TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29228822 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23943825 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23943825 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 23943825 — Surrogate Endpoint (SUR): Bone mineral density
Study 19052855 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19052855 — Surrogate Endpoint (SUR): Blood pressure
Study 10826401 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10826401 — Surrogate Endpoint (SUR): Blood pressure
Study 10826401 — Surrogate Endpoint (SUR): Serum potassium
Study 6397541 — Surrogate Endpoint (SUR): Blood pressure
Study 25031274 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22414522 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 10671818 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 10671818 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6650766 — Surrogate Endpoint (SUR): Serum sodium
Study 26762988 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26762988 — Surrogate Endpoint (SUR): Bone mineral density
Study 17006376 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10789186 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30165479 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 25038486 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24620920 — Monitoring Biomarker (MOI): HBV DNA
Study 28659138 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 27800649 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27800649 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19531212 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11668308 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 7877519 — Surrogate Endpoint (SUR): Blood pressure
Study 27846824 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23460707 — Predictive Biomarker (PRD): GLI2 mRNA
Genes: GLI2; THP
Study 20529344 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 20529344 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 20529344 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18971890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7966600 — Monitoring Biomarker (MOI): HBV DNA
Study 29187694 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 29187694 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27638812 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16890481 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27287210 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2028627 — Surrogate Endpoint (SUR): Blood pressure
Study 28675660 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26393645 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10669372 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 8229139 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 8889352 — Surrogate Endpoint (SUR): Blood pressure
Study 16371185 — Surrogate Endpoint (SUR): Serum calcium
Study 8555805 — Surrogate Endpoint (SUR): Blood pressure
Study 26910781 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26910781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7526027 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 7526027 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7526027 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 7526027 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 19011227 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19011227 — Surrogate Endpoint (SUR): Blood pressure
Study 28542805 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17010541 — Surrogate Endpoint (SUR): Bone mineral density
Study 7828258 — Surrogate Endpoint (SUR): Blood pressure
Study 31883728 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 31883728 — Surrogate Endpoint (SUR): Blood pressure
Study 17357764 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20608874 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16467544 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11273139 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9359537 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29865227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29865227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24836866 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24836866 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15797313 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1453598 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1453598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27143684 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22703382 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 20006592 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 11237351 — Predictive Biomarker (PRD): MATN1 mRNA
Genes: MATN1; CMP; CRTM
Study 8297216 — Surrogate Endpoint (SUR): Blood pressure
Study 11198483 — Surrogate Endpoint (SUR): Blood pressure
Study 30530801 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 26367064 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 1534646 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17386350 — Surrogate Endpoint (SUR): Blood pressure
Study 16623036 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28923084 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 28923084 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10984013 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 9001327 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 8105943 — Surrogate Endpoint (SUR): Serum calcium
Study 8105943 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31504110 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24448010 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19236785 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 12492609 — Surrogate Endpoint (SUR): Blood pressure
Study 785608 — Surrogate Endpoint (SUR): Blood pressure
Study 26214684 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23687089 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 23687089 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 23687089 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 23687089 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 23687089 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 23687089 — Predictive Biomarker (PRD): CDKN2B mRNA
Genes: CDKN2B; MTS2
Study 23687089 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 23687089 — Predictive Biomarker (PRD): BCL11B mRNA
Genes: BCL11B; CTIP2; RIT1
Study 17370665 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 17370665 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15220300 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 2116057 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 28004188 — Surrogate Endpoint (SUR): Serum creatinine
Study 22018631 — Predictive Biomarker (PRD): Hormone receptor
Study 19886855 — Surrogate Endpoint (SUR): Blood pressure
Study 15378542 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30400586 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 30400586 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22301466 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 10051277 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 6966082 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27488051 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 11817529 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 11817529 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 20571015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17324600 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17324600 — Surrogate Endpoint (SUR): Blood pressure
Study 17324600 — Surrogate Endpoint (SUR): Serum sodium
Study 17324600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17324600 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11893367 — Surrogate Endpoint (SUR): Bone mineral density
Study 8495830 — Surrogate Endpoint (SUR): Serum creatinine
Study 8495830 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8495830 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 2468875 — Surrogate Endpoint (SUR): Blood pressure
Study 24305424 — Safety Biomarker (SAF): Hyaluronic acid
Study 21429720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21429720 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21429720 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21429720 — Surrogate Endpoint (SUR): Serum uric acid
Study 28541646 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 28254462 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 21547897 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14602435 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1434725 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24665980 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 22462425 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 22462425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23547849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23547849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10191213 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10191213 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7762255 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 7762255 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 28000034 — Surrogate Endpoint (SUR): Bone mineral density
Study 9517646 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 7922791 — Surrogate Endpoint (SUR): Bone mineral density
Study 1940775 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 18180889 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18180889 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 11486790 — Surrogate Endpoint (SUR): Bone mineral density
Study 8252746 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 3545477 — Surrogate Endpoint (SUR): Blood pressure
Study 3545477 — Surrogate Endpoint (SUR): Serum potassium
Study 20308250 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 20308250 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 20308250 — Safety Biomarker (SAF): Reactive oxygen species
Study 18400273 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15807179 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15807179 — Surrogate Endpoint (SUR): Bone mineral density
Study 24615745 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23073360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23073360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23073360 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15936187 — Surrogate Endpoint (SUR): Blood pressure
Study 8780818 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8780818 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 26556733 — Surrogate Endpoint (SUR): Bone mineral density
Study 17923601 — Surrogate Endpoint (SUR): Serum sodium
Study 8548332 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8548332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29179761 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 10588784 — Surrogate Endpoint (SUR): Blood pressure
Study 28640389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26974989 — Surrogate Endpoint (SUR): Blood pressure
Study 25283137 — Predictive Biomarker (PRD): GSTZ1 mRNA
Genes: GSTZ1; MAAI
Study 11165973 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7970086 — Surrogate Endpoint (SUR): Serum creatinine
Study 31702992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26007320 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26007320 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19934458 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study 12484510 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25268099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25268099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25268099 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 25268099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20022809 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 779561 — Surrogate Endpoint (SUR): Blood pressure
Study 28698169 — Surrogate Endpoint (SUR): Blood pressure
Study 28698169 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18427130 — Surrogate Endpoint (SUR): Blood pressure
Study 16540826 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16540826 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 6786412 — Surrogate Endpoint (SUR): Blood pressure
Study 28024270 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23535211 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 23535211 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 23535211 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 18842151 — Surrogate Endpoint (SUR): Bone mineral density
Study 8204811 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26512967 — Predictive Biomarker (PRD): ABCA3 mRNA
Genes: ABCA3; ABC3
Study 26512967 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 26512967 — Predictive Biomarker (PRD): ABCC3 mRNA
Genes: ABCC3; CMOAT2; MLP2; MRP3
Study 26512967 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 19933411 — Surrogate Endpoint (SUR): Serum uric acid
Study 19933411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 201006 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 17599881 — Surrogate Endpoint (SUR): Blood pressure
Study 2636671 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19295240 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19295240 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15208005 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 12043313 — Safety Biomarker (SAF): Hyaluronic acid
Study 31508796 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 15543222 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15543222 — Surrogate Endpoint (SUR): Blood pressure
Study 25239451 — Surrogate Endpoint (SUR): Bacterial count
Study 11811565 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3514193 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29064599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29064599 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16254730 — Surrogate Endpoint (SUR): Blood pressure
Study 9493662 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9493662 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 31793041 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 12859221 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 1309944 — Surrogate Endpoint (SUR): Blood pressure
Study 1309944 — Surrogate Endpoint (SUR): Bone mineral density
Study 1309944 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 1309944 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1309944 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24568487 — Predictive Biomarker (PRD): NDP mRNA
Genes: NDP; EVR2
Study 12195325 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 28492492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26110548 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23375006 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8382120 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 12383667 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12383667 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12840867 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12840867 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 12840867 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 8772970 — Surrogate Endpoint (SUR): Blood pressure
Study 29132930 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24660837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22681705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17720993 — Predictive Biomarker (PRD): UCN2 mRNA
Genes: UCN2; SRP; URP
Study 14514944 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8695107 — Surrogate Endpoint (SUR): Blood pressure
Study 1832500 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 26681392 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26681392 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25561817 — Predictive Biomarker (PRD): TTK mRNA
Genes: TTK; MPS1; MPS1L1
Study 25561817 — Monitoring Biomarker (MOI): HBV DNA
Study 25561817 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27806191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17460368 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2904826 — Surrogate Endpoint (SUR): Blood pressure
Study 25665612 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25665612 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25665612 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28109258 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 14757687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14757687 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3025306 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 12351269 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 29493100 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27607411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8859177 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 26821697 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17704023 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17704023 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16178985 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12045164 — Safety Biomarker (SAF): Interleukin 1
Study 12045164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2