TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24643920 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19224159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12149668 — Surrogate Endpoint (SUR): Blood pressure
Study 31669329 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 31669329 — Predictive Biomarker (PRD): ETV5 mRNA
Genes: ETV5; ERM
Study 28552710 — Surrogate Endpoint (SUR): Serum testosterone
Study 15649674 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 7548266 — Surrogate Endpoint (SUR): Blood pressure
Study 7604800 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7604800 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20875945 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 18363889 — Predictive Biomarker (PRD): ADIPOR2 mRNA
Genes: ADIPOR2; PAQR2
Study 12941041 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8427238 — Surrogate Endpoint (SUR): Blood pressure
Study 16247428 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16247428 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16717297 — Surrogate Endpoint (SUR): Blood pressure
Study 15058375 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 27916398 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 8061848 — Surrogate Endpoint (SUR): Blood pressure
Study 30304326 — Surrogate Endpoint (SUR): Blood pressure
Study 29210627 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23589771 — Surrogate Endpoint (SUR): Blood pressure
Study 21525866 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21525866 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 31584766 — Surrogate Endpoint (SUR): Blood pressure
Study 23419459 — Predictive Biomarker (PRD): P2RX2 mRNA
Genes: P2RX2; P2X2
Study 23419459 — Predictive Biomarker (PRD): P2RX1 mRNA
Genes: P2RX1; P2X1
Study 22275250 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 16377699 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29228087 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22382633 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 28584014 — Surrogate Endpoint (SUR): Blood pressure
Study 21340560 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10371376 — Surrogate Endpoint (SUR): Blood pressure
Study 7759224 — Surrogate Endpoint (SUR): Blood pressure
Study 30987577 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21390978 — Surrogate Endpoint (SUR): Blood pressure
Study 9385493 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 9385493 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 21599896 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 22879633 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9709932 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 11973191 — Surrogate Endpoint (SUR): Blood pressure
Study 9465848 — Surrogate Endpoint (SUR): Blood pressure
Study 9465848 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2118272 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18946878 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7043494 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 31118157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31118157 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31118157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23281216 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30074872 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 30074872 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 30074872 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 25802309 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 16369855 — Monitoring Biomarker (MOI): Procalcitonin
Study 12399736 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 27678425 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11901288 — Surrogate Endpoint (SUR): Blood pressure
Study 10155349 — Surrogate Endpoint (SUR): Blood pressure
Study 10155349 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 717750 — Surrogate Endpoint (SUR): Blood pressure
Study 31354147 — Surrogate Endpoint (SUR): Blood pressure
Study 17256759 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 9110940 — Predictive Biomarker (PRD): VIT mRNA
Genes: VIT; UNQ647/PRO1277
Study 31773582 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 30810457 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 25123196 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 27793072 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12417537 — Surrogate Endpoint (SUR): Blood pressure
Study 17472024 — Surrogate Endpoint (SUR): Blood pressure
Study 26590495 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 17186332 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31992445 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 30334631 — Surrogate Endpoint (SUR): Serum creatinine
Study 21061562 — Surrogate Endpoint (SUR): Blood pressure
Study 7615269 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 25380152 — Surrogate Endpoint (SUR): Blood pressure
Study 25380152 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11673080 — Safety Biomarker (SAF): Hypoxanthine-guanine phosphoribosyltransferase
Genes: HPRT1; HPRT
Study 8988721 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 27895474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27895474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11850269 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10516938 — Surrogate Endpoint (SUR): Blood pressure
Study 10516938 — Surrogate Endpoint (SUR): Serum testosterone
Study 30073390 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30073390 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 31634295 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31634295 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31634295 — Safety Biomarker (SAF): BDNF
Study 31634295 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10428106 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7484866 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19238303 — Surrogate Endpoint (SUR): Bone mineral density
Study 25599735 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25599735 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23917392 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 18638309 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18638309 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 18638309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18638309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7604809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7604809 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31196132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25232714 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25232714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7972649 — Surrogate Endpoint (SUR): Blood pressure
Study 28600210 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 28600210 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9786563 — Surrogate Endpoint (SUR): Blood pressure
Study 2845188 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30919899 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30919899 — Surrogate Endpoint (SUR): Blood pressure
Study 23764385 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 21343159 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17609296 — Surrogate Endpoint (SUR): Serum testosterone
Study 8547097 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21838784 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21838784 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 18395908 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 11214351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11214351 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 8626351 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 1601510 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 1601510 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1601510 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 20009917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20009917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20009917 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20009917 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20009917 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20009917 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1650015 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6345596 — Surrogate Endpoint (SUR): Blood pressure
Study 23203821 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 26205311 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 7943770 — Surrogate Endpoint (SUR): Blood pressure
Study 17635246 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11999236 — Surrogate Endpoint (SUR): Blood pressure
Study 204971 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 24696226 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25122429 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17126073 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17126073 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15131468 — Monitoring Biomarker (MOI): HBV DNA
Study 7961258 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 31920016 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 12712779 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 1424410 — Surrogate Endpoint (SUR): Blood pressure
Study 30291012 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30291012 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 30291012 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 30291012 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18158708 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18158708 — Surrogate Endpoint (SUR): Blood pressure
Study 11808977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24410993 — Surrogate Endpoint (SUR): Blood pressure
Study 26912161 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 26912161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26912161 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26912161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14997024 — Safety Biomarker (SAF): Reactive oxygen species
Study 14997024 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10664935 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 6442713 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 22494567 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19578132 — Surrogate Endpoint (SUR): Serum testosterone
Study 19578132 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19578132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11788107 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11788107 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7701577 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 7701577 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29198191 — Surrogate Endpoint (SUR): Blood pressure
Study 8888665 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1651213 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 6173522 — Surrogate Endpoint (SUR): Blood pressure
Study 31838486 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 11322056 — Surrogate Endpoint (SUR): Blood pressure
Study 31548616 — Surrogate Endpoint (SUR): Blood pressure
Study 16840514 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 16840514 — Safety Biomarker (SAF): Reactive oxygen species
Study 31402562 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23640303 — Surrogate Endpoint (SUR): Blood pressure
Study 10843163 — Surrogate Endpoint (SUR): Bone mineral density
Study 25204191 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 25204191 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20976066 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 31825075 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 26035033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19265788 — Surrogate Endpoint (SUR): Blood pressure
Study 25824586 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 2153728 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24470392 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 22172440 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11976562 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21037433 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1726199 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 27734104 — Predictive Biomarker (PRD): PNPLA2 mRNA
Genes: PNPLA2; ATGL; FP17548
Study 27734104 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 27734104 — Predictive Biomarker (PRD): ABHD5 mRNA
Genes: ABHD5; NCIE2; CGI-58
Study 27213436 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20852275 — Surrogate Endpoint (SUR): Blood pressure
Study 15227557 — Surrogate Endpoint (SUR): Blood pressure
Study 2520297 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 31246878 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 28402191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25432966 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 17456523 — Surrogate Endpoint (SUR): Bone mineral density
Study 28225297 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 16146698 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23850491 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 19699049 — Surrogate Endpoint (SUR): Blood pressure
Study 10029341 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 8743187 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1662562 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1662562 — Surrogate Endpoint (SUR): Blood pressure
Study 27919965 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24838177 — Surrogate Endpoint (SUR): Serum creatinine
Study 26989846 — Surrogate Endpoint (SUR): Blood pressure
Study 17959080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12073203 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9647875 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 22455355 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 18240258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18496993 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 12860867 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 12860867 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11818424 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10959382 — Surrogate Endpoint (SUR): Blood pressure
Study 9000839 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26078579 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26078579 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26078579 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21747047 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21747047 — Surrogate Endpoint (SUR): Blood pressure
Study 15475021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11402958 — Surrogate Endpoint (SUR): Blood pressure
Study 25943992 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25943992 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25943992 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 20949349 — Surrogate Endpoint (SUR): Blood pressure
Study 18187617 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19923550 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15217656 — Surrogate Endpoint (SUR): Blood pressure
Study 2571295 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 180192 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31538913 — Safety Biomarker (SAF): Hyaluronic acid
Study 31177276 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 17001567 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 10661479 — Surrogate Endpoint (SUR): Blood pressure
Study 27523186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27523186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15949922 — Surrogate Endpoint (SUR): Blood pressure
Study 10223267 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28166861 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 28166861 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 21675876 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16925377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8504495 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20070250 — Surrogate Endpoint (SUR): Blood pressure
Study 20070250 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12832372 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 31918739 — Predictive Biomarker (PRD): OSR1 mRNA
Genes: OSR1; ODD
Study 28905172 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28905172 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25752889 — Surrogate Endpoint (SUR): Blood pressure
Study 11505744 — Surrogate Endpoint (SUR): Blood pressure
Study 7957511 — Surrogate Endpoint (SUR): Blood pressure
Study 16324916 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16324916 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16324916 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 16324916 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7607719 — Surrogate Endpoint (SUR): Blood pressure
Study 20073999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7995011 — Surrogate Endpoint (SUR): Blood pressure
Study 22212269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22212269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22212269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22212269 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19558539 — Surrogate Endpoint (SUR): Blood pressure