TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20972285 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12741449 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 10574587 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10574587 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10574587 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30391914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25782451 — Predictive Biomarker (PRD): miR-409-3p
Genes: MIR409
Study 25156622 — Surrogate Endpoint (SUR): Serum creatinine
Study 9858319 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29019297 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 22503722 — Surrogate Endpoint (SUR): Bone mineral density
Study 20435196 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6289856 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26879200 — Surrogate Endpoint (SUR): Bone mineral density
Study 15902741 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 15902741 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 15902741 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 15902741 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6401426 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30716509 — Surrogate Endpoint (SUR): Blood pressure
Study 26712474 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25161182 — Surrogate Endpoint (SUR): Blood pressure
Study 17950801 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12089124 — Surrogate Endpoint (SUR): Blood pressure
Study 10480520 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24956454 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 17305652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17305652 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 25448491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23883653 — Surrogate Endpoint (SUR): Blood pressure
Study 19032600 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 31362999 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21565490 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 21565490 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 8257447 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8257447 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 8257447 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23020133 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 23020133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20124218 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12828169 — Surrogate Endpoint (SUR): Blood pressure
Study 1639047 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31766627 — Surrogate Endpoint (SUR): Blood pressure
Study 22569241 — Safety Biomarker (SAF): Reactive oxygen species
Study 17493526 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 17493526 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 17493526 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 17493526 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17493526 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 17493526 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 17493526 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 15716708 — Surrogate Endpoint (SUR): Blood pressure
Study 7493424 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 30915963 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 21223512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21223512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21223512 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 21223512 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21223512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26269397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25261913 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 12460326 — Surrogate Endpoint (SUR): Blood pressure
Study 7014814 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 22490579 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 22490579 — Safety Biomarker (SAF): Cytochrome c
Study 22490579 — Safety Biomarker (SAF): Reactive oxygen species
Study 14583186 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 10553829 — Surrogate Endpoint (SUR): Blood pressure
Study 28207527 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26180243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23979955 — Surrogate Endpoint (SUR): Bone mineral density
Study 2985351 — Surrogate Endpoint (SUR): Blood pressure
Study 26051802 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31679359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31679359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31679359 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31679359 — Surrogate Endpoint (SUR): Blood pressure
Study 31679359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31679359 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31679359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27913695 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 26291797 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 17577032 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 29144812 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 24571582 — Surrogate Endpoint (SUR): Serum testosterone
Study 19462276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21121874 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 24622804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18812608 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23270535 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23270535 — Surrogate Endpoint (SUR): Blood pressure
Study 10512899 — Surrogate Endpoint (SUR): Blood pressure
Study 10595045 — Surrogate Endpoint (SUR): Blood pressure
Study 9973031 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28404531 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28404531 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25742716 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 19798097 — Surrogate Endpoint (SUR): Blood pressure
Study 16487912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16487912 — Safety Biomarker (SAF): Reactive oxygen species
Study 16487912 — Safety Biomarker (SAF): Interleukin 1
Study 10836728 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10836728 — Surrogate Endpoint (SUR): Blood pressure
Study 30201408 — Predictive Biomarker (PRD): LPAR1 mRNA
Genes: LPAR1; EDG2; LPA1
Study 19713965 — Surrogate Endpoint (SUR): Blood pressure
Study 16449345 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15033935 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8025745 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8025745 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25044795 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 25044795 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 25044795 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 25044795 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 25044795 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 25044795 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 25044795 — Predictive Biomarker (PRD): PPIA mRNA
Genes: PPIA; CYPA
Study 25044795 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 25044795 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 25044795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25044795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22840549 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 20377532 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 8215790 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3525237 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10579145 — Surrogate Endpoint (SUR): Serum calcium
Study 30412235 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 25157767 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 25157767 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19240178 — Predictive Biomarker (PRD): ABCC4 mRNA
Genes: ABCC4; MOATB; MRP4
Study 19240178 — Predictive Biomarker (PRD): ABCC5 mRNA
Genes: ABCC5; MRP5
Study 19240178 — Predictive Biomarker (PRD): ATP-binding cassette sub-family C member 11
Genes: ABCC11; MRP8
Study 28742529 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28742529 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28742529 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8957211 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 8957211 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8957211 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8957211 — Monitoring Biomarker (MOI): Complement C4
Study 3505731 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 29055531 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 24685020 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24685020 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12559939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6667814 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22340561 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11821455 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 7484753 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22825550 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16702892 — Surrogate Endpoint (SUR): Blood pressure
Study 28303751 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28303751 — Surrogate Endpoint (SUR): Blood pressure
Study 11345746 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22200806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15233676 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8363066 — Surrogate Endpoint (SUR): Blood pressure
Study 30361335 — Surrogate Endpoint (SUR): Blood pressure
Study 30690785 — Surrogate Endpoint (SUR): Bone mineral density
Study 30690785 — Surrogate Endpoint (SUR): Serum calcium
Study 30690785 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29474361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29474361 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20142594 — Predictive Biomarker (PRD): Microsatellite instability
Study 17377957 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17377957 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 17377957 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 12005116 — Surrogate Endpoint (SUR): Blood pressure
Study 7822659 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29070849 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 23574571 — Safety Biomarker (SAF): Hyaluronic acid
Study 31481105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31481105 — Surrogate Endpoint (SUR): Blood pressure
Study 25384624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15305945 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9386112 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7910053 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3064642 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24793567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24793567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24793567 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 24793567 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24173178 — Safety Biomarker (SAF): Hyaluronic acid
Study 17046545 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 17046545 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26549496 — Safety Biomarker (SAF): Interleukin 1
Study 27424688 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 24729492 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24729492 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20430115 — Surrogate Endpoint (SUR): Blood pressure
Study 12438948 — Surrogate Endpoint (SUR): Serum creatinine
Study 19966583 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 798282 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23399428 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18059502 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 6360571 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 25079861 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11967501 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 11967501 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 9847262 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7715343 — Monitoring Biomarker (MOI): HBV DNA
Study 17253995 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28012663 — Surrogate Endpoint (SUR): Urine free cortisol
Study 22080020 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 6179101 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15735805 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 2050832 — Surrogate Endpoint (SUR): Serum potassium
Study 2050832 — Surrogate Endpoint (SUR): Serum calcium
Study 6846677 — Surrogate Endpoint (SUR): Blood pressure
Study 29482433 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 8618603 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6705284 — Surrogate Endpoint (SUR): Blood pressure
Study 30016948 — Predictive Biomarker (PRD): GARS1 mRNA
Genes: GARS1; GARS
Study 24528690 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24528690 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24528690 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24528690 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24528690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10207545 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27181755 — Surrogate Endpoint (SUR): Serum creatinine
Study 22246660 — Surrogate Endpoint (SUR): Blood pressure
Study 1781820 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 1781820 — Surrogate Endpoint (SUR): Skeletal muscle dystrophin
Study 19329177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9048273 — Surrogate Endpoint (SUR): Blood pressure
Study 8151104 — Surrogate Endpoint (SUR): Plasma ammonia
Study 24556040 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23174050 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 23174050 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 8494129 — Surrogate Endpoint (SUR): Blood pressure
Study 26643687 — Surrogate Endpoint (SUR): Blood pressure
Study 16122472 — Surrogate Endpoint (SUR): Blood pressure
Study 25626413 — Surrogate Endpoint (SUR): Bone mineral density
Study 25626413 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21403011 — Surrogate Endpoint (SUR): Blood pressure
Study 8751806 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 28733270 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11734652 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30785868 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31880749 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28304227 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28304227 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 28304227 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28304227 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25442108 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25442108 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24787489 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 22928973 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15545060 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15545060 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9850017 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 9850017 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14566831 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10874273 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1452964 — Surrogate Endpoint (SUR): Blood pressure
Study 6531653 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26591358 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 26591358 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 26591358 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20118171 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 10566728 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6409958 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 26876351 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26876351 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19758763 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 14504028 — Surrogate Endpoint (SUR): Blood pressure
Study 11836043 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11836043 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31804186 — Surrogate Endpoint (SUR): Blood pressure
Study 12177729 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 8535321 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 21394642 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19714604 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 16298691 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9784084 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2021794 — Surrogate Endpoint (SUR): Bone mineral density
Study 2541975 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28113032 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28113032 — Predictive Biomarker (PRD): Hormone receptor