TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20588058 — Surrogate Endpoint (SUR): Serum creatinine
Study 16887213 — Surrogate Endpoint (SUR): Blood pressure
Study 10594527 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10594527 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10594527 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2085344 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 17453591 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15212115 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 10857213 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 9088884 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 3899418 — Surrogate Endpoint (SUR): Blood pressure
Study 29587770 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29587770 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29587770 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24315979 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 2526824 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28407722 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 24684808 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 31468214 — Surrogate Endpoint (SUR): Blood pressure
Study 28831954 — Predictive Biomarker (PRD): Hormone receptor
Study 16313817 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 6184562 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6184562 — Surrogate Endpoint (SUR): Blood pressure
Study 17529914 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 17529914 — Surrogate Endpoint (SUR): Blood pressure
Study 3317338 — Surrogate Endpoint (SUR): Blood pressure
Study 28399981 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 20824894 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 20824894 — Surrogate Endpoint (SUR): Sperm parameters
Study 15624283 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 15624283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27357530 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20726885 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study 18258986 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 11212064 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11212064 — Surrogate Endpoint (SUR): Blood pressure
Study 11212064 — Surrogate Endpoint (SUR): Serum creatinine
Study 31445454 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 31445454 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29247141 — Predictive Biomarker (PRD): HDAC9 mRNA
Genes: HDAC9; HDAC7; HDAC7B; HDRP; KIAA0744; MITR
Study 27177240 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24479409 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 12422299 — Surrogate Endpoint (SUR): Blood pressure
Study 26553084 — Monitoring Biomarker (MOI): Procalcitonin
Study 19857748 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3907396 — Surrogate Endpoint (SUR): Blood pressure
Study 1465791 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15983179 — Surrogate Endpoint (SUR): Bone mineral density
Study 29527478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29527478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 25518300 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 15731556 — Surrogate Endpoint (SUR): Blood pressure
Study 27839852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18449422 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 14517521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3277558 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3277558 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20850959 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2732064 — Surrogate Endpoint (SUR): Blood pressure
Study 29246240 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 29246240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29246240 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 29246240 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29246240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21554710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21554710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29530072 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29530072 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 27055193 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27055193 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15994013 — Predictive Biomarker (PRD): KY mRNA
Genes: KY
Study 15463813 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 24859205 — Predictive Biomarker (PRD): CACNA1G mRNA
Genes: CACNA1G; KIAA1123
Study 24859205 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 24859205 — Predictive Biomarker (PRD): RUNX3 mRNA
Genes: RUNX3; AML2; CBFA3; PEBP2A3
Study 24859205 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 24859205 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 8980774 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27309537 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 2354706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 2354706 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 18707755 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16145306 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8834093 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 6946753 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 31856374 — Surrogate Endpoint (SUR): Serum creatinine
Study 25354238 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2405743 — Surrogate Endpoint (SUR): Blood pressure
Study 31369328 — Surrogate Endpoint (SUR): Blood pressure
Study 12373267 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 9649456 — Surrogate Endpoint (SUR): Bone mineral density
Study 22248747 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study 18803000 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 7318347 — Surrogate Endpoint (SUR): Blood pressure
Study 27352487 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 25342209 — Surrogate Endpoint (SUR): Blood pressure
Study 25342209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22719882 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 22719882 — Surrogate Endpoint (SUR): Bone mineral density
Study 29426328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29426328 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29426328 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19013564 — Surrogate Endpoint (SUR): Bone mineral density
Study 18784156 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 18784156 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 1280091 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 31159799 — Surrogate Endpoint (SUR): Blood pressure
Study 28026887 — Surrogate Endpoint (SUR): Blood pressure
Study 21246067 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 17096115 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 7916004 — Surrogate Endpoint (SUR): Blood pressure
Study 7890023 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31854098 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 11738071 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11738071 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25308771 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15088420 — Surrogate Endpoint (SUR): Blood pressure
Study 8201382 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 28899715 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 28899715 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 28899715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28577679 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23146065 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 6210180 — Surrogate Endpoint (SUR): Blood pressure
Study 20625082 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 20625082 — Surrogate Endpoint (SUR): Blood pressure
Study 9661567 — Surrogate Endpoint (SUR): Blood pressure
Study 25707611 — Surrogate Endpoint (SUR): Bone mineral density
Study 14604716 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 9012637 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9012637 — Surrogate Endpoint (SUR): Blood pressure
Study 27846743 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27846743 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 27846743 — Predictive Biomarker (PRD): AMACR mRNA
Genes: AMACR
Study 27846743 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24520880 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20884019 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17498886 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7905523 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24393553 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15185228 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 1410747 — Surrogate Endpoint (SUR): Blood pressure
Study 19133017 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19133017 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 15893540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25455721 — Surrogate Endpoint (SUR): Blood pressure
Study 27068399 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8856618 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 1731034 — Surrogate Endpoint (SUR): Serum sodium
Study 16030367 — Surrogate Endpoint (SUR): Blood pressure
Study 31097732 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27085785 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 25134822 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21975559 — Surrogate Endpoint (SUR): Bone mineral density
Study 12067329 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 10220831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23321318 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 20031848 — Surrogate Endpoint (SUR): Blood pressure
Study 15140323 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7982445 — Surrogate Endpoint (SUR): Bone mineral density
Study 23454402 — Surrogate Endpoint (SUR): Serum sodium
Study 22142351 — Surrogate Endpoint (SUR): Blood pressure
Study 3555016 — Surrogate Endpoint (SUR): Serum creatinine
Study 10669153 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9322469 — Surrogate Endpoint (SUR): Blood pressure
Study 3517650 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15359055 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 8004731 — Surrogate Endpoint (SUR): Blood pressure
Study 15231512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15231512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15231512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23751132 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 9223394 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8477565 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23905378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21448208 — Surrogate Endpoint (SUR): Blood pressure
Study 16979636 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 16979636 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 15570766 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 29858411 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 12073205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9673439 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 9673439 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28701593 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 22974973 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 21375794 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 16998292 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16998292 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 1288905 — Surrogate Endpoint (SUR): Blood pressure
Study 31927671 — Surrogate Endpoint (SUR): Blood pressure
Study 31927671 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20233524 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11802751 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11802751 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31243685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31243685 — Surrogate Endpoint (SUR): Blood pressure
Study 24165976 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 24165976 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 24165976 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 9607385 — Surrogate Endpoint (SUR): Blood pressure
Study 24081373 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7579485 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17715838 — Surrogate Endpoint (SUR): Bone mineral density
Study 10449212 — Surrogate Endpoint (SUR): Blood pressure
Study 7449793 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15475040 — Surrogate Endpoint (SUR): Bone mineral density
Study 28597542 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 28597542 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 28597542 — Predictive Biomarker (PRD): Tubulin beta-3 chain
Genes: TUBB3; TUBB4
Study 28597542 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 26015316 — Surrogate Endpoint (SUR): Blood pressure
Study 21814190 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 17552954 — Surrogate Endpoint (SUR): Serum testosterone
Study 9509564 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9509564 — Surrogate Endpoint (SUR): Serum creatinine
Study 8092504 — Surrogate Endpoint (SUR): Blood pressure
Study 23544105 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 11843736 — Surrogate Endpoint (SUR): Blood pressure
Study 9515282 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3511861 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 28419992 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 15049988 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 9149606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9149606 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8498093 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 16557544 — Monitoring Biomarker (MOI): HBV DNA
Study 26916095 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26916095 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16891014 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16891014 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16891014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16891014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16891014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30837253 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 22810303 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27856497 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23512917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23512917 — Surrogate Endpoint (SUR): Blood pressure
Study 9752892 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9752892 — Surrogate Endpoint (SUR): Blood pressure
Study 20372874 — Surrogate Endpoint (SUR): Blood pressure
Study 18756750 — Surrogate Endpoint (SUR): Blood pressure
Study 10588467 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10588467 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10588467 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10588467 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9432569 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17646220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17646220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17646220 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15486518 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15486518 — Surrogate Endpoint (SUR): Blood pressure
Study 9544745 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2841885 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31718828 — Surrogate Endpoint (SUR): Serum testosterone
Study 28611092 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 15557392 — Surrogate Endpoint (SUR): Blood pressure
Study 1816196 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 444355 — Surrogate Endpoint (SUR): Blood pressure
Study 21073330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21073330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16953374 — Surrogate Endpoint (SUR): Bone mineral density
Study 11458482 — Surrogate Endpoint (SUR): Blood pressure
Study 31037359 — Surrogate Endpoint (SUR): Bone mineral density
Study 28573932 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30599145 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 24119192 — Predictive Biomarker (PRD): WNT2 mRNA
Genes: WNT2; INT1L1; IRP
Study 22665541 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22665541 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28342282 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 12660125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10773060 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10773060 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 10773060 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 10773060 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 1469516 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11078235 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11078235 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27061740 — Surrogate Endpoint (SUR): Blood pressure
Study 17912635 — Predictive Biomarker (PRD): Hormone receptor
Study 30371299 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15908042 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 31358008 — Surrogate Endpoint (SUR): Bone mineral density
Study 24284096 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 19741202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15520061 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9930042 — Surrogate Endpoint (SUR): Blood pressure
Study 7528307 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR