TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15451058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10770539 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17440998 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 7584882 — Surrogate Endpoint (SUR): Bone mineral density
Study 2318372 — Surrogate Endpoint (SUR): Blood pressure
Study 6965324 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30640655 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28494915 — Surrogate Endpoint (SUR): Blood pressure
Study 8793675 — Surrogate Endpoint (SUR): Serum potassium
Study 30113651 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 30113651 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30113651 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 25332247 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25332247 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25332247 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 25332247 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 25332247 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25332247 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22190020 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12826169 — Surrogate Endpoint (SUR): Bone mineral density
Study 10760045 — Monitoring Biomarker (MOI): HBV DNA
Study 29730798 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10071177 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30723886 — Surrogate Endpoint (SUR): Blood pressure
Study 18413006 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 18413006 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15975964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12874091 — Surrogate Endpoint (SUR): Blood pressure
Study 8026109 — Surrogate Endpoint (SUR): Blood pressure
Study 8026109 — Safety Biomarker (SAF): 51Cr-EDTA
Study 8026109 — Safety Biomarker (SAF): Urinary total protein
Study 790128 — Surrogate Endpoint (SUR): Blood pressure
Study 17726250 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15102080 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 9351881 — Surrogate Endpoint (SUR): Bone mineral density
Study 9817169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9817169 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 17289910 — Predictive Biomarker (PRD): SLC16A4 mRNA
Genes: SLC16A4; MCT4; MCT5
Study 17289910 — Predictive Biomarker (PRD): SLC9A1 mRNA
Genes: SLC9A1; APNH1; NHE1
Study 17289910 — Predictive Biomarker (PRD): MCTS1 mRNA
Genes: MCTS1; MCT1
Study 15326091 — Surrogate Endpoint (SUR): Blood pressure
Study 31098654 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31098654 — Safety Biomarker (SAF): BDNF
Study 22947179 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 22947179 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 22947179 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 22947179 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 16148616 — Surrogate Endpoint (SUR): Blood pressure
Study 8829823 — Surrogate Endpoint (SUR): Blood pressure
Study 8829823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17295293 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8466740 — Surrogate Endpoint (SUR): Blood pressure
Study 29493875 — Predictive Biomarker (PRD): PEF1 mRNA
Genes: PEF1; ABP32; UNQ1845/PRO3573
Study 19788592 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 19788592 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 19788592 — Surrogate Endpoint (SUR): Blood pressure
Study 15671131 — Surrogate Endpoint (SUR): Blood pressure
Study 12730285 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 3993154 — Surrogate Endpoint (SUR): Blood pressure
Study 29995952 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20937127 — Predictive Biomarker (PRD): FMR1
Genes: FMRP; FRAXA; MGC87458
Study 10337860 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7299611 — Surrogate Endpoint (SUR): Blood pressure
Study 31422879 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 30167830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26260705 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26260705 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26019878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26019878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24794447 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 24794447 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24794447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24794447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20921983 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18925530 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 18925530 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15741753 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12393614 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7860762 — Surrogate Endpoint (SUR): Serum sodium
Study 1789379 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30079432 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12269969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12269969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24333089 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 24333089 — Predictive Biomarker (PRD): RHCE mRNA
Genes: RHCE; RHC; RHE
Study 8905024 — Surrogate Endpoint (SUR): Bone mineral density
Study 8905024 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 6124268 — Surrogate Endpoint (SUR): Blood pressure
Study 16950469 — Surrogate Endpoint (SUR): Blood pressure
Study 15052623 — Surrogate Endpoint (SUR): Blood pressure
Study 24360368 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14645968 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 14645968 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24289108 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24289108 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 22781199 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17317135 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17317135 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14748763 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11606503 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 7993155 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7993155 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7993155 — Surrogate Endpoint (SUR): Blood pressure
Study 2191764 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 34186 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30135176 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 10966281 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 6407429 — Surrogate Endpoint (SUR): Blood pressure
Study 24816453 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15699284 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15699284 — Surrogate Endpoint (SUR): Blood pressure
Study 11905407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11905407 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11905407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21377073 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 17414703 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11528581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3371082 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 29661746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26952547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22573363 — Surrogate Endpoint (SUR): Blood pressure
Study 20379853 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18355411 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18355411 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18355411 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 18355411 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 18355411 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26112656 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 22930151 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22930151 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16461190 — Surrogate Endpoint (SUR): Blood pressure
Study 25017001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20018807 — Surrogate Endpoint (SUR): Blood pressure
Study 16556720 — Surrogate Endpoint (SUR): Serum testosterone
Study 12903044 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 26345103 — Predictive Biomarker (PRD): TKT mRNA
Genes: TKT
Study 26345103 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16339664 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1642186 — Surrogate Endpoint (SUR): Serum creatinine
Study 1642186 — Surrogate Endpoint (SUR): Blood pressure
Study 12103382 — Surrogate Endpoint (SUR): Serum creatinine
Study 10408031 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3555578 — Surrogate Endpoint (SUR): Blood pressure
Study 26242380 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 25399229 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25399229 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12593019 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 1744909 — Surrogate Endpoint (SUR): Blood pressure
Study 31703120 — Surrogate Endpoint (SUR): Serum creatinine
Study 31703120 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 9844044 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19491420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2426899 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28939330 — Surrogate Endpoint (SUR): Blood pressure
Study 27225520 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 25074507 — Surrogate Endpoint (SUR): Serum creatinine
Study 25074507 — Surrogate Endpoint (SUR): Blood pressure
Study 12001058 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10469288 — Surrogate Endpoint (SUR): Bone mineral density
Study 2213631 — Surrogate Endpoint (SUR): Blood pressure
Study 23649684 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 11412828 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 11412828 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 11412828 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22905105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22905105 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 29947648 — Surrogate Endpoint (SUR): Blood pressure
Study 8923869 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29590534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27237200 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22382344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17462549 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14718433 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 14718433 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 1433666 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 6376951 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25048075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25048075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22964355 — Surrogate Endpoint (SUR): Blood pressure
Study 12640369 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1501354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30573707 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 29111980 — Surrogate Endpoint (SUR): Serum creatinine
Study 25877422 — Safety Biomarker (SAF): Hyaluronic acid
Study 20635451 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 367865 — Surrogate Endpoint (SUR): Blood pressure
Study 28145158 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28145158 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10952418 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9222947 — Surrogate Endpoint (SUR): Blood pressure
Study 26938953 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26938953 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22278145 — Predictive Biomarker (PRD): GRK4 mRNA
Genes: GRK4; GPRK2L; GPRK4
Study 20578209 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20578209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16208701 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25216508 — Predictive Biomarker (PRD): PDPN mRNA
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 12385861 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12385861 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12385861 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31813423 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29806413 — Surrogate Endpoint (SUR): Bone mineral density
Study 1959859 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27572830 — Predictive Biomarker (PRD): PDE10A mRNA
Genes: PDE10A
Study 19132338 — Surrogate Endpoint (SUR): Serum sodium
Study 19132338 — Surrogate Endpoint (SUR): Blood pressure
Study 17602979 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10678408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10678408 — Surrogate Endpoint (SUR): Bone mineral density
Study 16525751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16525751 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9684746 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26342026 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 26342026 — Predictive Biomarker (PRD): FOXI2 mRNA
Genes: FOXI2
Study 26342026 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PENK mRNA
Genes: PENK
Study 29678360 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 26892135 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26892135 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26892135 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22135493 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9256323 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 3543093 — Surrogate Endpoint (SUR): Blood pressure
Study 3543093 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23479592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14608833 — Surrogate Endpoint (SUR): Blood pressure
Study 12080805 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24296869 — Surrogate Endpoint (SUR): Blood pressure
Study 12948416 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14520725 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 14520725 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1389240 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 17302256 — Monitoring Biomarker (MOI): HBV DNA
Study 3903735 — Surrogate Endpoint (SUR): Blood pressure
Study 12068339 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9247454 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30776777 — Predictive Biomarker (PRD): SIGLEC1 mRNA
Genes: SIGLEC1; SN
Study 30776777 — Predictive Biomarker (PRD): SLC40A1 mRNA
Genes: SLC40A1; FPN; FPN1; IREG1; SLC11A3; MSTP079
Study 29256407 — Predictive Biomarker (PRD): TRPM6 mRNA
Genes: TRPM6; CHAK2
Study 29256407 — Predictive Biomarker (PRD): SLC41A1 mRNA
Genes: SLC41A1
Study 17251278 — Predictive Biomarker (PRD): SLC2A5 mRNA
Genes: SLC2A5; GLUT5
Study 17251278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 17251278 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study 17251278 — Predictive Biomarker (PRD): SLC2A3 mRNA
Genes: SLC2A3; GLUT3
Study 17251278 — Predictive Biomarker (PRD): SLC2A8 mRNA
Genes: SLC2A8; GLUT8; GLUTX1
Study 17251278 — Predictive Biomarker (PRD): SLC2A12 mRNA
Genes: SLC2A12; GLUT12
Study 27562916 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28867538 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 26511807 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15177526 — Surrogate Endpoint (SUR): Blood pressure
Study 8033618 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 31814153 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21173171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17319365 — Surrogate Endpoint (SUR): Blood pressure
Study 9578193 — Safety Biomarker (SAF): DRD2
Study 2651251 — Surrogate Endpoint (SUR): Blood pressure
Study 319871 — Surrogate Endpoint (SUR): Serum potassium
Study 22331686 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22331686 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10937568 — Surrogate Endpoint (SUR): Blood pressure
Study 9295846 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 3470498 — Surrogate Endpoint (SUR): Bacterial count
Study 30518633 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 16088097 — Surrogate Endpoint (SUR): Blood pressure
Study 7869919 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 7869919 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26168857 — Surrogate Endpoint (SUR): Blood pressure
Study 14751370 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9593041 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 3257532 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30320542 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25783161 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16391331 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12673681 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1346807 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 15766294 — Surrogate Endpoint (SUR): Blood pressure
Study 9156785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9156785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9156785 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 9156785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9885797 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 27452327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27452327 — Surrogate Endpoint (SUR): Blood pressure