TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12172954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2240504 — Surrogate Endpoint (SUR): Blood pressure
Study 10933100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8822346 — Surrogate Endpoint (SUR): Bone mineral density
Study 25509262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25509262 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25509262 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25509262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16259547 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 1829401 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6365468 — Surrogate Endpoint (SUR): Blood pressure
Study 30006778 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28835229 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28835229 — Surrogate Endpoint (SUR): Blood pressure
Study 21383650 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 21383650 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21383650 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17010798 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 14685865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9043728 — Surrogate Endpoint (SUR): Blood pressure
Study 18325725 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18325725 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18325725 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18325725 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31221870 — Surrogate Endpoint (SUR): Blood pressure
Study 31221870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26130070 — Surrogate Endpoint (SUR): Bone mineral density
Study 17023730 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 17023730 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 17023730 — Safety Biomarker (SAF): Reactive oxygen species
Study 15492298 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15492298 — Surrogate Endpoint (SUR): Blood pressure
Study 15492298 — Surrogate Endpoint (SUR): Serum creatinine
Study 15492298 — Surrogate Endpoint (SUR): Serum potassium
Study 30617139 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22113345 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 12410192 — Surrogate Endpoint (SUR): Bone mineral density
Study 12410192 — Surrogate Endpoint (SUR): Serum calcium
Study 1308699 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1308699 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31780038 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31780038 — Surrogate Endpoint (SUR): Blood pressure
Study 31780038 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31780038 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29493868 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 15569820 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1832906 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 24555753 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 8627066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8627066 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26463708 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 24708204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20426797 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 10470743 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 2350476 — Surrogate Endpoint (SUR): Blood pressure
Study 94176 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 31975479 — Surrogate Endpoint (SUR): Blood pressure
Study 25497262 — Surrogate Endpoint (SUR): Blood pressure
Study 9095076 — Surrogate Endpoint (SUR): Blood pressure
Study 27281813 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 29634749 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 27038614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23547084 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 12816726 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 1349301 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 3933893 — Surrogate Endpoint (SUR): Blood pressure
Study 22364818 — Surrogate Endpoint (SUR): Bone mineral density
Study 15179411 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27473326 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 25649025 — Surrogate Endpoint (SUR): Serum uric acid
Study 25649025 — Surrogate Endpoint (SUR): Serum creatinine
Study 25649025 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25649025 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25649025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17705052 — Predictive Biomarker (PRD): METTL5 mRNA
Genes: METTL5; DC3; HSPC133
Study 17705052 — Predictive Biomarker (PRD): TBK1 mRNA
Genes: TBK1; NAK
Study 15122753 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 9595363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23037619 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23037619 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 31484539 — Surrogate Endpoint (SUR): Bone mineral density
Study 11422030 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 11422030 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9716113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9716113 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 9716113 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18155704 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 16580907 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 12742558 — Surrogate Endpoint (SUR): Blood pressure
Study 12742558 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12742558 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8221821 — Surrogate Endpoint (SUR): Blood pressure
Study 3767522 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3767522 — Surrogate Endpoint (SUR): Blood pressure
Study 27561827 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 27561827 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20826250 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19383827 — Predictive Biomarker (PRD): SGK1 mRNA
Genes: SGK1; SGK
Study 19383827 — Predictive Biomarker (PRD): DUSP1 mRNA
Genes: DUSP1; CL100; MKP1; PTPN10; VH1
Study 12780397 — Surrogate Endpoint (SUR): Blood pressure
Study 12780397 — Surrogate Endpoint (SUR): Serum creatinine
Study 16102557 — Surrogate Endpoint (SUR): Bone mineral density
Study 7512356 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25699397 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17591530 — Surrogate Endpoint (SUR): Blood pressure
Study 16046102 — Surrogate Endpoint (SUR): Blood pressure
Study 30943313 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26871794 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25135040 — Surrogate Endpoint (SUR): Blood pressure
Study 17198906 — Surrogate Endpoint (SUR): Blood pressure
Study 11565518 — Surrogate Endpoint (SUR): Serum creatinine
Study 11565518 — Surrogate Endpoint (SUR): Blood pressure
Study 2732067 — Surrogate Endpoint (SUR): Blood pressure
Study 23490168 — Safety Biomarker (SAF): Reactive oxygen species
Study 21464685 — Surrogate Endpoint (SUR): Blood pressure
Study 18317875 — Surrogate Endpoint (SUR): Serum creatinine
Study 18317875 — Surrogate Endpoint (SUR): Blood pressure
Study 15519938 — Surrogate Endpoint (SUR): Blood pressure
Study 9284856 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9284856 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9284856 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9284856 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9284856 — Surrogate Endpoint (SUR): Blood pressure
Study 11388814 — Surrogate Endpoint (SUR): Blood pressure
Study 9094765 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2880689 — Surrogate Endpoint (SUR): Blood pressure
Study 30889454 — Surrogate Endpoint (SUR): Blood pressure
Study 17175489 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 17876019 — Surrogate Endpoint (SUR): Blood pressure
Study 11831621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2149913 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2149913 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 2149913 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29065142 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29065142 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17919378 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 22429362 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8678366 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27993166 — Surrogate Endpoint (SUR): Blood pressure
Study 7614530 — Surrogate Endpoint (SUR): Blood pressure
Study 3759744 — Surrogate Endpoint (SUR): Blood pressure
Study 27926473 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 18234565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18234565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18234565 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 18234565 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18234565 — Safety Biomarker (SAF): IL-6 and IL-10
Study 6407502 — Surrogate Endpoint (SUR): Blood pressure
Study 15274037 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 30875961 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 30875961 — Predictive Biomarker (PRD): PRPH2 mRNA
Genes: PRPH2; PRPH; RDS; TSPAN22
Study 7651456 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 22219100 — Surrogate Endpoint (SUR): Blood pressure
Study 19805643 — Surrogate Endpoint (SUR): Blood pressure
Study 16943683 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16943683 — Safety Biomarker (SAF): 51Cr-EDTA
Study 25948863 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 25948863 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25948863 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25948863 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 25948863 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 21961780 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 16611342 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29105987 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25118263 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9250553 — Predictive Biomarker (PRD): MPG mRNA
Genes: MPG; AAG; ANPG; MID1
Study 30319663 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30319663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30319663 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 30319663 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23148885 — Surrogate Endpoint (SUR): Blood pressure
Study 11072156 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11072156 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 11072156 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11072156 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 11072156 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11072156 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8821843 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18251212 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18251212 — Surrogate Endpoint (SUR): Blood pressure
Study 16825335 — Surrogate Endpoint (SUR): Serum creatinine
Study 10678254 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10678254 — Surrogate Endpoint (SUR): Blood pressure
Study 9010691 — Surrogate Endpoint (SUR): Blood pressure
Study 6377891 — Surrogate Endpoint (SUR): Blood pressure
Study 26611571 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26611571 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16472588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9604449 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 2422467 — Surrogate Endpoint (SUR): Blood pressure
Study 31575503 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 30521366 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 25941160 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23465039 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7889665 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 23980523 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23320821 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 23320821 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17714576 — Surrogate Endpoint (SUR): Blood pressure
Study 16160710 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12838495 — Surrogate Endpoint (SUR): Serum creatinine
Study 21623778 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 11514376 — Surrogate Endpoint (SUR): Blood pressure
Study 18297434 — Surrogate Endpoint (SUR): Blood pressure
Study 14576756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10526245 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 6341015 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23529273 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 23529273 — Surrogate Endpoint (SUR): Serum calcium
Study 16287602 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2695549 — Surrogate Endpoint (SUR): Blood pressure
Study 12767415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11323338 — Surrogate Endpoint (SUR): Blood pressure
Study 10376122 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 19148479 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15614997 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31393548 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22721642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22721642 — Surrogate Endpoint (SUR): Blood pressure
Study 17136007 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17136007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10751266 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9223837 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9223837 — Predictive Biomarker (PRD): VASH1 mRNA
Genes: VASH1; KIAA1036; VASH
Study 30526573 — Surrogate Endpoint (SUR): Blood pressure
Study 19477145 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 16912120 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16912120 — Surrogate Endpoint (SUR): Serum testosterone
Study 11144049 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29059273 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 20859637 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 20859637 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16996868 — Surrogate Endpoint (SUR): Blood pressure
Study 19890266 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 7563935 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23042313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18565887 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18565887 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 10051263 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10051263 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7674104 — Surrogate Endpoint (SUR): Blood pressure
Study 20797477 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9295485 — Surrogate Endpoint (SUR): Blood pressure
Study 11584093 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 2540005 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30004111 — Predictive Biomarker (PRD): DEFA5 mRNA
Genes: DEFA5; DEF5
Study 30004111 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 12369794 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 12369794 — Surrogate Endpoint (SUR): Bone mineral density
Study 19451915 — Predictive Biomarker (PRD): GRM3 mRNA
Genes: GRM3; GPRC1C; MGLUR3
Study 19451915 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 3115843 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18166408 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 30415553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30415553 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23132511 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17328999 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 15809948 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 11498318 — Surrogate Endpoint (SUR): Blood pressure
Study 8989009 — Surrogate Endpoint (SUR): Blood pressure
Study 25311651 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21306828 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 28977167 — Surrogate Endpoint (SUR): Blood pressure
Study 26607778 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25316464 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25415805 — Surrogate Endpoint (SUR): Serum potassium
Study 12821755 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 1379106 — Surrogate Endpoint (SUR): Blood pressure
Study 26729211 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 18426821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18426821 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18426821 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18426821 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18426821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16635750 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 16635750 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 16635750 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 3915460 — Surrogate Endpoint (SUR): Blood pressure
Study 23141790 — Surrogate Endpoint (SUR): Blood pressure
Study 9720517 — Surrogate Endpoint (SUR): Serum potassium
Study 29474863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25922848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18619686 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17362251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 12577374 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 12577374 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12577374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9502344 — Surrogate Endpoint (SUR): Blood pressure
Study 8017642 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 15330272 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21726496 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 19417675 — Surrogate Endpoint (SUR): Blood pressure