TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25450293 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 22263401 — Surrogate Endpoint (SUR): Blood pressure
Study 11967670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11967670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2244441 — Surrogate Endpoint (SUR): Blood pressure
Study 420388 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 12063455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12063455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12063455 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12063455 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8582466 — Surrogate Endpoint (SUR): Blood pressure
Study 8582466 — Surrogate Endpoint (SUR): Serum potassium
Study 16026361 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16026361 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29049180 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 22172646 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22172646 — Predictive Biomarker (PRD): Hormone receptor
Study 19168237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16135164 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 10411700 — Surrogate Endpoint (SUR): Blood pressure
Study 7550179 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28872914 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11030869 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11030869 — Safety Biomarker (SAF): Interleukin 1
Study 9302369 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8287572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8287572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8287572 — Safety Biomarker (SAF): Interleukin 1
Study 30801744 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 22487033 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 19038848 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19038848 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study 28892558 — Predictive Biomarker (PRD): MAP3K5 mRNA
Genes: MAP3K5; ASK1; MAPKKK5; MEKK5
Study 22644776 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22644776 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 8629587 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26751635 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 26751635 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25222490 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25222490 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25222490 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 21856047 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9820444 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7714065 — Surrogate Endpoint (SUR): Bone mineral density
Study 29298622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29298622 — Safety Biomarker (SAF): IL-6 and IL-10
Study 28879245 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 19706240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19706240 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16773176 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 10717011 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 10717011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2870226 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 2975549 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31454829 — Surrogate Endpoint (SUR): Serum creatinine
Study 28475456 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 23276359 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23276359 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 21477037 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 18679669 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16434127 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 3982273 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29623447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29623447 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29623447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29925316 — Surrogate Endpoint (SUR): Blood pressure
Study 20497755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20497755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15751771 — Surrogate Endpoint (SUR): Blood pressure
Study 15751771 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9571600 — Surrogate Endpoint (SUR): Bone mineral density
Study 7803550 — Surrogate Endpoint (SUR): Blood pressure
Study 2846947 — Surrogate Endpoint (SUR): Blood pressure
Study 2846947 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17027149 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 11127853 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7981178 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7981178 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 4570671 — Surrogate Endpoint (SUR): Blood pressure
Study 21516735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21516735 — Safety Biomarker (SAF): IL-6 and IL-10
Study 11935032 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 11935032 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 14764444 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11043499 — Surrogate Endpoint (SUR): Blood pressure
Study 25195352 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25195352 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25195352 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26728978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22111330 — Surrogate Endpoint (SUR): Blood pressure
Study 19434801 — Safety Biomarker (SAF): MTHFR
Study 17728218 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24659891 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 22877848 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 20843910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16091766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28124502 — Surrogate Endpoint (SUR): Blood pressure
Study 28124502 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25479835 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 23898612 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1960553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1960553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7200788 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31426321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26218728 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 31893232 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16368054 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 1751444 — Surrogate Endpoint (SUR): Blood pressure
Study 15807452 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 15807452 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 18942248 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12678218 — Surrogate Endpoint (SUR): Blood pressure
Study 1534001 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23825078 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23825078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17300591 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11979054 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11477843 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23034059 — Surrogate Endpoint (SUR): Blood pressure
Study 19244039 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19244039 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25281353 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 25281353 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 25281353 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 25281353 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 21084392 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19335977 — Monitoring Biomarker (MOI): HBV DNA
Study 17602082 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 31163689 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 31163689 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7715469 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26192892 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11396752 — Surrogate Endpoint (SUR): Serum creatinine
Study 9430254 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9430254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9430254 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 3390053 — Surrogate Endpoint (SUR): Blood pressure
Study 28058753 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8697160 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8697160 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8697160 — Surrogate Endpoint (SUR): Blood pressure
Study 8697160 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11531947 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11531947 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30669587 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23648395 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19624605 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27005961 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22805467 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 21280458 — Surrogate Endpoint (SUR): Blood pressure
Study 12551866 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2140970 — Safety Biomarker (SAF): L-acetylcarnitine
Study 28474783 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 7904489 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30592991 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 30592991 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 9818851 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 7859897 — Surrogate Endpoint (SUR): Blood pressure
Study 2760170 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 2760170 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2760170 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 6161 — Surrogate Endpoint (SUR): Blood pressure
Study 31392559 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 23847256 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 23847256 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 23847256 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 8471832 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26818900 — Surrogate Endpoint (SUR): Blood pressure
Study 18564342 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16612469 — Surrogate Endpoint (SUR): Blood pressure
Study 1797521 — Surrogate Endpoint (SUR): Blood pressure
Study 31987519 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31987519 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30747773 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 30747773 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 25500489 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21756381 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 10653828 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3723261 — Surrogate Endpoint (SUR): Serum sodium
Study 31702432 — Surrogate Endpoint (SUR): Pathological complete response
Study 27181606 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 24084500 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 20738227 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 18219298 — Surrogate Endpoint (SUR): Blood pressure
Study 12908569 — Surrogate Endpoint (SUR): Blood pressure
Study 3902911 — Surrogate Endpoint (SUR): Blood pressure
Study 29228369 — Surrogate Endpoint (SUR): Blood pressure
Study 28940820 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 23135529 — Surrogate Endpoint (SUR): Blood pressure
Study 22992449 — Surrogate Endpoint (SUR): Blood pressure
Study 7579506 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23800503 — Surrogate Endpoint (SUR): Blood pressure
Study 9579769 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 9579769 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9579769 — Surrogate Endpoint (SUR): Blood pressure
Study 7666079 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29066877 — Surrogate Endpoint (SUR): Bone mineral density
Study 31879812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31879812 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31879812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18557720 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 18557720 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3521619 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 3521619 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22932944 — Surrogate Endpoint (SUR): Blood pressure
Study 17646564 — Surrogate Endpoint (SUR): Blood pressure
Study 12526280 — Surrogate Endpoint (SUR): Blood pressure
Study 15585144 — Surrogate Endpoint (SUR): Serum creatinine
Study 25028375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20819415 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 15882537 — Surrogate Endpoint (SUR): Blood pressure
Study 27899759 — Surrogate Endpoint (SUR): Blood pressure
Study 8138828 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8138828 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 27264120 — Predictive Biomarker (PRD): Hormone receptor
Study 12441222 — Surrogate Endpoint (SUR): Blood pressure
Study 12441222 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27811309 — Surrogate Endpoint (SUR): Blood pressure
Study 17950796 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12110818 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 6165255 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28947390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24606094 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10408592 — Surrogate Endpoint (SUR): Blood pressure
Study 31905410 — Safety Biomarker (SAF): Hyaluronic acid
Study 19499845 — Surrogate Endpoint (SUR): Blood pressure
Study 1385586 — Surrogate Endpoint (SUR): Serum calcium
Study 30808670 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 29278896 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 29278896 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 29278896 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25186922 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19618659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19618659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11642085 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2723121 — Surrogate Endpoint (SUR): Blood pressure
Study 2723121 — Surrogate Endpoint (SUR): Serum uric acid
Study 27696393 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 22963131 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17540215 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15384808 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7285499 — Surrogate Endpoint (SUR): Serum potassium
Study 28857336 — Surrogate Endpoint (SUR): Blood pressure
Study 22976263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22976263 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22976263 — Safety Biomarker (SAF): Interleukin 1
Study 9261032 — Surrogate Endpoint (SUR): Blood pressure
Study 16705719 — Surrogate Endpoint (SUR): Bone mineral density
Study 11501728 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18583261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18583261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10217372 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10217372 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 19969423 — Predictive Biomarker (PRD): DHDDS mRNA
Genes: DHDDS; HDS
Study 17590368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15452586 — Predictive Biomarker (PRD): HSPA8 mRNA
Genes: HSPA8; HSC70; HSP73; HSPA10
Study 27860460 — Safety Biomarker (SAF): Interleukin 1
Study 17475960 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26812050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26812050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18422391 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12519437 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12519437 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 18419349 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31163519 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28893134 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 27808277 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 27808277 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21483000 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 21483000 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 31937026 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18599554 — Predictive Biomarker (PRD): CD93 mRNA
Genes: CD93; C1QR1; MXRA4
Study 18599554 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 18599554 — Predictive Biomarker (PRD): CDKN2B mRNA
Genes: CDKN2B; MTS2
Study 7021412 — Surrogate Endpoint (SUR): Blood pressure
Study 30190369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30190369 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 30190369 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30190369 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR