TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23939283 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23940128 — Predictive Biomarker (PRD): POU1F1 mRNA
Genes: POU1F1; GHF1; PIT1
Study 23940128 — Predictive Biomarker (PRD): LHX4 mRNA
Genes: LHX4
Study 23940128 — Predictive Biomarker (PRD): HESX1 mRNA
Genes: HESX1; HANF
Study 23940128 — Predictive Biomarker (PRD): OTX2 mRNA
Genes: OTX2
Study 23940128 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study 23940282 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 23940282 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 23940282 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 23940282 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 23940282 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 23940282 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 23940282 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 23940282 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 23940282 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 23942767 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23942767 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 23942767 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 23942908 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 23945372 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23947473 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 23950152 — Predictive Biomarker (PRD): IMPDH1 mRNA
Genes: IMPDH1; IMPD1
Study 23950152 — Predictive Biomarker (PRD): KLHL7 mRNA
Genes: KLHL7
Study 23950152 — Predictive Biomarker (PRD): NR2E3 mRNA
Genes: NR2E3; PNR; RNR
Study 23950152 — Predictive Biomarker (PRD): PRPF3 mRNA
Genes: PRPF3; HPRP3; PRP3
Study 23950152 — Predictive Biomarker (PRD): PRPF31 mRNA
Genes: PRPF31; PRP31
Study 23950152 — Predictive Biomarker (PRD): PRPH2 mRNA
Genes: PRPH2; PRPH; RDS; TSPAN22
Study 23950152 — Predictive Biomarker (PRD): RP2 mRNA
Genes: RP2
Study 23953269 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 23958949 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 23958949 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23958949 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 23965936 — Surrogate Endpoint (SUR): Blood pressure
Study 23966579 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23966579 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23966579 — Predictive Biomarker (PRD): TK1 mRNA
Genes: TK1
Study 23966579 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 23966867 — Predictive Biomarker (PRD): LHX2 mRNA
Genes: LHX2; LH2
Study 23966867 — Predictive Biomarker (PRD): RREB1 mRNA
Genes: RREB1; FINB
Study 23966867 — Predictive Biomarker (PRD): TBX15 mRNA
Genes: TBX15; TBX14
Study 23966867 — Predictive Biomarker (PRD): GRB14 mRNA
Genes: GRB14
Study 23966867 — Predictive Biomarker (PRD): ADAMTS9 mRNA
Genes: ADAMTS9; KIAA1312
Study 23966867 — Predictive Biomarker (PRD): LY86 mRNA
Genes: LY86; MD1
Study 23966867 — Predictive Biomarker (PRD): RSPO3 mRNA
Genes: RSPO3; PWTSR; THSD2
Study 23966867 — Predictive Biomarker (PRD): ITPR2 mRNA
Genes: ITPR2
Study 23968316 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 23971740 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 23971740 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23972788 — Predictive Biomarker (PRD): DUSP2 mRNA
Genes: DUSP2; PAC1
Study 23973693 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23973693 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23975330 — Surrogate Endpoint (SUR): Blood pressure
Study 23975665 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23975665 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23978271 — Surrogate Endpoint (SUR): Blood pressure
Study 23979273 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 23979288 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23979353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23979787 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 23979787 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 23980534 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23982888 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23983245 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23983680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 23983680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23983680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): RPRM mRNA
Genes: RPRM
Study 23983680 — Monitoring Biomarker (MOI): Cell-free DNA
Study 23983684 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23983684 — Surrogate Endpoint (SUR): Blood pressure
Study 23984050 — Surrogate Endpoint (SUR): Blood pressure
Study 23985703 — Surrogate Endpoint (SUR): Blood pressure
Study 23985807 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 23986161 — Surrogate Endpoint (SUR): Serum calcium
Study 23986513 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 23986513 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23987834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23988361 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 23990665 — Surrogate Endpoint (SUR): Serum calcium
Study 23991111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23991111 — Safety Biomarker (SAF): Interleukin 1
Study 23996499 — Surrogate Endpoint (SUR): Blood pressure
Study 23996808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23998235 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24001533 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24002394 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24002394 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 24002394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24002394 — Surrogate Endpoint (SUR): Serum creatinine
Study 24002496 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 24004934 — Surrogate Endpoint (SUR): Blood pressure
Study 24007627 — Safety Biomarker (SAF): miR-375
Genes: MIR375
Study 24007627 — Safety Biomarker (SAF): miR-200c
Genes: MIR200C
Study 24007627 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): miR-124
Study 24007746 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24007746 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 24008570 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24009220 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24009220 — Surrogate Endpoint (SUR): Serum creatinine
Study 24010976 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 24013510 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24014659 — Surrogate Endpoint (SUR): Blood pressure
Study 24016493 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 24019244 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24019397 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24023791 — Predictive Biomarker (PRD): HDGFL2 mRNA
Genes: HDGFL2; HDGF2; HDGFRP2; HRP2; UNQ785/PRO1604
Study 24024534 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24025234 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 24025631 — Surrogate Endpoint (SUR): Blood pressure
Study 24027187 — Predictive Biomarker (PRD): FUT2 mRNA
Genes: FUT2; SEC2
Study 24027187 — Predictive Biomarker (PRD): FUT3 mRNA
Genes: FUT3; FT3B; LE
Study 24028306 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 24028306 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24028306 — Surrogate Endpoint (SUR): Blood pressure
Study 24028677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 24028745 — Safety Biomarker (SAF): DRD2
Study 24029408 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24030379 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 24032456 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 24033923 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24033923 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 24035405 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 24041790 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 24041790 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 24047918 — Surrogate Endpoint (SUR): Bone mineral density
Study 24047921 — Surrogate Endpoint (SUR): Blood pressure
Study 24048673 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24049022 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24050953 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24051172 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24051172 — Predictive Biomarker (PRD): Hormone receptor
Study 24051744 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 24055823 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 24057647 — Predictive Biomarker (PRD): FIP1L1 mRNA
Genes: FIP1L1; FIP1; RHE
Study 24059479 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 24059479 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24059479 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24059787 — Surrogate Endpoint (SUR): Blood pressure
Study 24062394 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 24062895 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24063735 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24065152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24065152 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24075467 — Surrogate Endpoint (SUR): Blood pressure
Study 24075534 — Surrogate Endpoint (SUR): Hematologic response
Study 24075648 — Surrogate Endpoint (SUR): Blood pressure
Study 24076699 — Safety Biomarker (SAF): Hyaluronic acid
Study 24077845 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 24077845 — Predictive Biomarker (PRD): GATA2 mRNA
Genes: GATA2
Study 24077846 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24077846 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 24077916 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24079306 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24080250 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24080250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24081970 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 24081973 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 24082310 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 24082310 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 24082310 — Surrogate Endpoint (SUR): Bone mineral density
Study 24088306 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24088306 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 24088306 — Surrogate Endpoint (SUR): Blood pressure
Study 24088548 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 24089587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24090077 — Surrogate Endpoint (SUR): Blood pressure
Study 24091623 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24091623 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24091623 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 24092875 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24093428 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24093540 — Safety Biomarker (SAF): Interleukin 1
Study 24093540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24093770 — Surrogate Endpoint (SUR): Blood pressure
Study 24094497 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24095247 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 24099345 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24100924 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 24101373 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 24101663 — Surrogate Endpoint (SUR): Blood pressure
Study 24103704 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 24105925 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24106922 — Surrogate Endpoint (SUR): Blood pressure
Study 24108222 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 24114613 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 24114613 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24114613 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 24114613 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24119589 — Surrogate Endpoint (SUR): Blood pressure
Study 24120120 — Surrogate Endpoint (SUR): Bone mineral density
Study 24122508 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 24122716 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 24122913 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24124377 — Surrogate Endpoint (SUR): Blood pressure
Study 24127057 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 24128439 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 24128439 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 24128439 — Predictive Biomarker (PRD): CYP27A1 mRNA
Genes: CYP27A1; CYP27
Study 24128439 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 24128715 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 24128715 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24130889 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24132613 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24134221 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24135755 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24135755 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 24136113 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24136335 — Predictive Biomarker (PRD): ABCA3 mRNA
Genes: ABCA3; ABC3
Study 24140416 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study 24141969 — Surrogate Endpoint (SUR): Blood pressure
Study 24143213 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 24143213 — Predictive Biomarker (PRD): SLC19A1 mRNA
Genes: SLC19A1; FLOT1; RFC1
Study 24145345 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 24145457 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 24145879 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24146089 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 24146220 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24146220 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24152822 — Surrogate Endpoint (SUR): Blood pressure
Study 24152982 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 24152982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24152982 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 24153343 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 24155635 — Predictive Biomarker (PRD): Hormone receptor
Study 24155635 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24156629 — Surrogate Endpoint (SUR): Blood pressure
Study 24158411 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24158411 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24161160 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24161161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24162333 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24162333 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 24164965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24170105 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 24174627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24174627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24174627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24175592 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24177180 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24177377 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 24180494 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24180494 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 24182742 — Surrogate Endpoint (SUR): Blood pressure
Study 24184254 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 24184736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24184736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24189773 — Surrogate Endpoint (SUR): Blood pressure
Study 24190901 — Surrogate Endpoint (SUR): Blood pressure
Study 24192652 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 24198310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24200998 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 24201857 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24203067 — Predictive Biomarker (PRD): PPARGC1B mRNA
Genes: PPARGC1B; PERC; PGC1; PGC1B; PPARGC1
Study 24203067 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study 24203067 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 24203067 — Predictive Biomarker (PRD): ABCC9 mRNA
Genes: ABCC9; SUR2
Study 24203067 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 24203067 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 24204746 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24204746 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 24205333 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 24205333 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 24205333 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24210779 — Surrogate Endpoint (SUR): Blood pressure
Study 24211066 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24214373 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24218035 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24218035 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 24218035 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 24218191 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24218513 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 24222348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24222348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24227820 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 24234516 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24237764 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24237764 — Surrogate Endpoint (SUR): Blood pressure
Study 24239220 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 24240933 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24240933 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24240933 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24241210 — Predictive Biomarker (PRD): CCND1
Genes: U21B31