TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9064391 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22513778 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29527973 — Surrogate Endpoint (SUR): Blood pressure
Study 1695304 — Surrogate Endpoint (SUR): Blood pressure
Study 28716815 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25736164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21272712 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 10228117 — Predictive Biomarker (PRD): A2M mRNA
Genes: A2M; CPAMD5; FWP007
Study 24798350 — Safety Biomarker (SAF): Interleukin 1
Study 24798350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24798350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12452391 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7798068 — Surrogate Endpoint (SUR): Blood pressure
Study 7798068 — Surrogate Endpoint (SUR): Serum potassium
Study 9219164 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9219164 — Surrogate Endpoint (SUR): Serum creatinine
Study 18523440 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 742817 — Surrogate Endpoint (SUR): Blood pressure
Study 11522101 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15746633 — Surrogate Endpoint (SUR): Serum creatinine
Study 12153407 — Predictive Biomarker (PRD): TAL1 mRNA
Genes: TAL1; BHLHA17; SCL; TCL5
Study 7649709 — Surrogate Endpoint (SUR): Blood pressure
Study 7041937 — Surrogate Endpoint (SUR): Blood pressure
Study 7041937 — Surrogate Endpoint (SUR): Serum potassium
Study 28197774 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 3371084 — Surrogate Endpoint (SUR): Serum potassium
Study 24331628 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 20147334 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 30969142 — Surrogate Endpoint (SUR): Blood pressure
Study 9468366 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2202010 — Surrogate Endpoint (SUR): Serum creatinine
Study 28041700 — Surrogate Endpoint (SUR): Blood pressure
Study 30229691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30229691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30229691 — Surrogate Endpoint (SUR): Blood pressure
Study 22971205 — Surrogate Endpoint (SUR): Blood pressure
Study 22971205 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22971205 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22971205 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15125352 — Surrogate Endpoint (SUR): Blood pressure
Study 21995867 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 20923992 — Surrogate Endpoint (SUR): Blood pressure
Study 16447669 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 16447669 — Predictive Biomarker (PRD): WBP2NL mRNA
Genes: WBP2NL; PAWP
Study 16447669 — Surrogate Endpoint (SUR): Blood pressure
Study 12476043 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8248611 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 8248611 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22575076 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22575076 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 12679475 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11129745 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8919832 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 8919832 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25595151 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18795893 — Surrogate Endpoint (SUR): Blood pressure
Study 31397870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31397870 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19238088 — Surrogate Endpoint (SUR): Blood pressure
Study 16107993 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12553483 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9794736 — Surrogate Endpoint (SUR): Blood pressure
Study 25921522 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 25921522 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19786657 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 9142026 — Surrogate Endpoint (SUR): Blood pressure
Study 23252525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20517827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12132061 — Surrogate Endpoint (SUR): Blood pressure
Study 1828134 — Surrogate Endpoint (SUR): Serum creatinine
Study 29309387 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 23050401 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20031844 — Surrogate Endpoint (SUR): Blood pressure
Study 16607045 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19543129 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12110028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12110028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7818840 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30980399 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 28193219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28193219 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28193219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28193219 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28193219 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2694482 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 21441550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21441550 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21441550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19587779 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 19587779 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 19587779 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8064736 — Predictive Biomarker (PRD): PLAGL1 mRNA
Genes: PLAGL1; LOT1; ZAC
Study 19609280 — Predictive Biomarker (PRD): WNK1 mRNA
Genes: WNK1; HSN2; KDP; KIAA0344; PRKWNK1
Study 19609280 — Surrogate Endpoint (SUR): Blood pressure
Study 3370654 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17922971 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2632724 — Surrogate Endpoint (SUR): Blood pressure
Study 31900172 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 20978195 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 20978195 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20978195 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 20978195 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-34a
Genes: MIR34A
Study 20978195 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 20978195 — Safety Biomarker (SAF): let-7a
Study 20978195 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11143912 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 30212981 — Surrogate Endpoint (SUR): Blood pressure
Study 22088556 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 16290975 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7720340 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1759830 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 30669469 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30669469 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 30669469 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 17878209 — Surrogate Endpoint (SUR): Serum creatinine
Study 9087577 — Surrogate Endpoint (SUR): Blood pressure
Study 27624168 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9228196 — Surrogate Endpoint (SUR): Blood pressure
Study 22803101 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 16307694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16307694 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 16307694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28528472 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 28528472 — Surrogate Endpoint (SUR): Serum calcium
Study 26425050 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26425050 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23504925 — Surrogate Endpoint (SUR): Blood pressure
Study 11443512 — Surrogate Endpoint (SUR): Blood pressure
Study 25711327 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21406472 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19106583 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 10848778 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8646485 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24075485 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24075485 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17223855 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 17223855 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 6832198 — Surrogate Endpoint (SUR): Blood pressure
Study 31766467 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 29750027 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26324738 — Predictive Biomarker (PRD): Hormone receptor
Study 26324738 — Predictive Biomarker (PRD): INSR mRNA
Genes: INSR
Study 3333530 — Surrogate Endpoint (SUR): Blood pressure
Study 22014603 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17498072 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10923432 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 28927673 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22045924 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22045924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23378417 — Surrogate Endpoint (SUR): Serum calcium
Study 9707184 — Surrogate Endpoint (SUR): Blood pressure
Study 1515758 — Surrogate Endpoint (SUR): Blood pressure
Study 1515758 — Surrogate Endpoint (SUR): Serum creatinine
Study 27619190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30474376 — Surrogate Endpoint (SUR): Blood pressure
Study 28546097 — Surrogate Endpoint (SUR): Bone mineral density
Study 26725450 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18251758 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16855626 — Surrogate Endpoint (SUR): Blood pressure
Study 12826782 — Surrogate Endpoint (SUR): Blood pressure
Study 10389204 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 15037273 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 12970631 — Surrogate Endpoint (SUR): Blood pressure
Study 28717855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28717855 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21340661 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 1626496 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1626496 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12374540 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29059426 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29059426 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 29059426 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 29059426 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26670076 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 22381711 — Surrogate Endpoint (SUR): Blood pressure
Study 7625363 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21859748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21859748 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 21859748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21859748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21859748 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21859748 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21364149 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8479488 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30567595 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 30567595 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 27688786 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 27688786 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 27688786 — Predictive Biomarker (PRD): GLCCI1 mRNA
Genes: GLCCI1
Study 2015169 — Surrogate Endpoint (SUR): Blood pressure
Study 7129331 — Surrogate Endpoint (SUR): Blood pressure
Study 17296341 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17296341 — Surrogate Endpoint (SUR): Blood pressure
Study 17296341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10216370 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25473078 — Surrogate Endpoint (SUR): Serum calcium
Study 21175344 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19696363 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 19696363 — Predictive Biomarker (PRD): MYF6 mRNA
Genes: MYF6; BHLHC4; MRF4
Study 9670410 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7924541 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2507061 — Surrogate Endpoint (SUR): Blood pressure
Study 2507061 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 780037 — Surrogate Endpoint (SUR): Blood pressure
Study 31278705 — Safety Biomarker (SAF): Hyaluronic acid
Study 18693591 — Surrogate Endpoint (SUR): Serum calcium
Study 18693591 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 15328177 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15328177 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2479252 — Surrogate Endpoint (SUR): Serum potassium
Study 28796130 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26722513 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26722513 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 23752288 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 15930482 — Safety Biomarker (SAF): Reactive oxygen species
Study 10513801 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19484170 — Surrogate Endpoint (SUR): Bone mineral density
Study 1395117 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27569734 — Surrogate Endpoint (SUR): Blood pressure
Study 15800921 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 15800921 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 8954302 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 1772813 — Surrogate Endpoint (SUR): Blood pressure
Study 21351399 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 21351399 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 10576139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10576139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1986565 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 1986565 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 25065668 — Predictive Biomarker (PRD): Hormone receptor
Study 11338314 — Surrogate Endpoint (SUR): Blood pressure
Study 22585886 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22585886 — Surrogate Endpoint (SUR): Blood pressure
Study 22297687 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 22297687 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 12442921 — Surrogate Endpoint (SUR): Serum creatinine
Study 26669417 — Surrogate Endpoint (SUR): Blood pressure
Study 24906585 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24906585 — Safety Biomarker (SAF): BDNF
Study 16038456 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16038456 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16510610 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9298513 — Safety Biomarker (SAF): DRD2
Study 7914737 — Surrogate Endpoint (SUR): Blood pressure
Study 23246022 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23246022 — Predictive Biomarker (PRD): Hormone receptor
Study 20622656 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 20622656 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 20622656 — Predictive Biomarker (PRD): Metallothionein-1A
Genes: MT1A; MT1S
Study 20622656 — Predictive Biomarker (PRD): MT1A mRNA
Genes: MT1A; MT1S
Study 18783301 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18783301 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18783301 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18783301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16635593 — Surrogate Endpoint (SUR): Blood pressure
Study 16635593 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16635593 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14616319 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8521205 — Surrogate Endpoint (SUR): Blood pressure
Study 19909427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10701730 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9347592 — Surrogate Endpoint (SUR): Blood pressure
Study 2190251 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 31683483 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 21725881 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16790652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25044383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10471824 — Predictive Biomarker (PRD): PRTN3 mRNA
Genes: PRTN3; MBN
Study 14716800 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23625113 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23625113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23625113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23625113 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23625113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9387348 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 2857212 — Surrogate Endpoint (SUR): Serum creatinine
Study 2857212 — Surrogate Endpoint (SUR): Serum uric acid
Study 20153039 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17512638 — Surrogate Endpoint (SUR): Serum creatinine
Study 2649120 — Surrogate Endpoint (SUR): Blood pressure
Study 26815593 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26815593 — Safety Biomarker (SAF): BDNF
Study 21474517 — Surrogate Endpoint (SUR): Blood pressure
Study 31439579 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31439579 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 31439579 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL