TrialPanorama/TrialPanorama-database huggingface dataset:
Study 14725594 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9769277 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 7508697 — Surrogate Endpoint (SUR): Blood pressure
Study 2826714 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 21978765 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12559677 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12559677 — Surrogate Endpoint (SUR): Blood pressure
Study 12559677 — Surrogate Endpoint (SUR): Serum creatinine
Study 27142462 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 25740399 — Surrogate Endpoint (SUR): Blood pressure
Study 10340838 — Surrogate Endpoint (SUR): Blood pressure
Study 7594023 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7594023 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30232627 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 27957785 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 10231449 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 29077900 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18676757 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1876282 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1876282 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 27795368 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 18615103 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 330322 — Surrogate Endpoint (SUR): Blood pressure
Study 31343947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23258530 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 9701409 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 2811065 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 22004426 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8815563 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25336915 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 3142719 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30890624 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21746765 — Surrogate Endpoint (SUR): Blood pressure
Study 11793426 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 11793426 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 17885543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12237621 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9665228 — Surrogate Endpoint (SUR): Blood pressure
Study 21972268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17254485 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 16342093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12505222 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 12505222 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7721386 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7721386 — Surrogate Endpoint (SUR): Blood pressure
Study 22935043 — Surrogate Endpoint (SUR): Blood pressure
Study 3913756 — Surrogate Endpoint (SUR): Blood pressure
Study 3913756 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3913756 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24938404 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 24938404 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 24938404 — Predictive Biomarker (PRD): SYNM mRNA
Genes: SYNM; DMN; KIAA0353; SYN
Study 10869893 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 1547922 — Surrogate Endpoint (SUR): Blood pressure
Study 26892713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11012909 — Surrogate Endpoint (SUR): Blood pressure
Study 1575056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31228455 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12891305 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12891305 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12891305 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3574823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8040124 — Surrogate Endpoint (SUR): Serum creatinine
Study 31389278 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 28597102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25078334 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 2266755 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7395780 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 24000594 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16433794 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 16433794 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 26521887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26521887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26521887 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 26521887 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 22545386 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18548178 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18548178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12947315 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 17462827 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 9641475 — Surrogate Endpoint (SUR): Blood pressure
Study 28327932 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 28327932 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 26123682 — Surrogate Endpoint (SUR): Blood pressure
Study 24019545 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 24019545 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24019545 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19500510 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 19500510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19500510 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2412040 — Surrogate Endpoint (SUR): Blood pressure
Study 2412040 — Surrogate Endpoint (SUR): Serum potassium
Study 2412040 — Surrogate Endpoint (SUR): Serum creatinine
Study 24381054 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20458906 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20458906 — Surrogate Endpoint (SUR): Blood pressure
Study 10367614 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 8897388 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 30985534 — Surrogate Endpoint (SUR): Blood pressure
Study 8424516 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24916176 — Predictive Biomarker (PRD): EBP mRNA
Genes: EBP
Study 18221441 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 12684649 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 1978025 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 155097 — Surrogate Endpoint (SUR): Blood pressure
Study 30616380 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 23604707 — Surrogate Endpoint (SUR): Blood pressure
Study 22136960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21318452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16483549 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12879276 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9350368 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29240652 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15284729 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9251612 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29878044 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 29878044 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 29878044 — Predictive Biomarker (PRD): FADS3 mRNA
Genes: FADS3; CYB5RP
Study 22685164 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18576906 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18576906 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18576906 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31764732 — Surrogate Endpoint (SUR): Blood pressure
Study 1558501 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24522489 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 17668530 — Safety Biomarker (SAF): Reactive oxygen species
Study 15383192 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15383192 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15383192 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15383192 — Surrogate Endpoint (SUR): Blood pressure
Study 26894175 — Safety Biomarker (SAF): Hyaluronic acid
Study 11991271 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 7128220 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7128220 — Surrogate Endpoint (SUR): Blood pressure
Study 11584850 — Safety Biomarker (SAF): Hyaluronic acid
Study 30172038 — Surrogate Endpoint (SUR): Blood pressure
Study 12667969 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 3890521 — Surrogate Endpoint (SUR): Serum sodium
Study 30221485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20484150 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 12859220 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9187778 — Surrogate Endpoint (SUR): Blood pressure
Study 30768404 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 19844185 — Surrogate Endpoint (SUR): Blood pressure
Study 10543667 — Surrogate Endpoint (SUR): Blood pressure
Study 10543667 — Surrogate Endpoint (SUR): Serum creatinine
Study 1723446 — Surrogate Endpoint (SUR): Blood pressure
Study 15462110 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11208680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8989010 — Surrogate Endpoint (SUR): Blood pressure
Study 26372383 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 26372383 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17443852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17443852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28181167 — Predictive Biomarker (PRD): EEF2 mRNA
Genes: EEF2; EF2
Study 28181167 — Predictive Biomarker (PRD): COL18A1 mRNA
Genes: COL18A1
Study 28181167 — Predictive Biomarker (PRD): IL4I1 mRNA
Genes: IL4I1; FIG1; UNQ636/PRO1265
Study 28181167 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study 28181167 — Predictive Biomarker (PRD): PLAGL1 mRNA
Genes: PLAGL1; LOT1; ZAC
Study 28181167 — Predictive Biomarker (PRD): IFRD1 mRNA
Genes: IFRD1
Study 28181167 — Predictive Biomarker (PRD): MAPKAPK2 mRNA
Genes: MAPKAPK2
Study 28181167 — Predictive Biomarker (PRD): PPARGC1B mRNA
Genes: PPARGC1B; PERC; PGC1; PGC1B; PPARGC1
Study 28181167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28181167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20142584 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1827709 — Surrogate Endpoint (SUR): Serum potassium
Study 6456960 — Surrogate Endpoint (SUR): Blood pressure
Study 31665001 — Surrogate Endpoint (SUR): Blood pressure
Study 20947097 — Surrogate Endpoint (SUR): Blood pressure
Study 10971827 — Monitoring Biomarker (MOI): HBV DNA
Study 8627059 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31168999 — Safety Biomarker (SAF): Hyaluronic acid
Study 29420536 — Surrogate Endpoint (SUR): Serum creatinine
Study 10522982 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28143919 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 28143919 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 19890693 — Surrogate Endpoint (SUR): Blood pressure
Study 17029975 — Pharmacodynamic Biomarker (PDY): Peripheral myelin protein 22
Genes: PMP22; GAS3
Study 15252821 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20627289 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 29903900 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 25236783 — Surrogate Endpoint (SUR): Blood pressure
Study 10691822 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 21556816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21556816 — Surrogate Endpoint (SUR): Blood pressure
Study 21556816 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11780237 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 20814766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12469271 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9187185 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2865930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30667283 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30667283 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16162440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12941195 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 12941195 — Surrogate Endpoint (SUR): Bone mineral density
Study 8671814 — Surrogate Endpoint (SUR): Blood pressure
Study 25153328 — Surrogate Endpoint (SUR): Blood pressure
Study 22774385 — Surrogate Endpoint (SUR): Blood pressure
Study 12185427 — Predictive Biomarker (PRD): WBP2NL mRNA
Genes: WBP2NL; PAWP
Study 7120373 — Surrogate Endpoint (SUR): Blood pressure
Study 29975953 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26173850 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 24739131 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24739131 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1597230 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31374191 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 31374191 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 11502792 — Surrogate Endpoint (SUR): Serum testosterone
Study 16915030 — Surrogate Endpoint (SUR): Blood pressure
Study 16915030 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 2045142 — Surrogate Endpoint (SUR): Blood pressure
Study 23598172 — Surrogate Endpoint (SUR): Blood pressure
Study 20975285 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 12867568 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 1343282 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27653814 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23093587 — Surrogate Endpoint (SUR): Blood pressure
Study 20733135 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15110902 — Surrogate Endpoint (SUR): Blood pressure
Study 29461422 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29461422 — Predictive Biomarker (PRD): EDAR mRNA
Genes: EDAR; DL
Study 15870217 — Surrogate Endpoint (SUR): Serum creatinine
Study 15870217 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15870217 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15870217 — Surrogate Endpoint (SUR): Blood pressure
Study 15870217 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8173700 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8173700 — Surrogate Endpoint (SUR): Blood pressure
Study 29066444 — Surrogate Endpoint (SUR): Blood pressure
Study 21969500 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21969500 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24125620 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 6849473 — Surrogate Endpoint (SUR): Blood pressure
Study 24449597 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 12509555 — Surrogate Endpoint (SUR): Blood pressure
Study 11005942 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 8883119 — Surrogate Endpoint (SUR): Bone mineral density
Study 3917316 — Surrogate Endpoint (SUR): Blood pressure
Study 31369392 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 31369392 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 18312743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15562388 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15562388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24176024 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 24176024 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 24176024 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 24176024 — Predictive Biomarker (PRD): LIPG mRNA
Genes: LIPG; UNQ387/PRO719
Study 22218119 — Surrogate Endpoint (SUR): Serum creatinine
Study 10551702 — Surrogate Endpoint (SUR): Blood pressure
Study 24718702 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 24718702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27107153 — Predictive Biomarker (PRD): Hormone receptor
Study 20408346 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 17588826 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12422101 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9854453 — Surrogate Endpoint (SUR): Blood pressure
Study 9854453 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7832192 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31813388 — Surrogate Endpoint (SUR): Blood pressure
Study 11413085 — Surrogate Endpoint (SUR): Blood pressure
Study 23436914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23436914 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2387655 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 30356378 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 24196555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20406831 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11411960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9839852 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22733239 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 3092976 — Surrogate Endpoint (SUR): Blood pressure
Study 25120329 — Surrogate Endpoint (SUR): Blood pressure
Study 23206408 — Surrogate Endpoint (SUR): Serum creatinine
Study 15531937 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 30541346 — Surrogate Endpoint (SUR): Blood pressure
Study 19503784 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11220888 — Surrogate Endpoint (SUR): Blood pressure
Study 9750602 — Surrogate Endpoint (SUR): Blood pressure
Study 30513108 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29137628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29137628 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29137628 — Safety Biomarker (SAF): IL-6 and IL-10
Study 24924416 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24924416 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 24924416 — Predictive Biomarker (PRD): Hormone receptor
Study 24924416 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24924416 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF