TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9012300 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 2864857 — Surrogate Endpoint (SUR): Blood pressure
Study 30753892 — Safety Biomarker (SAF): miR-22
Genes: MIR22
Study 30753892 — Predictive Biomarker (PRD): miR-19a
Genes: MIR19A
Study 1632390 — Surrogate Endpoint (SUR): Blood pressure
Study 28795387 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16361173 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7923305 — Surrogate Endpoint (SUR): Blood pressure
Study 11811084 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 25830326 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24246588 — Surrogate Endpoint (SUR): Blood pressure
Study 24246588 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16190390 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 10527998 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 7667814 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31274775 — Surrogate Endpoint (SUR): Serum creatinine
Study 31274775 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31274775 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17902062 — Surrogate Endpoint (SUR): Serum potassium
Study 7950508 — Surrogate Endpoint (SUR): Bone mineral density
Study 7950508 — Surrogate Endpoint (SUR): Serum calcium
Study 25020104 — Surrogate Endpoint (SUR): Bacterial count
Study 28478399 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 28478399 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23563576 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21593649 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 21593649 — Predictive Biomarker (PRD): SYN1 mRNA
Genes: SYN1
Study 27734127 — Surrogate Endpoint (SUR): Blood pressure
Study 20977851 — Surrogate Endpoint (SUR): Blood pressure
Study 9456256 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9456256 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8903614 — Surrogate Endpoint (SUR): Blood pressure
Study 11466696 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 10800872 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8822458 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28146063 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23800784 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21297523 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 16964830 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9013400 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 3902238 — Surrogate Endpoint (SUR): Blood pressure
Study 24858423 — Surrogate Endpoint (SUR): Blood pressure
Study 15912390 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15912390 — Surrogate Endpoint (SUR): Blood pressure
Study 2550244 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2550244 — Surrogate Endpoint (SUR): Blood pressure
Study 28859672 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 28859672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10902934 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30699842 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22694045 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 1501561 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 30120772 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19328269 — Surrogate Endpoint (SUR): Blood pressure
Study 16874150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10669155 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 10669155 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10669155 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29350831 — Predictive Biomarker (PRD): MAS1L mRNA
Genes: MAS1L; MRG
Study 16052841 — Surrogate Endpoint (SUR): Blood pressure
Study 10365650 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10365650 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10365650 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 6117682 — Safety Biomarker (SAF): RFC1
Genes: A1; PO-GA; RFC140; MHCBFB
Study 29884593 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18163509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29753732 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29753732 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29753732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29753732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29753732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29753732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29753732 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 29753732 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25342100 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 20033066 — Safety Biomarker (SAF): Interleukin 12
Study 9737555 — Surrogate Endpoint (SUR): Blood pressure
Study 24280475 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 24280475 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24280475 — Surrogate Endpoint (SUR): Blood pressure
Study 21691756 — Surrogate Endpoint (SUR): Blood pressure
Study 19112586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27323611 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 27323611 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27323611 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27323611 — Surrogate Endpoint (SUR): Blood pressure
Study 24777981 — Surrogate Endpoint (SUR): Blood pressure
Study 20600512 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20600512 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9920948 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 9920948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15987428 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 15987428 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 9464197 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 7842768 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22000747 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 20153888 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1643679 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 25185362 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16753318 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 23733374 — Surrogate Endpoint (SUR): Blood pressure
Study 19015346 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 19015346 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17210593 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9358616 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 24561488 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20647773 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15770976 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23501476 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19266265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19266265 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10649155 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10649155 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28660498 — Predictive Biomarker (PRD): Hormone receptor
Study 21512399 — Safety Biomarker (SAF): Urinary microalbumin
Study 31808709 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 26564598 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 26564598 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 26564598 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26564598 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24285618 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 16236039 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7548979 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30777086 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17530638 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17530638 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17530638 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15238592 — Surrogate Endpoint (SUR): Bone mineral density
Study 15238592 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3651528 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 11194979 — Surrogate Endpoint (SUR): Blood pressure
Study 2981088 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26142345 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 15365622 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26416458 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26416458 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23840296 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 23840296 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 23840296 — Predictive Biomarker (PRD): NR1I2 mRNA
Genes: NR1I2; PXR
Study 9024268 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9024268 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14637136 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 10757852 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29558953 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29558953 — Surrogate Endpoint (SUR): Blood pressure
Study 22320186 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22320186 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 12856480 — Safety Biomarker (SAF): Hyaluronic acid
Study 12856480 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29671280 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 11795752 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 31495389 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28130475 — Predictive Biomarker (PRD): ESR1
Genes: NR3A1; Era; ER-alpha
Study 19959692 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 125133 — Surrogate Endpoint (SUR): Blood pressure
Study 28286189 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17538539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17538539 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11688766 — Surrogate Endpoint (SUR): Blood pressure
Study 29131285 — Surrogate Endpoint (SUR): Blood pressure
Study 16035144 — Surrogate Endpoint (SUR): Blood pressure
Study 10037246 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 1823750 — Surrogate Endpoint (SUR): Blood pressure
Study 31688513 — Surrogate Endpoint (SUR): Blood pressure
Study 28684276 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 9513910 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 7652038 — Surrogate Endpoint (SUR): Blood pressure
Study 356078 — Surrogate Endpoint (SUR): Blood pressure
Study 24814691 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 7826567 — Surrogate Endpoint (SUR): Blood pressure
Study 7826567 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30805908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25675201 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 25675201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18937820 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7874855 — Surrogate Endpoint (SUR): Blood pressure
Study 26354729 — Surrogate Endpoint (SUR): Blood pressure
Study 19017467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24714415 — Surrogate Endpoint (SUR): Serum creatinine
Study 20369705 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15687530 — Surrogate Endpoint (SUR): Serum creatinine
Study 27055107 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16093971 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 10969304 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 20537151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18662628 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 1889023 — Surrogate Endpoint (SUR): Blood pressure
Study 30682445 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 30682445 — Predictive Biomarker (PRD): TNC mRNA
Genes: TNC; HXB
Study 30682445 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 22569029 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17915162 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11491175 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24736628 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24736628 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22581064 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22581064 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22581064 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 1693496 — Surrogate Endpoint (SUR): Blood pressure
Study 20015525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20015525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6367617 — Surrogate Endpoint (SUR): Blood pressure
Study 26901812 — Surrogate Endpoint (SUR): Bone mineral density
Study 25281437 — Surrogate Endpoint (SUR): Blood pressure
Study 22458343 — Surrogate Endpoint (SUR): Blood pressure
Study 20147463 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 10410825 — Surrogate Endpoint (SUR): Blood pressure
Study 28027638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28027638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25056567 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 22268365 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 22268365 — Safety Biomarker (SAF): Hepatitis A virus cellular receptor 1
Genes: HAVCR1; KIM1; TIM1; TIMD1
Study 24457404 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20880335 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 9894374 — Surrogate Endpoint (SUR): Blood pressure
Study 23297680 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 1681847 — Surrogate Endpoint (SUR): Serum potassium
Study 1681847 — Surrogate Endpoint (SUR): Blood pressure
Study 16116005 — Surrogate Endpoint (SUR): Blood pressure
Study 28968870 — Surrogate Endpoint (SUR): Blood pressure
Study 7930740 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16678893 — Surrogate Endpoint (SUR): Blood pressure
Study 1580290 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1580290 — Surrogate Endpoint (SUR): Blood pressure
Study 31408467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22873117 — Surrogate Endpoint (SUR): Blood pressure
Study 31368518 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 21704360 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22090467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22090467 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 22090467 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17392718 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 12154266 — Surrogate Endpoint (SUR): Blood pressure
Study 19087002 — Surrogate Endpoint (SUR): Blood pressure
Study 7759725 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29182415 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 23981104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23981104 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23981104 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23981104 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16800990 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16800990 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 16800990 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 7318355 — Surrogate Endpoint (SUR): Blood pressure
Study 27993287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24053900 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19240944 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 17317021 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9479614 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 30753323 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30753323 — Surrogate Endpoint (SUR): Blood pressure
Study 29102979 — Surrogate Endpoint (SUR): Blood pressure
Study 29102979 — Surrogate Endpoint (SUR): Serum uric acid
Study 22198971 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 15598683 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 8871266 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8871266 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19074465 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 19074465 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 11720096 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3479456 — Surrogate Endpoint (SUR): Probing pocket depth
Study 30661507 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2582767 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 25078385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25078385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25399016 — Surrogate Endpoint (SUR): Blood pressure
Study 31424399 — Surrogate Endpoint (SUR): Blood pressure
Study 29029087 — Surrogate Endpoint (SUR): Blood pressure
Study 23033919 — Predictive Biomarker (PRD): IGDCC4 mRNA
Genes: IGDCC4; DDM36; KIAA1628; NOPE
Study 19637968 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 19637968 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 17460547 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study 17460547 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 17460547 — Predictive Biomarker (PRD): CYSLTR1 mRNA
Genes: CYSLTR1; CYSLT1
Study 17460547 — Predictive Biomarker (PRD): CYSLTR2 mRNA
Genes: CYSLTR2; CYSLT2; CYSLT2R; PSEC0146
Study 17460547 — Predictive Biomarker (PRD): PLA2G4A mRNA
Genes: PLA2G4A; CPLA2; PLA2G4
Study 17460547 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 17460547 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17460547 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 17460547 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 15181134 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 3533007 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 20405515 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20405515 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15781794 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 29506909 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29506909 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study 25380994 — Surrogate Endpoint (SUR): Blood pressure
Study 23348641 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23348641 — Surrogate Endpoint (SUR): Blood pressure
Study 20486868 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19064745 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 883006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21991809 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF