TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15741734 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15741734 — Surrogate Endpoint (SUR): Blood pressure
Study 1720488 — Surrogate Endpoint (SUR): Blood pressure
Study 6754634 — Surrogate Endpoint (SUR): Blood pressure
Study 27321490 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 25147070 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7699528 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31786114 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18306372 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 15653024 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21146687 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11149435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11149435 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15784802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 779006 — Surrogate Endpoint (SUR): Serum creatinine
Study 19180896 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7959572 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23595590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19535421 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 26299226 — Surrogate Endpoint (SUR): Blood pressure
Study 16476160 — Surrogate Endpoint (SUR): Blood pressure
Study 1996926 — Surrogate Endpoint (SUR): Blood pressure
Study 6352280 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31146774 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 17848834 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11855664 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30458684 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 16968802 — Surrogate Endpoint (SUR): Blood pressure
Study 18455656 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18455656 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14509156 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 14509156 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 9612329 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9612329 — Surrogate Endpoint (SUR): Blood pressure
Study 3191000 — Surrogate Endpoint (SUR): Blood pressure
Study 22880108 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22880108 — Safety Biomarker (SAF): BDNF
Study 19249998 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11966951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9497918 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 9497918 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 8097170 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28281457 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23717490 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23717490 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 21389841 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8661976 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 8661976 — Surrogate Endpoint (SUR): Bone mineral density
Study 31824142 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31824142 — Safety Biomarker (SAF): BDNF
Study 31824142 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25855073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25855073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23980084 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21725579 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16362400 — Surrogate Endpoint (SUR): Blood pressure
Study 11055474 — Surrogate Endpoint (SUR): Blood pressure
Study 31581295 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24446022 — Predictive Biomarker (PRD): AHSP mRNA
Genes: AHSP; EDRF; ERAF
Study 10686664 — Surrogate Endpoint (SUR): Blood pressure
Study 31140540 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22954919 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 22954919 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12401757 — Surrogate Endpoint (SUR): Blood pressure
Study 1613829 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6089540 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6089540 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23006657 — Surrogate Endpoint (SUR): Blood pressure
Study 17389624 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25197015 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22458821 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15743397 — Surrogate Endpoint (SUR): Blood pressure
Study 335225 — Surrogate Endpoint (SUR): Serum calcium
Study 22684652 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15174894 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 15174894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15174894 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8507346 — Surrogate Endpoint (SUR): Blood pressure
Study 26546591 — Surrogate Endpoint (SUR): Blood pressure
Study 9034286 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26832658 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26832658 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12374899 — Surrogate Endpoint (SUR): Blood pressure
Study 31253112 — Surrogate Endpoint (SUR): Blood pressure
Study 17224860 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 11686419 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 7943789 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7943789 — Surrogate Endpoint (SUR): Blood pressure
Study 3062257 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 30237584 — Predictive Biomarker (PRD): MSX2 mRNA
Genes: MSX2; HOX8
Study 30237584 — Predictive Biomarker (PRD): LMNTD1 mRNA
Genes: LMNTD1; IFLTD1
Study 30237584 — Predictive Biomarker (PRD): PTPRD mRNA
Genes: PTPRD
Study 23453465 — Surrogate Endpoint (SUR): Blood pressure
Study 20034685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15479482 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10976977 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 9302444 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3540229 — Surrogate Endpoint (SUR): Blood pressure
Study 3540229 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27312945 — Surrogate Endpoint (SUR): Serum testosterone
Study 27312945 — Surrogate Endpoint (SUR): Bone mineral density
Study 24954162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24954162 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24954162 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 20550650 — Surrogate Endpoint (SUR): Blood pressure
Study 20550650 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15953008 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12748666 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7644852 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25605528 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23490237 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8435994 — Surrogate Endpoint (SUR): Blood pressure
Study 30137217 — Predictive Biomarker (PRD): VCAM1 mRNA
Genes: VCAM1
Study 30137217 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10583454 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 10583454 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 31589553 — Surrogate Endpoint (SUR): Blood pressure
Study 31171523 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16087986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31934993 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31934993 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 23704673 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 14990632 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10619583 — Surrogate Endpoint (SUR): Blood pressure
Study 10434353 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2209407 — Surrogate Endpoint (SUR): Blood pressure
Study 31350995 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 31282325 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31282325 — Surrogate Endpoint (SUR): Blood pressure
Study 15059505 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 15059505 — Surrogate Endpoint (SUR): Bone mineral density
Study 15059505 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15059505 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11586032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 9638964 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27453334 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 15447015 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 7647179 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 15064271 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22435280 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22435280 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 22435280 — Surrogate Endpoint (SUR): Blood pressure
Study 30047786 — Surrogate Endpoint (SUR): Blood pressure
Study 26292291 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21716274 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21716274 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 21716274 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 21716274 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 21716274 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 21716274 — Predictive Biomarker (PRD): P2RY12 mRNA
Genes: P2RY12; HORK3
Study 28558859 — Surrogate Endpoint (SUR): Blood pressure
Study 10215647 — Surrogate Endpoint (SUR): Blood pressure
Study 1706607 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24227768 — Surrogate Endpoint (SUR): Blood pressure
Study 2358926 — Surrogate Endpoint (SUR): Bone mineral density
Study 18925978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20724562 — Surrogate Endpoint (SUR): Blood pressure
Study 18424200 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 12540643 — Surrogate Endpoint (SUR): Blood pressure
Study 30256784 — Surrogate Endpoint (SUR): Blood pressure
Study 26833336 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 12059949 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31968351 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31976336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10921014 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2596940 — Surrogate Endpoint (SUR): Blood pressure
Study 2596940 — Surrogate Endpoint (SUR): Serum potassium
Study 31345163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24453924 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 10826457 — Surrogate Endpoint (SUR): Blood pressure
Study 2003591 — Surrogate Endpoint (SUR): Blood pressure
Study 29187584 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 29187584 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24209639 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 2576886 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 17302782 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 19936917 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7839429 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7839429 — Surrogate Endpoint (SUR): Blood pressure
Study 30445461 — Safety Biomarker (SAF): miR-423
Genes: MIR423
Study 8456478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2420106 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 25754845 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 18503589 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 10861335 — Surrogate Endpoint (SUR): Serum creatinine
Study 29524467 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 18602960 — Predictive Biomarker (PRD): CLSTN3 mRNA
Genes: CLSTN3; CS3; KIAA0726
Study 20418370 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10567289 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 20837822 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 29430998 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 28138980 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 21736448 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 16869001 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27159166 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22784346 — Surrogate Endpoint (SUR): Blood pressure
Study 10101924 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16518530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16518530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8400973 — Surrogate Endpoint (SUR): Blood pressure
Study 3037934 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3037934 — Surrogate Endpoint (SUR): Blood pressure
Study 29094444 — Predictive Biomarker (PRD): PIR mRNA
Genes: PIR
Study 24802775 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 24802775 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22508732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18853581 — Surrogate Endpoint (SUR): Serum creatinine
Study 10973843 — Surrogate Endpoint (SUR): Blood pressure
Study 30259623 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28845751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23462720 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 21289328 — Surrogate Endpoint (SUR): Serum sodium
Study 17105757 — Surrogate Endpoint (SUR): Serum sodium
Study 28601821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10736973 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 10736973 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24801452 — Surrogate Endpoint (SUR): Blood pressure
Study 20602892 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20602892 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 10570638 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 2065809 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30702996 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 30702996 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30702996 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15008926 — Predictive Biomarker (PRD): SLA mRNA
Genes: SLA; SLAP; SLAP1
Study 11079508 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31145324 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 11090233 — Surrogate Endpoint (SUR): Bone mineral density
Study 12759722 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12759722 — Surrogate Endpoint (SUR): Serum creatinine
Study 31599955 — Surrogate Endpoint (SUR): Blood pressure
Study 29914380 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 26181766 — Surrogate Endpoint (SUR): Blood pressure
Study 16800988 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9084325 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 1679047 — Surrogate Endpoint (SUR): Blood pressure
Study 7104176 — Surrogate Endpoint (SUR): Serum sodium
Study 31434037 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24493300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9672928 — Surrogate Endpoint (SUR): Blood pressure
Study 26559255 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 25236946 — Surrogate Endpoint (SUR): Blood pressure
Study 22114872 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 20634634 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20634634 — Surrogate Endpoint (SUR): Blood pressure
Study 12081581 — Surrogate Endpoint (SUR): Blood pressure
Study 10360856 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31507061 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 31507061 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 21209230 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19737403 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16288313 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 16288313 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study 16288313 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24308189 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19332193 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 26632754 — Surrogate Endpoint (SUR): Serum creatinine
Study 26632754 — Surrogate Endpoint (SUR): Blood pressure
Study 6318170 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 21088046 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21088046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21097420 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 10444118 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7774832 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 2317911 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7028257 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 17509880 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11810791 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11810791 — Surrogate Endpoint (SUR): Blood pressure
Study 3063286 — Surrogate Endpoint (SUR): Blood pressure
Study 29531290 — Surrogate Endpoint (SUR): Blood pressure
Study 29531290 — Surrogate Endpoint (SUR): Serum creatinine
Study 29531290 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27365521 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18451643 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12676037 — Surrogate Endpoint (SUR): Blood pressure
Study 12676037 — Surrogate Endpoint (SUR): Urine free cortisol
Study 9175116 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 9175116 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 15987848 — Surrogate Endpoint (SUR): Urinary oxalate
Study 12622584 — Surrogate Endpoint (SUR): Blood pressure
Study 30267032 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 18001380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18001380 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2563786 — Surrogate Endpoint (SUR): Blood pressure
Study 21680997 — Surrogate Endpoint (SUR): Blood pressure
Study 15940534 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30870040 — Surrogate Endpoint (SUR): Blood pressure
Study 31595295 — Surrogate Endpoint (SUR): Blood pressure
Study 15766818 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 2199681 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2199681 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17557777 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 17557777 — Surrogate Endpoint (SUR): Serum creatinine
Study 16386537 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16386537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2507435 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 31332655 — Predictive Biomarker (PRD): PC mRNA
Genes: PC