TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8549061 — Surrogate Endpoint (SUR): Blood pressure
Study 19756431 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 17622361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17622361 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17622361 — Safety Biomarker (SAF): Reactive oxygen species
Study 11888836 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31378863 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 31378863 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28160355 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 26316042 — Surrogate Endpoint (SUR): Blood pressure
Study 19387901 — Surrogate Endpoint (SUR): Blood pressure
Study 19387901 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15293073 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 10426682 — Surrogate Endpoint (SUR): Blood pressure
Study 24189215 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19841453 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19841453 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28057081 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19697997 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19697997 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19697997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11314678 — Surrogate Endpoint (SUR): Blood pressure
Study 27723955 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31663368 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27544129 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 7619662 — Surrogate Endpoint (SUR): Blood pressure
Study 31102318 — Predictive Biomarker (PRD): WWC1 mRNA
Genes: WWC1; KIAA0869
Study 31102318 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31102318 — Predictive Biomarker (PRD): Hormone receptor
Study 29853785 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 29853785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19922664 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9794747 — Surrogate Endpoint (SUR): Blood pressure
Study 27782976 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 25565485 — Surrogate Endpoint (SUR): Blood pressure
Study 9193221 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27936949 — Surrogate Endpoint (SUR): Blood pressure
Study 31679079 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31679079 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 28027641 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17854593 — Surrogate Endpoint (SUR): Serum creatinine
Study 17854593 — Surrogate Endpoint (SUR): Serum sodium
Study 7803946 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7803946 — Surrogate Endpoint (SUR): Blood pressure
Study 2468858 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31790147 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23541416 — Predictive Biomarker (PRD): HOXA10 mRNA
Genes: HOXA10; HOX1H
Study 20716145 — Surrogate Endpoint (SUR): Blood pressure
Study 10423656 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10423656 — Surrogate Endpoint (SUR): Blood pressure
Study 10423656 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7421183 — Surrogate Endpoint (SUR): Blood pressure
Study 31430226 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15169685 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 11821367 — Surrogate Endpoint (SUR): Blood pressure
Study 9723827 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9723827 — Surrogate Endpoint (SUR): Blood pressure
Study 23736998 — Predictive Biomarker (PRD): TK1 mRNA
Genes: TK1
Study 15167287 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15167287 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9514180 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 7995312 — Surrogate Endpoint (SUR): Blood pressure
Study 30135733 — Surrogate Endpoint (SUR): Blood pressure
Study 26751191 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22067277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19293199 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16095444 — Predictive Biomarker (PRD): ARX mRNA
Genes: ARX
Study 27719741 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 28501556 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12937023 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 12937023 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9184737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1350481 — Surrogate Endpoint (SUR): Blood pressure
Study 4007027 — Surrogate Endpoint (SUR): Serum potassium
Study 19947861 — Predictive Biomarker (PRD): FOXH1 mRNA
Genes: FOXH1; FAST1; FAST2
Study 6424494 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11156038 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 27737744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27737744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24795254 — Predictive Biomarker (PRD): HSD11B1 mRNA
Genes: HSD11B1; HSD11; HSD11L; SDR26C1
Study 31904760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31904760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31904760 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 31904760 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31904760 — Safety Biomarker (SAF): Interleukin 1
Study 12706935 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 27113048 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10826403 — Surrogate Endpoint (SUR): Blood pressure
Study 21276961 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21276961 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12743670 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9337806 — Surrogate Endpoint (SUR): Blood pressure
Study 9179187 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 2859970 — Surrogate Endpoint (SUR): Blood pressure
Study 21790765 — Surrogate Endpoint (SUR): Blood pressure
Study 2939869 — Surrogate Endpoint (SUR): Blood pressure
Study 28252452 — Safety Biomarker (SAF): DRD2
Study 19048695 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 1677229 — Surrogate Endpoint (SUR): Blood pressure
Study 26768165 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31526640 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 30762726 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 28838955 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 28838955 — Surrogate Endpoint (SUR): Total kidney volume
Study 23782554 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 22462654 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30706798 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30706798 — Surrogate Endpoint (SUR): Blood pressure
Study 26166555 — Surrogate Endpoint (SUR): Blood pressure
Study 8884415 — Surrogate Endpoint (SUR): Blood pressure
Study 18413835 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1951126 — Surrogate Endpoint (SUR): Serum potassium
Study 1951126 — Surrogate Endpoint (SUR): Blood pressure
Study 22384545 — Surrogate Endpoint (SUR): Serum creatinine
Study 22384545 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 15470284 — Surrogate Endpoint (SUR): Blood pressure
Study 18829015 — Surrogate Endpoint (SUR): Sperm parameters
Study 11270020 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24109189 — Surrogate Endpoint (SUR): Blood pressure
Study 7687608 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 31992249 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 30403574 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30403574 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30403574 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18648200 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18648200 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 394864 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26367003 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26367003 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 26367003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11443567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11443567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11443567 — Safety Biomarker (SAF): Interleukin 1
Study 24371264 — Safety Biomarker (SAF): miR-133a
Study 24371264 — Safety Biomarker (SAF): miR-133b
Genes: MIR133B
Study 24371264 — Safety Biomarker (SAF): miR-1
Study 18341614 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FasL mRNA
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 30925824 — Surrogate Endpoint (SUR): Blood pressure
Study 27711199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27711199 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27711199 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27711199 — Surrogate Endpoint (SUR): Blood pressure
Study 1833042 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 1833042 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 1833042 — Predictive Biomarker (PRD): HMGXB3 mRNA
Genes: HMGXB3; KIAA0194; SMF
Study 26804640 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 26804640 — Surrogate Endpoint (SUR): Serum calcium
Study 17393237 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8036887 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31181564 — Predictive Biomarker (PRD): CA3 mRNA
Genes: CA3
Study 15889626 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study 2149512 — Surrogate Endpoint (SUR): Blood pressure
Study 25138548 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 25138548 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21254315 — Surrogate Endpoint (SUR): Blood pressure
Study 17212913 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 25558162 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25558162 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 16905079 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16905079 — Surrogate Endpoint (SUR): Blood pressure
Study 10676716 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 10676716 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 10676716 — Surrogate Endpoint (SUR): Serum creatinine
Study 10676716 — Surrogate Endpoint (SUR): Blood pressure
Study 24887106 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23315607 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 21821810 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15148063 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15148063 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27567493 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 19903864 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31948455 — Surrogate Endpoint (SUR): Bone mineral density
Study 28882233 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17002607 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 17002607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17002607 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10778871 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3952023 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20718734 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 16446690 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9666905 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 31174256 — Surrogate Endpoint (SUR): Blood pressure
Study 31174256 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28383476 — Surrogate Endpoint (SUR): Blood pressure
Study 26491119 — Predictive Biomarker (PRD): BCAR1 mRNA
Genes: BCAR1; CAS; CASS1; CRKAS
Study 29782181 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 27644566 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 24503114 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15659490 — Predictive Biomarker (PRD): Hormone receptor
Study 10194129 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30771560 — Surrogate Endpoint (SUR): Blood pressure
Study 10732308 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 26324180 — Predictive Biomarker (PRD): TXNIP mRNA
Genes: TXNIP; VDUP1
Study 18379010 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 18379010 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 22433473 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16208149 — Surrogate Endpoint (SUR): Blood pressure
Study 10411366 — Surrogate Endpoint (SUR): Blood pressure
Study 1443507 — Surrogate Endpoint (SUR): Blood pressure
Study 26865074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16159895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16159895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16159895 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16159895 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 9987642 — Surrogate Endpoint (SUR): Blood pressure
Study 27977637 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22253271 — Surrogate Endpoint (SUR): Blood pressure
Study 2809260 — Safety Biomarker (SAF): Interleukin 1
Study 2809260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15577415 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 406098 — Surrogate Endpoint (SUR): Blood pressure
Study 31299067 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28006055 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26097039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20716842 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 20716842 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15168720 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2780876 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 31180512 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 25468945 — Surrogate Endpoint (SUR): Blood pressure
Study 21795553 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21795553 — Safety Biomarker (SAF): BDNF
Study 11122838 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 11122838 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 11122838 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11122838 — Safety Biomarker (SAF): Interleukin 12
Study 28767552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15343354 — Surrogate Endpoint (SUR): Blood pressure
Study 10574584 — Surrogate Endpoint (SUR): Bone mineral density
Study 2156886 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2156886 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 538766 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 27806969 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19696660 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10475182 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 6175803 — Surrogate Endpoint (SUR): Blood pressure
Study 21898040 — Surrogate Endpoint (SUR): Serum creatinine
Study 18822413 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17996517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17996517 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17996517 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9614767 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31250285 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21241520 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 21241520 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 1740541 — Surrogate Endpoint (SUR): Blood pressure
Study 6377291 — Surrogate Endpoint (SUR): Blood pressure
Study 24823671 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11317199 — Surrogate Endpoint (SUR): Blood pressure
Study 9344701 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 9344701 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 26773777 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25262522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22475545 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1823905 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1823905 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1823905 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6119182 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6119182 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22010913 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17414228 — Surrogate Endpoint (SUR): Blood pressure
Study 11850771 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11850771 — Surrogate Endpoint (SUR): Blood pressure
Study 11850771 — Surrogate Endpoint (SUR): Serum uric acid
Study 11850771 — Surrogate Endpoint (SUR): Serum potassium
Study 31443226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17336181 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15181565 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15181565 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11352127 — Surrogate Endpoint (SUR): Blood pressure
Study 19231043 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 19231043 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16768834 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 16768834 — Surrogate Endpoint (SUR): Blood pressure
Study 16768834 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7451917 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 31060602 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 31060602 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 27794137 — Surrogate Endpoint (SUR): Blood pressure
Study 19293796 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16674782 — Surrogate Endpoint (SUR): Blood pressure
Study 15560811 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 11742907 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7973107 — Surrogate Endpoint (SUR): Serum potassium
Study 21247529 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 21247529 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21247529 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 2210808 — Surrogate Endpoint (SUR): Blood pressure
Study 6151553 — Surrogate Endpoint (SUR): Blood pressure
Study 31348732 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 20962312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20962312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20962312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2