TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22865603 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 22865603 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22865603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14602215 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10912657 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30790160 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25083614 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17077928 — Surrogate Endpoint (SUR): Blood pressure
Study 9186381 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 3880687 — Surrogate Endpoint (SUR): Blood pressure
Study 30209858 — Predictive Biomarker (PRD): ADH1B mRNA
Genes: ADH1B; ADH2
Study 25644856 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31319234 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15326084 — Surrogate Endpoint (SUR): Blood pressure
Study 31773165 — Predictive Biomarker (PRD): A2M mRNA
Genes: A2M; CPAMD5; FWP007
Study 25823768 — Predictive Biomarker (PRD): TYRO3 mRNA
Genes: TYRO3; BYK; DTK; RSE; SKY; TIF
Study 16625008 — Surrogate Endpoint (SUR): Blood pressure
Study 7959537 — Surrogate Endpoint (SUR): Blood pressure
Study 23897949 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6704647 — Surrogate Endpoint (SUR): Blood pressure
Study 30364933 — Predictive Biomarker (PRD): POU4F1 mRNA
Genes: POU4F1; BRN3A; RDC1
Study 30364933 — Predictive Biomarker (PRD): MCM2 mRNA
Genes: MCM2; BM28; CCNL1; CDCL1; KIAA0030
Study 30364933 — Predictive Biomarker (PRD): SMC1B mRNA
Genes: SMC1B; SMC1L2
Study 30364933 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL6 mRNA
Genes: CXCL6; GCP2; SCYB6
Study 30364933 — Predictive Biomarker (PRD): MMP12 mRNA
Genes: MMP12; HME
Study 30364933 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17095559 — Surrogate Endpoint (SUR): Serum testosterone
Study 2782273 — Surrogate Endpoint (SUR): Blood pressure
Study 786662 — Surrogate Endpoint (SUR): Blood pressure
Study 15464333 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 15464333 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 2690225 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2690225 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17923591 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17923591 — Surrogate Endpoint (SUR): Serum creatinine
Study 17923591 — Surrogate Endpoint (SUR): Serum potassium
Study 2109531 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7324924 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30312135 — Surrogate Endpoint (SUR): Blood pressure
Study 24112444 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 24112444 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21857901 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29249774 — Surrogate Endpoint (SUR): Blood pressure
Study 19094535 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 25707 — Surrogate Endpoint (SUR): Blood pressure
Study 25707 — Surrogate Endpoint (SUR): Serum potassium
Study 24599421 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23363992 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9551752 — Surrogate Endpoint (SUR): Blood pressure
Study 7528129 — Surrogate Endpoint (SUR): Blood pressure
Study 30100558 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 18256071 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12195132 — Surrogate Endpoint (SUR): Blood pressure
Study 12195132 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29565951 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29565951 — Surrogate Endpoint (SUR): Blood pressure
Study 27436880 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22776095 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 22776095 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 16467067 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9814471 — Surrogate Endpoint (SUR): Serum creatinine
Study 24342715 — Surrogate Endpoint (SUR): Blood pressure
Study 17147835 — Surrogate Endpoint (SUR): Blood pressure
Study 7706571 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 16159735 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 8673775 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 1438624 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 21393578 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 21393578 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 18339032 — Safety Biomarker (SAF): Reactive oxygen species
Study 10873072 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31550800 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27817128 — Surrogate Endpoint (SUR): Blood pressure
Study 10080457 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1310566 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20456060 — Surrogate Endpoint (SUR): Blood pressure
Study 27009433 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 27009433 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 27009433 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 27009433 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 27009433 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11207642 — Surrogate Endpoint (SUR): Blood pressure
Study 21506190 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 26853601 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26853601 — Safety Biomarker (SAF): Reactive oxygen species
Study 26853601 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26486824 — Surrogate Endpoint (SUR): Serum testosterone
Study 11319675 — Surrogate Endpoint (SUR): Blood pressure
Study 7943771 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7943771 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7943771 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 7943771 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 7943771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7943771 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 7943771 — Safety Biomarker (SAF): Interleukin 1
Study 7943771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31826232 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31826232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31504126 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31504126 — Predictive Biomarker (PRD): HOXB13 mRNA
Genes: HOXB13
Study 31504126 — Predictive Biomarker (PRD): IL17RB mRNA
Genes: IL17RB; CRL4; EVI27; IL17BR; UNQ2501/PRO19612
Study 31504126 — Predictive Biomarker (PRD): Hormone receptor
Study 31504126 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11967798 — Surrogate Endpoint (SUR): Blood pressure
Study 24906822 — Surrogate Endpoint (SUR): Blood pressure
Study 22513516 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8134718 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3306546 — Surrogate Endpoint (SUR): Blood pressure
Study 28177703 — Predictive Biomarker (PRD): MLEC mRNA
Genes: MLEC; KIAA0152
Study 26211765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26211765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26211765 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10954004 — Surrogate Endpoint (SUR): Blood pressure
Study 10954004 — Surrogate Endpoint (SUR): Serum creatinine
Study 8660034 — Surrogate Endpoint (SUR): Blood pressure
Study 24694335 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 24694335 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study 24694335 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study 24694335 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 24694335 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 24694335 — Predictive Biomarker (PRD): TYRP1 mRNA
Genes: TYRP1; CAS2; TYRP; TYRRP
Study 24694335 — Predictive Biomarker (PRD): MCM6 mRNA
Genes: MCM6
Study 24694335 — Predictive Biomarker (PRD): HERC2 mRNA
Genes: HERC2
Study 23341518 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23341518 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20595800 — Surrogate Endpoint (SUR): Blood pressure
Study 8959150 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 4064565 — Surrogate Endpoint (SUR): Blood pressure
Study 24604409 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15954952 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25122437 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25122437 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30998689 — Predictive Biomarker (PRD): CASZ1 mRNA
Genes: CASZ1; CST; SRG; ZNF693
Study 30998689 — Predictive Biomarker (PRD): PPP3R1 mRNA
Genes: PPP3R1; CNA2; CNB
Study 30998689 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 30998689 — Predictive Biomarker (PRD): STIM2 mRNA
Genes: STIM2; KIAA1482
Study 30998689 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 30998689 — Predictive Biomarker (PRD): GATA2 mRNA
Genes: GATA2
Study 30998689 — Predictive Biomarker (PRD): NFATC2 mRNA
Genes: NFATC2; NFAT1; NFATP
Study 30998689 — Predictive Biomarker (PRD): SOX9 mRNA
Genes: SOX9
Study 30998689 — Predictive Biomarker (PRD): MICB mRNA
Genes: MICB; PERB11.2
Study 30998689 — Predictive Biomarker (PRD): CD209 mRNA
Genes: CD209; CLEC4L
Study 6499702 — Surrogate Endpoint (SUR): Blood pressure
Study 20021517 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 8562399 — Predictive Biomarker (PRD): POU2F3 mRNA
Genes: POU2F3; OTF11; PLA1
Study 30862658 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28098097 — Surrogate Endpoint (SUR): Serum creatinine
Study 28098097 — Safety Biomarker (SAF): Urinary total protein
Study 26148204 — Predictive Biomarker (PRD): ABCC4 mRNA
Genes: ABCC4; MOATB; MRP4
Study 26148204 — Predictive Biomarker (PRD): CLDN10 mRNA
Genes: CLDN10
Study 26148204 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 16179209 — Surrogate Endpoint (SUR): Bone mineral density
Study 2309991 — Surrogate Endpoint (SUR): Blood pressure
Study 31910030 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 12669742 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2132640 — Surrogate Endpoint (SUR): Blood pressure
Study 443256 — Surrogate Endpoint (SUR): Serum sodium
Study 443256 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25729933 — Surrogate Endpoint (SUR): Serum creatinine
Study 23940710 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 15937757 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 28698692 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25327485 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24502072 — Surrogate Endpoint (SUR): Blood pressure
Study 21986123 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29280043 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29145824 — Surrogate Endpoint (SUR): Blood pressure
Study 23542954 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 23542954 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 9225527 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 8356591 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30304749 — Surrogate Endpoint (SUR): Blood pressure
Study 18987098 — Surrogate Endpoint (SUR): Serum creatinine
Study 30979507 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 23211012 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10150222 — Surrogate Endpoint (SUR): Blood pressure
Study 23739650 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20418097 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 20418097 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20418097 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20418097 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 20418097 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 16860921 — Surrogate Endpoint (SUR): Blood pressure
Study 11864867 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 11864867 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8886295 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31094225 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 31094225 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 14710214 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 3936558 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 30107003 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 30107003 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study 21940766 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21940766 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12618584 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 12618584 — Surrogate Endpoint (SUR): Bone mineral density
Study 1343111 — Surrogate Endpoint (SUR): Blood pressure
Study 29587662 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 20737166 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16122072 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12100150 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12100150 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27716673 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 24030420 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9075142 — Surrogate Endpoint (SUR): Bone mineral density
Study 23690533 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23690533 — Surrogate Endpoint (SUR): Serum creatinine
Study 23690533 — Safety Biomarker (SAF): Urinary microalbumin
Study 23690533 — Surrogate Endpoint (SUR): Blood pressure
Study 15533351 — Surrogate Endpoint (SUR): Bone mineral density
Study 29455298 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14685445 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11061985 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9490579 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3927690 — Surrogate Endpoint (SUR): Blood pressure
Study 30345884 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30345884 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 27003517 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27003517 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27003517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27003517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27003517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24461901 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 17272671 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9767255 — Safety Biomarker (SAF): Reactive oxygen species
Study 24548447 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 20577103 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 18440181 — Surrogate Endpoint (SUR): Blood pressure
Study 18440181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6182412 — Surrogate Endpoint (SUR): Blood pressure
Study 8042821 — Surrogate Endpoint (SUR): Serum creatinine
Study 8042821 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17174637 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15955130 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15955130 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6932209 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 27919609 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 25676084 — Surrogate Endpoint (SUR): Blood pressure
Study 23591401 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 2889416 — Surrogate Endpoint (SUR): Blood pressure
Study 29137091 — Surrogate Endpoint (SUR): Blood pressure
Study 15151265 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7698722 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20632667 — Surrogate Endpoint (SUR): Blood pressure
Study 10804023 — Surrogate Endpoint (SUR): Serum calcium
Study 1737453 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29302609 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 11751716 — Surrogate Endpoint (SUR): Blood pressure
Study 30183438 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 15201246 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10914827 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 20053950 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 29355092 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26955678 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 22267464 — Monitoring Biomarker (MOI): HBV DNA
Study 11772264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2540757 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20177420 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 20177420 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 20177420 — Safety Biomarker (SAF): MTHFR
Study 15580170 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 27662296 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12968233 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 12968233 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12968233 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 30995657 — Surrogate Endpoint (SUR): Blood pressure
Study 30995657 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19536092 — Predictive Biomarker (PRD): ERCC5 mRNA
Genes: ERCC5; ERCM2; XPG; XPGC
Study 17825709 — Surrogate Endpoint (SUR): Serum creatinine
Study 1778353 — Surrogate Endpoint (SUR): Blood pressure
Study 1778353 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10080677 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2833577 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 29169967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29169967 — Surrogate Endpoint (SUR): Blood pressure
Study 18942124 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15824216 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 8923161 — Surrogate Endpoint (SUR): Blood pressure
Study 1352949 — Surrogate Endpoint (SUR): Blood pressure
Study 22759797 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20082236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16234514 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16234514 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 2191587 — Surrogate Endpoint (SUR): Blood pressure
Study 2191587 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19304990 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29096069 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 29096069 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26323598 — Predictive Biomarker (PRD): OGFRL1 mRNA
Genes: OGFRL1
Study 24705232 — Surrogate Endpoint (SUR): Blood pressure
Study 18039674 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 18039674 — Surrogate Endpoint (SUR): Blood pressure
Study 17209507 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8858057 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 31827687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31827687 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 31827687 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31827687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31827687 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28626088 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28626088 — Surrogate Endpoint (SUR): Blood pressure
Study 28626088 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1