TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9041945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3503941 — Surrogate Endpoint (SUR): Blood pressure
Study 8919897 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8919897 — Surrogate Endpoint (SUR): Blood pressure
Study 7051805 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 7051805 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 27704143 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21878488 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 7923304 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31465093 — Predictive Biomarker (PRD): Hormone receptor
Study 31465093 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29113664 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 25350224 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24267513 — Surrogate Endpoint (SUR): Serum creatinine
Study 17187417 — Monitoring Biomarker (MOI): HBV DNA
Study 26077412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26077412 — Surrogate Endpoint (SUR): Bone mineral density
Study 15367067 — Surrogate Endpoint (SUR): Blood pressure
Study 10879554 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30487976 — Surrogate Endpoint (SUR): Blood pressure
Study 23899653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23899653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10426331 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 19185400 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 19185400 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 6786825 — Surrogate Endpoint (SUR): Blood pressure
Study 23770110 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 8908377 — Surrogate Endpoint (SUR): Blood pressure
Study 6126126 — Surrogate Endpoint (SUR): Blood pressure
Study 8137435 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 8137435 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 21155616 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21155616 — Surrogate Endpoint (SUR): Blood pressure
Study 21155616 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12490768 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 25480461 — Surrogate Endpoint (SUR): Blood pressure
Study 17570513 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 12187208 — Surrogate Endpoint (SUR): Serum testosterone
Study 22820210 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19083502 — Safety Biomarker (SAF): Hyaluronic acid
Study 16562817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29528443 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 24760645 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20231783 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 20231783 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 31504417 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 31504417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20171327 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 21871624 — Predictive Biomarker (PRD): KIF6 mRNA
Genes: KIF6; C6orf102
Study 15097153 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10696916 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10696916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10696916 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10696916 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30871349 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22015082 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 7527106 — Surrogate Endpoint (SUR): Blood pressure
Study 20962664 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 20962664 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15541248 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11853286 — Surrogate Endpoint (SUR): Bone mineral density
Study 22615116 — Surrogate Endpoint (SUR): Blood pressure
Study 20666265 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 20666265 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11804978 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 31375380 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31375380 — Safety Biomarker (SAF): BDNF
Study 20054294 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study 20054294 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 1414144 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28294535 — Safety Biomarker (SAF): Hyaluronic acid
Study 17577460 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10326113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10326113 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 7653825 — Surrogate Endpoint (SUR): Serum creatinine
Study 2551088 — Surrogate Endpoint (SUR): Blood pressure
Study 11277173 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 11277173 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9863499 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9863499 — Predictive Biomarker (PRD): A1CF mRNA
Genes: A1CF; ACF; ASP
Study 31619234 — Surrogate Endpoint (SUR): Blood pressure
Study 27221864 — Predictive Biomarker (PRD): SULT1A1 mRNA
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 27221864 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31604589 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 31604589 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 18981188 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 15335180 — Surrogate Endpoint (SUR): Blood pressure
Study 6387613 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31659655 — Surrogate Endpoint (SUR): Blood pressure
Study 10362894 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 14624403 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 22134152 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22134152 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15827896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15827896 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24124428 — Surrogate Endpoint (SUR): Blood pressure
Study 19221039 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 19221039 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 19221039 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 19221039 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8181024 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28766349 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20732799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20732799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16776849 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 30099402 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 17610527 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17610527 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 11115156 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9154995 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8425695 — Surrogate Endpoint (SUR): Serum creatinine
Study 8425695 — Surrogate Endpoint (SUR): Blood pressure
Study 3322166 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3322166 — Surrogate Endpoint (SUR): Blood pressure
Study 30243294 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8972000 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 2861219 — Surrogate Endpoint (SUR): Blood pressure
Study 24391822 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24391822 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 7052613 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 25200559 — Surrogate Endpoint (SUR): Blood pressure
Study 17725934 — Surrogate Endpoint (SUR): Blood pressure
Study 12186124 — Surrogate Endpoint (SUR): Serum creatinine
Study 100866 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 15131431 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9649661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8021472 — Surrogate Endpoint (SUR): Blood pressure
Study 8021472 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18379218 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18379218 — Safety Biomarker (SAF): BDNF
Study 10532588 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 19679580 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7424927 — Surrogate Endpoint (SUR): Blood pressure
Study 31699052 — Safety Biomarker (SAF): IL-6 and IL-10
Study 30113724 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 30113724 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 30113724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11594643 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9855387 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16758733 — Monitoring Biomarker (MOI): Procalcitonin
Study 10556117 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8561059 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1927294 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 28241822 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28241822 — Surrogate Endpoint (SUR): Blood pressure
Study 15031131 — Surrogate Endpoint (SUR): Blood pressure
Study 31515704 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2943752 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 23752109 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8671965 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8671965 — Surrogate Endpoint (SUR): Serum creatinine
Study 1834065 — Surrogate Endpoint (SUR): Blood pressure
Study 7134845 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27096878 — Surrogate Endpoint (SUR): Bone mineral density
Study 24937669 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22190136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22190136 — Surrogate Endpoint (SUR): Bone mineral density
Study 20567133 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20567133 — Surrogate Endpoint (SUR): Blood pressure
Study 11130129 — Surrogate Endpoint (SUR): Blood pressure
Study 18925510 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 8882074 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1430301 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 3005756 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18319697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18319697 — Safety Biomarker (SAF): Reactive oxygen species
Study 18661258 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 27173814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12552351 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 7546496 — Surrogate Endpoint (SUR): Blood pressure
Study 24123094 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20200041 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 1415200 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 3905211 — Surrogate Endpoint (SUR): Blood pressure
Study 24823465 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20144231 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20144231 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18394099 — Surrogate Endpoint (SUR): Blood pressure
Study 12722398 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 8116037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8116037 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8116037 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 8116037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8116037 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1069551 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 30021394 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30021394 — Surrogate Endpoint (SUR): Blood pressure
Study 30021394 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12492612 — Surrogate Endpoint (SUR): Blood pressure
Study 2790218 — Predictive Biomarker (PRD): RARS1 mRNA
Genes: RARS1; RARS
Study 21827215 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 21827215 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 14736787 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11776596 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 6151506 — Surrogate Endpoint (SUR): Blood pressure
Study 23535809 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 15914049 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 11106307 — Surrogate Endpoint (SUR): Blood pressure
Study 24519039 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 10577621 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 3034017 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3034017 — Surrogate Endpoint (SUR): Blood pressure
Study 27665708 — Surrogate Endpoint (SUR): Blood pressure
Study 19567528 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 21664068 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 21664068 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 10737166 — Surrogate Endpoint (SUR): Blood pressure
Study 9186317 — Surrogate Endpoint (SUR): Urinary oxalate
Study 30374129 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 27171324 — Surrogate Endpoint (SUR): Serum potassium
Study 20191257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 18360047 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18360047 — Surrogate Endpoint (SUR): Blood pressure
Study 12638278 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7288877 — Surrogate Endpoint (SUR): Serum potassium
Study 27097389 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 20882405 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20882405 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12419572 — Surrogate Endpoint (SUR): Blood pressure
Study 27097156 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 27097156 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27421051 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21989330 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 21989330 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 15750041 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 15750041 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20696047 — Surrogate Endpoint (SUR): Blood pressure
Study 12882706 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 12882706 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12882706 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10999794 — Surrogate Endpoint (SUR): Bone mineral density
Study 21883497 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15207950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9710873 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3241870 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 30204280 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8010457 — Surrogate Endpoint (SUR): Blood pressure
Study 31821667 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21508170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19052126 — Monitoring Biomarker (MOI): HBV DNA
Study 8400608 — Surrogate Endpoint (SUR): Bone mineral density
Study 29664663 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29664663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24812434 — Surrogate Endpoint (SUR): Blood pressure
Study 22921287 — Surrogate Endpoint (SUR): Blood pressure
Study 19321990 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 15362205 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 11848262 — Surrogate Endpoint (SUR): Blood pressure
Study 10437260 — Predictive Biomarker (PRD): PLEK mRNA
Genes: PLEK; P47
Study 3279578 — Surrogate Endpoint (SUR): Serum creatinine
Study 29221470 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 19671875 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 19671875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 19671875 — Predictive Biomarker (PRD): NQO2 mRNA
Genes: NQO2; NMOR2
Study 19671875 — Predictive Biomarker (PRD): CBR3 mRNA
Genes: CBR3; SDR21C2
Study 9135704 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7963510 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7963510 — Surrogate Endpoint (SUR): Blood pressure
Study 2252171 — Surrogate Endpoint (SUR): Blood pressure
Study 31259 — Surrogate Endpoint (SUR): Blood pressure
Study 31259 — Surrogate Endpoint (SUR): Serum creatinine
Study 26080370 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9727571 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2140663 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 24100786 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24100786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24100786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24100786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21757515 — Predictive Biomarker (PRD): GPSM2 mRNA
Genes: GPSM2; LGN
Study 15477049 — Surrogate Endpoint (SUR): Blood pressure
Study 11926203 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11926203 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7989900 — Surrogate Endpoint (SUR): Blood pressure
Study 1233216 — Surrogate Endpoint (SUR): Blood pressure
Study 31486684 — Surrogate Endpoint (SUR): Bone mineral density
Study 26195078 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 25205516 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 4469040 — Surrogate Endpoint (SUR): Blood pressure
Study 28000180 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25583994 — Predictive Biomarker (PRD): ADCY9 mRNA
Genes: ADCY9; KIAA0520
Study 25583994 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22947258 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17602078 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9420397 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 29404806 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29404806 — Predictive Biomarker (PRD): Hormone receptor
Study 18996856 — Surrogate Endpoint (SUR): Blood pressure
Study 11040224 — Surrogate Endpoint (SUR): Blood pressure
Study 31504526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8297739 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7975663 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 7975663 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 378671 — Surrogate Endpoint (SUR): Blood pressure
Study 28039187 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 26028098 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24382103 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11427642 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1