TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10872310 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30649227 — Predictive Biomarker (PRD): SCN9A mRNA
Genes: SCN9A; NENA
Study 25979609 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22902348 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 10886311 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10886311 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10886311 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 25234679 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20573926 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12942401 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 22222856 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 20212267 — Surrogate Endpoint (SUR): Blood pressure
Study 18567749 — Surrogate Endpoint (SUR): Blood pressure
Study 16020596 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10471608 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19781902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1970460 — Surrogate Endpoint (SUR): Blood pressure
Study 7019558 — Surrogate Endpoint (SUR): Blood pressure
Study 14973794 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 11573665 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11573665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28025025 — Surrogate Endpoint (SUR): Serum potassium
Study 3067546 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3067546 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 29649795 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29649795 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23110951 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 20609183 — Surrogate Endpoint (SUR): Serum creatinine
Study 2259928 — Surrogate Endpoint (SUR): Blood pressure
Study 42529 — Surrogate Endpoint (SUR): Serum testosterone
Study 17479444 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17479444 — Surrogate Endpoint (SUR): Blood pressure
Study 8018689 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9134445 — Surrogate Endpoint (SUR): Blood pressure
Study 30049691 — Surrogate Endpoint (SUR): Blood pressure
Study 23254595 — Surrogate Endpoint (SUR): Blood pressure
Study 18381567 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17064600 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9922408 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2109658 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 11355932 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 11355932 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study 11355932 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 23914845 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 20950405 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20950405 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 20950405 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17645558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17645558 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12800456 — Surrogate Endpoint (SUR): Blood pressure
Study 25909598 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 25909598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25909598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25909598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25132158 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 7801861 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 378733 — Surrogate Endpoint (SUR): Blood pressure
Study 20580216 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17854302 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 7117166 — Surrogate Endpoint (SUR): Blood pressure
Study 18024668 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 18024668 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 20627022 — Surrogate Endpoint (SUR): Blood pressure
Study 31464392 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25249397 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 25249397 — Predictive Biomarker (PRD): CXCR5 mRNA
Genes: CXCR5; BLR1; MDR15
Study 18003959 — Surrogate Endpoint (SUR): Bone mineral density
Study 18003959 — Surrogate Endpoint (SUR): Serum calcium
Study 8260695 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29972516 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22722637 — Surrogate Endpoint (SUR): Bone mineral density
Study 20842051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20842051 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 2378793 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23206440 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 23206440 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 23206440 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 18722681 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 18722681 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 18722681 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 15766446 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14625173 — Surrogate Endpoint (SUR): Blood pressure
Study 9026373 — Surrogate Endpoint (SUR): Blood pressure
Study 1791622 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1791622 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 1791622 — Surrogate Endpoint (SUR): Blood pressure
Study 6136793 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15765306 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12394652 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31498127 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 29496007 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26963434 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 22414635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22414635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12243435 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12243435 — Surrogate Endpoint (SUR): Blood pressure
Study 9836029 — Surrogate Endpoint (SUR): Blood pressure
Study 17283313 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 16793944 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 1718756 — Surrogate Endpoint (SUR): Blood pressure
Study 20236255 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12373693 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10022424 — Surrogate Endpoint (SUR): Blood pressure
Study 31960896 — Safety Biomarker (SAF): Hyaluronic acid
Study 24611967 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 10215997 — Predictive Biomarker (PRD): MAP2 mRNA
Genes: MAP2
Study 23535137 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23535137 — Surrogate Endpoint (SUR): Blood pressure
Study 16877271 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 25722532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24694475 — Surrogate Endpoint (SUR): Serum creatinine
Study 8786250 — Predictive Biomarker (PRD): NAPA mRNA
Genes: NAPA; SNAPA
Study 31449576 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21852542 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16338193 — Predictive Biomarker (PRD): SHC1 mRNA
Genes: SHC1; SHC; SHCA
Study 31405646 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24355401 — Predictive Biomarker (PRD): STT3A mRNA
Genes: STT3A; ITM1; TMC
Study 31307651 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 25538152 — Surrogate Endpoint (SUR): Blood pressure
Study 25538152 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8518372 — Surrogate Endpoint (SUR): Blood pressure
Study 28034704 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 24024769 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21454723 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 11397883 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11397883 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9268185 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 9268185 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 15626550 — Surrogate Endpoint (SUR): Blood pressure
Study 15626550 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15626550 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11689389 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9393221 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26507180 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 24418877 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19083462 — Surrogate Endpoint (SUR): Bone mineral density
Study 14768515 — Surrogate Endpoint (SUR): Blood pressure
Study 20032798 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18372722 — Predictive Biomarker (PRD): PHLPP1 mRNA
Genes: PHLPP1; KIAA0606; PHLPP; PLEKHE1; SCOP
Study 28162292 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 3553495 — Surrogate Endpoint (SUR): Blood pressure
Study 28417279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28417279 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19092335 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 8250362 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2944136 — Surrogate Endpoint (SUR): Blood pressure
Study 3234635 — Safety Biomarker (SAF): 51Cr-EDTA
Study 31902736 — Safety Biomarker (SAF): Hyaluronic acid
Study 31496659 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25963104 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21968856 — Predictive Biomarker (PRD): UNG mRNA
Genes: UNG; DGU; UNG1; UNG15
Study 9204512 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 28294373 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23510568 — Surrogate Endpoint (SUR): Blood pressure
Study 23510568 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18469238 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30680975 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 24950218 — Surrogate Endpoint (SUR): Blood pressure
Study 10868559 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10868559 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30400117 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 22238631 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 20714820 — Surrogate Endpoint (SUR): Blood pressure
Study 18508951 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15910012 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8656680 — Predictive Biomarker (PRD): CLEC4D mRNA
Genes: CLEC4D; CLECSF8; MCL
Study 14621753 — Surrogate Endpoint (SUR): Serum creatinine
Study 16082736 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 11374121 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11374121 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31940591 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 31940591 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22303704 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11134468 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9402542 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 23764181 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19887503 — Surrogate Endpoint (SUR): Blood pressure
Study 19887503 — Surrogate Endpoint (SUR): Serum creatinine
Study 12846705 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31952985 — Surrogate Endpoint (SUR): Serum sodium
Study 8990771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30409751 — Surrogate Endpoint (SUR): Blood pressure
Study 20953063 — Surrogate Endpoint (SUR): Blood pressure
Study 2166716 — Surrogate Endpoint (SUR): Blood pressure
Study 7106067 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21999398 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21999398 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7484829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7484829 — Surrogate Endpoint (SUR): Blood pressure
Study 28843184 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25997818 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25997818 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19167238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19167238 — Safety Biomarker (SAF): IL-6 and IL-10
Study 9609411 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2369792 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 27797015 — Surrogate Endpoint (SUR): Blood pressure
Study 19299471 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 19299471 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 19299471 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9623518 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 9623518 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 19779467 — Surrogate Endpoint (SUR): Blood pressure
Study 14709947 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9510662 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3936908 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3936908 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31079938 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 25122645 — Predictive Biomarker (PRD): RUNX2 mRNA
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 25122645 — Safety Biomarker (SAF): miR-200c
Genes: MIR200C
Study 16379551 — Surrogate Endpoint (SUR): Blood pressure
Study 16379551 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 10468903 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 2574764 — Surrogate Endpoint (SUR): Bone mineral density
Study 29588137 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 29588137 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 26268910 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 26268910 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21905248 — Surrogate Endpoint (SUR): Bone mineral density
Study 17078211 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25137523 — Surrogate Endpoint (SUR): Blood pressure
Study 2868900 — Surrogate Endpoint (SUR): Blood pressure
Study 10435809 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 7812552 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 19153426 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 8866933 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27440543 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 27440543 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27440543 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31145045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31145045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31145045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21106930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17885010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15166388 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8305411 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29202548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23672733 — Surrogate Endpoint (SUR): Blood pressure
Study 23088252 — Surrogate Endpoint (SUR): Serum sodium
Study 22410382 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 22410382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22410382 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22410382 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22410382 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 14693623 — Surrogate Endpoint (SUR): Blood pressure
Study 9700132 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9700132 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9700132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9700132 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 9700132 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30143478 — Surrogate Endpoint (SUR): Blood pressure
Study 25397623 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 25039273 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 22503610 — Surrogate Endpoint (SUR): Blood pressure
Study 15321153 — Surrogate Endpoint (SUR): Blood pressure
Study 7197959 — Surrogate Endpoint (SUR): Blood pressure
Study 28834330 — Surrogate Endpoint (SUR): Blood pressure
Study 26408012 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21542927 — Surrogate Endpoint (SUR): Blood pressure
Study 16206677 — Monitoring Biomarker (MOI): HBV DNA
Study 2403730 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30122911 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 25120315 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 20184605 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 25152604 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20493474 — Safety Biomarker (SAF): Cytochrome c
Study 15616757 — Surrogate Endpoint (SUR): Bone mineral density
Study 8814852 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 6376291 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 27003392 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1796618 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23833270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 20068585 — Surrogate Endpoint (SUR): Bone mineral density
Study 20068585 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29754402 — Surrogate Endpoint (SUR): Blood pressure
Study 29649309 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10901187 — Safety Biomarker (SAF): Reactive oxygen species
Study 23814850 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20633187 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 18230233 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 2302935 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30650500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22309114 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18372683 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 10221441 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 30476543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30476543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27560946 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 20053533 — Surrogate Endpoint (SUR): Blood pressure
Study 20053533 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20053533 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31549178 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22551440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 22551440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17191248 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9678794 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30279273 — Predictive Biomarker (PRD): DKK3 mRNA
Genes: DKK3; REIC; UNQ258/PRO295
Study 22924451 — Surrogate Endpoint (SUR): Exhaled carbon monoxide