TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9509971 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7800170 — Surrogate Endpoint (SUR): Blood pressure
Study 2784382 — Safety Biomarker (SAF): Interleukin 1
Study 27073832 — Surrogate Endpoint (SUR): Bone mineral density
Study 15998278 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12706919 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12706919 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 11741217 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6365463 — Surrogate Endpoint (SUR): Blood pressure
Study 27117850 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 12173810 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3328986 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29795665 — Predictive Biomarker (PRD): APRT mRNA
Genes: APRT
Study 19439966 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19439966 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19439966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19439966 — Safety Biomarker (SAF): Interleukin 1
Study 19439966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15057894 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 11694151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2827044 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2827044 — Surrogate Endpoint (SUR): Blood pressure
Study 11257242 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 19647945 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 14694237 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 28225052 — Surrogate Endpoint (SUR): Bone mineral density
Study 21205384 — Surrogate Endpoint (SUR): Bone mineral density
Study 21205384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16613341 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14600814 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14600814 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9313596 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9313596 — Surrogate Endpoint (SUR): Serum creatinine
Study 9313596 — Surrogate Endpoint (SUR): Blood pressure
Study 8198055 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8198055 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23656707 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 3027905 — Surrogate Endpoint (SUR): Blood pressure
Study 25835002 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25835002 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 25835002 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 25835002 — Surrogate Endpoint (SUR): Blood pressure
Study 29713156 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 30107904 — Surrogate Endpoint (SUR): Blood pressure
Study 26784323 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25045936 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 25045936 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 22086300 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19292654 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19292654 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19292654 — Surrogate Endpoint (SUR): Blood pressure
Study 17485599 — Surrogate Endpoint (SUR): Blood pressure
Study 2527534 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 184377 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25466509 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21689393 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 21689393 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 9140801 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9140801 — Surrogate Endpoint (SUR): Blood pressure
Study 2142246 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 2142246 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 28825348 — Safety Biomarker (SAF): BDNF
Study 26831333 — Surrogate Endpoint (SUR): Blood pressure
Study 25233668 — Surrogate Endpoint (SUR): Blood pressure
Study 12077765 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 12077765 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 23226223 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 15469651 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3555650 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17591020 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27102490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20618247 — Surrogate Endpoint (SUR): Bone mineral density
Study 28122717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28122717 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 28122717 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 19150378 — Safety Biomarker (SAF): IL-6 and IL-10
Study 9218185 — Surrogate Endpoint (SUR): Blood pressure
Study 29895491 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29895491 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1575006 — Surrogate Endpoint (SUR): Blood pressure
Study 29171139 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27643296 — Surrogate Endpoint (SUR): Blood pressure
Study 23136163 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 2067505 — Surrogate Endpoint (SUR): Blood pressure
Study 26426636 — Surrogate Endpoint (SUR): Serum creatinine
Study 2285640 — Surrogate Endpoint (SUR): Blood pressure
Study 30651130 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 22612913 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 19528286 — Surrogate Endpoint (SUR): Serum creatinine
Study 14674937 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 14674937 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 18210765 — Surrogate Endpoint (SUR): Blood pressure
Study 7486097 — Surrogate Endpoint (SUR): Blood pressure
Study 26189118 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 17374703 — Surrogate Endpoint (SUR): Blood pressure
Study 15719220 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 9814462 — Surrogate Endpoint (SUR): Bone mineral density
Study 7665802 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 26895618 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26895618 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26895618 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study 17461726 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16602632 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10456462 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7604799 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 452941 — Surrogate Endpoint (SUR): Blood pressure
Study 30114658 — Predictive Biomarker (PRD): EXO1 mRNA
Genes: EXO1; EXOI; HEX1
Study 30114658 — Predictive Biomarker (PRD): DCLRE1A mRNA
Genes: DCLRE1A; KIAA0086; SNM1; SNM1A
Study 12719203 — Surrogate Endpoint (SUR): Blood pressure
Study 22431582 — Surrogate Endpoint (SUR): Blood pressure
Study 12214151 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26646828 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 14687360 — Surrogate Endpoint (SUR): Blood pressure
Study 8873503 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 1516840 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30362280 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25670530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25670530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23418947 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 23418947 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FBXO32 mRNA
Genes: FBXO32
Study 11306778 — Surrogate Endpoint (SUR): Blood pressure
Study 7942164 — Surrogate Endpoint (SUR): Bone mineral density
Study 2904754 — Surrogate Endpoint (SUR): Blood pressure
Study 2904754 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28628884 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 16144849 — Surrogate Endpoint (SUR): Blood pressure
Study 9174467 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9174467 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 9174467 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 30624598 — Surrogate Endpoint (SUR): Bone mineral density
Study 29739634 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26993331 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24495158 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8949690 — Predictive Biomarker (PRD): PAAT mRNA
Genes: PAAT; C10orf88
Study 2044395 — Surrogate Endpoint (SUR): Blood pressure
Study 6796714 — Surrogate Endpoint (SUR): Blood pressure
Study 16860698 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12664518 — Surrogate Endpoint (SUR): Blood pressure
Study 10326070 — Surrogate Endpoint (SUR): Bone mineral density
Study 25074698 — Surrogate Endpoint (SUR): Blood pressure
Study 12149661 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12149661 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30824956 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 19574102 — Surrogate Endpoint (SUR): Blood pressure
Study 2575369 — Surrogate Endpoint (SUR): Blood pressure
Study 26156651 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23774238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23774238 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10967698 — Surrogate Endpoint (SUR): Blood pressure
Study 8790198 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 27368882 — Predictive Biomarker (PRD): Hormone receptor
Study 10522131 — Surrogate Endpoint (SUR): Blood pressure
Study 1321859 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27516476 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 27516476 — Predictive Biomarker (PRD): NRF1 mRNA
Genes: NRF1
Study 27516476 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 27516476 — Predictive Biomarker (PRD): AKT2 mRNA
Genes: AKT2
Study 27516476 — Predictive Biomarker (PRD): PTPN1 mRNA
Genes: PTPN1; PTP1B
Study 27516476 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 16386524 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 16386524 — Surrogate Endpoint (SUR): Serum creatinine
Study 12048292 — Safety Biomarker (SAF): MTHFR
Study 7608861 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 29096835 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25862777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21498149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19249153 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19249153 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 19249153 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 9383182 — Surrogate Endpoint (SUR): Blood pressure
Study 29556903 — Surrogate Endpoint (SUR): Serum creatinine
Study 20226890 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12584366 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12584366 — Surrogate Endpoint (SUR): Blood pressure
Study 31957555 — Surrogate Endpoint (SUR): Serum testosterone
Study 31515191 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 22933501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21495900 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21495900 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11180010 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 11180010 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11180010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11180010 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11180010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11180010 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 10865416 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 10865416 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 21869730 — Safety Biomarker (SAF): MTHFR
Study 20569064 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16172596 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 9020535 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20195744 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17919634 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 1632166 — Surrogate Endpoint (SUR): Blood pressure
Study 31539267 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28215413 — Surrogate Endpoint (SUR): Blood pressure
Study 23270444 — Safety Biomarker (SAF): Reactive oxygen species
Study 8600888 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 15157948 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15157948 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 7920875 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31789711 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20505750 — Surrogate Endpoint (SUR): Blood pressure
Study 19081890 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29073785 — Surrogate Endpoint (SUR): Serum creatinine
Study 27091717 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21039933 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18560524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9189045 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 30457433 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 25306591 — Surrogate Endpoint (SUR): Bone mineral density
Study 10669150 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10669150 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8797400 — Surrogate Endpoint (SUR): Serum potassium
Study 21906546 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21906546 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16214825 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 16214825 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 31203726 — Surrogate Endpoint (SUR): Blood pressure
Study 27403645 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24606097 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19825207 — Surrogate Endpoint (SUR): Blood pressure
Study 23349102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 23349102 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 27595528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27595528 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 12872610 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 6113479 — Surrogate Endpoint (SUR): Blood pressure
Study 28544128 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25869284 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study 23677919 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7944416 — Predictive Biomarker (PRD): ALPK1 mRNA
Genes: ALPK1; KIAA1527; LAK
Study 7944416 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27711048 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15539964 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25560227 — Surrogate Endpoint (SUR): Blood pressure
Study 343181 — Predictive Biomarker (PRD): SHB mRNA
Genes: SHB
Study 15114770 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11590384 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 15933856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26400874 — Surrogate Endpoint (SUR): Blood pressure
Study 23755867 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10096047 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12707127 — Surrogate Endpoint (SUR): Blood pressure
Study 29049611 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 2526271 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 23257734 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 16407508 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16407508 — Surrogate Endpoint (SUR): Serum creatinine
Study 16407508 — Surrogate Endpoint (SUR): Blood pressure
Study 11320566 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24804364 — Surrogate Endpoint (SUR): Blood pressure
Study 29420997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18822620 — Surrogate Endpoint (SUR): Bone mineral density
Study 31522159 — Predictive Biomarker (PRD): ADAM8 mRNA
Genes: ADAM8; MS2
Study 23673091 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10993031 — Surrogate Endpoint (SUR): Bone mineral density
Study 1349485 — Surrogate Endpoint (SUR): Blood pressure
Study 25399975 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8167383 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8167383 — Surrogate Endpoint (SUR): Blood pressure
Study 31664959 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 26362286 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 23870300 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15516942 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19577936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18922381 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 12458654 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12458654 — Surrogate Endpoint (SUR): Blood pressure
Study 10520057 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1791485 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18001210 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10213125 — Surrogate Endpoint (SUR): Bone mineral density
Study 393299 — Surrogate Endpoint (SUR): Blood pressure
Study 7924466 — Surrogate Endpoint (SUR): Blood pressure
Study 3057036 — Surrogate Endpoint (SUR): Blood pressure
Study 23624215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23624215 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9527083 — Surrogate Endpoint (SUR): Blood pressure
Study 30551730 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 30551730 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 3440634 — Surrogate Endpoint (SUR): Serum potassium
Study 21621993 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 21621993 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12659241 — Surrogate Endpoint (SUR): Serum testosterone
Study 20499131 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15277317 — Surrogate Endpoint (SUR): Blood pressure
Study 11896110 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2283644 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2283644 — Surrogate Endpoint (SUR): Blood pressure
Study 25424121 — Surrogate Endpoint (SUR): Blood pressure
Study 25424121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22876543 — Surrogate Endpoint (SUR): Bone mineral density
Study 7671364 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7009103 — Surrogate Endpoint (SUR): Blood pressure
Study 24780643 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 24780643 — Surrogate Endpoint (SUR): Blood pressure
Study 19703317 — Surrogate Endpoint (SUR): Blood pressure
Study 19549743 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 19549743 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2971473 — Surrogate Endpoint (SUR): Blood pressure
Study 29880069 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 23549975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8430681 — Surrogate Endpoint (SUR): Serum creatinine