TrialPanorama/TrialPanorama-database huggingface dataset:
Study 14988901 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26497059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29504427 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21239518 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 3917352 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 24553909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16258091 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 25663642 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25663642 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 19190819 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19190819 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 19190819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11243949 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27654143 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 21737232 — Surrogate Endpoint (SUR): Blood pressure
Study 21737232 — Surrogate Endpoint (SUR): Serum creatinine
Study 14688692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 31185079 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26853484 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23764967 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27562361 — Surrogate Endpoint (SUR): Blood pressure
Study 22947342 — Surrogate Endpoint (SUR): Blood pressure
Study 29317812 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24662570 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24662570 — Safety Biomarker (SAF): BDNF
Study 31786466 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 30535668 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 29089468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29089468 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25245572 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 25245572 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7832135 — Surrogate Endpoint (SUR): Blood pressure
Study 2225705 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25911605 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25911605 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19717488 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 19717488 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 19717488 — Predictive Biomarker (PRD): PTPN1 mRNA
Genes: PTPN1; PTP1B
Study 19717488 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 19717488 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 27385940 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 1993795 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1993795 — Surrogate Endpoint (SUR): Blood pressure
Study 22892393 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15956121 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 15956121 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15956121 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15956121 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 15956121 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12427152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8493299 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 22045595 — Predictive Biomarker (PRD): Hormone receptor
Study 19308365 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11584153 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26472406 — Predictive Biomarker (PRD): DMRTA1 mRNA
Genes: DMRTA1; DMO
Study 26472406 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 20005750 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 19033012 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16630941 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1313765 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1313765 — Surrogate Endpoint (SUR): Blood pressure
Study 26541264 — Surrogate Endpoint (SUR): Blood pressure
Study 24286443 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 24286443 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 22464260 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 20158897 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11877267 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11877267 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 11877267 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 401827 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 28461862 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 24972700 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9111463 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 2901266 — Surrogate Endpoint (SUR): Blood pressure
Study 21715583 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 16836557 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12569270 — Surrogate Endpoint (SUR): Blood pressure
Study 9114765 — Surrogate Endpoint (SUR): Blood pressure
Study 9114765 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9114765 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30026341 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27423645 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20438395 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 18457472 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18457472 — Surrogate Endpoint (SUR): Bone mineral density
Study 16995893 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10433851 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22772170 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20142523 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 17477888 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 22114787 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22114787 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7814812 — Monitoring Biomarker (MOI): HBV DNA
Study 15017527 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15017527 — Surrogate Endpoint (SUR): Blood pressure
Study 2877129 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2877129 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2877129 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12589153 — Surrogate Endpoint (SUR): Bone mineral density
Study 30629585 — Surrogate Endpoint (SUR): Blood pressure
Study 17966072 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15564357 — Surrogate Endpoint (SUR): Blood pressure
Study 28854833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28854833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24599010 — Predictive Biomarker (PRD): OSCAR mRNA
Genes: OSCAR
Study 24599010 — Surrogate Endpoint (SUR): Blood pressure
Study 17945470 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 10592355 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10592355 — Surrogate Endpoint (SUR): Serum creatinine
Study 6273027 — Surrogate Endpoint (SUR): Serum creatinine
Study 6273027 — Surrogate Endpoint (SUR): Serum calcium
Study 21416219 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21416219 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15641936 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7114339 — Surrogate Endpoint (SUR): Blood pressure
Study 16730732 — Surrogate Endpoint (SUR): Blood pressure
Study 16009786 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16009786 — Surrogate Endpoint (SUR): Blood pressure
Study 22245322 — Surrogate Endpoint (SUR): Bone mineral density
Study 26581683 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 24690159 — Predictive Biomarker (PRD): APOA5 mRNA
Genes: APOA5; RAP3; UNQ411/PRO773
Study 18620598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26920441 — Surrogate Endpoint (SUR): Blood pressure
Study 25589677 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 16775579 — Surrogate Endpoint (SUR): Serum testosterone
Study 19816871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19816871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17234504 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2680677 — Surrogate Endpoint (SUR): Blood pressure
Study 2680677 — Surrogate Endpoint (SUR): Serum creatinine
Study 2680677 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9631134 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24924232 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24924232 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19767812 — Surrogate Endpoint (SUR): Blood pressure
Study 19767812 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7756106 — Predictive Biomarker (PRD): SLC38A3 mRNA
Genes: SLC38A3; G17; NAT1; SN1; SNAT3
Study 21763472 — Surrogate Endpoint (SUR): Blood pressure
Study 15603203 — Surrogate Endpoint (SUR): Blood pressure
Study 2884860 — Surrogate Endpoint (SUR): Blood pressure
Study 30371278 — Surrogate Endpoint (SUR): Blood pressure
Study 25996101 — Surrogate Endpoint (SUR): Pathological complete response
Study 23213070 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 19880460 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 8333814 — Surrogate Endpoint (SUR): Blood pressure
Study 26286128 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 23743161 — Surrogate Endpoint (SUR): Blood pressure
Study 23743161 — Safety Biomarker (SAF): Urinary microalbumin
Study 23743161 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23743161 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16856623 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16856623 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31755803 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28643618 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 23306828 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 6233093 — Surrogate Endpoint (SUR): Blood pressure
Study 25057809 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25057809 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 25057809 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 25057809 — Predictive Biomarker (PRD): GPX4 mRNA
Genes: GPX4
Study 25057809 — Predictive Biomarker (PRD): TXN mRNA
Genes: TXN; TRDX; TRX; TRX1
Study 25057809 — Predictive Biomarker (PRD): TXNRD1 mRNA
Genes: TXNRD1; GRIM12; KDRF
Study 22761409 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20465650 — Predictive Biomarker (PRD): MITF mRNA
Genes: MITF; BHLHE32
Study 20465650 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 18703472 — Surrogate Endpoint (SUR): Bone mineral density
Study 15851913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15851913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15851913 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12576957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9804518 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 197800 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9771208 — Surrogate Endpoint (SUR): Bone mineral density
Study 8116547 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8116547 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28350328 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28350328 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17690547 — Surrogate Endpoint (SUR): Blood pressure
Study 15161435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15702625 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15702625 — Surrogate Endpoint (SUR): Blood pressure
Study 9352972 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29239893 — Surrogate Endpoint (SUR): Bone mineral density
Study 28145966 — Surrogate Endpoint (SUR): Blood pressure
Study 26637993 — Surrogate Endpoint (SUR): Blood pressure
Study 12952111 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 10372699 — Surrogate Endpoint (SUR): Bone mineral density
Study 7237025 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27525817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15682483 — Monitoring Biomarker (MOI): HBV DNA
Study 10598660 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20375791 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 6837242 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 29336387 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29336387 — Surrogate Endpoint (SUR): Blood pressure
Study 19643620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2338698 — Surrogate Endpoint (SUR): Blood pressure
Study 19236805 — Predictive Biomarker (PRD): CBR1 mRNA
Genes: CBR1; CBR; CRN; SDR21C1
Study 2733576 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27743738 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 24614165 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19996728 — Surrogate Endpoint (SUR): Serum creatinine
Study 19167590 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19167590 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 15500196 — Surrogate Endpoint (SUR): Blood pressure
Study 30398957 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 24837466 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24837466 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 15101020 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12234946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12234946 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25928131 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 22089773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11316896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31206613 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 28729158 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28729158 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 23732643 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 21823280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20082923 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27058753 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 22770683 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20043983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11895470 — Surrogate Endpoint (SUR): Blood pressure
Study 2644151 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 21705552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12771320 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 8175200 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26718095 — Surrogate Endpoint (SUR): Blood pressure
Study 1826253 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1826253 — Surrogate Endpoint (SUR): Blood pressure
Study 29793488 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29793488 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29793488 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15121020 — Surrogate Endpoint (SUR): Bone mineral density
Study 18840641 — Surrogate Endpoint (SUR): Bone mineral density
Study 27955995 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27955995 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19528362 — Surrogate Endpoint (SUR): Blood pressure
Study 27933720 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7502282 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 6256422 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 24723075 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19708636 — Predictive Biomarker (PRD): SLMAP mRNA
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 17417700 — Surrogate Endpoint (SUR): Bone mineral density
Study 9589688 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29182708 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27140797 — Predictive Biomarker (PRD): FFAR1 mRNA
Genes: FFAR1; GPR40
Study 31090592 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 23354282 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20658564 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20658564 — Surrogate Endpoint (SUR): Bone mineral density
Study 165029 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28723333 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21603894 — Surrogate Endpoint (SUR): Blood pressure
Study 2439568 — Monitoring Biomarker (MOI): HBV DNA
Study 25617503 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 25617503 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 18928094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18928094 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18928094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18928094 — Safety Biomarker (SAF): IL-6 and IL-10
Study 8547558 — Surrogate Endpoint (SUR): Blood pressure
Study 8547558 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24445757 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24445757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19638648 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17289479 — Surrogate Endpoint (SUR): Blood pressure
Study 6604469 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28143739 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 28143739 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8385478 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26264387 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 23053255 — Predictive Biomarker (PRD): CDK5 mRNA
Genes: CDK5; CDKN5; PSSALRE
Study 23053255 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16059590 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 7733040 — Surrogate Endpoint (SUR): Bone mineral density
Study 1682593 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 21249385 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21249385 — Surrogate Endpoint (SUR): Blood pressure
Study 27951511 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25709428 — Surrogate Endpoint (SUR): Blood pressure
Study 20962290 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 2070108 — Surrogate Endpoint (SUR): Blood pressure