TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01268566 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01872845 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03648879 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT02744079 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT04415112 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02696941 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03242616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT05187858 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT05187858 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03544814 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03475134 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03475134 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT01443377 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02060097 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02940678 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04825145 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT01513356 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01513356 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02215798 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT01366807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03186937 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT03163628 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03163628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03163628 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT02049437 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03950908 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT00789061 — Predictive Biomarker (PRD): SLC26A4 mRNA
Genes: SLC26A4; PDS
Study NCT04591652 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01042535 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00645424 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00645424 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02450877 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT02450877 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study NCT02450877 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYH11 mRNA
Genes: MYH11; KIAA0866
Study NCT02450877 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02211014 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04158817 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04818996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04818996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00498238 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03811132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03811132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00666250 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02326974 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00966381 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00638794 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT01639950 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00962884 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02032355 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03866109 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03866109 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT02975037 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02125240 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03127345 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05004142 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03233074 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03125174 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study NCT01760902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01760902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02607813 — Predictive Biomarker (PRD): DUSP6 mRNA
Genes: DUSP6; MKP3; PYST1
Study NCT03868384 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04159675 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04159675 — Predictive Biomarker (PRD): DMP1 mRNA
Genes: DMP1
Study NCT04159675 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study NCT02667678 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT06628739 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT03164616 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03164616 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03164616 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00823654 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00823654 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00823654 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03736486 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03328728 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01518101 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03271606 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT00111358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00111358 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00111358 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00111358 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT01360827 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT00399737 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00399737 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03509662 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06178692 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT03609047 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01345318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04715776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00328016 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03805841 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03805841 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03805841 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study NCT02808988 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT01538836 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00227266 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT00227266 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00571389 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT04111588 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01373879 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study NCT01286558 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02519556 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT02519556 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02519556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04338529 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05039437 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03971578 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study NCT01587521 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00242385 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00002702 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02022696 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT02022696 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01723774 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01723774 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01723774 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00450983 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03427476 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04060511 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02946216 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02946216 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT02946216 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02946216 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01684878 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT03951519 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00168090 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00168090 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT01393730 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03810885 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03123783 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT00974064 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT05753280 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT04272151 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT02641002 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT02227459 — Predictive Biomarker (PRD): SERPINH1 mRNA
Genes: SERPINH1; CBP1; CBP2; HSP47; SERPINH2; PIG14
Study NCT01434576 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT03174938 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02774421 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02268253 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT02268253 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT01201759 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02558231 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02498275 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT00857259 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03393416 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02066337 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01640184 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT02515214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03353298 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01388543 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT04467463 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT00630864 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT04399265 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study NCT04213209 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT03921138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02470091 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT03572166 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01951690 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT01951690 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01951690 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT03966625 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study NCT02804217 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02316314 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT02600429 — Predictive Biomarker (PRD): RGN mRNA
Genes: RGN; SMP30
Study NCT04355949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02551393 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04351230 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01654276 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01654276 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT01886482 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03585907 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03585907 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02265341 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT02265341 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT02560428 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00698477 — Predictive Biomarker (PRD): RARB mRNA
Genes: RARB; HAP; NR1B2
Study NCT00698477 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study NCT00698477 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT05449093 — Safety Biomarker (SAF): Interleukin 1
Study NCT05612282 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study NCT04832048 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02323165 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00749502 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01631214 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03527251 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03401073 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT01464151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00450502 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT00706355 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT00072072 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00196599 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03653624 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02331693 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01610609 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04052971 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT03392740 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03392740 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01906229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01906229 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT06616428 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00051558 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01075048 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02223793 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01469260 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01195649 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05571267 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT05571267 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05571267 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01699529 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04161391 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT04161391 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT03417791 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02499224 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT00618293 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00997334 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00997334 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02974491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT02974491 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03940482 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03940482 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03293667 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04296058 — Predictive Biomarker (PRD): SOX4 mRNA
Genes: SOX4
Study NCT04296058 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT04486495 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT04357613 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04357613 — Predictive Biomarker (PRD): ABL2 mRNA
Genes: ABL2; ABLL; ARG
Study NCT03871868 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00248170 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02377921 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study NCT00488813 — Predictive Biomarker (PRD): MICU2 mRNA
Genes: MICU2; EFHA1
Study NCT04249674 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00266708 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03504449 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00013975 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05124015 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05124015 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00698659 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00698659 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01762488 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03809988 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03809988 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03809988 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02286596 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03830021 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04408183 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT04146831 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT02034695 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00987649 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT00987649 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT01235377 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04781114 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03347591 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT00754442 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study NCT03111095 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00150696 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02433119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01648283 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT04977661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04977661 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT00839124 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT00828620 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01429090 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01413048 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01906359 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03475628 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00396331 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00396331 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03580564 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study NCT02304315 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02675959 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34