TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31894038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31894038 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31894038 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 28120497 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28120497 — Surrogate Endpoint (SUR): Blood pressure
Study 1411408 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1411408 — Surrogate Endpoint (SUR): Blood pressure
Study 25284142 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 20174834 — Surrogate Endpoint (SUR): Blood pressure
Study 18472103 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1959341 — Surrogate Endpoint (SUR): Blood pressure
Study 31119881 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 16395260 — Surrogate Endpoint (SUR): Blood pressure
Study 10935580 — Surrogate Endpoint (SUR): Blood pressure
Study 9008601 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31571089 — Safety Biomarker (SAF): Hyaluronic acid
Study 28922936 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 25694217 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23775581 — Predictive Biomarker (PRD): Liver iron
Study 18971385 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 12588577 — Surrogate Endpoint (SUR): Blood pressure
Study 12588577 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12588577 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11249645 — Safety Biomarker (SAF): Interleukin 1
Study 1804665 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15774255 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 11092992 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1549961 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 1549961 — Surrogate Endpoint (SUR): Serum calcium
Study 12934760 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10651694 — Surrogate Endpoint (SUR): Serum creatinine
Study 10651694 — Surrogate Endpoint (SUR): Blood pressure
Study 1668960 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31567839 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study 29976939 — Predictive Biomarker (PRD): NR1D1 mRNA
Genes: NR1D1; EAR1; HREV; THRAL
Study 29976939 — Predictive Biomarker (PRD): NR1D2 mRNA
Genes: NR1D2
Study 29976939 — Predictive Biomarker (PRD): PER3 mRNA
Genes: PER3; GIG13
Study 19099973 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 29690626 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 29690626 — Surrogate Endpoint (SUR): Blood pressure
Study 27811012 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23577062 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23577062 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21950763 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15467097 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 11344197 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9711470 — Surrogate Endpoint (SUR): Blood pressure
Study 18048583 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3240887 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 20309628 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 8583136 — Monitoring Biomarker (MOI): HBV DNA
Study 31090434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10618942 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 7178821 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31917897 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 30864639 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 28167201 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 29282085 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29282085 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29282085 — Surrogate Endpoint (SUR): Blood pressure
Study 24423343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22154318 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22154318 — Surrogate Endpoint (SUR): Blood pressure
Study 17138722 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 17138722 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 16896737 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9395034 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8383390 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10523367 — Surrogate Endpoint (SUR): Blood pressure
Study 7018187 — Surrogate Endpoint (SUR): Blood pressure
Study 22315807 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 16941338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16941338 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11198484 — Surrogate Endpoint (SUR): Blood pressure
Study 31023762 — Surrogate Endpoint (SUR): Bone mineral density
Study 27195774 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 10814923 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 10814923 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9616817 — Surrogate Endpoint (SUR): Serum potassium
Study 29124773 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29124773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29124773 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27123784 — Predictive Biomarker (PRD): ROCK2 mRNA
Genes: ROCK2; KIAA0619
Study 27123784 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27123784 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27123784 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18725614 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12885745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12885745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31090348 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 31090348 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 12535753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12535753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25146127 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25146127 — Safety Biomarker (SAF): Reactive oxygen species
Study 15863535 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12177686 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12177686 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7549892 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30985996 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30985996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30985996 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18298032 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 15665015 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 31696741 — Surrogate Endpoint (SUR): Blood pressure
Study 21965475 — Predictive Biomarker (PRD): Hormone receptor
Study 19244153 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19244153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9751087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9751087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26961571 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25104273 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25104273 — Surrogate Endpoint (SUR): Serum creatinine
Study 7769406 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7769406 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6114845 — Surrogate Endpoint (SUR): Blood pressure
Study 31025365 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25605861 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19399720 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 24715602 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9727279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9727279 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 9727279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19793858 — Surrogate Endpoint (SUR): Blood pressure
Study 31999839 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 31999839 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 29032638 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 24681657 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24681657 — Surrogate Endpoint (SUR): Blood pressure
Study 22691900 — Surrogate Endpoint (SUR): Blood pressure
Study 8392360 — Surrogate Endpoint (SUR): Serum potassium
Study 21887679 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 10803866 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 9297379 — Surrogate Endpoint (SUR): Blood pressure
Study 28918543 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 28918543 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 19004308 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 9371207 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 1532198 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 1532198 — Surrogate Endpoint (SUR): Serum calcium
Study 1532198 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27412548 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 24657491 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 24657491 — Surrogate Endpoint (SUR): Blood pressure
Study 16021535 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 11876261 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11876261 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1971503 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27743290 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23981773 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19841999 — Surrogate Endpoint (SUR): Blood pressure
Study 15153841 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15153841 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26787791 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26787791 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 26787791 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 17157654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1832761 — Surrogate Endpoint (SUR): Blood pressure
Study 15655136 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8637342 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 22446996 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22446996 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20155996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30776134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30776134 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 29149379 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 27386647 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 19825910 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19825910 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15005875 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15005875 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15005875 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30821897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30821897 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24620666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15731536 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27984823 — Surrogate Endpoint (SUR): Serum sodium
Study 25456878 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 21270386 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31724348 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19595184 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 15208586 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15208586 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 15208586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15208586 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25232856 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 18432177 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25980345 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23731173 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23731173 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22289524 — Surrogate Endpoint (SUR): Pathological complete response
Study 9245039 — Surrogate Endpoint (SUR): Serum creatinine
Study 8426213 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3011329 — Surrogate Endpoint (SUR): Blood pressure
Study 3011329 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22682471 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 15324522 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3024866 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30485922 — Surrogate Endpoint (SUR): Serum uric acid
Study 24937541 — Surrogate Endpoint (SUR): Blood pressure
Study 30020330 — Surrogate Endpoint (SUR): Blood pressure
Study 24423117 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 24423117 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 9597052 — Surrogate Endpoint (SUR): Blood pressure
Study 2465445 — Surrogate Endpoint (SUR): Blood pressure
Study 18078762 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10644567 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26891216 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26891216 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 26891216 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 26891216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26891216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2361813 — Surrogate Endpoint (SUR): Blood pressure
Study 25567119 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 19660610 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19660610 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9333106 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 25888571 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25888571 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24021286 — Surrogate Endpoint (SUR): Blood pressure
Study 22776634 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31502893 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21392600 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21392600 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19151304 — Surrogate Endpoint (SUR): Blood pressure
Study 15525879 — Surrogate Endpoint (SUR): Bone mineral density
Study 28292340 — Surrogate Endpoint (SUR): Blood pressure
Study 26178497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26178497 — Surrogate Endpoint (SUR): Serum creatinine
Study 26879829 — Surrogate Endpoint (SUR): Blood pressure
Study 23086244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15752371 — Surrogate Endpoint (SUR): Blood pressure
Study 30342855 — Safety Biomarker (SAF): Reactive oxygen species
Study 27255504 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 8707361 — Surrogate Endpoint (SUR): Serum creatinine
Study 8707361 — Surrogate Endpoint (SUR): Serum potassium
Study 24655490 — Surrogate Endpoint (SUR): Blood pressure
Study 24655490 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 12011706 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 341950 — Surrogate Endpoint (SUR): Blood pressure
Study 27788498 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 23910702 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22194781 — Surrogate Endpoint (SUR): Blood pressure
Study 9495661 — Surrogate Endpoint (SUR): Blood pressure
Study 28277811 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7757308 — Surrogate Endpoint (SUR): Blood pressure
Study 11527140 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31411375 — Surrogate Endpoint (SUR): Blood pressure
Study 22746245 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21684478 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 21684478 — Predictive Biomarker (PRD): PNO1 mRNA
Genes: PNO1
Study 18689695 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 18689695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12846597 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 12846597 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12846597 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 58269 — Surrogate Endpoint (SUR): Blood pressure
Study 31068063 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 20075143 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15767770 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 21318572 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 1488936 — Surrogate Endpoint (SUR): Blood pressure
Study 20102918 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31074198 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 31074198 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21041811 — Surrogate Endpoint (SUR): Blood pressure
Study 16306540 — Surrogate Endpoint (SUR): Blood pressure
Study 788749 — Surrogate Endpoint (SUR): Blood pressure
Study 31881340 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30429032 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30429032 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27440535 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24432999 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24432999 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8970830 — Safety Biomarker (SAF): Interleukin 1
Study 1279290 — Surrogate Endpoint (SUR): Blood pressure
Study 3905414 — Surrogate Endpoint (SUR): Blood pressure
Study 31060545 — Surrogate Endpoint (SUR): Blood pressure
Study 26662208 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 22400810 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10509772 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 27761987 — Surrogate Endpoint (SUR): Blood pressure
Study 25591756 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 25591756 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 17444309 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 12450060 — Surrogate Endpoint (SUR): Bone mineral density
Study 29218707 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 29218707 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein