TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15307695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11780351 — Surrogate Endpoint (SUR): Blood pressure
Study 9280714 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9280714 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 9280714 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 2883575 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31231923 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 21632472 — Surrogate Endpoint (SUR): Serum uric acid
Study 21632472 — Surrogate Endpoint (SUR): Serum creatinine
Study 9450156 — Surrogate Endpoint (SUR): Blood pressure
Study 28671856 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28671856 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16837736 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8093139 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16469980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31805386 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31805386 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31805386 — Surrogate Endpoint (SUR): Bone mineral density
Study 28185713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28185713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14676595 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25452300 — Surrogate Endpoint (SUR): Blood pressure
Study 14656250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31205187 — Predictive Biomarker (PRD): PDE10A mRNA
Genes: PDE10A
Study 28593920 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28593920 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 28593920 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 9081352 — Surrogate Endpoint (SUR): Serum sodium
Study 18046048 — Surrogate Endpoint (SUR): Serum testosterone
Study 18046048 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 18046048 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17057417 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10746815 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1614074 — Surrogate Endpoint (SUR): Blood pressure
Study 12939889 — Surrogate Endpoint (SUR): Blood pressure
Study 6134137 — Surrogate Endpoint (SUR): Serum potassium
Study 6134137 — Surrogate Endpoint (SUR): Blood pressure
Study 24768191 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24768191 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 24768191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16187006 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11696738 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25833957 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 19167733 — Surrogate Endpoint (SUR): Serum testosterone
Study 11248742 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 27978867 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19894330 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 15100375 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24955642 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 24955642 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 22499290 — Surrogate Endpoint (SUR): Blood pressure
Study 17620073 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 22520631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17588396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17588396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17588396 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 17588396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17588396 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17588396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11454380 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30607545 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29212812 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23261355 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9068934 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 8103648 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16234451 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 10459902 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 31759193 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 12784383 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 12784383 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12784383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18023335 — Surrogate Endpoint (SUR): Serum potassium
Study 18023335 — Surrogate Endpoint (SUR): Blood pressure
Study 9079233 — Surrogate Endpoint (SUR): Blood pressure
Study 3717956 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 7969280 — Surrogate Endpoint (SUR): Serum creatinine
Study 26190830 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 22120765 — Surrogate Endpoint (SUR): Blood pressure
Study 12187023 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8697717 — Surrogate Endpoint (SUR): Blood pressure
Study 22819265 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 10726112 — Surrogate Endpoint (SUR): Blood pressure
Study 10726112 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23799706 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21836369 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 21836369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10690135 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26926372 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 24570273 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 24570273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24570273 — Surrogate Endpoint (SUR): Blood pressure
Study 24570273 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15060416 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15060416 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9827406 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29417832 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23715755 — Surrogate Endpoint (SUR): Blood pressure
Study 10674226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10674226 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8369008 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31948296 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31948296 — Safety Biomarker (SAF): BDNF
Study 24974387 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20673378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20673378 — Surrogate Endpoint (SUR): Blood pressure
Study 12392587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19049703 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 19049703 — Surrogate Endpoint (SUR): Serum creatinine
Study 10889804 — Surrogate Endpoint (SUR): Blood pressure
Study 10889804 — Surrogate Endpoint (SUR): Serum triglycerides
Study 1467514 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 26849844 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 25391194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12940609 — Surrogate Endpoint (SUR): Serum creatinine
Study 6507426 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6507426 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25913873 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 11110418 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1922908 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1922908 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24669014 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 27990643 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23343964 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 23343964 — Surrogate Endpoint (SUR): Blood pressure
Study 18786982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18786982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18786982 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 187356 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 21646616 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21646616 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21646616 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21646616 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19351734 — Surrogate Endpoint (SUR): Bone mineral density
Study 12875313 — Surrogate Endpoint (SUR): Blood pressure
Study 8960814 — Surrogate Endpoint (SUR): Blood pressure
Study 14870956 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27870567 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27250730 — Surrogate Endpoint (SUR): Blood pressure
Study 6211981 — Surrogate Endpoint (SUR): Serum potassium
Study 6211981 — Surrogate Endpoint (SUR): Serum creatinine
Study 2669553 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31408377 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 31408377 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 14558954 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29377462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22222208 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 7690082 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7690082 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 7690082 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 7690082 — Surrogate Endpoint (SUR): Blood pressure
Study 18512141 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29956827 — Monitoring Biomarker (MOI): HBV DNA
Study 26762838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25384473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17885551 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2189951 — Surrogate Endpoint (SUR): Bone mineral density
Study 30706508 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 17409404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29759104 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 16084762 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9636847 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21288144 — Surrogate Endpoint (SUR): Blood pressure
Study 11165203 — Surrogate Endpoint (SUR): Blood pressure
Study 3007605 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3007605 — Surrogate Endpoint (SUR): Blood pressure
Study 30545333 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8091384 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9212965 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31752829 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 31752829 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21269547 — Predictive Biomarker (PRD): EPHA1 mRNA
Genes: EPHA1; EPH; EPHT; EPHT1
Study 16952781 — Safety Biomarker (SAF): Reactive oxygen species
Study 16952781 — Surrogate Endpoint (SUR): Serum uric acid
Study 11149473 — Surrogate Endpoint (SUR): Bone mineral density
Study 11149473 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 3119786 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6431573 — Surrogate Endpoint (SUR): Blood pressure
Study 6431573 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30887937 — Surrogate Endpoint (SUR): Blood pressure
Study 30887937 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30086659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30086659 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 30086659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22785573 — Surrogate Endpoint (SUR): Blood pressure
Study 16979991 — Surrogate Endpoint (SUR): Serum creatinine
Study 8894145 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 25234206 — Surrogate Endpoint (SUR): Blood pressure
Study 2874821 — Surrogate Endpoint (SUR): Blood pressure
Study 29774642 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 26614823 — Predictive Biomarker (PRD): IGF2R mRNA
Genes: IGF2R; MPRI
Study 12682480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12682480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12682480 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 12682480 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12682480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16873699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16873699 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 16873699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12623959 — Surrogate Endpoint (SUR): Blood pressure
Study 10519687 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 23588557 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 10809861 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24858158 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19848198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19848198 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17854429 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 27370396 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 21272325 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 21272325 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19561152 — Surrogate Endpoint (SUR): Blood pressure
Study 8050452 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 8050452 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8050452 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 8050452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8050452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25847934 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15611216 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 8017464 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23936377 — Surrogate Endpoint (SUR): Blood pressure
Study 23936377 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23936377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22044858 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22044858 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 16939848 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 9611062 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15103312 — Surrogate Endpoint (SUR): Blood pressure
Study 19585395 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17762658 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 17762658 — Surrogate Endpoint (SUR): Blood pressure
Study 1895978 — Surrogate Endpoint (SUR): Serum creatinine
Study 9087160 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3842544 — Surrogate Endpoint (SUR): Blood pressure
Study 30706571 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 30706571 — Predictive Biomarker (PRD): TOMM40 mRNA
Genes: TOMM40; C19orf1; PEREC1; TOM40
Study 30706571 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30706571 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 30706571 — Predictive Biomarker (PRD): SORL1 mRNA
Genes: SORL1; C11orf32
Study 24738835 — Monitoring Biomarker (MOI): HBV DNA
Study 19640359 — Surrogate Endpoint (SUR): Blood pressure
Study 2893778 — Surrogate Endpoint (SUR): Blood pressure
Study 28387058 — Surrogate Endpoint (SUR): Blood pressure
Study 18230798 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 14684712 — Surrogate Endpoint (SUR): Blood pressure
Study 31838405 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30624371 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 24457276 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 7826904 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28641838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15961759 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 19371522 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24275838 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24275838 — Surrogate Endpoint (SUR): Blood pressure
Study 18280619 — Predictive Biomarker (PRD): EHF mRNA
Genes: EHF; ESE3; ESE3B; ESEJ
Study 15902987 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15902987 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 1691367 — Surrogate Endpoint (SUR): Blood pressure
Study 25455437 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23636153 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 10809268 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 1317343 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29465549 — Surrogate Endpoint (SUR): Blood pressure
Study 7846539 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 30580454 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30580454 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30580454 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30580454 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 30580454 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 29083936 — Surrogate Endpoint (SUR): Serum potassium
Study 27538188 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18391460 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 10546920 — Surrogate Endpoint (SUR): Blood pressure
Study 1711261 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 6406947 — Surrogate Endpoint (SUR): Blood pressure
Study 29191561 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18670195 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17451570 — Surrogate Endpoint (SUR): Bone mineral density
Study 9678528 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9678528 — Surrogate Endpoint (SUR): Bone mineral density