TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03433027 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02688569 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02474225 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02450942 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02450942 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02450942 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01521845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01954875 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03706326 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT00061750 — Predictive Biomarker (PRD): Liver iron
Study NCT02621385 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02963272 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT05304832 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04507074 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study NCT04507074 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04507074 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT04507074 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT04507074 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04507074 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study NCT04507074 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT04507074 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02376985 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00281229 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03789188 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01262352 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02576431 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT02576431 — Predictive Biomarker (PRD): NTRK2 mRNA
Genes: NTRK2; TRKB
Study NCT02576431 — Predictive Biomarker (PRD): NTRK3 mRNA
Genes: NTRK3; TRKC
Study NCT01724398 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05253781 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00450385 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT02420886 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02420886 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study NCT03497689 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04473573 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03501784 — Surrogate Endpoint (SUR): Bacterial count
Study NCT04804852 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT04201912 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study NCT04201912 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT04201912 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study NCT04520269 — Predictive Biomarker (PRD): IRAK1 mRNA
Genes: IRAK1; IRAK
Study NCT04520269 — Safety Biomarker (SAF): Interleukin 1
Study NCT04520269 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT01352585 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT02708511 — Predictive Biomarker (PRD): CA6 mRNA
Genes: CA6
Study NCT03334487 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study NCT01324245 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01324245 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01519726 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02355340 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02468661 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01377285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01377285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01377285 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01377285 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT00629486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03444025 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03444025 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00896519 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02978612 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study NCT02241681 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04372225 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01585389 — Predictive Biomarker (PRD): NEIL3 mRNA
Genes: NEIL3
Study NCT00893607 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03348514 — Predictive Biomarker (PRD): CPOX mRNA
Genes: CPOX; CPO; CPX
Study NCT01449825 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01449825 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03578406 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03578406 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03068390 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01560598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02182830 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01004081 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01004081 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00978354 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00978354 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT03637855 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03746262 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03786289 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00305825 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00815477 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00815477 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00161421 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00302692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00416403 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02811354 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02811354 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02811354 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT00140556 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00140556 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00140556 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00140556 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06346236 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04104542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT04104542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06136845 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT01121588 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02167217 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01718210 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04550663 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study NCT03894150 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT02179398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02179398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01685385 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04570410 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03170206 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00219180 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01106781 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04837391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02615301 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01607021 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT02410148 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01433523 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02558270 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02847533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02259231 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00567931 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT04412499 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03728244 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02589431 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study NCT02589431 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT03119649 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03975543 — Predictive Biomarker (PRD): PDE6B mRNA
Genes: PDE6B; PDEB
Study NCT04387656 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06339554 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01583439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00585091 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02639676 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04489420 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02278705 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00036374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03733145 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02628340 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT00319449 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03327688 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03481491 — Predictive Biomarker (PRD): ADCY5 mRNA
Genes: ADCY5
Study NCT03481491 — Predictive Biomarker (PRD): PRRT2 mRNA
Genes: PRRT2
Study NCT03423706 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03423706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT03423706 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00149175 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study NCT00149175 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study NCT00149175 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00674219 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02867800 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT02209779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03665155 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT00141583 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00141583 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00141583 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03636698 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study NCT03636698 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study NCT03636698 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT03636698 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04277195 — Predictive Biomarker (PRD): SPAG5 mRNA
Genes: SPAG5
Study NCT00708929 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study NCT01445054 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03051880 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03051880 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00042952 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT00155844 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT00155844 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT00114361 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02842814 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT03157557 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02054546 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT02682511 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05469087 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01264627 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00534417 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04424914 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05366608 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02693964 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02528695 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study NCT02924805 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02466529 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT01608191 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04553887 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02831530 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02831530 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00254397 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01980446 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT00394745 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01175889 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04137614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04152343 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study NCT02813538 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00377962 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01905215 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00672113 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00634270 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT04948086 — Safety Biomarker (SAF): MTHFR
Study NCT00608465 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01663077 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01663077 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01663077 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT01663077 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00001427 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02132741 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04405206 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study NCT03280537 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT01671384 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT01671384 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT04823000 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02323360 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT02280083 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01614457 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00283829 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01380899 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT03876522 — Predictive Biomarker (PRD): ZFYVE9 mRNA
Genes: ZFYVE9; MADHIP; SARA; SMADIP
Study NCT04089098 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT02308111 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT03583463 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03583463 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03583463 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03583463 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00121407 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04576338 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02296879 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02296879 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT03410043 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01836315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01836315 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT00421447 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03185598 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00728338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03331211 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT01983098 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01983098 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04723836 — Safety Biomarker (SAF): MTHFR
Study NCT04723836 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00783289 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT04665193 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01960686 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03177252 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00881920 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT03150121 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03131999 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT00368368 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study NCT01815567 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01903759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00106977 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT00106977 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT00460356 — Predictive Biomarker (PRD): MAPK8IP2 mRNA
Genes: MAPK8IP2; IB2; JIP2; PRKM8IPL
Study NCT03885466 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01978366 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01789918 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04331197 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00410566 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study NCT00170924 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03195296 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02218177 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00801671 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01578499 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00793923 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04595955 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04595955 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03707093 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT03580057 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03842709 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT03842709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03842709 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT03842709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT00756964 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02628769 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT02628769 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT04975048 — Predictive Biomarker (PRD): SREBF1 mRNA
Genes: SREBF1; BHLHD1; SREBP1