TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10940797 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9028547 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20698844 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 11236238 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31810797 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24074484 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19619703 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 19619703 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19619703 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 19619703 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 19619703 — Predictive Biomarker (PRD): SCNN1A mRNA
Genes: SCNN1A; SCNN1
Study 19619703 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 19619703 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 8612379 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 6426754 — Surrogate Endpoint (SUR): Blood pressure
Study 20955571 — Predictive Biomarker (PRD): BCL2L10 mRNA
Genes: BCL2L10; BCL-B; BCLB; BOO; DIVA
Study 7846198 — Surrogate Endpoint (SUR): Blood pressure
Study 23296279 — Surrogate Endpoint (SUR): Blood pressure
Study 21484744 — Surrogate Endpoint (SUR): Bone mineral density
Study 11077130 — Surrogate Endpoint (SUR): Blood pressure
Study 26492167 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 21157390 — Surrogate Endpoint (SUR): Blood pressure
Study 19412140 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15066049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2667598 — Surrogate Endpoint (SUR): Blood pressure
Study 21183500 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 21183500 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21183500 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21183500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1974100 — Surrogate Endpoint (SUR): Blood pressure
Study 9842842 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 9842842 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9842842 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 9842842 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 412646 — Surrogate Endpoint (SUR): Blood pressure
Study 27159403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27159403 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 27159403 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 27159403 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 27159403 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27159403 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27159403 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12046348 — Safety Biomarker (SAF): RFC1
Genes: A1; PO-GA; RFC140; MHCBFB
Study 10036952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 6989067 — Surrogate Endpoint (SUR): Serum uric acid
Study 30709665 — Safety Biomarker (SAF): Glutamate dehydrogenase
Study 16770616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2949417 — Surrogate Endpoint (SUR): Serum testosterone
Study 29771169 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29771169 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29771169 — Safety Biomarker (SAF): Amphiregulin
Genes: AREG; AREGB; SDGF
Study 29771169 — Predictive Biomarker (PRD): FCGR2A mRNA
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 29771169 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 29771169 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 24986531 — Predictive Biomarker (PRD): GCG mRNA
Genes: GCG
Study 24986531 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15673388 — Safety Biomarker (SAF): KCNH2
Genes: Kv11.1; HERG; erg1
Study 3343914 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30579747 — Safety Biomarker (SAF): Hyaluronic acid
Study 3392892 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25213687 — Surrogate Endpoint (SUR): Blood pressure
Study 23462943 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 23462943 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22263599 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22263599 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17541495 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 11479480 — Predictive Biomarker (PRD): PSD4 mRNA
Genes: PSD4; EFA6B; TIC
Study 11479480 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11479480 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9828641 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21336679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21336679 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21336679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21336679 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 21336679 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21336679 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14585211 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 14585211 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 1574965 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 20499357 — Surrogate Endpoint (SUR): Bone mineral density
Study 73797 — Surrogate Endpoint (SUR): Serum creatinine
Study 23547804 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 23547804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12298188 — Surrogate Endpoint (SUR): Blood pressure
Study 28057030 — Surrogate Endpoint (SUR): Serum creatinine
Study 21409424 — Surrogate Endpoint (SUR): Blood pressure
Study 16357087 — Surrogate Endpoint (SUR): Blood pressure
Study 1682787 — Surrogate Endpoint (SUR): Blood pressure
Study 10690857 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29725806 — Safety Biomarker (SAF): Hyaluronic acid
Study 22237062 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 15815776 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22190137 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22190137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17221107 — Surrogate Endpoint (SUR): Blood pressure
Study 9001648 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 12046342 — Monitoring Biomarker (MOI): HBV DNA
Study 1977265 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 192685 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16980156 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 10588490 — Safety Biomarker (SAF): Interleukin 1
Study 1679390 — Surrogate Endpoint (SUR): Blood pressure
Study 22743239 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 22949107 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22949107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22949107 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22949107 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 22949107 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 22949107 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 21866654 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 19927544 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21255215 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21255215 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 21255215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16277094 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2696232 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2696232 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28985325 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24461582 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 2669567 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 1013666 — Surrogate Endpoint (SUR): Blood pressure
Study 1013666 — Surrogate Endpoint (SUR): Serum potassium
Study 12365864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12365864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7235354 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31364435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31364435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28219060 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16644338 — Surrogate Endpoint (SUR): Blood pressure
Study 14618464 — Surrogate Endpoint (SUR): Bone mineral density
Study 29700127 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17687648 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17687648 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 16861734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31010033 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 25740292 — Predictive Biomarker (PRD): ROCK1 mRNA
Genes: ROCK1
Study 25740292 — Predictive Biomarker (PRD): ROCK2 mRNA
Genes: ROCK2; KIAA0619
Study 31586376 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 24975522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24975522 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21320721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 19335072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11474638 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 7958670 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22768661 — Surrogate Endpoint (SUR): Bone mineral density
Study 10028936 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10028936 — Surrogate Endpoint (SUR): Blood pressure
Study 10829886 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 27487253 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 21204914 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 16688995 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12702115 — Surrogate Endpoint (SUR): Probing pocket depth
Study 3297810 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11032209 — Surrogate Endpoint (SUR): Serum sodium
Study 1553404 — Surrogate Endpoint (SUR): Blood pressure
Study 3883729 — Surrogate Endpoint (SUR): Blood pressure
Study 27424010 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 27424010 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 19149498 — Safety Biomarker (SAF): Reactive oxygen species
Study 15304592 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 9164913 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28827188 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 24615657 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22430688 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 18480691 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 12154114 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29258928 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 16382002 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16382002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16382002 — Surrogate Endpoint (SUR): Blood pressure
Study 16382002 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10781751 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19158317 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11893233 — Surrogate Endpoint (SUR): Blood pressure
Study 10442900 — Predictive Biomarker (PRD): ABCA4 mRNA
Genes: ABCA4; ABCR
Study 26188879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23388517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23388517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23388517 — Safety Biomarker (SAF): Interleukin 1
Study 23388517 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19681767 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19681767 — Monitoring Biomarker (MOI): Complement C4
Study 7831626 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 3207566 — Surrogate Endpoint (SUR): Blood pressure
Study 10534571 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 73856 — Surrogate Endpoint (SUR): Blood pressure
Study 17728549 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15139406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25846661 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25846661 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25846661 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 25846661 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 9446006 — Surrogate Endpoint (SUR): Serum creatinine
Study 31132111 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 25682769 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21917377 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 12960999 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12960999 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28497259 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 22248761 — Surrogate Endpoint (SUR): Blood pressure
Study 20658749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20658749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20658749 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20658749 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8853729 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1353367 — Surrogate Endpoint (SUR): Blood pressure
Study 24842917 — Surrogate Endpoint (SUR): Blood pressure
Study 16426255 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 3803414 — Surrogate Endpoint (SUR): Blood pressure
Study 30068784 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 3631784 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17934393 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17934393 — Surrogate Endpoint (SUR): Blood pressure
Study 28679495 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17578981 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17023713 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10658028 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1446868 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 23656766 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7789055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7789055 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 6357258 — Surrogate Endpoint (SUR): Blood pressure
Study 22974092 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22974092 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 22974092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8485825 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8485825 — Surrogate Endpoint (SUR): Blood pressure
Study 22275291 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 2899390 — Surrogate Endpoint (SUR): Blood pressure
Study 25142276 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25089169 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25089169 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2532921 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28870954 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 19168876 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19168876 — Surrogate Endpoint (SUR): Serum creatinine
Study 19168876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10233876 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22911624 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22911624 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 22911624 — Predictive Biomarker (PRD): CYP27A1 mRNA
Genes: CYP27A1; CYP27
Study 22911624 — Predictive Biomarker (PRD): ABCB4 mRNA
Genes: ABCB4; MDR3; PGY3
Study 22911624 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 22911624 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 3234467 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 24925584 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12534411 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8762348 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 1849810 — Surrogate Endpoint (SUR): Blood pressure
Study 31152605 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 21276644 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 17289744 — Surrogate Endpoint (SUR): Blood pressure
Study 2442788 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 23581697 — Surrogate Endpoint (SUR): Bone mineral density
Study 10900676 — Surrogate Endpoint (SUR): Blood pressure
Study 25154757 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 14514933 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10648310 — Surrogate Endpoint (SUR): Blood pressure
Study 8862501 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30487126 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30487126 — Monitoring Biomarker (MOI): Cell-free DNA
Study 30487126 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 29587324 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24760847 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24760847 — Safety Biomarker (SAF): BDNF
Study 22149876 — Predictive Biomarker (PRD): Hormone receptor
Study 15630048 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31595499 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30292541 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 27765690 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 20657311 — Surrogate Endpoint (SUR): Blood pressure
Study 16733169 — Surrogate Endpoint (SUR): Blood pressure