TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7067541 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27588078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27588078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27588078 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2830091 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1466208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16105981 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10808386 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 10808386 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27997703 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 21729116 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11374408 — Surrogate Endpoint (SUR): Serum creatinine
Study 27031035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17945482 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17945482 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 17945482 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17450677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17450677 — Safety Biomarker (SAF): Interleukin 1
Study 12755009 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30157824 — Predictive Biomarker (PRD): NGB mRNA
Genes: NGB
Study 26756747 — Surrogate Endpoint (SUR): Blood pressure
Study 25175099 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21335480 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21335480 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21335480 — Surrogate Endpoint (SUR): Blood pressure
Study 14667521 — Surrogate Endpoint (SUR): Serum creatinine
Study 25970339 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 16287954 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12221217 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 12221217 — Surrogate Endpoint (SUR): Bone mineral density
Study 2136970 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 28537062 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16478772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16478772 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12771610 — Surrogate Endpoint (SUR): Serum creatinine
Study 18606622 — Surrogate Endpoint (SUR): Blood pressure
Study 8249176 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29359677 — Surrogate Endpoint (SUR): Blood pressure
Study 28437237 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28437237 — Predictive Biomarker (PRD): DNER mRNA
Genes: DNER; BET; UNQ262/PRO299
Study 28437237 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 28437237 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 28437237 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 28437237 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 28437237 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 12 beta
Genes: IL12B; NKSF2
Study 28437237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11587406 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11587406 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8281530 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8281530 — Surrogate Endpoint (SUR): Blood pressure
Study 31978697 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16280696 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21752262 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 19770281 — Monitoring Biomarker (MOI): HBV DNA
Study 11149482 — Surrogate Endpoint (SUR): Bone mineral density
Study 31273511 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31273511 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31273511 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25658240 — Surrogate Endpoint (SUR): Blood pressure
Study 8806347 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31790749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 31790749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31790749 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30569640 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23030240 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 30040009 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30040009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28476039 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 19218826 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 26863234 — Surrogate Endpoint (SUR): Blood pressure
Study 20429696 — Surrogate Endpoint (SUR): Blood pressure
Study 11773086 — Monitoring Biomarker (MOI): HBV DNA
Study 367136 — Surrogate Endpoint (SUR): Blood pressure
Study 12771523 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 7930245 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1944608 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17541852 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 1346505 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30728457 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYH11 mRNA
Genes: MYH11; KIAA0866
Study 30728457 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 30728457 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 30728457 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 28407823 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 26188189 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23739574 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23739574 — Surrogate Endpoint (SUR): Blood pressure
Study 8094349 — Surrogate Endpoint (SUR): Blood pressure
Study 31051322 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20842070 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18316395 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26695388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20045497 — Predictive Biomarker (PRD): BMP2 mRNA
Genes: BMP2; BMP2A
Study 20045497 — Surrogate Endpoint (SUR): Bone mineral density
Study 15486003 — Surrogate Endpoint (SUR): Blood pressure
Study 12202963 — Surrogate Endpoint (SUR): Blood pressure
Study 1728438 — Surrogate Endpoint (SUR): Blood pressure
Study 1728438 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30988169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30988169 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29487995 — Surrogate Endpoint (SUR): Blood pressure
Study 20580752 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 20580752 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 10473803 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10473803 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 10473803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1725915 — Surrogate Endpoint (SUR): Blood pressure
Study 6789593 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29071382 — Surrogate Endpoint (SUR): Blood pressure
Study 20953817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29189568 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2355823 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 122406 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30939483 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 30939483 — Surrogate Endpoint (SUR): Serum creatinine
Study 26469104 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 26469104 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 22025157 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22025157 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 12045122 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 12045122 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10213433 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 10213433 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7789477 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 29133320 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 15495821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15495821 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3169110 — Surrogate Endpoint (SUR): Blood pressure
Study 29601367 — Safety Biomarker (SAF): BDNF
Study 26265125 — Surrogate Endpoint (SUR): Blood pressure
Study 23765639 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 23765639 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 23765639 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23765639 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21037437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21037437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19087497 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 11848258 — Surrogate Endpoint (SUR): Blood pressure
Study 17964871 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 17964871 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17964871 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15642561 — Surrogate Endpoint (SUR): Blood pressure
Study 15642561 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15642561 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15238420 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 15238420 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 28712090 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 20451040 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20451040 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 16787142 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 10385667 — Monitoring Biomarker (MOI): HBV DNA
Study 29508899 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 22789611 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 22789611 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 22789611 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 17898949 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17898949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15172082 — Surrogate Endpoint (SUR): Bone mineral density
Study 12224199 — Surrogate Endpoint (SUR): Blood pressure
Study 9704387 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10920582 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 10920582 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 31662003 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31662003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31662003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31662003 — Safety Biomarker (SAF): IL-6 and IL-10
Study 31662003 — Surrogate Endpoint (SUR): Serum calcium
Study 25069650 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8345812 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 2953318 — Surrogate Endpoint (SUR): Serum calcium
Study 27225610 — Surrogate Endpoint (SUR): Blood pressure
Study 25040793 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25040793 — Surrogate Endpoint (SUR): Blood pressure
Study 11039131 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 20448462 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20448462 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18702958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7980596 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 7980596 — Safety Biomarker (SAF): DRD2
Study 22240263 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12480510 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 14747232 — Surrogate Endpoint (SUR): Blood pressure
Study 25591054 — Surrogate Endpoint (SUR): Blood pressure
Study 16761891 — Surrogate Endpoint (SUR): Blood pressure
Study 9117220 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 23744329 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23744329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23744329 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17490568 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 7986708 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 31496653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31496653 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31496653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31496653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31496653 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17109337 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15009462 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15009462 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11571437 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 11571437 — Surrogate Endpoint (SUR): Blood pressure
Study 9669720 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9669720 — Surrogate Endpoint (SUR): Serum creatinine
Study 25166440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3046631 — Surrogate Endpoint (SUR): Blood pressure
Study 27166622 — Surrogate Endpoint (SUR): Blood pressure
Study 20868965 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20868965 — Surrogate Endpoint (SUR): Blood pressure
Study 1095159 — Surrogate Endpoint (SUR): Blood pressure
Study 25849627 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25849627 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21562066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21562066 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10866913 — Surrogate Endpoint (SUR): Blood pressure
Study 3511308 — Surrogate Endpoint (SUR): Blood pressure
Study 22398360 — Surrogate Endpoint (SUR): Blood pressure
Study 10483942 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30930429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24705337 — Predictive Biomarker (PRD): MEST mRNA
Genes: MEST; PEG1
Study 2826100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30509224 — Surrogate Endpoint (SUR): Blood pressure
Study 23999999 — Safety Biomarker (SAF): miR-22
Genes: MIR22
Study 22624833 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22624833 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 20592293 — Surrogate Endpoint (SUR): Serum testosterone
Study 12833187 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 8909662 — Surrogate Endpoint (SUR): Blood pressure
Study 24478323 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 12871893 — Surrogate Endpoint (SUR): Bone mineral density
Study 8793701 — Surrogate Endpoint (SUR): Blood pressure
Study 25486369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31543373 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 23812551 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19737620 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17403721 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17403721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17403721 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9398110 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9398110 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20588187 — Surrogate Endpoint (SUR): Blood pressure
Study 9236347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27904973 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23690996 — Predictive Biomarker (PRD): IRF7 mRNA
Genes: IRF7
Study 23690996 — Predictive Biomarker (PRD): IFIT1 mRNA
Genes: IFIT1; G10P1; IFI56; IFNAI1; ISG56
Study 23690996 — Predictive Biomarker (PRD): IFIT5 mRNA
Genes: IFIT5; ISG58; RI58
Study 23690996 — Predictive Biomarker (PRD): OASL mRNA
Genes: OASL; TRIP14
Study 23690996 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study 23690996 — Predictive Biomarker (PRD): PSMB9 mRNA
Genes: PSMB9; LMP2; PSMB6i; RING12
Study 23690996 — Predictive Biomarker (PRD): HERC5 mRNA
Genes: HERC5; CEB1; CEBP1
Study 23690996 — Predictive Biomarker (PRD): CCR1 mRNA
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 23690996 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 23690996 — Predictive Biomarker (PRD): MS4A4A mRNA
Genes: MS4A4A; 4SPAN1; CD20L1; MS4A4; HDCME31P
Study 23690996 — Predictive Biomarker (PRD): XAF1 mRNA
Genes: XAF1; BIRC4BP; XIAPAF1
Study 12925845 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9411502 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28770549 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 31335937 — Surrogate Endpoint (SUR): Blood pressure
Study 22271474 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15226321 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 3207437 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10513041 — Surrogate Endpoint (SUR): Blood pressure
Study 8558158 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 24364085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11170060 — Monitoring Biomarker (MOI): HBV DNA
Study 23275352 — Predictive Biomarker (PRD): AZGP1 mRNA
Genes: AZGP1; ZAG; ZNGP1
Study 21986347 — Surrogate Endpoint (SUR): Blood pressure
Study 30688550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12741429 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11345288 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11345288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11345288 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7526102 — Surrogate Endpoint (SUR): Blood pressure
Study 3299004 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 3299004 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28917688 — Predictive Biomarker (PRD): SHD mRNA
Genes: SHD
Study 28917688 — Surrogate Endpoint (SUR): Blood pressure
Study 23713213 — Predictive Biomarker (PRD): HR mRNA
Genes: HR