TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03370653 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT03479372 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03892785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01733056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01920451 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01688700 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01688700 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05027165 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03553810 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04697940 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04697940 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04697940 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT04087148 — Predictive Biomarker (PRD): CYP21A2 mRNA
Genes: CYP21A2; CYP21; CYP21B
Study NCT04087148 — Predictive Biomarker (PRD): HSD3B2 mRNA
Genes: HSD3B2; HSDB3B
Study NCT04087148 — Safety Biomarker (SAF): CYP11B1 mRNA
Genes: CYP11B1; S11BH
Study NCT01329367 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study NCT04026776 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02187991 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02187991 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02187991 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02187991 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT02285582 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT01149928 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT01203735 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT01744249 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00198562 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01983410 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT02639130 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03905889 — Predictive Biomarker (PRD): PIM1 mRNA
Genes: PIM1
Study NCT03905889 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03974477 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05896605 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT00737126 — Safety Biomarker (SAF): MTHFR
Study NCT02159495 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT02159495 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03816748 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00617942 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00563901 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04236102 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT04236102 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04236102 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04236102 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01634776 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study NCT02726620 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03395899 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03085485 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01457365 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02504983 — Predictive Biomarker (PRD): GALNT14 mRNA
Genes: GALNT14; UNQ2434/PRO4994
Study NCT00371189 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04977882 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03148366 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04136821 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04184284 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT04184284 — Predictive Biomarker (PRD): IL5RA mRNA
Genes: IL5RA; IL5R
Study NCT02238821 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04415320 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03073239 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT01069653 — Predictive Biomarker (PRD): KIF20A mRNA
Genes: KIF20A; MKLP2; RAB6KIFL
Study NCT01069653 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT03940703 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT03940703 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03940703 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04215211 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT01741766 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00532441 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00532441 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03798509 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02862743 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT02862743 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03743805 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01208389 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT01578473 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT03330405 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03330405 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01459484 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT00890825 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00806910 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT00588978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03293459 — Surrogate Endpoint (SUR): Plasma ammonia
Study NCT02950051 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT00734357 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00165204 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01056497 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01600898 — Predictive Biomarker (PRD): BMPR2 mRNA
Genes: BMPR2; PPH1
Study NCT00750724 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01966367 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01597414 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00608868 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00092209 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02314299 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT01384123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01384123 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01384123 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00019175 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02360826 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study NCT03865927 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02977572 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study NCT04647006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04647006 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04647006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03649061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04546308 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04546308 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT05065905 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01345760 — Predictive Biomarker (PRD): TARBP1 mRNA
Genes: TARBP1; TRM3; TRP185
Study NCT01345760 — Predictive Biomarker (PRD): TARBP2 mRNA
Genes: TARBP2; TRBP
Study NCT01345760 — Predictive Biomarker (PRD): PRKRA mRNA
Genes: PRKRA; PACT; RAX; HSD-14; HSD14
Study NCT03477773 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02941900 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study NCT01454596 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01454596 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00440362 — Surrogate Endpoint (SUR): Serum antibody concentration
Study NCT00006483 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03073720 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT03968380 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03494764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01971801 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02449551 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02449551 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT01043770 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02119416 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01432587 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT04227678 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT00999453 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04263311 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03814148 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03013075 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00697645 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00697645 — Safety Biomarker (SAF): BDNF
Study NCT04618185 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02063373 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00346541 — Safety Biomarker (SAF): Interleukin 1
Study NCT01260844 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01260844 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01260844 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01260844 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02299414 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02467504 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00596700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03638167 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02880865 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01044225 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00741533 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT02975934 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT02724631 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT04625179 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01074060 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01074060 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT03549546 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03644186 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03644186 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02638948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01329627 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01329627 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00840853 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03455556 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01705665 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT01653678 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04185038 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study NCT02696876 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04422574 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04310930 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT03536806 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01293045 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01293045 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT04362943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04030364 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study NCT02768532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00307112 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT00795535 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03325517 — Predictive Biomarker (PRD): MCM4 mRNA
Genes: MCM4; CDC21
Study NCT03325517 — Predictive Biomarker (PRD): MCM3 mRNA
Genes: MCM3
Study NCT00274638 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00550953 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00862134 — Predictive Biomarker (PRD): AKR1C3 mRNA
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study NCT02101736 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT03796858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02346045 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01140958 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04558658 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT00603330 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00603330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study NCT01332630 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study NCT00706953 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03241927 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03934372 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03934372 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03620058 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03620058 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03101748 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00001534 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01221987 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT05283317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02158676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01134068 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01527058 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01527058 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01527058 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02738866 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02738866 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02738866 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03803956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03803956 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT03803956 — Safety Biomarker (SAF): Interleukin 1
Study NCT03803956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00764465 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT01903967 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01903967 — Predictive Biomarker (PRD): PTTG1
Genes: PTTG; HPTTG; EAP1; securin; ECRAR
Study NCT01903967 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT01978327 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT01978327 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00099684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02636725 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT00145080 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00962624 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study NCT00972660 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01288911 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01288911 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00556465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00556465 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03746106 — Predictive Biomarker (PRD): SLC19A3 mRNA
Genes: SLC19A3
Study NCT04671966 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00410956 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03101839 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03569241 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03636971 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02774824 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT04511533 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04511533 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00348283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00280540 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04028934 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT02365922 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT00277303 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT00277303 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01718457 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03277729 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04141059 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study NCT04141059 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT04141059 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study NCT02892526 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT02892526 — Safety Biomarker (SAF): miR-9
Study NCT02892526 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT05568433 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT05568433 — Predictive Biomarker (PRD): HMGA2 mRNA
Genes: HMGA2; HMGIC
Study NCT05568433 — Safety Biomarker (SAF): Interleukin 1
Study NCT01308242 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04794361 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03526822 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study NCT03526822 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT03526822 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03526822 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT03526822 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT03526822 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT03526822 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01384994 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01384994 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02275676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00990691 — Predictive Biomarker (PRD): MECP2 mRNA
Genes: MECP2
Study NCT03849677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02789761 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03767829 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209