TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31042670 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23568480 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17245770 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 9135694 — Surrogate Endpoint (SUR): Serum testosterone
Study 31842394 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28337705 — Safety Biomarker (SAF): Reactive oxygen species
Study 20139661 — Surrogate Endpoint (SUR): Blood pressure
Study 16162259 — Predictive Biomarker (PRD): CACNA1A mRNA
Genes: CACNA1A; CACH4; CACN3; CACNL1A4
Study 12552492 — Surrogate Endpoint (SUR): Serum creatinine
Study 7222869 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 31837079 — Predictive Biomarker (PRD): GDA mRNA
Genes: GDA; KIAA1258
Study 30730438 — Surrogate Endpoint (SUR): Blood pressure
Study 23374729 — Predictive Biomarker (PRD): ATAD2 mRNA
Genes: ATAD2; L16; PRO2000
Study 11116286 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 11116286 — Surrogate Endpoint (SUR): Blood pressure
Study 8173852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8173852 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24018781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24018781 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 24018781 — Surrogate Endpoint (SUR): Blood pressure
Study 24018781 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20957980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 19025266 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10916104 — Safety Biomarker (SAF): Reactive oxygen species
Study 24615429 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17560879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17560879 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12829911 — Surrogate Endpoint (SUR): Bone mineral density
Study 26638010 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19234056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31569168 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 25089264 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 20934714 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 12517685 — Surrogate Endpoint (SUR): Blood pressure
Study 22659218 — Monitoring Biomarker (MOI): HBV DNA
Study 19592029 — Surrogate Endpoint (SUR): Blood pressure
Study 29804638 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25564211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14576732 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 29476687 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29476687 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22925134 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 20854235 — Surrogate Endpoint (SUR): Blood pressure
Study 12663723 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 8234999 — Surrogate Endpoint (SUR): Blood pressure
Study 19160529 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19160529 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10912666 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 12141373 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30997153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30997153 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 26243249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9834207 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9834207 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7814826 — Surrogate Endpoint (SUR): Blood pressure
Study 2536644 — Surrogate Endpoint (SUR): Serum creatinine
Study 22189843 — Surrogate Endpoint (SUR): Blood pressure
Study 22189843 — Surrogate Endpoint (SUR): Serum creatinine
Study 8757422 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25606785 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15154663 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9842405 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31573612 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16753387 — Surrogate Endpoint (SUR): Urinary oxalate
Study 14749743 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11166743 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2782945 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30439359 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 19244175 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 26374833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26374833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26374833 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26374833 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21525519 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 11220879 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1492862 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 18571914 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12860355 — Safety Biomarker (SAF): DRD3
Study 7721604 — Surrogate Endpoint (SUR): Blood pressure
Study 29074818 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29074818 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30885685 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 11727735 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study 11727735 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31626317 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31626317 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21212378 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17611132 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 1451724 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29994882 — Surrogate Endpoint (SUR): Blood pressure
Study 24013685 — Surrogate Endpoint (SUR): Serum creatinine
Study 10657266 — Surrogate Endpoint (SUR): Blood pressure
Study 21490622 — Surrogate Endpoint (SUR): Blood pressure
Study 10665721 — Surrogate Endpoint (SUR): Bone mineral density
Study 8886909 — Surrogate Endpoint (SUR): Serum creatinine
Study 3000139 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24694205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 18565127 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 18565127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16004610 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 16004610 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16004610 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 16004610 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 6355047 — Surrogate Endpoint (SUR): Serum creatinine
Study 27582622 — Predictive Biomarker (PRD): DDN mRNA
Genes: DDN; KIAA0749
Study 17219106 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17219106 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26218845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23999693 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17952073 — Predictive Biomarker (PRD): TSHR mRNA
Genes: TSHR; LGR3
Study 17952073 — Predictive Biomarker (PRD): FCRL3 mRNA
Genes: FCRL3; FCRH3; IFGP3; IRTA3; SPAP2
Study 3299442 — Surrogate Endpoint (SUR): Blood pressure
Study 24767476 — Surrogate Endpoint (SUR): Blood pressure
Study 20973966 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 20973966 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10660868 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 7848024 — Surrogate Endpoint (SUR): Blood pressure
Study 31134436 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31134436 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 31134436 — Predictive Biomarker (PRD): DSPP mRNA
Genes: DSPP
Study 26539982 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26539982 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 26539982 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 7524833 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 7524833 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 30152527 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 23982695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23982695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23982695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26306861 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 26306861 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 26306861 — Predictive Biomarker (PRD): LEG1 mRNA
Genes: LEG1; C6orf58
Study 26306861 — Predictive Biomarker (PRD): BPIFB1 mRNA
Genes: BPIFB1; C20orf114; LPLUNC1; UNQ706/PRO1357
Study 18940276 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7546754 — Surrogate Endpoint (SUR): Blood pressure
Study 705282 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 25959558 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 21085031 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21085031 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 8428787 — Surrogate Endpoint (SUR): Blood pressure
Study 22928785 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8779366 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1738219 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31537194 — Surrogate Endpoint (SUR): Blood pressure
Study 28945652 — Safety Biomarker (SAF): Hyaluronic acid
Study 27165064 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27165064 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 25072616 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23359971 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 12502011 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7530173 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 20810109 — Surrogate Endpoint (SUR): Serum creatinine
Study 20810109 — Surrogate Endpoint (SUR): Blood pressure
Study 20810109 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1883119 — Surrogate Endpoint (SUR): Bone mineral density
Study 8679756 — Surrogate Endpoint (SUR): Blood pressure
Study 1888695 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30133928 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 25098981 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22212648 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 15498373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 3934544 — Surrogate Endpoint (SUR): Blood pressure
Study 26359449 — Predictive Biomarker (PRD): AGBL2 mRNA
Genes: AGBL2; CCP2
Study 17583595 — Surrogate Endpoint (SUR): Blood pressure
Study 27262302 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20652463 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 15755866 — Surrogate Endpoint (SUR): Bone mineral density
Study 2447403 — Surrogate Endpoint (SUR): Blood pressure
Study 24121497 — Surrogate Endpoint (SUR): Blood pressure
Study 24121497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22561596 — Surrogate Endpoint (SUR): Blood pressure
Study 15356967 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 2840815 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16129844 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11166906 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9499214 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 21158953 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30006513 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30006513 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 7670648 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7670648 — Surrogate Endpoint (SUR): Blood pressure
Study 16350714 — Surrogate Endpoint (SUR): Bone mineral density
Study 16350714 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31248307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29224639 — Surrogate Endpoint (SUR): Blood pressure
Study 20624069 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20624069 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 9209643 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 30024485 — Predictive Biomarker (PRD): BNIP3 mRNA
Genes: BNIP3; NIP3
Study 30024485 — Predictive Biomarker (PRD): RPS6KA1 mRNA
Genes: RPS6KA1; MAPKAPK1A; RSK1
Study 30024485 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 30024485 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 17901414 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16030027 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8678276 — Surrogate Endpoint (SUR): Serum sodium
Study 22276680 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22276680 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 19255158 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 31220991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15854196 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7890057 — Surrogate Endpoint (SUR): Bone mineral density
Study 7890057 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23488307 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11934726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11934726 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25212919 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25212919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25212919 — Safety Biomarker (SAF): BDNF
Study 25212919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10465313 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 19743621 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17082663 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 3030392 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31982885 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 28961678 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16522992 — Surrogate Endpoint (SUR): Blood pressure
Study 9387055 — Surrogate Endpoint (SUR): Bone mineral density
Study 24881730 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15920062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12704548 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12704548 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12704548 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9220308 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7970085 — Surrogate Endpoint (SUR): Blood pressure
Study 22776874 — Surrogate Endpoint (SUR): Blood pressure
Study 18237823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15964747 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 12615677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12615677 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 12615677 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 12615677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12615677 — Predictive Biomarker (PRD): ITGAL mRNA
Genes: ITGAL; CD11A
Study 8869414 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 12386035 — Surrogate Endpoint (SUR): Blood pressure
Study 9797106 — Predictive Biomarker (PRD): SH3PXD2A mRNA
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study 7619663 — Surrogate Endpoint (SUR): Blood pressure
Study 28218380 — Surrogate Endpoint (SUR): Bone mineral density
Study 21911726 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21911726 — Predictive Biomarker (PRD): Hormone receptor
Study 11002384 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1633064 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17302515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25044635 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 11335771 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 9272138 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26045064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26045064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22010225 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 22010225 — Surrogate Endpoint (SUR): Bone mineral density
Study 18971554 — Surrogate Endpoint (SUR): Blood pressure
Study 7697691 — Surrogate Endpoint (SUR): Blood pressure
Study 3316297 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24621064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16702822 — Surrogate Endpoint (SUR): Blood pressure
Study 1329480 — Surrogate Endpoint (SUR): Serum creatinine
Study 1329480 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30558645 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 20632453 — Monitoring Biomarker (MOI): HBV DNA
Study 12053590 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10607712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10607712 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8609227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8609227 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 1360807 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 24408989 — Predictive Biomarker (PRD): CNDP1 mRNA
Genes: CNDP1; CN1; CPGL2; UNQ1915/PRO4380
Study 15647778 — Surrogate Endpoint (SUR): Blood pressure
Study 15647778 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15647778 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15647778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2712272 — Surrogate Endpoint (SUR): Blood pressure
Study 4594580 — Surrogate Endpoint (SUR): Blood pressure
Study 21817198 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8298070 — Surrogate Endpoint (SUR): Blood pressure
Study 3552840 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 9863127 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30888202 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23013888 — Surrogate Endpoint (SUR): Blood pressure
Study 8864546 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 15543337 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1