TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22486205 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22486205 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21635753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10702769 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 10702769 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 10702769 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10702769 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10702769 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10702769 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20963310 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19076083 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14572753 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 15312156 — Surrogate Endpoint (SUR): Blood pressure
Study 9023301 — Surrogate Endpoint (SUR): Blood pressure
Study 25270958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8704697 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8704697 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 1513973 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30791889 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 29246729 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29246729 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29246729 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 29246729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29246729 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22915298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18048435 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16037127 — Surrogate Endpoint (SUR): Blood pressure
Study 10573494 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30350405 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9327818 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17909084 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17909084 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17909084 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12760989 — Surrogate Endpoint (SUR): Blood pressure
Study 10847536 — Surrogate Endpoint (SUR): Probing pocket depth
Study 9181278 — Surrogate Endpoint (SUR): Blood pressure
Study 9181278 — Surrogate Endpoint (SUR): Serum creatinine
Study 21051087 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 16641430 — Monitoring Biomarker (MOI): HBV DNA
Study 10370615 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1667754 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28257146 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 9530481 — Surrogate Endpoint (SUR): Blood pressure
Study 452871 — Surrogate Endpoint (SUR): Blood pressure
Study 19411061 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19411061 — Surrogate Endpoint (SUR): Blood pressure
Study 29600837 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28619659 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23909039 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 7667826 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7667826 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25645909 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19262495 — Surrogate Endpoint (SUR): Blood pressure
Study 3621870 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3621870 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 3621870 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 29063598 — Surrogate Endpoint (SUR): Blood pressure
Study 28825973 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18202320 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 18202320 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18202320 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18202320 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18202320 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12857503 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 12857503 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15627725 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 31154289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15510039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31964674 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30501611 — Surrogate Endpoint (SUR): Blood pressure
Study 27581475 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27581475 — Surrogate Endpoint (SUR): Serum potassium
Study 20522354 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20522354 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 14617595 — Surrogate Endpoint (SUR): Blood pressure
Study 10719942 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3987180 — Surrogate Endpoint (SUR): Blood pressure
Study 20121745 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 17868655 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 12732885 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 29105841 — Surrogate Endpoint (SUR): Bone mineral density
Study 20370970 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 17395868 — Surrogate Endpoint (SUR): Bone mineral density
Study 14961215 — Surrogate Endpoint (SUR): Bone mineral density
Study 15795700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 10703873 — Surrogate Endpoint (SUR): Blood pressure
Study 24790069 — Surrogate Endpoint (SUR): Blood pressure
Study 24790069 — Surrogate Endpoint (SUR): Serum uric acid
Study 20703230 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20703230 — Surrogate Endpoint (SUR): Blood pressure
Study 17434727 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 2550644 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2550644 — Surrogate Endpoint (SUR): Blood pressure
Study 29185253 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17047022 — Surrogate Endpoint (SUR): Bone mineral density
Study 8746073 — Surrogate Endpoint (SUR): Bone mineral density
Study 19620514 — Surrogate Endpoint (SUR): Blood pressure
Study 15501783 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 15501783 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11675958 — Surrogate Endpoint (SUR): Blood pressure
Study 27820670 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 3548485 — Surrogate Endpoint (SUR): Blood pressure
Study 22732747 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 9873844 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17275695 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 7512124 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20196974 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 20196974 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20196974 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 8171738 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3534842 — Surrogate Endpoint (SUR): Blood pressure
Study 3534842 — Surrogate Endpoint (SUR): Serum potassium
Study 28099502 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11751698 — Surrogate Endpoint (SUR): Blood pressure
Study 24814202 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22349668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26423195 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23593139 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 21768545 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21768545 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21768545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11718031 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 167673 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30104102 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 23222963 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 23222963 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20961828 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20961828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12428180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10509549 — Surrogate Endpoint (SUR): Blood pressure
Study 28176336 — Surrogate Endpoint (SUR): Serum creatinine
Study 31559633 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 26449197 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22648840 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11099326 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11099326 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11099326 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25954758 — Predictive Biomarker (PRD): SHB mRNA
Genes: SHB
Study 21307169 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9520161 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2895483 — Safety Biomarker (SAF): DRD2
Study 29131129 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29131129 — Surrogate Endpoint (SUR): Blood pressure
Study 27036379 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 25539805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21092191 — Surrogate Endpoint (SUR): Blood pressure
Study 18707799 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 31139877 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28121185 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19075192 — Surrogate Endpoint (SUR): Bone mineral density
Study 19075192 — Surrogate Endpoint (SUR): Serum calcium
Study 7766795 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 2495220 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 337144 — Surrogate Endpoint (SUR): Blood pressure
Study 19802534 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 22699036 — Surrogate Endpoint (SUR): Blood pressure
Study 12235557 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 12235557 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 22978595 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20003205 — Safety Biomarker (SAF): Hyaluronic acid
Study 12875478 — Surrogate Endpoint (SUR): Blood pressure
Study 6342133 — Surrogate Endpoint (SUR): Blood pressure
Study 19558344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19558344 — Surrogate Endpoint (SUR): Serum creatinine
Study 12084664 — Surrogate Endpoint (SUR): Blood pressure
Study 9708611 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30290685 — Surrogate Endpoint (SUR): Bone mineral density
Study 22776106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20553388 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9041914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9041914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29426008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29426008 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29426008 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22408263 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 22408263 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 22408263 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 21430407 — Surrogate Endpoint (SUR): Bone mineral density
Study 3010693 — Surrogate Endpoint (SUR): Serum potassium
Study 27620393 — Surrogate Endpoint (SUR): Blood pressure
Study 30943337 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 30943337 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16876132 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8932993 — Surrogate Endpoint (SUR): Blood pressure
Study 22686204 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 15691267 — Surrogate Endpoint (SUR): Serum creatinine
Study 10480522 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26040181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7738212 — Surrogate Endpoint (SUR): Blood pressure
Study 1828417 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23996473 — Surrogate Endpoint (SUR): Bone mineral density
Study 22024822 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 12006122 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 12006122 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10071274 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 10071274 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27432441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6708603 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6708603 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6708603 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22421908 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22421908 — Surrogate Endpoint (SUR): Blood pressure
Study 30188494 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 22162541 — Surrogate Endpoint (SUR): Blood pressure
Study 27010143 — Monitoring Biomarker (MOI): HBV DNA
Study 20023215 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8092112 — Surrogate Endpoint (SUR): Serum creatinine
Study 17217744 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 17217744 — Surrogate Endpoint (SUR): Blood pressure
Study 10629434 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 10629434 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 7956716 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19259967 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 19259967 — Surrogate Endpoint (SUR): Serum testosterone
Study 15265253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15265253 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15265253 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11386930 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 28283937 — Surrogate Endpoint (SUR): Serum calcium
Study 26374766 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 23968656 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9772137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7598068 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21723766 — Surrogate Endpoint (SUR): Bone mineral density
Study 19689979 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 15181049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15181049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15181049 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15181049 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10785452 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 27546744 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1971592 — Surrogate Endpoint (SUR): Blood pressure
Study 27653153 — Surrogate Endpoint (SUR): Blood pressure
Study 17907113 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17907113 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17907113 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9530343 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 26328624 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26328624 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26328624 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26328624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8874076 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30962264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30962264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30962264 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22499291 — Surrogate Endpoint (SUR): Blood pressure
Study 20364590 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19091199 — Surrogate Endpoint (SUR): Blood pressure
Study 19091199 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29990228 — Surrogate Endpoint (SUR): Blood pressure
Study 23979914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6827423 — Surrogate Endpoint (SUR): Blood pressure
Study 24566440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24566440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24566440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24566440 — Safety Biomarker (SAF): Interleukin 1
Study 24566440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7638815 — Surrogate Endpoint (SUR): Blood pressure
Study 328335 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26610558 — Surrogate Endpoint (SUR): Blood pressure
Study 21940220 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 19673326 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19673326 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2030804 — Surrogate Endpoint (SUR): Blood pressure
Study 28119114 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23155025 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23155025 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15788292 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11896339 — Surrogate Endpoint (SUR): Blood pressure
Study 28275807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24673738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24673738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17109475 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 16047465 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2257871 — Surrogate Endpoint (SUR): Blood pressure
Study 549537 — Surrogate Endpoint (SUR): Blood pressure
Study 25217122 — Safety Biomarker (SAF): Hyaluronic acid
Study 10676721 — Surrogate Endpoint (SUR): Serum creatinine
Study 10676721 — Surrogate Endpoint (SUR): Bone mineral density
Study 29731164 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11710756 — Surrogate Endpoint (SUR): Blood pressure
Study 25393287 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 25393287 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23559084 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23559084 — Surrogate Endpoint (SUR): Blood pressure
Study 23559084 — Surrogate Endpoint (SUR): Urine free cortisol
Study 16269634 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH