TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1820496 — Surrogate Endpoint (SUR): Blood pressure
Study 28116754 — Safety Biomarker (SAF): Hyaluronic acid
Study 25944731 — Surrogate Endpoint (SUR): Bone mineral density
Study 21811062 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21811062 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15549278 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 24074763 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23082382 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 2007841 — Surrogate Endpoint (SUR): Blood pressure
Study 31656505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31656505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31656505 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10973645 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 30278263 — Surrogate Endpoint (SUR): Blood pressure
Study 26719915 — Surrogate Endpoint (SUR): Blood pressure
Study 26719915 — Surrogate Endpoint (SUR): Serum potassium
Study 18065591 — Surrogate Endpoint (SUR): Blood pressure
Study 30657891 — Surrogate Endpoint (SUR): Blood pressure
Study 17227264 — Surrogate Endpoint (SUR): Blood pressure
Study 10745070 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10745070 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25198033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22744718 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8121319 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 16009466 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12580985 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12580985 — Surrogate Endpoint (SUR): Blood pressure
Study 11511426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11511426 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study 11825486 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24200335 — Surrogate Endpoint (SUR): Blood pressure
Study 24367946 — Predictive Biomarker (PRD): PALM mRNA
Genes: PALM; KIAA0270
Study 17935974 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21225277 — Surrogate Endpoint (SUR): Blood pressure
Study 19254810 — Predictive Biomarker (PRD): HSPA8 mRNA
Genes: HSPA8; HSC70; HSP73; HSPA10
Study 19254810 — Predictive Biomarker (PRD): DNAJB1 mRNA
Genes: DNAJB1; DNAJ1; HDJ1; HSPF1
Study 19254810 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 19254810 — Predictive Biomarker (PRD): FKBP4 mRNA
Genes: FKBP4; FKBP52
Study 15476449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28107844 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19861324 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8313746 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8313746 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8313746 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 3525424 — Surrogate Endpoint (SUR): Blood pressure
Study 15230823 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11824669 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2784322 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23072780 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11468003 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8289749 — Surrogate Endpoint (SUR): Blood pressure
Study 30171784 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30171784 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 30171784 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26771445 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 25376884 — Surrogate Endpoint (SUR): Blood pressure
Study 18635428 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17207282 — Surrogate Endpoint (SUR): Blood pressure
Study 23535252 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 9089856 — Surrogate Endpoint (SUR): Blood pressure
Study 31182766 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 23146638 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study 9552064 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31849123 — Predictive Biomarker (PRD): SFRP5 mRNA
Genes: SFRP5; FRP1B; SARP3
Study 29844808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25330169 — Surrogate Endpoint (SUR): Blood pressure
Study 17617938 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25166719 — Surrogate Endpoint (SUR): Bone mineral density
Study 25166719 — Surrogate Endpoint (SUR): Serum calcium
Study 17635944 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11079257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30402951 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 30402951 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 30402951 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28447186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28447186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28447186 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18388845 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 14578916 — Surrogate Endpoint (SUR): Blood pressure
Study 28102582 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 19478423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2423783 — Surrogate Endpoint (SUR): Blood pressure
Study 21931073 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2070134 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25928879 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 17108847 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 14742401 — Surrogate Endpoint (SUR): Blood pressure
Study 9623379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9623379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9623379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2176947 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21519764 — Surrogate Endpoint (SUR): Blood pressure
Study 16267371 — Surrogate Endpoint (SUR): Blood pressure
Study 24767232 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 15780537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8554932 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1824806 — Surrogate Endpoint (SUR): Blood pressure
Study 17257444 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 7649426 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2668784 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12637115 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23091097 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 12747810 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10561206 — Predictive Biomarker (PRD): Hormone receptor
Study 30511107 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28532866 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 26118755 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 11226644 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2911834 — Surrogate Endpoint (SUR): Blood pressure
Study 15029134 — Surrogate Endpoint (SUR): Blood pressure
Study 25374138 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24620386 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 24620386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24620386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24620386 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24620386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24620386 — Monitoring Biomarker (MOI): HBV DNA
Study 21933609 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14970007 — Surrogate Endpoint (SUR): Blood pressure
Study 11437096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9250454 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3613693 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 28639862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28639862 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11004613 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1296499 — Surrogate Endpoint (SUR): Blood pressure
Study 18258627 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16771810 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 8644642 — Surrogate Endpoint (SUR): Blood pressure
Study 12970227 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10391657 — Surrogate Endpoint (SUR): Blood pressure
Study 8675588 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 21172109 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 21368390 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21368390 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9822139 — Surrogate Endpoint (SUR): Blood pressure
Study 23547047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23547047 — Surrogate Endpoint (SUR): Serum testosterone
Study 3136086 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 2189839 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28264922 — Surrogate Endpoint (SUR): Blood pressure
Study 21358314 — Surrogate Endpoint (SUR): Blood pressure
Study 21358314 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14573726 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8934214 — Surrogate Endpoint (SUR): Blood pressure
Study 27379829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27379829 — Safety Biomarker (SAF): MTHFR
Study 17323595 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3517388 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30201101 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26650434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 25899445 — Surrogate Endpoint (SUR): Serum creatinine
Study 23537892 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18926433 — Surrogate Endpoint (SUR): Serum creatinine
Study 12690275 — Monitoring Biomarker (MOI): HBV DNA
Study 26951205 — Surrogate Endpoint (SUR): Blood pressure
Study 26951205 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26774673 — Predictive Biomarker (PRD): SLC23A2 mRNA
Genes: SLC23A2; KIAA0238; NBTL1; SLC23A1; SVCT2; YSPL2
Study 26774673 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22784030 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 22784030 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9428449 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9428449 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 8085374 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 1008247 — Surrogate Endpoint (SUR): Serum potassium
Study 1008247 — Surrogate Endpoint (SUR): Serum sodium
Study 20194455 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 11289091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11289091 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 3329207 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 3329207 — Surrogate Endpoint (SUR): Blood pressure
Study 26124907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26124907 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17402790 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17402790 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8738686 — Surrogate Endpoint (SUR): Blood pressure
Study 31843024 — Surrogate Endpoint (SUR): Blood pressure
Study 10731485 — Surrogate Endpoint (SUR): Blood pressure
Study 27974526 — Surrogate Endpoint (SUR): Blood pressure
Study 25280396 — Surrogate Endpoint (SUR): Bone mineral density
Study 14521771 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18266669 — Surrogate Endpoint (SUR): Blood pressure
Study 14534335 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 14534335 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 28580882 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28580882 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28580882 — Predictive Biomarker (PRD): Hormone receptor
Study 23618477 — Safety Biomarker (SAF): Reactive oxygen species
Study 18257780 — Surrogate Endpoint (SUR): Blood pressure
Study 3751746 — Surrogate Endpoint (SUR): Blood pressure
Study 3751746 — Surrogate Endpoint (SUR): Serum calcium
Study 31661198 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12087008 — Surrogate Endpoint (SUR): Blood pressure
Study 22570948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20026779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20026779 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18628266 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7572686 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28570161 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23561330 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 18235414 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28249384 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28249384 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23544333 — Surrogate Endpoint (SUR): Blood pressure
Study 18156031 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18156031 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9519948 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2804252 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31900673 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25002136 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21087898 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21087898 — Predictive Biomarker (PRD): Hormone receptor
Study 18281670 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9215817 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2447997 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17617790 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 15894537 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 11240954 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 3826206 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30102656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21232119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12562865 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 16254727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16254727 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20824664 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 20824664 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17223805 — Surrogate Endpoint (SUR): Blood pressure
Study 7831656 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7831656 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 3149240 — Surrogate Endpoint (SUR): Blood pressure
Study 21677633 — Surrogate Endpoint (SUR): Serum creatinine
Study 18270716 — Surrogate Endpoint (SUR): Blood pressure
Study 8768914 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8768914 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8768914 — Surrogate Endpoint (SUR): Serum creatinine
Study 6391131 — Surrogate Endpoint (SUR): Blood pressure
Study 17522615 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3161531 — Surrogate Endpoint (SUR): Blood pressure
Study 31403367 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 31438916 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31438916 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 31438916 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25436966 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 25436966 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11562748 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7945601 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30408255 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 24021217 — Predictive Biomarker (PRD): HTR1A mRNA
Genes: HTR1A; ADRB2RL1; ADRBRL1
Study 24021217 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 22009189 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 22009189 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 19390210 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19390210 — Surrogate Endpoint (SUR): Serum creatinine
Study 9506731 — Surrogate Endpoint (SUR): Bone mineral density
Study 9506731 — Surrogate Endpoint (SUR): Serum testosterone
Study 9506731 — Surrogate Endpoint (SUR): Serum calcium
Study 7511357 — Surrogate Endpoint (SUR): Blood pressure
Study 2893592 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 19699835 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2662099 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 16481637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8831919 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2454358 — Surrogate Endpoint (SUR): Blood pressure
Study 31281938 — Surrogate Endpoint (SUR): Bone mineral density
Study 21451004 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21451004 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16713143 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25452054 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 12717871 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7903211 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17321570 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17321570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17321570 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17321570 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15465230 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 3301079 — Surrogate Endpoint (SUR): Blood pressure
Study 3301079 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24374357 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 1280862 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21920461 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 29567761 — Safety Biomarker (SAF): Interleukin 1
Study 29567761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29567761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12846417 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 10976548 — Surrogate Endpoint (SUR): Blood pressure
Study 31062728 — Predictive Biomarker (PRD): MB mRNA
Genes: MB