TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24549145 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24549145 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16224652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16224652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11953921 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8666002 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 23841960 — Surrogate Endpoint (SUR): Blood pressure
Study 10693157 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 31567764 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19688316 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19688316 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19688316 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18332644 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 11152373 — Surrogate Endpoint (SUR): Blood pressure
Study 11152373 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9593078 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21884146 — Surrogate Endpoint (SUR): Blood pressure
Study 18803554 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 18971535 — Surrogate Endpoint (SUR): Blood pressure
Study 17377092 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 9393379 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26098853 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24871963 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15128052 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 15128052 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor delta
Genes: PPARD
Study 15128052 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 15128052 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 3587722 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3587722 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 22907732 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 22907732 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 11214952 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9200359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24856055 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18175998 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 18175998 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22315331 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 20602109 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2144420 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 788738 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30963410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30963410 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30963410 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30963410 — Safety Biomarker (SAF): Interleukin 1
Study 11258636 — Surrogate Endpoint (SUR): Blood pressure
Study 8357782 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31368861 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31368861 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31368861 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20564923 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20564923 — Surrogate Endpoint (SUR): Blood pressure
Study 30709839 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30709839 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 30709839 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 30709839 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 30709839 — Predictive Biomarker (PRD): ARPC1A mRNA
Genes: ARPC1A; SOP2L
Study 30709839 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30709839 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 30709839 — Predictive Biomarker (PRD): ZKSCAN5 mRNA
Genes: ZKSCAN5; KIAA1015; ZFP95
Study 15012723 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 8970278 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6500760 — Surrogate Endpoint (SUR): Blood pressure
Study 23101545 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23101545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17407214 — Surrogate Endpoint (SUR): Bone mineral density
Study 17407214 — Surrogate Endpoint (SUR): Serum calcium
Study 10449891 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9275755 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9275755 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17852631 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12100779 — Surrogate Endpoint (SUR): Blood pressure
Study 18752466 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 9781630 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7811440 — Surrogate Endpoint (SUR): Blood pressure
Study 9791141 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9791141 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 8162724 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28160873 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 28160873 — Surrogate Endpoint (SUR): New morphometric vertebral fractures
Study 28160873 — Surrogate Endpoint (SUR): Bone mineral density
Study 22111822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18996523 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15576014 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11094787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9125668 — Surrogate Endpoint (SUR): Blood pressure
Study 27510395 — Surrogate Endpoint (SUR): Blood pressure
Study 18525384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31876670 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 25269764 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 9824519 — Surrogate Endpoint (SUR): Blood pressure
Study 18309940 — Surrogate Endpoint (SUR): Bone mineral density
Study 16990386 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 16990386 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8355458 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30071871 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 16644023 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 16644023 — Predictive Biomarker (PRD): CCR1 mRNA
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 16644023 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 16644023 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 16644023 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16644023 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 8973523 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11856089 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 358479 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 19475523 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 19475523 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 11035612 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1353489 — Predictive Biomarker (PRD): Hormone receptor
Study 30215690 — Predictive Biomarker (PRD): TSHR mRNA
Genes: TSHR; LGR3
Study 18842911 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10072012 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7723340 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10355573 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 7732981 — Surrogate Endpoint (SUR): Blood pressure
Study 1975199 — Surrogate Endpoint (SUR): Blood pressure
Study 7298122 — Surrogate Endpoint (SUR): Blood pressure
Study 25709097 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 21406672 — Surrogate Endpoint (SUR): Blood pressure
Study 7988262 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 10205311 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3124680 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17851757 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15226088 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3297679 — Surrogate Endpoint (SUR): Blood pressure
Study 20066735 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20066735 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 19363849 — Surrogate Endpoint (SUR): Blood pressure
Study 19363849 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15811769 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15811769 — Safety Biomarker (SAF): Hyaluronic acid
Study 11566624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11566624 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 29990851 — Surrogate Endpoint (SUR): Blood pressure
Study 7700066 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29865075 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18716414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12455569 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 12455569 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 12455569 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12455569 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7023744 — Surrogate Endpoint (SUR): Blood pressure
Study 23487539 — Predictive Biomarker (PRD): CCL21 mRNA
Genes: CCL21; SCYA21; UNQ784/PRO1600
Study 21652290 — Surrogate Endpoint (SUR): Blood pressure
Study 17785672 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study 10207795 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8998405 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8998405 — Surrogate Endpoint (SUR): Blood pressure
Study 118024 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14634942 — Surrogate Endpoint (SUR): Blood pressure
Study 8877766 — Monitoring Biomarker (MOI): HBV DNA
Study 26859512 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 22482940 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 18929703 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18929703 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16029263 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 10873108 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8641743 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8641743 — Surrogate Endpoint (SUR): Blood pressure
Study 6237916 — Surrogate Endpoint (SUR): Blood pressure
Study 30613065 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 30613065 — Predictive Biomarker (PRD): BANF1 mRNA
Genes: BANF1; BAF; BCRG1
Study 30613065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16398437 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16398437 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10781643 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1492458 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 3927958 — Surrogate Endpoint (SUR): Blood pressure
Study 30293770 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22051059 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 21088400 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19029516 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 14700480 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28339098 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25666325 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 21060206 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 10748791 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27060951 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21594650 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 21594650 — Surrogate Endpoint (SUR): Blood pressure
Study 20638874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10480207 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 7832130 — Surrogate Endpoint (SUR): Blood pressure
Study 22572824 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20500927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12433727 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10527445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10527445 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 10527445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10527445 — Safety Biomarker (SAF): Interleukin 1
Study 7669482 — Surrogate Endpoint (SUR): Blood pressure
Study 26421702 — Surrogate Endpoint (SUR): Blood pressure
Study 24300437 — Surrogate Endpoint (SUR): Blood pressure
Study 28118308 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 1986555 — Surrogate Endpoint (SUR): Serum creatinine
Study 1986555 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1986555 — Surrogate Endpoint (SUR): Serum sodium
Study 1986555 — Surrogate Endpoint (SUR): Serum potassium
Study 20332140 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 12124547 — Safety Biomarker (SAF): Reactive oxygen species
Study 10626341 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7540856 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7540856 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 1952777 — Surrogate Endpoint (SUR): Blood pressure
Study 24403903 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24403903 — Surrogate Endpoint (SUR): Blood pressure
Study 30027283 — Surrogate Endpoint (SUR): Blood pressure
Study 24582914 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24582914 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24582914 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 18834364 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 2532461 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28332851 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 22618304 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 22618304 — Surrogate Endpoint (SUR): Blood pressure
Study 22618304 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9357406 — Surrogate Endpoint (SUR): Blood pressure
Study 30932161 — Surrogate Endpoint (SUR): Bone mineral density
Study 29722482 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29722482 — Predictive Biomarker (PRD): GMDS mRNA
Genes: GMDS
Study 25704621 — Safety Biomarker (SAF): Hyaluronic acid
Study 20948886 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 15558877 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 26613389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26613389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10931125 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 12817100 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 27628221 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24337725 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16227999 — Predictive Biomarker (PRD): SELENOS mRNA
Genes: SELENOS; SELS; VIMP; AD-015; SBBI8
Study 16227999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7869918 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2229837 — Predictive Biomarker (PRD): CEACAM6 mRNA
Genes: CEACAM6; NCA
Study 21909861 — Surrogate Endpoint (SUR): Blood pressure
Study 11083483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11083483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11083483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11083483 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8767378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8767378 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8767378 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 8767378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28722815 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 29228918 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20962162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12734746 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 10374214 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10374214 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6650449 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29072019 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29072019 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 22009807 — Surrogate Endpoint (SUR): Blood pressure
Study 11095453 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 28343596 — Surrogate Endpoint (SUR): Bacterial count
Study 15339439 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 11434828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11434828 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23437789 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23437789 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1524160 — Surrogate Endpoint (SUR): Blood pressure
Study 3511867 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24925372 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 12745724 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1346564 — Surrogate Endpoint (SUR): Blood pressure
Study 19481279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19481279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1503486 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 31176466 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 27640987 — Surrogate Endpoint (SUR): Blood pressure
Study 24272917 — Surrogate Endpoint (SUR): Bone mineral density
Study 12472925 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7778179 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 358755 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 17063108 — Surrogate Endpoint (SUR): Blood pressure
Study 11174337 — Surrogate Endpoint (SUR): Blood pressure
Study 11174337 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8883014 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11753007 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 7654731 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7654731 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2127139 — Surrogate Endpoint (SUR): Blood pressure
Study 27780336 — Surrogate Endpoint (SUR): Blood pressure
Study 23179146 — Surrogate Endpoint (SUR): Bone mineral density
Study 22055098 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH