TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17944770 — Surrogate Endpoint (SUR): Serum creatinine
Study 20031582 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 20031582 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 15316717 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 10190777 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27921185 — Surrogate Endpoint (SUR): Bone mineral density
Study 25818679 — Surrogate Endpoint (SUR): Blood pressure
Study 24212988 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 21357307 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31549208 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 30309244 — Predictive Biomarker (PRD): TPH2 mRNA
Genes: TPH2; NTPH
Study 30309244 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 30309244 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 30309244 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 22966986 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 21242462 — Surrogate Endpoint (SUR): Blood pressure
Study 19232762 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19232762 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29525345 — Surrogate Endpoint (SUR): Bacterial count
Study 12541152 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 10759650 — Surrogate Endpoint (SUR): Blood pressure
Study 1425528 — Surrogate Endpoint (SUR): Blood pressure
Study 26818586 — Predictive Biomarker (PRD): MKNK1 mRNA
Genes: MKNK1; MNK1
Study 26818586 — Predictive Biomarker (PRD): UBTF mRNA
Genes: UBTF; UBF; UBF1
Study 22072492 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 19880433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31125296 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 21621801 — Surrogate Endpoint (SUR): Blood pressure
Study 21621801 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18993147 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30587441 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30587441 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 26496309 — Monitoring Biomarker (MOI): Cell-free DNA
Study 26496309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2577711 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11327626 — Surrogate Endpoint (SUR): Blood pressure
Study 9594209 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 25465108 — Surrogate Endpoint (SUR): Blood pressure
Study 9457400 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21838411 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 21838411 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19289619 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11092994 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3533547 — Surrogate Endpoint (SUR): Blood pressure
Study 20814040 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9039930 — Surrogate Endpoint (SUR): Serum potassium
Study 2252531 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25781537 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 25781537 — Surrogate Endpoint (SUR): Blood pressure
Study 23348398 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 19567992 — Surrogate Endpoint (SUR): Bone mineral density
Study 15309461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7955265 — Safety Biomarker (SAF): Interleukin 1
Study 7955265 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29346507 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 25605643 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 14573335 — Surrogate Endpoint (SUR): Blood pressure
Study 9220210 — Surrogate Endpoint (SUR): Blood pressure
Study 9220210 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8148213 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31200560 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31200560 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28068001 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 25788001 — Surrogate Endpoint (SUR): Blood pressure
Study 20818901 — Surrogate Endpoint (SUR): Blood pressure
Study 17322430 — Surrogate Endpoint (SUR): Bone mineral density
Study 16353041 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 16353041 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16353041 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16353041 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1935475 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 1935475 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 7723338 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30102389 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30102389 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 21285125 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29096833 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 29096833 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29096833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23537979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10764680 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8453962 — Surrogate Endpoint (SUR): Blood pressure
Study 2429834 — Surrogate Endpoint (SUR): Blood pressure
Study 22876730 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12890374 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6682324 — Surrogate Endpoint (SUR): Blood pressure
Study 29924696 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 17437473 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 2534084 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26165955 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 16557155 — Surrogate Endpoint (SUR): Blood pressure
Study 11504315 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7700061 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22972879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22972879 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20601414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20601414 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10908771 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8720610 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 18516070 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 18516070 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 29985652 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20800241 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 20800241 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20800241 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20800241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1479106 — Surrogate Endpoint (SUR): Serum calcium
Study 6365838 — Surrogate Endpoint (SUR): Blood pressure
Study 20148772 — Surrogate Endpoint (SUR): Blood pressure
Study 26387692 — Surrogate Endpoint (SUR): Serum creatinine
Study 26387692 — Surrogate Endpoint (SUR): Bone mineral density
Study 10495686 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30639231 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30639231 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24622416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2563317 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2563317 — Surrogate Endpoint (SUR): Blood pressure
Study 25919636 — Surrogate Endpoint (SUR): Bone mineral density
Study 21771304 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 14982609 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11467760 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11467760 — Surrogate Endpoint (SUR): Blood pressure
Study 26380442 — Surrogate Endpoint (SUR): Blood pressure
Study 19060449 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19060449 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31147187 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31147187 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 16275368 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11271221 — Surrogate Endpoint (SUR): Blood pressure
Study 11271221 — Surrogate Endpoint (SUR): Serum creatinine
Study 24968970 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24002501 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24002501 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 24002501 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24002501 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8572782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8572782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8572782 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30098049 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 16117978 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 14685054 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14685054 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6613908 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6613908 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31663173 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 29912858 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 29912858 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27343175 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24365194 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15668427 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10950767 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1477491 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 17696277 — Surrogate Endpoint (SUR): Blood pressure
Study 17696277 — Surrogate Endpoint (SUR): Serum creatinine
Study 16181540 — Surrogate Endpoint (SUR): Blood pressure
Study 12057714 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10816058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12927929 — Predictive Biomarker (PRD): EIF2AK2 mRNA
Genes: EIF2AK2; PKR; PRKR
Study 10773790 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 9326983 — Surrogate Endpoint (SUR): Blood pressure
Study 12393528 — Predictive Biomarker (PRD): Liver iron
Study 27075216 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 27075216 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 17898099 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10155673 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 31814226 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 10784360 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 1833529 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28956671 — Surrogate Endpoint (SUR): Blood pressure
Study 28956671 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24233571 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10199771 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 29535139 — Surrogate Endpoint (SUR): Serum creatinine
Study 8750405 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8750405 — Surrogate Endpoint (SUR): Blood pressure
Study 25835119 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25835119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25835119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25835119 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25835119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24302596 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 22357746 — Surrogate Endpoint (SUR): Blood pressure
Study 21205122 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22735306 — Surrogate Endpoint (SUR): Serum creatinine
Study 20847403 — Safety Biomarker (SAF): BDNF
Study 25037746 — Surrogate Endpoint (SUR): Blood pressure
Study 18394446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18394446 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 31101617 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22459616 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11524058 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11524058 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8313933 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 3791867 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27447483 — Predictive Biomarker (PRD): PNN mRNA
Genes: PNN; DRS; MEMA
Study 24722495 — Surrogate Endpoint (SUR): Blood pressure
Study 20978144 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9834039 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2679473 — Surrogate Endpoint (SUR): Blood pressure
Study 25934525 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24204757 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 15486607 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 14760258 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27484356 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 26216729 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 16894312 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 14680093 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8977677 — Surrogate Endpoint (SUR): Serum calcium
Study 8977677 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 6530546 — Surrogate Endpoint (SUR): Blood pressure
Study 26806217 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 19084683 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17942835 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16187176 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 16187176 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16187176 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12537187 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 12537187 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31881986 — Surrogate Endpoint (SUR): Blood pressure
Study 31355514 — Safety Biomarker (SAF): Interleukin 12
Study 31355514 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24506405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 13678870 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10809018 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1900443 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 25738784 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 9049526 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9049526 — Surrogate Endpoint (SUR): Blood pressure
Study 28253390 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28253390 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28253390 — Predictive Biomarker (PRD): Hormone receptor
Study 25338110 — Surrogate Endpoint (SUR): Bone mineral density
Study 24482090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17300593 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15215794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15215794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15215794 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11149474 — Surrogate Endpoint (SUR): Bone mineral density
Study 11149474 — Surrogate Endpoint (SUR): Serum calcium
Study 11149474 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30797222 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 23282858 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17304146 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 12960682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8789548 — Safety Biomarker (SAF): Hyaluronic acid
Study 23999998 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18448569 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18448569 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11002232 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 11002232 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8623886 — Surrogate Endpoint (SUR): Blood pressure
Study 31593830 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 20485203 — Surrogate Endpoint (SUR): Bone mineral density
Study 7590814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7590814 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7590814 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28796276 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28796276 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23146660 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 18505668 — Surrogate Endpoint (SUR): Serum creatinine
Study 25971920 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25971920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24224515 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24224515 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 9192123 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17875819 — Surrogate Endpoint (SUR): Blood pressure
Study 15468362 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 11301566 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31826241 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 31826241 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study 31826241 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28379519 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15947624 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 8877673 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8877673 — Surrogate Endpoint (SUR): Blood pressure
Study 30995665 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 24185114 — Safety Biomarker (SAF): Hyaluronic acid
Study 20052358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20052358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16221568 — Surrogate Endpoint (SUR): Blood pressure
Study 8682929 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26153159 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23522341 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18656274 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17330512 — Surrogate Endpoint (SUR): Blood pressure
Study 17330512 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11112128 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11112128 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 27400997 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27400997 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein