TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03737799 — Predictive Biomarker (PRD): SCPEP1 mRNA
Genes: SCPEP1; RISC; SCP1; MSTP034; UNQ265/PRO302
Study NCT01729598 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT03014219 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03262974 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT03262974 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT03262974 — Predictive Biomarker (PRD): SLC22A1 mRNA
Genes: SLC22A1; OCT1
Study NCT00003190 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04143087 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04143087 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01097915 — Predictive Biomarker (PRD): CA6 mRNA
Genes: CA6
Study NCT02920164 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03561350 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT03561350 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00200161 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03117972 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT00612222 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02534584 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03318900 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT00776724 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02840773 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT05345366 — Predictive Biomarker (PRD): CITED2 mRNA
Genes: CITED2; MRG1
Study NCT05345366 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05345366 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT05345366 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02797145 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01678443 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT00005788 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01478113 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study NCT04098796 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT03781089 — Surrogate Endpoint (SUR): Serum potassium
Study NCT03672643 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03672643 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT04430192 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00240968 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02561546 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00420719 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00576524 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04238052 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00383604 — Predictive Biomarker (PRD): FOXC2 mRNA
Genes: FOXC2; FKHL14; MFH1
Study NCT04156243 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04300647 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00118625 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT00742820 — Surrogate Endpoint (SUR): Serum calcium
Study NCT00634400 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00437892 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03300050 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05253560 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT03431584 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00796185 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00796185 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00796185 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT04439175 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04289701 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03056664 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03601156 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02597868 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02597868 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02597868 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02556827 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study NCT02556827 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study NCT04467931 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04467931 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02199821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00774358 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00409786 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02974348 — Predictive Biomarker (PRD): LUM mRNA
Genes: LUM; LDC; SLRR2D
Study NCT01681017 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study NCT01057823 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03792542 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT03792542 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03792542 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT03463525 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00335686 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT01598727 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT02187705 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02444104 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02043301 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02259556 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT02470039 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04482608 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT02213042 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02213042 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03793556 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01133210 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT02840240 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04642170 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT01959386 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02682407 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT00258284 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT00608972 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01042392 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00103662 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00006156 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02976246 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT02976246 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04612582 — Predictive Biomarker (PRD): BTD mRNA
Genes: BTD
Study NCT03388515 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00339404 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT00339404 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT01033721 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02470416 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT02470416 — Predictive Biomarker (PRD): STK11 mRNA
Genes: STK11; LKB1; PJS
Study NCT04261660 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04261660 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03709082 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03709082 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02738632 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00898794 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01001169 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01683617 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03064542 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT01633827 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03806517 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06433843 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study NCT00277446 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00185068 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03157635 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT02759484 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01030913 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT01504243 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT02123173 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00477906 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01400815 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT01400815 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01192373 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02292199 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03181815 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02664610 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02605785 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04390061 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT01140373 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04475211 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03987776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03987776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00575068 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT02790918 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02790918 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00003750 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03038451 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02606045 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03825523 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04375618 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01803152 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00757913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02928120 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02928120 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02066220 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02066220 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study NCT02269046 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00828854 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03513497 — Predictive Biomarker (PRD): IFI16 mRNA
Genes: IFI16; IFNGIP1
Study NCT03513497 — Predictive Biomarker (PRD): AIM2 mRNA
Genes: AIM2
Study NCT01021579 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01369160 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT01369160 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01469624 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02233621 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT02233621 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04391179 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04323228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04323228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04323228 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT04323228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04323228 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT01995344 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00632073 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT04663373 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04663373 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04394611 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT04394611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03026829 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT02128906 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT03473951 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00814866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04104958 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01838902 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT01856907 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04074031 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT04439344 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT04439344 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT04439344 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study NCT04553081 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04473261 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01050491 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT00071396 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT02935296 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00791037 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02031211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03452228 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study NCT03452228 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03240198 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT03240198 — Predictive Biomarker (PRD): AIF1 mRNA
Genes: AIF1; G1; IBA1
Study NCT03240198 — Predictive Biomarker (PRD): HCG22 mRNA
Genes: HCG22; G2; PBMUCL2
Study NCT03240198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02264210 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02264210 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04057365 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT03497533 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04371809 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01484236 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT00597389 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00698984 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00769704 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02850354 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02378532 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02378532 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03864523 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT03864523 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study NCT04154215 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00002746 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02929693 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02979795 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01705808 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT00467857 — Surrogate Endpoint (SUR): Bacterial count
Study NCT04459546 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT01146132 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02623920 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT02282358 — Predictive Biomarker (PRD): CREBBP mRNA
Genes: CREBBP; CBP
Study NCT02282358 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT00202059 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00308425 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03857113 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00540449 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00309478 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03524677 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT03524677 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study NCT03524677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT03408678 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01748019 — Pharmacodynamic Biomarker (PDY): DNA topoisomerase I
Genes: TOP1
Study NCT04118842 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00211484 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03155347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02176681 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02069106 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00282685 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study NCT04262011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03752541 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT01038284 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01673009 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT03218293 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03218293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01628172 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03040908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03040908 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01736124 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02634749 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04966052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03495427 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03495427 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT04394845 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00762801 — Predictive Biomarker (PRD): RALBP1 mRNA
Genes: RALBP1; RLIP; RLIP1; RLIP76
Study NCT02433288 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02891031 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00277979 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT01381874 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04114747 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00487838 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT06702930 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02207023 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02177955 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03848442 — Predictive Biomarker (PRD): MECP2 mRNA
Genes: MECP2
Study NCT01834118 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02710071 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05073640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04351997 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study NCT02723448 — Predictive Biomarker (PRD): TREX1 mRNA
Genes: TREX1
Study NCT03109626 — Predictive Biomarker (PRD): ELOVL5 mRNA
Genes: ELOVL5; ELOVL2; PRO0530
Study NCT01475409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00000519 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00051389 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01034033 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01034033 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02011425 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS