TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12462290 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 12462290 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9156883 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9156883 — Surrogate Endpoint (SUR): Blood pressure
Study 24907435 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24907435 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22294470 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 22294470 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 9527740 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 19056600 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 15657470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7962322 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16652321 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12791811 — Predictive Biomarker (PRD): NOTCH3 mRNA
Genes: NOTCH3
Study 18045712 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18045712 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18045712 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18045712 — Surrogate Endpoint (SUR): Blood pressure
Study 2673437 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2931024 — Surrogate Endpoint (SUR): Blood pressure
Study 18503891 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 18503891 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 18503891 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 30654925 — Surrogate Endpoint (SUR): Blood pressure
Study 9409295 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9409295 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 9409295 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9409295 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9409295 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8287641 — Surrogate Endpoint (SUR): Blood pressure
Study 31287236 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31287236 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29503060 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 28383434 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28383434 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28383434 — Surrogate Endpoint (SUR): Blood pressure
Study 17894033 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 17894033 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 15646240 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 11740389 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11740389 — Surrogate Endpoint (SUR): Blood pressure
Study 30808949 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30808949 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 23190017 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 16527796 — Predictive Biomarker (PRD): CTSC mRNA
Genes: CTSC; CPPI
Study 12743003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15694946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15694946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9000657 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21092506 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 28325070 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28325070 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21736003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20137477 — Surrogate Endpoint (SUR): Bone mineral density
Study 823586 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 823586 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 26408873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26408873 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19426396 — Monitoring Biomarker (MOI): HBV DNA
Study 16434264 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 16434264 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15296810 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 31957953 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 31957953 — Predictive Biomarker (PRD): HPGDS mRNA
Genes: HPGDS; GSTS; PGDS; PTGDS2
Study 28274234 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 3139019 — Surrogate Endpoint (SUR): Bacterial count
Study 25850462 — Surrogate Endpoint (SUR): Blood pressure
Study 11171825 — Surrogate Endpoint (SUR): Blood pressure
Study 28895981 — Surrogate Endpoint (SUR): Blood pressure
Study 17497438 — Surrogate Endpoint (SUR): Serum creatinine
Study 14767720 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 31467115 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 12839661 — Surrogate Endpoint (SUR): Blood pressure
Study 12839661 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9374151 — Predictive Biomarker (PRD): TICAM2 mRNA
Genes: TICAM2; TIRAP3; TIRP; TRAM
Study 27025241 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 27025241 — Surrogate Endpoint (SUR): Blood pressure
Study 17217715 — Predictive Biomarker (PRD): CHD2 mRNA
Genes: CHD2
Study 17217715 — Predictive Biomarker (PRD): CHD3 mRNA
Genes: CHD3
Study 1583434 — Surrogate Endpoint (SUR): Blood pressure
Study 29480324 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 29480324 — Surrogate Endpoint (SUR): Blood pressure
Study 20969457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20969457 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 20969457 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20969457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11348882 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11348882 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 8392282 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8392282 — Surrogate Endpoint (SUR): Blood pressure
Study 20832103 — Predictive Biomarker (PRD): Hormone receptor
Study 19062727 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8554224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 6129951 — Surrogate Endpoint (SUR): Blood pressure
Study 30439785 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30439785 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28549319 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 27083334 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11349825 — Surrogate Endpoint (SUR): Blood pressure
Study 23276469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23276469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23276469 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14985966 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9438269 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 16940452 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16940452 — Surrogate Endpoint (SUR): Bone mineral density
Study 21295363 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 12100223 — Surrogate Endpoint (SUR): Blood pressure
Study 15477790 — Surrogate Endpoint (SUR): Blood pressure
Study 26489704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24964689 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 24964689 — Surrogate Endpoint (SUR): Blood pressure
Study 12195170 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30496493 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30496493 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21998121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8938674 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30690930 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25632744 — Surrogate Endpoint (SUR): Sperm parameters
Study 17221296 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12201354 — Surrogate Endpoint (SUR): Blood pressure
Study 9989963 — Surrogate Endpoint (SUR): Blood pressure
Study 2156343 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 2156343 — Surrogate Endpoint (SUR): Blood pressure
Study 7030636 — Surrogate Endpoint (SUR): Blood pressure
Study 2844641 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31743131 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26193861 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26193861 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12627316 — Surrogate Endpoint (SUR): Blood pressure
Study 11114637 — Surrogate Endpoint (SUR): Serum calcium
Study 26923987 — Predictive Biomarker (PRD): BMP2 mRNA
Genes: BMP2; BMP2A
Study 26923987 — Predictive Biomarker (PRD): BMP7 mRNA
Genes: BMP7; OP1
Study 25529979 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 25529979 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26615369 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25295770 — Surrogate Endpoint (SUR): Blood pressure
Study 11584376 — Monitoring Biomarker (MOI): HBV DNA
Study 3279350 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 29426379 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 24112810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18029109 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18029109 — Surrogate Endpoint (SUR): Serum creatinine
Study 10592457 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15753541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29843467 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11450476 — Surrogate Endpoint (SUR): Blood pressure
Study 31710844 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31106548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31106548 — Surrogate Endpoint (SUR): Serum uric acid
Study 31106548 — Surrogate Endpoint (SUR): Serum creatinine
Study 31106548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21161263 — Surrogate Endpoint (SUR): Blood pressure
Study 20031019 — Safety Biomarker (SAF): Hyaluronic acid
Study 3396574 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30305115 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30305115 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30305115 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30305115 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 30305115 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 30305115 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30305115 — Predictive Biomarker (PRD): LAMA2 mRNA
Genes: LAMA2; LAMM
Study 30305115 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 30305115 — Predictive Biomarker (PRD): MAP3K1 mRNA
Genes: MAP3K1; MAPKKK1; MEKK; MEKK1
Study 28973220 — Surrogate Endpoint (SUR): Blood pressure
Study 23427068 — Surrogate Endpoint (SUR): Bone mineral density
Study 17106197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27656713 — Surrogate Endpoint (SUR): Serum creatinine
Study 21675061 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 14767999 — Surrogate Endpoint (SUR): Serum sodium
Study 11416710 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25675385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17944658 — Surrogate Endpoint (SUR): Blood pressure
Study 15887898 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6388253 — Surrogate Endpoint (SUR): Blood pressure
Study 29324864 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 29324864 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29324864 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24186565 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 2681675 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31419272 — Surrogate Endpoint (SUR): Blood pressure
Study 12675873 — Surrogate Endpoint (SUR): Blood pressure
Study 8812622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25335327 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16252735 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8954418 — Predictive Biomarker (PRD): KY mRNA
Genes: KY
Study 26783095 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 26783095 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19376789 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 9747866 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9747866 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25614597 — Surrogate Endpoint (SUR): Blood pressure
Study 24024320 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 24024320 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 9081682 — Surrogate Endpoint (SUR): Blood pressure
Study 20606533 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12142558 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12142558 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 9657628 — Surrogate Endpoint (SUR): Blood pressure
Study 7644244 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 7644244 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 2507323 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 2507323 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26654907 — Surrogate Endpoint (SUR): Blood pressure
Study 8815273 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19193781 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 11598595 — Surrogate Endpoint (SUR): Bone mineral density
Study 25440329 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25440329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21921413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21921413 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21921413 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21921413 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9101306 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9101306 — Surrogate Endpoint (SUR): Blood pressure
Study 23363676 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7921519 — Surrogate Endpoint (SUR): Blood pressure
Study 3560070 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 3560070 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30709725 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24298765 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 12953031 — Surrogate Endpoint (SUR): Blood pressure
Study 10651673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10651673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12231566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12231566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12231566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2084236 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25873189 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 20143449 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20143449 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9250827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25650964 — Surrogate Endpoint (SUR): Blood pressure
Study 25650964 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24338119 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20817859 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 20817859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17451421 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 17451421 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7920000 — Surrogate Endpoint (SUR): Bone mineral density
Study 31269419 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 28742643 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 1414966 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26862857 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 12873920 — Surrogate Endpoint (SUR): Blood pressure
Study 10723498 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6890361 — Surrogate Endpoint (SUR): Blood pressure
Study 21736853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16443502 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 8017308 — Surrogate Endpoint (SUR): Blood pressure
Study 29131887 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10786962 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10786962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10786962 — Safety Biomarker (SAF): Interleukin 1
Study 4036270 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25872501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17192504 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 26463698 — Surrogate Endpoint (SUR): Blood pressure
Study 23822690 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11208851 — Surrogate Endpoint (SUR): Serum calcium
Study 29472356 — Predictive Biomarker (PRD): AKT3 mRNA
Genes: AKT3; PKBG
Study 29472356 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 29472356 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 29472356 — Predictive Biomarker (PRD): CD79B mRNA
Genes: CD79B; B29; IGB
Study 29472356 — Predictive Biomarker (PRD): PIK3CD mRNA
Genes: PIK3CD
Study 29472356 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 29472356 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 28327934 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 23701382 — Surrogate Endpoint (SUR): Blood pressure
Study 16485576 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10647074 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10647074 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2202547 — Surrogate Endpoint (SUR): Blood pressure
Study 6783979 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 25408262 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 25408262 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25408262 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23886915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16691030 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11778974 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 7934970 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29084372 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 20724597 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8800496 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6400113 — Surrogate Endpoint (SUR): Blood pressure
Study 15764762 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15764762 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 15764762 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10100058 — Surrogate Endpoint (SUR): Blood pressure