TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8465780 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3008669 — Predictive Biomarker (PRD): SMARCA2 mRNA
Genes: SMARCA2; BAF190B; BRM; SNF2A; SNF2L2
Study 31174600 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26538364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26538364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26538364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24863250 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 22453866 — Surrogate Endpoint (SUR): Serum sodium
Study 10509550 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10509550 — Surrogate Endpoint (SUR): Blood pressure
Study 24615681 — Surrogate Endpoint (SUR): Bone mineral density
Study 23047652 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 17957793 — Predictive Biomarker (PRD): PSCA mRNA
Genes: PSCA; UNQ206/PRO232
Study 1889697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 29861448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24460863 — Safety Biomarker (SAF): BDNF
Study 2505627 — Surrogate Endpoint (SUR): Blood pressure
Study 19506919 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 16681476 — Predictive Biomarker (PRD): SEPTIN3 mRNA
Genes: SEPTIN3; SEP3; SEPT3
Study 11305707 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 9430805 — Surrogate Endpoint (SUR): Blood pressure
Study 31965899 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22749707 — Surrogate Endpoint (SUR): Blood pressure
Study 25884315 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 9610529 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8111257 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8111257 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26521106 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23599381 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 23599381 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 16807142 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 16807142 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1576095 — Surrogate Endpoint (SUR): Blood pressure
Study 19755656 — Predictive Biomarker (PRD): CHRNB2 mRNA
Genes: CHRNB2
Study 16531621 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29633621 — Surrogate Endpoint (SUR): Blood pressure
Study 29633621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24390764 — Surrogate Endpoint (SUR): Blood pressure
Study 21430703 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study 21430703 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH
Study 9296729 — Surrogate Endpoint (SUR): Blood pressure
Study 8409079 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8409079 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28827788 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 28827788 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 28827788 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22070512 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17604453 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 17604453 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 16097050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31646767 — Safety Biomarker (SAF): IL-6 and IL-10
Study 11156490 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 11156490 — Predictive Biomarker (PRD): GRAMD4 mRNA
Genes: GRAMD4; DIP; KIAA0767
Study 31250668 — Surrogate Endpoint (SUR): Blood pressure
Study 26216477 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 26216477 — Predictive Biomarker (PRD): ABL2 mRNA
Genes: ABL2; ABLL; ARG
Study 26216477 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17150221 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 17150221 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 17150221 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15871847 — Surrogate Endpoint (SUR): Blood pressure
Study 16321141 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 16321141 — Surrogate Endpoint (SUR): Blood pressure
Study 8614310 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8614310 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2269032 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 29800130 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 24517173 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10625114 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8749696 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31176287 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 26405104 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 25493942 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 18339792 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25324277 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 11134469 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7930234 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2465447 — Surrogate Endpoint (SUR): Blood pressure
Study 23423269 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11726257 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8030688 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8030688 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2913773 — Surrogate Endpoint (SUR): Blood pressure
Study 2913773 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2124243 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20491957 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15824342 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 1611832 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29250843 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26054202 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 26054202 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 26054202 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 8470059 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31281181 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27129871 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 23684823 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20442581 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20442581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20442581 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16319505 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8807727 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8807727 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8807727 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8807727 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21921224 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9350607 — Surrogate Endpoint (SUR): Serum creatinine
Study 29125700 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 20032170 — Surrogate Endpoint (SUR): Blood pressure
Study 18655841 — Surrogate Endpoint (SUR): Serum potassium
Study 12622932 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12622932 — Monitoring Biomarker (MOI): HBV DNA
Study 31725748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25331262 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25331262 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25331262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25331262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19766760 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11273914 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 21091220 — Surrogate Endpoint (SUR): Blood pressure
Study 11434791 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11434791 — Surrogate Endpoint (SUR): Blood pressure
Study 23840361 — Predictive Biomarker (PRD): MTRR mRNA
Genes: MTRR
Study 23840361 — Predictive Biomarker (PRD): DNMT3B mRNA
Genes: DNMT3B
Study 23840361 — Safety Biomarker (SAF): MTHFR
Study 12879635 — Predictive Biomarker (PRD): CYP46A1 mRNA
Genes: CYP46A1; CYP46
Study 12879635 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 23109680 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 18559364 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18559364 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18559364 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 18559364 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18559364 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 12496750 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 12496750 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 12496750 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12496750 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30431527 — Surrogate Endpoint (SUR): Blood pressure
Study 28650589 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28650589 — Surrogate Endpoint (SUR): Bone mineral density
Study 8688279 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8688279 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29038320 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 26802155 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26802155 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 27137148 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 27137148 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 9876294 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9876294 — Surrogate Endpoint (SUR): Blood pressure
Study 21767103 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31494306 — Surrogate Endpoint (SUR): Blood pressure
Study 22689416 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31558416 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 31558416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31517821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31517821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26883609 — Surrogate Endpoint (SUR): Blood pressure
Study 21144773 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 21144773 — Surrogate Endpoint (SUR): Blood pressure
Study 21144773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21144773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21144773 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19238310 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 16723781 — Predictive Biomarker (PRD): KCNQ1 mRNA
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study 11305263 — Safety Biomarker (SAF): Urinary microalbumin
Study 11305263 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 9053501 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29533368 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 27871564 — Safety Biomarker (SAF): IL-6 and IL-10
Study 24314839 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19027970 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19027970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12149101 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9800666 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12839657 — Surrogate Endpoint (SUR): Blood pressure
Study 30727931 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 8174837 — Surrogate Endpoint (SUR): Blood pressure
Study 31165457 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19538239 — Surrogate Endpoint (SUR): Blood pressure
Study 19538239 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19538239 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19538239 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23944211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11075313 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30589029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25011935 — Monitoring Biomarker (MOI): HBV DNA
Study 1652976 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 1652976 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30781525 — Surrogate Endpoint (SUR): Bone mineral density
Study 31105911 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 23540216 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 23540216 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 8675160 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 8675160 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8675160 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 1562332 — Surrogate Endpoint (SUR): Blood pressure
Study 30219436 — Surrogate Endpoint (SUR): Blood pressure
Study 26059745 — Surrogate Endpoint (SUR): Blood pressure
Study 26059745 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20662624 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 20662624 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 20662624 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 11967719 — Surrogate Endpoint (SUR): Blood pressure
Study 27737326 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2959439 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 29864548 — Surrogate Endpoint (SUR): Blood pressure
Study 10091404 — Safety Biomarker (SAF): UGT1A1
Genes: UGT1A
Study 10091404 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 2161301 — Surrogate Endpoint (SUR): Blood pressure
Study 28973227 — Surrogate Endpoint (SUR): Blood pressure
Study 20829069 — Surrogate Endpoint (SUR): Blood pressure
Study 19391532 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 15487806 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 11230785 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 31686093 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25278093 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25278093 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 25278093 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23445141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19527321 — Surrogate Endpoint (SUR): Blood pressure
Study 31970593 — Surrogate Endpoint (SUR): Serum uric acid
Study 18352852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31060529 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28333093 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 28333093 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 28333093 — Surrogate Endpoint (SUR): Blood pressure
Study 28333093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25049068 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 19938212 — Surrogate Endpoint (SUR): Blood pressure
Study 10994920 — Predictive Biomarker (PRD): PPP1R12A mRNA
Genes: PPP1R12A; MBS; MYPT1
Study 25709685 — Surrogate Endpoint (SUR): Blood pressure
Study 10715359 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 19643946 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27434314 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21890583 — Surrogate Endpoint (SUR): Blood pressure
Study 12370501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12370501 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8567827 — Surrogate Endpoint (SUR): Serum testosterone
Study 23328275 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22333547 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9541433 — Surrogate Endpoint (SUR): Blood pressure
Study 20416236 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 15659079 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 1753598 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30946150 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30946150 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 30946150 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 30946150 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 30946150 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 26858335 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 21542113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23846568 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19345771 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 15320655 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2931973 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 23148287 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18615666 — Surrogate Endpoint (SUR): Serum calcium
Study 31314918 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 21781152 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 3292105 — Surrogate Endpoint (SUR): Blood pressure
Study 26400458 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study 26400458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19038406 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 19038406 — Surrogate Endpoint (SUR): Blood pressure
Study 17307427 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12774855 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10952477 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 28543642 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 19901122 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19901122 — Predictive Biomarker (PRD): Hormone receptor
Study 19901122 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9253136 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 23183440 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 23183440 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23177313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23177313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23177313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21684096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21684096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21684096 — Surrogate Endpoint (SUR): Blood pressure
Study 18444791 — Surrogate Endpoint (SUR): Serum creatinine
Study 16818273 — Predictive Biomarker (PRD): Liver iron
Study 11126524 — Surrogate Endpoint (SUR): Blood pressure
Study 8568271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8568271 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8568271 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 8568271 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21300929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF