TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9843861 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31285784 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 31285784 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31285784 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31285784 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15523557 — Predictive Biomarker (PRD): APOBEC3C mRNA
Genes: APOBEC3C; APOBEC1L; PBI
Study 28540538 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 31050279 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 10688417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10688417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23870813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21757823 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21757823 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 21757823 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 17554248 — Surrogate Endpoint (SUR): Blood pressure
Study 17554248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31383853 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 28626220 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 27433865 — Surrogate Endpoint (SUR): Blood pressure
Study 11990913 — Surrogate Endpoint (SUR): Blood pressure
Study 9641187 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2929483 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29944915 — Predictive Biomarker (PRD): SLC25A3 mRNA
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 27121777 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9301385 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9301385 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31430058 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 21824454 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 8627841 — Surrogate Endpoint (SUR): Sperm parameters
Study 28394361 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28394361 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19222109 — Surrogate Endpoint (SUR): Serum creatinine
Study 14723265 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 8694204 — Surrogate Endpoint (SUR): Blood pressure
Study 25414155 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 25414155 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25414155 — Surrogate Endpoint (SUR): Blood pressure
Study 9424967 — Surrogate Endpoint (SUR): Blood pressure
Study 26504153 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 26504153 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22808955 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15743422 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 10820349 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25631224 — Surrogate Endpoint (SUR): Blood pressure
Study 25631224 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 16634995 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16634995 — Surrogate Endpoint (SUR): Blood pressure
Study 22554359 — Surrogate Endpoint (SUR): Blood pressure
Study 20602884 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20602884 — Surrogate Endpoint (SUR): Blood pressure
Study 7669308 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 30567604 — Surrogate Endpoint (SUR): Blood pressure
Study 25211927 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12198700 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 8583783 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2197347 — Surrogate Endpoint (SUR): Serum creatinine
Study 2197347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 510213 — Surrogate Endpoint (SUR): Blood pressure
Study 14981605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14981605 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7920609 — Surrogate Endpoint (SUR): Serum creatinine
Study 3279351 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 17690922 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7851275 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30316113 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 18095148 — Surrogate Endpoint (SUR): Blood pressure
Study 7859638 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 7859638 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 25624430 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25624430 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 16873908 — Surrogate Endpoint (SUR): Blood pressure
Study 3122247 — Surrogate Endpoint (SUR): Blood pressure
Study 27501767 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24477043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23121374 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15041587 — Surrogate Endpoint (SUR): Blood pressure
Study 9428917 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23135654 — Safety Biomarker (SAF): Hyaluronic acid
Study 9030968 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 28197932 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 28197932 — Predictive Biomarker (PRD): Hormone receptor
Study 18047523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10848924 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12451319 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12451319 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25499095 — Surrogate Endpoint (SUR): Serum calcium
Study 25499095 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15196263 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 15196263 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 15196263 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15196263 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 15196263 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 15196263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15196263 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 15196263 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 23211358 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 18301342 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 14756233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9035450 — Surrogate Endpoint (SUR): Blood pressure
Study 1494509 — Surrogate Endpoint (SUR): Blood pressure
Study 3887883 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8993854 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21932036 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21932036 — Pharmacodynamic Biomarker (PDY): DNA topoisomerase I
Genes: TOP1
Study 28236262 — Surrogate Endpoint (SUR): Blood pressure
Study 26220533 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22015077 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16305290 — Surrogate Endpoint (SUR): Blood pressure
Study 12001541 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9459074 — Surrogate Endpoint (SUR): Blood pressure
Study 7534217 — Surrogate Endpoint (SUR): Blood pressure
Study 23504241 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23504241 — Surrogate Endpoint (SUR): Blood pressure
Study 15482068 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 8167653 — Surrogate Endpoint (SUR): Serum potassium
Study 2850604 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19335435 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 14672612 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14672612 — Surrogate Endpoint (SUR): Serum creatinine
Study 14672612 — Safety Biomarker (SAF): Hyaluronic acid
Study 31450175 — Surrogate Endpoint (SUR): Blood pressure
Study 16516013 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 28768627 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 28848330 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17130977 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12757115 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12757115 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3546120 — Surrogate Endpoint (SUR): Blood pressure
Study 3546120 — Surrogate Endpoint (SUR): Serum sodium
Study 29016675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19799601 — Surrogate Endpoint (SUR): Blood pressure
Study 9258804 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 9258804 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 29668919 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 27527391 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 10202820 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22981148 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17239677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17239677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9737643 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2456776 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23833849 — Surrogate Endpoint (SUR): Blood pressure
Study 25294887 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 22574584 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31111923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15311722 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15311722 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29931604 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 25229983 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 16113753 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 16113753 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 26536327 — Surrogate Endpoint (SUR): Blood pressure
Study 18372278 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18372278 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12881382 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8743521 — Surrogate Endpoint (SUR): Blood pressure
Study 8743521 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15226470 — Safety Biomarker (SAF): MTHFR
Study 30616482 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30616482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30616482 — Safety Biomarker (SAF): BDNF
Study 27363313 — Predictive Biomarker (PRD): GLI2 mRNA
Genes: GLI2; THP
Study 27363313 — Surrogate Endpoint (SUR): Blood pressure
Study 21704236 — Surrogate Endpoint (SUR): Serum creatinine
Study 21704236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14723628 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 8222499 — Surrogate Endpoint (SUR): Blood pressure
Study 20066450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18679412 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18679412 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2948441 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24528605 — Surrogate Endpoint (SUR): Blood pressure
Study 20008644 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20008644 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 20008644 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23467860 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 2275326 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7267490 — Surrogate Endpoint (SUR): Blood pressure
Study 16732752 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 7537364 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 30882604 — Surrogate Endpoint (SUR): Blood pressure
Study 26686406 — Predictive Biomarker (PRD): SLAMF7 mRNA
Genes: SLAMF7; CS1; UNQ576/PRO1138
Study 21434845 — Surrogate Endpoint (SUR): Bone mineral density
Study 19747744 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 12626436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2447411 — Surrogate Endpoint (SUR): Blood pressure
Study 24089073 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 24089073 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21178422 — Monitoring Biomarker (MOI): Procalcitonin
Study 19370038 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19370038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19370038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19370038 — Surrogate Endpoint (SUR): Bone mineral density
Study 19370038 — Surrogate Endpoint (SUR): Blood pressure
Study 12860938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 7699532 — Surrogate Endpoint (SUR): Serum calcium
Study 7699532 — Surrogate Endpoint (SUR): Bone mineral density
Study 2568663 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2568663 — Surrogate Endpoint (SUR): Blood pressure
Study 31503037 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 8093363 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26663817 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 18174779 — Surrogate Endpoint (SUR): Blood pressure
Study 7587910 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 7587910 — Surrogate Endpoint (SUR): Blood pressure
Study 12076231 — Surrogate Endpoint (SUR): Blood pressure
Study 2490827 — Surrogate Endpoint (SUR): Blood pressure
Study 30210819 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24742739 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24742739 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 20232280 — Predictive Biomarker (PRD): TNFA
Genes: TNF; TNFSF2; DIF; TNF-alpha
Study 20232280 — Surrogate Endpoint (SUR): Serum sodium
Study 2197635 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 27905522 — Monitoring Biomarker (MOI): Cell-free DNA
Study 15717255 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15717255 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12843161 — Surrogate Endpoint (SUR): Serum testosterone
Study 12843161 — Surrogate Endpoint (SUR): Bone mineral density
Study 3905392 — Surrogate Endpoint (SUR): Blood pressure
Study 12915645 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 12915645 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22409711 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6370028 — Surrogate Endpoint (SUR): Blood pressure
Study 27806551 — Surrogate Endpoint (SUR): Blood pressure
Study 11966665 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9150773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7965153 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 27914504 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24444992 — Surrogate Endpoint (SUR): Blood pressure
Study 20105282 — Predictive Biomarker (PRD): SGK1 mRNA
Genes: SGK1; SGK
Study 18086006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11083305 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 8775571 — Surrogate Endpoint (SUR): Blood pressure
Study 24657956 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15853102 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 26445094 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 16879213 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 16879213 — Predictive Biomarker (PRD): PTGER4 mRNA
Genes: PTGER4; PTGER2
Study 16879213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11018616 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1893906 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1893906 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 27590454 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23935745 — Predictive Biomarker (PRD): FDX1 mRNA
Genes: FDX1; ADX
Study 8996846 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8996846 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 8996846 — Surrogate Endpoint (SUR): Blood pressure
Study 26242288 — Surrogate Endpoint (SUR): Blood pressure
Study 24918789 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24918789 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20399815 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26329135 — Predictive Biomarker (PRD): HDAC6 mRNA
Genes: HDAC6; KIAA0901; JM21
Study 26329135 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 26329135 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17711616 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 8589139 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8589139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 387330 — Surrogate Endpoint (SUR): Blood pressure
Study 25892082 — Surrogate Endpoint (SUR): Blood pressure
Study 22343209 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 17265094 — Surrogate Endpoint (SUR): Blood pressure
Study 7842362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 27964843 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15617456 — Surrogate Endpoint (SUR): Blood pressure
Study 3016071 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29313359 — Surrogate Endpoint (SUR): Blood pressure
Study 27616034 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27616034 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3887553 — Predictive Biomarker (PRD): PIR mRNA
Genes: PIR
Study 26780107 — Monitoring Biomarker (MOI): HBV DNA
Study 25577838 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19469746 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 8625251 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 18416851 — Surrogate Endpoint (SUR): Blood pressure
Study 15722689 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12764232 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 12764232 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12764232 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 10815850 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 1596562 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30844656 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29902979 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23015069 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23015069 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 23015069 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2