TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12502673 — Surrogate Endpoint (SUR): Blood pressure
Study 2321506 — Surrogate Endpoint (SUR): Blood pressure
Study 25522302 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 30893159 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 11056095 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8712118 — Surrogate Endpoint (SUR): Blood pressure
Study 8712118 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1827000 — Surrogate Endpoint (SUR): Blood pressure
Study 1827000 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24947112 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 22710369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22710369 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9715777 — Surrogate Endpoint (SUR): Blood pressure
Study 26223493 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 8380185 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 8380185 — Surrogate Endpoint (SUR): Blood pressure
Study 8380185 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3953429 — Surrogate Endpoint (SUR): Blood pressure
Study 27920513 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22618094 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 28668575 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 26714417 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26714417 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 18828959 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17007384 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17007384 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 17007384 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14508195 — Surrogate Endpoint (SUR): Blood pressure
Study 14508195 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 27378312 — Surrogate Endpoint (SUR): Blood pressure
Study 4028627 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22342390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22342390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22342390 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16705003 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 10882616 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8761371 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8694034 — Surrogate Endpoint (SUR): Bone mineral density
Study 8694034 — Surrogate Endpoint (SUR): Serum calcium
Study 26234526 — Surrogate Endpoint (SUR): Blood pressure
Study 30947915 — Surrogate Endpoint (SUR): Blood pressure
Study 21348810 — Surrogate Endpoint (SUR): Blood pressure
Study 14617264 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 14617264 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 21330902 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19815817 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 11977347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9447290 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 7523548 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31327563 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 22924607 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 26016510 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 20450723 — Surrogate Endpoint (SUR): Blood pressure
Study 20450723 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28391886 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28391886 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 28391886 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23065443 — Surrogate Endpoint (SUR): Blood pressure
Study 15827399 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 2371368 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 25112699 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 25112699 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 22229802 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9434661 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17876342 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 17876342 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 17876342 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 12575602 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 28531893 — Predictive Biomarker (PRD): HTR3A mRNA
Genes: HTR3A; 5HT3R; HTR3
Study 20108306 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 17697248 — Predictive Biomarker (PRD): KCNN3 mRNA
Genes: KCNN3; K3
Study 7485927 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 375435 — Surrogate Endpoint (SUR): Blood pressure
Study 28734853 — Surrogate Endpoint (SUR): Blood pressure
Study 23909490 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 23909490 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study 10543928 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12509376 — Surrogate Endpoint (SUR): Blood pressure
Study 31871108 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31871108 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 31871108 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 31871108 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 27140216 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24815795 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 11357167 — Safety Biomarker (SAF): Interleukin 1
Study 31160807 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 31160807 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 31023084 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31023084 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16381002 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 16381002 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 31553254 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25794236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25794236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22434756 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 22434756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28116886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28116886 — Surrogate Endpoint (SUR): Blood pressure
Study 22967997 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19272441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25592012 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 21924547 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 14974365 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14974365 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 14974365 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 14974365 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 14974365 — Surrogate Endpoint (SUR): Serum creatinine
Study 11045301 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9363911 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29203092 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29203092 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29203092 — Surrogate Endpoint (SUR): Serum creatinine
Study 29203092 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22892814 — Surrogate Endpoint (SUR): Blood pressure
Study 31988711 — Surrogate Endpoint (SUR): Blood pressure
Study 20528002 — Surrogate Endpoint (SUR): Blood pressure
Study 22286020 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24112026 — Predictive Biomarker (PRD): CD74 mRNA
Genes: CD74; DHLAG
Study 21613429 — Surrogate Endpoint (SUR): Blood pressure
Study 19918023 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 19918023 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7981558 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 18495465 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 7192456 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31647854 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 31647854 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24365793 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24365793 — Surrogate Endpoint (SUR): Serum creatinine
Study 11401008 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 9482137 — Surrogate Endpoint (SUR): Blood pressure
Study 4157346 — Surrogate Endpoint (SUR): Serum creatinine
Study 17170610 — Surrogate Endpoint (SUR): Blood pressure
Study 28736381 — Surrogate Endpoint (SUR): Blood pressure
Study 24827134 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24827134 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 22625844 — Surrogate Endpoint (SUR): Blood pressure
Study 19741011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17971594 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15378476 — Predictive Biomarker (PRD): Hormone receptor
Study 12932601 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26845191 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26845191 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8605127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27304975 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 20032281 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 12622859 — Safety Biomarker (SAF): Hyaluronic acid
Study 10638906 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6373155 — Surrogate Endpoint (SUR): Blood pressure
Study 10975216 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10975216 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 20303785 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21132065 — Surrogate Endpoint (SUR): Blood pressure
Study 1468291 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30911301 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24835324 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17938984 — Surrogate Endpoint (SUR): Bone mineral density
Study 7729606 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31358107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31358107 — Safety Biomarker (SAF): Interleukin 1
Study 18508120 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 20726909 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 9613225 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9613225 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 22578232 — Surrogate Endpoint (SUR): Blood pressure
Study 20929464 — Surrogate Endpoint (SUR): Blood pressure
Study 16204712 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17610024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17610024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 813120 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28711582 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 19779464 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 19779464 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 19779464 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 16450155 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16450155 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 16450155 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 8874308 — Surrogate Endpoint (SUR): Blood pressure
Study 8664131 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 1839902 — Surrogate Endpoint (SUR): Blood pressure
Study 24418244 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 22088518 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 22088518 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 17003569 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15259448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8471406 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8471406 — Surrogate Endpoint (SUR): Blood pressure
Study 2869849 — Surrogate Endpoint (SUR): Blood pressure
Study 30315150 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 23417688 — Surrogate Endpoint (SUR): Blood pressure
Study 20560730 — Surrogate Endpoint (SUR): Blood pressure
Study 18627322 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18627322 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10234895 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 30268865 — Surrogate Endpoint (SUR): Serum testosterone
Study 28198147 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19076137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11398518 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 26771632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22387276 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 22387276 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 7717564 — Surrogate Endpoint (SUR): Blood pressure
Study 14666758 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15215792 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16405436 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11471852 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11471852 — Surrogate Endpoint (SUR): Blood pressure
Study 9627123 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 18494215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18494215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26135463 — Surrogate Endpoint (SUR): Serum creatinine
Study 8467308 — Surrogate Endpoint (SUR): Blood pressure
Study 20436237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11801262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11801262 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21897852 — Surrogate Endpoint (SUR): Bone mineral density
Study 10436958 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10436958 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25604769 — Predictive Biomarker (PRD): C-C motif chemokine 7
Genes: CCL7; MCP3; SCYA6; SCYA7
Study 19332209 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19332209 — Surrogate Endpoint (SUR): Blood pressure
Study 16968790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11393553 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 26791478 — Surrogate Endpoint (SUR): Blood pressure
Study 24361280 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22620695 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17070596 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 10204726 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2676249 — Surrogate Endpoint (SUR): Blood pressure
Study 30335625 — Surrogate Endpoint (SUR): Blood pressure
Study 21546612 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 25962070 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2968267 — Surrogate Endpoint (SUR): Blood pressure
Study 30645203 — Pharmacodynamic Biomarker (PDY): C-type lectin domain family 4 member C
Genes: CLEC4C; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; UNQ9361/PRO34150
Study 22779380 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 17187606 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9831973 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9831973 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23785019 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 21083516 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 21083516 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17971525 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 11205424 — Surrogate Endpoint (SUR): Blood pressure
Study 20526530 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 16377282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14645783 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11314241 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 20378094 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 7852604 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 7852604 — Surrogate Endpoint (SUR): Blood pressure
Study 2903727 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2903727 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 8514071 — Surrogate Endpoint (SUR): Blood pressure
Study 26523663 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 23635998 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17198774 — Safety Biomarker (SAF): Reactive oxygen species
Study 17198774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26108190 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 9587116 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 7821189 — Safety Biomarker (SAF): 51Cr-EDTA
Study 28747245 — Surrogate Endpoint (SUR): Blood pressure
Study 21121958 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18032219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15617459 — Surrogate Endpoint (SUR): Blood pressure
Study 30232857 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30232857 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30232857 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26229089 — Surrogate Endpoint (SUR): Blood pressure
Study 26229089 — Surrogate Endpoint (SUR): Serum creatinine
Study 19508966 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 16118673 — Monitoring Biomarker (MOI): HBV DNA
Study 10519562 — Predictive Biomarker (PRD): DRAM1 mRNA
Genes: DRAM1; DRAM
Study 10519562 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 30100106 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 18727459 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20952427 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7661492 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8023538 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 16771869 — Surrogate Endpoint (SUR): Serum creatinine
Study 15090835 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9428939 — Surrogate Endpoint (SUR): Blood pressure
Study 29223745 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29223745 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 29223745 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29223745 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 29223745 — Predictive Biomarker (PRD): Hormone receptor
Study 1536412 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27296860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24841327 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 24841327 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11783223 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 25142778 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25142778 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19243886 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA