TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18949961 — Predictive Biomarker (PRD): EHF mRNA
Genes: EHF; ESE3; ESE3B; ESEJ
Study 20977501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15731987 — Predictive Biomarker (PRD): BNIP3L mRNA
Genes: BNIP3L; BNIP3A; BNIP3H; NIX
Study 23372145 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20801010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16177446 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10664826 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 10664826 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8863759 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8863759 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 3899672 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3899672 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 3899672 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3899672 — Surrogate Endpoint (SUR): Blood pressure
Study 22287757 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15468717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15468717 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31543378 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 28178209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28178209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28178209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28178209 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24847155 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15801953 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 2652176 — Surrogate Endpoint (SUR): Blood pressure
Study 25781235 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25781235 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25781235 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17100936 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 8090608 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8090608 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 23358966 — Surrogate Endpoint (SUR): Serum asparaginase
Study 8793703 — Surrogate Endpoint (SUR): Blood pressure
Study 8793703 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1465059 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15663123 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3585450 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 11421896 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 19751115 — Surrogate Endpoint (SUR): Blood pressure
Study 9284731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 29537647 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11576319 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11576319 — Surrogate Endpoint (SUR): Blood pressure
Study 3154680 — Surrogate Endpoint (SUR): Serum creatinine
Study 27665372 — Surrogate Endpoint (SUR): Blood pressure
Study 17879117 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 11039202 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 11039202 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 1603897 — Surrogate Endpoint (SUR): Blood pressure
Study 3932142 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31523892 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31523892 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16721398 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16721398 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11167171 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 8361220 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 30104327 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 17338717 — Surrogate Endpoint (SUR): Serum creatinine
Study 15284015 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15916853 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 15916853 — Safety Biomarker (SAF): Interleukin 1
Study 6787909 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29296854 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 31275597 — Surrogate Endpoint (SUR): Blood pressure
Study 10866044 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 3033182 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3033182 — Surrogate Endpoint (SUR): Blood pressure
Study 22147786 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10886233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8644400 — Surrogate Endpoint (SUR): Blood pressure
Study 24058089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24058089 — Surrogate Endpoint (SUR): Serum uric acid
Study 15540744 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 9286889 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23463656 — Surrogate Endpoint (SUR): Blood pressure
Study 8064580 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3330115 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27503659 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study 22094037 — Surrogate Endpoint (SUR): Blood pressure
Study 21606948 — Predictive Biomarker (PRD): CHRNB2 mRNA
Genes: CHRNB2
Study 16191054 — Surrogate Endpoint (SUR): Blood pressure
Study 10684018 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 26024743 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20105189 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 15972580 — Surrogate Endpoint (SUR): Bone mineral density
Study 8556225 — Surrogate Endpoint (SUR): Blood pressure
Study 30712247 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 30712247 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 30712247 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 21251805 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 21251805 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 19878793 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 17761981 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9138853 — Surrogate Endpoint (SUR): Blood pressure
Study 7681516 — Surrogate Endpoint (SUR): Blood pressure
Study 25311998 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20837352 — Surrogate Endpoint (SUR): Blood pressure
Study 11849868 — Surrogate Endpoint (SUR): Blood pressure
Study 31194885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31194885 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 29871185 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 24589090 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 17991638 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17991638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17991638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17991638 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17991638 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 17991638 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 17991638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16169320 — Predictive Biomarker (PRD): DUSP2 mRNA
Genes: DUSP2; PAC1
Study 2860268 — Surrogate Endpoint (SUR): Blood pressure
Study 31965906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31965906 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 31965906 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31965906 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27514766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18721577 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10597050 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 8739163 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17550348 — Surrogate Endpoint (SUR): Blood pressure
Study 1325513 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1325513 — Surrogate Endpoint (SUR): Blood pressure
Study 24644106 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 24644106 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 1407240 — Surrogate Endpoint (SUR): Serum calcium
Study 20186436 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20186436 — Surrogate Endpoint (SUR): Blood pressure
Study 27993433 — Surrogate Endpoint (SUR): Blood pressure
Study 10983907 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 10983907 — Predictive Biomarker (PRD): MGAT1 mRNA
Genes: MGAT1; GGNT1; GLCT1; GLYT1; MGAT
Study 10912884 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1718243 — Surrogate Endpoint (SUR): Blood pressure
Study 31296586 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20650012 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 17993030 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 15138667 — Surrogate Endpoint (SUR): Bone mineral density
Study 3063506 — Surrogate Endpoint (SUR): Blood pressure
Study 8395488 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24473249 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 15775780 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 15775780 — Surrogate Endpoint (SUR): Blood pressure
Study 1374201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27269942 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 22873700 — Surrogate Endpoint (SUR): Blood pressure
Study 18405704 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 16472719 — Surrogate Endpoint (SUR): Blood pressure
Study 10235107 — Surrogate Endpoint (SUR): Blood pressure
Study 30978434 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30978434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20156053 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14568851 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 10930151 — Safety Biomarker (SAF): IL-6 and IL-10
Study 31663569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21680653 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 18566109 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 8436747 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31468364 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 25222185 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25222185 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 25222185 — Surrogate Endpoint (SUR): Blood pressure
Study 27959613 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27959613 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21178939 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10459562 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2113567 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2113567 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 37871 — Surrogate Endpoint (SUR): Blood pressure
Study 27978548 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 27978548 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 27978548 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 27978548 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 27978548 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 27978548 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 27978548 — Predictive Biomarker (PRD): CASR mRNA
Genes: CASR; GPRC2A; PCAR1
Study 8139380 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8139380 — Surrogate Endpoint (SUR): Blood pressure
Study 29658856 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 22998533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22998533 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22998533 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21647656 — Surrogate Endpoint (SUR): Blood pressure
Study 18379534 — Surrogate Endpoint (SUR): Blood pressure
Study 16670153 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 1396829 — Safety Biomarker (SAF): 51Cr-EDTA
Study 1396829 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 4061896 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 4061896 — Surrogate Endpoint (SUR): Blood pressure
Study 30721637 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 29234038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29234038 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 29234038 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 29234038 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 29234038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29234038 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23625305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23625305 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23625305 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31296936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31296936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31296936 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 19548011 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 18689569 — Surrogate Endpoint (SUR): Blood pressure
Study 31125468 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 24988955 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20450503 — Surrogate Endpoint (SUR): Serum sodium
Study 12195113 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 12195113 — Surrogate Endpoint (SUR): Blood pressure
Study 1683148 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21071588 — Surrogate Endpoint (SUR): Blood pressure
Study 26858331 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 19817561 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 17455733 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26630416 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 26734916 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24583792 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 14679075 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 9053816 — Surrogate Endpoint (SUR): Blood pressure
Study 27905499 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27905499 — Safety Biomarker (SAF): BDNF
Study 19063834 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 19063834 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 19063834 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15736890 — Surrogate Endpoint (SUR): Probing pocket depth
Study 1670585 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29247068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29247068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19349153 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17447657 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 196518 — Surrogate Endpoint (SUR): Blood pressure
Study 28452989 — Safety Biomarker (SAF): Hyaluronic acid
Study 25740607 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 19014837 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8443808 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8443808 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 8443808 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8443808 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 18773156 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25332472 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20456336 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 20456336 — Surrogate Endpoint (SUR): Bone mineral density
Study 20456336 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 11889427 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 11889427 — Surrogate Endpoint (SUR): Bone mineral density
Study 10213466 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2141757 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2141757 — Surrogate Endpoint (SUR): Blood pressure
Study 19132974 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 19132974 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 19132974 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 19132974 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 14722203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3145297 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30661697 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30661697 — Surrogate Endpoint (SUR): Blood pressure
Study 30661697 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30661697 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23351822 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 16965429 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 15292315 — Surrogate Endpoint (SUR): Bone mineral density
Study 24596084 — Surrogate Endpoint (SUR): Serum creatinine
Study 14530982 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11412248 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11412248 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29483043 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20490354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20490354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20490354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12811362 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8472828 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30807234 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCNE1 mRNA
Genes: CCNE1; CCNE
Study 30807234 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 30807234 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study 30807234 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 30393030 — Predictive Biomarker (PRD): TNR mRNA
Genes: TNR
Study 30393030 — Predictive Biomarker (PRD): TKTL1 mRNA
Genes: TKTL1; TKR; TKT2
Study 12015188 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12015188 — Surrogate Endpoint (SUR): Blood pressure
Study 19125990 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 8478759 — Surrogate Endpoint (SUR): Blood pressure
Study 31700615 — Safety Biomarker (SAF): Interleukin 1
Study 23335852 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23335852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20358358 — Surrogate Endpoint (SUR): Bone mineral density
Study 11226087 — Surrogate Endpoint (SUR): Serum creatinine
Study 19657112 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG