TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21696359 — Surrogate Endpoint (SUR): Blood pressure
Study 3388405 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 31135225 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12580930 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6908098 — Surrogate Endpoint (SUR): Blood pressure
Study 31838445 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 6125193 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23106658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15124243 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 7898332 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2796855 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28521717 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23881421 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15028823 — Surrogate Endpoint (SUR): Bone mineral density
Study 9124619 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8129541 — Surrogate Endpoint (SUR): Blood pressure
Study 24942709 — Surrogate Endpoint (SUR): Blood pressure
Study 22166162 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 7769295 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 7769295 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 94616 — Surrogate Endpoint (SUR): Blood pressure
Study 94616 — Surrogate Endpoint (SUR): Serum potassium
Study 6195479 — Surrogate Endpoint (SUR): Blood pressure
Study 19833819 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 40798 — Surrogate Endpoint (SUR): Blood pressure
Study 31671219 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 31671219 — Predictive Biomarker (PRD): STAMBP mRNA
Genes: STAMBP; AMSH
Study 31671219 — Predictive Biomarker (PRD): AXIN1 mRNA
Genes: AXIN1; AXIN
Study 31671219 — Predictive Biomarker (PRD): CASP8 mRNA
Genes: CASP8; MCH5
Study 31671219 — Predictive Biomarker (PRD): CD6 mRNA
Genes: CD6
Study 31671219 — Predictive Biomarker (PRD): CDCP1 mRNA
Genes: CDCP1; TRASK; UNQ2486/PRO5773
Study 31671219 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 31671219 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 31671219 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 31671219 — Predictive Biomarker (PRD): CSF1 mRNA
Genes: CSF1
Study 31671219 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL6 mRNA
Genes: CXCL6; GCP2; SCYB6
Study 19785568 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19785568 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31402538 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study 31402538 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27658659 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 27658659 — Safety Biomarker (SAF): Reactive oxygen species
Study 21568075 — Surrogate Endpoint (SUR): Blood pressure
Study 8851570 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24939671 — Surrogate Endpoint (SUR): Blood pressure
Study 27006237 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27006237 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 28671879 — Surrogate Endpoint (SUR): Blood pressure
Study 27112612 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 94638 — Surrogate Endpoint (SUR): Blood pressure
Study 28153005 — Surrogate Endpoint (SUR): Blood pressure
Study 26616798 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 9580646 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 28466507 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18173345 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 14691773 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28662152 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 26425078 — Surrogate Endpoint (SUR): Blood pressure
Study 21543543 — Surrogate Endpoint (SUR): Bone mineral density
Study 16959618 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15221622 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 3677365 — Surrogate Endpoint (SUR): Blood pressure
Study 26809111 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 17287681 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 2851414 — Surrogate Endpoint (SUR): Blood pressure
Study 24168107 — Predictive Biomarker (PRD): SLC22A4
Genes: OCTN1; MGC34546
Study 20004464 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28513877 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22003288 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22003288 — Surrogate Endpoint (SUR): Blood pressure
Study 22003288 — Surrogate Endpoint (SUR): Serum potassium
Study 18584198 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18584198 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17310820 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25853876 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 29070467 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29070467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29070467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22254404 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 16702490 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7540231 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7540231 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21499182 — Surrogate Endpoint (SUR): Blood pressure
Study 19932775 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26455498 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 26455498 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 3894101 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 12819556 — Surrogate Endpoint (SUR): Blood pressure
Study 10494188 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 21066889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21066889 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21066889 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11228175 — Surrogate Endpoint (SUR): Serum calcium
Study 11228175 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24078198 — Surrogate Endpoint (SUR): Blood pressure
Study 17510682 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17510682 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10076899 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 10076899 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 28941314 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 9663913 — Surrogate Endpoint (SUR): Blood pressure
Study 7923656 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30088425 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24150547 — Surrogate Endpoint (SUR): Blood pressure
Study 12852711 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 26372680 — Predictive Biomarker (PRD): CHIT1 mRNA
Genes: CHIT1
Study 26372680 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 21149331 — Predictive Biomarker (PRD): SFRP1 mRNA
Genes: SFRP1; FRP; FRP1; SARP2
Study 21149331 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17353040 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12186498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12186498 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18420939 — Surrogate Endpoint (SUR): Bone mineral density
Study 17585662 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16304265 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 6340415 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10911006 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 1330127 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 31024557 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 31024557 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31024557 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 12187500 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7529484 — Surrogate Endpoint (SUR): Serum creatinine
Study 27006512 — Surrogate Endpoint (SUR): Blood pressure
Study 25073015 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 26936842 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21360202 — Surrogate Endpoint (SUR): Blood pressure
Study 31630153 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31630153 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 31630153 — Pharmacodynamic Biomarker (PDY): Cytokine ML-1
Genes: IL17F
Study 31630153 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 23343906 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3056476 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21729518 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18834457 — Surrogate Endpoint (SUR): Blood pressure
Study 17209788 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 9728228 — Safety Biomarker (SAF): Interleukin 1
Study 9728228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16583234 — Surrogate Endpoint (SUR): Bone mineral density
Study 27401475 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16216721 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 1981022 — Surrogate Endpoint (SUR): Blood pressure
Study 26386540 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23714362 — Surrogate Endpoint (SUR): Blood pressure
Study 15657502 — Surrogate Endpoint (SUR): Blood pressure
Study 7476342 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31605877 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 14555565 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22982903 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22982903 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16786754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23848167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23848167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17585029 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17585029 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17585029 — Predictive Biomarker (PRD): Hormone receptor
Study 8922769 — Surrogate Endpoint (SUR): Blood pressure
Study 3892345 — Surrogate Endpoint (SUR): Serum potassium
Study 30219843 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 19125989 — Surrogate Endpoint (SUR): Bone mineral density
Study 31197264 — Surrogate Endpoint (SUR): Blood pressure
Study 31197264 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31197264 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18708148 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 26158769 — Surrogate Endpoint (SUR): Blood pressure
Study 18296978 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15110129 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11346861 — Surrogate Endpoint (SUR): Serum calcium
Study 9212042 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9212042 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7963146 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14631328 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 28745999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26287338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19906454 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19906454 — Predictive Biomarker (PRD): CASP3 mRNA
Genes: CASP3; CPP32
Study 19906454 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 1629885 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1629885 — Surrogate Endpoint (SUR): Blood pressure
Study 18756970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18756970 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18756970 — Safety Biomarker (SAF): Interleukin 12
Study 15247556 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15247556 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 15247556 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 11243418 — Surrogate Endpoint (SUR): Blood pressure
Study 29423947 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 29423947 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19713947 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30082170 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26920573 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27950535 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27950535 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 14551182 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15702134 — Predictive Biomarker (PRD): GABRA2 mRNA
Genes: GABRA2
Study 28872752 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 22158066 — Surrogate Endpoint (SUR): Blood pressure
Study 20120778 — Surrogate Endpoint (SUR): Serum creatinine
Study 20120778 — Safety Biomarker (SAF): Urinary total protein
Study 20120778 — Surrogate Endpoint (SUR): Serum potassium
Study 20120778 — Surrogate Endpoint (SUR): Blood pressure
Study 17473072 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17473072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16413428 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11216493 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9328363 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 8405026 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8405026 — Surrogate Endpoint (SUR): Blood pressure
Study 3533372 — Surrogate Endpoint (SUR): Serum creatinine
Study 20505016 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 18216523 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 3166044 — Surrogate Endpoint (SUR): Blood pressure
Study 28039082 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 21872843 — Surrogate Endpoint (SUR): Blood pressure
Study 17805064 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 8589024 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study 2102134 — Surrogate Endpoint (SUR): Blood pressure
Study 31075314 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 21828950 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 21828950 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19854375 — Surrogate Endpoint (SUR): Blood pressure
Study 15911731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19710195 — Surrogate Endpoint (SUR): Blood pressure
Study 3408634 — Surrogate Endpoint (SUR): Blood pressure
Study 17081400 — Surrogate Endpoint (SUR): Blood pressure
Study 17081400 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29679660 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29679660 — Safety Biomarker (SAF): BDNF
Study 24662322 — Surrogate Endpoint (SUR): Blood pressure
Study 22168128 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 17510208 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17510208 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 3882071 — Surrogate Endpoint (SUR): Serum creatinine
Study 23846567 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7832387 — Predictive Biomarker (PRD): RHCE mRNA
Genes: RHCE; RHC; RHE
Study 1977080 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 344850 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 30870235 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 26686385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9459332 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9459332 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7572573 — Surrogate Endpoint (SUR): Blood pressure
Study 25375780 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 21772125 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21772125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21772125 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18931896 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18931896 — Surrogate Endpoint (SUR): Blood pressure
Study 7768249 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18806833 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18806833 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17141945 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17141945 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 15090958 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27490086 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 9001838 — Surrogate Endpoint (SUR): Blood pressure
Study 27021751 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27021751 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17268413 — Surrogate Endpoint (SUR): Blood pressure
Study 23952326 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11922111 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 29393237 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 25056504 — Surrogate Endpoint (SUR): Serum creatinine
Study 1955620 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1955620 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24596459 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18066133 — Surrogate Endpoint (SUR): Blood pressure
Study 19828532 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19828532 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15605372 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 12460877 — Surrogate Endpoint (SUR): Blood pressure
Study 31925809 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31925809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26749529 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18538098 — Predictive Biomarker (PRD): CNDP2 mRNA
Genes: CNDP2; CN2; CPGL; HEL-S-13; PEPA
Study 26700214 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23852695 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 20137768 — Surrogate Endpoint (SUR): Blood pressure
Study 18030231 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 11902250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30513347 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 19060001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19060001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15570242 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 15570242 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 9633671 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 23537708 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18188694 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18188694 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16896785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16896785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7514237 — Predictive Biomarker (PRD): AIRE mRNA
Genes: AIRE; APECED
Study 18460201 — Surrogate Endpoint (SUR): Blood pressure
Study 12663512 — Predictive Biomarker (PRD): OGG1 mRNA
Genes: OGG1; MMH; MUTM; OGH1
Study 12663512 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 10887107 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10887107 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 1551634 — Monitoring Biomarker (MOI): HBV DNA
Study 2860044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18044288 — Surrogate Endpoint (SUR): Blood pressure