TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00277290 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT00277290 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT03218007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03814291 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03814291 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02066974 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT02066974 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT03138395 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study NCT03138395 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03134820 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03642236 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03642236 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04643548 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03965533 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study NCT03442907 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00867425 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01096121 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00926874 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00825045 — Safety Biomarker (SAF): DRD2
Study NCT02068586 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00244946 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00244946 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03487861 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study NCT01428453 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01428453 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT03945487 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00179400 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT01338545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02703909 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT02085733 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02085733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04850690 — Predictive Biomarker (PRD): MARCKS mRNA
Genes: MARCKS; MACS; PRKCSL
Study NCT04378842 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03657706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT01453634 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT03219294 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT04166435 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03876912 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03833973 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT03833973 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT03863223 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03446742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03446742 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01998633 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT01998633 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study NCT04397822 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT03736356 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00499018 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study NCT03949205 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03964155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02089633 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study NCT02432534 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT06547697 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06547697 — Surrogate Endpoint (SUR): Serum sodium
Study NCT00795444 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT03363360 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00000381 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT04034381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00795756 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00795756 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01994135 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01994135 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03893422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03863990 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03863990 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03863990 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04326348 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT06318793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03350633 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT03350633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03349749 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00875225 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01359657 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT01359657 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT00534274 — Predictive Biomarker (PRD): TK1 mRNA
Genes: TK1
Study NCT00362115 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01558752 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01927666 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study NCT02649907 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00681655 — Predictive Biomarker (PRD): GABRA2 mRNA
Genes: GABRA2
Study NCT01534585 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01534585 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05273424 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03597958 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT01656590 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04291391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04291391 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04291391 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03282942 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04324060 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT02448654 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02677922 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT02677922 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT01166178 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03465241 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00160940 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00084981 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT03500380 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02054286 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02757326 — Predictive Biomarker (PRD): SPHK2 mRNA
Genes: SPHK2; SK2
Study NCT04573894 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03879655 — Predictive Biomarker (PRD): NPC1 mRNA
Genes: NPC1
Study NCT00612664 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT01423123 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00603551 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04466254 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04466254 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT03109301 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT03109301 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01682811 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00904657 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00904657 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01840306 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01255137 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04005352 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04005352 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04959773 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04959773 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02771288 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT02708771 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00457483 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04414618 — Predictive Biomarker (PRD): SPHK2 mRNA
Genes: SPHK2; SK2
Study NCT03778684 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04873141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00623233 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01207765 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02236234 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02123771 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT01390974 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT02456207 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02456207 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02520869 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT03209817 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00842205 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT02211443 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02211443 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04791215 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01935349 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00213941 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study NCT00451243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00451243 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT00451243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03697031 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02494167 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT02494167 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study NCT01652989 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04539912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04539912 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT02304666 — Safety Biomarker (SAF): Pantetheinase
Genes: VNN1
Study NCT02099565 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00407368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04875377 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT01188902 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02750956 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02750956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02750956 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04053725 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT01644617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03425305 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00738257 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02871323 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01549132 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01960335 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03420508 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05509647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03149796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03149796 — Safety Biomarker (SAF): miR-9
Study NCT03149796 — Safety Biomarker (SAF): miR-16
Study NCT03149796 — Pharmacodynamic Biomarker (PDY): miR-132
Genes: MIR132
Study NCT03149796 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study NCT03149796 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-150
Genes: MIR150
Study NCT03149796 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT03149796 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study NCT02033031 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02033031 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00104572 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03531307 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT04320381 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01813539 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT02969824 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT00887354 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01710033 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT00351767 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01356966 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00203736 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study NCT00203736 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study NCT02870517 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03108885 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT01763112 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00991874 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02975947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00399633 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT00005465 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00004263 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study NCT01899612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04464070 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT03370380 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00273897 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT03672591 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03672591 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03786783 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02136797 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02063854 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00383149 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00383149 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04019314 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PENK mRNA
Genes: PENK
Study NCT02225340 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02225340 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study NCT02864251 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02864251 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04059679 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT02870660 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT02870660 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02870660 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04382573 — Predictive Biomarker (PRD): CDK13 mRNA
Genes: CDK13; CDC2L; CDC2L5; CHED; KIAA1791
Study NCT03394287 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00483379 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT03310372 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03954951 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02502539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03479099 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01066247 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05884047 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00196716 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT00916747 — Predictive Biomarker (PRD): ZMPSTE24
Genes: FACE-1; Ste24p; STE24; HGPS; PRO1
Study NCT00532584 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT02360592 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01374087 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00206414 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00624052 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03583138 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02653560 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02941445 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01968590 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01968590 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01759030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03376854 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study NCT03556007 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT02602860 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study NCT01758783 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01717404 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study NCT01918904 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT00243789 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02029833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05988047 — Predictive Biomarker (PRD): CMTM6 mRNA
Genes: CMTM6; CKLFSF6
Study NCT01108601 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03959293 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03959293 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03959293 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03959293 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT00898157 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT00149084 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00303498 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT01741922 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03933787 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT03933787 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00103142 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01396707 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03680365 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04698720 — Predictive Biomarker (PRD): MED28 mRNA
Genes: MED28; EG1; FKSG20
Study NCT05735392 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03375918 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02436356 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01537510 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02596581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2