TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23526069 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23526069 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9093237 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21925260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21925260 — Safety Biomarker (SAF): IL-6 and IL-10
Study 2649308 — Surrogate Endpoint (SUR): Blood pressure
Study 30923873 — Predictive Biomarker (PRD): BMAL1 mRNA
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 30923873 — Predictive Biomarker (PRD): PER2 mRNA
Genes: PER2; KIAA0347
Study 30923873 — Predictive Biomarker (PRD): CRY1 mRNA
Genes: CRY1; PHLL1
Study 30923873 — Predictive Biomarker (PRD): NR1D1 mRNA
Genes: NR1D1; EAR1; HREV; THRAL
Study 28873749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25936724 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23730991 — Surrogate Endpoint (SUR): Blood pressure
Study 15010556 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23298524 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study 12558462 — Surrogate Endpoint (SUR): Serum creatinine
Study 28228428 — Surrogate Endpoint (SUR): Blood pressure
Study 9105569 — Surrogate Endpoint (SUR): Blood pressure
Study 2294135 — Surrogate Endpoint (SUR): Serum calcium
Study 2294135 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2294135 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9822508 — Surrogate Endpoint (SUR): Blood pressure
Study 535777 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 22434736 — Surrogate Endpoint (SUR): Blood pressure
Study 22434736 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9620508 — Surrogate Endpoint (SUR): Blood pressure
Study 22699287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16115125 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 16115125 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study 16115125 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 28622623 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 28622623 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 28622623 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21894446 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 19581537 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 17121785 — Surrogate Endpoint (SUR): Blood pressure
Study 11996957 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11996957 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9583841 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7684524 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2879832 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22096040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30565412 — Surrogate Endpoint (SUR): Blood pressure
Study 2179284 — Surrogate Endpoint (SUR): Blood pressure
Study 23789288 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30148969 — Surrogate Endpoint (SUR): Blood pressure
Study 27401638 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12700955 — Surrogate Endpoint (SUR): Blood pressure
Study 29327055 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25265658 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 17167111 — Surrogate Endpoint (SUR): Serum creatinine
Study 22773302 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20127139 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 8187320 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 8187320 — Surrogate Endpoint (SUR): Serum calcium
Study 8187320 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31969368 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23500314 — Surrogate Endpoint (SUR): Serum creatinine
Study 16412796 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29351490 — Surrogate Endpoint (SUR): Blood pressure
Study 12145076 — Surrogate Endpoint (SUR): Blood pressure
Study 18513639 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 12521654 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12521654 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 12521654 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 8733685 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24748637 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 11005561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11005561 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30202185 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 10579613 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 8729530 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 24289920 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 22344966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22344966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22344966 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15970067 — Surrogate Endpoint (SUR): Blood pressure
Study 15970067 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15970067 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31803504 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31803504 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24195949 — Predictive Biomarker (PRD): SH2D1A mRNA
Genes: SH2D1A; DSHP; SAP
Study 8095119 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 2876741 — Surrogate Endpoint (SUR): Blood pressure
Study 24898426 — Surrogate Endpoint (SUR): Bone mineral density
Study 18690349 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15978306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15978306 — Surrogate Endpoint (SUR): Blood pressure
Study 15978306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15978306 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10500023 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22809163 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22276821 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22276821 — Surrogate Endpoint (SUR): Pathological complete response
Study 22276821 — Predictive Biomarker (PRD): Hormone receptor
Study 20858863 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20858863 — Surrogate Endpoint (SUR): Blood pressure
Study 15848695 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10206381 — Surrogate Endpoint (SUR): Blood pressure
Study 10206381 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10206381 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10206381 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30457436 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 19149760 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15202617 — Surrogate Endpoint (SUR): Blood pressure
Study 25638740 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 25638740 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25638740 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 19138934 — Predictive Biomarker (PRD): FHIT mRNA
Genes: FHIT
Study 1415419 — Surrogate Endpoint (SUR): Blood pressure
Study 31917424 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23657091 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 23657091 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 23657091 — Predictive Biomarker (PRD): MAST1 mRNA
Genes: MAST1; KIAA0973; SAST
Study 23657091 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 19708562 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 19708562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8918276 — Surrogate Endpoint (SUR): Blood pressure
Study 10378920 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25831651 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16194048 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12022239 — Surrogate Endpoint (SUR): Blood pressure
Study 30346226 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27797925 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 27797925 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27797925 — Surrogate Endpoint (SUR): Serum creatinine
Study 26110815 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 21294797 — Surrogate Endpoint (SUR): Blood pressure
Study 9138682 — Surrogate Endpoint (SUR): Blood pressure
Study 29730458 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 24372884 — Predictive Biomarker (PRD): CELF4 mRNA
Genes: CELF4; BRUNOL4
Study 22289695 — Surrogate Endpoint (SUR): Blood pressure
Study 9433680 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 9433680 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9433680 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22075171 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20088993 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8888089 — Surrogate Endpoint (SUR): Blood pressure
Study 3125575 — Surrogate Endpoint (SUR): Blood pressure
Study 29525494 — Surrogate Endpoint (SUR): Blood pressure
Study 27487342 — Surrogate Endpoint (SUR): Serum calcium
Study 20569506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30514803 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 30514803 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 25418218 — Surrogate Endpoint (SUR): Serum creatinine
Study 15293053 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2913779 — Surrogate Endpoint (SUR): Blood pressure
Study 2913779 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26350273 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26350273 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8455310 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8455310 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20194448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1624634 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29372470 — Surrogate Endpoint (SUR): Serum uric acid
Study 19227901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15895898 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12195121 — Surrogate Endpoint (SUR): Blood pressure
Study 11233145 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21820539 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17077730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9661740 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 31694237 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31694237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31694237 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 31694237 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31694237 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31694237 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26057939 — Surrogate Endpoint (SUR): Blood pressure
Study 23937271 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 21803422 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19781210 — Surrogate Endpoint (SUR): Serum creatinine
Study 19781210 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16487269 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 16487269 — Predictive Biomarker (PRD): GNB3
Study 29607480 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study 29607480 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 23556337 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23556337 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 23556337 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 23556337 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 23556337 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 8498732 — Surrogate Endpoint (SUR): Blood pressure
Study 30289174 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30289174 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 20420639 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 3814226 — Surrogate Endpoint (SUR): Blood pressure
Study 27022112 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27022112 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25233931 — Predictive Biomarker (PRD): UGT2B10 mRNA
Genes: UGT2B10
Study 17885721 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 9094063 — Surrogate Endpoint (SUR): Blood pressure
Study 19210135 — Predictive Biomarker (PRD): SYNE2 mRNA
Genes: SYNE2; KIAA1011; NUA
Study 15548759 — Safety Biomarker (SAF): MTHFR
Study 9760346 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8091168 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 2968363 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 30013785 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 29233783 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24202240 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10633478 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 31950855 — Surrogate Endpoint (SUR): Blood pressure
Study 11451210 — Surrogate Endpoint (SUR): Blood pressure
Study 1071671 — Surrogate Endpoint (SUR): Blood pressure
Study 31121015 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21669162 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21669162 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 21669162 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1416161 — Surrogate Endpoint (SUR): Blood pressure
Study 10468701 — Surrogate Endpoint (SUR): Serum testosterone
Study 10468701 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 2105070 — Surrogate Endpoint (SUR): Blood pressure
Study 26858279 — Surrogate Endpoint (SUR): Blood pressure
Study 22843789 — Predictive Biomarker (PRD): FGD4 mRNA
Genes: FGD4; FRABP; ZFYVE6
Study 22843789 — Predictive Biomarker (PRD): EPHA5 mRNA
Genes: EPHA5; BSK; EHK1; HEK7; TYRO4
Study 17545373 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 16287454 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12221405 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 31443727 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 19809205 — Surrogate Endpoint (SUR): Blood pressure
Study 9211021 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31221679 — Surrogate Endpoint (SUR): Serum creatinine
Study 23328090 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12742982 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 10823263 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10823263 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8888744 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23700932 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11876691 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 6383111 — Surrogate Endpoint (SUR): Blood pressure
Study 23228988 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 9384464 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9384464 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9384464 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 9384464 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9384464 — Surrogate Endpoint (SUR): Blood pressure
Study 1314337 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29652778 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 25064627 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 29636004 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29636004 — Surrogate Endpoint (SUR): Blood pressure
Study 28543352 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 15705991 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30032394 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 27294349 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19081190 — Predictive Biomarker (PRD): GCH1 mRNA
Genes: GCH1; DYT5; GCH
Study 15242361 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 31748427 — Surrogate Endpoint (SUR): Serum uric acid
Study 31748427 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 31748427 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31748427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31748427 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31748427 — Surrogate Endpoint (SUR): Serum creatinine
Study 20877300 — Predictive Biomarker (PRD): GDA mRNA
Genes: GDA; KIAA1258
Study 20877300 — Predictive Biomarker (PRD): KCNIP4 mRNA
Genes: KCNIP4; CALP; KCHIP4
Study 20877300 — Predictive Biomarker (PRD): APOO mRNA
Genes: APOO; FAM121B; MIC23; MIC26; My025; UNQ1866/PRO4302
Study 20877300 — Predictive Biomarker (PRD): NTRK2 mRNA
Genes: NTRK2; TRKB
Study 20877300 — Predictive Biomarker (PRD): GRIP1 mRNA
Genes: GRIP1
Study 20877300 — Predictive Biomarker (PRD): NXPH1 mRNA
Genes: NXPH1; NPH1; Nbla00697
Study 20877300 — Predictive Biomarker (PRD): ANK3 mRNA
Genes: ANK3
Study 20877300 — Predictive Biomarker (PRD): NTRK
Study 22676205 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22676205 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22676205 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20464479 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 15728210 — Surrogate Endpoint (SUR): Bone mineral density
Study 7956987 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21689371 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 12661789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12661789 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 3888591 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 21885625 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21885625 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9476677 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7945128 — Surrogate Endpoint (SUR): Blood pressure
Study 24950745 — Surrogate Endpoint (SUR): Blood pressure
Study 19860553 — Surrogate Endpoint (SUR): Blood pressure
Study 8706196 — Surrogate Endpoint (SUR): Blood pressure
Study 16032519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25369488 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20958145 — Surrogate Endpoint (SUR): Serum uric acid
Study 23782463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18587620 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 11283917 — Surrogate Endpoint (SUR): Bone mineral density
Study 9276357 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 9276357 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2885122 — Surrogate Endpoint (SUR): Plasma ammonia
Study 24742341 — Surrogate Endpoint (SUR): Blood pressure
Study 20142823 — Surrogate Endpoint (SUR): Blood pressure
Study 20142823 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28006816 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28006816 — Monitoring Biomarker (MOI): Cell-free DNA
Study 28006816 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15990456 — Predictive Biomarker (PRD): IFNAR1 mRNA
Genes: IFNAR1; IFNAR
Study 6100880 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6100880 — Surrogate Endpoint (SUR): Blood pressure
Study 31660693 — Predictive Biomarker (PRD): SST mRNA
Genes: SST