TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03194035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03194035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03194035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02633280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00085124 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT00145704 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04447417 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT04293497 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study NCT01101009 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00456963 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00844662 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT00132379 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study NCT00960674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02391441 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01479413 — Predictive Biomarker (PRD): DISC1 mRNA
Genes: DISC1; KIAA0457
Study NCT03397173 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study NCT02990637 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00691223 — Predictive Biomarker (PRD): PORCN mRNA
Genes: PORCN; MG61; PORC; PPN
Study NCT04450888 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04140838 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study NCT04140838 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study NCT04140838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02000986 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02395666 — Predictive Biomarker (PRD): ODC1 mRNA
Genes: ODC1
Study NCT04449601 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03947996 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02330965 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study NCT00552214 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03904810 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03904810 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03904810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03904810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04223583 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT00877110 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03516292 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT03642015 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04516486 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04516486 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study NCT04603612 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04603612 — Predictive Biomarker (PRD): ANXA10 mRNA
Genes: ANXA10; ANX14
Study NCT04603612 — Predictive Biomarker (PRD): UPK1B mRNA
Genes: UPK1B; TSPAN20
Study NCT04603612 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT04603612 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study NCT01925274 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01925274 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT00559754 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00559754 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00559754 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00559754 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01543971 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00145171 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03634644 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT02150369 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01792271 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT03997747 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT03997747 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT05933304 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02219035 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02219035 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT03238144 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study NCT04506749 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00079768 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT03130608 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00547235 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT02127047 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02127047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03801083 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT02700022 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT02787551 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03880279 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00591266 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01135212 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04408131 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02207400 — Surrogate Endpoint (SUR): Bacterial count
Study NCT00512967 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02084095 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT05352373 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02368782 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00761371 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04276337 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04276337 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04276337 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00977769 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02338401 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT03166839 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02497833 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study NCT02280538 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03629210 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02302573 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study NCT03701802 — Predictive Biomarker (PRD): CD101 mRNA
Genes: CD101; EWI101; IGSF2; V7
Study NCT02130024 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02130024 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02130024 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03219268 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03659955 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01982578 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT00810732 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03979131 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT03227328 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03227328 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03951233 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03951233 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00005490 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02636127 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study NCT00195572 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT02423811 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT02423811 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study NCT02423811 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT02423811 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study NCT02423811 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04443387 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT02442206 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01423019 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01891110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04174105 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT01182818 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002637 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00002637 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01874743 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT01874743 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01874743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01874743 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT00595465 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02848599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02848599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02479269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00331864 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00331864 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03772951 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03772951 — Safety Biomarker (SAF): BDNF
Study NCT02849886 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study NCT00119990 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03571308 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03697980 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01062451 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02254083 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00580996 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03098355 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03098355 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03098355 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study NCT03098355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03644680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00887939 — Safety Biomarker (SAF): Interleukin 1
Study NCT02583542 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT06193525 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00175695 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02429427 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04575454 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT03274232 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00807131 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05100758 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT05100758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05100758 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT00528827 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00876876 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01865188 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02777710 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02777710 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02777710 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study NCT04315025 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03872401 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03919253 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03875768 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00315146 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT00176787 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01144208 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00179543 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02768948 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT02147184 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02268617 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03946514 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03946514 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03761693 — Predictive Biomarker (PRD): ACADM mRNA
Genes: ACADM
Study NCT02900612 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02900612 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03709290 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT03709290 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT03984955 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02626767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02626767 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02734082 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01497717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03547258 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00082186 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03442088 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT04027179 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02617888 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT00185835 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00185835 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00757120 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study NCT03064230 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03873610 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT03873610 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT03605212 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT01921270 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study NCT06468761 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00006334 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00616564 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00616564 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01609231 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02366988 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT00493532 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01067066 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study NCT01480531 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04193358 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04151173 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT03090438 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT03983993 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01161303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00586651 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT02401542 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT04306900 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study NCT02108782 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03104322 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01355055 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03814473 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00224848 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00224848 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02004600 — Predictive Biomarker (PRD): COL7A1 mRNA
Genes: COL7A1
Study NCT04822480 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04357782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04357782 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT00005673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01303783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00302263 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01008176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01008176 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01008176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01389271 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02024555 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03653195 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT03866226 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02685046 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02685046 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT03459261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03459261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03459261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03459261 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT03459261 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03207204 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT03207204 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT01540565 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01540565 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03177603 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03177603 — Pharmacodynamic Biomarker (PDY): RAS peptides
Study NCT01424709 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01424709 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study NCT00736814 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT00736814 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study NCT03141099 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02167464 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02167464 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00239304 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03739775 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02837276 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04439149 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT01351142 — Predictive Biomarker (PRD): EIF2AK2 mRNA
Genes: EIF2AK2; PKR; PRKR
Study NCT01351142 — Safety Biomarker (SAF): Interleukin 1
Study NCT00371605 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00371605 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00371605 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03343366 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT01481883 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02848170 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00412932 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03277690 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT01703169 — Surrogate Endpoint (SUR): Platelet count response
Study NCT04161755 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01455714 — Predictive Biomarker (PRD): SDC4 mRNA
Genes: SDC4
Study NCT01455714 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT00315614 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02372383 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT02019277 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05134064 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27