TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31228055 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 21754985 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 18697216 — Monitoring Biomarker (MOI): HBV DNA
Study 8026195 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21839983 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 16814411 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27522514 — Surrogate Endpoint (SUR): Blood pressure
Study 23506731 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 3537462 — Surrogate Endpoint (SUR): Serum creatinine
Study 31419322 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24019539 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 8200006 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 2965631 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28860599 — Surrogate Endpoint (SUR): Blood pressure
Study 12124550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31013226 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 30158152 — Safety Biomarker (SAF): Sodium/hydrogen exchanger 3
Genes: SLC9A3; NHE3
Study 15850130 — Surrogate Endpoint (SUR): Blood pressure
Study 10568115 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1868270 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 24047244 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24047244 — Surrogate Endpoint (SUR): Blood pressure
Study 21034619 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 17437965 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10461824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28124127 — Predictive Biomarker (PRD): HK2 mRNA
Genes: HK2
Study 28124127 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 19773751 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study 19773751 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9217714 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25395071 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 25395071 — Surrogate Endpoint (SUR): Bone mineral density
Study 7542134 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17163810 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 9640068 — Surrogate Endpoint (SUR): Blood pressure
Study 30676622 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29975403 — Surrogate Endpoint (SUR): Blood pressure
Study 29975403 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22151064 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 8136443 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 24228535 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8500859 — Surrogate Endpoint (SUR): Serum creatinine
Study 8500859 — Surrogate Endpoint (SUR): Blood pressure
Study 18593491 — Surrogate Endpoint (SUR): Blood pressure
Study 31348053 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21487251 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23423270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 23423270 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 11061773 — Surrogate Endpoint (SUR): Blood pressure
Study 8861677 — Surrogate Endpoint (SUR): Plasma ammonia
Study 1739360 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 6135439 — Surrogate Endpoint (SUR): Blood pressure
Study 26132079 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 24256677 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1534664 — Surrogate Endpoint (SUR): Blood pressure
Study 1534664 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30842257 — Surrogate Endpoint (SUR): Blood pressure
Study 27339848 — Surrogate Endpoint (SUR): Blood pressure
Study 22721353 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 8784219 — Predictive Biomarker (PRD): CLYBL mRNA
Genes: CLYBL; CLB
Study 17489939 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10867779 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25468986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15765440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12422622 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10482930 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30845690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30845690 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19940281 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8092508 — Surrogate Endpoint (SUR): Blood pressure
Study 18433023 — Monitoring Biomarker (MOI): HBV DNA
Study 21636796 — Surrogate Endpoint (SUR): Blood pressure
Study 11309556 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 11309556 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11309556 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 18640769 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12514660 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8807058 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7989477 — Surrogate Endpoint (SUR): Bone mineral density
Study 25925220 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 19306961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31089709 — Predictive Biomarker (PRD): TMPRSS13 mRNA
Genes: TMPRSS13; MSP; TMPRSS11
Study 26330144 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 19725253 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 17964975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30394960 — Surrogate Endpoint (SUR): Blood pressure
Study 27710139 — Surrogate Endpoint (SUR): Blood pressure
Study 23940575 — Surrogate Endpoint (SUR): Blood pressure
Study 28109298 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17407649 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17407649 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 1826239 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28421567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12630974 — Surrogate Endpoint (SUR): Serum potassium
Study 10866717 — Surrogate Endpoint (SUR): Blood pressure
Study 4044293 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 4044293 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 4044293 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11230472 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18276664 — Surrogate Endpoint (SUR): Blood pressure
Study 25057105 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25057105 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25057105 — Surrogate Endpoint (SUR): Serum creatinine
Study 23083772 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 23083772 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29511019 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29511019 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29511019 — Surrogate Endpoint (SUR): Blood pressure
Study 29511019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9394987 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 21519749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21519749 — Monitoring Biomarker (MOI): Complement C4
Study 27941937 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study 15545978 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 12860491 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12860491 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12860491 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29040226 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 16636233 — Surrogate Endpoint (SUR): Blood pressure
Study 30571546 — Surrogate Endpoint (SUR): Blood pressure
Study 19590021 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 3330989 — Surrogate Endpoint (SUR): Blood pressure
Study 28058714 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 24490577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21328025 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8979144 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8979144 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8979144 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 6823952 — Surrogate Endpoint (SUR): Blood pressure
Study 15325416 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 11216930 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8382234 — Surrogate Endpoint (SUR): Blood pressure
Study 23136031 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23136031 — Surrogate Endpoint (SUR): Serum sodium
Study 19996424 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 9005975 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 26494831 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16352688 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9058444 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8436149 — Surrogate Endpoint (SUR): Blood pressure
Study 28008244 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24916694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 24916694 — Predictive Biomarker (PRD): SNAI2 mRNA
Genes: SNAI2; SLUG; SLUGH
Study 24916694 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 24916694 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24916694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 24916694 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18498909 — Surrogate Endpoint (SUR): Blood pressure
Study 1649867 — Surrogate Endpoint (SUR): Blood pressure
Study 29768313 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 29768313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26950829 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21702254 — Surrogate Endpoint (SUR): Blood pressure
Study 25942459 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25942459 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25942459 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 15837759 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 15837759 — Surrogate Endpoint (SUR): Serum creatinine
Study 9839106 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 9839106 — Surrogate Endpoint (SUR): Blood pressure
Study 18212693 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11164205 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 28131706 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 26780278 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 16449518 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 10832669 — Monitoring Biomarker (MOI): HBV DNA
Study 22731800 — Surrogate Endpoint (SUR): Blood pressure
Study 8424426 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14515012 — Surrogate Endpoint (SUR): Urine free cortisol
Study 25465185 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25465185 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 14691684 — Surrogate Endpoint (SUR): Bone mineral density
Study 28500214 — Surrogate Endpoint (SUR): Blood pressure
Study 21355967 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19433391 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17024639 — Surrogate Endpoint (SUR): Blood pressure
Study 2568261 — Surrogate Endpoint (SUR): Blood pressure
Study 29777241 — Surrogate Endpoint (SUR): Blood pressure
Study 16815858 — Surrogate Endpoint (SUR): Serum creatinine
Study 22428464 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18490496 — Surrogate Endpoint (SUR): Blood pressure
Study 2001777 — Surrogate Endpoint (SUR): Blood pressure
Study 31107249 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31107249 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 18042509 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 18042509 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 15882297 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7757311 — Surrogate Endpoint (SUR): Blood pressure
Study 26640058 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 26640058 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 19879683 — Surrogate Endpoint (SUR): Blood pressure
Study 19879683 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30148973 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 27895475 — Surrogate Endpoint (SUR): Blood pressure
Study 20864808 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20864808 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11085324 — Surrogate Endpoint (SUR): Blood pressure
Study 8173687 — Surrogate Endpoint (SUR): Blood pressure
Study 3781686 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21641516 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26848258 — Surrogate Endpoint (SUR): Serum sodium
Study 25340768 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27271310 — Surrogate Endpoint (SUR): Blood pressure
Study 24842156 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21788759 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 15304672 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 31503275 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 23514667 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23514667 — Safety Biomarker (SAF): IL-6 and IL-10
Study 18758684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18758684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18758684 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9163637 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 2490824 — Surrogate Endpoint (SUR): Blood pressure
Study 19931670 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19931670 — Surrogate Endpoint (SUR): Blood pressure
Study 16263778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27079587 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 15188337 — Monitoring Biomarker (MOI): HBV DNA
Study 4629075 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29876777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21219287 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 16461125 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8218099 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6208103 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31083077 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 26936841 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22863642 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16315032 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 16315032 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 16315032 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study 10203414 — Surrogate Endpoint (SUR): Bone mineral density
Study 108461 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 108461 — Surrogate Endpoint (SUR): Blood pressure
Study 30073224 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 25146586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19452483 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16036026 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12432502 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 28075064 — Surrogate Endpoint (SUR): Blood pressure
Study 21836103 — Surrogate Endpoint (SUR): Blood pressure
Study 17215657 — Surrogate Endpoint (SUR): Blood pressure
Study 17215657 — Surrogate Endpoint (SUR): Serum potassium
Study 7921757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31747677 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 16391903 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30443999 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 27246305 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21044248 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17058270 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 471256 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25581163 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 22522672 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 31875646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 24416905 — Predictive Biomarker (PRD): SPAG9 mRNA
Genes: SPAG9; HSS; KIAA0516; MAPK8IP4; SYD1; HLC6
Study 25573347 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25573347 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9200654 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9200654 — Surrogate Endpoint (SUR): Blood pressure
Study 28474361 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1755531 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15022126 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9772930 — Surrogate Endpoint (SUR): Serum creatinine
Study 17023243 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 1794303 — Safety Biomarker (SAF): Hyaluronic acid
Study 3955903 — Surrogate Endpoint (SUR): Blood pressure
Study 3955903 — Surrogate Endpoint (SUR): Serum creatinine
Study 18210330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10608480 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10608480 — Surrogate Endpoint (SUR): Blood pressure
Study 6406531 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 18630541 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19846027 — Surrogate Endpoint (SUR): Serum uric acid
Study 17464087 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15044639 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8519044 — Surrogate Endpoint (SUR): Blood pressure
Study 27424661 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27424661 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22573135 — Surrogate Endpoint (SUR): Blood pressure
Study 22573135 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16640106 — Monitoring Biomarker (MOI): HBV DNA
Study 12503831 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 7937784 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29535280 — Surrogate Endpoint (SUR): Blood pressure
Study 26785764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26785764 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8625682 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26822542 — Surrogate Endpoint (SUR): Blood pressure
Study 25045257 — Surrogate Endpoint (SUR): Bone mineral density
Study 23684438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23684438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19703665 — Surrogate Endpoint (SUR): Blood pressure
Study 25344737 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 7663010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15863491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15863491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23176897 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19271173 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 19271173 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL