TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19346430 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2803986 — Surrogate Endpoint (SUR): Blood pressure
Study 27956003 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27956003 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27956003 — Surrogate Endpoint (SUR): Blood pressure
Study 24392946 — Surrogate Endpoint (SUR): Bone mineral density
Study 28524699 — Surrogate Endpoint (SUR): Blood pressure
Study 11703344 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 3107487 — Surrogate Endpoint (SUR): Serum calcium
Study 22047466 — Predictive Biomarker (PRD): CPQ mRNA
Genes: CPQ; LCH1; PGCP
Study 18930568 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18930568 — Surrogate Endpoint (SUR): Serum creatinine
Study 8669235 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 31731214 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 28632555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28632555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7738617 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26253455 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15735546 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12846058 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 12846058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24947878 — Surrogate Endpoint (SUR): Blood pressure
Study 28412986 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 24112419 — Surrogate Endpoint (SUR): Blood pressure
Study 24112419 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 9285295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24347577 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 22151469 — Predictive Biomarker (PRD): ABCD2 mRNA
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study 11702663 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 31609072 — Safety Biomarker (SAF): Reactive oxygen species
Study 23595135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10950445 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10950445 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 7938102 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7938102 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 25153307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25637323 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25637323 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17681303 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 16256442 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 14617263 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25417402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25417402 — Safety Biomarker (SAF): IL-6 and IL-10
Study 1603140 — Surrogate Endpoint (SUR): Bone mineral density
Study 29664000 — Surrogate Endpoint (SUR): Blood pressure
Study 28769121 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 24715380 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 24715380 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 24715380 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17582159 — Surrogate Endpoint (SUR): Serum creatinine
Study 9652303 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9652303 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2498781 — Surrogate Endpoint (SUR): Serum creatinine
Study 2498781 — Surrogate Endpoint (SUR): Serum potassium
Study 27281879 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 10162149 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 1873013 — Surrogate Endpoint (SUR): Blood pressure
Study 2191588 — Surrogate Endpoint (SUR): Blood pressure
Study 31258082 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29766004 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 25281045 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 8270757 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8270757 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8270757 — Surrogate Endpoint (SUR): Serum triglycerides
Study 808195 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16825681 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 12513955 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 30606137 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26467819 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 17317370 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15076156 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15076156 — Surrogate Endpoint (SUR): Blood pressure
Study 9316621 — Safety Biomarker (SAF): Interleukin 1
Study 31699671 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 31699671 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 23200974 — Surrogate Endpoint (SUR): Blood pressure
Study 28438257 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 16168728 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 6818596 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 26803719 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22811499 — Surrogate Endpoint (SUR): Blood pressure
Study 22811499 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20643092 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12748463 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 27223302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27223302 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22424011 — Surrogate Endpoint (SUR): Serum creatinine
Study 22424011 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22424011 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16009955 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9030363 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11952670 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27002062 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20167142 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20975465 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 10725579 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 10725579 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30913204 — Safety Biomarker (SAF): Reactive oxygen species
Study 30913204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30913204 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22668800 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20923960 — Surrogate Endpoint (SUR): Blood pressure
Study 12428181 — Surrogate Endpoint (SUR): Blood pressure
Study 25074396 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 10788023 — Surrogate Endpoint (SUR): Blood pressure
Study 2199290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12131187 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21041278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21041278 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21041278 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15145877 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 30690511 — Surrogate Endpoint (SUR): Bone mineral density
Study 17984104 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17984104 — Surrogate Endpoint (SUR): Blood pressure
Study 15710957 — Monitoring Biomarker (MOI): HBV DNA
Study 12804927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6432869 — Surrogate Endpoint (SUR): Blood pressure
Study 18758125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18758125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15641102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15641102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25186034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23850450 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16123739 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 11313302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28346581 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 23341981 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18434890 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9372546 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11953922 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1834808 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1834808 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 6772047 — Surrogate Endpoint (SUR): Blood pressure
Study 28506538 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7921994 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30689800 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 26764156 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 18591401 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 18591401 — Surrogate Endpoint (SUR): Blood pressure
Study 8621857 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 20137596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16685553 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 10597779 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10597779 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 16372388 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 6225751 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19754679 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study 9808867 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 3181646 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23297321 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 19407804 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 19407804 — Surrogate Endpoint (SUR): Blood pressure
Study 11273059 — Surrogate Endpoint (SUR): Blood pressure
Study 18454988 — Surrogate Endpoint (SUR): Blood pressure
Study 28326559 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28326559 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28326559 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 26490026 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26490026 — Surrogate Endpoint (SUR): Pathological complete response
Study 21469913 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 12832710 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 12832710 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10683600 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9928576 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27959700 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19688181 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19688181 — Surrogate Endpoint (SUR): Serum creatinine
Study 3538156 — Surrogate Endpoint (SUR): Blood pressure
Study 22801381 — Surrogate Endpoint (SUR): Serum calcium
Study 12091753 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12091753 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12091753 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31220476 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 892352 — Surrogate Endpoint (SUR): Serum sodium
Study 892352 — Surrogate Endpoint (SUR): Serum potassium
Study 29401355 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 27401657 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 22124795 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 9655370 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9655370 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 5002114 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18926641 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 18926641 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11396366 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 8234907 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31915255 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 21098871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21098871 — Surrogate Endpoint (SUR): Blood pressure
Study 21098871 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14725659 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 14725659 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14725659 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9478066 — Surrogate Endpoint (SUR): Serum creatinine
Study 28103746 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 24621680 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20642691 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11448655 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11448655 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24521630 — Surrogate Endpoint (SUR): Bone mineral density
Study 9951580 — Surrogate Endpoint (SUR): Blood pressure
Study 12813203 — Safety Biomarker (SAF): 51Cr-EDTA
Study 7528560 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7528560 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2921600 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 23691062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19293593 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8453559 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20198451 — Surrogate Endpoint (SUR): Serum creatinine
Study 10614835 — Safety Biomarker (SAF): Reactive oxygen species
Study 8549868 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8549868 — Surrogate Endpoint (SUR): Blood pressure
Study 1846057 — Surrogate Endpoint (SUR): Blood pressure
Study 30744672 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 26400476 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9793619 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9793619 — Surrogate Endpoint (SUR): Blood pressure
Study 25605838 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24923372 — Surrogate Endpoint (SUR): Blood pressure
Study 11603453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11603453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9847641 — Surrogate Endpoint (SUR): Blood pressure
Study 8079969 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 19761135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19761135 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17931382 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11700404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29614243 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 8990802 — Surrogate Endpoint (SUR): Blood pressure
Study 22782352 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 22782352 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 2089252 — Surrogate Endpoint (SUR): Bone mineral density
Study 9745422 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31231136 — Monitoring Biomarker (MOI): Cell-free DNA
Study 28508579 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 26375689 — Surrogate Endpoint (SUR): Blood pressure
Study 16442211 — Surrogate Endpoint (SUR): Blood pressure
Study 14709244 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9420308 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2872811 — Surrogate Endpoint (SUR): Blood pressure
Study 23965882 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1951337 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30777094 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 22436075 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 17987065 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 11053698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22914552 — Predictive Biomarker (PRD): APOA5 mRNA
Genes: APOA5; RAP3; UNQ411/PRO773
Study 17242321 — Surrogate Endpoint (SUR): Bone mineral density
Study 22998386 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17266173 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11174476 — Surrogate Endpoint (SUR): Bone mineral density
Study 791471 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 28592573 — Surrogate Endpoint (SUR): Blood pressure
Study 10794844 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 1961649 — Surrogate Endpoint (SUR): Blood pressure
Study 20709514 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 20709514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20814331 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12297475 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12297475 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 12297475 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 8789588 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8789588 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 29231586 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25248340 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23881337 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 21199997 — Surrogate Endpoint (SUR): Blood pressure
Study 19816812 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 19816812 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19816812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19816812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19816812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21546491 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11763992 — Surrogate Endpoint (SUR): Serum creatinine
Study 31621054 — Predictive Biomarker (PRD): DHODH mRNA
Genes: DHODH
Study 21925823 — Surrogate Endpoint (SUR): Blood pressure
Study 11910315 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11910315 — Surrogate Endpoint (SUR): Blood pressure
Study 29439405 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29439405 — Surrogate Endpoint (SUR): Bone mineral density
Study 20847709 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20847709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor