TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8390278 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8390278 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 26079438 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 24787916 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 9639501 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7978186 — Surrogate Endpoint (SUR): Blood pressure
Study 21547610 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17319473 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17319473 — Surrogate Endpoint (SUR): Blood pressure
Study 10599912 — Surrogate Endpoint (SUR): Probing pocket depth
Study 1911016 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6211999 — Surrogate Endpoint (SUR): Serum potassium
Study 30793259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30793259 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15071716 — Surrogate Endpoint (SUR): Blood pressure
Study 9279247 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7525901 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 19119088 — Surrogate Endpoint (SUR): Serum calcium
Study 15587331 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15587331 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21813109 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21813109 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9428831 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8296490 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30150504 — Predictive Biomarker (PRD): IL27
Genes: IL-27; p28; IL27p28; IL-27A; IL27A; MGC71873
Study 15924807 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15924807 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7572772 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 7572772 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 7572772 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 7572772 — Predictive Biomarker (PRD): C9 mRNA
Genes: C9
Study 22247115 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22247115 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17258092 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study 23719683 — Surrogate Endpoint (SUR): Bone mineral density
Study 16679090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15596193 — Surrogate Endpoint (SUR): Serum testosterone
Study 27649551 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27649551 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 27649551 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 27649551 — Predictive Biomarker (PRD): TNFRSF18 mRNA
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study 9679620 — Surrogate Endpoint (SUR): Blood pressure
Study 26782276 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18823912 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 17147514 — Surrogate Endpoint (SUR): Blood pressure
Study 2258895 — Surrogate Endpoint (SUR): Blood pressure
Study 28756278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24494286 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 21482928 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study 17531920 — Surrogate Endpoint (SUR): Blood pressure
Study 11550111 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11550111 — Surrogate Endpoint (SUR): Blood pressure
Study 30334920 — Predictive Biomarker (PRD): CNDP2 mRNA
Genes: CNDP2; CN2; CPGL; HEL-S-13; PEPA
Study 30334920 — Predictive Biomarker (PRD): ABAT mRNA
Genes: ABAT; GABAT
Study 30334920 — Predictive Biomarker (PRD): SLC36A1 mRNA
Genes: SLC36A1; PAT1
Study 28052885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25439429 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 25439429 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17106277 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17106277 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15501926 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2501598 — Surrogate Endpoint (SUR): Blood pressure
Study 25003274 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20580870 — Surrogate Endpoint (SUR): Bone mineral density
Study 2259918 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25815738 — Surrogate Endpoint (SUR): Blood pressure
Study 15829494 — Predictive Biomarker (PRD): GATM mRNA
Genes: GATM; AGAT
Study 31314107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31314107 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 31314107 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31314107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31314107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31314107 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 31314107 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31314107 — Safety Biomarker (SAF): BDNF
Study 23211762 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11231429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11231429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12801957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23451445 — Safety Biomarker (SAF): Hyaluronic acid
Study 27827824 — Predictive Biomarker (PRD): Hepatitis A virus cellular receptor 2
Genes: HAVCR2; TIM3; TIMD3
Study 27827824 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 25808099 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 25808099 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 21834707 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16305056 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7479391 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28265678 — Safety Biomarker (SAF): Interleukin 1
Study 25948780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25022156 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 25022156 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25022156 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11852293 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 23680679 — Surrogate Endpoint (SUR): Blood pressure
Study 15854942 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19444560 — Surrogate Endpoint (SUR): Blood pressure
Study 15020290 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study 8126497 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31895945 — Surrogate Endpoint (SUR): Blood pressure
Study 23102619 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 23102619 — Safety Biomarker (SAF): Nicotinamide phosphoribosyltransferase
Genes: NAMPT; PBEF; PBEF1
Study 23102619 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 10215959 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10215959 — Safety Biomarker (SAF): Hyaluronic acid
Study 8583662 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8583662 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8583662 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8583662 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27258938 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27704317 — Surrogate Endpoint (SUR): Blood pressure
Study 25786369 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 7815242 — Surrogate Endpoint (SUR): Serum uric acid
Study 9895016 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9895016 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 9895016 — Surrogate Endpoint (SUR): Blood pressure
Study 8724889 — Surrogate Endpoint (SUR): Serum creatinine
Study 8724889 — Surrogate Endpoint (SUR): Blood pressure
Study 3295180 — Surrogate Endpoint (SUR): Blood pressure
Study 16563590 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9382121 — Surrogate Endpoint (SUR): Bone mineral density
Study 1313762 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1313762 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31348430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12162817 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 11965231 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 11965231 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 7926293 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 25726209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22825573 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study 17896170 — Surrogate Endpoint (SUR): Blood pressure
Study 26253566 — Surrogate Endpoint (SUR): Blood pressure
Study 21857356 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16879829 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30045107 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 22757691 — Safety Biomarker (SAF): Reactive oxygen species
Study 22757691 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18477409 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18477409 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 18477409 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29726951 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 23582949 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 23582949 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18698881 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 18698881 — Surrogate Endpoint (SUR): Blood pressure
Study 12824786 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12824786 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3555033 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26754643 — Surrogate Endpoint (SUR): Serum uric acid
Study 26754643 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26754643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25048382 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 25048382 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 25048382 — Surrogate Endpoint (SUR): Blood pressure
Study 22172244 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 22169620 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 12572648 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 9448204 — Safety Biomarker (SAF): Reactive oxygen species
Study 782685 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 18671796 — Surrogate Endpoint (SUR): Blood pressure
Study 15342288 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15342288 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2868659 — Surrogate Endpoint (SUR): Blood pressure
Study 29363103 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 16521637 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30095158 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12076342 — Surrogate Endpoint (SUR): Blood pressure
Study 10208495 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10208495 — Surrogate Endpoint (SUR): Blood pressure
Study 7797807 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 2128094 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 368087 — Surrogate Endpoint (SUR): Blood pressure
Study 30808625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23587190 — Surrogate Endpoint (SUR): Serum calcium
Study 14715352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8173851 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 29685343 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11027451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11027451 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11027451 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 8354977 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8354977 — Surrogate Endpoint (SUR): Blood pressure
Study 25172798 — Surrogate Endpoint (SUR): Blood pressure
Study 22415678 — Surrogate Endpoint (SUR): Blood pressure
Study 19944431 — Surrogate Endpoint (SUR): Serum creatinine
Study 19923803 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30957833 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30957833 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23876588 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 18533158 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12204014 — Surrogate Endpoint (SUR): Blood pressure
Study 25575802 — Surrogate Endpoint (SUR): Blood pressure
Study 20524710 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 12792162 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15865094 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15865094 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 1378114 — Surrogate Endpoint (SUR): Blood pressure
Study 30309256 — Surrogate Endpoint (SUR): Blood pressure
Study 26271367 — Surrogate Endpoint (SUR): Blood pressure
Study 19895595 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12066728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22734802 — Surrogate Endpoint (SUR): Blood pressure
Study 18772643 — Surrogate Endpoint (SUR): Blood pressure
Study 16033295 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30150326 — Surrogate Endpoint (SUR): Blood pressure
Study 28916975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28916975 — Safety Biomarker (SAF): Interleukin 1
Study 21174486 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 21174486 — Surrogate Endpoint (SUR): Serum creatinine
Study 17894535 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 7950208 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 7950208 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 15313950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15313950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15313950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15313950 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15313950 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 11557642 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28554988 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study 28554988 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 28554988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25453396 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12913036 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12913036 — Surrogate Endpoint (SUR): Blood pressure
Study 26518044 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23632035 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23632035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17309139 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 9087473 — Surrogate Endpoint (SUR): Bone mineral density
Study 21062180 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 19025625 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 12651645 — Surrogate Endpoint (SUR): Blood pressure
Study 6104554 — Surrogate Endpoint (SUR): Blood pressure
Study 19218044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17374171 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17374171 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15310997 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 31481243 — Surrogate Endpoint (SUR): Blood pressure
Study 17020559 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12837190 — Surrogate Endpoint (SUR): Blood pressure
Study 31310160 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 19330342 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9689432 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 28814835 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28814835 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28814835 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28814835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23155122 — Surrogate Endpoint (SUR): Blood pressure
Study 18823024 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 6421010 — Surrogate Endpoint (SUR): Blood pressure
Study 22822451 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 22822451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22822451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11196553 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study 8818438 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 1610576 — Surrogate Endpoint (SUR): Blood pressure
Study 29524194 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 29524194 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29524194 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 17159195 — Surrogate Endpoint (SUR): Bone mineral density
Study 9239866 — Surrogate Endpoint (SUR): Blood pressure
Study 1295122 — Surrogate Endpoint (SUR): Blood pressure
Study 31790484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31790484 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29458218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26654200 — Surrogate Endpoint (SUR): Blood pressure
Study 18572751 — Monitoring Biomarker (MOI): HBV DNA
Study 29129737 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 20933512 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 12965108 — Surrogate Endpoint (SUR): Blood pressure
Study 1317939 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 1317939 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20435234 — Monitoring Biomarker (MOI): HBV DNA
Study 3283229 — Surrogate Endpoint (SUR): Blood pressure
Study 26351344 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 26351344 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 26351344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23369075 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19168349 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 19168349 — Predictive Biomarker (PRD): RFC1 mRNA
Genes: RFC1; RFC140
Study 16461201 — Surrogate Endpoint (SUR): Blood pressure
Study 9415855 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9415855 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 9415855 — Surrogate Endpoint (SUR): Blood pressure
Study 15837835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1