TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29282650 — Predictive Biomarker (PRD): KCNIP3 mRNA
Genes: KCNIP3; CSEN; DREAM; KCHIP3
Study 29282650 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 7838417 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31395418 — Surrogate Endpoint (SUR): Blood pressure
Study 25863422 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17045409 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 3899669 — Surrogate Endpoint (SUR): Blood pressure
Study 20103685 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20103685 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18271233 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11872551 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1770314 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24818764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24818764 — Safety Biomarker (SAF): Hyaluronic acid
Study 22639399 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 7722116 — Safety Biomarker (SAF): Cytochrome c
Study 7270476 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31561651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27179664 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11484963 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25413366 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23531317 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23531317 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22279570 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 19013285 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19013285 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30343388 — Predictive Biomarker (PRD): PLAAT3 mRNA
Genes: PLAAT3; HRASLS3; HREV107; PLA2G16
Study 27218216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27218216 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16546756 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 7894540 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 31603281 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 28551778 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23987657 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 20888993 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 8755686 — Surrogate Endpoint (SUR): Blood pressure
Study 25443605 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 25443605 — Surrogate Endpoint (SUR): Serum creatinine
Study 17925871 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 1453750 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 30046610 — Monitoring Biomarker (MOI): Procalcitonin
Study 30046610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18343246 — Surrogate Endpoint (SUR): Blood pressure
Study 30409962 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30409962 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 20028464 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 15821487 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 1936485 — Surrogate Endpoint (SUR): Blood pressure
Study 6217028 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9695724 — Surrogate Endpoint (SUR): Blood pressure
Study 9462387 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 7520297 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29297230 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 29297230 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29297230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29297230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29297230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10505800 — Surrogate Endpoint (SUR): Bone mineral density
Study 25766689 — Surrogate Endpoint (SUR): Blood pressure
Study 28247979 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 20386078 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20386078 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20356911 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11403364 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11403364 — Surrogate Endpoint (SUR): Blood pressure
Study 8167164 — Surrogate Endpoint (SUR): Blood pressure
Study 29696564 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 26849256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24429127 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19086328 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19086328 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 10450292 — Surrogate Endpoint (SUR): Blood pressure
Study 2018658 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2018658 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28277823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22708417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22708417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18842422 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 18842422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18842422 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18842422 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 18842422 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27718781 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27718781 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14556925 — Surrogate Endpoint (SUR): Serum creatinine
Study 8636433 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6731261 — Surrogate Endpoint (SUR): Blood pressure
Study 26609008 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17685870 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28577680 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 14602795 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 2946507 — Surrogate Endpoint (SUR): Blood pressure
Study 24588644 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 20230914 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 12878791 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23969321 — Surrogate Endpoint (SUR): Blood pressure
Study 19593941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19593941 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19593941 — Surrogate Endpoint (SUR): Blood pressure
Study 11394697 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31066887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29892933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29892933 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17047001 — Predictive Biomarker (PRD): NR4A3 mRNA
Genes: NR4A3; CHN; CSMF; MINOR; NOR1; TEC
Study 12913774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12913774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8536777 — Surrogate Endpoint (SUR): Serum testosterone
Study 1780418 — Surrogate Endpoint (SUR): Blood pressure
Study 15203796 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 11740317 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28662983 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 28662983 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28662983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25927404 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 21489882 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6149939 — Surrogate Endpoint (SUR): Blood pressure
Study 27374222 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 20500832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20500832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17312304 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28711384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21031576 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 21031576 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 21031576 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31958548 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17656028 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 15522043 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9023596 — Surrogate Endpoint (SUR): Blood pressure
Study 19001772 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19001772 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15850081 — Surrogate Endpoint (SUR): Blood pressure
Study 19361897 — Surrogate Endpoint (SUR): Blood pressure
Study 23204164 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23204164 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 23204164 — Safety Biomarker (SAF): Cytochrome c
Study 19842230 — Surrogate Endpoint (SUR): Pathological complete response
Study 14605789 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 14605789 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14605789 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19155521 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): GZMB mRNA
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 19155521 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 19155521 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 19155521 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 19155521 — Predictive Biomarker (PRD): CCND2 mRNA
Genes: CCND2
Study 19155521 — Predictive Biomarker (PRD): LGALS2 mRNA
Genes: LGALS2
Study 11402107 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8931784 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1298087 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30852478 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30852478 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29378038 — Surrogate Endpoint (SUR): Blood pressure
Study 24709926 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22668876 — Monitoring Biomarker (MOI): HBV DNA
Study 17506733 — Surrogate Endpoint (SUR): Blood pressure
Study 16163516 — Surrogate Endpoint (SUR): Blood pressure
Study 12149701 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 12149701 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2261147 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25095322 — Surrogate Endpoint (SUR): Blood pressure
Study 19074488 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 16829763 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 14520944 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 11153413 — Surrogate Endpoint (SUR): Blood pressure
Study 29939885 — Surrogate Endpoint (SUR): Bacterial count
Study 28473423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23131717 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23131717 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21441163 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31094482 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24810310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17334592 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 17334592 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31090337 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31090337 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 31090337 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 31090337 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29024233 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22559752 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 18574553 — Surrogate Endpoint (SUR): Blood pressure
Study 10404791 — Surrogate Endpoint (SUR): Bone mineral density
Study 10404791 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 6987028 — Surrogate Endpoint (SUR): Blood pressure
Study 18528511 — Surrogate Endpoint (SUR): Blood pressure
Study 18528511 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12919181 — Predictive Biomarker (PRD): DUSP2 mRNA
Genes: DUSP2; PAC1
Study 1361274 — Surrogate Endpoint (SUR): Blood pressure
Study 6238209 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 26554619 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 22509337 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20116145 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 6371367 — Surrogate Endpoint (SUR): Serum potassium
Study 1463154 — Surrogate Endpoint (SUR): Blood pressure
Study 2418736 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 29632098 — Surrogate Endpoint (SUR): Blood pressure
Study 27070747 — Surrogate Endpoint (SUR): Blood pressure
Study 29100681 — Predictive Biomarker (PRD): UMPS mRNA
Genes: UMPS; OK/SW-cl.21
Study 26338891 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26338891 — Surrogate Endpoint (SUR): Blood pressure
Study 26338891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26338891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23147161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21606858 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 15155300 — Surrogate Endpoint (SUR): Blood pressure
Study 11446941 — Surrogate Endpoint (SUR): Blood pressure
Study 15566926 — Surrogate Endpoint (SUR): Blood pressure
Study 23963821 — Surrogate Endpoint (SUR): Bone mineral density
Study 12496537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8899661 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 1642145 — Surrogate Endpoint (SUR): Bone mineral density
Study 26611433 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study 26611433 — Surrogate Endpoint (SUR): Blood pressure
Study 25172519 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12145055 — Surrogate Endpoint (SUR): Blood pressure
Study 2079453 — Surrogate Endpoint (SUR): Serum creatinine
Study 29256406 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 23829828 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 23829828 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23829828 — Surrogate Endpoint (SUR): Serum creatinine
Study 31207400 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23980529 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study 23980529 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 15221995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11698939 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27049055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10934074 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26856040 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12885977 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31780142 — Predictive Biomarker (PRD): TCP1 mRNA
Genes: TCP1; CCT1; CCTA
Study 31122656 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31122656 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10886696 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 10492099 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29898192 — Safety Biomarker (SAF): BDNF
Study 11806986 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 11806986 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28685960 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 22327053 — Surrogate Endpoint (SUR): Blood pressure
Study 19534616 — Surrogate Endpoint (SUR): Blood pressure
Study 10805064 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 10805064 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 10805064 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31242936 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25420946 — Surrogate Endpoint (SUR): Blood pressure
Study 23435801 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 11320110 — Surrogate Endpoint (SUR): Blood pressure
Study 8165852 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20519679 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10705222 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12733372 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12733372 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31587084 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 31326433 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 31326433 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 31326433 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 31326433 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 7775858 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29064792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29064792 — Surrogate Endpoint (SUR): Blood pressure
Study 25296247 — Surrogate Endpoint (SUR): Blood pressure
Study 27631270 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 27631270 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 27631270 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 14601484 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 31962198 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29943522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29943522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27537606 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 20137138 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 10890862 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1390326 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 1390326 — Surrogate Endpoint (SUR): Blood pressure
Study 30325849 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16563920 — Surrogate Endpoint (SUR): Blood pressure
Study 10545574 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2253662 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30043207 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14635510 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 10516865 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15903129 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30278529 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30278529 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15975490 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH