TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22562389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10205747 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10205747 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 31470444 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 30223728 — Surrogate Endpoint (SUR): Blood pressure
Study 28827258 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 25618566 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 14644857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10400415 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26388707 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12435255 — Surrogate Endpoint (SUR): Blood pressure
Study 12435255 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7373255 — Surrogate Endpoint (SUR): Blood pressure
Study 22154243 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 22154243 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 22154243 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 22154243 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28096034 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 23135962 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23135962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23135962 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 23135962 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17316373 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27412317 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22657586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20674983 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 20674983 — Safety Biomarker (SAF): BDNF
Study 29661486 — Surrogate Endpoint (SUR): Blood pressure
Study 25042995 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21136039 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9627377 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2778240 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 2778240 — Predictive Biomarker (PRD): RNASE2 mRNA
Genes: RNASE2; EDN; RNS2
Study 25039412 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25039412 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 25039412 — Surrogate Endpoint (SUR): Blood pressure
Study 21963936 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21963936 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31580506 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28073036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21801246 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 21801246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 21801246 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 21801246 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 21801246 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 10589362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8735175 — Surrogate Endpoint (SUR): Blood pressure
Study 26354331 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26354331 — Predictive Biomarker (PRD): Hormone receptor
Study 23222084 — Surrogate Endpoint (SUR): Bone mineral density
Study 18755361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16839841 — Surrogate Endpoint (SUR): Blood pressure
Study 11208399 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30217672 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25527255 — Surrogate Endpoint (SUR): Blood pressure
Study 22791760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22791760 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22791760 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11952008 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10805055 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31085979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16239366 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7926346 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7926346 — Surrogate Endpoint (SUR): Blood pressure
Study 2668129 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 31325382 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 29954673 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 29954673 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 22682555 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 18822976 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 18822976 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29901652 — Predictive Biomarker (PRD): CPTP mRNA
Genes: CPTP; GLTPD1
Study 17388715 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 14656921 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14656921 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7368100 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24659140 — Surrogate Endpoint (SUR): Blood pressure
Study 12453982 — Surrogate Endpoint (SUR): Blood pressure
Study 10027580 — Surrogate Endpoint (SUR): Blood pressure
Study 10027580 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31734605 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 30770517 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 30770517 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29246960 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19837909 — Surrogate Endpoint (SUR): Serum calcium
Study 19837909 — Surrogate Endpoint (SUR): Bone mineral density
Study 19837909 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 17307412 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11685730 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30905926 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 23512355 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 8321736 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8321736 — Surrogate Endpoint (SUR): Blood pressure
Study 18822473 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 12500983 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17451425 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17451425 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17451425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15070662 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10379634 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10379634 — Surrogate Endpoint (SUR): Blood pressure
Study 8884757 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 8884757 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 8884757 — Predictive Biomarker (PRD): KIAA1217 mRNA
Genes: KIAA1217; SKT
Study 31100620 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 31100620 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23314556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11419712 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7911176 — Surrogate Endpoint (SUR): Blood pressure
Study 31945065 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 30782906 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 28446656 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25831450 — Surrogate Endpoint (SUR): Blood pressure
Study 18223503 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31058892 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 23302735 — Predictive Biomarker (PRD): HCG22 mRNA
Genes: HCG22; G2; PBMUCL2
Study 20079135 — Surrogate Endpoint (SUR): Blood pressure
Study 17904457 — Surrogate Endpoint (SUR): Blood pressure
Study 7784724 — Surrogate Endpoint (SUR): Blood pressure
Study 17511791 — Surrogate Endpoint (SUR): Blood pressure
Study 11352416 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11352416 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31291447 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 21133981 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15217172 — Surrogate Endpoint (SUR): Serum creatinine
Study 11089713 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11089713 — Surrogate Endpoint (SUR): Blood pressure
Study 29708818 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 27043774 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27043774 — Surrogate Endpoint (SUR): Serum creatinine
Study 23252526 — Safety Biomarker (SAF): Interleukin 1
Study 23252526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12464461 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 1981218 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9403278 — Surrogate Endpoint (SUR): Blood pressure
Study 8427864 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8427864 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27347563 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27347563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22978103 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20305128 — Surrogate Endpoint (SUR): Blood pressure
Study 15616068 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 7536681 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7536681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7536681 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17374698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3884410 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 26829494 — Surrogate Endpoint (SUR): Blood pressure
Study 17697902 — Surrogate Endpoint (SUR): Blood pressure
Study 28272011 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22096023 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 17571315 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 18687758 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 18687758 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 2090533 — Surrogate Endpoint (SUR): Blood pressure
Study 30651007 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 30651007 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 29945169 — Safety Biomarker (SAF): Th2 cell
Study 19074930 — Surrogate Endpoint (SUR): Blood pressure
Study 15260961 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 9070554 — Surrogate Endpoint (SUR): Blood pressure
Study 9070554 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8436714 — Surrogate Endpoint (SUR): Blood pressure
Study 26268774 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 23632235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23632235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21590648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21590648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21590648 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21590648 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21590648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9278195 — Surrogate Endpoint (SUR): Serum creatinine
Study 21474675 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 12139546 — Surrogate Endpoint (SUR): Blood pressure
Study 23585346 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23585346 — Surrogate Endpoint (SUR): Bone mineral density
Study 23585346 — Surrogate Endpoint (SUR): Serum calcium
Study 21428726 — Predictive Biomarker (PRD): HMBS mRNA
Genes: HMBS; PBGD; UPS
Study 16929238 — Surrogate Endpoint (SUR): Blood pressure
Study 11255386 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 22031659 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 22031659 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22031659 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22031659 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22031659 — Surrogate Endpoint (SUR): Blood pressure
Study 16410460 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16410460 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16410460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 181193 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 181193 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 19405832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19405832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15291662 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 7180724 — Surrogate Endpoint (SUR): Serum creatinine
Study 21332400 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19541291 — Surrogate Endpoint (SUR): Blood pressure
Study 27541827 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 26437899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9250453 — Surrogate Endpoint (SUR): Blood pressure
Study 27916815 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 9555799 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28096659 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28096659 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 12169328 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 25960826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25960826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25960826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25960826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15454833 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 11406737 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 18253828 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 18253828 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 18253828 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 10569654 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10569654 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29507944 — Surrogate Endpoint (SUR): Blood pressure
Study 10362194 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28131974 — Surrogate Endpoint (SUR): Blood pressure
Study 17159758 — Surrogate Endpoint (SUR): Blood pressure
Study 9833603 — Surrogate Endpoint (SUR): Blood pressure
Study 23800565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23800565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23800565 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23800565 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18769961 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 18769961 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 18769961 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 18769961 — Predictive Biomarker (PRD): TREM2 mRNA
Genes: TREM2
Study 18769961 — Predictive Biomarker (PRD): OSCAR mRNA
Genes: OSCAR
Study 786677 — Surrogate Endpoint (SUR): Blood pressure
Study 26086326 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20357077 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 28131530 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21454393 — Surrogate Endpoint (SUR): Blood pressure
Study 19570573 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19570573 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9767357 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27055417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8808216 — Surrogate Endpoint (SUR): Serum calcium
Study 16997300 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 16997300 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12799786 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11044229 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11044229 — Surrogate Endpoint (SUR): Serum potassium
Study 11044229 — Surrogate Endpoint (SUR): Blood pressure
Study 23919920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22353614 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22353614 — Surrogate Endpoint (SUR): Blood pressure
Study 15930237 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10803042 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10803042 — Surrogate Endpoint (SUR): Blood pressure
Study 1992963 — Surrogate Endpoint (SUR): Blood pressure
Study 1992963 — Surrogate Endpoint (SUR): Serum potassium
Study 26868949 — Surrogate Endpoint (SUR): Blood pressure
Study 21696933 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2143129 — Surrogate Endpoint (SUR): Blood pressure
Study 24994869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24994869 — Safety Biomarker (SAF): MnSOD
Genes: SOD2; GClnc1; IPOB; GC1
Study 11578300 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 17374657 — Surrogate Endpoint (SUR): Blood pressure
Study 15325832 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 8281644 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8281644 — Surrogate Endpoint (SUR): Blood pressure
Study 25873044 — Surrogate Endpoint (SUR): Blood pressure
Study 19803236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 3285836 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 3285836 — Surrogate Endpoint (SUR): Serum calcium
Study 19324346 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30636701 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 24679400 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 21931122 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20032789 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 8610715 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1487306 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29549030 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 24957431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24957431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 22207723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22207723 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1