TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25185831 — Surrogate Endpoint (SUR): Blood pressure
Study 18027125 — Surrogate Endpoint (SUR): Blood pressure
Study 7599866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2347435 — Surrogate Endpoint (SUR): Blood pressure
Study 117999 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 20228421 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 18307459 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15987919 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8853810 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8853810 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1535185 — Surrogate Endpoint (SUR): Blood pressure
Study 27325467 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7703634 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29512900 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 29512900 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24299932 — Surrogate Endpoint (SUR): Blood pressure
Study 22552863 — Surrogate Endpoint (SUR): Blood pressure
Study 20371662 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20371662 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 1950061 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 11787023 — Safety Biomarker (SAF): Hyaluronic acid
Study 19356868 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19356868 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11595622 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 11595622 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29040223 — Surrogate Endpoint (SUR): Blood pressure
Study 26869286 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 26869286 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 17872493 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 31466764 — Surrogate Endpoint (SUR): Blood pressure
Study 24096616 — Surrogate Endpoint (SUR): Blood pressure
Study 9390667 — Predictive Biomarker (PRD): PCLO mRNA
Genes: PCLO; ACZ; KIAA0559
Study 7942524 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26387039 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25311217 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 25311217 — Surrogate Endpoint (SUR): Serum testosterone
Study 15317320 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 21938543 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18301136 — Surrogate Endpoint (SUR): Serum creatinine
Study 29579601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2931515 — Predictive Biomarker (PRD): PTGDS mRNA
Genes: PTGDS; PDS
Study 2931988 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2931988 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16437190 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 8868976 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8868976 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31850717 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study 21551161 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21551161 — Surrogate Endpoint (SUR): Blood pressure
Study 12225339 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 7832598 — Surrogate Endpoint (SUR): Forced vital capacity
Study 417957 — Surrogate Endpoint (SUR): Blood pressure
Study 21501161 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19700872 — Surrogate Endpoint (SUR): Blood pressure
Study 24860180 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26036956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26036956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26036956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24434439 — Predictive Biomarker (PRD): PDCD4 mRNA
Genes: PDCD4; H731
Study 24434439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24434439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12204869 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30769227 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29226773 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29226773 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10333052 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10333052 — Surrogate Endpoint (SUR): Blood pressure
Study 8095058 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8095058 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3530649 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11471363 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8050422 — Surrogate Endpoint (SUR): Blood pressure
Study 3184782 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31242752 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 28032482 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 23537419 — Surrogate Endpoint (SUR): Blood pressure
Study 22047812 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 9312760 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9312760 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 8349825 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 2872813 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26231610 — Surrogate Endpoint (SUR): Blood pressure
Study 26231610 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11077134 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11077134 — Surrogate Endpoint (SUR): Blood pressure
Study 28454835 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28454835 — Surrogate Endpoint (SUR): Serum potassium
Study 24159603 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24159603 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24159603 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 24159603 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 21390311 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 14530465 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 12578881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3469101 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 10686040 — Surrogate Endpoint (SUR): Blood pressure
Study 31518482 — Monitoring Biomarker (MOI): HBV DNA
Study 12563203 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30930022 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30930022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30930022 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30930022 — Monitoring Biomarker (MOI): HBV DNA
Study 28507171 — Predictive Biomarker (PRD): SLC12A1 mRNA
Genes: SLC12A1; NKCC2
Study 25252699 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23897954 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23897954 — Predictive Biomarker (PRD): Hormone receptor
Study 23897954 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 16552540 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 16552540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12940503 — Surrogate Endpoint (SUR): Blood pressure
Study 9020562 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 24559642 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 27631316 — Predictive Biomarker (PRD): RIT1 mRNA
Genes: RIT1; RIBB; RIT; ROC1
Study 24098434 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24098434 — Surrogate Endpoint (SUR): Blood pressure
Study 31728713 — Surrogate Endpoint (SUR): Blood pressure
Study 20061355 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20061355 — Surrogate Endpoint (SUR): Blood pressure
Study 18322300 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 12204809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8631045 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8631045 — Surrogate Endpoint (SUR): Blood pressure
Study 1671389 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29979711 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 27321488 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27321488 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 27321488 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27321488 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 19497591 — Surrogate Endpoint (SUR): Blood pressure
Study 15700851 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 12704264 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 18632766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18632766 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 4009494 — Surrogate Endpoint (SUR): Blood pressure
Study 17345556 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7706611 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7706611 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2198233 — Surrogate Endpoint (SUR): Blood pressure
Study 30412478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26475844 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26475844 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27172269 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 26346433 — Surrogate Endpoint (SUR): Blood pressure
Study 17268408 — Surrogate Endpoint (SUR): Blood pressure
Study 23170990 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21600058 — Surrogate Endpoint (SUR): Blood pressure
Study 16463153 — Safety Biomarker (SAF): MTHFR
Study 1614041 — Surrogate Endpoint (SUR): Serum creatinine
Study 29771789 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23107042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23107042 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23107042 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23107042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18408707 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18408707 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15838067 — Surrogate Endpoint (SUR): Blood pressure
Study 15838067 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31272251 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 26008138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 29247149 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 27872513 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 27872513 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 9598837 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7895227 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 28798089 — Surrogate Endpoint (SUR): Blood pressure
Study 23924586 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23924586 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20625394 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 19138933 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study 19138933 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 19138933 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 19138933 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16380297 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30400977 — Surrogate Endpoint (SUR): Blood pressure
Study 18476430 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15546907 — Surrogate Endpoint (SUR): Bone mineral density
Study 28124206 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28124206 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26032168 — Safety Biomarker (SAF): CYP2D6
Genes: CPD6; P450-DB1; CYP2D; P450C2D
Study 11968154 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 11968154 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9893888 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 580588 — Surrogate Endpoint (SUR): Blood pressure
Study 21954280 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 19184101 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17143257 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17143257 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17143257 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 14656690 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 14656690 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 14656690 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 1284161 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 1284161 — Surrogate Endpoint (SUR): Blood pressure
Study 26959690 — Predictive Biomarker (PRD): KCNIP4 mRNA
Genes: KCNIP4; CALP; KCHIP4
Study 17313717 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 11405491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8313331 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3416497 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31618328 — Predictive Biomarker (PRD): SREBF1 mRNA
Genes: SREBF1; BHLHD1; SREBP1
Study 9738724 — Surrogate Endpoint (SUR): Blood pressure
Study 27722974 — Surrogate Endpoint (SUR): Blood pressure
Study 23084280 — Surrogate Endpoint (SUR): Blood pressure
Study 16042771 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8694167 — Surrogate Endpoint (SUR): Blood pressure
Study 29393137 — Surrogate Endpoint (SUR): Serum uric acid
Study 27875567 — Surrogate Endpoint (SUR): Blood pressure
Study 20375690 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 16094389 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 11880822 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10429496 — Safety Biomarker (SAF): Hyaluronic acid
Study 31972599 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 28102697 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 9431481 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 25947649 — Surrogate Endpoint (SUR): Blood pressure
Study 9483409 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 31360702 — Surrogate Endpoint (SUR): Blood pressure
Study 22363616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22363616 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22363616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18843118 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15879919 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15879919 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15879919 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15879919 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2058572 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2058572 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15698450 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11960607 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7653482 — Surrogate Endpoint (SUR): Bone mineral density
Study 7653482 — Surrogate Endpoint (SUR): Serum calcium
Study 2510348 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20373478 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 7024157 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 26497691 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 28681218 — Surrogate Endpoint (SUR): Pathological complete response
Study 24720402 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 17200765 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17200765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16083710 — Monitoring Biomarker (MOI): HBV DNA
Study 10721440 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23399350 — Surrogate Endpoint (SUR): Blood pressure
Study 23399350 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23399350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20449933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15033248 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 15033248 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2470995 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2470995 — Surrogate Endpoint (SUR): Blood pressure
Study 19488583 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10661480 — Surrogate Endpoint (SUR): Blood pressure
Study 31424631 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 29465059 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 24074810 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24074810 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 21959825 — Surrogate Endpoint (SUR): Serum uric acid
Study 16841795 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30563934 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 17950096 — Surrogate Endpoint (SUR): Blood pressure
Study 17950096 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17950096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17950096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12241530 — Surrogate Endpoint (SUR): Blood pressure
Study 10404801 — Surrogate Endpoint (SUR): Bone mineral density
Study 12215470 — Surrogate Endpoint (SUR): Blood pressure
Study 30400588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 30400588 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30400588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7574954 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7438715 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7438715 — Surrogate Endpoint (SUR): Blood pressure
Study 30977273 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 12393618 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 2857601 — Surrogate Endpoint (SUR): Blood pressure
Study 26745614 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 20182883 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 19087677 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7473519 — Surrogate Endpoint (SUR): Blood pressure
Study 27589995 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22345689 — Surrogate Endpoint (SUR): Blood pressure
Study 2986300 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2986300 — Surrogate Endpoint (SUR): Blood pressure
Study 15155718 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 11593092 — Surrogate Endpoint (SUR): Blood pressure
Study 11593092 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9638417 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 25425015 — Surrogate Endpoint (SUR): Blood pressure
Study 24133618 — Surrogate Endpoint (SUR): Blood pressure
Study 20031845 — Surrogate Endpoint (SUR): Blood pressure
Study 16678643 — Surrogate Endpoint (SUR): Serum creatinine
Study 15379423 — Predictive Biomarker (PRD): FOXH1 mRNA
Genes: FOXH1; FAST1; FAST2
Study 11179329 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11179329 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12773674 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 31288213 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28079606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2