TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01195818 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04499027 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT00109226 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00109226 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01448317 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01448317 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00552201 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00552201 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT02858102 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT02858102 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00581048 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01077986 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01077986 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03639896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03639896 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT03639896 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03639896 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03639896 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT03639896 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03639896 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study NCT03639896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03639896 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03639896 — Safety Biomarker (SAF): BDNF
Study NCT03216863 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03216863 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01335035 — Predictive Biomarker (PRD): Liver iron
Study NCT02830464 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04544644 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04544644 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01771991 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04469543 — Safety Biomarker (SAF): MTHFR
Study NCT01488461 — Predictive Biomarker (PRD): SLC9A6 mRNA
Genes: SLC9A6; KIAA0267; NHE6
Study NCT01488461 — Predictive Biomarker (PRD): ATCAY mRNA
Genes: ATCAY; KIAA1872
Study NCT02531139 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02012036 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study NCT02754115 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03898271 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT03381781 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT03381781 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT04364451 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02318901 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00821899 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03706768 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT03706768 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study NCT03706768 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT02918591 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04351932 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01136876 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00533546 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT01277822 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02879760 — Predictive Biomarker (PRD): MAGEA3 mRNA
Genes: MAGEA3; MAGE3
Study NCT01836536 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01836536 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04670263 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03731104 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02295228 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT04405999 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01279811 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02408172 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00168649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03480893 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study NCT05169203 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT05169203 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT02122497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02122497 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT00657137 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03912831 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT02827344 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02827344 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02827344 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02200926 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01183429 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01183429 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04502472 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03556670 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00992056 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00428935 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01013324 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01013324 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT01013324 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT00787241 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT00375505 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00375505 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04695470 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04695470 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04695470 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04695470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT04695470 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04695470 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01104545 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01229007 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03528876 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04389710 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03742479 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00033423 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02332512 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02332512 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02332512 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01970319 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04758416 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT04758416 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01738438 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01738438 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00547300 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00226889 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT04319913 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01835301 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT05729997 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02216916 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02216916 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01034059 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01034059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05107063 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00199082 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03226327 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02544880 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT02544880 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT02788084 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04534400 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04579406 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT04579406 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT00720356 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT04013269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04013269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01461499 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04328545 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT02342782 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT05276336 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT05276336 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT03705676 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT03212248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01222039 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT01222039 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT01222039 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study NCT02489695 — Predictive Biomarker (PRD): PRCC mRNA
Genes: PRCC; TPRC
Study NCT01149707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02454946 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT02333513 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT03585725 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT05510466 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01370941 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02220803 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01687543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02417610 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03075306 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01135459 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study NCT01692496 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT01692496 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT01692496 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT01692496 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01692496 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01692496 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT02411084 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02411084 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00725946 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT03885154 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02144571 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT04474197 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT02538653 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study NCT01318967 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00681213 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study NCT02289196 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00247780 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT03763812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01360424 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04594135 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study NCT03398603 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00745550 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT04172597 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04172597 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03437070 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT04522466 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01288170 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03233828 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05746013 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02115828 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study NCT00634075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02369484 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00373646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT03819166 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study NCT01432106 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02883660 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT02883660 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02883660 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT02883660 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02883660 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study NCT00783653 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00452075 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04978233 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03531840 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02361918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02361918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00025610 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study NCT03172299 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03172299 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00484861 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01324713 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02337036 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT02711865 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study NCT00791050 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT04810364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04810364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00229697 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02797184 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01286623 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04042597 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT04042597 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT04042597 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT04042597 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01070940 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02554786 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04445870 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02885636 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02885636 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01150916 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00530569 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03578198 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03428698 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03951805 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03951805 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03638674 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06291337 — Predictive Biomarker (PRD): TAS1R3 mRNA
Genes: TAS1R3; T1R3; TR3
Study NCT03921866 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03921866 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03921866 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04087941 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT03593486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03238755 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02010242 — Predictive Biomarker (PRD): NOX1 mRNA
Genes: NOX1; MOX1; NOH1
Study NCT01548170 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01548170 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01548170 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01548170 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01548170 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00100698 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00516477 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT00516477 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT02352220 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT02352220 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00873041 — Predictive Biomarker (PRD): Liver iron
Study NCT02008916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00460629 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00460629 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00460629 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02628600 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT04666142 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02729844 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04692831 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03503344 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03767348 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03054623 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03340675 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02204085 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT06792240 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02701959 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03491813 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02107703 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02107703 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02107703 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02107703 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02484404 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02947347 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK