TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27400997 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27400997 — Surrogate Endpoint (SUR): Blood pressure
Study 20534324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23751736 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23751736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10916520 — Surrogate Endpoint (SUR): Blood pressure
Study 10916520 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10916520 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3895595 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26814686 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20038728 — Predictive Biomarker (PRD): Hormone receptor
Study 19100066 — Surrogate Endpoint (SUR): Serum uric acid
Study 19100066 — Surrogate Endpoint (SUR): Blood pressure
Study 19100066 — Surrogate Endpoint (SUR): Serum potassium
Study 1635633 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 17992062 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11885548 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2197158 — Surrogate Endpoint (SUR): Blood pressure
Study 26098427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16897236 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 16897236 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30662004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25836351 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 23380979 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11212161 — Surrogate Endpoint (SUR): Bone mineral density
Study 19013107 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12709263 — Surrogate Endpoint (SUR): Blood pressure
Study 9096989 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19545680 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 19545680 — Surrogate Endpoint (SUR): Serum creatinine
Study 19545680 — Surrogate Endpoint (SUR): Serum uric acid
Study 19545680 — Safety Biomarker (SAF): Urinary total protein
Study 15087307 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15087307 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9676145 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2569322 — Surrogate Endpoint (SUR): Blood pressure
Study 28877715 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23440694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23440694 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23440694 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15900286 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7594122 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23816038 — Surrogate Endpoint (SUR): Blood pressure
Study 23816038 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20103547 — Surrogate Endpoint (SUR): Blood pressure
Study 20103547 — Surrogate Endpoint (SUR): Serum creatinine
Study 16385521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8865468 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 29432913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29432913 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 29432913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 29432913 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 12110626 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 30860682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22427534 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22427534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22427534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8737632 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28884306 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 28884306 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21649534 — Safety Biomarker (SAF): Urinary microalbumin
Study 21649534 — Surrogate Endpoint (SUR): Blood pressure
Study 20592125 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 12743558 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11783280 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 27430319 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 1346877 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31092643 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31092643 — Surrogate Endpoint (SUR): Blood pressure
Study 20542800 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15905672 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15839590 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 10616013 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10616013 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2055292 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6667808 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6667808 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 6667808 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 6667808 — Surrogate Endpoint (SUR): Blood pressure
Study 28572492 — Surrogate Endpoint (SUR): Blood pressure
Study 14997006 — Safety Biomarker (SAF): Interleukin 1
Study 14997006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31707465 — Surrogate Endpoint (SUR): Bone mineral density
Study 28153659 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18979150 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18979150 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2691694 — Surrogate Endpoint (SUR): Blood pressure
Study 21385483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19670953 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19670953 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19670953 — Surrogate Endpoint (SUR): Blood pressure
Study 11347755 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11347755 — Surrogate Endpoint (SUR): Blood pressure
Study 3540222 — Surrogate Endpoint (SUR): Blood pressure
Study 31197867 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 31197867 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 7778548 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 372609 — Surrogate Endpoint (SUR): Blood pressure
Study 30601976 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25552279 — Predictive Biomarker (PRD): SCAMP1 mRNA
Genes: SCAMP1; SCAMP
Study 25552279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14745707 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23838904 — Surrogate Endpoint (SUR): Pathological complete response
Study 3284218 — Surrogate Endpoint (SUR): Blood pressure
Study 17142216 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12629471 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1588374 — Surrogate Endpoint (SUR): Serum creatinine
Study 31476786 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 31510777 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10762562 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1348475 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 29164798 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 29164798 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23359361 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18206190 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30049724 — Surrogate Endpoint (SUR): Blood pressure
Study 30931835 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 29091568 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29091568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29091568 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29091568 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23806287 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21558575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21558575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12025735 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 7585298 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31927548 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27855643 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 1852516 — Surrogate Endpoint (SUR): Blood pressure
Study 28970213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22747420 — Surrogate Endpoint (SUR): Blood pressure
Study 20025832 — Surrogate Endpoint (SUR): Blood pressure
Study 8862090 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31047857 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27386745 — Surrogate Endpoint (SUR): Blood pressure
Study 22164957 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22164957 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22164957 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19930850 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 28662647 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 25125353 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24001251 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 28215835 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 21429706 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12706639 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 29735967 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26495694 — Predictive Biomarker (PRD): OPN1SW mRNA
Genes: OPN1SW; BCP
Study 12633548 — Surrogate Endpoint (SUR): Blood pressure
Study 12633548 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9209249 — Surrogate Endpoint (SUR): Blood pressure
Study 27155210 — Monitoring Biomarker (MOI): Procalcitonin
Study 24008587 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 24008587 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 24008587 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24008587 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 3894129 — Surrogate Endpoint (SUR): Blood pressure
Study 3894129 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18070144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18070144 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16480969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16480969 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 10729395 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 10729395 — Predictive Biomarker (PRD): PON2 mRNA
Genes: PON2
Study 10729395 — Predictive Biomarker (PRD): PON3 mRNA
Genes: PON3
Study 3840743 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3840743 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10234420 — Surrogate Endpoint (SUR): Blood pressure
Study 30528313 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 15819302 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9436937 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30075546 — Predictive Biomarker (PRD): PEBP1 mRNA
Genes: PEBP1; PBP; PEBP
Study 22923662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16466009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30036440 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27151024 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 19430043 — Surrogate Endpoint (SUR): Blood pressure
Study 22496275 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22496275 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22496275 — Surrogate Endpoint (SUR): Blood pressure
Study 21899544 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11070759 — Surrogate Endpoint (SUR): Blood pressure
Study 2865725 — Surrogate Endpoint (SUR): Blood pressure
Study 27488944 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27488944 — Surrogate Endpoint (SUR): Blood pressure
Study 22901886 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 16260891 — Surrogate Endpoint (SUR): Serum creatinine
Study 11382863 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 25488686 — Predictive Biomarker (PRD): Hormone receptor
Study 12790983 — Surrogate Endpoint (SUR): Blood pressure
Study 17356989 — Surrogate Endpoint (SUR): Blood pressure
Study 16238119 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12235690 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 30318240 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 25996273 — Surrogate Endpoint (SUR): Blood pressure
Study 19478547 — Surrogate Endpoint (SUR): Blood pressure
Study 15321699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11571244 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 2468877 — Surrogate Endpoint (SUR): Blood pressure
Study 26700184 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 26700184 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 26700184 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 21153402 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21153402 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 21153402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16385401 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21733953 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22414277 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 22414277 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 15839185 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15839185 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7856987 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29352831 — Surrogate Endpoint (SUR): Blood pressure
Study 29352831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16810542 — Surrogate Endpoint (SUR): Blood pressure
Study 31558549 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study 31558549 — Predictive Biomarker (PRD): HNF4A mRNA
Genes: HNF4A; HNF4; NR2A1; TCF14
Study 7534966 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 16365065 — Surrogate Endpoint (SUR): Blood pressure
Study 9372795 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 2861311 — Surrogate Endpoint (SUR): Blood pressure
Study 3121830 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9669456 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 7822066 — Surrogate Endpoint (SUR): Serum sodium
Study 29856651 — Surrogate Endpoint (SUR): Blood pressure
Study 12747344 — Surrogate Endpoint (SUR): Blood pressure
Study 30457088 — Predictive Biomarker (PRD): PKD2L1 mRNA
Genes: PKD2L1; PKD2L; PKDL; TRPP3
Study 22305836 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11811936 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27687824 — Predictive Biomarker (PRD): UCN3 mRNA
Genes: UCN3; SPC
Study 22388798 — Predictive Biomarker (PRD): SELE mRNA
Genes: SELE; ELAM1
Study 22388798 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22388798 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 22388798 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study 22388798 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 22388798 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 22388798 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22388798 — Predictive Biomarker (PRD): PDE4D mRNA
Genes: PDE4D; DPDE3
Study 22388798 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 17689196 — Surrogate Endpoint (SUR): Blood pressure
Study 19252247 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19834806 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30510410 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 17641457 — Surrogate Endpoint (SUR): Blood pressure
Study 11798458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11798458 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9716140 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 30971225 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19387330 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 30387043 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 8600865 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 6844301 — Surrogate Endpoint (SUR): Blood pressure
Study 24798657 — Surrogate Endpoint (SUR): Blood pressure
Study 20350135 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 20350135 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 16006728 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27325862 — Predictive Biomarker (PRD): Hormone receptor
Study 27325862 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24225325 — Surrogate Endpoint (SUR): Blood pressure
Study 18296421 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18296421 — Predictive Biomarker (PRD): Hormone receptor
Study 15756004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15756004 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25688638 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17712655 — Surrogate Endpoint (SUR): Bacterial count
Study 31848757 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31035478 — Surrogate Endpoint (SUR): Blood pressure
Study 18431498 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18431498 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 18431498 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 18431498 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27997877 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 27997877 — Surrogate Endpoint (SUR): Serum creatinine
Study 17955771 — Safety Biomarker (SAF): Hyaluronic acid
Study 15886538 — Surrogate Endpoint (SUR): Blood pressure
Study 8705091 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15632335 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15632335 — Surrogate Endpoint (SUR): Blood pressure
Study 15632335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10401916 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 7593425 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7593425 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23323897 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15975277 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15975277 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8912771 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 1655261 — Surrogate Endpoint (SUR): Blood pressure
Study 1655261 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30669665 — Surrogate Endpoint (SUR): Bone mineral density
Study 26873498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2