TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20558918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16200264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26577936 — Safety Biomarker (SAF): Hyaluronic acid
Study 7648821 — Surrogate Endpoint (SUR): Blood pressure
Study 31712348 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 24063913 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 24063913 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15475033 — Surrogate Endpoint (SUR): Blood pressure
Study 15475033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15475033 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11533101 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 1839436 — Surrogate Endpoint (SUR): Blood pressure
Study 31823475 — Surrogate Endpoint (SUR): Blood pressure
Study 26218785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26218785 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2881183 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21037344 — Surrogate Endpoint (SUR): Bone mineral density
Study 18071725 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 16875157 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 24055512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20001651 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20001651 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 15919685 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10889132 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10889132 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1431255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1431255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2861218 — Surrogate Endpoint (SUR): Blood pressure
Study 16984942 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 18378381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14533985 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10943575 — Surrogate Endpoint (SUR): Blood pressure
Study 24977985 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20483968 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 16298657 — Surrogate Endpoint (SUR): Serum creatinine
Study 7929868 — Surrogate Endpoint (SUR): Blood pressure
Study 27578562 — Surrogate Endpoint (SUR): Blood pressure
Study 23471837 — Surrogate Endpoint (SUR): Blood pressure
Study 19955824 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15545508 — Surrogate Endpoint (SUR): Blood pressure
Study 15670545 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15670545 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26762204 — Predictive Biomarker (PRD): FMO4 mRNA
Genes: FMO4; FMO2
Study 26762204 — Predictive Biomarker (PRD): OSBPL3 mRNA
Genes: OSBPL3; KIAA0704; ORP3; OSBP3
Study 24635342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9704787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22226329 — Surrogate Endpoint (SUR): Blood pressure
Study 12431857 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 378094 — Surrogate Endpoint (SUR): Blood pressure
Study 19679221 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 30860407 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30860407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23965225 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16604824 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29063703 — Predictive Biomarker (PRD): GMCL2 mRNA
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 25483691 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25483691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12830468 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8105737 — Surrogate Endpoint (SUR): Bone mineral density
Study 23809021 — Predictive Biomarker (PRD): OGT mRNA
Genes: OGT
Study 16919533 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 11277275 — Surrogate Endpoint (SUR): Bone mineral density
Study 8085929 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 2670693 — Monitoring Biomarker (MOI): HBV DNA
Study 27898207 — Predictive Biomarker (PRD): TYRO3 mRNA
Genes: TYRO3; BYK; DTK; RSE; SKY; TIF
Study 26066789 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11193131 — Surrogate Endpoint (SUR): Blood pressure
Study 30043979 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8914038 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 19691426 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9052899 — Surrogate Endpoint (SUR): Blood pressure
Study 27769826 — Surrogate Endpoint (SUR): Blood pressure
Study 30223563 — Surrogate Endpoint (SUR): Blood pressure
Study 26650831 — Predictive Biomarker (PRD): Hormone receptor
Study 23403476 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 20626604 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 18852533 — Surrogate Endpoint (SUR): Serum testosterone
Study 18852533 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10899655 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 27100788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27100788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15076794 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 12364430 — Surrogate Endpoint (SUR): Bone mineral density
Study 2534679 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 24004645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2471005 — Surrogate Endpoint (SUR): Blood pressure
Study 22777834 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21482957 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21482957 — Surrogate Endpoint (SUR): Blood pressure
Study 31288004 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 31288004 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 31288004 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study 31288004 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31288004 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31288004 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31288004 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24055444 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 11789280 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 9279969 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9279969 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9279969 — Surrogate Endpoint (SUR): Blood pressure
Study 9279969 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15725916 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12185379 — Surrogate Endpoint (SUR): Blood pressure
Study 26649448 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24443876 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 24443876 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 21816315 — Surrogate Endpoint (SUR): Blood pressure
Study 15206989 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9488624 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3182309 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 31038755 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 31038755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23354008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11683426 — Surrogate Endpoint (SUR): Bone mineral density
Study 30172659 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 20679737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 6990208 — Surrogate Endpoint (SUR): Blood pressure
Study 28316103 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28316103 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28316103 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 28316103 — Surrogate Endpoint (SUR): Bone mineral density
Study 15179792 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 7926350 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 21801977 — Surrogate Endpoint (SUR): Blood pressure
Study 22360820 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16307966 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27143274 — Surrogate Endpoint (SUR): Blood pressure
Study 17184429 — Surrogate Endpoint (SUR): Blood pressure
Study 14607494 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 14607494 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 23995537 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23995537 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21495077 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 14732787 — Surrogate Endpoint (SUR): Blood pressure
Study 8270290 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29024542 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 22079088 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 18973957 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16152825 — Safety Biomarker (SAF): Hyaluronic acid
Study 16152825 — Monitoring Biomarker (MOI): HBV DNA
Study 24438370 — Surrogate Endpoint (SUR): Bone mineral density
Study 22020758 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9526970 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 8011237 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8011237 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8011237 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28736006 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25938807 — Surrogate Endpoint (SUR): Blood pressure
Study 23918952 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22127969 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 18785848 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11266030 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8302442 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25133794 — Surrogate Endpoint (SUR): Blood pressure
Study 25133794 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20159701 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19123322 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19123322 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8733038 — Surrogate Endpoint (SUR): Blood pressure
Study 31426685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31426685 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27825415 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25077364 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25077364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25077364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10453586 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 7530054 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25154849 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 17215846 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 25613308 — Surrogate Endpoint (SUR): Blood pressure
Study 22835005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17365932 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11549204 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11549204 — Surrogate Endpoint (SUR): Blood pressure
Study 25917562 — Surrogate Endpoint (SUR): Blood pressure
Study 22961576 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 12618276 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10887384 — Safety Biomarker (SAF): Reactive oxygen species
Study 20851872 — Surrogate Endpoint (SUR): Blood pressure
Study 17594783 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 29228000 — Surrogate Endpoint (SUR): Blood pressure
Study 25929604 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 21270121 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 19944317 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 8680886 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1880218 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30321272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26968850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26968850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17509067 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26370061 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 26370061 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 26370061 — Surrogate Endpoint (SUR): Serum creatinine
Study 26370061 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 20525842 — Predictive Biomarker (PRD): BTG3 mRNA
Genes: BTG3; ANA; TOB5
Study 16635791 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11127933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8803588 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31444839 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 22721576 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16801644 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 10808681 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10808681 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8797615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22441743 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10099908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28424257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24809429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23026173 — Surrogate Endpoint (SUR): Blood pressure
Study 19740915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16052085 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11791038 — Surrogate Endpoint (SUR): Blood pressure
Study 31301442 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25970146 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25970146 — Safety Biomarker (SAF): Reactive oxygen species
Study 25970146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7653663 — Surrogate Endpoint (SUR): Blood pressure
Study 16154019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9575984 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 610325 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 31781755 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 24237806 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24237806 — Surrogate Endpoint (SUR): Blood pressure
Study 19673667 — Surrogate Endpoint (SUR): Blood pressure
Study 27255463 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 22313068 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 22313068 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19837545 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 19837545 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 12204788 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 8733689 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9357936 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9357936 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 26909489 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 26909489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26909489 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 22989715 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 31307747 — Surrogate Endpoint (SUR): Blood pressure
Study 11093435 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 11093435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9098861 — Predictive Biomarker (PRD): INSR mRNA
Genes: INSR
Study 8416070 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 3544820 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7525359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28431557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26813135 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26813135 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 2669155 — Surrogate Endpoint (SUR): Serum potassium
Study 28151459 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15908654 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 15908654 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 31478963 — Surrogate Endpoint (SUR): Blood pressure
Study 19917571 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12646667 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 29526852 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29526852 — Safety Biomarker (SAF): BDNF
Study 6581492 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 30092411 — Surrogate Endpoint (SUR): Blood pressure
Study 22907609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8595517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8595517 — Safety Biomarker (SAF): Interleukin 1
Study 227571 — Predictive Biomarker (PRD): CCNA2 mRNA
Genes: CCNA2; CCN1; CCNA
Study 21768541 — Surrogate Endpoint (SUR): Blood pressure
Study 17027360 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30439322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30439322 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3111953 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 6152344 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 17938729 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15226323 — Surrogate Endpoint (SUR): Bone mineral density
Study 31074089 — Predictive Biomarker (PRD): miR-17
Genes: MIR17
Study 31074089 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 31074089 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29908436 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20470276 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20470276 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21860339 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6