TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04122833 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04406636 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01863134 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00219128 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02386943 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04014205 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00601861 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study NCT01007695 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT01007695 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT01007695 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01007695 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT03724201 — Predictive Biomarker (PRD): UCHL1 mRNA
Genes: UCHL1
Study NCT03724201 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02224365 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01826500 — Predictive Biomarker (PRD): ITIH5 mRNA
Genes: ITIH5; KIAA1953; PP14776; UNQ311/PRO354
Study NCT03135678 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02213939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04626960 — Predictive Biomarker (PRD): ADRB3 mRNA
Genes: ADRB3; ADRB3R; B3AR
Study NCT04626960 — Predictive Biomarker (PRD): ROCK2 mRNA
Genes: ROCK2; KIAA0619
Study NCT00819845 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00819845 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT00819845 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04328129 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02388997 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT02730416 — Predictive Biomarker (PRD): EN1 mRNA
Genes: EN1
Study NCT03619395 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02509507 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00775281 — Predictive Biomarker (PRD): TACR1 mRNA
Genes: TACR1; NK1R; TAC1R
Study NCT03536039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00004864 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT01449773 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study NCT01449773 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study NCT01449773 — Predictive Biomarker (PRD): ACAT2 mRNA
Genes: ACAT2; ACTL
Study NCT01449773 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT03306888 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04510935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03281551 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04500236 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT04500236 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00933244 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03291613 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03738150 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03738150 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01749891 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04216082 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT04644432 — Predictive Biomarker (PRD): RHOH mRNA
Genes: RHOH; ARHH; TTF
Study NCT02762721 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT04049240 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00483925 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00483925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01470404 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT04000334 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01540578 — Predictive Biomarker (PRD): SH3PXD2A mRNA
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study NCT04913428 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02098161 — Predictive Biomarker (PRD): DIABLO mRNA
Genes: DIABLO; SMAC
Study NCT03329963 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00913393 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01920152 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01156168 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00907920 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04357964 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study NCT04357964 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study NCT04035096 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00533858 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01995552 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01665989 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00607854 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01812369 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT03926312 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04251975 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04299763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04299763 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT02014415 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00646204 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03721809 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study NCT02611167 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03692689 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04341480 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02063997 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00797992 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05919641 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT01558882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01558882 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02396953 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study NCT02177409 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01968577 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT03622177 — Predictive Biomarker (PRD): IL33 mRNA
Genes: IL33; C9orf26; IL1F11; NFHEV
Study NCT03683134 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02428920 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01437813 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study NCT03905421 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01470469 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01470469 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03535480 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03167489 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02396758 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00868673 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00482768 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02814097 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT00498433 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04852510 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03342170 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT01835249 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03493854 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03493854 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00170989 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00621829 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study NCT02827500 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01989702 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01846559 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04615325 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02748577 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT02153905 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT01546116 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03443232 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01237652 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03101475 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT02017132 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03829735 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05556213 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study NCT04563247 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02547220 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02551562 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02117063 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00638703 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT00869622 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03424525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01148953 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT02796807 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03779217 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02199431 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02199431 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04075409 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01414556 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00702130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01018459 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT01018459 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04225039 — Predictive Biomarker (PRD): TNFRSF18 mRNA
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study NCT04225039 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00559962 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT03497780 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03497780 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT01831310 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01831310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01831310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03985371 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study NCT02458443 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00584467 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT00703105 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00703105 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT00703105 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT02320344 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00677495 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study NCT00325806 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00325806 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03693339 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01486563 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT01486563 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT03279276 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04115358 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01205165 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT01205165 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04032756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00003694 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00003694 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04435327 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04182581 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04182581 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04520945 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00799617 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00799617 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01356823 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03837795 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT04916834 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04570683 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01513252 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03061539 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01516879 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00448266 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02684864 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study NCT01013415 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01013415 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02737202 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT00004031 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00437034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04143412 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00513695 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03717038 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00249301 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT04311398 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04247126 — Predictive Biomarker (PRD): CDK7 mRNA
Genes: CDK7; CAK; CAK1; CDKN7; MO15; STK1
Study NCT04247126 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04247126 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03484962 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT02205541 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT04313894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03305471 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT00519714 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00519714 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT00519714 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00519714 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01929564 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04048798 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02414555 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01152060 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00936078 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01384058 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03974100 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03337724 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT03337724 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study NCT03337724 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03337724 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03337724 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03337724 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03337724 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00773097 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT03023696 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT04522583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00920699 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03840343 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02593708 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03777124 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03324698 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04526470 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04526470 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT00125853 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04535128 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00574600 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study NCT03755232 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT04754685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04754685 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT03242252 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03678831 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02965053 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00576823 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study NCT00051051 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02320305 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT03989297 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03989297 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01654835 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03057145 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study NCT01501981 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT02059928 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02355392 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03166397 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04367467 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01516190 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT00519857 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01504334 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01990911 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03447977 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01823029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00145509 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT03722836 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT00707746 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03851614 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03149003 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study NCT00937638 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00129233 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00640757 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01690039 — Predictive Biomarker (PRD): ATP6V1B1 mRNA
Genes: ATP6V1B1; ATP6B1; VATB; VPP3
Study NCT01690039 — Predictive Biomarker (PRD): ATP6V0A4 mRNA
Genes: ATP6V0A4; ATP6N1B; ATP6N2
Study NCT03949075 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04024475 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT02804308 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00404599 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00404599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00404599 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00404599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00404599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00949598 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01078584 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01078584 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00077168 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1