TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20180805 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20180805 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20184783 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20188071 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 20188071 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 20188202 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 20188504 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20194866 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 20200024 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20200024 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20206456 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20206456 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20208057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 20208057 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 20210522 — Predictive Biomarker (PRD): DROSHA mRNA
Genes: DROSHA; RN3; RNASE3L; RNASEN
Study 20210645 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20210645 — Predictive Biomarker (PRD): CXCR5 mRNA
Genes: CXCR5; BLR1; MDR15
Study 20210645 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20210645 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20214479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20214479 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 20214479 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 20214479 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20214527 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20214798 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 20219965 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 20221623 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 20225395 — Surrogate Endpoint (SUR): Blood pressure
Study 20225395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20228610 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 20228610 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 20233136 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20233444 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20233444 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 20233444 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 20233444 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 20233444 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 20233444 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 20233976 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 20236700 — Surrogate Endpoint (SUR): Blood pressure
Study 20298558 — Surrogate Endpoint (SUR): Blood pressure
Study 20298558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20298564 — Surrogate Endpoint (SUR): Blood pressure
Study 20298923 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20299634 — Monitoring Biomarker (MOI): Procalcitonin
Study 20299634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20307398 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20335221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 20335221 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20339536 — Predictive Biomarker (PRD): CLMN mRNA
Genes: CLMN; KIAA1188
Study 20339536 — Predictive Biomarker (PRD): APOC1 mRNA
Genes: APOC1
Study 20339536 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 20345222 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 20347684 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 20350136 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20350136 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20350190 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20350302 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 20350831 — Predictive Biomarker (PRD): OPA3 mRNA
Genes: OPA3
Study 20354183 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 20362723 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20368649 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20369375 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20370777 — Surrogate Endpoint (SUR): Blood pressure
Study 20374273 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 20374273 — Predictive Biomarker (PRD): Liver iron
Study 20375178 — Predictive Biomarker (PRD): AQP1 mRNA
Genes: AQP1; CHIP28
Study 20375178 — Predictive Biomarker (PRD): PLIN2 mRNA
Genes: PLIN2; ADFP
Study 20375733 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 20378407 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 20378559 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20378927 — Surrogate Endpoint (SUR): Serum testosterone
Study 20380712 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 20382691 — Safety Biomarker (SAF): Reactive oxygen species
Study 20383216 — Predictive Biomarker (PRD): BMF mRNA
Genes: BMF
Study 20384962 — Monitoring Biomarker (MOI): HBV DNA
Study 20390419 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20390419 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 20391423 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 20395557 — Predictive Biomarker (PRD): SMAD3 mRNA
Genes: SMAD3; MADH3
Study 20395557 — Predictive Biomarker (PRD): HMGA2 mRNA
Genes: HMGA2; HMGIC
Study 20395557 — Predictive Biomarker (PRD): ACTA2 mRNA
Genes: ACTA2; ACTSA; ACTVS; GIG46
Study 20395557 — Predictive Biomarker (PRD): S100A4 mRNA
Genes: S100A4; CAPL; MTS1
Study 20395557 — Predictive Biomarker (PRD): SFTPC mRNA
Genes: SFTPC; SFTP2
Study 20400682 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 20400682 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20400682 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20406267 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 20408846 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 20410100 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 20410100 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 20410100 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study 20410100 — Predictive Biomarker (PRD): MSR1 mRNA
Genes: MSR1; SCARA1
Study 20413039 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20413436 — Predictive Biomarker (PRD): PKHD1 mRNA
Genes: PKHD1; FCYT; TIGM1
Study 20413658 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 20413658 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 20413687 — Predictive Biomarker (PRD): DHODH mRNA
Genes: DHODH
Study 20413733 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 20413733 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 20418798 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20420675 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20420675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 20421061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20421061 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20421061 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20421452 — Predictive Biomarker (PRD): Liver iron
Study 20421455 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 20421455 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 20422738 — Surrogate Endpoint (SUR): Blood pressure
Study 20424554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20424554 — Safety Biomarker (SAF): IL-6 and IL-10
Study 20427509 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 20427701 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 20429821 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20430469 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20430905 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20431360 — Surrogate Endpoint (SUR): Blood pressure
Study 20432813 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 20432813 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20433539 — Surrogate Endpoint (SUR): Blood pressure
Study 20433546 — Surrogate Endpoint (SUR): Blood pressure
Study 20435200 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20435659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20439622 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 20439622 — Surrogate Endpoint (SUR): Bone mineral density
Study 20439622 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20442368 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 20442368 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 20442368 — Predictive Biomarker (PRD): CD96 mRNA
Genes: CD96
Study 20442368 — Predictive Biomarker (PRD): SNRPN mRNA
Genes: SNRPN; HCERN3; SMN
Study 20442368 — Predictive Biomarker (PRD): INSR mRNA
Genes: INSR
Study 20442368 — Predictive Biomarker (PRD): IRS2 mRNA
Genes: IRS2
Study 20442368 — Predictive Biomarker (PRD): PRKAA1 mRNA
Genes: PRKAA1; AMPK1
Study 20442368 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20442365 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20442365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20442365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20444270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20446946 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 20446946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20446946 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20447528 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 20447528 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20448073 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20448073 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 20448094 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20457766 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20457766 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20457975 — Surrogate Endpoint (SUR): Blood pressure
Study 20458050 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20458050 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20458050 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 20458050 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 20458532 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 20461780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20463041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20463041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20463041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20466783 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20471725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20471725 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 20472746 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20472746 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20478057 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20478057 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20484443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20484485 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20487048 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 20489056 — Predictive Biomarker (PRD): AIRE mRNA
Genes: AIRE; APECED
Study 20489620 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 20489620 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 20491780 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 20501469 — Surrogate Endpoint (SUR): Sperm parameters
Study 20507945 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20510210 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20511445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20511662 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 20519658 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 20519658 — Surrogate Endpoint (SUR): Blood pressure
Study 20519661 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20521331 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 20524979 — Predictive Biomarker (PRD): LTBP1 mRNA
Genes: LTBP1
Study 20528299 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 20529243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20529243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20529243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20530034 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20530034 — Surrogate Endpoint (SUR): Blood pressure
Study 20530034 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 20530048 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 20534736 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 20538956 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20545713 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20546561 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20547978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20547978 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20547978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20550691 — Surrogate Endpoint (SUR): Bone mineral density
Study 20550701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20550701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20553600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20557308 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 20558556 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20559034 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20560883 — Surrogate Endpoint (SUR): Blood pressure
Study 20562120 — Surrogate Endpoint (SUR): Blood pressure
Study 20564750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20564750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20566896 — Surrogate Endpoint (SUR): Serum creatinine
Study 20573151 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 20581689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20581689 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20585012 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 20585012 — Surrogate Endpoint (SUR): Blood pressure
Study 20597081 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 20597081 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20598843 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 20599337 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20605360 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 20608766 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20609468 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 20609468 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 20609706 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20616163 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 20620717 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20625116 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 20625116 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 20625390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20627920 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20630061 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 20630061 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 20630061 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 20633428 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 20634483 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20634719 — Surrogate Endpoint (SUR): Blood pressure
Study 20634785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20634785 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20638196 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 20647561 — Surrogate Endpoint (SUR): Serum creatinine
Study 20650435 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 20650435 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20650871 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20651274 — Surrogate Endpoint (SUR): Blood pressure
Study 20653948 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 20657770 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20657770 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 20658481 — Predictive Biomarker (PRD): SFTPC mRNA
Genes: SFTPC; SFTP2
Study 20660053 — Surrogate Endpoint (SUR): Blood pressure
Study 20660788 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20660788 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 20661680 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20667078 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20667078 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 20667078 — Predictive Biomarker (PRD): APOA2 mRNA
Genes: APOA2
Study 20667078 — Predictive Biomarker (PRD): PPIA mRNA
Genes: PPIA; CYPA
Study 20667078 — Predictive Biomarker (PRD): IGFBP4 mRNA
Genes: IGFBP4; IBP4
Study 20668228 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 20671118 — Predictive Biomarker (PRD): PSMB9 mRNA
Genes: PSMB9; LMP2; PSMB6i; RING12
Study 20671408 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20672318 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20677256 — Predictive Biomarker (PRD): Liver iron
Study 20685491 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 20687947 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20687947 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20688740 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 20698927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20705799 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20707601 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20709820 — Predictive Biomarker (PRD): BICD1 mRNA
Genes: BICD1
Study 20713962 — Surrogate Endpoint (SUR): Bone mineral density