TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11959638 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 27203508 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22406878 — Surrogate Endpoint (SUR): Serum sodium
Study 30626222 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24582567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 24582567 — Predictive Biomarker (PRD): PTPN1 mRNA
Genes: PTPN1; PTP1B
Study 24582567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24582567 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 16525941 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11868011 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 9589654 — Surrogate Endpoint (SUR): Blood pressure
Study 28406788 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 25134530 — Surrogate Endpoint (SUR): Blood pressure
Study 17019375 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1717776 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1717776 — Surrogate Endpoint (SUR): Blood pressure
Study 22424822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22424822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29211967 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 29211967 — Predictive Biomarker (PRD): CYBC1 mRNA
Genes: CYBC1; C17orf62; EROS
Study 18576922 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7787145 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7787145 — Surrogate Endpoint (SUR): Blood pressure
Study 7787145 — Surrogate Endpoint (SUR): Serum creatinine
Study 24948656 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24948656 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 10608202 — Surrogate Endpoint (SUR): Blood pressure
Study 2040131 — Surrogate Endpoint (SUR): Blood pressure
Study 25641535 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25641535 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24379229 — Predictive Biomarker (PRD): SCAMP1 mRNA
Genes: SCAMP1; SCAMP
Study 20861716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1439512 — Surrogate Endpoint (SUR): Blood pressure
Study 22159820 — Surrogate Endpoint (SUR): Bone mineral density
Study 15860390 — Surrogate Endpoint (SUR): Blood pressure
Study 11973182 — Surrogate Endpoint (SUR): Blood pressure
Study 2248081 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 11464146 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11464146 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 7654481 — Surrogate Endpoint (SUR): Blood pressure
Study 31908129 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 23339054 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 30097463 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9316510 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9316510 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6645218 — Surrogate Endpoint (SUR): Serum sodium
Study 28056917 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 23959669 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 23959669 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 19656409 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19656409 — Surrogate Endpoint (SUR): Blood pressure
Study 16219018 — Surrogate Endpoint (SUR): Blood pressure
Study 10692984 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10692984 — Surrogate Endpoint (SUR): Bone mineral density
Study 8741209 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 26711786 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 26711786 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26711786 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 26711786 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 26711786 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22515513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23139259 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23139259 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11749817 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 27998961 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21345638 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 12680422 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6694348 — Surrogate Endpoint (SUR): Blood pressure
Study 24935999 — Surrogate Endpoint (SUR): Blood pressure
Study 20613496 — Surrogate Endpoint (SUR): Blood pressure
Study 326495 — Surrogate Endpoint (SUR): Blood pressure
Study 27260482 — Surrogate Endpoint (SUR): Bone mineral density
Study 21204889 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7579052 — Surrogate Endpoint (SUR): Blood pressure
Study 7579052 — Surrogate Endpoint (SUR): Serum creatinine
Study 24495468 — Surrogate Endpoint (SUR): Blood pressure
Study 15945402 — Surrogate Endpoint (SUR): Serum calcium
Study 9456288 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9456288 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9456288 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30606469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30606469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28077732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 12640509 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31897315 — Surrogate Endpoint (SUR): Blood pressure
Study 26656984 — Surrogate Endpoint (SUR): Blood pressure
Study 21457426 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21457426 — Surrogate Endpoint (SUR): Blood pressure
Study 25382328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25382328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25382328 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 19097473 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 12895359 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8994098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8994098 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 30926065 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 30926065 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30926065 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30926065 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25496727 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23328702 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23328702 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 27267854 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27267854 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 27267854 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27267854 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 27267854 — Surrogate Endpoint (SUR): Serum testosterone
Study 12176916 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 7598298 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7468984 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30231866 — Surrogate Endpoint (SUR): Blood pressure
Study 18195160 — Surrogate Endpoint (SUR): Blood pressure
Study 18195160 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18195160 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18195160 — Safety Biomarker (SAF): Interleukin 1
Study 15538568 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 10774589 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30684674 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26710216 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18594319 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 6616153 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 24080099 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24080099 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12505543 — Surrogate Endpoint (SUR): Blood pressure
Study 10508285 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10508285 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19477400 — Predictive Biomarker (PRD): SULT1E1 mRNA
Genes: SULT1E1; STE
Study 2397553 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15713724 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 20876366 — Surrogate Endpoint (SUR): Blood pressure
Study 2886822 — Surrogate Endpoint (SUR): Blood pressure
Study 23009573 — Surrogate Endpoint (SUR): Blood pressure
Study 16169319 — Surrogate Endpoint (SUR): Blood pressure
Study 8671908 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 8671908 — Surrogate Endpoint (SUR): Serum calcium
Study 1660550 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1660550 — Surrogate Endpoint (SUR): Blood pressure
Study 26218411 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23159479 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 14586743 — Surrogate Endpoint (SUR): Blood pressure
Study 14586743 — Surrogate Endpoint (SUR): Serum creatinine
Study 10756223 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1563463 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 1563463 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 23188130 — Surrogate Endpoint (SUR): Blood pressure
Study 21194898 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 7905217 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22177374 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 22177374 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 9247766 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9247766 — Surrogate Endpoint (SUR): Blood pressure
Study 3568582 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 3568582 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22677046 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22677046 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18618738 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15984601 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 2046054 — Surrogate Endpoint (SUR): Blood pressure
Study 31171039 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2037703 — Surrogate Endpoint (SUR): Blood pressure
Study 31943216 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 31943216 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 31943216 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 26864369 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17937567 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 15834296 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9425914 — Surrogate Endpoint (SUR): Serum creatinine
Study 31053945 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31053945 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 24849545 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 8762729 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 8762729 — Surrogate Endpoint (SUR): Blood pressure
Study 6813952 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6813952 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20714138 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 3247253 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24885921 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22269899 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 18403448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15813712 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 6139572 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 31797034 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31797034 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 23406994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19735557 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8422824 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3568947 — Predictive Biomarker (PRD): PIR mRNA
Genes: PIR
Study 3568947 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 22682149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22682149 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28029063 — Surrogate Endpoint (SUR): Blood pressure
Study 25448247 — Surrogate Endpoint (SUR): Blood pressure
Study 16537679 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 16296700 — Surrogate Endpoint (SUR): Blood pressure
Study 30975584 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 25944854 — Surrogate Endpoint (SUR): Blood pressure
Study 19552659 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11462061 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11462061 — Safety Biomarker (SAF): Reactive oxygen species
Study 24759040 — Surrogate Endpoint (SUR): Blood pressure
Study 16741040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16741040 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16741040 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15578258 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 30962676 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 28850308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15316335 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10204815 — Surrogate Endpoint (SUR): Blood pressure
Study 19293594 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7599447 — Surrogate Endpoint (SUR): Bone mineral density
Study 19667564 — Surrogate Endpoint (SUR): Blood pressure
Study 2057468 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21744011 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 16167254 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16167254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30998824 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15157383 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8161862 — Surrogate Endpoint (SUR): Blood pressure
Study 22366105 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29637282 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16229114 — Surrogate Endpoint (SUR): Blood pressure
Study 10470991 — Surrogate Endpoint (SUR): Blood pressure
Study 7890074 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27932278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12140794 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1053432 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23985254 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 18214709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2892499 — Surrogate Endpoint (SUR): Blood pressure
Study 16874157 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16874157 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11015164 — Surrogate Endpoint (SUR): Bone mineral density
Study 1459387 — Surrogate Endpoint (SUR): Blood pressure
Study 30109735 — Surrogate Endpoint (SUR): Blood pressure
Study 30109735 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27504006 — Surrogate Endpoint (SUR): Blood pressure
Study 24323034 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24323034 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 24323034 — Surrogate Endpoint (SUR): Serum testosterone
Study 10611554 — Surrogate Endpoint (SUR): Bone mineral density
Study 31567943 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 25785452 — Surrogate Endpoint (SUR): Blood pressure
Study 19106795 — Surrogate Endpoint (SUR): Blood pressure
Study 15259283 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 22647439 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 19605829 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17445898 — Surrogate Endpoint (SUR): Blood pressure
Study 16113430 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12575211 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 2088462 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 28641642 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 28641642 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 21883103 — Surrogate Endpoint (SUR): Blood pressure
Study 15221991 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15221991 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12149107 — Surrogate Endpoint (SUR): Blood pressure
Study 2674067 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7618457 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 16238908 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 1769643 — Surrogate Endpoint (SUR): Blood pressure
Study 31628482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26307030 — Predictive Biomarker (PRD): AHRR mRNA
Genes: AHRR; BHLHE77; KIAA1234
Study 24520101 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24520101 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17767476 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17767476 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17767476 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12231497 — Predictive Biomarker (PRD): DEFA1 mRNA
Genes: DEFA1; DEF1; DEFA2; MRS; DEFA1B
Study 10100062 — Surrogate Endpoint (SUR): Blood pressure
Study 6305183 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6305183 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11726414 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11726414 — Surrogate Endpoint (SUR): Blood pressure
Study 9394699 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9394699 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28393781 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28393781 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10889125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8957147 — Surrogate Endpoint (SUR): Blood pressure
Study 27397441 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27397441 — Surrogate Endpoint (SUR): Blood pressure
Study 17073850 — Surrogate Endpoint (SUR): Blood pressure
Study 16338276 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 16338276 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16338276 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 7720343 — Surrogate Endpoint (SUR): Blood pressure
Study 25753895 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25753895 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23817692 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 9834769 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21945511 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 21945511 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15102865 — Surrogate Endpoint (SUR): Blood pressure
Study 2491521 — Surrogate Endpoint (SUR): Blood pressure
Study 19603054 — Surrogate Endpoint (SUR): Blood pressure
Study 17338790 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15132303 — Surrogate Endpoint (SUR): Blood pressure
Study 25589782 — Surrogate Endpoint (SUR): Blood pressure
Study 30779531 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1