TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27428331 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 27430242 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 27430242 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27431598 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 27432917 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27433488 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 27433840 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 27435102 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 27435396 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27435882 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27436099 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27436749 — Surrogate Endpoint (SUR): Blood pressure
Study 27438353 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27444203 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 27444203 — Surrogate Endpoint (SUR): Blood pressure
Study 27445347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27453734 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27453775 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 27454930 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27454930 — Surrogate Endpoint (SUR): Pathological complete response
Study 27454930 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27455851 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27455851 — Predictive Biomarker (PRD): Hormone receptor
Study 27456841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27457375 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27457375 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27457375 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27457512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27459537 — Predictive Biomarker (PRD): CISD2 mRNA
Genes: CISD2; CDGSH2; ERIS; ZCD2
Study 27459537 — Safety Biomarker (SAF): Reactive oxygen species
Study 27460571 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 27461213 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27461255 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 27462120 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 27463414 — Surrogate Endpoint (SUR): Blood pressure
Study 27464202 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27464588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27464822 — Predictive Biomarker (PRD): Hormone receptor
Study 27464938 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 27464938 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27465021 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 27465105 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27467683 — Surrogate Endpoint (SUR): Probing pocket depth
Study 27468937 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27468938 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27471619 — Safety Biomarker (SAF): Reactive oxygen species
Study 27472156 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 27473473 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 27473815 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 27474763 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 27475524 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 27477483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27477483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27478115 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 27478897 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 27478897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27478897 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27479177 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 27479814 — Predictive Biomarker (PRD): CNGB3 mRNA
Genes: CNGB3
Study 27481622 — Predictive Biomarker (PRD): ZDHHC2 mRNA
Genes: ZDHHC2; REAM; REC; ZNF372
Study 27482888 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 27483008 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27483008 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 27483391 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 27485208 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27485208 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27485822 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27485822 — Surrogate Endpoint (SUR): Blood pressure
Study 27486205 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27486629 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27486660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27486660 — Surrogate Endpoint (SUR): Blood pressure
Study 27488552 — Surrogate Endpoint (SUR): Blood pressure
Study 27488898 — Predictive Biomarker (PRD): BMI1 mRNA
Genes: BMI1; PCGF4; RNF51
Study 27490919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27495056 — Surrogate Endpoint (SUR): Blood pressure
Study 27495287 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27495743 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 27495752 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27495955 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 27495955 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 27495955 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 27495955 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 27495955 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27496264 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27496946 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 27496946 — Surrogate Endpoint (SUR): Serum testosterone
Study 27499218 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 27501514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27501792 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 27502708 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 27503501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27503501 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 27504087 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 27504087 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27504087 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27504630 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 27504630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27507113 — Surrogate Endpoint (SUR): Serum sodium
Study 27507113 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27507156 — Predictive Biomarker (PRD): ALPL mRNA
Genes: ALPL
Study 27512970 — Surrogate Endpoint (SUR): Blood pressure
Study 27514750 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27515038 — Surrogate Endpoint (SUR): Blood pressure
Study 27515248 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 27515247 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27515247 — Surrogate Endpoint (SUR): Blood pressure
Study 27515250 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 27515250 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 27515308 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 27515308 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 27515308 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 27515308 — Predictive Biomarker (PRD): CD200 mRNA
Genes: CD200; MOX1; MOX2; My033
Study 27515308 — Predictive Biomarker (PRD): PDCD1LG2 mRNA
Genes: PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2
Study 27515308 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27515308 — Predictive Biomarker (PRD): CD248 mRNA
Genes: CD248; CD164L1; TEM1
Study 27515308 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 27519353 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27520560 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study 27520560 — Predictive Biomarker (PRD): HNF1B mRNA
Genes: HNF1B; TCF2
Study 27520560 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27520989 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27521361 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 27521361 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 27521361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27521362 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27522472 — Surrogate Endpoint (SUR): Blood pressure
Study 27524654 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 27525190 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 27525313 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27526372 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 27527001 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 27527831 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 27528460 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 27528460 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 27528724 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27531525 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 27531679 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 27532364 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27532364 — Monitoring Biomarker (MOI): Cell-free DNA
Study 27534260 — Surrogate Endpoint (SUR): Blood pressure
Study 27535544 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 27535663 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 27535748 — Surrogate Endpoint (SUR): Pathological complete response
Study 27536421 — Surrogate Endpoint (SUR): Blood pressure
Study 27536422 — Surrogate Endpoint (SUR): Bone mineral density
Study 27536431 — Surrogate Endpoint (SUR): Blood pressure
Study 27536437 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 27536437 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27536442 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 27536442 — Surrogate Endpoint (SUR): Blood pressure
Study 27536449 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 27536708 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27536708 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 27536938 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 27536938 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27537786 — Predictive Biomarker (PRD): Liver iron
Study 27538197 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 27538197 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27538433 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 27540019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27541373 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 27541380 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 27543526 — Surrogate Endpoint (SUR): Blood pressure
Study 27543601 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 27543601 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 27544054 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study 27544054 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27544832 — Surrogate Endpoint (SUR): Bone mineral density
Study 27547429 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 27547429 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27547429 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27549584 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 27549584 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 27551051 — Predictive Biomarker (PRD): Hormone receptor
Study 27551314 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 27551991 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27551991 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 27554105 — Predictive Biomarker (PRD): ZDHHC2 mRNA
Genes: ZDHHC2; REAM; REC; ZNF372
Study 27555917 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27555917 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 27556389 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 27556408 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27557643 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 27557643 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 27558635 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 27558635 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27561198 — Predictive Biomarker (PRD): SCARB1 mRNA
Genes: SCARB1; CD36L1; CLA1
Study 27561272 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27561272 — Surrogate Endpoint (SUR): Blood pressure
Study 27561722 — Predictive Biomarker (PRD): CRLF2 mRNA
Genes: CRLF2; CRL2; ILXR; TSLPR
Study 27561722 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 27565932 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27566701 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27566720 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 27570087 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 27570807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27571185 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 27573653 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27575984 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 27576310 — Surrogate Endpoint (SUR): Bone mineral density
Study 27576691 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27576691 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 27577191 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 27581055 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 27581469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27581469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27581518 — Predictive Biomarker (PRD): EPOR mRNA
Genes: EPOR
Study 27581518 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 27581518 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 27587380 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27588424 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 27590145 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study 27590665 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27595689 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 27595689 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27595689 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 27595689 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 27595689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27597981 — Monitoring Biomarker (MOI): Procalcitonin
Study 27597981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27599546 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 27599985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27599985 — Surrogate Endpoint (SUR): Blood pressure
Study 27600044 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 27600462 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 27601462 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27601554 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study 27601554 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 27602311 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 27602761 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27602761 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 27602761 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 27602761 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 27602761 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 27602761 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 27602761 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 27602967 — Safety Biomarker (SAF): Hyaluronic acid
Study 27603290 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27604771 — Predictive Biomarker (PRD): SLC7A5 mRNA
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study 27604771 — Predictive Biomarker (PRD): SLC38A2 mRNA
Genes: SLC38A2; ATA2; KIAA1382; SAT2; SNAT2
Study 27605156 — Predictive Biomarker (PRD): PLCG2 mRNA
Genes: PLCG2
Study 27605368 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27609188 — Surrogate Endpoint (SUR): Blood pressure
Study 27611192 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27611192 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27611967 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27612149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27612987 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27617637 — Predictive Biomarker (PRD): KLK3 mRNA
Genes: KLK3; APS
Study 27625344 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 27625344 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27625358 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 27627808 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 27627808 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 27627808 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 27627987 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27627987 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27627987 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27628523 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 27629052 — Predictive Biomarker (PRD): PLIN1 mRNA
Genes: PLIN1; PERI; PLIN
Study 27629486 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 27629486 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 27629486 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27629486 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 27629486 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 27629486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27630340 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 27631092 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 27631092 — Surrogate Endpoint (SUR): Bone mineral density
Study 27632289 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27632680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27633122 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27633393 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27633639 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 27634203 — Predictive Biomarker (PRD): JAK2
Genes: JTK10