TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04290182 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00701987 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03728049 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00826514 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04247048 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02727543 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00283387 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT02725502 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00089674 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01818544 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01818544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02974595 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study NCT02974595 — Predictive Biomarker (PRD): NLRC4 mRNA
Genes: NLRC4; CARD12; CLAN; CLAN1; IPAF; UNQ6189/PRO20215
Study NCT00903578 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03751306 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study NCT03751306 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01113541 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01113541 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01176357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01176357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01176357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02447783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00650923 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02489370 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01583270 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03924843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03924843 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT03668028 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT02309463 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00048087 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00048087 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01458951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03482895 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02378805 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00593138 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT01326000 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03584009 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03584009 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03584009 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01206712 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03222492 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT01123434 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT02496260 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02758587 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT02758587 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02013219 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02013219 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02013219 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00235001 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00089635 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00977080 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT03964337 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT04460430 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04460430 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04460430 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04460430 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04460430 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01588821 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02914366 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT03112811 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04510220 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT04510220 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01002157 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT03558997 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT01815411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01815411 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02065791 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02065791 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01951547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01951547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00131196 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study NCT00131196 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT00076323 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT02683187 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02687269 — Predictive Biomarker (PRD): INA mRNA
Genes: INA; NEF5
Study NCT00525031 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT04260932 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02485938 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02729194 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02729194 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04077463 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04077463 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04077463 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00581373 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01656954 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00668005 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04299529 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04324398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02368691 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04392986 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03357939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00125034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00125034 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00125034 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02956811 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01551940 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study NCT02655601 — Predictive Biomarker (PRD): BMX mRNA
Genes: BMX
Study NCT00216034 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01071109 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study NCT01071109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01071109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04280848 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT04280848 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02323295 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02323295 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT05072405 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study NCT05072405 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study NCT01372826 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT00613626 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01044355 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02312687 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02312687 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study NCT02312687 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT02312687 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT01874990 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02709798 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT00688207 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01728233 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01728233 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01086280 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03577132 — Predictive Biomarker (PRD): KRT5 mRNA
Genes: KRT5
Study NCT03577132 — Predictive Biomarker (PRD): KRT14 mRNA
Genes: KRT14
Study NCT03577132 — Predictive Biomarker (PRD): FOXA1 mRNA
Genes: FOXA1; HNF3A; TCF3A
Study NCT03577132 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study NCT01655134 — Surrogate Endpoint (SUR): Serum potassium
Study NCT01655134 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01224210 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT01224210 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03577990 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00877838 — Predictive Biomarker (PRD): NXN mRNA
Genes: NXN; NRX
Study NCT01663441 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study NCT00931567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00931567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00931567 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study NCT00931567 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03920072 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01392521 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02714764 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT02891616 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01918111 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02022176 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01916395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01916395 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT04270669 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04497974 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01346800 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01346800 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01346800 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01346800 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT01346800 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03633708 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT04002804 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03118479 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study NCT00048893 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00048893 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03362476 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04513158 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00685087 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT01614379 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00600561 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01782352 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02868398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00005705 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study NCT04104594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04865848 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00000158 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03101072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01715844 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01179282 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT00468715 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00468715 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00903734 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00903734 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02976506 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03083054 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT02278887 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05099029 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02101437 — Safety Biomarker (SAF): miR-96
Genes: MIR96
Study NCT03658889 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study NCT03826888 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02748005 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT03489577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02439528 — Predictive Biomarker (PRD): SFTPC mRNA
Genes: SFTPC; SFTP2
Study NCT02439528 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT03685448 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00561483 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT00561483 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02568267 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT02568267 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT02568267 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00830518 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT01290497 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01200394 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01575743 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03996967 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT03996967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01632943 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03678714 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05514743 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00618774 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00740467 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT02370316 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01245517 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT01245517 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04394247 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04394247 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03804801 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03263819 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02383030 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04246502 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04787861 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02236754 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study NCT01548625 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study NCT01548625 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02981576 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04674943 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02741362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02741362 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT02741362 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02741362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02741362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02741362 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT02833857 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT01479855 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01479855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02856867 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02580019 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03771378 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT02626065 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04125745 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01266720 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01266720 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01266720 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT02457715 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT04532411 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00729222 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02047240 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT00613314 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03361501 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01047969 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT03397108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03023748 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT00667030 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02760251 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT03758417 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03953378 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study NCT01955460 — Predictive Biomarker (PRD): NGFR mRNA
Genes: NGFR; TNFRSF16
Study NCT01955460 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01955460 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01142154 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT01952028 — Predictive Biomarker (PRD): LAMA2 mRNA
Genes: LAMA2; LAMM
Study NCT00442598 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT04076826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04076826 — Safety Biomarker (SAF): Interleukin 1
Study NCT04076826 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study NCT04076826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03705169 — Surrogate Endpoint (SUR): Neutralizing antibody