TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28295959 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28295959 — Surrogate Endpoint (SUR): Blood pressure
Study 21266519 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 19846022 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17298707 — Predictive Biomarker (PRD): SYN1 mRNA
Genes: SYN1
Study 17298707 — Surrogate Endpoint (SUR): Bone mineral density
Study 29031393 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29031393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22056152 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28214948 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28214948 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 20441720 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11755936 — Surrogate Endpoint (SUR): Blood pressure
Study 30137250 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21194181 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 21194181 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 21194181 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 21194181 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19929258 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21610662 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 10335039 — Surrogate Endpoint (SUR): Bone mineral density
Study 22580944 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 11796357 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7658946 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 2698943 — Surrogate Endpoint (SUR): Blood pressure
Study 184912 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 30843046 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30939487 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 20805005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16525137 — Monitoring Biomarker (MOI): HBV DNA
Study 31633760 — Surrogate Endpoint (SUR): Blood pressure
Study 16342344 — Surrogate Endpoint (SUR): Blood pressure
Study 15259390 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 25780881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20855072 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20855072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20855072 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20855072 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9199943 — Surrogate Endpoint (SUR): Blood pressure
Study 4005127 — Surrogate Endpoint (SUR): Blood pressure
Study 18178372 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 31101018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26656773 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20543737 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 1283730 — Surrogate Endpoint (SUR): Serum creatinine
Study 1283730 — Surrogate Endpoint (SUR): Serum potassium
Study 1283730 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30043192 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 22964975 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22964975 — Surrogate Endpoint (SUR): Blood pressure
Study 24283160 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24283160 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23608562 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 23608562 — Predictive Biomarker (PRD): POLM mRNA
Genes: POLM; polmu
Study 19607949 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 19607949 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 19607949 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17885853 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12133499 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study 31782181 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study 31782181 — Predictive Biomarker (PRD): CNTNAP2 mRNA
Genes: CNTNAP2; CASPR2; KIAA0868
Study 19362318 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25417401 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25417401 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25417401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25417401 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23176374 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23176374 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 1686811 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 31668850 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31668850 — Predictive Biomarker (PRD): Hormone receptor
Study 22322821 — Surrogate Endpoint (SUR): Blood pressure
Study 22322821 — Surrogate Endpoint (SUR): Serum sodium
Study 9817161 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9817161 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31282402 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 23519639 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19406908 — Safety Biomarker (SAF): Hyaluronic acid
Study 16772320 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16772320 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9594153 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 3993552 — Surrogate Endpoint (SUR): Serum potassium
Study 22872647 — Monitoring Biomarker (MOI): HBV DNA
Study 20309947 — Surrogate Endpoint (SUR): Bacterial count
Study 1353507 — Surrogate Endpoint (SUR): Blood pressure
Study 1353507 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6426618 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 30894212 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 19157710 — Surrogate Endpoint (SUR): Blood pressure
Study 11868855 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8198023 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8198023 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27194403 — Surrogate Endpoint (SUR): Blood pressure
Study 10724638 — Surrogate Endpoint (SUR): Serum potassium
Study 10724638 — Surrogate Endpoint (SUR): Blood pressure
Study 28577665 — Surrogate Endpoint (SUR): Blood pressure
Study 23450444 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23450444 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31054263 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11007579 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11007579 — Surrogate Endpoint (SUR): Blood pressure
Study 9377070 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 3530645 — Surrogate Endpoint (SUR): Blood pressure
Study 26849119 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26849119 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3073655 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28133766 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 18689384 — Surrogate Endpoint (SUR): Bone mineral density
Study 30270019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30270019 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30270019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22071024 — Surrogate Endpoint (SUR): Bone mineral density
Study 17382734 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31707825 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26166655 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 17133475 — Monitoring Biomarker (MOI): HBV DNA
Study 10720032 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 30783215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24400998 — Predictive Biomarker (PRD): GCG mRNA
Genes: GCG
Study 24400998 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20952270 — Surrogate Endpoint (SUR): Serum calcium
Study 11288822 — Surrogate Endpoint (SUR): Blood pressure
Study 11288822 — Surrogate Endpoint (SUR): Serum creatinine
Study 26706833 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 26706833 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26706833 — Predictive Biomarker (PRD): Hormone receptor
Study 26706833 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19855955 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25520426 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23088178 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 18991076 — Surrogate Endpoint (SUR): Blood pressure
Study 18991076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18991076 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11938827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11938827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11938827 — Safety Biomarker (SAF): IL-6 and IL-10
Study 29142243 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20518178 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19294863 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 1930916 — Surrogate Endpoint (SUR): Blood pressure
Study 6890761 — Surrogate Endpoint (SUR): Plasma ammonia
Study 31623223 — Surrogate Endpoint (SUR): Blood pressure
Study 28441856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28441856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28441856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21777884 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 19622627 — Surrogate Endpoint (SUR): Bone mineral density
Study 16700848 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2083195 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2083195 — Predictive Biomarker (PRD): FER mRNA
Genes: FER; TYK3
Study 2083195 — Surrogate Endpoint (SUR): Blood pressure
Study 30678029 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25123755 — Surrogate Endpoint (SUR): Serum creatinine
Study 22190065 — Surrogate Endpoint (SUR): Serum uric acid
Study 11994341 — Surrogate Endpoint (SUR): Bone mineral density
Study 25424464 — Surrogate Endpoint (SUR): Blood pressure
Study 23029716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31781682 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31781682 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17113170 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15066944 — Surrogate Endpoint (SUR): Blood pressure
Study 10921031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10921031 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 10921031 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10921031 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25732157 — Surrogate Endpoint (SUR): Serum testosterone
Study 17619911 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29382797 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 29382797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29382797 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 25049001 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 21909820 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16380670 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 7037502 — Surrogate Endpoint (SUR): Blood pressure
Study 21299408 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 3312789 — Surrogate Endpoint (SUR): Serum creatinine
Study 31425480 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31394768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31394768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31394768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31394768 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28607336 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 18513463 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18513463 — Surrogate Endpoint (SUR): Serum uric acid
Study 16263768 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 9720838 — Surrogate Endpoint (SUR): Sperm parameters
Study 9720838 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 2902379 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31012819 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 10944136 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8100611 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2880655 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29479645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23535509 — Surrogate Endpoint (SUR): Bone mineral density
Study 10978402 — Surrogate Endpoint (SUR): Blood pressure
Study 21029662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21029662 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 21029662 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21029662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21029662 — Surrogate Endpoint (SUR): Bone mineral density
Study 8934215 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8934215 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27471803 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 14578611 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14578611 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31765046 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 15376499 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 11576376 — Surrogate Endpoint (SUR): Bone mineral density
Study 11576376 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26137916 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11410122 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 9390695 — Predictive Biomarker (PRD): LGSN mRNA
Genes: LGSN; GLULD1; LGS
Study 7829623 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23051740 — Surrogate Endpoint (SUR): Blood pressure
Study 21887284 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 21887284 — Predictive Biomarker (PRD): MMP12 mRNA
Genes: MMP12; HME
Study 12846708 — Surrogate Endpoint (SUR): Blood pressure
Study 1826285 — Surrogate Endpoint (SUR): Blood pressure
Study 9115060 — Surrogate Endpoint (SUR): Serum creatinine
Study 1490503 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 27021606 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 19952781 — Surrogate Endpoint (SUR): Blood pressure
Study 26567123 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26391130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26391130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26391130 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26391130 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20571360 — Surrogate Endpoint (SUR): Blood pressure
Study 16614408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 24621069 — Predictive Biomarker (PRD): RTN1 mRNA
Genes: RTN1; NSP
Study 1720012 — Surrogate Endpoint (SUR): Serum calcium
Study 16439468 — Predictive Biomarker (PRD): TLR5
Genes: TIL3; FLJ10052; MGC126430; MGC126431
Study 6439286 — Surrogate Endpoint (SUR): Blood pressure
Study 6439286 — Surrogate Endpoint (SUR): Serum creatinine
Study 31714453 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20460227 — Surrogate Endpoint (SUR): Bone mineral density
Study 31697873 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 9368551 — Surrogate Endpoint (SUR): Blood pressure
Study 22827512 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15619390 — Surrogate Endpoint (SUR): Blood pressure
Study 11871954 — Surrogate Endpoint (SUR): Blood pressure
Study 10190266 — Safety Biomarker (SAF): MTHFR
Study 22340428 — Predictive Biomarker (PRD): GPR119 mRNA
Genes: GPR119
Study 20090397 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31916571 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 15203290 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9568752 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3229340 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3229340 — Surrogate Endpoint (SUR): Blood pressure
Study 29514224 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 24691410 — Surrogate Endpoint (SUR): Blood pressure
Study 20371584 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 20371584 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8743497 — Surrogate Endpoint (SUR): Blood pressure
Study 30894658 — Surrogate Endpoint (SUR): Blood pressure
Study 28835586 — Surrogate Endpoint (SUR): Serum creatinine
Study 24362944 — Surrogate Endpoint (SUR): Serum creatinine
Study 19386059 — Surrogate Endpoint (SUR): Blood pressure
Study 4348345 — Surrogate Endpoint (SUR): Blood pressure
Study 4348345 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 27633880 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 27633880 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 11281614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11281614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11281614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7994784 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 15037882 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 10910003 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 23929260 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 8387084 — Surrogate Endpoint (SUR): Blood pressure
Study 30446405 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 27118620 — Surrogate Endpoint (SUR): Blood pressure
Study 24572702 — Surrogate Endpoint (SUR): Blood pressure
Study 11061578 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8393389 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28947569 — Surrogate Endpoint (SUR): Blood pressure
Study 12477620 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12477620 — Surrogate Endpoint (SUR): Blood pressure
Study 8963482 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 31362531 — Surrogate Endpoint (SUR): Blood pressure
Study 30830724 — Surrogate Endpoint (SUR): Blood pressure
Study 26469986 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21864886 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 21864886 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19645779 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9141914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9141914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7944696 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24144615 — Predictive Biomarker (PRD): ST8SIA4 mRNA
Genes: ST8SIA4; PST; PST1; SIAT8D