TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03599609 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03599609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00159692 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04203095 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03593109 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03593109 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT00358176 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02314780 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT02314780 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01320059 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03319979 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study NCT03319979 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study NCT01015560 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT00000145 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05899439 — Predictive Biomarker (PRD): IFIH1 mRNA
Genes: IFIH1; MDA5; RH116
Study NCT05899439 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study NCT06443372 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study NCT04071197 — Predictive Biomarker (PRD): ATP8B1 mRNA
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study NCT00005377 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00839904 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00113945 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT00113945 — Surrogate Endpoint (SUR): Serum calcium
Study NCT03505034 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05170061 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04950452 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT02096601 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT03208777 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT02984202 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT00285428 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04657471 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00964587 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03927573 — Predictive Biomarker (PRD): PSCA mRNA
Genes: PSCA; UNQ206/PRO232
Study NCT03057990 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT04610541 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT04782336 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00204711 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study NCT02919709 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05661006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03146208 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03146208 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02587988 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01104597 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02875886 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00402376 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03079011 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03079011 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04571359 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT02934256 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT03629379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02762695 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04125446 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT02870803 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT00698009 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01737827 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00633971 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT03689582 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04206891 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT03014076 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03014076 — Predictive Biomarker (PRD): GP2 mRNA
Genes: GP2
Study NCT03014076 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01835457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01835457 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study NCT01835457 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT00003575 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00003575 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study NCT00003575 — Safety Biomarker (SAF): Interleukin 12
Study NCT04039399 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06133400 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02103244 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04831541 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04294927 — Predictive Biomarker (PRD): DNMBP mRNA
Genes: DNMBP; ARHGEF36; KIAA1010; TUBA
Study NCT02086604 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00367250 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00367250 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02338973 — Predictive Biomarker (PRD): NR2E3 mRNA
Genes: NR2E3; PNR; RNR
Study NCT02338973 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00817726 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT03374527 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04247763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05333692 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02984293 — Predictive Biomarker (PRD): LILRB5 mRNA
Genes: LILRB5; LIR8
Study NCT03006146 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01244854 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02047903 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02047903 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03016312 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00506259 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study NCT03880292 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04196179 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study NCT02592408 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT03986281 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04619251 — Predictive Biomarker (PRD): UGT2B17 mRNA
Genes: UGT2B17
Study NCT01852253 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00152880 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00679029 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00679029 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02022995 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02022995 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03435536 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04314557 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02372578 — Predictive Biomarker (PRD): PDPN mRNA
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study NCT02330406 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01421017 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT02401685 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01711073 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02537002 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04678089 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study NCT04678089 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study NCT02732457 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00701532 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT01681888 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT04750785 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study NCT02938091 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study NCT00557765 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01069692 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT02842320 — Predictive Biomarker (PRD): IL1RAP mRNA
Genes: IL1RAP; C3orf13; IL1R3
Study NCT01052220 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04447573 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04675385 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02904031 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03573934 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03932877 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT03461003 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03458936 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study NCT02648490 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03552432 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT00551590 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00551590 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03958383 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03781050 — Predictive Biomarker (PRD): STK11 mRNA
Genes: STK11; LKB1; PJS
Study NCT00690612 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00607685 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03432507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04034823 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04072042 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT04397991 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study NCT01325376 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04082546 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT02649140 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT02663518 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT00353522 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT02856477 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT05379478 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00626132 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00003601 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT03176823 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT03176823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00559390 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02989701 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02989701 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01611805 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study NCT03421626 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03421626 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01583699 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT00405925 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00005270 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01498159 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00305331 — Safety Biomarker (SAF): DRD2
Study NCT03545503 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01683656 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01075802 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01075802 — Safety Biomarker (SAF): CYP2D6
Genes: CPD6; P450-DB1; CYP2D; P450C2D
Study NCT03704246 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT01744392 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05468892 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00528736 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01556191 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01556191 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01556191 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT01556191 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study NCT01151410 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03642925 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02586025 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06722612 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02944136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02630602 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02141451 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT02810587 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02810587 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02769767 — Predictive Biomarker (PRD): GPC5 mRNA
Genes: GPC5
Study NCT02769767 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02769767 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study NCT02769767 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study NCT03979586 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03594201 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00561132 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02821741 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04392401 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01800032 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT02567773 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02388854 — Predictive Biomarker (PRD): WNT4 mRNA
Genes: WNT4; UNQ426/PRO864
Study NCT02368665 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03367650 — Predictive Biomarker (PRD): SLA mRNA
Genes: SLA; SLAP; SLAP1
Study NCT05101031 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01431625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01431625 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01431625 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01431625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01431625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04470544 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT03599531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03599531 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01156480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01835418 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02304484 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01193426 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01193426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01616745 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT01204398 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00883363 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00546624 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT00546624 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02807103 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04034446 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04034446 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03218826 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03218826 — Predictive Biomarker (PRD): PIK3CB mRNA
Genes: PIK3CB; PIK3C1
Study NCT03503461 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study NCT02684773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02684773 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02684773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02684773 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01808859 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00558428 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01945021 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study NCT01945021 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT01966029 — Predictive Biomarker (PRD): GALNS mRNA
Genes: GALNS
Study NCT00098501 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01259817 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT01051674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01742273 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT03118583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03118583 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04390126 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04390126 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02326064 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT02326064 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT02794649 — Predictive Biomarker (PRD): PHC1 mRNA
Genes: PHC1; EDR1; PH1
Study NCT01963910 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT00611689 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03857165 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00251459 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02605486 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02010359 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT02980731 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT00591370 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03975777 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT03975777 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study NCT03975777 — Predictive Biomarker (PRD): NKRF mRNA
Genes: NKRF; ITBA4; NRF
Study NCT03975777 — Predictive Biomarker (PRD): TFAM mRNA
Genes: TFAM; TCF6; TCF6L2
Study NCT03975777 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT03975777 — Predictive Biomarker (PRD): TFB1M mRNA
Genes: TFB1M; CGI-75
Study NCT03975777 — Predictive Biomarker (PRD): TFB2M mRNA
Genes: TFB2M; NS5ATP5
Study NCT03975777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): NRF2 mRNA
Genes: NFE2L2; NRF2
Study NCT03975777 — Safety Biomarker (SAF): Cytochrome c
Study NCT00817713 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00923260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00923260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01553773 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01593332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04019223 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study NCT00377442 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study NCT03907124 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT03907124 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT03907124 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1