TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7778075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17911499 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29946649 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23632203 — Surrogate Endpoint (SUR): Blood pressure
Study 21620395 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9049456 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31181206 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16432054 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16432054 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9239399 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30251109 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30251109 — Surrogate Endpoint (SUR): Blood pressure
Study 24515256 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 18471061 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8645644 — Surrogate Endpoint (SUR): Blood pressure
Study 18925392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18925392 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study 29900909 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15802855 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15802855 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2037418 — Surrogate Endpoint (SUR): Blood pressure
Study 25887759 — Surrogate Endpoint (SUR): Blood pressure
Study 15972619 — Surrogate Endpoint (SUR): Bone mineral density
Study 15996249 — Surrogate Endpoint (SUR): Serum creatinine
Study 12441833 — Surrogate Endpoint (SUR): Blood pressure
Study 10501408 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30328031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30328031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30328031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24439959 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 12068793 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7879301 — Surrogate Endpoint (SUR): Blood pressure
Study 24980134 — Surrogate Endpoint (SUR): Blood pressure
Study 12955029 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 10543415 — Surrogate Endpoint (SUR): Bone mineral density
Study 1907740 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 1907740 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 31319653 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 31319653 — Predictive Biomarker (PRD): ATG16L1 mRNA
Genes: ATG16L1; APG16L; UNQ9393/PRO34307
Study 31319653 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 31319653 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 10769854 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10769854 — Surrogate Endpoint (SUR): Blood pressure
Study 8394861 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 21977987 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21977987 — Predictive Biomarker (PRD): APOC1 mRNA
Genes: APOC1
Study 21977987 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 21977987 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 21977987 — Predictive Biomarker (PRD): FEN1 mRNA
Genes: FEN1; RAD2
Study 21977987 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 21977987 — Predictive Biomarker (PRD): PSRC1 mRNA
Genes: PSRC1; DDA3; FP3214
Study 12957728 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 12957728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12957728 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19049846 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 17953640 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 17953640 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 12163983 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 12163983 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 25267008 — Surrogate Endpoint (SUR): Blood pressure
Study 22659250 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 20084316 — Surrogate Endpoint (SUR): Blood pressure
Study 15381386 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11432884 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 11432884 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25766261 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19579599 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23280243 — Surrogate Endpoint (SUR): Blood pressure
Study 20622199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11504165 — Surrogate Endpoint (SUR): Blood pressure
Study 30328936 — Surrogate Endpoint (SUR): Blood pressure
Study 29146648 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29146648 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21309841 — Surrogate Endpoint (SUR): Blood pressure
Study 18958384 — Surrogate Endpoint (SUR): Bone mineral density
Study 15224654 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15383188 — Surrogate Endpoint (SUR): Blood pressure
Study 15383188 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15383188 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25635420 — Surrogate Endpoint (SUR): Blood pressure
Study 21848460 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 17209178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15179406 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 15179406 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9543133 — Surrogate Endpoint (SUR): Bone mineral density
Study 16686562 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 8960720 — Surrogate Endpoint (SUR): Blood pressure
Study 24485397 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22335395 — Surrogate Endpoint (SUR): Blood pressure
Study 28444936 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 28444936 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28444936 — Surrogate Endpoint (SUR): Blood pressure
Study 24411134 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 880971 — Surrogate Endpoint (SUR): Blood pressure
Study 21904779 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21904779 — Surrogate Endpoint (SUR): Blood pressure
Study 18673303 — Surrogate Endpoint (SUR): Blood pressure
Study 3018602 — Surrogate Endpoint (SUR): Blood pressure
Study 3018602 — Surrogate Endpoint (SUR): Serum creatinine
Study 23065656 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18840101 — Surrogate Endpoint (SUR): Blood pressure
Study 17153886 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14969156 — Surrogate Endpoint (SUR): Blood pressure
Study 1739798 — Surrogate Endpoint (SUR): Blood pressure
Study 28619005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16944194 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16944194 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24991787 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23690531 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20300080 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20300080 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20300080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31104282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27101726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27101726 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30196723 — Surrogate Endpoint (SUR): Blood pressure
Study 22370992 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11824860 — Surrogate Endpoint (SUR): Blood pressure
Study 6291889 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 22289659 — Surrogate Endpoint (SUR): Serum calcium
Study 2710995 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23566344 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21746979 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9205633 — Surrogate Endpoint (SUR): Bone mineral density
Study 9205633 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 25894960 — Surrogate Endpoint (SUR): Serum testosterone
Study 25191599 — Surrogate Endpoint (SUR): Blood pressure
Study 25191599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9401829 — Surrogate Endpoint (SUR): Blood pressure
Study 28714771 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 11985407 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15307698 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12531809 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 21796128 — Surrogate Endpoint (SUR): Blood pressure
Study 21796128 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21796128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19587440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15290731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12612946 — Surrogate Endpoint (SUR): Blood pressure
Study 12612946 — Surrogate Endpoint (SUR): Serum creatinine
Study 30909690 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 22817122 — Surrogate Endpoint (SUR): Serum calcium
Study 22817122 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 20136474 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 9784666 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 26649464 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 17403704 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16422873 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10411372 — Surrogate Endpoint (SUR): Blood pressure
Study 7572595 — Surrogate Endpoint (SUR): Blood pressure
Study 10573065 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 2032147 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2032147 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 2032147 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2032147 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8955759 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 1597983 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11910310 — Surrogate Endpoint (SUR): Blood pressure
Study 11910310 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11910310 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9426828 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 2643892 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 31998472 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 21406601 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21406601 — Surrogate Endpoint (SUR): Blood pressure
Study 17890444 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15042130 — Surrogate Endpoint (SUR): Blood pressure
Study 7025500 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19820906 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11914251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9210501 — Surrogate Endpoint (SUR): Serum creatinine
Study 9210501 — Surrogate Endpoint (SUR): Blood pressure
Study 3621278 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 31958932 — Predictive Biomarker (PRD): ACRC mRNA
Genes: GCNA; ACRC
Study 24368613 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 10095804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21314449 — Surrogate Endpoint (SUR): Blood pressure
Study 19843669 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 19843669 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 11734734 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 25394242 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 25394242 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 25394242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7753538 — Surrogate Endpoint (SUR): Blood pressure
Study 27471208 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9952145 — Surrogate Endpoint (SUR): Blood pressure
Study 6777812 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26951309 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study 17219171 — Surrogate Endpoint (SUR): Blood pressure
Study 24748593 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 24748593 — Surrogate Endpoint (SUR): Blood pressure
Study 10647066 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9296311 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9296311 — Surrogate Endpoint (SUR): Blood pressure
Study 20485957 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26771340 — Surrogate Endpoint (SUR): Blood pressure
Study 17328070 — Surrogate Endpoint (SUR): Serum creatinine
Study 18497598 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17174704 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22128042 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19150743 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12153554 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7543891 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 322922 — Predictive Biomarker (PRD): NAPA mRNA
Genes: NAPA; SNAPA
Study 23829604 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 17196507 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12127031 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 2752698 — Surrogate Endpoint (SUR): Blood pressure
Study 2752698 — Surrogate Endpoint (SUR): Serum potassium
Study 20976802 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 20976802 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 20976802 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 402831 — Surrogate Endpoint (SUR): Blood pressure
Study 24866348 — Surrogate Endpoint (SUR): Blood pressure
Study 19821717 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8346819 — Surrogate Endpoint (SUR): Blood pressure
Study 3518912 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31740106 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 26584035 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 18182447 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 16687344 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11024215 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9236507 — Surrogate Endpoint (SUR): Blood pressure
Study 8384096 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8384096 — Surrogate Endpoint (SUR): Blood pressure
Study 30296325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26412463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15795184 — Surrogate Endpoint (SUR): Blood pressure
Study 8507448 — Surrogate Endpoint (SUR): Blood pressure
Study 31714470 — Surrogate Endpoint (SUR): Bone mineral density
Study 30283014 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 30283014 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 1898694 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1898694 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21550556 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11244189 — Surrogate Endpoint (SUR): Blood pressure
Study 2503114 — Surrogate Endpoint (SUR): Blood pressure
Study 31918452 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18813917 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 10698387 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9412257 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31562799 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 11156644 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 15501704 — Surrogate Endpoint (SUR): Bone mineral density
Study 27648674 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 20091404 — Surrogate Endpoint (SUR): Bone mineral density
Study 10904461 — Surrogate Endpoint (SUR): Blood pressure
Study 9291340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9291340 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7686709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7686709 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 30583933 — Surrogate Endpoint (SUR): Blood pressure
Study 25382740 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 27737534 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 22688605 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 22688605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21777715 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 4096071 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31737686 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 29929990 — Surrogate Endpoint (SUR): Blood pressure
Study 26966825 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17618954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11023477 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8228207 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8228207 — Surrogate Endpoint (SUR): Blood pressure
Study 3521858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31067190 — Surrogate Endpoint (SUR): Blood pressure
Study 17191734 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 22307477 — Predictive Biomarker (PRD): ADH1C mRNA
Genes: ADH1C; ADH3
Study 24033696 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 24033696 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 20234305 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 324257 — Surrogate Endpoint (SUR): Blood pressure
Study 8936955 — Monitoring Biomarker (MOI): HBV DNA
Study 28679529 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 28679529 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 26545535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31798891 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 31798891 — Predictive Biomarker (PRD): DAPK3 mRNA
Genes: DAPK3; ZIPK
Study 31798891 — Predictive Biomarker (PRD): PER1 mRNA
Genes: PER1; KIAA0482; PER; RIGUI
Study 31798891 — Predictive Biomarker (PRD): TNFAIP3 mRNA
Genes: TNFAIP3; OTUD7C
Study 18622250 — Surrogate Endpoint (SUR): Blood pressure
Study 9892589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31658543 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31658543 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 31658543 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15472191 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15472191 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 15472191 — Surrogate Endpoint (SUR): Bone mineral density
Study 29652246 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein