TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04467203 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT04419402 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00863655 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01743911 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01743911 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00598910 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT04351503 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04479436 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT04479436 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03261284 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03154489 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT03154489 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT02247323 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT03887338 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03754179 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00445913 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT00445913 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT00445913 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study NCT01263197 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04036409 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03581279 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study NCT00856674 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT03288103 — Predictive Biomarker (PRD): Aggrecan core protein
Genes: ACAN; AGC1; CSPG1; MSK16
Study NCT00005442 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01774396 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02877992 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study NCT02877992 — Predictive Biomarker (PRD): TACR1 mRNA
Genes: TACR1; NK1R; TAC1R
Study NCT02877992 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TACR2 mRNA
Genes: TACR2; NK2R; NKNAR; TAC2R
Study NCT02877992 — Predictive Biomarker (PRD): TACR3 mRNA
Genes: TACR3; NK3R; TAC3R
Study NCT02877992 — Predictive Biomarker (PRD): KISS1 mRNA
Genes: KISS1; PP5098
Study NCT02877992 — Predictive Biomarker (PRD): KISS1R mRNA
Genes: KISS1R; AXOR12; GPR54
Study NCT02622126 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01454102 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01454102 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01378871 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00002558 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02036814 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01339143 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03033355 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03033355 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02132026 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01526304 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01271985 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00163176 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00042861 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study NCT02009904 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02668653 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00462995 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01440621 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01869595 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00722072 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02286947 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00491842 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01099176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01099176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04580979 — Predictive Biomarker (PRD): FDXR mRNA
Genes: FDXR; ADXR
Study NCT02215720 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01875094 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01093157 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00681642 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03577860 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT01061814 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01632566 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03847701 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study NCT00000874 — Predictive Biomarker (PRD): GART mRNA
Genes: GART; PGFT; PRGS
Study NCT03052075 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02395081 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01359670 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT02440282 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02642016 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT03262610 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02562677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study NCT04330404 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03585764 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT04659876 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04659876 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04659876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04659876 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT04388969 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT03056196 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03384862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00716651 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT00307749 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT02922062 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01851642 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT01745458 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT01851681 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT05569083 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03066245 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01140360 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT03266510 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00148317 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00001238 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT03373305 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT02249650 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study NCT02428634 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03820830 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03820830 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03820830 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03820830 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00080587 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT00398437 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01238926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01810393 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03449212 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03922009 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01868997 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study NCT04690764 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01252901 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT00877149 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03374670 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT01463956 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT03834181 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02086253 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT02086253 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT01807364 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04828629 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03403868 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04916873 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT03343899 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT04057118 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study NCT04382170 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00420446 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00770614 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04627402 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03569735 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01068847 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00860860 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02633150 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04575558 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00784914 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT00801177 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00801177 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01178060 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02102022 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT03430115 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00283114 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT00071071 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04815499 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT04537130 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04537130 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03173521 — Predictive Biomarker (PRD): ARSB mRNA
Genes: ARSB
Study NCT00076635 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01104935 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01104935 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01422655 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT01422655 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT03126188 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT03195699 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT02590588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02362958 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02938949 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02938949 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00426777 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00426777 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01696227 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00199563 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT00199563 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02092194 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01890616 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00940407 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02255136 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT02255136 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01249261 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03072056 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00206908 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00206908 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02559141 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01153932 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01274052 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03872479 — Predictive Biomarker (PRD): CEP290 mRNA
Genes: CEP290; BBS14; KIAA0373; NPHP6
Study NCT01768130 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT01602406 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01602406 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01211483 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03473496 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03473496 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT03473496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT04345744 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02057783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01452334 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01592357 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02725918 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04601961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04601961 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04601961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01327482 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT03469765 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT00128518 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04184700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04184700 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT04184700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT04149067 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01029366 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02930512 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00213772 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study NCT02858414 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02706860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02706860 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT03307889 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03428971 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study NCT01412476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01412476 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT02765516 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02699749 — Predictive Biomarker (PRD): CDC7 mRNA
Genes: CDC7; CDC7L1
Study NCT02172885 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04094272 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03825783 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study NCT03825783 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study NCT05022576 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03460249 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02421835 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03829306 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02255552 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01619514 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02280239 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04509921 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02157883 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02157883 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00669734 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01673542 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study NCT00422682 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT00796276 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT03393767 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02292186 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT00296621 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03085992 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01704599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01704599 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01704599 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02864290 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT04642339 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02479971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03757637 — Predictive Biomarker (PRD): RARB mRNA
Genes: RARB; HAP; NR1B2
Study NCT01104311 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04296370 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03195023 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03195023 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01545492 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03630315 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01954446 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01833143 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01886066 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT02331212 — Predictive Biomarker (PRD): HAS2 mRNA
Genes: HAS2
Study NCT02331212 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02069899 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03397407 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01957618 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04552743 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04192058 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT03868657 — Safety Biomarker (SAF): KCNH2
Genes: Kv11.1; HERG; erg1
Study NCT04675866 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT00384670 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03452657 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02809482 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study NCT03975582 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01747876 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02679833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT06223984 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study NCT06223984 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02882659 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study NCT03252080 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04453982 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02833688 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04418076 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00265239 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01737437 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01342211 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00431665 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01489189 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01489189 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00716755 — Safety Biomarker (SAF): DRD2
Study NCT02339883 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05403099 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01619501 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study NCT03604406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00720915 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer