TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21771722 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 16371604 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 2225558 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 25762165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15270367 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15270367 — Surrogate Endpoint (SUR): Blood pressure
Study 27444039 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 18523316 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18523316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12849766 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 9509074 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 21060995 — Surrogate Endpoint (SUR): Blood pressure
Study 11546660 — Predictive Biomarker (PRD): BLK mRNA
Genes: BLK
Study 820708 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 820708 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 820708 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 25231186 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25231186 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25231186 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20815272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2206774 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28035542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22382664 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20170790 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15770966 — Surrogate Endpoint (SUR): Serum creatinine
Study 9618736 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 28430947 — Surrogate Endpoint (SUR): Blood pressure
Study 11870140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11870140 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 11870140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11870140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9871425 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 2571860 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 31434149 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25355211 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 10201739 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 10201739 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 10201739 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10201739 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21912270 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 17342036 — Surrogate Endpoint (SUR): Blood pressure
Study 9620360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9620360 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9620360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29360600 — Surrogate Endpoint (SUR): Blood pressure
Study 9817265 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 765528 — Surrogate Endpoint (SUR): Blood pressure
Study 25452437 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 19854376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19854376 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8597883 — Safety Biomarker (SAF): Interleukin 1
Study 8597883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30885233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30885233 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3117399 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 28739443 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24978844 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 22822623 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11022875 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18215618 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 1592575 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 6375274 — Surrogate Endpoint (SUR): Blood pressure
Study 23012688 — Surrogate Endpoint (SUR): Blood pressure
Study 22340283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12105140 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1341875 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29378016 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 27225949 — Surrogate Endpoint (SUR): Blood pressure
Study 20014878 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17589629 — Surrogate Endpoint (SUR): Blood pressure
Study 15805347 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12151908 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1669490 — Surrogate Endpoint (SUR): Blood pressure
Study 22087585 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22087585 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17367312 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17367312 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28455199 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17133564 — Surrogate Endpoint (SUR): Serum creatinine
Study 11050639 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 22200728 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22200728 — Surrogate Endpoint (SUR): Blood pressure
Study 20659956 — Safety Biomarker (SAF): BDNF
Study 20659956 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 1790542 — Surrogate Endpoint (SUR): Blood pressure
Study 25784719 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19299322 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16886840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16886840 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16886840 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 8205301 — Surrogate Endpoint (SUR): Blood pressure
Study 8205301 — Surrogate Endpoint (SUR): Serum creatinine
Study 21252253 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21252253 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16936102 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 12805326 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22443183 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17911711 — Surrogate Endpoint (SUR): Blood pressure
Study 9407423 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9407423 — Surrogate Endpoint (SUR): Blood pressure
Study 2894890 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2894890 — Surrogate Endpoint (SUR): Blood pressure
Study 28705697 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25832289 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18297254 — Surrogate Endpoint (SUR): Blood pressure
Study 12681027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12681027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24154666 — Predictive Biomarker (PRD): RGS2 mRNA
Genes: RGS2; G0S8; GIG31
Study 24154666 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 24154666 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 24154666 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 16983120 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1569652 — Surrogate Endpoint (SUR): Urinary oxalate
Study 30864748 — Surrogate Endpoint (SUR): Blood pressure
Study 18478213 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 10369259 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study 31020002 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 17112529 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17112529 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26214142 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 20357366 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 18065789 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 16107989 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16107989 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 31995406 — Surrogate Endpoint (SUR): Blood pressure
Study 25552575 — Surrogate Endpoint (SUR): Blood pressure
Study 22872734 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27057659 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 20385971 — Surrogate Endpoint (SUR): Blood pressure
Study 18359175 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16093400 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16093400 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19622121 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 30187284 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 28853492 — Predictive Biomarker (PRD): TACR1 mRNA
Genes: TACR1; NK1R; TAC1R
Study 22129066 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 11940726 — Surrogate Endpoint (SUR): Serum calcium
Study 11940726 — Surrogate Endpoint (SUR): Bone mineral density
Study 8880611 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21541727 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 21541727 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 15642722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10979918 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 2883273 — Surrogate Endpoint (SUR): Blood pressure
Study 29514344 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 28636208 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 24170762 — Surrogate Endpoint (SUR): Blood pressure
Study 21939839 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21939839 — Surrogate Endpoint (SUR): Blood pressure
Study 3544755 — Surrogate Endpoint (SUR): Blood pressure
Study 26608839 — Safety Biomarker (SAF): Reactive oxygen species
Study 8347333 — Surrogate Endpoint (SUR): Blood pressure
Study 26501147 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 26501147 — Surrogate Endpoint (SUR): Blood pressure
Study 19176401 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 19176401 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17089021 — Predictive Biomarker (PRD): SEPHS1 mRNA
Genes: SEPHS1; SELD; SPS; SPS1
Study 16961161 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19752769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10223928 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28625505 — Surrogate Endpoint (SUR): Blood pressure
Study 19816505 — Surrogate Endpoint (SUR): Blood pressure
Study 15630900 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 11378833 — Surrogate Endpoint (SUR): Blood pressure
Study 30868829 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 20462978 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 8869799 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23561959 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16948354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16948354 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10920334 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31092695 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29214348 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 30739626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12751378 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3087293 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 29022746 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 29022746 — Surrogate Endpoint (SUR): Blood pressure
Study 24890738 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11240120 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 2895596 — Surrogate Endpoint (SUR): Blood pressure
Study 22562960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22562960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22562960 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 4039775 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 31557306 — Predictive Biomarker (PRD): BBS9 mRNA
Genes: BBS9; PTHB1
Study 31557306 — Predictive Biomarker (PRD): KATNIP mRNA
Genes: KATNIP; KIAA0556
Study 31557306 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20138102 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28558941 — Safety Biomarker (SAF): DRD2
Study 23406721 — Surrogate Endpoint (SUR): Blood pressure
Study 17556788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9549834 — Surrogate Endpoint (SUR): Blood pressure
Study 7528449 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3382060 — Predictive Biomarker (PRD): MTRR mRNA
Genes: MTRR
Study 24029861 — Predictive Biomarker (PRD): CYP27A1 mRNA
Genes: CYP27A1; CYP27
Study 24029861 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 15975326 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9250456 — Surrogate Endpoint (SUR): Blood pressure
Study 11344179 — Surrogate Endpoint (SUR): Bone mineral density
Study 7859805 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 23442899 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11330886 — Surrogate Endpoint (SUR): Blood pressure
Study 9217621 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9217621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9217621 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26848262 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 29198193 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24021044 — Monitoring Biomarker (MOI): Procalcitonin
Study 16794491 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31582304 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17629139 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 17573321 — Surrogate Endpoint (SUR): Bone mineral density
Study 8790074 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8790074 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26312614 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26312614 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 26312614 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 20649501 — Surrogate Endpoint (SUR): Blood pressure
Study 30874292 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 28701300 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21257979 — Surrogate Endpoint (SUR): Blood pressure
Study 15541915 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15541915 — Surrogate Endpoint (SUR): Serum potassium
Study 21224837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9141231 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31386610 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31386610 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23279307 — Surrogate Endpoint (SUR): Blood pressure
Study 23279307 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18492834 — Surrogate Endpoint (SUR): Blood pressure
Study 18492834 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18492834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18492834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10761170 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20847729 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15297952 — Surrogate Endpoint (SUR): Blood pressure
Study 9566646 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9360002 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9360002 — Surrogate Endpoint (SUR): Blood pressure
Study 28380277 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24631095 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29214353 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 29214353 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29214353 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 27782887 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20810251 — Predictive Biomarker (PRD): UCN3 mRNA
Genes: UCN3; SPC
Study 18256392 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 15964564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15964564 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10482259 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 10482259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29374233 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 20518809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15674510 — Surrogate Endpoint (SUR): Blood pressure
Study 2227553 — Surrogate Endpoint (SUR): Pathological complete response
Study 26043229 — Predictive Biomarker (PRD): GCKR mRNA
Genes: GCKR
Study 11200732 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 19672742 — Surrogate Endpoint (SUR): Bone mineral density
Study 19672742 — Surrogate Endpoint (SUR): Serum calcium
Study 31793630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29056106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17470687 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17470687 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12905875 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3135784 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25050594 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16402915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16402915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16402915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15673102 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23136195 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 23136195 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 21756757 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23132825 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16458316 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1329920 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 20078813 — Surrogate Endpoint (SUR): Blood pressure
Study 16294263 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 27232884 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF