TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21215201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11139006 — Surrogate Endpoint (SUR): Blood pressure
Study 9105223 — Surrogate Endpoint (SUR): Blood pressure
Study 28495197 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16436132 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29187901 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 29187901 — Monitoring Biomarker (MOI): Cell-free DNA
Study 8895037 — Surrogate Endpoint (SUR): Blood pressure
Study 30610026 — Surrogate Endpoint (SUR): Serum creatinine
Study 29395637 — Predictive Biomarker (PRD): ASPA mRNA
Genes: ASPA; ACY2; ASP
Study 29395637 — Predictive Biomarker (PRD): ITGA2B mRNA
Genes: ITGA2B; GP2B; ITGAB
Study 29395637 — Predictive Biomarker (PRD): PDE4C mRNA
Genes: PDE4C; DPDE1
Study 12163810 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 15606396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11125881 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11125881 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 3180669 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31046812 — Surrogate Endpoint (SUR): Blood pressure
Study 17673219 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17673219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17673219 — Surrogate Endpoint (SUR): Blood pressure
Study 27789938 — Surrogate Endpoint (SUR): Blood pressure
Study 24665995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22586173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11097601 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 31906814 — Surrogate Endpoint (SUR): Blood pressure
Study 28784687 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18577531 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 18577531 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 22115143 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 11581545 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11581545 — Surrogate Endpoint (SUR): Blood pressure
Study 25286455 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31786695 — Predictive Biomarker (PRD): TLR1 mRNA
Genes: TLR1; KIAA0012
Study 31786695 — Predictive Biomarker (PRD): TLR6 mRNA
Genes: TLR6
Study 28295989 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 16581477 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16581477 — Surrogate Endpoint (SUR): Blood pressure
Study 9266878 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 2648152 — Surrogate Endpoint (SUR): Blood pressure
Study 16859579 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26251005 — Surrogate Endpoint (SUR): Blood pressure
Study 22313548 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 12131215 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7010854 — Surrogate Endpoint (SUR): Blood pressure
Study 31390500 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 9040213 — Surrogate Endpoint (SUR): Bone mineral density
Study 7713100 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2455118 — Surrogate Endpoint (SUR): Blood pressure
Study 29329042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27035372 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 16820403 — Predictive Biomarker (PRD): SPAG11B mRNA
Genes: SPAG11B; EP2; HE2
Study 14563968 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 14563968 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 10891434 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27562403 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 8600189 — Surrogate Endpoint (SUR): Blood pressure
Study 20150175 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 15465628 — Predictive Biomarker (PRD): GCSAM mRNA
Genes: GCSAM; GAL; GCET2
Study 11595248 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11595248 — Surrogate Endpoint (SUR): Blood pressure
Study 25925842 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 21756812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21756812 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 21756812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21756812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21756812 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24573743 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24573743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9660024 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1269432 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30797492 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28183232 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 11686827 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9219202 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9219202 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19021008 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study 19021008 — Surrogate Endpoint (SUR): Blood pressure
Study 16640101 — Monitoring Biomarker (MOI): HBV DNA
Study 14559932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11050695 — Surrogate Endpoint (SUR): Blood pressure
Study 15910347 — Surrogate Endpoint (SUR): Blood pressure
Study 30967307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30967307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30967307 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 19245692 — Surrogate Endpoint (SUR): Blood pressure
Study 11772296 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 7930256 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21040626 — Surrogate Endpoint (SUR): Blood pressure
Study 18349061 — Surrogate Endpoint (SUR): Bone mineral density
Study 17703634 — Surrogate Endpoint (SUR): Blood pressure
Study 14987497 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 25651363 — Surrogate Endpoint (SUR): Serum potassium
Study 21315223 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 11131448 — Surrogate Endpoint (SUR): Bone mineral density
Study 8886085 — Safety Biomarker (SAF): Hyaluronic acid
Study 3021443 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3021443 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11475717 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24031 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22878868 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 22878868 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 22878868 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22878868 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 22878868 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 31542756 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 29923005 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29923005 — Safety Biomarker (SAF): BDNF
Study 21147694 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17693890 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9972741 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 26789096 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24161333 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 24161333 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24161333 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19996931 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7030977 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7030977 — Surrogate Endpoint (SUR): Blood pressure
Study 20972878 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 10197489 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 12666963 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22791904 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 22791904 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 15681270 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 29897685 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 25893426 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25893426 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 16537848 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16537848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12773121 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15782318 — Surrogate Endpoint (SUR): Blood pressure
Study 9495568 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9495568 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9495568 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24417987 — Surrogate Endpoint (SUR): Blood pressure
Study 19487960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30476517 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28399118 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 16298650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 2527545 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2527545 — Surrogate Endpoint (SUR): Blood pressure
Study 20360917 — Surrogate Endpoint (SUR): Blood pressure
Study 31586587 — Safety Biomarker (SAF): Reactive oxygen species
Study 28800972 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 6354530 — Surrogate Endpoint (SUR): Blood pressure
Study 28893244 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26802156 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 26802156 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26802156 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 26802156 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17556352 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11965415 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30704524 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 30704524 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 30704524 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study 30704524 — Predictive Biomarker (PRD): miR-145
Genes: MIR145
Study 28598894 — Surrogate Endpoint (SUR): Blood pressure
Study 23942586 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 1582503 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 1582503 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30937964 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 19781847 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 19781847 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 12501132 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9141524 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 20606123 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28929356 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24813581 — Surrogate Endpoint (SUR): Blood pressure
Study 25376730 — Surrogate Endpoint (SUR): Blood pressure
Study 17460095 — Predictive Biomarker (PRD): MENT mRNA
Genes: MENT; C1orf56; UNQ547/PRO1104
Study 17460095 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30309449 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30309449 — Surrogate Endpoint (SUR): Blood pressure
Study 18037095 — Surrogate Endpoint (SUR): Serum creatinine
Study 12383565 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 7581059 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31996195 — Surrogate Endpoint (SUR): Blood pressure
Study 30992081 — Surrogate Endpoint (SUR): Blood pressure
Study 28402324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19950289 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15342614 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15342614 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8042612 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1676239 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 655457 — Surrogate Endpoint (SUR): Blood pressure
Study 28752228 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 20951003 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 2344089 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 29685164 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7752173 — Surrogate Endpoint (SUR): Blood pressure
Study 31302012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31302012 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31302012 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 31302012 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 31302012 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 31302012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31302012 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 26331348 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26331348 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 15238567 — Surrogate Endpoint (SUR): Blood pressure
Study 16434506 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 2073671 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24726027 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 7031085 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 30217943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30217943 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22894939 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17559369 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 16236851 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31957527 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9714109 — Surrogate Endpoint (SUR): Blood pressure
Study 7985708 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7985708 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22805468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21187503 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 2890501 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28265777 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 6843182 — Surrogate Endpoint (SUR): Blood pressure
Study 11303197 — Surrogate Endpoint (SUR): Blood pressure
Study 26334856 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26334856 — Safety Biomarker (SAF): Cardiac troponin T
Genes: TNNT2
Study 8409060 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8409060 — Surrogate Endpoint (SUR): Blood pressure
Study 2875235 — Surrogate Endpoint (SUR): Blood pressure
Study 29681200 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26522081 — Surrogate Endpoint (SUR): Bone mineral density
Study 388396 — Surrogate Endpoint (SUR): Blood pressure
Study 29264988 — Predictive Biomarker (PRD): RAPH1 mRNA
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 23955812 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23955812 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 22211211 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17389757 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 17389757 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17389757 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 9726699 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9726699 — Surrogate Endpoint (SUR): Blood pressure
Study 23953873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23953873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18021879 — Surrogate Endpoint (SUR): Blood pressure
Study 2933951 — Surrogate Endpoint (SUR): Blood pressure
Study 19690954 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11907659 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 27814737 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27814737 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27814737 — Surrogate Endpoint (SUR): Blood pressure
Study 24443804 — Safety Biomarker (SAF): Hyaluronic acid
Study 16038476 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9464212 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 28938966 — Surrogate Endpoint (SUR): Blood pressure
Study 21685187 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 21685187 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 21685187 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 21685187 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 19304862 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 16671337 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 16671337 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9537306 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19687332 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 19687332 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19687332 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 19687332 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15013994 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15013994 — Safety Biomarker (SAF): Interleukin 1
Study 15013994 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2686710 — Surrogate Endpoint (SUR): Blood pressure
Study 7776527 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2157364 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2157364 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26120075 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18836213 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18836213 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1319385 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 3378514 — Surrogate Endpoint (SUR): Blood pressure
Study 19716278 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18549841 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18549841 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26920590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 31565796 — Surrogate Endpoint (SUR): Blood pressure
Study 26153197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26153197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23332327 — Surrogate Endpoint (SUR): Blood pressure
Study 15284344 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31623659 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30198863 — Safety Biomarker (SAF): miR-200a
Genes: MIR200A
Study 30198863 — Pharmacodynamic Biomarker (PDY): miR-132
Genes: MIR132
Study 30198863 — Predictive Biomarker (PRD): miR-485-3p
Genes: MIR485
Study 30198863 — Safety Biomarker (SAF): miR-22
Genes: MIR22
Study 17652214 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 17652214 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1707230 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30101333 — Surrogate Endpoint (SUR): Blood pressure
Study 31989505 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 31989505 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30925953 — Predictive Biomarker (PRD): PDCD5 mRNA
Genes: PDCD5; TFAR19