TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27428678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11131270 — Surrogate Endpoint (SUR): Blood pressure
Study 8696533 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8148228 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 28985270 — Surrogate Endpoint (SUR): Serum uric acid
Study 28985270 — Surrogate Endpoint (SUR): Blood pressure
Study 10335727 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8606849 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28862017 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27688102 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23213986 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23213986 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23213986 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17455405 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 17455405 — Surrogate Endpoint (SUR): Blood pressure
Study 2685688 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20576266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20576266 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20576266 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20347483 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31904693 — Surrogate Endpoint (SUR): Blood pressure
Study 20823898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1604414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15777683 — Predictive Biomarker (PRD): BMP4 mRNA
Genes: BMP4; BMP2B; DVR4
Study 10651262 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 10651262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23317096 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 18362499 — Surrogate Endpoint (SUR): Bone mineral density
Study 22011460 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22011460 — Surrogate Endpoint (SUR): Blood pressure
Study 12145664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28323627 — Surrogate Endpoint (SUR): Serum creatinine
Study 28323627 — Safety Biomarker (SAF): Interleukin 1
Study 28323627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23549122 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 22035998 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 22035998 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 22035998 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 27295865 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10051966 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10051966 — Surrogate Endpoint (SUR): Blood pressure
Study 23061628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23061628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23061628 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 23061628 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11759263 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 7828395 — Surrogate Endpoint (SUR): Serum potassium
Study 3338014 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2149806 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 23666250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23666250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23666250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21158922 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21158922 — Surrogate Endpoint (SUR): Serum potassium
Study 21158922 — Surrogate Endpoint (SUR): Serum creatinine
Study 18762944 — Surrogate Endpoint (SUR): Bone mineral density
Study 19948879 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15950634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11809166 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 2053568 — Surrogate Endpoint (SUR): Blood pressure
Study 24639242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24639242 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17270521 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 10354124 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 25891753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25891753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25891753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19885996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19885996 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 1775594 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 26511489 — Predictive Biomarker (PRD): HDAC6 mRNA
Genes: HDAC6; KIAA0901; JM21
Study 26511489 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 22876876 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 1438647 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 22042946 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26817916 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 26817916 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 21392832 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21392832 — Surrogate Endpoint (SUR): Blood pressure
Study 20178593 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20178593 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12501129 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11477814 — Surrogate Endpoint (SUR): Blood pressure
Study 28087049 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 22736121 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 22736121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12464749 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 22192331 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7502276 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1778354 — Surrogate Endpoint (SUR): Blood pressure
Study 28650331 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28650331 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 28650331 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 15910687 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30614881 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 11335691 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 15800308 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 28663062 — Surrogate Endpoint (SUR): Blood pressure
Study 17087311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8369231 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 28183816 — Predictive Biomarker (PRD): SLC2A2 mRNA
Genes: SLC2A2; GLUT2
Study 28183816 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 26156733 — Surrogate Endpoint (SUR): Blood pressure
Study 23369067 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 1384762 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22450889 — Surrogate Endpoint (SUR): Serum creatinine
Study 10565450 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10565450 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10565450 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27161546 — Surrogate Endpoint (SUR): Blood pressure
Study 15677559 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18042668 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 31864393 — Safety Biomarker (SAF): Urinary microalbumin
Study 27434221 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 27434221 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21382967 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 18827063 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 9893071 — Surrogate Endpoint (SUR): Bone mineral density
Study 367678 — Surrogate Endpoint (SUR): Blood pressure
Study 19002271 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10831026 — Surrogate Endpoint (SUR): Blood pressure
Study 30610155 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20040339 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12087006 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 7751430 — Surrogate Endpoint (SUR): Blood pressure
Study 29202767 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 26338699 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9013370 — Surrogate Endpoint (SUR): Blood pressure
Study 22465175 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9678793 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 9678793 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9678793 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19343018 — Surrogate Endpoint (SUR): Blood pressure
Study 26033416 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25528363 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 12053583 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 11995457 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11995457 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10431942 — Surrogate Endpoint (SUR): Blood pressure
Study 2124540 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 6628517 — Surrogate Endpoint (SUR): Blood pressure
Study 12398954 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7783314 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 23763989 — Predictive Biomarker (PRD): RNPEP mRNA
Genes: RNPEP; APB
Study 23763989 — Predictive Biomarker (PRD): DBNL mRNA
Genes: DBNL; CMAP; SH3P7; PP5423
Study 23763989 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 23361170 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21491486 — Surrogate Endpoint (SUR): Bone mineral density
Study 12623166 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12623166 — Surrogate Endpoint (SUR): Blood pressure
Study 30302936 — Surrogate Endpoint (SUR): Blood pressure
Study 15840110 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15840110 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 10333932 — Surrogate Endpoint (SUR): Blood pressure
Study 31870450 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25059460 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 23187648 — Surrogate Endpoint (SUR): Blood pressure
Study 8748432 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8748432 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8173699 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8173699 — Surrogate Endpoint (SUR): Blood pressure
Study 12466341 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12466341 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12466341 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10603716 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 7794078 — Surrogate Endpoint (SUR): Blood pressure
Study 2041036 — Surrogate Endpoint (SUR): Blood pressure
Study 31109190 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 26107684 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 26107684 — Surrogate Endpoint (SUR): Bone mineral density
Study 24565122 — Surrogate Endpoint (SUR): Blood pressure
Study 15478524 — Surrogate Endpoint (SUR): Blood pressure
Study 11566628 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 2851506 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29645341 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20089518 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 14639800 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31698825 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31698825 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27301235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27301235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12216602 — Surrogate Endpoint (SUR): Blood pressure
Study 31067189 — Surrogate Endpoint (SUR): Blood pressure
Study 23134470 — Monitoring Biomarker (MOI): HBV DNA
Study 12815774 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12815774 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 12815774 — Surrogate Endpoint (SUR): Blood pressure
Study 19105461 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 17000363 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9268234 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27337519 — Surrogate Endpoint (SUR): Serum testosterone
Study 27337519 — Surrogate Endpoint (SUR): Sperm parameters
Study 23681085 — Surrogate Endpoint (SUR): Bone mineral density
Study 18775652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28039399 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 28039399 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 12826040 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 9807847 — Surrogate Endpoint (SUR): Blood pressure
Study 7659241 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31035474 — Surrogate Endpoint (SUR): Blood pressure
Study 23863812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19628740 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19628740 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 12807578 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 31074652 — Safety Biomarker (SAF): Reactive oxygen species
Study 18548148 — Surrogate Endpoint (SUR): Blood pressure
Study 11761770 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22151909 — Surrogate Endpoint (SUR): Blood pressure
Study 322672 — Surrogate Endpoint (SUR): Blood pressure
Study 24934401 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 20089074 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 12135946 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 12135946 — Surrogate Endpoint (SUR): Blood pressure
Study 7777104 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7777104 — Safety Biomarker (SAF): Reactive oxygen species
Study 111943 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26746221 — Surrogate Endpoint (SUR): Blood pressure
Study 26746221 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29688503 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22188731 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17687758 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 17687758 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14651722 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 14651722 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27009278 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 27009278 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 24293371 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24293371 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11684077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8017467 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8017467 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8017467 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2597808 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 4397654 — Surrogate Endpoint (SUR): Blood pressure
Study 21931376 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 21931376 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17525586 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11393342 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11393342 — Surrogate Endpoint (SUR): Blood pressure
Study 9581728 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23864130 — Surrogate Endpoint (SUR): Blood pressure
Study 8640072 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2996156 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28770596 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24803495 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 24803495 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 21999189 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14712348 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 10730110 — Surrogate Endpoint (SUR): Blood pressure
Study 1901332 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17048428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8689841 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 22244743 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17929306 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 31039826 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 9421749 — Predictive Biomarker (PRD): OSR1 mRNA
Genes: OSR1; ODD
Study 27986077 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15635110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15635110 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30901428 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29133942 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18270842 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12879082 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28763434 — Surrogate Endpoint (SUR): Serum sodium
Study 12771706 — Surrogate Endpoint (SUR): Bone mineral density
Study 9331129 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8164452 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30405294 — Surrogate Endpoint (SUR): Blood pressure
Study 18377099 — Surrogate Endpoint (SUR): Serum calcium
Study 10226868 — Surrogate Endpoint (SUR): Blood pressure
Study 27845956 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 27845956 — Surrogate Endpoint (SUR): Blood pressure
Study 21352389 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 18045825 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12847992 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12847992 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11429120 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11429120 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26299230 — Surrogate Endpoint (SUR): Blood pressure
Study 27159854 — Surrogate Endpoint (SUR): Blood pressure
Study 12858227 — Predictive Biomarker (PRD): MNDA mRNA
Genes: MNDA
Study 24903323 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27307536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15647412 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 8619442 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8619442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20646413 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 20646413 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 15764620 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11783181 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 2350832 — Predictive Biomarker (PRD): TG mRNA
Genes: TG