TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20308769 — Surrogate Endpoint (SUR): Serum calcium
Study 10212791 — Surrogate Endpoint (SUR): Pathological complete response
Study 26472752 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 22777298 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12687331 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 12687331 — Safety Biomarker (SAF): HLA-DQA1
Genes: CELIAC1
Study 3551602 — Surrogate Endpoint (SUR): Blood pressure
Study 3551602 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28060791 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 18056271 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31308305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22661243 — Surrogate Endpoint (SUR): Blood pressure
Study 22661243 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9854511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17488381 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 15114342 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 31138170 — Surrogate Endpoint (SUR): Blood pressure
Study 19351807 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19351807 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 12452237 — Surrogate Endpoint (SUR): Blood pressure
Study 10352377 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 29166732 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20108776 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20108776 — Monitoring Biomarker (MOI): HBV DNA
Study 9593111 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7530738 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7530738 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7530738 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 24212838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20934856 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19828122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17121895 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17121895 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17121895 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9305416 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7894212 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24778046 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17712126 — Surrogate Endpoint (SUR): Bone mineral density
Study 2536896 — Surrogate Endpoint (SUR): Blood pressure
Study 23381973 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 10710578 — Surrogate Endpoint (SUR): Blood pressure
Study 20216301 — Monitoring Biomarker (MOI): HBV DNA
Study 28669488 — Surrogate Endpoint (SUR): Blood pressure
Study 25368103 — Predictive Biomarker (PRD): MAPK8IP1 mRNA
Genes: MAPK8IP1; IB1; JIP1; PRKM8IP
Study 14691389 — Surrogate Endpoint (SUR): Blood pressure
Study 9884858 — Surrogate Endpoint (SUR): Blood pressure
Study 7926537 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30608175 — Predictive Biomarker (PRD): UCN3 mRNA
Genes: UCN3; SPC
Study 29729518 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17983800 — Monitoring Biomarker (MOI): HBV DNA
Study 31833168 — Monitoring Biomarker (MOI): Procalcitonin
Study 28747453 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24698216 — Surrogate Endpoint (SUR): Blood pressure
Study 18046976 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16530757 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28320978 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 16393262 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 16393262 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 2964253 — Surrogate Endpoint (SUR): Blood pressure
Study 25907985 — Surrogate Endpoint (SUR): Blood pressure
Study 23975134 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12535040 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9193433 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24947255 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15977464 — Surrogate Endpoint (SUR): Bone mineral density
Study 31213443 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 31213443 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27020487 — Surrogate Endpoint (SUR): Blood pressure
Study 7043753 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 12088814 — Surrogate Endpoint (SUR): Blood pressure
Study 31896529 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 23876062 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23876062 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23876062 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23876062 — Predictive Biomarker (PRD): Hormone receptor
Study 21142633 — Surrogate Endpoint (SUR): Blood pressure
Study 15635615 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 15635615 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 15635615 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31898531 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 28540483 — Surrogate Endpoint (SUR): Blood pressure
Study 23626006 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 16957058 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 25707402 — Surrogate Endpoint (SUR): Bone mineral density
Study 8424396 — Predictive Biomarker (PRD): Hormone receptor
Study 28762476 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 23752209 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 21038654 — Predictive Biomarker (PRD): SYNM mRNA
Genes: SYNM; DMN; KIAA0353; SYN
Study 12799884 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12799884 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 12799884 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 12799884 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 2646418 — Predictive Biomarker (PRD): PDP1 mRNA
Genes: PDP1; PDP; PPM2C
Study 27876449 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 26958015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23939631 — Surrogate Endpoint (SUR): Bone mineral density
Study 16165718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16165718 — Safety Biomarker (SAF): Reactive oxygen species
Study 12835216 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27736842 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27736842 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 22552038 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26582047 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26582047 — Safety Biomarker (SAF): BDNF
Study 10077172 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10077172 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 7745037 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 7745037 — Safety Biomarker (SAF): Reactive oxygen species
Study 2285619 — Surrogate Endpoint (SUR): Blood pressure
Study 21057805 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15539961 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8966143 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 8966143 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8966143 — Surrogate Endpoint (SUR): Blood pressure
Study 20631491 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18946667 — Surrogate Endpoint (SUR): Urinary oxalate
Study 17993874 — Surrogate Endpoint (SUR): Bone mineral density
Study 14760111 — Surrogate Endpoint (SUR): Serum triglycerides
Study 14760111 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29650336 — Surrogate Endpoint (SUR): Blood pressure
Study 25275251 — Surrogate Endpoint (SUR): Blood pressure
Study 22160628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22160628 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22160628 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19700470 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 19700470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19700470 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19700470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19700470 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19700470 — Surrogate Endpoint (SUR): Blood pressure
Study 17479947 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15543343 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 15543343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15543343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15543343 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15543343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1826891 — Surrogate Endpoint (SUR): Blood pressure
Study 1826891 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28546260 — Surrogate Endpoint (SUR): Serum creatinine
Study 26930181 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15002538 — Surrogate Endpoint (SUR): Serum calcium
Study 7510736 — Surrogate Endpoint (SUR): Blood pressure
Study 27345636 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15150679 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15150679 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11219635 — Surrogate Endpoint (SUR): Blood pressure
Study 354827 — Surrogate Endpoint (SUR): Blood pressure
Study 28760403 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25681236 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25681236 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23900457 — Monitoring Biomarker (MOI): HBV DNA
Study 22024610 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22024610 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 2142611 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24336820 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18035081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16129801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16129801 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10419117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7492381 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22133470 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22133470 — Surrogate Endpoint (SUR): Blood pressure
Study 8285627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8285627 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 8285627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8285627 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29745059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27791207 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 24919526 — Surrogate Endpoint (SUR): Blood pressure
Study 19665644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17417658 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15196111 — Safety Biomarker (SAF): Reactive oxygen species
Study 31960079 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 31960079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31960079 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 28177719 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 25116481 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 25116481 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 21569487 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17135035 — Surrogate Endpoint (SUR): Blood pressure
Study 25259540 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 21083596 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19137369 — Predictive Biomarker (PRD): GDA mRNA
Genes: GDA; KIAA1258
Study 17470824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11382858 — Predictive Biomarker (PRD): PRF1
Genes: PFP; P1; HPLH2
Study 7900630 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7900630 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 7900630 — Surrogate Endpoint (SUR): Blood pressure
Study 30034 — Surrogate Endpoint (SUR): Blood pressure
Study 30034 — Surrogate Endpoint (SUR): Serum potassium
Study 18206037 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 16004744 — Surrogate Endpoint (SUR): Blood pressure
Study 12402200 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 340158 — Surrogate Endpoint (SUR): Blood pressure
Study 20499427 — Surrogate Endpoint (SUR): Serum potassium
Study 11807965 — Surrogate Endpoint (SUR): Blood pressure
Study 23480783 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 23480783 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 16763547 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8306013 — Surrogate Endpoint (SUR): Blood pressure
Study 28486519 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18972768 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17006324 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27058396 — Surrogate Endpoint (SUR): Blood pressure
Study 20507732 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 20507732 — Monitoring Biomarker (MOI): HBV DNA
Study 11156963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31245901 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 29237497 — Safety Biomarker (SAF): Hyaluronic acid
Study 19382469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19382469 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9658721 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 9658721 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9658721 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9658721 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9658721 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 30596530 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 21377034 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10998012 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 10998012 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 23745947 — Predictive Biomarker (PRD): MSN mRNA
Genes: MSN
Study 16869455 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 30872380 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25946554 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 25523883 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9053465 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3585444 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24354476 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 11257563 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2872807 — Surrogate Endpoint (SUR): Blood pressure
Study 19214923 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15050493 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31133096 — Surrogate Endpoint (SUR): Blood pressure
Study 1446728 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3001664 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24281134 — Surrogate Endpoint (SUR): Blood pressure
Study 24281134 — Surrogate Endpoint (SUR): Serum sodium
Study 16080909 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 16080909 — Surrogate Endpoint (SUR): Blood pressure
Study 26762374 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 26762374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19925528 — Surrogate Endpoint (SUR): Blood pressure
Study 9270083 — Surrogate Endpoint (SUR): Blood pressure
Study 26003546 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26003546 — Safety Biomarker (SAF): BDNF
Study 23232039 — Predictive Biomarker (PRD): TNS4 mRNA
Genes: TNS4; CTEN; PP14434
Study 8364776 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 8364776 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20385988 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 20385988 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 18241260 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 18241260 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 23336578 — Surrogate Endpoint (SUR): Blood pressure
Study 2000823 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6655232 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6655232 — Surrogate Endpoint (SUR): Blood pressure
Study 31294473 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19845769 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 16868020 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31100514 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 20473893 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 11305513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11305513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11305513 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11305513 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 11305513 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 11305513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11305513 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11305513 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23855415 — Surrogate Endpoint (SUR): Blood pressure
Study 8109230 — Surrogate Endpoint (SUR): Blood pressure
Study 30848576 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 30848576 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 30848576 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 31546768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15878216 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 10634963 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23086295 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 23086295 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23086295 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31624333 — Pharmacodynamic Biomarker (PDY): Guanine nucleotide exchange factor C9orf72
Genes: C9orf72; DENND9; DENNL72