TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1451730 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1451730 — Surrogate Endpoint (SUR): Blood pressure
Study 6331480 — Surrogate Endpoint (SUR): Blood pressure
Study 6331480 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29128648 — Surrogate Endpoint (SUR): Blood pressure
Study 25294380 — Surrogate Endpoint (SUR): Blood pressure
Study 15610070 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12392582 — Surrogate Endpoint (SUR): Blood pressure
Study 7493374 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30844611 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29231294 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21672162 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19106241 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17454224 — Surrogate Endpoint (SUR): Blood pressure
Study 28537325 — Surrogate Endpoint (SUR): Bone mineral density
Study 23692550 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19366271 — Surrogate Endpoint (SUR): Blood pressure
Study 9277655 — Surrogate Endpoint (SUR): Blood pressure
Study 29080906 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 24820639 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 18351428 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28043903 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25887569 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 23213075 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 23213075 — Surrogate Endpoint (SUR): Serum creatinine
Study 19075102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19075102 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17824295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17824295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31707788 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31707788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17224857 — Surrogate Endpoint (SUR): Blood pressure
Study 17224857 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17224857 — Surrogate Endpoint (SUR): Serum potassium
Study 9782691 — Surrogate Endpoint (SUR): Blood pressure
Study 21659972 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 16534012 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16534012 — Surrogate Endpoint (SUR): Blood pressure
Study 12969167 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12969167 — Surrogate Endpoint (SUR): Serum creatinine
Study 8823331 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8823331 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 1333909 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 6385745 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26792372 — Predictive Biomarker (PRD): DUSP3 mRNA
Genes: DUSP3; VHR
Study 12575396 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12575396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2439255 — Surrogate Endpoint (SUR): Serum creatinine
Study 23293335 — Surrogate Endpoint (SUR): Bone mineral density
Study 23293335 — Surrogate Endpoint (SUR): New morphometric vertebral fractures
Study 20825367 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 18288090 — Predictive Biomarker (PRD): KCNAB2 mRNA
Genes: KCNAB2; KCNA2B; KCNK2
Study 18288090 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 18288090 — Predictive Biomarker (PRD): S100A10 mRNA
Genes: S100A10; ANX2LG; CAL1L; CLP11
Study 18288090 — Predictive Biomarker (PRD): HDAC5 mRNA
Genes: HDAC5; KIAA0600
Study 16547529 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9189647 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9189647 — Surrogate Endpoint (SUR): Blood pressure
Study 1439112 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25904773 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25904773 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 25904773 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 25904773 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 25904773 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25904773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17997712 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 10673735 — Surrogate Endpoint (SUR): Blood pressure
Study 30334410 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22574560 — Surrogate Endpoint (SUR): Serum creatinine
Study 22574560 — Surrogate Endpoint (SUR): Serum potassium
Study 6303001 — Surrogate Endpoint (SUR): Blood pressure
Study 28216282 — Surrogate Endpoint (SUR): Blood pressure
Study 19299533 — Surrogate Endpoint (SUR): Blood pressure
Study 7234648 — Surrogate Endpoint (SUR): Blood pressure
Study 31446157 — Surrogate Endpoint (SUR): Blood pressure
Study 25576215 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 24079281 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 24079281 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28492279 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28492279 — Safety Biomarker (SAF): BDNF
Study 25765952 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23268837 — Safety Biomarker (SAF): miR-34c
Genes: MIR34C
Study 23268837 — Safety Biomarker (SAF): miR-375
Genes: MIR375
Study 21115191 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 19900941 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 19900941 — Predictive Biomarker (PRD): GSTA1 mRNA
Genes: GSTA1
Study 12825002 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2279542 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 7002563 — Surrogate Endpoint (SUR): Blood pressure
Study 27182005 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19671802 — Safety Biomarker (SAF): Interleukin 12
Study 27117144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27117144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23965645 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22973094 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 18600390 — Monitoring Biomarker (MOI): HBV DNA
Study 11040232 — Surrogate Endpoint (SUR): Blood pressure
Study 8121965 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3435906 — Surrogate Endpoint (SUR): Blood pressure
Study 30784097 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 30784097 — Surrogate Endpoint (SUR): Platelet count response
Study 23948786 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 20827510 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22374987 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 22374987 — Surrogate Endpoint (SUR): Bone mineral density
Study 12538431 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 31540384 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 31540384 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 31540384 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25510857 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 19006463 — Predictive Biomarker (PRD): CEP70 mRNA
Genes: CEP70; BITE
Study 3056084 — Surrogate Endpoint (SUR): Blood pressure
Study 26468007 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15533865 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 12105160 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 28329121 — Surrogate Endpoint (SUR): Bone mineral density
Study 23704830 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23704830 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23704830 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21422407 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17199134 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 24173029 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22933427 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20530393 — Predictive Biomarker (PRD): NDP mRNA
Genes: NDP; EVR2
Study 1738183 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18572041 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18572041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18572041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18572041 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 16093734 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16093734 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16093734 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10999119 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 10999119 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 12724111 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15302735 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25441408 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 17513190 — Surrogate Endpoint (SUR): Probing pocket depth
Study 9689289 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7863833 — Surrogate Endpoint (SUR): Bone mineral density
Study 21812261 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 16487224 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16627796 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10588226 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27339446 — Surrogate Endpoint (SUR): Total kidney volume
Study 25737517 — Surrogate Endpoint (SUR): Bone mineral density
Study 17124578 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8014493 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 17084803 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 15152826 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 12162755 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9651731 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31277790 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31277790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31277790 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31277790 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31277790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31277790 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30695422 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 21806771 — Surrogate Endpoint (SUR): Blood pressure
Study 7939393 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7939393 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 24670122 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22586319 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 18622420 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 17076227 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27447737 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 27447737 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24796048 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 20543522 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18215613 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18647523 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21114369 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19683591 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15223852 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15223852 — Surrogate Endpoint (SUR): Serum testosterone
Study 9639751 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30033595 — Safety Biomarker (SAF): Interleukin 1
Study 30033595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24598243 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study 18408565 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 18408565 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 9695140 — Surrogate Endpoint (SUR): Blood pressure
Study 29386337 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 12204508 — Surrogate Endpoint (SUR): Blood pressure
Study 8807099 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1581405 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26882041 — Surrogate Endpoint (SUR): Blood pressure
Study 20080850 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 20080850 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 17631211 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17631211 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23122836 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 14715353 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14715353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28520577 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21615671 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19560327 — Surrogate Endpoint (SUR): Blood pressure
Study 16469981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7968373 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21525157 — Surrogate Endpoint (SUR): Bone mineral density
Study 31300595 — Surrogate Endpoint (SUR): Blood pressure
Study 24046070 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 24046070 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 24046070 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 19584895 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19584895 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19584895 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1770553 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29124388 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 27482008 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16077384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11836266 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2901566 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26946985 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23892583 — Surrogate Endpoint (SUR): Bone mineral density
Study 18172627 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15993115 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 24412523 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15644067 — Surrogate Endpoint (SUR): Blood pressure
Study 7762650 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19700798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19700798 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19700798 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19700798 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 9413849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14676071 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26848802 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26848802 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25522396 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11568067 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11568067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11568067 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21799914 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19384914 — Surrogate Endpoint (SUR): Bone mineral density
Study 10207532 — Safety Biomarker (SAF): Interleukin 1
Study 7796342 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 7796342 — Surrogate Endpoint (SUR): Bone mineral density
Study 25475930 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 19047077 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9384477 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 30575682 — Surrogate Endpoint (SUR): Blood pressure
Study 28840638 — Surrogate Endpoint (SUR): Blood pressure
Study 26498451 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22687786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22687786 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9129767 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26850888 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 26850888 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 16492717 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16492717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10840987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10840987 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9412748 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 8466723 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8466723 — Surrogate Endpoint (SUR): Blood pressure
Study 8466723 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28854883 — Monitoring Biomarker (MOI): HBV DNA
Study 18165450 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 18165450 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18165450 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 18165450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17198491 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 25248651 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 8848900 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25582309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31945895 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 8622042 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1777913 — Surrogate Endpoint (SUR): Blood pressure
Study 6811379 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28459717 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 10715622 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9156352 — Surrogate Endpoint (SUR): Blood pressure
Study 16570006 — Surrogate Endpoint (SUR): Serum creatinine
Study 15214181 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30402840 — Predictive Biomarker (PRD): HTATIP2 mRNA
Genes: HTATIP2; CC3; TIP30
Study 26695724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20163197 — Predictive Biomarker (PRD): REEP5 mRNA
Genes: REEP5; C5orf18; DP1; TB2
Study 11848169 — Surrogate Endpoint (SUR): Blood pressure
Study 11848169 — Surrogate Endpoint (SUR): Serum creatinine
Study 21317934 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17048231 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17048231 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31596865 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8638462 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8638462 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31659977 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT