TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23442255 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25535596 — Surrogate Endpoint (SUR): Blood pressure
Study 8950881 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31097515 — Surrogate Endpoint (SUR): Blood pressure
Study 27987395 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25359163 — Surrogate Endpoint (SUR): Blood pressure
Study 26945812 — Surrogate Endpoint (SUR): Blood pressure
Study 26945812 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20923529 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12920059 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8265515 — Surrogate Endpoint (SUR): Blood pressure
Study 2869848 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 2869848 — Surrogate Endpoint (SUR): Blood pressure
Study 19563454 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19563454 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7528299 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7528299 — Surrogate Endpoint (SUR): Blood pressure
Study 9075040 — Surrogate Endpoint (SUR): Blood pressure
Study 31653518 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23571810 — Safety Biomarker (SAF): DRD3
Study 20974485 — Surrogate Endpoint (SUR): Blood pressure
Study 9682673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9682673 — Safety Biomarker (SAF): Interleukin 1
Study 9682673 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18371483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8173689 — Surrogate Endpoint (SUR): Blood pressure
Study 24059690 — Surrogate Endpoint (SUR): Blood pressure
Study 23420326 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 23420326 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 23420326 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23420326 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16324915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8971428 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 1317691 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 1317691 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 6742538 — Surrogate Endpoint (SUR): Blood pressure
Study 22855332 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10030791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10030791 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10030791 — Safety Biomarker (SAF): Interleukin 1
Study 27486204 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 27486204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12751807 — Surrogate Endpoint (SUR): Blood pressure
Study 8462137 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20535924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20535924 — Safety Biomarker (SAF): Interleukin 1
Study 17214996 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 15947771 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 22042783 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8550130 — Surrogate Endpoint (SUR): Blood pressure
Study 19439458 — Surrogate Endpoint (SUR): Blood pressure
Study 19439458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8593994 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 2576667 — Surrogate Endpoint (SUR): Blood pressure
Study 1269217 — Surrogate Endpoint (SUR): Blood pressure
Study 24673076 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 15960405 — Surrogate Endpoint (SUR): Blood pressure
Study 2511023 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 25922190 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16720024 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11444499 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 23252003 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17183628 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14504915 — Surrogate Endpoint (SUR): Bone mineral density
Study 14504915 — Surrogate Endpoint (SUR): Serum calcium
Study 14504915 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20177360 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15601806 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10958599 — Surrogate Endpoint (SUR): Serum creatinine
Study 26446482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26446482 — Surrogate Endpoint (SUR): Blood pressure
Study 24026038 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17098421 — Predictive Biomarker (PRD): ACRC mRNA
Genes: GCNA; ACRC
Study 9447285 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9447285 — Surrogate Endpoint (SUR): Serum testosterone
Study 26759297 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21711204 — Surrogate Endpoint (SUR): Blood pressure
Study 20628153 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 11774104 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11774104 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27919284 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20518617 — Surrogate Endpoint (SUR): Blood pressure
Study 15985013 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15985013 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30535333 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30535333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30535333 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27456494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17331650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 475943 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 475943 — Surrogate Endpoint (SUR): Blood pressure
Study 25955722 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25955722 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 25955722 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25955722 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25955722 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15553661 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15553661 — Surrogate Endpoint (SUR): Blood pressure
Study 27405902 — Surrogate Endpoint (SUR): Serum potassium
Study 27405902 — Surrogate Endpoint (SUR): Serum sodium
Study 19734765 — Predictive Biomarker (PRD): MST1R mRNA
Genes: MST1R; PTK8; RON
Study 15199352 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31820339 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 28668914 — Surrogate Endpoint (SUR): Blood pressure
Study 27684818 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 22498844 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15216550 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 2142081 — Surrogate Endpoint (SUR): Blood pressure
Study 24065421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24065421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24065421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17498850 — Surrogate Endpoint (SUR): Bone mineral density
Study 15017784 — Surrogate Endpoint (SUR): Blood pressure
Study 25030621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16320858 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26935479 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26935479 — Surrogate Endpoint (SUR): Bacterial count
Study 26652009 — Safety Biomarker (SAF): Interleukin 1
Study 26652009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26652009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21559803 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 18718886 — Surrogate Endpoint (SUR): Blood pressure
Study 18718886 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16374471 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 29903761 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 29903761 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 29903761 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 29903761 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 29903761 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 18616866 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 9143171 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 28495809 — Surrogate Endpoint (SUR): Serum potassium
Study 23531329 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 23531329 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 20958277 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25298321 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 20040167 — Surrogate Endpoint (SUR): Blood pressure
Study 18788415 — Surrogate Endpoint (SUR): Serum creatinine
Study 18788415 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18788415 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8914031 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8914031 — Surrogate Endpoint (SUR): Blood pressure
Study 27599328 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11319710 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11319710 — Surrogate Endpoint (SUR): Serum testosterone
Study 23835684 — Surrogate Endpoint (SUR): Blood pressure
Study 23398530 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 12846709 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 11151878 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1732434 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 6326927 — Surrogate Endpoint (SUR): Serum creatinine
Study 15173680 — Surrogate Endpoint (SUR): Blood pressure
Study 15463834 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 2483572 — Surrogate Endpoint (SUR): Blood pressure
Study 17106318 — Surrogate Endpoint (SUR): Blood pressure
Study 10878702 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 10878702 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 8933487 — Surrogate Endpoint (SUR): Plasma ammonia
Study 11464259 — Surrogate Endpoint (SUR): Blood pressure
Study 31583252 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 31583252 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 31583252 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 31583252 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 31583252 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 28353655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28353655 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9435365 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8933789 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10671903 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29352713 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20300014 — Surrogate Endpoint (SUR): Serum testosterone
Study 15972322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25598105 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 18516403 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30194849 — Surrogate Endpoint (SUR): Blood pressure
Study 18648199 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 23886594 — Surrogate Endpoint (SUR): Blood pressure
Study 21975176 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21975176 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 21975176 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 12574098 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12574098 — Surrogate Endpoint (SUR): Blood pressure
Study 9200860 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 3127243 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31664920 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 20956120 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 16846448 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 16846448 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 18942901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10393376 — Surrogate Endpoint (SUR): Serum potassium
Study 10393376 — Surrogate Endpoint (SUR): Serum creatinine
Study 8894571 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8236992 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 25967528 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 26455718 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 2469338 — Surrogate Endpoint (SUR): Blood pressure
Study 28004376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28247686 — Surrogate Endpoint (SUR): Serum testosterone
Study 21299254 — Safety Biomarker (SAF): Reactive oxygen species
Study 21299254 — Surrogate Endpoint (SUR): Serum calcium
Study 21299254 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21299254 — Surrogate Endpoint (SUR): Serum uric acid
Study 11515892 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28193771 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 12660333 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10971305 — Surrogate Endpoint (SUR): Blood pressure
Study 1449107 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19012050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19012050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19012050 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 11505044 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31237134 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31237134 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31237134 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31030590 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28039060 — Surrogate Endpoint (SUR): Serum calcium
Study 23866306 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19125756 — Surrogate Endpoint (SUR): Blood pressure
Study 15673989 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 29742145 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 29742145 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25917574 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25917574 — Surrogate Endpoint (SUR): Bone mineral density
Study 23596051 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8193524 — Surrogate Endpoint (SUR): Blood pressure
Study 29451020 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 19628566 — Predictive Biomarker (PRD): NCOA3 mRNA
Genes: NCOA3; AIB1; BHLHE42; RAC3; TRAM1
Study 19628566 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18469351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18469351 — Predictive Biomarker (PRD): Liver iron
Study 22323351 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 17382108 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10607256 — Monitoring Biomarker (MOI): HBV DNA
Study 27813347 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 27183124 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27183124 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17551297 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9655654 — Surrogate Endpoint (SUR): Blood pressure
Study 27600829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10933407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10933407 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10933407 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 30925267 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30925267 — Safety Biomarker (SAF): BDNF
Study 29122812 — Surrogate Endpoint (SUR): Blood pressure
Study 25300649 — Surrogate Endpoint (SUR): Serum calcium
Study 25300649 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19083482 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30096092 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30096092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29761242 — Surrogate Endpoint (SUR): Serum uric acid
Study 16719601 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8375791 — Surrogate Endpoint (SUR): Blood pressure
Study 31451487 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 28485095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28485095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28485095 — Safety Biomarker (SAF): Interleukin 1
Study 20798662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20798662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23625090 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 23625090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23625090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21543429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21543429 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 15155217 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10764718 — Monitoring Biomarker (MOI): HBV DNA
Study 9077538 — Surrogate Endpoint (SUR): Bone mineral density
Study 16056097 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 7652667 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 23909699 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 18394012 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16842919 — Surrogate Endpoint (SUR): Blood pressure
Study 26947791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19583071 — Surrogate Endpoint (SUR): Blood pressure
Study 3280609 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 31539060 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31539060 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31539060 — Monitoring Biomarker (MOI): Complement C4
Study 19268914 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19268914 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 19268914 — Surrogate Endpoint (SUR): Blood pressure
Study 11385058 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 29603219 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 26182759 — Surrogate Endpoint (SUR): Serum sodium
Study 18335728 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 16572429 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9408513 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1