TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11196128 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 1724116 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26031460 — Predictive Biomarker (PRD): CCR1 mRNA
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 27582675 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 22544804 — Monitoring Biomarker (MOI): HBV DNA
Study 22544804 — Surrogate Endpoint (SUR): Bone mineral density
Study 15721096 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3519451 — Surrogate Endpoint (SUR): Blood pressure
Study 30632023 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30632023 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28639860 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23883636 — Surrogate Endpoint (SUR): Bone mineral density
Study 16271155 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 12114411 — Predictive Biomarker (PRD): CDH3 mRNA
Genes: CDH3; CDHP
Study 11123415 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 8737631 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3994782 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10839470 — Surrogate Endpoint (SUR): Blood pressure
Study 29394998 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30609978 — Surrogate Endpoint (SUR): Blood pressure
Study 24189171 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 24189171 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 22848045 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 22848045 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 22848045 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 15062892 — Surrogate Endpoint (SUR): Blood pressure
Study 9850026 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31810064 — Surrogate Endpoint (SUR): Blood pressure
Study 19906801 — Surrogate Endpoint (SUR): Bone mineral density
Study 10539823 — Surrogate Endpoint (SUR): Blood pressure
Study 2288653 — Monitoring Biomarker (MOI): HBV DNA
Study 24470436 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24043137 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18838929 — Surrogate Endpoint (SUR): Blood pressure
Study 23114379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23114379 — Surrogate Endpoint (SUR): Blood pressure
Study 15889697 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7664546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7664546 — Safety Biomarker (SAF): Interleukin 1
Study 7664546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30618324 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 23150149 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 3902677 — Surrogate Endpoint (SUR): Blood pressure
Study 30950970 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20151341 — Surrogate Endpoint (SUR): Blood pressure
Study 19140507 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26493812 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26493812 — Surrogate Endpoint (SUR): Serum calcium
Study 17203013 — Surrogate Endpoint (SUR): Blood pressure
Study 14597346 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 14597346 — Predictive Biomarker (PRD): ERBB2 mRNA
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10425569 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21288228 — Surrogate Endpoint (SUR): Blood pressure
Study 19262478 — Surrogate Endpoint (SUR): Blood pressure
Study 31524498 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25376434 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 21664867 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17537152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27319277 — Safety Biomarker (SAF): Reactive oxygen species
Study 18632591 — Surrogate Endpoint (SUR): Serum creatinine
Study 29397594 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29397594 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 29397594 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29397594 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31108180 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26586093 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26586093 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31870938 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 18316115 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18316115 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18316115 — Surrogate Endpoint (SUR): Blood pressure
Study 14698516 — Surrogate Endpoint (SUR): Bacterial count
Study 1721980 — Surrogate Endpoint (SUR): Blood pressure
Study 31126570 — Surrogate Endpoint (SUR): Blood pressure
Study 22479361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17515696 — Surrogate Endpoint (SUR): Serum calcium
Study 9182470 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16369463 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20406214 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21763211 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 21763211 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 16920590 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 9208358 — Surrogate Endpoint (SUR): Blood pressure
Study 7778531 — Surrogate Endpoint (SUR): Blood pressure
Study 28100544 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21056284 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9032097 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25135124 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25135124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25135124 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19933916 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18812366 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1932484 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 30430667 — Surrogate Endpoint (SUR): Blood pressure
Study 24808486 — Surrogate Endpoint (SUR): Blood pressure
Study 791330 — Surrogate Endpoint (SUR): Blood pressure
Study 31395306 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 28151543 — Surrogate Endpoint (SUR): Blood pressure
Study 14738208 — Predictive Biomarker (PRD): APRT mRNA
Genes: APRT
Study 14738208 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 1384898 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29389579 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23970645 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12451982 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23028103 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 11820714 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 31665455 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26806566 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 16860028 — Surrogate Endpoint (SUR): Blood pressure
Study 12701987 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29917140 — Predictive Biomarker (PRD): Hormone receptor
Study 29917140 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22534335 — Surrogate Endpoint (SUR): Sperm parameters
Study 30634036 — Surrogate Endpoint (SUR): Blood pressure
Study 20673325 — Surrogate Endpoint (SUR): Blood pressure
Study 11092514 — Surrogate Endpoint (SUR): Blood pressure
Study 31025894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22950816 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 26857999 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26857999 — Surrogate Endpoint (SUR): Blood pressure
Study 22552602 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 20377413 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 20377413 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30019318 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30019318 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 16278262 — Surrogate Endpoint (SUR): Bone mineral density
Study 16278262 — Surrogate Endpoint (SUR): Serum calcium
Study 9605804 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8581394 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8581394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8581394 — Safety Biomarker (SAF): Interleukin 1
Study 27644475 — Surrogate Endpoint (SUR): Blood pressure
Study 10528035 — Monitoring Biomarker (MOI): HBV DNA
Study 6128875 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27951475 — Surrogate Endpoint (SUR): Blood pressure
Study 20020207 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 25782323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19318471 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15698940 — Surrogate Endpoint (SUR): Bone mineral density
Study 23514054 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23514054 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 23514054 — Safety Biomarker (SAF): Interleukin 1
Study 17457340 — Surrogate Endpoint (SUR): Blood pressure
Study 12940842 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10679756 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 8148487 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8148487 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2568211 — Surrogate Endpoint (SUR): Blood pressure
Study 2568211 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27436368 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 19536890 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10748773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7250173 — Surrogate Endpoint (SUR): Blood pressure
Study 31020400 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28351163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28351163 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28351163 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26521223 — Surrogate Endpoint (SUR): Blood pressure
Study 1310465 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1310465 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 23669880 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 23669880 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 20063429 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 12742478 — Surrogate Endpoint (SUR): Serum creatinine
Study 10803800 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 30463831 — Surrogate Endpoint (SUR): Blood pressure
Study 27248440 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27248440 — Surrogate Endpoint (SUR): Blood pressure
Study 20002624 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20002624 — Surrogate Endpoint (SUR): Blood pressure
Study 20002624 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18698545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18698545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18698545 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18698545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2522729 — Surrogate Endpoint (SUR): Blood pressure
Study 5072236 — Surrogate Endpoint (SUR): Blood pressure
Study 24373610 — Predictive Biomarker (PRD): PCSK7 mRNA
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 18686631 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 18686631 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 16118546 — Safety Biomarker (SAF): Interleukin 1
Study 16118546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16118546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14519753 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8965890 — Surrogate Endpoint (SUR): Serum calcium
Study 26329313 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 26329313 — Surrogate Endpoint (SUR): Blood pressure
Study 11888869 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 25201152 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22855633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22855633 — Monitoring Biomarker (MOI): Procalcitonin
Study 22855633 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22855633 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 22855633 — Safety Biomarker (SAF): Human leucocyte antigen
Study 21037443 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 18679829 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 18679829 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 19914598 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 18655556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18655556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18655556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31448513 — Predictive Biomarker (PRD): Hormone receptor
Study 11497197 — Surrogate Endpoint (SUR): Blood pressure
Study 8296738 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30572482 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21733334 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 21733334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21733334 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18772858 — Surrogate Endpoint (SUR): Blood pressure
Study 9730298 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 23331240 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 9296422 — Surrogate Endpoint (SUR): Blood pressure
Study 25052847 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25052847 — Safety Biomarker (SAF): BDNF
Study 19535710 — Surrogate Endpoint (SUR): Blood pressure
Study 9236673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9236673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 9236673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9236673 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 9236673 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 9236673 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 21382512 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 18996868 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28045585 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 12537922 — Surrogate Endpoint (SUR): Blood pressure
Study 6169578 — Surrogate Endpoint (SUR): Blood pressure
Study 29863966 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 15019536 — Safety Biomarker (SAF): MTHFR
Study 9222184 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 7702801 — Surrogate Endpoint (SUR): Blood pressure
Study 25903799 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 1655315 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 26814235 — Surrogate Endpoint (SUR): Blood pressure
Study 15837826 — Surrogate Endpoint (SUR): Blood pressure
Study 12578875 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 12578875 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11347858 — Surrogate Endpoint (SUR): Blood pressure
Study 3909840 — Surrogate Endpoint (SUR): Blood pressure
Study 29438199 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18246429 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 31718583 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31718583 — Safety Biomarker (SAF): BDNF
Study 24690383 — Surrogate Endpoint (SUR): Blood pressure
Study 31388720 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 22887834 — Surrogate Endpoint (SUR): Blood pressure
Study 15335019 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 10930895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9780100 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 18245904 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 18245904 — Safety Biomarker (SAF): Hyaluronic acid
Study 12765983 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8636587 — Surrogate Endpoint (SUR): Blood pressure
Study 31028503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19497624 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15588135 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 9228516 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28860166 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 28860166 — Predictive Biomarker (PRD): ATF3 mRNA
Genes: ATF3
Study 25769195 — Surrogate Endpoint (SUR): Blood pressure
Study 3707799 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30001944 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28557652 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 23893190 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 11151744 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10606280 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 6337742 — Surrogate Endpoint (SUR): Blood pressure
Study 6337742 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19445819 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15338257 — Safety Biomarker (SAF): Reactive oxygen species
Study 31978882 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30446594 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 17551931 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10821722 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10821722 — Surrogate Endpoint (SUR): Blood pressure
Study 10754344 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10754344 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21963017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21963017 — Surrogate Endpoint (SUR): Blood pressure
Study 18590111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18590111 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7773216 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26700065 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8556568 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 25587804 — Surrogate Endpoint (SUR): Blood pressure
Study 11216965 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31233169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11253266 — Surrogate Endpoint (SUR): Blood pressure
Study 25399731 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25399731 — Surrogate Endpoint (SUR): Blood pressure
Study 18606612 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 24655485 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 8536677 — Pharmacodynamic Biomarker (PDY): Homovanillic acid