TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11049977 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30449625 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16883263 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3270665 — Surrogate Endpoint (SUR): Probing pocket depth
Study 1232533 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 16846517 — Surrogate Endpoint (SUR): Blood pressure
Study 20797475 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20797475 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26073395 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26073395 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18279770 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25890673 — Surrogate Endpoint (SUR): Serum creatinine
Study 25890673 — Surrogate Endpoint (SUR): Bone mineral density
Study 28664912 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 28664912 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28664912 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 28664912 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 28664912 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 23447519 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23447519 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 21374656 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 29410180 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29410180 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30099769 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 8429694 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8429694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30517236 — Surrogate Endpoint (SUR): Blood pressure
Study 20534752 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 12106834 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29872264 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 25175696 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17767803 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12103457 — Surrogate Endpoint (SUR): Blood pressure
Study 2649632 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 2649632 — Surrogate Endpoint (SUR): Serum phosphate
Study 14514648 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 9625405 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16255837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16255837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11552710 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 11552710 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 31639790 — Surrogate Endpoint (SUR): Serum creatinine
Study 31639790 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21654719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21654719 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18475154 — Surrogate Endpoint (SUR): Blood pressure
Study 21757893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21757893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21757893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15149875 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 15149875 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15149875 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8204472 — Surrogate Endpoint (SUR): Serum creatinine
Study 29184167 — Predictive Biomarker (PRD): NEB mRNA
Genes: NEB
Study 29184167 — Surrogate Endpoint (SUR): Blood pressure
Study 29184167 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25403327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25403327 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 25403327 — Predictive Biomarker (PRD): ADGRE1 mRNA
Genes: ADGRE1; EMR1; TM7LN3
Study 25403327 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17559750 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2745320 — Surrogate Endpoint (SUR): Blood pressure
Study 22594233 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12218231 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 9856368 — Surrogate Endpoint (SUR): Blood pressure
Study 2133226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24197772 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20082737 — Surrogate Endpoint (SUR): Blood pressure
Study 31473172 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 29882843 — Surrogate Endpoint (SUR): Blood pressure
Study 20979906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12147929 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12147929 — Surrogate Endpoint (SUR): Blood pressure
Study 10358862 — Surrogate Endpoint (SUR): Blood pressure
Study 1782973 — Predictive Biomarker (PRD): VEZF1 mRNA
Genes: VEZF1; DB1; ZNF161
Study 23715753 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31254718 — Surrogate Endpoint (SUR): Blood pressure
Study 2887186 — Surrogate Endpoint (SUR): Blood pressure
Study 8201963 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2906873 — Surrogate Endpoint (SUR): Blood pressure
Study 25506778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25506778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21761129 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 18320559 — Safety Biomarker (SAF): DRD3
Study 3519694 — Surrogate Endpoint (SUR): Blood pressure
Study 30557404 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 22490477 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 937076 — Surrogate Endpoint (SUR): Serum potassium
Study 28157728 — Safety Biomarker (SAF): Hyaluronic acid
Study 27009270 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 16142873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30571192 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30571192 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23710734 — Predictive Biomarker (PRD): BOC mRNA
Genes: BOC; UNQ604/PRO1190
Study 25361222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25361222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26095784 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16899031 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 7956627 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 31230825 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31230825 — Surrogate Endpoint (SUR): Serum potassium
Study 17890465 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26010368 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 21830080 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 19575270 — Surrogate Endpoint (SUR): Blood pressure
Study 26911532 — Surrogate Endpoint (SUR): Blood pressure
Study 17914251 — Surrogate Endpoint (SUR): Serum calcium
Study 16981274 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 12604410 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 3924425 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 3924425 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16136771 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10599797 — Surrogate Endpoint (SUR): Blood pressure
Study 7275464 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24165020 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24165020 — Surrogate Endpoint (SUR): Blood pressure
Study 17714121 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 8749687 — Surrogate Endpoint (SUR): Blood pressure
Study 16424649 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11006039 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6337767 — Surrogate Endpoint (SUR): Blood pressure
Study 6337767 — Surrogate Endpoint (SUR): Serum potassium
Study 26143741 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22341868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17343662 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15881488 — Surrogate Endpoint (SUR): Blood pressure
Study 28750133 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28750133 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 19195263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17825150 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17825150 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17825150 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15106795 — Surrogate Endpoint (SUR): Blood pressure
Study 11252223 — Surrogate Endpoint (SUR): Blood pressure
Study 7861719 — Surrogate Endpoint (SUR): Serum creatinine
Study 412450 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23448807 — Predictive Biomarker (PRD): PSCA mRNA
Genes: PSCA; UNQ206/PRO232
Study 21368751 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 939070 — Surrogate Endpoint (SUR): Blood pressure
Study 30910592 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30910592 — Predictive Biomarker (PRD): SOX2 mRNA
Genes: SOX2
Study 30910592 — Predictive Biomarker (PRD): ALDH1A1 mRNA
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study 20430601 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 6127719 — Surrogate Endpoint (SUR): Blood pressure
Study 25896973 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25896973 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25896973 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 25896973 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study 7528271 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9177508 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 15591335 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9024169 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30545338 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 30967589 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 26803431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26803431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26803431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26803431 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 26803431 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20661086 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20661086 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 12039990 — Surrogate Endpoint (SUR): Bone mineral density
Study 31187152 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 25268043 — Surrogate Endpoint (SUR): Blood pressure
Study 21350408 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 21350408 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 24355241 — Safety Biomarker (SAF): Hyaluronic acid
Study 11004039 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 11004039 — Surrogate Endpoint (SUR): Blood pressure
Study 8625683 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27495291 — Surrogate Endpoint (SUR): Blood pressure
Study 7946856 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10739392 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29624540 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 29624540 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 31226526 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 11092646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11092646 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11092646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11092646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11092646 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 31689326 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27627098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27627098 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 28844499 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28844499 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 28844499 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21406671 — Surrogate Endpoint (SUR): Blood pressure
Study 17381964 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 31888762 — Surrogate Endpoint (SUR): Blood pressure
Study 31888762 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31888762 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24862674 — Surrogate Endpoint (SUR): Serum calcium
Study 7780288 — Surrogate Endpoint (SUR): Blood pressure
Study 344012 — Surrogate Endpoint (SUR): Blood pressure
Study 23529567 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26444095 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 26444095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15572523 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 9952095 — Surrogate Endpoint (SUR): Blood pressure
Study 7402449 — Surrogate Endpoint (SUR): Blood pressure
Study 15360029 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 11677377 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11677377 — Surrogate Endpoint (SUR): Blood pressure
Study 22669588 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 31035665 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22473458 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22473458 — Surrogate Endpoint (SUR): Blood pressure
Study 3993545 — Surrogate Endpoint (SUR): Blood pressure
Study 29946115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29946115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29946115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14688021 — Predictive Biomarker (PRD): SULT1A1 mRNA
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 9331014 — Surrogate Endpoint (SUR): Blood pressure
Study 28972039 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 28972039 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16343130 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 10467830 — Surrogate Endpoint (SUR): Serum calcium
Study 10467830 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 536969 — Surrogate Endpoint (SUR): Blood pressure
Study 24210087 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24210087 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11402974 — Surrogate Endpoint (SUR): Blood pressure
Study 9124466 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 24949820 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12482641 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11395985 — Surrogate Endpoint (SUR): Bone mineral density
Study 8383397 — Surrogate Endpoint (SUR): Serum creatinine
Study 8383397 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20825071 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20825071 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12674340 — Surrogate Endpoint (SUR): Bone mineral density
Study 25873553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25873553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21075774 — Surrogate Endpoint (SUR): Blood pressure
Study 17224434 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2405613 — Surrogate Endpoint (SUR): Blood pressure
Study 22041323 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22041323 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8857279 — Surrogate Endpoint (SUR): Blood pressure
Study 2001053 — Surrogate Endpoint (SUR): Blood pressure
Study 29382142 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23945720 — Surrogate Endpoint (SUR): Bone mineral density
Study 11302998 — Surrogate Endpoint (SUR): Blood pressure
Study 1887747 — Surrogate Endpoint (SUR): Blood pressure
Study 28199736 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28199736 — Surrogate Endpoint (SUR): Serum testosterone
Study 28199736 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22397264 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19715914 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 19715914 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19715914 — Surrogate Endpoint (SUR): Blood pressure
Study 11581559 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 11581559 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9886905 — Surrogate Endpoint (SUR): Blood pressure
Study 29688617 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 27100393 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27100393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27100393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27100393 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19455040 — Surrogate Endpoint (SUR): Blood pressure
Study 12118835 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9361169 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30115826 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30115826 — Safety Biomarker (SAF): BDNF
Study 25716546 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 22762867 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 24131872 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24131872 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30707661 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 10595868 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8706777 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26843120 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26843120 — Surrogate Endpoint (SUR): Blood pressure
Study 25259743 — Surrogate Endpoint (SUR): Blood pressure
Study 20067641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10414756 — Surrogate Endpoint (SUR): Blood pressure
Study 7594425 — Surrogate Endpoint (SUR): Blood pressure
Study 31292457 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 29977328 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 29977328 — Safety Biomarker (SAF): IL-6 and IL-10