TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10868643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25538197 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17713346 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 17713346 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1404502 — Surrogate Endpoint (SUR): Blood pressure
Study 21095267 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12892806 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7851597 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 28487444 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23819631 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23819631 — Surrogate Endpoint (SUR): Blood pressure
Study 21078948 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19506159 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 9660150 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31409158 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31409158 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25961616 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16397284 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16397284 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9279217 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29548345 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19846183 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 30717779 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 30717779 — Surrogate Endpoint (SUR): Blood pressure
Study 20194302 — Surrogate Endpoint (SUR): Blood pressure
Study 17536128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17536128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17536128 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7752655 — Surrogate Endpoint (SUR): Blood pressure
Study 1963691 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 24861389 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31935109 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28822516 — Surrogate Endpoint (SUR): Blood pressure
Study 22027728 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25719610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25719610 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19208697 — Surrogate Endpoint (SUR): Blood pressure
Study 27513367 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23356247 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23348954 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23348954 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 19004195 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 9483407 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9483407 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 31705874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14598948 — Surrogate Endpoint (SUR): Serum sodium
Study 14598948 — Surrogate Endpoint (SUR): Blood pressure
Study 1574972 — Surrogate Endpoint (SUR): Blood pressure
Study 2967315 — Predictive Biomarker (PRD): CEACAM6 mRNA
Genes: CEACAM6; NCA
Study 16978071 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8298198 — Surrogate Endpoint (SUR): Bone mineral density
Study 8298198 — Surrogate Endpoint (SUR): Serum calcium
Study 8298198 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 25215557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25215557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22179810 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22179810 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18022088 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 6364370 — Surrogate Endpoint (SUR): Serum calcium
Study 6364370 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30057015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14514570 — Surrogate Endpoint (SUR): Blood pressure
Study 1394057 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 15680854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8282352 — Surrogate Endpoint (SUR): Blood pressure
Study 3177083 — Surrogate Endpoint (SUR): Blood pressure
Study 24094693 — Predictive Biomarker (PRD): KCNQ2 mRNA
Genes: KCNQ2
Study 10861652 — Monitoring Biomarker (MOI): HBV DNA
Study 9144683 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27802427 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 2495053 — Surrogate Endpoint (SUR): Blood pressure
Study 21162644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31145699 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19665415 — Surrogate Endpoint (SUR): Blood pressure
Study 14964492 — Safety Biomarker (SAF): Interleukin 1
Study 9797181 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9797181 — Surrogate Endpoint (SUR): Blood pressure
Study 22618923 — Surrogate Endpoint (SUR): Blood pressure
Study 8749695 — Surrogate Endpoint (SUR): Serum creatinine
Study 8749695 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 27116645 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27116645 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 27116645 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 10757081 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10757081 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 10757081 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 27038714 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27038714 — Surrogate Endpoint (SUR): Serum creatinine
Study 25318892 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 25318892 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 16083533 — Safety Biomarker (SAF): Hyaluronic acid
Study 12177656 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30445611 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25307976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25307976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25307976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25307976 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19010943 — Surrogate Endpoint (SUR): Blood pressure
Study 14764753 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 14764753 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 14764753 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 14764753 — Surrogate Endpoint (SUR): Bone mineral density
Study 14764753 — Surrogate Endpoint (SUR): Serum testosterone
Study 11321143 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 8989254 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22243943 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 22243943 — Surrogate Endpoint (SUR): Blood pressure
Study 19710156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23186975 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17875305 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 17875305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11094868 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11094868 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11094868 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 11094868 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11094868 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 25621158 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25621158 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11588406 — Surrogate Endpoint (SUR): Blood pressure
Study 7639807 — Safety Biomarker (SAF): Interleukin 1
Study 7639807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31809326 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 24939678 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 15925816 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15925816 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 21320366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21320366 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19944363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19944363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19944363 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31669047 — Surrogate Endpoint (SUR): Blood pressure
Study 6173204 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31329216 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 17463301 — Safety Biomarker (SAF): IL-6 and IL-10
Study 11055475 — Surrogate Endpoint (SUR): Blood pressure
Study 3723262 — Surrogate Endpoint (SUR): Serum sodium
Study 24458074 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24458074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22632452 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 12716484 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17607437 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 17607437 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 16141440 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25613468 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18710606 — Surrogate Endpoint (SUR): Blood pressure
Study 2695566 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28417914 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 21884148 — Surrogate Endpoint (SUR): Blood pressure
Study 9135873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2544117 — Surrogate Endpoint (SUR): Blood pressure
Study 19458028 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22184370 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 16006832 — Surrogate Endpoint (SUR): Blood pressure
Study 8553302 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 11706341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15890355 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2701039 — Surrogate Endpoint (SUR): Blood pressure
Study 30113523 — Safety Biomarker (SAF): Cytochrome c
Study 30113523 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16585287 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 28515079 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 21624416 — Predictive Biomarker (PRD): TLR5 mRNA
Genes: TLR5; TIL3
Study 21624416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12618330 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 12618330 — Predictive Biomarker (PRD): XRCC3 mRNA
Genes: XRCC3
Study 9596418 — Surrogate Endpoint (SUR): Blood pressure
Study 8172092 — Surrogate Endpoint (SUR): Blood pressure
Study 16369892 — Surrogate Endpoint (SUR): Bone mineral density
Study 6805621 — Surrogate Endpoint (SUR): Blood pressure
Study 26839066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26839066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26839066 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21779817 — Surrogate Endpoint (SUR): Bone mineral density
Study 15688191 — Surrogate Endpoint (SUR): Bone mineral density
Study 11888741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2120987 — Surrogate Endpoint (SUR): Blood pressure
Study 24668638 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14693962 — Surrogate Endpoint (SUR): Blood pressure
Study 27049269 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27049269 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 27049269 — Surrogate Endpoint (SUR): Blood pressure
Study 15531620 — Surrogate Endpoint (SUR): Blood pressure
Study 10360848 — Surrogate Endpoint (SUR): Blood pressure
Study 23042976 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23042976 — Predictive Biomarker (PRD): OPN1SW mRNA
Genes: OPN1SW; BCP
Study 23042976 — Monitoring Biomarker (MOI): HBV DNA
Study 21554881 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 14767408 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2119558 — Predictive Biomarker (PRD): PDPN mRNA
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 23194445 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 16709314 — Surrogate Endpoint (SUR): Bone mineral density
Study 11259889 — Surrogate Endpoint (SUR): Blood pressure
Study 25783889 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24002145 — Safety Biomarker (SAF): Hyaluronic acid
Study 10813713 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1449302 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2866492 — Surrogate Endpoint (SUR): Blood pressure
Study 29857012 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 9459335 — Safety Biomarker (SAF): MTHFR
Study 1090416 — Surrogate Endpoint (SUR): Blood pressure
Study 19376306 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 2467091 — Surrogate Endpoint (SUR): Blood pressure
Study 27195073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19549433 — Predictive Biomarker (PRD): TP53INP1 mRNA
Genes: TP53INP1; P53DINP1; SIP
Study 11879237 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 22056151 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22056151 — Surrogate Endpoint (SUR): Serum creatinine
Study 14693305 — Surrogate Endpoint (SUR): Blood pressure
Study 25690268 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25690268 — Surrogate Endpoint (SUR): Blood pressure
Study 20518948 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 20518948 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20518948 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20518948 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12397697 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12397697 — Surrogate Endpoint (SUR): Blood pressure
Study 26101239 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26101239 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26101239 — Predictive Biomarker (PRD): Hormone receptor
Study 19390338 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19390338 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3391736 — Surrogate Endpoint (SUR): Blood pressure
Study 31294771 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31294771 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19065446 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11468204 — Surrogate Endpoint (SUR): Blood pressure
Study 9736892 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 8184873 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21519580 — Surrogate Endpoint (SUR): Probing pocket depth
Study 27107097 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 14633079 — Surrogate Endpoint (SUR): Blood pressure
Study 17340064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17340064 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7857100 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 19451553 — Surrogate Endpoint (SUR): Blood pressure
Study 16815141 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30425466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30425466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30425466 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19628371 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24536060 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9142797 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29516595 — Surrogate Endpoint (SUR): Blood pressure
Study 24156746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 24156746 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24156746 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16552819 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 16552819 — Monitoring Biomarker (MOI): HBV DNA
Study 12666702 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 8775577 — Predictive Biomarker (PRD): CEACAM6 mRNA
Genes: CEACAM6; NCA
Study 23774272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23774272 — Surrogate Endpoint (SUR): Blood pressure
Study 19425222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19425222 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19425222 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17689635 — Surrogate Endpoint (SUR): Blood pressure
Study 2155747 — Surrogate Endpoint (SUR): Blood pressure
Study 6966069 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 25484023 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22658255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22658255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11700394 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 11700394 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11700394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22901887 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2657055 — Surrogate Endpoint (SUR): Blood pressure
Study 30057745 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19933962 — Surrogate Endpoint (SUR): Blood pressure
Study 31166260 — Safety Biomarker (SAF): Hyaluronic acid
Study 26683057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 23827130 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19183113 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9737644 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7536025 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31076561 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31076561 — Surrogate Endpoint (SUR): Pathological complete response