TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23292315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15047680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20112821 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9272427 — Surrogate Endpoint (SUR): Bone mineral density
Study 27513651 — Surrogate Endpoint (SUR): Blood pressure
Study 27513651 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23844570 — Surrogate Endpoint (SUR): Blood pressure
Study 30661687 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 15464258 — Predictive Biomarker (PRD): PARP9 mRNA
Genes: PARP9; BAL; BAL1
Study 31744798 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31744798 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27784687 — Surrogate Endpoint (SUR): Blood pressure
Study 9552063 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 8151464 — Surrogate Endpoint (SUR): Serum calcium
Study 17591563 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 23141816 — Surrogate Endpoint (SUR): Blood pressure
Study 15219265 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9385624 — Surrogate Endpoint (SUR): Blood pressure
Study 28408067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23937144 — Surrogate Endpoint (SUR): Blood pressure
Study 22788842 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22788842 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12607659 — Surrogate Endpoint (SUR): Serum creatinine
Study 10232435 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 10232435 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7057465 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24388622 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30092827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27804264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23992556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23992556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23992556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23992556 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 11333166 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11333166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11333166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3295035 — Surrogate Endpoint (SUR): Blood pressure
Study 31119481 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22118479 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11207651 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7596767 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8988699 — Surrogate Endpoint (SUR): Bone mineral density
Study 8988699 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8988699 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29740097 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 18814452 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 12114372 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 15983916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15983916 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11915001 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24152757 — Surrogate Endpoint (SUR): Blood pressure
Study 19056576 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 19056576 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 9716578 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 7021163 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28652048 — Surrogate Endpoint (SUR): Bone mineral density
Study 23228972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9766795 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28061321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28061321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21129746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11231977 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28318867 — Surrogate Endpoint (SUR): Bone mineral density
Study 21378250 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16609087 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12969165 — Surrogate Endpoint (SUR): Blood pressure
Study 8627642 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1471706 — Surrogate Endpoint (SUR): Blood pressure
Study 26919080 — Predictive Biomarker (PRD): RARB mRNA
Genes: RARB; HAP; NR1B2
Study 12124481 — Predictive Biomarker (PRD): CEACAM6 mRNA
Genes: CEACAM6; NCA
Study 30707761 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21470361 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 11281235 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11281235 — Surrogate Endpoint (SUR): Blood pressure
Study 31179008 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20446252 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15830637 — Safety Biomarker (SAF): Interleukin 1
Study 14655739 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10786218 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 1833126 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 1833126 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 6285744 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 20659948 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 2015395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26355168 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 19241361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19241361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19241361 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 19241361 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18039105 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 26773917 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20430686 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 28862406 — Surrogate Endpoint (SUR): Blood pressure
Study 2552342 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17028770 — Predictive Biomarker (PRD): Hormone receptor
Study 9314450 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8400255 — Surrogate Endpoint (SUR): Serum creatinine
Study 17653243 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17653243 — Surrogate Endpoint (SUR): Blood pressure
Study 15799687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24828894 — Surrogate Endpoint (SUR): Blood pressure
Study 20979909 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8907724 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 28566209 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 28566209 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 31393399 — Surrogate Endpoint (SUR): Bone mineral density
Study 11116103 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11116103 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27822448 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 8243223 — Surrogate Endpoint (SUR): Blood pressure
Study 27697447 — Surrogate Endpoint (SUR): Blood pressure
Study 16613261 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 16613261 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27150293 — Predictive Biomarker (PRD): TTMP mRNA
Genes: TTMP; C3orf52
Study 27150293 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20012550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20012550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28183314 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28183314 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25982678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25982678 — Surrogate Endpoint (SUR): Blood pressure
Study 10843478 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25296741 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23118007 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17614015 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24028708 — Surrogate Endpoint (SUR): Serum calcium
Study 20888994 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29510745 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24649895 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 11896508 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11896508 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11896508 — Surrogate Endpoint (SUR): Blood pressure
Study 23469944 — Predictive Biomarker (PRD): SAA4 mRNA
Genes: SAA4; CSAA
Study 23469944 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 9135853 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 7994447 — Surrogate Endpoint (SUR): Blood pressure
Study 7994447 — Surrogate Endpoint (SUR): Serum potassium
Study 10064003 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 10064003 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10064003 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2475688 — Surrogate Endpoint (SUR): Blood pressure
Study 22842339 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20047847 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15761751 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12718708 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 7946771 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18582254 — Surrogate Endpoint (SUR): Serum creatinine
Study 15975729 — Surrogate Endpoint (SUR): Blood pressure
Study 11821704 — Surrogate Endpoint (SUR): Blood pressure
Study 31740083 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 8609254 — Surrogate Endpoint (SUR): Serum calcium
Study 28899771 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7648483 — Surrogate Endpoint (SUR): Bone mineral density
Study 31724212 — Monitoring Biomarker (MOI): HBV DNA
Study 24482066 — Surrogate Endpoint (SUR): Serum creatinine
Study 20040610 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12875092 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 27832140 — Predictive Biomarker (PRD): BCAR1 mRNA
Genes: BCAR1; CAS; CASS1; CRKAS
Study 18399759 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28451931 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26178720 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11092464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11092464 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 11092464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30958851 — Surrogate Endpoint (SUR): Blood pressure
Study 26115796 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7657042 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 27941110 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 22089326 — Surrogate Endpoint (SUR): Blood pressure
Study 11520775 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 11520775 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31573637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26369655 — Predictive Biomarker (PRD): CDX2 mRNA
Genes: CDX2; CDX3
Study 26369655 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 9918478 — Surrogate Endpoint (SUR): Blood pressure
Study 9918478 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8787955 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 2286486 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29151416 — Surrogate Endpoint (SUR): Blood pressure
Study 19028780 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 16880785 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 16880785 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 7957152 — Surrogate Endpoint (SUR): Plasma ammonia
Study 23085729 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21558574 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21558574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21558574 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9248981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9248981 — Safety Biomarker (SAF): Interleukin 1
Study 3135572 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23357657 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 15226212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11789166 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30377381 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 11410822 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9757157 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31658212 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1292340 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31221620 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 31221620 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 31221620 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30459247 — Predictive Biomarker (PRD): FFAR1 mRNA
Genes: FFAR1; GPR40
Study 26937646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31930845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31930845 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 31930845 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31930845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24570490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21484276 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 16508777 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16508777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2847928 — Surrogate Endpoint (SUR): Blood pressure
Study 29735484 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29735484 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29735484 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26822398 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26822398 — Predictive Biomarker (PRD): Hormone receptor
Study 19423131 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15255788 — Surrogate Endpoint (SUR): Blood pressure
Study 28167659 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 28167659 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 21446892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21446892 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21446892 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17938986 — Surrogate Endpoint (SUR): New morphometric vertebral fractures
Study 17938986 — Surrogate Endpoint (SUR): Bone mineral density
Study 16542484 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16542484 — Surrogate Endpoint (SUR): Blood pressure
Study 16990992 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 3018822 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25854535 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24557728 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22999808 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18294310 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27990219 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27990219 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20597833 — Surrogate Endpoint (SUR): Blood pressure
Study 15781815 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 15781815 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1632542 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30121146 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22112807 — Surrogate Endpoint (SUR): Blood pressure
Study 17697555 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 28392807 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 26611245 — Surrogate Endpoint (SUR): Blood pressure
Study 17458505 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9657626 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31362081 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3304370 — Surrogate Endpoint (SUR): Blood pressure
Study 27898068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27898068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27898068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20004480 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 11770694 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 9657461 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 9657461 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9657461 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2697729 — Surrogate Endpoint (SUR): Blood pressure
Study 28616851 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28616851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26116037 — Surrogate Endpoint (SUR): Blood pressure
Study 22352122 — Surrogate Endpoint (SUR): Blood pressure
Study 19153936 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19153936 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19153936 — Surrogate Endpoint (SUR): Blood pressure
Study 24509962 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 7641720 — Surrogate Endpoint (SUR): Blood pressure
Study 2475699 — Surrogate Endpoint (SUR): Blood pressure
Study 26579797 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26579797 — Surrogate Endpoint (SUR): Blood pressure
Study 21787474 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17014519 — Surrogate Endpoint (SUR): Blood pressure
Study 17014519 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26451734 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 20438516 — Monitoring Biomarker (MOI): Cell-free DNA