TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28384521 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 28384521 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 17762645 — Surrogate Endpoint (SUR): Blood pressure
Study 8777381 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 29429253 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 22682949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30638154 — Surrogate Endpoint (SUR): Bone mineral density
Study 17084625 — Surrogate Endpoint (SUR): Serum testosterone
Study 16270721 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11801579 — Surrogate Endpoint (SUR): Serum creatinine
Study 23536720 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 19645607 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 15879360 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 31000896 — Surrogate Endpoint (SUR): Blood pressure
Study 25511549 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25511549 — Safety Biomarker (SAF): BDNF
Study 22517542 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11426017 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 14971524 — Surrogate Endpoint (SUR): Blood pressure
Study 8940228 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27307573 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 23102675 — Predictive Biomarker (PRD): BNC1 mRNA
Genes: BNC1; BNC
Study 15601521 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8116700 — Surrogate Endpoint (SUR): Blood pressure
Study 3056445 — Surrogate Endpoint (SUR): Blood pressure
Study 30928650 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 30928650 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 12444940 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24080858 — Surrogate Endpoint (SUR): Blood pressure
Study 12637206 — Surrogate Endpoint (SUR): Blood pressure
Study 6716067 — Predictive Biomarker (PRD): MEST mRNA
Genes: MEST; PEG1
Study 31785116 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28631453 — Surrogate Endpoint (SUR): Blood pressure
Study 18633677 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16933188 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10374374 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29703118 — Surrogate Endpoint (SUR): Blood pressure
Study 28212320 — Surrogate Endpoint (SUR): Blood pressure
Study 17432680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27765759 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1833800 — Surrogate Endpoint (SUR): Blood pressure
Study 29061598 — Surrogate Endpoint (SUR): Blood pressure
Study 25705007 — Surrogate Endpoint (SUR): Blood pressure
Study 24265036 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 24265036 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19938957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27671974 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23252716 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 21129895 — Predictive Biomarker (PRD): SQOR mRNA
Genes: SQOR; SQRDL; CGI-44
Study 3044503 — Surrogate Endpoint (SUR): Blood pressure
Study 3044503 — Surrogate Endpoint (SUR): Serum potassium
Study 11422660 — Surrogate Endpoint (SUR): Blood pressure
Study 7693420 — Predictive Biomarker (PRD): Hormone receptor
Study 22728230 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 16351359 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21068204 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 9422296 — Surrogate Endpoint (SUR): Blood pressure
Study 30876973 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 30876973 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 25176266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25176266 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25176266 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25176266 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23001240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16621194 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11236243 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1596703 — Surrogate Endpoint (SUR): Serum calcium
Study 1596703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30507032 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 29505522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29505522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17707537 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 17707537 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 10877311 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8623182 — Surrogate Endpoint (SUR): Serum creatinine
Study 8623182 — Surrogate Endpoint (SUR): Blood pressure
Study 19429669 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11081321 — Surrogate Endpoint (SUR): Blood pressure
Study 12843212 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 9715289 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study 18254272 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 31125470 — Surrogate Endpoint (SUR): Blood pressure
Study 26382732 — Surrogate Endpoint (SUR): Blood pressure
Study 23449533 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 8468720 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29529160 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29529160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12231524 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12231524 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 12231524 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30273493 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 20578224 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 18050627 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 12394555 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 6177963 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 6177963 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15687128 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 15687128 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11831544 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 31598495 — Surrogate Endpoint (SUR): Blood pressure
Study 17061994 — Surrogate Endpoint (SUR): Bone mineral density
Study 17061994 — Surrogate Endpoint (SUR): Serum creatinine
Study 11192132 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11192132 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11138827 — Surrogate Endpoint (SUR): Blood pressure
Study 11138827 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10769438 — Surrogate Endpoint (SUR): Bone mineral density
Study 17568589 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17083354 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 17083354 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 20495885 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 16700661 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 16700661 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 16700661 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16700661 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16185958 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 16185958 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 10872850 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29668399 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 17181618 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 30303628 — Surrogate Endpoint (SUR): Blood pressure
Study 19254210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19254210 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19254210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19254210 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15337403 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11772251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29071915 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29071915 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29071915 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29246678 — Surrogate Endpoint (SUR): Bone mineral density
Study 24772521 — Surrogate Endpoint (SUR): Blood pressure
Study 20981351 — Predictive Biomarker (PRD): RGS2 mRNA
Genes: RGS2; G0S8; GIG31
Study 20981351 — Surrogate Endpoint (SUR): Blood pressure
Study 11815318 — Safety Biomarker (SAF): MTHFR
Study 10078538 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 10078538 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 10078538 — Surrogate Endpoint (SUR): Blood pressure
Study 22051739 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18269772 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10077773 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 10077773 — Safety Biomarker (SAF): RFC1
Genes: A1; PO-GA; RFC140; MHCBFB
Study 30849106 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 28481241 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 28481241 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 28481241 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 28481241 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10960378 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25457355 — Surrogate Endpoint (SUR): Blood pressure
Study 17662509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11809427 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11809427 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27602993 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21602709 — Surrogate Endpoint (SUR): Blood pressure
Study 20021921 — Surrogate Endpoint (SUR): Blood pressure
Study 10669845 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29578176 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19680137 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19680137 — Surrogate Endpoint (SUR): Blood pressure
Study 17602982 — Surrogate Endpoint (SUR): Serum creatinine
Study 16283864 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7781496 — Surrogate Endpoint (SUR): Blood pressure
Study 21186075 — Surrogate Endpoint (SUR): Serum creatinine
Study 16412856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16412856 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16412856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16412856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11312479 — Surrogate Endpoint (SUR): Blood pressure
Study 11312479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26626430 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 16084689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10843175 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 31790890 — Surrogate Endpoint (SUR): Serum uric acid
Study 31790890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31790890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31790890 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 31790890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26719946 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 21143897 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15812256 — Surrogate Endpoint (SUR): Blood pressure
Study 9892402 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8897035 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 1676973 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 24827128 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 24827128 — Predictive Biomarker (PRD): Hormone receptor
Study 23185762 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 17922167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31354858 — Surrogate Endpoint (SUR): Serum creatinine
Study 22545736 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 30884986 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30884986 — Predictive Biomarker (PRD): Hormone receptor
Study 25155895 — Surrogate Endpoint (SUR): Blood pressure
Study 14697473 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23496212 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15864218 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20502133 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 9447610 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 9447610 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 11684628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11684628 — Safety Biomarker (SAF): Cytochrome c
Study 11684628 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 23654014 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 20512336 — Surrogate Endpoint (SUR): Bone mineral density
Study 17085009 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17085009 — Surrogate Endpoint (SUR): Blood pressure
Study 15692829 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15692829 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28489641 — Surrogate Endpoint (SUR): Blood pressure
Study 23152490 — Surrogate Endpoint (SUR): Blood pressure
Study 1725032 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1725032 — Surrogate Endpoint (SUR): Blood pressure
Study 24297848 — Predictive Biomarker (PRD): FNDC5 mRNA
Genes: FNDC5; FRCP2
Study 17906193 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17906193 — Surrogate Endpoint (SUR): Blood pressure
Study 28701493 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 2129513 — Surrogate Endpoint (SUR): Blood pressure
Study 28481883 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25858003 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 25858003 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 25858003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24108316 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 20730705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20730705 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 16112085 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 6351607 — Surrogate Endpoint (SUR): Serum creatinine
Study 29411727 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29411727 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 29411727 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12486342 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 10213254 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7606951 — Surrogate Endpoint (SUR): Forced vital capacity
Study 42487 — Surrogate Endpoint (SUR): Blood pressure
Study 17889127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17889127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17889127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15365919 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11515819 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26404200 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26404200 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25066921 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 11280847 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 25105662 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22238392 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 22238392 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 20304883 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8665534 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8665534 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 21994078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21994078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9883710 — Surrogate Endpoint (SUR): Blood pressure
Study 7976233 — Surrogate Endpoint (SUR): Blood pressure
Study 2968266 — Surrogate Endpoint (SUR): Bone mineral density
Study 22672255 — Surrogate Endpoint (SUR): Blood pressure
Study 20441516 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20441516 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20441516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10380161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7776711 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 28624914 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15800310 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 6786094 — Surrogate Endpoint (SUR): Serum testosterone
Study 31477085 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21184272 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8539159 — Surrogate Endpoint (SUR): Blood pressure
Study 31769181 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 17303799 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 14648339 — Surrogate Endpoint (SUR): Blood pressure
Study 9744148 — Surrogate Endpoint (SUR): Blood pressure
Study 25406966 — Surrogate Endpoint (SUR): Blood pressure
Study 25406966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25406966 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16943584 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 16943584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29408797 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29408797 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 29408797 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 29408797 — Predictive Biomarker (PRD): P2RY12 mRNA
Genes: P2RY12; HORK3
Study 26677666 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26677666 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 26677666 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 20206783 — Surrogate Endpoint (SUR): Blood pressure
Study 12706357 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 1535400 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1