TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10707752 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10707752 — Surrogate Endpoint (SUR): Serum creatinine
Study 23070803 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 14606076 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14606076 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 14606076 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 14606076 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 14606076 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 14606076 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30666153 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30666153 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30666153 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30928925 — Surrogate Endpoint (SUR): Blood pressure
Study 26468074 — Surrogate Endpoint (SUR): Blood pressure
Study 17507345 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17507345 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11229465 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 11229465 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 11229465 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 11229465 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11229465 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 7908257 — Surrogate Endpoint (SUR): Blood pressure
Study 29910837 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21628653 — Predictive Biomarker (PRD): TMPRSS13 mRNA
Genes: TMPRSS13; MSP; TMPRSS11
Study 16969059 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 11867823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11867823 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30541586 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 19346662 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19346662 — Surrogate Endpoint (SUR): Blood pressure
Study 30926369 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 30926369 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 26870788 — Safety Biomarker (SAF): Cytochrome c
Study 19262457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15272899 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 9242341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9242341 — Safety Biomarker (SAF): Interleukin 1
Study 9242341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8494702 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15983288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15983288 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15983288 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11999911 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 11999911 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 11999911 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 11999911 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10372975 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10372975 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25728846 — Surrogate Endpoint (SUR): Serum potassium
Study 25728846 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29073815 — Safety Biomarker (SAF): Hyaluronic acid
Study 18756037 — Surrogate Endpoint (SUR): Serum creatinine
Study 11731729 — Surrogate Endpoint (SUR): Blood pressure
Study 9256187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9256187 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28129251 — Surrogate Endpoint (SUR): Blood pressure
Study 25585949 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25585949 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21350054 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11463545 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9663723 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 27032074 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18672254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30791079 — Surrogate Endpoint (SUR): Blood pressure
Study 15367192 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31839158 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 29329305 — Monitoring Biomarker (MOI): HBV DNA
Study 31596518 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 31596518 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23576043 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 19514093 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 15456623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9237962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27225988 — Surrogate Endpoint (SUR): Serum creatinine
Study 27225988 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25256892 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 25256892 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25256892 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10028374 — Surrogate Endpoint (SUR): Blood pressure
Study 30143879 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23113934 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 1586375 — Surrogate Endpoint (SUR): Blood pressure
Study 26354383 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 20543706 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12527967 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22780937 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20547990 — Predictive Biomarker (PRD): Hormone receptor
Study 12860863 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28721992 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21423021 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 21423021 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 21423021 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 17038251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12355570 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 6159865 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 25981758 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 19375250 — Surrogate Endpoint (SUR): Blood pressure
Study 11584084 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 11584084 — Safety Biomarker (SAF): MTHFR
Study 7886652 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7886652 — Surrogate Endpoint (SUR): Blood pressure
Study 2190927 — Surrogate Endpoint (SUR): Blood pressure
Study 12831591 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 9921711 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8677862 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1984373 — Surrogate Endpoint (SUR): Blood pressure
Study 29291739 — Surrogate Endpoint (SUR): Blood pressure
Study 24674234 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 20530518 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 16169400 — Safety Biomarker (SAF): L-acetylcarnitine
Study 12501022 — Surrogate Endpoint (SUR): Blood pressure
Study 1715478 — Surrogate Endpoint (SUR): Blood pressure
Study 29073347 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 22160637 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 22160637 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22160637 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 15781339 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 12148881 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12148881 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12148881 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10589004 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27981528 — Surrogate Endpoint (SUR): Blood pressure
Study 576887 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 31277784 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30946207 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30946207 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27651331 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27651331 — Surrogate Endpoint (SUR): Blood pressure
Study 9230275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 18174609 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18174609 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29940166 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 29940166 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 15730542 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 12538173 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1623657 — Surrogate Endpoint (SUR): Blood pressure
Study 19307271 — Surrogate Endpoint (SUR): Blood pressure
Study 17595032 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 17595032 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17595032 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10855738 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 10855738 — Surrogate Endpoint (SUR): Blood pressure
Study 1288925 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22839514 — Surrogate Endpoint (SUR): Blood pressure
Study 15983321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15983321 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29927860 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25005893 — Predictive Biomarker (PRD): GMCL2 mRNA
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 25005893 — Predictive Biomarker (PRD): PHLDA2 mRNA
Genes: PHLDA2; BWR1C; HLDA2; IPL; TSSC3
Study 19387899 — Surrogate Endpoint (SUR): Blood pressure
Study 19387899 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17151807 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 14674932 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9020283 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20510974 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 20510974 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12436219 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7699968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2566284 — Surrogate Endpoint (SUR): Blood pressure
Study 27988297 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 23711530 — Monitoring Biomarker (MOI): Procalcitonin
Study 17165022 — Predictive Biomarker (PRD): MMP12 mRNA
Genes: MMP12; HME
Study 9527417 — Surrogate Endpoint (SUR): Bacterial count
Study 30486682 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30486682 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17052779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11552016 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9722293 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10707032 — Surrogate Endpoint (SUR): Blood pressure
Study 10707032 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9018517 — Surrogate Endpoint (SUR): Plasma ammonia
Study 20926006 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16096169 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 8792730 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8792730 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8792730 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8792730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1637513 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1637513 — Surrogate Endpoint (SUR): Blood pressure
Study 29672821 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 27109860 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 27109860 — Surrogate Endpoint (SUR): Blood pressure
Study 30541645 — Surrogate Endpoint (SUR): Serum sodium
Study 30541645 — Surrogate Endpoint (SUR): Serum creatinine
Study 28199143 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28199143 — Predictive Biomarker (PRD): DHDDS mRNA
Genes: DHDDS; HDS
Study 17228991 — Surrogate Endpoint (SUR): Blood pressure
Study 9004051 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 29618772 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19556519 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9139621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1848567 — Surrogate Endpoint (SUR): Bacterial count
Study 18030515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25150183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25150183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25150183 — Monitoring Biomarker (MOI): Procalcitonin
Study 25150183 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22097972 — Monitoring Biomarker (MOI): HBV DNA
Study 19638620 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 17941284 — Surrogate Endpoint (SUR): Blood pressure
Study 9622279 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7841755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 7841755 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9032182 — Safety Biomarker (SAF): Reactive oxygen species
Study 28675520 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 26371168 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26371168 — Surrogate Endpoint (SUR): Blood pressure
Study 25495720 — Surrogate Endpoint (SUR): Blood pressure
Study 25495720 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25495720 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17555561 — Predictive Biomarker (PRD): TFF1 mRNA
Genes: TFF1; BCEI; PS2
Study 17555561 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 17555561 — Predictive Biomarker (PRD): PDZK1 mRNA
Genes: PDZK1; CAP70; NHERF3; PDZD1
Study 17555561 — Predictive Biomarker (PRD): AGR2 mRNA
Genes: AGR2; AG2; UNQ515/PRO1030
Study 17555561 — Predictive Biomarker (PRD): LUM mRNA
Genes: LUM; LDC; SLRR2D
Study 17555561 — Predictive Biomarker (PRD): DCN mRNA
Genes: DCN; SLRR1B
Study 17555561 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17555561 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15223728 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15223728 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 15223728 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15223728 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22057896 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22057896 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 16790625 — Surrogate Endpoint (SUR): Blood pressure
Study 15609652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9600792 — Surrogate Endpoint (SUR): Bone mineral density
Study 31735362 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 16352794 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17501760 — Predictive Biomarker (PRD): EIF2AK2 mRNA
Genes: EIF2AK2; PKR; PRKR
Study 31565242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31565242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10590187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27447719 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27447719 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31474753 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 22070868 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 22070868 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22070868 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8177458 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 8177458 — Safety Biomarker (SAF): Interleukin 1
Study 18337740 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 8993943 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8993943 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9793665 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31469508 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 31307833 — Surrogate Endpoint (SUR): Blood pressure
Study 31307833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10460064 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2135834 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31095683 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 31095683 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 31095683 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 23357198 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 9692657 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23747759 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 20884923 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7449282 — Surrogate Endpoint (SUR): Blood pressure
Study 28783382 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28783382 — Surrogate Endpoint (SUR): Blood pressure
Study 17876916 — Surrogate Endpoint (SUR): Serum potassium
Study 29329698 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 29329698 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 29329698 — Safety Biomarker (SAF): BDNF
Study 20215545 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20215545 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8872728 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24744309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24744309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24744309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22709418 — Surrogate Endpoint (SUR): Blood pressure
Study 9814616 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9814616 — Surrogate Endpoint (SUR): Blood pressure
Study 31369520 — Surrogate Endpoint (SUR): Blood pressure
Study 31369520 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25819196 — Surrogate Endpoint (SUR): Blood pressure
Study 9859958 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7542831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24830423 — Surrogate Endpoint (SUR): Serum sodium
Study 15579530 — Surrogate Endpoint (SUR): Serum creatinine
Study 28509078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29952617 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27129980 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22136317 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15285036 — Surrogate Endpoint (SUR): Serum potassium
Study 11594976 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD