TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15975490 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15975490 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7893502 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 27167219 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 20156473 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 16206003 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16206003 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 8649684 — Surrogate Endpoint (SUR): Serum sodium
Study 17885017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26556603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19395466 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study 24711637 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 23873545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19703383 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 11701711 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 30293166 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 30293166 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 12198057 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9865671 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9865671 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3219226 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18525029 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 11192305 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 11192305 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11192305 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25611962 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 18024211 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 18024211 — Surrogate Endpoint (SUR): Pathological complete response
Study 10852758 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8261405 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24732316 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 18188581 — Surrogate Endpoint (SUR): Serum creatinine
Study 18188581 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 12719441 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12719441 — Surrogate Endpoint (SUR): Blood pressure
Study 10818412 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1611221 — Surrogate Endpoint (SUR): Bone mineral density
Study 27555316 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16294137 — Surrogate Endpoint (SUR): Bone mineral density
Study 31318038 — Surrogate Endpoint (SUR): Blood pressure
Study 19369404 — Surrogate Endpoint (SUR): Serum creatinine
Study 16673804 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 3526151 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20970202 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19055278 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 7583550 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25399620 — Safety Biomarker (SAF): Hyaluronic acid
Study 20299958 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12397049 — Surrogate Endpoint (SUR): Blood pressure
Study 12397049 — Surrogate Endpoint (SUR): Serum creatinine
Study 18560642 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 8960901 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30822290 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20031608 — Predictive Biomarker (PRD): CACNA1C mRNA
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 9724825 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3729450 — Predictive Biomarker (PRD): SMARCA2 mRNA
Genes: SMARCA2; BAF190B; BRM; SNF2A; SNF2L2
Study 30406696 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 30406696 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 30406696 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 24278177 — Predictive Biomarker (PRD): C4A mRNA
Genes: C4A; CO4; CPAMD2
Study 24278177 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 24278177 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17080541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17080541 — Surrogate Endpoint (SUR): Bone mineral density
Study 3304301 — Surrogate Endpoint (SUR): Blood pressure
Study 29128895 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29128895 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8768868 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 6189601 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 3106459 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31665956 — Surrogate Endpoint (SUR): Serum sodium
Study 18471347 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 14693322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29648856 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 20622529 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16326171 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 16326171 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 11386203 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 4008112 — Surrogate Endpoint (SUR): Blood pressure
Study 26070528 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26070528 — Surrogate Endpoint (SUR): Blood pressure
Study 1584314 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 1764944 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 1764944 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 1764944 — Predictive Biomarker (PRD): BRCA2
Genes: FAD; FAD1; BRCC2; XRCC11
Study 1764944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17287680 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30082870 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 30082870 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 24462043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24462043 — Surrogate Endpoint (SUR): Blood pressure
Study 20470283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30219394 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 21842214 — Predictive Biomarker (PRD): ACTN3 mRNA
Genes: ACTN3
Study 28403127 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 28403127 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 28403127 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 28663304 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 15292626 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3323852 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16855773 — Surrogate Endpoint (SUR): Serum testosterone
Study 16163531 — Surrogate Endpoint (SUR): Blood pressure
Study 11921421 — Surrogate Endpoint (SUR): Blood pressure
Study 7594412 — Surrogate Endpoint (SUR): Blood pressure
Study 31654643 — Surrogate Endpoint (SUR): Blood pressure
Study 28577292 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28577292 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7923916 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2839538 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21045734 — Surrogate Endpoint (SUR): Blood pressure
Study 1290920 — Surrogate Endpoint (SUR): Blood pressure
Study 1290920 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1290920 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26825826 — Predictive Biomarker (PRD): RRH mRNA
Genes: RRH
Study 17420419 — Surrogate Endpoint (SUR): Blood pressure
Study 31586879 — Surrogate Endpoint (SUR): Blood pressure
Study 31586879 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31586879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20694407 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12053591 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 20664284 — Surrogate Endpoint (SUR): Blood pressure
Study 20664284 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11475748 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7806419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7806419 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 7806419 — Safety Biomarker (SAF): Interleukin 1
Study 7806419 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2561379 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8924192 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 22835900 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22835900 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28445193 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 28445193 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 23895820 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16779534 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16779534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16779534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16779534 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 8466022 — Surrogate Endpoint (SUR): Blood pressure
Study 28340145 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 20237760 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20237760 — Surrogate Endpoint (SUR): Blood pressure
Study 3046626 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 3046626 — Surrogate Endpoint (SUR): Blood pressure
Study 25804100 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25804100 — Surrogate Endpoint (SUR): Blood pressure
Study 16220085 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12239424 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 22131290 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25757757 — Surrogate Endpoint (SUR): Blood pressure
Study 23602498 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23602498 — Safety Biomarker (SAF): BDNF
Study 10815854 — Predictive Biomarker (PRD): Hormone receptor
Study 8986924 — Surrogate Endpoint (SUR): Blood pressure
Study 24161018 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24161018 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2643088 — Surrogate Endpoint (SUR): Blood pressure
Study 28222674 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 28222674 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 23031470 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 1827011 — Surrogate Endpoint (SUR): Blood pressure
Study 24558079 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19183164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7852746 — Surrogate Endpoint (SUR): Blood pressure
Study 25374187 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 17981439 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17981439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2003706 — Surrogate Endpoint (SUR): Blood pressure
Study 26685718 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26685718 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20371128 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12734059 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10410585 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8533869 — Surrogate Endpoint (SUR): Blood pressure
Study 8533869 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 31599043 — Surrogate Endpoint (SUR): Serum potassium
Study 31651118 — Surrogate Endpoint (SUR): Pathological complete response
Study 26147760 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 26147760 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 24295397 — Surrogate Endpoint (SUR): Blood pressure
Study 31757473 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 30928020 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 30928020 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 27384245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19170908 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19170908 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11943448 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11943448 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25351352 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25351352 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 22564997 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 8948386 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8948386 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6381884 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 6381884 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 6381884 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29972709 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11953546 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 803977 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 22537562 — Surrogate Endpoint (SUR): Blood pressure
Study 15823628 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12092978 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 12092978 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 22648841 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10319572 — Surrogate Endpoint (SUR): Blood pressure
Study 28062296 — Safety Biomarker (SAF): miR-30c
Study 22815003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17156345 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10612317 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10612317 — Surrogate Endpoint (SUR): Serum creatinine
Study 15477125 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15477125 — Surrogate Endpoint (SUR): Blood pressure
Study 15477125 — Surrogate Endpoint (SUR): Serum potassium
Study 11684081 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22134732 — Surrogate Endpoint (SUR): Bone mineral density
Study 10989990 — Surrogate Endpoint (SUR): Blood pressure
Study 8347328 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29940151 — Surrogate Endpoint (SUR): Blood pressure
Study 4042543 — Surrogate Endpoint (SUR): Blood pressure
Study 31206016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31206016 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29237386 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22354457 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22354457 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 20849620 — Surrogate Endpoint (SUR): Blood pressure
Study 17761704 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25033789 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 22441301 — Surrogate Endpoint (SUR): Blood pressure
Study 12165574 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 10064126 — Predictive Biomarker (PRD): HOPX mRNA
Genes: HOPX; HOD; HOP; LAGY; NECC1; OB1
Study 16038680 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 8901800 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30630804 — Surrogate Endpoint (SUR): Blood pressure
Study 26526816 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26526816 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22426327 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18722511 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18722511 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18722511 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16104989 — Surrogate Endpoint (SUR): Serum creatinine
Study 26139093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26139093 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26139093 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25311600 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 25311600 — Predictive Biomarker (PRD): PTPRU mRNA
Genes: PTPRU; FMI; PCP2; PTPRO
Study 23986168 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 22614148 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10025425 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 1323545 — Surrogate Endpoint (SUR): Blood pressure
Study 31952456 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 8237937 — Monitoring Biomarker (MOI): HBV DNA
Study 28074489 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 19403504 — Surrogate Endpoint (SUR): Blood pressure
Study 30569637 — Surrogate Endpoint (SUR): Blood pressure
Study 16428745 — Predictive Biomarker (PRD): TERF1 mRNA
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study 16428745 — Predictive Biomarker (PRD): CLSTN1 mRNA
Genes: CLSTN1; CS1; KIAA0911
Study 16428745 — Predictive Biomarker (PRD): CLSTN3 mRNA
Genes: CLSTN3; CS3; KIAA0726
Study 15325933 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3323262 — Surrogate Endpoint (SUR): Blood pressure
Study 30415890 — Surrogate Endpoint (SUR): Blood pressure
Study 27400949 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 22748821 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20499017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11022057 — Surrogate Endpoint (SUR): Blood pressure
Study 19958132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19958132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10408585 — Surrogate Endpoint (SUR): Blood pressure
Study 29401297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27762512 — Surrogate Endpoint (SUR): Serum creatinine
Study 21294404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21294404 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17506592 — Surrogate Endpoint (SUR): Bone mineral density
Study 12093429 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 12093429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7477146 — Surrogate Endpoint (SUR): Blood pressure
Study 2011406 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 2011406 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2011406 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21824444 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 21824444 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 12111110 — Surrogate Endpoint (SUR): Serum creatinine
Study 7560251 — Surrogate Endpoint (SUR): Blood pressure
Study 436308 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 31274484 — Surrogate Endpoint (SUR): Blood pressure
Study 26595300 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 23249429 — Surrogate Endpoint (SUR): Blood pressure
Study 23249429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23455721 — Surrogate Endpoint (SUR): Blood pressure
Study 21282560 — Surrogate Endpoint (SUR): Blood pressure
Study 20306755 — Surrogate Endpoint (SUR): Blood pressure
Study 7818648 — Surrogate Endpoint (SUR): Blood pressure
Study 7818648 — Surrogate Endpoint (SUR): Serum potassium