TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31958907 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15495826 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 28864691 — Surrogate Endpoint (SUR): Blood pressure
Study 23195627 — Surrogate Endpoint (SUR): Blood pressure
Study 13679934 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8612107 — Surrogate Endpoint (SUR): Blood pressure
Study 1595324 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 6096282 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29454678 — Surrogate Endpoint (SUR): Blood pressure
Study 29454678 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29454678 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25426516 — Surrogate Endpoint (SUR): Blood pressure
Study 19372358 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 27594150 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25751697 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 3524176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30182113 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 30182113 — Predictive Biomarker (PRD): BPIFA2 mRNA
Genes: BPIFA2; C20orf70; SPLUNC2; UNQ510/PRO1025
Study 1543618 — Surrogate Endpoint (SUR): Blood pressure
Study 25224018 — Safety Biomarker (SAF): Hyaluronic acid
Study 17997263 — Surrogate Endpoint (SUR): Blood pressure
Study 12525339 — Surrogate Endpoint (SUR): Blood pressure
Study 31602965 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23569986 — Surrogate Endpoint (SUR): Serum creatinine
Study 12569793 — Surrogate Endpoint (SUR): Serum creatinine
Study 12569793 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30596978 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28060206 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 21353329 — Surrogate Endpoint (SUR): Blood pressure
Study 17544338 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 15163331 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15163331 — Surrogate Endpoint (SUR): Blood pressure
Study 28019686 — Surrogate Endpoint (SUR): Bone mineral density
Study 24277400 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11223449 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10443648 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 10443648 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10443648 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 23446897 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20876346 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 20876346 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 28796313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28796313 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21448304 — Surrogate Endpoint (SUR): Blood pressure
Study 9156357 — Surrogate Endpoint (SUR): Blood pressure
Study 3605732 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3605732 — Surrogate Endpoint (SUR): Blood pressure
Study 18752856 — Safety Biomarker (SAF): Hyaluronic acid
Study 10198901 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 25824533 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 11727293 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 21038649 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17058826 — Monitoring Biomarker (MOI): HBV DNA
Study 6424997 — Surrogate Endpoint (SUR): Blood pressure
Study 31516127 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10613424 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 25440797 — Surrogate Endpoint (SUR): Blood pressure
Study 12868045 — Surrogate Endpoint (SUR): Blood pressure
Study 7491378 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 8886414 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8886414 — Surrogate Endpoint (SUR): Blood pressure
Study 1860682 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 22664804 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 20857772 — Surrogate Endpoint (SUR): Blood pressure
Study 30395021 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 30395021 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19787388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19787388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19787388 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17520260 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 9349604 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26899387 — Surrogate Endpoint (SUR): Serum calcium
Study 2702989 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27332770 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 17391565 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10511135 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10511135 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7910207 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28929359 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24674384 — Surrogate Endpoint (SUR): Serum calcium
Study 24674384 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22719796 — Surrogate Endpoint (SUR): Serum creatinine
Study 18417517 — Surrogate Endpoint (SUR): Bone mineral density
Study 12002290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12002290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12002290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12002290 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 12002290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7754792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25471273 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 9270561 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17209328 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17209328 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8967882 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26568032 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 16078036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 12494080 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10367046 — Surrogate Endpoint (SUR): Bone mineral density
Study 7499031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7499031 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 7499031 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6780232 — Surrogate Endpoint (SUR): Blood pressure
Study 12198018 — Surrogate Endpoint (SUR): Bone mineral density
Study 10200128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3969541 — Surrogate Endpoint (SUR): Blood pressure
Study 26299677 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17012873 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24593273 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22536073 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22536073 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22536073 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22536073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12578516 — Surrogate Endpoint (SUR): Blood pressure
Study 10563072 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1737346 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1737346 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 1737346 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12493085 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 28368672 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 14597860 — Surrogate Endpoint (SUR): Blood pressure
Study 14597860 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10954007 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 10954007 — Surrogate Endpoint (SUR): Blood pressure
Study 1421877 — Surrogate Endpoint (SUR): Blood pressure
Study 30107967 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 24330475 — Monitoring Biomarker (MOI): HBV DNA
Study 7880949 — Surrogate Endpoint (SUR): Blood pressure
Study 9883403 — Surrogate Endpoint (SUR): Blood pressure
Study 10631762 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7595708 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 382821 — Surrogate Endpoint (SUR): Blood pressure
Study 30571659 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 28857719 — Surrogate Endpoint (SUR): Blood pressure
Study 23610455 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19344191 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11793037 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9408981 — Surrogate Endpoint (SUR): Serum creatinine
Study 29354950 — Surrogate Endpoint (SUR): Blood pressure
Study 23713578 — Surrogate Endpoint (SUR): Blood pressure
Study 16239314 — Safety Biomarker (SAF): Reactive oxygen species
Study 8305662 — Surrogate Endpoint (SUR): Serum creatinine
Study 28866091 — Surrogate Endpoint (SUR): Blood pressure
Study 22412088 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22412088 — Safety Biomarker (SAF): Reactive oxygen species
Study 20079863 — Predictive Biomarker (PRD): Liver iron
Study 12504694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 26112283 — Surrogate Endpoint (SUR): Blood pressure
Study 17160498 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16887430 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 16887430 — Surrogate Endpoint (SUR): Serum creatinine
Study 15312472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15312472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10914936 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21107327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21107327 — Surrogate Endpoint (SUR): Blood pressure
Study 21107327 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19099689 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 1492852 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 19143907 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 17314057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12651657 — Surrogate Endpoint (SUR): Blood pressure
Study 7851372 — Surrogate Endpoint (SUR): Plasma ammonia
Study 14656749 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3206197 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 16464519 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2962005 — Surrogate Endpoint (SUR): Blood pressure
Study 31952145 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31952145 — Safety Biomarker (SAF): BDNF
Study 31138315 — Surrogate Endpoint (SUR): Blood pressure
Study 15507059 — Surrogate Endpoint (SUR): Bone mineral density
Study 9270084 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31617649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31617649 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 28554732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28554732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28554732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28554732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25629740 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20697417 — Surrogate Endpoint (SUR): Blood pressure
Study 12577156 — Surrogate Endpoint (SUR): Blood pressure
Study 8923356 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3887852 — Surrogate Endpoint (SUR): Blood pressure
Study 26494876 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9237290 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9237290 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9237290 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9237290 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8338977 — Surrogate Endpoint (SUR): Serum calcium
Study 22543739 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22543739 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22543739 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 17645559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23765755 — Surrogate Endpoint (SUR): Blood pressure
Study 21319341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9707350 — Surrogate Endpoint (SUR): Blood pressure
Study 22686074 — Surrogate Endpoint (SUR): Serum creatinine
Study 31232917 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 28381198 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21737787 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11124134 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10966534 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1609752 — Surrogate Endpoint (SUR): Serum testosterone
Study 29167971 — Surrogate Endpoint (SUR): Bone mineral density
Study 23756850 — Monitoring Biomarker (MOI): HBV DNA
Study 10329342 — Surrogate Endpoint (SUR): Blood pressure
Study 7866989 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 28142296 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24685414 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15333734 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 21118735 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16368293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16368293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16368293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16368293 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16368293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16368293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15753186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10992331 — Surrogate Endpoint (SUR): Serum sodium
Study 27404516 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24944063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24944063 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22939358 — Surrogate Endpoint (SUR): Blood pressure
Study 8780817 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8780817 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29710289 — Surrogate Endpoint (SUR): Blood pressure
Study 17405995 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19927136 — Surrogate Endpoint (SUR): Blood pressure
Study 15957843 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15957843 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12048138 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 12048138 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 21292625 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 21158218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8061720 — Surrogate Endpoint (SUR): Blood pressure
Study 15291288 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 3286173 — Surrogate Endpoint (SUR): Blood pressure
Study 17313803 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 17313803 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 12682082 — Surrogate Endpoint (SUR): Blood pressure
Study 24902920 — Surrogate Endpoint (SUR): Blood pressure
Study 19528834 — Surrogate Endpoint (SUR): Blood pressure
Study 22354147 — Surrogate Endpoint (SUR): Blood pressure
Study 19005405 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 19005405 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19391530 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 30865529 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30865529 — Surrogate Endpoint (SUR): Blood pressure
Study 24257813 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 24257813 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22534049 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19875426 — Surrogate Endpoint (SUR): Blood pressure
Study 11207051 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11207051 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8177971 — Surrogate Endpoint (SUR): Blood pressure
Study 8177971 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2444132 — Surrogate Endpoint (SUR): Blood pressure
Study 1981681 — Surrogate Endpoint (SUR): Blood pressure
Study 1981681 — Surrogate Endpoint (SUR): Serum potassium
Study 1981681 — Surrogate Endpoint (SUR): Serum uric acid
Study 21266204 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 307810 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 24780946 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12969695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2065688 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1795202 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1795202 — Surrogate Endpoint (SUR): Blood pressure
Study 19222610 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19222610 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8914492 — Surrogate Endpoint (SUR): Bone mineral density
Study 31471309 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31471309 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 24633809 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 24633809 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24633809 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 1394200 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 1394200 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3924065 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26746868 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16358411 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 16358411 — Surrogate Endpoint (SUR): Serum creatinine
Study 30538436 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 30538436 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 26915630 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27100654 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 23579624 — Surrogate Endpoint (SUR): Blood pressure
Study 21913547 — Surrogate Endpoint (SUR): Blood pressure
Study 17100775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17100775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10897972 — Surrogate Endpoint (SUR): Serum testosterone
Study 20530082 — Surrogate Endpoint (SUR): Blood pressure