TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17910637 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 17910637 — Safety Biomarker (SAF): Human leucocyte antigen
Study 17912368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17916243 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 17920064 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17923600 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17923600 — Surrogate Endpoint (SUR): Serum sodium
Study 17923600 — Surrogate Endpoint (SUR): Blood pressure
Study 17925413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17925413 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17938165 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17940483 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17942751 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 17943084 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17951527 — Predictive Biomarker (PRD): Liver iron
Study 17959415 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17959863 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 17959863 — Predictive Biomarker (PRD): Liver iron
Study 17975162 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 17975162 — Safety Biomarker (SAF): Interleukin 12
Study 17981652 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 17996820 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18000186 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18003886 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 18005455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18008060 — Predictive Biomarker (PRD): GCKR mRNA
Genes: GCKR
Study 18021418 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 18025537 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18025537 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 18026714 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18031749 — Surrogate Endpoint (SUR): Blood pressure
Study 18039368 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18039368 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18039992 — Surrogate Endpoint (SUR): Bone mineral density
Study 18042798 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 18042798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18043905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18048643 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 18048643 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 18048643 — Surrogate Endpoint (SUR): Hematologic response
Study 18050221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18055865 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18056840 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 18071030 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 18077791 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18078870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18079362 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 18083847 — Safety Biomarker (SAF): Cytochrome c
Study 18090358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18090358 — Safety Biomarker (SAF): Interleukin 1
Study 18096059 — Pharmacodynamic Biomarker (PDY): DNA topoisomerase I
Genes: TOP1
Study 18163417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18163417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18174826 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 18178411 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18178412 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18182574 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18184959 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18190252 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18201682 — Predictive Biomarker (PRD): SLK mRNA
Genes: SLK; KIAA0204; STK2
Study 18206507 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 18215105 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 18215105 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18218852 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 18218852 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18218852 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 18221542 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18221542 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 18221542 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 18221542 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 18221542 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 18221542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 18222352 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 18231580 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 18253503 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18256394 — Predictive Biomarker (PRD): LMNA mRNA
Genes: LMNA; LMN1
Study 18256394 — Surrogate Endpoint (SUR): Blood pressure
Study 18256395 — Predictive Biomarker (PRD): ATP7A mRNA
Genes: ATP7A; MC1; MNK
Study 18284320 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18289410 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 18298130 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 18298856 — Predictive Biomarker (PRD): Liver iron
Study 18299450 — Predictive Biomarker (PRD): DDX3Y mRNA
Genes: DDX3Y; DBY
Study 18299450 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 18331634 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 18331634 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 18331634 — Predictive Biomarker (PRD): ADRB3 mRNA
Genes: ADRB3; ADRB3R; B3AR
Study 18331634 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 18331634 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study 18331634 — Predictive Biomarker (PRD): GNB3
Study 18332269 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 18332269 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18332882 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 18334033 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18334033 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18334033 — Predictive Biomarker (PRD): RTL1 mRNA
Genes: RTL1; MAR1; MART1; PEG11
Study 18334537 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 18334676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18334676 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18337339 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18339636 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 18346516 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 18348596 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18353175 — Surrogate Endpoint (SUR): Blood pressure
Study 18378607 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18378607 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18379729 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18379729 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18385168 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 18388178 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 18390837 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 18390837 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 18390837 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18394819 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18402897 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18402897 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18413173 — Surrogate Endpoint (SUR): Blood pressure
Study 18413173 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18413173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18419879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18420097 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 18421079 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18426988 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 18426988 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 18426988 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18436082 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18436120 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18437127 — Surrogate Endpoint (SUR): Blood pressure
Study 18441370 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 18441371 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 18445662 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18445662 — Surrogate Endpoint (SUR): Blood pressure
Study 18452610 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 18452610 — Predictive Biomarker (PRD): RTL1 mRNA
Genes: RTL1; MAR1; MART1; PEG11
Study 18452610 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18452610 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 18456875 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18457580 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18457586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18457586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18471323 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18473686 — Predictive Biomarker (PRD): Tripeptidyl-peptidase I
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study 18474099 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 18477770 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 18477770 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 18477770 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 18480204 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 18482659 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 18495536 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18495536 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18504323 — Surrogate Endpoint (SUR): Blood pressure
Study 18504339 — Surrogate Endpoint (SUR): Serum creatinine
Study 18509084 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 18509084 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18509175 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18514203 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 18519811 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18519811 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 18520231 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study 18523152 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 18523152 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18541828 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18541828 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18544707 — Predictive Biomarker (PRD): EXT2 mRNA
Genes: EXT2
Study 18544707 — Predictive Biomarker (PRD): CDKAL1 mRNA
Genes: CDKAL1
Study 18544707 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 18544707 — Predictive Biomarker (PRD): IGF2BP2 mRNA
Genes: IGF2BP2; IMP2; VICKZ2
Study 18544707 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 18544707 — Predictive Biomarker (PRD): SLC30A8 mRNA
Genes: SLC30A8; ZNT8
Study 18545693 — Surrogate Endpoint (SUR): Blood pressure
Study 18551042 — Predictive Biomarker (PRD): CBR3 mRNA
Genes: CBR3; SDR21C2
Study 18551042 — Predictive Biomarker (PRD): CBR1 mRNA
Genes: CBR1; CBR; CRN; SDR21C1
Study 18554762 — Surrogate Endpoint (SUR): Blood pressure
Study 18554762 — Surrogate Endpoint (SUR): Serum calcium
Study 18559695 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 18559695 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18559696 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18560516 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18572984 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18580170 — Safety Biomarker (SAF): MTHFR
Study 18580170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 18582195 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18582195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18591547 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18591547 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18592321 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18596230 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 18596272 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18596272 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 18596272 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18598891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18612102 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 18612102 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 18615176 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18615176 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18621618 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18625666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18625666 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18625666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18625666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18625762 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18635429 — Surrogate Endpoint (SUR): Serum creatinine
Study 18640325 — Surrogate Endpoint (SUR): Blood pressure
Study 18641094 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18641097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18650451 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 18652942 — Surrogate Endpoint (SUR): Blood pressure
Study 18656877 — Surrogate Endpoint (SUR): Blood pressure
Study 18663426 — Safety Biomarker (SAF): Reactive oxygen species
Study 18668591 — Safety Biomarker (SAF): Interleukin 1
Study 18668591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18668653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18669874 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 18671877 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18671877 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 18671877 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 18671877 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18671877 — Safety Biomarker (SAF): BDNF
Study 18682513 — Surrogate Endpoint (SUR): Blood pressure
Study 18687247 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18687759 — Surrogate Endpoint (SUR): Blood pressure
Study 18693069 — Safety Biomarker (SAF): Human leucocyte antigen
Study 18694338 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 18698342 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18698342 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 18707849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18722008 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 18722008 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 18723429 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 18728159 — Surrogate Endpoint (SUR): Blood pressure
Study 18728159 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18729192 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 18758745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18758745 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 18758745 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 18758745 — Predictive Biomarker (PRD): IL1R1 mRNA
Genes: IL1R1; IL1R; IL1RA; IL1RT1
Study 18758745 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 18758745 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 18758745 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18758745 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 18758745 — Predictive Biomarker (PRD): IKBKB mRNA
Genes: IKBKB; IKKB
Study 18765432 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18769450 — Predictive Biomarker (PRD): BACH2 mRNA
Genes: BACH2
Study 18769450 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18769450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18769450 — Predictive Biomarker (PRD): NFATC2 mRNA
Genes: NFATC2; NFAT1; NFATP
Study 18769450 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18769450 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18771667 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 18776118 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18778241 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18780832 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 18791359 — Surrogate Endpoint (SUR): Bone mineral density
Study 18794207 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18794456 — Predictive Biomarker (PRD): GREB1 mRNA
Genes: GREB1; KIAA0575
Study 18794722 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 18799002 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 18799354 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18805967 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 18806079 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 18812445 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 18824594 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18825363 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 18825363 — Predictive Biomarker (PRD): ADGRE1 mRNA
Genes: ADGRE1; EMR1; TM7LN3
Study 18825363 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18825363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18825363 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18832245 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 18832245 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18832245 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 18838471 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18838477 — Surrogate Endpoint (SUR): Hematologic response
Study 18845370 — Safety Biomarker (SAF): Cystatin C
Genes: CST3