TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18762502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19748858 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19748858 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 9043724 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 9043724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31761974 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 31761974 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 25693859 — Surrogate Endpoint (SUR): Blood pressure
Study 16615418 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 8860064 — Surrogate Endpoint (SUR): Blood pressure
Study 1298143 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 19479879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15094269 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11701687 — Surrogate Endpoint (SUR): Bone mineral density
Study 9771244 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 31028669 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 31028669 — Predictive Biomarker (PRD): PLCG2 mRNA
Genes: PLCG2
Study 18294485 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 7901064 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 31858113 — Predictive Biomarker (PRD): GRAMD2A mRNA
Genes: GRAMD2A; GRAMD2
Study 31858113 — Predictive Biomarker (PRD): LOXL1 mRNA
Genes: LOXL1; LOXL
Study 31858113 — Predictive Biomarker (PRD): HTR1B mRNA
Genes: HTR1B; HTR1DB
Study 31858113 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 31858113 — Predictive Biomarker (PRD): KIF25 mRNA
Genes: KIF25; KNSL3
Study 31858113 — Predictive Biomarker (PRD): SLC39A14 mRNA
Genes: SLC39A14; KIAA0062; ZIP14
Study 18585835 — Surrogate Endpoint (SUR): Serum creatinine
Study 23658423 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 21874260 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21874260 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12716812 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12716812 — Surrogate Endpoint (SUR): Blood pressure
Study 9679720 — Surrogate Endpoint (SUR): Blood pressure
Study 8004882 — Surrogate Endpoint (SUR): Blood pressure
Study 9425966 — Surrogate Endpoint (SUR): Blood pressure
Study 8236030 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24744165 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 26850449 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20648601 — Monitoring Biomarker (MOI): HBV DNA
Study 29555393 — Monitoring Biomarker (MOI): Procalcitonin
Study 29555393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29555393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16364838 — Surrogate Endpoint (SUR): Blood pressure
Study 10592855 — Surrogate Endpoint (SUR): Blood pressure
Study 8572837 — Surrogate Endpoint (SUR): Blood pressure
Study 6129886 — Surrogate Endpoint (SUR): Blood pressure
Study 24680587 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22031171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22031171 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14678347 — Surrogate Endpoint (SUR): Serum potassium
Study 14678347 — Surrogate Endpoint (SUR): Blood pressure
Study 12231083 — Surrogate Endpoint (SUR): Blood pressure
Study 9844955 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 9844955 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11855793 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11855793 — Surrogate Endpoint (SUR): Blood pressure
Study 2831525 — Surrogate Endpoint (SUR): Blood pressure
Study 10426835 — Surrogate Endpoint (SUR): Serum sodium
Study 2376246 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 2376246 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27930452 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27930452 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23368915 — Monitoring Biomarker (MOI): Procalcitonin
Study 23368915 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28630396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28630396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20932155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20932155 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 10843450 — Surrogate Endpoint (SUR): Blood pressure
Study 29948666 — Surrogate Endpoint (SUR): Serum creatinine
Study 29948666 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28629338 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8403573 — Surrogate Endpoint (SUR): Blood pressure
Study 30839013 — Surrogate Endpoint (SUR): Blood pressure
Study 28335886 — Surrogate Endpoint (SUR): Pathological complete response
Study 17554116 — Surrogate Endpoint (SUR): Serum creatinine
Study 12063011 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 7818160 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7818160 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29967948 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 26014321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 19554082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17719320 — Surrogate Endpoint (SUR): Serum creatinine
Study 8059623 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 3058043 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25403646 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25403646 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15284376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15284376 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 8039151 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12026536 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 31155392 — Surrogate Endpoint (SUR): Blood pressure
Study 3105747 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 3105747 — Surrogate Endpoint (SUR): Blood pressure
Study 22440371 — Surrogate Endpoint (SUR): Blood pressure
Study 12234955 — Surrogate Endpoint (SUR): Blood pressure
Study 6388901 — Surrogate Endpoint (SUR): Blood pressure
Study 22404145 — Surrogate Endpoint (SUR): Blood pressure
Study 21063110 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 17559697 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11535549 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9647497 — Safety Biomarker (SAF): 51Cr-EDTA
Study 9647497 — Surrogate Endpoint (SUR): Serum creatinine
Study 9647497 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20038402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15329902 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8117630 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2868337 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 22874424 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 14673758 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14673758 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8883267 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1517726 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 25205868 — Predictive Biomarker (PRD): CNGB3 mRNA
Genes: CNGB3
Study 25205868 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 20416132 — Predictive Biomarker (PRD): C1GALT1 mRNA
Genes: C1GALT1
Study 20416132 — Predictive Biomarker (PRD): GM2A mRNA
Genes: GM2A
Study 20416132 — Predictive Biomarker (PRD): HDGF mRNA
Genes: HDGF; HMG1L2
Study 20416132 — Predictive Biomarker (PRD): SERPINB9 mRNA
Genes: SERPINB9; PI9
Study 30595080 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 30595080 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 27352329 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8751024 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24255071 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24255071 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21353720 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19210693 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19210693 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17944734 — Surrogate Endpoint (SUR): Serum creatinine
Study 17944734 — Surrogate Endpoint (SUR): Blood pressure
Study 15083442 — Surrogate Endpoint (SUR): Blood pressure
Study 29948282 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 29948282 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 28578682 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 12174103 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 9798075 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 2704503 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2704503 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28452716 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23258626 — Surrogate Endpoint (SUR): Serum testosterone
Study 23258626 — Surrogate Endpoint (SUR): Bone mineral density
Study 9554045 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23712737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23712737 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23712737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9695991 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 9695991 — Predictive Biomarker (PRD): MUC6 mRNA
Genes: MUC6
Study 8016587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20413299 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20413299 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20413299 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 20413299 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20413299 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 12239234 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10065895 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 31101920 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 21988649 — Surrogate Endpoint (SUR): Blood pressure
Study 23356580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10523001 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 8619701 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26031572 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15210658 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 15210658 — Predictive Biomarker (PRD): SAT2 mRNA
Genes: SAT2; SSAT2
Study 8305166 — Surrogate Endpoint (SUR): Blood pressure
Study 22459388 — Surrogate Endpoint (SUR): Blood pressure
Study 22459388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22459388 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22459388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22459388 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18713490 — Safety Biomarker (SAF): Hyaluronic acid
Study 11321442 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11321442 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11321442 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17468524 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 2112516 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29849514 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 24026037 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 24026037 — Surrogate Endpoint (SUR): Blood pressure
Study 19040336 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 19040336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15867169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15867169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15867169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11436193 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19589242 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19589242 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 30859680 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 26460279 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 23181738 — Surrogate Endpoint (SUR): Blood pressure
Study 2578012 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 21095263 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18692886 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12610044 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 24616337 — Surrogate Endpoint (SUR): Blood pressure
Study 19823185 — Surrogate Endpoint (SUR): Blood pressure
Study 8934467 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 17634169 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17634169 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17634169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14981523 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 8033372 — Predictive Biomarker (PRD): ABL2 mRNA
Genes: ABL2; ABLL; ARG
Study 17611730 — Surrogate Endpoint (SUR): Blood pressure
Study 28499749 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 14764389 — Surrogate Endpoint (SUR): Blood pressure
Study 7710569 — Surrogate Endpoint (SUR): Serum calcium
Study 2551520 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23433094 — Predictive Biomarker (PRD): TMPRSS6 mRNA
Genes: TMPRSS6; UNQ354/PRO618
Study 23433094 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 23433094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30127510 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30127510 — Safety Biomarker (SAF): BDNF
Study 27517656 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27517656 — Surrogate Endpoint (SUR): Blood pressure
Study 10989734 — Surrogate Endpoint (SUR): Blood pressure
Study 20019680 — Surrogate Endpoint (SUR): Blood pressure
Study 18520796 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30644260 — Surrogate Endpoint (SUR): Bone mineral density
Study 18065586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3083919 — Surrogate Endpoint (SUR): Blood pressure
Study 31153846 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 28168204 — Surrogate Endpoint (SUR): Blood pressure
Study 23922647 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 23922647 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 19298459 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17914131 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 7484859 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1968323 — Surrogate Endpoint (SUR): Blood pressure
Study 7295463 — Surrogate Endpoint (SUR): Blood pressure
Study 19267352 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19267352 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19267352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 19267352 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 11725730 — Surrogate Endpoint (SUR): Bone mineral density
Study 11725730 — Surrogate Endpoint (SUR): Serum calcium
Study 24797423 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 20803423 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 20803423 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15897360 — Surrogate Endpoint (SUR): Blood pressure
Study 12324674 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12324674 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11077510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8783998 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1536437 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26050706 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 26050706 — Surrogate Endpoint (SUR): Serum creatinine
Study 22275504 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18341602 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 16466061 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15637686 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24606242 — Surrogate Endpoint (SUR): Blood pressure
Study 11454015 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11454015 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11454015 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9683392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24140602 — Predictive Biomarker (PRD): SHD mRNA
Genes: SHD
Study 24140602 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17159063 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24492945 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22614886 — Predictive Biomarker (PRD): GMDS mRNA
Genes: GMDS
Study 31606042 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 23741965 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 23741965 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 18987654 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 19351876 — Surrogate Endpoint (SUR): Blood pressure
Study 17168667 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 15526247 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 15526247 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15526247 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8366821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8366821 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 26537570 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 20086017 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16820546 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 15921057 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11797179 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31000477 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9407424 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9407424 — Surrogate Endpoint (SUR): Serum creatinine
Study 7705386 — Surrogate Endpoint (SUR): Blood pressure
Study 18471327 — Surrogate Endpoint (SUR): Blood pressure
Study 15767619 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10988188 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8772549 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27281490 — Safety Biomarker (SAF): Reactive oxygen species
Study 8053578 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8053578 — Surrogate Endpoint (SUR): Blood pressure
Study 23599435 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 23599435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20533022 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 15962678 — Surrogate Endpoint (SUR): Blood pressure
Study 1755551 — Surrogate Endpoint (SUR): Blood pressure