TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27188262 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 27189066 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27190101 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27190101 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 27195659 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 27196139 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27196139 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27197299 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 27199429 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27199429 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27199889 — Predictive Biomarker (PRD): LGSN mRNA
Genes: LGSN; GLULD1; LGS
Study 27206943 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27206943 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27206943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27207512 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 27207512 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 27207532 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 27207972 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 27207972 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27207972 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27209012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27209254 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27209293 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 27211104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27211104 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27211104 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 27211104 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27212246 — Predictive Biomarker (PRD): HMBS mRNA
Genes: HMBS; PBGD; UPS
Study 27212697 — Surrogate Endpoint (SUR): Bone mineral density
Study 27212697 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27213625 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 27214046 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 27214046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27214241 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 27216309 — Surrogate Endpoint (SUR): Blood pressure
Study 27217450 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27219621 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27222654 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27224553 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 27227701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27230813 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 27232186 — Surrogate Endpoint (SUR): Blood pressure
Study 27232579 — Predictive Biomarker (PRD): LOXL2 mRNA
Genes: LOXL2
Study 27232917 — Surrogate Endpoint (SUR): Blood pressure
Study 27232917 — Surrogate Endpoint (SUR): Serum uric acid
Study 27233802 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 27233802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 27233802 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 27234335 — Surrogate Endpoint (SUR): Blood pressure
Study 27235137 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 27235137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27235137 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 27235137 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 27235137 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study 27236390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27242521 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 27244882 — Surrogate Endpoint (SUR): Pathological complete response
Study 27245312 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 27245312 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study 27245663 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 27246604 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 27246604 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27246911 — Surrogate Endpoint (SUR): Blood pressure
Study 27249553 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27251684 — Surrogate Endpoint (SUR): Blood pressure
Study 27251684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27253664 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 27253664 — Predictive Biomarker (PRD): CUL1 mRNA
Genes: CUL1
Study 27255499 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 27255499 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 27255499 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27255499 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 27255499 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 27255678 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 27257978 — Monitoring Biomarker (MOI): HBV DNA
Study 27258098 — Surrogate Endpoint (SUR): Blood pressure
Study 27258647 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27260636 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 27260636 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 27261237 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27262736 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27262736 — Surrogate Endpoint (SUR): Serum creatinine
Study 27266507 — Surrogate Endpoint (SUR): Blood pressure
Study 27266702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27266721 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 27267549 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27267549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27267942 — Surrogate Endpoint (SUR): Blood pressure
Study 27268271 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27269295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27269940 — Predictive Biomarker (PRD): RTL1 mRNA
Genes: RTL1; MAR1; MART1; PEG11
Study 27269940 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study 27270177 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 27270177 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 27270475 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 27271157 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 27276561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 27276561 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 27281556 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27281556 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27281556 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27281556 — Predictive Biomarker (PRD): Hormone receptor
Study 27281773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27281773 — Surrogate Endpoint (SUR): Blood pressure
Study 27281793 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 27282141 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27282141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27282141 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 27282141 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27282998 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 27282998 — Predictive Biomarker (PRD): FCGR2A mRNA
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 27285281 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 27285295 — Surrogate Endpoint (SUR): Blood pressure
Study 27285295 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27285295 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27286790 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 27287231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27287512 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27289552 — Surrogate Endpoint (SUR): Pathological complete response
Study 27294305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27294768 — Surrogate Endpoint (SUR): Blood pressure
Study 27296315 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 27296315 — Safety Biomarker (SAF): Cytochrome c
Study 27296397 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27296397 — Surrogate Endpoint (SUR): Blood pressure
Study 27296397 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27297790 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27300170 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 27300170 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27300475 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 27300572 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 27300572 — Surrogate Endpoint (SUR): Blood pressure
Study 27300572 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27300572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27302659 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27307294 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 27307294 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 27307294 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 27309906 — Predictive Biomarker (PRD): RARS1 mRNA
Genes: RARS1; RARS
Study 27312051 — Predictive Biomarker (PRD): SPAG5 mRNA
Genes: SPAG5
Study 27312804 — Surrogate Endpoint (SUR): Blood pressure
Study 27313852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27314177 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 27316444 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 27317257 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 27318133 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study 27319305 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27325334 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 27325334 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27325334 — Predictive Biomarker (PRD): XIST
Study 27325685 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27325685 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 27325856 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 27325856 — Predictive Biomarker (PRD): Microsatellite instability
Study 27328699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27329247 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27329247 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27329447 — Surrogate Endpoint (SUR): Blood pressure
Study 27330001 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27330024 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 27330808 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 27330808 — Predictive Biomarker (PRD): MAGEA3 mRNA
Genes: MAGEA3; MAGE3
Study 27330808 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27333947 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 27334557 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27334671 — Surrogate Endpoint (SUR): Blood pressure
Study 27335060 — Surrogate Endpoint (SUR): Serum creatinine
Study 27336786 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27336786 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 27336786 — Predictive Biomarker (PRD): CXCR5 mRNA
Genes: CXCR5; BLR1; MDR15
Study 27338143 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 27338143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27338191 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 27340749 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 27342580 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 27342748 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27347680 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 27347680 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 27347680 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27347680 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 27350064 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study 27350064 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27352953 — Surrogate Endpoint (SUR): Blood pressure
Study 27354021 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 27354274 — Surrogate Endpoint (SUR): Blood pressure
Study 27354477 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27354477 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 27354481 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27355533 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 27355865 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 27355865 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27356482 — Surrogate Endpoint (SUR): Blood pressure
Study 27357090 — Surrogate Endpoint (SUR): Blood pressure
Study 27357108 — Predictive Biomarker (PRD): Microsatellite instability
Study 27357468 — Monitoring Biomarker (MOI): Procalcitonin
Study 27357468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27357840 — Surrogate Endpoint (SUR): Blood pressure
Study 27358078 — Surrogate Endpoint (SUR): Blood pressure
Study 27358088 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 27358088 — Surrogate Endpoint (SUR): Blood pressure
Study 27358490 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 27369488 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 27371698 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 27371698 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 27371698 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 27374464 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 27374464 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 27375040 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 27376543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27378554 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 27378554 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 27381904 — Surrogate Endpoint (SUR): Hematologic response
Study 27382096 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27384242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27384242 — Monitoring Biomarker (MOI): Procalcitonin
Study 27384242 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27388672 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 27389402 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 27389402 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 27389402 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 27390845 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27390845 — Predictive Biomarker (PRD): Hormone receptor
Study 27392483 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 27396777 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 27398025 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 27398025 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27400222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27400814 — Surrogate Endpoint (SUR): Blood pressure
Study 27400896 — Predictive Biomarker (PRD): LMNA mRNA
Genes: LMNA; LMN1
Study 27400896 — Surrogate Endpoint (SUR): Bone mineral density
Study 27400898 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27402060 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27402391 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27402854 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27402890 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 27403291 — Predictive Biomarker (PRD): PEPD mRNA
Genes: PEPD; PRD
Study 27403334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27403996 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 27403996 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 27404941 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 27404941 — Predictive Biomarker (PRD): T-cell surface glycoprotein CD3 epsilon
Genes: CD3E; T3E
Study 27405442 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27405963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27405963 — Surrogate Endpoint (SUR): Blood pressure
Study 27406645 — Surrogate Endpoint (SUR): Blood pressure
Study 27408945 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27408945 — Surrogate Endpoint (SUR): Blood pressure
Study 27411053 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 27411053 — Predictive Biomarker (PRD): UBC mRNA
Genes: UBC
Study 27411053 — Predictive Biomarker (PRD): RPL30 mRNA
Genes: RPL30
Study 27411053 — Predictive Biomarker (PRD): RPL37A mRNA
Genes: RPL37A
Study 27411053 — Predictive Biomarker (PRD): RPLP0 mRNA
Genes: RPLP0
Study 27411053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27411053 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 27411053 — Predictive Biomarker (PRD): OAZ1 mRNA
Genes: OAZ1; OAZ
Study 27411053 — Predictive Biomarker (PRD): DUSP1 mRNA
Genes: DUSP1; CL100; MKP1; PTPN10; VH1
Study 27411053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Protein S100-P
Genes: S100P; S100E
Study 27411452 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27411452 — Surrogate Endpoint (SUR): Blood pressure
Study 27411683 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 27412114 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27412386 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 27412526 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 27412889 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 27413040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27413040 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27414521 — Predictive Biomarker (PRD): TNXB mRNA
Genes: TNXB; HXBL; TNX; TNXB1; TNXB2; XB
Study 27415006 — Surrogate Endpoint (SUR): Serum creatinine
Study 27418050 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27418632 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27418646 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 27418929 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27421618 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27423106 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 27423106 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein