TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20950383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18199105 — Surrogate Endpoint (SUR): Blood pressure
Study 3320720 — Surrogate Endpoint (SUR): Blood pressure
Study 3320720 — Surrogate Endpoint (SUR): Serum uric acid
Study 3320720 — Surrogate Endpoint (SUR): Serum potassium
Study 8092089 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15496274 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26400262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26400262 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26400262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21312265 — Surrogate Endpoint (SUR): Bone mineral density
Study 12463387 — Surrogate Endpoint (SUR): Blood pressure
Study 26452162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26452162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22259246 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17230434 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 8110919 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 3333521 — Surrogate Endpoint (SUR): Blood pressure
Study 7756098 — Surrogate Endpoint (SUR): Blood pressure
Study 30271161 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20810155 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 17932223 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 12786704 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 10985709 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 7884505 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20460711 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 29743826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24740596 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23036993 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 23036993 — Surrogate Endpoint (SUR): Blood pressure
Study 18457257 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 18457257 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 18457257 — Predictive Biomarker (PRD): SYNM mRNA
Genes: SYNM; DMN; KIAA0353; SYN
Study 9831696 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9831696 — Surrogate Endpoint (SUR): Blood pressure
Study 22014101 — Surrogate Endpoint (SUR): Serum calcium
Study 15181050 — Surrogate Endpoint (SUR): Blood pressure
Study 9027779 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 9027779 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 8391513 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 8391513 — Surrogate Endpoint (SUR): Blood pressure
Study 24667035 — Surrogate Endpoint (SUR): Blood pressure
Study 18052708 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 12046033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12046033 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12046033 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11783153 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 11783153 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11783153 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7825526 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 396673 — Surrogate Endpoint (SUR): Blood pressure
Study 30146268 — Predictive Biomarker (PRD): LUM mRNA
Genes: LUM; LDC; SLRR2D
Study 21953763 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 18187214 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18187214 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15845678 — Surrogate Endpoint (SUR): Blood pressure
Study 12692006 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 6759144 — Surrogate Endpoint (SUR): Blood pressure
Study 24611484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24611484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24611484 — Safety Biomarker (SAF): Hyaluronic acid
Study 17239062 — Surrogate Endpoint (SUR): Blood pressure
Study 9585772 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2172376 — Surrogate Endpoint (SUR): Blood pressure
Study 629073 — Surrogate Endpoint (SUR): Blood pressure
Study 30548890 — Predictive Biomarker (PRD): DSE mRNA
Genes: DSE; SART2
Study 28541285 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 21113789 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21113789 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21113789 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 16772250 — Surrogate Endpoint (SUR): Blood pressure
Study 3038254 — Surrogate Endpoint (SUR): Blood pressure
Study 18487911 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10321445 — Surrogate Endpoint (SUR): Blood pressure
Study 2691818 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21062392 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 31364232 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31556273 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25769495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31987331 — Predictive Biomarker (PRD): GDF9 mRNA
Genes: GDF9
Study 31987331 — Predictive Biomarker (PRD): PDSS2 mRNA
Genes: PDSS2; C6orf210; DLP1
Study 17911541 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8046120 — Surrogate Endpoint (SUR): Blood pressure
Study 26969308 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 22739369 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study 22739369 — Surrogate Endpoint (SUR): Blood pressure
Study 10670114 — Surrogate Endpoint (SUR): Serum potassium
Study 24698485 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11739089 — Predictive Biomarker (PRD): AWAT2 mRNA
Genes: AWAT2; DC4; DGAT2L4; MFAT; WS
Study 2285609 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 30280324 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 18347178 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 18347178 — Predictive Biomarker (PRD): Hormone receptor
Study 19918017 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17092654 — Safety Biomarker (SAF): IL-6 and IL-10
Study 31851082 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 24898857 — Predictive Biomarker (PRD): ATAD2 mRNA
Genes: ATAD2; L16; PRO2000
Study 14720530 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 14720530 — Predictive Biomarker (PRD): GAPDH mRNA
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 8206564 — Surrogate Endpoint (SUR): Serum potassium
Study 8150546 — Surrogate Endpoint (SUR): Blood pressure
Study 27413042 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27413042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12814444 — Surrogate Endpoint (SUR): Blood pressure
Study 2058867 — Surrogate Endpoint (SUR): Blood pressure
Study 2058867 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25596881 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25596881 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23980876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21378141 — Surrogate Endpoint (SUR): Blood pressure
Study 6185089 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31705750 — Surrogate Endpoint (SUR): Blood pressure
Study 24869931 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15329918 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 11060829 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26458258 — Predictive Biomarker (PRD): ADH1B mRNA
Genes: ADH1B; ADH2
Study 26458258 — Surrogate Endpoint (SUR): Blood pressure
Study 26458258 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18853428 — Surrogate Endpoint (SUR): Bone mineral density
Study 15240647 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3130925 — Surrogate Endpoint (SUR): Serum calcium
Study 22852760 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22852760 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 9440748 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 9440748 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2684073 — Surrogate Endpoint (SUR): Blood pressure
Study 15242424 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1655350 — Surrogate Endpoint (SUR): Serum calcium
Study 31529492 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 27921413 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 16574438 — Predictive Biomarker (PRD): GYPC mRNA
Genes: GYPC; GLPC; GPC
Study 1359211 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31550290 — Predictive Biomarker (PRD): FMR1
Genes: FMRP; FRAXA; MGC87458
Study 27624603 — Surrogate Endpoint (SUR): Serum sodium
Study 27624603 — Surrogate Endpoint (SUR): Serum potassium
Study 7795830 — Surrogate Endpoint (SUR): Blood pressure
Study 359140 — Surrogate Endpoint (SUR): Blood pressure
Study 11204665 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 11204665 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8318783 — Predictive Biomarker (PRD): TIMM8A mRNA
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 8318783 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 25062396 — Surrogate Endpoint (SUR): Blood pressure
Study 18799820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18799820 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18799820 — Surrogate Endpoint (SUR): Blood pressure
Study 18799820 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18799820 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10480471 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10480471 — Surrogate Endpoint (SUR): Blood pressure
Study 28728281 — Surrogate Endpoint (SUR): Blood pressure
Study 6871776 — Surrogate Endpoint (SUR): Blood pressure
Study 6871776 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21909730 — Surrogate Endpoint (SUR): Bone mineral density
Study 9793810 — Surrogate Endpoint (SUR): Blood pressure
Study 11527130 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11527130 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 11527130 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 11527130 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 11527130 — Surrogate Endpoint (SUR): Blood pressure
Study 27676149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31669625 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31669625 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22463757 — Predictive Biomarker (PRD): TRIL mRNA
Genes: TRIL; KIAA0644
Study 19119028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19119028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9671379 — Surrogate Endpoint (SUR): Serum sodium
Study 12764908 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7586434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17005527 — Surrogate Endpoint (SUR): Serum calcium
Study 17005527 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17005527 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 2956957 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 25365133 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 20147570 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 20147570 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17126653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17126653 — Surrogate Endpoint (SUR): Blood pressure
Study 23428009 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 30782687 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10480514 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 2187384 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 29882203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29882203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29882203 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29882203 — Predictive Biomarker (PRD): VCAM1 mRNA
Genes: VCAM1
Study 29882203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16533939 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16533939 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10840011 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10840011 — Surrogate Endpoint (SUR): Blood pressure
Study 1614253 — Surrogate Endpoint (SUR): Blood pressure
Study 30833130 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22773591 — Surrogate Endpoint (SUR): Bone mineral density
Study 17919105 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17919105 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17919105 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28385131 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25172378 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17908370 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 30916463 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 7525446 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 7525446 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29861487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15782425 — Surrogate Endpoint (SUR): Blood pressure
Study 12404882 — Surrogate Endpoint (SUR): Blood pressure
Study 12404882 — Surrogate Endpoint (SUR): Serum creatinine
Study 7582380 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 2348453 — Surrogate Endpoint (SUR): Blood pressure
Study 29184389 — Monitoring Biomarker (MOI): HBV DNA
Study 24592747 — Predictive Biomarker (PRD): TERF1 mRNA
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study 14962945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9856369 — Surrogate Endpoint (SUR): Blood pressure
Study 9856369 — Surrogate Endpoint (SUR): Serum potassium
Study 20168213 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 20168213 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 15590711 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12085418 — Surrogate Endpoint (SUR): Blood pressure
Study 30076458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30076458 — Surrogate Endpoint (SUR): Serum calcium
Study 19020851 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 10856317 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 10856317 — Safety Biomarker (SAF): Reactive oxygen species
Study 9104901 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25286691 — Surrogate Endpoint (SUR): Serum potassium
Study 10652037 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10652037 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 10652037 — Surrogate Endpoint (SUR): Blood pressure
Study 10652037 — Surrogate Endpoint (SUR): Serum potassium
Study 28237635 — Surrogate Endpoint (SUR): Blood pressure
Study 19680681 — Surrogate Endpoint (SUR): Blood pressure
Study 9447478 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29788487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29788487 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28902705 — Surrogate Endpoint (SUR): Bone mineral density
Study 25411292 — Predictive Biomarker (PRD): PRKN mRNA
Genes: PRKN; PARK2
Study 25411292 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25411292 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 16806873 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16806873 — Surrogate Endpoint (SUR): Blood pressure
Study 12040528 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7719244 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 29349976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25440999 — Surrogate Endpoint (SUR): Blood pressure
Study 19496776 — Surrogate Endpoint (SUR): Blood pressure
Study 10856892 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3510282 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 3510282 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23102995 — Surrogate Endpoint (SUR): Blood pressure
Study 23102995 — Surrogate Endpoint (SUR): Serum creatinine
Study 20634749 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20634749 — Surrogate Endpoint (SUR): Blood pressure
Study 18607829 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28389389 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 28389389 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 28389389 — Predictive Biomarker (PRD): TRPV4 mRNA
Genes: TRPV4; VRL2; VROAC
Study 28389389 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 28389389 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 15503074 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11416677 — Surrogate Endpoint (SUR): Blood pressure
Study 29696963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29696963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29696963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26796240 — Surrogate Endpoint (SUR): Bone mineral density
Study 23365129 — Surrogate Endpoint (SUR): Serum calcium
Study 27445627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24670520 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23457387 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23457387 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 23457387 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 23457387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21930598 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 21930598 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21930598 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21930598 — Safety Biomarker (SAF): Reactive oxygen species
Study 21930598 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15173128 — Surrogate Endpoint (SUR): Blood pressure
Study 12117291 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12117291 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25477424 — Surrogate Endpoint (SUR): Blood pressure
Study 19517675 — Surrogate Endpoint (SUR): Blood pressure
Study 16997310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16997310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16997310 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 16997310 — Safety Biomarker (SAF): Interleukin 1
Study 16997310 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26523993 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16180033 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 16303728 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16303728 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2131793 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 773486 — Surrogate Endpoint (SUR): Blood pressure
Study 2239886 — Surrogate Endpoint (SUR): Serum triglycerides