TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18427279 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 1854570 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26956618 — Surrogate Endpoint (SUR): Bone mineral density
Study 29258763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18349060 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1540362 — Surrogate Endpoint (SUR): Blood pressure
Study 20078609 — Surrogate Endpoint (SUR): Blood pressure
Study 17686882 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31837988 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28453843 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28453843 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28453843 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 28453843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28453843 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28453843 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17460329 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 31606815 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 30602311 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24081023 — Surrogate Endpoint (SUR): Bone mineral density
Study 24081023 — Surrogate Endpoint (SUR): Serum calcium
Study 19122354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12364431 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11333010 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11333010 — Surrogate Endpoint (SUR): Blood pressure
Study 30648598 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30648598 — Surrogate Endpoint (SUR): Blood pressure
Study 25332249 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17376268 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2149688 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28553847 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22940818 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 19237568 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7524159 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21762357 — Surrogate Endpoint (SUR): Blood pressure
Study 19092234 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10818025 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26437712 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 17590156 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 17590156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10412726 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10412726 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7032811 — Surrogate Endpoint (SUR): Blood pressure
Study 6704545 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 23416308 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 21135022 — Safety Biomarker (SAF): Interleukin 12
Study 15329205 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 15329205 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 15329205 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 15329205 — Safety Biomarker (SAF): Hyaluronic acid
Study 25567150 — Surrogate Endpoint (SUR): Blood pressure
Study 15340532 — Monitoring Biomarker (MOI): HBV DNA
Study 11589607 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9598254 — Surrogate Endpoint (SUR): Blood pressure
Study 7834990 — Surrogate Endpoint (SUR): Blood pressure
Study 3165298 — Surrogate Endpoint (SUR): Hematologic response
Study 23485864 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 23485864 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 21428766 — Surrogate Endpoint (SUR): Blood pressure
Study 21428766 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23871267 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 12962750 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 23009891 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23009891 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18006170 — Surrogate Endpoint (SUR): Blood pressure
Study 9345434 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1675763 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7148732 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28457217 — Surrogate Endpoint (SUR): Serum calcium
Study 22383996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17463140 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 17463140 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17463140 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 17463140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30955400 — Surrogate Endpoint (SUR): Blood pressure
Study 30517599 — Surrogate Endpoint (SUR): Blood pressure
Study 21779873 — Predictive Biomarker (PRD): SLC30A8 mRNA
Genes: SLC30A8; ZNT8
Study 9805693 — Surrogate Endpoint (SUR): Serum creatinine
Study 7112396 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 30522922 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 18003042 — Surrogate Endpoint (SUR): Blood pressure
Study 16117818 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 16117818 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12191566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29870855 — Monitoring Biomarker (MOI): Procalcitonin
Study 29870855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24623067 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19074534 — Surrogate Endpoint (SUR): Blood pressure
Study 15124006 — Predictive Biomarker (PRD): TPH2 mRNA
Genes: TPH2; NTPH
Study 12235444 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 7859051 — Surrogate Endpoint (SUR): Blood pressure
Study 7859051 — Surrogate Endpoint (SUR): Serum potassium
Study 2698934 — Surrogate Endpoint (SUR): Blood pressure
Study 28034079 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28034079 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17290039 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17290039 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 8896396 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8896396 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 8896396 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31093657 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 25179916 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 17062764 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 17062764 — Predictive Biomarker (PRD): PDK2 mRNA
Genes: PDK2; PDHK2
Study 7925518 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7925518 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2511299 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30591410 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 25561281 — Monitoring Biomarker (MOI): Procalcitonin
Study 25561281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16508590 — Surrogate Endpoint (SUR): Blood pressure
Study 31785994 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 31785994 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 24312194 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20167684 — Surrogate Endpoint (SUR): Blood pressure
Study 10535703 — Surrogate Endpoint (SUR): Blood pressure
Study 8561070 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8561070 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6125188 — Surrogate Endpoint (SUR): Blood pressure
Study 19008724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30834812 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 29423521 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29423521 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29423521 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 26813548 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26813548 — Surrogate Endpoint (SUR): Blood pressure
Study 21059972 — Surrogate Endpoint (SUR): Blood pressure
Study 21059972 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18925883 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16687966 — Surrogate Endpoint (SUR): Blood pressure
Study 3490176 — Surrogate Endpoint (SUR): Serum calcium
Study 3490176 — Surrogate Endpoint (SUR): Blood pressure
Study 24438094 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24438094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24438094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22722501 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30001547 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 20403483 — Predictive Biomarker (PRD): KIF6 mRNA
Genes: KIF6; C6orf102
Study 10380089 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31997084 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 15257733 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8608073 — Surrogate Endpoint (SUR): Blood pressure
Study 25490675 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25490675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17686832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17686832 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17686832 — Surrogate Endpoint (SUR): Blood pressure
Study 31358032 — Monitoring Biomarker (MOI): Procalcitonin
Study 28099485 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 24026560 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24026560 — Surrogate Endpoint (SUR): Blood pressure
Study 8799530 — Predictive Biomarker (PRD): MPZ mRNA
Genes: MPZ
Study 1600971 — Surrogate Endpoint (SUR): Blood pressure
Study 2858186 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 31466813 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25171552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 10962867 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6725527 — Surrogate Endpoint (SUR): Blood pressure
Study 10548188 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 10548188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10548188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8517061 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 3481814 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 3481814 — Surrogate Endpoint (SUR): Blood pressure
Study 31736269 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 31736269 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 31736269 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31736269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 31736269 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29164797 — Surrogate Endpoint (SUR): Blood pressure
Study 25618791 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25618791 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21511212 — Surrogate Endpoint (SUR): Blood pressure
Study 16935343 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15293170 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 8004320 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21505349 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21505349 — Surrogate Endpoint (SUR): Blood pressure
Study 9113009 — Surrogate Endpoint (SUR): Blood pressure
Study 20929598 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18356628 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18356628 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18356628 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10337457 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9110055 — Surrogate Endpoint (SUR): Blood pressure
Study 31348336 — Safety Biomarker (SAF): Hyaluronic acid
Study 19478258 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19478258 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 6138935 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16369229 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29909057 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26879693 — Surrogate Endpoint (SUR): Blood pressure
Study 23292523 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12701995 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8864022 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8864022 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 31111436 — Surrogate Endpoint (SUR): Bone mineral density
Study 25835231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17521930 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9531962 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 4413307 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 30991614 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11485511 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9926277 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28238190 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 23259919 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21450590 — Surrogate Endpoint (SUR): Blood pressure
Study 11916767 — Surrogate Endpoint (SUR): Bone mineral density
Study 17053536 — Surrogate Endpoint (SUR): Blood pressure
Study 17053536 — Surrogate Endpoint (SUR): Serum creatinine
Study 14521705 — Surrogate Endpoint (SUR): Serum calcium
Study 14521705 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 10930152 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27379388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10599726 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 30380116 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30380116 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 9571349 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9571349 — Surrogate Endpoint (SUR): Blood pressure
Study 9571349 — Surrogate Endpoint (SUR): Serum creatinine
Study 2907520 — Surrogate Endpoint (SUR): Blood pressure
Study 31084315 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 23278295 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23278295 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 19623014 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 31792304 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31792304 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31792304 — Predictive Biomarker (PRD): Hormone receptor
Study 30217193 — Surrogate Endpoint (SUR): Blood pressure
Study 22610153 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22610153 — Predictive Biomarker (PRD): Hormone receptor
Study 17197223 — Surrogate Endpoint (SUR): Bone mineral density
Study 15572415 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 15572415 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30990260 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 30990260 — Surrogate Endpoint (SUR): Serum creatinine
Study 26002686 — Surrogate Endpoint (SUR): Blood pressure
Study 23795805 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 24751432 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 20056760 — Surrogate Endpoint (SUR): Serum calcium
Study 17107982 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 15462191 — Predictive Biomarker (PRD): DMPK mRNA
Genes: DMPK; DM1PK; MDPK
Study 29575526 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 16799983 — Monitoring Biomarker (MOI): HBV DNA
Study 31987113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31987113 — Surrogate Endpoint (SUR): Blood pressure
Study 11673338 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29021336 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26843962 — Surrogate Endpoint (SUR): Blood pressure
Study 26843962 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17313271 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9741406 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 15569840 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15569840 — Surrogate Endpoint (SUR): Serum creatinine
Study 23263240 — Surrogate Endpoint (SUR): Blood pressure
Study 15069400 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8485014 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3732372 — Surrogate Endpoint (SUR): Blood pressure
Study 18394319 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 16170294 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 22586106 — Predictive Biomarker (PRD): PRKCA mRNA
Genes: PRKCA; PKCA; PRKACA
Study 10469748 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 27612466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25395210 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 24421054 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24421054 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15282117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15282117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12642692 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24326597 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15206993 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8619366 — Surrogate Endpoint (SUR): Bone mineral density
Study 28118281 — Surrogate Endpoint (SUR): Blood pressure
Study 21864816 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 18988892 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17943569 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 29164723 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 12748212 — Surrogate Endpoint (SUR): Blood pressure
Study 8820427 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 1602035 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2102130 — Surrogate Endpoint (SUR): Blood pressure
Study 25652112 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9509447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15848545 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 15848545 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 21219598 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 21219598 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 15577128 — Surrogate Endpoint (SUR): Bone mineral density