TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28239939 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25806587 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 7927958 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7927958 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2502890 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 2502890 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 21300618 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12221048 — Surrogate Endpoint (SUR): Blood pressure
Study 6143184 — Surrogate Endpoint (SUR): Blood pressure
Study 25917895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20736449 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 20736449 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 18515817 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 18515817 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12782208 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12782208 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 12782208 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 9160584 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9160584 — Surrogate Endpoint (SUR): Blood pressure
Study 2912330 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25779951 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24113059 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 9168369 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26050790 — Predictive Biomarker (PRD): PRKRA mRNA
Genes: PRKRA; PACT; RAX; HSD-14; HSD14
Study 19351690 — Surrogate Endpoint (SUR): Blood pressure
Study 16957557 — Surrogate Endpoint (SUR): Blood pressure
Study 11110735 — Surrogate Endpoint (SUR): Blood pressure
Study 9066184 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8332009 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8332009 — Surrogate Endpoint (SUR): Blood pressure
Study 29722619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20046173 — Surrogate Endpoint (SUR): Blood pressure
Study 21613384 — Safety Biomarker (SAF): MTHFR
Study 18327092 — Surrogate Endpoint (SUR): Blood pressure
Study 22254048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22254048 — Safety Biomarker (SAF): Interleukin 1
Study 9528165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9528165 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21805462 — Surrogate Endpoint (SUR): Blood pressure
Study 9042042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9042042 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 25609939 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25609939 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16637791 — Surrogate Endpoint (SUR): Serum creatinine
Study 16637791 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8646249 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24743062 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 18158077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18158077 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18158077 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7650808 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22930789 — Predictive Biomarker (PRD): OSR1 mRNA
Genes: OSR1; ODD
Study 22930789 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 23646472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23646472 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 23646472 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23646472 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22195356 — Surrogate Endpoint (SUR): Blood pressure
Study 11598594 — Surrogate Endpoint (SUR): Bone mineral density
Study 7985599 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7985599 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7985599 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31196815 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28298543 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study 11249629 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31420735 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 20546013 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20546013 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18794647 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 18794647 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 31141968 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15451912 — Surrogate Endpoint (SUR): Blood pressure
Study 31647902 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 29196161 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 28370401 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28370401 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26510013 — Surrogate Endpoint (SUR): Blood pressure
Study 20378601 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 18803046 — Predictive Biomarker (PRD): TERF1 mRNA
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study 16533589 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 16533589 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 23111749 — Surrogate Endpoint (SUR): Blood pressure
Study 12794024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12794024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10695096 — Surrogate Endpoint (SUR): Blood pressure
Study 8934359 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31835039 — Predictive Biomarker (PRD): Activated leukocyte cell adhesionmolecule
Genes: ALCAM; MEMD
Study 31835039 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22703383 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 9458998 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20649879 — Surrogate Endpoint (SUR): Bone mineral density
Study 10933355 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10933355 — Surrogate Endpoint (SUR): Blood pressure
Study 21717778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17217712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17217712 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 17217712 — Surrogate Endpoint (SUR): Blood pressure
Study 17217712 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27262236 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10094976 — Safety Biomarker (SAF): Interleukin 12
Study 10094976 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31171016 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 20934829 — Surrogate Endpoint (SUR): Blood pressure
Study 19193505 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19193505 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19193505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3548602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25047497 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11303372 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1446996 — Surrogate Endpoint (SUR): Blood pressure
Study 2870353 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2870353 — Surrogate Endpoint (SUR): Serum testosterone
Study 30529119 — Predictive Biomarker (PRD): SPTB mRNA
Genes: SPTB; SPTB1
Study 19294693 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 19294693 — Predictive Biomarker (PRD): Phospholipase A2 inhibitory protein
Genes: ANXA1; ANX1; LPC1
Study 15470336 — Surrogate Endpoint (SUR): Blood pressure
Study 30905430 — Surrogate Endpoint (SUR): Blood pressure
Study 21415071 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11479880 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30431384 — Surrogate Endpoint (SUR): Blood pressure
Study 15715683 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 15715683 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15715683 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1345033 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 26386921 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 25563795 — Surrogate Endpoint (SUR): Blood pressure
Study 25563795 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21138533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18426991 — Surrogate Endpoint (SUR): Blood pressure
Study 30373342 — Surrogate Endpoint (SUR): Blood pressure
Study 3795978 — Surrogate Endpoint (SUR): Blood pressure
Study 3795978 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31694861 — Surrogate Endpoint (SUR): Blood pressure
Study 20713915 — Surrogate Endpoint (SUR): Blood pressure
Study 12610843 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 17075807 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 3277680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12409970 — Surrogate Endpoint (SUR): Serum creatinine
Study 7584486 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 31254640 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 31254640 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 26576593 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 26576593 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 26576593 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26576593 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19635893 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16413239 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16413239 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9364542 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8496758 — Surrogate Endpoint (SUR): Serum calcium
Study 23844613 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 21186534 — Monitoring Biomarker (MOI): HBV DNA
Study 11982739 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10432413 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10432413 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7607717 — Surrogate Endpoint (SUR): Blood pressure
Study 2215105 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 2215105 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2215105 — Surrogate Endpoint (SUR): Blood pressure
Study 10890384 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19380175 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12355477 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12355477 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8698859 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1679299 — Surrogate Endpoint (SUR): Blood pressure
Study 21540805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8062152 — Surrogate Endpoint (SUR): Bone mineral density
Study 8062152 — Surrogate Endpoint (SUR): Serum calcium
Study 8062152 — Surrogate Endpoint (SUR): Serum creatinine
Study 2543199 — Surrogate Endpoint (SUR): Blood pressure
Study 26866508 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26866508 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 31546576 — Surrogate Endpoint (SUR): Blood pressure
Study 19484669 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12499031 — Surrogate Endpoint (SUR): Blood pressure
Study 31667572 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19451281 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2892047 — Surrogate Endpoint (SUR): Bone mineral density
Study 25613431 — Predictive Biomarker (PRD): FBN1 mRNA
Genes: FBN1; FBN
Study 30666799 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30666799 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 30666799 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9591742 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 29768465 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 22640986 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11527144 — Surrogate Endpoint (SUR): Blood pressure
Study 12944569 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26199198 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 9550542 — Surrogate Endpoint (SUR): Serum uric acid
Study 24009749 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 21720594 — Surrogate Endpoint (SUR): Bone mineral density
Study 11748361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8222513 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29557487 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 25649051 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 22654433 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11986110 — Surrogate Endpoint (SUR): Blood pressure
Study 9607375 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9607375 — Surrogate Endpoint (SUR): Blood pressure
Study 7612039 — Surrogate Endpoint (SUR): Bone mineral density
Study 6383749 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 6383749 — Surrogate Endpoint (SUR): Serum creatinine
Study 27310330 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19961902 — Safety Biomarker (SAF): DRD2
Study 12856809 — Surrogate Endpoint (SUR): Bone mineral density
Study 7851278 — Surrogate Endpoint (SUR): Blood pressure
Study 28366730 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23765945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27423921 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 8613276 — Surrogate Endpoint (SUR): Blood pressure
Study 9745451 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 2831524 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29580733 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29580733 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29580733 — Predictive Biomarker (PRD): Hormone receptor
Study 23090678 — Surrogate Endpoint (SUR): Bone mineral density
Study 27142448 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24522178 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21313892 — Surrogate Endpoint (SUR): Blood pressure
Study 17468586 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11823923 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 9817530 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2674395 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31259755 — Surrogate Endpoint (SUR): Blood pressure
Study 31106377 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 31106377 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 26135349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11815428 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11815428 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11815428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11815428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21279975 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17551418 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27615555 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 21501481 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16822585 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16822585 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 11123197 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9429014 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24087989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24087989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19381991 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19381991 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11327443 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21619382 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21619382 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21619382 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21619382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16797249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8416666 — Surrogate Endpoint (SUR): Blood pressure
Study 20862711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20862711 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 20862711 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 11903959 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9815869 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31820121 — Surrogate Endpoint (SUR): Bone mineral density
Study 30365821 — Surrogate Endpoint (SUR): Blood pressure
Study 22155532 — Surrogate Endpoint (SUR): Bone mineral density
Study 1959365 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25661189 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25661189 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 20605696 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20605696 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20605696 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 20605696 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19563059 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 15453552 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 15453552 — Surrogate Endpoint (SUR): Blood pressure
Study 11816915 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9802141 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7543352 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28429365 — Surrogate Endpoint (SUR): Bacterial count
Study 26027630 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6086181 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30304715 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study 17468062 — Surrogate Endpoint (SUR): Bone mineral density
Study 15131770 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15131770 — Surrogate Endpoint (SUR): Blood pressure
Study 15131770 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31361922 — Surrogate Endpoint (SUR): Bone mineral density
Study 25644342 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15356432 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 14627176 — Surrogate Endpoint (SUR): Blood pressure
Study 29898838 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 22764184 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 19013239 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON