TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03886597 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01969071 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02875002 — Predictive Biomarker (PRD): PLK1 mRNA
Genes: PLK1; PLK
Study NCT04613609 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04613609 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01577342 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01734226 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03787992 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04446741 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01730053 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00728858 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00728858 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT02136771 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00155168 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT01642394 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02359721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02359721 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT02359721 — Surrogate Endpoint (SUR): Bacterial count
Study NCT00451763 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02994030 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03415399 — Predictive Biomarker (PRD): DCLRE1C mRNA
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study NCT03415399 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03107988 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03107988 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT01864902 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT02480673 — Predictive Biomarker (PRD): CHIA mRNA
Genes: CHIA
Study NCT01854190 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04524507 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01353365 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02354677 — Predictive Biomarker (PRD): SCGB1A1 mRNA
Genes: SCGB1A1; CC10; CCSP; UGB
Study NCT02046434 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT01251796 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01542866 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01464528 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02396394 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05404516 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01545531 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT01545531 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00937976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00937976 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04410549 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02297555 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01566578 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01566578 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04034589 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04034589 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04034589 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04034589 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02550652 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04654195 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT04654195 — Predictive Biomarker (PRD): SLC22A16 mRNA
Genes: SLC22A16; OCT6
Study NCT00288626 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03525223 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02618668 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01243489 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01243489 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02788175 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04497701 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02674555 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02674555 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03672955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04065633 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04065633 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02063477 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02063477 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02242877 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00413010 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00949013 — Predictive Biomarker (PRD): ALDH1A1 mRNA
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study NCT02537080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04981028 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT04898218 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03515200 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03515200 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT03273998 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00340444 — Predictive Biomarker (PRD): NOD2 mRNA
Genes: NOD2; CARD15; IBD1
Study NCT03724604 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01643473 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03205085 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study NCT03205085 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT03205085 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT00741468 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01360177 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT03755908 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02133313 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study NCT02133313 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01532362 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01532362 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT02022618 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01449747 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03930992 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01125566 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00053378 — Surrogate Endpoint (SUR): Serum calcium
Study NCT04556422 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02772900 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00634647 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT03747484 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03747484 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT00404001 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03459053 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study NCT03459053 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00269841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02212730 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02854397 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study NCT00899158 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01874938 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01826435 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01599260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01599260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01599260 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04516551 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01044901 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03010020 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04031885 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04031885 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04031885 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04031885 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04031885 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02956278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT02782208 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00092521 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01162005 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04011059 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01042847 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT02230644 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03327064 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study NCT01980719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03468322 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT03468322 — Safety Biomarker (SAF): Anti-BP180 autoantibody
Study NCT01662869 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01662869 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04001595 — Predictive Biomarker (PRD): FKRP mRNA
Genes: FKRP
Study NCT01016223 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01016223 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study NCT01016223 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT01016223 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01016223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00025909 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02478892 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02478892 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT03524417 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03897036 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study NCT06312033 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04337008 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04337008 — Surrogate Endpoint (SUR): Serum potassium
Study NCT03831646 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03831646 — Safety Biomarker (SAF): BDNF
Study NCT03831646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03831646 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02258997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04169126 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04355416 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00552409 — Surrogate Endpoint (SUR): Serum calcium
Study NCT00552409 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02331810 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT02331810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00235950 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02472665 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02472665 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT02671565 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02537145 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04912752 — Predictive Biomarker (PRD): CHRNA7 mRNA
Genes: CHRNA7; NACHRA7
Study NCT01722045 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04893889 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT00450424 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT02127177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01644188 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01644188 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04605198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01042717 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01042717 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02392663 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01882478 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study NCT02069600 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01181258 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01120990 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00000932 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01727531 — Predictive Biomarker (PRD): IDO2 mRNA
Genes: IDO2; INDOL1
Study NCT02624869 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02973802 — Predictive Biomarker (PRD): ENPP2 mRNA
Genes: ENPP2; ATX; PDNP2
Study NCT02973802 — Predictive Biomarker (PRD): TSHR mRNA
Genes: TSHR; LGR3
Study NCT02973802 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT03914677 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03713073 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT03487913 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT02633475 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01866709 — Surrogate Endpoint (SUR): Serum potassium
Study NCT03582696 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03227978 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02944539 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT03100110 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT01182012 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04070001 — Safety Biomarker (SAF): Interleukin 1
Study NCT03968952 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03877393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03877393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03877393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03877393 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study NCT02371174 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00997373 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00059904 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02147769 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02635997 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01665235 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00882011 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT03643523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03643523 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03643523 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02436512 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02239861 — Predictive Biomarker (PRD): MAGEA4 mRNA
Genes: MAGEA4; MAGE4
Study NCT02239861 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study NCT00016094 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03645200 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01665534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01665534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02158208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01516853 — Predictive Biomarker (PRD): Liver iron
Study NCT01417247 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00495872 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT06318065 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06318065 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT02625870 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT00769691 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01981681 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study NCT01064856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03028987 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00238459 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01283971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00996567 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00996567 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00003597 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03565692 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01746277 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01746277 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00061048 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT02544997 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02544997 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02544997 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03958708 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT03925688 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03847909 — Predictive Biomarker (PRD): PHC1 mRNA
Genes: PHC1; EDR1; PH1
Study NCT04294771 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04294771 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT00824772 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT00824772 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00824772 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT03820960 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT03345602 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT01836198 — Predictive Biomarker (PRD): CYP2J2 mRNA
Genes: CYP2J2
Study NCT01836198 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01667172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02437084 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04578223 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT02134145 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03481946 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study NCT04370379 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01693601 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT01587183 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00818441 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00950638 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT00950638 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03861000 — Predictive Biomarker (PRD): PDE4D mRNA
Genes: PDE4D; DPDE3
Study NCT02989285 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL