TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7944879 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 29178685 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 21872708 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 9701188 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 9701188 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9701188 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9701188 — Surrogate Endpoint (SUR): Serum creatinine
Study 9701188 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28062311 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 28062311 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 16224198 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31077425 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 27904905 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2679864 — Surrogate Endpoint (SUR): Blood pressure
Study 22867815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22867815 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20624673 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19175374 — Surrogate Endpoint (SUR): Blood pressure
Study 2026743 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 28474112 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 16750996 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 15466644 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21880994 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 16784587 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 16784587 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8816209 — Surrogate Endpoint (SUR): Blood pressure
Study 23970305 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20137540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15232805 — Surrogate Endpoint (SUR): Blood pressure
Study 7903218 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 7903218 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 16595616 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8838506 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30191262 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 17196208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17196208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15948681 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 7985829 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29071755 — Surrogate Endpoint (SUR): Blood pressure
Study 26093363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28089149 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26122726 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 28502735 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 24662009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22483238 — Surrogate Endpoint (SUR): Blood pressure
Study 22483238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30365961 — Surrogate Endpoint (SUR): Serum creatinine
Study 26948161 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 24597608 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2196108 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2196108 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 100818 — Surrogate Endpoint (SUR): Blood pressure
Study 28962734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28962734 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 28962734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28962734 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28962734 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28962734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22174166 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11606013 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 27871086 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16042023 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 11952807 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 11952807 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 28662677 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 26295268 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 19833592 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19833592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3070826 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3070826 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16918762 — Predictive Biomarker (PRD): CBR1 mRNA
Genes: CBR1; CBR; CRN; SDR21C1
Study 20663568 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 19006791 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 26714784 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 26714784 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 26714784 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 26714784 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 23514036 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 18158618 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18158618 — Surrogate Endpoint (SUR): Blood pressure
Study 27297850 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25502755 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 25502755 — Predictive Biomarker (PRD): GPR61 mRNA
Genes: GPR61; BALGR; GPCR3
Study 25502755 — Predictive Biomarker (PRD): PRKCB mRNA
Genes: PRKCB; PKCB; PRKCB1
Study 22325157 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22325157 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 22325157 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10388499 — Surrogate Endpoint (SUR): Serum creatinine
Study 8905030 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24613294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24613294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19747047 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11783185 — Predictive Biomarker (PRD): RGN mRNA
Genes: RGN; SMP30
Study 31488289 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 21613745 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7535064 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 3555584 — Surrogate Endpoint (SUR): Blood pressure
Study 24286379 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 12952838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 12952838 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 23975885 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23425955 — Surrogate Endpoint (SUR): Blood pressure
Study 10638607 — Surrogate Endpoint (SUR): Pathological complete response
Study 1736753 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 20573795 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18632543 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 16891444 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16891444 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16891444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16891444 — Surrogate Endpoint (SUR): Blood pressure
Study 10834665 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 10834665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10834665 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21655743 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14511870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14511870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10510150 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8834127 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31033457 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 27069173 — Surrogate Endpoint (SUR): Serum creatinine
Study 22609644 — Surrogate Endpoint (SUR): Blood pressure
Study 11527124 — Surrogate Endpoint (SUR): Blood pressure
Study 6089555 — Surrogate Endpoint (SUR): Blood pressure
Study 6089555 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19941160 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16096715 — Surrogate Endpoint (SUR): Bone mineral density
Study 30803749 — Safety Biomarker (SAF): Interleukin 12
Study 30803749 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 30803749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26792024 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25172769 — Surrogate Endpoint (SUR): Blood pressure
Study 15576850 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 15576850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15576850 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26785711 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22784038 — Surrogate Endpoint (SUR): Bone mineral density
Study 28988746 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15242414 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study 11789085 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8039273 — Surrogate Endpoint (SUR): Blood pressure
Study 28425575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28425575 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 28425575 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11232942 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20519875 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 10607768 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 29194180 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 24024319 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24024319 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 24024319 — Surrogate Endpoint (SUR): Serum creatinine
Study 10781654 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22391074 — Predictive Biomarker (PRD): IFT122 mRNA
Genes: IFT122; SPG; WDR10; WDR140
Study 28601691 — Surrogate Endpoint (SUR): Blood pressure
Study 28601691 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17556718 — Surrogate Endpoint (SUR): Blood pressure
Study 17556718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7743368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7743368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2700362 — Surrogate Endpoint (SUR): Probing pocket depth
Study 792640 — Surrogate Endpoint (SUR): Blood pressure
Study 31694978 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8876706 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26810999 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22218376 — Safety Biomarker (SAF): Hyaluronic acid
Study 17380530 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15673841 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 30927229 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 28614910 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 22392565 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15148453 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 9478091 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 9478091 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 9478091 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7702797 — Surrogate Endpoint (SUR): Serum calcium
Study 7702797 — Surrogate Endpoint (SUR): Blood pressure
Study 3301155 — Surrogate Endpoint (SUR): Blood pressure
Study 28796316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26154185 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23657629 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 23657629 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 16879931 — Surrogate Endpoint (SUR): Blood pressure
Study 7923309 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7923309 — Surrogate Endpoint (SUR): Blood pressure
Study 3044508 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18419537 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16308351 — Safety Biomarker (SAF): Reactive oxygen species
Study 14515011 — Surrogate Endpoint (SUR): Serum testosterone
Study 29905973 — Surrogate Endpoint (SUR): Bone mineral density
Study 20055989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15699275 — Safety Biomarker (SAF): Reactive oxygen species
Study 4020121 — Surrogate Endpoint (SUR): Blood pressure
Study 25246739 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 25246739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29632995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24122814 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19346228 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8336989 — Safety Biomarker (SAF): RFC1
Genes: A1; PO-GA; RFC140; MHCBFB
Study 29095051 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 1622045 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31615480 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 25358874 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25358874 — Surrogate Endpoint (SUR): Serum creatinine
Study 19794973 — Surrogate Endpoint (SUR): Blood pressure
Study 15339577 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 28040073 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 15766369 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15766369 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7915149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16620590 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 14513920 — Surrogate Endpoint (SUR): Blood pressure
Study 21718959 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21718959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21718959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14656717 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 22939518 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22939518 — Surrogate Endpoint (SUR): Serum creatinine
Study 22939518 — Surrogate Endpoint (SUR): Blood pressure
Study 29061081 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29061081 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 29061081 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29061081 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 26013051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26013051 — Surrogate Endpoint (SUR): Blood pressure
Study 23163880 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 23163880 — Surrogate Endpoint (SUR): Blood pressure
Study 24370959 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18090696 — Surrogate Endpoint (SUR): Blood pressure
Study 12175374 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22383665 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 15833834 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9884249 — Surrogate Endpoint (SUR): Serum creatinine
Study 6498579 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6498579 — Surrogate Endpoint (SUR): Blood pressure
Study 26861957 — Safety Biomarker (SAF): Hyaluronic acid
Study 23566060 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23566060 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10947757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10947757 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9233735 — Safety Biomarker (SAF): Interleukin 1
Study 3305215 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26622051 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 26622051 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26622051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26622051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3122699 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 26254125 — Surrogate Endpoint (SUR): Blood pressure
Study 23163825 — Surrogate Endpoint (SUR): Blood pressure
Study 16679299 — Surrogate Endpoint (SUR): Blood pressure
Study 16679299 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16679299 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28985195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11450875 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29795368 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29795368 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21187254 — Surrogate Endpoint (SUR): Blood pressure
Study 16569462 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 1559192 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1559192 — Surrogate Endpoint (SUR): Blood pressure
Study 3926036 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2666019 — Surrogate Endpoint (SUR): Blood pressure
Study 140037 — Surrogate Endpoint (SUR): Blood pressure
Study 20694567 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20694567 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 15583076 — Surrogate Endpoint (SUR): Blood pressure
Study 7749822 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25966826 — Surrogate Endpoint (SUR): Blood pressure
Study 8072199 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28929861 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 28929861 — Predictive Biomarker (PRD): VCAN mRNA
Genes: VCAN; CSPG2
Study 28929861 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 28929861 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 21919691 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 30958358 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 17301637 — Surrogate Endpoint (SUR): Blood pressure
Study 11141144 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9321764 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 27801937 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25108305 — Predictive Biomarker (PRD): HDGFL2 mRNA
Genes: HDGFL2; HDGF2; HDGFRP2; HRP2; UNQ785/PRO1604
Study 20403303 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS