TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1801561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6141186 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30524035 — Surrogate Endpoint (SUR): Blood pressure
Study 27310568 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 17974109 — Predictive Biomarker (PRD): SLA mRNA
Genes: SLA; SLAP; SLAP1
Study 26686968 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 25291577 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 19215005 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25908486 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25908486 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25908486 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24174657 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 17372175 — Surrogate Endpoint (SUR): Blood pressure
Study 29845329 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7619356 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7619356 — Surrogate Endpoint (SUR): Blood pressure
Study 30170468 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30170468 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 30170468 — Surrogate Endpoint (SUR): Blood pressure
Study 22858124 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 22858124 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 18717569 — Safety Biomarker (SAF): Reactive oxygen species
Study 10588987 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21696738 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 21696738 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 16782912 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11119192 — Surrogate Endpoint (SUR): Blood pressure
Study 9194018 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25575541 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 23513469 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 19880138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31189785 — Predictive Biomarker (PRD): EPRS1 mRNA
Genes: EPRS1; EPRS; GLNS; PARS; QARS; QPRS; PIG32
Study 25068884 — Surrogate Endpoint (SUR): Blood pressure
Study 2498507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17582145 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 11874228 — Surrogate Endpoint (SUR): Bone mineral density
Study 30929060 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30929060 — Safety Biomarker (SAF): BDNF
Study 27987385 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 22137082 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16907966 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 9553866 — Safety Biomarker (SAF): Interleukin 1
Study 23884027 — Surrogate Endpoint (SUR): Bone mineral density
Study 8124228 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15144931 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8886633 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 9683394 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9683394 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3154472 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 3154472 — Surrogate Endpoint (SUR): Serum creatinine
Study 23631804 — Surrogate Endpoint (SUR): Blood pressure
Study 19673352 — Surrogate Endpoint (SUR): Bacterial count
Study 17082283 — Surrogate Endpoint (SUR): Blood pressure
Study 31356535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31356535 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31356535 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31356535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31356535 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27552270 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20826253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20826253 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12943892 — Surrogate Endpoint (SUR): Blood pressure
Study 31820601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31820601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31820601 — Safety Biomarker (SAF): Interleukin 1
Study 27798369 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27798369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 27798369 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27798369 — Surrogate Endpoint (SUR): Blood pressure
Study 16504463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16504463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9507382 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9507382 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18962621 — Surrogate Endpoint (SUR): Blood pressure
Study 18962621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18962621 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25010793 — Surrogate Endpoint (SUR): Blood pressure
Study 18834673 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 15236782 — Surrogate Endpoint (SUR): Serum uric acid
Study 15236782 — Surrogate Endpoint (SUR): Blood pressure
Study 15236782 — Surrogate Endpoint (SUR): Serum creatinine
Study 25816031 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 17110814 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 15322328 — Surrogate Endpoint (SUR): Blood pressure
Study 31482684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26133902 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 21200334 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 14961966 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3523663 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31978126 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28857451 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28857451 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 28857451 — Surrogate Endpoint (SUR): Blood pressure
Study 28857451 — Surrogate Endpoint (SUR): Bone mineral density
Study 25341356 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25341356 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25341356 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 12781412 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6744778 — Surrogate Endpoint (SUR): Blood pressure
Study 6744778 — Surrogate Endpoint (SUR): Serum potassium
Study 30702519 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30201853 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22956578 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 2164934 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2164934 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2164934 — Surrogate Endpoint (SUR): Blood pressure
Study 31422390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26574953 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A1 mRNA
Genes: SRD5A1
Study 26574953 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A2 mRNA
Genes: SRD5A2
Study 22368231 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 2534416 — Surrogate Endpoint (SUR): Blood pressure
Study 25722380 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25722380 — Predictive Biomarker (PRD): ERCC5 mRNA
Genes: ERCC5; ERCM2; XPG; XPGC
Study 19333947 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15265052 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22684198 — Surrogate Endpoint (SUR): Blood pressure
Study 29075019 — Surrogate Endpoint (SUR): Blood pressure
Study 21145807 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 28608523 — Surrogate Endpoint (SUR): Blood pressure
Study 20162736 — Surrogate Endpoint (SUR): Blood pressure
Study 31647605 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 31647605 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 31647605 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 28496044 — Surrogate Endpoint (SUR): Serum creatinine
Study 28496044 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16960523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29652792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25518523 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21184675 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 21184675 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 12733733 — Surrogate Endpoint (SUR): Bone mineral density
Study 10100105 — Surrogate Endpoint (SUR): Blood pressure
Study 16323322 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 935836 — Surrogate Endpoint (SUR): Blood pressure
Study 28231371 — Surrogate Endpoint (SUR): Serum creatinine
Study 24164087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24164087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24164087 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24164087 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20634176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20634176 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18250617 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 18250617 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18250617 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 10502210 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10502210 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28810721 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 23030695 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 14643625 — Surrogate Endpoint (SUR): Blood pressure
Study 8596480 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 8596480 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31092118 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 27565045 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25223178 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12297166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12297166 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7733038 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7733038 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26575983 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 19461031 — Surrogate Endpoint (SUR): Blood pressure
Study 19461031 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29246188 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 25342855 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 14575396 — Surrogate Endpoint (SUR): Blood pressure
Study 10599961 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 6264825 — Surrogate Endpoint (SUR): Serum calcium
Study 6264825 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 31477359 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 27396240 — Surrogate Endpoint (SUR): Blood pressure
Study 22608494 — Safety Biomarker (SAF): Reactive oxygen species
Study 22608494 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19095492 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 28645052 — Surrogate Endpoint (SUR): Blood pressure
Study 19881236 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 9471918 — Surrogate Endpoint (SUR): Serum calcium
Study 31957972 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 25530107 — Surrogate Endpoint (SUR): Blood pressure
Study 25530107 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25530107 — Surrogate Endpoint (SUR): Serum sodium
Study 20870757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16812973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7779574 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31708182 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 29367471 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24443059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24443059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20045479 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11856086 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 760750 — Surrogate Endpoint (SUR): Serum sodium
Study 25721604 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25721604 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 25721604 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 25306557 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 25306557 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22039087 — Surrogate Endpoint (SUR): Pathological complete response
Study 12086554 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12086554 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1888324 — Surrogate Endpoint (SUR): Blood pressure
Study 6337951 — Surrogate Endpoint (SUR): Blood pressure
Study 22129616 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22129616 — Surrogate Endpoint (SUR): Blood pressure
Study 9075128 — Surrogate Endpoint (SUR): Blood pressure
Study 8371932 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 29447947 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 12410648 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10514155 — Surrogate Endpoint (SUR): Blood pressure
Study 8792950 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24070494 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8010782 — Surrogate Endpoint (SUR): Serum creatinine
Study 31944277 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31944277 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31944277 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 31944277 — Predictive Biomarker (PRD): CASP3 mRNA
Genes: CASP3; CPP32
Study 16344851 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8968266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1515211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1515211 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1515211 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1515211 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 21344494 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 17583187 — Surrogate Endpoint (SUR): Blood pressure
Study 12377957 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29027653 — Surrogate Endpoint (SUR): Blood pressure
Study 20214329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20214329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20214329 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17612909 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17612909 — Surrogate Endpoint (SUR): Blood pressure
Study 15062889 — Surrogate Endpoint (SUR): Blood pressure
Study 27250715 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 17548730 — Surrogate Endpoint (SUR): Blood pressure
Study 29045553 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27248138 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27248138 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27248138 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20409606 — Monitoring Biomarker (MOI): HBV DNA
Study 10692234 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22857881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20300048 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 20300048 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 20300048 — Surrogate Endpoint (SUR): Blood pressure
Study 24360787 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24360787 — Surrogate Endpoint (SUR): Pathological complete response
Study 22759250 — Safety Biomarker (SAF): Hyaluronic acid
Study 20067650 — Surrogate Endpoint (SUR): Blood pressure
Study 15528979 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24060179 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19208352 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 19208352 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 15363824 — Safety Biomarker (SAF): Reactive oxygen species
Study 15363824 — Surrogate Endpoint (SUR): Blood pressure
Study 15363824 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15363824 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 21872490 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25263395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10805798 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25620670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11773989 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3354490 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 9062617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9062617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29807669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29807669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17024944 — Predictive Biomarker (PRD): FAM53B mRNA
Genes: FAM53B; KIAA0140; SMP
Study 17024944 — Predictive Biomarker (PRD): CLIC1 mRNA
Genes: CLIC1; G6; NCC27
Study 15611806 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10791110 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8369232 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 3465027 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 15592331 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15592331 — Surrogate Endpoint (SUR): Blood pressure
Study 31948091 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study 31948091 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31109906 — Surrogate Endpoint (SUR): Blood pressure
Study 31109906 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12871894 — Surrogate Endpoint (SUR): Bone mineral density
Study 8793795 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 24657218 — Safety Biomarker (SAF): Reactive oxygen species
Study 22196782 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30972702 — Predictive Biomarker (PRD): TOX mRNA
Genes: TOX; KIAA0808
Study 30972702 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study 24622803 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752