TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29677629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29677629 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8195906 — Surrogate Endpoint (SUR): Blood pressure
Study 26414004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22425471 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 18356686 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18356686 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12402619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12402619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23683140 — Surrogate Endpoint (SUR): Blood pressure
Study 11443167 — Surrogate Endpoint (SUR): Blood pressure
Study 11443167 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11443167 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8032955 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26017715 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19549403 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15189174 — Predictive Biomarker (PRD): ADCY10 mRNA
Genes: ADCY10; SAC
Study 15189174 — Surrogate Endpoint (SUR): Serum creatinine
Study 7947368 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 7947368 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27738330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27738330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20698734 — Surrogate Endpoint (SUR): Blood pressure
Study 14597872 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 2079567 — Monitoring Biomarker (MOI): HBV DNA
Study 25886568 — Surrogate Endpoint (SUR): Blood pressure
Study 14662111 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26710892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26710892 — Surrogate Endpoint (SUR): Probing pocket depth
Study 20650039 — Surrogate Endpoint (SUR): Blood pressure
Study 30955915 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 30955915 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25099983 — Surrogate Endpoint (SUR): Blood pressure
Study 21924651 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22918596 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22918596 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18030234 — Monitoring Biomarker (MOI): HBV DNA
Study 6760074 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 28334365 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 28334365 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 26363442 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23471307 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9116392 — Surrogate Endpoint (SUR): Bone mineral density
Study 22713145 — Predictive Biomarker (PRD): STK39 mRNA
Genes: STK39; SPAK
Study 22713145 — Surrogate Endpoint (SUR): Blood pressure
Study 29162334 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 26654880 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 22405597 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 10861141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10861141 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24356620 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 12045677 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8545290 — Surrogate Endpoint (SUR): Blood pressure
Study 29462094 — Surrogate Endpoint (SUR): Bone mineral density
Study 1992876 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 31486297 — Surrogate Endpoint (SUR): Bone mineral density
Study 26913636 — Surrogate Endpoint (SUR): Blood pressure
Study 22891799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22891799 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22891799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16984937 — Predictive Biomarker (PRD): ASPRV1 mRNA
Genes: ASPRV1; SASP
Study 7934538 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20849499 — Predictive Biomarker (PRD): PPIA mRNA
Genes: PPIA; CYPA
Study 30574864 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15561650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26939316 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8545563 — Surrogate Endpoint (SUR): Blood pressure
Study 6756484 — Surrogate Endpoint (SUR): Blood pressure
Study 30888584 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30888584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23681940 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 20363843 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 20363843 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15778423 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 1781562 — Surrogate Endpoint (SUR): Blood pressure
Study 31567988 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31567988 — Surrogate Endpoint (SUR): Blood pressure
Study 31567988 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27117175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27117175 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24976416 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 24976416 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24976416 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21750118 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 19770669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19770669 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12715373 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 18490173 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8967601 — Surrogate Endpoint (SUR): Blood pressure
Study 31477562 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25158865 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16311656 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12923641 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12225796 — Predictive Biomarker (PRD): THPO mRNA
Genes: THPO; MGDF
Study 20803425 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20803425 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12610804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12610804 — Surrogate Endpoint (SUR): Bone mineral density
Study 12610804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19725009 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 11516807 — Surrogate Endpoint (SUR): Blood pressure
Study 8314271 — Surrogate Endpoint (SUR): Blood pressure
Study 15583920 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18235048 — Surrogate Endpoint (SUR): Blood pressure
Study 18235048 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12569298 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 12569298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27401305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27401305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27401305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24948653 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 20450622 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 18838525 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1535568 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30118368 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 9491438 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9491438 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 7877303 — Surrogate Endpoint (SUR): Blood pressure
Study 16721305 — Surrogate Endpoint (SUR): Blood pressure
Study 25940537 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24007452 — Surrogate Endpoint (SUR): Blood pressure
Study 9344298 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8250653 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 26210489 — Surrogate Endpoint (SUR): Blood pressure
Study 19548435 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15529389 — Surrogate Endpoint (SUR): Bone mineral density
Study 28958437 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28958437 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17328944 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11715357 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8260367 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30946851 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 26299164 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19554672 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 14982884 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 14982884 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28569132 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 28569132 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28569132 — Safety Biomarker (SAF): BDNF
Study 19923038 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17461852 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 12928045 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 12928045 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 9367461 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 9367461 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28783969 — Safety Biomarker (SAF): Hyaluronic acid
Study 1533771 — Surrogate Endpoint (SUR): Blood pressure
Study 25297613 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 11544433 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 9164520 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 3556051 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1125653 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31784217 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 31784217 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 26711194 — Surrogate Endpoint (SUR): Bone mineral density
Study 11323501 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27064499 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8214993 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8214993 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23672789 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23672789 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21732669 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study 19185634 — Surrogate Endpoint (SUR): Blood pressure
Study 10217370 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7038316 — Surrogate Endpoint (SUR): Blood pressure
Study 31630358 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31630358 — Surrogate Endpoint (SUR): Blood pressure
Study 18018769 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16081875 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9920144 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7501353 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 30683195 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 2205135 — Surrogate Endpoint (SUR): Blood pressure
Study 26485404 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21422411 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23597479 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 23597479 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10836723 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 9180622 — Surrogate Endpoint (SUR): Blood pressure
Study 8607407 — Surrogate Endpoint (SUR): Blood pressure
Study 19397752 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19397752 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17940111 — Surrogate Endpoint (SUR): Serum testosterone
Study 17940111 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16513420 — Surrogate Endpoint (SUR): Blood pressure
Study 11544429 — Surrogate Endpoint (SUR): Blood pressure
Study 16888455 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 1432432 — Surrogate Endpoint (SUR): Serum creatinine
Study 3917900 — Surrogate Endpoint (SUR): Blood pressure
Study 30053413 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 30053413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26060452 — Surrogate Endpoint (SUR): Serum calcium
Study 12108857 — Surrogate Endpoint (SUR): Bone mineral density
Study 1967210 — Surrogate Endpoint (SUR): Blood pressure
Study 24055306 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 21865396 — Predictive Biomarker (PRD): MYO1G mRNA
Genes: MYO1G; HA2
Study 10620209 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6084121 — Surrogate Endpoint (SUR): Blood pressure
Study 31555926 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 20336066 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 10404912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24495883 — Safety Biomarker (SAF): Reactive oxygen species
Study 21049628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17877120 — Safety Biomarker (SAF): Reactive oxygen species
Study 12121506 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12121506 — Monitoring Biomarker (MOI): HBV DNA
Study 7539822 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7027062 — Surrogate Endpoint (SUR): Serum calcium
Study 7027062 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31419239 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19246334 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11826546 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11826546 — Surrogate Endpoint (SUR): Blood pressure
Study 31990684 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25490907 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 25490907 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 16422971 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 11159876 — Predictive Biomarker (PRD): LGALSL mRNA
Genes: LGALSL; GRP; HSPC159
Study 11159876 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 25559146 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23878024 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 20185386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18185506 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 12714797 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 2294687 — Surrogate Endpoint (SUR): Blood pressure
Study 31401654 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 22704274 — Surrogate Endpoint (SUR): Blood pressure
Study 22704274 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12479110 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 9667255 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 29247273 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 24955452 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 15888053 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24338935 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24338935 — Surrogate Endpoint (SUR): Blood pressure
Study 23198694 — Surrogate Endpoint (SUR): Blood pressure
Study 11136485 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9693995 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 7935635 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 29156056 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17655947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17655947 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21321426 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19761681 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19761681 — Surrogate Endpoint (SUR): Blood pressure
Study 10896408 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26840887 — Safety Biomarker (SAF): Hyaluronic acid
Study 18824996 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 12833584 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12833584 — Surrogate Endpoint (SUR): Blood pressure
Study 10567194 — Surrogate Endpoint (SUR): Blood pressure
Study 1818788 — Surrogate Endpoint (SUR): Blood pressure
Study 27777219 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24663014 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18805108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30734418 — Surrogate Endpoint (SUR): Blood pressure
Study 12809958 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12809958 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11015339 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 9129860 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24756128 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 29587582 — Surrogate Endpoint (SUR): Serum potassium
Study 25697852 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 20795383 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20795383 — Predictive Biomarker (PRD): CD72 mRNA
Genes: CD72
Study 18421050 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 2105795 — Surrogate Endpoint (SUR): Blood pressure
Study 30459073 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30459073 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7266950 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18550472 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16555496 — Surrogate Endpoint (SUR): Blood pressure
Study 27854139 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 27130714 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study 27130714 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24587320 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 24587320 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 17034536 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 31707149 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 31707149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 16087795 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16087795 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16087795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7742149 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6112844 — Surrogate Endpoint (SUR): Blood pressure
Study 10912758 — Surrogate Endpoint (SUR): Blood pressure
Study 9531185 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9531185 — Surrogate Endpoint (SUR): Serum creatinine
Study 28718527 — Safety Biomarker (SAF): Hyaluronic acid