TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02624050 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02624050 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02235675 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT02308527 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02308527 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03828422 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT01025349 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01025349 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05367739 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02342613 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT03854318 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT03669211 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03822468 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03822468 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03822468 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03502668 — Surrogate Endpoint (SUR): Hematologic response
Study NCT04439201 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study NCT04439201 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04439201 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT00027274 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT03329690 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03842917 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03842917 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03869450 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03823053 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00778817 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study NCT04530188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01044914 — Predictive Biomarker (PRD): XPR1 mRNA
Genes: XPR1; SYG1; XR
Study NCT02407405 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT02407405 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT04620382 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02567682 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT02567682 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02567682 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT02567682 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04564612 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01643850 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02805153 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04174989 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT04829773 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT06773429 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03855631 — Predictive Biomarker (PRD): KMT2D mRNA
Genes: KMT2D; ALR; MLL2; MLL4
Study NCT02701972 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study NCT03986879 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01317537 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01420874 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01390779 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00688246 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01087294 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04181060 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02193282 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02193282 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02538562 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02629120 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01120613 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03739814 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03188835 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study NCT03342742 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT04042376 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03690492 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04591197 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04591197 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00735826 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study NCT00735826 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study NCT00735826 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00735826 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study NCT00735826 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT02388594 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT01445522 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04424992 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00858897 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02211768 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT02211768 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT04356729 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01494298 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02584933 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04466267 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04466267 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00591149 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00591149 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00420940 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02324140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02324140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00532285 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02705014 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study NCT03515551 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00005333 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04542824 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03216304 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT02659020 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT04449874 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02271191 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT03356249 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02724319 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04009447 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05819333 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01434394 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06605326 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01054040 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04516083 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study NCT04516083 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT01831726 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01831726 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01831726 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01831726 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT02403635 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04432766 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01692860 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01596881 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01593995 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01593995 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00233051 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT03440918 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01524159 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01524159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03442257 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03442257 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03668054 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01457950 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01819558 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT03436641 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03866538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02337530 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04052438 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study NCT01166958 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01866423 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02181101 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03350139 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT01448824 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT01448824 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01448824 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04492709 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04150731 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT02630420 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02630420 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04035863 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04035863 — Safety Biomarker (SAF): BDNF
Study NCT00199784 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01262482 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT01262482 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01262482 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT01262482 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00748995 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00045747 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study NCT03351608 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT03778346 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03778346 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT03778346 — Predictive Biomarker (PRD): IL7 mRNA
Genes: IL7
Study NCT03778346 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study NCT03633630 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02679859 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03471533 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02578927 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03040635 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT00922883 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT02741700 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03144882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03144882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03833271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00506155 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01018199 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01018199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01017536 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03266120 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00913991 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03115853 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03115853 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT01243359 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01243359 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00037817 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04621214 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04621214 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT04056195 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study NCT04056195 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study NCT01524627 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT03777969 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT03777969 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00321958 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study NCT03525184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01894269 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02826356 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05504629 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02419118 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT03381482 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03752190 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02184221 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02980146 — Predictive Biomarker (PRD): KLRD1 mRNA
Genes: KLRD1; CD94
Study NCT02980146 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT01247090 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT00368264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00264641 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02783040 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02783040 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02783040 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03801564 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02143908 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT03642392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03772847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03772847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03662984 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03662984 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT03662984 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03663127 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03663127 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02227173 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT04004442 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT02179762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04693104 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03817333 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01218100 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02178813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00932620 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03068416 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00694096 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00006294 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00006294 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01268111 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study NCT01430507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01027481 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01027481 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00359333 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02337972 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03239470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01748253 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04516499 — Predictive Biomarker (PRD): RTN1 mRNA
Genes: RTN1; NSP
Study NCT00889954 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study NCT00889954 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03238911 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00079924 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05172453 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00000429 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05256121 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02220023 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02220023 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01872260 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT01872260 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00983515 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01217970 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01757626 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02625961 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04200807 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04371640 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00644904 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01126996 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study NCT02795559 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02745782 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01510015 — Safety Biomarker (SAF): DRD2
Study NCT01245738 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01245738 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04627181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04046315 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT01229072 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT03503903 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04384445 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03935633 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01212718 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT03818165 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03451565 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01907828 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03444974 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT03580642 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03317431 — Predictive Biomarker (PRD): DRD1 mRNA
Genes: DRD1
Study NCT03317431 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT03773133 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study NCT01625455 — Predictive Biomarker (PRD): TACR1 mRNA
Genes: TACR1; NK1R; TAC1R
Study NCT03384121 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study NCT03384121 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3