TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15937294 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 7272161 — Surrogate Endpoint (SUR): Blood pressure
Study 30429050 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26685691 — Safety Biomarker (SAF): Hyaluronic acid
Study 31227278 — Surrogate Endpoint (SUR): Bone mineral density
Study 25710943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25710943 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 25710943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25710943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25710943 — Predictive Biomarker (PRD); Safety Biomarker (SAF): IL1B
Genes: IL1F2; IL-1B; IL1-BETA
Study 16260422 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 9799029 — Surrogate Endpoint (SUR): Blood pressure
Study 7900700 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2793707 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 367713 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29297443 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16483659 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 16304259 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10213219 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26418025 — Surrogate Endpoint (SUR): Blood pressure
Study 26007637 — Predictive Biomarker (PRD): KCNQ2 mRNA
Genes: KCNQ2
Study 11684212 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7833220 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31815661 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21631570 — Safety Biomarker (SAF): Nicotinamide phosphoribosyltransferase
Genes: NAMPT; PBEF; PBEF1
Study 21631570 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21631570 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12661619 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 21386830 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 21386830 — Surrogate Endpoint (SUR): Bone mineral density
Study 21386830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19564877 — Surrogate Endpoint (SUR): Blood pressure
Study 17178091 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 11736720 — Monitoring Biomarker (MOI): HBV DNA
Study 27927936 — Surrogate Endpoint (SUR): Blood pressure
Study 25548848 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 23426761 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21420111 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 9296641 — Surrogate Endpoint (SUR): Blood pressure
Study 9296641 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15262604 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9101427 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9101427 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 8468114 — Surrogate Endpoint (SUR): Serum creatinine
Study 29911495 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29911495 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 2523664 — Surrogate Endpoint (SUR): Blood pressure
Study 27315439 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22051153 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22051153 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17230618 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15039245 — Predictive Biomarker (PRD): COMMD3 mRNA
Genes: COMMD3; BUP; C10orf8
Study 15039245 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11755834 — Surrogate Endpoint (SUR): Blood pressure
Study 31042340 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28387927 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 28387927 — Predictive Biomarker (PRD): Microsatellite instability
Study 14985690 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9185038 — Surrogate Endpoint (SUR): Blood pressure
Study 24893332 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18341596 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8922653 — Surrogate Endpoint (SUR): Bone mineral density
Study 1352717 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3993558 — Surrogate Endpoint (SUR): Blood pressure
Study 10546234 — Surrogate Endpoint (SUR): Bone mineral density
Study 28802789 — Safety Biomarker (SAF): Cytochrome c
Study 21211004 — Predictive Biomarker (PRD): AMPD1 mRNA
Genes: AMPD1
Study 19122556 — Surrogate Endpoint (SUR): Blood pressure
Study 17223209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17223209 — Predictive Biomarker (PRD): APLNR mRNA
Genes: APLNR; AGTRL1; APJ
Study 3202400 — Surrogate Endpoint (SUR): Blood pressure
Study 29167951 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 23146410 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31590967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8069190 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 25162916 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21904641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17942871 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 14506092 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 14506092 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31059974 — Predictive Biomarker (PRD): TK1 mRNA
Genes: TK1
Study 27856267 — Surrogate Endpoint (SUR): Bone mineral density
Study 24642580 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 21748722 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21748722 — Surrogate Endpoint (SUR): Serum calcium
Study 25730649 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 10735784 — Surrogate Endpoint (SUR): Blood pressure
Study 22455412 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 15679722 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8774258 — Surrogate Endpoint (SUR): Blood pressure
Study 18047871 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 1300856 — Surrogate Endpoint (SUR): Blood pressure
Study 31362729 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9880451 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7720346 — Surrogate Endpoint (SUR): Serum creatinine
Study 7720346 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 2187723 — Monitoring Biomarker (MOI): HBV DNA
Study 23077973 — Surrogate Endpoint (SUR): Blood pressure
Study 20693243 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18825368 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17052901 — Surrogate Endpoint (SUR): Serum potassium
Study 15288384 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 15288384 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 21079803 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8993764 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23775007 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 23775007 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 8896099 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 2050831 — Surrogate Endpoint (SUR): Blood pressure
Study 25299501 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 25299501 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16832133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23497032 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 3528612 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29370120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29370120 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 27196148 — Surrogate Endpoint (SUR): Blood pressure
Study 12692753 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12692753 — Surrogate Endpoint (SUR): Blood pressure
Study 10750754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10750754 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8959161 — Safety Biomarker (SAF): Cytochrome c
Study 2933253 — Surrogate Endpoint (SUR): Blood pressure
Study 8260897 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28060360 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28060360 — Surrogate Endpoint (SUR): Blood pressure
Study 23348981 — Safety Biomarker (SAF): Reactive oxygen species
Study 17973947 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 17973947 — Surrogate Endpoint (SUR): Bone mineral density
Study 12862363 — Surrogate Endpoint (SUR): Bone mineral density
Study 6889218 — Surrogate Endpoint (SUR): Blood pressure
Study 20028707 — Surrogate Endpoint (SUR): Blood pressure
Study 10506666 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 26254087 — Surrogate Endpoint (SUR): Blood pressure
Study 18513638 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18513638 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12556736 — Surrogate Endpoint (SUR): Blood pressure
Study 10898419 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1331023 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20520820 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12455077 — Surrogate Endpoint (SUR): Blood pressure
Study 25557316 — Surrogate Endpoint (SUR): Serum testosterone
Study 27902833 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 25804495 — Surrogate Endpoint (SUR): Blood pressure
Study 25804495 — Surrogate Endpoint (SUR): Serum potassium
Study 21389626 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21389626 — Surrogate Endpoint (SUR): Blood pressure
Study 21389626 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 15552163 — Surrogate Endpoint (SUR): Bone mineral density
Study 15257184 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9814456 — Surrogate Endpoint (SUR): Bone mineral density
Study 9814456 — Surrogate Endpoint (SUR): Serum calcium
Study 24621836 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 3240634 — Surrogate Endpoint (SUR): Serum testosterone
Study 3240634 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31621251 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 23305349 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23305349 — Surrogate Endpoint (SUR): Blood pressure
Study 2894980 — Surrogate Endpoint (SUR): Blood pressure
Study 26320403 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6338693 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6338693 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30762895 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 30762895 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21900844 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9708659 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31924513 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25315667 — Surrogate Endpoint (SUR): Blood pressure
Study 9160916 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8105773 — Surrogate Endpoint (SUR): Blood pressure
Study 3114306 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3114306 — Surrogate Endpoint (SUR): Serum testosterone
Study 8623945 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 6378105 — Surrogate Endpoint (SUR): Blood pressure
Study 29373753 — Predictive Biomarker (PRD): TARBP2 mRNA
Genes: TARBP2; TRBP
Study 23106878 — Surrogate Endpoint (SUR): Serum testosterone
Study 19811509 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 18626271 — Surrogate Endpoint (SUR): Blood pressure
Study 16143742 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 31554388 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7850816 — Surrogate Endpoint (SUR): Blood pressure
Study 24377221 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 24377221 — Surrogate Endpoint (SUR): Blood pressure
Study 21278214 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 15542278 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 2258782 — Surrogate Endpoint (SUR): Blood pressure
Study 19615653 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7925510 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7925510 — Surrogate Endpoint (SUR): Blood pressure
Study 2810673 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2810673 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31089256 — Predictive Biomarker (PRD): PRPH2 mRNA
Genes: PRPH2; PRPH; RDS; TSPAN22
Study 12238845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12238845 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26409698 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 24129363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21693504 — Surrogate Endpoint (SUR): Blood pressure
Study 15580194 — Surrogate Endpoint (SUR): Bone mineral density
Study 9201877 — Predictive Biomarker (PRD): PPIH mRNA
Genes: PPIH; CYP20; CYPH
Study 18261537 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18261537 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 18261537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15842584 — Monitoring Biomarker (MOI): HBV DNA
Study 8462363 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8462363 — Surrogate Endpoint (SUR): Serum calcium
Study 26911132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20147968 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20147968 — Surrogate Endpoint (SUR): Blood pressure
Study 9383694 — Surrogate Endpoint (SUR): Bone mineral density
Study 9122864 — Surrogate Endpoint (SUR): Blood pressure
Study 9351684 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8222740 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29617180 — Predictive Biomarker (PRD): TPSG1 mRNA
Genes: TPSG1; PRSS31; TMT
Study 30412147 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 26891754 — Surrogate Endpoint (SUR): Blood pressure
Study 12507361 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 9771950 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 25526495 — Surrogate Endpoint (SUR): Serum sodium
Study 18665360 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15095035 — Surrogate Endpoint (SUR): Bone mineral density
Study 8788313 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 8788313 — Surrogate Endpoint (SUR): Serum calcium
Study 20031834 — Surrogate Endpoint (SUR): Blood pressure
Study 31434552 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24812894 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15939067 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 15939067 — Surrogate Endpoint (SUR): Blood pressure
Study 11788467 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 11788467 — Surrogate Endpoint (SUR): Blood pressure
Study 30893292 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 18047518 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 29308759 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7532763 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31410659 — Surrogate Endpoint (SUR): Serum uric acid
Study 31410659 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28492898 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 2913892 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 27908689 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31804005 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 16652130 — Surrogate Endpoint (SUR): Blood pressure
Study 10207236 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7882472 — Surrogate Endpoint (SUR): Blood pressure
Study 21372490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24835842 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12176948 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 18632210 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 11061779 — Surrogate Endpoint (SUR): Serum calcium
Study 11061779 — Surrogate Endpoint (SUR): Bone mineral density
Study 27933703 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 27933703 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23049087 — Predictive Biomarker (PRD): DTL mRNA
Genes: DTL; CDT2; CDW1; DCAF2; L2DTL; RAMP
Study 23049087 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study 15186955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15186955 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15186955 — Safety Biomarker (SAF): Interleukin 1
Study 9000658 — Surrogate Endpoint (SUR): Serum creatinine
Study 30124473 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26702772 — Predictive Biomarker (PRD): CACNA1G mRNA
Genes: CACNA1G; KIAA1123
Study 26702772 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 26702772 — Predictive Biomarker (PRD): RUNX3 mRNA
Genes: RUNX3; AML2; CBFA3; PEBP2A3
Study 26702772 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 22418243 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 1878587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27134249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24373927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22775078 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31128958 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15940046 — Surrogate Endpoint (SUR): Blood pressure
Study 11899820 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8590154 — Surrogate Endpoint (SUR): Bone mineral density
Study 30970655 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23839583 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16888272 — Surrogate Endpoint (SUR): Blood pressure
Study 8844019 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8844019 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1636624 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31296491 — Surrogate Endpoint (SUR): Pathological complete response
Study 21775563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19957549 — Surrogate Endpoint (SUR): Bone mineral density
Study 15386934 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15386934 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31590930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26424549 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18824930 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7710444 — Surrogate Endpoint (SUR): Blood pressure
Study 29096631 — Surrogate Endpoint (SUR): Blood pressure
Study 20309694 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8891888 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 8891888 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 8891888 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6603074 — Surrogate Endpoint (SUR): Blood pressure
Study 31101732 — Predictive Biomarker (PRD): ADCY10 mRNA
Genes: ADCY10; SAC
Study 16126804 — Surrogate Endpoint (SUR): Serum creatinine
Study 15071015 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8044782 — Pharmacodynamic Biomarker (PDY): DNA topoisomerase I
Genes: TOP1
Study 27816302 — Predictive Biomarker (PRD): ELF4 mRNA
Genes: ELF4; ELFR; MEF
Study 27816302 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24788581 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 17062365 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17062365 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 17062365 — Surrogate Endpoint (SUR): Blood pressure
Study 2124470 — Surrogate Endpoint (SUR): Blood pressure