TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17653509 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17653509 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17653509 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7502570 — Surrogate Endpoint (SUR): Blood pressure
Study 6988222 — Surrogate Endpoint (SUR): Blood pressure
Study 31058913 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6758744 — Surrogate Endpoint (SUR): Blood pressure
Study 30265168 — Surrogate Endpoint (SUR): Blood pressure
Study 24837493 — Safety Biomarker (SAF): Hyaluronic acid
Study 29804407 — Surrogate Endpoint (SUR): Blood pressure
Study 8923568 — Surrogate Endpoint (SUR): Blood pressure
Study 31048447 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 19396774 — Safety Biomarker (SAF): Hyaluronic acid
Study 17496391 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17496391 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 17496391 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12808272 — Surrogate Endpoint (SUR): Blood pressure
Study 7495249 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22653255 — Surrogate Endpoint (SUR): Serum creatinine
Study 22653255 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19270357 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 12119202 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8496328 — Surrogate Endpoint (SUR): Bone mineral density
Study 24637543 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21926600 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7933823 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 20535582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11551141 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 9381521 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 3794392 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 3794392 — Safety Biomarker (SAF): Succinate-semialdehyde dehydrogenase
Genes: ALDH5A1; SSADH
Study 12394920 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 12394920 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 7995742 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20150293 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20150293 — Surrogate Endpoint (SUR): Blood pressure
Study 30824559 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 19667948 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 19667948 — Surrogate Endpoint (SUR): Serum creatinine
Study 15932835 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11956508 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9605682 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9605682 — Surrogate Endpoint (SUR): Blood pressure
Study 22486138 — Surrogate Endpoint (SUR): Blood pressure
Study 16365696 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8363169 — Surrogate Endpoint (SUR): Serum creatinine
Study 30552272 — Surrogate Endpoint (SUR): Blood pressure
Study 26809652 — Predictive Biomarker (PRD): IFI30 mRNA
Genes: IFI30; GILT; IP30
Study 21091403 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 11602811 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11602811 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28481416 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 28481416 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28481416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28481416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27739188 — Predictive Biomarker (PRD): COMMD3 mRNA
Genes: COMMD3; BUP; C10orf8
Study 23557110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23557110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23557110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11888531 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9650015 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9650015 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28187952 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 15148493 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15148493 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7924173 — Surrogate Endpoint (SUR): Blood pressure
Study 838241 — Surrogate Endpoint (SUR): Blood pressure
Study 29357033 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 29357033 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 29357033 — Surrogate Endpoint (SUR): Blood pressure
Study 23091850 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17486065 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 17486065 — Predictive Biomarker (PRD): PAK1 mRNA
Genes: PAK1
Study 17486065 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 17486065 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2336525 — Predictive Biomarker (PRD): TNR mRNA
Genes: TNR
Study 25962383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21617110 — Surrogate Endpoint (SUR): Blood pressure
Study 10792199 — Surrogate Endpoint (SUR): Blood pressure
Study 2876122 — Surrogate Endpoint (SUR): Blood pressure
Study 30158072 — Surrogate Endpoint (SUR): Blood pressure
Study 12739832 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11789263 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11789263 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9383258 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9383258 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 18983789 — Surrogate Endpoint (SUR): Blood pressure
Study 16227473 — Surrogate Endpoint (SUR): Bone mineral density
Study 8909308 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 31119466 — Surrogate Endpoint (SUR): Serum uric acid
Study 28223407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23348636 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 19297102 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11378603 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 11378603 — Surrogate Endpoint (SUR): Serum creatinine
Study 9643403 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 19096961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30871921 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30871921 — Surrogate Endpoint (SUR): Serum potassium
Study 21677639 — Predictive Biomarker (PRD): NE
Study 21677639 — Surrogate Endpoint (SUR): Blood pressure
Study 15262911 — Surrogate Endpoint (SUR): Blood pressure
Study 11773294 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9564793 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31332977 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 16364159 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9059558 — Surrogate Endpoint (SUR): Bone mineral density
Study 20861328 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20861328 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 20861328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20861328 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20861328 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28280092 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28280092 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9288409 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 3015654 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 16859142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11148916 — Surrogate Endpoint (SUR): Blood pressure
Study 26724641 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26724641 — Predictive Biomarker (PRD): Hormone receptor
Study 1949366 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 19393473 — Surrogate Endpoint (SUR): Bone mineral density
Study 2853038 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26255288 — Surrogate Endpoint (SUR): Blood pressure
Study 26255288 — Surrogate Endpoint (SUR): Bone mineral density
Study 17052967 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10654491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10654491 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 10654491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8227822 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29705448 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29705448 — Surrogate Endpoint (SUR): Blood pressure
Study 31409166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31558379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31204416 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25392319 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study 25392319 — Predictive Biomarker (PRD): IRF6 mRNA
Genes: IRF6
Study 25392319 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 26021535 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9848785 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7814791 — Surrogate Endpoint (SUR): Blood pressure
Study 23237631 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 23237631 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23237631 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 23237631 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21290841 — Surrogate Endpoint (SUR): Blood pressure
Study 17876425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22985692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 21219582 — Surrogate Endpoint (SUR): Blood pressure
Study 19101221 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 11713618 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8698034 — Surrogate Endpoint (SUR): Blood pressure
Study 2711967 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 31166680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25771895 — Surrogate Endpoint (SUR): Blood pressure
Study 16788276 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 12628950 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10817062 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 26938814 — Surrogate Endpoint (SUR): Blood pressure
Study 26938814 — Surrogate Endpoint (SUR): Serum potassium
Study 21902621 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10999082 — Surrogate Endpoint (SUR): Blood pressure
Study 7237448 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31893396 — Surrogate Endpoint (SUR): Blood pressure
Study 17589294 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17589294 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15519186 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3221374 — Surrogate Endpoint (SUR): Blood pressure
Study 30231990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26418670 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 26418670 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 20534751 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19034033 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10867155 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10867155 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10867155 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3709641 — Surrogate Endpoint (SUR): Blood pressure
Study 27536947 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 27536947 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 21798721 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 25410066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25410066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21982875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21982875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21982875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7665721 — Predictive Biomarker (PRD): LNX1 mRNA
Genes: LNX1; LNX; PDZRN2; UNQ574/PRO1136
Study 23100042 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 19432498 — Surrogate Endpoint (SUR): Blood pressure
Study 10578975 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8767242 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 8767242 — Surrogate Endpoint (SUR): Blood pressure
Study 22307572 — Surrogate Endpoint (SUR): Serum testosterone
Study 16230074 — Monitoring Biomarker (MOI): HBV DNA
Study 2136775 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28391910 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24406614 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 20826257 — Safety Biomarker (SAF): Reactive oxygen species
Study 20826257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26645271 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 18364505 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3305087 — Surrogate Endpoint (SUR): Serum potassium
Study 16105815 — Surrogate Endpoint (SUR): Blood pressure
Study 10588623 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 23674606 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15525790 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 7850231 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24990113 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 24990113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 16619656 — Surrogate Endpoint (SUR): Blood pressure
Study 7719680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 7783656 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29112070 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29112070 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25162212 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29125703 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 22205605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22205605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16226044 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 16226044 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10464863 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10464863 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10464863 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 10464863 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7793217 — Surrogate Endpoint (SUR): Blood pressure
Study 1778085 — Surrogate Endpoint (SUR): Blood pressure
Study 1778085 — Surrogate Endpoint (SUR): Serum potassium
Study 7249547 — Surrogate Endpoint (SUR): Blood pressure
Study 7249547 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10592533 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 10592533 — Surrogate Endpoint (SUR): Sperm parameters
Study 8708166 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31747009 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21546857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17696259 — Monitoring Biomarker (MOI): HBV DNA
Study 31081522 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 15718288 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 6086974 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 30420184 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10334415 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2721334 — Surrogate Endpoint (SUR): Blood pressure
Study 23076338 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15845680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15845680 — Surrogate Endpoint (SUR): Blood pressure
Study 12887343 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 12887343 — Surrogate Endpoint (SUR): Probing pocket depth
Study 402795 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31568199 — Surrogate Endpoint (SUR): Bone mineral density
Study 11602220 — Surrogate Endpoint (SUR): Blood pressure
Study 3181323 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 23820000 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18198639 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 18198639 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18198639 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 18198639 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10073846 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31804699 — Predictive Biomarker (PRD): MARCKS mRNA
Genes: MARCKS; MACS; PRKCSL
Study 28280109 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26297883 — Predictive Biomarker (PRD): IMMT mRNA
Genes: IMMT; HMP; MIC60; MINOS2; PIG4; PIG52
Study 19396567 — Surrogate Endpoint (SUR): Serum creatinine
Study 16702472 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3679703 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12941676 — Surrogate Endpoint (SUR): Bone mineral density
Study 11899388 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28921547 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20708525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20708525 — Surrogate Endpoint (SUR): Blood pressure
Study 20708525 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12110425 — Surrogate Endpoint (SUR): Bone mineral density
Study 7818312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2127687 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 22516427 — Surrogate Endpoint (SUR): Blood pressure
Study 12672933 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12153550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3145585 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3145585 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 27234930 — Surrogate Endpoint (SUR): Blood pressure
Study 27234930 — Surrogate Endpoint (SUR): Serum creatinine
Study 18332474 — Predictive Biomarker (PRD): Hormone receptor
Study 8928757 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27565858 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 27565858 — Safety Biomarker (SAF): Hyaluronic acid
Study 3568934 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 3568934 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3568934 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 3568934 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 29855175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1667755 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 1667755 — Predictive Biomarker (PRD): Intact parathyroid hormone