TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18324566 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15944869 — Surrogate Endpoint (SUR): Blood pressure
Study 8872291 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8872291 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 8872291 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 8872291 — Surrogate Endpoint (SUR): Blood pressure
Study 27030325 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 27030325 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 25351025 — Surrogate Endpoint (SUR): Blood pressure
Study 22583627 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 19915976 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28846633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26244985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22891564 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 22891564 — Safety Biomarker (SAF): Reactive oxygen species
Study 22891564 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30265563 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27927679 — Predictive Biomarker (PRD): ALPI mRNA
Genes: ALPI
Study 11114960 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11114960 — Surrogate Endpoint (SUR): Blood pressure
Study 8264873 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 17897465 — Surrogate Endpoint (SUR): Blood pressure
Study 9793844 — Surrogate Endpoint (SUR): Blood pressure
Study 2558817 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23257975 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23257975 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11704081 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 9606848 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29606517 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20802351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19054833 — Surrogate Endpoint (SUR): Blood pressure
Study 10348802 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 10348802 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 1777376 — Surrogate Endpoint (SUR): Blood pressure
Study 6519740 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6519740 — Surrogate Endpoint (SUR): Blood pressure
Study 27566633 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20399240 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31022932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31022932 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22206712 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 22206712 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23532145 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 8261880 — Predictive Biomarker (PRD): MAOB mRNA
Genes: MAOB
Study 24201230 — Surrogate Endpoint (SUR): Blood pressure
Study 21613553 — Surrogate Endpoint (SUR): Blood pressure
Study 19549290 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 19549290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19549290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11231700 — Surrogate Endpoint (SUR): Blood pressure
Study 7912123 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9094875 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9094875 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22627991 — Surrogate Endpoint (SUR): Blood pressure
Study 10574621 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2935737 — Surrogate Endpoint (SUR): Blood pressure
Study 29893769 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 29893769 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 29893769 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 29893769 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 29893769 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 29893769 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29893769 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29893769 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCNE2 mRNA
Genes: CCNE2
Study 29893769 — Predictive Biomarker (PRD): Hormone receptor
Study 9892860 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 24859203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21390056 — Surrogate Endpoint (SUR): Blood pressure
Study 30939905 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 10898125 — Surrogate Endpoint (SUR): Serum creatinine
Study 10898125 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9360001 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9360001 — Surrogate Endpoint (SUR): Blood pressure
Study 2879292 — Surrogate Endpoint (SUR): Blood pressure
Study 29856470 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 10382902 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29126178 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29126178 — Surrogate Endpoint (SUR): Blood pressure
Study 15572589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15572589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7623005 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2821080 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2821080 — Surrogate Endpoint (SUR): Blood pressure
Study 26178748 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 16259942 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20127563 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 20127563 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 20127563 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 20127563 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 20127563 — Monitoring Biomarker (MOI): Angiopoietin 1 receptor
Genes: TEK; TIE2; VMCM; VMCM1
Study 9735677 — Safety Biomarker (SAF): MTHFR
Study 31319637 — Surrogate Endpoint (SUR): Blood pressure
Study 19736179 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28851099 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28851099 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28851099 — Safety Biomarker (SAF): Interleukin 1
Study 22441004 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20202819 — Surrogate Endpoint (SUR): Blood pressure
Study 17699341 — Surrogate Endpoint (SUR): Serum sodium
Study 8923574 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 10450013 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31269677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-143
Genes: MIR143
Study 31269677 — Monitoring Biomarker (MOI): miR-195-5p
Genes: MIR195
Study 31269677 — Safety Biomarker (SAF): miR-30a
Genes: MIR30A
Study 19361362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8874677 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1412754 — Surrogate Endpoint (SUR): Serum creatinine
Study 3927371 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 26037276 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 24246616 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24246616 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 25146059 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 23742676 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 23742676 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20058619 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20058619 — Surrogate Endpoint (SUR): Blood pressure
Study 20058619 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20058619 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10917406 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22990943 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 22990943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22990943 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22990943 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): VGF mRNA
Genes: VGF
Study 22990943 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 22990943 — Safety Biomarker (SAF): BDNF
Study 16184460 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16184460 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16184460 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27733180 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18191416 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 7449302 — Surrogate Endpoint (SUR): Blood pressure
Study 15129412 — Predictive Biomarker (PRD): SFPQ mRNA
Genes: SFPQ; PSF
Study 1203854 — Predictive Biomarker (PRD): POMP mRNA
Genes: POMP; C13orf12; UMP1; HSPC014; HSPC036; PNAS-110
Study 26160625 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26160625 — Surrogate Endpoint (SUR): Blood pressure
Study 30871628 — Predictive Biomarker (PRD): KIR3DL1 mRNA
Genes: KIR3DL1; CD158E; NKAT3; NKB1
Study 25648736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25648736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25648736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22974280 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 6939007 — Surrogate Endpoint (SUR): Blood pressure
Study 16447644 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16447644 — Surrogate Endpoint (SUR): Blood pressure
Study 9824407 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 8109551 — Surrogate Endpoint (SUR): Blood pressure
Study 8109551 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8267066 — Surrogate Endpoint (SUR): Blood pressure
Study 23468980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21527583 — Predictive Biomarker (PRD): TGFBR1 mRNA
Genes: TGFBR1; ALK5; SKR4
Study 21527583 — Predictive Biomarker (PRD): ALK
Genes: CD246; ALK1
Study 21527583 — Predictive Biomarker (PRD): LTBP1 mRNA
Genes: LTBP1
Study 21527583 — Predictive Biomarker (PRD): LTBP4 mRNA
Genes: LTBP4
Study 21527583 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 21527583 — Predictive Biomarker (PRD): TGFB2 mRNA
Genes: TGFB2
Study 21527583 — Predictive Biomarker (PRD): TGFBR2 mRNA
Genes: TGFBR2
Study 21527583 — Predictive Biomarker (PRD): SMAD1 mRNA
Genes: SMAD1; BSP1; MADH1; MADR1
Study 21527583 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 21527583 — Predictive Biomarker (PRD): SMAD3 mRNA
Genes: SMAD3; MADH3
Study 21527583 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study 24850844 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20883232 — Surrogate Endpoint (SUR): Blood pressure
Study 9440387 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 6340806 — Surrogate Endpoint (SUR): Blood pressure
Study 16815260 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 24625508 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2238575 — Surrogate Endpoint (SUR): Serum creatinine
Study 30249211 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 30249211 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 15926017 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 10340911 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 7569455 — Surrogate Endpoint (SUR): Blood pressure
Study 22791300 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22791300 — Surrogate Endpoint (SUR): Blood pressure
Study 20106932 — Predictive Biomarker (PRD): NOCT mRNA
Genes: NOCT; CCR4; CCRN4L; NOC
Study 29302858 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24584818 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20507841 — Safety Biomarker (SAF): Hyaluronic acid
Study 24127924 — Monitoring Biomarker (MOI): HBV DNA
Study 18081359 — Safety Biomarker (SAF): Hyaluronic acid
Study 30813779 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30948622 — Predictive Biomarker (PRD): DIAPH2 mRNA
Genes: DIAPH2; DIA
Study 18848470 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 17128343 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 9207470 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8256988 — Surrogate Endpoint (SUR): Bone mineral density
Study 31914620 — Predictive Biomarker (PRD): TFEB mRNA
Genes: TFEB; BHLHE35
Study 31914620 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 27988144 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 15080791 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24423341 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 24423341 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 24423341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24423341 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 24423341 — Predictive Biomarker (PRD): TIMP3 mRNA
Genes: TIMP3
Study 27592206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27592206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24593836 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24593836 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8622612 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25694037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25694037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25694037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6129380 — Surrogate Endpoint (SUR): Blood pressure
Study 26707418 — Predictive Biomarker (PRD): ALPI mRNA
Genes: ALPI
Study 22422931 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29164421 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29164421 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20159131 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18627323 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11821720 — Surrogate Endpoint (SUR): Blood pressure
Study 7130553 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 26390517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 24959775 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 19750404 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12632413 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10535720 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8767243 — Surrogate Endpoint (SUR): Blood pressure
Study 6625217 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 31657166 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 31657166 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26848137 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 11463600 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9875685 — Surrogate Endpoint (SUR): Serum creatinine
Study 2607521 — Surrogate Endpoint (SUR): Blood pressure
Study 30855722 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30855722 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26531275 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26531275 — Safety Biomarker (SAF): BDNF
Study 26687836 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 26687836 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 26687836 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10574598 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 8665034 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 27809891 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 29481636 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 9622166 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 7619649 — Surrogate Endpoint (SUR): Blood pressure
Study 2569309 — Surrogate Endpoint (SUR): Blood pressure
Study 26590673 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26590673 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 15378665 — Surrogate Endpoint (SUR): Blood pressure
Study 26988367 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26988367 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22890714 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 22890714 — Safety Biomarker (SAF): Reactive oxygen species
Study 20135144 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18056004 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18056004 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 16260969 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 7572582 — Surrogate Endpoint (SUR): Blood pressure
Study 630793 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 630793 — Surrogate Endpoint (SUR): Blood pressure
Study 27130927 — Surrogate Endpoint (SUR): Blood pressure
Study 15093884 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 11422755 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25319120 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 25319120 — Surrogate Endpoint (SUR): Blood pressure
Study 8338056 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 27032107 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20591499 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 18714150 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1418029 — Safety Biomarker (SAF): Interleukin 1
Study 31798713 — Surrogate Endpoint (SUR): Bone mineral density
Study 25015912 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30478814 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 21415069 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12406891 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12406891 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18389675 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18389675 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15804248 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 10233426 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30829316 — Predictive Biomarker (PRD): ZEB1 mRNA
Genes: ZEB1; AREB6; TCF8
Study 30548426 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30548426 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 30548426 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 30548426 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 21813573 — Surrogate Endpoint (SUR): Blood pressure
Study 31634532 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8615323 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8615323 — Surrogate Endpoint (SUR): Blood pressure
Study 30768429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16969378 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12121721 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25226336 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 25226336 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20368213 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 20368213 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28330458 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 25576682 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10710119 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20044530 — Surrogate Endpoint (SUR): Blood pressure
Study 23272667 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16433897 — Surrogate Endpoint (SUR): Blood pressure
Study 31963773 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 29242937 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR