TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10482997 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 10482997 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 10482997 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 2017535 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 28103948 — Surrogate Endpoint (SUR): Blood pressure
Study 18308157 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9526578 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 27398992 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3886209 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29499522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26971332 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28165634 — Predictive Biomarker (PRD): CACNA1G mRNA
Genes: CACNA1G; KIAA1123
Study 28165634 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CACNA1H mRNA
Genes: CACNA1H
Study 28165634 — Predictive Biomarker (PRD): CACNA1I mRNA
Genes: CACNA1I; KIAA1120
Study 28165634 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 21459891 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10733168 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 6713266 — Surrogate Endpoint (SUR): Blood pressure
Study 12415061 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7497558 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2023098 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2023098 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19640331 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17244765 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 21362327 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14693169 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 14693169 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 6425893 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 6425893 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29843492 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20826963 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16873779 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 10954063 — Predictive Biomarker (PRD): HBEGF mRNA
Genes: HBEGF; DTR; DTS; HEGFL
Study 8777332 — Predictive Biomarker (PRD): AKR1B1 mRNA
Genes: AKR1B1; ALDR1; ALR2
Study 30485224 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11052580 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6695835 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 20528232 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18662969 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31152533 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31152533 — Surrogate Endpoint (SUR): Blood pressure
Study 23879671 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 23879671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11704378 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11704378 — Safety Biomarker (SAF): Reactive oxygen species
Study 2564505 — Surrogate Endpoint (SUR): Blood pressure
Study 30716942 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28747487 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 21365345 — Predictive Biomarker (PRD): SFRP1 mRNA
Genes: SFRP1; FRP; FRP1; SARP2
Study 21365345 — Predictive Biomarker (PRD): LEF1 mRNA
Genes: LEF1
Study 21365345 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 7519694 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21347968 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8923359 — Surrogate Endpoint (SUR): Bone mineral density
Study 3535473 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27207552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7229121 — Surrogate Endpoint (SUR): Blood pressure
Study 31299352 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26378687 — Surrogate Endpoint (SUR): Blood pressure
Study 15001195 — Surrogate Endpoint (SUR): Blood pressure
Study 15001195 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2873440 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 31802559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29760009 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 6407047 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 6407047 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 31254340 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 31254340 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 31254340 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20590736 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16270633 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24766179 — Surrogate Endpoint (SUR): Blood pressure
Study 17261462 — Surrogate Endpoint (SUR): Blood pressure
Study 12593999 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 28942094 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 28942094 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 19524176 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 3132428 — Surrogate Endpoint (SUR): Blood pressure
Study 26475802 — Safety Biomarker (SAF): 51Cr-EDTA
Study 7804386 — Surrogate Endpoint (SUR): Blood pressure
Study 31799628 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 24047763 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16741261 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8404942 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3027601 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12842988 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study 12842988 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 12842988 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 12842988 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYH11 mRNA
Genes: MYH11; KIAA0866
Study 8741364 — Surrogate Endpoint (SUR): Bone mineral density
Study 8741364 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26297029 — Surrogate Endpoint (SUR): Blood pressure
Study 9891197 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2454355 — Surrogate Endpoint (SUR): Blood pressure
Study 27875516 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8334339 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30129815 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 24022919 — Surrogate Endpoint (SUR): Blood pressure
Study 17446206 — Surrogate Endpoint (SUR): Blood pressure
Study 28276001 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16525816 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 16525816 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16525816 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12740037 — Surrogate Endpoint (SUR): Blood pressure
Study 10740549 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1577399 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22314458 — Surrogate Endpoint (SUR): Serum creatinine
Study 17587394 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17587394 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7634283 — Surrogate Endpoint (SUR): Blood pressure
Study 2454357 — Surrogate Endpoint (SUR): Blood pressure
Study 25792708 — Predictive Biomarker (PRD): BET1 mRNA
Genes: BET1
Study 17379979 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8720348 — Surrogate Endpoint (SUR): Blood pressure
Study 2565841 — Surrogate Endpoint (SUR): Blood pressure
Study 3093 — Surrogate Endpoint (SUR): Blood pressure
Study 21663648 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16728452 — Surrogate Endpoint (SUR): Blood pressure
Study 17396618 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7725883 — Surrogate Endpoint (SUR): Blood pressure
Study 19409578 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 19409578 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 26912543 — Surrogate Endpoint (SUR): Total kidney volume
Study 20646510 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17959591 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17959591 — Surrogate Endpoint (SUR): Blood pressure
Study 14617323 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 14617323 — Surrogate Endpoint (SUR): Serum potassium
Study 23019944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19318455 — Surrogate Endpoint (SUR): Bone mineral density
Study 11599198 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31712617 — Predictive Biomarker (PRD): CA4 mRNA
Genes: CA4
Study 31712617 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 31712617 — Predictive Biomarker (PRD): CA2 mRNA
Genes: CA2
Study 22003869 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 8312032 — Surrogate Endpoint (SUR): Blood pressure
Study 18000162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18000162 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15882894 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8873580 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 8873580 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1526086 — Surrogate Endpoint (SUR): Blood pressure
Study 26924381 — Surrogate Endpoint (SUR): Blood pressure
Study 20536790 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 20536790 — Surrogate Endpoint (SUR): Blood pressure
Study 9426022 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2469711 — Monitoring Biomarker (MOI): HBV DNA
Study 26352813 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21836088 — Surrogate Endpoint (SUR): Blood pressure
Study 16758644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7587254 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31715161 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23124798 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 21044166 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17531578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17531578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17531578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15768732 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9740159 — Surrogate Endpoint (SUR): Blood pressure
Study 27939076 — Predictive Biomarker (PRD): LOXL2 mRNA
Genes: LOXL2
Study 25545744 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17580441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27695978 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27695978 — Surrogate Endpoint (SUR): Blood pressure
Study 29797695 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 29797695 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 29797695 — Predictive Biomarker (PRD): miR-135a
Study 16647506 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 2857087 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17512795 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 16138333 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16138333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7791814 — Surrogate Endpoint (SUR): Serum creatinine
Study 30531419 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 30531419 — Surrogate Endpoint (SUR): Blood pressure
Study 27004301 — Surrogate Endpoint (SUR): Blood pressure
Study 332100 — Surrogate Endpoint (SUR): Serum uric acid
Study 31281056 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28011155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28011155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28011155 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 9151915 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30346850 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31146493 — Predictive Biomarker (PRD): SDC1 mRNA
Genes: SDC1; SDC
Study 27356547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24785136 — Surrogate Endpoint (SUR): Blood pressure
Study 21288350 — Surrogate Endpoint (SUR): Blood pressure
Study 18849016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12423518 — Safety Biomarker (SAF): Protein AMBP
Genes: AMBP; HCP; ITIL
Study 12423518 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 30006305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23942869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17369807 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31590286 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 28697789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28697789 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28697789 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28697789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21989078 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 21989078 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 21989078 — Predictive Biomarker (PRD): SLC29A4 mRNA
Genes: SLC29A4; ENT4; PMAT; PSEC0113
Study 8727681 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 6119558 — Surrogate Endpoint (SUR): Blood pressure
Study 31806191 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 7937272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17465700 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 17465700 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16810279 — Surrogate Endpoint (SUR): Blood pressure
Study 9476862 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 9476862 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 27072880 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 19079943 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 19079943 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 15179192 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 26534930 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 8179048 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31932084 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31932084 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 27632197 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 16084803 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16084803 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12451009 — Surrogate Endpoint (SUR): Blood pressure
Study 8384659 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 30666367 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH
Study 19372524 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16761194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26860879 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 9485066 — Predictive Biomarker (PRD): ATXN1 mRNA
Genes: ATXN1; ATX1; SCA1
Study 28251152 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 27504739 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 27504739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24997826 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 24997826 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20863330 — Surrogate Endpoint (SUR): Bone mineral density
Study 7733026 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30878017 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 16983507 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 16276165 — Surrogate Endpoint (SUR): Serum creatinine
Study 30068285 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28064113 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 14671407 — Surrogate Endpoint (SUR): Blood pressure
Study 10193729 — Surrogate Endpoint (SUR): Serum triglycerides
Study 1975526 — Predictive Biomarker (PRD): HINT1 mRNA
Genes: HINT1; HINT; PKCI1; PRKCNH1
Study 31495497 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 20887370 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study 19371826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15155310 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11686425 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11686425 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11686425 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8290386 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 8290386 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8290386 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 2845769 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 21332970 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 16312168 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25043636 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24526136 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24526136 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20140250 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20140250 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 14721990 — Surrogate Endpoint (SUR): Blood pressure
Study 14721990 — Surrogate Endpoint (SUR): Serum creatinine
Study 10982756 — Surrogate Endpoint (SUR): Bone mineral density
Study 8736279 — Surrogate Endpoint (SUR): Blood pressure
Study 22917623 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21791470 — Predictive Biomarker (PRD): MAGEC1 mRNA
Genes: MAGEC1
Study 21791470 — Predictive Biomarker (PRD): MAGEB2 mRNA
Genes: MAGEB2
Study 21791470 — Predictive Biomarker (PRD): MAGEA6 mRNA
Genes: MAGEA6; MAGE6
Study 21791470 — Predictive Biomarker (PRD): NUF2 mRNA
Genes: NUF2; CDCA1; NUF2R
Study 21791470 — Predictive Biomarker (PRD): MAGEA9 mRNA
Genes: MAGEA9; MAGE9; MAGEA9A; MAGEA9B
Study 21791470 — Predictive Biomarker (PRD): CTAG2 mRNA
Genes: CTAG2; ESO2; LAGE1
Study 16846539 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12766755 — Surrogate Endpoint (SUR): Blood pressure
Study 31339403 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27544584 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24871666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22365947 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22365947 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12174378 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17519642 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 15471832 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 8094168 — Surrogate Endpoint (SUR): Blood pressure
Study 25605843 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25605843 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 25605843 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23263176 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16797388 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 16797388 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 6429229 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 10445600 — Surrogate Endpoint (SUR): Bone mineral density
Study 30579966 — Predictive Biomarker (PRD): NRM mRNA
Genes: NRM; NRM29; UNQ555/PRO1112
Study 30579966 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20435238 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18544168 — Surrogate Endpoint (SUR): Blood pressure
Study 14715345 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11689803 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 9297428 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 31942840 — Surrogate Endpoint (SUR): Serum creatinine