TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22672501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22672501 — Safety Biomarker (SAF): Interleukin 1
Study 3327931 — Surrogate Endpoint (SUR): Blood pressure
Study 3327931 — Surrogate Endpoint (SUR): Serum potassium
Study 31389672 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 25680623 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24156558 — Surrogate Endpoint (SUR): Blood pressure
Study 16918261 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 28453759 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study 28453759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28453759 — Predictive Biomarker (PRD): CCL25 mRNA
Genes: CCL25; SCYA25; TECK
Study 28453759 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 26222774 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 12090818 — Surrogate Endpoint (SUR): Blood pressure
Study 1951147 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 29061621 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 29061621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25392341 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24811963 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 11222112 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 9603683 — Surrogate Endpoint (SUR): Blood pressure
Study 30943497 — Surrogate Endpoint (SUR): Blood pressure
Study 29208690 — Surrogate Endpoint (SUR): Blood pressure
Study 23141486 — Surrogate Endpoint (SUR): Blood pressure
Study 23141486 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18713842 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25455421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25455421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23292038 — Safety Biomarker (SAF): Hyaluronic acid
Study 15592329 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11359439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11359439 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 11359439 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 7937908 — Predictive Biomarker (PRD): Microsatellite instability
Study 3218660 — Surrogate Endpoint (SUR): Blood pressure
Study 3218660 — Surrogate Endpoint (SUR): Serum calcium
Study 21346512 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10894321 — Surrogate Endpoint (SUR): Blood pressure
Study 7402771 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30481106 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9918518 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17186304 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8219679 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8219679 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 27180890 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 27180890 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23394782 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 31174586 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study 27085996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15957834 — Surrogate Endpoint (SUR): Serum creatinine
Study 12060619 — Predictive Biomarker (PRD): PSCA mRNA
Genes: PSCA; UNQ206/PRO232
Study 7703389 — Surrogate Endpoint (SUR): Blood pressure
Study 30843481 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20178563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20178563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20178563 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10431992 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21088253 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18440147 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 18440147 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 10846036 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2878747 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 25778646 — Predictive Biomarker (PRD): FAS mRNA
Genes: FAS; APT1; FAS1; TNFRSF6
Study 19469405 — Surrogate Endpoint (SUR): Blood pressure
Study 11961630 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10404953 — Surrogate Endpoint (SUR): Blood pressure
Study 23933474 — Predictive Biomarker (PRD): UCN3 mRNA
Genes: UCN3; SPC
Study 18362418 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18362418 — Surrogate Endpoint (SUR): Blood pressure
Study 16485520 — Surrogate Endpoint (SUR): Blood pressure
Study 12095184 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8154311 — Surrogate Endpoint (SUR): Bone mineral density
Study 31462727 — Surrogate Endpoint (SUR): Blood pressure
Study 31462727 — Surrogate Endpoint (SUR): Serum uric acid
Study 18179556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18179556 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 18179556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18179556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16598749 — Predictive Biomarker (PRD): Hormone receptor
Study 2439814 — Surrogate Endpoint (SUR): Blood pressure
Study 27773406 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 20427668 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 20427668 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16162204 — Surrogate Endpoint (SUR): Serum creatinine
Study 23370835 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21610516 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 26585569 — Predictive Biomarker (PRD): MAG mRNA
Genes: MAG; GMA
Study 26865338 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 14624169 — Surrogate Endpoint (SUR): Blood pressure
Study 17660031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15957832 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15957832 — Surrogate Endpoint (SUR): Blood pressure
Study 2209678 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7470854 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 2688586 — Surrogate Endpoint (SUR): Blood pressure
Study 1081271 — Surrogate Endpoint (SUR): Bone mineral density
Study 7700070 — Surrogate Endpoint (SUR): Blood pressure
Study 19731193 — Surrogate Endpoint (SUR): Blood pressure
Study 16548349 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 12963608 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 31210529 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27436584 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 27436584 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 22172468 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 12692805 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 10871712 — Surrogate Endpoint (SUR): Blood pressure
Study 24970858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10965418 — Surrogate Endpoint (SUR): Blood pressure
Study 20640584 — Safety Biomarker (SAF): Hyaluronic acid
Study 7494588 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23461723 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 16682542 — Surrogate Endpoint (SUR): Serum testosterone
Study 11369986 — Surrogate Endpoint (SUR): Blood pressure
Study 9160527 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18252894 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 9003110 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27274999 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27256731 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27256731 — Safety Biomarker (SAF): BDNF
Study 23017356 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23017356 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23017356 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 26263223 — Predictive Biomarker (PRD): GNPDA2 mRNA
Genes: GNPDA2; GNP2
Study 26263223 — Surrogate Endpoint (SUR): Blood pressure
Study 17473202 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 17473202 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15185770 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 15185770 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9822092 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2572566 — Surrogate Endpoint (SUR): Blood pressure
Study 18329197 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 24755130 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24755130 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 17227801 — Surrogate Endpoint (SUR): Bone mineral density
Study 30283911 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16604131 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9424322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9424322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28762106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22283559 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 14564591 — Surrogate Endpoint (SUR): Serum creatinine
Study 1705140 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 25936324 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25936324 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21946197 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3605735 — Surrogate Endpoint (SUR): Blood pressure
Study 25645987 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 24171516 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 19766757 — Surrogate Endpoint (SUR): Serum creatinine
Study 14995938 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11746538 — Surrogate Endpoint (SUR): Blood pressure
Study 9541692 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 30810619 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21550429 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 21550429 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 21550429 — Predictive Biomarker (PRD): E2F1 mRNA
Genes: E2F1; RBBP3
Study 12686335 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7606629 — Surrogate Endpoint (SUR): Blood pressure
Study 28762606 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18004611 — Surrogate Endpoint (SUR): Bone mineral density
Study 14555563 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25922062 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27045034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24578135 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22925537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22925537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22925537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27801706 — Surrogate Endpoint (SUR): Bone mineral density
Study 9211578 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 28892591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28892591 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 18034777 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11074199 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 27401892 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27216240 — Surrogate Endpoint (SUR): Serum creatinine
Study 24713285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1113235 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 30958045 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30958045 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20940336 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 20940336 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 8030656 — Surrogate Endpoint (SUR): Blood pressure
Study 18653268 — Surrogate Endpoint (SUR): Blood pressure
Study 30709958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28682289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 11528252 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 11528252 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 7836521 — Surrogate Endpoint (SUR): Sperm parameters
Study 19422759 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 15385013 — Surrogate Endpoint (SUR): Blood pressure
Study 11527684 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 27464544 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27464544 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 20393026 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 15991060 — Surrogate Endpoint (SUR): Blood pressure
Study 31595861 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 25835116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25835116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25835116 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25835116 — Safety Biomarker (SAF): IL-6 and IL-10
Study 31608503 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 28710229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26338453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15851238 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11437040 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 7526007 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1157005 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 23953528 — Surrogate Endpoint (SUR): Serum creatinine
Study 21741088 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21741088 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28644774 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 17063425 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 6412795 — Surrogate Endpoint (SUR): Blood pressure
Study 21252018 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 18214425 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 8869676 — Surrogate Endpoint (SUR): Blood pressure
Study 30217233 — Surrogate Endpoint (SUR): Blood pressure
Study 25196301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12011970 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10466952 — Predictive Biomarker (PRD): PIMREG mRNA
Genes: PIMREG; CATS; FAM64A; RCS1
Study 31787562 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27918780 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15006828 — Surrogate Endpoint (SUR): Blood pressure
Study 9033316 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24132138 — Surrogate Endpoint (SUR): Blood pressure
Study 6092555 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 29920211 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 29920211 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 29920211 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24401211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24401211 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11811169 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 21932114 — Surrogate Endpoint (SUR): Bone mineral density
Study 21932114 — Surrogate Endpoint (SUR): Serum calcium
Study 19188545 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18265541 — Surrogate Endpoint (SUR): Blood pressure
Study 18265541 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18265541 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9164824 — Surrogate Endpoint (SUR): Blood pressure
Study 31200662 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 31200662 — Surrogate Endpoint (SUR): Blood pressure
Study 25880814 — Surrogate Endpoint (SUR): Pathological complete response
Study 19001742 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30019357 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 11527172 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 11527172 — Safety Biomarker (SAF): Hyaluronic acid
Study 7920930 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29407633 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 29407633 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18842969 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18842969 — Surrogate Endpoint (SUR): Blood pressure
Study 2787887 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 23760911 — Surrogate Endpoint (SUR): Blood pressure
Study 18714500 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 27062408 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29684092 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25578377 — Surrogate Endpoint (SUR): Pathological complete response
Study 28829670 — Surrogate Endpoint (SUR): Bone mineral density
Study 27225761 — Predictive Biomarker (PRD): NE
Study 23864720 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11211168 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9772136 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 9772136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30281924 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30281924 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 30281924 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 30281924 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 30281924 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 30281924 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 16452736 — Surrogate Endpoint (SUR): Bone mineral density
Study 15212653 — Surrogate Endpoint (SUR): Blood pressure
Study 15212653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15212653 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 15212653 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11301961 — Surrogate Endpoint (SUR): Blood pressure
Study 19745828 — Surrogate Endpoint (SUR): Blood pressure
Study 15891523 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15891523 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 15891523 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15891523 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11641293 — Surrogate Endpoint (SUR): Blood pressure
Study 30051179 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 30051179 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 30051179 — Predictive Biomarker (PRD): Activated leukocyte cell adhesionmolecule
Genes: ALCAM; MEMD
Study 30051179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28676236 — Surrogate Endpoint (SUR): Blood pressure
Study 26041510 — Predictive Biomarker (PRD): CS mRNA
Genes: CS