoint (SUR): Forced vital capacity