TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16110714 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 26226215 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 2105256 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18414765 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 14582612 — Surrogate Endpoint (SUR): Blood pressure
Study 27102223 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 18640464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18640464 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18640464 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12537676 — Surrogate Endpoint (SUR): Blood pressure
Study 9825270 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 24075779 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24075779 — Predictive Biomarker (PRD): GRB7 mRNA
Genes: GRB7
Study 24075779 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 24075779 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 24075779 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 22134468 — Surrogate Endpoint (SUR): Blood pressure
Study 19101266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19101266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19101266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12135137 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12135137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 12135137 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9825188 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9825188 — Surrogate Endpoint (SUR): Blood pressure
Study 28374097 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 2760908 — Surrogate Endpoint (SUR): Blood pressure
Study 28536825 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 17848651 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8470032 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 1348481 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18797149 — Safety Biomarker (SAF): Reactive oxygen species
Study 11271081 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2368376 — Surrogate Endpoint (SUR): Blood pressure
Study 29788823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23734252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19937457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15920347 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 1839993 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17312215 — Surrogate Endpoint (SUR): Blood pressure
Study 7977115 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9260008 — Surrogate Endpoint (SUR): Blood pressure
Study 27643171 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 27643171 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27643171 — Surrogate Endpoint (SUR): Blood pressure
Study 20664293 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 15757965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15757965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30665323 — Surrogate Endpoint (SUR): Bone mineral density
Study 12784089 — Surrogate Endpoint (SUR): Bone mineral density
Study 10532516 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10532516 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8682483 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24380796 — Surrogate Endpoint (SUR): Blood pressure
Study 17159193 — Surrogate Endpoint (SUR): Bone mineral density
Study 15901026 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15901026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11953965 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 9857661 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2172175 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 2172175 — Surrogate Endpoint (SUR): Blood pressure
Study 18996881 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18996881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22090477 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 8160944 — Surrogate Endpoint (SUR): Serum creatinine
Study 31130268 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 27794124 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26343814 — Surrogate Endpoint (SUR): Blood pressure
Study 19255824 — Surrogate Endpoint (SUR): Blood pressure
Study 16421661 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16421661 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16421661 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15614033 — Surrogate Endpoint (SUR): Blood pressure
Study 21813076 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21813076 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17665078 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17665078 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 11166779 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31126103 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31126103 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29058153 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 30621298 — Safety Biomarker (SAF): Reactive oxygen species
Study 19464028 — Surrogate Endpoint (SUR): Serum potassium
Study 12105816 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12105816 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 23499806 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21163569 — Predictive Biomarker (PRD): SLC11A1 mRNA
Genes: SLC11A1; LSH; NRAMP; NRAMP1
Study 16595318 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 10898445 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3921518 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31305131 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31305131 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29477448 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 29477448 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27438317 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27438317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24283388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21899713 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 28643661 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 19139780 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11303205 — Surrogate Endpoint (SUR): Blood pressure
Study 12641480 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12641480 — Surrogate Endpoint (SUR): Blood pressure
Study 28368936 — Surrogate Endpoint (SUR): Blood pressure
Study 11509481 — Surrogate Endpoint (SUR): Blood pressure
Study 3523395 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 26108136 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 17456569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17456569 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17456569 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 14735126 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 30758417 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30758417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17605959 — Surrogate Endpoint (SUR): Blood pressure
Study 15292331 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15292331 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8130050 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26076828 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26076828 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19329498 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 19205663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23197250 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18075220 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16545905 — Safety Biomarker (SAF): MTHFR
Study 3912618 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 26253006 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23033241 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12576886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12576886 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 12576886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12576886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12576886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12576886 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 10588995 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1963650 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8100105 — Surrogate Endpoint (SUR): Blood pressure
Study 29313753 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29313753 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 27110573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24065043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31713863 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23905837 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23905837 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22015710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12476528 — Safety Biomarker (SAF): Hyaluronic acid
Study 18942246 — Surrogate Endpoint (SUR): Blood pressure
Study 1971027 — Surrogate Endpoint (SUR): Blood pressure
Study 17300592 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15240537 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15240537 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15240537 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2427301 — Surrogate Endpoint (SUR): Blood pressure
Study 10071299 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 10071299 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 23807094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21155632 — Surrogate Endpoint (SUR): Blood pressure
Study 30593463 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 26401255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26401255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26401255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23467813 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 23467813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20970351 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9564119 — Predictive Biomarker (PRD): TRO mRNA
Genes: TRO; KIAA1114; MAGED3
Study 2721537 — Surrogate Endpoint (SUR): Blood pressure
Study 11339099 — Surrogate Endpoint (SUR): Bone mineral density
Study 9549925 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9928754 — Surrogate Endpoint (SUR): Blood pressure
Study 2125646 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2125646 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 7471064 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20404379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20404379 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6463391 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29716940 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29716940 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29716940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20075335 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study 17765133 — Surrogate Endpoint (SUR): Blood pressure
Study 15673327 — Surrogate Endpoint (SUR): Serum calcium
Study 29145211 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17400086 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 22161728 — Surrogate Endpoint (SUR): Bone mineral density
Study 22161728 — Surrogate Endpoint (SUR): New morphometric vertebral fractures
Study 22161728 — Surrogate Endpoint (SUR): Serum creatinine
Study 19786251 — Surrogate Endpoint (SUR): Blood pressure
Study 15911864 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 3388475 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 350251 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 15713727 — Surrogate Endpoint (SUR): Serum testosterone
Study 31336497 — Surrogate Endpoint (SUR): Blood pressure
Study 25459687 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25459687 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25617561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25617561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22137672 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22137672 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 22137672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28658164 — Surrogate Endpoint (SUR): Blood pressure
Study 12864878 — Surrogate Endpoint (SUR): Blood pressure
Study 12864878 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8165074 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18272959 — Surrogate Endpoint (SUR): Blood pressure
Study 1851785 — Surrogate Endpoint (SUR): Blood pressure
Study 1851785 — Surrogate Endpoint (SUR): Serum creatinine
Study 1851785 — Surrogate Endpoint (SUR): Serum potassium
Study 1851785 — Surrogate Endpoint (SUR): Serum uric acid
Study 7226124 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 30646884 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 22240754 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26481226 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24574085 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 20425759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20425759 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20425759 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7614898 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28668386 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study 16352815 — Predictive Biomarker (PRD): Liver iron
Study 15285851 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20605872 — Surrogate Endpoint (SUR): Bone mineral density
Study 7595101 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 7595101 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1850942 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17006667 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 17006667 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 15567189 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 15567189 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 24920046 — Surrogate Endpoint (SUR): Blood pressure
Study 6504708 — Surrogate Endpoint (SUR): Serum uric acid
Study 29511971 — Surrogate Endpoint (SUR): Blood pressure
Study 20642481 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31307527 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 31307527 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 31307527 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 31307527 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31307527 — Surrogate Endpoint (SUR): Blood pressure
Study 22013952 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 18818699 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 15228864 — Surrogate Endpoint (SUR): Blood pressure
Study 9832299 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2553425 — Surrogate Endpoint (SUR): Blood pressure
Study 19580019 — Surrogate Endpoint (SUR): Blood pressure
Study 14994690 — Surrogate Endpoint (SUR): Blood pressure
Study 11320899 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9129083 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 30838389 — Surrogate Endpoint (SUR): Blood pressure
Study 16318774 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8592593 — Surrogate Endpoint (SUR): Blood pressure
Study 31483963 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17595888 — Predictive Biomarker (PRD): RNF2 mRNA
Genes: RNF2; BAP1; DING; HIPI3; RING1B
Study 10678541 — Surrogate Endpoint (SUR): Blood pressure
Study 10678541 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9164806 — Surrogate Endpoint (SUR): Blood pressure
Study 30103509 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7600120 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7600120 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9480238 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9480238 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7894531 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 7894531 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30639252 — Surrogate Endpoint (SUR): Blood pressure
Study 30639252 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22113536 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 22113536 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 17092241 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 17092241 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15243302 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 11341175 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 8861797 — Surrogate Endpoint (SUR): Serum creatinine
Study 24053577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24053577 — Surrogate Endpoint (SUR): Blood pressure
Study 11755289 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30666100 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 19405831 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 4082084 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 29846607 — Predictive Biomarker (PRD): BMAL1 mRNA
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 29846607 — Predictive Biomarker (PRD): AANAT mRNA
Genes: AANAT; SNAT