TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10656954 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 10656954 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10656954 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19846181 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 8137272 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 7014104 — Surrogate Endpoint (SUR): Blood pressure
Study 18842788 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10487375 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 10487375 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10487375 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16142748 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study 16142748 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 16142748 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10363725 — Predictive Biomarker (PRD): MINK1 mRNA
Genes: MINK1; B55; MAP4K6; MINK; YSK2; ZC3
Study 10363725 — Predictive Biomarker (PRD): TNFRSF25 mRNA
Genes: TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; UNQ455/PRO779
Study 10363725 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 2028004 — Surrogate Endpoint (SUR): Serum creatinine
Study 31014702 — Predictive Biomarker (PRD): ETV5 mRNA
Genes: ETV5; ERM
Study 28415943 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23574969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23574969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9165176 — Surrogate Endpoint (SUR): Blood pressure
Study 31760132 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8664034 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 6847424 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 19056555 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 11586485 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 913863 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26083701 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 29578578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18360782 — Surrogate Endpoint (SUR): Blood pressure
Study 10051701 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 26365444 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 8430713 — Surrogate Endpoint (SUR): Blood pressure
Study 25006070 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 20552353 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 2884853 — Surrogate Endpoint (SUR): Blood pressure
Study 21617527 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21617527 — Safety Biomarker (SAF): BDNF
Study 18158312 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 14521738 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9407509 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9407509 — Surrogate Endpoint (SUR): Blood pressure
Study 1362778 — Safety Biomarker (SAF): Hyaluronic acid
Study 1362778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2862808 — Surrogate Endpoint (SUR): Serum potassium
Study 27497716 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 22045413 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17651149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17651149 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 29943271 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29943271 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 29943271 — Surrogate Endpoint (SUR): Blood pressure
Study 28740376 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20955266 — Surrogate Endpoint (SUR): Serum testosterone
Study 17240287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2112634 — Surrogate Endpoint (SUR): Serum triglycerides
Study 496555 — Surrogate Endpoint (SUR): Serum calcium
Study 28698947 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 21882343 — Predictive Biomarker (PRD): PDCD4 mRNA
Genes: PDCD4; H731
Study 21882343 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21882343 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 16113431 — Surrogate Endpoint (SUR): Bone mineral density
Study 9734729 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31722404 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31722404 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 31722404 — Safety Biomarker (SAF): BDNF
Study 28843241 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 28843241 — Surrogate Endpoint (SUR): Serum calcium
Study 28843241 — Surrogate Endpoint (SUR): Bone mineral density
Study 25791025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25791025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25791025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23795788 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 23795788 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19001519 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 10904459 — Surrogate Endpoint (SUR): Bone mineral density
Study 22829267 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 18206738 — Surrogate Endpoint (SUR): Serum creatinine
Study 26786921 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 22040870 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 22040870 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 22040870 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 22040870 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19169239 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11345366 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11345366 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16125523 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12123399 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12123399 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12123399 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17317857 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 17317857 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 15159317 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 3895761 — Surrogate Endpoint (SUR): Blood pressure
Study 30679315 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24659622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 24659622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24659622 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 10200837 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 314759 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8980871 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 16790651 — Surrogate Endpoint (SUR): Blood pressure
Study 22799766 — Surrogate Endpoint (SUR): Blood pressure
Study 26308174 — Surrogate Endpoint (SUR): Blood pressure
Study 24050855 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19142758 — Surrogate Endpoint (SUR): Blood pressure
Study 648737 — Surrogate Endpoint (SUR): Blood pressure
Study 21203888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9493258 — Surrogate Endpoint (SUR): Blood pressure
Study 28952798 — Surrogate Endpoint (SUR): Blood pressure
Study 16423119 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25423960 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 11755562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29962032 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29962032 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 11208687 — Surrogate Endpoint (SUR): Blood pressure
Study 24528179 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study 17123473 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 25992914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19458107 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 19458107 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11403509 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11403509 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18006539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18006539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10700598 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 31282129 — Surrogate Endpoint (SUR): Serum creatinine
Study 30100904 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 30100904 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 26879651 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 17598895 — Surrogate Endpoint (SUR): Blood pressure
Study 21491012 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 12072872 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10321438 — Surrogate Endpoint (SUR): Blood pressure
Study 29986745 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 27778191 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 17343981 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10021954 — Surrogate Endpoint (SUR): Blood pressure
Study 27613946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9649160 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 24835760 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 24835760 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20530281 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 28267900 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 15170918 — Surrogate Endpoint (SUR): Bone mineral density
Study 9663183 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27565841 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 1950542 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 23537492 — Surrogate Endpoint (SUR): Blood pressure
Study 11177202 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9296413 — Surrogate Endpoint (SUR): Blood pressure
Study 8400098 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8400098 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22423894 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 18687165 — Surrogate Endpoint (SUR): Blood pressure
Study 8638794 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1762385 — Surrogate Endpoint (SUR): Serum potassium
Study 30893392 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 28099220 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 28099220 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28099220 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15066665 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15066665 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15066665 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15066665 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 10448637 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28720121 — Surrogate Endpoint (SUR): Blood pressure
Study 21422479 — Surrogate Endpoint (SUR): Bone mineral density
Study 19221011 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 18218205 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15166004 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7993937 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11339688 — Surrogate Endpoint (SUR): Blood pressure
Study 3370065 — Surrogate Endpoint (SUR): Blood pressure
Study 26847813 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 21093231 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18333861 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 18333861 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 18333861 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22765352 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18812416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12891162 — Surrogate Endpoint (SUR): Blood pressure
Study 10481520 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8570130 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 31618129 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 6813444 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 19925199 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 15470338 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1390328 — Surrogate Endpoint (SUR): Blood pressure
Study 31820600 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30322824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27086089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17604332 — Surrogate Endpoint (SUR): Blood pressure
Study 12373063 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2106402 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28784120 — Surrogate Endpoint (SUR): Blood pressure
Study 8333807 — Surrogate Endpoint (SUR): Blood pressure
Study 29540327 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29540327 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27054529 — Surrogate Endpoint (SUR): Blood pressure
Study 18302679 — Surrogate Endpoint (SUR): Bacterial count
Study 12846762 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8872633 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 6858932 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20452781 — Safety Biomarker (SAF): Reactive oxygen species
Study 9124832 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9124832 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9124832 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9124832 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 1559542 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26796076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24901809 — Surrogate Endpoint (SUR): Blood pressure
Study 20938438 — Surrogate Endpoint (SUR): Blood pressure
Study 16142862 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 16142862 — Surrogate Endpoint (SUR): Blood pressure
Study 9426847 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9426847 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9426847 — Surrogate Endpoint (SUR): Blood pressure
Study 12098612 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 7780131 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7780131 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7780131 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22545190 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 15981555 — Surrogate Endpoint (SUR): Blood pressure
Study 10606909 — Predictive Biomarker (PRD): ALPK1 mRNA
Genes: ALPK1; KIAA1527; LAK
Study 10606909 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8847783 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 29427823 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29427823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29427823 — Surrogate Endpoint (SUR): Serum calcium
Study 11263112 — Surrogate Endpoint (SUR): Bone mineral density
Study 8107484 — Surrogate Endpoint (SUR): Blood pressure
Study 17509197 — Predictive Biomarker (PRD): TSPY1 mRNA
Genes: TSPY1; TSPY
Study 25656621 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25656621 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 8957205 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 4034850 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 12154100 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12154100 — Surrogate Endpoint (SUR): Blood pressure
Study 23315447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23533227 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 22033354 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22033354 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22033354 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 22033354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20576793 — Predictive Biomarker (PRD): RNASEL mRNA
Genes: RNASEL; RNS4
Study 20576793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20576793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20576793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18035092 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12390708 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9702646 — Surrogate Endpoint (SUR): Blood pressure
Study 2913777 — Surrogate Endpoint (SUR): Blood pressure
Study 29650341 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23810377 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 23810377 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 21487640 — Surrogate Endpoint (SUR): Blood pressure
Study 28237860 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 28237860 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24894652 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24894652 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31150916 — Safety Biomarker (SAF): miR-375
Genes: MIR375
Study 21661431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 9416458 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 8297946 — Surrogate Endpoint (SUR): Blood pressure
Study 18386580 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8856584 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 8856584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7917580 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27180680 — Surrogate Endpoint (SUR): Blood pressure
Study 10493319 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10493319 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23617608 — Predictive Biomarker (PRD): PNN mRNA
Genes: PNN; DRS; MEMA
Study 12765745 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 1888325 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 1888325 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 31068332 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 26463607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6415511 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 25092393 — Surrogate Endpoint (SUR): Blood pressure
Study 21816445 — Predictive Biomarker (PRD): PDK2 mRNA
Genes: PDK2; PDHK2
Study 21816445 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4