TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17413099 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 10195235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30614013 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23275453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19778663 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 11256875 — Surrogate Endpoint (SUR): Bone mineral density
Study 29092982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29092982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21331773 — Surrogate Endpoint (SUR): Serum creatinine
Study 11061604 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 31300951 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 31219248 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25873097 — Surrogate Endpoint (SUR): Blood pressure
Study 21114549 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21114549 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11036120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8412414 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 20205482 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 15889312 — Surrogate Endpoint (SUR): Bone mineral density
Study 8558208 — Surrogate Endpoint (SUR): Serum calcium
Study 1757027 — Safety Biomarker (SAF): Hyaluronic acid
Study 30982776 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 27087080 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27087080 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22422593 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 12378376 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12378376 — Surrogate Endpoint (SUR): Blood pressure
Study 31754239 — Surrogate Endpoint (SUR): Serum uric acid
Study 31754239 — Surrogate Endpoint (SUR): Blood pressure
Study 31754239 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25496000 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23407049 — Safety Biomarker (SAF): MTHFR
Study 19820812 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30239290 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 29629400 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 10614716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1930849 — Surrogate Endpoint (SUR): Blood pressure
Study 1930849 — Surrogate Endpoint (SUR): Serum potassium
Study 9869503 — Surrogate Endpoint (SUR): Blood pressure
Study 9869503 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21296780 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21296780 — Surrogate Endpoint (SUR): Blood pressure
Study 7743570 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28376768 — Surrogate Endpoint (SUR): Bone mineral density
Study 16034276 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 8085776 — Surrogate Endpoint (SUR): Blood pressure
Study 30511840 — Surrogate Endpoint (SUR): Blood pressure
Study 26447153 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 23359034 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 23359034 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 19411747 — Surrogate Endpoint (SUR): Blood pressure
Study 24006673 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25329159 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 25329159 — Predictive Biomarker (PRD): ELOVL5 mRNA
Genes: ELOVL5; ELOVL2; PRO0530
Study 24767423 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 26250486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9329359 — Surrogate Endpoint (SUR): Blood pressure
Study 20673995 — Surrogate Endpoint (SUR): Blood pressure
Study 10847232 — Surrogate Endpoint (SUR): Blood pressure
Study 31177999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31177999 — Surrogate Endpoint (SUR): Blood pressure
Study 25896121 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 20103314 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15961531 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12165184 — Surrogate Endpoint (SUR): Blood pressure
Study 31689951 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19567515 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15969668 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 2283646 — Surrogate Endpoint (SUR): Blood pressure
Study 19020533 — Surrogate Endpoint (SUR): Blood pressure
Study 19020533 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27493198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15482599 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 12014386 — Surrogate Endpoint (SUR): Serum creatinine
Study 12643118 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 29408562 — Surrogate Endpoint (SUR): Blood pressure
Study 27033026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27033026 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23225089 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 10857934 — Surrogate Endpoint (SUR): Blood pressure
Study 7931189 — Monitoring Biomarker (MOI): HBV DNA
Study 3290578 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 3290578 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 31734452 — Surrogate Endpoint (SUR): Bone mineral density
Study 16076733 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 12074764 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 20131073 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 31941539 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 16332650 — Surrogate Endpoint (SUR): Blood pressure
Study 12389003 — Surrogate Endpoint (SUR): Blood pressure
Study 9665096 — Surrogate Endpoint (SUR): Blood pressure
Study 28929816 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19465485 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 10950441 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10216806 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10216806 — Surrogate Endpoint (SUR): Blood pressure
Study 19661193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15918296 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12816681 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11783172 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 29145308 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 18853093 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10099042 — Surrogate Endpoint (SUR): Blood pressure
Study 2667525 — Surrogate Endpoint (SUR): Serum potassium
Study 2667525 — Surrogate Endpoint (SUR): Serum sodium
Study 10842262 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 10842262 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21955475 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21955475 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21955475 — Surrogate Endpoint (SUR): Blood pressure
Study 11705307 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29432650 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 12515745 — Surrogate Endpoint (SUR): Blood pressure
Study 8880557 — Surrogate Endpoint (SUR): Blood pressure
Study 22842994 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20542512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20542512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9286467 — Surrogate Endpoint (SUR): Blood pressure
Study 9286467 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8416077 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25412862 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 18560218 — Surrogate Endpoint (SUR): Blood pressure
Study 15836828 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15836828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15836828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15836828 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15836828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15836828 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10084094 — Surrogate Endpoint (SUR): Blood pressure
Study 29367439 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27928077 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22781526 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20234330 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 31306043 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31306043 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31306043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28448655 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28448655 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26210387 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21859655 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21859655 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9933852 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30876831 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26591005 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16227145 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12105241 — Surrogate Endpoint (SUR): Serum creatinine
Study 21610364 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27824680 — Surrogate Endpoint (SUR): Blood pressure
Study 2568202 — Surrogate Endpoint (SUR): Blood pressure
Study 25065959 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 23062105 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21996202 — Surrogate Endpoint (SUR): Blood pressure
Study 21996202 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21996202 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10428734 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10428734 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11914748 — Surrogate Endpoint (SUR): Blood pressure
Study 2137279 — Surrogate Endpoint (SUR): Blood pressure
Study 29698983 — Safety Biomarker (SAF): miR-133a
Study 24505281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24505281 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31468473 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 31468473 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31468473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31290996 — Predictive Biomarker (PRD): LYN mRNA
Genes: LYN; JTK8
Study 19303940 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 19303940 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19303940 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 15179345 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16397311 — Surrogate Endpoint (SUR): Blood pressure
Study 21654266 — Surrogate Endpoint (SUR): Serum uric acid
Study 16356696 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 8733686 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8733686 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9137901 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9137901 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7982251 — Surrogate Endpoint (SUR): Blood pressure
Study 23264399 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23264399 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24408120 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 24408120 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17270510 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 11829199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7531327 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 25697830 — Surrogate Endpoint (SUR): Blood pressure
Study 15893402 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26730967 — Surrogate Endpoint (SUR): Bacterial count
Study 19848045 — Surrogate Endpoint (SUR): Blood pressure
Study 11923038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11923038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11923038 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11923038 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9577931 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9577931 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 26527777 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study 26527777 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH
Study 26527777 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19451556 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19451556 — Surrogate Endpoint (SUR): Serum creatinine
Study 2272864 — Surrogate Endpoint (SUR): Blood pressure
Study 30760655 — Surrogate Endpoint (SUR): Blood pressure
Study 27588209 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27588209 — Surrogate Endpoint (SUR): Blood pressure
Study 15611537 — Surrogate Endpoint (SUR): Blood pressure
Study 9658759 — Monitoring Biomarker (MOI): HBV DNA
Study 7641721 — Surrogate Endpoint (SUR): Blood pressure
Study 25749740 — Surrogate Endpoint (SUR): Bone mineral density
Study 25092484 — Surrogate Endpoint (SUR): Blood pressure
Study 15155330 — Surrogate Endpoint (SUR): Blood pressure
Study 18607381 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15647641 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10442492 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 10442492 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 19731119 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11045137 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8958387 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 30463820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27312903 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27312903 — Surrogate Endpoint (SUR): Blood pressure
Study 19773416 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 19773416 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19773416 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 19773416 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 19773416 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 19773416 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 19773416 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19773416 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 19773416 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 27442314 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 14729722 — Surrogate Endpoint (SUR): Blood pressure
Study 24171260 — Surrogate Endpoint (SUR): Blood pressure
Study 19369186 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 9469323 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11799261 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25268370 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25268370 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25268370 — Predictive Biomarker (PRD): Hormone receptor
Study 12375715 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10980831 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8850385 — Surrogate Endpoint (SUR): Blood pressure
Study 26723854 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 7840721 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23276660 — Surrogate Endpoint (SUR): Blood pressure
Study 16569537 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24215127 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24215127 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19756418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19756418 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12901530 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12901530 — Surrogate Endpoint (SUR): Blood pressure
Study 27981279 — Safety Biomarker (SAF): Hyaluronic acid
Study 22734375 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 18242485 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 31784929 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31784929 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31784929 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23300117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23300117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22386826 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 2704576 — Surrogate Endpoint (SUR): Blood pressure
Study 30671591 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27155753 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 367410 — Surrogate Endpoint (SUR): Blood pressure
Study 30859382 — Safety Biomarker (SAF): Interleukin 1
Study 30859382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30859382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30859382 — Surrogate Endpoint (SUR): Blood pressure
Study 2985658 — Surrogate Endpoint (SUR): Blood pressure
Study 26943871 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22983924 — Surrogate Endpoint (SUR): Blood pressure
Study 17882542 — Surrogate Endpoint (SUR): Blood pressure
Study 15036550 — Surrogate Endpoint (SUR): Blood pressure
Study 363333 — Surrogate Endpoint (SUR): Blood pressure
Study 363333 — Surrogate Endpoint (SUR): Serum potassium
Study 22001172 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22001172 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12577356 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19329193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19329193 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19329193 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 16886837 — Predictive Biomarker (PRD): TRIM32 mRNA
Genes: TRIM32; HT2A
Study 11740299 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30682452 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study 30682452 — Predictive Biomarker (PRD): CPA3 mRNA
Genes: CPA3
Study 30682452 — Predictive Biomarker (PRD): DNASE1L3 mRNA
Genes: DNASE1L3; DHP2; DNAS1L3
Study 30682452 — Predictive Biomarker (PRD): ALPL mRNA
Genes: ALPL
Study 30682452 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 30682452 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 30682452 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21968012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21968012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21968012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17408017 — Predictive Biomarker (PRD): CS mRNA
Genes: CS