TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8164327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8164327 — Safety Biomarker (SAF): Interleukin 1
Study 16534549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10468218 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7644905 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25853905 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25853905 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25853905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21198560 — Surrogate Endpoint (SUR): Blood pressure
Study 20042080 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 11319170 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28725977 — Surrogate Endpoint (SUR): Bone mineral density
Study 17192770 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 14704836 — Surrogate Endpoint (SUR): Blood pressure
Study 11641511 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study 11641511 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 11641511 — Safety Biomarker (SAF): Interleukin 1
Study 24812898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24812898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10421597 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1683411 — Surrogate Endpoint (SUR): Blood pressure
Study 23298702 — Surrogate Endpoint (SUR): Blood pressure
Study 3518725 — Surrogate Endpoint (SUR): Blood pressure
Study 18325757 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18325757 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 14706764 — Surrogate Endpoint (SUR): Bone mineral density
Study 14706764 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31553765 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 31553765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31553765 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24555788 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 18201433 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 2505682 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 1187976 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19765497 — Surrogate Endpoint (SUR): Blood pressure
Study 15669554 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23713299 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23713299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23713299 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16600816 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16600816 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16600816 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16600816 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10867111 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 10867111 — Predictive Biomarker (PRD): Hormone receptor
Study 9263770 — Predictive Biomarker (PRD): PGM1 mRNA
Genes: PGM1
Study 30368939 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12404273 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9633494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15381116 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 15381116 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8506191 — Surrogate Endpoint (SUR): Blood pressure
Study 22617279 — Surrogate Endpoint (SUR): Blood pressure
Study 28062595 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 23896980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23896980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23896980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22321594 — Monitoring Biomarker (MOI): HBV DNA
Study 18927241 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11206684 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11206684 — Surrogate Endpoint (SUR): Blood pressure
Study 28392436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28392436 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28392436 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 21109557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11300383 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1725023 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1725023 — Surrogate Endpoint (SUR): Blood pressure
Study 29575637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29575637 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 29575637 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23652351 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 23652351 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 2685177 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24039738 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9330023 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 24453831 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 13678872 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10202683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 540459 — Surrogate Endpoint (SUR): Blood pressure
Study 31851556 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 31851556 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 17101560 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 17101560 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 23607773 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 20521988 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16182833 — Surrogate Endpoint (SUR): Serum creatinine
Study 1505563 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16421366 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1505293 — Surrogate Endpoint (SUR): Serum calcium
Study 30809971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18288274 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 18288274 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18288274 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 378509 — Surrogate Endpoint (SUR): Serum uric acid
Study 30010923 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 25642918 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 25642918 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 25642918 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 25642918 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 25642918 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 7541916 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7541916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30223023 — Safety Biomarker (SAF): Hyaluronic acid
Study 28341759 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28341759 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 28341759 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26667367 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23745525 — Safety Biomarker (SAF): Hyaluronic acid
Study 22768976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22768976 — Predictive Biomarker (PRD): Liver iron
Study 14712427 — Surrogate Endpoint (SUR): Bone mineral density
Study 14712427 — Surrogate Endpoint (SUR): Serum calcium
Study 29368152 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29368152 — Predictive Biomarker (PRD): Hormone receptor
Study 22377563 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 16555577 — Surrogate Endpoint (SUR): Blood pressure
Study 16555577 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10528960 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 6168837 — Surrogate Endpoint (SUR): Blood pressure
Study 31088856 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 8199724 — Surrogate Endpoint (SUR): Blood pressure
Study 31971474 — Predictive Biomarker (PRD): CRYAB mRNA
Genes: CRYAB; CRYA2; HSPB5
Study 31971474 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 26251666 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 26251666 — Surrogate Endpoint (SUR): Blood pressure
Study 7849541 — Surrogate Endpoint (SUR): Bone mineral density
Study 21884028 — Surrogate Endpoint (SUR): Blood pressure
Study 12663271 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 10052405 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31665115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15006256 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1421710 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 24586292 — Predictive Biomarker (PRD): COTL1 mRNA
Genes: COTL1; CLP
Study 7076881 — Surrogate Endpoint (SUR): Blood pressure
Study 24990880 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 20222106 — Surrogate Endpoint (SUR): Bone mineral density
Study 16959304 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9745993 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9745993 — Surrogate Endpoint (SUR): Blood pressure
Study 11962062 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 26908625 — Predictive Biomarker (PRD): SLC39A8 mRNA
Genes: SLC39A8; BIGM103; ZIP8; PP3105
Study 26908625 — Predictive Biomarker (PRD): POC1B mRNA
Genes: POC1B; WDR51B
Study 26908625 — Predictive Biomarker (PRD): GALNT4 mRNA
Genes: GALNT4
Study 26908625 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22914601 — Surrogate Endpoint (SUR): Blood pressure
Study 17148569 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 17148569 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 16311459 — Surrogate Endpoint (SUR): Blood pressure
Study 2186854 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 2186854 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22678100 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20966605 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18387222 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 11841418 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28177133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28177133 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12751274 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16613263 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 16613263 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 1827010 — Surrogate Endpoint (SUR): Blood pressure
Study 24385387 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19056706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15026402 — Surrogate Endpoint (SUR): Serum sodium
Study 3056505 — Surrogate Endpoint (SUR): Blood pressure
Study 20846961 — Surrogate Endpoint (SUR): Blood pressure
Study 16879679 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 12911659 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9108457 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20808854 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 20808854 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 10449882 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 24120550 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19808134 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 30453599 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8600545 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2010560 — Surrogate Endpoint (SUR): Blood pressure
Study 26309133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26309133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23208319 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23208319 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23208319 — Surrogate Endpoint (SUR): Blood pressure
Study 16972973 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 15610084 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 30858012 — Surrogate Endpoint (SUR): Blood pressure
Study 23930160 — Surrogate Endpoint (SUR): Blood pressure
Study 30862667 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 23698063 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21372309 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 11142481 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 26527417 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 19094432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19094432 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15663590 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 2350208 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 31478799 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23866850 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 23866850 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 19120333 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 19120333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16829185 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 11096237 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31733985 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20632084 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26273264 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31183514 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26493267 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26493267 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19491536 — Surrogate Endpoint (SUR): Blood pressure
Study 14763917 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11248662 — Surrogate Endpoint (SUR): Bone mineral density
Study 27194175 — Surrogate Endpoint (SUR): Blood pressure
Study 20377585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12503692 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12503692 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12503692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 335867 — Surrogate Endpoint (SUR): Blood pressure
Study 3890279 — Surrogate Endpoint (SUR): Blood pressure
Study 12843799 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12843799 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11007235 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 6494011 — Predictive Biomarker (PRD): RTN1 mRNA
Genes: RTN1; NSP
Study 26250966 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26250966 — Surrogate Endpoint (SUR): Serum sodium
Study 23915885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10883872 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29925930 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29925930 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19183127 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19183127 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9215520 — Surrogate Endpoint (SUR): Blood pressure
Study 28139405 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 16263817 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16263817 — Surrogate Endpoint (SUR): Serum testosterone
Study 31710134 — Surrogate Endpoint (SUR): Blood pressure
Study 24059116 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 21868346 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7486185 — Surrogate Endpoint (SUR): Blood pressure
Study 28471950 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 23398944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21290392 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 19118130 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 17185355 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 16761192 — Surrogate Endpoint (SUR): Blood pressure
Study 8408940 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19020919 — Surrogate Endpoint (SUR): Bone mineral density
Study 3363288 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30351172 — Surrogate Endpoint (SUR): Blood pressure
Study 3045113 — Surrogate Endpoint (SUR): Blood pressure
Study 31023863 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31023863 — Predictive Biomarker (PRD): EPHA5 mRNA
Genes: EPHA5; BSK; EHK1; HEK7; TYRO4
Study 31023863 — Predictive Biomarker (PRD): EPHA6 mRNA
Genes: EPHA6; EHK2; HEK12
Study 31023863 — Predictive Biomarker (PRD): EPHA8 mRNA
Genes: EPHA8; EEK; HEK3; KIAA1459
Study 26099758 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 21142269 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 21142269 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9022117 — Surrogate Endpoint (SUR): Blood pressure
Study 7910235 — Surrogate Endpoint (SUR): Blood pressure
Study 29985964 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27129624 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24803825 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24803825 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22044195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20488410 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15951469 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 7854523 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30295721 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 26380437 — Monitoring Biomarker (MOI): Procalcitonin
Study 26380437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26380437 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26380437 — Surrogate Endpoint (SUR): Serum creatinine
Study 26380437 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8039530 — Surrogate Endpoint (SUR): Serum testosterone
Study 2688711 — Surrogate Endpoint (SUR): Serum creatinine
Study 25122150 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 11707563 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19344226 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15601638 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25966138 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25966138 — Surrogate Endpoint (SUR): Blood pressure
Study 7950469 — Surrogate Endpoint (SUR): Blood pressure
Study 30549271 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF