TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30587933 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30587933 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24864125 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24864125 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17659194 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12657846 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25226307 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24395497 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 21465244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27609756 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3001149 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19758824 — Surrogate Endpoint (SUR): Serum calcium
Study 15658649 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9950305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7522017 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7522017 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1090174 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 31977668 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 2349253 — Surrogate Endpoint (SUR): Blood pressure
Study 25366969 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25366969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25366969 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 17763150 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2642633 — Surrogate Endpoint (SUR): Blood pressure
Study 25085960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22520932 — Surrogate Endpoint (SUR): Blood pressure
Study 20170329 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21478216 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11294919 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9466166 — Surrogate Endpoint (SUR): Blood pressure
Study 19138237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19138237 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8964127 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1749827 — Predictive Biomarker (PRD): PHLPP1 mRNA
Genes: PHLPP1; KIAA0606; PHLPP; PLEKHE1; SCOP
Study 1749827 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 19403955 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 6507339 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25559834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25559834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22763666 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 16195625 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 2288318 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26184850 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21866658 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16624928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8268901 — Surrogate Endpoint (SUR): Blood pressure
Study 19729583 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 8068949 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28848332 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 23299909 — Surrogate Endpoint (SUR): Bone mineral density
Study 9371351 — Surrogate Endpoint (SUR): Serum creatinine
Study 23299370 — Surrogate Endpoint (SUR): Bone mineral density
Study 23299370 — Surrogate Endpoint (SUR): Blood pressure
Study 21426558 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 18957933 — Predictive Biomarker (PRD): IGFBP5 mRNA
Genes: IGFBP5; IBP5
Study 2955955 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15894770 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 6671816 — Surrogate Endpoint (SUR): Blood pressure
Study 31235103 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31235103 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18375321 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 18375321 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7117680 — Surrogate Endpoint (SUR): Blood pressure
Study 7117680 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 16326293 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27655859 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25194079 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 25194079 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 25194079 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 19844234 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19844234 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 19844234 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 17142202 — Surrogate Endpoint (SUR): Blood pressure
Study 1991894 — Surrogate Endpoint (SUR): Serum creatinine
Study 29777663 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 25722221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24325472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24325472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24325472 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30604559 — Surrogate Endpoint (SUR): Blood pressure
Study 15291683 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15291683 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 15291683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15291683 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 282097 — Surrogate Endpoint (SUR): Blood pressure
Study 31293100 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 23542532 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19734379 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 2065846 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2065846 — Surrogate Endpoint (SUR): Blood pressure
Study 31573608 — Surrogate Endpoint (SUR): Bone mineral density
Study 28669071 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 24927639 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 24927639 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 2058846 — Surrogate Endpoint (SUR): Blood pressure
Study 27825334 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20675411 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31472003 — Surrogate Endpoint (SUR): Serum calcium
Study 31472003 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 24054398 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 20933466 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 28700832 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28700832 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8616834 — Predictive Biomarker (PRD): GSTM3 mRNA
Genes: GSTM3; GST5
Study 8616834 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 8616834 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 8616834 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 1611985 — Surrogate Endpoint (SUR): Blood pressure
Study 720774 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28154331 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15823510 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 9798656 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 9798656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26077038 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 8550052 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 1405579 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1405579 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 2865188 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 29426869 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25463149 — Surrogate Endpoint (SUR): Blood pressure
Study 19703826 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 3968295 — Surrogate Endpoint (SUR): Blood pressure
Study 16563251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16563251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11867945 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10087460 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30125346 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25968575 — Predictive Biomarker (PRD): MKNK1 mRNA
Genes: MKNK1; MNK1
Study 25968575 — Predictive Biomarker (PRD): UBTF mRNA
Genes: UBTF; UBF; UBF1
Study 19965324 — Surrogate Endpoint (SUR): Serum creatinine
Study 17768273 — Predictive Biomarker (PRD): CHRNA4 mRNA
Genes: CHRNA4; NACRA4
Study 15347371 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8617150 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 10402091 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 2147537 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 31142526 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 31142526 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 31142526 — Surrogate Endpoint (SUR): Blood pressure
Study 20393694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20393694 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12730341 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12730341 — Surrogate Endpoint (SUR): Blood pressure
Study 10589859 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16298373 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29264967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24809437 — Surrogate Endpoint (SUR): Blood pressure
Study 23425082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19059539 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19059539 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19059539 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 15071489 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24036971 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18560537 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 18560537 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30380357 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30380357 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20805984 — Surrogate Endpoint (SUR): Blood pressure
Study 22525912 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 15886753 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 15886753 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 12585097 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31400480 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 31400480 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 31400480 — Safety Biomarker (SAF): miR-206
Genes: MIR206
Study 31400480 — Predictive Biomarker (PRD): miR-145
Genes: MIR145
Study 31400480 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-143
Genes: MIR143
Study 31400480 — Safety Biomarker (SAF): miR-9
Study 31400480 — Safety Biomarker (SAF): let-7a
Study 19850682 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 30529883 — Surrogate Endpoint (SUR): Blood pressure
Study 27217410 — Surrogate Endpoint (SUR): Blood pressure
Study 22673023 — Surrogate Endpoint (SUR): Serum sodium
Study 22673023 — Surrogate Endpoint (SUR): Serum creatinine
Study 22673023 — Surrogate Endpoint (SUR): Blood pressure
Study 3676232 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29861225 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 23930204 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 23930204 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23930204 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 23930204 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23930204 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23930204 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 16557041 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9816888 — Safety Biomarker (SAF): Reactive oxygen species
Study 22324425 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16007279 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 10638388 — Surrogate Endpoint (SUR): Blood pressure
Study 18625672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6124991 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 16258098 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12011969 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27084825 — Surrogate Endpoint (SUR): Blood pressure
Study 24670356 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 24670356 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 16931161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27101805 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 23947143 — Predictive Biomarker (PRD): miR-135a
Study 23947143 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): miR-124
Study 11475343 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11475343 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9721974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9721974 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2451135 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 26153496 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26153496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 26153496 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 27276234 — Surrogate Endpoint (SUR): Blood pressure
Study 22753922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 22753922 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15856068 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29032175 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25534375 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25534375 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 25534375 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 25534375 — Predictive Biomarker (PRD): CD8A mRNA
Genes: CD8A; MAL
Study 25534375 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 25534375 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 25534375 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 25534375 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 25534375 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 17097811 — Surrogate Endpoint (SUR): Blood pressure
Study 8438744 — Surrogate Endpoint (SUR): Blood pressure
Study 8438744 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8287661 — Surrogate Endpoint (SUR): Blood pressure
Study 18664620 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16650135 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 11016911 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11016911 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11016911 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29961295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29961295 — Surrogate Endpoint (SUR): Serum creatinine
Study 17978594 — Surrogate Endpoint (SUR): Blood pressure
Study 10819474 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 10819474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18773604 — Surrogate Endpoint (SUR): Blood pressure
Study 8907672 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 8907672 — Safety Biomarker (SAF): Reactive oxygen species
Study 25953020 — Surrogate Endpoint (SUR): Blood pressure
Study 25953020 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21252259 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21252259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21252259 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12544447 — Surrogate Endpoint (SUR): Blood pressure
Study 22425057 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 16279153 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 11985939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11985939 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11985939 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 24556493 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22465116 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22465116 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 22465116 — Surrogate Endpoint (SUR): Blood pressure
Study 1827053 — Surrogate Endpoint (SUR): Blood pressure
Study 24770960 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 12072587 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12072587 — Surrogate Endpoint (SUR): Blood pressure
Study 26547414 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 23340303 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23340303 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23340303 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23340303 — Predictive Biomarker (PRD): Hormone receptor
Study 10730729 — Surrogate Endpoint (SUR): Blood pressure
Study 31183384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31183384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7884326 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 26311750 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 14735295 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 11103798 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 11103798 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9197929 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 9197929 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 9197929 — Predictive Biomarker (PRD): SERPINF2 mRNA
Genes: SERPINF2; AAP; PLI
Study 9197929 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 9197929 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 2991832 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2991832 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18812733 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10972371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9117012 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24200249 — Surrogate Endpoint (SUR): Blood pressure
Study 19142480 — Surrogate Endpoint (SUR): Blood pressure
Study 14974909 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12458987 — Surrogate Endpoint (SUR): Bone mineral density
Study 1914056 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29116394 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP