TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24796339 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16566082 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10409573 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31643039 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21719902 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19944359 — Surrogate Endpoint (SUR): Blood pressure
Study 15155466 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 26582873 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24157526 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24157526 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24157526 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 24157526 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 19339045 — Surrogate Endpoint (SUR): Blood pressure
Study 9020593 — Surrogate Endpoint (SUR): Blood pressure
Study 6540047 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 25582793 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22155918 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22155918 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22155918 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23159393 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 14623504 — Surrogate Endpoint (SUR): Blood pressure
Study 23801606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23801606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23801606 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16421364 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10843145 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10843145 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30367021 — Surrogate Endpoint (SUR): Blood pressure
Study 27737602 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15984576 — Predictive Biomarker (PRD): CPVL mRNA
Genes: CPVL; VLP; PSEC0124; UNQ197/PRO223
Study 8913544 — Surrogate Endpoint (SUR): Blood pressure
Study 30203839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30203839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18547426 — Surrogate Endpoint (SUR): Bone mineral density
Study 8524984 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2273527 — Surrogate Endpoint (SUR): Blood pressure
Study 30531304 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 25935581 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 24085466 — Safety Biomarker (SAF): Hyaluronic acid
Study 9521833 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 8110557 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21450118 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 3051870 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15844319 — Surrogate Endpoint (SUR): Serum creatinine
Study 2160343 — Surrogate Endpoint (SUR): Blood pressure
Study 23322362 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23322362 — Surrogate Endpoint (SUR): Bone mineral density
Study 17717918 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 27190323 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27190323 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 7512336 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7555472 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23563932 — Surrogate Endpoint (SUR): Bone mineral density
Study 19166691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19166691 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29634656 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 29634656 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16554145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26852885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26852885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26852885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26852885 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18376061 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 7442597 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20635803 — Surrogate Endpoint (SUR): Blood pressure
Study 17477205 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 30696807 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 26407169 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30169436 — Surrogate Endpoint (SUR): Blood pressure
Study 17299464 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 31264758 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 31264758 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27199314 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 24627416 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17299108 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 15189919 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27401338 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27401338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26826543 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16260426 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16260426 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9564799 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 9564799 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27012401 — Predictive Biomarker (PRD): IGF2R mRNA
Genes: IGF2R; MPRI
Study 27012401 — Surrogate Endpoint (SUR): Blood pressure
Study 21450569 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21450569 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2646301 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17361128 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 17361128 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 17361128 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17361128 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 17361128 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17361128 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 15375502 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 10204352 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 27932764 — Safety Biomarker (SAF): Cytochrome c
Study 7201271 — Surrogate Endpoint (SUR): Blood pressure
Study 29663701 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 18316629 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16273794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12610003 — Surrogate Endpoint (SUR): Blood pressure
Study 10480767 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 16049806 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 10394161 — Surrogate Endpoint (SUR): Blood pressure
Study 31647496 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9643529 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9643529 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7621303 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31584311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31584311 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24198887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24198887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27950663 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 1442657 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1442657 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1442657 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 3880685 — Surrogate Endpoint (SUR): Blood pressure
Study 26924051 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24271056 — Predictive Biomarker (PRD): Hormone receptor
Study 16266450 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 371021 — Surrogate Endpoint (SUR): Blood pressure
Study 31392790 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 19826291 — Surrogate Endpoint (SUR): Blood pressure
Study 16506871 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 11063279 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11063279 — Surrogate Endpoint (SUR): Blood pressure
Study 9115065 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1492231 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27244537 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16236917 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 11869857 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 28112773 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19515791 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 19515791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19515791 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10692976 — Surrogate Endpoint (SUR): Bone mineral density
Study 6996897 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18832244 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12847427 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 12847427 — Predictive Biomarker (PRD): CALM2 mRNA
Genes: CALM2; CAM2; CAMB
Study 17109866 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 21839850 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16858354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16858354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16858354 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15199384 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 3687315 — Safety Biomarker (SAF): Urinary total protein
Study 3687315 — Surrogate Endpoint (SUR): Blood pressure
Study 29363365 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10215313 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7533226 — Surrogate Endpoint (SUR): Blood pressure
Study 7533226 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31423576 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study 31423576 — Predictive Biomarker (PRD): MEF2B mRNA
Genes: MEF2B; XMEF2
Study 31423576 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31423576 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 31423576 — Predictive Biomarker (PRD): CREBBP mRNA
Genes: CREBBP; CBP
Study 31423576 — Predictive Biomarker (PRD): CARD11 mRNA
Genes: CARD11; CARMA1
Study 25706751 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25706751 — Surrogate Endpoint (SUR): Serum calcium
Study 19025521 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8826981 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 1590581 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 20444749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16274377 — Surrogate Endpoint (SUR): Blood pressure
Study 14697441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11214722 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11704128 — Predictive Biomarker (PRD): HCG22 mRNA
Genes: HCG22; G2; PBMUCL2
Study 9385564 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26742305 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 26742305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26742305 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21212367 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11989571 — Surrogate Endpoint (SUR): Serum creatinine
Study 11989571 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 26757748 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 26757748 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 10650325 — Surrogate Endpoint (SUR): Blood pressure
Study 9094066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8477064 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 18422771 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15969877 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 10845571 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 11343005 — Surrogate Endpoint (SUR): Blood pressure
Study 9273829 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 16759047 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31715306 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31715306 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31715306 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 31715306 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28699886 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28699886 — Safety Biomarker (SAF): Interleukin 1
Study 28699886 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 28699886 — Surrogate Endpoint (SUR): Serum calcium
Study 18172922 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 11740262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30942028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28426260 — Surrogate Endpoint (SUR): Blood pressure
Study 19491213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16967040 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17114190 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 10440120 — Surrogate Endpoint (SUR): Blood pressure
Study 9164416 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28412602 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 26781346 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24963611 — Surrogate Endpoint (SUR): Blood pressure
Study 22543063 — Predictive Biomarker (PRD): PER3 mRNA
Genes: PER3; GIG13
Study 20139790 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20139790 — Surrogate Endpoint (SUR): Blood pressure
Study 25824248 — Surrogate Endpoint (SUR): Blood pressure
Study 11465092 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11465092 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 11465092 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 11465092 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9486289 — Surrogate Endpoint (SUR): Blood pressure
Study 30632290 — Surrogate Endpoint (SUR): Bone mineral density
Study 28950268 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 28801400 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 23181712 — Surrogate Endpoint (SUR): Blood pressure
Study 16687084 — Surrogate Endpoint (SUR): Blood pressure
Study 3535986 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24760484 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 15877299 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15877299 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12746736 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11752035 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31596612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31596612 — Surrogate Endpoint (SUR): Serum creatinine
Study 9061991 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 7953415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7953415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31944487 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31944487 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 16321668 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30473540 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 30473540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10654875 — Surrogate Endpoint (SUR): Blood pressure
Study 7751412 — Surrogate Endpoint (SUR): Blood pressure
Study 30472215 — Predictive Biomarker (PRD): Hormone receptor
Study 29843644 — Surrogate Endpoint (SUR): Blood pressure
Study 18514630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7793203 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18580852 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 18580852 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 18580852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18580852 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18580852 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 18580852 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 21371282 — Surrogate Endpoint (SUR): Blood pressure
Study 19621985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16988754 — Surrogate Endpoint (SUR): Blood pressure
Study 10342818 — Surrogate Endpoint (SUR): Blood pressure
Study 8728305 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 8728305 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25098557 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 21900837 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15983826 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 11997270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11997270 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28682871 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28682871 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20709498 — Surrogate Endpoint (SUR): Blood pressure
Study 30668196 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 30668196 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 19103558 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15385732 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 15385732 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29352071 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 29352071 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27510532 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28822007 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 24227635 — Surrogate Endpoint (SUR): Blood pressure
Study 19523596 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 12730797 — Surrogate Endpoint (SUR): Bone mineral density
Study 1736933 — Surrogate Endpoint (SUR): Blood pressure