TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02946372 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study NCT03866993 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04282499 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01237236 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT01393639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00970502 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00970502 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02576574 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02076035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02076035 — Safety Biomarker (SAF): Interleukin 1
Study NCT03631134 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00704288 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00704288 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00704288 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT00662051 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00662051 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT00662051 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00566228 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01627249 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01627249 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01098279 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04680429 — Predictive Biomarker (PRD): DHODH mRNA
Genes: DHODH
Study NCT00532168 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03288987 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00519480 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03836859 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT00905905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00117260 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03932565 — Predictive Biomarker (PRD): IL7 mRNA
Genes: IL7
Study NCT03932565 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study NCT03932565 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT01947881 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01947881 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02306590 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT01301365 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00262834 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT00842543 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study NCT03482752 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01883284 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01883284 — Predictive Biomarker (PRD): SCGB1A1 mRNA
Genes: SCGB1A1; CC10; CCSP; UGB
Study NCT01883284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study NCT01883284 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study NCT03082092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00709163 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00709163 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04344951 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02323568 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02495766 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04481685 — Predictive Biomarker (PRD): MAPKAPK2 mRNA
Genes: MAPKAPK2
Study NCT01826591 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study NCT01826591 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study NCT02338050 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT01315470 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT02869217 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00618657 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02704650 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT02704650 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT03697694 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03658213 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03658213 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00407537 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00145379 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02711306 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01241643 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00134199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00134199 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03526900 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03526900 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02225834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01389037 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03870399 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03870399 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00388804 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT00388804 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT03599947 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00269854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02274740 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04445298 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT01199835 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02366143 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01870726 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03024944 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01149122 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00043069 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03941626 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study NCT03116139 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02161068 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT04131816 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00005089 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01731600 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT01439867 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01439867 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT00216151 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02742727 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT01211301 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01483144 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT03997487 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT01703962 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT01703962 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study NCT04232904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02302677 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study NCT03348644 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT00787306 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02738645 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04539444 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02506556 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02506556 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02371603 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT04329572 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00847626 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00877929 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01953445 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01953445 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01953445 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04076228 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04279249 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04279249 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04279249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00999739 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00082914 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00531336 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00531336 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00538772 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04374240 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00823082 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT06528119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03117660 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00898833 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01192308 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01020721 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study NCT04456075 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03805776 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03600415 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00930345 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02338128 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT01061099 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02656589 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00813722 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03668145 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03668145 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT02532218 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04327466 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study NCT02855580 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT04462367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04462367 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04462367 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04386694 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04544462 — Predictive Biomarker (PRD): ANXA5 mRNA
Genes: ANXA5; ANX5; ENX2; PP4
Study NCT02361853 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT02361853 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT04360837 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01647945 — Predictive Biomarker (PRD): BMPR2 mRNA
Genes: BMPR2; PPH1
Study NCT02883036 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02883036 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01536080 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT02236871 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02165553 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03963648 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00043953 — Predictive Biomarker (PRD): INVS mRNA
Genes: INVS; INV; NPHP2
Study NCT03878329 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04852666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05793203 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study NCT05793203 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT06545461 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01154140 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00075777 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT01485549 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT01968213 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03267680 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT02588872 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04089189 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02219958 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03906370 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study NCT02449538 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02449538 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02876042 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06326073 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT03429426 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03627403 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT03843918 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT03050190 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04214353 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01377246 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT03658447 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03658447 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03488277 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00932867 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04936022 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00391950 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02243904 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04383912 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT04383912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02282813 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT00011934 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01827267 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04578067 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03016351 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02149238 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02352948 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02352948 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02352948 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03362554 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study NCT04817280 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02900768 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02591654 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT03146520 — Predictive Biomarker (PRD): SDC2 mRNA
Genes: SDC2; HSPG1
Study NCT01456312 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01893489 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03481361 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00671229 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study NCT02061878 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01732367 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01396538 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00994643 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01465815 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03735966 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03379025 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT04500886 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02189512 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT01566539 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT00386529 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01529489 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01466972 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03807479 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03807479 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01218152 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01218152 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01218152 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT02406170 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03192345 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03428308 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02858570 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02858570 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study NCT03046264 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03956017 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03808506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03542513 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT04027959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02178930 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01810939 — Surrogate Endpoint (SUR): Serum potassium
Study NCT03694834 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03694834 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT02688985 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01648153 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT03782753 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT04312347 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01545947 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study NCT03102164 — Predictive Biomarker (PRD): CKM mRNA
Genes: CKM; CKMM
Study NCT03102164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT00889031 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT03453697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03453697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03453697 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT03453697 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT03453697 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03453697 — Safety Biomarker (SAF): Interleukin 1
Study NCT03453697 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT03453697 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT02565524 — Predictive Biomarker (PRD): NRXN1 mRNA
Genes: NRXN1
Study NCT02565524 — Predictive Biomarker (PRD): UPF3B mRNA
Genes: UPF3B; RENT3B; UPF3X
Study NCT00787527 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT03214770 — Surrogate Endpoint (SUR): Bacterial count
Study NCT04576208 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03853551 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03853551 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03845270 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL