TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16037885 — Predictive Biomarker (PRD): CKM mRNA
Genes: CKM; CKMM
Study 12388959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12388959 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 6127906 — Surrogate Endpoint (SUR): Blood pressure
Study 30929268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30929268 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29202751 — Surrogate Endpoint (SUR): Blood pressure
Study 29202751 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21167906 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19880052 — Surrogate Endpoint (SUR): Bone mineral density
Study 16111901 — Surrogate Endpoint (SUR): Blood pressure
Study 24213955 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24213955 — Safety Biomarker (SAF): BDNF
Study 2188845 — Surrogate Endpoint (SUR): Serum potassium
Study 2188845 — Surrogate Endpoint (SUR): Blood pressure
Study 17013645 — Surrogate Endpoint (SUR): Bone mineral density
Study 9701528 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30695420 — Surrogate Endpoint (SUR): Serum creatinine
Study 26089547 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 21624541 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 19364997 — Surrogate Endpoint (SUR): Blood pressure
Study 11406520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11406520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11406520 — Safety Biomarker (SAF): Interleukin 1
Study 2974095 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2974095 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2974095 — Surrogate Endpoint (SUR): Blood pressure
Study 22381025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22381025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18046109 — Surrogate Endpoint (SUR): Blood pressure
Study 15272291 — Surrogate Endpoint (SUR): Blood pressure
Study 7597608 — Surrogate Endpoint (SUR): Serum sodium
Study 30987164 — Safety Biomarker (SAF): miR-423
Genes: MIR423
Study 30987164 — Safety Biomarker (SAF): let-7a
Study 30987164 — Monitoring Biomarker (MOI): miR-26a
Study 11867933 — Surrogate Endpoint (SUR): Bone mineral density
Study 11867933 — Surrogate Endpoint (SUR): Serum calcium
Study 11867933 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 6772045 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23660512 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23660512 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16801586 — Surrogate Endpoint (SUR): Blood pressure
Study 12756090 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8103820 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14618470 — Surrogate Endpoint (SUR): Bone mineral density
Study 26519996 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10325501 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10325501 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 1422748 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 15642073 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10082501 — Surrogate Endpoint (SUR): Blood pressure
Study 7579751 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 22389220 — Surrogate Endpoint (SUR): Blood pressure
Study 15159307 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 15159307 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 12428241 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9839295 — Surrogate Endpoint (SUR): Blood pressure
Study 30326045 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12578880 — Surrogate Endpoint (SUR): Blood pressure
Study 10386412 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10386412 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21332346 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 11521964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11521964 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21534836 — Surrogate Endpoint (SUR): Blood pressure
Study 19559166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26842950 — Safety Biomarker (SAF): Interleukin 1
Study 21907450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21907450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18184542 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18184542 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18184542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18184542 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18184542 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11530030 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31980978 — Surrogate Endpoint (SUR): Serum uric acid
Study 30219400 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 17138219 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 12753370 — Surrogate Endpoint (SUR): Probing pocket depth
Study 28303753 — Surrogate Endpoint (SUR): Bone mineral density
Study 25085943 — Surrogate Endpoint (SUR): Blood pressure
Study 18422837 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 18422837 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 18422837 — Safety Biomarker (SAF): Hyaluronic acid
Study 12559133 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17700386 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 10503666 — Safety Biomarker (SAF): Hyaluronic acid
Study 26580123 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 10397695 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10397695 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2202458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23642776 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23642776 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21276616 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 19995648 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19995648 — Predictive Biomarker (PRD): Hormone receptor
Study 19995648 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1406416 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31748169 — Surrogate Endpoint (SUR): Blood pressure
Study 24398943 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 12517681 — Surrogate Endpoint (SUR): Blood pressure
Study 30939472 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 30939472 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 30939472 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 27943617 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 27943617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27943617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9862770 — Surrogate Endpoint (SUR): Blood pressure
Study 30141776 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 21426884 — Safety Biomarker (SAF): Reactive oxygen species
Study 21426884 — Surrogate Endpoint (SUR): Serum creatinine
Study 21426884 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18411913 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 27928115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27928115 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 19347813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 12050268 — Surrogate Endpoint (SUR): Bone mineral density
Study 10968690 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23238930 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 23238930 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 25495610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25495610 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17914031 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7944428 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 29919984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29919984 — Surrogate Endpoint (SUR): Serum creatinine
Study 7988260 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 30060100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23866813 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19673328 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 8912742 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study 15802770 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8784330 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31209191 — Surrogate Endpoint (SUR): Serum creatinine
Study 27889832 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27889832 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23656463 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19622007 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17597499 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17597499 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8483018 — Surrogate Endpoint (SUR): Blood pressure
Study 8483018 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24829497 — Surrogate Endpoint (SUR): Blood pressure
Study 23842679 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 23842679 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 3113778 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 28605158 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 26426277 — Surrogate Endpoint (SUR): Blood pressure
Study 8239200 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27645318 — Predictive Biomarker (PRD): XG mRNA
Genes: XG; PBDX
Study 27645318 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 25307414 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 20668444 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20668444 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10365287 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15134183 — Surrogate Endpoint (SUR): Serum creatinine
Study 3353874 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11464618 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20398258 — Surrogate Endpoint (SUR): Blood pressure
Study 12003160 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9797978 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 29231496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 29231496 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8916815 — Surrogate Endpoint (SUR): Blood pressure
Study 12221462 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 24048291 — Surrogate Endpoint (SUR): Blood pressure
Study 20876406 — Surrogate Endpoint (SUR): Bone mineral density
Study 30651324 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 22694918 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 21127898 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21127898 — Surrogate Endpoint (SUR): Blood pressure
Study 15500630 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 24255934 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18230968 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 28321995 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25795452 — Surrogate Endpoint (SUR): Blood pressure
Study 23442248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24391142 — Surrogate Endpoint (SUR): Blood pressure
Study 18511473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18511473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12699514 — Predictive Biomarker (PRD): MMP12 mRNA
Genes: MMP12; HME
Study 1430283 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21900640 — Surrogate Endpoint (SUR): Blood pressure
Study 19491910 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 3300967 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study 24934544 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 9733448 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9733448 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9733448 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9733448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30032842 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 30032842 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 30032842 — Predictive Biomarker (PRD): PDGFD mRNA
Genes: PDGFD; IEGF; SCDGFB; MSTP036; UNQ1899/PRO4345
Study 30032842 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 24770930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24770930 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17638141 — Surrogate Endpoint (SUR): Blood pressure
Study 11332356 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 29080069 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29080069 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9385891 — Surrogate Endpoint (SUR): Blood pressure
Study 20932157 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 19535691 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16926245 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11701677 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8185744 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10831641 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2857901 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1894296 — Surrogate Endpoint (SUR): Blood pressure
Study 24120264 — Surrogate Endpoint (SUR): Blood pressure
Study 22260859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28920458 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28920458 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10212103 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8729126 — Safety Biomarker (SAF): Interleukin 1
Study 8729126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1422714 — Surrogate Endpoint (SUR): Blood pressure
Study 4046122 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30140328 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 22142823 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 20549832 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16206600 — Surrogate Endpoint (SUR): Blood pressure
Study 30168611 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19814804 — Predictive Biomarker (PRD): EPHX2 mRNA
Genes: EPHX2
Study 24456422 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 24456422 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 16310197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 24085401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24085401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17785930 — Surrogate Endpoint (SUR): Serum creatinine
Study 17785930 — Surrogate Endpoint (SUR): Blood pressure
Study 17785930 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11178767 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11178767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9710029 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 7526676 — Surrogate Endpoint (SUR): Blood pressure
Study 21751904 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16912265 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16225723 — Surrogate Endpoint (SUR): Blood pressure
Study 23706899 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 19191743 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 19191743 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28437263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25675222 — Safety Biomarker (SAF): Hyaluronic acid
Study 16828500 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 16828500 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15342284 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15342284 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9603290 — Surrogate Endpoint (SUR): Blood pressure
Study 29384722 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18785409 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9625104 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 21606213 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27992435 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 22538805 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 15630195 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 3120587 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3120587 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3120587 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31671938 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 21859323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21859323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17389710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17389710 — Surrogate Endpoint (SUR): Blood pressure
Study 6259250 — Surrogate Endpoint (SUR): Blood pressure
Study 15489491 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 30508196 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28478132 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 16697494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16697494 — Safety Biomarker (SAF): Reactive oxygen species
Study 15477632 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 15477632 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 8970755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8970755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28089476 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD