TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16154181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30411802 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 26874901 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26874901 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26874901 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 26874901 — Predictive Biomarker (PRD): Hormone receptor
Study 15791442 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12472909 — Surrogate Endpoint (SUR): Blood pressure
Study 30196481 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 23748114 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 31385178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21246232 — Predictive Biomarker (PRD): GAPDH mRNA
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 8061102 — Predictive Biomarker (PRD): DNM1 mRNA
Genes: DNM1; DNM
Study 18187607 — Surrogate Endpoint (SUR): Blood pressure
Study 31315279 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 17189870 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17189870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17189870 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11472282 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25085709 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 19702706 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17481879 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 3771951 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 28965797 — Surrogate Endpoint (SUR): Blood pressure
Study 16757922 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 15093843 — Surrogate Endpoint (SUR): Blood pressure
Study 8011819 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2638182 — Surrogate Endpoint (SUR): Bacterial count
Study 26086603 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22153015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22153015 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22153015 — Surrogate Endpoint (SUR): Serum creatinine
Study 31162838 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31162838 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 31162838 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 31162838 — Predictive Biomarker (PRD): CDC20 mRNA
Genes: CDC20
Study 31162838 — Predictive Biomarker (PRD): NUF2 mRNA
Genes: NUF2; CDCA1; NUF2R
Study 31162838 — Predictive Biomarker (PRD): KIF2C mRNA
Genes: KIF2C; KNSL6
Study 31162838 — Predictive Biomarker (PRD): CENPF mRNA
Genes: CENPF
Study 31162838 — Predictive Biomarker (PRD): EMP3 mRNA
Genes: EMP3; YMP
Study 31162838 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 31162838 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 31162838 — Predictive Biomarker (PRD): FGFR4 mRNA
Genes: FGFR4; JTK2; TKF
Study 18249211 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18249211 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18249211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18249211 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18249211 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 1371197 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 18596959 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 18596959 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18596959 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 11560538 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23417658 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20878269 — Predictive Biomarker (PRD): Hormone receptor
Study 19406273 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23548855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23548855 — Surrogate Endpoint (SUR): Serum calcium
Study 8568310 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 25748698 — Surrogate Endpoint (SUR): Serum creatinine
Study 16139140 — Surrogate Endpoint (SUR): Blood pressure
Study 30770307 — Surrogate Endpoint (SUR): Serum creatinine
Study 29199012 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 10023014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27941058 — Surrogate Endpoint (SUR): Blood pressure
Study 23062214 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 19403992 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 15213620 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7684422 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 7684422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24116853 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study 11874243 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 11874243 — Surrogate Endpoint (SUR): Bone mineral density
Study 30142373 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 30142373 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30142373 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 30142373 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 16298763 — Surrogate Endpoint (SUR): Blood pressure
Study 26581687 — Surrogate Endpoint (SUR): Blood pressure
Study 2442550 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2442550 — Surrogate Endpoint (SUR): Blood pressure
Study 23615633 — Surrogate Endpoint (SUR): Serum potassium
Study 19377488 — Predictive Biomarker (PRD): SEPTIN3 mRNA
Genes: SEPTIN3; SEP3; SEPT3
Study 17125930 — Surrogate Endpoint (SUR): Blood pressure
Study 11435054 — Surrogate Endpoint (SUR): Serum potassium
Study 29067495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29067495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15998706 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23216985 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23216985 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1879086 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 31005271 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24833598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22796496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15220226 — Surrogate Endpoint (SUR): Bone mineral density
Study 17000586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17199721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17199721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16333765 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16333765 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16333765 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10531890 — Surrogate Endpoint (SUR): Blood pressure
Study 7632811 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 28687322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28687322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21490090 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 21490090 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21490090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16955282 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 2442957 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 2442957 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 22648715 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 10475293 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10475293 — Surrogate Endpoint (SUR): Blood pressure
Study 8946270 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8946270 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6126961 — Surrogate Endpoint (SUR): Blood pressure
Study 29710119 — Surrogate Endpoint (SUR): Blood pressure
Study 15850471 — Monitoring Biomarker (MOI): HBV DNA
Study 7148050 — Surrogate Endpoint (SUR): Blood pressure
Study 24553997 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20533764 — Surrogate Endpoint (SUR): Bone mineral density
Study 15867181 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8877074 — Surrogate Endpoint (SUR): Blood pressure
Study 22446296 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FasL mRNA
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 8601931 — Surrogate Endpoint (SUR): Blood pressure
Study 2004539 — Surrogate Endpoint (SUR): Blood pressure
Study 23134084 — Surrogate Endpoint (SUR): Serum sodium
Study 18311687 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18311687 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 18311687 — Safety Biomarker (SAF): BDNF
Study 1629381 — Surrogate Endpoint (SUR): Blood pressure
Study 29385952 — Predictive Biomarker (PRD): ANKS4B mRNA
Genes: ANKS4B; HARP
Study 23911756 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23911756 — Surrogate Endpoint (SUR): Blood pressure
Study 7480568 — Surrogate Endpoint (SUR): Blood pressure
Study 30732732 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23883736 — Surrogate Endpoint (SUR): Blood pressure
Study 21911633 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1687852 — Surrogate Endpoint (SUR): Blood pressure
Study 6366805 — Surrogate Endpoint (SUR): Blood pressure
Study 6366805 — Surrogate Endpoint (SUR): Serum potassium
Study 29745095 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 29745095 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29795283 — Safety Biomarker (SAF): Reactive oxygen species
Study 1854361 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6717701 — Surrogate Endpoint (SUR): Serum calcium
Study 30281882 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20090550 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 2239569 — Surrogate Endpoint (SUR): Serum creatinine
Study 31039812 — Surrogate Endpoint (SUR): Serum creatinine
Study 15043515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30901502 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 29141784 — Surrogate Endpoint (SUR): Blood pressure
Study 27342765 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 27342765 — Predictive Biomarker (PRD): MTRR mRNA
Genes: MTRR
Study 27342765 — Safety Biomarker (SAF): MTHFR
Study 21212155 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 21212155 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 21212155 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8181617 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 15926058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15926058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15926058 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15926058 — Safety Biomarker (SAF): IL-6 and IL-10
Study 18953882 — Predictive Biomarker (PRD): CDH3 mRNA
Genes: CDH3; CDHP
Study 12939228 — Surrogate Endpoint (SUR): Blood pressure
Study 19591010 — Surrogate Endpoint (SUR): Bone mineral density
Study 15463836 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 25913479 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17538878 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15031350 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 15031350 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21452293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21452293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16606972 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 9087387 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9087387 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9087387 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9087387 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26811534 — Predictive Biomarker (PRD): CELF4 mRNA
Genes: CELF4; BRUNOL4
Study 26811534 — Safety Biomarker (SAF): Cardiac troponin T
Genes: TNNT2
Study 16124442 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12204875 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 12572374 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12572374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25870084 — Surrogate Endpoint (SUR): Blood pressure
Study 24473536 — Surrogate Endpoint (SUR): Serum testosterone
Study 21885724 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21885724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15194332 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15194332 — Surrogate Endpoint (SUR): Serum creatinine
Study 9158829 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8480985 — Surrogate Endpoint (SUR): Blood pressure
Study 2434787 — Surrogate Endpoint (SUR): Blood pressure
Study 12357041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7636936 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11854763 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 9645184 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 3064775 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31451364 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 26123256 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19267255 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 15493172 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 7930702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7930702 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25716649 — Surrogate Endpoint (SUR): Blood pressure
Study 20602089 — Surrogate Endpoint (SUR): Blood pressure
Study 18845497 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18845497 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 30661474 — Surrogate Endpoint (SUR): Blood pressure
Study 27270263 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22270321 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 11543743 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 24113040 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 24113040 — Surrogate Endpoint (SUR): Blood pressure
Study 17870051 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 8776813 — Surrogate Endpoint (SUR): Serum testosterone
Study 22647517 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22647517 — Surrogate Endpoint (SUR): Blood pressure
Study 22647517 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20621734 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20621734 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 11528582 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8169385 — Safety Biomarker (SAF): Interleukin 1
Study 28623969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28623969 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 28623969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 28623969 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28623969 — Predictive Biomarker (PRD): VEGFB mRNA
Genes: VEGFB; VRF
Study 28623969 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 11070146 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11070146 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23433403 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23433403 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21875858 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15007086 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 12469051 — Safety Biomarker (SAF): MTHFR
Study 9846593 — Surrogate Endpoint (SUR): Blood pressure
Study 23652274 — Safety Biomarker (SAF): BDNF
Study 21283158 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 18957534 — Surrogate Endpoint (SUR): Blood pressure
Study 11982466 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 9619011 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9619011 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9619011 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 2502974 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 776351 — Surrogate Endpoint (SUR): Blood pressure
Study 21666744 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 19927363 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 19927363 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 8077353 — Surrogate Endpoint (SUR): Bone mineral density
Study 31977000 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 21067382 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15956965 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10432325 — Surrogate Endpoint (SUR): Serum creatinine
Study 24922198 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12568207 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12568207 — Surrogate Endpoint (SUR): Serum creatinine
Study 12568207 — Surrogate Endpoint (SUR): Blood pressure
Study 29777144 — Safety Biomarker (SAF): IL-6 and IL-10
Study 18814836 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 12732586 — Surrogate Endpoint (SUR): Blood pressure
Study 10821360 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29447770 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26817879 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17651416 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 16329022 — Surrogate Endpoint (SUR): Blood pressure
Study 11917284 — Surrogate Endpoint (SUR): Blood pressure
Study 31880586 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 29231317 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 22942402 — Surrogate Endpoint (SUR): Blood pressure
Study 21485668 — Surrogate Endpoint (SUR): Blood pressure
Study 15202297 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11552906 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9559415 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7513981 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 17952589 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17952589 — Predictive Biomarker (PRD): Hormone receptor
Study 30759235 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30759235 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30759235 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20047560 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20047560 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23078984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10453833 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 10453833 — Safety Biomarker (SAF): Reactive oxygen species