TrialPanorama/TrialPanorama-database huggingface dataset:
Study 798591 — Surrogate Endpoint (SUR): Serum uric acid
Study 23103035 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 28193568 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 28193568 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 25815420 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17227571 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 17227571 — Surrogate Endpoint (SUR): Blood pressure
Study 16083171 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 2418304 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2418304 — Surrogate Endpoint (SUR): Blood pressure
Study 22824921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22824921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21448918 — Surrogate Endpoint (SUR): Bone mineral density
Study 16813472 — Surrogate Endpoint (SUR): Bone mineral density
Study 30362819 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22352291 — Surrogate Endpoint (SUR): Blood pressure
Study 10517036 — Surrogate Endpoint (SUR): Blood pressure
Study 1633070 — Surrogate Endpoint (SUR): Serum testosterone
Study 6428911 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 24568910 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31407810 — Safety Biomarker (SAF): Human leucocyte antigen
Study 31407810 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19011931 — Surrogate Endpoint (SUR): Blood pressure
Study 19011931 — Predictive Biomarker (PRD): NE
Study 3310745 — Surrogate Endpoint (SUR): Blood pressure
Study 3310745 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22323747 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 15983534 — Surrogate Endpoint (SUR): Blood pressure
Study 7795311 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 7795311 — Surrogate Endpoint (SUR): Blood pressure
Study 7795311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8443028 — Surrogate Endpoint (SUR): Blood pressure
Study 27187447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11380832 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11380832 — Surrogate Endpoint (SUR): Blood pressure
Study 24679247 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19684008 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19684008 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 19684008 — Safety Biomarker (SAF): Reactive oxygen species
Study 18662492 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18662492 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 12666950 — Surrogate Endpoint (SUR): Bone mineral density
Study 6338251 — Surrogate Endpoint (SUR): Serum creatinine
Study 21822058 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 8325311 — Surrogate Endpoint (SUR): Blood pressure
Study 8325311 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28333353 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28344345 — Safety Biomarker (SAF): miR-15a
Genes: MIR15A
Study 28344345 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-34a
Genes: MIR34A
Study 28344345 — Predictive Biomarker (PRD): miR-106a
Genes: MIR106A
Study 28344345 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 28344345 — Predictive Biomarker (PRD): miR-135b
Genes: MIR135B
Study 28344345 — Safety Biomarker (SAF): miR-206
Genes: MIR206
Study 28344345 — Predictive Biomarker (PRD): miR-106b
Genes: MIR106B
Study 24248687 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20603436 — Predictive Biomarker (PRD): ACRC mRNA
Genes: GCNA; ACRC
Study 15480130 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11782693 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 26413789 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24535360 — Surrogate Endpoint (SUR): Blood pressure
Study 20584655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17072055 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 24764640 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20148906 — Surrogate Endpoint (SUR): Bone mineral density
Study 6128546 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27528117 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30630782 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 21196929 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 21196929 — Surrogate Endpoint (SUR): Blood pressure
Study 16076919 — Surrogate Endpoint (SUR): Bone mineral density
Study 27918731 — Surrogate Endpoint (SUR): Blood pressure
Study 9443710 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31628085 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 23652578 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 2443087 — Surrogate Endpoint (SUR): Blood pressure
Study 18811573 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18811573 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 16043828 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 16043828 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30579372 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30579372 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28560779 — Surrogate Endpoint (SUR): Blood pressure
Study 16041450 — Surrogate Endpoint (SUR): Blood pressure
Study 9489597 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 9489597 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 8973778 — Surrogate Endpoint (SUR): Blood pressure
Study 1325520 — Surrogate Endpoint (SUR): Blood pressure
Study 27598983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17344509 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12095492 — Surrogate Endpoint (SUR): Bone mineral density
Study 24519863 — Surrogate Endpoint (SUR): Blood pressure
Study 24519863 — Surrogate Endpoint (SUR): Serum uric acid
Study 22067666 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 22067666 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22067666 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 22067666 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16418138 — Surrogate Endpoint (SUR): Blood pressure
Study 16418138 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31587090 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 31587090 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 20385930 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17371829 — Surrogate Endpoint (SUR): Serum creatinine
Study 28830669 — Surrogate Endpoint (SUR): Blood pressure
Study 25252593 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15309209 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15309209 — Surrogate Endpoint (SUR): Blood pressure
Study 17598653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12059914 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 1259126 — Surrogate Endpoint (SUR): Blood pressure
Study 31864809 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 23908084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21983214 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 7845792 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 29292054 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21317794 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 21317794 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 21317794 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21317794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21317794 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9062488 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7934009 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7934009 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 27544607 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25535691 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29686027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29686027 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 29686027 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 29686027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24102806 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20884874 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 20884874 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16756147 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 16756147 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27406897 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 24192055 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18206038 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16366235 — Surrogate Endpoint (SUR): Blood pressure
Study 8549941 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7701171 — Surrogate Endpoint (SUR): Serum calcium
Study 31706719 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31706719 — Predictive Biomarker (PRD): Hormone receptor
Study 21174209 — Surrogate Endpoint (SUR): Blood pressure
Study 18806550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18806550 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 18806550 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10827334 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 8624759 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29500848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29500848 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29500848 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26854355 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 17367769 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 17367769 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31659794 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16555157 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 16555157 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24158761 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 8620970 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28463879 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23148565 — Safety Biomarker (SAF): Reactive oxygen species
Study 9313664 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 30261896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30261896 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 30261896 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30261896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25919120 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 19460761 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 19460761 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 19460761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19460761 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 19460761 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16826487 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16826487 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10890632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10890632 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1574014 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27912954 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10680028 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18714251 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18714251 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1609997 — Surrogate Endpoint (SUR): Blood pressure
Study 3723795 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22878491 — Surrogate Endpoint (SUR): Blood pressure
Study 20049465 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 3300241 — Surrogate Endpoint (SUR): Blood pressure
Study 27197908 — Surrogate Endpoint (SUR): Blood pressure
Study 27197908 — Surrogate Endpoint (SUR): Serum creatinine
Study 18516353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18516353 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18516353 — Surrogate Endpoint (SUR): Serum calcium
Study 10539777 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 28949260 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 28949260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28949260 — Safety Biomarker (SAF): Interleukin 1
Study 28949260 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15116352 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8249842 — Surrogate Endpoint (SUR): Blood pressure
Study 27367521 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27367521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15639633 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 9445198 — Safety Biomarker (SAF): Interleukin 1
Study 9445198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9445198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7573232 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 6670732 — Surrogate Endpoint (SUR): Blood pressure
Study 6670732 — Surrogate Endpoint (SUR): Serum potassium
Study 15115831 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29417495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29417495 — Surrogate Endpoint (SUR): Serum creatinine
Study 18248281 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 16569261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8624266 — Surrogate Endpoint (SUR): Serum calcium
Study 29961573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19484982 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7592245 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2547139 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 27190095 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20889387 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 12548313 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12548313 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31267688 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30372645 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 22403884 — Surrogate Endpoint (SUR): Bone mineral density
Study 10473080 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 25146063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9133941 — Surrogate Endpoint (SUR): Bone mineral density
Study 12576812 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12576812 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8784742 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20558037 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15962224 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26743348 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26743348 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 18089905 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18089905 — Surrogate Endpoint (SUR): Blood pressure
Study 31638498 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 30092876 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 30092876 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25133164 — Surrogate Endpoint (SUR): Blood pressure
Study 22417778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22417778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20966122 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 14766942 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 28489637 — Surrogate Endpoint (SUR): Blood pressure
Study 25491493 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 25491493 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 20798655 — Surrogate Endpoint (SUR): Bone mineral density
Study 12956861 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12956861 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12956861 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19589539 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 19589539 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19589539 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 12575371 — Safety Biomarker (SAF): Hyaluronic acid
Study 22490715 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 17892610 — Surrogate Endpoint (SUR): Blood pressure
Study 12364444 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6351586 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26135553 — Surrogate Endpoint (SUR): Blood pressure
Study 19388505 — Surrogate Endpoint (SUR): Blood pressure
Study 9554567 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21761706 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 19258920 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 16961676 — Surrogate Endpoint (SUR): Blood pressure
Study 17693905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17693905 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12040440 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 12040440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25564797 — Safety Biomarker (SAF): Hyaluronic acid
Study 9836523 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 2680230 — Surrogate Endpoint (SUR): Blood pressure
Study 19809308 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 19809308 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2642658 — Surrogate Endpoint (SUR): Blood pressure
Study 938161 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30763457 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30763457 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22171802 — Surrogate Endpoint (SUR): Blood pressure
Study 2907080 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21608219 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 21608219 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10653873 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8218004 — Surrogate Endpoint (SUR): Blood pressure
Study 26945918 — Safety Biomarker (SAF): Hyaluronic acid
Study 23990572 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 23990572 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 19783599 — Safety Biomarker (SAF): Human leucocyte antigen