TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9640129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27992949 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 22041866 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 22295812 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 22295812 — Surrogate Endpoint (SUR): Blood pressure
Study 12394941 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30306731 — Predictive Biomarker (PRD): CTSW mRNA
Genes: CTSW
Study 30306731 — Predictive Biomarker (PRD): PCSK4 mRNA
Genes: PCSK4; PC4; UNQ2757/PRO6496
Study 30306731 — Predictive Biomarker (PRD): LRRC8D mRNA
Genes: LRRC8D; LRRC5; UNQ213/PRO239
Study 30306731 — Predictive Biomarker (PRD): TNFRSF18 mRNA
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study 30306731 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study 30306731 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 16371798 — Safety Biomarker (SAF): Hyaluronic acid
Study 2554837 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 20348496 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 18053592 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18053592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29873009 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 29873009 — Predictive Biomarker (PRD): SPHK1 mRNA
Genes: SPHK1; SK1; SPHK; SPK
Study 28319109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19851157 — Surrogate Endpoint (SUR): Blood pressure
Study 26452060 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 26452060 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 26452060 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26452060 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 26452060 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 26452060 — Predictive Biomarker (PRD): Hormone receptor
Study 1101615 — Surrogate Endpoint (SUR): Blood pressure
Study 15333165 — Surrogate Endpoint (SUR): Blood pressure
Study 30176891 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 27471203 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 27471203 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 550366 — Surrogate Endpoint (SUR): Serum calcium
Study 25839338 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 9875910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9875910 — Safety Biomarker (SAF): IL-6 and IL-10
Study 23469947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 29970142 — Safety Biomarker (SAF): BDNF
Study 29970142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29970142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29970142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19822605 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17599422 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17599422 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17599422 — Surrogate Endpoint (SUR): Blood pressure
Study 12925048 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12925048 — Surrogate Endpoint (SUR): Blood pressure
Study 23060426 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23060426 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12808177 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1808632 — Surrogate Endpoint (SUR): Blood pressure
Study 1808632 — Surrogate Endpoint (SUR): Serum potassium
Study 17699310 — Surrogate Endpoint (SUR): Serum creatinine
Study 16006297 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7534216 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1903847 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26804646 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 20167991 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20167991 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 20167991 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 30786336 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22383630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22383630 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17315049 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17315049 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25939894 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18593517 — Surrogate Endpoint (SUR): Blood pressure
Study 27614727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22968626 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23521375 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15757015 — Surrogate Endpoint (SUR): Bone mineral density
Study 9350383 — Surrogate Endpoint (SUR): Blood pressure
Study 8363027 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22579428 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20215759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18514303 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15843280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15843280 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15843280 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2410224 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31648967 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 31648967 — Predictive Biomarker (PRD): MARCKSL1 mRNA
Genes: MARCKSL1; MLP; MRP
Study 31648967 — Predictive Biomarker (PRD): DEFA1 mRNA
Genes: DEFA1; DEF1; DEFA2; MRS; DEFA1B
Study 16708045 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 23690416 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 23690416 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 18157994 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 12111283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7979464 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23864535 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23864535 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 22789766 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22789766 — Surrogate Endpoint (SUR): Blood pressure
Study 15831640 — Surrogate Endpoint (SUR): Blood pressure
Study 21114797 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20048189 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 20048189 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8061842 — Surrogate Endpoint (SUR): Blood pressure
Study 31726193 — Surrogate Endpoint (SUR): Blood pressure
Study 25289793 — Surrogate Endpoint (SUR): Blood pressure
Study 21597242 — Surrogate Endpoint (SUR): Serum creatinine
Study 19339720 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19339720 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2874906 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29102263 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 22559322 — Surrogate Endpoint (SUR): Blood pressure
Study 9727569 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12236631 — Surrogate Endpoint (SUR): Blood pressure
Study 30143002 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 10603633 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27762088 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25913905 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19232755 — Surrogate Endpoint (SUR): Blood pressure
Study 9652426 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11977539 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 2406330 — Surrogate Endpoint (SUR): Serum calcium
Study 6988522 — Surrogate Endpoint (SUR): Serum creatinine
Study 23348146 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 21186977 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23381958 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21690070 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17288327 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 9398103 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9398103 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 28379925 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16846450 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 12970916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12970916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27060050 — Surrogate Endpoint (SUR): Bone mineral density
Study 24182734 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 25693012 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19506526 — Surrogate Endpoint (SUR): Blood pressure
Study 19506526 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3541419 — Surrogate Endpoint (SUR): Blood pressure
Study 9333111 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3780286 — Surrogate Endpoint (SUR): Blood pressure
Study 30896414 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 22399081 — Safety Biomarker (SAF): Hyaluronic acid
Study 20466440 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 17678567 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 17678567 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12588776 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12588776 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8901654 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8901654 — Surrogate Endpoint (SUR): Blood pressure
Study 28711556 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 19898218 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29226727 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study 2035557 — Surrogate Endpoint (SUR): Blood pressure
Study 26182947 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 19178788 — Surrogate Endpoint (SUR): Blood pressure
Study 17382697 — Surrogate Endpoint (SUR): Blood pressure
Study 17382697 — Surrogate Endpoint (SUR): Serum potassium
Study 17382697 — Surrogate Endpoint (SUR): Serum uric acid
Study 3292597 — Surrogate Endpoint (SUR): Blood pressure
Study 29478187 — Surrogate Endpoint (SUR): Blood pressure
Study 25281492 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16443517 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study 14518596 — Surrogate Endpoint (SUR): Bone mineral density
Study 8844502 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1530798 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31254849 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 12365090 — Surrogate Endpoint (SUR): Blood pressure
Study 7866482 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 2527537 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2527537 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22135385 — Predictive Biomarker (PRD): KIF6 mRNA
Genes: KIF6; C6orf102
Study 17242096 — Surrogate Endpoint (SUR): Blood pressure
Study 28353407 — Predictive Biomarker (PRD): ACY3 mRNA
Genes: ACY3; ASPA2
Study 28353407 — Predictive Biomarker (PRD): NPHS1 mRNA
Genes: NPHS1; NPHN
Study 25993594 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 17985810 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9869018 — Surrogate Endpoint (SUR): Blood pressure
Study 28957699 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study 28957699 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 16870812 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 25187003 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24083759 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25335123 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 18715755 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 16632019 — Surrogate Endpoint (SUR): Serum potassium
Study 16632019 — Surrogate Endpoint (SUR): Serum sodium
Study 12955758 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10998482 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1619204 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1619204 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9118819 — Surrogate Endpoint (SUR): Blood pressure
Study 12633131 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 19119703 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 1378141 — Surrogate Endpoint (SUR): Blood pressure
Study 30030308 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 26838248 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22532515 — Surrogate Endpoint (SUR): Bone mineral density
Study 1675877 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1648597 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 24250305 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 10668837 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1593852 — Surrogate Endpoint (SUR): Serum creatinine
Study 24356073 — Surrogate Endpoint (SUR): Blood pressure
Study 22207268 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 12221159 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 8554732 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 17298705 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 17298705 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 17298705 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 3316514 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29172862 — Surrogate Endpoint (SUR): Blood pressure
Study 26221061 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 26221061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23024098 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18200020 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18200020 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23371291 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 19955069 — Surrogate Endpoint (SUR): Blood pressure
Study 15119636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15119636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11515707 — Surrogate Endpoint (SUR): Blood pressure
Study 11233385 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 8827784 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 8827784 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 3910116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22743670 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 28341415 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 25981372 — Predictive Biomarker (PRD): ID2 mRNA
Genes: ID2; BHLHB26
Study 25981372 — Predictive Biomarker (PRD): ID4 mRNA
Genes: ID4; BHLHB27
Study 18843280 — Surrogate Endpoint (SUR): Blood pressure
Study 29996883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29996883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2201256 — Surrogate Endpoint (SUR): Blood pressure
Study 14747211 — Surrogate Endpoint (SUR): Blood pressure
Study 14725687 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 14725687 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 14725687 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 14725687 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10506726 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 27101551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27101551 — Monitoring Biomarker (MOI): Procalcitonin
Study 27101551 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 19053944 — Safety Biomarker (SAF): Reactive oxygen species
Study 19053944 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17202116 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7543348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7543348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30926298 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29962179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17206698 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 29473908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29473908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29473908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30636072 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20113825 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20113825 — Predictive Biomarker (PRD): Hormone receptor
Study 15471363 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15471363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15471363 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11531934 — Surrogate Endpoint (SUR): Bone mineral density
Study 3071594 — Surrogate Endpoint (SUR): Blood pressure
Study 29781109 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29781109 — Surrogate Endpoint (SUR): Blood pressure
Study 18408580 — Surrogate Endpoint (SUR): Serum creatinine
Study 12459936 — Surrogate Endpoint (SUR): Bone mineral density
Study 10379611 — Surrogate Endpoint (SUR): Blood pressure
Study 8540451 — Surrogate Endpoint (SUR): Blood pressure
Study 15849222 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12040975 — Surrogate Endpoint (SUR): Blood pressure
Study 28177498 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27813452 — Safety Biomarker (SAF): CREM mRNA
Genes: CREM
Study 25483701 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 7989481 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 29090685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29090685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24548399 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22027736 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 18303156 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 10352330 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7856699 — Surrogate Endpoint (SUR): Blood pressure
Study 6889432 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17914545 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 28669167 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 15564114 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 10938584 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH