TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7950448 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15820324 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 27956829 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 20435239 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20435239 — Surrogate Endpoint (SUR): Blood pressure
Study 18307460 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 18307460 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 18307460 — Surrogate Endpoint (SUR): Blood pressure
Study 16120227 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10197378 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31005677 — Surrogate Endpoint (SUR): Blood pressure
Study 11157561 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 11157561 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 3048792 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 16803851 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16803851 — Safety Biomarker (SAF): DRD2
Study 16803851 — Surrogate Endpoint (SUR): Blood pressure
Study 14529100 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6607245 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 29766633 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26694940 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 26694940 — Surrogate Endpoint (SUR): Blood pressure
Study 17490659 — Surrogate Endpoint (SUR): Bone mineral density
Study 17490659 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7989509 — Surrogate Endpoint (SUR): Sperm parameters
Study 391578 — Surrogate Endpoint (SUR): Serum uric acid
Study 25648347 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 3291895 — Surrogate Endpoint (SUR): Blood pressure
Study 26482148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26482148 — Surrogate Endpoint (SUR): Blood pressure
Study 24013186 — Predictive Biomarker (PRD): SLC38A3 mRNA
Genes: SLC38A3; G17; NAT1; SN1; SNAT3
Study 24013186 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 19597368 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16716211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16716211 — Surrogate Endpoint (SUR): Blood pressure
Study 3967455 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 31094229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31094229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31094229 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31094229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31094229 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31094229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23792641 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23792641 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 21521342 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 26435334 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 25218194 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25218194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9879342 — Safety Biomarker (SAF): Interleukin 1
Study 9879342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9879342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8602597 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31710095 — Safety Biomarker (SAF): Nicotinamide phosphoribosyltransferase
Genes: NAMPT; PBEF; PBEF1
Study 31710095 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 19320570 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11524357 — Surrogate Endpoint (SUR): Blood pressure
Study 25063373 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20861587 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 10430198 — Surrogate Endpoint (SUR): Blood pressure
Study 8699873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8699873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8699873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8699873 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 21690475 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21690475 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10861151 — Surrogate Endpoint (SUR): Blood pressure
Study 2859273 — Surrogate Endpoint (SUR): Blood pressure
Study 12626887 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12626887 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 30765198 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30765198 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 30765198 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 29193016 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27570447 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17919608 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 12544289 — Surrogate Endpoint (SUR): Urinary oxalate
Study 8855809 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8855809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31281046 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 23916631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23916631 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3530781 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3530781 — Surrogate Endpoint (SUR): Blood pressure
Study 3530781 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30837554 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 23598060 — Predictive Biomarker (PRD): CHRNA7 mRNA
Genes: CHRNA7; NACHRA7
Study 23598060 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 18637070 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18637070 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 12040471 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12040471 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31856691 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7769501 — Surrogate Endpoint (SUR): Blood pressure
Study 7769501 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30078106 — Surrogate Endpoint (SUR): Blood pressure
Study 15723745 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15723745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15723745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15723745 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 1984216 — Surrogate Endpoint (SUR): Blood pressure
Study 29614706 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27255954 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 12934466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3510278 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 3510278 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 26179124 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study 7848072 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26504148 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 22459542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8572653 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7027234 — Surrogate Endpoint (SUR): Blood pressure
Study 31015099 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27927588 — Surrogate Endpoint (SUR): Blood pressure
Study 11600543 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11600543 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 15644155 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15644155 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 15644155 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15644155 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 24755722 — Surrogate Endpoint (SUR): Blood pressure
Study 22264722 — Surrogate Endpoint (SUR): Blood pressure
Study 22264722 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19066176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16279899 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 26788875 — Safety Biomarker (SAF): Hyaluronic acid
Study 23167574 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 16641126 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 11004060 — Surrogate Endpoint (SUR): Blood pressure
Study 1317272 — Surrogate Endpoint (SUR): Blood pressure
Study 31793541 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8018108 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8018108 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2738182 — Surrogate Endpoint (SUR): Blood pressure
Study 1059709 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30552112 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30552112 — Predictive Biomarker (PRD): Hormone receptor
Study 28376288 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26547464 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21888861 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 21888861 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 16814414 — Surrogate Endpoint (SUR): Serum creatinine
Study 8482047 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24709491 — Surrogate Endpoint (SUR): Serum creatinine
Study 24709491 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22495138 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22495138 — Surrogate Endpoint (SUR): Blood pressure
Study 22495138 — Surrogate Endpoint (SUR): Serum creatinine
Study 18820825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7641897 — Surrogate Endpoint (SUR): Bone mineral density
Study 24206541 — Surrogate Endpoint (SUR): Blood pressure
Study 23680739 — Surrogate Endpoint (SUR): Blood pressure
Study 23680739 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23680739 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21510308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11367646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12633545 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 24941838 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 24941838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24941838 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17917696 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16025961 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22108393 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28662074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26388539 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 18848957 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29797910 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 24170099 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 7564352 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7564352 — Surrogate Endpoint (SUR): Blood pressure
Study 2300545 — Surrogate Endpoint (SUR): Blood pressure
Study 20827168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20827168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20827168 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 20827168 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20827168 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20827168 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20827168 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 2497720 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 336174 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 25051056 — Surrogate Endpoint (SUR): Serum uric acid
Study 25051056 — Surrogate Endpoint (SUR): Blood pressure
Study 25051056 — Surrogate Endpoint (SUR): Serum creatinine
Study 30278517 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 21518375 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 21518375 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19284399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19284399 — Surrogate Endpoint (SUR): Blood pressure
Study 8308518 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8308518 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 25343945 — Surrogate Endpoint (SUR): Blood pressure
Study 25343945 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24622318 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10896230 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 3566358 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29973195 — Surrogate Endpoint (SUR): Blood pressure
Study 22955689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27192132 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12684609 — Surrogate Endpoint (SUR): Blood pressure
Study 8831181 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8831181 — Surrogate Endpoint (SUR): Blood pressure
Study 1336463 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1336463 — Surrogate Endpoint (SUR): Blood pressure
Study 4016825 — Surrogate Endpoint (SUR): Blood pressure
Study 19880909 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8374246 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21440501 — Surrogate Endpoint (SUR): Blood pressure
Study 21440501 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16750458 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16750458 — Surrogate Endpoint (SUR): Blood pressure
Study 10880268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3080283 — Safety Biomarker (SAF): N-acetylneuraminic acid
Study 16360059 — Surrogate Endpoint (SUR): Blood pressure
Study 7941918 — Surrogate Endpoint (SUR): Blood pressure
Study 7941918 — Surrogate Endpoint (SUR): Serum potassium
Study 29145543 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22974314 — Predictive Biomarker (PRD): GNS mRNA
Genes: GNS
Study 18675097 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 18675097 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2008181 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10836660 — Surrogate Endpoint (SUR): Blood pressure
Study 29271052 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 12423985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 12423985 — Predictive Biomarker (PRD): REEP5 mRNA
Genes: REEP5; C5orf18; DP1; TB2
Study 12423985 — Predictive Biomarker (PRD): Microsatellite instability
Study 10421388 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 10421388 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 10421388 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 382914 — Surrogate Endpoint (SUR): Blood pressure
Study 18957972 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18957972 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 1435159 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12741629 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18544972 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 8233387 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 3689627 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25828327 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19361602 — Surrogate Endpoint (SUR): Serum creatinine
Study 19361602 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11585680 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10408812 — Surrogate Endpoint (SUR): Blood pressure
Study 31416763 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29880175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29880175 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26950683 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10500075 — Surrogate Endpoint (SUR): Bone mineral density
Study 31615569 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25926739 — Surrogate Endpoint (SUR): Blood pressure
Study 15318311 — Surrogate Endpoint (SUR): Serum creatinine
Study 20647477 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 20647477 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 10320251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10320251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29543133 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 29543133 — Predictive Biomarker (PRD): ESRRG mRNA
Genes: ESRRG; ERR3; ERRG2; KIAA0832; NR3B3
Study 15191772 — Surrogate Endpoint (SUR): Serum creatinine
Study 9647140 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24341820 — Monitoring Biomarker (MOI): Procalcitonin
Study 17978999 — Predictive Biomarker (PRD): ARRB2 mRNA
Genes: ARRB2; ARB2; ARR2
Study 17978999 — Predictive Biomarker (PRD): HINT1 mRNA
Genes: HINT1; HINT; PKCI1; PRKCNH1
Study 15156311 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8053616 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28426106 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21814211 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21814211 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9456097 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9456097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23530305 — Surrogate Endpoint (SUR): Blood pressure
Study 30715261 — Predictive Biomarker (PRD): PRELID2 mRNA
Genes: PRELID2
Study 30715261 — Predictive Biomarker (PRD): G3BP2 mRNA
Genes: G3BP2; KIAA0660
Study 30715261 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 29946007 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22534523 — Surrogate Endpoint (SUR): Blood pressure
Study 18562489 — Predictive Biomarker (PRD): PTPN11 mRNA
Genes: PTPN11; PTP2C; SHPTP2
Study 8738857 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 22111350 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22111350 — Surrogate Endpoint (SUR): Blood pressure
Study 19779705 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15273337 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16332657 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 16332657 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 16332657 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 2084279 — Surrogate Endpoint (SUR): Blood pressure
Study 6938019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 31366352 — Safety Biomarker (SAF): Reactive oxygen species
Study 27534738 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27534738 — Surrogate Endpoint (SUR): Blood pressure