TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27161611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23106871 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17284626 — Surrogate Endpoint (SUR): Bone mineral density
Study 11216931 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30297663 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18375093 — Surrogate Endpoint (SUR): Blood pressure
Study 10997878 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 6144625 — Surrogate Endpoint (SUR): Serum sodium
Study 19864958 — Surrogate Endpoint (SUR): Blood pressure
Study 6377568 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 23228403 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27084728 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21948942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11932879 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 9474925 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 28848126 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16905810 — Safety Biomarker (SAF): Hyaluronic acid
Study 7893583 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17906871 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 17906871 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17906871 — Surrogate Endpoint (SUR): Blood pressure
Study 16827862 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 16827862 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10638606 — Surrogate Endpoint (SUR): Blood pressure
Study 10638606 — Surrogate Endpoint (SUR): Serum creatinine
Study 24560584 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19281535 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 19281535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19281535 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12271103 — Surrogate Endpoint (SUR): Blood pressure
Study 9814627 — Surrogate Endpoint (SUR): Serum creatinine
Study 9814627 — Surrogate Endpoint (SUR): Blood pressure
Study 17356091 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11257264 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 11257264 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7981459 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24706191 — Surrogate Endpoint (SUR): Blood pressure
Study 21287904 — Surrogate Endpoint (SUR): Blood pressure
Study 21287904 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31246097 — Surrogate Endpoint (SUR): Blood pressure
Study 27856088 — Surrogate Endpoint (SUR): Total kidney volume
Study 24450252 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12587621 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 12587621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23478699 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15944095 — Surrogate Endpoint (SUR): Blood pressure
Study 29307310 — Surrogate Endpoint (SUR): Blood pressure
Study 25225951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25225951 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17395053 — Surrogate Endpoint (SUR): Serum creatinine
Study 17395053 — Surrogate Endpoint (SUR): Serum sodium
Study 11758798 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11758798 — Surrogate Endpoint (SUR): Blood pressure
Study 9504571 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 9504571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9504571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30917927 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 117953 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 27931291 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19951217 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 11953878 — Surrogate Endpoint (SUR): Serum calcium
Study 9797079 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 9797079 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9797079 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 9797079 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study 10436979 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10436979 — Monitoring Biomarker (MOI): HBV DNA
Study 27494777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27494777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19962288 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 10998316 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 10998316 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 10998316 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8869096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25940250 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21615492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1405361 — Surrogate Endpoint (SUR): Blood pressure
Study 24516103 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24516103 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21679921 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 12016800 — Surrogate Endpoint (SUR): Serum potassium
Study 17267793 — Surrogate Endpoint (SUR): Blood pressure
Study 28168555 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17364587 — Surrogate Endpoint (SUR): Blood pressure
Study 15164513 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 8045844 — Surrogate Endpoint (SUR): Blood pressure
Study 12946074 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 8383058 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29109117 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 29109117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 29109117 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29109117 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25574960 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8729141 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8729141 — Surrogate Endpoint (SUR): Blood pressure
Study 6211228 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12536287 — Surrogate Endpoint (SUR): Serum uric acid
Study 26364686 — Surrogate Endpoint (SUR): Bone mineral density
Study 10911654 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 10911654 — Surrogate Endpoint (SUR): Serum sodium
Study 10911654 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30374788 — Surrogate Endpoint (SUR): Bone mineral density
Study 20097931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26176848 — Surrogate Endpoint (SUR): Serum creatinine
Study 10952796 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 4006253 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29635145 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29635145 — Predictive Biomarker (PRD): Hormone receptor
Study 15987916 — Monitoring Biomarker (MOI): HBV DNA
Study 2389686 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27623523 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 17426195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10871565 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1610632 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30140094 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 26340471 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23199430 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31915040 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2216613 — Surrogate Endpoint (SUR): Serum potassium
Study 27355500 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 31146717 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31146717 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 31146717 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31146717 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 19407810 — Surrogate Endpoint (SUR): Blood pressure
Study 14593367 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 14593367 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 14593367 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30531305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30531305 — Surrogate Endpoint (SUR): Bone mineral density
Study 30246286 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 30246286 — Surrogate Endpoint (SUR): Blood pressure
Study 30246286 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11981149 — Surrogate Endpoint (SUR): Blood pressure
Study 30927953 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 25966108 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25966108 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16424345 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2880530 — Surrogate Endpoint (SUR): Blood pressure
Study 2675812 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29190851 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 29190851 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29190851 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15142026 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 9263613 — Surrogate Endpoint (SUR): Bone mineral density
Study 25460174 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25460174 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 23414697 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 17110590 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 14764132 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 14764132 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14764132 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11762555 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 11762555 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 11762555 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11762555 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7547097 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7547097 — Surrogate Endpoint (SUR): Blood pressure
Study 31296588 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 31296588 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 25266426 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22312103 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 22312103 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16287370 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16287370 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 8965300 — Surrogate Endpoint (SUR): Blood pressure
Study 1303534 — Surrogate Endpoint (SUR): Blood pressure
Study 25480344 — Surrogate Endpoint (SUR): Serum potassium
Study 19926964 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18432176 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 14578137 — Safety Biomarker (SAF): Reactive oxygen species
Study 8938652 — Surrogate Endpoint (SUR): Blood pressure
Study 18984888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15894946 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7574741 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2153478 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28112528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22904118 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21272188 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8393795 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8393795 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8393795 — Surrogate Endpoint (SUR): Blood pressure
Study 23483627 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 20452283 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 18775668 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 9781723 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9781723 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9781723 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8143426 — Surrogate Endpoint (SUR): Blood pressure
Study 31871950 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28483174 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 28483174 — Predictive Biomarker (PRD): SKAP2 mRNA
Genes: SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R
Study 28483174 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 9107560 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1601837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1601837 — Safety Biomarker (SAF): Interleukin 1
Study 28065235 — Surrogate Endpoint (SUR): Serum potassium
Study 2743965 — Surrogate Endpoint (SUR): Blood pressure
Study 30848025 — Surrogate Endpoint (SUR): Blood pressure
Study 28029066 — Surrogate Endpoint (SUR): Blood pressure
Study 26302024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24250224 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24250224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24250224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15728061 — Surrogate Endpoint (SUR): Blood pressure
Study 22972364 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7982129 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28252160 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 28169881 — Surrogate Endpoint (SUR): Blood pressure
Study 9240689 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 14960504 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14960504 — Surrogate Endpoint (SUR): Serum creatinine
Study 14960504 — Surrogate Endpoint (SUR): Blood pressure
Study 7866912 — Surrogate Endpoint (SUR): Serum calcium
Study 7866912 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 7866912 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 31600006 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 29246257 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 26667662 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 15298560 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15298560 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 15298560 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11358645 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11358645 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10225747 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27888990 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 27888990 — Surrogate Endpoint (SUR): Serum creatinine
Study 24948549 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 21092089 — Surrogate Endpoint (SUR): Blood pressure
Study 16340193 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 16340193 — Predictive Biomarker (PRD): RRM2 mRNA
Genes: RRM2; RR2
Study 22210087 — Predictive Biomarker (PRD): Hormone receptor
Study 20155842 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 20155842 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 18716168 — Surrogate Endpoint (SUR): Blood pressure
Study 18716168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23994107 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 15361886 — Surrogate Endpoint (SUR): Blood pressure
Study 11524054 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 11524054 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18603377 — Surrogate Endpoint (SUR): Blood pressure
Study 11594641 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 9641613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8039850 — Surrogate Endpoint (SUR): Blood pressure
Study 8039850 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8039850 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24430001 — Surrogate Endpoint (SUR): Blood pressure
Study 16079444 — Surrogate Endpoint (SUR): Blood pressure
Study 30123047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30123047 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30123047 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30123047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17356942 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31887168 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31887168 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27363929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27363929 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29181658 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25638248 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 15154115 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 15154115 — Surrogate Endpoint (SUR): Serum creatinine
Study 21455716 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 21455716 — Surrogate Endpoint (SUR): Bone mineral density
Study 30961947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30961947 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 30961947 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30961947 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30961947 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 30961947 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9714487 — Monitoring Biomarker (MOI): Procalcitonin
Study 9714487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24711067 — Surrogate Endpoint (SUR): Blood pressure
Study 7836734 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24675911 — Surrogate Endpoint (SUR): Blood pressure
Study 29457538 — Surrogate Endpoint (SUR): Blood pressure
Study 25319187 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25319187 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20403637 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 2187002 — Predictive Biomarker (PRD): DIAPH2 mRNA
Genes: DIAPH2; DIA
Study 30500981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28972083 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11766084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18443762 — Surrogate Endpoint (SUR): Blood pressure
Study 8782754 — Surrogate Endpoint (SUR): Blood pressure
Study 1352363 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6424580 — Surrogate Endpoint (SUR): Blood pressure
Study 30173303 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B