TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9829840 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8273807 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11842294 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11842294 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2757939 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31854193 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 11511297 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 11511297 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 29042415 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29042415 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study 26140473 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8298548 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 20008860 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20008860 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 23195001 — Surrogate Endpoint (SUR): Total kidney volume
Study 20018523 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20018523 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20018523 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20018523 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20018523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12895199 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12895199 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29424155 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23313606 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19463127 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 389037 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 389037 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 22805174 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20864621 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17451575 — Safety Biomarker (SAF): Hyaluronic acid
Study 2567127 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2567127 — Surrogate Endpoint (SUR): Blood pressure
Study 26418868 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 12149103 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12149103 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 12149103 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12149103 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9794859 — Surrogate Endpoint (SUR): Blood pressure
Study 30077564 — Surrogate Endpoint (SUR): Blood pressure
Study 26360148 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15764752 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9918268 — Surrogate Endpoint (SUR): Bone mineral density
Study 7493436 — Surrogate Endpoint (SUR): Blood pressure
Study 31093681 — Surrogate Endpoint (SUR): Blood pressure
Study 15366587 — Surrogate Endpoint (SUR): Bone mineral density
Study 11422018 — Surrogate Endpoint (SUR): Blood pressure
Study 29573863 — Safety Biomarker (SAF): Hyaluronic acid
Study 25416642 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10426831 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15223851 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15223851 — Surrogate Endpoint (SUR): Blood pressure
Study 15223851 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 2957971 — Surrogate Endpoint (SUR): Serum calcium
Study 29391492 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 12475836 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29629665 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 20658369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20658369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10028299 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 1313484 — Surrogate Endpoint (SUR): Blood pressure
Study 31280648 — Surrogate Endpoint (SUR): Blood pressure
Study 23380186 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23380186 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14673517 — Surrogate Endpoint (SUR): Bone mineral density
Study 12361194 — Surrogate Endpoint (SUR): Blood pressure
Study 8109547 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8109547 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17301091 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 14982484 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 28057378 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 15700052 — Surrogate Endpoint (SUR): Bone mineral density
Study 6116608 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 23963633 — Surrogate Endpoint (SUR): Bone mineral density
Study 16008596 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24531662 — Surrogate Endpoint (SUR): Blood pressure
Study 24531662 — Surrogate Endpoint (SUR): Serum calcium
Study 15668873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9828799 — Surrogate Endpoint (SUR): Bone mineral density
Study 26304482 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 8385183 — Surrogate Endpoint (SUR): Blood pressure
Study 8385183 — Surrogate Endpoint (SUR): Serum potassium
Study 24814039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20090540 — Surrogate Endpoint (SUR): Blood pressure
Study 31226920 — Surrogate Endpoint (SUR): Blood pressure
Study 30153581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26597740 — Surrogate Endpoint (SUR): Blood pressure
Study 17341558 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 17341558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23708155 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23708155 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11401931 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20876343 — Surrogate Endpoint (SUR): Blood pressure
Study 12797455 — Safety Biomarker (SAF): MTHFR
Study 25008473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11092773 — Surrogate Endpoint (SUR): Blood pressure
Study 29930161 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26702872 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 17386354 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17386354 — Surrogate Endpoint (SUR): Blood pressure
Study 3079939 — Surrogate Endpoint (SUR): Blood pressure
Study 31714954 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 31714954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31714954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31714954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24890138 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10554416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10554416 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8908527 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8908527 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28052714 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19935591 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 19935591 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 19935591 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3123153 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 7742905 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 2285657 — Surrogate Endpoint (SUR): Blood pressure
Study 8630596 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8630596 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8630596 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 27097165 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 22710579 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 18706417 — Safety Biomarker (SAF): Interleukin 12
Study 12698115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19543081 — Surrogate Endpoint (SUR): Blood pressure
Study 30091545 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21534239 — Surrogate Endpoint (SUR): Blood pressure
Study 15381650 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23110471 — Surrogate Endpoint (SUR): Blood pressure
Study 27093744 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31623042 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 31623042 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 23090718 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21883353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21883353 — Monitoring Biomarker (MOI): Procalcitonin
Study 21883353 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 17309949 — Surrogate Endpoint (SUR): Blood pressure
Study 15152059 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9289367 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3114663 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 16702182 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31752637 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 12707726 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29482649 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23901798 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 22374842 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 28471840 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16924035 — Predictive Biomarker (PRD): PYGM mRNA
Genes: PYGM
Study 9236587 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 31830535 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 27841946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27841946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27841946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12638032 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10576398 — Surrogate Endpoint (SUR): Blood pressure
Study 30641691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9029226 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7953034 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 31645162 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 16828939 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 30442550 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30442550 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26135853 — Surrogate Endpoint (SUR): Blood pressure
Study 11593107 — Surrogate Endpoint (SUR): Serum uric acid
Study 11593107 — Surrogate Endpoint (SUR): Blood pressure
Study 9704709 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 9704709 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9704709 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25657064 — Surrogate Endpoint (SUR): Serum creatinine
Study 25657064 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 12564351 — Surrogate Endpoint (SUR): Blood pressure
Study 10370789 — Pharmacodynamic Biomarker (PDY): DNA topoisomerase I
Genes: TOP1
Study 18948611 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 6437814 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28190578 — Surrogate Endpoint (SUR): Blood pressure
Study 22882288 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 17265483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10220204 — Surrogate Endpoint (SUR): Blood pressure
Study 6426075 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19889829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19889829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19889829 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 2305976 — Surrogate Endpoint (SUR): Blood pressure
Study 30226009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28374969 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 11083748 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27067196 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27067196 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27067196 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27067196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22305890 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 11391543 — Monitoring Biomarker (MOI): HBV DNA
Study 7970428 — Surrogate Endpoint (SUR): Blood pressure
Study 31201949 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 26806502 — Surrogate Endpoint (SUR): Blood pressure
Study 19373213 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 17011500 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 17011500 — Predictive Biomarker (PRD): NPY5R mRNA
Genes: NPY5R; NPYR5
Study 9299885 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 29482983 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29482983 — Predictive Biomarker (PRD): Hormone receptor
Study 22149875 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16055957 — Surrogate Endpoint (SUR): Bone mineral density
Study 550621 — Surrogate Endpoint (SUR): Blood pressure
Study 30144819 — Surrogate Endpoint (SUR): Blood pressure
Study 26897446 — Surrogate Endpoint (SUR): Blood pressure
Study 25048381 — Surrogate Endpoint (SUR): Bone mineral density
Study 20219763 — Surrogate Endpoint (SUR): Blood pressure
Study 17714465 — Predictive Biomarker (PRD): MUC22 mRNA
Genes: MUC22; G4; PBMUCL1
Study 11991216 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8732151 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 8732151 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8732151 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25428337 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22459724 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 17540662 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8071037 — Surrogate Endpoint (SUR): Blood pressure
Study 26044218 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 17187274 — Safety Biomarker (SAF): Hyaluronic acid
Study 31730174 — Safety Biomarker (SAF): miR-652
Genes: MIR652
Study 31730174 — Predictive Biomarker (PRD): miR-106b
Genes: MIR106B
Study 31730174 — Safety Biomarker (SAF): miR-206
Genes: MIR206
Study 26333111 — Surrogate Endpoint (SUR): Blood pressure
Study 24135894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27019339 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 12079562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12079562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12079562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12079562 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7808223 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 2698946 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2698946 — Surrogate Endpoint (SUR): Blood pressure
Study 17275886 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26033153 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16849758 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 10065667 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10065667 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7568639 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7568639 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 31915790 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 28765118 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17028482 — Surrogate Endpoint (SUR): Blood pressure
Study 12230021 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9717985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 2695815 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 6184571 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31711858 — Surrogate Endpoint (SUR): Blood pressure
Study 12074403 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12074403 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10091816 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28337029 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 28337029 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 25196890 — Surrogate Endpoint (SUR): Serum potassium
Study 21261935 — Surrogate Endpoint (SUR): Blood pressure
Study 9159303 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 16439435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1373956 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 1373956 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 28708705 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25465773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19114224 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19114224 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17548953 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15010623 — Surrogate Endpoint (SUR): Serum creatinine
Study 11357169 — Safety Biomarker (SAF): Interleukin 1
Study 23939263 — Surrogate Endpoint (SUR): Blood pressure
Study 23939263 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21706359 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18390643 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 12614286 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27598511 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27598511 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15759817 — Monitoring Biomarker (MOI): HBV DNA
Study 10504127 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 29891331 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29891331 — Safety Biomarker (SAF): BDNF
Study 29891331 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24435414 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17570119 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 17570119 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12401613 — Surrogate Endpoint (SUR): Blood pressure
Study 6991164 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31050709 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31050709 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 31050709 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 23292882 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 23292882 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29677629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29677629 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF