TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22695039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22695039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22695039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22695039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16170253 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 12538221 — Surrogate Endpoint (SUR): Blood pressure
Study 22476378 — Surrogate Endpoint (SUR): Bone mineral density
Study 17496732 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 17496732 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11412645 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 19954057 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 19954057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11316916 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6118215 — Surrogate Endpoint (SUR): Blood pressure
Study 26732026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25951165 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 12611754 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 10678926 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31888738 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 31888738 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 9116614 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9116614 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9116614 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9116614 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7907662 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7907662 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 7907662 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31092460 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24045669 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 21456072 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 9454190 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 31646623 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 29081151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29081151 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22855579 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 14973800 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9042869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9042869 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9042869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8037492 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 8037492 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26500139 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9274547 — Surrogate Endpoint (SUR): Blood pressure
Study 8436148 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31916979 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31916979 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 24241487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22527828 — Surrogate Endpoint (SUR): Bone mineral density
Study 1837113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26721782 — Surrogate Endpoint (SUR): Blood pressure
Study 22209388 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 2668148 — Monitoring Biomarker (MOI): HBV DNA
Study 21933752 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8580574 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 8580574 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 27221952 — Surrogate Endpoint (SUR): Blood pressure
Study 18996518 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24736243 — Surrogate Endpoint (SUR): Blood pressure
Study 24399583 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 10389843 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 1799761 — Surrogate Endpoint (SUR): Blood pressure
Study 28558702 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9815809 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 17329698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17329698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17329698 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9883463 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 2239758 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 908151 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 908151 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31521847 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25477161 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 7981845 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2247718 — Surrogate Endpoint (SUR): Serum creatinine
Study 28556284 — Surrogate Endpoint (SUR): Blood pressure
Study 25790672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23498169 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23498169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 23498169 — Safety Biomarker (SAF): miR-96
Genes: MIR96
Study 12732606 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30974489 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 27072591 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 27072591 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22677919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8623106 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 27786012 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27786012 — Surrogate Endpoint (SUR): Blood pressure
Study 29165093 — Surrogate Endpoint (SUR): Blood pressure
Study 29165093 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29165093 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29165093 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12373601 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12373601 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 15321118 — Surrogate Endpoint (SUR): Blood pressure
Study 7561554 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 24070232 — Surrogate Endpoint (SUR): Blood pressure
Study 9209250 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9209250 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 9209250 — Surrogate Endpoint (SUR): Serum potassium
Study 27126186 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19781112 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15866679 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 12873686 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 24750797 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 20486839 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15963088 — Surrogate Endpoint (SUR): Blood pressure
Study 27491227 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 20456478 — Surrogate Endpoint (SUR): Blood pressure
Study 17381666 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8406323 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3543231 — Surrogate Endpoint (SUR): Blood pressure
Study 29985080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25794984 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12576803 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 29378227 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 19808377 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17803204 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15468186 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22563440 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12671339 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19429735 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 15223991 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 9464734 — Surrogate Endpoint (SUR): Blood pressure
Study 31927774 — Predictive Biomarker (PRD): DUT mRNA
Genes: DUT
Study 26643000 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 31805967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30188739 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24776962 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24776962 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15461064 — Surrogate Endpoint (SUR): Blood pressure
Study 24265181 — Surrogate Endpoint (SUR): Blood pressure
Study 17442688 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 788737 — Surrogate Endpoint (SUR): Blood pressure
Study 21508007 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 22224253 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 22224253 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 19615944 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19615944 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 19615944 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 14872175 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 14872175 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 14872175 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 14872175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14872175 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 29024214 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 22434665 — Predictive Biomarker (PRD): DAPK1 mRNA
Genes: DAPK1; DAPK
Study 22434665 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 22434665 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19584683 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15002002 — Surrogate Endpoint (SUR): Blood pressure
Study 10589755 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1928220 — Surrogate Endpoint (SUR): Serum calcium
Study 12434950 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12434950 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 12434950 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7792736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31541251 — Predictive Biomarker (PRD): GPER1 mRNA
Genes: GPER1; CEPR; CMKRL2; DRY12; GPER; GPR30
Study 26383207 — Surrogate Endpoint (SUR): Blood pressure
Study 14764782 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30945490 — Predictive Biomarker (PRD): ST7 mRNA
Genes: ST7; FAM4A1; HELG; RAY1
Study 30334633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30334633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19057271 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19057271 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19057271 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8735151 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 22516666 — Surrogate Endpoint (SUR): Blood pressure
Study 10663363 — Surrogate Endpoint (SUR): Bone mineral density
Study 15679463 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 598366 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 11900290 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 1978880 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26840437 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22879630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3063268 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 3063268 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22773672 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 11938826 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30665517 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28128911 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25451321 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 11346808 — Surrogate Endpoint (SUR): Bone mineral density
Study 1745700 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 23158484 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 1209444 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1209444 — Surrogate Endpoint (SUR): Serum uric acid
Study 30548935 — Surrogate Endpoint (SUR): Serum creatinine
Study 22853014 — Predictive Biomarker (PRD): Hormone receptor
Study 29891223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26817716 — Surrogate Endpoint (SUR): Blood pressure
Study 2024541 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2024541 — Surrogate Endpoint (SUR): Blood pressure
Study 28626102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7736475 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2283639 — Surrogate Endpoint (SUR): Serum potassium
Study 30955310 — Surrogate Endpoint (SUR): Blood pressure
Study 27629070 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7982185 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28655794 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17028485 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15721722 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 15721722 — Surrogate Endpoint (SUR): Blood pressure
Study 29768139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16328288 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 16328288 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 25888664 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 25888664 — Surrogate Endpoint (SUR): Blood pressure
Study 17726570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17726570 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15274106 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11387347 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 3544839 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22543151 — Monitoring Biomarker (MOI): HBV DNA
Study 18461096 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9411335 — Surrogate Endpoint (SUR): Blood pressure
Study 6688450 — Surrogate Endpoint (SUR): Serum calcium
Study 22633824 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22633824 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11572048 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11572048 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29087093 — Surrogate Endpoint (SUR): Bacterial count
Study 18422390 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18422390 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16052221 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 16052221 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 14578234 — Surrogate Endpoint (SUR): Blood pressure
Study 22369095 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 22369095 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16398426 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 11736884 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29178564 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 23820246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8006274 — Surrogate Endpoint (SUR): Blood pressure
Study 2690923 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 2690923 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 28368340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28368340 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28368340 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 28368340 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28368340 — Safety Biomarker (SAF): Interleukin 1
Study 28368340 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15856859 — Surrogate Endpoint (SUR): Blood pressure
Study 2191978 — Surrogate Endpoint (SUR): Blood pressure
Study 23768206 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21665167 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 7589382 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25735561 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 15249794 — Surrogate Endpoint (SUR): Blood pressure
Study 3533421 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 25487220 — Surrogate Endpoint (SUR): Blood pressure
Study 12228196 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 9589294 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7979858 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7979858 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30622099 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28071865 — Surrogate Endpoint (SUR): Blood pressure
Study 9289439 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 29846693 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study 21566548 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 19594648 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19594648 — Surrogate Endpoint (SUR): Blood pressure
Study 11054523 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11054523 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25331894 — Surrogate Endpoint (SUR): Blood pressure
Study 30172037 — Surrogate Endpoint (SUR): Blood pressure
Study 25372582 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9459113 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 3202925 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25951632 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 25951632 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 30195124 — Surrogate Endpoint (SUR): Blood pressure
Study 30195124 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28418937 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 31393619 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31393619 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 31393619 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30156033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17316098 — Surrogate Endpoint (SUR): Blood pressure
Study 9541124 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9078536 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 2667597 — Surrogate Endpoint (SUR): Serum potassium
Study 8317653 — Surrogate Endpoint (SUR): Blood pressure