TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18236372 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31969155 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 24825642 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 24825642 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23186260 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 23186260 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 20693158 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20693158 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10713636 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29661838 — Safety Biomarker (SAF): Reactive oxygen species
Study 29661838 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16574893 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 16574893 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16574893 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11789169 — Surrogate Endpoint (SUR): Serum creatinine
Study 11789169 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 23410186 — Surrogate Endpoint (SUR): Blood pressure
Study 21085038 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19910821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21986283 — Surrogate Endpoint (SUR): Blood pressure
Study 9548208 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8035933 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 27475733 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 20150004 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12810695 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7093095 — Surrogate Endpoint (SUR): Blood pressure
Study 26911438 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 26464863 — Surrogate Endpoint (SUR): Serum creatinine
Study 27815860 — Safety Biomarker (SAF): Reactive oxygen species
Study 23216760 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23216760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21670398 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21670398 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 16492813 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 16492813 — Surrogate Endpoint (SUR): Blood pressure
Study 9129086 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30586723 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 3925478 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30910755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16927289 — Monitoring Biomarker (MOI): HBV DNA
Study 27020170 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 24424705 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 16898862 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12830407 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30554883 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28454806 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 10021880 — Surrogate Endpoint (SUR): Blood pressure
Study 31537225 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31537225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24378322 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 24378322 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19540365 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2036894 — Surrogate Endpoint (SUR): Serum calcium
Study 25954110 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 20922535 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20922535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20922535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19036057 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 17014595 — Surrogate Endpoint (SUR): Blood pressure
Study 8022739 — Surrogate Endpoint (SUR): Blood pressure
Study 24075764 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24075764 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15098379 — Surrogate Endpoint (SUR): Bone mineral density
Study 11783326 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28261001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28261001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21331459 — Surrogate Endpoint (SUR): Blood pressure
Study 16112299 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31615471 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15530150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15530150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15530150 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7841566 — Surrogate Endpoint (SUR): Blood pressure
Study 28448784 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11011847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8339552 — Surrogate Endpoint (SUR): Blood pressure
Study 8339552 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25008027 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12672938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12672938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22484582 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22484582 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 22484582 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 11943519 — Surrogate Endpoint (SUR): Blood pressure
Study 23174856 — Surrogate Endpoint (SUR): Blood pressure
Study 15753134 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26073279 — Surrogate Endpoint (SUR): Blood pressure
Study 24322572 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 22665339 — Surrogate Endpoint (SUR): Serum sodium
Study 7913326 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11989569 — Surrogate Endpoint (SUR): Blood pressure
Study 10856393 — Surrogate Endpoint (SUR): Blood pressure
Study 30280657 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 26944023 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 26944023 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 26944023 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28599629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24589564 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 24589564 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24589564 — Surrogate Endpoint (SUR): Blood pressure
Study 24589564 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17638657 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 10223783 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10223783 — Surrogate Endpoint (SUR): Blood pressure
Study 359019 — Surrogate Endpoint (SUR): Blood pressure
Study 359019 — Surrogate Endpoint (SUR): Serum uric acid
Study 359019 — Surrogate Endpoint (SUR): Serum creatinine
Study 17563030 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11605698 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11605698 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27451978 — Predictive Biomarker (PRD): ULK2 mRNA
Genes: ULK2; KIAA0623
Study 27451978 — Predictive Biomarker (PRD): RGS6 mRNA
Genes: RGS6
Study 25527735 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 16144857 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 16144857 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 8819499 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 2864935 — Surrogate Endpoint (SUR): Blood pressure
Study 26325116 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 20082756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16547384 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 2044783 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 25935584 — Surrogate Endpoint (SUR): Bone mineral density
Study 23393176 — Surrogate Endpoint (SUR): Blood pressure
Study 29846653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10937984 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30558054 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 27651323 — Safety Biomarker (SAF): Reactive oxygen species
Study 1901635 — Surrogate Endpoint (SUR): Blood pressure
Study 16215308 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 16215308 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16215308 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11498451 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 11498451 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 28839342 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 9443652 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8393585 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8393585 — Surrogate Endpoint (SUR): Blood pressure
Study 27871603 — Surrogate Endpoint (SUR): Blood pressure
Study 19011472 — Surrogate Endpoint (SUR): Bone mineral density
Study 19011472 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 19011472 — Surrogate Endpoint (SUR): Serum calcium
Study 15738450 — Surrogate Endpoint (SUR): Blood pressure
Study 12925557 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3786346 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 3786346 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 31021381 — Predictive Biomarker (PRD): ACAD10 mRNA
Genes: ACAD10
Study 8846749 — Predictive Biomarker (PRD): PCSK7 mRNA
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 23039313 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 23039313 — Surrogate Endpoint (SUR): Serum phosphate
Study 23039313 — Surrogate Endpoint (SUR): Serum potassium
Study 23039313 — Surrogate Endpoint (SUR): Blood pressure
Study 2657105 — Surrogate Endpoint (SUR): Blood pressure
Study 2657105 — Surrogate Endpoint (SUR): Serum testosterone
Study 29847672 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 29847672 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 17414674 — Surrogate Endpoint (SUR): Blood pressure
Study 9806657 — Surrogate Endpoint (SUR): Serum creatinine
Study 25872929 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 16436174 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 28640772 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28640772 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19170716 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 19170716 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19170716 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17309907 — Surrogate Endpoint (SUR): Blood pressure
Study 31251544 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31251544 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19541477 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9796240 — Surrogate Endpoint (SUR): Blood pressure
Study 7704460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19352587 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18069280 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 24794451 — Surrogate Endpoint (SUR): Blood pressure
Study 21029429 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 12029546 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19913145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19913145 — Surrogate Endpoint (SUR): Blood pressure
Study 19913145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19913145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16762627 — Monitoring Biomarker (MOI): HBV DNA
Study 31286727 — Surrogate Endpoint (SUR): Blood pressure
Study 23796707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19353407 — Surrogate Endpoint (SUR): Blood pressure
Study 19353407 — Surrogate Endpoint (SUR): Serum creatinine
Study 19353407 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11117873 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 8419001 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8419001 — Surrogate Endpoint (SUR): Blood pressure
Study 24286472 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26397982 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 10720544 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10720544 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10720544 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 27317303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23021433 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 18505468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10085416 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 7828385 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28682681 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28682681 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28682681 — Predictive Biomarker (PRD): Hormone receptor
Study 28682681 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 23662047 — Surrogate Endpoint (SUR): Blood pressure
Study 21566261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17698861 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 9380271 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 28339166 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 12459668 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 12459668 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 12459668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27254026 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24459063 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22781570 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22781570 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15675894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15675894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15675894 — Safety Biomarker (SAF): Interleukin 1
Study 15675894 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9630382 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9630382 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29627608 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23813627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22241764 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15213209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15213209 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 15213209 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15213209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10670838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9493699 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9493699 — Surrogate Endpoint (SUR): Blood pressure
Study 7687157 — Surrogate Endpoint (SUR): Blood pressure
Study 16712431 — Surrogate Endpoint (SUR): Blood pressure
Study 9217590 — Surrogate Endpoint (SUR): Blood pressure
Study 8353352 — Surrogate Endpoint (SUR): Blood pressure
Study 27160639 — Surrogate Endpoint (SUR): Blood pressure
Study 23786940 — Surrogate Endpoint (SUR): Blood pressure
Study 18822094 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20354684 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 773498 — Surrogate Endpoint (SUR): Blood pressure
Study 15902724 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 1672049 — Surrogate Endpoint (SUR): Blood pressure
Study 28346969 — Surrogate Endpoint (SUR): Sperm parameters
Study 17786691 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 15117902 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12081984 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 28319552 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 28319552 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25890186 — Predictive Biomarker (PRD): PALM mRNA
Genes: PALM; KIAA0270
Study 17253179 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 11483325 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11720833 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11720833 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9159837 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9159837 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 9159837 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9159837 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9159837 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 1284159 — Surrogate Endpoint (SUR): Blood pressure
Study 29257777 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 16635623 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 3304930 — Surrogate Endpoint (SUR): Blood pressure
Study 18070947 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9107294 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9107294 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25498245 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 25498245 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 22776413 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21936735 — Predictive Biomarker (PRD): PELI1 mRNA
Genes: PELI1; PRISM
Study 17307749 — Surrogate Endpoint (SUR): Bone mineral density
Study 17307749 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 7955935 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26796694 — Surrogate Endpoint (SUR): Blood pressure
Study 23835818 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26383099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22329674 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 22329674 — Surrogate Endpoint (SUR): Serum calcium
Study 2551805 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2551805 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 21885885 — Surrogate Endpoint (SUR): Blood pressure
Study 17391323 — Surrogate Endpoint (SUR): Blood pressure
Study 29022387 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 29022387 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23578600 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21282434 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18215332 — Surrogate Endpoint (SUR): Bone mineral density
Study 17015058 — Surrogate Endpoint (SUR): Blood pressure
Study 8178906 — Surrogate Endpoint (SUR): Blood pressure
Study 8178906 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol