TrialPanorama/TrialPanorama-database huggingface dataset:
Study 2179146 — Surrogate Endpoint (SUR): Blood pressure
Study 2561281 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19299427 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19299427 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2567717 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 2567717 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 27412188 — Surrogate Endpoint (SUR): Blood pressure
Study 25262306 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25262306 — Surrogate Endpoint (SUR): Blood pressure
Study 7769807 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7769807 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7769807 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7769807 — Surrogate Endpoint (SUR): Blood pressure
Study 2022712 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2022712 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 28919328 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study 17329991 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 19035101 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 27155741 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 27155741 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 22416676 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22416676 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 22416676 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 22416676 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22416676 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 22416676 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22416676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22416676 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22416676 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15955382 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10215734 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 7887385 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23494931 — Surrogate Endpoint (SUR): Serum testosterone
Study 19689171 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 16949830 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10818079 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10818079 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 10818079 — Surrogate Endpoint (SUR): Blood pressure
Study 30625070 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 30625070 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26731754 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26731754 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24215845 — Predictive Biomarker (PRD): GSTA1 mRNA
Genes: GSTA1
Study 30022759 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16060124 — Surrogate Endpoint (SUR): Serum creatinine
Study 19810125 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 19810125 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 23552821 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9390615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9390615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9390615 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 9390615 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 3579008 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27720942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16364549 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 19364991 — Surrogate Endpoint (SUR): Blood pressure
Study 11266263 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 11266263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11266263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10068082 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7736480 — Surrogate Endpoint (SUR): Blood pressure
Study 22649299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21244805 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9161744 — Surrogate Endpoint (SUR): Serum potassium
Study 3122275 — Surrogate Endpoint (SUR): Blood pressure
Study 21969418 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 21029641 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15516362 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 15516362 — Surrogate Endpoint (SUR): Blood pressure
Study 10415055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10415055 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 2255726 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 25332071 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 21116816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2515306 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 24401240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24401240 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24401240 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 24401240 — Surrogate Endpoint (SUR): Serum sodium
Study 24401240 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24401240 — Surrogate Endpoint (SUR): Blood pressure
Study 19896353 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10450833 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10450833 — Surrogate Endpoint (SUR): Serum potassium
Study 10450833 — Surrogate Endpoint (SUR): Blood pressure
Study 8931972 — Surrogate Endpoint (SUR): Blood pressure
Study 1869063 — Surrogate Endpoint (SUR): Blood pressure
Study 2066644 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 17261395 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8755835 — Predictive Biomarker (PRD): RAPH1 mRNA
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 1862210 — Predictive Biomarker (PRD): HPDL mRNA
Genes: HPDL; GLOXD1
Study 30661255 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30661255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12659466 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12659466 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26478225 — Surrogate Endpoint (SUR): Bone mineral density
Study 26478225 — Surrogate Endpoint (SUR): Serum calcium
Study 26478225 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 22777865 — Surrogate Endpoint (SUR): Bone mineral density
Study 23515409 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23515409 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11349839 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11349839 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 10776821 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8087329 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2221314 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2221314 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 16126025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16126025 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11991367 — Surrogate Endpoint (SUR): Blood pressure
Study 7768573 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9429053 — Predictive Biomarker (PRD): RORC mRNA
Genes: RORC; NR1F3; RORG; RZRG
Study 23839729 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 8797480 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 28980368 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27208972 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 25294957 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 25294957 — Pharmacodynamic Biomarker (PDY): Interferon regulatory factor 3
Genes: IRF3
Study 17493477 — Surrogate Endpoint (SUR): Blood pressure
Study 17493477 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2188763 — Surrogate Endpoint (SUR): Blood pressure
Study 25563826 — Surrogate Endpoint (SUR): Serum creatinine
Study 25563826 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25563826 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21120480 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10692004 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 10692004 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8259343 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8259343 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 8259343 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 3896665 — Surrogate Endpoint (SUR): Blood pressure
Study 30466512 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25514302 — Monitoring Biomarker (MOI): HBV DNA
Study 29189607 — Predictive Biomarker (PRD): SECTM1 mRNA
Genes: SECTM1; K12
Study 29189607 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 18055869 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 16476713 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 16476713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26211378 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23541425 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 21852546 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 12413642 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10705175 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 22334531 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22334531 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12743626 — Surrogate Endpoint (SUR): Blood pressure
Study 12743626 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25023641 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 31505191 — Surrogate Endpoint (SUR): Blood pressure
Study 21091860 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 17554147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17554147 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8807140 — Surrogate Endpoint (SUR): Blood pressure
Study 12610799 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12610799 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 20923540 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20923540 — Surrogate Endpoint (SUR): Blood pressure
Study 15353828 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26119403 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 8701417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2858743 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 26684248 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24255129 — Surrogate Endpoint (SUR): Blood pressure
Study 24255129 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 12449159 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 1649874 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29920594 — Surrogate Endpoint (SUR): Blood pressure
Study 24979398 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 22024564 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 22024564 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 22024564 — Surrogate Endpoint (SUR): Bone mineral density
Study 19901111 — Predictive Biomarker (PRD): Hormone receptor
Study 8535552 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8535552 — Surrogate Endpoint (SUR): Blood pressure
Study 23511692 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 19075138 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 19075138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24206459 — Surrogate Endpoint (SUR): Blood pressure
Study 18927168 — Surrogate Endpoint (SUR): Blood pressure
Study 15521869 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15521869 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 11172164 — Surrogate Endpoint (SUR): Bone mineral density
Study 22429658 — Surrogate Endpoint (SUR): Blood pressure
Study 15051633 — Safety Biomarker (SAF): Interleukin 1
Study 216235 — Surrogate Endpoint (SUR): Blood pressure
Study 31418140 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27899322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19826188 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 19826188 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 16962480 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11372037 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 29874180 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29874180 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29874180 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29874180 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10593470 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 10593470 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29237679 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23928735 — Predictive Biomarker (PRD): CES2 mRNA
Genes: CES2; ICE
Study 20969665 — Safety Biomarker (SAF): Hyaluronic acid
Study 22105592 — Surrogate Endpoint (SUR): Serum creatinine
Study 12801622 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12801622 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12801622 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15925286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9232448 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8453021 — Surrogate Endpoint (SUR): Blood pressure
Study 29527709 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 24430319 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31746877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25368995 — Surrogate Endpoint (SUR): Serum testosterone
Study 22974804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19890632 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19890632 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17917313 — Surrogate Endpoint (SUR): Blood pressure
Study 15388511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15388511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2182939 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2182939 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19561422 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 17339550 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1864315 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1864315 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 6638543 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 6638543 — Surrogate Endpoint (SUR): Blood pressure
Study 22113368 — Surrogate Endpoint (SUR): Blood pressure
Study 22113368 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17324009 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 11935151 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11935151 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11935151 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7587232 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 7875765 — Surrogate Endpoint (SUR): Blood pressure
Study 2361891 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 12610035 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10498559 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2006659 — Surrogate Endpoint (SUR): Blood pressure
Study 2006659 — Surrogate Endpoint (SUR): Serum creatinine
Study 26561613 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22769574 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15231900 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15231900 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9221708 — Surrogate Endpoint (SUR): Blood pressure
Study 8133796 — Surrogate Endpoint (SUR): Bone mineral density
Study 23300301 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23300301 — Safety Biomarker (SAF): Interleukin 1
Study 23300301 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21426372 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 21426372 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21426372 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 21426372 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 19628647 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19628647 — Surrogate Endpoint (SUR): Serum creatinine
Study 15633617 — Surrogate Endpoint (SUR): Blood pressure
Study 9754844 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 16273807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11840671 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11026650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7146263 — Surrogate Endpoint (SUR): Blood pressure
Study 31158739 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18981485 — Surrogate Endpoint (SUR): Bone mineral density
Study 18981485 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18981485 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12161053 — Surrogate Endpoint (SUR): Blood pressure
Study 8567766 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 668773 — Surrogate Endpoint (SUR): Blood pressure
Study 15006188 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9819045 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30647912 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 10363570 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2127044 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 24329187 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8690115 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 7102534 — Surrogate Endpoint (SUR): Blood pressure
Study 24487616 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24487616 — Safety Biomarker (SAF): BDNF
Study 23046818 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23046818 — Surrogate Endpoint (SUR): Blood pressure
Study 3323261 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31242079 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 31242079 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27387325 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 1937843 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31867913 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31867913 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31867913 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26071192 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 23660099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2