TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24165545 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 19056646 — Surrogate Endpoint (SUR): Blood pressure
Study 1540063 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16015049 — Surrogate Endpoint (SUR): Blood pressure
Study 10554688 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8918511 — Surrogate Endpoint (SUR): Blood pressure
Study 19464609 — Surrogate Endpoint (SUR): Blood pressure
Study 31680339 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 28558854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24216069 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21345849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12859262 — Surrogate Endpoint (SUR): Blood pressure
Study 27164714 — Surrogate Endpoint (SUR): Blood pressure
Study 15725351 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 15725351 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 12684919 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27276842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19153758 — Surrogate Endpoint (SUR): Blood pressure
Study 16984929 — Surrogate Endpoint (SUR): Blood pressure
Study 30738826 — Surrogate Endpoint (SUR): Blood pressure
Study 23168287 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19300114 — Surrogate Endpoint (SUR): Blood pressure
Study 9551128 — Surrogate Endpoint (SUR): Blood pressure
Study 2006658 — Surrogate Endpoint (SUR): Blood pressure
Study 29931594 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 25295771 — Surrogate Endpoint (SUR): Blood pressure
Study 8622024 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6130038 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30553916 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 30553916 — Safety Biomarker (SAF): DRD2
Study 24837794 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19892836 — Surrogate Endpoint (SUR): Blood pressure
Study 16195001 — Surrogate Endpoint (SUR): Plasma ammonia
Study 12035937 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 12035937 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 26955742 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22927836 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8589318 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 8589318 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 8589318 — Predictive Biomarker (PRD): IGFBP4 mRNA
Genes: IGFBP4; IBP4
Study 8823230 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 8823230 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3280317 — Surrogate Endpoint (SUR): Blood pressure
Study 19033260 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17079789 — Surrogate Endpoint (SUR): Blood pressure
Study 8846523 — Surrogate Endpoint (SUR): Serum calcium
Study 8846523 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31785093 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 29615058 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29615058 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23396375 — Predictive Biomarker (PRD): CDH3 mRNA
Genes: CDH3; CDHP
Study 21922361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21922361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2517009 — Surrogate Endpoint (SUR): Blood pressure
Study 26119844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16785331 — Surrogate Endpoint (SUR): Blood pressure
Study 16785331 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15280154 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15280154 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3103761 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3103761 — Surrogate Endpoint (SUR): Blood pressure
Study 31268376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6988914 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 28631923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24958362 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 20479483 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 8416561 — Surrogate Endpoint (SUR): Serum creatinine
Study 27438111 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): miR-124
Study 12392115 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12392115 — Surrogate Endpoint (SUR): Blood pressure
Study 14742357 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10670263 — Surrogate Endpoint (SUR): Blood pressure
Study 1821972 — Surrogate Endpoint (SUR): Blood pressure
Study 31864822 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30235727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22273590 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16251607 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9615912 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18786258 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 7537355 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 1974664 — Surrogate Endpoint (SUR): Blood pressure
Study 29333081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23816015 — Surrogate Endpoint (SUR): Blood pressure
Study 9065538 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27100726 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27100726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12869088 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29193093 — Predictive Biomarker (PRD): ACADM mRNA
Genes: ACADM
Study 29193093 — Predictive Biomarker (PRD): IRS2 mRNA
Genes: IRS2
Study 29193093 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 23656841 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 17239355 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 8174049 — Surrogate Endpoint (SUR): Serum calcium
Study 29540217 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28746231 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26439936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15754270 — Surrogate Endpoint (SUR): Blood pressure
Study 12618533 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29908688 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27703294 — Surrogate Endpoint (SUR): Blood pressure
Study 21029610 — Surrogate Endpoint (SUR): Bone mineral density
Study 7552519 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26943500 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12141723 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12141723 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12141723 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12141723 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 19538331 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 9117021 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 3731678 — Surrogate Endpoint (SUR): Blood pressure
Study 21862454 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14634543 — Surrogate Endpoint (SUR): Bone mineral density
Study 6343871 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16607076 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 19704158 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 26294364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22735432 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22735432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26471584 — Surrogate Endpoint (SUR): Blood pressure
Study 26471584 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19293413 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 19293413 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3731893 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 25880068 — Surrogate Endpoint (SUR): Blood pressure
Study 9771209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9771209 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 798195 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26263075 — Surrogate Endpoint (SUR): Blood pressure
Study 14739050 — Surrogate Endpoint (SUR): Blood pressure
Study 10669363 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9107443 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9107443 — Surrogate Endpoint (SUR): Blood pressure
Study 1315560 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30957391 — Surrogate Endpoint (SUR): Blood pressure
Study 26740254 — Surrogate Endpoint (SUR): Blood pressure
Study 26740254 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26740254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26740254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26740254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26740254 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26740254 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28199805 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21512825 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 14701900 — Surrogate Endpoint (SUR): Blood pressure
Study 9116271 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 30215735 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30053896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30053896 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 10683057 — Surrogate Endpoint (SUR): Serum testosterone
Study 15691793 — Surrogate Endpoint (SUR): Serum sodium
Study 29944706 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 26861865 — Surrogate Endpoint (SUR): Blood pressure
Study 9025819 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27489241 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 27489241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21644308 — Surrogate Endpoint (SUR): Bone mineral density
Study 10232502 — Surrogate Endpoint (SUR): Blood pressure
Study 26743587 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26743587 — Surrogate Endpoint (SUR): Blood pressure
Study 18614930 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23768003 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 17284748 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17284748 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28747642 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 28747642 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18642209 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18642209 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18642209 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16564940 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 16564940 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24370543 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9796842 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7713815 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 23918588 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 23918588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 22192511 — Predictive Biomarker (PRD): KIF6 mRNA
Genes: KIF6; C6orf102
Study 22192511 — Predictive Biomarker (PRD): TAS2R50 mRNA
Genes: TAS2R50
Study 22192511 — Predictive Biomarker (PRD): VAMP8 mRNA
Genes: VAMP8
Study 22192511 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10172365 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 30421455 — Surrogate Endpoint (SUR): Blood pressure
Study 28329092 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 28329092 — Predictive Biomarker (PRD): FUT2 mRNA
Genes: FUT2; SEC2
Study 22294255 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22294255 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22294255 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 22294255 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22294255 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19963031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19963031 — Surrogate Endpoint (SUR): Serum uric acid
Study 17496286 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7789048 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2189149 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7322959 — Surrogate Endpoint (SUR): Blood pressure
Study 27428710 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 27428710 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 24048773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12677302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1334283 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28987358 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17102570 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2824710 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 25908323 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 11094866 — Surrogate Endpoint (SUR): Blood pressure
Study 3830478 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 27417562 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27417562 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study 27417562 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19026036 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 19026036 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 11716647 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2258877 — Surrogate Endpoint (SUR): Blood pressure
Study 7368972 — Surrogate Endpoint (SUR): Blood pressure
Study 27118495 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30808022 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 25410068 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 18319308 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 15944847 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 12866746 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 12499333 — Surrogate Endpoint (SUR): Blood pressure
Study 10818325 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10818325 — Surrogate Endpoint (SUR): Blood pressure
Study 19404210 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 16894934 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16894934 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 11453879 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 11453879 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1416135 — Surrogate Endpoint (SUR): Blood pressure
Study 22809630 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17585664 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 2258876 — Surrogate Endpoint (SUR): Blood pressure
Study 2258876 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9590463 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9590463 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 29263150 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18798327 — Predictive Biomarker (PRD): MPG mRNA
Genes: MPG; AAG; ANPG; MID1
Study 18798327 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 16176058 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 1867232 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1867232 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3196530 — Surrogate Endpoint (SUR): Blood pressure
Study 3196530 — Surrogate Endpoint (SUR): Serum sodium
Study 28381266 — Surrogate Endpoint (SUR): Blood pressure
Study 18283176 — Safety Biomarker (SAF): Interleukin 12
Study 16626574 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16626574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19576927 — Surrogate Endpoint (SUR): Blood pressure
Study 14715853 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28726169 — Surrogate Endpoint (SUR): Blood pressure
Study 19339887 — Safety Biomarker (SAF): XRCC1
Genes: RCC
Study 11329233 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3122113 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29497290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29497290 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12508388 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 10533691 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 7009424 — Surrogate Endpoint (SUR): Blood pressure
Study 24037492 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17355215 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15825717 — Surrogate Endpoint (SUR): Blood pressure
Study 8944409 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 1742482 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1742482 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1742482 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12010339 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 8580277 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30967395 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29747616 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 29747616 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 29747616 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19292590 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3360270 — Surrogate Endpoint (SUR): Serum sodium
Study 31599692 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 31599692 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 31599692 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 31599692 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31599692 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29132458 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26331821 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12840625 — Surrogate Endpoint (SUR): Blood pressure
Study 12840625 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10488604 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2052631 — Surrogate Endpoint (SUR): Blood pressure
Study 6315775 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 6315775 — Surrogate Endpoint (SUR): Serum testosterone
Study 9509971 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF