TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30290629 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11575418 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8060926 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30982860 — Predictive Biomarker (PRD): AMY1A mRNA
Genes: AMY1A; AMY1
Study 19401528 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12577389 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 25464237 — Surrogate Endpoint (SUR): Serum creatinine
Study 9250464 — Surrogate Endpoint (SUR): Blood pressure
Study 3711577 — Surrogate Endpoint (SUR): Blood pressure
Study 31377992 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28852205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30484683 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 22744970 — Surrogate Endpoint (SUR): Blood pressure
Study 9408064 — Surrogate Endpoint (SUR): Bone mineral density
Study 23867841 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23867841 — Surrogate Endpoint (SUR): Blood pressure
Study 23867841 — Surrogate Endpoint (SUR): Serum creatinine
Study 14644854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23570501 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 23570501 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23570501 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 19185642 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19185642 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19185642 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19185642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19185642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19185642 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17431226 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17133300 — Surrogate Endpoint (SUR): Blood pressure
Study 1904354 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 29471839 — Surrogate Endpoint (SUR): Blood pressure
Study 22956509 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 22956509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17934830 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10596994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1992363 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 17573745 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8507122 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8507122 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3034026 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3034026 — Surrogate Endpoint (SUR): Blood pressure
Study 25079863 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 18480672 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9371346 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3758141 — Surrogate Endpoint (SUR): Serum potassium
Study 3758141 — Surrogate Endpoint (SUR): Blood pressure
Study 31663690 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 20934440 — Surrogate Endpoint (SUR): Blood pressure
Study 16434463 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11306523 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2906248 — Surrogate Endpoint (SUR): Blood pressure
Study 30655188 — Surrogate Endpoint (SUR): Bone mineral density
Study 30232597 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23819122 — Surrogate Endpoint (SUR): Blood pressure
Study 19922034 — Surrogate Endpoint (SUR): Blood pressure
Study 19922034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19922034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19922034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19922034 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20628405 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 11166781 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11166781 — Surrogate Endpoint (SUR): Blood pressure
Study 7913970 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3061974 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3061974 — Surrogate Endpoint (SUR): Blood pressure
Study 29949232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27912901 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 15179410 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15179410 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 15179410 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15179410 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15179410 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12211668 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26505413 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 15192321 — Surrogate Endpoint (SUR): Blood pressure
Study 15192321 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 30047176 — Surrogate Endpoint (SUR): Blood pressure
Study 25322597 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21297492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21297492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21297492 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21297492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19076931 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8673544 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24500308 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 24500308 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19669013 — Surrogate Endpoint (SUR): Blood pressure
Study 15592273 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8196140 — Safety Biomarker (SAF): Interleukin 1
Study 30795802 — Predictive Biomarker (PRD): HTRA1 mRNA
Genes: HTRA1; HTRA; PRSS11
Study 18470666 — Surrogate Endpoint (SUR): Bone mineral density
Study 2683758 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2683758 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1089438 — Surrogate Endpoint (SUR): Blood pressure
Study 31177752 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31177752 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19857084 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19857084 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19857084 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 16707546 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26767384 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 18458698 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11004136 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 8968265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29691233 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 29691233 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 29691233 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26708636 — Surrogate Endpoint (SUR): Blood pressure
Study 15759292 — Surrogate Endpoint (SUR): Bacterial count
Study 30268481 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 10351969 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26337820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26337820 — Surrogate Endpoint (SUR): Blood pressure
Study 29520926 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 26948366 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 26948366 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 23734703 — Surrogate Endpoint (SUR): Blood pressure
Study 20416080 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20416080 — Surrogate Endpoint (SUR): Blood pressure
Study 8652950 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study 28130918 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 23766507 — Surrogate Endpoint (SUR): Blood pressure
Study 11354519 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29739677 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29739677 — Surrogate Endpoint (SUR): Blood pressure
Study 3310827 — Surrogate Endpoint (SUR): Blood pressure
Study 27042166 — Surrogate Endpoint (SUR): Blood pressure
Study 19086719 — Predictive Biomarker (PRD): ARX mRNA
Genes: ARX
Study 31117835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12575603 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18394829 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24534270 — Surrogate Endpoint (SUR): Blood pressure
Study 10919601 — Surrogate Endpoint (SUR): Serum creatinine
Study 24835503 — Predictive Biomarker (PRD): PLN mRNA
Genes: PLN; PLB
Study 28510573 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 23625101 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 20573162 — Surrogate Endpoint (SUR): Serum creatinine
Study 11512247 — Surrogate Endpoint (SUR): Blood pressure
Study 9766455 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 3046630 — Surrogate Endpoint (SUR): Blood pressure
Study 15248191 — Surrogate Endpoint (SUR): Blood pressure
Study 9710010 — Safety Biomarker (SAF): Hyaluronic acid
Study 2837895 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29415837 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16940442 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24925090 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 12485511 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 9802273 — Surrogate Endpoint (SUR): Blood pressure
Study 6335005 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30500110 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18338627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15847251 — Surrogate Endpoint (SUR): Blood pressure
Study 12774056 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10420392 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10420392 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30688377 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 14636905 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14636905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29641281 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27263311 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27263311 — Surrogate Endpoint (SUR): Blood pressure
Study 22765917 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 22765917 — Predictive Biomarker (PRD): CA3 mRNA
Genes: CA3
Study 1659172 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30554611 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30027496 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 21476945 — Surrogate Endpoint (SUR): Blood pressure
Study 17567421 — Surrogate Endpoint (SUR): Serum creatinine
Study 31826682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12964065 — Surrogate Endpoint (SUR): Bone mineral density
Study 3161013 — Surrogate Endpoint (SUR): Blood pressure
Study 25637044 — Surrogate Endpoint (SUR): Serum creatinine
Study 25637044 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22861074 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 2711992 — Surrogate Endpoint (SUR): Blood pressure
Study 25816713 — Surrogate Endpoint (SUR): Blood pressure
Study 20723985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26787360 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 21370966 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21370966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21370966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29878264 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 16150255 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30955977 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30955977 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 30955977 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 22035463 — Surrogate Endpoint (SUR): Blood pressure
Study 17211296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17211296 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14651394 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29800622 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 26691407 — Surrogate Endpoint (SUR): Blood pressure
Study 12898820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12898820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21161116 — Surrogate Endpoint (SUR): Blood pressure
Study 17763203 — Surrogate Endpoint (SUR): Blood pressure
Study 17763203 — Surrogate Endpoint (SUR): Serum creatinine
Study 17763203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15199080 — Surrogate Endpoint (SUR): Blood pressure
Study 7659480 — Safety Biomarker (SAF): Preexisting antibody
Study 2396471 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 93180 — Surrogate Endpoint (SUR): Blood pressure
Study 30138543 — Predictive Biomarker (PRD): GPRC6A mRNA
Genes: GPRC6A
Study 26969581 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 22463922 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22463922 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22463922 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20934557 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30143003 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 18254326 — Predictive Biomarker (PRD): PARPBP mRNA
Genes: PARPBP; C12orf48; PARI
Study 31557061 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 31557061 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 31557061 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31557061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28004395 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23486191 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23486191 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21857390 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 11120722 — Surrogate Endpoint (SUR): Blood pressure
Study 11120722 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 4033356 — Surrogate Endpoint (SUR): Blood pressure
Study 16166438 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21716273 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 21716273 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9729054 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26272736 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 23884013 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 16137016 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 9225173 — Surrogate Endpoint (SUR): Blood pressure
Study 16401468 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 15364856 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10087435 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 23254482 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 16505657 — Surrogate Endpoint (SUR): Serum creatinine
Study 26385214 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21651805 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 16780624 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8174528 — Surrogate Endpoint (SUR): Serum calcium
Study 25322274 — Surrogate Endpoint (SUR): Bone mineral density
Study 20653352 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20653352 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18977721 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31514562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31514562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31514562 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29616454 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29616454 — Surrogate Endpoint (SUR): Blood pressure
Study 23550669 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30856236 — Surrogate Endpoint (SUR): Blood pressure
Study 24180595 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24180595 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 20444958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15712083 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31512330 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21735653 — Predictive Biomarker (PRD): PLXNB1 mRNA
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 21735653 — Predictive Biomarker (PRD): SEPTIN6 mRNA
Genes: SEPTIN6; KIAA0128; SEP2; SEPT6
Study 19164187 — Surrogate Endpoint (SUR): Bone mineral density
Study 7018363 — Surrogate Endpoint (SUR): Blood pressure
Study 7018363 — Surrogate Endpoint (SUR): Serum potassium
Study 10076939 — Surrogate Endpoint (SUR): Bone mineral density
Study 19755697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19755697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9881389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9881389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1103213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23821088 — Surrogate Endpoint (SUR): Blood pressure
Study 20975012 — Surrogate Endpoint (SUR): Blood pressure
Study 12230618 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21038648 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31671276 — Surrogate Endpoint (SUR): Blood pressure
Study 25871304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23698211 — Predictive Biomarker (PRD): DSTN mRNA
Genes: DSTN; ACTDP; DSN
Study 11360574 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 11360574 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 24481828 — Predictive Biomarker (PRD): MAVS mRNA
Genes: MAVS; IPS1; KIAA1271; VISA
Study 18974704 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18974704 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18974704 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18974704 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16568436 — Predictive Biomarker (PRD): Liver iron