TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25685360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25685360 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25686166 — Surrogate Endpoint (SUR): Blood pressure
Study 25687533 — Surrogate Endpoint (SUR): Bone mineral density
Study 25687566 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 25692692 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25694653 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 25696001 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25696001 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25698370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25699246 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 25700755 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25700774 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25700774 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 25700777 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25700777 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25701004 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25706232 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25710659 — Surrogate Endpoint (SUR): Blood pressure
Study 25710773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25710773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25710773 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25710812 — Surrogate Endpoint (SUR): Blood pressure
Study 25711328 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25712310 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25713293 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25713436 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25714519 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25715403 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25716544 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25720673 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25722272 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 25727652 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 25728526 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 25728732 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 25730509 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25730509 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25731869 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 25732635 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 25732635 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 25732635 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 25733005 — Predictive Biomarker (PRD): NEDD8 mRNA
Genes: NEDD8
Study 25734008 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25734008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25734163 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25736912 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 25739911 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25739926 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 25739926 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25740829 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 25740829 — Monitoring Biomarker (MOI): Complement C4
Study 25742200 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 25743200 — Surrogate Endpoint (SUR): Bone mineral density
Study 25744334 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 25744334 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 25746631 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 25748606 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25748864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25753361 — Predictive Biomarker (PRD): CDCA7L mRNA
Genes: CDCA7L; HR1; JPO2; R1
Study 25753656 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25753965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25753965 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25753965 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 25755291 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 25756303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25756303 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25756303 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25756398 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25756398 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25756398 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 25756398 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25756398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25758058 — Surrogate Endpoint (SUR): Blood pressure
Study 25758611 — Predictive Biomarker (PRD): ARSA mRNA
Genes: ARSA
Study 25758746 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 25758746 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 25758746 — Predictive Biomarker (PRD): EPHA2 mRNA
Genes: EPHA2; ECK
Study 25761057 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 25761189 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25761894 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25761894 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 25761894 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25761894 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 25761894 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 25762180 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 25762343 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 25762343 — Safety Biomarker (SAF): Hyaluronic acid
Study 25762355 — Surrogate Endpoint (SUR): Blood pressure
Study 25763783 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25763783 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25763783 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 25763789 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 25763789 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 25766256 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25766640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25766640 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25766898 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study 25768439 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25768671 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25768671 — Surrogate Endpoint (SUR): Serum sodium
Study 25769620 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 25770144 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25770144 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study 25770144 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25770676 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25772756 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25773989 — Predictive Biomarker (PRD): ATXN1 mRNA
Genes: ATXN1; ATX1; SCA1
Study 25773989 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 25773989 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 25777344 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25777345 — Surrogate Endpoint (SUR): Serum creatinine
Study 25778529 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25778850 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25780349 — Surrogate Endpoint (SUR): Serum creatinine
Study 25780518 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25781361 — Surrogate Endpoint (SUR): Blood pressure
Study 25781361 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25782122 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 25783622 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25783622 — Surrogate Endpoint (SUR): Blood pressure
Study 25785226 — Surrogate Endpoint (SUR): Bone mineral density
Study 25785995 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25785995 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25785995 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 25785995 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 25785995 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25786252 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 25786252 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 25786252 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25787057 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 25787923 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25787923 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25789614 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 25789989 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 25792386 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25792386 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25793152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25793933 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25793960 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25795432 — Surrogate Endpoint (SUR): Blood pressure
Study 25795917 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 25801567 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 25801567 — Predictive Biomarker (PRD): ABCC4 mRNA
Genes: ABCC4; MOATB; MRP4
Study 25801567 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 25801692 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 25801692 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25801692 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25801692 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 25801710 — Predictive Biomarker (PRD): IGF2R mRNA
Genes: IGF2R; MPRI
Study 25802238 — Predictive Biomarker (PRD): PRCC mRNA
Genes: PRCC; TPRC
Study 25802729 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25802932 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25803093 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 25803093 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25803226 — Surrogate Endpoint (SUR): Blood pressure
Study 25804569 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25804941 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 25804941 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25805361 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 25806231 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25806231 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 25806231 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 25806231 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 25806231 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25806231 — Predictive Biomarker (PRD): UIMC1 mRNA
Genes: UIMC1; RAP80; RXRIP110
Study 25806231 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25806291 — Predictive Biomarker (PRD): RORA
Genes: RZRA; ROR1; ROR2; ROR3; NR1F1; ROR-alpha; RORalpha; RORa1
Study 25806291 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25807199 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 25807199 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25807932 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25807932 — Surrogate Endpoint (SUR): Blood pressure
Study 25809824 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25810005 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25819643 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 25820067 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25820067 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25820680 — Surrogate Endpoint (SUR): Blood pressure
Study 25821795 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 25821963 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25821963 — Surrogate Endpoint (SUR): Serum creatinine
Study 25822102 — Predictive Biomarker (PRD): ARMC5 mRNA
Genes: ARMC5
Study 25823737 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 25823737 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25825476 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25825476 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25825476 — Predictive Biomarker (PRD): Hormone receptor
Study 25829400 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25829804 — Surrogate Endpoint (SUR): Bone mineral density
Study 25830321 — Monitoring Biomarker (MOI): Cell-free DNA
Study 25832001 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 25832466 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 25832466 — Surrogate Endpoint (SUR): Serum creatinine
Study 25833826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25833956 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 25833956 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25833956 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25833956 — Safety Biomarker (SAF): Fatty acid binding protein 1
Genes: FABP1; FABPL
Study 25833956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25833956 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25834212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25834952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 25834952 — Monitoring Biomarker (MOI): Cell-free DNA
Study 25837513 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 25838266 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25840034 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25840428 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 25841330 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 25841541 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25841875 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 25847929 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25847929 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 25847929 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 25847936 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25847936 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 25847936 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25847936 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 25849721 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 25849721 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 25849721 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 25849721 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 25850031 — Predictive Biomarker (PRD): CHL1 mRNA
Genes: CHL1; CALL
Study 25850031 — Pharmacodynamic Biomarker (PDY): Neuromodulin
Genes: GAP43
Study 25850031 — Predictive Biomarker (PRD): ITGB3 mRNA
Genes: ITGB3; GP3A
Study 25850031 — Predictive Biomarker (PRD): ELAVL4 mRNA
Genes: ELAVL4; HUD; PNEM
Study 25850031 — Predictive Biomarker (PRD): ITGB1 mRNA
Genes: ITGB1; FNRB; MDF2; MSK12
Study 25850031 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 25851633 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25852054 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 25852054 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25852820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25852820 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25852820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25852820 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25852820 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study 25852820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25852820 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 25852820 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25852820 — Predictive Biomarker (PRD): BLNK mRNA
Genes: BLNK; BASH; SLP65
Study 25852820 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 25853747 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study 25853747 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 25853841 — Surrogate Endpoint (SUR): Blood pressure
Study 25856546 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 25858519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25858546 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25860107 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 25861459 — Predictive Biomarker (PRD): HERC5 mRNA
Genes: HERC5; CEB1; CEBP1
Study 25861459 — Predictive Biomarker (PRD): CMPK2 mRNA
Genes: CMPK2
Study 25861459 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 25861459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25862716 — Surrogate Endpoint (SUR): Blood pressure
Study 25864160 — Predictive Biomarker (PRD): BCL2A1 mRNA
Genes: BCL2A1; BCL2L5; BFL1; GRS; HBPA1
Study 25865468 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25867537 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25869198 — Surrogate Endpoint (SUR): Blood pressure
Study 25869737 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 25869737 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 25870087 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25872787 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 25873979 — Predictive Biomarker (PRD): DMBT1 mRNA
Genes: DMBT1; GP340
Study 25874001 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 25874991 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25876560 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 25876560 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study 25877635 — Predictive Biomarker (PRD): MX1 mRNA
Genes: MX1
Study 25877635 — Predictive Biomarker (PRD): IFI27 mRNA
Genes: IFI27