TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10496190 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9191512 — Surrogate Endpoint (SUR): Blood pressure
Study 30882751 — Predictive Biomarker (PRD): ERFE mRNA
Genes: ERFE; C1QTNF15; CTRP15; FAM132B
Study 20096223 — Surrogate Endpoint (SUR): Blood pressure
Study 31802616 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 17491259 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FasL mRNA
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 8214276 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 14648126 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11710785 — Surrogate Endpoint (SUR): Blood pressure
Study 30929011 — Surrogate Endpoint (SUR): Blood pressure
Study 24839241 — Surrogate Endpoint (SUR): Bone mineral density
Study 22153327 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 21450978 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18649012 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 17892986 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17892986 — Surrogate Endpoint (SUR): Serum creatinine
Study 9773717 — Surrogate Endpoint (SUR): Blood pressure
Study 29292264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29292264 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23571166 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22662132 — Predictive Biomarker (PRD): SHC1 mRNA
Genes: SHC1; SHC; SHCA
Study 22662132 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31706099 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21605732 — Surrogate Endpoint (SUR): Bone mineral density
Study 15305885 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27500639 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27500639 — Safety Biomarker (SAF): Preexisting antibody
Study 24377454 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24377454 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24377454 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24377454 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22592096 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18678155 — Surrogate Endpoint (SUR): Blood pressure
Study 10367592 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6342357 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 20202514 — Surrogate Endpoint (SUR): Blood pressure
Study 27803047 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 27803047 — Safety Biomarker (SAF): Reactive oxygen species
Study 27803047 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25136550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17692642 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15881482 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15881482 — Surrogate Endpoint (SUR): Blood pressure
Study 7499684 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7499684 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 7499684 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15271706 — Surrogate Endpoint (SUR): Blood pressure
Study 24786514 — Surrogate Endpoint (SUR): Bone mineral density
Study 18044282 — Surrogate Endpoint (SUR): Blood pressure
Study 7720758 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29929537 — Surrogate Endpoint (SUR): Blood pressure
Study 1333781 — Surrogate Endpoint (SUR): Blood pressure
Study 27452372 — Surrogate Endpoint (SUR): Blood pressure
Study 22121923 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19723695 — Surrogate Endpoint (SUR): Blood pressure
Study 9667263 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 8138256 — Monitoring Biomarker (MOI): HBV DNA
Study 24570387 — Surrogate Endpoint (SUR): Blood pressure
Study 7015797 — Surrogate Endpoint (SUR): Blood pressure
Study 8497553 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30790724 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24521695 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 20653608 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 16710858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16710858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15273831 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25780462 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10438709 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 10438709 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17559729 — Surrogate Endpoint (SUR): Blood pressure
Study 15613407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15613407 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15613407 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15613407 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15613407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10101627 — Surrogate Endpoint (SUR): Blood pressure
Study 19670975 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17443369 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 17443369 — Surrogate Endpoint (SUR): Blood pressure
Study 24619865 — Surrogate Endpoint (SUR): Blood pressure
Study 14557561 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 8631039 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1687407 — Surrogate Endpoint (SUR): Blood pressure
Study 30497093 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 14984727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14984727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14984727 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11590517 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30945740 — Surrogate Endpoint (SUR): Blood pressure
Study 23190794 — Surrogate Endpoint (SUR): Blood pressure
Study 23190794 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 1740938 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 23713245 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15185466 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12047395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12047395 — Surrogate Endpoint (SUR): Bone mineral density
Study 8172113 — Surrogate Endpoint (SUR): Blood pressure
Study 29082824 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 29082824 — Predictive Biomarker (PRD): MZB1 mRNA
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 17375982 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 17375982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17375982 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16045526 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 7788826 — Surrogate Endpoint (SUR): Blood pressure
Study 25714016 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 9176645 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8222166 — Surrogate Endpoint (SUR): Blood pressure
Study 8222166 — Surrogate Endpoint (SUR): Serum creatinine
Study 2871333 — Surrogate Endpoint (SUR): Blood pressure
Study 20624511 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16036503 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 12585170 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9312759 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25006770 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 12777952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 12777952 — Surrogate Endpoint (SUR): Blood pressure
Study 9843104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9843104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3517250 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29908669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29908669 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 26527782 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 26135348 — Surrogate Endpoint (SUR): Blood pressure
Study 14578367 — Surrogate Endpoint (SUR): Blood pressure
Study 11445478 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19900054 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 15570922 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 9311544 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28938325 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 23797810 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20820174 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 28159703 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 21601197 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21601197 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19751797 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19751797 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 12661911 — Surrogate Endpoint (SUR): Blood pressure
Study 1363508 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 1363508 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 25499341 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1899852 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30252057 — Surrogate Endpoint (SUR): Serum testosterone
Study 29176264 — Safety Biomarker (SAF): Hyaluronic acid
Study 19066934 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 19066934 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17909376 — Surrogate Endpoint (SUR): Blood pressure
Study 10980585 — Surrogate Endpoint (SUR): Blood pressure
Study 27845859 — Surrogate Endpoint (SUR): Bone mineral density
Study 12859696 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12859696 — Surrogate Endpoint (SUR): Blood pressure
Study 9352040 — Surrogate Endpoint (SUR): Bone mineral density
Study 26179891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12142559 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11981006 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10386509 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10386509 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21775558 — Surrogate Endpoint (SUR): Blood pressure
Study 9416721 — Surrogate Endpoint (SUR): Blood pressure
Study 8495702 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30035621 — Surrogate Endpoint (SUR): Bone mineral density
Study 26142300 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 12655445 — Surrogate Endpoint (SUR): Plasma methotrexate
Study 11078293 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 1596307 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29489895 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 27009101 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 17980884 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 17980884 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 16226024 — Surrogate Endpoint (SUR): Serum potassium
Study 16226024 — Surrogate Endpoint (SUR): Blood pressure
Study 7480566 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30835152 — Safety Biomarker (SAF): BDNF
Study 19724023 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19724023 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8402658 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 8684872 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 1516602 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 6408669 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24845183 — Surrogate Endpoint (SUR): Blood pressure
Study 18029338 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21749017 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1763796 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 6130077 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 23197976 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23197976 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16806875 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9871843 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2398244 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 24389597 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12110024 — Safety Biomarker (SAF): Reactive oxygen species
Study 8998247 — Surrogate Endpoint (SUR): Blood pressure
Study 15385735 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29244528 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29244528 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29244528 — Predictive Biomarker (PRD): Hormone receptor
Study 26630680 — Safety Biomarker (SAF): MTHFR
Study 19026303 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19026303 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19026303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16140027 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31754882 — Surrogate Endpoint (SUR): Serum uric acid
Study 25249405 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25249405 — Surrogate Endpoint (SUR): Blood pressure
Study 25249405 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21263343 — Surrogate Endpoint (SUR): Blood pressure
Study 11479164 — Surrogate Endpoint (SUR): Blood pressure
Study 20010618 — Surrogate Endpoint (SUR): Blood pressure
Study 9240887 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 31529406 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 19633827 — Surrogate Endpoint (SUR): Blood pressure
Study 8491068 — Surrogate Endpoint (SUR): Blood pressure
Study 7785682 — Surrogate Endpoint (SUR): Blood pressure
Study 31882564 — Predictive Biomarker (PRD): DLGAP2 mRNA
Genes: DLGAP2
Study 15133343 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 26599219 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26599219 — Surrogate Endpoint (SUR): Blood pressure
Study 26599219 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22371898 — Surrogate Endpoint (SUR): Blood pressure
Study 17355729 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17355729 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10521382 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 20454993 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 17363405 — Surrogate Endpoint (SUR): Blood pressure
Study 10226245 — Surrogate Endpoint (SUR): Blood pressure
Study 31496244 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28321001 — Surrogate Endpoint (SUR): Blood pressure
Study 26445302 — Surrogate Endpoint (SUR): Serum creatinine
Study 21538174 — Surrogate Endpoint (SUR): Blood pressure
Study 10524688 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 24300751 — Surrogate Endpoint (SUR): Blood pressure
Study 22705428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15842138 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15842138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15842138 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 15842138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12578487 — Surrogate Endpoint (SUR): Serum creatinine
Study 18400939 — Surrogate Endpoint (SUR): Bone mineral density
Study 18400939 — Surrogate Endpoint (SUR): Serum creatinine
Study 8567042 — Surrogate Endpoint (SUR): Blood pressure
Study 22925832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22925832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15568149 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 15568149 — Predictive Biomarker (PRD): TET1 mRNA
Genes: TET1; CXXC6; KIAA1676; LCX
Study 7527327 — Safety Biomarker (SAF): DRD2
Study 31659803 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 29868915 — Surrogate Endpoint (SUR): Blood pressure
Study 29868915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24056269 — Surrogate Endpoint (SUR): Blood pressure
Study 20739447 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18288087 — Predictive Biomarker (PRD): PDE4D mRNA
Genes: PDE4D; DPDE3
Study 18288087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23379539 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 23379539 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22204724 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19367154 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15247960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15247960 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 30717153 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30717153 — Safety Biomarker (SAF): BDNF
Study 25961136 — Surrogate Endpoint (SUR): Bone mineral density
Study 22613418 — Surrogate Endpoint (SUR): Serum potassium
Study 11861354 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28575534 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28575534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28575534 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19376321 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 24727254 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24727254 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18565801 — Surrogate Endpoint (SUR): Blood pressure
Study 11919122 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 11919122 — Surrogate Endpoint (SUR): Blood pressure
Study 2035280 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7038858 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 31276165 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27559855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8877075 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8877075 — Surrogate Endpoint (SUR): Blood pressure
Study 31146701 — Surrogate Endpoint (SUR): Serum creatinine
Study 26251312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17493194 — Surrogate Endpoint (SUR): Bone mineral density
Study 12099976 — Surrogate Endpoint (SUR): Blood pressure
Study 14602361 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 24879494 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 24879494 — Surrogate Endpoint (SUR): Blood pressure
Study 16280447 — Surrogate Endpoint (SUR): Bone mineral density
Study 12123334 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11498911 — Surrogate Endpoint (SUR): Serum creatinine
Study 9691864 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9691864 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29231344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26231378 — Surrogate Endpoint (SUR): Bone mineral density
Study 14623801 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP