TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23703580 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 23703580 — Safety Biomarker (SAF): Interleukin 1
Study 23703580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23703723 — Surrogate Endpoint (SUR): Blood pressure
Study 23704672 — Surrogate Endpoint (SUR): Blood pressure
Study 23706709 — Predictive Biomarker (PRD): Interleukin 4 receptor alpha
Genes: IL4R; IL4RA; 582J2.1
Study 23707147 — Predictive Biomarker (PRD): ATXN1 mRNA
Genes: ATXN1; ATX1; SCA1
Study 23707147 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 23707147 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 23707169 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23707169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23707169 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 23714281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23715103 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 23715577 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 23715577 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 23716765 — Surrogate Endpoint (SUR): Blood pressure
Study 23719348 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23719719 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 23720182 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23721329 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23721329 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 23724914 — Predictive Biomarker (PRD): CD74 mRNA
Genes: CD74; DHLAG
Study 23724914 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 23724914 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 23726267 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23726267 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23726971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23728176 — Predictive Biomarker (PRD): ADAR mRNA
Genes: ADAR; ADAR1; DSRAD; G1P1; IFI4
Study 23728176 — Predictive Biomarker (PRD): DLK1 mRNA
Genes: DLK1; DLK
Study 23728176 — Predictive Biomarker (PRD): DIO3 mRNA
Genes: DIO3; ITDI3; TXDI3
Study 23728176 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 23728176 — Predictive Biomarker (PRD): miR-17
Genes: MIR17
Study 23730928 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 23731330 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 23731330 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23731760 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23731760 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 23731760 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23732043 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23733030 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 23733030 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23733030 — Predictive Biomarker (PRD): HTR1A mRNA
Genes: HTR1A; ADRB2RL1; ADRBRL1
Study 23733030 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 23733030 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 23733030 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 23733030 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 23733030 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 23733030 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 23733030 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 23733198 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 23733198 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23733198 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23733925 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 23735728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23735728 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23735728 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23738760 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23738760 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23739141 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 23740965 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23741398 — Predictive Biomarker (PRD): NBPF4 mRNA
Genes: NBPF4
Study 23741398 — Predictive Biomarker (PRD): CLCC1 mRNA
Genes: CLCC1; KIAA0761; MCLC
Study 23741398 — Predictive Biomarker (PRD): GPSM2 mRNA
Genes: GPSM2; LGN
Study 23741398 — Predictive Biomarker (PRD): PCDH17 mRNA
Genes: PCDH17; PCDH68; PCH68
Study 23744173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23745581 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23745581 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23748977 — Surrogate Endpoint (SUR): Blood pressure
Study 23750331 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23750331 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23751980 — Predictive Biomarker (PRD): NAAA mRNA
Genes: NAAA; ASAHL; PLT
Study 23752171 — Safety Biomarker (SAF): Interleukin 1
Study 23752175 — Predictive Biomarker (PRD): CDC25A mRNA
Genes: CDC25A
Study 23752175 — Predictive Biomarker (PRD): BRD4 mRNA
Genes: BRD4; HUNK1
Study 23752175 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 23753102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23753102 — Surrogate Endpoint (SUR): Blood pressure
Study 23754575 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 23754628 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23754628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23756334 — Surrogate Endpoint (SUR): Blood pressure
Study 23761092 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 23761401 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23761401 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 23761401 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 23761401 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23761422 — Predictive Biomarker (PRD): GRB10 mRNA
Genes: GRB10; GRBIR; KIAA0207
Study 23761422 — Predictive Biomarker (PRD): LHX4 mRNA
Genes: LHX4
Study 23761422 — Predictive Biomarker (PRD): PTPN1 mRNA
Genes: PTPN1; PTP1B
Study 23761422 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 23761422 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23761422 — Predictive Biomarker (PRD): MYOD1 mRNA
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 23764537 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 23764537 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 23765752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23765752 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 23770972 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 23773637 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23775962 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 23775962 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 23780948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23780948 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 23782158 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 23782157 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 23782682 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 23788609 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23788609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23788609 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23788609 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23791392 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23794578 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23794582 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 23796131 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23800144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23801633 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23809138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23809138 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23809138 — Safety Biomarker (SAF): Interleukin 1
Study 23809203 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 23809536 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23810300 — Predictive Biomarker (PRD): CDK7 mRNA
Genes: CDK7; CAK; CAK1; CDKN7; MO15; STK1
Study 23810467 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 23810467 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23810788 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 23810788 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23810788 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 23812932 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23813900 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23815472 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23815472 — Surrogate Endpoint (SUR): Serum creatinine
Study 23815876 — Predictive Biomarker (PRD): FOXP1 mRNA
Genes: FOXP1; HSPC215
Study 23815981 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 23816920 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 23816920 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 23816920 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 23816963 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23817974 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23817974 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23818490 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 23819769 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 23819769 — Surrogate Endpoint (SUR): Blood pressure
Study 23821658 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 23821658 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 23822537 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 23823198 — Safety Biomarker (SAF): IL16
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 23823198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23829205 — Surrogate Endpoint (SUR): Serum creatinine
Study 23829485 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 23831922 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 23831922 — Predictive Biomarker (PRD): MLLT10 mRNA
Genes: MLLT10; AF10
Study 23833039 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 23836798 — Surrogate Endpoint (SUR): Blood pressure
Study 23838996 — Predictive Biomarker (PRD): PDGFA mRNA
Genes: PDGFA; PDGF1
Study 23838996 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 23838996 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23839074 — Surrogate Endpoint (SUR): Blood pressure
Study 23839484 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 23840001 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 23840124 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 23840618 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23840618 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23842041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23844897 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23845948 — Predictive Biomarker (PRD): ARSA mRNA
Genes: ARSA
Study 23846249 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 23850394 — Surrogate Endpoint (SUR): Blood pressure
Study 23850901 — Surrogate Endpoint (SUR): Blood pressure
Study 23851911 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 23852419 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 23852775 — Predictive Biomarker (PRD): ZIC1 mRNA
Genes: ZIC1; ZIC; ZNF201
Study 23852775 — Predictive Biomarker (PRD): FOXG1 mRNA
Genes: FOXG1; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; FOXG1A; FOXG1B; FOXG1C
Study 23852775 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 23852775 — Predictive Biomarker (PRD): NFIA mRNA
Genes: NFIA; KIAA1439
Study 23855804 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23856024 — Predictive Biomarker (PRD): ABCA3 mRNA
Genes: ABCA3; ABC3
Study 23857966 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23860199 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 23860535 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23860535 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23861180 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 23861180 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23861247 — Predictive Biomarker (PRD): PDCD1 mRNA
Genes: PDCD1; PD1
Study 23861247 — Predictive Biomarker (PRD): CD160 mRNA
Genes: CD160; BY55
Study 23861247 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 23863898 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 23864214 — Surrogate Endpoint (SUR): Blood pressure
Study 23865516 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 23867552 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 23867552 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 23867552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 23867999 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23872309 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 23872309 — Predictive Biomarker (PRD): CARD6 mRNA
Genes: CARD6
Study 23872309 — Predictive Biomarker (PRD): CAP2 mRNA
Genes: CAP2
Study 23872668 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23872668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23873169 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 23874743 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23876210 — Monitoring Biomarker (MOI): HBV DNA
Study 23878115 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23878140 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 23878140 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 23878140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYH11 mRNA
Genes: MYH11; KIAA0866
Study 23878140 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 23878179 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23884778 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study 23884778 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 23884778 — Predictive Biomarker (PRD): PDHA1 mRNA
Genes: PDHA1; PHE1A
Study 23885047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23886346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23886346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23886346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23886346 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23886836 — Predictive Biomarker (PRD): ITK mRNA
Genes: ITK; EMT; LYK
Study 23886836 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 23887072 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 23887072 — Monitoring Biomarker (MOI): Cell-free DNA
Study 23887359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23887359 — Surrogate Endpoint (SUR): Serum uric acid
Study 23891891 — Safety Biomarker (SAF): IL16
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 23898383 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23899210 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 23899517 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23900696 — Surrogate Endpoint (SUR): Blood pressure
Study 23903897 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23904461 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 23904461 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study 23907406 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 23907406 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 23907406 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 23907471 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23907731 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23908489 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23911702 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 23911702 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 23911702 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 23912587 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23913461 — Surrogate Endpoint (SUR): Blood pressure
Study 23913470 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 23913470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23915500 — Predictive Biomarker (PRD): DLGAP2 mRNA
Genes: DLGAP2
Study 23917460 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 23917460 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23917460 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23917460 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 23922111 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23922111 — Predictive Biomarker (PRD): EGFL7 mRNA
Genes: EGFL7; MEGF7; UNQ187/PRO1449
Study 23922111 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23922302 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23922302 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 23929784 — Surrogate Endpoint (SUR): Bone mineral density
Study 23929784 — Surrogate Endpoint (SUR): Serum calcium
Study 23929927 — Surrogate Endpoint (SUR): Serum creatinine
Study 23929927 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23930209 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23930209 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 23930209 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 23930209 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 23930209 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 23932335 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23932335 — Predictive Biomarker (PRD): Hormone receptor
Study 23934126 — Predictive Biomarker (PRD): RTL1 mRNA
Genes: RTL1; MAR1; MART1; PEG11
Study 23936059 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study 23936059 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 23936565 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068