TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8832535 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 22818063 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 17311545 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17311545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17311545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8131523 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 24101053 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24101053 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24101053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24101053 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2948256 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20377770 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20377770 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17163250 — Surrogate Endpoint (SUR): Blood pressure
Study 14583239 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31475494 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 31475494 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31475494 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12152675 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 12152675 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 412041 — Surrogate Endpoint (SUR): Blood pressure
Study 16430107 — Surrogate Endpoint (SUR): Blood pressure
Study 10191298 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 10191298 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29040589 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 25646321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25646321 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23337405 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 27813716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 12925453 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 1421065 — Surrogate Endpoint (SUR): Blood pressure
Study 24818336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25613105 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 20854930 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22260337 — Surrogate Endpoint (SUR): Blood pressure
Study 19594293 — Surrogate Endpoint (SUR): Bone mineral density
Study 1586706 — Surrogate Endpoint (SUR): Hematologic response
Study 3838725 — Surrogate Endpoint (SUR): Blood pressure
Study 27882007 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 6870998 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16278088 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 7395656 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 28598285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19159632 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 19159632 — Safety Biomarker (SAF): Reactive oxygen species
Study 17317022 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9625576 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31976786 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study 31976786 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 28681902 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 26606405 — Predictive Biomarker (PRD): POLM mRNA
Genes: POLM; polmu
Study 7528032 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25005937 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 25005937 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 25005937 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 25005937 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 10190392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2310652 — Surrogate Endpoint (SUR): Blood pressure
Study 28199305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18952242 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17531571 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 17531571 — Surrogate Endpoint (SUR): Blood pressure
Study 21849285 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17666348 — Surrogate Endpoint (SUR): Blood pressure
Study 15310631 — Surrogate Endpoint (SUR): Blood pressure
Study 14967373 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 205382 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 14747881 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14747881 — Surrogate Endpoint (SUR): Blood pressure
Study 8857326 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 19765953 — Surrogate Endpoint (SUR): Serum calcium
Study 10439731 — Surrogate Endpoint (SUR): Blood pressure
Study 388402 — Surrogate Endpoint (SUR): Blood pressure
Study 388402 — Surrogate Endpoint (SUR): Serum potassium
Study 388402 — Surrogate Endpoint (SUR): Serum creatinine
Study 388402 — Surrogate Endpoint (SUR): Serum uric acid
Study 31470813 — Surrogate Endpoint (SUR): Blood pressure
Study 30030717 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 27001081 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22917728 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 1986509 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22828087 — Predictive Biomarker (PRD): MOBP mRNA
Genes: MOBP
Study 22828087 — Surrogate Endpoint (SUR): Blood pressure
Study 6498122 — Surrogate Endpoint (SUR): Blood pressure
Study 25332321 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1491396 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20558755 — Surrogate Endpoint (SUR): Blood pressure
Study 17377860 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 29906570 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27713633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27713633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12819512 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10903599 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10903599 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10903599 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 8752803 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22162508 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 22520733 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22520733 — Predictive Biomarker (PRD): Hormone receptor
Study 22520733 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19862578 — Surrogate Endpoint (SUR): Blood pressure
Study 17928625 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15647105 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15647105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11901939 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11901939 — Surrogate Endpoint (SUR): Blood pressure
Study 8281697 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26415375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26415375 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22044691 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11581138 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3232497 — Surrogate Endpoint (SUR): Blood pressure
Study 28648698 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19791470 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16828596 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 30427250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30427250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30427250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12464949 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28668686 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28668686 — Surrogate Endpoint (SUR): Serum creatinine
Study 27589688 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27589688 — Predictive Biomarker (PRD): GP2 mRNA
Genes: GP2
Study 27589688 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20969925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26860514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17158412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17158412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3110845 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29643338 — Surrogate Endpoint (SUR): Blood pressure
Study 26766930 — Surrogate Endpoint (SUR): Blood pressure
Study 22391106 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 18685511 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 17681825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16432294 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16432294 — Surrogate Endpoint (SUR): Blood pressure
Study 10710871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3872082 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 24377413 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 21965459 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20671225 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20671225 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2360387 — Surrogate Endpoint (SUR): Blood pressure
Study 25841542 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23478192 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 18050183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25344738 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 25344738 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 22955258 — Pharmacodynamic Biomarker (PDY): Pyruvate dehydrogenase kinase 1
Genes: PDK1; PDHK1
Study 16025972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 380732 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9220522 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31601214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11697019 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21270839 — Surrogate Endpoint (SUR): Blood pressure
Study 25104521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25104521 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17588584 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27840322 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 22435991 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20159133 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12499889 — Surrogate Endpoint (SUR): Blood pressure
Study 12499889 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12499889 — Surrogate Endpoint (SUR): Serum creatinine
Study 9462602 — Surrogate Endpoint (SUR): Blood pressure
Study 8575118 — Surrogate Endpoint (SUR): Blood pressure
Study 8575118 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2213283 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2213283 — Surrogate Endpoint (SUR): Blood pressure
Study 19487926 — Safety Biomarker (SAF): Reactive oxygen species
Study 16730270 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11520524 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11520524 — Surrogate Endpoint (SUR): Blood pressure
Study 8326293 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8326293 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21397541 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 9350068 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25912040 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 8084972 — Surrogate Endpoint (SUR): Blood pressure
Study 21857142 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21857142 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21857142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19216014 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17926823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8128835 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 3651264 — Predictive Biomarker (PRD): EDAR mRNA
Genes: EDAR; DL
Study 26021563 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28919811 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 23392882 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21843919 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17244641 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30194765 — Surrogate Endpoint (SUR): Blood pressure
Study 25495109 — Surrogate Endpoint (SUR): Blood pressure
Study 25495109 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18281656 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 12676601 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10760528 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 1424429 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 29921339 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22797101 — Surrogate Endpoint (SUR): Serum creatinine
Study 11669594 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16620353 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14960129 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 27028380 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 20610442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25651367 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21804283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21804283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21804283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11226005 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 23078574 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11916764 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 11916764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11916764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1981075 — Surrogate Endpoint (SUR): Blood pressure
Study 25431280 — Surrogate Endpoint (SUR): Blood pressure
Study 24658707 — Surrogate Endpoint (SUR): Serum creatinine
Study 542823 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31834252 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31834252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17395677 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23422495 — Surrogate Endpoint (SUR): Serum creatinine
Study 17182126 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9643615 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31546738 — Surrogate Endpoint (SUR): Blood pressure
Study 28454836 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31446217 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15221507 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28121670 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26192006 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 21343579 — Surrogate Endpoint (SUR): Bone mineral density
Study 16392026 — Surrogate Endpoint (SUR): Bone mineral density
Study 15164191 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 11152791 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23292928 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 20825712 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 18094315 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 29615088 — Predictive Biomarker (PRD): RHOJ mRNA
Genes: RHOJ; ARHJ; RASL7B; RHOI; TCL
Study 27179112 — Predictive Biomarker (PRD): FCGR2A mRNA
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 27179112 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 27179112 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27179112 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24899618 — Predictive Biomarker (PRD): MVB12B mRNA
Genes: MVB12B; C9orf28; FAM125B
Study 21384066 — Surrogate Endpoint (SUR): Blood pressure
Study 9162432 — Surrogate Endpoint (SUR): Blood pressure
Study 16860976 — Surrogate Endpoint (SUR): Blood pressure
Study 16009907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2189040 — Surrogate Endpoint (SUR): Blood pressure
Study 23461895 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 18036359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18036359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18036359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2076408 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9554680 — Surrogate Endpoint (SUR): Blood pressure
Study 9554680 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11300610 — Surrogate Endpoint (SUR): Blood pressure
Study 31302249 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 31302249 — Predictive Biomarker (PRD): HSPA1A mRNA
Genes: HSPA1A; HSP72; HSPA1; HSX70
Study 31302249 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 31302249 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 30625106 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18326331 — Surrogate Endpoint (SUR): Blood pressure
Study 10068849 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 24528783 — Surrogate Endpoint (SUR): Blood pressure
Study 15083312 — Surrogate Endpoint (SUR): Blood pressure
Study 15083312 — Surrogate Endpoint (SUR): Serum calcium
Study 12133516 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19937427 — Surrogate Endpoint (SUR): Bone mineral density
Study 18415823 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9470081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9470081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2