TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22851600 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17575559 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12669741 — Surrogate Endpoint (SUR): Serum calcium
Study 28079501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28079501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28079501 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28079501 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 22989372 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 19889690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19889690 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18505181 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 29129443 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26852501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16785738 — Surrogate Endpoint (SUR): Serum creatinine
Study 19004201 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 31294749 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 25822236 — Surrogate Endpoint (SUR): Blood pressure
Study 23434449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23434449 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 26412178 — Predictive Biomarker (PRD): AHSP mRNA
Genes: AHSP; EDRF; ERAF
Study 19117033 — Surrogate Endpoint (SUR): Serum calcium
Study 21150602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16389160 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27982269 — Surrogate Endpoint (SUR): Blood pressure
Study 26302034 — Safety Biomarker (SAF): Hyaluronic acid
Study 30882595 — Surrogate Endpoint (SUR): Blood pressure
Study 22465578 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18039351 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16200601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14612278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14612278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7008475 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8088970 — Surrogate Endpoint (SUR): Serum creatinine
Study 3406600 — Surrogate Endpoint (SUR): Blood pressure
Study 24996197 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17645384 — Surrogate Endpoint (SUR): Blood pressure
Study 31915170 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 30849947 — Surrogate Endpoint (SUR): Blood pressure
Study 23143672 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7683480 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 2961688 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 2961688 — Surrogate Endpoint (SUR): Blood pressure
Study 29119530 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 9440719 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 9440719 — Predictive Biomarker (PRD): NRSN1 mRNA
Genes: NRSN1; VMP
Study 9440719 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 7912567 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 7912567 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7912567 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 31833974 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9607059 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 19828574 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 15639688 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15639688 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15639688 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15639688 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7701456 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25633893 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25633893 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 25633893 — Safety Biomarker (SAF): Reactive oxygen species
Study 21688658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21688658 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21688658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26066346 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3538487 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8762375 — Surrogate Endpoint (SUR): Blood pressure
Study 8762375 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23721506 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23721506 — Surrogate Endpoint (SUR): Blood pressure
Study 25458637 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3330528 — Surrogate Endpoint (SUR): Blood pressure
Study 24295403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24295403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16814647 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16814647 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11006795 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11006795 — Surrogate Endpoint (SUR): Bone mineral density
Study 29172851 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26705884 — Surrogate Endpoint (SUR): Bone mineral density
Study 24481962 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 22892585 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22892585 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 17389702 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 10396539 — Surrogate Endpoint (SUR): Blood pressure
Study 26990559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26990559 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22052102 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17115155 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24749263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24749263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6350878 — Surrogate Endpoint (SUR): Serum creatinine
Study 27167669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15073684 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29665619 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 29665619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17130515 — Predictive Biomarker (PRD): Hormone receptor
Study 11246179 — Surrogate Endpoint (SUR): Blood pressure
Study 9589225 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 20669013 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20669013 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15691622 — Surrogate Endpoint (SUR): Blood pressure
Study 7398099 — Surrogate Endpoint (SUR): Serum creatinine
Study 25890359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17699383 — Surrogate Endpoint (SUR): Serum creatinine
Study 1305819 — Surrogate Endpoint (SUR): Blood pressure
Study 23701209 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23701209 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 23701209 — Surrogate Endpoint (SUR): Blood pressure
Study 19138360 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 16960448 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 16960448 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11190581 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9332997 — Surrogate Endpoint (SUR): Blood pressure
Study 18598003 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 18598003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18598003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18598003 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15860254 — Safety Biomarker (SAF): Reactive oxygen species
Study 29499976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26094080 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 17322490 — Surrogate Endpoint (SUR): Bone mineral density
Study 11576153 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11576153 — Surrogate Endpoint (SUR): Blood pressure
Study 28444660 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28444660 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28444660 — Safety Biomarker (SAF): BDNF
Study 28444660 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23216762 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17044763 — Surrogate Endpoint (SUR): Blood pressure
Study 6146425 — Surrogate Endpoint (SUR): Blood pressure
Study 14693303 — Surrogate Endpoint (SUR): Blood pressure
Study 30232865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30232865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30232865 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30232865 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 30232865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26626336 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 11581563 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30573748 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30573748 — Pharmacodynamic Biomarker (PDY): Cytokine ML-1
Genes: IL17F
Study 25210017 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 19050386 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17515448 — Predictive Biomarker (PRD): NE
Study 17515448 — Surrogate Endpoint (SUR): Blood pressure
Study 16316699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16316699 — Surrogate Endpoint (SUR): Blood pressure
Study 12746013 — Surrogate Endpoint (SUR): Blood pressure
Study 7703597 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3316118 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22134392 — Surrogate Endpoint (SUR): Blood pressure
Study 9579811 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 29622600 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29622600 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24095299 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 21165807 — Surrogate Endpoint (SUR): Bone mineral density
Study 6731323 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18040529 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16120075 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10192649 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9296412 — Surrogate Endpoint (SUR): Blood pressure
Study 2871783 — Surrogate Endpoint (SUR): Blood pressure
Study 15905191 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 21742012 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21742012 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 16261517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12072677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12072677 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10190722 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2224694 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27393080 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 25976296 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27761943 — Predictive Biomarker (PRD): LMX1A mRNA
Genes: LMX1A
Study 19144985 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 3189422 — Surrogate Endpoint (SUR): Serum creatinine
Study 3189422 — Surrogate Endpoint (SUR): Blood pressure
Study 31327203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27875537 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 20369718 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 20369718 — Safety Biomarker (SAF): Reactive oxygen species
Study 17395047 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17395047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17395047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17395047 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 17395047 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 375958 — Surrogate Endpoint (SUR): Blood pressure
Study 11155471 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11155471 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8636779 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1583243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1583243 — Safety Biomarker (SAF): Interleukin 1
Study 31000783 — Surrogate Endpoint (SUR): Blood pressure
Study 30053018 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 15805860 — Predictive Biomarker (PRD): SERPINB3 mRNA
Genes: SERPINB3; SCCA; SCCA1
Study 10756363 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 8882473 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 19016711 — Predictive Biomarker (PRD): CYP26A1 mRNA
Genes: CYP26A1; CYP26; P450RAI1
Study 19016711 — Predictive Biomarker (PRD): CRABP2 mRNA
Genes: CRABP2
Study 19016711 — Predictive Biomarker (PRD): KRT2 mRNA
Genes: KRT2; KRT2A; KRT2E
Study 19016711 — Predictive Biomarker (PRD): KRT4 mRNA
Genes: KRT4; CYK4
Study 19016711 — Predictive Biomarker (PRD): CYP26B1 mRNA
Genes: CYP26B1; CYP26A2; P450RAI2
Study 19016711 — Predictive Biomarker (PRD): CYP26C1 mRNA
Genes: CYP26C1
Study 19016711 — Predictive Biomarker (PRD): CYP2S1 mRNA
Genes: CYP2S1; UNQ891/PRO1906
Study 19016711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31221553 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25884717 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16770243 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 15585778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11745270 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23842829 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21816223 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 25501623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25501623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21508140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19080072 — Surrogate Endpoint (SUR): Blood pressure
Study 29658441 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27525994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24490264 — Surrogate Endpoint (SUR): Serum creatinine
Study 14642411 — Surrogate Endpoint (SUR): Blood pressure
Study 14642411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9372379 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9372379 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27303100 — Surrogate Endpoint (SUR): Serum uric acid
Study 29961686 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 8908230 — Surrogate Endpoint (SUR): Blood pressure
Study 6195235 — Surrogate Endpoint (SUR): Bacterial count
Study 20012022 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 18593294 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8003862 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2591109 — Surrogate Endpoint (SUR): Serum calcium
Study 2591109 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17014062 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 17014062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9211466 — Surrogate Endpoint (SUR): Blood pressure
Study 24093950 — Surrogate Endpoint (SUR): Serum creatinine
Study 24093950 — Surrogate Endpoint (SUR): Serum potassium
Study 19636689 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19636689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19636689 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9754450 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 25171898 — Surrogate Endpoint (SUR): Blood pressure
Study 25171898 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25171898 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14640237 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14640237 — Surrogate Endpoint (SUR): Blood pressure
Study 21049213 — Surrogate Endpoint (SUR): Blood pressure
Study 15671108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10359886 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 10359886 — Predictive Biomarker (PRD): C-C motif chemokine 7
Genes: CCL7; MCP3; SCYA6; SCYA7
Study 31786980 — Surrogate Endpoint (SUR): Blood pressure
Study 30876658 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19049753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14624406 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 14624406 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26703220 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26703220 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26703220 — Surrogate Endpoint (SUR): Serum testosterone
Study 15802405 — Surrogate Endpoint (SUR): Bone mineral density
Study 12161495 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12161495 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8540613 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 30261474 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 27041692 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34