TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21860339 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19387646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9645802 — Surrogate Endpoint (SUR): Blood pressure
Study 9645802 — Surrogate Endpoint (SUR): Serum creatinine
Study 23488545 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19619700 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11128341 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11128341 — Surrogate Endpoint (SUR): Blood pressure
Study 30345611 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25157013 — Surrogate Endpoint (SUR): Blood pressure
Study 21971356 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17977528 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 31588557 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31588557 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21631509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18832879 — Surrogate Endpoint (SUR): Serum creatinine
Study 24401359 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 1873003 — Surrogate Endpoint (SUR): Blood pressure
Study 29908708 — Surrogate Endpoint (SUR): Blood pressure
Study 25247335 — Predictive Biomarker (PRD): IGF2BP2 mRNA
Genes: IGF2BP2; IMP2; VICKZ2
Study 25247335 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25247335 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25247335 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17968997 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 17968997 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 3534848 — Surrogate Endpoint (SUR): Blood pressure
Study 3534848 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23786793 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25226004 — Safety Biomarker (SAF): Hyaluronic acid
Study 25226004 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 22776534 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 11850979 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7949544 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2884410 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 27026570 — Surrogate Endpoint (SUR): Blood pressure
Study 22633317 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12067837 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6306038 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27930497 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 26869049 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 26869049 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26869049 — Surrogate Endpoint (SUR): Pathological complete response
Study 16079640 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16079640 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18808333 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21264830 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 21264830 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 21264830 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 14583341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14583341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14583341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25572450 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 25572450 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 25572450 — Predictive Biomarker (PRD): CHRNB4 mRNA
Genes: CHRNB4
Study 1839644 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 30189282 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 30189282 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28138958 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 22611676 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27736113 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 22170479 — Safety Biomarker (SAF): Interleukin 12
Study 9224205 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20608354 — Surrogate Endpoint (SUR): Blood pressure
Study 11788637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11788637 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11788637 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9872813 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24569485 — Surrogate Endpoint (SUR): Blood pressure
Study 7652119 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 2499481 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 26092816 — Predictive Biomarker (PRD): Hormone receptor
Study 27146169 — Surrogate Endpoint (SUR): Bone mineral density
Study 12623838 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12623838 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24898221 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24898221 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19825059 — Surrogate Endpoint (SUR): Blood pressure
Study 9407458 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9407458 — Surrogate Endpoint (SUR): Blood pressure
Study 29141041 — Surrogate Endpoint (SUR): Blood pressure
Study 21975318 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 18471455 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15909609 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 25220909 — Predictive Biomarker (PRD): POSTN mRNA
Genes: POSTN; OSF2
Study 25220909 — Predictive Biomarker (PRD): RUNX2 mRNA
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 25220909 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22898035 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 11527645 — Surrogate Endpoint (SUR): Blood pressure
Study 23852652 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23852652 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23852652 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23852652 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 18501650 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1321490 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21760585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18057337 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15642859 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 26707054 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 23972415 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 16616656 — Surrogate Endpoint (SUR): Serum creatinine
Study 11004352 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30515970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21244523 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 3858894 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 21051458 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19337241 — Surrogate Endpoint (SUR): Blood pressure
Study 15190528 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 28506917 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 28506917 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 19221299 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15341255 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9149164 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29871197 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24317176 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16238116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 31599476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27836862 — Predictive Biomarker (PRD): TWSG1 mRNA
Genes: TWSG1; TSG; PSEC0250
Study 25801556 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 17346444 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 9102589 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 1654739 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1654739 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1654739 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16510768 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 15585154 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8498495 — Surrogate Endpoint (SUR): Blood pressure
Study 8498495 — Surrogate Endpoint (SUR): Serum potassium
Study 8498495 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29391265 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29391265 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18166090 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12628113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28259141 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28259141 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17049679 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28318450 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28318450 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28318450 — Safety Biomarker (SAF): BDNF
Study 28318450 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25741644 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 19010165 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 19010165 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23886205 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21844075 — Surrogate Endpoint (SUR): Serum creatinine
Study 21844075 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23732552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23732552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19894376 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 19894376 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17040925 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16446080 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16446080 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 3703632 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26208959 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 16616235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16616235 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31429514 — Surrogate Endpoint (SUR): Blood pressure
Study 26919833 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 24652518 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24652518 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 24652518 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18008230 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7738626 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7738626 — Surrogate Endpoint (SUR): Serum creatinine
Study 25307158 — Surrogate Endpoint (SUR): Blood pressure
Study 22481014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22481014 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16981901 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28148492 — Predictive Biomarker (PRD): SLC9A1 mRNA
Genes: SLC9A1; APNH1; NHE1
Study 28148492 — Predictive Biomarker (PRD): MCTS1 mRNA
Genes: MCTS1; MCT1
Study 28148492 — Predictive Biomarker (PRD): SLC16A4 mRNA
Genes: SLC16A4; MCT4; MCT5
Study 22151785 — Surrogate Endpoint (SUR): Blood pressure
Study 8115670 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 23431246 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 6614662 — Surrogate Endpoint (SUR): Serum potassium
Study 20634797 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2529028 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 11181464 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2916912 — Surrogate Endpoint (SUR): Bone mineral density
Study 31953696 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31953696 — Surrogate Endpoint (SUR): Pathological complete response
Study 31953696 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22032731 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 22032731 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 16633143 — Predictive Biomarker (PRD): NE
Study 27566331 — Surrogate Endpoint (SUR): Blood pressure
Study 24198051 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24198051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15205717 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 11723148 — Surrogate Endpoint (SUR): Blood pressure
Study 25443802 — Surrogate Endpoint (SUR): Blood pressure
Study 25443802 — Surrogate Endpoint (SUR): Serum creatinine
Study 21126970 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21126970 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21126970 — Surrogate Endpoint (SUR): Blood pressure
Study 17661330 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 8390009 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 28198712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28198712 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28198712 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28198712 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 28198712 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10846910 — Surrogate Endpoint (SUR): Blood pressure
Study 22153890 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22153890 — Predictive Biomarker (PRD): Hormone receptor
Study 20682679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17878180 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15753235 — Surrogate Endpoint (SUR): Blood pressure
Study 23388346 — Surrogate Endpoint (SUR): Bone mineral density
Study 11552869 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8677191 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8677191 — Surrogate Endpoint (SUR): Blood pressure
Study 24855368 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24855368 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18831744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12944570 — Surrogate Endpoint (SUR): Serum creatinine
Study 30346511 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23714670 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20637390 — Surrogate Endpoint (SUR): Blood pressure
Study 1477017 — Surrogate Endpoint (SUR): Blood pressure
Study 31324181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17823084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3073869 — Monitoring Biomarker (MOI): HBV DNA
Study 29026111 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 17476291 — Surrogate Endpoint (SUR): Blood pressure
Study 17476291 — Surrogate Endpoint (SUR): Serum creatinine
Study 7876651 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 7512583 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19213790 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 8062354 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 31561322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12602538 — Predictive Biomarker (PRD): VCAM1 mRNA
Genes: VCAM1
Study 8813038 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16410483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16410483 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31887617 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 29178917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16796137 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9220221 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8421977 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8421977 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11398073 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 29615792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29615792 — Surrogate Endpoint (SUR): Blood pressure
Study 16209961 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 10522954 — Surrogate Endpoint (SUR): Bone mineral density
Study 1362189 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22075273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22075273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15197669 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9717036 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 28490394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23775967 — Monitoring Biomarker (MOI): HBV DNA
Study 12565981 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 11004045 — Surrogate Endpoint (SUR): Blood pressure
Study 22701339 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22701339 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 24991946 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23615154 — Surrogate Endpoint (SUR): Blood pressure
Study 19075278 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 9024172 — Surrogate Endpoint (SUR): Blood pressure
Study 26656783 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17702725 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 11413660 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7995270 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22282300 — Surrogate Endpoint (SUR): Bone mineral density
Study 31082916 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30027600 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29231360 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 29231360 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9585285 — Surrogate Endpoint (SUR): Blood pressure
Study 31390330 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19196886 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19196886 — Surrogate Endpoint (SUR): Blood pressure
Study 16234834 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 9321530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3081918 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 31432705 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 25023807 — Safety Biomarker (SAF): Cytochrome c