TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20809272 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11158071 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9243225 — Surrogate Endpoint (SUR): Blood pressure
Study 19912212 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 22850440 — Surrogate Endpoint (SUR): Blood pressure
Study 18534218 — Surrogate Endpoint (SUR): Serum creatinine
Study 3545629 — Surrogate Endpoint (SUR): Blood pressure
Study 24476416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24476416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22710953 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15978098 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 12115946 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2299367 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 2299367 — Predictive Biomarker (PRD): RTN1 mRNA
Genes: RTN1; NSP
Study 21829903 — Surrogate Endpoint (SUR): Blood pressure
Study 19788487 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 17086018 — Surrogate Endpoint (SUR): Blood pressure
Study 11700183 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11700183 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3111339 — Predictive Biomarker (PRD): PTGDS mRNA
Genes: PTGDS; PDS
Study 29513931 — Predictive Biomarker (PRD): ICOSLG mRNA
Genes: ICOSLG; B7H2; B7RP1; ICOSL; KIAA0653
Study 27271554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27271554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27271554 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17440525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17440525 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31801673 — Predictive Biomarker (PRD): C6orf15 mRNA
Genes: C6orf15; STG; UNQ1840/PRO3566
Study 27209439 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22422823 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 14581795 — Surrogate Endpoint (SUR): Plasma ammonia
Study 2578880 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 10480630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10480630 — Safety Biomarker (SAF): Interleukin 12
Study 8916820 — Surrogate Endpoint (SUR): Blood pressure
Study 6698443 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30270717 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27056766 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 24559020 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 16358550 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31484340 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 26869288 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 20682671 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 15353050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23883161 — Surrogate Endpoint (SUR): Blood pressure
Study 15957835 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 11818154 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30610279 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 19029962 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9425382 — Surrogate Endpoint (SUR): Serum creatinine
Study 24652221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21670770 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 15118522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8112439 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 21969505 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17955230 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 14665499 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26660707 — Surrogate Endpoint (SUR): Serum creatinine
Study 26660707 — Surrogate Endpoint (SUR): Serum sodium
Study 12215965 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 12215965 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 12215965 — Safety Biomarker (SAF): Reactive oxygen species
Study 30552176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26469827 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9407564 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7712700 — Surrogate Endpoint (SUR): Blood pressure
Study 2575550 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 855911 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 31577341 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 20587028 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18071056 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 18071056 — Predictive Biomarker (PRD): ADRA2C mRNA
Genes: ADRA2C; ADRA2L2; ADRA2RL2
Study 15910204 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 1972557 — Surrogate Endpoint (SUR): Blood pressure
Study 387057 — Surrogate Endpoint (SUR): Serum uric acid
Study 387057 — Surrogate Endpoint (SUR): Serum potassium
Study 23552356 — Surrogate Endpoint (SUR): Blood pressure
Study 19930615 — Surrogate Endpoint (SUR): Blood pressure
Study 11166518 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9154767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24602844 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17766190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16741879 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29855172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17488511 — Surrogate Endpoint (SUR): Blood pressure
Study 15036181 — Surrogate Endpoint (SUR): Bone mineral density
Study 29382794 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 10582989 — Surrogate Endpoint (SUR): Blood pressure
Study 8572357 — Surrogate Endpoint (SUR): Blood pressure
Study 31086222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31086222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25491475 — Surrogate Endpoint (SUR): Serum sodium
Study 21114416 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 14519751 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 10657575 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24907225 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 22996850 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 17660157 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17660157 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 10199766 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10809240 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 10809240 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27367818 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27367818 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22901620 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12506171 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30500646 — Surrogate Endpoint (SUR): Blood pressure
Study 25087085 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23166062 — Surrogate Endpoint (SUR): Blood pressure
Study 9059091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9059091 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 9059091 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9059091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30060980 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30060980 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 27486544 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17109733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 17109733 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17109733 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12468113 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 12468113 — Surrogate Endpoint (SUR): Blood pressure
Study 16411386 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 16411386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16411386 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7657130 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 28323838 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 24112970 — Surrogate Endpoint (SUR): Blood pressure
Study 15538132 — Surrogate Endpoint (SUR): Blood pressure
Study 31175364 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 25962601 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 25962601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25962601 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 25962601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17855815 — Safety Biomarker (SAF): Interleukin 1
Study 17855815 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17855815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17855815 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10708840 — Predictive Biomarker (PRD): TYRO3 mRNA
Genes: TYRO3; BYK; DTK; RSE; SKY; TIF
Study 6370150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6370150 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31126337 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 14742990 — Surrogate Endpoint (SUR): Serum creatinine
Study 7915442 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23816766 — Safety Biomarker (SAF): Th2 cell
Study 15180356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9350072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17199952 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 10403579 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 30089792 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25972244 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25972244 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22517610 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16283381 — Predictive Biomarker (PRD): CPT1A mRNA
Genes: CPT1A; CPT1
Study 16283381 — Predictive Biomarker (PRD): SLC22A5 mRNA
Genes: SLC22A5; OCTN2
Study 12586132 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 9825354 — Surrogate Endpoint (SUR): Blood pressure
Study 30241318 — Safety Biomarker (SAF): BDNF
Study 30785826 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30785826 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30785826 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30785826 — Predictive Biomarker (PRD): Hormone receptor
Study 27986874 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 19474053 — Surrogate Endpoint (SUR): Blood pressure
Study 2880663 — Surrogate Endpoint (SUR): Blood pressure
Study 19234585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19234585 — Surrogate Endpoint (SUR): Bone mineral density
Study 10636263 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8615492 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31405365 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 24490806 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 26299563 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19952828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10541503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29061568 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 29061568 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22612620 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20299988 — Surrogate Endpoint (SUR): Blood pressure
Study 17999638 — Surrogate Endpoint (SUR): Blood pressure
Study 30092143 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27481884 — Safety Biomarker (SAF): Hyaluronic acid
Study 22870245 — Predictive Biomarker (PRD): HMBS mRNA
Genes: HMBS; PBGD; UPS
Study 2162633 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27458066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26330658 — Surrogate Endpoint (SUR): Blood pressure
Study 24304724 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24304724 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 11340683 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11340683 — Surrogate Endpoint (SUR): Serum creatinine
Study 23883922 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 3115779 — Surrogate Endpoint (SUR): Blood pressure
Study 18764913 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26908565 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23733031 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23733031 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20626325 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 17162430 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29346503 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18081861 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 18081861 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8578808 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17293228 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27880977 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 24175566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24175566 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24175566 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24175566 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10873409 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22945709 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23099809 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 17955458 — Predictive Biomarker (PRD): CHRNA4 mRNA
Genes: CHRNA4; NACRA4
Study 17955458 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 17653259 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 26259981 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 22241602 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12214257 — Surrogate Endpoint (SUR): Blood pressure
Study 194679 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 30527256 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 26699597 — Surrogate Endpoint (SUR): Blood pressure
Study 25179977 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25179977 — Surrogate Endpoint (SUR): Serum creatinine
Study 22154118 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22154118 — Predictive Biomarker (PRD): Hormone receptor
Study 16305563 — Surrogate Endpoint (SUR): Blood pressure
Study 6756931 — Surrogate Endpoint (SUR): Blood pressure
Study 11899174 — Surrogate Endpoint (SUR): Serum creatinine
Study 8174846 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 27429596 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 19114685 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19114685 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17709802 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31799875 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 25552408 — Surrogate Endpoint (SUR): Sperm parameters
Study 17223872 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17223872 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 17223872 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15643131 — Surrogate Endpoint (SUR): Blood pressure
Study 15643131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11881123 — Surrogate Endpoint (SUR): Blood pressure
Study 8173308 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 22254084 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12885805 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12458394 — Surrogate Endpoint (SUR): Blood pressure
Study 10362195 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27793071 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 17347447 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 17347447 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 17347447 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 17189547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8427429 — Surrogate Endpoint (SUR): Blood pressure
Study 3478618 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29172732 — Surrogate Endpoint (SUR): Blood pressure
Study 26648488 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 6084120 — Surrogate Endpoint (SUR): Blood pressure
Study 17844705 — Surrogate Endpoint (SUR): Blood pressure
Study 9447852 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 25336114 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16314626 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29936923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7677557 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7677557 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2206826 — Surrogate Endpoint (SUR): Blood pressure
Study 25742919 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15276536 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15276536 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11518200 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24917631 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12624625 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 11728289 — Surrogate Endpoint (SUR): Blood pressure
Study 26427112 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 26427112 — Surrogate Endpoint (SUR): Serum creatinine
Study 26427112 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 17157397 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17157397 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9472784 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 2227107 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2227107 — Surrogate Endpoint (SUR): Blood pressure
Study 30635033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25439076 — Surrogate Endpoint (SUR): Blood pressure
Study 25439076 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21386797 — Surrogate Endpoint (SUR): Blood pressure
Study 21386797 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23317049 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 16750341 — Surrogate Endpoint (SUR): Bone mineral density
Study 12875936 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1487551 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD