TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10088569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7502702 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7502702 — Surrogate Endpoint (SUR): Bone mineral density
Study 18784223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18784223 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18784223 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8701408 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 26863054 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 9844762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26468956 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24494283 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15041595 — Surrogate Endpoint (SUR): Blood pressure
Study 9429011 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3010707 — Surrogate Endpoint (SUR): Blood pressure
Study 12959960 — Safety Biomarker (SAF): Reactive oxygen species
Study 8590608 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 2800986 — Surrogate Endpoint (SUR): Blood pressure
Study 19781409 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 28873709 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 26964180 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26964180 — Surrogate Endpoint (SUR): Blood pressure
Study 9279218 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8201610 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30166304 — Surrogate Endpoint (SUR): Blood pressure
Study 16391172 — Surrogate Endpoint (SUR): Blood pressure
Study 14597946 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22573476 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22573476 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22573476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20552577 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 20552577 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15983240 — Surrogate Endpoint (SUR): Blood pressure
Study 24139323 — Predictive Biomarker (PRD): OSR1 mRNA
Genes: OSR1; ODD
Study 8886999 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 8886999 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8886999 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2058593 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 2058593 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2058593 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30395052 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30270178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22968245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19560905 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 22357413 — Surrogate Endpoint (SUR): Blood pressure
Study 8106772 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10394257 — Surrogate Endpoint (SUR): Blood pressure
Study 8893576 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25556937 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23339698 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 23339698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23339698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15755830 — Surrogate Endpoint (SUR): Blood pressure
Study 10758046 — Surrogate Endpoint (SUR): Blood pressure
Study 30235745 — Predictive Biomarker (PRD): PCNT mRNA
Genes: PCNT; KIAA0402; PCNT2
Study 20701468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18654867 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14501815 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30613009 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30613009 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 18678301 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 18678301 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 7609510 — Surrogate Endpoint (SUR): Blood pressure
Study 3303427 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 10589274 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26620373 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 10858728 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 31870046 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 31870046 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 27094945 — Surrogate Endpoint (SUR): Serum uric acid
Study 27094945 — Surrogate Endpoint (SUR): Serum creatinine
Study 22891748 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12658028 — Surrogate Endpoint (SUR): Blood pressure
Study 2540785 — Surrogate Endpoint (SUR): Blood pressure
Study 339337 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 339337 — Surrogate Endpoint (SUR): Serum calcium
Study 18368792 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 27380104 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 19937984 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 21399960 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 17383302 — Surrogate Endpoint (SUR): Blood pressure
Study 11136300 — Surrogate Endpoint (SUR): Blood pressure
Study 11136300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1333267 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17954694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 10810425 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27703344 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12868184 — Safety Biomarker (SAF): Reactive oxygen species
Study 8501265 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 29752998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29752998 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29752998 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22691263 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24977699 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24977699 — Surrogate Endpoint (SUR): Blood pressure
Study 20300897 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20300897 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9122012 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28320856 — Surrogate Endpoint (SUR): Blood pressure
Study 24014831 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 24014831 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25523578 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 20621700 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 12886046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12886046 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20660695 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 20660695 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 20660695 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17674476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17674476 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 17674476 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17674476 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8942410 — Surrogate Endpoint (SUR): Blood pressure
Study 8942410 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29607730 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23442823 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17663803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17676423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15207999 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28050702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28050702 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28050702 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21131871 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31377776 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31377776 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 31702015 — Surrogate Endpoint (SUR): Bone mineral density
Study 18648227 — Surrogate Endpoint (SUR): Blood pressure
Study 17032193 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8371143 — Surrogate Endpoint (SUR): Blood pressure
Study 25402495 — Surrogate Endpoint (SUR): Serum potassium
Study 16303055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16303055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16303055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26817809 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31397771 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 14748941 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 14748941 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29364340 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17141318 — Predictive Biomarker (PRD): CTSD mRNA
Genes: CTSD; CPSD
Study 10404741 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10404741 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7733123 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 7733123 — Surrogate Endpoint (SUR): Bone mineral density
Study 7733123 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 15086491 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 15086491 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15086491 — Safety Biomarker (SAF): Reactive oxygen species
Study 15086491 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11116287 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24210600 — Surrogate Endpoint (SUR): Blood pressure
Study 9595523 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9595523 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19930762 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 1091138 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 1091138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1091138 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21900886 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 21900886 — Predictive Biomarker (PRD): ADH1B mRNA
Genes: ADH1B; ADH2
Study 2885638 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2885638 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 2885638 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 2885638 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 20816190 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8002639 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 11161545 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Albumin mRNA
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9806287 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26964163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8306744 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 2686494 — Surrogate Endpoint (SUR): Blood pressure
Study 26159065 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17847938 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 30173337 — Predictive Biomarker (PRD): RHOJ mRNA
Genes: RHOJ; ARHJ; RASL7B; RHOI; TCL
Study 18656509 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 18656509 — Surrogate Endpoint (SUR): Blood pressure
Study 6367098 — Surrogate Endpoint (SUR): Blood pressure
Study 6367098 — Surrogate Endpoint (SUR): Serum potassium
Study 26872828 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 18418976 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7652635 — Surrogate Endpoint (SUR): Blood pressure
Study 2650942 — Surrogate Endpoint (SUR): Blood pressure
Study 389513 — Surrogate Endpoint (SUR): Blood pressure
Study 30922146 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30922146 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30922146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26376344 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 21159432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9389779 — Surrogate Endpoint (SUR): Bone mineral density
Study 24850107 — Surrogate Endpoint (SUR): Blood pressure
Study 21226953 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14526151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1483490 — Surrogate Endpoint (SUR): Serum calcium
Study 31382524 — Surrogate Endpoint (SUR): Blood pressure
Study 26119561 — Safety Biomarker (SAF): Urinary microalbumin
Study 22747752 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22747752 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22747752 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 22747752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31039663 — Surrogate Endpoint (SUR): Blood pressure
Study 31039663 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31039663 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28468648 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 26052700 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11791759 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7730872 — Surrogate Endpoint (SUR): Blood pressure
Study 28467729 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9316823 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28723587 — Surrogate Endpoint (SUR): Blood pressure
Study 25465324 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18799723 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 20589696 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17549054 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 17549054 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9075448 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8445289 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 25464511 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 10810461 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 1739172 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1739172 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 30130674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18727656 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16198658 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 16198658 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16198658 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 16198658 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 16198658 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 28758155 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 15697105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15697105 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12172440 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7577315 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31058457 — Surrogate Endpoint (SUR): Blood pressure
Study 8623963 — Surrogate Endpoint (SUR): Blood pressure
Study 28822828 — Surrogate Endpoint (SUR): Blood pressure
Study 26720458 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 20048271 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20048271 — Surrogate Endpoint (SUR): Blood pressure
Study 31234840 — Surrogate Endpoint (SUR): Blood pressure
Study 29217757 — Surrogate Endpoint (SUR): Blood pressure
Study 21814293 — Surrogate Endpoint (SUR): Blood pressure
Study 19339405 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 21795297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21795297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11595381 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 11595381 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16333028 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9504437 — Surrogate Endpoint (SUR): Blood pressure
Study 29187388 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29187388 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25194428 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25194428 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22402823 — Surrogate Endpoint (SUR): Blood pressure
Study 11119744 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31914443 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24595228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24595228 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24595228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19939196 — Surrogate Endpoint (SUR): Blood pressure
Study 1836824 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1836824 — Surrogate Endpoint (SUR): Blood pressure
Study 20530296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20530296 — Surrogate Endpoint (SUR): Blood pressure
Study 18411833 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15599116 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21432597 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9591449 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9591449 — Monitoring Biomarker (MOI): Complement C4
Study 23059810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19875685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31102988 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24130072 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22108485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16310924 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9061804 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29742109 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 23428336 — Safety Biomarker (SAF): L-acetylcarnitine
Study 16937274 — Surrogate Endpoint (SUR): Bone mineral density
Study 9083616 — Safety Biomarker (SAF): Interleukin 1
Study 23031471 — Predictive Biomarker (PRD): CP mRNA
Genes: CP