TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20978279 — Surrogate Endpoint (SUR): Serum creatinine
Study 15658548 — Surrogate Endpoint (SUR): Bone mineral density
Study 11293926 — Surrogate Endpoint (SUR): Serum calcium
Study 12960596 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 10726910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10726910 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27503288 — Predictive Biomarker (PRD): GTF2I mRNA
Genes: GTF2I; BAP135; WBSCR6
Study 18550508 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 16117995 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30008787 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 30008787 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30008787 — Safety Biomarker (SAF): Reactive oxygen species
Study 11246064 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21291529 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21291529 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21291529 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 1784628 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 6177276 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 22052170 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 15769772 — Surrogate Endpoint (SUR): Blood pressure
Study 21138376 — Surrogate Endpoint (SUR): Blood pressure
Study 11866010 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11866010 — Surrogate Endpoint (SUR): Serum potassium
Study 11866010 — Surrogate Endpoint (SUR): Serum creatinine
Study 9674473 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 24684534 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 23090102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23090102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14969841 — Monitoring Biomarker (MOI): HBV DNA
Study 9205679 — Surrogate Endpoint (SUR): Blood pressure
Study 14628939 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 14628939 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 14628939 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 31883278 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24389518 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 20012918 — Surrogate Endpoint (SUR): Bone mineral density
Study 26691355 — Surrogate Endpoint (SUR): Blood pressure
Study 9767545 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9767545 — Surrogate Endpoint (SUR): Blood pressure
Study 8162670 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 15015143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15015143 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7691911 — Surrogate Endpoint (SUR): Blood pressure
Study 28423234 — Surrogate Endpoint (SUR): Blood pressure
Study 21042828 — Surrogate Endpoint (SUR): Serum creatinine
Study 19901841 — Surrogate Endpoint (SUR): Blood pressure
Study 11955536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 558950 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 23545667 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 21464406 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21464406 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18511076 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18511076 — Safety Biomarker (SAF): BDNF
Study 16670691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16670691 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 16670691 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16670691 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16670691 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8043708 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 29654929 — Surrogate Endpoint (SUR): Blood pressure
Study 22420423 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study 22420423 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 22420423 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 20216467 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 20216467 — Predictive Biomarker (PRD): MYOD1 mRNA
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 20216467 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 17496307 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15774702 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15774702 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 7552531 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6871070 — Surrogate Endpoint (SUR): Blood pressure
Study 29866129 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 22274317 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 22274317 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 19179905 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 2031796 — Surrogate Endpoint (SUR): Blood pressure
Study 25424715 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 18542850 — Surrogate Endpoint (SUR): Blood pressure
Study 15170977 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15170977 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12752559 — Surrogate Endpoint (SUR): Blood pressure
Study 7675920 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19889469 — Surrogate Endpoint (SUR): Serum creatinine
Study 12297918 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 29142294 — Surrogate Endpoint (SUR): Serum testosterone
Study 29142294 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 23006479 — Surrogate Endpoint (SUR): Blood pressure
Study 20339913 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11821453 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8455371 — Safety Biomarker (SAF): Interleukin 1
Study 25676405 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25676405 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 10664922 — Surrogate Endpoint (SUR): Blood pressure
Study 30364350 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 16198932 — Surrogate Endpoint (SUR): Blood pressure
Study 21327794 — Surrogate Endpoint (SUR): Serum testosterone
Study 7857761 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29019886 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 30287607 — Surrogate Endpoint (SUR): Serum creatinine
Study 27646578 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 27646578 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 20724342 — Surrogate Endpoint (SUR): Blood pressure
Study 10091520 — Surrogate Endpoint (SUR): Blood pressure
Study 1670840 — Surrogate Endpoint (SUR): Serum calcium
Study 26663215 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 22320349 — Surrogate Endpoint (SUR): Blood pressure
Study 8729740 — Predictive Biomarker (PRD): AHSP mRNA
Genes: AHSP; EDRF; ERAF
Study 8729740 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 8729740 — Surrogate Endpoint (SUR): Blood pressure
Study 30429438 — Surrogate Endpoint (SUR): Bacterial count
Study 26856345 — Surrogate Endpoint (SUR): Serum potassium
Study 20851080 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16372586 — Surrogate Endpoint (SUR): Serum creatinine
Study 16372586 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29484209 — Surrogate Endpoint (SUR): Blood pressure
Study 19013463 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16815651 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10669280 — Surrogate Endpoint (SUR): Blood pressure
Study 29323617 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 10767227 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9549298 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19189603 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 29338113 — Surrogate Endpoint (SUR): Blood pressure
Study 15358690 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 7525192 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23728830 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23728830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23728830 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30081009 — Surrogate Endpoint (SUR): Blood pressure
Study 30081009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24517055 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24517055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19853906 — Surrogate Endpoint (SUR): Blood pressure
Study 31385180 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 11605012 — Predictive Biomarker (PRD): Hormone receptor
Study 24895097 — Surrogate Endpoint (SUR): Blood pressure
Study 24895097 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12460133 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 10466460 — Surrogate Endpoint (SUR): Blood pressure
Study 2024858 — Surrogate Endpoint (SUR): Serum creatinine
Study 26755593 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10521751 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7195642 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 22706571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22706571 — Safety Biomarker (SAF): Reactive oxygen species
Study 22706571 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 22706571 — Safety Biomarker (SAF): IL-6 and IL-10
Study 20130877 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20130877 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 20130877 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20130877 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 20130877 — Predictive Biomarker (PRD): MET
Genes: HGFR; RCCP2; DFNB97
Study 20130877 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 10608543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1851068 — Surrogate Endpoint (SUR): Blood pressure
Study 26291817 — Surrogate Endpoint (SUR): Sperm parameters
Study 17923867 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12496748 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9818309 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 7516001 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7516001 — Surrogate Endpoint (SUR): Blood pressure
Study 29706210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10673519 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 8790153 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 7969680 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 7969680 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28131081 — Predictive Biomarker (PRD): GMCL2 mRNA
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 21957976 — Surrogate Endpoint (SUR): Blood pressure
Study 18781668 — Surrogate Endpoint (SUR): Blood pressure
Study 16680067 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 19303575 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9562230 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 9562230 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2689182 — Surrogate Endpoint (SUR): Serum creatinine
Study 2689182 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30952672 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 23429358 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21148683 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 7679869 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31848562 — Predictive Biomarker (PRD): LCN1 mRNA
Genes: LCN1; VEGP
Study 31848562 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31848562 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27473139 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 7486089 — Surrogate Endpoint (SUR): Blood pressure
Study 20137493 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11426771 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 11426771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11426771 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9714133 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 9714133 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9714133 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30260990 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 22932264 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 8267064 — Surrogate Endpoint (SUR): Blood pressure
Study 12356630 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 31553228 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 22241923 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24368558 — Surrogate Endpoint (SUR): Blood pressure
Study 15383007 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 15383007 — Surrogate Endpoint (SUR): Blood pressure
Study 2672925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30747908 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 12593029 — Predictive Biomarker (PRD): BGN mRNA
Genes: BGN; SLRR1A
Study 2642543 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 23739758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10424402 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 499311 — Surrogate Endpoint (SUR): Blood pressure
Study 31022754 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31022754 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31022754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29460813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26790758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20642382 — Surrogate Endpoint (SUR): Blood pressure
Study 18045691 — Predictive Biomarker (PRD): TPSG1 mRNA
Genes: TPSG1; PRSS31; TMT
Study 9093710 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29610265 — Surrogate Endpoint (SUR): Blood pressure
Study 20080466 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study 20080466 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20080466 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 16500773 — Surrogate Endpoint (SUR): Blood pressure
Study 14711911 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11717598 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20955281 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16282543 — Predictive Biomarker (PRD): PCK1 mRNA
Genes: PCK1; PEPCK1
Study 19768533 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 16344838 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 10085709 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 25435541 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25435541 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 22960949 — Predictive Biomarker (PRD): MST1R mRNA
Genes: MST1R; PTK8; RON
Study 21990403 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16352871 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 11294367 — Surrogate Endpoint (SUR): Blood pressure
Study 11294367 — Surrogate Endpoint (SUR): Serum potassium
Study 24706266 — Predictive Biomarker (PRD): HPX mRNA
Genes: HPX
Study 9507380 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3376912 — Surrogate Endpoint (SUR): Blood pressure
Study 26659915 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 20647201 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11809343 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2225706 — Surrogate Endpoint (SUR): Bone mineral density
Study 30357395 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 30357395 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 30357395 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 30357395 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 22227183 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15740939 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7731378 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24321380 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24321380 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19542983 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17479606 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 17479606 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11756910 — Surrogate Endpoint (SUR): Blood pressure
Study 29704940 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9788977 — Surrogate Endpoint (SUR): Bone mineral density
Study 30919407 — Predictive Biomarker (PRD): SELE mRNA
Genes: SELE; ELAM1
Study 28929697 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 22112606 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 22112606 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 22112606 — Surrogate Endpoint (SUR): Bone mineral density
Study 7992905 — Surrogate Endpoint (SUR): Blood pressure
Study 22695137 — Surrogate Endpoint (SUR): Blood pressure
Study 19394478 — Surrogate Endpoint (SUR): Bone mineral density
Study 24827123 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 24827123 — Predictive Biomarker (PRD): HES1 mRNA
Genes: HES1; BHLHB39; HL; HRY
Study 24827123 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24827123 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 22541840 — Surrogate Endpoint (SUR): Blood pressure
Study 12948801 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 18716159 — Surrogate Endpoint (SUR): Serum uric acid
Study 18716159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30946887 — Predictive Biomarker (PRD): RNPC3 mRNA
Genes: RNPC3; KIAA1839; RBM40; RNP; SNRNP65
Study 28029326 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 16268981 — Surrogate Endpoint (SUR): Blood pressure
Study 22445212 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 17494789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26059264 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21439275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1477649 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30686751 — Predictive Biomarker (PRD): IL7 mRNA
Genes: IL7
Study 20417038 — Surrogate Endpoint (SUR): Blood pressure
Study 14699490 — Monitoring Biomarker (MOI): HBV DNA
Study 28878437 — Surrogate Endpoint (SUR): Blood pressure
Study 26836126 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 24655119 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17884351 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 30670438 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 30670438 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 30670438 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 30670438 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 11948033 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21425571 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4