TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12193818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29566443 — Surrogate Endpoint (SUR): Blood pressure
Study 18413496 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18413496 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18413496 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15831773 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 15831773 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8998248 — Surrogate Endpoint (SUR): Blood pressure
Study 25958079 — Surrogate Endpoint (SUR): Serum calcium
Study 25958079 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 25958079 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25958079 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25958079 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23650950 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23650950 — Surrogate Endpoint (SUR): Serum creatinine
Study 23650950 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 9445301 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9445301 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 28685911 — Surrogate Endpoint (SUR): Blood pressure
Study 19015329 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17314111 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11885871 — Surrogate Endpoint (SUR): Blood pressure
Study 8167511 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20145176 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8194495 — Surrogate Endpoint (SUR): Blood pressure
Study 18025536 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11292279 — Surrogate Endpoint (SUR): Blood pressure
Study 25970116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25970116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23234647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23234647 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8221741 — Surrogate Endpoint (SUR): Blood pressure
Study 22072084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12540640 — Surrogate Endpoint (SUR): Serum creatinine
Study 10100068 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10100068 — Surrogate Endpoint (SUR): Blood pressure
Study 10100068 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2006235 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 6344611 — Surrogate Endpoint (SUR): Blood pressure
Study 25166750 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19293312 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 2913769 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2913769 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10763145 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31166081 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 31166081 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24279026 — Surrogate Endpoint (SUR): Bacterial count
Study 9080151 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 9080151 — Surrogate Endpoint (SUR): Blood pressure
Study 9080151 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24646311 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16549945 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9185751 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 17888202 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 17888202 — Predictive Biomarker (PRD): GCLC mRNA
Genes: GCLC; GLCL; GLCLC
Study 17888202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 9497213 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 9497213 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 7961545 — Surrogate Endpoint (SUR): Blood pressure
Study 31755939 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 20642550 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20642550 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31804424 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 26501782 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26501782 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 9648992 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2537340 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14988614 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28350929 — Surrogate Endpoint (SUR): Serum calcium
Study 15138958 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8301432 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2500040 — Surrogate Endpoint (SUR): Blood pressure
Study 16883311 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16883311 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27979046 — Surrogate Endpoint (SUR): Blood pressure
Study 26028058 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20220206 — Safety Biomarker (SAF): MTHFR
Study 10188752 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10188752 — Surrogate Endpoint (SUR): Blood pressure
Study 2531153 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24997614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24997614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24997614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8450243 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24805282 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 17703218 — Surrogate Endpoint (SUR): Blood pressure
Study 12422064 — Surrogate Endpoint (SUR): Blood pressure
Study 8952580 — Surrogate Endpoint (SUR): Blood pressure
Study 30329163 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 11546945 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22348983 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 22348983 — Surrogate Endpoint (SUR): Bone mineral density
Study 10563706 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1677822 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30007039 — Surrogate Endpoint (SUR): Probing pocket depth
Study 30201456 — Surrogate Endpoint (SUR): Blood pressure
Study 26787231 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 22166897 — Surrogate Endpoint (SUR): Blood pressure
Study 22166897 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15015149 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15015149 — Surrogate Endpoint (SUR): Blood pressure
Study 15015149 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9645977 — Surrogate Endpoint (SUR): Blood pressure
Study 26597211 — Surrogate Endpoint (SUR): Blood pressure
Study 22371887 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 17537289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11897434 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31390002 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 16769988 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21258804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16377919 — Surrogate Endpoint (SUR): Serum potassium
Study 28003041 — Surrogate Endpoint (SUR): Serum creatinine
Study 28003041 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28003041 — Surrogate Endpoint (SUR): Serum potassium
Study 18302501 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 2021128 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8200988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18164013 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 18164013 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 31748594 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21969011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11529585 — Surrogate Endpoint (SUR): Blood pressure
Study 21551462 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12674333 — Safety Biomarker (SAF): MTHFR
Study 12674333 — Surrogate Endpoint (SUR): Bone mineral density
Study 7372036 — Surrogate Endpoint (SUR): Blood pressure
Study 7372036 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24798710 — Surrogate Endpoint (SUR): Blood pressure
Study 20921939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20921939 — Monitoring Biomarker (MOI): HBV DNA
Study 16624688 — Surrogate Endpoint (SUR): Blood pressure
Study 12515871 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10428524 — Surrogate Endpoint (SUR): Bone mineral density
Study 1692687 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29354990 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 23417203 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 31770012 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17328356 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 8138330 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27282133 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 27282133 — Surrogate Endpoint (SUR): Blood pressure
Study 24722774 — Surrogate Endpoint (SUR): Bone mineral density
Study 19083404 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10518002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30450601 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30450601 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23032205 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 23032205 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16114163 — Surrogate Endpoint (SUR): Blood pressure
Study 7587740 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7587740 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 7587740 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7587740 — Predictive Biomarker (PRD): CD58 mRNA
Genes: CD58; LFA3
Study 7188827 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 7052000 — Surrogate Endpoint (SUR): Serum potassium
Study 25377907 — Surrogate Endpoint (SUR): Bone mineral density
Study 20101013 — Surrogate Endpoint (SUR): Bone mineral density
Study 7488278 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26298832 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 9493932 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 23835824 — Surrogate Endpoint (SUR): Blood pressure
Study 20675956 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17283863 — Surrogate Endpoint (SUR): Blood pressure
Study 12805334 — Surrogate Endpoint (SUR): Hematologic response
Study 31246895 — Surrogate Endpoint (SUR): Blood pressure
Study 29902305 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 17852084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29947099 — Surrogate Endpoint (SUR): Blood pressure
Study 27362794 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19965915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18340009 — Predictive Biomarker (PRD): ACAT2 mRNA
Genes: ACAT2; ACTL
Study 18340009 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 18340009 — Predictive Biomarker (PRD): APOE mRNA
Genes: APOE
Study 7826828 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20629478 — Surrogate Endpoint (SUR): Bone mineral density
Study 17132757 — Surrogate Endpoint (SUR): Serum testosterone
Study 20027108 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16148457 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16148457 — Surrogate Endpoint (SUR): Blood pressure
Study 31838028 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18645345 — Surrogate Endpoint (SUR): Blood pressure
Study 17135607 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10735695 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26271204 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 23241227 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14630840 — Surrogate Endpoint (SUR): Bone mineral density
Study 24894416 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 24894416 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 24894416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10881265 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 6376207 — Surrogate Endpoint (SUR): Blood pressure
Study 6376207 — Surrogate Endpoint (SUR): Serum potassium
Study 31444995 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 31444995 — Predictive Biomarker (PRD): STN1 mRNA
Genes: STN1; OBFC1
Study 31444995 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 26443018 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 26443018 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10395628 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6941657 — Surrogate Endpoint (SUR): Blood pressure
Study 25369827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22901562 — Surrogate Endpoint (SUR): Blood pressure
Study 22901562 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17675054 — Surrogate Endpoint (SUR): Serum creatinine
Study 11328262 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9877109 — Surrogate Endpoint (SUR): Blood pressure
Study 2916485 — Predictive Biomarker (PRD): RAPH1 mRNA
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 9630829 — Surrogate Endpoint (SUR): Serum sodium
Study 27462118 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8635384 — Predictive Biomarker (PRD): Microsatellite instability
Study 30652260 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 16988133 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12802915 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12802915 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 12802915 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 12802915 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28537508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28537508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27179104 — Predictive Biomarker (PRD): CLEC9A mRNA
Genes: CLEC9A; UNQ9341/PRO34046
Study 18084691 — Surrogate Endpoint (SUR): Bone mineral density
Study 11140880 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 11140880 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 21508389 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21508389 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 21508389 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16669956 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7960013 — Surrogate Endpoint (SUR): Blood pressure
Study 26741384 — Safety Biomarker (SAF): Hyaluronic acid
Study 21080967 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 18207167 — Surrogate Endpoint (SUR): Blood pressure
Study 6308068 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6308068 — Surrogate Endpoint (SUR): Blood pressure
Study 26558729 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19342396 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 15133294 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15133294 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 15133294 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15133294 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15133294 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 12575588 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9782544 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9782544 — Surrogate Endpoint (SUR): Blood pressure
Study 23160920 — Surrogate Endpoint (SUR): Blood pressure
Study 10512904 — Surrogate Endpoint (SUR): Blood pressure
Study 7860749 — Surrogate Endpoint (SUR): Blood pressure
Study 6161534 — Predictive Biomarker (PRD): NAPA mRNA
Genes: NAPA; SNAPA
Study 31825471 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28169450 — Surrogate Endpoint (SUR): Bone mineral density
Study 27151378 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9649911 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 16998290 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 8513038 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30704429 — Surrogate Endpoint (SUR): Blood pressure
Study 26860800 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 26860800 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26860800 — Surrogate Endpoint (SUR): Blood pressure
Study 17545356 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6378439 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 6378439 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 6378439 — Surrogate Endpoint (SUR): Blood pressure
Study 20458350 — Surrogate Endpoint (SUR): Bone mineral density
Study 1643937 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 27964837 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25942458 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24991090 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 22029869 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 15449576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15449576 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15449576 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24646362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24646362 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24646362 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17531569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9930484 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25885807 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 22637738 — Surrogate Endpoint (SUR): Blood pressure
Study 22008920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22008920 — Surrogate Endpoint (SUR): Blood pressure
Study 16468059 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 8299527 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30989422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30989422 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26273134 — Safety Biomarker (SAF): Reactive oxygen species
Study 26273134 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 12656549 — Surrogate Endpoint (SUR): Blood pressure
Study 31145713 — Surrogate Endpoint (SUR): Blood pressure
Study 29550566 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27865358 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21951325 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19438927 — Surrogate Endpoint (SUR): Blood pressure
Study 15649723 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 12424509 — Surrogate Endpoint (SUR): Blood pressure
Study 10090633 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 10090633 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10090633 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7032828 — Surrogate Endpoint (SUR): Blood pressure