TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26641099 — Surrogate Endpoint (SUR): Blood pressure
Study 23595161 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 23595161 — Surrogate Endpoint (SUR): Blood pressure
Study 16950175 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16950175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12161769 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12161769 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 10450540 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 7759275 — Surrogate Endpoint (SUR): Blood pressure
Study 31411516 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 9112351 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1547684 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 3157577 — Surrogate Endpoint (SUR): Blood pressure
Study 24560760 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15503293 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28431480 — Predictive Biomarker (PRD): HMBS mRNA
Genes: HMBS; PBGD; UPS
Study 22514211 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19460770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15577621 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15577621 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3133712 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 30335073 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 25387888 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 23157654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9923569 — Surrogate Endpoint (SUR): Blood pressure
Study 8067223 — Surrogate Endpoint (SUR): Blood pressure
Study 31216547 — Surrogate Endpoint (SUR): Blood pressure
Study 25925999 — Surrogate Endpoint (SUR): Blood pressure
Study 15770435 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 8389738 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8389738 — Surrogate Endpoint (SUR): Blood pressure
Study 17409909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8784310 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31364286 — Predictive Biomarker (PRD): COL4A3 mRNA
Genes: COL4A3
Study 31364286 — Predictive Biomarker (PRD): COL4A4 mRNA
Genes: COL4A4
Study 31364286 — Predictive Biomarker (PRD): COL4A5 mRNA
Genes: COL4A5
Study 31364286 — Predictive Biomarker (PRD): NPHS1 mRNA
Genes: NPHS1; NPHN
Study 31364286 — Predictive Biomarker (PRD): EYA1 mRNA
Genes: EYA1
Study 31364286 — Predictive Biomarker (PRD): CLCN5 mRNA
Genes: CLCN5; CLCK2
Study 31364286 — Predictive Biomarker (PRD): LAMC1 mRNA
Genes: LAMC1; LAMB2
Study 27085434 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22219414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20432816 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20432816 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17980248 — Surrogate Endpoint (SUR): Serum creatinine
Study 17980248 — Surrogate Endpoint (SUR): Blood pressure
Study 15063404 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16750985 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11081782 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11081782 — Surrogate Endpoint (SUR): Blood pressure
Study 30823944 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30823944 — Safety Biomarker (SAF): Th2 cell
Study 25852208 — Surrogate Endpoint (SUR): Blood pressure
Study 15189958 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15189958 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 2551397 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 31441419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31441419 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 31441419 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25175554 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 23908318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23908318 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 23908318 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 11551575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8330828 — Surrogate Endpoint (SUR): Blood pressure
Study 30250241 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 30250241 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 30250241 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 30250241 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 12944209 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12944209 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12944209 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27930408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21455087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8259746 — Surrogate Endpoint (SUR): Blood pressure
Study 25760277 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 23551956 — Predictive Biomarker (PRD): MAOB mRNA
Genes: MAOB
Study 10673512 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8862237 — Surrogate Endpoint (SUR): Blood pressure
Study 6394516 — Surrogate Endpoint (SUR): Blood pressure
Study 18502109 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18502109 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 6138009 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 25413313 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15179210 — Surrogate Endpoint (SUR): Blood pressure
Study 31226721 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 22460183 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3706373 — Surrogate Endpoint (SUR): Blood pressure
Study 15897362 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15897362 — Surrogate Endpoint (SUR): Blood pressure
Study 14570950 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27724992 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 23597332 — Surrogate Endpoint (SUR): Blood pressure
Study 16800987 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 28056202 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15540688 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11583866 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18445674 — Surrogate Endpoint (SUR): Serum calcium
Study 24891317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26083408 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 23816410 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19434235 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25810849 — Surrogate Endpoint (SUR): Blood pressure
Study 11454885 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11454885 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 11454885 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 7921311 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31608934 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24942170 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10389775 — Surrogate Endpoint (SUR): Blood pressure
Study 11791035 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7470518 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31654268 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 24413845 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 9667603 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8208596 — Surrogate Endpoint (SUR): Blood pressure
Study 23298603 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20839290 — Surrogate Endpoint (SUR): Bone mineral density
Study 26211411 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 7963709 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31772064 — Surrogate Endpoint (SUR): Blood pressure
Study 26654101 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 18419825 — Surrogate Endpoint (SUR): Blood pressure
Study 14984503 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 14984503 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 14984503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2868657 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16507515 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16507515 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8291370 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31096162 — Safety Biomarker (SAF): Reactive oxygen species
Study 21220480 — Predictive Biomarker (PRD): Hormone receptor
Study 21220480 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21220480 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28323947 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 20177421 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 17044952 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 14578921 — Surrogate Endpoint (SUR): Blood pressure
Study 21712736 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21712736 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21712736 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7814158 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22869943 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 31240388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26025630 — Surrogate Endpoint (SUR): Blood pressure
Study 22947355 — Safety Biomarker (SAF): CYP11B1 mRNA
Genes: CYP11B1; S11BH
Study 2274431 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28703124 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 28703124 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 28703124 — Surrogate Endpoint (SUR): Blood pressure
Study 20670096 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15327190 — Surrogate Endpoint (SUR): Blood pressure
Study 2975554 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31433717 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22382665 — Surrogate Endpoint (SUR): Blood pressure
Study 31074005 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 15225149 — Surrogate Endpoint (SUR): Blood pressure
Study 21739234 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 9178340 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 9178340 — Surrogate Endpoint (SUR): Blood pressure
Study 26959652 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11874387 — Surrogate Endpoint (SUR): Blood pressure
Study 6136936 — Surrogate Endpoint (SUR): Blood pressure
Study 31892489 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31892489 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23511299 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23511299 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 30170781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30170781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30170781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25809236 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 25809236 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21751435 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31486158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31486158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22082677 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22082677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 20538833 — Surrogate Endpoint (SUR): Serum uric acid
Study 20538833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12915697 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 22315948 — Surrogate Endpoint (SUR): Blood pressure
Study 7506675 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7506675 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2574766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2574766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26156625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26156625 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21971374 — Surrogate Endpoint (SUR): Bone mineral density
Study 9226735 — Safety Biomarker (SAF): DRD2
Study 29059139 — Safety Biomarker (SAF): Hyaluronic acid
Study 18327010 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11044230 — Surrogate Endpoint (SUR): Blood pressure
Study 11044230 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27779461 — Surrogate Endpoint (SUR): Blood pressure
Study 12398965 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12398965 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7752918 — Surrogate Endpoint (SUR): Blood pressure
Study 27292104 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 22300739 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22300739 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 19543205 — Safety Biomarker (SAF): Reactive oxygen species
Study 31838924 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 25898203 — Predictive Biomarker (PRD): GARS1 mRNA
Genes: GARS1; GARS
Study 19786221 — Surrogate Endpoint (SUR): Bacterial count
Study 9199118 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 9199118 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 9199118 — Surrogate Endpoint (SUR): Blood pressure
Study 1672698 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1672698 — Surrogate Endpoint (SUR): Blood pressure
Study 18981951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17244766 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12428688 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 23178794 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 23178794 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 23178794 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 9950098 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28716357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11006427 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 11006427 — Surrogate Endpoint (SUR): Bacterial count
Study 11006427 — Surrogate Endpoint (SUR): Serum antibody concentration
Study 9206240 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 6692650 — Surrogate Endpoint (SUR): Blood pressure
Study 22318394 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 14985677 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22735866 — Surrogate Endpoint (SUR): Blood pressure
Study 17653691 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 15774493 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10405985 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10405985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24290960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22658931 — Predictive Biomarker (PRD): SPSB1 mRNA
Genes: SPSB1; SSB1
Study 22658931 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 11988933 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 28219610 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23289969 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23289969 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 10954887 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20979731 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18832293 — Predictive Biomarker (PRD): AKR1C1 mRNA
Genes: AKR1C1; DDH; DDH1
Study 18832293 — Predictive Biomarker (PRD): AKR1C2 mRNA
Genes: AKR1C2; DDH2
Study 18832293 — Predictive Biomarker (PRD): AKR1C3 mRNA
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 12934402 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 6298047 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 22959886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22959886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22959886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22959886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17446340 — Surrogate Endpoint (SUR): Blood pressure
Study 17446340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17446340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9756554 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9756554 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9756554 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 26725391 — Predictive Biomarker (PRD): PLIN1 mRNA
Genes: PLIN1; PERI; PLIN
Study 26725391 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PLIN4 mRNA
Genes: PLIN4; KIAA1881
Study 8867395 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8867395 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24255061 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 24255061 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22894911 — Surrogate Endpoint (SUR): Blood pressure
Study 12842237 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2060564 — Surrogate Endpoint (SUR): Blood pressure
Study 2060564 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16091635 — Surrogate Endpoint (SUR): Blood pressure
Study 29535047 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 27548212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24724616 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 24724616 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 24724616 — Safety Biomarker (SAF): DRD2
Study 22012257 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 22012257 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 22012257 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22012257 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 22012257 — Predictive Biomarker (PRD): ALDH3A1 mRNA
Genes: ALDH3A1; ALDH3
Study 22012257 — Predictive Biomarker (PRD): GSTA1 mRNA
Genes: GSTA1
Study 19382614 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15464683 — Predictive Biomarker (PRD): TBC1D8 mRNA
Genes: TBC1D8; VRP
Study 9251066 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 9251066 — Surrogate Endpoint (SUR): Blood pressure
Study 9251066 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 8480959 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3816087 — Surrogate Endpoint (SUR): Blood pressure
Study 25710083 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 25063211 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 14671195 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19284125 — Surrogate Endpoint (SUR): Blood pressure