TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01084369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01084369 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00129350 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02276235 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02276235 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01016990 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02337309 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study NCT04346927 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00020397 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00825110 — Predictive Biomarker (PRD): GCC1 mRNA
Genes: GCC1
Study NCT04286802 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00185783 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01853527 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study NCT03933163 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT06238427 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT02042495 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT02042495 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study NCT03384602 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02310074 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study NCT00598351 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT03163641 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04067869 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02706691 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT02706691 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT05209087 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01233635 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01233635 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00750113 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01020565 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01111591 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study NCT01386515 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04195555 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT01290094 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04564001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04564001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04487080 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04487080 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04097756 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04166604 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04331691 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01441141 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00370500 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT00370500 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT01885013 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04626856 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03981341 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02965326 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03456947 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02150928 — Surrogate Endpoint (SUR): Serum asparaginase
Study NCT04462926 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04930926 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study NCT04930926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02335840 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03347032 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03649971 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05296707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04099290 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01703442 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00050414 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT00047710 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00674258 — Predictive Biomarker (PRD): TTK mRNA
Genes: TTK; MPS1; MPS1L1
Study NCT00674258 — Predictive Biomarker (PRD): IGF2BP3 mRNA
Genes: IGF2BP3; IMP3; KOC1; VICKZ3
Study NCT00674258 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT01368263 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01368263 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01368263 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01368263 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01982695 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01982695 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04343963 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02772965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03735823 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03735823 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02983045 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT02324842 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06531902 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study NCT03117634 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02709993 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02709993 — Predictive Biomarker (PRD): TAPBP mRNA
Genes: TAPBP; NGS17; TAPA
Study NCT00315224 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03551847 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02102893 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study NCT02102893 — Predictive Biomarker (PRD): SSTR5 mRNA
Genes: SSTR5
Study NCT02615847 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02472366 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03898622 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT01171872 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study NCT03522246 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01838174 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00827996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00128661 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00404027 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04202497 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT01518569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01518569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02979327 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00582465 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03338374 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03925974 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04010344 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02419937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02419937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04444557 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01813006 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT04879888 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03379103 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03011294 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02453282 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02453282 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02453282 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00923013 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03524274 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT04253340 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04019561 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study NCT03275818 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study NCT01998672 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT00721747 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02722980 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03000296 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04426669 — Predictive Biomarker (PRD): CISH mRNA
Genes: CISH; G18
Study NCT02660333 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04355104 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT00546897 — Predictive Biomarker (PRD): Chromosome 5q
Study NCT00380445 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01275586 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT02924883 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00445003 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00445003 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01987011 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03367754 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03455348 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04636697 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01270763 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01985893 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04681703 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02713022 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02109354 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03564561 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT04758260 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT00406068 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT03084822 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04300673 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04135027 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study NCT01198743 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01198743 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT01198743 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT01198743 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01198743 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01094067 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04165239 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04165239 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02945826 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study NCT02276963 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT03827044 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study NCT03214991 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03717350 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03717350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03482427 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00924326 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04459273 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT05939518 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02698982 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03049826 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT03923465 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT04334174 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT02023853 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00535951 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01646788 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT01381705 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study NCT01237522 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study NCT02566330 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00885456 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04385771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00496548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03408119 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03064113 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05733884 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT02107092 — Surrogate Endpoint (SUR): Serum potassium
Study NCT01414972 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04132908 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03099174 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03099174 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04068441 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04086888 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04258150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02414152 — Safety Biomarker (SAF): Interleukin 1
Study NCT03983486 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT03983486 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT03983486 — Predictive Biomarker (PRD): CDKN2C mRNA
Genes: CDKN2C; CDKN6
Study NCT03983486 — Predictive Biomarker (PRD): CKS1B mRNA
Genes: CKS1B; CKS1; PNAS-143; PNAS-16
Study NCT02247752 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00301366 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT02424266 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT02126137 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study NCT02647164 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03089476 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT00095212 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02609295 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT01886326 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04795154 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02616809 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02047071 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03929900 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00297648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01008878 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02683083 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00517530 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03124303 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT04353557 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01606540 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02479893 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT04517162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00624065 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03185039 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study NCT03185039 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT01804777 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01460147 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00195260 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study NCT04109417 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01753895 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03991260 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00972959 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00736970 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05088005 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study NCT05088005 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT03918486 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02242123 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study NCT04527575 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04544787 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00344110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02259270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01590108 — Predictive Biomarker (PRD): APLNR mRNA
Genes: APLNR; AGTRL1; APJ
Study NCT01537861 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04299594 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00890981 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03211403 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT01555411 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03018834 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00076037 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04154579 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00333489 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00547781 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT03636763 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05908864 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03204539 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03026348 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00978822 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02791880 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT00339547 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04192006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04192006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04192006 — Safety Biomarker (SAF): Interleukin 1
Study NCT04192006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04192006 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT04192006 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT04192006 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01482377 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT01900080 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04549077 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04549077 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT02647580 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT00617305 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT00617305 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00868374 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01971619 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04328337 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study NCT02007031 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03182114 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03149653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03648658 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT03659006 — Safety Biomarker (SAF): Interleukin 1