TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23433435 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18971537 — Surrogate Endpoint (SUR): Blood pressure
Study 10946911 — Predictive Biomarker (PRD): Hormone receptor
Study 28133908 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 28133908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28133908 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24312277 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12686329 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12686329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7573993 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28951368 — Predictive Biomarker (PRD): ILK mRNA
Genes: ILK; ILK1; ILK2
Study 19939650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19939650 — Surrogate Endpoint (SUR): Serum calcium
Study 19729323 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 19729323 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 9027670 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8312583 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 25005327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23252007 — Surrogate Endpoint (SUR): Serum creatinine
Study 12817109 — Surrogate Endpoint (SUR): Blood pressure
Study 21799772 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19489942 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19489942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23828329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23828329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23828329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11349008 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 9462194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9462194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23890405 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 2037387 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28489464 — Surrogate Endpoint (SUR): Blood pressure
Study 22013957 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20215461 — Surrogate Endpoint (SUR): Blood pressure
Study 12430779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12430779 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8814371 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 1330574 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29903826 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 26999985 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 20932069 — Surrogate Endpoint (SUR): Bone mineral density
Study 8398496 — Surrogate Endpoint (SUR): Blood pressure
Study 29847509 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 29847509 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 29847509 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 29847509 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 29847509 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 29847509 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 29847509 — Predictive Biomarker (PRD): HTR2B mRNA
Genes: HTR2B
Study 29847509 — Predictive Biomarker (PRD): HTR2C mRNA
Genes: HTR2C; HTR1C
Study 27418968 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 27418968 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24079062 — Surrogate Endpoint (SUR): Blood pressure
Study 16126801 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9367476 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1315121 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28980293 — Surrogate Endpoint (SUR): Blood pressure
Study 27632909 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27632909 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20533217 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20533217 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16414385 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8379600 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24895799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22935955 — Surrogate Endpoint (SUR): Blood pressure
Study 18664026 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 6356899 — Surrogate Endpoint (SUR): Blood pressure
Study 28361739 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 26518479 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 7713201 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3372274 — Surrogate Endpoint (SUR): Blood pressure
Study 15339999 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11228382 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1092210 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28463756 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28463756 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28463756 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 26109992 — Surrogate Endpoint (SUR): Blood pressure
Study 26109992 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26109992 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9252712 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8325946 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27085126 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27085126 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 27085126 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 24839206 — Safety Biomarker (SAF): Interleukin 1
Study 18359186 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12084809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28559399 — Surrogate Endpoint (SUR): Blood pressure
Study 25222091 — Surrogate Endpoint (SUR): Blood pressure
Study 19543909 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19543909 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24252311 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 17643277 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15863650 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 15863650 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9535147 — Surrogate Endpoint (SUR): Blood pressure
Study 7702050 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2719498 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2719498 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18717761 — Predictive Biomarker (PRD): AEN mRNA
Genes: AEN; ISG20L1; SBBI58
Study 16210020 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 7854531 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 23529173 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21817186 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9777834 — Surrogate Endpoint (SUR): Serum creatinine
Study 27590372 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 20646533 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 20646533 — Surrogate Endpoint (SUR): Bone mineral density
Study 16350715 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 10594411 — Surrogate Endpoint (SUR): Blood pressure
Study 31182139 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 31182139 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23551127 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11158406 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11158406 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7519005 — Surrogate Endpoint (SUR): Blood pressure
Study 25707380 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 18635724 — Surrogate Endpoint (SUR): Blood pressure
Study 17065274 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10752747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10752747 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29354928 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29354928 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29354928 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 20625263 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9643277 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24290290 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27879654 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 27879654 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 10215657 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 22453774 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15801015 — Surrogate Endpoint (SUR): Bone mineral density
Study 29378708 — Surrogate Endpoint (SUR): Serum creatinine
Study 27310327 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 27310327 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 21715138 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21715138 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18495607 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15677599 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 11240980 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 1361746 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28475670 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23396736 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 23396736 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 15754082 — Surrogate Endpoint (SUR): Bone mineral density
Study 22151932 — Predictive Biomarker (PRD): SMG1 mRNA
Genes: SMG1; ATX; KIAA0421; LIP
Study 16720126 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28407271 — Monitoring Biomarker (MOI): HBV DNA
Study 15320990 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3878905 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 3878905 — Surrogate Endpoint (SUR): Serum creatinine
Study 3878905 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 12069111 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 15794869 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 12872394 — Safety Biomarker (SAF): IL16
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 10697624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 971343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28533305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28533305 — Surrogate Endpoint (SUR): Blood pressure
Study 28533305 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28533305 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16365070 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 16365070 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 10827226 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 10827226 — Surrogate Endpoint (SUR): Serum sodium
Study 1608903 — Surrogate Endpoint (SUR): Blood pressure
Study 3885701 — Surrogate Endpoint (SUR): Blood pressure
Study 3885701 — Surrogate Endpoint (SUR): Serum potassium
Study 3885701 — Surrogate Endpoint (SUR): Serum uric acid
Study 26568577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24798768 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 8523872 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28176175 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 28176175 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28176175 — Predictive Biomarker (PRD): Hormone receptor
Study 7946939 — Surrogate Endpoint (SUR): Blood pressure
Study 1454657 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22958175 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 22958175 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 15295694 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9831304 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 9831304 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 19709691 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12072586 — Surrogate Endpoint (SUR): Blood pressure
Study 7985892 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2154407 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2154407 — Surrogate Endpoint (SUR): Blood pressure
Study 28062085 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 24216113 — Surrogate Endpoint (SUR): Blood pressure
Study 19133058 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28716656 — Surrogate Endpoint (SUR): Blood pressure
Study 26063503 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 26063503 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 23151750 — Surrogate Endpoint (SUR): Serum potassium
Study 23151750 — Surrogate Endpoint (SUR): Blood pressure
Study 15360994 — Surrogate Endpoint (SUR): Blood pressure
Study 8376688 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20363993 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19005437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31288740 — Surrogate Endpoint (SUR): Blood pressure
Study 28077858 — Surrogate Endpoint (SUR): Blood pressure
Study 19405039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3513684 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30939096 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30422235 — Surrogate Endpoint (SUR): Blood pressure
Study 30422235 — Surrogate Endpoint (SUR): Total kidney volume
Study 26987626 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 26987626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31122894 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26218727 — Safety Biomarker (SAF): Hyaluronic acid
Study 23967286 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21844821 — Surrogate Endpoint (SUR): Blood pressure
Study 19625744 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11167431 — Surrogate Endpoint (SUR): Blood pressure
Study 11229246 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23944632 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 20679528 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 20679528 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 8958019 — Surrogate Endpoint (SUR): Bone mineral density
Study 1547962 — Safety Biomarker (SAF): Hyaluronic acid
Study 3873582 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21490523 — Surrogate Endpoint (SUR): Blood pressure
Study 15010071 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15010071 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15010071 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3068191 — Surrogate Endpoint (SUR): Blood pressure
Study 21632815 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 18823693 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11079651 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 15638820 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15638820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7727181 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7727181 — Surrogate Endpoint (SUR): Blood pressure
Study 15554350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15554350 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15554350 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24858657 — Surrogate Endpoint (SUR): Blood pressure
Study 22344613 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 21403038 — Surrogate Endpoint (SUR): Blood pressure
Study 21403038 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19135567 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19135567 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14734128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14734128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14734128 — Safety Biomarker (SAF): IL-6 and IL-10
Study 11726454 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11726454 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 11726454 — Surrogate Endpoint (SUR): Blood pressure
Study 7873465 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16526560 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 10644869 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8795443 — Surrogate Endpoint (SUR): Blood pressure
Study 30359862 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24360978 — Surrogate Endpoint (SUR): Blood pressure
Study 24360978 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24360978 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24360978 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23786894 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21794791 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 19366845 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18515308 — Surrogate Endpoint (SUR): Serum calcium
Study 18515308 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 15871845 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22926446 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 20435656 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20435656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20435656 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10898322 — Monitoring Biomarker (MOI): HBV DNA
Study 2115613 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31060615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14614004 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10721197 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19180837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1974513 — Surrogate Endpoint (SUR): Blood pressure
Study 30478094 — Surrogate Endpoint (SUR): Complete renal response
Study 28759403 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23771713 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 28319494 — Predictive Biomarker (PRD): SLBP mRNA
Genes: SLBP; HBP
Study 15364775 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18442638 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15890685 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 15890685 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8075028 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 8075028 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 2609991 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2609991 — Surrogate Endpoint (SUR): Blood pressure
Study 29524398 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 27625301 — Surrogate Endpoint (SUR): Bone mineral density
Study 17823597 — Surrogate Endpoint (SUR): Blood pressure
Study 15751670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2