TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1712206 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 2871818 — Surrogate Endpoint (SUR): Blood pressure
Study 26719492 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10950051 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20880642 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 2474109 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2474109 — Surrogate Endpoint (SUR): Blood pressure
Study 19745175 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26910108 — Safety Biomarker (SAF): DRD2
Study 25135744 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 28826727 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26764322 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 15514725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2805771 — Surrogate Endpoint (SUR): Blood pressure
Study 1103708 — Surrogate Endpoint (SUR): Blood pressure
Study 21825259 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16700816 — Surrogate Endpoint (SUR): Blood pressure
Study 31732485 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10671664 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 9174182 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 8642235 — Surrogate Endpoint (SUR): Blood pressure
Study 6375329 — Surrogate Endpoint (SUR): Blood pressure
Study 22901557 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24372304 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 24372304 — Surrogate Endpoint (SUR): Blood pressure
Study 16125536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16125536 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16125536 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7496561 — Surrogate Endpoint (SUR): Blood pressure
Study 21488802 — Safety Biomarker (SAF): Interleukin 1
Study 21488802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6209506 — Surrogate Endpoint (SUR): Blood pressure
Study 22071199 — Surrogate Endpoint (SUR): Blood pressure
Study 18563969 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16018851 — Surrogate Endpoint (SUR): Blood pressure
Study 10335764 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10335764 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27895542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27895542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12037657 — Surrogate Endpoint (SUR): Blood pressure
Study 25772548 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11696916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11967825 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29748907 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29748907 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 29748907 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 29748907 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 24670828 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 12127382 — Surrogate Endpoint (SUR): Blood pressure
Study 9667590 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 9667590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9667590 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30508156 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30508156 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30508156 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30508156 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30508156 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 17109685 — Monitoring Biomarker (MOI): HBV DNA
Study 12915289 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 8776187 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 8776187 — Predictive Biomarker (PRD): NELFCD mRNA
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 27491533 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 26591355 — Surrogate Endpoint (SUR): Serum creatinine
Study 20506254 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 9243044 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19933822 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 24063860 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9301442 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8359098 — Surrogate Endpoint (SUR): Blood pressure
Study 23725851 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23725851 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23725851 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 23725851 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 19040589 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19040589 — Surrogate Endpoint (SUR): Blood pressure
Study 21974764 — Surrogate Endpoint (SUR): Blood pressure
Study 11867177 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 9517989 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14595471 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 1680135 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1680135 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1680135 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15552533 — Surrogate Endpoint (SUR): Blood pressure
Study 11208882 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 11208882 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 12482798 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30049849 — Surrogate Endpoint (SUR): Total kidney volume
Study 2340539 — Surrogate Endpoint (SUR): Serum sodium
Study 2340539 — Surrogate Endpoint (SUR): Serum potassium
Study 7282615 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 22568178 — Surrogate Endpoint (SUR): Blood pressure
Study 10102254 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10102254 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22155531 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 9360028 — Surrogate Endpoint (SUR): Blood pressure
Study 3009050 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12937228 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12937228 — Surrogate Endpoint (SUR): Blood pressure
Study 12937228 — Surrogate Endpoint (SUR): Serum creatinine
Study 12937228 — Surrogate Endpoint (SUR): Serum potassium
Study 27755159 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 27755159 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 24148194 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 20542963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19288904 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17054466 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 12576315 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12576315 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7933324 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 3064604 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29520889 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29520889 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2204432 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 31812472 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 21812357 — Surrogate Endpoint (SUR): Serum calcium
Study 19376184 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 16434589 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 6336600 — Surrogate Endpoint (SUR): Blood pressure
Study 6336600 — Surrogate Endpoint (SUR): Serum uric acid
Study 6336600 — Surrogate Endpoint (SUR): Serum potassium
Study 29467885 — Predictive Biomarker (PRD): NDP mRNA
Genes: NDP; EVR2
Study 17171884 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29581202 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 18178097 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18178097 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18178097 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 18178097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12640085 — Surrogate Endpoint (SUR): Blood pressure
Study 28169885 — Surrogate Endpoint (SUR): Blood pressure
Study 17578859 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17578859 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17578859 — Surrogate Endpoint (SUR): Serum calcium
Study 24498399 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18219959 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11940545 — Surrogate Endpoint (SUR): Blood pressure
Study 2693918 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2693918 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25627186 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 30967597 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 30967597 — Predictive Biomarker (PRD): UGT2B17 mRNA
Genes: UGT2B17
Study 30967597 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28697504 — Predictive Biomarker (PRD): PLXNB1 mRNA
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 23627832 — Surrogate Endpoint (SUR): Blood pressure
Study 1694945 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1694945 — Surrogate Endpoint (SUR): Blood pressure
Study 41475 — Surrogate Endpoint (SUR): Blood pressure
Study 23870127 — Predictive Biomarker (PRD): GPSM2 mRNA
Genes: GPSM2; LGN
Study 22613099 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 12787319 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 10918646 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8872727 — Surrogate Endpoint (SUR): Blood pressure
Study 31479116 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 8092094 — Surrogate Endpoint (SUR): Blood pressure
Study 21412424 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19110158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17227995 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9736420 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 7914888 — Surrogate Endpoint (SUR): Blood pressure
Study 779390 — Surrogate Endpoint (SUR): Serum potassium
Study 31981777 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18037776 — Surrogate Endpoint (SUR): Blood pressure
Study 18037776 — Surrogate Endpoint (SUR): Serum potassium
Study 18037776 — Surrogate Endpoint (SUR): Serum uric acid
Study 16116345 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16116345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16116345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8731513 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8731513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8731513 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8731513 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24187901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17934663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12191747 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19638366 — Surrogate Endpoint (SUR): Blood pressure
Study 12469001 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 9469353 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7879258 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 361794 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20870099 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 17320962 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23443254 — Surrogate Endpoint (SUR): Bone mineral density
Study 23443254 — Predictive Biomarker (PRD): Hormone receptor
Study 29973170 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 24622715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26377300 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 25073431 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25073431 — Safety Biomarker (SAF): BDNF
Study 17513402 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 3108930 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 24513614 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24513614 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24513614 — Surrogate Endpoint (SUR): Blood pressure
Study 20736149 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 20736149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1283584 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23922479 — Surrogate Endpoint (SUR): Blood pressure
Study 10957689 — Surrogate Endpoint (SUR): Blood pressure
Study 7499063 — Surrogate Endpoint (SUR): Blood pressure
Study 10435066 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28935273 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 24846279 — Safety Biomarker (SAF): Type I cytoskeletal 18 Keratin
Genes: KRT18; CYK18; PIG46
Study 19543499 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17292595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8477016 — Surrogate Endpoint (SUR): Blood pressure
Study 22271776 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 19337555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19337555 — Surrogate Endpoint (SUR): Blood pressure
Study 19337555 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19337555 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7011348 — Surrogate Endpoint (SUR): Blood pressure
Study 25414152 — Surrogate Endpoint (SUR): Blood pressure
Study 17972425 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10326538 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2654576 — Surrogate Endpoint (SUR): Blood pressure
Study 30620727 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 30620727 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30620727 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 30620727 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 30620727 — Surrogate Endpoint (SUR): Bone mineral density
Study 8192551 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 21242556 — Surrogate Endpoint (SUR): Blood pressure
Study 21242556 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18065809 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18065809 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 18065809 — Surrogate Endpoint (SUR): Blood pressure
Study 10971238 — Surrogate Endpoint (SUR): Blood pressure
Study 1310922 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 30106185 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 17649769 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 29683921 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 28686823 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23199095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23199095 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1565267 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1329159 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29059600 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24693953 — Surrogate Endpoint (SUR): Blood pressure
Study 24693953 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7695978 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7464561 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24382002 — Surrogate Endpoint (SUR): Bone mineral density
Study 21881869 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 21881869 — Predictive Biomarker (PRD): OPN1SW mRNA
Genes: OPN1SW; BCP
Study 17434635 — Surrogate Endpoint (SUR): Blood pressure
Study 11869844 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 1713882 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 26068513 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 20484173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14601012 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 31761946 — Surrogate Endpoint (SUR): Blood pressure
Study 24189212 — Surrogate Endpoint (SUR): Blood pressure
Study 2229452 — Surrogate Endpoint (SUR): Blood pressure
Study 9951570 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 378754 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 378754 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31533777 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31533777 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31533777 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31533777 — Predictive Biomarker (PRD): Hormone receptor
Study 22502772 — Surrogate Endpoint (SUR): Blood pressure
Study 9007781 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29365333 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 29365333 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29365333 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 20880055 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 20880055 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 14523307 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 3534005 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31900486 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31241441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31241441 — Surrogate Endpoint (SUR): Serum calcium
Study 16556147 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16556147 — Surrogate Endpoint (SUR): Blood pressure
Study 24146363 — Surrogate Endpoint (SUR): Blood pressure
Study 9931687 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9931687 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9931687 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21732894 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19628666 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19628666 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15220769 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 25850865 — Surrogate Endpoint (SUR): Serum creatinine
Study 22192068 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22192068 — Surrogate Endpoint (SUR): Blood pressure
Study 10571698 — Surrogate Endpoint (SUR): Bone mineral density
Study 28326569 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 23434908 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 14980903 — Surrogate Endpoint (SUR): Blood pressure
Study 3900181 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 3900181 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8862476 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 8862476 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 1675867 — Surrogate Endpoint (SUR): Blood pressure