TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23447479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1403845 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 3886207 — Surrogate Endpoint (SUR): Blood pressure
Study 18594050 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 18594050 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18594050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16015135 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 10189126 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18331737 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 18331737 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17229242 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 20456355 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 20456355 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 20456355 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 18593524 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 2161578 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31822443 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 31822443 — Predictive Biomarker (PRD): GNLY mRNA
Genes: GNLY; LAG2; NKG5; TLA519
Study 31822443 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 31822443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 31822443 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 28358594 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25271206 — Surrogate Endpoint (SUR): Blood pressure
Study 22131908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19184556 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 15001462 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 20066882 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20066882 — Surrogate Endpoint (SUR): Blood pressure
Study 31446638 — Monitoring Biomarker (MOI): HBV DNA
Study 22078152 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29228247 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 19057612 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 30496407 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 24812896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24812896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18929701 — Surrogate Endpoint (SUR): Serum creatinine
Study 10510993 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10510993 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8748255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8748255 — Safety Biomarker (SAF): Interleukin 1
Study 15925955 — Surrogate Endpoint (SUR): Blood pressure
Study 31291276 — Surrogate Endpoint (SUR): Blood pressure
Study 22348910 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20102847 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20102847 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12598502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12598502 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 12598502 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12598502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12598502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12598502 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12598502 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10100104 — Surrogate Endpoint (SUR): Blood pressure
Study 18381952 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10407522 — Surrogate Endpoint (SUR): Blood pressure
Study 8773212 — Surrogate Endpoint (SUR): Blood pressure
Study 23580597 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17356086 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 1366257 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1366257 — Surrogate Endpoint (SUR): Blood pressure
Study 16188771 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 16188771 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11919120 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 11919120 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 8521296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8521296 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27153360 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 25826143 — Surrogate Endpoint (SUR): Blood pressure
Study 15472179 — Surrogate Endpoint (SUR): Bone mineral density
Study 11558856 — Surrogate Endpoint (SUR): Blood pressure
Study 11558856 — Surrogate Endpoint (SUR): Serum uric acid
Study 31269876 — Surrogate Endpoint (SUR): Bone mineral density
Study 25108027 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23551723 — Surrogate Endpoint (SUR): Blood pressure
Study 11012556 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29699812 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 27003829 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 27003829 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 18555574 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18555574 — Surrogate Endpoint (SUR): Blood pressure
Study 15290734 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 11263764 — Surrogate Endpoint (SUR): Bone mineral density
Study 9146328 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8174879 — Predictive Biomarker (PRD): LGALSL mRNA
Genes: LGALSL; GRP; HSPC159
Study 29494855 — Surrogate Endpoint (SUR): Blood pressure
Study 29494855 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24196521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24196521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21641365 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19365563 — Surrogate Endpoint (SUR): Blood pressure
Study 9210690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3144919 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22949472 — Surrogate Endpoint (SUR): Blood pressure
Study 15499622 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18317253 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17129496 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12840632 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 6541538 — Surrogate Endpoint (SUR): Blood pressure
Study 11689299 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 26889783 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26889783 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26215196 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 19034875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10881066 — Surrogate Endpoint (SUR): Serum sodium
Study 1974506 — Surrogate Endpoint (SUR): Blood pressure
Study 7030149 — Surrogate Endpoint (SUR): Blood pressure
Study 10389774 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10389774 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 10389774 — Surrogate Endpoint (SUR): Blood pressure
Study 20660830 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 18413423 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 12439845 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10529135 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22976566 — Surrogate Endpoint (SUR): Probing pocket depth
Study 9417816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9417816 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9417816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28207505 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22959634 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17028221 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29173604 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29173604 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23169517 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 23169517 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28157380 — Surrogate Endpoint (SUR): Blood pressure
Study 20001460 — Surrogate Endpoint (SUR): Blood pressure
Study 11501230 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11501230 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23885614 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25617577 — Surrogate Endpoint (SUR): Hematologic response
Study 11642001 — Surrogate Endpoint (SUR): Blood pressure
Study 30402489 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21856022 — Surrogate Endpoint (SUR): Blood pressure
Study 10913939 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30867552 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 18823468 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18823468 — Surrogate Endpoint (SUR): Blood pressure
Study 14684754 — Surrogate Endpoint (SUR): Blood pressure
Study 31869338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27010951 — Surrogate Endpoint (SUR): Blood pressure
Study 25193393 — Surrogate Endpoint (SUR): Blood pressure
Study 25193393 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31719084 — Surrogate Endpoint (SUR): Blood pressure
Study 30188495 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26709933 — Surrogate Endpoint (SUR): Blood pressure
Study 17601803 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 15465623 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 7888256 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 28290994 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22434361 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22434361 — Surrogate Endpoint (SUR): Blood pressure
Study 19337745 — Predictive Biomarker (PRD): PCLO mRNA
Genes: PCLO; ACZ; KIAA0559
Study 15623613 — Predictive Biomarker (PRD): FMO3 mRNA
Genes: FMO3
Study 10510926 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31046700 — Monitoring Biomarker (MOI): HBV DNA
Study 28538361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23479383 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18800142 — Surrogate Endpoint (SUR): Blood pressure
Study 9773780 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16331116 — Surrogate Endpoint (SUR): Blood pressure
Study 8833216 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 8833216 — Surrogate Endpoint (SUR): Bone mineral density
Study 3926567 — Surrogate Endpoint (SUR): Blood pressure
Study 12048320 — Surrogate Endpoint (SUR): Blood pressure
Study 31498125 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31498125 — Safety Biomarker (SAF): BDNF
Study 26514213 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22546942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22546942 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 22546942 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22546942 — Safety Biomarker (SAF): Interleukin 1
Study 20721930 — Surrogate Endpoint (SUR): Bone mineral density
Study 15247755 — Surrogate Endpoint (SUR): Serum testosterone
Study 9439492 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9439492 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15892085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10862528 — Surrogate Endpoint (SUR): Bone mineral density
Study 26247960 — Predictive Biomarker (PRD): PLAT mRNA
Genes: PLAT
Study 22658422 — Surrogate Endpoint (SUR): Blood pressure
Study 16249738 — Surrogate Endpoint (SUR): Serum creatinine
Study 12152001 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30562710 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28434467 — Surrogate Endpoint (SUR): Blood pressure
Study 12394804 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12394804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31916229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25200354 — Monitoring Biomarker (MOI): HBV DNA
Study 22733398 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 22733398 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22733398 — Surrogate Endpoint (SUR): Serum testosterone
Study 30466421 — Surrogate Endpoint (SUR): Blood pressure
Study 2638619 — Predictive Biomarker (PRD): DTL mRNA
Genes: DTL; CDT2; CDW1; DCAF2; L2DTL; RAMP
Study 23808439 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23808439 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21653833 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19543851 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19543851 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 16423676 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11737373 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9506654 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9506654 — Surrogate Endpoint (SUR): Blood pressure
Study 28824296 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 6602783 — Surrogate Endpoint (SUR): Blood pressure
Study 20837645 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 20837645 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 16224161 — Surrogate Endpoint (SUR): Serum calcium
Study 16224161 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16224161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22985270 — Surrogate Endpoint (SUR): Bone mineral density
Study 15448036 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 15448036 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 12095057 — Surrogate Endpoint (SUR): Serum creatinine
Study 12095057 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 2339965 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17188121 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 2907408 — Surrogate Endpoint (SUR): Blood pressure
Study 16875041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16875041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10773785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 10773785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8638533 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 8102631 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8102631 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21606869 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19115653 — Surrogate Endpoint (SUR): Blood pressure
Study 10966535 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29322301 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 29322301 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18832434 — Surrogate Endpoint (SUR): Blood pressure
Study 15957829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6233546 — Surrogate Endpoint (SUR): Blood pressure
Study 18696354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18696354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18696354 — Predictive Biomarker (PRD): GSTA1 mRNA
Genes: GSTA1
Study 18696354 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8672931 — Surrogate Endpoint (SUR): Blood pressure
Study 1828309 — Surrogate Endpoint (SUR): Blood pressure
Study 7104157 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7104157 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7104157 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7104157 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7104157 — Surrogate Endpoint (SUR): Blood pressure
Study 27834446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20631056 — Surrogate Endpoint (SUR): Blood pressure
Study 15734599 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12472620 — Surrogate Endpoint (SUR): Serum testosterone
Study 29098381 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20151824 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 18292586 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 18292586 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17196519 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12192663 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 7551660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7551660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7551660 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7551660 — Safety Biomarker (SAF): Interleukin 1
Study 2192197 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 715133 — Surrogate Endpoint (SUR): Blood pressure
Study 7922005 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7922005 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 21531236 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9082588 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9082588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6094194 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9644282 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 3372718 — Surrogate Endpoint (SUR): Blood pressure
Study 8228792 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8228792 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26450639 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26450639 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26450639 — Surrogate Endpoint (SUR): Blood pressure
Study 15983962 — Surrogate Endpoint (SUR): Blood pressure
Study 12853744 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10539816 — Surrogate Endpoint (SUR): Blood pressure
Study 8732962 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 1815967 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19563288 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 11828905 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 31539061 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21455724 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 9050957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25963336 — Predictive Biomarker (PRD): ORMDL3 mRNA
Genes: ORMDL3