TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29359480 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29359480 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24846347 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 15969895 — Surrogate Endpoint (SUR): Blood pressure
Study 7955975 — Surrogate Endpoint (SUR): Blood pressure
Study 24059134 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21311355 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 17087620 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14687172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24382338 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24382338 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24382338 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7394133 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23262301 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 22484721 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10472596 — Predictive Biomarker (PRD): A1CF mRNA
Genes: A1CF; ACF; ASP
Study 31912560 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 30667279 — Surrogate Endpoint (SUR): Blood pressure
Study 21725374 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 21725374 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 21725374 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 21725374 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 21725374 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 16785332 — Surrogate Endpoint (SUR): Blood pressure
Study 25873045 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21048039 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22476926 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Growth/differentiation factor 8
Genes: MSTN; GDF8
Study 22476926 — Predictive Biomarker (PRD): FSTL3 mRNA
Genes: FSTL3; FLRG; UNQ674/PRO1308
Study 22476926 — Predictive Biomarker (PRD): SMURF1 mRNA
Genes: SMURF1; KIAA1625
Study 22476926 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FBXO32 mRNA
Genes: FBXO32
Study 21272713 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 9123923 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1536439 — Surrogate Endpoint (SUR): Blood pressure
Study 4038511 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 20099954 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 31836722 — Predictive Biomarker (PRD): DNAH10 mRNA
Genes: DNAH10; KIAA2017
Study 19408036 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 8789903 — Surrogate Endpoint (SUR): Serum sodium
Study 31326975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31326975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31326975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31326975 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25822479 — Predictive Biomarker (PRD): HTR1A mRNA
Genes: HTR1A; ADRB2RL1; ADRBRL1
Study 16479196 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11314565 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 9422294 — Surrogate Endpoint (SUR): Blood pressure
Study 10768275 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11056332 — Predictive Biomarker (PRD): Hormone receptor
Study 26660938 — Surrogate Endpoint (SUR): Blood pressure
Study 23260618 — Surrogate Endpoint (SUR): Blood pressure
Study 18650545 — Surrogate Endpoint (SUR): Blood pressure
Study 17143127 — Surrogate Endpoint (SUR): Blood pressure
Study 17143127 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17143127 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26686313 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26686313 — Predictive Biomarker (PRD): Hormone receptor
Study 24927611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24927611 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 22880214 — Surrogate Endpoint (SUR): Blood pressure
Study 10574478 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8923091 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29552762 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 22543889 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16673835 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12722741 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 8678510 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 31868210 — Surrogate Endpoint (SUR): Blood pressure
Study 16091379 — Surrogate Endpoint (SUR): Blood pressure
Study 16091379 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7637642 — Surrogate Endpoint (SUR): Serum testosterone
Study 2576665 — Surrogate Endpoint (SUR): Blood pressure
Study 28796934 — Surrogate Endpoint (SUR): Blood pressure
Study 22290266 — Safety Biomarker (SAF): DRD2
Study 20642296 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 20642296 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 20642296 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2310656 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 490882 — Surrogate Endpoint (SUR): Blood pressure
Study 25227499 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23326457 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18324419 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16224150 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23180157 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22333107 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22333107 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 30115933 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30115933 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30115933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28655086 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25616438 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 2977393 — Surrogate Endpoint (SUR): Blood pressure
Study 3139337 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 20926529 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19365011 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11264907 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9146855 — Surrogate Endpoint (SUR): Blood pressure
Study 7711007 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30538005 — Predictive Biomarker (PRD): DDAH2 mRNA
Genes: DDAH2; DDAH; G6A; NG30
Study 25439692 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25439692 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23044290 — Surrogate Endpoint (SUR): Serum creatinine
Study 1310103 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 31479804 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 29266675 — Surrogate Endpoint (SUR): Blood pressure
Study 12474066 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 22433304 — Monitoring Biomarker (MOI): HBV DNA
Study 17014428 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 17014428 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 17014428 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 17014428 — Safety Biomarker (SAF): Human leucocyte antigen
Study 8724378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8724378 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 8724378 — Safety Biomarker (SAF): Interleukin 1
Study 8724378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3927062 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29317275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28137501 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25511449 — Predictive Biomarker (PRD): POLD1 mRNA
Genes: POLD1; POLD
Study 21627406 — Surrogate Endpoint (SUR): Blood pressure
Study 19141980 — Predictive Biomarker (PRD): BANF1 mRNA
Genes: BANF1; BAF; BCRG1
Study 12943180 — Surrogate Endpoint (SUR): Blood pressure
Study 12943180 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25362247 — Safety Biomarker (SAF): Hyaluronic acid
Study 12482554 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10839588 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9316528 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2883060 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30384149 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 27287207 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 23323329 — Predictive Biomarker (PRD): IDUA mRNA
Genes: IDUA
Study 16324360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16324360 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16324360 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 16324360 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16324360 — Surrogate Endpoint (SUR): Blood pressure
Study 9502350 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8018759 — Predictive Biomarker (PRD): PNN mRNA
Genes: PNN; DRS; MEMA
Study 11739866 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22364141 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 22364141 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22364141 — Surrogate Endpoint (SUR): Bone mineral density
Study 28711708 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 28711708 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 28711708 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26239086 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22447014 — Surrogate Endpoint (SUR): Blood pressure
Study 19687338 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9772139 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 603844 — Surrogate Endpoint (SUR): Blood pressure
Study 30990549 — Surrogate Endpoint (SUR): Blood pressure
Study 19649649 — Safety Biomarker (SAF): Interleukin 1
Study 19649649 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17623719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25546032 — Surrogate Endpoint (SUR): Blood pressure
Study 21435203 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17276712 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 17276712 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10954759 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10954759 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25262788 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25262788 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 21190450 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23982674 — Predictive Biomarker (PRD): HLF mRNA
Genes: HLF
Study 3134468 — Safety Biomarker (SAF): 51Cr-EDTA
Study 3134468 — Surrogate Endpoint (SUR): Blood pressure
Study 3288695 — Surrogate Endpoint (SUR): Blood pressure
Study 25244801 — Surrogate Endpoint (SUR): Blood pressure
Study 23730989 — Surrogate Endpoint (SUR): Blood pressure
Study 16309554 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11093285 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 29732549 — Surrogate Endpoint (SUR): Serum sodium
Study 24297950 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22459771 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20201749 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20201749 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20201749 — Surrogate Endpoint (SUR): Blood pressure
Study 10334442 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25968966 — Surrogate Endpoint (SUR): Serum sodium
Study 23292288 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 20192950 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 10580184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8334889 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8334889 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18562131 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 18562131 — Predictive Biomarker (PRD): HTR1A mRNA
Genes: HTR1A; ADRB2RL1; ADRBRL1
Study 16202353 — Surrogate Endpoint (SUR): Blood pressure
Study 29691526 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 11848259 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11848259 — Surrogate Endpoint (SUR): Blood pressure
Study 3122349 — Surrogate Endpoint (SUR): Serum sodium
Study 22623266 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 22623266 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 16631000 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11304054 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21861845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12073199 — Surrogate Endpoint (SUR): Serum creatinine
Study 9799972 — Surrogate Endpoint (SUR): Blood pressure
Study 29172739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29172739 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31405706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31405706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27721537 — Surrogate Endpoint (SUR): Serum uric acid
Study 23024023 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20304584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20304584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20304584 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20304584 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17627681 — Surrogate Endpoint (SUR): Blood pressure
Study 15954919 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 15954919 — Surrogate Endpoint (SUR): Blood pressure
Study 15954919 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15649112 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31898090 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 29893222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18804362 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18989245 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18989245 — Surrogate Endpoint (SUR): Serum creatinine
Study 31172717 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31172717 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 8167489 — Surrogate Endpoint (SUR): Blood pressure
Study 10827212 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 19372331 — Surrogate Endpoint (SUR): Blood pressure
Study 16894336 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 6112039 — Surrogate Endpoint (SUR): Blood pressure
Study 27842315 — Surrogate Endpoint (SUR): Serum creatinine
Study 21286719 — Predictive Biomarker (PRD): XRCC2 mRNA
Genes: XRCC2
Study 10521100 — Predictive Biomarker (PRD): CYP21A2 mRNA
Genes: CYP21A2; CYP21; CYP21B
Study 10521100 — Surrogate Endpoint (SUR): Serum testosterone
Study 7595707 — Predictive Biomarker (PRD): Hormone receptor
Study 10971314 — Surrogate Endpoint (SUR): Blood pressure
Study 3241272 — Surrogate Endpoint (SUR): Blood pressure
Study 29189426 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26331290 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20941948 — Surrogate Endpoint (SUR): Bacterial count
Study 16298234 — Predictive Biomarker (PRD): NCAM1 mRNA
Genes: NCAM1; NCAM
Study 14750576 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 14750576 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 6802095 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 18779280 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 18779280 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10075143 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6341684 — Surrogate Endpoint (SUR): Blood pressure
Study 30357394 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21041921 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15858063 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 7697926 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29653645 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 26609282 — Surrogate Endpoint (SUR): Serum testosterone
Study 24023317 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12741348 — Surrogate Endpoint (SUR): Sperm parameters
Study 8835649 — Surrogate Endpoint (SUR): Blood pressure
Study 3907725 — Surrogate Endpoint (SUR): Blood pressure
Study 29106665 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 20508469 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8291920 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 29467598 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29467598 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 23307840 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23307840 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23307840 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17070147 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17070147 — Surrogate Endpoint (SUR): Blood pressure
Study 17070147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 13677262 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 13677262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27468128 — Predictive Biomarker (PRD): NR4A2 mRNA
Genes: NR4A2; NOT; NURR1; TINUR
Study 19004053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19004053 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19004053 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6754331 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30217378 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26890031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19063686 — Surrogate Endpoint (SUR): Serum calcium
Study 19459233 — Surrogate Endpoint (SUR): Blood pressure
Study 16758422 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3093918 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30400122 — Safety Biomarker (SAF): BDNF
Study 30400122 — Safety Biomarker (SAF): Reactive oxygen species
Study 31388683 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31388683 — Surrogate Endpoint (SUR): Blood pressure
Study 9842841 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9842841 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 9842841 — Safety Biomarker (SAF): Th2 cell
Study 25646328 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 14660479 — Surrogate Endpoint (SUR): Blood pressure
Study 30412630 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 30412630 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 30412630 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24895813 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18414370 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15536472 — Surrogate Endpoint (SUR): Blood pressure
Study 8501148 — Surrogate Endpoint (SUR): Bone mineral density
Study 8501148 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31994022 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18592146 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 18592146 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1