TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31493163 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 31494135 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31498564 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31500552 — Surrogate Endpoint (SUR): Blood pressure
Study 31500586 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31500586 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 31500586 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 31502117 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 31502117 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 31502400 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31502400 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31502421 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 31504095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31504335 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31504342 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31504674 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31506080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 31506387 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study 31508518 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 31508518 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31508518 — Predictive Biomarker (PRD): RICTOR mRNA
Genes: RICTOR; KIAA1999
Study 31510768 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31510865 — Monitoring Biomarker (MOI): Cell-free DNA
Study 31510897 — Safety Biomarker (SAF): Interleukin 1
Study 31512728 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 31512728 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31512728 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 31513090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31513090 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31513270 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31513353 — Predictive Biomarker (PRD): STXBP2 mRNA
Genes: STXBP2; UNC18B
Study 31513353 — Safety Biomarker (SAF): Interleukin 1
Study 31514508 — Surrogate Endpoint (SUR): Blood pressure
Study 31514524 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 31515430 — Surrogate Endpoint (SUR): Blood pressure
Study 31516602 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 31516602 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 31518248 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 31518248 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 31519154 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31519694 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 31520559 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31520559 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31520559 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 31520559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31521128 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 31521574 — Surrogate Endpoint (SUR): Blood pressure
Study 31522619 — Surrogate Endpoint (SUR): Blood pressure
Study 31522983 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 31522983 — Predictive Biomarker (PRD): AIF1 mRNA
Genes: AIF1; G1; IBA1
Study 31522983 — Predictive Biomarker (PRD): HCG22 mRNA
Genes: HCG22; G2; PBMUCL2
Study 31522983 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 31523049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31523058 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31525774 — Surrogate Endpoint (SUR): Blood pressure
Study 31526121 — Predictive Biomarker (PRD): GRIN1 mRNA
Genes: GRIN1; NMDAR1
Study 31528838 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 31528838 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31528838 — Surrogate Endpoint (SUR): Blood pressure
Study 31529070 — Predictive Biomarker (PRD): CYP21A2 mRNA
Genes: CYP21A2; CYP21; CYP21B
Study 31529318 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31529318 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 31530565 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 31531823 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 31531991 — Surrogate Endpoint (SUR): Blood pressure
Study 31532522 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31533771 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 31533771 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 31533771 — Surrogate Endpoint (SUR): Bone mineral density
Study 31533814 — Predictive Biomarker (PRD): NCAM1 mRNA
Genes: NCAM1; NCAM
Study 31533818 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 31533818 — Predictive Biomarker (PRD): Microsatellite instability
Study 31534192 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31534773 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 31534782 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 31535207 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 31535207 — Predictive Biomarker (PRD): TM6SF2 mRNA
Genes: TM6SF2
Study 31536622 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31536622 — Surrogate Endpoint (SUR): Blood pressure
Study 31537486 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 31537486 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 31537486 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 31537565 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31538230 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31538230 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31538944 — Surrogate Endpoint (SUR): Blood pressure
Study 31539467 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 31539582 — Predictive Biomarker (PRD): EBP mRNA
Genes: EBP
Study 31539582 — Surrogate Endpoint (SUR): Blood pressure
Study 31539757 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 31539757 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study 31539757 — Predictive Biomarker (PRD): CHST3 mRNA
Genes: CHST3
Study 31539757 — Predictive Biomarker (PRD): SLC10A2 mRNA
Genes: SLC10A2; ASBT; ISBT; NTCP2
Study 31539757 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 31540306 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 31540339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31540745 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 31540966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 31541204 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31541381 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31541381 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 31541381 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31541381 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31541381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31541381 — Predictive Biomarker (PRD): Hormone receptor
Study 31542380 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 31542738 — Surrogate Endpoint (SUR): Blood pressure
Study 31544944 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 31544947 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 31544947 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 31548342 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31548621 — Surrogate Endpoint (SUR): Blood pressure
Study 31549001 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 31549155 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31551193 — Surrogate Endpoint (SUR): Blood pressure
Study 31551283 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 31551805 — Surrogate Endpoint (SUR): Blood pressure
Study 31552641 — Surrogate Endpoint (SUR): Blood pressure
Study 31553054 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31553205 — Predictive Biomarker (PRD): IVL mRNA
Genes: IVL
Study 31553487 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 31553487 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 31553501 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31553501 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31553501 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 31553639 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 31555382 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31555487 — Predictive Biomarker (PRD): Hormone receptor
Study 31555487 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31555522 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31555522 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 31555795 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31555795 — Surrogate Endpoint (SUR): Blood pressure
Study 31557279 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 31557423 — Surrogate Endpoint (SUR): Serum testosterone
Study 31558366 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31558424 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31558467 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31558467 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31558469 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 31558479 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31559169 — Predictive Biomarker (PRD): MARCKS mRNA
Genes: MARCKS; MACS; PRKCSL
Study 31559605 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 31560935 — Predictive Biomarker (PRD): CLK1 mRNA
Genes: CLK1; CLK
Study 31561395 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31561395 — Surrogate Endpoint (SUR): Serum creatinine
Study 31561395 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 31562145 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 31564440 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 31564556 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 31564849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31566105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31566148 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 31566148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31566438 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 31566438 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31566744 — Predictive Biomarker (PRD): PNN mRNA
Genes: PNN; DRS; MEMA
Study 31567524 — Surrogate Endpoint (SUR): Serum creatinine
Study 31567524 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 31567524 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31567634 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 31568271 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31570103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31570103 — Predictive Biomarker (PRD): SIRT6 mRNA
Genes: SIRT6; SIR2L6
Study 31570255 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 31570517 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 31570633 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31570634 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31570781 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31570822 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 31570822 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 31570822 — Predictive Biomarker (PRD): RAD51C mRNA
Genes: RAD51C; RAD51L2
Study 31570822 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study 31570822 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31570822 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 31573931 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 31573977 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31573980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31573980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31575939 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 31576684 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31578082 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 31578082 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 31578082 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31578311 — Predictive Biomarker (PRD): COL7A1 mRNA
Genes: COL7A1
Study 31578311 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 31578700 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 31579436 — Predictive Biomarker (PRD): GGN mRNA
Genes: GGN
Study 31579676 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 31581306 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31582553 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 31582673 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31583331 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31584094 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 31584094 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study 31584094 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31584094 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 31584094 — Predictive Biomarker (PRD): CD160 mRNA
Genes: CD160; BY55
Study 31584608 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31584608 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 31584608 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 31586493 — Surrogate Endpoint (SUR): Blood pressure
Study 31587882 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31588494 — Predictive Biomarker (PRD): INSR mRNA
Genes: INSR
Study 31588660 — Predictive Biomarker (PRD): ACSM1 mRNA
Genes: ACSM1; BUCS1; LAE; MACS1
Study 31588660 — Predictive Biomarker (PRD): AMACR mRNA
Genes: AMACR
Study 31588660 — Predictive Biomarker (PRD): CACNA1D mRNA
Genes: CACNA1D; CACH3; CACN4; CACNL1A2; CCHL1A2
Study 31588660 — Predictive Biomarker (PRD): DLX1 mRNA
Genes: DLX1
Study 31588660 — Predictive Biomarker (PRD): PLA2G7 mRNA
Genes: PLA2G7; PAFAH
Study 31588660 — Predictive Biomarker (PRD): RHOU mRNA
Genes: RHOU; ARHU; CDC42L1; G28K; WRCH1; SB128
Study 31588660 — Predictive Biomarker (PRD): SPINK1 mRNA
Genes: SPINK1; PSTI
Study 31588660 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 31588660 — Predictive Biomarker (PRD): TDRD1 mRNA
Genes: TDRD1
Study 31588864 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31593308 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 31593552 — Safety Biomarker (SAF): miR-16
Study 31593552 — Safety Biomarker (SAF): miR-15a
Genes: MIR15A
Study 31593563 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31596034 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 31598646 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31599928 — Safety Biomarker (SAF): NAT2
Genes: AAC2
Study 31599928 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 31599928 — Predictive Biomarker (PRD): SLC25A4 mRNA
Genes: SLC25A4; AAC1; ANT1
Study 31601692 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 31602320 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 31604781 — Surrogate Endpoint (SUR): Blood pressure
Study 31605106 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 31605514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31605514 — Safety Biomarker (SAF): BDNF
Study 31606419 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 31606880 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 31606971 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 31607443 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 31607443 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31609651 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 31611263 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 31612072 — Surrogate Endpoint (SUR): Blood pressure
Study 31612225 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31613328 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31615411 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31615432 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 31615432 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31615432 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31615452 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31615852 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31616309 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 31617211 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31617269 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 31617269 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 31617432 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 31617910 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 31617910 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 31617910 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31618131 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31618131 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31618131 — Predictive Biomarker (PRD): Hormone receptor
Study 31618131 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31618131 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 31618746 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 31618760 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 31619290 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31619468 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 31623522 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 31626649 — Surrogate Endpoint (SUR): Blood pressure
Study 31627210 — Predictive Biomarker (PRD): SCN9A mRNA
Genes: SCN9A; NENA
Study 31627210 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 31627746 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 31628118 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31628130 — Predictive Biomarker (PRD): PARK7 mRNA
Genes: PARK7
Study 31628130 — Predictive Biomarker (PRD): UFD1 mRNA
Genes: UFD1; UFD1L
Study 31628218 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 31628667 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31629403 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 31633999 — Predictive Biomarker (PRD): CLEC4D mRNA
Genes: CLEC4D; CLECSF8; MCL
Study 31639039 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31639692 — Predictive Biomarker (PRD): HEXIM2 mRNA
Genes: HEXIM2; L3
Study 31641582 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 31641633 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31641952 — Predictive Biomarker (PRD): CD79A mRNA
Genes: CD79A; IGA; MB1