TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00056979 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT00056979 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT00677534 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT01560312 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02172638 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT02931357 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00509249 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01527747 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00327262 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00327262 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00783822 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00783822 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03505164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03505164 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04450108 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03896334 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00396110 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04005118 — Predictive Biomarker (PRD): HACE1 mRNA
Genes: HACE1; KIAA1320
Study NCT01624077 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02650089 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04192981 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04192981 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT00341341 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study NCT03266159 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT03266159 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study NCT03266159 — Safety Biomarker (SAF): RAS pathway
Study NCT03568864 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT04383353 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02371317 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01068665 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01613482 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03851302 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03851302 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01059734 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study NCT03724929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00820469 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00717509 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study NCT03472079 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study NCT03472079 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT04089761 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT04112004 — Surrogate Endpoint (SUR): Serum sodium
Study NCT04049162 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00489606 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT04353752 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01926834 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02205034 — Predictive Biomarker (PRD): MAGEL2 mRNA
Genes: MAGEL2; NDNL1
Study NCT01722370 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT00479713 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05332847 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02901067 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT00737698 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT03660332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03877601 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03877601 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01755572 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03953794 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study NCT01361542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01361542 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02459444 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT02710175 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02710175 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00781105 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01579994 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03780361 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT00630734 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study NCT03018522 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT00211198 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00733629 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00435175 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01042925 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01042925 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01042925 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03881735 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT01455532 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT02856048 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04640233 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02207920 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04501315 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT01606969 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04357834 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04357834 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01776918 — Safety Biomarker (SAF): POLG
Genes: POLG1; POLGA
Study NCT00085995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00085995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02408016 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT00310180 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04132817 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00655538 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00611000 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00611000 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study NCT03351647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03351647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03351647 — Safety Biomarker (SAF): Interleukin 12
Study NCT00040170 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT00040170 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00172835 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03950739 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04355403 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03557645 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03848039 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03890588 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03890588 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01708954 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01708954 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02068794 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT04927832 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study NCT02559739 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01065896 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03965494 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT03457532 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05736640 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01927783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01270178 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03648294 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03688178 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT04012619 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02090101 — Safety Biomarker (SAF): Interleukin 1
Study NCT02605980 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00492284 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03408405 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03408405 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02517177 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02517177 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03712878 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00278434 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT04567641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04567641 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00003113 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03310684 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03310684 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01025089 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study NCT01025089 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT00970138 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06303167 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02484417 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04568434 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03356639 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT03356639 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study NCT01491347 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01491347 — Safety Biomarker (SAF): BDNF
Study NCT03757936 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04029922 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00891267 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03641326 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02109367 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT02534909 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT02534909 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT01454583 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00088933 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00088933 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02444455 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02368249 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04282135 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04059263 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02697253 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT02697253 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT01355042 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT01978951 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05330832 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT03191630 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03523026 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01228318 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT00434902 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00434902 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT00434902 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00434902 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02815579 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03618420 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT03698851 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00724672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03561298 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03561298 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT03561298 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03561298 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT03257124 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00224952 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT01450059 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03480477 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02209493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03544021 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04400487 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03559062 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01091857 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01037517 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03354936 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03819361 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04119167 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study NCT04656054 — Surrogate Endpoint (SUR): Serum potassium
Study NCT04656054 — Surrogate Endpoint (SUR): Serum sodium
Study NCT00280215 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03724253 — Predictive Biomarker (PRD): GRPR mRNA
Genes: GRPR
Study NCT01979406 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study NCT01294397 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01541852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01564108 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01564108 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03273335 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03986203 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01479868 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00354757 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04101643 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04101643 — Predictive Biomarker (PRD): CYP7B1 mRNA
Genes: CYP7B1
Study NCT02678351 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03638076 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03866590 — Predictive Biomarker (PRD): PKLR mRNA
Genes: PKLR; PK1; PKL
Study NCT01436370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01186705 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01186705 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04631731 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04631731 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT04631731 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04631731 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study NCT04631731 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00962637 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT01749969 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT01328704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02738749 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study NCT04386460 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03860857 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01768182 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03222089 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04649840 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04416048 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00863681 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03031496 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01380795 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01739036 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT02342158 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04053062 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04053062 — Predictive Biomarker (PRD): TNFSF14 mRNA
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study NCT04465955 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04014231 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01381757 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04154852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04300465 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02459457 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT03659838 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03659838 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03594760 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01531777 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01122303 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01699113 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study NCT04448626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04448626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04448626 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00476164 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00564759 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04040725 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT04040725 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT01696955 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02833675 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00356681 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02200653 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04163575 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT02347839 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02242474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02025179 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03123666 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03546556 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT02798939 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT04158804 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03759782 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00613899 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00295542 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03425201 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT03425201 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT03425201 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT03425201 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR