TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27634203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27634566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27635072 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study 27636400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27637014 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 27637014 — Surrogate Endpoint (SUR): Blood pressure
Study 27637497 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27637985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 27637985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27639327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27642132 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 27642534 — Surrogate Endpoint (SUR): Bone mineral density
Study 27642534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27642534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27643438 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 27643438 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 27643485 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 27644469 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27644734 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27644734 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 27646946 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27647168 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 27648294 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 27648294 — Surrogate Endpoint (SUR): Pathological complete response
Study 27649801 — Surrogate Endpoint (SUR): Blood pressure
Study 27650283 — Monitoring Biomarker (MOI): HBV DNA
Study 27651390 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 27651793 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 27651793 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27652031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27652031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27654603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27655115 — Safety Biomarker (SAF): BDNF
Study 27655463 — Surrogate Endpoint (SUR): Bone mineral density
Study 27656840 — Predictive Biomarker (PRD): MAP1LC3B mRNA
Genes: MAP1LC3B; MAP1ALC3
Study 27657052 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 27657681 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27658437 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-150
Genes: MIR150
Study 27658437 — Safety Biomarker (SAF): miR-146b
Genes: MIR146B
Study 27658437 — Safety Biomarker (SAF): miR-1
Study 27658437 — Safety Biomarker (SAF): miR-150-5p
Genes: MIR150
Study 27658437 — Monitoring Biomarker (MOI): miR-146b-5p
Genes: MIR146B
Study 27658740 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27658740 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 27658740 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27658863 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27658863 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27659464 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27660108 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 27660108 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27661411 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27669027 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 27669027 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 27669027 — Predictive Biomarker (PRD): SOWAHB mRNA
Genes: SOWAHB; ANKRD56
Study 27669027 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 27669027 — Predictive Biomarker (PRD); Safety Biomarker (SAF): JCAD mRNA
Genes: JCAD; KIAA1462
Study 27669153 — Surrogate Endpoint (SUR): Bone mineral density
Study 27673576 — Surrogate Endpoint (SUR): Sperm parameters
Study 27677166 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27677442 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 27678432 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27680716 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 27681000 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27681000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27681799 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 27681866 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27682582 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 27682742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27682742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27683021 — Surrogate Endpoint (SUR): Blood pressure
Study 27683850 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 27692683 — Surrogate Endpoint (SUR): Blood pressure
Study 27692920 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27693556 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 27694141 — Safety Biomarker (SAF): Reactive oxygen species
Study 27695088 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27696724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27704266 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 27704266 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 27704266 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27704266 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 27706467 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 27706467 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27706467 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27707765 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27707765 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27707805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27707807 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27711228 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27716119 — Predictive Biomarker (PRD): GUCY2C mRNA
Genes: GUCY2C; GUC2C; STAR
Study 27716131 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 27716244 — Predictive Biomarker (PRD): HDGFL2 mRNA
Genes: HDGFL2; HDGF2; HDGFRP2; HRP2; UNQ785/PRO1604
Study 27716304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27716304 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 27716343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27716377 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27716377 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 27716377 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27716819 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 27717372 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 27717384 — Surrogate Endpoint (SUR): Serum creatinine
Study 27717384 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27717842 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 27719680 — Surrogate Endpoint (SUR): Blood pressure
Study 27719681 — Surrogate Endpoint (SUR): Blood pressure
Study 27720178 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 27722854 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27725657 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 27726853 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27729313 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27733374 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27733495 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study 27734949 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 27734949 — Predictive Biomarker (PRD): CTNS mRNA
Genes: CTNS
Study 27734949 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 27738920 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27740536 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27741031 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27742126 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27742581 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27742908 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27743502 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study 27745744 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27746093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27746093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27746690 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 27746690 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 27746690 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 27746690 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 27746690 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27747511 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 27747583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27748745 — Predictive Biomarker (PRD): METRNL mRNA
Genes: METRNL
Study 27749650 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 27749683 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 27749683 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27749683 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27749683 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27751676 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 27751847 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27755109 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27756308 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 27757709 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27760529 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27760758 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 27760758 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27760761 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 27764091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27764091 — Surrogate Endpoint (SUR): Blood pressure
Study 27764800 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 27764800 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27764800 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27765666 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27765757 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27766064 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 27768923 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27769214 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27771544 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 27771610 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27771610 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 27775823 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 27776526 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27776526 — Surrogate Endpoint (SUR): Blood pressure
Study 27777606 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27777873 — Surrogate Endpoint (SUR): Serum sodium
Study 27778639 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 27779248 — Predictive Biomarker (PRD): VSIG2 mRNA
Genes: VSIG2; CTH; CTXL; UNQ2770/PRO7154
Study 27779436 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27783539 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27784272 — Surrogate Endpoint (SUR): Blood pressure
Study 27787664 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 27788856 — Surrogate Endpoint (SUR): Blood pressure
Study 27789678 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 27789678 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 27789678 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 27790041 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27790763 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 27791128 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27791128 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27791347 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 27791347 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 27792741 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 27793105 — Surrogate Endpoint (SUR): Blood pressure
Study 27793850 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 27793850 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 27794402 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study 27797317 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27798032 — Surrogate Endpoint (SUR): Blood pressure
Study 27798339 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27799204 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 27799204 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 27799230 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 27799945 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27802546 — Predictive Biomarker (PRD): COL7A1 mRNA
Genes: COL7A1
Study 27803005 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 27803138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27805836 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 27807285 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 27809785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27809833 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27811203 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 27811504 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 27812547 — Surrogate Endpoint (SUR): Blood pressure
Study 27812547 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27814297 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27814709 — Safety Biomarker (SAF): Th2 cell
Study 27814712 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 27814717 — Predictive Biomarker (PRD): MAML1 mRNA
Genes: MAML1; KIAA0200
Study 27814763 — Predictive Biomarker (PRD): SP3 mRNA
Genes: SP3
Study 27815383 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27816492 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 27817208 — Surrogate Endpoint (SUR): Blood pressure
Study 27817208 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27820636 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 27821717 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27825374 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 27825374 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 27825374 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 27825374 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 27825374 — Predictive Biomarker (PRD): POU2F1 mRNA
Genes: POU2F1; OCT1; OTF1
Study 27825382 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 27825636 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 27826691 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 27826691 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 27826691 — Safety Biomarker (SAF): DRD2
Study 27828943 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27831501 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 27832753 — Surrogate Endpoint (SUR): Blood pressure
Study 27835869 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 27835869 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 27835869 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study 27835869 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27835869 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 27835869 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27836716 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27839651 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 27839651 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 27839979 — Surrogate Endpoint (SUR): Bone mineral density
Study 27843623 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27843623 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 27843623 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 27843625 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study 27846610 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 27846610 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27847367 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 27847634 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27847634 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27848182 — Predictive Biomarker (PRD): SLAMF7 mRNA
Genes: SLAMF7; CS1; UNQ576/PRO1138
Study 27849125 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27851688 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 27853379 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FasL mRNA
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 27855624 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 27855624 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27855684 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 27862700 — Surrogate Endpoint (SUR): Blood pressure
Study 27862721 — Monitoring Biomarker (MOI): HBV DNA
Study 27863192 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 27863192 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study 27863192 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27863194 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27863197 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27863201 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27864013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 27868471 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 27869650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 27869650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27869909 — Predictive Biomarker (PRD): SFRP4 mRNA
Genes: SFRP4; FRPHE
Study 27869909 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 27869909 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-34a
Genes: MIR34A