TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19616494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14991243 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 23744766 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 23744766 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 9192511 — Surrogate Endpoint (SUR): Bone mineral density
Study 15231982 — Surrogate Endpoint (SUR): Serum creatinine
Study 11807721 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 11807721 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 11807721 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 25849853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25849853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25849853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21546089 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21546089 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28291675 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 18708687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18708687 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16443353 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 1831005 — Surrogate Endpoint (SUR): Blood pressure
Study 24216182 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 11103296 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 27181507 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 12646342 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12646342 — Surrogate Endpoint (SUR): Blood pressure
Study 19040016 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 12679767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12679767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12679767 — Safety Biomarker (SAF): Interleukin 1
Study 12679767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29447199 — Safety Biomarker (SAF): IL-6 and IL-10
Study 2181769 — Surrogate Endpoint (SUR): Serum sodium
Study 383033 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 383033 — Surrogate Endpoint (SUR): Blood pressure
Study 28939642 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 28939642 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28939642 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23571650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23571650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23571650 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19454869 — Surrogate Endpoint (SUR): Blood pressure
Study 29923427 — Surrogate Endpoint (SUR): Blood pressure
Study 26851146 — Surrogate Endpoint (SUR): Serum sodium
Study 26851146 — Surrogate Endpoint (SUR): Blood pressure
Study 31570733 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31570733 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23645099 — Surrogate Endpoint (SUR): Blood pressure
Study 17257991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17257991 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17257991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17257991 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 17257991 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17257991 — Safety Biomarker (SAF): Interleukin 1
Study 26653189 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 11326179 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 11326179 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30678863 — Surrogate Endpoint (SUR): Blood pressure
Study 27043452 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 2144154 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23615650 — Surrogate Endpoint (SUR): Blood pressure
Study 17130197 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12601628 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7074797 — Surrogate Endpoint (SUR): Blood pressure
Study 26419215 — Surrogate Endpoint (SUR): Blood pressure
Study 21554817 — Surrogate Endpoint (SUR): Blood pressure
Study 14714091 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 14714091 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 2826067 — Surrogate Endpoint (SUR): Blood pressure
Study 27710149 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27710149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 16376979 — Surrogate Endpoint (SUR): Blood pressure
Study 7605361 — Surrogate Endpoint (SUR): Blood pressure
Study 2357777 — Surrogate Endpoint (SUR): Serum potassium
Study 22283635 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19019257 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 19019257 — Predictive Biomarker (PRD): ABCG8 mRNA
Genes: ABCG8
Study 16405839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16405839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16405839 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12021824 — Surrogate Endpoint (SUR): Blood pressure
Study 2080308 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 30590857 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 17255371 — Surrogate Endpoint (SUR): Blood pressure
Study 15371667 — Surrogate Endpoint (SUR): Serum creatinine
Study 18278183 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26486704 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16529046 — Surrogate Endpoint (SUR): Pathological complete response
Study 11768726 — Surrogate Endpoint (SUR): Blood pressure
Study 31506877 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31506877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29231549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23549132 — Surrogate Endpoint (SUR): Blood pressure
Study 18505968 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18505968 — Predictive Biomarker (PRD): Hormone receptor
Study 17160915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17160915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24401754 — Surrogate Endpoint (SUR): Serum calcium
Study 9527749 — Surrogate Endpoint (SUR): Blood pressure
Study 2673080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28698476 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 24105072 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 3283766 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 3283766 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26858013 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23327968 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10632776 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 27026311 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 23825002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23825002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16139580 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 23326865 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2903191 — Surrogate Endpoint (SUR): Blood pressure
Study 21112101 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 19531453 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23878368 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23878368 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20808146 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 26892991 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12756402 — Surrogate Endpoint (SUR): Blood pressure
Study 27221806 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24299915 — Surrogate Endpoint (SUR): Blood pressure
Study 20812339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20812339 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20812339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7581055 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study 10651841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22211699 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 3332575 — Surrogate Endpoint (SUR): Blood pressure
Study 26305413 — Predictive Biomarker (PRD): NPW mRNA
Genes: NPW; PPL8; PPNPW
Study 22051697 — Predictive Biomarker (PRD): CRTAM mRNA
Genes: CRTAM
Study 10102158 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 24734908 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 15001199 — Surrogate Endpoint (SUR): Blood pressure
Study 3298936 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27848149 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 21516302 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21516302 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10757623 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28323043 — Surrogate Endpoint (SUR): Bone mineral density
Study 23107894 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23107894 — Surrogate Endpoint (SUR): Blood pressure
Study 19295224 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 11792769 — Predictive Biomarker (PRD): ST3GAL4 mRNA
Genes: ST3GAL4; CGS23; NANTA3; SIAT4C; STZ
Study 11792769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7594424 — Surrogate Endpoint (SUR): Blood pressure
Study 7594424 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1724914 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29523624 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20813689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20813689 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15144909 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15144909 — Surrogate Endpoint (SUR): Blood pressure
Study 2883952 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29731444 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29731444 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16236684 — Surrogate Endpoint (SUR): Blood pressure
Study 12837043 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12837043 — Surrogate Endpoint (SUR): Blood pressure
Study 9694052 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9694052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9694052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9694052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8081529 — Surrogate Endpoint (SUR): Blood pressure
Study 4552591 — Surrogate Endpoint (SUR): Blood pressure
Study 28968163 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28968163 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28968163 — Predictive Biomarker (PRD): Hormone receptor
Study 10449888 — Surrogate Endpoint (SUR): Blood pressure
Study 30956267 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24010992 — Surrogate Endpoint (SUR): Bone mineral density
Study 18257347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18257347 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18257347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30095354 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30095354 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 17438101 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 17438101 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17438101 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17438101 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17438101 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17438101 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17438101 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 2843341 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2843341 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31635497 — Predictive Biomarker (PRD): SERPING1 mRNA
Genes: SERPING1; C1IN; C1NH
Study 23291612 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study 23291612 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 23291612 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23291612 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 9082864 — Surrogate Endpoint (SUR): Blood pressure
Study 16403712 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 14634680 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 21441812 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 15513446 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28271568 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28271568 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18931625 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16820341 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 16820341 — Surrogate Endpoint (SUR): Blood pressure
Study 21557134 — Surrogate Endpoint (SUR): Bone mineral density
Study 10964582 — Surrogate Endpoint (SUR): Serum creatinine
Study 8619212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8619212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3872001 — Surrogate Endpoint (SUR): Blood pressure
Study 22929437 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study 20059663 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 15470483 — Surrogate Endpoint (SUR): Blood pressure
Study 11824861 — Surrogate Endpoint (SUR): Blood pressure
Study 8618108 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26044854 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 26044854 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 17925592 — Surrogate Endpoint (SUR): Blood pressure
Study 10728939 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 2027357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6161557 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21505892 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 12920975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12920975 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12920975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7498858 — Surrogate Endpoint (SUR): Blood pressure
Study 26809868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23244537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23244537 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17932317 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28851407 — Surrogate Endpoint (SUR): Blood pressure
Study 22021620 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11733695 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 24548574 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24548574 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21801467 — Surrogate Endpoint (SUR): Blood pressure
Study 8671790 — Surrogate Endpoint (SUR): Blood pressure
Study 17469154 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7827929 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7827929 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23315144 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23315144 — Surrogate Endpoint (SUR): Bone mineral density
Study 19724980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11822785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31891746 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31891746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 31891746 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31220630 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 31679055 — Surrogate Endpoint (SUR): Bone mineral density
Study 21748205 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16951472 — Surrogate Endpoint (SUR): Bone mineral density
Study 12730811 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8952125 — Surrogate Endpoint (SUR): Blood pressure
Study 2009249 — Surrogate Endpoint (SUR): Blood pressure
Study 31732852 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28248037 — Safety Biomarker (SAF): Reactive oxygen species
Study 16878325 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 16878325 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 16878325 — Predictive Biomarker (PRD): CLEC4D mRNA
Genes: CLEC4D; CLECSF8; MCL
Study 16878325 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 29135482 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26684822 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10652036 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10652036 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10652036 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10652036 — Surrogate Endpoint (SUR): Blood pressure
Study 25220196 — Surrogate Endpoint (SUR): Bone mineral density
Study 7305656 — Surrogate Endpoint (SUR): Blood pressure
Study 28975661 — Surrogate Endpoint (SUR): Bone mineral density
Study 25380675 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25380675 — Safety Biomarker (SAF): Reactive oxygen species
Study 8947787 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20391513 — Surrogate Endpoint (SUR): Bone mineral density
Study 2166253 — Surrogate Endpoint (SUR): Blood pressure
Study 10372612 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell