TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22684655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22684655 — Surrogate Endpoint (SUR): Serum creatinine
Study 22685032 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 22685032 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 22685032 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 22685225 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 22689675 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 22689675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22691114 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22693172 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 22693229 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22695105 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22696176 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22696435 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22696435 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22699693 — Surrogate Endpoint (SUR): Blood pressure
Study 22700780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22701542 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 22701615 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22701615 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22701615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22704876 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 22707516 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22707516 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22709477 — Surrogate Endpoint (SUR): Blood pressure
Study 22713099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22713099 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22716943 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22716943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22716943 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22717743 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 22717743 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22719020 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 22719806 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 22719806 — Surrogate Endpoint (SUR): Blood pressure
Study 22719881 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22719975 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 22719975 — Safety Biomarker (SAF): miR-15a
Genes: MIR15A
Study 22719975 — Safety Biomarker (SAF): miR-16
Study 22719975 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 22721944 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22721944 — Surrogate Endpoint (SUR): Blood pressure
Study 22721971 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 22721971 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22722755 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 22722755 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22722778 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22723326 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 22730482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22730482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22733020 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22734012 — Predictive Biomarker (PRD): DCX mRNA
Genes: DCX; DBCN; LISX
Study 22734071 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22734817 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22734817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22735793 — Surrogate Endpoint (SUR): Blood pressure
Study 22739576 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22740718 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22740718 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 22742719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22742719 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22743310 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 22745608 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22747613 — Surrogate Endpoint (SUR): Serum potassium
Study 22747660 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 22748805 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22748805 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 22751595 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 22751595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22751595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22759444 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22759444 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 22761257 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 22761257 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 22762561 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22762711 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22763609 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 22764211 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22764211 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 22773528 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 22775568 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 22775568 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 22776426 — Predictive Biomarker (PRD): TTK mRNA
Genes: TTK; MPS1; MPS1L1
Study 22776426 — Predictive Biomarker (PRD): LY6K mRNA
Genes: LY6K; CO16
Study 22777623 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22780885 — Surrogate Endpoint (SUR): Blood pressure
Study 22780919 — Predictive Biomarker (PRD): GSC mRNA
Genes: GSC
Study 22780919 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22781225 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22784036 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 22784116 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 22784116 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 22785351 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22786877 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 22789619 — Safety Biomarker (SAF): Reactive oxygen species
Study 22790832 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 22790881 — Surrogate Endpoint (SUR): Blood pressure
Study 22795276 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22795276 — Surrogate Endpoint (SUR): Blood pressure
Study 22795984 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22803961 — Surrogate Endpoint (SUR): Blood pressure
Study 22804876 — Surrogate Endpoint (SUR): Serum testosterone
Study 22805291 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 22805291 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study 22805466 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22809118 — Monitoring Biomarker (MOI): Procalcitonin
Study 22809118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22810810 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 22811928 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22813607 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 22815703 — Safety Biomarker (SAF): RFC1
Genes: A1; PO-GA; RFC140; MHCBFB
Study 22817698 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 22817698 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22817698 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22819172 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22821614 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22824238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22824238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22824238 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22825216 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 22825536 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22826079 — Surrogate Endpoint (SUR): Blood pressure
Study 22828668 — Surrogate Endpoint (SUR): Blood pressure
Study 22829110 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 22829110 — Predictive Biomarker (PRD): ZAP70 mRNA
Genes: ZAP70; SRK
Study 22829110 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 22829110 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22829629 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 22829920 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22829920 — Safety Biomarker (SAF): Reactive oxygen species
Study 22829920 — Safety Biomarker (SAF): Cytochrome c
Study 22830581 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 22830581 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22830581 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22837004 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22837373 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22837373 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 22837373 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 22837378 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 22837378 — Predictive Biomarker (PRD): HTR4 mRNA
Genes: HTR4
Study 22837378 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 22837378 — Predictive Biomarker (PRD): ADAM19 mRNA
Genes: ADAM19; MLTNB; FKSG34
Study 22837378 — Predictive Biomarker (PRD): RARB mRNA
Genes: RARB; HAP; NR1B2
Study 22837378 — Predictive Biomarker (PRD): PLPP3 mRNA
Genes: PLPP3; LPP3; PPAP2B
Study 22837378 — Predictive Biomarker (PRD): ADAMTS19 mRNA
Genes: ADAMTS19
Study 22837492 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22838970 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22839200 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22839200 — Predictive Biomarker (PRD): Hormone receptor
Study 22848407 — Surrogate Endpoint (SUR): Bone mineral density
Study 22848407 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 22848407 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22853816 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22855388 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 22856551 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22856551 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22859235 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22859235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22860080 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22860080 — Monitoring Biomarker (MOI): HBV DNA
Study 22865914 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22865914 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 22865914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22869821 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 22871833 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22871833 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 22871833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22871833 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22874520 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22874520 — Surrogate Endpoint (SUR): Blood pressure
Study 22875627 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 22875627 — Predictive Biomarker (PRD): P2RY8 mRNA
Genes: P2RY8
Study 22875627 — Predictive Biomarker (PRD): CRLF2 mRNA
Genes: CRLF2; CRL2; ILXR; TSLPR
Study 22877812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22877866 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22877866 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 22878519 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22878519 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22878551 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22878784 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22880942 — Surrogate Endpoint (SUR): Blood pressure
Study 22882209 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22882209 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22883224 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 22883224 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22883740 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 22884544 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 22884685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22884685 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22884879 — Predictive Biomarker (PRD): GRM7 mRNA
Genes: GRM7; GPRC1G; MGLUR7
Study 22892920 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22894827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22894827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22894827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22894827 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 22895887 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 22896000 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 22897944 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 22897944 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22897944 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22899766 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22901459 — Safety Biomarker (SAF): Interleukin 1
Study 22901459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22901741 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 22901847 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 22903006 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22909342 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22911697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22911697 — Safety Biomarker (SAF): Hyaluronic acid
Study 22911730 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 22911730 — Predictive Biomarker (PRD): ELOVL1 mRNA
Genes: ELOVL1; SSC1; CGI-88
Study 22913682 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22913682 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22913891 — Surrogate Endpoint (SUR): Blood pressure
Study 22913891 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22915641 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 22915641 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 22915641 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 22915656 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22915656 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 22916254 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 22916254 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22922531 — Safety Biomarker (SAF): Fibroblast growth factor 1
Genes: FGF1
Study 22922531 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22924536 — Predictive Biomarker (PRD): ATP1A3 mRNA
Genes: ATP1A3
Study 22927248 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 22927248 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 22927248 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 22927452 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 22927751 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22931751 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22932225 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22932256 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22932804 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 22932804 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 22932804 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22932804 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22933539 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22933539 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22935398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22935398 — Surrogate Endpoint (SUR): Blood pressure
Study 22936711 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22939663 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22939945 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22939945 — Safety Biomarker (SAF): BDNF
Study 22940027 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 22940371 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22941123 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22941123 — Predictive Biomarker (PRD): BCAR1 mRNA
Genes: BCAR1; CAS; CASS1; CRKAS
Study 22941849 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 22942205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22946546 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22952794 — Surrogate Endpoint (SUR): Blood pressure
Study 22954507 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 22955317 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22955317 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 22955317 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 22955514 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 22958032 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22959186 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22959186 — Monitoring Biomarker (MOI): Angiopoietin 1 receptor
Genes: TEK; TIE2; VMCM; VMCM1
Study 22961865 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22961865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22961865 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2