TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31699704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31699704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17954368 — Surrogate Endpoint (SUR): Blood pressure
Study 16135167 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 19156155 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19156155 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 14992558 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 10584476 — Surrogate Endpoint (SUR): Blood pressure
Study 9097714 — Surrogate Endpoint (SUR): Serum creatinine
Study 31318392 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31318392 — Predictive Biomarker (PRD): Microsatellite instability
Study 22684565 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22684565 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22684565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22684565 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 22684565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22684565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22684565 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22684565 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15716702 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15716702 — Surrogate Endpoint (SUR): Blood pressure
Study 22339125 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14977992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14977992 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6364778 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 27802843 — Surrogate Endpoint (SUR): Blood pressure
Study 22675288 — Surrogate Endpoint (SUR): Blood pressure
Study 22675288 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17575467 — Surrogate Endpoint (SUR): Serum creatinine
Study 31723064 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 31723064 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20214324 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20214324 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20214324 — Surrogate Endpoint (SUR): Blood pressure
Study 20214324 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20214324 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17855709 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 14985171 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 14985171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11434167 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11434167 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 17122107 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 25604154 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 10652641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10652641 — Safety Biomarker (SAF): Interleukin 1
Study 28338504 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21097402 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21097402 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21097402 — Monitoring Biomarker (MOI): HBV DNA
Study 17277593 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 12374324 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 19085703 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17134951 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17134951 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 25335245 — Surrogate Endpoint (SUR): Blood pressure
Study 9279213 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9279213 — Surrogate Endpoint (SUR): Blood pressure
Study 29024310 — Surrogate Endpoint (SUR): Blood pressure
Study 22462626 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12050248 — Surrogate Endpoint (SUR): Bone mineral density
Study 1712266 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1712266 — Surrogate Endpoint (SUR): Blood pressure
Study 15198882 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15198882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15198882 — Safety Biomarker (SAF): IL-6 and IL-10
Study 25194436 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 16223747 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 16223747 — Surrogate Endpoint (SUR): Bone mineral density
Study 14704844 — Predictive Biomarker (PRD): Hormone receptor
Study 8617412 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8617412 — Surrogate Endpoint (SUR): Blood pressure
Study 30820661 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20101007 — Surrogate Endpoint (SUR): Blood pressure
Study 8678246 — Surrogate Endpoint (SUR): Serum potassium
Study 8678246 — Surrogate Endpoint (SUR): Blood pressure
Study 31020900 — Surrogate Endpoint (SUR): Serum creatinine
Study 28755550 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16267070 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 23307890 — Surrogate Endpoint (SUR): Blood pressure
Study 18174862 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16391891 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 24530993 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 22932169 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11773987 — Surrogate Endpoint (SUR): Blood pressure
Study 11773987 — Surrogate Endpoint (SUR): Serum creatinine
Study 11773987 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27277213 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22923289 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 22923289 — Surrogate Endpoint (SUR): Bone mineral density
Study 18711188 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 15177522 — Surrogate Endpoint (SUR): Blood pressure
Study 8608658 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31102525 — Surrogate Endpoint (SUR): Blood pressure
Study 31131517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31131517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31131517 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31131517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28240587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24287217 — Predictive Biomarker (PRD): PELI1 mRNA
Genes: PELI1; PRISM
Study 26859101 — Predictive Biomarker (PRD): Hormone receptor
Study 18948636 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8731383 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23508601 — Surrogate Endpoint (SUR): Blood pressure
Study 8273956 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 28720336 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23899896 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 23899896 — Predictive Biomarker (PRD): FKBP7 mRNA
Genes: FKBP7; FKBP23; UNQ670/PRO1304
Study 15213617 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 28259499 — Surrogate Endpoint (SUR): Blood pressure
Study 28259499 — Surrogate Endpoint (SUR): Serum uric acid
Study 25702618 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21048776 — Surrogate Endpoint (SUR): Blood pressure
Study 9215837 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 26603740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26603740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24758079 — Surrogate Endpoint (SUR): Bone mineral density
Study 15935090 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 16303936 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 15807201 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8399641 — Surrogate Endpoint (SUR): Serum calcium
Study 28404091 — Monitoring Biomarker (MOI): HBV DNA
Study 28404091 — Surrogate Endpoint (SUR): Bone mineral density
Study 28404091 — Surrogate Endpoint (SUR): Serum creatinine
Study 16012762 — Monitoring Biomarker (MOI): HBV DNA
Study 9397291 — Surrogate Endpoint (SUR): Blood pressure
Study 8394193 — Surrogate Endpoint (SUR): Blood pressure
Study 3720571 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28223274 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 28223274 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 28223274 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 28223274 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 26604731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1799929 — Surrogate Endpoint (SUR): Blood pressure
Study 24850877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24850877 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24850877 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9650013 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9650013 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 28065679 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26398281 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 2195580 — Surrogate Endpoint (SUR): Blood pressure
Study 28657933 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 25998068 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21723353 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9327151 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1105483 — Surrogate Endpoint (SUR): Blood pressure
Study 9230143 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31434935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23426618 — Predictive Biomarker (PRD): IRS2 mRNA
Genes: IRS2
Study 18194401 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 16612399 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 22892751 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 10367619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10367619 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10367619 — Safety Biomarker (SAF): Interleukin 1
Study 10367619 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25867700 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 12028831 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9566670 — Surrogate Endpoint (SUR): Bone mineral density
Study 26566091 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23517933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23517933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2419693 — Surrogate Endpoint (SUR): Blood pressure
Study 30365470 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 25376194 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 22589439 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1738766 — Surrogate Endpoint (SUR): Blood pressure
Study 1738766 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29069507 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29069507 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 19580457 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 11890871 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 8585220 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31337369 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21321491 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 29726282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29726282 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 29726282 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16082607 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31529385 — Predictive Biomarker (PRD): SIRPA mRNA
Genes: SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP
Study 26829661 — Surrogate Endpoint (SUR): Bone mineral density
Study 25103026 — Predictive Biomarker (PRD): RNPEP mRNA
Genes: RNPEP; APB
Study 16234012 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2177062 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2177062 — Surrogate Endpoint (SUR): Blood pressure
Study 389483 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17565514 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17565514 — Surrogate Endpoint (SUR): Blood pressure
Study 26300237 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21569186 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9313755 — Surrogate Endpoint (SUR): Blood pressure
Study 12515870 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1097344 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20673585 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19463464 — Surrogate Endpoint (SUR): Serum creatinine
Study 9405029 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9405029 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9405029 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 26177352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8432773 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 18794654 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 20727239 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20727239 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 2486952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20572767 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 16082528 — Surrogate Endpoint (SUR): Serum creatinine
Study 1826569 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30997816 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 30997816 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29359722 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24965957 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 23818768 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23818768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23818768 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23818768 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 23818768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27802585 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18199844 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18199844 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8627061 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21778151 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 8759084 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 5677210 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25173516 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 351715 — Surrogate Endpoint (SUR): Blood pressure
Study 29959667 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29959667 — Surrogate Endpoint (SUR): Blood pressure
Study 26484463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15196108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15196108 — Safety Biomarker (SAF): Interleukin 1
Study 9649909 — Predictive Biomarker (PRD): OSBP mRNA
Genes: OSBP; OSBP1
Study 9649909 — Surrogate Endpoint (SUR): Blood pressure
Study 8127110 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26545986 — Surrogate Endpoint (SUR): Blood pressure
Study 22475305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28765644 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28765644 — Safety Biomarker (SAF): MTHFR
Study 20008239 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 18041162 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23583219 — Predictive Biomarker (PRD): TNFA
Genes: TNF; TNFSF2; DIF; TNF-alpha
Study 23583219 — Surrogate Endpoint (SUR): Blood pressure
Study 6185343 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 25074351 — Surrogate Endpoint (SUR): Bone mineral density
Study 8704691 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25029202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20385996 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 10197295 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 7551881 — Surrogate Endpoint (SUR): Serum sodium
Study 7551881 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31618905 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31618905 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31618905 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30967424 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 30967424 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29499873 — Surrogate Endpoint (SUR): Blood pressure
Study 17344605 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9756307 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 3048053 — Surrogate Endpoint (SUR): Blood pressure
Study 3048053 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30246187 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12704348 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8807660 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 31999489 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29669604 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 23788750 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23788750 — Predictive Biomarker (PRD): Hormone receptor
Study 16769264 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 9425363 — Surrogate Endpoint (SUR): Serum creatinine
Study 12854090 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12854090 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1725444 — Surrogate Endpoint (SUR): Blood pressure
Study 28177460 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28177460 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 22607698 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 12381339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21252728 — Surrogate Endpoint (SUR): Bone mineral density
Study 31657614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18670365 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16002796 — Surrogate Endpoint (SUR): Blood pressure
Study 16002796 — Safety Biomarker (SAF): MTHFR
Study 8557785 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 1954079 — Surrogate Endpoint (SUR): Serum potassium
Study 6751166 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 23962028 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL