TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30158974 — Predictive Biomarker (PRD): MYCL mRNA
Genes: MYCL; BHLHE38; LMYC; MYCL1
Study 30158974 — Predictive Biomarker (PRD): PLIN1 mRNA
Genes: PLIN1; PERI; PLIN
Study 30161147 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30165570 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 30165570 — Surrogate Endpoint (SUR): Serum creatinine
Study 30165570 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30165599 — Surrogate Endpoint (SUR): Blood pressure
Study 30166291 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 30167089 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30167310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30167310 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 30167329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30167756 — Predictive Biomarker (PRD): SLC15A2 mRNA
Genes: SLC15A2; PEPT2
Study 30167756 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 30167756 — Predictive Biomarker (PRD): SLC22A3 mRNA
Genes: SLC22A3; EMTH; OCT3
Study 30168134 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 30169182 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 30169223 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30170630 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 30171081 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 30171081 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30171354 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30171779 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 30171779 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30172032 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 30172345 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 30173210 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 30174861 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30174890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30174920 — Surrogate Endpoint (SUR): Blood pressure
Study 30176673 — Surrogate Endpoint (SUR): Blood pressure
Study 30176673 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30176673 — Surrogate Endpoint (SUR): Serum potassium
Study 30177021 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 30178481 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30178481 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 30178481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30178528 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30180887 — Surrogate Endpoint (SUR): Serum creatinine
Study 30180944 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 30180944 — Predictive Biomarker (PRD): HCST mRNA
Genes: HCST; DAP10; KAP10; PIK3AP; UNQ587/PRO1157
Study 30180944 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30181172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30181415 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 30185213 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 30186623 — Surrogate Endpoint (SUR): Blood pressure
Study 30187599 — Monitoring Biomarker (MOI): HBV DNA
Study 30189049 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30190005 — Surrogate Endpoint (SUR): Blood pressure
Study 30190271 — Safety Biomarker (SAF): Th2 cell
Study 30190299 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30190299 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30190302 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30191097 — Surrogate Endpoint (SUR): Blood pressure
Study 30191465 — Surrogate Endpoint (SUR): Bone mineral density
Study 30191464 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30191523 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30192949 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30193554 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30193554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30195193 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30197098 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 30197280 — Predictive Biomarker (PRD): Microsatellite instability
Study 30197287 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 30198055 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 30198325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30198934 — Surrogate Endpoint (SUR): Blood pressure
Study 30199593 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30201848 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 30202211 — Surrogate Endpoint (SUR): Blood pressure
Study 30203445 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30203445 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 30203445 — Predictive Biomarker (PRD): ATG5 mRNA
Genes: ATG5; APG5L; ASP
Study 30203445 — Predictive Biomarker (PRD): FADD mRNA
Genes: FADD; MORT1; GIG3
Study 30203445 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30203580 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30204247 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 30205231 — Predictive Biomarker (PRD): NRM mRNA
Genes: NRM; NRM29; UNQ555/PRO1112
Study 30208871 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 30208971 — Predictive Biomarker (PRD): ABCA4 mRNA
Genes: ABCA4; ABCR
Study 30209610 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 30212850 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30213276 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 30213581 — Predictive Biomarker (PRD): COL3A1 mRNA
Genes: COL3A1
Study 30213581 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 30215671 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30215671 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30215671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30215671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30217228 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 30217377 — Surrogate Endpoint (SUR): Blood pressure
Study 30217671 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 30218977 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 30219500 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 30219915 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30220708 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study 30220708 — Predictive Biomarker (PRD): TACC3 mRNA
Genes: TACC3; ERIC1
Study 30221011 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30221150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30225601 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 30225949 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 30225949 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 30225949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30226851 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30226851 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30226851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30227886 — Predictive Biomarker (PRD): NLRC4 mRNA
Genes: NLRC4; CARD12; CLAN; CLAN1; IPAF; UNQ6189/PRO20215
Study 30227886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 30227886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 30227886 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 30227886 — Predictive Biomarker (PRD): GADD45A mRNA
Genes: GADD45A; DDIT1; GADD45
Study 30227886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 30227886 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 30227886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30227886 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 30227893 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 30227893 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 30228248 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30228251 — Surrogate Endpoint (SUR): Blood pressure
Study 30229280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30230947 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30231923 — Surrogate Endpoint (SUR): Blood pressure
Study 30232146 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 30232224 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 30233802 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30233812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30233812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30236025 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 30236390 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30236749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30239831 — Predictive Biomarker (PRD): AKAP13 mRNA
Genes: AKAP13; BRX; HT31; LBC
Study 30240327 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30240327 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 30240401 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 30240401 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30240401 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 30240401 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 30240471 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 30240852 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30241526 — Predictive Biomarker (PRD): COL1A2 mRNA
Genes: COL1A2
Study 30241526 — Predictive Biomarker (PRD): BGN mRNA
Genes: BGN; SLRR1A
Study 30241550 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 30241550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30242790 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30242831 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 30243817 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30245189 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 30245189 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 30246149 — Surrogate Endpoint (SUR): Blood pressure
Study 30246613 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 30247434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30253804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30253804 — Predictive Biomarker (PRD): TNFRSF18 mRNA
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study 30254130 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 30254130 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 30254130 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 30254761 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 30255862 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30256767 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30256893 — Predictive Biomarker (PRD): BCO2 mRNA
Genes: BCO2; BCDO2
Study 30258647 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30258647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30258647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30260393 — Predictive Biomarker (PRD): ACSL1 mRNA
Genes: ACSL1; FACL1; FACL2; LACS; LACS1; LACS2
Study 30260393 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 30260393 — Predictive Biomarker (PRD): FTL mRNA
Genes: FTL
Study 30260393 — Predictive Biomarker (PRD): SREBF1 mRNA
Genes: SREBF1; BHLHD1; SREBP1
Study 30260393 — Predictive Biomarker (PRD): DGAT2 mRNA
Genes: DGAT2; HMFN1045; UNQ738/PRO1433
Study 30260393 — Predictive Biomarker (PRD): SLC40A1 mRNA
Genes: SLC40A1; FPN; FPN1; IREG1; SLC11A3; MSTP079
Study 30260393 — Predictive Biomarker (PRD): HEPH mRNA
Genes: HEPH; KIAA0698; UNQ2562/PRO6242
Study 30261303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30261902 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30261899 — Predictive Biomarker (PRD): IL2RG mRNA
Genes: IL2RG
Study 30264864 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30264864 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 30265304 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 30268483 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30268483 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 30268483 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 30268483 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30268483 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30269918 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 30271433 — Surrogate Endpoint (SUR): Blood pressure
Study 30273708 — Surrogate Endpoint (SUR): Blood pressure
Study 30274985 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 30277089 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 30277089 — Predictive Biomarker (PRD): IKZF3 mRNA
Genes: IKZF3; ZNFN1A3
Study 30277089 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study 30278378 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30279111 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30279111 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30279111 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 30279111 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 30279111 — Monitoring Biomarker (MOI): Cell-free DNA
Study 30279125 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 30279583 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30280905 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30280906 — Surrogate Endpoint (SUR): Bone mineral density
Study 30282468 — Surrogate Endpoint (SUR): Blood pressure
Study 30282640 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 30282826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 30283029 — Surrogate Endpoint (SUR): Blood pressure
Study 30286724 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 30286776 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 30286821 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30287855 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30288700 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30289425 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30289805 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study 30291058 — Surrogate Endpoint (SUR): Blood pressure
Study 30291112 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30291379 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study 30291379 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30291379 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 30291925 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 30292651 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 30292675 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study 30292675 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 30292675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 30292675 — Predictive Biomarker (PRD): ALOX15 mRNA
Genes: ALOX15; LOG15
Study 30293873 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 30295816 — Surrogate Endpoint (SUR): Serum testosterone
Study 30295822 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 30296840 — Surrogate Endpoint (SUR): Blood pressure
Study 30297124 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30297385 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 30298070 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30298444 — Surrogate Endpoint (SUR): Blood pressure
Study 30298568 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30299230 — Surrogate Endpoint (SUR): Blood pressure
Study 30302599 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 30302762 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30304652 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30305055 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30305055 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 30305055 — Predictive Biomarker (PRD): CLEC4D mRNA
Genes: CLEC4D; CLECSF8; MCL
Study 30305055 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 30305055 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 30305961 — Surrogate Endpoint (SUR): Blood pressure
Study 30306125 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 30306221 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 30306221 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30306221 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 30306221 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30307609 — Surrogate Endpoint (SUR): Blood pressure
Study 30309321 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30309342 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 30309342 — Surrogate Endpoint (SUR): Serum creatinine
Study 30309758 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 30310267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 30310267 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30312482 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30312541 — Predictive Biomarker (PRD): DLL1 mRNA
Genes: DLL1; UNQ146/PRO172
Study 30312541 — Predictive Biomarker (PRD): POSTN mRNA
Genes: POSTN; OSF2
Study 30315349 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 30315349 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 30315349 — Safety Biomarker (SAF): Reactive oxygen species
Study 30316935 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30317494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30318513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 30318646 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 30318722 — Predictive Biomarker (PRD): ZNF429 mRNA
Genes: ZNF429
Study 30318722 — Predictive Biomarker (PRD): ZNF493 mRNA
Genes: ZNF493
Study 30321257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1