TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10999797 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study 10999797 — Surrogate Endpoint (SUR): Blood pressure
Study 31025274 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 31025274 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24504098 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24504098 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 24504098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24504098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24504098 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12164886 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12164886 — Surrogate Endpoint (SUR): Blood pressure
Study 19920236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22830971 — Surrogate Endpoint (SUR): Blood pressure
Study 17461474 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16036039 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 12113287 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12113287 — Safety Biomarker (SAF): Reactive oxygen species
Study 16110019 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9806658 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28894768 — Safety Biomarker (SAF): Hyaluronic acid
Study 21199163 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15337703 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 15337703 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11263363 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 2850552 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29969293 — Predictive Biomarker (PRD): EPRS1 mRNA
Genes: EPRS1; EPRS; GLNS; PARS; QARS; QPRS; PIG32
Study 20216276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17711562 — Predictive Biomarker (PRD): GSTA1 mRNA
Genes: GSTA1
Study 24299553 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15975313 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12669128 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 21571362 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15497491 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15497491 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26092818 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26092818 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 26092818 — Predictive Biomarker (PRD): Hormone receptor
Study 26236130 — Surrogate Endpoint (SUR): Probing pocket depth
Study 2524203 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23593314 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12943174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9332684 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 12959279 — Surrogate Endpoint (SUR): Blood pressure
Study 24260184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8810694 — Predictive Biomarker (PRD): RAPH1 mRNA
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 22034637 — Safety Biomarker (SAF): Reactive oxygen species
Study 22034637 — Surrogate Endpoint (SUR): Serum creatinine
Study 16843455 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 16843455 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 16843455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16843455 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16843455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10427138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10427138 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 10427138 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 31810854 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 15343191 — Surrogate Endpoint (SUR): Blood pressure
Study 9301693 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 3734450 — Surrogate Endpoint (SUR): Blood pressure
Study 21122202 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21122202 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21122202 — Surrogate Endpoint (SUR): Blood pressure
Study 17452062 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8953336 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7046937 — Surrogate Endpoint (SUR): Blood pressure
Study 18050186 — Predictive Biomarker (PRD): DBF4 mRNA
Genes: DBF4; ASK; DBF4A; ZDBF1
Study 16259546 — Surrogate Endpoint (SUR): Blood pressure
Study 8035044 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29754664 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29754664 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27760869 — Surrogate Endpoint (SUR): Blood pressure
Study 22824930 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8098293 — Surrogate Endpoint (SUR): Blood pressure
Study 23300275 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20938767 — Surrogate Endpoint (SUR): Bone mineral density
Study 19245380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28604144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21052022 — Predictive Biomarker (PRD): NEDD4L mRNA
Genes: NEDD4L; KIAA0439; NEDL3
Study 8806332 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8806332 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 22802220 — Surrogate Endpoint (SUR): Blood pressure
Study 20447012 — Surrogate Endpoint (SUR): Serum uric acid
Study 17903340 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10430379 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31230397 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 29110647 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26691888 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15625142 — Surrogate Endpoint (SUR): Bone mineral density
Study 15625142 — Surrogate Endpoint (SUR): Serum calcium
Study 10207542 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26691333 — Surrogate Endpoint (SUR): Blood pressure
Study 15663548 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15663548 — Surrogate Endpoint (SUR): Serum calcium
Study 15663548 — Surrogate Endpoint (SUR): Serum creatinine
Study 7895356 — Surrogate Endpoint (SUR): Blood pressure
Study 26449252 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21328087 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21328087 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 19152130 — Surrogate Endpoint (SUR): Blood pressure
Study 2521988 — Surrogate Endpoint (SUR): Blood pressure
Study 15136961 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15136961 — Predictive Biomarker (PRD): INPP5J mRNA
Genes: INPP5J; PIB5PA; PIPP
Study 7944444 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 29307112 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25626016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25626016 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25626016 — Surrogate Endpoint (SUR): Blood pressure
Study 18387162 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 18387162 — Surrogate Endpoint (SUR): Serum calcium
Study 12682719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12682719 — Monitoring Biomarker (MOI): Procalcitonin
Study 20875371 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 14967867 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14967867 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 14967867 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22564989 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18330698 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 18330698 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28744992 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7692173 — Surrogate Endpoint (SUR): Blood pressure
Study 31724351 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 12895688 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8942562 — Surrogate Endpoint (SUR): Serum creatinine
Study 12117301 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31278521 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 31278521 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 26170027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 16652320 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1733754 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31408474 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15667798 — Surrogate Endpoint (SUR): Blood pressure
Study 21623968 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17462395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17462395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11672450 — Surrogate Endpoint (SUR): Blood pressure
Study 11672450 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23507375 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 16824730 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24245914 — Surrogate Endpoint (SUR): Blood pressure
Study 20334535 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20334535 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22577108 — Predictive Biomarker (PRD): CASR mRNA
Genes: CASR; GPRC2A; PCAR1
Study 9821232 — Surrogate Endpoint (SUR): Blood pressure
Study 9821232 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8121291 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8121291 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30999929 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30999929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30999929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24794075 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30425326 — Surrogate Endpoint (SUR): Blood pressure
Study 21666159 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11475726 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11475726 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31919501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26355382 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 23571643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31064968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31064968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28620848 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28620848 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27137715 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 23798725 — Surrogate Endpoint (SUR): Blood pressure
Study 22041444 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 19208459 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11131273 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11131273 — Surrogate Endpoint (SUR): Blood pressure
Study 3982646 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 2832549 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 25428945 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 18498885 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 18498885 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 12687595 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12687595 — Surrogate Endpoint (SUR): Blood pressure
Study 31750484 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31750484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16231260 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11249886 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26457716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19459427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14716538 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study 14716538 — Predictive Biomarker (PRD): MYL12A mRNA
Genes: MYL12A; MLCB; MRLC3; RLC
Study 2929469 — Surrogate Endpoint (SUR): Blood pressure
Study 28804807 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 25744003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25744003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23682827 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21283543 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19255328 — Surrogate Endpoint (SUR): Hematologic response
Study 16109807 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 16109807 — Surrogate Endpoint (SUR): Blood pressure
Study 395523 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 25865966 — Safety Biomarker (SAF): Reactive oxygen species
Study 16257842 — Surrogate Endpoint (SUR): Blood pressure
Study 8651966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20418299 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8748044 — Surrogate Endpoint (SUR): Blood pressure
Study 30471472 — Surrogate Endpoint (SUR): Bone mineral density
Study 26418930 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15288212 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15288212 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11404650 — Surrogate Endpoint (SUR): Bone mineral density
Study 15690237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15690237 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 963960 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30880937 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28099408 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28099408 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28099408 — Predictive Biomarker (PRD): APOA5 mRNA
Genes: APOA5; RAP3; UNQ411/PRO773
Study 28099408 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15570142 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 26224300 — Surrogate Endpoint (SUR): Blood pressure
Study 20807467 — Surrogate Endpoint (SUR): Blood pressure
Study 31666831 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 17944274 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 15081561 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27002107 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27002107 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 27002107 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27002107 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25394434 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 25394434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25394434 — Safety Biomarker (SAF): Reactive oxygen species
Study 25394434 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20412149 — Surrogate Endpoint (SUR): Blood pressure
Study 17058828 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24873996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24873996 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19684633 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 12689974 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8906513 — Surrogate Endpoint (SUR): Blood pressure
Study 8906513 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30665829 — Surrogate Endpoint (SUR): Blood pressure
Study 30544421 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 27502582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18199500 — Surrogate Endpoint (SUR): Blood pressure
Study 28692301 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 28692301 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 10626290 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 15767215 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15767215 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10223772 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10223772 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10223772 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27829181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21442803 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24637537 — Surrogate Endpoint (SUR): Serum testosterone
Study 22240264 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1860093 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29389742 — Surrogate Endpoint (SUR): Blood pressure
Study 26426999 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 2056908 — Surrogate Endpoint (SUR): Blood pressure
Study 30084414 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30084414 — Monitoring Biomarker (MOI): HBV DNA
Study 28480270 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28480270 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 28480270 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17531459 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17531459 — Surrogate Endpoint (SUR): Blood pressure
Study 17531459 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17531459 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16600640 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26277090 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3907323 — Surrogate Endpoint (SUR): Blood pressure
Study 22573119 — Surrogate Endpoint (SUR): Blood pressure
Study 18628657 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12663296 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 12663296 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 31685792 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31685792 — Surrogate Endpoint (SUR): Blood pressure
Study 31685792 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20051370 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study 20051370 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 20051370 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 18624836 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 12379291 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 10909468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10909468 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10909468 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10909468 — Safety Biomarker (SAF): IL-6 and IL-10
Study 2149514 — Surrogate Endpoint (SUR): Blood pressure
Study 7030578 — Surrogate Endpoint (SUR): Blood pressure
Study 25904073 — Surrogate Endpoint (SUR): Blood pressure
Study 15106797 — Surrogate Endpoint (SUR): Blood pressure
Study 2318222 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31550363 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP