TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03132584 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT03132584 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT03132584 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT01412957 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04181827 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT00212147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01291667 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04364984 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01870739 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03760965 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01786070 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04389619 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study NCT03691194 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02425098 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03345290 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04888663 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00054587 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03284281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03284281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01488071 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study NCT02498119 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study NCT02498119 — Predictive Biomarker (PRD): MAPK1 mRNA
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study NCT04405960 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT01041248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00002845 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03615040 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT03615040 — Predictive Biomarker (PRD): IL33 mRNA
Genes: IL33; C9orf26; IL1F11; NFHEV
Study NCT01284114 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00598975 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT04271098 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT04271098 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04271098 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT00374829 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03150498 — Predictive Biomarker (PRD): BTD mRNA
Genes: BTD
Study NCT02269085 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04760743 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT06445452 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study NCT01837693 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00310830 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00310830 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01188005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04088734 — Predictive Biomarker (PRD): SGSH mRNA
Genes: SGSH; HSS
Study NCT03020862 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05576571 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT00741156 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04232332 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02452372 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study NCT01010230 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00896701 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01900171 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04009941 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00220246 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04304131 — Predictive Biomarker (PRD): SDC2 mRNA
Genes: SDC2; HSPG1
Study NCT00980018 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00980018 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00188630 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02372227 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01362478 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01362478 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT01362478 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT02262208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03496207 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03496207 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02389556 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study NCT02389556 — Predictive Biomarker (PRD): ANGPTL8 mRNA
Genes: ANGPTL8; C19orf80; RIFL; UNQ599/PRO1185
Study NCT04688294 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04688294 — Surrogate Endpoint (SUR): Serum sodium
Study NCT04184817 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT02505282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02373111 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02373111 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study NCT02373111 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study NCT03426020 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03941704 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03941704 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03941704 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01482910 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03730142 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02595541 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02595541 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02595541 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00943306 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT04317651 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04282031 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04282031 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04282031 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT04309084 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03983395 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00482118 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02494622 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study NCT00053027 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study NCT02274337 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02274337 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03859570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02669628 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02661009 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03439033 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02005120 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02005120 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05116124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02981433 — Predictive Biomarker (PRD): S1PR1 mRNA
Genes: S1PR1; CHEDG1; EDG1
Study NCT02975687 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02226926 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study NCT01978379 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01978379 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00784667 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00784667 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02348359 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04790409 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00982852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00824980 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00824980 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study NCT01486030 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study NCT00899093 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study NCT04624425 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03078127 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT03078127 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT04409938 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03287128 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT04360967 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02090751 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04520438 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00853502 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00263185 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03562065 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00117156 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study NCT00117156 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03371641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study NCT04032509 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT01428466 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03056105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03056105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02996617 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04182984 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study NCT02560025 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT00439816 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01687725 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01886989 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03854994 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03054038 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03664128 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT03664128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02846103 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02846103 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT02846103 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02473146 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT01435655 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT03050411 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03050411 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT03050411 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00376467 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00376467 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01363739 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02463253 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04237142 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study NCT03018574 — Predictive Biomarker (PRD): NDRG2 mRNA
Genes: NDRG2; KIAA1248; SYLD
Study NCT01124864 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01124864 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01124864 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study NCT01124864 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01124864 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04093596 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03480087 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT02803346 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05124223 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00180128 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01915576 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study NCT01052649 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03734757 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00294541 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02514967 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT01132001 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01601899 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT03869684 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03869684 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04208295 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00425516 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01120665 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01814059 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04360356 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02098954 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00943072 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00943072 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00855660 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study NCT02933450 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02258607 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00968435 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00005483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01788358 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04167345 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT01461044 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01461044 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04523974 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02988102 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT02070861 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02620527 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01421472 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01335737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04498299 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02137408 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01069445 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT02009878 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01392170 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04269395 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT01712152 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01200784 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT01200784 — Surrogate Endpoint (SUR): Serum phosphate
Study NCT02809222 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03838458 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03838458 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT03838458 — Predictive Biomarker (PRD): HOXA13 mRNA
Genes: HOXA13; HOX1J
Study NCT03838458 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00433329 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02296242 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study NCT04738760 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT01224951 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study NCT00145652 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study NCT00217659 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00001378 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT00775814 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04474288 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01807416 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04095169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01497977 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02135003 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04798443 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02554591 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03080116 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT02990624 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02021409 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00131053 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00131053 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03838471 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT02872506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03260582 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00518479 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03478774 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02067585 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00447785 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT00447785 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT00019383 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00897429 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study NCT00897429 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00897429 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT00897429 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study NCT01109940 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT03635450 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04844255 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study NCT04844255 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03342950 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study NCT00496405 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03568877 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT01809093 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study NCT01809093 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study NCT04606537 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04182854 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01564836 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT01169844 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT02658071 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study NCT01245569 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01497054 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03123406 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT01411735 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00395642 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04524611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2