TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9703286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 2915651 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 951456 — Surrogate Endpoint (SUR): Blood pressure
Study 27118225 — Surrogate Endpoint (SUR): Blood pressure
Study 19392925 — Surrogate Endpoint (SUR): Blood pressure
Study 8038592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8038592 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8038592 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 241876 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 241876 — Surrogate Endpoint (SUR): Blood pressure
Study 28646182 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28646182 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28646182 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 28646182 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 28646182 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 17932248 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 17932248 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 3323072 — Surrogate Endpoint (SUR): Blood pressure
Study 16458451 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 16458451 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16111499 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16111499 — Surrogate Endpoint (SUR): Blood pressure
Study 20043525 — Surrogate Endpoint (SUR): Blood pressure
Study 9150013 — Surrogate Endpoint (SUR): Blood pressure
Study 10192700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10192700 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 27342264 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 24176494 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21990397 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10709150 — Surrogate Endpoint (SUR): Blood pressure
Study 20921898 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8793607 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 30789154 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 18829069 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17173849 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 17173849 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 11549528 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 11549528 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 24314853 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 7898093 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7898093 — Surrogate Endpoint (SUR): Blood pressure
Study 21742094 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23406861 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15026584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15026584 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20461319 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17593515 — Surrogate Endpoint (SUR): Serum creatinine
Study 2222943 — Surrogate Endpoint (SUR): Blood pressure
Study 215097 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 27918764 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27918764 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27465372 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 18575077 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10398312 — Predictive Biomarker (PRD): NELFCD mRNA
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 10398312 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17580458 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 17370492 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11167372 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 11167372 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 44671 — Surrogate Endpoint (SUR): Blood pressure
Study 15472185 — Surrogate Endpoint (SUR): Bone mineral density
Study 27306892 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 27306892 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27306892 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 27306892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21959624 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 12592328 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 30718072 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30718072 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27131832 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 24947447 — Surrogate Endpoint (SUR): Blood pressure
Study 21744028 — Surrogate Endpoint (SUR): Serum creatinine
Study 15775795 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15775795 — Surrogate Endpoint (SUR): Blood pressure
Study 17178974 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31068954 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 17523274 — Monitoring Biomarker (MOI): Procalcitonin
Study 9172022 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29966024 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 29966024 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 29966024 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 29966024 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 29966024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 29966024 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 10546925 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29728394 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 29728394 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29728394 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16244022 — Surrogate Endpoint (SUR): Blood pressure
Study 8765865 — Surrogate Endpoint (SUR): Blood pressure
Study 1658407 — Predictive Biomarker (PRD): NDP mRNA
Genes: NDP; EVR2
Study 1658407 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17415683 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6366811 — Surrogate Endpoint (SUR): Blood pressure
Study 30415084 — Surrogate Endpoint (SUR): Blood pressure
Study 29852038 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22019201 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27677565 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9814500 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 21689069 — Surrogate Endpoint (SUR): Bone mineral density
Study 16835383 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 3093022 — Surrogate Endpoint (SUR): Serum calcium
Study 3093022 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 22650126 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 20435265 — Surrogate Endpoint (SUR): Bone mineral density
Study 18661187 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 17921832 — Surrogate Endpoint (SUR): Blood pressure
Study 27488272 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 9366277 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9366277 — Surrogate Endpoint (SUR): Blood pressure
Study 8347851 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8356979 — Surrogate Endpoint (SUR): Blood pressure
Study 8356979 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8356979 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23592936 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23592936 — Surrogate Endpoint (SUR): Blood pressure
Study 18417461 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1464126 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22730113 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 15767226 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9822140 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2697435 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 972274 — Surrogate Endpoint (SUR): Serum creatinine
Study 14735173 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 21983766 — Surrogate Endpoint (SUR): Blood pressure
Study 18434906 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18434906 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 16931217 — Surrogate Endpoint (SUR): Serum calcium
Study 16931217 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 16931217 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16931217 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16931217 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11110230 — Surrogate Endpoint (SUR): Blood pressure
Study 11110230 — Surrogate Endpoint (SUR): Serum uric acid
Study 12378193 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9385104 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 30008038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22458574 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 17687635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3334108 — Surrogate Endpoint (SUR): Serum creatinine
Study 31715671 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 29072166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22477032 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 22477032 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18050198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16286607 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28692172 — Surrogate Endpoint (SUR): Bone mineral density
Study 8470626 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 26967465 — Surrogate Endpoint (SUR): Bone mineral density
Study 18328120 — Surrogate Endpoint (SUR): Blood pressure
Study 10584979 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10584979 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10584979 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15554600 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15554600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15554600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15554600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29289621 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 29289621 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 29289621 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 29289621 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22233394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17963628 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19034732 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 8565031 — Surrogate Endpoint (SUR): Bone mineral density
Study 28209333 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24154935 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 14676992 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 14676992 — Surrogate Endpoint (SUR): Bone mineral density
Study 30354371 — Surrogate Endpoint (SUR): Blood pressure
Study 26791438 — Surrogate Endpoint (SUR): Sperm parameters
Study 31929472 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29668699 — Surrogate Endpoint (SUR): Blood pressure
Study 26103979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10741688 — Surrogate Endpoint (SUR): Bone mineral density
Study 28419650 — Surrogate Endpoint (SUR): Blood pressure
Study 15026871 — Surrogate Endpoint (SUR): Blood pressure
Study 18786981 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 11193233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11193233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30522806 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 17519075 — Safety Biomarker (SAF): Interleukin 12
Study 10606880 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 7750288 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7750288 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 15012046 — Surrogate Endpoint (SUR): Blood pressure
Study 11708421 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 11708421 — Surrogate Endpoint (SUR): Bone mineral density
Study 29111077 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29111077 — Safety Biomarker (SAF): BDNF
Study 21813912 — Surrogate Endpoint (SUR): Blood pressure
Study 10857950 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27440803 — Surrogate Endpoint (SUR): Serum creatinine
Study 26469916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23950186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15467309 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15467309 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15467309 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3275909 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3275909 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24711000 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 16995478 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16995478 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2168908 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8053744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26666258 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 17628642 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 17628642 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 12021573 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19638112 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 19638112 — Predictive Biomarker (PRD): RASA1 mRNA
Genes: RASA1; GAP; RASA
Study 3896085 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28531281 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 18986288 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 12813377 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 10930160 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22319901 — Surrogate Endpoint (SUR): Blood pressure
Study 10956377 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3533564 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3533564 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 3533564 — Surrogate Endpoint (SUR): Blood pressure
Study 29968301 — Predictive Biomarker (PRD): SMAD3 mRNA
Genes: SMAD3; MADH3
Study 29968301 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 18958840 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 18958840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18958840 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18958840 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 18958840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15973180 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 15973180 — Surrogate Endpoint (SUR): Bone mineral density
Study 24576512 — Surrogate Endpoint (SUR): Blood pressure
Study 18848937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12000246 — Surrogate Endpoint (SUR): Blood pressure
Study 27974124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27974124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27974124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25232263 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 15674409 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 7779130 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 22761759 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17621177 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9824003 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 31206768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31206768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31206768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28838644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15372414 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 29099236 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 22787176 — Surrogate Endpoint (SUR): Blood pressure
Study 11165356 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 2872803 — Surrogate Endpoint (SUR): Blood pressure
Study 15099916 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 31180194 — Predictive Biomarker (PRD): KLRG1 mRNA
Genes: KLRG1; CLEC15A; MAFA; MAFAL
Study 31180194 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 27974345 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 25566874 — Surrogate Endpoint (SUR): Blood pressure
Study 19364980 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19364980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19364980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19364980 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 27341326 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 26653113 — Predictive Biomarker (PRD): TACR3 mRNA
Genes: TACR3; NK3R; TAC3R
Study 8589208 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1720759 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 29759808 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 20563294 — Surrogate Endpoint (SUR): Blood pressure
Study 20563294 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15149896 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 9695721 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 7907646 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7907646 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30395904 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25724455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25724455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21992849 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21992849 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell