TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04595136 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00156520 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT01429311 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00722397 — Predictive Biomarker (PRD): TRIM27 mRNA
Genes: TRIM27; RFP; RNF76
Study NCT02151695 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02151695 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00439023 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03624231 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02590692 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT01566305 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT02111226 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01074372 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00606255 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01393080 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01393080 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03815474 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT03815474 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03815474 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT03122730 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02127710 — Predictive Biomarker (PRD): PRCC mRNA
Genes: PRCC; TPRC
Study NCT02127710 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00688090 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study NCT02979197 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01254071 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03270176 — Predictive Biomarker (PRD): DIABLO mRNA
Genes: DIABLO; SMAC
Study NCT01373996 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00089843 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04176159 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT03604757 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01503840 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00033774 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04371978 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03839498 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04893746 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05166993 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03052608 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03108066 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT04757285 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT04776460 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02215096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02215096 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT04080960 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03078400 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT00390455 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00390455 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00390455 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00668499 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02524405 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02524405 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT03838146 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00834678 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02876094 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT03237078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01876186 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02652832 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02652832 — Safety Biomarker (SAF): BDNF
Study NCT04295785 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study NCT04127942 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00447005 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT02772887 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02095197 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study NCT03327285 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00293852 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00849082 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04410471 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00257738 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01033630 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00053573 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT01282658 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01373489 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00589888 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00589888 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05474235 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT04099407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04099407 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT02103231 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01820871 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04111809 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study NCT01057095 — Predictive Biomarker (PRD): PLAGL2 mRNA
Genes: PLAGL2; KIAA0198
Study NCT00089414 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03126136 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01484041 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01482156 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02991144 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT02970916 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03534986 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00994929 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00994929 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study NCT04123275 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT02020135 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02579096 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT04568421 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01963507 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01963507 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02187003 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03270644 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02179515 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT02179515 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT03028103 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03160482 — Predictive Biomarker (PRD): PCSK6 mRNA
Genes: PCSK6; PACE4
Study NCT00366301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00446862 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01601132 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT04091737 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00343577 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00343577 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05562687 — Predictive Biomarker (PRD): APLNR mRNA
Genes: APLNR; AGTRL1; APJ
Study NCT01851070 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02848703 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT01364077 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00796510 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT02288767 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00804622 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05285787 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT05300334 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT04425681 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04425681 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04425681 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04425681 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03511664 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02096237 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT01771042 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00579098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04121455 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03559387 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT03841448 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02135770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03088371 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00287365 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study NCT01076920 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01479023 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT01346579 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT00926744 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01662466 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00397215 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00003961 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02949531 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03176446 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01777958 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03412526 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03715101 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01167842 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01167842 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT01167842 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study NCT02829333 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01874106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01874106 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00002449 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00002449 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01291680 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04275934 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02827227 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT02827227 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02235805 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01354587 — Predictive Biomarker (PRD): PIDD1 mRNA
Genes: PIDD1; LRDD; PIDD
Study NCT04300179 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT00433953 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study NCT00347360 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03745807 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT01047670 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02025114 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03801304 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03801304 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03801304 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03801304 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03801304 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04060225 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03961880 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03961880 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01155037 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01086566 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02842359 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02842359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02225977 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study NCT02225977 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study NCT04034459 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01988896 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02093416 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT00747123 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04952285 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00239109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03531931 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03531931 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00289016 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00994773 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00477477 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04177264 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01613534 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT00431288 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01790932 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01790932 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01790932 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01340729 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study NCT03110094 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04472533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04472533 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT04472533 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01617681 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02650427 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT02137083 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02137083 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06651437 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03764215 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03764215 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT03764215 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study NCT00432419 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02622620 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT01570556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00683085 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00683085 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04716088 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01960465 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01937754 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04349254 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04260711 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT02959918 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03557138 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04352777 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04352777 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT01785420 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01785420 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02324998 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT04429048 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study NCT00868478 — Predictive Biomarker (PRD): CD74 mRNA
Genes: CD74; DHLAG
Study NCT03213392 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03189485 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00529984 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01978418 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study NCT00593918 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT02587949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02587949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03731845 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01150903 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT04263298 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04263298 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03158389 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT01160211 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01160211 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00676338 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01699490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03076619 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03076619 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00000471 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00987545 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT01741090 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02641457 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03104608 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00507221 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01233609 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00875979 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01068834 — Predictive Biomarker (PRD): KIF6 mRNA
Genes: KIF6; C6orf102
Study NCT00705926 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00001688 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02873390 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02873390 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01115543 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT02812953 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study NCT02812953 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT01342276 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01118871 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01827722 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01827722 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05836181 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02371759 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03495037 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01210222 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003