TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1696663 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1696663 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 1696663 — Surrogate Endpoint (SUR): Blood pressure
Study 23734617 — Surrogate Endpoint (SUR): Blood pressure
Study 21894807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16776752 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 11426092 — Surrogate Endpoint (SUR): Blood pressure
Study 10925339 — Surrogate Endpoint (SUR): Blood pressure
Study 6613138 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 21822678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2476604 — Surrogate Endpoint (SUR): Blood pressure
Study 29961888 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 29961888 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 29961888 — Surrogate Endpoint (SUR): Serum creatinine
Study 24816760 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24099796 — Predictive Biomarker (PRD): BBC3 mRNA
Genes: BBC3; PUMA
Study 24099796 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study 24099796 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 10950401 — Surrogate Endpoint (SUR): Blood pressure
Study 3537783 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22388001 — Surrogate Endpoint (SUR): Blood pressure
Study 11820861 — Predictive Biomarker (PRD): ALAD mRNA
Genes: ALAD
Study 31222759 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 31222759 — Predictive Biomarker (PRD): ALDH7A1 mRNA
Genes: ALDH7A1; ATQ1
Study 7516450 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14969070 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31062389 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 11597664 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11597664 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3328992 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23143621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9952147 — Surrogate Endpoint (SUR): Blood pressure
Study 8649928 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 28133708 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 21816087 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 19622756 — Surrogate Endpoint (SUR): Bone mineral density
Study 17317827 — Predictive Biomarker (PRD): TIMP3 mRNA
Genes: TIMP3
Study 17317827 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 17317827 — Predictive Biomarker (PRD): DAPK1 mRNA
Genes: DAPK1; DAPK
Study 17317827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): RASSF1A
Genes: RASSF1; NORE2A; REH3P21; RDA32; 123F2
Study 11435053 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9512323 — Surrogate Endpoint (SUR): Blood pressure
Study 8037411 — Surrogate Endpoint (SUR): Blood pressure
Study 31958336 — Surrogate Endpoint (SUR): Serum uric acid
Study 30477915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 9049584 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8349330 — Surrogate Endpoint (SUR): Blood pressure
Study 30554581 — Predictive Biomarker (PRD): SOX9 mRNA
Genes: SOX9
Study 30554581 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 30554581 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30554581 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30554581 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16115360 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16115360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7009908 — Surrogate Endpoint (SUR): Blood pressure
Study 3629186 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3629186 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 26198758 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 26198758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21156931 — Predictive Biomarker (PRD): CACNB2 mRNA
Genes: CACNB2; CACNLB2; MYSB
Study 16814412 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10519502 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31174055 — Surrogate Endpoint (SUR): Blood pressure
Study 31174055 — Surrogate Endpoint (SUR): Serum potassium
Study 22432725 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22432725 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3159346 — Predictive Biomarker (PRD): IFT122 mRNA
Genes: IFT122; SPG; WDR10; WDR140
Study 9013366 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26238672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17464552 — Surrogate Endpoint (SUR): Blood pressure
Study 11673814 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16507186 — Surrogate Endpoint (SUR): Blood pressure
Study 29572676 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 29572676 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 29572676 — Predictive Biomarker (PRD): DEFB4A mRNA
Genes: DEFB4A; DEFB102; DEFB2; DEFB4; DEFB4B
Study 29572676 — Predictive Biomarker (PRD): RSAD2 mRNA
Genes: RSAD2; CIG5
Study 29572676 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 29572676 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24059443 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 31551154 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31551154 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26134837 — Surrogate Endpoint (SUR): Blood pressure
Study 23786760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16835670 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16835670 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21587283 — Surrogate Endpoint (SUR): Blood pressure
Study 18423697 — Surrogate Endpoint (SUR): Bone mineral density
Study 10711705 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1376845 — Surrogate Endpoint (SUR): Blood pressure
Study 3888386 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 21329022 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21329022 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 17342992 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17342992 — Surrogate Endpoint (SUR): Serum creatinine
Study 17941026 — Surrogate Endpoint (SUR): Serum creatinine
Study 28625234 — Monitoring Biomarker (MOI): Procalcitonin
Study 16467101 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 16467101 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16467101 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 820622 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 25993590 — Surrogate Endpoint (SUR): Blood pressure
Study 23666746 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21863638 — Surrogate Endpoint (SUR): Serum creatinine
Study 17326152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 17326152 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 30218227 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 27139726 — Surrogate Endpoint (SUR): Blood pressure
Study 24622121 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12566834 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7828353 — Surrogate Endpoint (SUR): Urine free cortisol
Study 23168172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18374542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17768157 — Surrogate Endpoint (SUR): Serum creatinine
Study 12701260 — Surrogate Endpoint (SUR): Blood pressure
Study 26450146 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20093075 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 15613431 — Surrogate Endpoint (SUR): Blood pressure
Study 10074017 — Surrogate Endpoint (SUR): Blood pressure
Study 17924016 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11518851 — Surrogate Endpoint (SUR): Blood pressure
Study 9778268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9778268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9778268 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11602814 — Surrogate Endpoint (SUR): Blood pressure
Study 335572 — Predictive Biomarker (PRD): TMPRSS13 mRNA
Genes: TMPRSS13; MSP; TMPRSS11
Study 25538270 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17873301 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 7908624 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2892388 — Surrogate Endpoint (SUR): Blood pressure
Study 17876336 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17876336 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 28862513 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12009719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28438283 — Surrogate Endpoint (SUR): Blood pressure
Study 23212720 — Surrogate Endpoint (SUR): Blood pressure
Study 19454737 — Surrogate Endpoint (SUR): Blood pressure
Study 19454737 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3121836 — Surrogate Endpoint (SUR): Serum calcium
Study 25391865 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 23868011 — Predictive Biomarker (PRD): Hormone receptor
Study 16015270 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8453956 — Surrogate Endpoint (SUR): Blood pressure
Study 29228315 — Surrogate Endpoint (SUR): Pathological complete response
Study 29228315 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29228315 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 27128532 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 27128532 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 22623230 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20736987 — Surrogate Endpoint (SUR): Urinary oxalate
Study 26720308 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17299059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15214257 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 11225566 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 2571460 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 29458056 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 29458056 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 22875102 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 22875102 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22875102 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 28369670 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 20301883 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27287699 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 27287699 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18382839 — Surrogate Endpoint (SUR): Blood pressure
Study 14727988 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14727988 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 14727988 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24848522 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 27026675 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25185361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25185361 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 25185361 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25185361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21116604 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 9695723 — Surrogate Endpoint (SUR): Blood pressure
Study 31996953 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31996953 — Predictive Biomarker (PRD): Hormone receptor
Study 31996953 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28964890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22674612 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19023279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19023279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19023279 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19023279 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17562951 — Surrogate Endpoint (SUR): Serum creatinine
Study 11447379 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11447379 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 11447379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 11447379 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11447379 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10410574 — Surrogate Endpoint (SUR): Blood pressure
Study 8064166 — Surrogate Endpoint (SUR): Blood pressure
Study 8064166 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6119724 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 15157690 — Surrogate Endpoint (SUR): Blood pressure
Study 7805371 — Surrogate Endpoint (SUR): Blood pressure
Study 3280000 — Surrogate Endpoint (SUR): Serum creatinine
Study 28555959 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 10751074 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 20736151 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15693914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15693914 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12227708 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12227708 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27933512 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 27933512 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 27933512 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 27933512 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8210250 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 22216522 — Surrogate Endpoint (SUR): Blood pressure
Study 20137710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14714579 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29061547 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 24858506 — Surrogate Endpoint (SUR): Blood pressure
Study 22578980 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22578980 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31115845 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26636418 — Surrogate Endpoint (SUR): Serum testosterone
Study 10599182 — Surrogate Endpoint (SUR): Blood pressure
Study 7564036 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7564036 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 31782786 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 22926533 — Safety Biomarker (SAF): Reactive oxygen species
Study 20234119 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 20234119 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 2191586 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2191586 — Surrogate Endpoint (SUR): Blood pressure
Study 2191586 — Surrogate Endpoint (SUR): Serum potassium
Study 6775518 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22421017 — Safety Biomarker (SAF): Prognostic nutrition index
Study 20499117 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 3816081 — Surrogate Endpoint (SUR): Blood pressure
Study 2162258 — Surrogate Endpoint (SUR): Blood pressure
Study 23236208 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 20029377 — Surrogate Endpoint (SUR): Blood pressure
Study 20029377 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20029377 — Surrogate Endpoint (SUR): Serum uric acid
Study 20029377 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16155766 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12211225 — Surrogate Endpoint (SUR): Serum testosterone
Study 1354618 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1354618 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1354618 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31839169 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22651373 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 22651373 — Surrogate Endpoint (SUR): Bone mineral density
Study 18538469 — Surrogate Endpoint (SUR): Serum testosterone
Study 15854217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15854217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15854217 — Safety Biomarker (SAF): Interleukin 1
Study 15854217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10616949 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 6844366 — Surrogate Endpoint (SUR): Blood pressure
Study 18198195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11093698 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 9351876 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 31414957 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 28131837 — Safety Biomarker (SAF): Reactive oxygen species
Study 17311944 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 14967379 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14967379 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9476035 — Surrogate Endpoint (SUR): Blood pressure
Study 7946164 — Surrogate Endpoint (SUR): Blood pressure
Study 16624551 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16624551 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11078174 — Surrogate Endpoint (SUR): Blood pressure
Study 1400058 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20449689 — Predictive Biomarker (PRD): MZB1 mRNA
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 31606734 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30993323 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27783363 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 27783363 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 12837218 — Monitoring Biomarker (MOI): HBV DNA
Study 26586327 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26586327 — Surrogate Endpoint (SUR): Blood pressure
Study 16644288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16644288 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 12699019 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12699019 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10192233 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10192233 — Surrogate Endpoint (SUR): Blood pressure
Study 10192233 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein