TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30458732 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 30458732 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30458732 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30458732 — Predictive Biomarker (PRD): Hormone receptor
Study 26875070 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 8260854 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 30728488 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22287677 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 31157583 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15117729 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8004359 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 18194593 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 12888140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12888140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24374803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16685547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21222132 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 21222132 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 17606053 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 11513310 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9633801 — Surrogate Endpoint (SUR): Blood pressure
Study 8018000 — Surrogate Endpoint (SUR): Blood pressure
Study 26009832 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16575284 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11095423 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 11095423 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2934708 — Surrogate Endpoint (SUR): Serum creatinine
Study 16060412 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16060412 — Surrogate Endpoint (SUR): Blood pressure
Study 16060412 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12136446 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 6996986 — Surrogate Endpoint (SUR): Blood pressure
Study 16978370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9763553 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7679164 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28468607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26073387 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26073387 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26073387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22679695 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19041224 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19915217 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11736880 — Surrogate Endpoint (SUR): Blood pressure
Study 9253326 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 9253326 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31501165 — Surrogate Endpoint (SUR): Blood pressure
Study 27940956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18425621 — Predictive Biomarker (PRD): TCHH mRNA
Genes: TCHH; THH; THL; TRHY
Study 14511846 — Surrogate Endpoint (SUR): Blood pressure
Study 31124397 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 22152087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22152087 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24702733 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16182831 — Surrogate Endpoint (SUR): Blood pressure
Study 22739083 — Surrogate Endpoint (SUR): Blood pressure
Study 10327295 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 8904258 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 24174321 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 20937657 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 8590846 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17146025 — Surrogate Endpoint (SUR): Bone mineral density
Study 12750437 — Predictive Biomarker (PRD): SLC15A1 mRNA
Genes: SLC15A1; PEPT1
Study 12750437 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 12750437 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 8813775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22616062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22616062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20736206 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20736206 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 7486485 — Surrogate Endpoint (SUR): Blood pressure
Study 7486485 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31605197 — Surrogate Endpoint (SUR): Blood pressure
Study 27508295 — Surrogate Endpoint (SUR): Blood pressure
Study 25172025 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25172025 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 25172025 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 25172025 — Safety Biomarker (SAF): BDNF
Study 24136883 — Surrogate Endpoint (SUR): Pathological complete response
Study 18951992 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16082155 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10089262 — Surrogate Endpoint (SUR): Blood pressure
Study 21367927 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 11331253 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26432772 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study 26432772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 7989081 — Surrogate Endpoint (SUR): Blood pressure
Study 24821582 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 22532941 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23963895 — Surrogate Endpoint (SUR): Blood pressure
Study 19583932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31527020 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 19916101 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 20717126 — Surrogate Endpoint (SUR): Plasma ammonia
Study 9660243 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9660243 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27926769 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 27926769 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 27926769 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26030651 — Surrogate Endpoint (SUR): Blood pressure
Study 16686769 — Surrogate Endpoint (SUR): Serum creatinine
Study 25398374 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 25398374 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25398374 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 25398374 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 25398374 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 25398374 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 25398374 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 25398374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21710170 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12627188 — Surrogate Endpoint (SUR): Blood pressure
Study 30198779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30198779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30198779 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20890710 — Surrogate Endpoint (SUR): Blood pressure
Study 16813773 — Predictive Biomarker (PRD): GARS1 mRNA
Genes: GARS1; GARS
Study 16813773 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11515714 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 30787295 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30787295 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28106245 — Surrogate Endpoint (SUR): Blood pressure
Study 10347985 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30592390 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 30592390 — Safety Biomarker (SAF): Hyaluronic acid
Study 7697848 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 30279028 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 11422739 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11422739 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28844985 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 22859496 — Monitoring Biomarker (MOI): HBV DNA
Study 17823447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9051389 — Surrogate Endpoint (SUR): Blood pressure
Study 2451815 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 31933342 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15208504 — Surrogate Endpoint (SUR): Serum creatinine
Study 2782692 — Surrogate Endpoint (SUR): Blood pressure
Study 21324674 — Surrogate Endpoint (SUR): Bone mineral density
Study 28782603 — Surrogate Endpoint (SUR): Blood pressure
Study 15322504 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 15322504 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27416774 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 27416774 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 23543447 — Monitoring Biomarker (MOI): HBV DNA
Study 28795342 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28795342 — Surrogate Endpoint (SUR): Serum calcium
Study 12078940 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12078940 — Surrogate Endpoint (SUR): Blood pressure
Study 11008323 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8536820 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22521543 — Surrogate Endpoint (SUR): Bone mineral density
Study 9400906 — Surrogate Endpoint (SUR): Blood pressure
Study 27904000 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27904000 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25033743 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 25033743 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18279374 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 16030275 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1853859 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27089049 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27089049 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 23126348 — Surrogate Endpoint (SUR): Blood pressure
Study 24678906 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 9500624 — Surrogate Endpoint (SUR): Serum creatinine
Study 29932230 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 28641972 — Surrogate Endpoint (SUR): Bone mineral density
Study 26169592 — Predictive Biomarker (PRD): PPP1R13L mRNA
Genes: PPP1R13L; IASPP; NKIP1; PPP1R13BL; RAI
Study 23063567 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 20097683 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 20097683 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16725260 — Surrogate Endpoint (SUR): Blood pressure
Study 1468089 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1468089 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30249366 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 1851183 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 31518174 — Predictive Biomarker (PRD): Hormone receptor
Study 31518174 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28698350 — Surrogate Endpoint (SUR): Blood pressure
Study 28698350 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28698350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28698350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28698350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22616228 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 17473298 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23658161 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 20060517 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 9469128 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21467028 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21467028 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23255569 — Surrogate Endpoint (SUR): Blood pressure
Study 12598354 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15374185 — Predictive Biomarker (PRD): DEK mRNA
Genes: DEK
Study 30987662 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 14723561 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 7920748 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7920748 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12393605 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 31895286 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 30696670 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 23924261 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 20008230 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 20008230 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 15520364 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 9683002 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8062317 — Surrogate Endpoint (SUR): Blood pressure
Study 22194858 — Predictive Biomarker (PRD): ANKRD1 mRNA
Genes: ANKRD1; C193; CARP; HA1A2
Study 22194858 — Predictive Biomarker (PRD): CH25H mRNA
Genes: CH25H
Study 22194858 — Predictive Biomarker (PRD): CXCL2 mRNA
Genes: CXCL2; GRO2; GROB; MIP2A; SCYB2
Study 22194858 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 22194858 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22194858 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22194858 — Predictive Biomarker (PRD): NFIL3 mRNA
Genes: NFIL3; E4BP4; IL3BP1
Study 22194858 — Predictive Biomarker (PRD): SELE mRNA
Genes: SELE; ELAM1
Study 22194858 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 10718834 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9327193 — Surrogate Endpoint (SUR): Blood pressure
Study 6942649 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16789405 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25994905 — Surrogate Endpoint (SUR): Bone mineral density
Study 18188136 — Surrogate Endpoint (SUR): Blood pressure
Study 16564292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16564292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1595343 — Surrogate Endpoint (SUR): Blood pressure
Study 23841267 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23841267 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10585345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8915969 — Surrogate Endpoint (SUR): Blood pressure
Study 8915969 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20530499 — Surrogate Endpoint (SUR): Serum calcium
Study 8750154 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 8750154 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7854375 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28509727 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24129974 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18357434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3631561 — Surrogate Endpoint (SUR): Blood pressure
Study 30558556 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 26913407 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15812748 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3018566 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3018566 — Surrogate Endpoint (SUR): Blood pressure
Study 29984884 — Surrogate Endpoint (SUR): Blood pressure
Study 8031553 — Surrogate Endpoint (SUR): Blood pressure
Study 8031553 — Surrogate Endpoint (SUR): Serum sodium
Study 31383430 — Surrogate Endpoint (SUR): Blood pressure
Study 17243547 — Surrogate Endpoint (SUR): Bone mineral density
Study 12777909 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16330205 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21575967 — Surrogate Endpoint (SUR): Serum testosterone
Study 23038174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3537545 — Surrogate Endpoint (SUR): Serum creatinine
Study 30347780 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30347780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30347780 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30347780 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30347780 — Surrogate Endpoint (SUR): Blood pressure
Study 27084247 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25026897 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10703660 — Safety Biomarker (SAF): Interleukin 1
Study 10703660 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10703660 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1350192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24439983 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 10408405 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 6123089 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 22415479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19329013 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17597085 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24561971 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24561971 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29544534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29354971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25701866 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS