TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22493073 — Surrogate Endpoint (SUR): Blood pressure
Study 8393365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25909463 — Surrogate Endpoint (SUR): Blood pressure
Study 21219391 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18502262 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18502262 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9175683 — Surrogate Endpoint (SUR): Blood pressure
Study 31839677 — Predictive Biomarker (PRD): DUSP4 mRNA
Genes: DUSP4; MKP2; VH2
Study 31839677 — Predictive Biomarker (PRD): ETV4 mRNA
Genes: ETV4; E1AF; PEA3
Study 18555932 — Surrogate Endpoint (SUR): Blood pressure
Study 21885077 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17854028 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17854028 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26148007 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 26148007 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24019080 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 20683457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18460997 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 1414967 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 23508598 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study 10778966 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 1523877 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 2994989 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2994989 — Surrogate Endpoint (SUR): Blood pressure
Study 31771407 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 31771407 — Predictive Biomarker (PRD): IRX3 mRNA
Genes: IRX3; IRXB1
Study 22474933 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 11239759 — Predictive Biomarker (PRD): TWIST1 mRNA
Genes: TWIST1; BHLHA38; TWIST
Study 24944062 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 24944062 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 9800234 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 22230999 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 31125308 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 21419169 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21419169 — Safety Biomarker (SAF): N-acetylneuraminic acid
Study 11213852 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25769357 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 25769357 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 30982443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20184129 — Surrogate Endpoint (SUR): Blood pressure
Study 31087564 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28289237 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 28289237 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 26411504 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16448895 — Surrogate Endpoint (SUR): Blood pressure
Study 16448895 — Surrogate Endpoint (SUR): Serum uric acid
Study 16448895 — Surrogate Endpoint (SUR): Serum creatinine
Study 2872804 — Surrogate Endpoint (SUR): Blood pressure
Study 9284777 — Surrogate Endpoint (SUR): Bone mineral density
Study 8392359 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17226852 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16114787 — Surrogate Endpoint (SUR): Serum creatinine
Study 12134227 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1536959 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15073109 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15073109 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17961161 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 14636765 — Surrogate Endpoint (SUR): Bacterial count
Study 18042053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12095058 — Surrogate Endpoint (SUR): Bone mineral density
Study 12095058 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30767253 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30767253 — Surrogate Endpoint (SUR): Blood pressure
Study 21296603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16412857 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16412857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16412857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16412857 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29125992 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10407881 — Surrogate Endpoint (SUR): Blood pressure
Study 7750306 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 21352660 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22550938 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7007060 — Surrogate Endpoint (SUR): Blood pressure
Study 19818223 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11961019 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9405732 — Surrogate Endpoint (SUR): Bone mineral density
Study 2668462 — Surrogate Endpoint (SUR): Blood pressure
Study 31220863 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22117841 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18562790 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18562790 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 27173472 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 27173472 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20738456 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31721892 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31721892 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 31721892 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 31721892 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 31721892 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 31721892 — Safety Biomarker (SAF): BDNF
Study 29071931 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 17971285 — Surrogate Endpoint (SUR): Bone mineral density
Study 21629249 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 19081527 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30736832 — Surrogate Endpoint (SUR): Blood pressure
Study 30953791 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 24046302 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21898590 — Surrogate Endpoint (SUR): Bone mineral density
Study 2916452 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 26303628 — Surrogate Endpoint (SUR): Bone mineral density
Study 19334068 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 19334068 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15948237 — Monitoring Biomarker (MOI): HBV DNA
Study 29650706 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 29650706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29650706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29650706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19766209 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23357149 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21343239 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10828731 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 7917158 — Surrogate Endpoint (SUR): Blood pressure
Study 7917158 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31792258 — Surrogate Endpoint (SUR): Pathological complete response
Study 1557681 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 3891615 — Surrogate Endpoint (SUR): Blood pressure
Study 24885096 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 19903661 — Surrogate Endpoint (SUR): Blood pressure
Study 10610644 — Surrogate Endpoint (SUR): Bone mineral density
Study 21940091 — Surrogate Endpoint (SUR): Blood pressure
Study 12459865 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20060192 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20060192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 15452689 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 11849315 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 11849315 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9408071 — Surrogate Endpoint (SUR): Blood pressure
Study 12681875 — Surrogate Endpoint (SUR): Bone mineral density
Study 8864323 — Surrogate Endpoint (SUR): Serum calcium
Study 21041432 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21041432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31359143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28002688 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21924882 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11085323 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29779262 — Predictive Biomarker (PRD): SPRR1A mRNA
Genes: SPRR1A
Study 29779262 — Predictive Biomarker (PRD): TET3 mRNA
Genes: TET3; KIAA0401
Study 29779262 — Predictive Biomarker (PRD): FAM25A mRNA
Genes: FAM25A
Study 29779262 — Predictive Biomarker (PRD): CRCT1 mRNA
Genes: CRCT1; C1orf42; NICE1
Study 24714489 — Surrogate Endpoint (SUR): Serum creatinine
Study 23970114 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 23970114 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 10999788 — Surrogate Endpoint (SUR): Bone mineral density
Study 10999788 — Surrogate Endpoint (SUR): Serum calcium
Study 8636808 — Surrogate Endpoint (SUR): Blood pressure
Study 1512513 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30012185 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30012185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26728060 — Surrogate Endpoint (SUR): Blood pressure
Study 22178174 — Surrogate Endpoint (SUR): Serum creatinine
Study 15745726 — Surrogate Endpoint (SUR): Blood pressure
Study 14619641 — Surrogate Endpoint (SUR): Bone mineral density
Study 12078788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12078788 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2636677 — Surrogate Endpoint (SUR): Serum creatinine
Study 16877197 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16877197 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27344822 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27344822 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27344822 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22388234 — Surrogate Endpoint (SUR): Serum uric acid
Study 15676086 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19022155 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 12610862 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 10234295 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25149383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 25149383 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16194475 — Surrogate Endpoint (SUR): Blood pressure
Study 27118107 — Predictive Biomarker (PRD): MYCL mRNA
Genes: MYCL; BHLHE38; LMYC; MYCL1
Study 27118107 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23283367 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18434729 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10704624 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 10704624 — Safety Biomarker (SAF): MTHFR
Study 25286914 — Surrogate Endpoint (SUR): Blood pressure
Study 12648865 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10488413 — Monitoring Biomarker (MOI): HBV DNA
Study 1872724 — Surrogate Endpoint (SUR): Blood pressure
Study 31095287 — Surrogate Endpoint (SUR): Pathological complete response
Study 11295959 — Surrogate Endpoint (SUR): Blood pressure
Study 9168293 — Surrogate Endpoint (SUR): Blood pressure
Study 8287830 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2215101 — Surrogate Endpoint (SUR): Blood pressure
Study 17719703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9846802 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25914483 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25914483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20649626 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 20649626 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20649626 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12791813 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9126796 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3908126 — Surrogate Endpoint (SUR): Blood pressure
Study 25828624 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 25828624 — Surrogate Endpoint (SUR): Blood pressure
Study 29772114 — Safety Biomarker (SAF): Hyaluronic acid
Study 6670341 — Surrogate Endpoint (SUR): Blood pressure
Study 27484299 — Surrogate Endpoint (SUR): Blood pressure
Study 21226769 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20681279 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 1771284 — Surrogate Endpoint (SUR): Blood pressure
Study 31801326 — Surrogate Endpoint (SUR): Blood pressure
Study 16443859 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16443859 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 16443859 — Surrogate Endpoint (SUR): Blood pressure
Study 16443859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30891524 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 21955937 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21955937 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16923416 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22517293 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22517293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20683147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20683147 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20683147 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31996370 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29660421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26718934 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7971012 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2893635 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30506579 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 26039534 — Surrogate Endpoint (SUR): Blood pressure
Study 14679156 — Surrogate Endpoint (SUR): Serum creatinine
Study 3789297 — Surrogate Endpoint (SUR): Blood pressure
Study 27742226 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 27742226 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24667300 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8780542 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1610866 — Surrogate Endpoint (SUR): Blood pressure
Study 24929461 — Surrogate Endpoint (SUR): Blood pressure
Study 10207506 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 7789626 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21043792 — Surrogate Endpoint (SUR): Probing pocket depth
Study 14722148 — Surrogate Endpoint (SUR): Blood pressure
Study 8147341 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28748974 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 28748974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21725875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21725875 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21725875 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19526433 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 7932515 — Surrogate Endpoint (SUR): Blood pressure
Study 22978615 — Surrogate Endpoint (SUR): Blood pressure
Study 21807659 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 16441926 — Surrogate Endpoint (SUR): Blood pressure
Study 16441926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16441926 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9408067 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29493058 — Surrogate Endpoint (SUR): Blood pressure
Study 22018760 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19818562 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19818562 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 16202862 — Surrogate Endpoint (SUR): Blood pressure
Study 2221579 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 532631 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10836489 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9277075 — Surrogate Endpoint (SUR): Blood pressure
Study 23287080 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16908915 — Surrogate Endpoint (SUR): Serum creatinine
Study 29549829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11704101 — Surrogate Endpoint (SUR): Blood pressure
Study 26552352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26552352 — Surrogate Endpoint (SUR): Serum creatinine
Study 23299767 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16642619 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26269653 — Surrogate Endpoint (SUR): Blood pressure
Study 10577447 — Surrogate Endpoint (SUR): Blood pressure
Study 1752290 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 1752290 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27720613 — Surrogate Endpoint (SUR): Blood pressure
Study 24239881 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 22923753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15367197 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19590022 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1461620 — Predictive Biomarker (PRD): Hormone receptor
Study 20406780 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16205441 — Surrogate Endpoint (SUR): Blood pressure
Study 21450574 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 2649221 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 30354794 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 3017723 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25361054 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 24819981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24819981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20395261 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20395261 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30189612 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26309191 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16731324 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16731324 — Surrogate Endpoint (SUR): Blood pressure
Study 11736724 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 26590384 — Surrogate Endpoint (SUR): Blood pressure