TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16920503 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15309484 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7986856 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 23934169 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1962905 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 1962905 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 26302142 — Surrogate Endpoint (SUR): Blood pressure
Study 21406499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18192510 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10568568 — Predictive Biomarker (PRD): KY mRNA
Genes: KY
Study 7061569 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 23038750 — Surrogate Endpoint (SUR): Blood pressure
Study 9833596 — Surrogate Endpoint (SUR): Blood pressure
Study 30700356 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28493519 — Safety Biomarker (SAF): DRD2
Study 2859421 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24773760 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 22466942 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 2220647 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2220647 — Surrogate Endpoint (SUR): Blood pressure
Study 17377504 — Surrogate Endpoint (SUR): Serum creatinine
Study 30264293 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 30264293 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 25524478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25524478 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25524478 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 17577104 — Surrogate Endpoint (SUR): Blood pressure
Study 9115054 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26052959 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 26052959 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26052959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26052959 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 26052959 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 23952947 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23952947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23952947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23952947 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 1633702 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 6649755 — Surrogate Endpoint (SUR): Blood pressure
Study 26840505 — Safety Biomarker (SAF): Reactive oxygen species
Study 20212335 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 7775331 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1320279 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21784820 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21784820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21784820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15120711 — Surrogate Endpoint (SUR): Blood pressure
Study 11402826 — Surrogate Endpoint (SUR): Blood pressure
Study 4035650 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 16160598 — Surrogate Endpoint (SUR): Serum creatinine
Study 1704550 — Surrogate Endpoint (SUR): Blood pressure
Study 27207016 — Monitoring Biomarker (MOI): HBV DNA
Study 23450051 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 23450051 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23450051 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19475410 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 26711384 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 23275036 — Surrogate Endpoint (SUR): Blood pressure
Study 17851681 — Surrogate Endpoint (SUR): Blood pressure
Study 1911739 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26340264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26340264 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 26340264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26340264 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23657962 — Surrogate Endpoint (SUR): Blood pressure
Study 21418836 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 11256536 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8988997 — Surrogate Endpoint (SUR): Blood pressure
Study 20423998 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30524135 — Surrogate Endpoint (SUR): Blood pressure
Study 30633595 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23241943 — Predictive Biomarker (PRD): PDE4D mRNA
Genes: PDE4D; DPDE3
Study 23241943 — Predictive Biomarker (PRD): TJP1 mRNA
Genes: TJP1; ZO1
Study 23241943 — Predictive Biomarker (PRD): PPA2 mRNA
Genes: PPA2; HSPC124
Study 9106936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9106936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31343521 — Surrogate Endpoint (SUR): Blood pressure
Study 17268412 — Predictive Biomarker (PRD): BCAM mRNA
Genes: BCAM; LU; MSK19
Study 2090337 — Surrogate Endpoint (SUR): Blood pressure
Study 31318615 — Surrogate Endpoint (SUR): Blood pressure
Study 28639995 — Surrogate Endpoint (SUR): Bone mineral density
Study 16958130 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 9536878 — Surrogate Endpoint (SUR): Blood pressure
Study 26577258 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23739063 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23739063 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 23739063 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 23739063 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23739063 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 23739063 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 23739063 — Predictive Biomarker (PRD): AKT2 mRNA
Genes: AKT2
Study 23739063 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11008908 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1348010 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 1348010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 1348010 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29373274 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28701677 — Surrogate Endpoint (SUR): Serum creatinine
Study 25979186 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21958380 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 21958380 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6385278 — Surrogate Endpoint (SUR): Blood pressure
Study 24248037 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 18387167 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18387167 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21389909 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12920692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6357204 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18824917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18824917 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22318947 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 20558919 — Monitoring Biomarker (MOI): HBV DNA
Study 21418991 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 12110838 — Predictive Biomarker (PRD): VIT mRNA
Genes: VIT; UNQ647/PRO1277
Study 31755220 — Monitoring Biomarker (MOI): HBV DNA
Study 16015260 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 16015260 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 16015260 — Safety Biomarker (SAF): Reactive oxygen species
Study 30776296 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20608875 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16050428 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 16050428 — Surrogate Endpoint (SUR): Serum testosterone
Study 31717901 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 11778097 — Surrogate Endpoint (SUR): Blood pressure
Study 24832787 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 24832787 — Predictive Biomarker (PRD): Hormone receptor
Study 19781043 — Surrogate Endpoint (SUR): Blood pressure
Study 12692962 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 26887521 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26887521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21174145 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21174145 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21174145 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16970600 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 27538770 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 15763436 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7489845 — Surrogate Endpoint (SUR): Serum creatinine
Study 17849093 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15340127 — Surrogate Endpoint (SUR): Plasma methotrexate
Study 11595776 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29320589 — Safety Biomarker (SAF): Hyaluronic acid
Study 8879603 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8879603 — Surrogate Endpoint (SUR): Blood pressure
Study 23722951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15291291 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11159760 — Predictive Biomarker (PRD): NOCT mRNA
Genes: NOCT; CCR4; CCRN4L; NOC
Study 31861993 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 17093161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17093161 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17093161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8535199 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2691317 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 26955704 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22674544 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 16791109 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28634649 — Surrogate Endpoint (SUR): Serum calcium
Study 25439435 — Surrogate Endpoint (SUR): Blood pressure
Study 23972322 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 21225699 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 25106506 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 23137512 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11874394 — Surrogate Endpoint (SUR): Blood pressure
Study 31305505 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31305505 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30936690 — Surrogate Endpoint (SUR): Blood pressure
Study 25616431 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20001838 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17195236 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17195236 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12686786 — Surrogate Endpoint (SUR): Blood pressure
Study 10985616 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 22541754 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 6340700 — Surrogate Endpoint (SUR): Blood pressure
Study 22802432 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 10426160 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26356419 — Surrogate Endpoint (SUR): Blood pressure
Study 22235525 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 19516186 — Surrogate Endpoint (SUR): Blood pressure
Study 17410045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 3931467 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3931467 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30834441 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30834441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30834441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7759724 — Surrogate Endpoint (SUR): Blood pressure
Study 23840145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7677828 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 30918221 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8874906 — Surrogate Endpoint (SUR): Blood pressure
Study 16950290 — Predictive Biomarker (PRD): VIT mRNA
Genes: VIT; UNQ647/PRO1277
Study 9143608 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11251036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11251036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7516831 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9405729 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9405729 — Surrogate Endpoint (SUR): Serum calcium
Study 9405729 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 14522569 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 6085376 — Surrogate Endpoint (SUR): Blood pressure
Study 20811347 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3680599 — Surrogate Endpoint (SUR): Blood pressure
Study 16263834 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26917504 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 16052544 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 26721913 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16004813 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 16004813 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16004813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16004813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16004813 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 16004813 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16004813 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16004813 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22983593 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16944044 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25615959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25615959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21135170 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 17165637 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17165637 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17165637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12670129 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12670129 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3287943 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11876933 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9730797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9730797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9730797 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28284883 — Surrogate Endpoint (SUR): Blood pressure
Study 21077801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21077801 — Surrogate Endpoint (SUR): Bone mineral density
Study 7798535 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28774396 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11014375 — Surrogate Endpoint (SUR): Blood pressure
Study 26415549 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 22101166 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22101166 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 22101166 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 22101166 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 22101166 — Predictive Biomarker (PRD): GNAS-AS1
Study 17897821 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17897821 — Predictive Biomarker (PRD): Hormone receptor
Study 29930229 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 29930229 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 18238963 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18238963 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18238963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3904322 — Surrogate Endpoint (SUR): Blood pressure
Study 26038091 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 26038091 — Predictive Biomarker (PRD): ISM1 mRNA
Genes: ISM1; C20orf82; ISM
Study 24190613 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 22894176 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 16380486 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8824695 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3841005 — Safety Biomarker (SAF): DRD2
Study 3841005 — Surrogate Endpoint (SUR): Blood pressure
Study 21506242 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 17487211 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17487211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17487211 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9113631 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9113631 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8471596 — Safety Biomarker (SAF): XRCC1
Genes: RCC
Study 19840783 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19840783 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26574791 — Surrogate Endpoint (SUR): Bone mineral density
Study 19237683 — Surrogate Endpoint (SUR): Blood pressure
Study 19237683 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17573877 — Predictive Biomarker (PRD): TDO2 mRNA
Genes: TDO2; TDO
Study 12050245 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10220796 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10220796 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 2240638 — Surrogate Endpoint (SUR): Blood pressure
Study 26558428 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 14697944 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 14697944 — Surrogate Endpoint (SUR): Blood pressure
Study 6170414 — Predictive Biomarker (PRD): TG mRNA
Genes: TG