TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7524696 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3555589 — Surrogate Endpoint (SUR): Blood pressure
Study 18187995 — Surrogate Endpoint (SUR): Blood pressure
Study 7794582 — Surrogate Endpoint (SUR): Blood pressure
Study 28276596 — Surrogate Endpoint (SUR): Bone mineral density
Study 26378683 — Surrogate Endpoint (SUR): Blood pressure
Study 9287228 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31413164 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 8682010 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2096405 — Surrogate Endpoint (SUR): Blood pressure
Study 26385957 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 29057795 — Surrogate Endpoint (SUR): Blood pressure
Study 19375884 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16283320 — Surrogate Endpoint (SUR): Bone mineral density
Study 16283320 — Surrogate Endpoint (SUR): Serum calcium
Study 18036453 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17287847 — Surrogate Endpoint (SUR): Blood pressure
Study 12031372 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8810174 — Surrogate Endpoint (SUR): Serum potassium
Study 31461577 — Surrogate Endpoint (SUR): Blood pressure
Study 26398704 — Surrogate Endpoint (SUR): Serum creatinine
Study 21108431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18202666 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18202666 — Surrogate Endpoint (SUR): Blood pressure
Study 18202666 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8862238 — Surrogate Endpoint (SUR): Blood pressure
Study 26472682 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 26472682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26472682 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23747790 — Surrogate Endpoint (SUR): Blood pressure
Study 23628132 — Surrogate Endpoint (SUR): Serum calcium
Study 21342321 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19644396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9205939 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9205939 — Surrogate Endpoint (SUR): Serum creatinine
Study 9205939 — Surrogate Endpoint (SUR): Blood pressure
Study 16305600 — Predictive Biomarker (PRD): ATP1A1 mRNA
Genes: ATP1A1
Study 2194987 — Surrogate Endpoint (SUR): Blood pressure
Study 21999413 — Surrogate Endpoint (SUR): Blood pressure
Study 15075512 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9007492 — Surrogate Endpoint (SUR): Blood pressure
Study 8373274 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3115153 — Surrogate Endpoint (SUR): Blood pressure
Study 19064024 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9100553 — Surrogate Endpoint (SUR): Bone mineral density
Study 9100553 — Surrogate Endpoint (SUR): Serum calcium
Study 27376698 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1936474 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11465967 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8424297 — Surrogate Endpoint (SUR): Blood pressure
Study 30120404 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 27621162 — Surrogate Endpoint (SUR): Blood pressure
Study 25640891 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19082800 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8600180 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 8600180 — Surrogate Endpoint (SUR): Blood pressure
Study 29516305 — Safety Biomarker (SAF): Cytochrome c
Study 22461242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22461242 — Safety Biomarker (SAF): IL-6 and IL-10
Study 20578383 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21262918 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 7816008 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 7816008 — Surrogate Endpoint (SUR): Serum calcium
Study 25413485 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 25413485 — Surrogate Endpoint (SUR): Blood pressure
Study 29632222 — Surrogate Endpoint (SUR): Blood pressure
Study 23742030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7594445 — Surrogate Endpoint (SUR): Blood pressure
Study 7004250 — Surrogate Endpoint (SUR): Blood pressure
Study 10719296 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10719296 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10719296 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10719296 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 3893106 — Surrogate Endpoint (SUR): Serum creatinine
Study 27266340 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10406816 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study 8884862 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30659024 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30659024 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26444853 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 11467638 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10710067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16492297 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 16492297 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10856869 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10856869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10856869 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28829665 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28829665 — Surrogate Endpoint (SUR): Blood pressure
Study 7914235 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25185099 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25185099 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25185099 — Predictive Biomarker (PRD): Hormone receptor
Study 31847602 — Surrogate Endpoint (SUR): Blood pressure
Study 31274244 — Surrogate Endpoint (SUR): Blood pressure
Study 23872824 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16615287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16615287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14571186 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10729391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10729391 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20464599 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 11849659 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21624490 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17608233 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25078374 — Surrogate Endpoint (SUR): Blood pressure
Study 28284167 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26041677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 22833195 — Predictive Biomarker (PRD): CTNNA2 mRNA
Genes: CTNNA2; CAPR
Study 7641736 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2655685 — Surrogate Endpoint (SUR): Blood pressure
Study 19092650 — Surrogate Endpoint (SUR): Blood pressure
Study 17053552 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17053552 — Surrogate Endpoint (SUR): Blood pressure
Study 17053552 — Surrogate Endpoint (SUR): Serum creatinine
Study 2192099 — Surrogate Endpoint (SUR): Blood pressure
Study 457528 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31781694 — Safety Biomarker (SAF): Hyaluronic acid
Study 24220935 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24220935 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28599676 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 25923462 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12624295 — Surrogate Endpoint (SUR): Blood pressure
Study 8656666 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8656666 — Surrogate Endpoint (SUR): Blood pressure
Study 1877363 — Surrogate Endpoint (SUR): Blood pressure
Study 25117302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25117302 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19323930 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19323930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11158043 — Surrogate Endpoint (SUR): Blood pressure
Study 9576193 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 25257259 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 24171985 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21843028 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19661833 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9166835 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11378012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8111807 — Surrogate Endpoint (SUR): Blood pressure
Study 3298405 — Surrogate Endpoint (SUR): Serum creatinine
Study 25500684 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 29676944 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29676944 — Predictive Biomarker (PRD): Hormone receptor
Study 11448906 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11448906 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8596756 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8596756 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8596756 — Surrogate Endpoint (SUR): Serum creatinine
Study 8596756 — Surrogate Endpoint (SUR): Blood pressure
Study 14693625 — Surrogate Endpoint (SUR): Blood pressure
Study 12563568 — Surrogate Endpoint (SUR): Blood pressure
Study 11597291 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25171906 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 20973685 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1307052 — Surrogate Endpoint (SUR): Blood pressure
Study 31005923 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 28843031 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26823294 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17584825 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 16132888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12034024 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8703666 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8703666 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2147175 — Surrogate Endpoint (SUR): Blood pressure
Study 2147175 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2147175 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2147175 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25979300 — Predictive Biomarker (PRD): ANGPTL8 mRNA
Genes: ANGPTL8; C19orf80; RIFL; UNQ599/PRO1185
Study 22852117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15526058 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 29987027 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 27793135 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23327604 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 7564347 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7564347 — Surrogate Endpoint (SUR): Blood pressure
Study 7564347 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23569345 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 23569345 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 23569345 — Safety Biomarker (SAF): Interleukin 1
Study 17892982 — Predictive Biomarker (PRD): FBN1 mRNA
Genes: FBN1; FBN
Study 11474773 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 3260759 — Surrogate Endpoint (SUR): Serum creatinine
Study 29880010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23284036 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 21640089 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18039239 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 9652994 — Surrogate Endpoint (SUR): Bone mineral density
Study 10150434 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31857217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25572878 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 24928083 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 17244785 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17244785 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16286549 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 14600187 — Surrogate Endpoint (SUR): Serum creatinine
Study 16357163 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 16357163 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 16357163 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 9044338 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1526096 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22435937 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22435937 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16259492 — Surrogate Endpoint (SUR): Blood pressure
Study 14742356 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 14742356 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26625506 — Surrogate Endpoint (SUR): Blood pressure
Study 18951296 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10843169 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24337978 — Surrogate Endpoint (SUR): Blood pressure
Study 22395187 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 18399898 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18399898 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12750099 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 12750099 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 12750099 — Predictive Biomarker (PRD): HRC mRNA
Genes: HRC; HCP
Study 10550454 — Surrogate Endpoint (SUR): Bone mineral density
Study 8905799 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 28303364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28303364 — Surrogate Endpoint (SUR): Blood pressure
Study 25209368 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 16492611 — Surrogate Endpoint (SUR): Blood pressure
Study 3578422 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 17932377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17932377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17932377 — Surrogate Endpoint (SUR): Blood pressure
Study 1306606 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30457230 — Safety Biomarker (SAF): Hyaluronic acid
Study 14610474 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 14610474 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 14610474 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8718563 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25882973 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24273968 — Surrogate Endpoint (SUR): Sperm parameters
Study 16839836 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29253747 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study 29253747 — Predictive Biomarker (PRD): TICAM1 mRNA
Genes: TICAM1; PRVTIRB; TRIF
Study 29253747 — Predictive Biomarker (PRD): IRAK1 mRNA
Genes: IRAK1; IRAK
Study 29253747 — Pharmacodynamic Biomarker (PDY): Interferon regulatory factor 3
Genes: IRF3
Study 29253747 — Predictive Biomarker (PRD): IRF7 mRNA
Genes: IRF7
Study 29253747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29253747 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29253747 — Surrogate Endpoint (SUR): Serum creatinine
Study 31356432 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 27129183 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 15664003 — Surrogate Endpoint (SUR): Bone mineral density
Study 6788167 — Surrogate Endpoint (SUR): Blood pressure
Study 24942311 — Surrogate Endpoint (SUR): Blood pressure
Study 1373372 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 26187555 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16700881 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 16700881 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16700881 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16700881 — Surrogate Endpoint (SUR): Blood pressure
Study 10781127 — Surrogate Endpoint (SUR): Blood pressure
Study 1465036 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 6146570 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11792604 — Surrogate Endpoint (SUR): Bone mineral density
Study 1449110 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 23379386 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 23924044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2189027 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2189027 — Surrogate Endpoint (SUR): Blood pressure
Study 31488314 — Predictive Biomarker (PRD): TRIM32 mRNA
Genes: TRIM32; HT2A
Study 30886125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 24282229 — Surrogate Endpoint (SUR): Blood pressure
Study 19143751 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 19143751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19143751 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17695377 — Surrogate Endpoint (SUR): Blood pressure
Study 9613308 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25790022 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 20805297 — Surrogate Endpoint (SUR): Bone mineral density
Study 11115442 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9099188 — Surrogate Endpoint (SUR): Bone mineral density
Study 25071343 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25071343 — Monitoring Biomarker (MOI): HBV DNA
Study 12689976 — Surrogate Endpoint (SUR): Blood pressure
Study 8724709 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 1860094 — Surrogate Endpoint (SUR): Blood pressure
Study 30997967 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27993381 — Surrogate Endpoint (SUR): Total kidney volume
Study 25202068 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 25202068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20879046 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12089368 — Surrogate Endpoint (SUR): Blood pressure
Study 12089368 — Surrogate Endpoint (SUR): Serum creatinine
Study 2565105 — Surrogate Endpoint (SUR): Blood pressure
Study 27515804 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 27515804 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 21806769 — Surrogate Endpoint (SUR): Blood pressure
Study 8496313 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12846772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10843158 — Surrogate Endpoint (SUR): Blood pressure
Study 6391005 — Surrogate Endpoint (SUR): Blood pressure