TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04898088 — Predictive Biomarker (PRD): RAD23B mRNA
Genes: RAD23B
Study NCT04898088 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT04898088 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study NCT04898088 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT00524017 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00524017 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00395850 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study NCT00804934 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03538899 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03538899 — Predictive Biomarker (PRD): DCLRE1C mRNA
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study NCT05662488 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02826083 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00151827 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03933293 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03202667 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03202667 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT03202667 — Surrogate Endpoint (SUR): Serum sodium
Study NCT00020072 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT04676269 — Predictive Biomarker (PRD): HOXA10 mRNA
Genes: HOXA10; HOX1H
Study NCT04676269 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study NCT04676269 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04676269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT04676269 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04676269 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03859622 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00514800 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01195636 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study NCT00271336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00274612 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04081987 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03631303 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01130311 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04156399 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03770936 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00242814 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT00003691 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02525835 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01876134 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT01876134 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT00673075 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01628198 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01660529 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03189147 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study NCT03234361 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03253120 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03253120 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01718535 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00296101 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02874547 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00147095 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT01577394 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT04515108 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05172804 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01882660 — Predictive Biomarker (PRD): APCDD1 mRNA
Genes: APCDD1; DRAPC1; FP7019
Study NCT01882660 — Predictive Biomarker (PRD): AXIN2 mRNA
Genes: AXIN2
Study NCT01882660 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study NCT01882660 — Predictive Biomarker (PRD): LGR5 mRNA
Genes: LGR5; GPR49; GPR67
Study NCT01882660 — Predictive Biomarker (PRD): ASCL2 mRNA
Genes: ASCL2; BHLHA45; HASH2
Study NCT01389414 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02923453 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02923453 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT01124071 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01102192 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02336542 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03048877 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT03137329 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00245726 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT05310006 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02662712 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03622255 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT01377870 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02426645 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT02426645 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT04515056 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study NCT01041989 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01861977 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02752178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02752178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00777634 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00898456 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT00898456 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study NCT00898456 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study NCT00898456 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT04746027 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study NCT04409522 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04961632 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02063464 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00745732 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00745732 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02785861 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04442347 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT04368936 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT00667784 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04062825 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01427049 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04088864 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT01513122 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04583956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00503321 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT02422160 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01758367 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT01758367 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00638989 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT01228435 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03615690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01963689 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04632446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04632446 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01764100 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01346891 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study NCT04506450 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03773744 — Predictive Biomarker (PRD): MAGEA3 mRNA
Genes: MAGEA3; MAGE3
Study NCT02305745 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04353609 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02274012 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02274012 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00773825 — Predictive Biomarker (PRD): SNRPN mRNA
Genes: SNRPN; HCERN3; SMN
Study NCT00773825 — Predictive Biomarker (PRD): IGF2R mRNA
Genes: IGF2R; MPRI
Study NCT04365322 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04365322 — Safety Biomarker (SAF): CREM mRNA
Genes: CREM
Study NCT04610554 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02425891 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02909504 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT01542632 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01639001 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04543734 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04299646 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01808144 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT01365975 — Safety Biomarker (SAF): MTHFR
Study NCT01365975 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03715868 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01390142 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT00234169 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00234169 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03144297 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04398550 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05057598 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03038867 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT05071391 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT05071391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05071391 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT05071391 — Safety Biomarker (SAF): Interleukin 1
Study NCT03226301 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01962311 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT01516398 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT00501930 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01214421 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT01889069 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02138097 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01715207 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00445575 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04180826 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT04400552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00581152 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TBX3 mRNA
Genes: TBX3
Study NCT00581152 — Predictive Biomarker (PRD): BMP4 mRNA
Genes: BMP4; BMP2B; DVR4
Study NCT02585739 — Predictive Biomarker (PRD): SPINK1 mRNA
Genes: SPINK1; PSTI
Study NCT00073541 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00073541 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00917345 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00917345 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study NCT01931839 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01717235 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02398032 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01364389 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT01765790 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT01168050 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT02114892 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00952835 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01392352 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04657783 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT00241904 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01337544 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study NCT03576911 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00005521 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01550055 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03479710 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study NCT02377440 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT02377440 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01961063 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02620488 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01605175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02532829 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT00406614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00072098 — Safety Biomarker (SAF): Interleukin 12
Study NCT03652090 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03773029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03773029 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03914053 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT00459680 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01369732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01369732 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT01369732 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03085966 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT02003430 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT03264690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01850160 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01289132 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00820014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03177460 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT01408862 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01408862 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02191813 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT02191813 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT02191813 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study NCT03068767 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05328310 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02724527 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00568841 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00568841 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00568841 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02123368 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00750789 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study NCT00999518 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT01338974 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study NCT02976194 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02976194 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00061607 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT03291860 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00548782 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT00548782 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02755701 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02728388 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01913548 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00118950 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00397423 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02187367 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01868477 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04054271 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT01092052 — Predictive Biomarker (PRD): CDC7 mRNA
Genes: CDC7; CDC7L1
Study NCT04486872 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02801513 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study NCT01092572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00512642 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00459914 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04116268 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02745626 — Surrogate Endpoint (SUR): Bacterial count
Study NCT00001479 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00001479 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01192893 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03310541 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study NCT03310541 — Predictive Biomarker (PRD): AKT2 mRNA
Genes: AKT2
Study NCT03310541 — Predictive Biomarker (PRD): AKT3 mRNA
Genes: AKT3; PKBG
Study NCT01884298 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03875326 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT03845712 — Predictive Biomarker (PRD): TK2 mRNA
Genes: TK2
Study NCT04197999 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05683743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01375751 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04739410 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00899145 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00899145 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT05761262 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT04125277 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT00959010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02476006 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02476006 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02476006 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04072705 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01815866 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT00734162 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00491621 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT00491621 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT00491621 — Predictive Biomarker (PRD): S100A1 mRNA
Genes: S100A1; S100A
Study NCT00678483 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01815099 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00087659 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01445197 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03223389 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT04049344 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study NCT03735186 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03735186 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03735186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01286818 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02147782 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02147782 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02147782 — Surrogate Endpoint (SUR): Serum calcium
Study NCT04189055 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF