TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16796928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11126231 — Surrogate Endpoint (SUR): Blood pressure
Study 12019280 — Surrogate Endpoint (SUR): Blood pressure
Study 30321764 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 30321764 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21297503 — Surrogate Endpoint (SUR): Blood pressure
Study 26961111 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26961111 — Surrogate Endpoint (SUR): Blood pressure
Study 21110842 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 18266402 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14534336 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 11264156 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29093280 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23817470 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12974197 — Surrogate Endpoint (SUR): Serum creatinine
Study 8626361 — Surrogate Endpoint (SUR): Blood pressure
Study 24130680 — Surrogate Endpoint (SUR): Blood pressure
Study 15797582 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 11944613 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30312118 — Surrogate Endpoint (SUR): Bone mineral density
Study 28736139 — Monitoring Biomarker (MOI): HBV DNA
Study 26953856 — Surrogate Endpoint (SUR): Blood pressure
Study 24834811 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25998500 — Surrogate Endpoint (SUR): Serum uric acid
Study 25998500 — Surrogate Endpoint (SUR): Blood pressure
Study 25998500 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25998500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23003917 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18716365 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 18716365 — Surrogate Endpoint (SUR): Blood pressure
Study 18716365 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28259476 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 28259476 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 28259476 — Monitoring Biomarker (MOI): Cell-free DNA
Study 15252161 — Surrogate Endpoint (SUR): Serum potassium
Study 24509430 — Predictive Biomarker (PRD): HCN4 mRNA
Genes: HCN4
Study 24509430 — Surrogate Endpoint (SUR): Blood pressure
Study 1428567 — Surrogate Endpoint (SUR): Blood pressure
Study 6776576 — Surrogate Endpoint (SUR): Blood pressure
Study 28114607 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 17069818 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 10194425 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10194425 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2089047 — Surrogate Endpoint (SUR): Blood pressure
Study 10818327 — Surrogate Endpoint (SUR): Blood pressure
Study 31918039 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 29759717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29759717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27384560 — Safety Biomarker (SAF): Hyaluronic acid
Study 18248809 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 2127261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2127261 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 29931719 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 22551976 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 22551976 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22551976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22551976 — Safety Biomarker (SAF): Reactive oxygen species
Study 20127656 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 11914742 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10446816 — Surrogate Endpoint (SUR): Serum potassium
Study 7844602 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 454092 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 454092 — Predictive Biomarker (PRD): MAOB mRNA
Genes: MAOB
Study 30016404 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 30061523 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 30061523 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 27568389 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27568389 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 20494239 — Surrogate Endpoint (SUR): Blood pressure
Study 20494239 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16096858 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 7495925 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 29317191 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29317191 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22975755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22975755 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22975755 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 22975755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22975755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16357874 — Surrogate Endpoint (SUR): Blood pressure
Study 31489589 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 26820395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26820395 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7768080 — Surrogate Endpoint (SUR): Blood pressure
Study 30786924 — Predictive Biomarker (PRD): TYRP1 mRNA
Genes: TYRP1; CAS2; TYRP; TYRRP
Study 30786924 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 30786924 — Predictive Biomarker (PRD): RTL1 mRNA
Genes: RTL1; MAR1; MART1; PEG11
Study 30786924 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 26738952 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24452238 — Surrogate Endpoint (SUR): Blood pressure
Study 24452238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11922254 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 25707524 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19923383 — Surrogate Endpoint (SUR): Blood pressure
Study 8418171 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12757988 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12757988 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12757988 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12757988 — Surrogate Endpoint (SUR): Blood pressure
Study 10490724 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23169470 — Surrogate Endpoint (SUR): Blood pressure
Study 6391137 — Surrogate Endpoint (SUR): Blood pressure
Study 12877899 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9197878 — Surrogate Endpoint (SUR): Bone mineral density
Study 1416323 — Surrogate Endpoint (SUR): Serum sodium
Study 29747310 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20142756 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 6092410 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24692847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16206346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16206346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16206346 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 16206346 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 2248757 — Surrogate Endpoint (SUR): Blood pressure
Study 19255287 — Monitoring Biomarker (MOI): Procalcitonin
Study 9740088 — Predictive Biomarker (PRD): TRO mRNA
Genes: TRO; KIAA1114; MAGED3
Study 9740088 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30367952 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 14687223 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 14687223 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 14687223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11757712 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 3665190 — Surrogate Endpoint (SUR): Blood pressure
Study 24662224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24662224 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22343272 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 20067513 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18753727 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 18753727 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3532749 — Surrogate Endpoint (SUR): Blood pressure
Study 26281475 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 22085427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12522373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27407053 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24703531 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24703531 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 2880810 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 2880810 — Surrogate Endpoint (SUR): Blood pressure
Study 30286851 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26813970 — Predictive Biomarker (PRD): SFTPB mRNA
Genes: SFTPB; SFTP3
Study 24777164 — Surrogate Endpoint (SUR): Blood pressure
Study 16418753 — Surrogate Endpoint (SUR): Blood pressure
Study 29031239 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 17375118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17375118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1578910 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 1578910 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21816692 — Surrogate Endpoint (SUR): Blood pressure
Study 11710662 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9213203 — Surrogate Endpoint (SUR): Blood pressure
Study 10779310 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3315914 — Surrogate Endpoint (SUR): Blood pressure
Study 23690424 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23690424 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 3282893 — Surrogate Endpoint (SUR): Blood pressure
Study 31356537 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31356537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29374995 — Surrogate Endpoint (SUR): Blood pressure
Study 20665501 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 17602073 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2117680 — Surrogate Endpoint (SUR): Blood pressure
Study 22000773 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15640898 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10099041 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 31020550 — Surrogate Endpoint (SUR): Blood pressure
Study 10720508 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3091164 — Surrogate Endpoint (SUR): Blood pressure
Study 18636265 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 6696358 — Surrogate Endpoint (SUR): Serum testosterone
Study 10902750 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22951521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22951521 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 22951521 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22951521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22951521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22951521 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15671558 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 15671558 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6366125 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15498043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23999456 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11205494 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 8955577 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8955577 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 8955577 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 27943008 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 16542201 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29659956 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29659956 — Surrogate Endpoint (SUR): Blood pressure
Study 16815189 — Surrogate Endpoint (SUR): Blood pressure
Study 10882586 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 10882586 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 10882586 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8672377 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 8672377 — Predictive Biomarker (PRD): PLXNB1 mRNA
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 20492840 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30583748 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 16214443 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16214443 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10544903 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10544903 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 6778189 — Surrogate Endpoint (SUR): Blood pressure
Study 23647888 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23647888 — Predictive Biomarker (PRD): TXNRD1 mRNA
Genes: TXNRD1; GRIM12; KDRF
Study 19494551 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 15598479 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11306524 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11306524 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29032139 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22421926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18458640 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 10723115 — Surrogate Endpoint (SUR): Blood pressure
Study 10723115 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6274580 — Surrogate Endpoint (SUR): Blood pressure
Study 25145522 — Surrogate Endpoint (SUR): Blood pressure
Study 17765649 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17765649 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 26611718 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16770244 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 11775133 — Surrogate Endpoint (SUR): Blood pressure
Study 12551672 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 38180 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31202506 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17921131 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17921131 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 17921131 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9762674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9762674 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9762674 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16451856 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15136379 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15136379 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15136379 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 3326926 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29276990 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 26552742 — Surrogate Endpoint (SUR): Blood pressure
Study 21084969 — Surrogate Endpoint (SUR): Blood pressure
Study 19177029 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 19177029 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23401447 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18554591 — Safety Biomarker (SAF): Reactive oxygen species
Study 30365009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23429495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21420063 — Surrogate Endpoint (SUR): Serum creatinine
Study 2817186 — Surrogate Endpoint (SUR): Blood pressure
Study 31004853 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26250495 — Predictive Biomarker (PRD): WBP2NL mRNA
Genes: WBP2NL; PAWP
Study 14512806 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16645173 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14652358 — Surrogate Endpoint (SUR): Blood pressure
Study 24944128 — Surrogate Endpoint (SUR): Blood pressure
Study 15914548 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27548106 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 27548106 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10026394 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 7473528 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22380743 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 7678684 — Surrogate Endpoint (SUR): Blood pressure
Study 2889081 — Monitoring Biomarker (MOI): HBV DNA
Study 25579466 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 25579466 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 8811478 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29532981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29532981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10356941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21123766 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study 21123766 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 21123766 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 21123766 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 21123766 — Predictive Biomarker (PRD): ABCG8 mRNA
Genes: ABCG8
Study 19652945 — Surrogate Endpoint (SUR): Serum creatinine
Study 24199687 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 24199687 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21330809 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18712029 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 14513648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 10371363 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 10371363 — Surrogate Endpoint (SUR): Blood pressure
Study 30712804 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30712804 — Predictive Biomarker (PRD): Hormone receptor
Study 17522509 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 15241630 — Predictive Biomarker (PRD): NMI mRNA
Genes: NMI
Study 18668226 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE