TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25963221 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24240384 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 24240384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24240384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11903396 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30997631 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23075258 — Predictive Biomarker (PRD): SLC35G1 mRNA
Genes: SLC35G1; C10orf60; POST; TMEM20
Study 11369630 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11344383 — Surrogate Endpoint (SUR): Serum creatinine
Study 7915235 — Surrogate Endpoint (SUR): Blood pressure
Study 16595611 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8101532 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25154739 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 24192015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24192015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24192015 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24192015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21166767 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 17145606 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 24995559 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 24995559 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 24995559 — Predictive Biomarker (PRD): MBOAT4 mRNA
Genes: MBOAT4; GOAT; OACT4; FKSG89
Study 12427411 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12427411 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1871184 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 1871184 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 31425171 — Surrogate Endpoint (SUR): Blood pressure
Study 24314863 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 24314863 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24314863 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 16400891 — Surrogate Endpoint (SUR): Serum potassium
Study 8573426 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 25295709 — Monitoring Biomarker (MOI): Procalcitonin
Study 20799286 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 7698053 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7698053 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7698053 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27831503 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 18851956 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 18851956 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study 18851956 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18851956 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 17518508 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29225152 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20141367 — Surrogate Endpoint (SUR): Bone mineral density
Study 17042906 — Surrogate Endpoint (SUR): Serum testosterone
Study 2877490 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 26927315 — Surrogate Endpoint (SUR): Blood pressure
Study 18587135 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18587135 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31987229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31987229 — Surrogate Endpoint (SUR): Blood pressure
Study 31987229 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11408428 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 11408428 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31229619 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 31229619 — Predictive Biomarker (PRD): PTPRN mRNA
Genes: PTPRN; ICA3; ICA512
Study 23243173 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 16673803 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 9761513 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9761513 — Surrogate Endpoint (SUR): Serum calcium
Study 7800969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28532870 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 23315099 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23315099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15087630 — Surrogate Endpoint (SUR): Blood pressure
Study 11702034 — Surrogate Endpoint (SUR): Blood pressure
Study 7934143 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7934143 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 7934143 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 15960643 — Surrogate Endpoint (SUR): Blood pressure
Study 8844478 — Monitoring Biomarker (MOI): HBV DNA
Study 31372804 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31372804 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 12452075 — Surrogate Endpoint (SUR): Blood pressure
Study 29637543 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 29637543 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 11965505 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8345000 — Surrogate Endpoint (SUR): Serum creatinine
Study 26995376 — Surrogate Endpoint (SUR): Blood pressure
Study 17711927 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15190052 — Surrogate Endpoint (SUR): Blood pressure
Study 15190052 — Surrogate Endpoint (SUR): Serum potassium
Study 12200215 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 2477338 — Surrogate Endpoint (SUR): Serum potassium
Study 334435 — Surrogate Endpoint (SUR): Blood pressure
Study 26848624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25239582 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20371660 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20371660 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10384248 — Surrogate Endpoint (SUR): Blood pressure
Study 26214438 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 23563560 — Surrogate Endpoint (SUR): Blood pressure
Study 18317438 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16570047 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16570047 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16570047 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 12649101 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10874052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10874052 — Surrogate Endpoint (SUR): Serum creatinine
Study 9288186 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 22946099 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 22946099 — Surrogate Endpoint (SUR): Blood pressure
Study 19225067 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15161783 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 15161783 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11309650 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30296402 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15483079 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28296139 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9197430 — Surrogate Endpoint (SUR): Blood pressure
Study 20977356 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11812667 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 10075615 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 10075615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2201047 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31220872 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 24389434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28635082 — Surrogate Endpoint (SUR): Blood pressure
Study 22051148 — Predictive Biomarker (PRD): FFAR1 mRNA
Genes: FFAR1; GPR40
Study 22051148 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12859697 — Surrogate Endpoint (SUR): Bone mineral density
Study 1324555 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 6401927 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24373063 — Surrogate Endpoint (SUR): Blood pressure
Study 19622714 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9657538 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9657538 — Surrogate Endpoint (SUR): Blood pressure
Study 2690898 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 15383187 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15383187 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8091167 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 1130178 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 19015207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11699053 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 11699053 — Surrogate Endpoint (SUR): Serum calcium
Study 23257173 — Surrogate Endpoint (SUR): Blood pressure
Study 23257173 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27456837 — Surrogate Endpoint (SUR): Blood pressure
Study 20190331 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 27787467 — Surrogate Endpoint (SUR): Blood pressure
Study 24219758 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 9105060 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9105060 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26508659 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 15126928 — Surrogate Endpoint (SUR): Blood pressure
Study 30124597 — Safety Biomarker (SAF): Human leucocyte antigen
Study 27855541 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 24722498 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 31526874 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 28278194 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 22133239 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 20079223 — Surrogate Endpoint (SUR): Blood pressure
Study 16395076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16395076 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 1309865 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 6331037 — Surrogate Endpoint (SUR): Blood pressure
Study 18344081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18344081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14555566 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10700888 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27655166 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19930408 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18077495 — Predictive Biomarker (PRD): FTL mRNA
Genes: FTL
Study 10717327 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 30942842 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16825290 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16825290 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16825290 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16825290 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9286849 — Surrogate Endpoint (SUR): Blood pressure
Study 8269656 — Surrogate Endpoint (SUR): Blood pressure
Study 22677192 — Surrogate Endpoint (SUR): Blood pressure
Study 14585084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2121325 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2121325 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 619947 — Surrogate Endpoint (SUR): Blood pressure
Study 16733228 — Safety Biomarker (SAF): Reactive oxygen species
Study 16733228 — Surrogate Endpoint (SUR): Blood pressure
Study 29878225 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29878225 — Predictive Biomarker (PRD): Hormone receptor
Study 17542110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9360031 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 1551298 — Surrogate Endpoint (SUR): Blood pressure
Study 30202851 — Surrogate Endpoint (SUR): Blood pressure
Study 30202851 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30202851 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24811940 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 11352774 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 11352774 — Surrogate Endpoint (SUR): Blood pressure
Study 30616601 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 1477191 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30675515 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30675515 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30675515 — Predictive Biomarker (PRD): Hormone receptor
Study 24603217 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22066819 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 17296645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22089205 — Surrogate Endpoint (SUR): Blood pressure
Study 11990442 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 23864112 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 23864112 — Surrogate Endpoint (SUR): Blood pressure
Study 17397949 — Surrogate Endpoint (SUR): Blood pressure
Study 12807346 — Surrogate Endpoint (SUR): Blood pressure
Study 11277825 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9551417 — Surrogate Endpoint (SUR): Blood pressure
Study 31531547 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 19939894 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 19939894 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 9257757 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30790377 — Surrogate Endpoint (SUR): Blood pressure
Study 21565464 — Surrogate Endpoint (SUR): Blood pressure
Study 8998184 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 19289342 — Surrogate Endpoint (SUR): Blood pressure
Study 16687712 — Surrogate Endpoint (SUR): Bone mineral density
Study 9433148 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 17306648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17306648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15105403 — Surrogate Endpoint (SUR): Bone mineral density
Study 31416496 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 19349712 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 14767865 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 14767865 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 29231566 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 29231566 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 22735756 — Predictive Biomarker (PRD): GRPR mRNA
Genes: GRPR
Study 22735756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2243428 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27585777 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 22639400 — Surrogate Endpoint (SUR): Bone mineral density
Study 12585164 — Surrogate Endpoint (SUR): Blood pressure
Study 10506719 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17240472 — Surrogate Endpoint (SUR): Blood pressure
Study 15616203 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9708408 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31868550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11430779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2663239 — Surrogate Endpoint (SUR): Blood pressure
Study 19114908 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7950723 — Surrogate Endpoint (SUR): Blood pressure
Study 30927057 — Surrogate Endpoint (SUR): Blood pressure
Study 16494569 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 10998313 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26338825 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20219096 — Surrogate Endpoint (SUR): Blood pressure
Study 775358 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 30569507 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 26700738 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 26700738 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 26700738 — Predictive Biomarker (PRD): IFNL3
Genes: IL-28B; IL28C
Study 19950567 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15238825 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 15238825 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9135948 — Surrogate Endpoint (SUR): Blood pressure
Study 23475780 — Surrogate Endpoint (SUR): Serum creatinine
Study 17112296 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 17112296 — Surrogate Endpoint (SUR): Blood pressure
Study 11327628 — Surrogate Endpoint (SUR): Blood pressure
Study 16177595 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 23114140 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19344229 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19344229 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19344229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14980754 — Surrogate Endpoint (SUR): Blood pressure
Study 8583478 — Surrogate Endpoint (SUR): Blood pressure
Study 8817406 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15847730 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2200257 — Surrogate Endpoint (SUR): Blood pressure
Study 2200257 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24366930 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 19755327 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 10528036 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25812529 — Safety Biomarker (SAF): Hyaluronic acid
Study 11214780 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8894790 — Surrogate Endpoint (SUR): Blood pressure
Study 8894790 — Surrogate Endpoint (SUR): Serum calcium
Study 20617456 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20617456 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20617456 — Surrogate Endpoint (SUR): Blood pressure
Study 15846111 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 10443063 — Surrogate Endpoint (SUR): Blood pressure
Study 22926324 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22926324 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11598430 — Surrogate Endpoint (SUR): Blood pressure
Study 8018525 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28482639 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24012146 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10634404 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 1312556 — Surrogate Endpoint (SUR): Blood pressure
Study 15188106 — Surrogate Endpoint (SUR): Bone mineral density
Study 1195474 — Surrogate Endpoint (SUR): Bacterial count
Study 22539562 — Predictive Biomarker (PRD): GCG mRNA
Genes: GCG
Study 11874412 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 1827005 — Surrogate Endpoint (SUR): Blood pressure
Study 1827005 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol