TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17452147 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 2653622 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2653622 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19701833 — Surrogate Endpoint (SUR): Blood pressure
Study 19701833 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26093871 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26093871 — Surrogate Endpoint (SUR): Serum creatinine
Study 9657579 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29622506 — Surrogate Endpoint (SUR): Blood pressure
Study 29622506 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27197288 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 17668874 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7197116 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21724838 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 11846327 — Surrogate Endpoint (SUR): Bone mineral density
Study 25713280 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23007142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23007142 — Surrogate Endpoint (SUR): Blood pressure
Study 2449904 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 26302850 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 23966145 — Surrogate Endpoint (SUR): Blood pressure
Study 14633951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25170938 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 25170938 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25170938 — Surrogate Endpoint (SUR): Bone mineral density
Study 21868752 — Surrogate Endpoint (SUR): Sperm parameters
Study 20620692 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24342768 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 20085630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 20085630 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 9581210 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 30830654 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30830654 — Surrogate Endpoint (SUR): Serum creatinine
Study 26500462 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 24274431 — Surrogate Endpoint (SUR): Blood pressure
Study 21450630 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21306953 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21306953 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11564594 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11564594 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27581221 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15954954 — Surrogate Endpoint (SUR): Blood pressure
Study 10526912 — Surrogate Endpoint (SUR): Blood pressure
Study 7398139 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29221491 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 20449626 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 18179324 — Surrogate Endpoint (SUR): Blood pressure
Study 25091615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30415601 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27243927 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 6751091 — Surrogate Endpoint (SUR): Blood pressure
Study 21721351 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 8029808 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 25258197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25258197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25258197 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16480401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24407182 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7568623 — Surrogate Endpoint (SUR): Blood pressure
Study 26027222 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 24166792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24166792 — Safety Biomarker (SAF): MTHFR
Study 7646919 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28029409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21272399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21272399 — Surrogate Endpoint (SUR): Blood pressure
Study 21272399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19581618 — Surrogate Endpoint (SUR): Blood pressure
Study 2893634 — Surrogate Endpoint (SUR): Blood pressure
Study 30143316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23739902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23739902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18703812 — Surrogate Endpoint (SUR): Blood pressure
Study 26910661 — Safety Biomarker (SAF): Hyaluronic acid
Study 16041725 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16041725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16041725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30407329 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30407329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30407329 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30407329 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26275544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12723744 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 30909945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27677411 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 25862215 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 25862215 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25862215 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23541571 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17109335 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24067888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15671089 — Surrogate Endpoint (SUR): Blood pressure
Study 15671089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7593499 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2299810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2299810 — Safety Biomarker (SAF): Interleukin 1
Study 25047038 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 22232454 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 18691193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31828172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31828172 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 31828172 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 28941598 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 24844538 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 29018897 — Surrogate Endpoint (SUR): Bone mineral density
Study 16398424 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16398424 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16398424 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16398424 — Safety Biomarker (SAF): Interleukin 1
Study 16398424 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16398424 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 16398424 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7895421 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20947241 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17111685 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3709640 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3709640 — Surrogate Endpoint (SUR): Blood pressure
Study 29262271 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 16182898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11927130 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28279316 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23011409 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 20625691 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18202564 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25744274 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25744274 — Surrogate Endpoint (SUR): Blood pressure
Study 20551461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11830525 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 2632716 — Surrogate Endpoint (SUR): Blood pressure
Study 31636806 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25396334 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22994579 — Surrogate Endpoint (SUR): Blood pressure
Study 15996257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26727163 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 26727163 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23141853 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 15719745 — Surrogate Endpoint (SUR): Blood pressure
Study 15719745 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15719745 — Predictive Biomarker (PRD): NOS3 mRNA
Genes: NOS3
Study 8781290 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15358571 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9543153 — Surrogate Endpoint (SUR): Blood pressure
Study 3054280 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 30086709 — Surrogate Endpoint (SUR): Blood pressure
Study 25399973 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24349389 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 12629105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10656431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 10656431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8679790 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8679790 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 23284689 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 22431901 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22431901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27502807 — Surrogate Endpoint (SUR): Blood pressure
Study 19718561 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10996354 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 10996354 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 8151105 — Monitoring Biomarker (MOI): HBV DNA
Study 3731535 — Surrogate Endpoint (SUR): Blood pressure
Study 21252701 — Surrogate Endpoint (SUR): Blood pressure
Study 17315536 — Surrogate Endpoint (SUR): Blood pressure
Study 9174309 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31923551 — Safety Biomarker (SAF): Interleukin 1
Study 24292746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23094808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15708879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31544290 — Surrogate Endpoint (SUR): Serum sodium
Study 26499270 — Surrogate Endpoint (SUR): Bone mineral density
Study 24138536 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24138536 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17260315 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9504953 — Surrogate Endpoint (SUR): Serum calcium
Study 2563787 — Surrogate Endpoint (SUR): Blood pressure
Study 30899086 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 30899086 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22947546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28297698 — Surrogate Endpoint (SUR): Blood pressure
Study 7947595 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 7947595 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27530473 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 25069476 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 25069476 — Predictive Biomarker (PRD): SLC28A1 mRNA
Genes: SLC28A1; CNT1
Study 11378006 — Surrogate Endpoint (SUR): Blood pressure
Study 15381054 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 1371211 — Surrogate Endpoint (SUR): Serum creatinine
Study 1371211 — Surrogate Endpoint (SUR): Blood pressure
Study 29908826 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19328438 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9916605 — Surrogate Endpoint (SUR): Blood pressure
Study 29472265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31416769 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31416769 — Surrogate Endpoint (SUR): Blood pressure
Study 22137134 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 28962869 — Surrogate Endpoint (SUR): Blood pressure
Study 20864904 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7479231 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7479231 — Surrogate Endpoint (SUR): Blood pressure
Study 2129319 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2129319 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30982356 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 29871204 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 25521103 — Safety Biomarker (SAF): Hyaluronic acid
Study 23344712 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23344712 — Surrogate Endpoint (SUR): Blood pressure
Study 26868683 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 24852464 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 22573238 — Surrogate Endpoint (SUR): Blood pressure
Study 15178637 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15178637 — Predictive Biomarker (PRD): NOS3 mRNA
Genes: NOS3
Study 7651063 — Surrogate Endpoint (SUR): Blood pressure
Study 31511041 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 9047153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3530049 — Surrogate Endpoint (SUR): Blood pressure
Study 23289013 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10911766 — Safety Biomarker (SAF): MTHFR
Study 10911766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8656390 — Safety Biomarker (SAF): Hyaluronic acid
Study 8319838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7490838 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 1586932 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28787243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28787243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10480616 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21811291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21811291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21811291 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20184573 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16112646 — Predictive Biomarker (PRD): PASD1 mRNA
Genes: PASD1
Study 16112646 — Predictive Biomarker (PRD): SSX2IP mRNA
Genes: SSX2IP; KIAA0923
Study 11866684 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 29901484 — Surrogate Endpoint (SUR): Blood pressure
Study 17361125 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11926718 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 2744187 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 2744187 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 30919998 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11730823 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11730823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31558010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31558010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31558010 — Safety Biomarker (SAF): Hyaluronic acid
Study 15571955 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 15571955 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26867060 — Surrogate Endpoint (SUR): Blood pressure
Study 11994249 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 11939055 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15459137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26082390 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19327776 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19327776 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8496462 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23179896 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23179896 — Surrogate Endpoint (SUR): Blood pressure
Study 28855568 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 28855568 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23697964 — Surrogate Endpoint (SUR): Blood pressure
Study 15303109 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 6319151 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9535215 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24630935 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 22341380 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21126615 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21126615 — Surrogate Endpoint (SUR): Serum uric acid
Study 21126615 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7029384 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 30167782 — Predictive Biomarker (PRD): SP4 mRNA
Genes: SP4
Study 28089366 — Surrogate Endpoint (SUR): Blood pressure
Study 11919121 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11919121 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 27215244 — Surrogate Endpoint (SUR): Serum potassium
Study 18193707 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15161956 — Surrogate Endpoint (SUR): Serum creatinine