TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19822078 — Predictive Biomarker (PRD): ACKR1 mRNA
Genes: ACKR1; DARC; FY; GPD
Study 19822078 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19822078 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 14998241 — Surrogate Endpoint (SUR): Blood pressure
Study 7894117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 26431252 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11214746 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8708426 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 24210590 — Surrogate Endpoint (SUR): Serum creatinine
Study 15662235 — Surrogate Endpoint (SUR): Blood pressure
Study 27959333 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 11434074 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2680275 — Surrogate Endpoint (SUR): Blood pressure
Study 26342289 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 26342289 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 10699160 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8166887 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8166887 — Surrogate Endpoint (SUR): Blood pressure
Study 3535392 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28749822 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28749822 — Monitoring Biomarker (MOI): HBV DNA
Study 19450759 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 11134099 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 26403265 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 26403265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29986611 — Surrogate Endpoint (SUR): Bone mineral density
Study 25581207 — Surrogate Endpoint (SUR): Blood pressure
Study 21332653 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 21332653 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 21332653 — Safety Biomarker (SAF): CDA
Genes: CDD
Study 16915025 — Surrogate Endpoint (SUR): Blood pressure
Study 15060511 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15060511 — Surrogate Endpoint (SUR): Blood pressure
Study 9385475 — Surrogate Endpoint (SUR): Blood pressure
Study 3617239 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 27439527 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15987864 — Surrogate Endpoint (SUR): Blood pressure
Study 9815934 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 30765429 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25350916 — Surrogate Endpoint (SUR): Blood pressure
Study 31447226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31447226 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31447226 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30578873 — Predictive Biomarker (PRD): S100A7 mRNA
Genes: S100A7; PSOR1; S100A7C
Study 23326011 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 12202468 — Surrogate Endpoint (SUR): Bone mineral density
Study 30010481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27797437 — Surrogate Endpoint (SUR): Blood pressure
Study 24006085 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 3521277 — Surrogate Endpoint (SUR): Blood pressure
Study 27177859 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 23885105 — Surrogate Endpoint (SUR): Bone mineral density
Study 22180217 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12115219 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 24476082 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15999118 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11858450 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 9109467 — Surrogate Endpoint (SUR): Blood pressure
Study 24063257 — Surrogate Endpoint (SUR): Blood pressure
Study 21122660 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21122660 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15943568 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26613790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26342674 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26342674 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 26342674 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 26342674 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 7645930 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2529059 — Surrogate Endpoint (SUR): Blood pressure
Study 2529059 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21796066 — Surrogate Endpoint (SUR): Bone mineral density
Study 30390203 — Surrogate Endpoint (SUR): Blood pressure
Study 23903900 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 23903900 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 16340384 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 28672098 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 1826213 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1826213 — Surrogate Endpoint (SUR): Blood pressure
Study 17416765 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 17416765 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 29908359 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 29908359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28586279 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21062083 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 21062083 — Safety Biomarker (SAF): Cytochrome c
Study 10989266 — Surrogate Endpoint (SUR): Blood pressure
Study 9077073 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 7524759 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2884855 — Surrogate Endpoint (SUR): Blood pressure
Study 2884855 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15265377 — Surrogate Endpoint (SUR): Bone mineral density
Study 15265377 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15265377 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26933811 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 26933811 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 26933811 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26933811 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 24935932 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24935932 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24935932 — Pharmacodynamic Biomarker (PDY): GATA-type zinc finger protein 1
Genes: ZGLP1; GLP1
Study 21825083 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 21825083 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 8864421 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12883194 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 12883194 — Surrogate Endpoint (SUR): Serum creatinine
Study 12883194 — Surrogate Endpoint (SUR): Blood pressure
Study 12883194 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12883194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30058901 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27257981 — Safety Biomarker (SAF): Hyaluronic acid
Study 18034666 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 18034666 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18034666 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7607138 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26356393 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23315029 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23315029 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 28120486 — Predictive Biomarker (PRD): PDE9A mRNA
Genes: PDE9A
Study 28120486 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 17022857 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11087880 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29381544 — Safety Biomarker (SAF): Hyaluronic acid
Study 24214315 — Surrogate Endpoint (SUR): Bone mineral density
Study 28216083 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25117806 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19646194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15730685 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15730685 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 11518688 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11518688 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 11518688 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 29235360 — Safety Biomarker (SAF): Hyaluronic acid
Study 22039325 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 31838029 — Surrogate Endpoint (SUR): Serum sodium
Study 17112361 — Surrogate Endpoint (SUR): Blood pressure
Study 26301519 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 1822761 — Surrogate Endpoint (SUR): Blood pressure
Study 9433391 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19709634 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 17482439 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 17482439 — Predictive Biomarker (PRD): COX5B mRNA
Genes: COX5B
Study 9890612 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 1897469 — Surrogate Endpoint (SUR): Serum potassium
Study 18305265 — Surrogate Endpoint (SUR): Blood pressure
Study 27143662 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 24716628 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24716628 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24716628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23741071 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 16640102 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30670009 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 17477110 — Surrogate Endpoint (SUR): Blood pressure
Study 16622259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7812703 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31729127 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31729127 — Surrogate Endpoint (SUR): Blood pressure
Study 30663196 — Surrogate Endpoint (SUR): Blood pressure
Study 30663196 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25675123 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 3140744 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 3140744 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31513665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31513665 — Safety Biomarker (SAF): Interleukin 1
Study 31513665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26643548 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22912456 — Predictive Biomarker (PRD): FMO3 mRNA
Genes: FMO3
Study 7884952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 651762 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 23404919 — Predictive Biomarker (PRD): LEAP2 mRNA
Genes: LEAP2
Study 19832114 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17576783 — Surrogate Endpoint (SUR): Blood pressure
Study 9702848 — Surrogate Endpoint (SUR): Blood pressure
Study 9702848 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1890447 — Surrogate Endpoint (SUR): Blood pressure
Study 30633218 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 29507777 — Surrogate Endpoint (SUR): Blood pressure
Study 27089170 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 22443165 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 31035469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31035469 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31035469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30284506 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 25113835 — Safety Biomarker (SAF): Reactive oxygen species
Study 22674050 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 8355039 — Predictive Biomarker (PRD): AGL mRNA
Genes: AGL; GDE
Study 8355039 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 8355039 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23486907 — Surrogate Endpoint (SUR): Serum potassium
Study 12761258 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12761258 — Surrogate Endpoint (SUR): Serum creatinine
Study 10998076 — Surrogate Endpoint (SUR): Blood pressure
Study 2821056 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28577673 — Surrogate Endpoint (SUR): Blood pressure
Study 21146883 — Safety Biomarker (SAF): Reactive oxygen species
Study 21146883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11328912 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11328912 — Surrogate Endpoint (SUR): Serum uric acid
Study 11328912 — Surrogate Endpoint (SUR): Blood pressure
Study 11328912 — Surrogate Endpoint (SUR): Serum potassium
Study 8381847 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 23715032 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20942650 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10506596 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1996435 — Surrogate Endpoint (SUR): Blood pressure
Study 6436526 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 6436526 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25269777 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15515655 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 9753069 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 3281058 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 3281058 — Surrogate Endpoint (SUR): Blood pressure
Study 20729007 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16306801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16306801 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 320809 — Surrogate Endpoint (SUR): Blood pressure
Study 17067452 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 15037413 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7965279 — Surrogate Endpoint (SUR): Blood pressure
Study 7965279 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15965989 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12376472 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 12376472 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 11306519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11306519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22409379 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 19958075 — Surrogate Endpoint (SUR): Blood pressure
Study 17907102 — Surrogate Endpoint (SUR): Blood pressure
Study 16076985 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27626518 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 10100063 — Surrogate Endpoint (SUR): Blood pressure
Study 1725033 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28611080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23176668 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23176668 — Surrogate Endpoint (SUR): Blood pressure
Study 15172088 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15172088 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26238412 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 26238412 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26238412 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 8616479 — Surrogate Endpoint (SUR): Blood pressure
Study 2285635 — Surrogate Endpoint (SUR): Serum potassium
Study 7137070 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7137070 — Surrogate Endpoint (SUR): Blood pressure
Study 26190286 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26190286 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23415416 — Surrogate Endpoint (SUR): Blood pressure
Study 21243500 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 15125213 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 31559483 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31212058 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 19150703 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8357556 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20576719 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20576719 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 20576719 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 20576719 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 20576719 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 20576719 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 16353054 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11865833 — Predictive Biomarker (PRD): SFPQ mRNA
Genes: SFPQ; PSF
Study 9741018 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29957136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17279435 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17279435 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3182964 — Surrogate Endpoint (SUR): Serum calcium
Study 24341368 — Surrogate Endpoint (SUR): Blood pressure
Study 20720348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20720348 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20720348 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26267600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10972907 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10972907 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8317948 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 8317948 — Surrogate Endpoint (SUR): Blood pressure
Study 26535593 — Surrogate Endpoint (SUR): Serum uric acid
Study 31172823 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 23323877 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14718678 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 19661695 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19661695 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14688594 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9768652 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 21105835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16266859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16266859 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31554937 — Surrogate Endpoint (SUR): Blood pressure
Study 31554937 — Surrogate Endpoint (SUR): Serum potassium
Study 18375792 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18375792 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 10889591 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10889591 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9096917 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9096917 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9096917 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10469680 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 8915224 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8915224 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26792933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2