TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20710062 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9235548 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9235548 — Surrogate Endpoint (SUR): Blood pressure
Study 8426544 — Surrogate Endpoint (SUR): Blood pressure
Study 14512873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14512873 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30029896 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 24883322 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 2496668 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 31950036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17472817 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17472817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17472817 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10322832 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28763003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21791660 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 29753234 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18701824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18701824 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 12361449 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9681396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23968654 — Surrogate Endpoint (SUR): Blood pressure
Study 11164126 — Surrogate Endpoint (SUR): Blood pressure
Study 26077006 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21694649 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16642605 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 16642605 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10063814 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10063814 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 84706 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 84706 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 23798635 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 17121380 — Surrogate Endpoint (SUR): Serum uric acid
Study 3019375 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3019375 — Surrogate Endpoint (SUR): Blood pressure
Study 16990410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2525870 — Surrogate Endpoint (SUR): Blood pressure
Study 16539287 — Safety Biomarker (SAF): Hyaluronic acid
Study 10880059 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 8777472 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8777472 — Surrogate Endpoint (SUR): Blood pressure
Study 11098023 — Safety Biomarker (SAF): Reactive oxygen species
Study 11098023 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1442658 — Surrogate Endpoint (SUR): Blood pressure
Study 1442658 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29665087 — Surrogate Endpoint (SUR): Bone mineral density
Study 16845582 — Surrogate Endpoint (SUR): Blood pressure
Study 12790293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10666180 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 31204597 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31204597 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30278530 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24082784 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21390262 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25287282 — Surrogate Endpoint (SUR): Blood pressure
Study 31482307 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26161612 — Surrogate Endpoint (SUR): Blood pressure
Study 9116924 — Surrogate Endpoint (SUR): Blood pressure
Study 31825192 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24280596 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24280596 — Surrogate Endpoint (SUR): Serum creatinine
Study 21989792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20032491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17658091 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29719179 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 23481512 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23481512 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 23481512 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 16464787 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16464787 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8508864 — Surrogate Endpoint (SUR): Blood pressure
Study 24622243 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 11789969 — Surrogate Endpoint (SUR): Blood pressure
Study 31027435 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 25250647 — Surrogate Endpoint (SUR): Serum creatinine
Study 23348843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22097196 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22097196 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9646621 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2884706 — Surrogate Endpoint (SUR): Blood pressure
Study 21899803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18718423 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 18718423 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18718423 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10569330 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6313522 — Surrogate Endpoint (SUR): Blood pressure
Study 30217492 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 17300536 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 8815557 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 15035598 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 11475715 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 12773076 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3549583 — Surrogate Endpoint (SUR): Blood pressure
Study 21169087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12626213 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27956565 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 18355330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18355330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18355330 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18355330 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24902655 — Surrogate Endpoint (SUR): Blood pressure
Study 12882902 — Predictive Biomarker (PRD): COX4I1 mRNA
Genes: COX4I1; COX4
Study 12882902 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 12882902 — Predictive Biomarker (PRD): NKRF mRNA
Genes: NKRF; ITBA4; NRF
Study 12882902 — Predictive Biomarker (PRD): TFAM mRNA
Genes: TFAM; TCF6; TCF6L2
Study 12882902 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 12882902 — Safety Biomarker (SAF): Cytochrome c
Study 10429625 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 24842697 — Surrogate Endpoint (SUR): Blood pressure
Study 24842697 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12614246 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 21122628 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21122628 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6354100 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 24697580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24697580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22240336 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 17522328 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15172406 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11840581 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 31995239 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 27678453 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27678453 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27678453 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24937205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10591680 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10591680 — Surrogate Endpoint (SUR): Blood pressure
Study 10591680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10591680 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10591680 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10591680 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15784786 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 29858875 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 26775293 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26775293 — Safety Biomarker (SAF): BDNF
Study 20372089 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19060996 — Surrogate Endpoint (SUR): Blood pressure
Study 15916369 — Predictive Biomarker (PRD): EHF mRNA
Genes: EHF; ESE3; ESE3B; ESEJ
Study 20919 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29753703 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 9401096 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9401096 — Surrogate Endpoint (SUR): Blood pressure
Study 7957149 — Surrogate Endpoint (SUR): Blood pressure
Study 22412081 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20852375 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20852375 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18285430 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18285430 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 8855815 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27861379 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19562349 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 19562349 — Surrogate Endpoint (SUR): Serum creatinine
Study 19562349 — Surrogate Endpoint (SUR): Serum sodium
Study 9551707 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21424914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21424914 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21424914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18291276 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 1372723 — Surrogate Endpoint (SUR): Blood pressure
Study 29365083 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22266741 — Safety Biomarker (SAF): Hyaluronic acid
Study 17657474 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 16000279 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 8726616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8726616 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8726616 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 21929528 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 21929528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28069021 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28069021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21711059 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19139013 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 20615884 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 2671369 — Surrogate Endpoint (SUR): Blood pressure
Study 31512187 — Surrogate Endpoint (SUR): Blood pressure
Study 2884813 — Surrogate Endpoint (SUR): Blood pressure
Study 24928790 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29205286 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 8960444 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30974188 — Surrogate Endpoint (SUR): Blood pressure
Study 24727160 — Surrogate Endpoint (SUR): Bone mineral density
Study 17402960 — Surrogate Endpoint (SUR): Blood pressure
Study 23910201 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 7963760 — Safety Biomarker (SAF): Interleukin 1
Study 30449208 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 25123116 — Safety Biomarker (SAF): Hyaluronic acid
Study 15464329 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8984313 — Surrogate Endpoint (SUR): Blood pressure
Study 28957818 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18645727 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16842467 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22547605 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11476474 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 7937658 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16874169 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 8481936 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15531659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15531659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15531659 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23310947 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 21994424 — Surrogate Endpoint (SUR): Blood pressure
Study 2610719 — Surrogate Endpoint (SUR): Blood pressure
Study 26825032 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 18766955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18766955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10102781 — Surrogate Endpoint (SUR): Blood pressure
Study 8848903 — Surrogate Endpoint (SUR): Blood pressure
Study 21083855 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 27710972 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12519430 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23266540 — Surrogate Endpoint (SUR): Blood pressure
Study 17018383 — Predictive Biomarker (PRD): Liver iron
Study 11675899 — Surrogate Endpoint (SUR): Blood pressure
Study 11675899 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11675899 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20978741 — Surrogate Endpoint (SUR): Blood pressure
Study 8797125 — Surrogate Endpoint (SUR): Bone mineral density
Study 22739977 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22739977 — Surrogate Endpoint (SUR): Blood pressure
Study 11535506 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11535506 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11535506 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 30606784 — Surrogate Endpoint (SUR): Bone mineral density
Study 15710002 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9706928 — Surrogate Endpoint (SUR): Blood pressure
Study 19164318 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11557167 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11557167 — Surrogate Endpoint (SUR): Blood pressure
Study 27571927 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27571927 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 11788429 — Surrogate Endpoint (SUR): Blood pressure
Study 31136052 — Monitoring Biomarker (MOI): HBV DNA
Study 10726721 — Surrogate Endpoint (SUR): Blood pressure
Study 10726721 — Surrogate Endpoint (SUR): Serum uric acid
Study 24887686 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10093144 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 10093144 — Surrogate Endpoint (SUR): Blood pressure
Study 7487212 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 7487212 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 31030606 — Surrogate Endpoint (SUR): Blood pressure
Study 27518661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19463349 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 15770240 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 31987407 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 31987407 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31987407 — Predictive Biomarker (PRD): Hormone receptor
Study 26471830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11843951 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29016549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29016549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18435772 — Surrogate Endpoint (SUR): Blood pressure
Study 12584834 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 12584834 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10511060 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1785379 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 7059418 — Surrogate Endpoint (SUR): Blood pressure
Study 31664428 — Surrogate Endpoint (SUR): Blood pressure
Study 22435514 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 22435514 — Surrogate Endpoint (SUR): Blood pressure
Study 31733631 — Surrogate Endpoint (SUR): Blood pressure
Study 31733631 — Safety Biomarker (SAF): BDNF
Study 21715702 — Safety Biomarker (SAF): DRD3
Study 26630719 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 26630719 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 8119068 — Surrogate Endpoint (SUR): Blood pressure
Study 2851626 — Surrogate Endpoint (SUR): Blood pressure
Study 18096708 — Monitoring Biomarker (MOI): Procalcitonin
Study 11966500 — Surrogate Endpoint (SUR): Bone mineral density
Study 9673745 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9673745 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8083103 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29776437 — Surrogate Endpoint (SUR): Serum creatinine
Study 19287109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19287109 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18160462 — Surrogate Endpoint (SUR): Bone mineral density
Study 11994904 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6153233 — Surrogate Endpoint (SUR): Blood pressure
Study 31841646 — Predictive Biomarker (PRD): OSR1 mRNA
Genes: OSR1; ODD
Study 29040891 — Surrogate Endpoint (SUR): Blood pressure
Study 23724544 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 20950383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2