TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8842574 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 8842574 — Surrogate Endpoint (SUR): Bone mineral density
Study 29752853 — Surrogate Endpoint (SUR): Blood pressure
Study 26350351 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16173330 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10631832 — Surrogate Endpoint (SUR): Blood pressure
Study 30307636 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 21285132 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30696977 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12455715 — Surrogate Endpoint (SUR): Blood pressure
Study 31400356 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 31400356 — Predictive Biomarker (PRD): MICB mRNA
Genes: MICB; PERB11.2
Study 26695758 — Surrogate Endpoint (SUR): Serum testosterone
Study 26695758 — Surrogate Endpoint (SUR): Bone mineral density
Study 20217117 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20217117 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20217117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18029463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25623753 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23134886 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18284461 — Surrogate Endpoint (SUR): Blood pressure
Study 7726425 — Surrogate Endpoint (SUR): Blood pressure
Study 117442 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10833890 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10833890 — Surrogate Endpoint (SUR): Blood pressure
Study 28651550 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 28651550 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 28651550 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 17259696 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17259696 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17259696 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11756055 — Surrogate Endpoint (SUR): Blood pressure
Study 7659386 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2473364 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 937876 — Surrogate Endpoint (SUR): Blood pressure
Study 28940709 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26037798 — Safety Biomarker (SAF): Derived neutrophil to lymphocyte
Study 26037798 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 26037798 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23569146 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 21320331 — Surrogate Endpoint (SUR): Blood pressure
Study 19165639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7965266 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29082595 — Surrogate Endpoint (SUR): Blood pressure
Study 27207917 — Safety Biomarker (SAF): Interleukin 1
Study 15655130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15655130 — Surrogate Endpoint (SUR): Blood pressure
Study 12805489 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 8606643 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 28145073 — Safety Biomarker (SAF): Hyaluronic acid
Study 2040035 — Surrogate Endpoint (SUR): Serum creatinine
Study 31069575 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 26739742 — Surrogate Endpoint (SUR): Blood pressure
Study 20179234 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10199760 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23787155 — Surrogate Endpoint (SUR): Serum creatinine
Study 23787155 — Surrogate Endpoint (SUR): Blood pressure
Study 14743544 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10877738 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15531675 — Safety Biomarker (SAF): Reactive oxygen species
Study 31335733 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 25845224 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20718625 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 10563709 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18713921 — Surrogate Endpoint (SUR): Blood pressure
Study 8117635 — Surrogate Endpoint (SUR): Blood pressure
Study 20448066 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 23901669 — Surrogate Endpoint (SUR): Blood pressure
Study 17565326 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 21348539 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 18509176 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18050628 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 6834370 — Surrogate Endpoint (SUR): Blood pressure
Study 31338545 — Surrogate Endpoint (SUR): Blood pressure
Study 30428891 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 364615 — Surrogate Endpoint (SUR): Serum creatinine
Study 29654563 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 17040215 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15124980 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21655762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21655762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17276952 — Surrogate Endpoint (SUR): Bone mineral density
Study 3298752 — Surrogate Endpoint (SUR): Blood pressure
Study 3298752 — Surrogate Endpoint (SUR): Serum creatinine
Study 29807307 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7848789 — Surrogate Endpoint (SUR): Blood pressure
Study 22968256 — Surrogate Endpoint (SUR): Bone mineral density
Study 22968256 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 21337878 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 17032661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28921935 — Predictive Biomarker (PRD): ADH1B mRNA
Genes: ADH1B; ADH2
Study 28921935 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 24841974 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24841974 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19004511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14514407 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 14514407 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 26511996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20519376 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20519376 — Surrogate Endpoint (SUR): Blood pressure
Study 1688495 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1688495 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 1688495 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 1688495 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31063156 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23510984 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 16750696 — Surrogate Endpoint (SUR): Blood pressure
Study 14508203 — Surrogate Endpoint (SUR): Blood pressure
Study 10913471 — Surrogate Endpoint (SUR): Blood pressure
Study 10913471 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26392095 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21816786 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21816786 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17023230 — Surrogate Endpoint (SUR): Blood pressure
Study 24137215 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16820589 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 16820589 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12759324 — Surrogate Endpoint (SUR): Bone mineral density
Study 25012288 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 16200817 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16200817 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 484501 — Surrogate Endpoint (SUR): Blood pressure
Study 19043151 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 31594719 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 31594719 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 31594719 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 25583256 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17546381 — Surrogate Endpoint (SUR): Blood pressure
Study 7995010 — Surrogate Endpoint (SUR): Blood pressure
Study 26682747 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 21575292 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 22571902 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25114907 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 15249317 — Surrogate Endpoint (SUR): Bone mineral density
Study 9723435 — Predictive Biomarker (PRD): TRERF1 mRNA
Genes: TRERF1; BCAR2; RAPA; TREP132
Study 23521115 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 10623692 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18487480 — Surrogate Endpoint (SUR): Blood pressure
Study 14768777 — Surrogate Endpoint (SUR): Blood pressure
Study 10697397 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 10697397 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21742514 — Surrogate Endpoint (SUR): Blood pressure
Study 21742514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10404421 — Surrogate Endpoint (SUR): Blood pressure
Study 29870591 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 29870591 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21194357 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15727187 — Surrogate Endpoint (SUR): Blood pressure
Study 29427024 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29427024 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29427024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25042737 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16332235 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 12149667 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12149667 — Surrogate Endpoint (SUR): Blood pressure
Study 11334905 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22855038 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12463311 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 12463311 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10514159 — Surrogate Endpoint (SUR): Blood pressure
Study 19095403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16990966 — Surrogate Endpoint (SUR): Blood pressure
Study 20124509 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 20124509 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 20124509 — Predictive Biomarker (PRD): MAFB mRNA
Genes: MAFB; KRML
Study 11737044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11737044 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8292465 — Surrogate Endpoint (SUR): Blood pressure
Study 22048714 — Surrogate Endpoint (SUR): Blood pressure
Study 9293972 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8297841 — Surrogate Endpoint (SUR): Blood pressure
Study 31997543 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 20626444 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15307543 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 10903236 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 10903236 — Surrogate Endpoint (SUR): Blood pressure
Study 10903236 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 8110072 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 31023258 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 16825088 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16825088 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30439793 — Surrogate Endpoint (SUR): Blood pressure
Study 27924398 — Surrogate Endpoint (SUR): Urinary oxalate
Study 21273893 — Surrogate Endpoint (SUR): Blood pressure
Study 21273893 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21273893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15257845 — Surrogate Endpoint (SUR): Blood pressure
Study 9504568 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26569545 — Surrogate Endpoint (SUR): Blood pressure
Study 15747253 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24610312 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22460142 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22460142 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 12420344 — Surrogate Endpoint (SUR): Blood pressure
Study 27852303 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27852303 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 27852303 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27852303 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8251721 — Predictive Biomarker (PRD): NXN mRNA
Genes: NXN; NRX
Study 17697209 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16123474 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16123474 — Surrogate Endpoint (SUR): Blood pressure
Study 11852667 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10431553 — Safety Biomarker (SAF): MTHFR
Study 30760581 — Safety Biomarker (SAF): APC
Genes: DP2; DP3; DP2.5; PPP1R46
Study 28381796 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 20718814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20718814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20718814 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17701048 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15970291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15970291 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15970291 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28634822 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26445565 — Surrogate Endpoint (SUR): Blood pressure
Study 15745291 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 3307390 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29150328 — Surrogate Endpoint (SUR): Serum testosterone
Study 16034044 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16034044 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 16034044 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16034044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16034044 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16034044 — Predictive Biomarker (PRD): Hormone receptor
Study 10065905 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 24037998 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22359979 — Surrogate Endpoint (SUR): Bone mineral density
Study 23380000 — Surrogate Endpoint (SUR): Serum sodium
Study 21725513 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 21725513 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15025747 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15025747 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 12423708 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24188161 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24188161 — Surrogate Endpoint (SUR): Blood pressure
Study 30277569 — Surrogate Endpoint (SUR): Serum testosterone
Study 20399327 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9695714 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9695714 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30408155 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 30408155 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 30408155 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 25238251 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19641984 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17134892 — Predictive Biomarker (PRD): Hormone receptor
Study 20704642 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 20704642 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 15490268 — Surrogate Endpoint (SUR): Bone mineral density
Study 15490268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28272402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17057135 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 28043438 — Surrogate Endpoint (SUR): Blood pressure
Study 25904747 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25904747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25904747 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18825772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10984077 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31620931 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30032191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30032191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27084589 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 14604567 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30368495 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 30368495 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 26857107 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22596166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22596166 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22596166 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22596166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22596166 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 20634720 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20634720 — Surrogate Endpoint (SUR): Blood pressure
Study 30909863 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 22749917 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 28177187 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28177187 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18444947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1889841 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1889841 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29417623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2