TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00632775 — Surrogate Endpoint (SUR): Serum sodium
Study NCT02003222 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02003222 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04368013 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02779751 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02779751 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02779751 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02779751 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03647956 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04266392 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01571466 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01780844 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT03866967 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03488394 — Predictive Biomarker (PRD): IDUA mRNA
Genes: IDUA
Study NCT00662519 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT02538341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02369289 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05380336 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT06371755 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00928824 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02795624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00709098 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00145470 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00032435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00684242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00684242 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT00684242 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study NCT00684242 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT00684242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00533494 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00311714 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02481466 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02481466 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02339519 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01411111 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study NCT01411111 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT01411111 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study NCT04310514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00150163 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00150163 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00225407 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03664635 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03182816 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03182816 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00504322 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04588298 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04588298 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02152982 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03767855 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT03841617 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04118192 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03962894 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT02763566 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02763566 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT02763566 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02763566 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02763566 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02763566 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01642901 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03328078 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT02615730 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03739853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04019964 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04019964 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT04589572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04589572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01738815 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02411448 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02411448 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03155997 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03155997 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03155997 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02821065 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00864175 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03184233 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02590276 — Pharmacodynamic Biomarker (PDY): Guanine nucleotide exchange factor C9orf72
Genes: C9orf72; DENND9; DENNL72
Study NCT02590276 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04416984 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04416984 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT00848276 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02220192 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT02855112 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT02827877 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02827877 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00005927 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00005927 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02974621 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03429582 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00001159 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT03496662 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT00001987 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT03427593 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03427593 — Predictive Biomarker (PRD): LRBA mRNA
Genes: LRBA; BGL; CDC4L; LBA
Study NCT03525873 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02782234 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01378650 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study NCT01378650 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study NCT02246621 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02246621 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04689204 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04049604 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00763191 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study NCT03540706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03310879 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03310879 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT03310879 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study NCT03310879 — Predictive Biomarker (PRD): CCND2 mRNA
Genes: CCND2
Study NCT03310879 — Predictive Biomarker (PRD): CCND3 mRNA
Genes: CCND3
Study NCT00976287 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04410796 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03084081 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03613740 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00443001 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02962284 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT01308567 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT00387452 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01814839 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT02097381 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00007163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00007163 — Safety Biomarker (SAF): Interleukin 12
Study NCT00324350 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03554889 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03554889 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00792636 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03240861 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02065193 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study NCT01690572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT02639637 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT02639637 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01236846 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT01233115 — Predictive Biomarker (PRD): HTRA1 mRNA
Genes: HTRA1; HTRA; PRSS11
Study NCT01152398 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02670109 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02670109 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02006758 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00409838 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01433315 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02247375 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study NCT02755259 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02632071 — Predictive Biomarker (PRD): HDAC6 mRNA
Genes: HDAC6; KIAA0901; JM21
Study NCT01231438 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT03257410 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03257410 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT02329639 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00164008 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03532698 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03532698 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02059616 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01428934 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00039234 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study NCT00039234 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00973505 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study NCT00002945 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00274469 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03396302 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04524494 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04524494 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03199404 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study NCT03074656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03403478 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03190603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03829436 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03829436 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study NCT02824458 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02824458 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04337931 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04321603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03102034 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02412189 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04224441 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03022994 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT03022994 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT04663698 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study NCT02378922 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01639131 — Predictive Biomarker (PRD): CHFR mRNA
Genes: CHFR; RNF196
Study NCT01639131 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT00730509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03715140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT03715140 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study NCT03715140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study NCT03715140 — Safety Biomarker (SAF): miR-16
Study NCT02078024 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03004391 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT01310348 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00439413 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT01894074 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01154192 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study NCT01154192 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00277355 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04115423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00086476 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT00086476 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01499316 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02664558 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02664558 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01895582 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04363866 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00470262 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT01866215 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01866215 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05249842 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02035046 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study NCT02620306 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00003222 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00003222 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02990481 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT02392234 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01426412 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01472510 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01340716 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04587648 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT00002748 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04073953 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT02293733 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02293733 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04377308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00645034 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00145236 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02639936 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02190708 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT02190708 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03486600 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00056966 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT02910973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04453332 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00644514 — Predictive Biomarker (PRD): PARP9 mRNA
Genes: PARP9; BAL; BAL1
Study NCT01464710 — Predictive Biomarker (PRD): HTRA1 mRNA
Genes: HTRA1; HTRA; PRSS11
Study NCT01464710 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study NCT00319202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00319202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03856840 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT03856840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00941473 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00582699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03936660 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04138316 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01744067 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00206986 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT02422615 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02422615 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02422615 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00990808 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00580593 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00580593 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04319549 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00557492 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00557492 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02955407 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00931710 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01913691 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT04170114 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03293810 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT02438059 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04403607 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03612375 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03367338 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT03367338 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT02691169 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03978728 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01119755 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02488720 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study NCT00557596 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study NCT01286064 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA