TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22418272 — Surrogate Endpoint (SUR): Blood pressure
Study 1927586 — Surrogate Endpoint (SUR): Blood pressure
Study 17143197 — Surrogate Endpoint (SUR): Blood pressure
Study 1948128 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 29334906 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10837185 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 2947723 — Monitoring Biomarker (MOI): HBV DNA
Study 31243641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30042488 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 30042488 — Surrogate Endpoint (SUR): Blood pressure
Study 24903630 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20203367 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 7503048 — Surrogate Endpoint (SUR): Blood pressure
Study 30408717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30408717 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30408717 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30408717 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22207490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20100959 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20100959 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10972455 — Surrogate Endpoint (SUR): Blood pressure
Study 21143864 — Surrogate Endpoint (SUR): Blood pressure
Study 9612217 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26874557 — Surrogate Endpoint (SUR): Blood pressure
Study 22468627 — Surrogate Endpoint (SUR): Blood pressure
Study 2499178 — Predictive Biomarker (PRD): RPIA mRNA
Genes: RPIA; RPI
Study 26269566 — Predictive Biomarker (PRD): CPT1A mRNA
Genes: CPT1A; CPT1
Study 26269566 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 26269566 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 17572834 — Surrogate Endpoint (SUR): Bone mineral density
Study 14747227 — Surrogate Endpoint (SUR): Blood pressure
Study 8142663 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31093954 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 28777984 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 24078554 — Surrogate Endpoint (SUR): Blood pressure
Study 19673614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19673614 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16275011 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10619929 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10619929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8616766 — Predictive Biomarker (PRD): CHAD mRNA
Genes: CHAD; SLRR4A
Study 10509552 — Surrogate Endpoint (SUR): Blood pressure
Study 7815656 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31761539 — Predictive Biomarker (PRD): MPV17L2 mRNA
Genes: MPV17L2; FKSG24
Study 31761539 — Predictive Biomarker (PRD): PIF1 mRNA
Genes: PIF1; C15orf20
Study 31761539 — Predictive Biomarker (PRD): LPIN1 mRNA
Genes: LPIN1; KIAA0188
Study 31761539 — Predictive Biomarker (PRD): DCTN3 mRNA
Genes: DCTN3; DCTN22
Study 31761539 — Predictive Biomarker (PRD): DERA mRNA
Genes: DERA; CGI-26
Study 31761539 — Predictive Biomarker (PRD): ATP7B mRNA
Genes: ATP7B; PWD; WC1; WND
Study 31761539 — Predictive Biomarker (PRD): NEK5 mRNA
Genes: NEK5
Study 31761539 — Predictive Biomarker (PRD): HVCN1 mRNA
Genes: HVCN1; VSOP; UNQ578/PRO1140
Study 31761539 — Predictive Biomarker (PRD): MARK2 mRNA
Genes: MARK2; EMK1
Study 22906808 — Surrogate Endpoint (SUR): Blood pressure
Study 30672192 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10634364 — Surrogate Endpoint (SUR): Serum testosterone
Study 2906699 — Surrogate Endpoint (SUR): Blood pressure
Study 28641703 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8862952 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27228432 — Surrogate Endpoint (SUR): Blood pressure
Study 15711037 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15711037 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 28553094 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19687343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19687343 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26580234 — Surrogate Endpoint (SUR): Bone mineral density
Study 16253100 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 12037693 — Surrogate Endpoint (SUR): Blood pressure
Study 12037693 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10208561 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30429410 — Predictive Biomarker (PRD): ANGPTL8 mRNA
Genes: ANGPTL8; C19orf80; RIFL; UNQ599/PRO1185
Study 27893326 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 27893326 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study 25778467 — Predictive Biomarker (PRD): ACSL1 mRNA
Genes: ACSL1; FACL1; FACL2; LACS; LACS1; LACS2
Study 25778467 — Predictive Biomarker (PRD): XPO4 mRNA
Genes: XPO4; KIAA1721
Study 25778467 — Predictive Biomarker (PRD): TAS1R3 mRNA
Genes: TAS1R3; T1R3; TR3
Study 25778467 — Predictive Biomarker (PRD): LCA5 mRNA
Genes: LCA5; C6orf152
Study 25778467 — Predictive Biomarker (PRD): DNAH5 mRNA
Genes: DNAH5; DNAHC5; HL1; KIAA1603
Study 25778467 — Predictive Biomarker (PRD): PTPRG mRNA
Genes: PTPRG; PTPG
Study 25778467 — Predictive Biomarker (PRD): MAGI1 mRNA
Genes: MAGI1; AIP3; BAIAP1; BAP1; TNRC19
Study 25778467 — Predictive Biomarker (PRD): STRADA mRNA
Genes: STRADA; LYK5; STRAD
Study 25778467 — Predictive Biomarker (PRD): AKAP12 mRNA
Genes: AKAP12; AKAP250
Study 25778467 — Predictive Biomarker (PRD): ARFGEF2 mRNA
Genes: ARFGEF2; ARFGEP2; BIG2
Study 23337018 — Surrogate Endpoint (SUR): Serum testosterone
Study 19619442 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 16249701 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12072676 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30208421 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18633177 — Surrogate Endpoint (SUR): Blood pressure
Study 23415779 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19154960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7895895 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3318450 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25591431 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20722026 — Surrogate Endpoint (SUR): Blood pressure
Study 18685062 — Surrogate Endpoint (SUR): Blood pressure
Study 30744529 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 27034176 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 8576661 — Surrogate Endpoint (SUR): Blood pressure
Study 21458191 — Predictive Biomarker (PRD): KIF6 mRNA
Genes: KIF6; C6orf102
Study 21458191 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3436153 — Surrogate Endpoint (SUR): Serum sodium
Study 16563324 — Surrogate Endpoint (SUR): Blood pressure
Study 23341572 — Safety Biomarker (SAF): HSD17B1 mRNA
Genes: HSD17B1; E17KSR; EDH17B1; EDH17B2; EDHB17; SDR28C1
Study 23341572 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 23341572 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23341572 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 19302581 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 9814458 — Surrogate Endpoint (SUR): Serum calcium
Study 28660719 — Surrogate Endpoint (SUR): Blood pressure
Study 15126990 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28389125 — Surrogate Endpoint (SUR): Blood pressure
Study 25657051 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 31626100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31626100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26142266 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22989378 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 22989378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22989378 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20571252 — Safety Biomarker (SAF): MTHFR
Study 8828539 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 24972963 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 9383690 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 2452920 — Surrogate Endpoint (SUR): Blood pressure
Study 21835294 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16707747 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 14630985 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9216973 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9216973 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9216973 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7967419 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2441167 — Surrogate Endpoint (SUR): Blood pressure
Study 25914474 — Monitoring Biomarker (MOI): HBV DNA
Study 23881958 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12962775 — Surrogate Endpoint (SUR): Blood pressure
Study 7966077 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31185379 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 26621634 — Surrogate Endpoint (SUR): Blood pressure
Study 17015784 — Surrogate Endpoint (SUR): Blood pressure
Study 11035136 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11035136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11035136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31600343 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27484880 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 27453302 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 19897678 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19897678 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7674841 — Monitoring Biomarker (MOI): HBV DNA
Study 21107435 — Surrogate Endpoint (SUR): Blood pressure
Study 31684758 — Surrogate Endpoint (SUR): Blood pressure
Study 20799296 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20799296 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9425911 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3049116 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 21636116 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 11268375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3952172 — Surrogate Endpoint (SUR): Blood pressure
Study 20345708 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18544975 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study 18544975 — Surrogate Endpoint (SUR): Blood pressure
Study 8739857 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31711168 — Surrogate Endpoint (SUR): Blood pressure
Study 19616166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17196453 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15272394 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 18389332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18389332 — Surrogate Endpoint (SUR): Blood pressure
Study 18389332 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18389332 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15358643 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3310529 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 24300152 — Surrogate Endpoint (SUR): Bone mineral density
Study 18421460 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8610922 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28816242 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 12186794 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9933261 — Surrogate Endpoint (SUR): Blood pressure
Study 7748048 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7748048 — Surrogate Endpoint (SUR): Blood pressure
Study 24250318 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22566115 — Surrogate Endpoint (SUR): Blood pressure
Study 18576354 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 18576354 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18576354 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 31646981 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 30737098 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23245705 — Surrogate Endpoint (SUR): Blood pressure
Study 14714242 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2521934 — Surrogate Endpoint (SUR): Blood pressure
Study 29025830 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 25927504 — Surrogate Endpoint (SUR): Bone mineral density
Study 19326811 — Surrogate Endpoint (SUR): Blood pressure
Study 24621971 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 21149427 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8911338 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25695618 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 25695618 — Predictive Biomarker (PRD): CSMD1 mRNA
Genes: CSMD1; KIAA1890; UNQ5952/PRO19863
Study 22051162 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 9809846 — Predictive Biomarker (PRD): ALPK1 mRNA
Genes: ALPK1; KIAA1527; LAK
Study 25703086 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24319685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24319685 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 24319685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20965319 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30036596 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26871954 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 7836027 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 29882318 — Surrogate Endpoint (SUR): Blood pressure
Study 18394162 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17572317 — Surrogate Endpoint (SUR): Blood pressure
Study 11432888 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17904817 — Surrogate Endpoint (SUR): Blood pressure
Study 2856702 — Surrogate Endpoint (SUR): Blood pressure
Study 30261306 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22546132 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 22546132 — Safety Biomarker (SAF): Interleukin 1
Study 22546132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16382061 — Predictive Biomarker (PRD): Hormone receptor
Study 11206587 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1517788 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24074777 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18174880 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18174880 — Surrogate Endpoint (SUR): Blood pressure
Study 2939217 — Surrogate Endpoint (SUR): Blood pressure
Study 18369631 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10643842 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23406256 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 21211651 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8568016 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 30587323 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12954158 — Surrogate Endpoint (SUR): Blood pressure
Study 30346660 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 28886083 — Surrogate Endpoint (SUR): Blood pressure
Study 16311436 — Surrogate Endpoint (SUR): Bone mineral density
Study 27993418 — Surrogate Endpoint (SUR): Blood pressure
Study 18329818 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 1697373 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1697373 — Surrogate Endpoint (SUR): Blood pressure
Study 25022108 — Surrogate Endpoint (SUR): Blood pressure
Study 22949599 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 20058615 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17584555 — Surrogate Endpoint (SUR): Blood pressure
Study 15363008 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11530028 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23233651 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10572606 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 30403976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30403976 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24690513 — Surrogate Endpoint (SUR): Blood pressure
Study 2021151 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2021151 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8397246 — Surrogate Endpoint (SUR): Blood pressure
Study 21221681 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 4357222 — Surrogate Endpoint (SUR): Blood pressure
Study 17203621 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 25190072 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 21597387 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19812066 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 19812066 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19812066 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 31996422 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31996422 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22957727 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 20496728 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 20496728 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17186726 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 17186726 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17186726 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29270001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29270001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25668196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24667750 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11280344 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 27317162 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27317162 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27317162 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19036981 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 15696567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15696567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1991653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1991653 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6140837 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31296293 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17638395 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17454966 — Surrogate Endpoint (SUR): Blood pressure
Study 29617391 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 24274358 — Safety Biomarker (SAF): Hyaluronic acid
Study 24274358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10907666 — Safety Biomarker (SAF): DRD3
Study 6545038 — Surrogate Endpoint (SUR): Blood pressure
Study 24721435 — Surrogate Endpoint (SUR): Blood pressure
Study 21700548 — Predictive Biomarker (PRD): HR mRNA
Genes: HR