TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11772575 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26450920 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 11056590 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24849439 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24849439 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24849439 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 24849439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24849439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24849439 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24849439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8607315 — Surrogate Endpoint (SUR): Blood pressure
Study 28118537 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 21814547 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 3823637 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27367159 — Surrogate Endpoint (SUR): Blood pressure
Study 15336780 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15336780 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 15336780 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 9565943 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 2780404 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 26472122 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 11757472 — Surrogate Endpoint (SUR): Blood pressure
Study 9164203 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 9164203 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9164203 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 29864779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29864779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29864779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29864779 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27583648 — Surrogate Endpoint (SUR): Bone mineral density
Study 6097457 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11242608 — Surrogate Endpoint (SUR): Bone mineral density
Study 11242608 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 11242608 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8452386 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 24648266 — Surrogate Endpoint (SUR): Bone mineral density
Study 20979455 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 18568841 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8090332 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 8090332 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30912719 — Surrogate Endpoint (SUR): Bone mineral density
Study 25933487 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24156966 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17014554 — Surrogate Endpoint (SUR): Blood pressure
Study 8973780 — Surrogate Endpoint (SUR): Blood pressure
Study 29099978 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25767259 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 25767259 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25767259 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 1724577 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1724577 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12970287 — Surrogate Endpoint (SUR): Bone mineral density
Study 23530976 — Safety Biomarker (SAF): Hyaluronic acid
Study 21774100 — Surrogate Endpoint (SUR): Blood pressure
Study 15268810 — Monitoring Biomarker (MOI): HBV DNA
Study 7805462 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7805462 — Surrogate Endpoint (SUR): Blood pressure
Study 7805462 — Surrogate Endpoint (SUR): Serum potassium
Study 11049014 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 9052345 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8305650 — Surrogate Endpoint (SUR): Blood pressure
Study 23997095 — Surrogate Endpoint (SUR): Blood pressure
Study 16583466 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 7830026 — Surrogate Endpoint (SUR): Blood pressure
Study 23186831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23186831 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23186831 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23186831 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9136776 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9136776 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 8053664 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 31674161 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31674161 — Safety Biomarker (SAF): BDNF
Study 19110596 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25378931 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 25378931 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 25378931 — Safety Biomarker (SAF): Reactive oxygen species
Study 14687092 — Surrogate Endpoint (SUR): Blood pressure
Study 11593067 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7903966 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26405990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26405990 — Surrogate Endpoint (SUR): Blood pressure
Study 26405990 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26405990 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19744614 — Surrogate Endpoint (SUR): Serum creatinine
Study 9470059 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9470059 — Surrogate Endpoint (SUR): Blood pressure
Study 7911029 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29742924 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 26231288 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 26231288 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21159789 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21159789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21159789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21159789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3534583 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29941309 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14682110 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31493361 — Surrogate Endpoint (SUR): Blood pressure
Study 27791067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27791067 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20309434 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20309434 — Surrogate Endpoint (SUR): Blood pressure
Study 20309434 — Surrogate Endpoint (SUR): Serum creatinine
Study 6794909 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 2669473 — Surrogate Endpoint (SUR): Blood pressure
Study 26348661 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 18475181 — Surrogate Endpoint (SUR): Serum creatinine
Study 18475181 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23317012 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23317012 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30354703 — Surrogate Endpoint (SUR): Blood pressure
Study 25392187 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 21992621 — Surrogate Endpoint (SUR): Blood pressure
Study 22164745 — Surrogate Endpoint (SUR): Blood pressure
Study 15656713 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11355480 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8433137 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2885354 — Surrogate Endpoint (SUR): Blood pressure
Study 29357208 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24254894 — Monitoring Biomarker (MOI): Procalcitonin
Study 24254894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24254894 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 24254894 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24254894 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24254894 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22653986 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17329907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15333311 — Surrogate Endpoint (SUR): Blood pressure
Study 21881478 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2411246 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 26754331 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24590635 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 24590635 — Predictive Biomarker (PRD): Hormone receptor
Study 24590635 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 24590635 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30115103 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30115103 — Surrogate Endpoint (SUR): Blood pressure
Study 25794628 — Surrogate Endpoint (SUR): Blood pressure
Study 8835282 — Surrogate Endpoint (SUR): Blood pressure
Study 1333910 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 20102889 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15821951 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12212053 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8334031 — Surrogate Endpoint (SUR): Bone mineral density
Study 8334031 — Surrogate Endpoint (SUR): Serum calcium
Study 8334031 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31352663 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31352663 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22150686 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9143001 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 23480324 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 10959618 — Surrogate Endpoint (SUR): Urinary oxalate
Study 20211022 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 17372737 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12421100 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12421100 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2698935 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27761000 — Surrogate Endpoint (SUR): Blood pressure
Study 11901038 — Predictive Biomarker (PRD): FGF4 mRNA
Genes: FGF4; HST; HSTF1; KS3
Study 22586900 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12539684 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21303505 — Surrogate Endpoint (SUR): Blood pressure
Study 21303505 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8181019 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11315893 — Surrogate Endpoint (SUR): Blood pressure
Study 29735237 — Surrogate Endpoint (SUR): Bone mineral density
Study 15385341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7855784 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28637708 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23439063 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 23439063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15319332 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 9481614 — Surrogate Endpoint (SUR): Blood pressure
Study 12566871 — Surrogate Endpoint (SUR): Blood pressure
Study 1419616 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 20417063 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 18078614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2292546 — Surrogate Endpoint (SUR): Serum creatinine
Study 7006619 — Surrogate Endpoint (SUR): Blood pressure
Study 31614329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29860661 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29860661 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28450772 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21385856 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study 10809242 — Surrogate Endpoint (SUR): Blood pressure
Study 20003116 — Surrogate Endpoint (SUR): Blood pressure
Study 18160927 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16336289 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 27783162 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21519837 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21519837 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 15339495 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16232156 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 11261739 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11261739 — Surrogate Endpoint (SUR): Blood pressure
Study 1961957 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7597305 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31856909 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 15082280 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15082280 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15082280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10921758 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11416734 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8361472 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20060863 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 21725919 — Predictive Biomarker (PRD): RGL1 mRNA
Genes: RGL1; KIAA0959; RGL
Study 21725919 — Surrogate Endpoint (SUR): Serum creatinine
Study 25713025 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 25713025 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 25713025 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25713025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25713025 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 21504893 — Predictive Biomarker (PRD): EXO1 mRNA
Genes: EXO1; EXOI; HEX1
Study 10945511 — Surrogate Endpoint (SUR): Bone mineral density
Study 23715246 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6430337 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 6430337 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30327358 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29231522 — Predictive Biomarker (PRD): ASPRV1 mRNA
Genes: ASPRV1; SASP
Study 25371536 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20179727 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7865980 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2673438 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 2673438 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 2673438 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 29027108 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 29027108 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 29027108 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 29027108 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 29027108 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29027108 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 15031343 — Surrogate Endpoint (SUR): Bone mineral density
Study 23674608 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8810592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8810592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8810592 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24447183 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15765240 — Surrogate Endpoint (SUR): Blood pressure
Study 21481003 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 9424323 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 3907580 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 16199148 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8520738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8520738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8173702 — Surrogate Endpoint (SUR): Blood pressure
Study 29534403 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 29534403 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16260979 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 10467790 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10467790 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10467790 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7604806 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16116596 — Surrogate Endpoint (SUR): Bone mineral density
Study 10419922 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31002954 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12036860 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 7832595 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17533053 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 17533053 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17533053 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17533053 — Safety Biomarker (SAF): Interleukin 12
Study 9722227 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20379194 — Surrogate Endpoint (SUR): Blood pressure
Study 16091396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11966929 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 30871594 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27789196 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27789196 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 20421832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10974616 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31959339 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25666934 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25666934 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23452148 — Surrogate Endpoint (SUR): Serum creatinine
Study 21352528 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 17537264 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 7988347 — Surrogate Endpoint (SUR): Blood pressure
Study 28566227 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20890666 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7700072 — Surrogate Endpoint (SUR): Blood pressure
Study 15865523 — Surrogate Endpoint (SUR): Serum sodium
Study 23548942 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS