TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24708667 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24708667 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24709691 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 24710915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24711212 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 24711230 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 24711549 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24711549 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 24711549 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24712435 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24712564 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24714778 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24714778 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 24714806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24714806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24714806 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 24714973 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24715548 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 24715548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24716469 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 24716655 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 24717109 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 24717340 — Surrogate Endpoint (SUR): Blood pressure
Study 24717340 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24717340 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24717420 — Surrogate Endpoint (SUR): Blood pressure
Study 24717623 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 24720900 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24721145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24721422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24721422 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24721691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24721691 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24721691 — Surrogate Endpoint (SUR): Blood pressure
Study 24722393 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 24722393 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 24722393 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24722393 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 24722393 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 24723284 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24723493 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 24723493 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 24725395 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24725395 — Safety Biomarker (SAF): Interleukin 12
Study 24725992 — Predictive Biomarker (PRD): SOX5 mRNA
Genes: SOX5
Study 24725992 — Predictive Biomarker (PRD): NR4A3 mRNA
Genes: NR4A3; CHN; CSMF; MINOR; NOR1; TEC
Study 24725992 — Safety Biomarker (SAF): miR-96
Genes: MIR96
Study 24725992 — Safety Biomarker (SAF): miR-146b
Genes: MIR146B
Study 24725992 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-20a
Genes: MIR20A
Study 24725992 — Predictive Biomarker (PRD): miR-17
Genes: MIR17
Study 24726012 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 24726012 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 24726012 — Predictive Biomarker (PRD): CD160 mRNA
Genes: CD160; BY55
Study 24726012 — Predictive Biomarker (PRD): Hepatitis A virus cellular receptor 2
Genes: HAVCR2; TIM3; TIMD3
Study 24726012 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study 24727704 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24728416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24729079 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24730732 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24733029 — Surrogate Endpoint (SUR): Blood pressure
Study 24733796 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24737128 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 24737778 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24739633 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 24739633 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 24739978 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24740809 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 24740809 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 24740809 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 24741582 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 24742013 — Surrogate Endpoint (SUR): Blood pressure
Study 24743000 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 24743708 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24744276 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 24746173 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 24746569 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24746569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24746841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24747441 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24747441 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24748496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 24750460 — Surrogate Endpoint (SUR): Serum creatinine
Study 24751453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24751453 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24752047 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24752449 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24752945 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 24752945 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 24753538 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 24755610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24756936 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 24756936 — Predictive Biomarker (PRD): IFNGR1 mRNA
Genes: IFNGR1
Study 24757132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24757132 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24758527 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24758527 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 24760136 — Surrogate Endpoint (SUR): Blood pressure
Study 24764221 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24766056 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24766056 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 24766056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24766056 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24766056 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 24766669 — Surrogate Endpoint (SUR): Blood pressure
Study 24766985 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24767767 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24768795 — Surrogate Endpoint (SUR): Blood pressure
Study 24770461 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24770461 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24771350 — Predictive Biomarker (PRD): AKR1C3 mRNA
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 24773774 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24774647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24777247 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 24777716 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24780882 — Predictive Biomarker (PRD): ATXN1 mRNA
Genes: ATXN1; ATX1; SCA1
Study 24780882 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 24780882 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 24782509 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 24782509 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 24782549 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 24786393 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24786929 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 24794806 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24794806 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 24794816 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 24795473 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 24795473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24795473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24795473 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24797180 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 24799481 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 24800949 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24805101 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24805101 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24805101 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 24805101 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 24807459 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24807889 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 24807889 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24807889 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24812403 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24812403 — Predictive Biomarker (PRD): ERBIN mRNA
Genes: ERBIN; ERBB2IP; KIAA1225; LAP2
Study 24816856 — Surrogate Endpoint (SUR): Bone mineral density
Study 24816908 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 24816908 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 24817603 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24817603 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 24817603 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 24817603 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24819256 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 24819685 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 24820045 — Surrogate Endpoint (SUR): Blood pressure
Study 24821881 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24821883 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 24824628 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 24825563 — Predictive Biomarker (PRD): TICRR mRNA
Genes: TICRR; C15orf42
Study 24825563 — Predictive Biomarker (PRD): KIF7 mRNA
Genes: KIF7; UNQ340/PRO539
Study 24825563 — Predictive Biomarker (PRD): RHCG mRNA
Genes: RHCG; C15orf6; CDRC2; PDRC2; RHGK
Study 24826798 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24827131 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24827131 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24827131 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24827131 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24827135 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24829343 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 24829746 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24829746 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24829756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 24829759 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study 24831981 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 24834795 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 24835462 — Surrogate Endpoint (SUR): Bone mineral density
Study 24842896 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 24842896 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 24843649 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24843697 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24843697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24843697 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24843767 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24844673 — Predictive Biomarker (PRD): PDPN mRNA
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 24846037 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24846037 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24846037 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 24846037 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24846037 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 24846037 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24846037 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 24846037 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 24846037 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 24849582 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study 24849582 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 24854384 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24854484 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 24857345 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24857345 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24859363 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study 24859363 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 24859366 — Predictive Biomarker (PRD): IL3RA mRNA
Genes: IL3RA; IL3R
Study 24860718 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24862645 — Surrogate Endpoint (SUR): Blood pressure
Study 24862830 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 24864123 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 24864123 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24864123 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24867540 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24867540 — Predictive Biomarker (PRD): ACKR3 mRNA
Genes: ACKR3; CMKOR1; CXCR7; GPR159; RDC1
Study 24867540 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24867540 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24868099 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24869942 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 24869942 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24870935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24870935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24870935 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24872229 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24872229 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24874071 — Predictive Biomarker (PRD): LTA4H mRNA
Genes: LTA4H; LTA4
Study 24874071 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 24875132 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24875132 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24875132 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 24875672 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 24875672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24875672 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24876081 — Surrogate Endpoint (SUR): Blood pressure
Study 24876244 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 24878054 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 24878825 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 24878825 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 24879333 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 24879788 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 24879813 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24879827 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 24879844 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24881994 — Surrogate Endpoint (SUR): Blood pressure
Study 24882673 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24882673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 24883065 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 24884512 — Predictive Biomarker (PRD): MGLL mRNA
Genes: MGLL
Study 24884512 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24884694 — Surrogate Endpoint (SUR): Blood pressure
Study 24884708 — Surrogate Endpoint (SUR): Serum creatinine
Study 24885112 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 24885137 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24885258 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24885755 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 24886078 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 24886233 — Predictive Biomarker (PRD): MFAP4 mRNA
Genes: MFAP4
Study 24886512 — Predictive Biomarker (PRD): 40S ribosomal protein S6
Genes: RPS6; OK/SW-cl.2
Study 24886572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24886572 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 24888813 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 24888813 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 24889179 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24889179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24889179 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24890385 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24890823 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24890858 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 24890858 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF