TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17351370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2496213 — Surrogate Endpoint (SUR): Serum calcium
Study 2496213 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 19417877 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27550085 — Surrogate Endpoint (SUR): Blood pressure
Study 22802308 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19874198 — Surrogate Endpoint (SUR): Bone mineral density
Study 7747819 — Safety Biomarker (SAF): Interleukin 1
Study 23376799 — Monitoring Biomarker (MOI): HBV DNA
Study 21992121 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9370387 — Surrogate Endpoint (SUR): Blood pressure
Study 30923022 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 29277895 — Predictive Biomarker (PRD): ACKR3 mRNA
Genes: ACKR3; CMKOR1; CXCR7; GPR159; RDC1
Study 29277895 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29277895 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 29277895 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25403681 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 24857100 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24857100 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24857100 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17953788 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 11778280 — Predictive Biomarker (PRD): HLF mRNA
Genes: HLF
Study 30453477 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 12918548 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 1290331 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6721124 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 30421439 — Surrogate Endpoint (SUR): Bone mineral density
Study 21784372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21784372 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9226601 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 22321279 — Surrogate Endpoint (SUR): Serum sodium
Study 22321279 — Surrogate Endpoint (SUR): Blood pressure
Study 19950759 — Surrogate Endpoint (SUR): Bone mineral density
Study 17101637 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30558758 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 25880052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25880052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25880052 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11254817 — Surrogate Endpoint (SUR): Bone mineral density
Study 29441973 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29441973 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29441973 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29441973 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24726635 — Surrogate Endpoint (SUR): Blood pressure
Study 16388832 — Surrogate Endpoint (SUR): Blood pressure
Study 6381968 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 6381968 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 6381968 — Surrogate Endpoint (SUR): Serum calcium
Study 6609268 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15886721 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15886721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14989068 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 10834778 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26282062 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 20609215 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 1974394 — Surrogate Endpoint (SUR): Blood pressure
Study 10449028 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 10449028 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6818806 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31262379 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 9868121 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12036640 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 24560365 — Predictive Biomarker (PRD): MOXD1 mRNA
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 24560365 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 10589001 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1836339 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1836339 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1836339 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1836339 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25153538 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 17657599 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8067834 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3051878 — Surrogate Endpoint (SUR): Blood pressure
Study 28874797 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 14735556 — Surrogate Endpoint (SUR): Blood pressure
Study 23082142 — Predictive Biomarker (PRD): AMHR2 mRNA
Genes: AMHR2; AMHR; MISR2
Study 23082142 — Predictive Biomarker (PRD): VEGFC mRNA
Genes: VEGFC
Study 23082142 — Predictive Biomarker (PRD): SERPINE2 mRNA
Genes: SERPINE2; PI7; PN1
Study 14985991 — Surrogate Endpoint (SUR): Plasma ammonia
Study 24231014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25293882 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25293882 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25293882 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17388753 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29284500 — Safety Biomarker (SAF): Interleukin 1
Study 3120436 — Surrogate Endpoint (SUR): Blood pressure
Study 24042066 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 21034646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30590353 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 19468948 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18041889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11329526 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25833983 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25833983 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21502454 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9270085 — Surrogate Endpoint (SUR): Blood pressure
Study 9270085 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2904883 — Surrogate Endpoint (SUR): Blood pressure
Study 18360019 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18360019 — Surrogate Endpoint (SUR): Blood pressure
Study 18360019 — Surrogate Endpoint (SUR): Serum creatinine
Study 14689753 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8475946 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2427835 — Surrogate Endpoint (SUR): Blood pressure
Study 29793629 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 29793629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24574431 — Safety Biomarker (SAF): Hyaluronic acid
Study 21423028 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14719212 — Surrogate Endpoint (SUR): Bone mineral density
Study 8857480 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8857480 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29334322 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29334322 — Safety Biomarker (SAF): BDNF
Study 27806243 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21778035 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15766835 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 7783110 — Surrogate Endpoint (SUR): Blood pressure
Study 25816197 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25816197 — Surrogate Endpoint (SUR): Blood pressure
Study 30958829 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11027739 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26903147 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 24564888 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study 24564888 — Predictive Biomarker (PRD): WNT5B mRNA
Genes: WNT5B
Study 24564888 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 16447661 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10522600 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 6814568 — Surrogate Endpoint (SUR): Blood pressure
Study 29295825 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 20681817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20681817 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11050785 — Surrogate Endpoint (SUR): Blood pressure
Study 1536941 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 12233877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30575978 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 26425688 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 19567922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21149659 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 1740401 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25342704 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 11118468 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 9188997 — Surrogate Endpoint (SUR): Blood pressure
Study 24608960 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21351264 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 21351264 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 30509271 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26751068 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 21946199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16269526 — Surrogate Endpoint (SUR): Bone mineral density
Study 12673718 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 12673718 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9568325 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8173690 — Surrogate Endpoint (SUR): Blood pressure
Study 20586934 — Monitoring Biomarker (MOI): HBV DNA
Study 18380628 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9494881 — Surrogate Endpoint (SUR): Blood pressure
Study 29580746 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 26928845 — Surrogate Endpoint (SUR): Serum testosterone
Study 23118021 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 23118021 — Predictive Biomarker (PRD): PTGDS mRNA
Genes: PTGDS; PDS
Study 6125195 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24923533 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 16033354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22839709 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 20346242 — Surrogate Endpoint (SUR): Serum creatinine
Study 400734 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 27052787 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 27052787 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 26692375 — Surrogate Endpoint (SUR): Blood pressure
Study 16859993 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16859993 — Surrogate Endpoint (SUR): Serum potassium
Study 16053779 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7889634 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7889634 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2198135 — Surrogate Endpoint (SUR): Blood pressure
Study 23799908 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 22938690 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 22938690 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28834483 — Surrogate Endpoint (SUR): Blood pressure
Study 25183702 — Surrogate Endpoint (SUR): Blood pressure
Study 22922526 — Surrogate Endpoint (SUR): Blood pressure
Study 10985512 — Surrogate Endpoint (SUR): Blood pressure
Study 10985512 — Surrogate Endpoint (SUR): Forced vital capacity
Study 4001842 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 18062829 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 18062829 — Predictive Biomarker (PRD): GCLC mRNA
Genes: GCLC; GLCL; GLCLC
Study 18062829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 8186159 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 26409883 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 15555291 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 23949731 — Surrogate Endpoint (SUR): Blood pressure
Study 22460385 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20541381 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31242981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27206952 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27206952 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19514187 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 9561984 — Safety Biomarker (SAF): Hypoxanthine-guanine phosphoribosyltransferase
Genes: HPRT1; HPRT
Study 19669678 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18441450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18441450 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10823763 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1995051 — Surrogate Endpoint (SUR): Blood pressure
Study 6400414 — Surrogate Endpoint (SUR): Blood pressure
Study 30371293 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24838369 — Predictive Biomarker (PRD): AKR1C3 mRNA
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 24838369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A1 mRNA
Genes: SRD5A1
Study 16889639 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15953135 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28003538 — Surrogate Endpoint (SUR): Bone mineral density
Study 26030325 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20354035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20354035 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10706930 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10706930 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8931030 — Surrogate Endpoint (SUR): Bone mineral density
Study 1442974 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27955652 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 24176943 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12439223 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 30867034 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30867034 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30867034 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24139127 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24139127 — Surrogate Endpoint (SUR): Blood pressure
Study 19700776 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 17605774 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9427706 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9427706 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 346356 — Surrogate Endpoint (SUR): Blood pressure
Study 25702059 — Surrogate Endpoint (SUR): Blood pressure
Study 23600983 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 31970477 — Surrogate Endpoint (SUR): Bone mineral density
Study 23060624 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 23060624 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8682118 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24219336 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21837746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21837746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 21837746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19411388 — Surrogate Endpoint (SUR): Blood pressure
Study 2690788 — Surrogate Endpoint (SUR): Blood pressure
Study 17273661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11434591 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 30366741 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 24841833 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25052890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19940325 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19940325 — Surrogate Endpoint (SUR): Blood pressure
Study 12468570 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12468570 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12468570 — Surrogate Endpoint (SUR): Blood pressure
Study 2483124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 326261 — Surrogate Endpoint (SUR): Serum alkaline phosphatase and bilirubin
Study 24520783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10442280 — Surrogate Endpoint (SUR): Serum sodium
Study 319938 — Surrogate Endpoint (SUR): Blood pressure
Study 26854669 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17557339 — Surrogate Endpoint (SUR): Blood pressure
Study 15809950 — Surrogate Endpoint (SUR): Blood pressure
Study 11518845 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11518845 — Safety Biomarker (SAF): Reactive oxygen species
Study 2455154 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2455154 — Surrogate Endpoint (SUR): Blood pressure
Study 30197501 — Surrogate Endpoint (SUR): Blood pressure
Study 20800632 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29802649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29802649 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 29802649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24585701 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 19349549 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2530019 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2530019 — Surrogate Endpoint (SUR): Blood pressure
Study 31325336 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 30907130 — Surrogate Endpoint (SUR): Blood pressure
Study 16886585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15579798 — Surrogate Endpoint (SUR): Bone mineral density
Study 9821760 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 8123837 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 30649163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23177745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20009911 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 17702881 — Surrogate Endpoint (SUR): Bone mineral density
Study 15165935 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 26725101 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21544086 — Surrogate Endpoint (SUR): Blood pressure
Study 12514146 — Predictive Biomarker (PRD): HR mRNA
Genes: HR