TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03608878 — Predictive Biomarker (PRD): GALNT14 mRNA
Genes: GALNT14; UNQ2434/PRO4994
Study NCT03159585 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00662753 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00669630 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03084393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02488551 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study NCT04396353 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02258009 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01986569 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT04758273 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04758273 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02758665 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02401958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02401958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02401958 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT02401958 — Safety Biomarker (SAF): Interleukin 1
Study NCT02401958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02401958 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT02401958 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT02106351 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT03174821 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03174821 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT00005986 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01425073 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02444819 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00726180 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00726180 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04241198 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00788775 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT02223143 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03951961 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00439673 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00277316 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT00277316 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01787006 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01787006 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03396536 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT02081378 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02081378 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04090281 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03287609 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03287609 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04478227 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT01700621 — Surrogate Endpoint (SUR): Serum antibody concentration
Study NCT01079624 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02334527 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT04410328 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01563978 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03516019 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02502110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02502110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02502110 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00334009 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT00334009 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00526786 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study NCT03488524 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT04248465 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT01173640 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00905021 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00425217 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03183557 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02164838 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02797028 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT04632277 — Surrogate Endpoint (SUR): Serum calcium
Study NCT04632277 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00586924 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT03156257 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study NCT01720316 — Predictive Biomarker (PRD): GLDC mRNA
Genes: GLDC; GCSP
Study NCT01695122 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT04243681 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04243681 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04243681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04243681 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT03157388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06336499 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT03732586 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT03732586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03732586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT03732586 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT00789477 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02881190 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02283658 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04483115 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00461825 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03287557 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02205437 — Safety Biomarker (SAF): DRD2
Study NCT00006708 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03611933 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00496444 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00496444 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT02681952 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03270293 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00268619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00268619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04472780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00973193 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00973193 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00593450 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02450773 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00823550 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04896164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04896164 — Safety Biomarker (SAF): Interleukin 1
Study NCT04896164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04896164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT04896164 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT02160379 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02160379 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT01941394 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01722916 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03233815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03233815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04043871 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01060020 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01471847 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01471847 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02809508 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02809508 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT00241137 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03045393 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT01373710 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01899118 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01899118 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01957696 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT03201302 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01490944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03338972 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03916094 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02116712 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT02396823 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05039502 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT03656484 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01221324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01221324 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03249064 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study NCT00861796 — Safety Biomarker (SAF): DRD2
Study NCT04808128 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02603783 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT01309607 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03836157 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT03560544 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03567642 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03567642 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study NCT03567642 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT00075348 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT01763905 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03001037 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT01129336 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00821132 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03955887 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT03955887 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT03622658 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01607216 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01157091 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05799300 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01520207 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01686685 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01686685 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT01686685 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01686685 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT04033978 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT01438619 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00243230 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT01057199 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study NCT02484560 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02054390 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01620853 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04142060 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04142060 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04142060 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04142060 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03570125 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03570125 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03570125 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT03070184 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT00493012 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01105104 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00994253 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03153215 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT02679248 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02418234 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02418234 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02418234 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03815838 — Safety Biomarker (SAF): DRD2
Study NCT02791555 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00424203 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01049191 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03481205 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02707978 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04263246 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03739320 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT00766597 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT04601142 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT04601142 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT04601142 — Predictive Biomarker (PRD): TBX21 mRNA
Genes: TBX21; TBET; TBLYM
Study NCT04601142 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study NCT03050398 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02590185 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT02590185 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02590185 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03118817 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03118817 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT02109094 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01226173 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study NCT05249296 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03983902 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03486899 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT00509899 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT03445000 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT00411788 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01293422 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study NCT00001493 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT00596102 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04581902 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00622232 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01865864 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01050946 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04842396 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06379230 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT05858203 — Predictive Biomarker (PRD): AATF mRNA
Genes: AATF; CHE1; DED; HSPC277
Study NCT02488382 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00969566 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01312922 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study NCT03354104 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT03227484 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT01228409 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT00103194 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03744637 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03744637 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00235573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02975180 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT00556127 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04986241 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00048581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00048581 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT04666909 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04374305 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT02622152 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02008968 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00566800 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01615068 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01049061 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT01570699 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT01346527 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01346527 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02268032 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00950937 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01147211 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01147211 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03079505 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03079505 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04346628 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00759824 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT03152617 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01096160 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002994 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00002994 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02166021 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04917549 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04917549 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04833517 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04366232 — Safety Biomarker (SAF): Interleukin 1
Study NCT04366232 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01495221 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02038179 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04078711 — Surrogate Endpoint (SUR): Blood pressure