TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19082804 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 24919837 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 22727709 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 22727709 — Predictive Biomarker (PRD): HTR1A mRNA
Genes: HTR1A; ADRB2RL1; ADRBRL1
Study 22727709 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 16115902 — Surrogate Endpoint (SUR): Bone mineral density
Study 10192146 — Surrogate Endpoint (SUR): Serum creatinine
Study 7755223 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11504959 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9267921 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27156698 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24685786 — Surrogate Endpoint (SUR): Bacterial count
Study 10029244 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 7601014 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7601014 — Surrogate Endpoint (SUR): Blood pressure
Study 30980733 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30980733 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28407247 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28407247 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28407247 — Predictive Biomarker (PRD): Hormone receptor
Study 14660050 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14660050 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14660050 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 14660050 — Predictive Biomarker (PRD): ALPK1 mRNA
Genes: ALPK1; KIAA1527; LAK
Study 2879970 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 30500138 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24663049 — Surrogate Endpoint (SUR): Hematologic response
Study 23238861 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23238861 — Surrogate Endpoint (SUR): Blood pressure
Study 30509312 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27329967 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10481920 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8991966 — Surrogate Endpoint (SUR): Blood pressure
Study 2006600 — Surrogate Endpoint (SUR): Blood pressure
Study 24364223 — Surrogate Endpoint (SUR): Bone mineral density
Study 24364223 — Surrogate Endpoint (SUR): Serum calcium
Study 30064406 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 20630128 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 20630128 — Surrogate Endpoint (SUR): Serum calcium
Study 15929959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26993268 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 6251114 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15738537 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15738537 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11943033 — Surrogate Endpoint (SUR): Bone mineral density
Study 24018349 — Surrogate Endpoint (SUR): Bone mineral density
Study 19244932 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 10904241 — Surrogate Endpoint (SUR): Blood pressure
Study 8738587 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1548522 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28921862 — Surrogate Endpoint (SUR): Blood pressure
Study 15928685 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 29745006 — Surrogate Endpoint (SUR): Blood pressure
Study 27198036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9097275 — Monitoring Biomarker (MOI): HBV DNA
Study 22963751 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 16549839 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16549839 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 16549839 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16549839 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16549839 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14680844 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 8788485 — Surrogate Endpoint (SUR): Blood pressure
Study 31855907 — Surrogate Endpoint (SUR): Serum sodium
Study 26628478 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18818415 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 1688970 — Surrogate Endpoint (SUR): Blood pressure
Study 26231885 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23382191 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23382191 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 23382191 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 23382191 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 10758695 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6701732 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29766294 — Surrogate Endpoint (SUR): Blood pressure
Study 22978102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22978102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20576731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20576731 — Monitoring Biomarker (MOI): Procalcitonin
Study 17926797 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17926797 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10657819 — Surrogate Endpoint (SUR): Bone mineral density
Study 11907500 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 21199800 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19767063 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19767063 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19767063 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17474134 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 17474134 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 15141405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15141405 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31197894 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 19695543 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 15964176 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15964176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15964176 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12777959 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12777959 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11783183 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 11783183 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31373919 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27089862 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12825134 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2580183 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2580183 — Surrogate Endpoint (SUR): Blood pressure
Study 30892700 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30892700 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30892700 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 24767584 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 20538187 — Surrogate Endpoint (SUR): Blood pressure
Study 25545673 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25545673 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25545673 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22781891 — Monitoring Biomarker (MOI): Procalcitonin
Study 8695076 — Surrogate Endpoint (SUR): Blood pressure
Study 29991707 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29991707 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 22764197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22764197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17964767 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16580899 — Predictive Biomarker (PRD): PLAT mRNA
Genes: PLAT
Study 16580899 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16580899 — Predictive Biomarker (PRD): TIMP3 mRNA
Genes: TIMP3
Study 16580899 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 11112003 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 26852075 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24369912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 24740935 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 9284428 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9284428 — Surrogate Endpoint (SUR): Blood pressure
Study 31241002 — Surrogate Endpoint (SUR): Blood pressure
Study 25006420 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 29397659 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 25958473 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21336804 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11531834 — Surrogate Endpoint (SUR): Serum creatinine
Study 16814131 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16814131 — Surrogate Endpoint (SUR): Blood pressure
Study 7107115 — Surrogate Endpoint (SUR): Serum creatinine
Study 4025191 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 4025191 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 4025191 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20075928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20075928 — Surrogate Endpoint (SUR): Blood pressure
Study 20075928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20075928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20075928 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18503053 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 18503053 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29415180 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 29415180 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 29415180 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 29415180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29415180 — Safety Biomarker (SAF): Interleukin 1
Study 29415180 — Safety Biomarker (SAF): IL-6 and IL-10
Study 29415180 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27572327 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 25202955 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8952581 — Surrogate Endpoint (SUR): Blood pressure
Study 31907056 — Surrogate Endpoint (SUR): Blood pressure
Study 16951900 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 11745871 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 7678358 — Surrogate Endpoint (SUR): Serum creatinine
Study 31827007 — Surrogate Endpoint (SUR): Blood pressure
Study 27259099 — Surrogate Endpoint (SUR): Blood pressure
Study 23374164 — Predictive Biomarker (PRD): NOX1 mRNA
Genes: NOX1; MOX1; NOH1
Study 23374164 — Predictive Biomarker (PRD): DUOX2 mRNA
Genes: DUOX2; LNOX2; THOX2
Study 11700852 — Surrogate Endpoint (SUR): Serum testosterone
Study 30341969 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 26182832 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 26182832 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20190243 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 20190243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20190243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20190243 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 16634845 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11189684 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 29120968 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29231409 — Surrogate Endpoint (SUR): Bone mineral density
Study 19837518 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8865926 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7898097 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7898097 — Surrogate Endpoint (SUR): Blood pressure
Study 19240374 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 15909856 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8581845 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8581845 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 2632749 — Surrogate Endpoint (SUR): Blood pressure
Study 26162609 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 18071022 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7691013 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 3575603 — Surrogate Endpoint (SUR): Blood pressure
Study 30144429 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study 26563519 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17955457 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 17955457 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 17955457 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 1461083 — Surrogate Endpoint (SUR): Blood pressure
Study 11922403 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11922403 — Surrogate Endpoint (SUR): Blood pressure
Study 25130061 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 25130061 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 25130061 — Predictive Biomarker (PRD): DIO2 mRNA
Genes: DIO2; ITDI2; TXDI2
Study 15001678 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 28488911 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study 21995514 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 8223735 — Surrogate Endpoint (SUR): Blood pressure
Study 27795779 — Surrogate Endpoint (SUR): Blood pressure
Study 29931835 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 26704923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23328380 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23328380 — Surrogate Endpoint (SUR): Blood pressure
Study 18663331 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 11832363 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 11832363 — Surrogate Endpoint (SUR): Serum testosterone
Study 7574861 — Surrogate Endpoint (SUR): Blood pressure
Study 31842936 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 23652751 — Surrogate Endpoint (SUR): Serum creatinine
Study 19152069 — Surrogate Endpoint (SUR): Bone mineral density
Study 3460195 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 31482428 — Predictive Biomarker (PRD): ZBTB7A mRNA
Genes: ZBTB7A; FBI1; LRF; ZBTB7; ZNF857A
Study 31813531 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28038865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19860230 — Surrogate Endpoint (SUR): Blood pressure
Study 16317061 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15583914 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 25964628 — Safety Biomarker (SAF): Hyaluronic acid
Study 14714360 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9927122 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24040847 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 24040847 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 6127172 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26103191 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 22948223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22948223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12368388 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 9650870 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31418258 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28222556 — Surrogate Endpoint (SUR): Blood pressure
Study 25939655 — Surrogate Endpoint (SUR): Blood pressure
Study 23650429 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23650429 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23650429 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15485290 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1542321 — Surrogate Endpoint (SUR): Bone mineral density
Study 26874387 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26874387 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 25253884 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18552399 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 29996843 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12006918 — Predictive Biomarker (PRD): HES1 mRNA
Genes: HES1; BHLHB39; HL; HRY
Study 7881967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7881967 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7881967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2239141 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23264012 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 19207322 — Safety Biomarker (SAF): Hyaluronic acid
Study 17995589 — Surrogate Endpoint (SUR): Serum creatinine
Study 27796666 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21784047 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8695092 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17158592 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12153923 — Surrogate Endpoint (SUR): Blood pressure
Study 31167892 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16814954 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9174971 — Surrogate Endpoint (SUR): Serum creatinine
Study 2412069 — Surrogate Endpoint (SUR): Blood pressure
Study 28869405 — Surrogate Endpoint (SUR): Blood pressure
Study 22782201 — Monitoring Biomarker (MOI): Procalcitonin
Study 20456486 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 20456486 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7595712 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 25884271 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 21829748 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 19780066 — Surrogate Endpoint (SUR): Blood pressure
Study 28463882 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28463882 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28463882 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26133944 — Safety Biomarker (SAF): Hyaluronic acid
Study 20861135 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18806100 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 24135027 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 16703187 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11350112 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11350112 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 11350112 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 31472087 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 15141721 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 27609509 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25218689 — Surrogate Endpoint (SUR): Blood pressure