TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15168040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11248360 — Monitoring Biomarker (MOI): HBV DNA
Study 7585753 — Surrogate Endpoint (SUR): Blood pressure
Study 25823991 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21151012 — Surrogate Endpoint (SUR): Blood pressure
Study 7838916 — Safety Biomarker (SAF): DRD2
Study 28720079 — Surrogate Endpoint (SUR): Blood pressure
Study 26174719 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 26174719 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 26174719 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 9142590 — Surrogate Endpoint (SUR): Blood pressure
Study 31783127 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 17190414 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 14708047 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 14708047 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 14708047 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 14708047 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 14708047 — Predictive Biomarker (PRD): Microsatellite instability
Study 29299989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28892496 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 25809413 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 25809413 — Surrogate Endpoint (SUR): Blood pressure
Study 23496265 — Surrogate Endpoint (SUR): Blood pressure
Study 20833549 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study 10728742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3158674 — Surrogate Endpoint (SUR): Blood pressure
Study 29333721 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 12502672 — Surrogate Endpoint (SUR): Blood pressure
Study 19270469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19270469 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2530384 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29346597 — Safety Biomarker (SAF): Interleukin 1
Study 29346597 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 24290606 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23662522 — Surrogate Endpoint (SUR): Blood pressure
Study 15989703 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11875707 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 11875707 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9833957 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9833957 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 7621844 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2143062 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 2143062 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26447155 — Surrogate Endpoint (SUR): Blood pressure
Study 21812266 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 21812266 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 17976096 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31490251 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 25601535 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18641208 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 10896881 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27230727 — Surrogate Endpoint (SUR): Blood pressure
Study 21373300 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21373300 — Surrogate Endpoint (SUR): Blood pressure
Study 16634993 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16634993 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8877596 — Predictive Biomarker (PRD): BLVRA mRNA
Genes: BLVRA; BLVR; BVR
Study 8877596 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26142227 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 22701683 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8541200 — Surrogate Endpoint (SUR): Serum creatinine
Study 9529260 — Surrogate Endpoint (SUR): Blood pressure
Study 2534464 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11295026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9399608 — Surrogate Endpoint (SUR): Blood pressure
Study 29672567 — Surrogate Endpoint (SUR): Blood pressure
Study 26887645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24749354 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23194103 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 9445494 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7599909 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 31511044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21266669 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 21266669 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 15217941 — Predictive Biomarker (PRD): CDH3 mRNA
Genes: CDH3; CDHP
Study 15217941 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 11263297 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17290150 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 17290150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29618459 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20670842 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study 20670842 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 20670842 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18690760 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18690760 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15621120 — Surrogate Endpoint (SUR): Serum creatinine
Study 15621120 — Surrogate Endpoint (SUR): Blood pressure
Study 11273951 — Surrogate Endpoint (SUR): Serum creatinine
Study 8388583 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8388583 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 26832834 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 10813593 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 1899945 — Surrogate Endpoint (SUR): Blood pressure
Study 24965218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24965218 — Surrogate Endpoint (SUR): Probing pocket depth
Study 2172402 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 26906703 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study 21028969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21028969 — Surrogate Endpoint (SUR): Blood pressure
Study 21028969 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17318893 — Surrogate Endpoint (SUR): Bone mineral density
Study 12008859 — Safety Biomarker (SAF): Interleukin 1
Study 12008859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28536308 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19524839 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8917241 — Surrogate Endpoint (SUR): Blood pressure
Study 1842943 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6626441 — Surrogate Endpoint (SUR): Blood pressure
Study 25581388 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18798083 — Surrogate Endpoint (SUR): Blood pressure
Study 1960234 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 31246713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31246713 — Safety Biomarker (SAF): IL-6 and IL-10
Study 26432913 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15036669 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26914134 — Surrogate Endpoint (SUR): Blood pressure
Study 17981854 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 9752816 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23043965 — Surrogate Endpoint (SUR): Blood pressure
Study 10557001 — Surrogate Endpoint (SUR): Blood pressure
Study 7132728 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 7132728 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27046445 — Surrogate Endpoint (SUR): Blood pressure
Study 23046709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23046709 — Surrogate Endpoint (SUR): Blood pressure
Study 19578221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9706371 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 1396833 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31029863 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study 31029863 — Surrogate Endpoint (SUR): Blood pressure
Study 31029863 — Safety Biomarker (SAF): MTHFR
Study 19777735 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 18082489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18082489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18082489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18082489 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 6993250 — Surrogate Endpoint (SUR): Blood pressure
Study 25381560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28244718 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28244718 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19071184 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15866414 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15866414 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 25751673 — Surrogate Endpoint (SUR): Serum sodium
Study 20347467 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 18554238 — Monitoring Biomarker (MOI): HBV DNA
Study 21794296 — Surrogate Endpoint (SUR): Blood pressure
Study 10971602 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 10971602 — Safety Biomarker (SAF): BDNF
Study 29187046 — Surrogate Endpoint (SUR): Bone mineral density
Study 24786196 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15819670 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 31747948 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29787831 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17557985 — Surrogate Endpoint (SUR): Blood pressure
Study 17557985 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2649822 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18698222 — Surrogate Endpoint (SUR): Blood pressure
Study 14743888 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9711448 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2677374 — Surrogate Endpoint (SUR): Blood pressure
Study 21309005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21309005 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19950087 — Surrogate Endpoint (SUR): Blood pressure
Study 15618271 — Surrogate Endpoint (SUR): Blood pressure
Study 2694923 — Surrogate Endpoint (SUR): Blood pressure
Study 31564841 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31564841 — Surrogate Endpoint (SUR): Blood pressure
Study 27040455 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study 23497636 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 9210530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9210530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9210530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23237107 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17178701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17178701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17178701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7691269 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7691269 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3531038 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3531038 — Surrogate Endpoint (SUR): Blood pressure
Study 26872105 — Surrogate Endpoint (SUR): Blood pressure
Study 24924486 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9430799 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9430799 — Surrogate Endpoint (SUR): Blood pressure
Study 30558006 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25042870 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25042870 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 25042870 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 25042870 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 25042870 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 25042870 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22180560 — Surrogate Endpoint (SUR): Serum creatinine
Study 8927736 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 2055140 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28292320 — Surrogate Endpoint (SUR): Blood pressure
Study 26721135 — Surrogate Endpoint (SUR): Bone mineral density
Study 17923654 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11981075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31487383 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19024003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9324103 — Surrogate Endpoint (SUR): Blood pressure
Study 9324103 — Surrogate Endpoint (SUR): Serum creatinine
Study 31902327 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24096631 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12661776 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12661776 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30929823 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30929823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30929823 — Predictive Biomarker (PRD): VEGFD mRNA
Genes: VEGFD; FIGF
Study 27841945 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study 27841945 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 26002728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26002728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23246855 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 19846544 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16895071 — Surrogate Endpoint (SUR): Bone mineral density
Study 11854119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11854119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11854119 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 3046231 — Surrogate Endpoint (SUR): Serum creatinine
Study 3046231 — Surrogate Endpoint (SUR): Blood pressure
Study 31121022 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31121022 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23704713 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 7507765 — Surrogate Endpoint (SUR): Blood pressure
Study 2906887 — Surrogate Endpoint (SUR): Blood pressure
Study 29632101 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15459598 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 27650174 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 25503550 — Surrogate Endpoint (SUR): Blood pressure
Study 23775875 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 20400651 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 1380588 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 1380588 — Surrogate Endpoint (SUR): Blood pressure
Study 30949987 — Surrogate Endpoint (SUR): Serum creatinine
Study 18070803 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 11920396 — Safety Biomarker (SAF): Interleukin 1
Study 25872641 — Surrogate Endpoint (SUR): Blood pressure
Study 22366046 — Surrogate Endpoint (SUR): Blood pressure
Study 17504357 — Surrogate Endpoint (SUR): Serum creatinine
Study 8275623 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23172934 — Surrogate Endpoint (SUR): Blood pressure
Study 27131611 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 9054757 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 21166851 — Surrogate Endpoint (SUR): Blood pressure
Study 21166851 — Surrogate Endpoint (SUR): Serum creatinine
Study 21166851 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 10766581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1848392 — Surrogate Endpoint (SUR): Blood pressure
Study 12048432 — Surrogate Endpoint (SUR): Blood pressure
Study 2265168 — Surrogate Endpoint (SUR): Blood pressure
Study 29020983 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 22348338 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 22348338 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 22348338 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 2083170 — Surrogate Endpoint (SUR): Blood pressure
Study 31988276 — Monitoring Biomarker (MOI): Cell-free DNA
Study 16713737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23510102 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 26692555 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 23771530 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 17276955 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 3908127 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 26257796 — Surrogate Endpoint (SUR): Blood pressure
Study 21554520 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17542944 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 9516059 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17646493 — Surrogate Endpoint (SUR): Blood pressure
Study 15735200 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 26686567 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20350942 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 16227990 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9456253 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7610506 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 779590 — Surrogate Endpoint (SUR): Blood pressure
Study 19920048 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 19920048 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19920048 — Surrogate Endpoint (SUR): Blood pressure
Study 16954734 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22708640 — Surrogate Endpoint (SUR): Blood pressure
Study 22708640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22708640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22708640 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2261152 — Surrogate Endpoint (SUR): Blood pressure
Study 26921460 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25568553 — Surrogate Endpoint (SUR): Blood pressure
Study 22233204 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22233204 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 22233204 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6