TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04025424 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00304226 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02593435 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02593435 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03420716 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02833766 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00797329 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00647868 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00195689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04922749 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01195272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01195272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02310243 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT04249024 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00336908 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study NCT02629770 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study NCT02159781 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT02742350 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02527018 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02575976 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05050890 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02613741 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02613741 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03822507 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT03464123 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01649271 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02771795 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03147339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03309007 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT01963130 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02473783 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT00037635 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT04539418 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT00450619 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00450619 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00450619 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT03018808 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00139425 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04238715 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT02657330 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study NCT02569736 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02483143 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02654678 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04941339 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01177059 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00050232 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT01876394 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01196780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03529136 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02338622 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02338622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02338622 — Predictive Biomarker (PRD): AKT1S1 mRNA
Genes: AKT1S1; PRAS40
Study NCT02680431 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT02680431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT02188550 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02093117 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02963441 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03217396 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT01270737 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03484117 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02950870 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04407494 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03738020 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01138865 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00701948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00229736 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study NCT00364221 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02890836 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00430495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01955811 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT01547949 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT02053623 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03516214 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02053480 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT00704730 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00704730 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00704730 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT03810443 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01946360 — Surrogate Endpoint (SUR): Serum potassium
Study NCT01946360 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00045175 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study NCT02086136 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01988506 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03533127 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01532479 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04001101 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT01067391 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03976115 — Predictive Biomarker (PRD): DDO mRNA
Genes: DDO
Study NCT03075111 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT03075111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00622466 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01246401 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00667810 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04209205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00712426 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT02637375 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02824718 — Predictive Biomarker (PRD): CASR mRNA
Genes: CASR; GPRC2A; PCAR1
Study NCT00153608 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT00153608 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02650817 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01120262 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT04131543 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT02253030 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02058212 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03287973 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01389583 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01389583 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT02192749 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02929446 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03409744 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02460510 — Surrogate Endpoint (SUR): Serum sodium
Study NCT02792959 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT01711320 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT04712617 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study NCT04712617 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study NCT02075671 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT03528421 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03528421 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT04614506 — Predictive Biomarker (PRD): SCN1A mRNA
Genes: SCN1A; NAC1; SCN1
Study NCT00336765 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00336765 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT04708639 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04708639 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT05514652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03351803 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03811496 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT03811496 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT03811496 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT00604136 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04467268 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03440255 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT04342182 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03867461 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03324932 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00968292 — Predictive Biomarker (PRD): KCNN3 mRNA
Genes: KCNN3; K3
Study NCT00587015 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT02044796 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04482699 — Safety Biomarker (SAF): Th2 cell
Study NCT01541306 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT00003138 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02177136 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT03357757 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT01204450 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00001345 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT01157780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01157780 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT02658539 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00822848 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT02431429 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT06458842 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00967044 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00967044 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT00967044 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study NCT01718548 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT01220934 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03195153 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00215761 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02920918 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00977730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03898518 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04766736 — Safety Biomarker (SAF): Netrin-1
Genes: NTN1; NTN1L
Study NCT01046266 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01046266 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03547336 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01836406 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06713785 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04567030 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00061243 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01251029 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT01251029 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT03728634 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT00026221 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02914327 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04120818 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01533064 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study NCT03501745 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01443936 — Predictive Biomarker (PRD): VTN mRNA
Genes: VTN
Study NCT03816410 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT02611674 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02611674 — Predictive Biomarker (PRD): DBNL mRNA
Genes: DBNL; CMAP; SH3P7; PP5423
Study NCT03120533 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00516009 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT00267943 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03982472 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03880916 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT04102852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00672165 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT03332927 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03332927 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03332927 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04514965 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT04514965 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT01206764 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01206764 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01206764 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT04314232 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00496561 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT02926820 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT02506920 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT05623943 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT01305395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study NCT04943978 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02691793 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT02691793 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT01951716 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03712501 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03712501 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00336076 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT04093856 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00975650 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00437879 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01025479 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00840047 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02618590 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03048253 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03116893 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study NCT04561193 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02357329 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04423393 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00386061 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03514641 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04327713 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT02570113 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04287348 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00505375 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03907384 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01632111 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03093727 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT00057993 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01159197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00158600 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT01483053 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02862496 — Surrogate Endpoint (SUR): Serum calcium
Study NCT00264368 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02584400 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00716079 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00105976 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT02398773 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT03879330 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01369433 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04276129 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT01970930 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01935362 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00822471 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03500653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03500653 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study NCT00603434 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00603434 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01939496 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00006022 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03076463 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05301530 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03832881 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study NCT02963311 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02536326 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03061682 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01829841 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01829841 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01829841 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study NCT04375683 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04356066 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT03078036 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03078036 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03078036 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03290365 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03058419 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03058419 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT03058419 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT03058419 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT03058419 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT03058419 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19