TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27742728 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17716953 — Surrogate Endpoint (SUR): Blood pressure
Study 8860007 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 31058762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27251974 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 21053621 — Surrogate Endpoint (SUR): Blood pressure
Study 15848571 — Surrogate Endpoint (SUR): Blood pressure
Study 15848571 — Surrogate Endpoint (SUR): Serum creatinine
Study 9620309 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29051306 — Surrogate Endpoint (SUR): Blood pressure
Study 14739801 — Safety Biomarker (SAF): 51Cr-EDTA
Study 14739801 — Surrogate Endpoint (SUR): Blood pressure
Study 3150824 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 28816509 — Surrogate Endpoint (SUR): Blood pressure
Study 7748214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7748214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7748214 — Safety Biomarker (SAF): Interleukin 1
Study 24218952 — Surrogate Endpoint (SUR): Serum testosterone
Study 11460891 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 30527263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30527263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22728482 — Monitoring Biomarker (MOI): HBV DNA
Study 19941906 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19941906 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 2280233 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2280233 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27055960 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27055960 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27055960 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20845101 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20845101 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12573788 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 2000792 — Surrogate Endpoint (SUR): Blood pressure
Study 2000792 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2000792 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26137952 — Surrogate Endpoint (SUR): Blood pressure
Study 28421240 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26136593 — Surrogate Endpoint (SUR): Blood pressure
Study 26136593 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11834646 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7618675 — Surrogate Endpoint (SUR): Blood pressure
Study 17308528 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17308528 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15179180 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15179180 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17059015 — Monitoring Biomarker (MOI): HBV DNA
Study 15546231 — Surrogate Endpoint (SUR): Blood pressure
Study 3295034 — Surrogate Endpoint (SUR): Blood pressure
Study 31618456 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26572609 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 31951771 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 29354930 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29354930 — Surrogate Endpoint (SUR): Blood pressure
Study 29354930 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29354930 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29354930 — Surrogate Endpoint (SUR): Serum creatinine
Study 27631719 — Surrogate Endpoint (SUR): Blood pressure
Study 26586732 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 26586732 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23444204 — Safety Biomarker (SAF): Hyaluronic acid
Study 2081608 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25123170 — Surrogate Endpoint (SUR): Blood pressure
Study 18688814 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 18688814 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18688814 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3559982 — Surrogate Endpoint (SUR): Blood pressure
Study 20102300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15914552 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2650734 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2650734 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2650734 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26282654 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study 26282654 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26282654 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 26282654 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 26282654 — Predictive Biomarker (PRD): H1-4 mRNA
Genes: H1-4; H1F4; HIST1H1E
Study 26282654 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 26282654 — Predictive Biomarker (PRD); Safety Biomarker (SAF): EGR1 mRNA
Genes: EGR1; KROX24; ZNF225
Study 26282654 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 26282654 — Predictive Biomarker (PRD): TRAF3 mRNA
Genes: TRAF3; CAP-1; CRAF1; TRAFAMN
Study 26282654 — Predictive Biomarker (PRD): TENT5C mRNA
Genes: TENT5C; FAM46C
Study 26282654 — Predictive Biomarker (PRD): DIS3 mRNA
Genes: DIS3; KIAA1008; RRP44
Study 23692303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20562170 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 9538975 — Surrogate Endpoint (SUR): Blood pressure
Study 4558903 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11929404 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7978397 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28449690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20021666 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 11265776 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27146814 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 19702471 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 2507321 — Surrogate Endpoint (SUR): Blood pressure
Study 45463 — Surrogate Endpoint (SUR): Blood pressure
Study 31302338 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23280225 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21056418 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 21056418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17073812 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8336224 — Surrogate Endpoint (SUR): Serum potassium
Study 8336224 — Surrogate Endpoint (SUR): Serum sodium
Study 26928670 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26928670 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26928670 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24572997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20306554 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26474541 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11374763 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8060581 — Surrogate Endpoint (SUR): Blood pressure
Study 15242697 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 15242697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15242697 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 11095487 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 11095487 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9050018 — Surrogate Endpoint (SUR): Blood pressure
Study 24292894 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 20637377 — Monitoring Biomarker (MOI): Procalcitonin
Study 16703004 — Surrogate Endpoint (SUR): Blood pressure
Study 31331574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17152004 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25362864 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25692840 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17456124 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 15081625 — Surrogate Endpoint (SUR): Blood pressure
Study 2559485 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29195999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29195999 — Surrogate Endpoint (SUR): Blood pressure
Study 29195999 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 25520280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25520280 — Safety Biomarker (SAF): IL-6 and IL-10
Study 9002079 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8240880 — Surrogate Endpoint (SUR): Blood pressure
Study 27017611 — Surrogate Endpoint (SUR): Serum uric acid
Study 31641325 — Surrogate Endpoint (SUR): Blood pressure
Study 22359978 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 22359978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11329232 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11329232 — Surrogate Endpoint (SUR): Hematologic response
Study 29216947 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16758078 — Surrogate Endpoint (SUR): Blood pressure
Study 8390795 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27051354 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 23824870 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 22566583 — Surrogate Endpoint (SUR): Blood pressure
Study 22566583 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16631259 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study 8741040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29048765 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29048765 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24439313 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22625863 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 13680141 — Surrogate Endpoint (SUR): Bone mineral density
Study 7596131 — Surrogate Endpoint (SUR): Blood pressure
Study 28656353 — Surrogate Endpoint (SUR): Blood pressure
Study 23926207 — Surrogate Endpoint (SUR): Blood pressure
Study 20455192 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28752433 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25252663 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 22980174 — Predictive Biomarker (PRD): KCNN3 mRNA
Genes: KCNN3; K3
Study 3519043 — Surrogate Endpoint (SUR): Blood pressure
Study 24603938 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24603938 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22027793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22027793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22027793 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10962123 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 22284900 — Surrogate Endpoint (SUR): Blood pressure
Study 12944692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12944692 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 6628500 — Surrogate Endpoint (SUR): Blood pressure
Study 15536455 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 15536455 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 15536455 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2756914 — Surrogate Endpoint (SUR): Blood pressure
Study 2756914 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28674135 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 15021967 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9784903 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9784903 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9784903 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 7609494 — Surrogate Endpoint (SUR): Blood pressure
Study 7609494 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21849660 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20439556 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20439556 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17225981 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17225981 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23047989 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15010373 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17097955 — Surrogate Endpoint (SUR): Blood pressure
Study 17097955 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17097955 — Surrogate Endpoint (SUR): Serum potassium
Study 9578508 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 3376143 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 23948125 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17023701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8719186 — Surrogate Endpoint (SUR): Blood pressure
Study 31055791 — Surrogate Endpoint (SUR): Serum creatinine
Study 28950421 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 28950421 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 26083426 — Surrogate Endpoint (SUR): Blood pressure
Study 24021938 — Surrogate Endpoint (SUR): Blood pressure
Study 28209359 — Surrogate Endpoint (SUR): Blood pressure
Study 23911216 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21527854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21527854 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 18854397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3529744 — Surrogate Endpoint (SUR): Serum creatinine
Study 12208703 — Predictive Biomarker (PRD): ALPI mRNA
Genes: ALPI
Study 8676932 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6175137 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 28186425 — Surrogate Endpoint (SUR): Blood pressure
Study 19571807 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 19571807 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 12209278 — Surrogate Endpoint (SUR): Blood pressure
Study 24780066 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9819068 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 19593890 — Surrogate Endpoint (SUR): Blood pressure
Study 9456291 — Surrogate Endpoint (SUR): Blood pressure
Study 11868797 — Surrogate Endpoint (SUR): Blood pressure
Study 7639971 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 951455 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 30668163 — Surrogate Endpoint (SUR): Blood pressure
Study 25565656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17182977 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9682660 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 23043888 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18234290 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 3953366 — Surrogate Endpoint (SUR): Blood pressure
Study 22508151 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18789113 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16125959 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10091821 — Surrogate Endpoint (SUR): Blood pressure
Study 7772081 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7438772 — Surrogate Endpoint (SUR): Blood pressure
Study 31910903 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 30991661 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 14706480 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31167421 — Surrogate Endpoint (SUR): Blood pressure
Study 15156528 — Surrogate Endpoint (SUR): Blood pressure
Study 9386869 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26282650 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 12723391 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27513932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27513932 — Surrogate Endpoint (SUR): Blood pressure
Study 18549857 — Surrogate Endpoint (SUR): Blood pressure
Study 12806595 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25243781 — Surrogate Endpoint (SUR): Blood pressure
Study 25157406 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18688657 — Surrogate Endpoint (SUR): Blood pressure
Study 24934915 — Safety Biomarker (SAF): Hyaluronic acid
Study 19602610 — Surrogate Endpoint (SUR): Blood pressure
Study 9645291 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9645291 — Surrogate Endpoint (SUR): Blood pressure
Study 29615070 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 29615070 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1969252 — Surrogate Endpoint (SUR): Blood pressure
Study 31664444 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 29966992 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 20876408 — Surrogate Endpoint (SUR): Blood pressure
Study 20876408 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20876408 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11932285 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2692825 — Surrogate Endpoint (SUR): Blood pressure
Study 12684211 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9190129 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3590805 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25042022 — Surrogate Endpoint (SUR): Blood pressure
Study 25042022 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31344077 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7924704 — Predictive Biomarker (PRD): MN1 mRNA
Genes: MN1
Study 23104720 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17140167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17140167 — Surrogate Endpoint (SUR): Serum creatinine
Study 10771457 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 1425625 — Surrogate Endpoint (SUR): Blood pressure
Study 26702788 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 23029839 — Surrogate Endpoint (SUR): Blood pressure
Study 20102879 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12668861 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 7649753 — Surrogate Endpoint (SUR): Blood pressure
Study 25557052 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11141242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11141242 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 11141242 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20216098 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 20216098 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 20216098 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20216098 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 18594529 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10421591 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 15043519 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9493701 — Surrogate Endpoint (SUR): Blood pressure
Study 26668200 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22055112 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 17452287 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 15561950 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67