TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30507710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30507710 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30507710 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28097324 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 28097324 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 3513009 — Surrogate Endpoint (SUR): Blood pressure
Study 20039319 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 20039319 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 20039319 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 8931786 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23302490 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 8218619 — Surrogate Endpoint (SUR): Blood pressure
Study 23926058 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12679215 — Surrogate Endpoint (SUR): Blood pressure
Study 9023710 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2035381 — Surrogate Endpoint (SUR): Blood pressure
Study 7049966 — Surrogate Endpoint (SUR): Blood pressure
Study 30787343 — Surrogate Endpoint (SUR): Blood pressure
Study 30787343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30787343 — Surrogate Endpoint (SUR): Serum calcium
Study 22828593 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19176543 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 19176543 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 31586530 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26497109 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26497109 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9026479 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9026479 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 3903501 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22682339 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 18923386 — Surrogate Endpoint (SUR): Serum calcium
Study 17519730 — Surrogate Endpoint (SUR): Blood pressure
Study 9739441 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 17717114 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15128882 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 31333730 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 15545311 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 775991 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 775991 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11726831 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30176632 — Surrogate Endpoint (SUR): Blood pressure
Study 31833621 — Surrogate Endpoint (SUR): Blood pressure
Study 31833621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21992924 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 15811145 — Surrogate Endpoint (SUR): Blood pressure
Study 15811145 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24423410 — Surrogate Endpoint (SUR): Blood pressure
Study 20137761 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8557972 — Surrogate Endpoint (SUR): Blood pressure
Study 19861511 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 9220212 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7921310 — Surrogate Endpoint (SUR): Blood pressure
Study 3314475 — Surrogate Endpoint (SUR): Serum creatinine
Study 31230020 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 16967045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16967045 — Surrogate Endpoint (SUR): Blood pressure
Study 23615118 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18221509 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17090740 — Surrogate Endpoint (SUR): Bone mineral density
Study 17090740 — Surrogate Endpoint (SUR): Serum creatinine
Study 10741631 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 10741631 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10741631 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29699968 — Predictive Biomarker (PRD): CPQ mRNA
Genes: CPQ; LCH1; PGCP
Study 29699968 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 24096053 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24096053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24096053 — Safety Biomarker (SAF): BDNF
Study 27566263 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27566263 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25349868 — Surrogate Endpoint (SUR): Blood pressure
Study 20492838 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20492838 — Surrogate Endpoint (SUR): Blood pressure
Study 2212374 — Surrogate Endpoint (SUR): Blood pressure
Study 23971711 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23971711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23971711 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23971711 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9177555 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 15745938 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15745938 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 17344325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9022602 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24659155 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16183952 — Predictive Biomarker (PRD): Hormone receptor
Study 23816030 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 8487562 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 3306068 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29362255 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19947898 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20428412 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 1874487 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1874487 — Monitoring Biomarker (MOI): HBV DNA
Study 1874487 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21796410 — Surrogate Endpoint (SUR): Blood pressure
Study 12401632 — Surrogate Endpoint (SUR): Blood pressure
Study 30654808 — Predictive Biomarker (PRD): LUM mRNA
Genes: LUM; LDC; SLRR2D
Study 20094818 — Predictive Biomarker (PRD): STK11 mRNA
Genes: STK11; LKB1; PJS
Study 16006029 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 29426035 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 29426035 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 7223659 — Surrogate Endpoint (SUR): Blood pressure
Study 29890543 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29890543 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 15339752 — Surrogate Endpoint (SUR): Bone mineral density
Study 9667484 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8004302 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 427003 — Surrogate Endpoint (SUR): Serum uric acid
Study 25833348 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 21819564 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 17950802 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15128632 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31277797 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28829204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15617460 — Surrogate Endpoint (SUR): Blood pressure
Study 28883225 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27295199 — Surrogate Endpoint (SUR): Blood pressure
Study 20007337 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10858988 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1847127 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 17371886 — Surrogate Endpoint (SUR): Bone mineral density
Study 9218667 — Surrogate Endpoint (SUR): Blood pressure
Study 3121487 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 27001471 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21808284 — Predictive Biomarker (PRD): EPB41 mRNA
Genes: EPB41; E41P
Study 21808284 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 17619791 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10553821 — Surrogate Endpoint (SUR): Blood pressure
Study 29855695 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21365461 — Surrogate Endpoint (SUR): Bone mineral density
Study 17473917 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 12213868 — Surrogate Endpoint (SUR): Bone mineral density
Study 2515594 — Safety Biomarker (SAF): 51Cr-EDTA
Study 23980846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3121354 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 31190493 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19833270 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19833270 — Surrogate Endpoint (SUR): Blood pressure
Study 29190847 — Predictive Biomarker (PRD): SPTB mRNA
Genes: SPTB; SPTB1
Study 23605883 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18379200 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12909511 — Safety Biomarker (SAF): Hyaluronic acid
Study 1091029 — Surrogate Endpoint (SUR): Serum creatinine
Study 11401920 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 16510656 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10361108 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26209856 — Surrogate Endpoint (SUR): Blood pressure
Study 17087245 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 25921843 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 25921843 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 23032410 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 16957558 — Surrogate Endpoint (SUR): Blood pressure
Study 23116775 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19346844 — Surrogate Endpoint (SUR): Blood pressure
Study 31604428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31604428 — Surrogate Endpoint (SUR): Blood pressure
Study 28772281 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19880463 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 29022212 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29022212 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 29022212 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16884504 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 10943585 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8765432 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 2013559 — Safety Biomarker (SAF): Succinate-semialdehyde dehydrogenase
Genes: ALDH5A1; SSADH
Study 23707139 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 18830041 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18830041 — Surrogate Endpoint (SUR): Bone mineral density
Study 9542555 — Surrogate Endpoint (SUR): Blood pressure
Study 23681030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23681030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21685111 — Surrogate Endpoint (SUR): Blood pressure
Study 19214556 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 15086482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15086482 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15086482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31628490 — Surrogate Endpoint (SUR): Bone mineral density
Study 23382539 — Surrogate Endpoint (SUR): Blood pressure
Study 25115285 — Safety Biomarker (SAF): Hyaluronic acid
Study 15577620 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15577620 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9679818 — Surrogate Endpoint (SUR): Serum creatinine
Study 22007990 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22007990 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 19768804 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9266780 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9266780 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26980363 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26980363 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26980363 — Safety Biomarker (SAF): BDNF
Study 29935641 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 24355800 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 11738299 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9033324 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9033324 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21087856 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 17254453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9625835 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9625835 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8003109 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25423875 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 1725540 — Surrogate Endpoint (SUR): Blood pressure
Study 29477151 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 20175242 — Surrogate Endpoint (SUR): Blood pressure
Study 10497668 — Surrogate Endpoint (SUR): Blood pressure
Study 30846338 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19681414 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 19681414 — Surrogate Endpoint (SUR): Blood pressure
Study 12148711 — Surrogate Endpoint (SUR): Blood pressure
Study 11103054 — Surrogate Endpoint (SUR): Hematologic response
Study 9263612 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 9263612 — Surrogate Endpoint (SUR): Bone mineral density
Study 27125531 — Surrogate Endpoint (SUR): Blood pressure
Study 23298508 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 20399899 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 19478343 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15904630 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7557824 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 6266576 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6266576 — Surrogate Endpoint (SUR): Blood pressure
Study 11879259 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24693973 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 24693973 — Predictive Biomarker (PRD): GCLC mRNA
Genes: GCLC; GLCL; GLCLC
Study 24693973 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 24693973 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 1551969 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 20403733 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16025963 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16025963 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8672762 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 23031172 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 22978725 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 16187232 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26271155 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 10818175 — Surrogate Endpoint (SUR): Blood pressure
Study 8683961 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 29522138 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 29522138 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 29522138 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 12381637 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12381637 — Surrogate Endpoint (SUR): Serum potassium
Study 7760967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15380908 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8560161 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28220020 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28220020 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15914938 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10231057 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 8692532 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1656181 — Surrogate Endpoint (SUR): Blood pressure
Study 31773688 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 31773688 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31773688 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26829066 — Surrogate Endpoint (SUR): Blood pressure
Study 30346819 — Surrogate Endpoint (SUR): Blood pressure
Study 31400517 — Predictive Biomarker (PRD): CRCP mRNA
Genes: CRCP
Study 23024219 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23024219 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 21610514 — Surrogate Endpoint (SUR): Blood pressure
Study 28669666 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28669666 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 28669666 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28669666 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18245121 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8676806 — Surrogate Endpoint (SUR): Blood pressure
Study 30336847 — Surrogate Endpoint (SUR): Serum creatinine
Study 20634666 — Predictive Biomarker (PRD): FCGR2A
Genes: CD32; CD32A; IGFR2; CDw32; Fc-gamma-RIIa; FcgammaRIIa
Study 20634666 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27169789 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23200625 — Surrogate Endpoint (SUR): Serum potassium
Study 2255266 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 376131 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17761370 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23233321 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21245879 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 31221280 — Surrogate Endpoint (SUR): Serum sodium
Study 31221280 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31221280 — Surrogate Endpoint (SUR): Blood pressure
Study 29343128 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 17686441 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15861904 — Surrogate Endpoint (SUR): Blood pressure
Study 7075644 — Surrogate Endpoint (SUR): Blood pressure
Study 30995295 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26815196 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 18159005 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 16185316 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9316434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19804808 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19804808 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 19804808 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 19804808 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 20117364 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7947529 — Surrogate Endpoint (SUR): Blood pressure
Study 3328682 — Surrogate Endpoint (SUR): Blood pressure
Study 31340751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25784512 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14749694 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 3497572 — Surrogate Endpoint (SUR): Serum calcium
Study 29101421 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 29101421 — Surrogate Endpoint (SUR): Serum creatinine
Study 29101421 — Surrogate Endpoint (SUR): Blood pressure
Study 24626137 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12645445 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL