TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31775412 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31775412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30009735 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 2896401 — Surrogate Endpoint (SUR): Blood pressure
Study 26194361 — Predictive Biomarker (PRD): ATP7B mRNA
Genes: ATP7B; PWD; WC1; WND
Study 26194361 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 26194361 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23855560 — Surrogate Endpoint (SUR): Serum sodium
Study 8860712 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24013574 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 1306815 — Surrogate Endpoint (SUR): Blood pressure
Study 31213079 — Surrogate Endpoint (SUR): Blood pressure
Study 29767684 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27321324 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27321324 — Surrogate Endpoint (SUR): Blood pressure
Study 22665124 — Surrogate Endpoint (SUR): Blood pressure
Study 20447572 — Surrogate Endpoint (SUR): Blood pressure
Study 31674861 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 24214217 — Predictive Biomarker (PRD): UGT2B15 mRNA
Genes: UGT2B15; UGT2B8
Study 16282930 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 10192613 — Monitoring Biomarker (MOI): HBV DNA
Study 8001393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1700873 — Surrogate Endpoint (SUR): Serum sodium
Study 7019638 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 7019638 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 28576736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28576736 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study 25082923 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 9554807 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 9554807 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9554807 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9554807 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9554807 — Surrogate Endpoint (SUR): Blood pressure
Study 25657022 — Surrogate Endpoint (SUR): Blood pressure
Study 21602759 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9065993 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9065993 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9065993 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8457132 — Surrogate Endpoint (SUR): Serum uric acid
Study 8457132 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 26400520 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23705925 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17276668 — Surrogate Endpoint (SUR): Blood pressure
Study 12213858 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12213858 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 13418 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 13418 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 13418 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 23936304 — Monitoring Biomarker (MOI): Procalcitonin
Study 23672753 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23672753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23672753 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19855285 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14763994 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 14763994 — Surrogate Endpoint (SUR): Serum testosterone
Study 7943386 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 28225483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28225483 — Surrogate Endpoint (SUR): Blood pressure
Study 28225483 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23086750 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 23086750 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 23086750 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 16413010 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 14652518 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 30944249 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26817117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26817117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23021631 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23021631 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21248759 — Surrogate Endpoint (SUR): Blood pressure
Study 18276852 — Predictive Biomarker (PRD): TACR1 mRNA
Genes: TACR1; NK1R; TAC1R
Study 16982493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16982493 — Monitoring Biomarker (MOI): Procalcitonin
Study 11088095 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11088095 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1541032 — Surrogate Endpoint (SUR): Blood pressure
Study 25398137 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9432685 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 1312773 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30741865 — Predictive Biomarker (PRD): NINL mRNA
Genes: NINL; KIAA0980; NLP
Study 30953549 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18181974 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 31823753 — Surrogate Endpoint (SUR): Blood pressure
Study 24525257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22748484 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 22748484 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2266340 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2266340 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11011813 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 1727093 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29024499 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 26950082 — Surrogate Endpoint (SUR): Blood pressure
Study 24612659 — Surrogate Endpoint (SUR): Blood pressure
Study 20398559 — Surrogate Endpoint (SUR): Blood pressure
Study 23631443 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 19205723 — Surrogate Endpoint (SUR): Blood pressure
Study 17284576 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 12823645 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12823645 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 8585003 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 22555112 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22555112 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20395648 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 16177676 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16177676 — Surrogate Endpoint (SUR): Blood pressure
Study 7768585 — Surrogate Endpoint (SUR): Blood pressure
Study 17096305 — Surrogate Endpoint (SUR): Blood pressure
Study 9193008 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26519020 — Surrogate Endpoint (SUR): Blood pressure
Study 24004475 — Surrogate Endpoint (SUR): Blood pressure
Study 24004475 — Surrogate Endpoint (SUR): Serum creatinine
Study 12854176 — Safety Biomarker (SAF): Hyaluronic acid
Study 29027715 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 20093623 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 20093623 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20093623 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 20093623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18565159 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 28860165 — Predictive Biomarker (PRD): SLC38A2 mRNA
Genes: SLC38A2; ATA2; KIAA1382; SAT2; SNAT2
Study 28860165 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 31143777 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study 16709697 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16709697 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16709697 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15290418 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15290418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15290418 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11250190 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8988994 — Surrogate Endpoint (SUR): Blood pressure
Study 2364464 — Monitoring Biomarker (MOI): HBV DNA
Study 20192884 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 10203379 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 10203379 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10203379 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23429588 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23429588 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17320023 — Surrogate Endpoint (SUR): Bone mineral density
Study 1401761 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2416164 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 25014007 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 25014007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25014007 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10994627 — Surrogate Endpoint (SUR): Serum creatinine
Study 29224127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24395436 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 9013270 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27173230 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 27173230 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 1978963 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 6794365 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 10669337 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30371182 — Surrogate Endpoint (SUR): Blood pressure
Study 17533394 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2961787 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25673113 — Surrogate Endpoint (SUR): Blood pressure
Study 21395644 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16945613 — Surrogate Endpoint (SUR): Bone mineral density
Study 16945613 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27461803 — Surrogate Endpoint (SUR): Blood pressure
Study 2734422 — Surrogate Endpoint (SUR): Blood pressure
Study 25328957 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 18085502 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 14598874 — Surrogate Endpoint (SUR): Blood pressure
Study 31602579 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25041859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22241056 — Predictive Biomarker (PRD): CPT1A mRNA
Genes: CPT1A; CPT1
Study 22241056 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 15145810 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 31525187 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21266950 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 21266950 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31806605 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 23433349 — Surrogate Endpoint (SUR): Blood pressure
Study 21812663 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 21812663 — Safety Biomarker (SAF): Th2 cell
Study 19627292 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 11707629 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 24920884 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24920884 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22383318 — Surrogate Endpoint (SUR): Bone mineral density
Study 20502447 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15191507 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31773776 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 28076735 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 21613350 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 21613350 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 9140907 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18249220 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18249220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18249220 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11401114 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31969168 — Surrogate Endpoint (SUR): Blood pressure
Study 16937281 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11828945 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3033389 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3033389 — Surrogate Endpoint (SUR): Blood pressure
Study 22581278 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 18575157 — Surrogate Endpoint (SUR): Bone mineral density
Study 9848888 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9848888 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22071384 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15578195 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 6365107 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6365107 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29340488 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24074360 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 21663597 — Surrogate Endpoint (SUR): Blood pressure
Study 19373239 — Surrogate Endpoint (SUR): Blood pressure
Study 28256406 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19687610 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8438781 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30993587 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 28042070 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28042070 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12915959 — Surrogate Endpoint (SUR): Bone mineral density
Study 25532501 — Monitoring Biomarker (MOI): HBV DNA
Study 25532501 — Surrogate Endpoint (SUR): Serum creatinine
Study 25532501 — Surrogate Endpoint (SUR): Bone mineral density
Study 29410046 — Predictive Biomarker (PRD): NIBAN1 mRNA
Genes: NIBAN1; C1orf24; FAM129A; NIBAN; GIG39
Study 23104251 — Predictive Biomarker (PRD): CXCL16 mRNA
Genes: CXCL16; SCYB16; SRPSOX; UNQ2759/PRO6714
Study 23104251 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 23104251 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11912265 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 18472682 — Surrogate Endpoint (SUR): Blood pressure
Study 12873958 — Surrogate Endpoint (SUR): Blood pressure
Study 8917260 — Surrogate Endpoint (SUR): Bone mineral density
Study 29466116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29466116 — Surrogate Endpoint (SUR): Blood pressure
Study 29466116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29466116 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22383993 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 11880968 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7477806 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 24973230 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 21455059 — Surrogate Endpoint (SUR): Blood pressure
Study 16757527 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 15313211 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 28003251 — Surrogate Endpoint (SUR): Blood pressure
Study 11468761 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 2843031 — Surrogate Endpoint (SUR): Blood pressure
Study 27774990 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 23435671 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19321570 — Surrogate Endpoint (SUR): Bone mineral density
Study 16296368 — Surrogate Endpoint (SUR): Blood pressure
Study 11912566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9567633 — Surrogate Endpoint (SUR): Blood pressure
Study 14982610 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14982610 — Surrogate Endpoint (SUR): Blood pressure
Study 23246796 — Safety Biomarker (SAF): Reactive oxygen species
Study 18822021 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9360530 — Surrogate Endpoint (SUR): Serum testosterone
Study 27512103 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22008443 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 18055072 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9183496 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29283975 — Surrogate Endpoint (SUR): Blood pressure
Study 21364957 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15324521 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15324521 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11208239 — Surrogate Endpoint (SUR): Blood pressure
Study 7826297 — Surrogate Endpoint (SUR): Blood pressure
Study 23808433 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 21605236 — Safety Biomarker (SAF): Hyaluronic acid
Study 19372172 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 15337017 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 11343523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9552776 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 28775061 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28775061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25532068 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31855207 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 22903545 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study 22903545 — Predictive Biomarker (PRD): TNFRSF14 mRNA
Genes: TNFRSF14; HVEA; HVEM; UNQ329/PRO509
Study 16506060 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16506060 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 16506060 — Predictive Biomarker (PRD): CD53 mRNA
Genes: CD53; MOX44; TSPAN25
Study 16506060 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23161092 — Surrogate Endpoint (SUR): Blood pressure
Study 518220 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 518220 — Surrogate Endpoint (SUR): Blood pressure
Study 2012448 — Surrogate Endpoint (SUR): Blood pressure
Study 1496538 — Surrogate Endpoint (SUR): Serum creatinine
Study 6363949 — Surrogate Endpoint (SUR): Serum creatinine
Study 6363949 — Surrogate Endpoint (SUR): Blood pressure
Study 23237135 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 21827318 — Predictive Biomarker (PRD): LGSN mRNA
Genes: LGSN; GLULD1; LGS
Study 14755134 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14755134 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 3911699 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 16431933 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10853679 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 3546747 — Surrogate Endpoint (SUR): Blood pressure
Study 28731561 — Surrogate Endpoint (SUR): Blood pressure
Study 26695922 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21252141 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21252141 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30580652 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26835724 — Predictive Biomarker (PRD): FATE1 mRNA
Genes: FATE1; FATE
Study 20593911 — Surrogate Endpoint (SUR): Blood pressure
Study 30672832 — Surrogate Endpoint (SUR): Blood pressure
Study 16368450 — Surrogate Endpoint (SUR): Blood pressure
Study 12449447 — Surrogate Endpoint (SUR): Serum creatinine
Study 8597321 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1912915 — Surrogate Endpoint (SUR): Blood pressure
Study 30141966 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 27712932 — Surrogate Endpoint (SUR): Blood pressure