TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31050034 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 8039040 — Surrogate Endpoint (SUR): Serum creatinine
Study 8039040 — Surrogate Endpoint (SUR): Blood pressure
Study 23712109 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 23712109 — Predictive Biomarker (PRD): PTGDS mRNA
Genes: PTGDS; PDS
Study 21852403 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3933736 — Surrogate Endpoint (SUR): Blood pressure
Study 21081251 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 24947595 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 19459773 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15526045 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15526045 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15526045 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11724652 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 7895178 — Surrogate Endpoint (SUR): Serum calcium
Study 28739134 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 20801941 — Surrogate Endpoint (SUR): Blood pressure
Study 9475575 — Surrogate Endpoint (SUR): Blood pressure
Study 7624490 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 2196359 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23033246 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22470031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28771018 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 27973414 — Surrogate Endpoint (SUR): Blood pressure
Study 23908187 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 22749176 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22749176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15540759 — Surrogate Endpoint (SUR): Blood pressure
Study 21029642 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11341172 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 30440913 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25180279 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19093057 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16280177 — Monitoring Biomarker (MOI): HBV DNA
Study 23373793 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12556074 — Surrogate Endpoint (SUR): Serum calcium
Study 12556074 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 12556074 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 7726669 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31714636 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 31714636 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31714636 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study 31714636 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 31714636 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26872721 — Surrogate Endpoint (SUR): Serum calcium
Study 26872721 — Surrogate Endpoint (SUR): Blood pressure
Study 393518 — Surrogate Endpoint (SUR): Blood pressure
Study 24115827 — Monitoring Biomarker (MOI): HBV DNA
Study 21887230 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21887230 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26386578 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 20738314 — Surrogate Endpoint (SUR): Bone mineral density
Study 18204233 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 16681888 — Predictive Biomarker (PRD): MYOC mRNA
Genes: MYOC; GLC1A; TIGR
Study 16681888 — Predictive Biomarker (PRD): OPTN mRNA
Genes: OPTN; FIP2; GLC1E; HIP7; HYPL; NRP
Study 15605213 — Surrogate Endpoint (SUR): Bone mineral density
Study 21364138 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 24662398 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 24662398 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23381198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10647760 — Surrogate Endpoint (SUR): Blood pressure
Study 2057034 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30152428 — Surrogate Endpoint (SUR): Serum creatinine
Study 30152428 — Surrogate Endpoint (SUR): Serum potassium
Study 24863570 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 24863570 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24863570 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 24863570 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 12418063 — Surrogate Endpoint (SUR): Serum testosterone
Study 11956045 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 11956045 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 761334 — Surrogate Endpoint (SUR): Blood pressure
Study 31634108 — Surrogate Endpoint (SUR): Blood pressure
Study 19948277 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19948277 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9234827 — Surrogate Endpoint (SUR): Blood pressure
Study 26589105 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20160653 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18515689 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1728527 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18501061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18501061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30358156 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 18418962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10325897 — Surrogate Endpoint (SUR): Bone mineral density
Study 20798339 — Surrogate Endpoint (SUR): Blood pressure
Study 18586814 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 16320349 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7081096 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31405875 — Surrogate Endpoint (SUR): Blood pressure
Study 26700109 — Surrogate Endpoint (SUR): Blood pressure
Study 26700109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11870165 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 3476058 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 1919423 — Surrogate Endpoint (SUR): Blood pressure
Study 26273146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26273146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24589724 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 17971946 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 17971946 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11447080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11447080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11447080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15470487 — Predictive Biomarker (PRD): KLRD1 mRNA
Genes: KLRD1; CD94
Study 11467911 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 7976460 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 19244691 — Surrogate Endpoint (SUR): Blood pressure
Study 9291702 — Surrogate Endpoint (SUR): Serum creatinine
Study 29779815 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 29779815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29779815 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22687580 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31959263 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 31959263 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 31959263 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 31959263 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 31959263 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 31959263 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 30777024 — Monitoring Biomarker (MOI): HBV DNA
Study 15306152 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 9421239 — Surrogate Endpoint (SUR): Bone mineral density
Study 20444845 — Surrogate Endpoint (SUR): Bone mineral density
Study 11359431 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9217273 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9217273 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 9217273 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 3325090 — Surrogate Endpoint (SUR): Blood pressure
Study 25365012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25365012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8635377 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 29036427 — Surrogate Endpoint (SUR): Blood pressure
Study 8615705 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8615705 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30985644 — Surrogate Endpoint (SUR): Blood pressure
Study 25887103 — Predictive Biomarker (PRD): SLC25A3 mRNA
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 30612858 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8678065 — Surrogate Endpoint (SUR): Serum creatinine
Study 8678065 — Surrogate Endpoint (SUR): Serum calcium
Study 8678065 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 8678065 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 8591624 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 2760254 — Surrogate Endpoint (SUR): Blood pressure
Study 29188863 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26004026 — Safety Biomarker (SAF): Hyaluronic acid
Study 15258329 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 10691900 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 30975047 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 29427355 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 29427355 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 26536214 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8909433 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10075382 — Surrogate Endpoint (SUR): Blood pressure
Study 2139303 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26823793 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22884505 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22884505 — Surrogate Endpoint (SUR): Pathological complete response
Study 1336998 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29140227 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 25660493 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15476476 — Surrogate Endpoint (SUR): Serum creatinine
Study 28237861 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14740601 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14740601 — Surrogate Endpoint (SUR): Blood pressure
Study 9307742 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29114972 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study 15776267 — Safety Biomarker (SAF): Hyaluronic acid
Study 12012627 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30449071 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 25697379 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 10941601 — Surrogate Endpoint (SUR): Blood pressure
Study 10941601 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1588260 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 25093998 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 18683819 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 16179660 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28636405 — Surrogate Endpoint (SUR): Blood pressure
Study 25394762 — Surrogate Endpoint (SUR): Blood pressure
Study 28937313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28937313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17474951 — Predictive Biomarker (PRD): ARX mRNA
Genes: ARX
Study 11463009 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 11463009 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 20443014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30503849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30503849 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21057704 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 11052464 — Surrogate Endpoint (SUR): Serum calcium
Study 11052464 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 11052464 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 6386484 — Surrogate Endpoint (SUR): Blood pressure
Study 21806683 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 2644129 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 301745 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 301745 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 23742144 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23742144 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30110693 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30110693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30110693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7620695 — Surrogate Endpoint (SUR): Blood pressure
Study 2490833 — Surrogate Endpoint (SUR): Serum creatinine
Study 2490833 — Surrogate Endpoint (SUR): Blood pressure
Study 31652226 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18346185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27220601 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 27220601 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 27220601 — Safety Biomarker (SAF): Reactive oxygen species
Study 27220601 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 22650145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20606481 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15683483 — Predictive Biomarker (PRD): WBP2NL mRNA
Genes: WBP2NL; PAWP
Study 10421921 — Surrogate Endpoint (SUR): Blood pressure
Study 28786523 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 28786523 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 2972597 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28628969 — Surrogate Endpoint (SUR): Blood pressure
Study 24824900 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 12828103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12828103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9206238 — Safety Biomarker (SAF): Human leucocyte antigen
Study 3579494 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 20679559 — Surrogate Endpoint (SUR): Blood pressure
Study 20679559 — Surrogate Endpoint (SUR): Bone mineral density
Study 20679559 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20679559 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21776461 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21776461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3129318 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31476881 — Surrogate Endpoint (SUR): Blood pressure
Study 12011136 — Predictive Biomarker (PRD): Hormone receptor
Study 10210974 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25239030 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 31730832 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30762744 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 28940638 — Surrogate Endpoint (SUR): Blood pressure
Study 17198101 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 31043522 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27683405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27683405 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27683405 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 27683405 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 21360353 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 15025744 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 7523785 — Surrogate Endpoint (SUR): Blood pressure
Study 30728951 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 26464453 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26464453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12200242 — Surrogate Endpoint (SUR): Bone mineral density
Study 27778256 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 19281922 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19281922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17407516 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 15184247 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9605372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7013560 — Surrogate Endpoint (SUR): Blood pressure
Study 19674695 — Surrogate Endpoint (SUR): Blood pressure
Study 15960063 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 7735265 — Surrogate Endpoint (SUR): Blood pressure
Study 31088511 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 11774111 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11774111 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20528005 — Surrogate Endpoint (SUR): Serum potassium
Study 29523095 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 7194733 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 30252571 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30252571 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9918565 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8589013 — Surrogate Endpoint (SUR): Serum calcium
Study 8589013 — Surrogate Endpoint (SUR): Serum creatinine
Study 343678 — Predictive Biomarker (PRD): HBE1 mRNA
Genes: HBE1; HBE
Study 28392272 — Surrogate Endpoint (SUR): Serum creatinine
Study 28392272 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28392272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23826104 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21419704 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 19641312 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19641312 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 19641312 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 17317676 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17317676 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 15851147 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 7819101 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31954696 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 27424313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12670780 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1895369 — Surrogate Endpoint (SUR): Blood pressure
Study 22130104 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22130104 — Surrogate Endpoint (SUR): Serum sodium
Study 31968396 — Safety Biomarker (SAF): miR-142
Genes: MIR142
Study 31968396 — Predictive Biomarker (PRD): miR-15a-5p
Genes: MIR15A
Study 31968396 — Safety Biomarker (SAF): miR-15a
Genes: MIR15A
Study 31968396 — Safety Biomarker (SAF): miR-22
Genes: MIR22
Study 31922265 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25123162 — Predictive Biomarker (PRD): MARCKS mRNA
Genes: MARCKS; MACS; PRKCSL