TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25830947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12953851 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12953851 — Surrogate Endpoint (SUR): Blood pressure
Study 27007919 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 27007919 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9305340 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11191542 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 31044227 — Surrogate Endpoint (SUR): Blood pressure
Study 30180755 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 22040465 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 16045524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16045524 — Predictive Biomarker (PRD): PIBF1 mRNA
Genes: PIBF1; C13orf24; PIBF
Study 16045524 — Safety Biomarker (SAF): IL-6 and IL-10
Study 25014686 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16722024 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15373932 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 8717802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3901562 — Surrogate Endpoint (SUR): Blood pressure
Study 26169611 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 26169611 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26169611 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 14667875 — Surrogate Endpoint (SUR): Sperm parameters
Study 27009617 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22235820 — Surrogate Endpoint (SUR): Blood pressure
Study 22235820 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17470723 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17470723 — Surrogate Endpoint (SUR): Blood pressure
Study 10771928 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 30897999 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12670123 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1665118 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FLNA mRNA
Genes: FLNA; FLN; FLN1
Study 31743793 — Surrogate Endpoint (SUR): Blood pressure
Study 28818674 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 1342280 — Surrogate Endpoint (SUR): Blood pressure
Study 31535213 — Surrogate Endpoint (SUR): Blood pressure
Study 31535213 — Surrogate Endpoint (SUR): Serum calcium
Study 20160396 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24213610 — Surrogate Endpoint (SUR): Blood pressure
Study 23341531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31562496 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30761795 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22493910 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 12752560 — Surrogate Endpoint (SUR): Blood pressure
Study 21282542 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21282542 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9429989 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25110222 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9215820 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 9215820 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20814324 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 15465981 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31182492 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21167347 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21167347 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25127011 — Surrogate Endpoint (SUR): Bone mineral density
Study 22325683 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1710009 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 21608221 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21608221 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 24097171 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 20534765 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11517126 — Pharmacodynamic Biomarker (PDY): Central beta power
Study 18707846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18707846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18707846 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16939405 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 9108387 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9108387 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9108387 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8211871 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 23131288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23131288 — Monitoring Biomarker (MOI): Procalcitonin
Study 23131288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23131288 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20367218 — Surrogate Endpoint (SUR): Blood pressure
Study 12667024 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12667024 — Surrogate Endpoint (SUR): Serum creatinine
Study 10372238 — Surrogate Endpoint (SUR): Blood pressure
Study 22054782 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24134922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15320475 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 29884132 — Predictive Biomarker (PRD): FZD10 mRNA
Genes: FZD10
Study 24529697 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 24529697 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 24529697 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): miR-124
Study 16014854 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 28641407 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28641407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19506137 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16469978 — Surrogate Endpoint (SUR): Blood pressure
Study 30287523 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30287523 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 26107742 — Surrogate Endpoint (SUR): Blood pressure
Study 21123460 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 21123460 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11590486 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3598997 — Surrogate Endpoint (SUR): Blood pressure
Study 27117555 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 17900457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26084554 — Safety Biomarker (SAF): Hyaluronic acid
Study 10394092 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 17135598 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 17135598 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 17135598 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 18234715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18234715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10078678 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 24404819 — Surrogate Endpoint (SUR): Blood pressure
Study 15993724 — Surrogate Endpoint (SUR): Blood pressure
Study 14687872 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2870610 — Surrogate Endpoint (SUR): Blood pressure
Study 28661316 — Surrogate Endpoint (SUR): Blood pressure
Study 21703206 — Monitoring Biomarker (MOI): HBV DNA
Study 19307526 — Surrogate Endpoint (SUR): Blood pressure
Study 10412755 — Safety Biomarker (SAF): Reactive oxygen species
Study 10412755 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6772366 — Surrogate Endpoint (SUR): Serum calcium
Study 27552585 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 25712685 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 25712685 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 11078982 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 10373047 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9441116 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9441116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 1417133 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6391270 — Surrogate Endpoint (SUR): Blood pressure
Study 30832722 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 30832722 — Safety Biomarker (SAF): Hyaluronic acid
Study 27417007 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24779961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24779961 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 24779961 — Safety Biomarker (SAF): Interleukin 1
Study 24779961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10482995 — Predictive Biomarker (PRD): CD58 mRNA
Genes: CD58; LFA3
Study 25044235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25044235 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25044235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1728908 — Surrogate Endpoint (SUR): Blood pressure
Study 6142878 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6142878 — Surrogate Endpoint (SUR): Blood pressure
Study 28976114 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 23962572 — Surrogate Endpoint (SUR): Blood pressure
Study 12471862 — Surrogate Endpoint (SUR): Blood pressure
Study 31051508 — Predictive Biomarker (PRD): NR1H3 mRNA
Genes: NR1H3; LXRA
Study 31051508 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 31051508 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 31051508 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor delta
Genes: PPARD
Study 31051508 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23075919 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29950827 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24410954 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 24410954 — Safety Biomarker (SAF): Interleukin 1
Study 30280927 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 31329360 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24238592 — Surrogate Endpoint (SUR): Blood pressure
Study 28751562 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24045625 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 10831645 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 31344185 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 10436948 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 14689713 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 10953903 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10953903 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1314144 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 19707983 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19707983 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8653553 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8653553 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24784420 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23567146 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23567146 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3300841 — Surrogate Endpoint (SUR): Blood pressure
Study 12419088 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12419088 — Surrogate Endpoint (SUR): Blood pressure
Study 12419088 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31981712 — Surrogate Endpoint (SUR): Blood pressure
Study 23873699 — Surrogate Endpoint (SUR): Bone mineral density
Study 10754431 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 10754431 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 1385778 — Surrogate Endpoint (SUR): Blood pressure
Study 30520208 — Surrogate Endpoint (SUR): Serum testosterone
Study 23234350 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1824790 — Surrogate Endpoint (SUR): Serum testosterone
Study 1824790 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 3030386 — Surrogate Endpoint (SUR): Blood pressure
Study 27704631 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27704631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27704631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27704631 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21392105 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19401477 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19401477 — Surrogate Endpoint (SUR): Blood pressure
Study 15346695 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23300153 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23300153 — Surrogate Endpoint (SUR): Bone mineral density
Study 12771973 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8174729 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28533194 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25867743 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25867743 — Safety Biomarker (SAF): BDNF
Study 23276549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17945197 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25332100 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 19222849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19222849 — Monitoring Biomarker (MOI): Procalcitonin
Study 3436982 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 31736328 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29277839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29277839 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 27450419 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 27450419 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study 25703254 — Surrogate Endpoint (SUR): Blood pressure
Study 20172742 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 28681435 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25741582 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25741582 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25741582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23802768 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 23802768 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 14967075 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31603979 — Surrogate Endpoint (SUR): Blood pressure
Study 31603979 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15207440 — Surrogate Endpoint (SUR): Blood pressure
Study 27190088 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27838537 — Safety Biomarker (SAF): Hyaluronic acid
Study 20714373 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11923489 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7634976 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 7634976 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 28869987 — Surrogate Endpoint (SUR): Blood pressure
Study 23936562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19303414 — Monitoring Biomarker (MOI): HBV DNA
Study 16384840 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 20497961 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20497961 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20497961 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12382215 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 94266 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 31622732 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31622732 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31622732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 19576325 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19576325 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19576325 — Surrogate Endpoint (SUR): Blood pressure
Study 15262902 — Surrogate Endpoint (SUR): Blood pressure
Study 29909435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25050904 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 25050904 — Predictive Biomarker (PRD): SOCS2 mRNA
Genes: SOCS2; CIS2; SSI2; STATI2
Study 25050904 — Predictive Biomarker (PRD): CISH mRNA
Genes: CISH; G18
Study 16037146 — Surrogate Endpoint (SUR): Blood pressure
Study 25367310 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 25367310 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 25367310 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 25367310 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2537095 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25074688 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25453517 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 20933321 — Predictive Biomarker (PRD): PCA3
Study 11871742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11871742 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11092663 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26584888 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26584888 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26584888 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 12579174 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29562597 — Surrogate Endpoint (SUR): Blood pressure
Study 25248910 — Surrogate Endpoint (SUR): Blood pressure
Study 25248910 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 739228 — Predictive Biomarker (PRD): ACHE mRNA
Genes: ACHE
Study 739228 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 10694560 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10694560 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10694560 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 3005801 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31870463 — Surrogate Endpoint (SUR): Blood pressure
Study 12069361 — Surrogate Endpoint (SUR): Blood pressure
Study 12069361 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12069361 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31472687 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM