TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03950778 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02538276 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03264443 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00126646 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT02324010 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03963336 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01672879 — Predictive Biomarker (PRD): LOXL2 mRNA
Genes: LOXL2
Study NCT03926442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03926442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03926442 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT03051165 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03631953 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00675831 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00675831 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02092116 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01309789 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT04643847 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04643847 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00825695 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03150147 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT03150147 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study NCT00422643 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00137995 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03423433 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03279861 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00546754 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05600335 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT00005363 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01833923 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01833923 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study NCT03943290 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03571360 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01839526 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02698813 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00807937 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01823380 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02235792 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study NCT01840488 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT01619293 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT02502708 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT04380467 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03427307 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT03608995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02540408 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02540408 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03204565 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01402479 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04345510 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02036307 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03097770 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00109642 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02789085 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study NCT02001818 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02001818 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01767714 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01767714 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03837990 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT00860626 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00613782 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00613782 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03262935 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00141349 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01634893 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01634893 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01634893 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT03336086 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study NCT01960244 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT03109795 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02811120 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study NCT02054039 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT01831245 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT01708798 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00572104 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01266330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01266330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01001936 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study NCT00152945 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02084849 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT02191319 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04554732 — Predictive Biomarker (PRD): FGF7 mRNA
Genes: FGF7; KGF
Study NCT01610297 — Predictive Biomarker (PRD): Liver iron
Study NCT02639910 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00204113 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT03278587 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03549338 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03549338 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04593251 — Predictive Biomarker (PRD): CALY mRNA
Genes: CALY; DRD1IP
Study NCT01020045 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT01765231 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02191098 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study NCT00921115 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02290613 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03433586 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02270658 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03599518 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03884153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00951704 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00422006 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04404166 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00068601 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00068601 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00532129 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01625234 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03761472 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02948764 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT03372473 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT05798273 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02035670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03373708 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03373708 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03373708 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT02880111 — Predictive Biomarker (PRD): DMBT1 mRNA
Genes: DMBT1; GP340
Study NCT03069313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04244240 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01340222 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT01340222 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT01340222 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01340222 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT00876863 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04113798 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04113798 — Safety Biomarker (SAF): BDNF
Study NCT00957242 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02701036 — Predictive Biomarker (PRD): ZFYVE9 mRNA
Genes: ZFYVE9; MADHIP; SARA; SMADIP
Study NCT01519037 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00847834 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00737724 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02348957 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02348957 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00338572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00338572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00338572 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00338572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00338572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT03527160 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03527160 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03909412 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01583114 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03197610 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT00040313 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03133234 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03133234 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03827369 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04297371 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04544254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00358033 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03584347 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01599104 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06224946 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06224946 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03050814 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02438904 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01239758 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01239758 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04364139 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01294215 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01005641 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01005641 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01933802 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01331681 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04282824 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02439905 — Safety Biomarker (SAF): Interleukin 1
Study NCT02439905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03525002 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study NCT01388725 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT01388725 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01388725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01388725 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03917303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02015520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03302403 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03302403 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03302403 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT05082636 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT05082636 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04218890 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT04218890 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study NCT04218890 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT04079400 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT00039000 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01106157 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT03230318 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT01234181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01234181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04296227 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02706717 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03058198 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03058198 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00226538 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02413944 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT04575740 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02284022 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT00869011 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00117936 — Safety Biomarker (SAF): Fibroblast growth factor 1
Genes: FGF1
Study NCT01137617 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT03107546 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04169698 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04353934 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01490918 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00898170 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06160141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06160141 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06160141 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01816022 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04456322 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01501604 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT01501604 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00595413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01390818 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study NCT02034968 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00808106 — Predictive Biomarker (PRD): GPR143 mRNA
Genes: GPR143; OA1
Study NCT02852798 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00431704 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03072043 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01130246 — Predictive Biomarker (PRD): VSIR mRNA
Genes: VSIR; C10orf54; SISP1; VISTA; PP2135; UNQ730/PRO1412
Study NCT01362153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01943786 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01943786 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01943786 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01943786 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02342353 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03635632 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05723744 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00004104 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01514344 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04110223 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study NCT02806934 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00462358 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04390269 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT03066115 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00738023 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00738023 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04115683 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04115683 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04115683 — Safety Biomarker (SAF): BDNF
Study NCT04115683 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02442505 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01215344 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study NCT01112033 — Predictive Biomarker (PRD): BLVRA mRNA
Genes: BLVRA; BLVR; BVR
Study NCT04484935 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT02178098 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00826657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02709850 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study NCT00893178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00003612 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03169894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02903199 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT04005482 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04537403 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT02444858 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01951196 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03399669 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00967434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1