TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28264648 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 28264723 — Predictive Biomarker (PRD): ANK3 mRNA
Genes: ANK3
Study 28264723 — Predictive Biomarker (PRD): CDKN2B mRNA
Genes: CDKN2B; MTS2
Study 28264723 — Predictive Biomarker (PRD): CACNA1G mRNA
Genes: CACNA1G; KIAA1123
Study 28264723 — Predictive Biomarker (PRD): IGDCC4 mRNA
Genes: IGDCC4; DDM36; KIAA1628; NOPE
Study 28264723 — Predictive Biomarker (PRD); Safety Biomarker (SAF): P4HA3 mRNA
Genes: P4HA3; UNQ711/PRO1374
Study 28264723 — Predictive Biomarker (PRD): ZNF423 mRNA
Genes: ZNF423; KIAA0760; NPHP14; OAZ
Study 28265415 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 28265459 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 28265757 — Predictive Biomarker (PRD): OSCAR mRNA
Genes: OSCAR
Study 28268087 — Surrogate Endpoint (SUR): Blood pressure
Study 28268358 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 28270022 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 28270136 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28270757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28270924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28270924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28270924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28271639 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28274211 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28274211 — Surrogate Endpoint (SUR): Pathological complete response
Study 28274221 — Surrogate Endpoint (SUR): Blood pressure
Study 28274235 — Predictive Biomarker (PRD): PEBP1 mRNA
Genes: PEBP1; PBP; PEBP
Study 28275119 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28275165 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 28275165 — Surrogate Endpoint (SUR): Blood pressure
Study 28275165 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28275176 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 28275176 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28275176 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 28275176 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28275176 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 28275958 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28280103 — Predictive Biomarker (PRD): CYP2C18 mRNA
Genes: CYP2C18
Study 28281183 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 28282271 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28282585 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 28282585 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28283497 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28284916 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 28285070 — Surrogate Endpoint (SUR): Bone mineral density
Study 28285240 — Predictive Biomarker (PRD): TYRO3 mRNA
Genes: TYRO3; BYK; DTK; RSE; SKY; TIF
Study 28286803 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28287157 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 28288572 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28288572 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28288682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28288963 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 28291640 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 28291870 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28291870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28292858 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 28292941 — Predictive Biomarker (PRD): LYPD3 mRNA
Genes: LYPD3; C4.4A; UNQ491/PRO1007
Study 28293424 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 28293424 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28296283 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28298564 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 28298564 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 28300867 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 28300867 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 28301073 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28302137 — Predictive Biomarker (PRD): CREBBP mRNA
Genes: CREBBP; CBP
Study 28302137 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 28302137 — Predictive Biomarker (PRD): KMT2D mRNA
Genes: KMT2D; ALR; MLL2; MLL4
Study 28302137 — Predictive Biomarker (PRD): GNA13 mRNA
Genes: GNA13
Study 28302137 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28302137 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 28303154 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 28306749 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28314691 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28314691 — Predictive Biomarker (PRD): Hormone receptor
Study 28314833 — Surrogate Endpoint (SUR): Blood pressure
Study 28318100 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 28319446 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28319446 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 28319597 — Surrogate Endpoint (SUR): Blood pressure
Study 28321002 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 28321002 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28321003 — Predictive Biomarker (PRD): MPG mRNA
Genes: MPG; AAG; ANPG; MID1
Study 28321003 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 28322082 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study 28323960 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28323960 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 28323960 — Surrogate Endpoint (SUR): Serum calcium
Study 28323970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28323970 — Predictive Biomarker (PRD): CXCL2 mRNA
Genes: CXCL2; GRO2; GROB; MIP2A; SCYB2
Study 28323970 — Predictive Biomarker (PRD): DUSP1 mRNA
Genes: DUSP1; CL100; MKP1; PTPN10; VH1
Study 28323970 — Predictive Biomarker (PRD): GAS7 mRNA
Genes: GAS7; KIAA0394
Study 28323970 — Predictive Biomarker (PRD): TXNIP mRNA
Genes: TXNIP; VDUP1
Study 28323970 — Predictive Biomarker (PRD): ID3 mRNA
Genes: ID3; 1R21; BHLHB25; HEIR1
Study 28323970 — Predictive Biomarker (PRD): TWIST1 mRNA
Genes: TWIST1; BHLHA38; TWIST
Study 28323999 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28323999 — Surrogate Endpoint (SUR): Blood pressure
Study 28324042 — Safety Biomarker (SAF): Interleukin 1
Study 28324042 — Surrogate Endpoint (SUR): Blood pressure
Study 28324749 — Predictive Biomarker (PRD): MDM2
Genes: HDM2; MGC5370
Study 28324749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 28324749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 28325857 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28325857 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28326189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28326189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28327462 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28327908 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28327908 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 28327908 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 28327908 — Predictive Biomarker (PRD): Microsatellite instability
Study 28327988 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 28329053 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 28329286 — Predictive Biomarker (PRD): OAS1 mRNA
Genes: OAS1; OIAS
Study 28329286 — Predictive Biomarker (PRD): ISG15 mRNA
Genes: ISG15; G1P2; UCRP
Study 28329286 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28329286 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 28330462 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 28330462 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 28330670 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 28331623 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 28333699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28334685 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28335733 — Safety Biomarker (SAF): Reactive oxygen species
Study 28339149 — Safety Biomarker (SAF): Sodium/hydrogen exchanger 3
Genes: SLC9A3; NHE3
Study 28341957 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28343236 — Surrogate Endpoint (SUR): Serum creatinine
Study 28345157 — Monitoring Biomarker (MOI): HBV DNA
Study 28346229 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 28347290 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 28347290 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28348181 — Surrogate Endpoint (SUR): Serum calcium
Study 28349167 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28357727 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28358734 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28358734 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 28359318 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28359411 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 28360015 — Pharmacodynamic Biomarker (PDY): DNA topoisomerase I
Genes: TOP1
Study 28360242 — Surrogate Endpoint (SUR): Blood pressure
Study 28361468 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 28363153 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 28364381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28365204 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 28367426 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 28368743 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28369553 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 28370090 — Surrogate Endpoint (SUR): Serum creatinine
Study 28370350 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 28371297 — Predictive Biomarker (PRD): PRG4 mRNA
Genes: PRG4; MSF; SZP
Study 28371297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28372865 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 28373005 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28373005 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28373005 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 28373007 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 28373069 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 28373262 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 28373269 — Surrogate Endpoint (SUR): Blood pressure
Study 28374214 — Surrogate Endpoint (SUR): Blood pressure
Study 28374214 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28374496 — Monitoring Biomarker (MOI): HBV DNA
Study 28375658 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28376109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28376799 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28378544 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 28378561 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28378918 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28378918 — Surrogate Endpoint (SUR): Blood pressure
Study 28379401 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28379580 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28379580 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28379580 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28380308 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 28381130 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 28383677 — Predictive Biomarker (PRD): SULT1A3 mRNA
Genes: SULT1A3; STM
Study 28385065 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 28385065 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28385306 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study 28388260 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28388657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28388657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28388956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28389304 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28391235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28391235 — Monitoring Biomarker (MOI): Procalcitonin
Study 28391235 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28391894 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 28395671 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28397471 — Safety Biomarker (SAF): MTHFR
Study 28397471 — Surrogate Endpoint (SUR): Blood pressure
Study 28397698 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28398341 — Predictive Biomarker (PRD): CACNA1C mRNA
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 28399804 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 28399815 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28399931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28402487 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28403055 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 28403119 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28404690 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 28405470 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28405470 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28406934 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study 28406940 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28407138 — Surrogate Endpoint (SUR): Serum calcium
Study 28407216 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 28407492 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28408140 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 28408140 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28408140 — Predictive Biomarker (PRD): PER2 mRNA
Genes: PER2; KIAA0347
Study 28408140 — Predictive Biomarker (PRD): GPX4 mRNA
Genes: GPX4
Study 28408140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28408434 — Surrogate Endpoint (SUR): Blood pressure
Study 28408462 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 28408462 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28408615 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 28409004 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28409297 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 28409328 — Surrogate Endpoint (SUR): Hematologic response
Study 28409730 — Predictive Biomarker (PRD): EEF1A2 mRNA
Genes: EEF1A2; EEF1AL; STN
Study 28410341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28410911 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28411282 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 28411282 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28411282 — Predictive Biomarker (PRD): PPP3CA mRNA
Genes: PPP3CA; CALNA; CNA
Study 28413427 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 28414029 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28416015 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28416813 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28416813 — Safety Biomarker (SAF): BDNF
Study 28417284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28417296 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28419237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28420362 — Surrogate Endpoint (SUR): Blood pressure
Study 28420419 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 28420429 — Predictive Biomarker (PRD): DEPTOR mRNA
Genes: DEPTOR; DEPDC6
Study 28420429 — Predictive Biomarker (PRD): PAX5 mRNA
Genes: PAX5
Study 28420429 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 28420429 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study 28420429 — Predictive Biomarker (PRD): miR-135b
Genes: MIR135B
Study 28422751 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28422751 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 28422758 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28422758 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28422758 — Predictive Biomarker (PRD): Microsatellite instability
Study 28423296 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28423296 — Surrogate Endpoint (SUR): Hematologic response
Study 28424071 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 28424891 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 28426811 — Monitoring Biomarker (MOI): Procalcitonin
Study 28427434 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 28427434 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 28427434 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 28427434 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 28427434 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 28427434 — Predictive Biomarker (PRD): CD6 mRNA
Genes: CD6
Study 28427434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28427434 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28427434 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 28428165 — Predictive Biomarker (PRD): KCNIP3 mRNA
Genes: KCNIP3; CSEN; DREAM; KCHIP3
Study 28428882 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28428884 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 28429083 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28431564 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 28431663 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 28433924 — Predictive Biomarker (PRD): FMO3 mRNA
Genes: FMO3
Study 28434702 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 28436937 — Predictive Biomarker (PRD): ALPL mRNA
Genes: ALPL
Study 28436937 — Surrogate Endpoint (SUR): Bone mineral density
Study 28437380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28437488 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 28437668 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 28438154 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28438154 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28439092 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 28439092 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 28439879 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1