TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02766530 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study NCT03710395 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study NCT03710395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT02280265 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT00209417 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01723111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03691467 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01741805 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00458081 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02175641 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00479882 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00479882 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05095753 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01641952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03027401 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00643968 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06061510 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT06061510 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06061510 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03640260 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT03382990 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT03300505 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04651790 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01569568 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT02766803 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02650648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04910893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04079699 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT02783196 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT02783196 — Predictive Biomarker (PRD): BMAL1 mRNA
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study NCT02783196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00361543 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04560270 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04560270 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04349189 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03447301 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02814981 — Safety Biomarker (SAF): KCNH2
Genes: Kv11.1; HERG; erg1
Study NCT02517697 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03658031 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03433469 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03097731 — Predictive Biomarker (PRD): IL10RA mRNA
Genes: IL10RA; IL10R
Study NCT05466825 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05466825 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03594448 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT03594448 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03444064 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03711422 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03834324 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT03074097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03332043 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02906436 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02906436 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00588692 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03370744 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02076646 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01459445 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT03641313 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01227980 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03072264 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study NCT00397384 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00397384 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01217762 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01217762 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03777098 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT03532659 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06390839 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT06390839 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT03735797 — Predictive Biomarker (PRD): ARID5B mRNA
Genes: ARID5B; DESRT; MRF2
Study NCT03735797 — Predictive Biomarker (PRD): SALL4 mRNA
Genes: SALL4; ZNF797
Study NCT04174001 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02473289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01680861 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT01680861 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT01680861 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01966822 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04365634 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02315326 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01828008 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05888636 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT05888636 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT05888636 — Predictive Biomarker (PRD): TENT5C mRNA
Genes: TENT5C; FAM46C
Study NCT05888636 — Predictive Biomarker (PRD): DIS3 mRNA
Genes: DIS3; KIAA1008; RRP44
Study NCT05888636 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT03863015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00749957 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT03167268 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03167268 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03167268 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT03167268 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03167268 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00443170 — Predictive Biomarker (PRD): DYRK3 mRNA
Genes: DYRK3
Study NCT02228733 — Surrogate Endpoint (SUR): Serum potassium
Study NCT04327102 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02637583 — Predictive Biomarker (PRD): ST14 mRNA
Genes: ST14; PRSS14; SNC19; TADG15
Study NCT02893241 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02300363 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT06440148 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study NCT03651089 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03715933 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study NCT03878615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02348125 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04236388 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00471341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00471341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00223184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00223184 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT00223184 — Predictive Biomarker (PRD): TWIST1 mRNA
Genes: TWIST1; BHLHA38; TWIST
Study NCT03529682 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT01810458 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT03491891 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT02108964 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04271956 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04271956 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03664804 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04348864 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01293253 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04332107 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04605289 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study NCT00376207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00376207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00376207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01635231 — Predictive Biomarker (PRD): SLC12A1 mRNA
Genes: SLC12A1; NKCC2
Study NCT00960323 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03202407 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03202407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04423094 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT04423094 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT04423094 — Predictive Biomarker (PRD): ETNPPL mRNA
Genes: ETNPPL; AGXT2L1
Study NCT04423094 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study NCT01920477 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00004853 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT01718808 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00693745 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00693745 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02274792 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02534415 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01636635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03518294 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03518294 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study NCT03892122 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00995202 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04601012 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02347540 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study NCT03211234 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01524484 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01799473 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00605436 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03004001 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04020315 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04020315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04020315 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT04020315 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01225094 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02634333 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02634333 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02037477 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03194893 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03194893 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT04394377 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01049451 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02686177 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study NCT02686177 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study NCT00449618 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04341714 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03181607 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03624101 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00703417 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04517097 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01478490 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01215487 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01215487 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01215487 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00092534 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01660386 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00412412 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01071655 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01071655 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT00733876 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00957268 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03951298 — Predictive Biomarker (PRD): WFS1 mRNA
Genes: WFS1
Study NCT02086877 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01219907 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04419298 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT01390727 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01344902 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study NCT01842919 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01890798 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02105116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT01482689 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study NCT01482689 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT00821340 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT03762031 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01003899 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01125046 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01815749 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01815749 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT01815749 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00002950 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03603665 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT03542409 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study NCT03162224 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT03162224 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02619903 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT03905655 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04461899 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02423512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02238262 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01780038 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study NCT04160546 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04160546 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03235401 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01279928 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00340587 — Predictive Biomarker (PRD): ZP2 mRNA
Genes: ZP2; ZPA
Study NCT00340587 — Predictive Biomarker (PRD): ZP3 mRNA
Genes: ZP3; ZP3A; ZP3B; ZPC
Study NCT03981705 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05520853 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05520853 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05520853 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT02760095 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study NCT02964533 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03950271 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01082692 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01416402 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03736122 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study NCT01365481 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02086240 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT04067726 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT03007030 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT03727555 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT04140500 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04140500 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study NCT00672464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00821886 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00821886 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01986764 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01986764 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02734953 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02734953 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02546921 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT01167491 — Predictive Biomarker (PRD): TYROBP mRNA
Genes: TYROBP; DAP12; KARAP
Study NCT02186600 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01504477 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01504477 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00644670 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04281602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04281602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01515059 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01515059 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00222872 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03058575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03058575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00529399 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03236701 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT01022112 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03453268 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01743989 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01743989 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01741103 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26