TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11956673 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10066994 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 7726447 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11197251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10920943 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10920943 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23468338 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21518005 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21518005 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21518005 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 18505369 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 6377610 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 6377610 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 2540099 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 31967501 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 20429800 — Surrogate Endpoint (SUR): Blood pressure
Study 7552591 — Surrogate Endpoint (SUR): Blood pressure
Study 25853384 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 9776411 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9776411 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9776411 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2904755 — Surrogate Endpoint (SUR): Blood pressure
Study 24847084 — Surrogate Endpoint (SUR): Blood pressure
Study 11855313 — Surrogate Endpoint (SUR): Blood pressure
Study 2240628 — Surrogate Endpoint (SUR): Blood pressure
Study 19224764 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11144048 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 27470620 — Monitoring Biomarker (MOI): HBV DNA
Study 24813065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15685511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15685511 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15364166 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1703611 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22028418 — Surrogate Endpoint (SUR): Blood pressure
Study 22028418 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11133595 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11133595 — Surrogate Endpoint (SUR): Blood pressure
Study 28202842 — Surrogate Endpoint (SUR): Blood pressure
Study 24861098 — Surrogate Endpoint (SUR): Blood pressure
Study 10474124 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 8556398 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6614421 — Surrogate Endpoint (SUR): Blood pressure
Study 29514235 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22252909 — Surrogate Endpoint (SUR): Blood pressure
Study 20497980 — Surrogate Endpoint (SUR): Blood pressure
Study 1691357 — Surrogate Endpoint (SUR): Blood pressure
Study 15140756 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 15140756 — Surrogate Endpoint (SUR): Serum calcium
Study 9094727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 2031258 — Surrogate Endpoint (SUR): Serum creatinine
Study 24868098 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19282274 — Surrogate Endpoint (SUR): Blood pressure
Study 12373472 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 11833047 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24503762 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 16239128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12483453 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12483453 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 12483453 — Surrogate Endpoint (SUR): Blood pressure
Study 7564084 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 7564084 — Surrogate Endpoint (SUR): Blood pressure
Study 17595415 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15964291 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 26026638 — Surrogate Endpoint (SUR): Serum creatinine
Study 22918704 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 22918704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22918704 — Surrogate Endpoint (SUR): Bone mineral density
Study 25801797 — Surrogate Endpoint (SUR): Bone mineral density
Study 23801602 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 16830214 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 16830214 — Predictive Biomarker (PRD): TERF1 mRNA
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study 16830214 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19181414 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 8560679 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 17973175 — Surrogate Endpoint (SUR): Blood pressure
Study 28653583 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 25850089 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 20136757 — Surrogate Endpoint (SUR): Blood pressure
Study 2010305 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23754631 — Surrogate Endpoint (SUR): Blood pressure
Study 23754631 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23754631 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23405800 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 16202854 — Surrogate Endpoint (SUR): Blood pressure
Study 7498988 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7498988 — Surrogate Endpoint (SUR): Blood pressure
Study 11834137 — Surrogate Endpoint (SUR): Blood pressure
Study 31252032 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 16893989 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10821361 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1467375 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 1467375 — Surrogate Endpoint (SUR): Blood pressure
Study 30808080 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 20601209 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10740139 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8934356 — Surrogate Endpoint (SUR): Blood pressure
Study 31509331 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 31151481 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 17405898 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 17405898 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9870344 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7986439 — Predictive Biomarker (PRD): CLYBL mRNA
Genes: CLYBL; CLB
Study 7986439 — Predictive Biomarker (PRD): FAM53B mRNA
Genes: FAM53B; KIAA0140; SMP
Study 2537566 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2537566 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25904733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25904733 — Surrogate Endpoint (SUR): Blood pressure
Study 25904733 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19493352 — Monitoring Biomarker (MOI): Procalcitonin
Study 16786535 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16786535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16786535 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11091247 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 20966393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18843828 — Surrogate Endpoint (SUR): Blood pressure
Study 15741815 — Surrogate Endpoint (SUR): Blood pressure
Study 11759128 — Surrogate Endpoint (SUR): Blood pressure
Study 6356897 — Surrogate Endpoint (SUR): Blood pressure
Study 10092007 — Predictive Biomarker (PRD): PRF1
Genes: PFP; P1; HPLH2
Study 7768584 — Surrogate Endpoint (SUR): Blood pressure
Study 7768584 — Surrogate Endpoint (SUR): Serum creatinine
Study 31291417 — Surrogate Endpoint (SUR): Blood pressure
Study 11997821 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27917845 — Surrogate Endpoint (SUR): Blood pressure
Study 16538534 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1281043 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 22920718 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 3277569 — Surrogate Endpoint (SUR): Blood pressure
Study 3277569 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19667499 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 31295003 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 31295003 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29926300 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 20514787 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 18584251 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 15921958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15921958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7734231 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 8123866 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 4006145 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 22822019 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20929127 — Predictive Biomarker (PRD): GNLY mRNA
Genes: GNLY; LAG2; NKG5; TLA519
Study 20929127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20929127 — Monitoring Biomarker (MOI): HBV DNA
Study 20929127 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16142016 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16142016 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11905957 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29663320 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 8792380 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 17652834 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17652834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12422105 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10600289 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 6215443 — Surrogate Endpoint (SUR): Blood pressure
Study 25244777 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 22307494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12798824 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12798824 — Surrogate Endpoint (SUR): Blood pressure
Study 11420773 — Surrogate Endpoint (SUR): Bone mineral density
Study 31864157 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 15023878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9286464 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9286464 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24845963 — Surrogate Endpoint (SUR): Blood pressure
Study 11432696 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 11432696 — Predictive Biomarker (PRD): TRIM32 mRNA
Genes: TRIM32; HT2A
Study 7949021 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25131305 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25131305 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25131305 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18978624 — Surrogate Endpoint (SUR): Bone mineral density
Study 20518950 — Surrogate Endpoint (SUR): Blood pressure
Study 20518950 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18090405 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6427057 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24850754 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 22133305 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17496463 — Surrogate Endpoint (SUR): Blood pressure
Study 17496463 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11783681 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11783681 — Surrogate Endpoint (SUR): Blood pressure
Study 31242517 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 23456778 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16469989 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 10686210 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 9139617 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1536625 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 1536625 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6388305 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24050577 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24050577 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11753809 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 9289303 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2879969 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21540740 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 18438830 — Surrogate Endpoint (SUR): Bone mineral density
Study 16284225 — Surrogate Endpoint (SUR): Blood pressure
Study 14519177 — Surrogate Endpoint (SUR): Blood pressure
Study 9185029 — Surrogate Endpoint (SUR): Blood pressure
Study 30354579 — Surrogate Endpoint (SUR): Blood pressure
Study 27433887 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16045185 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 9843458 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 19185772 — Surrogate Endpoint (SUR): Blood pressure
Study 15200448 — Surrogate Endpoint (SUR): Blood pressure
Study 31900231 — Surrogate Endpoint (SUR): Blood pressure
Study 15030297 — Surrogate Endpoint (SUR): Blood pressure
Study 15030297 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30887844 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19890250 — Surrogate Endpoint (SUR): Blood pressure
Study 18327510 — Surrogate Endpoint (SUR): Blood pressure
Study 11394391 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 2500068 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 28708072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24089379 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 21777745 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 17505029 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15452837 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15452837 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9669262 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23527561 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23527561 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15700744 — Safety Biomarker (SAF): Hyaluronic acid
Study 1312769 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 1312769 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 2029499 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2029499 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22810046 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 17103169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15188945 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23733668 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12948063 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1857725 — Surrogate Endpoint (SUR): Blood pressure
Study 26755682 — Surrogate Endpoint (SUR): Blood pressure
Study 23529834 — Predictive Biomarker (PRD): DRG2 mRNA
Genes: DRG2
Study 21739267 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 21739267 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19125322 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 7638127 — Surrogate Endpoint (SUR): Blood pressure
Study 21854192 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 16476042 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 16476042 — Surrogate Endpoint (SUR): Bone mineral density
Study 29808711 — Surrogate Endpoint (SUR): Blood pressure
Study 23996482 — Surrogate Endpoint (SUR): Serum creatinine
Study 12009014 — Surrogate Endpoint (SUR): Bone mineral density
Study 2110411 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 24988118 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21777268 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16937604 — Surrogate Endpoint (SUR): Blood pressure
Study 23163146 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23163146 — Surrogate Endpoint (SUR): Blood pressure
Study 17051504 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29414272 — Surrogate Endpoint (SUR): Blood pressure
Study 23134222 — Predictive Biomarker (PRD): TNS3 mRNA
Genes: TNS3; TEM6; TENS1; TPP
Study 20130603 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20130603 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 16706649 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12830461 — Surrogate Endpoint (SUR): Serum calcium
Study 28780512 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 28780512 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11046202 — Surrogate Endpoint (SUR): Serum sodium
Study 11046202 — Surrogate Endpoint (SUR): Serum potassium
Study 8375360 — Surrogate Endpoint (SUR): Blood pressure
Study 25581217 — Surrogate Endpoint (SUR): Bone mineral density
Study 17135810 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 12071899 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 19234828 — Surrogate Endpoint (SUR): Blood pressure
Study 7995781 — Surrogate Endpoint (SUR): Blood pressure
Study 22132809 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12834519 — Surrogate Endpoint (SUR): Bone mineral density
Study 31427751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31427751 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31427751 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 20584263 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 28779269 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 27129315 — Surrogate Endpoint (SUR): Blood pressure
Study 24367008 — Surrogate Endpoint (SUR): Serum creatinine
Study 11887047 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 11887047 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10094221 — Safety Biomarker (SAF): Th2 cell
Study 27267403 — Predictive Biomarker (PRD): RIGI mRNA
Genes: RIGI; DDX58
Study 24512527 — Surrogate Endpoint (SUR): Bone mineral density
Study 15663545 — Safety Biomarker (SAF): Interleukin 1
Study 15663545 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 2523870 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2523870 — Surrogate Endpoint (SUR): Serum creatinine
Study 31069457 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30481720 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 27743855 — Surrogate Endpoint (SUR): Blood pressure
Study 26907087 — Surrogate Endpoint (SUR): Serum creatinine
Study 11804984 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11804984 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27475283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27475283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26202179 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19651272 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 19651272 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9630000 — Safety Biomarker (SAF): DRD2
Study 10836913 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8770972 — Surrogate Endpoint (SUR): Serum calcium
Study 28985109 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 7003391 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein