TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00003861 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03242915 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04311697 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT03709381 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03709381 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00893997 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03455010 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT03737708 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study NCT06350461 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02663557 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04020848 — Predictive Biomarker (PRD): ATP1A3 mRNA
Genes: ATP1A3
Study NCT03313401 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03313401 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT03313401 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT02771509 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study NCT05458973 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00244660 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02161575 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02161575 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04420611 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT00196638 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03138096 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT00113230 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02023723 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02023723 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03515681 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01950325 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01950325 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03746249 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01638572 — Predictive Biomarker (PRD): B4GALNT3 mRNA
Genes: B4GALNT3
Study NCT02221453 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02221453 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03827824 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02648477 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02648477 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02648477 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01515137 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01538290 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00332254 — Safety Biomarker (SAF): Interleukin 1
Study NCT05679336 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study NCT05679336 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04274894 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04274894 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02398708 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02390479 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT01041807 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01247415 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02433197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02705807 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03118024 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03523728 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT04451616 — Predictive Biomarker (PRD): TAFA5 mRNA
Genes: TAFA5; FAM19A5; UNQ5208/PRO34524
Study NCT04874701 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01059240 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT03719703 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04521023 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02507700 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT00593944 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04267536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02038166 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00503035 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study NCT00503035 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT04417192 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT02371239 — Predictive Biomarker (PRD): LIPA mRNA
Genes: LIPA
Study NCT03070327 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT01306799 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02801838 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study NCT00527436 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04529681 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04515225 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02306109 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03076502 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04470830 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04470830 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03162276 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03162276 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03234699 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03234699 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT03234699 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03234699 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01552590 — Surrogate Endpoint (SUR): Serum sodium
Study NCT00734630 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02061566 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT02061566 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00006089 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03725436 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT03725436 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01415011 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01415011 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03453528 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00870220 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00774280 — Predictive Biomarker (PRD): RARS1 mRNA
Genes: RARS1; RARS
Study NCT02751879 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01922076 — Pharmacodynamic Biomarker (PDY): Cyclin-dependent kinase 1
Genes: CDK1; CDC2; CDC28A; CDKN1; P34CDC2
Study NCT00993642 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00993642 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study NCT02944682 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02355366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02408705 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00630123 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00630123 — Safety Biomarker (SAF): BDNF
Study NCT03040791 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03040791 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03040791 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03040791 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study NCT01434420 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01434420 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT01434420 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT01434420 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02658734 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03204188 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT03204188 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study NCT03204188 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT02728583 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02728583 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02728583 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03887533 — Predictive Biomarker (PRD): NPC1 mRNA
Genes: NPC1
Study NCT02709694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01858532 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00333671 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01881178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02900729 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03680924 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT00282906 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT03676296 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02649582 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT00181168 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00138658 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT00503165 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study NCT04883320 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02181816 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00631514 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04642027 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02759614 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03117751 — Predictive Biomarker (PRD): CEP72 mRNA
Genes: CEP72; KIAA1519
Study NCT03117751 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03117751 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03117751 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study NCT03117751 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT03117751 — Predictive Biomarker (PRD): MEF2D mRNA
Genes: MEF2D
Study NCT03117751 — Predictive Biomarker (PRD): TCF3 mRNA
Genes: TCF3; BHLHB21; E2A; ITF1
Study NCT03117751 — Predictive Biomarker (PRD): HLF mRNA
Genes: HLF
Study NCT03117751 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT03117751 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT03117751 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01612468 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02298894 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00922480 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01687179 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT02302352 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02230228 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02414165 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT02913872 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03044938 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02036411 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00050648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00023959 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02257138 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT02806089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02806089 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00207038 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study NCT02613884 — Surrogate Endpoint (SUR): Serum calcium
Study NCT03284515 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT02429726 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00829179 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01440270 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01440270 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00341159 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00341159 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT01547585 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01547585 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03911882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00896038 — Predictive Biomarker (PRD): TACR1 mRNA
Genes: TACR1; NK1R; TAC1R
Study NCT02518997 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01329679 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02512809 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00382590 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT01122407 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03381768 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01018628 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT02535884 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT02695992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05069506 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04173689 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT04452474 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00585000 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT02554903 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02554903 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01286194 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT03576131 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study NCT03079791 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study NCT01519908 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03611868 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT03611868 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT05395611 — Predictive Biomarker (PRD): EBP mRNA
Genes: EBP
Study NCT05395611 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT04259879 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study NCT01342484 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04430842 — Predictive Biomarker (PRD): SLC7A5 mRNA
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study NCT01733979 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00923403 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04825795 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05798676 — Predictive Biomarker (PRD): LEAP2 mRNA
Genes: LEAP2
Study NCT03998111 — Predictive Biomarker (PRD): CLTCL1 mRNA
Genes: CLTCL1; CLH22; CLTCL; CLTD
Study NCT03998111 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study NCT01046721 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00802204 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT04238910 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study NCT00396201 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00396201 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04515914 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study NCT02215551 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study NCT02055651 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01561014 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03335163 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT00847145 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study NCT01440959 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01440959 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01440959 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study NCT01440959 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02609932 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00908791 — Predictive Biomarker (PRD): THRSP mRNA
Genes: THRSP
Study NCT00908791 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study NCT00908791 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT00908791 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT01144988 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01144988 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01144988 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01679067 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03663465 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02689440 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02689440 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03743103 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00063141 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00063141 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03267316 — Predictive Biomarker (PRD): IL1RAP mRNA
Genes: IL1RAP; C3orf13; IL1R3
Study NCT00096785 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03969303 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03982836 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT00878566 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02187172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02187172 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02177396 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01578018 — Predictive Biomarker (PRD): DCLK1 mRNA
Genes: DCLK1; DCAMKL1; DCDC3A; KIAA0369
Study NCT01248169 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04476862 — Predictive Biomarker (PRD): Tripeptidyl-peptidase I
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study NCT03627416 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study NCT02737072 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT00296192 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01345136 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT03593850 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00562874 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00562874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01394120 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03384784 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT00415857 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01380730 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00871052 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00202878 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01867294 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01867294 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00661960 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01978782 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00105716 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03350529 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT02554331 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT01169675 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01169675 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04457505 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04457505 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT01111357 — Predictive Biomarker (PRD): PTPN22 mRNA
Genes: PTPN22; PTPN8
Study NCT01111357 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B