TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20681273 — Surrogate Endpoint (SUR): Blood pressure
Study 14616791 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 14616791 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30114458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30114458 — Surrogate Endpoint (SUR): Bone mineral density
Study 23100508 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 18839047 — Surrogate Endpoint (SUR): Bone mineral density
Study 8556566 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 3908132 — Surrogate Endpoint (SUR): Blood pressure
Study 23730730 — Predictive Biomarker (PRD): CD58 mRNA
Genes: CD58; LFA3
Study 11584877 — Surrogate Endpoint (SUR): Blood pressure
Study 9175047 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9175047 — Surrogate Endpoint (SUR): Blood pressure
Study 7903214 — Surrogate Endpoint (SUR): Blood pressure
Study 20678906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20678906 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10739849 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21652780 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21652780 — Surrogate Endpoint (SUR): Bone mineral density
Study 10971306 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 8607575 — Surrogate Endpoint (SUR): Blood pressure
Study 22311903 — Predictive Biomarker (PRD): NE
Study 22311903 — Surrogate Endpoint (SUR): Blood pressure
Study 20102071 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 12218962 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9846921 — Surrogate Endpoint (SUR): Blood pressure
Study 9175807 — Surrogate Endpoint (SUR): Blood pressure
Study 23375074 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8147063 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3533129 — Surrogate Endpoint (SUR): Serum creatinine
Study 29955032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29955032 — Surrogate Endpoint (SUR): Serum creatinine
Study 22810739 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22810739 — Safety Biomarker (SAF): BDNF
Study 15871020 — Predictive Biomarker (PRD): RBFOX2 mRNA
Genes: RBFOX2; FOX2; HRNBP2; RBM9; RTA
Study 31287141 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29203772 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 29203772 — Predictive Biomarker (PRD): IL1R2 mRNA
Genes: IL1R2; IL1RB
Study 29203772 — Predictive Biomarker (PRD): PPP1R3D mRNA
Genes: PPP1R3D; PPP1R6
Study 29203772 — Predictive Biomarker (PRD): KLHL2 mRNA
Genes: KLHL2
Study 29203772 — Predictive Biomarker (PRD): ECHDC3 mRNA
Genes: ECHDC3; PP1494; PP8332
Study 21868252 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 10812581 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10812581 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31006420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26952125 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 15827573 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 15827573 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 12485320 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9835257 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28687496 — Surrogate Endpoint (SUR): Bone mineral density
Study 15238993 — Surrogate Endpoint (SUR): Blood pressure
Study 8140393 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15221569 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 23780370 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 27480628 — Surrogate Endpoint (SUR): Bone mineral density
Study 27266803 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 15561737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21044308 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 15263905 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 10419078 — Surrogate Endpoint (SUR): Blood pressure
Study 26747438 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17515743 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 18642974 — Safety Biomarker (SAF): DRD2
Study 20129738 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 26294102 — Predictive Biomarker (PRD): ALPI mRNA
Genes: ALPI
Study 23744591 — Surrogate Endpoint (SUR): Serum calcium
Study 20010120 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10924613 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 29522919 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 18803866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21062997 — Predictive Biomarker (PRD): MPG mRNA
Genes: MPG; AAG; ANPG; MID1
Study 21062997 — Surrogate Endpoint (SUR): Blood pressure
Study 11590524 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30342539 — Surrogate Endpoint (SUR): Blood pressure
Study 25099924 — Surrogate Endpoint (SUR): Blood pressure
Study 11802252 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 11802252 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 31236889 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 27270643 — Surrogate Endpoint (SUR): Serum creatinine
Study 22948497 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 7995828 — Surrogate Endpoint (SUR): Blood pressure
Study 22539817 — Surrogate Endpoint (SUR): Serum uric acid
Study 22548691 — Surrogate Endpoint (SUR): Blood pressure
Study 17717224 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 15031786 — Monitoring Biomarker (MOI): HBV DNA
Study 2465437 — Surrogate Endpoint (SUR): Blood pressure
Study 2465437 — Surrogate Endpoint (SUR): Serum testosterone
Study 28330908 — Surrogate Endpoint (SUR): Bone mineral density
Study 25908673 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 19711453 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19711453 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7882602 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9122001 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 9122001 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 22741259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11973193 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19188877 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 15342805 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11773946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11773946 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11773946 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 11773946 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9553680 — Surrogate Endpoint (SUR): Blood pressure
Study 8713783 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30576246 — Predictive Biomarker (PRD): CISH mRNA
Genes: CISH; G18
Study 10225769 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 10225769 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16246964 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12072897 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 12072897 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24763694 — Safety Biomarker (SAF): Reactive oxygen species
Study 3187474 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16205558 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 16205558 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 7749987 — Surrogate Endpoint (SUR): Blood pressure
Study 17651518 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27824234 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27824234 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27824234 — Surrogate Endpoint (SUR): Blood pressure
Study 26717366 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26717366 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22577293 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22577293 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 32007 — Surrogate Endpoint (SUR): Blood pressure
Study 30649176 — Surrogate Endpoint (SUR): Bone mineral density
Study 26362830 — Surrogate Endpoint (SUR): Blood pressure
Study 7797214 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3044068 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31909680 — Surrogate Endpoint (SUR): Blood pressure
Study 26602302 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 24341382 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 24341382 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 24341382 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16484584 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12916867 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25722222 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25722222 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 1514487 — Surrogate Endpoint (SUR): Blood pressure
Study 30765435 — Predictive Biomarker (PRD): GCGR mRNA
Genes: GCGR
Study 15024927 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 6125727 — Surrogate Endpoint (SUR): Blood pressure
Study 24979307 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24979307 — Surrogate Endpoint (SUR): Blood pressure
Study 30817452 — Surrogate Endpoint (SUR): Blood pressure
Study 17564405 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 30063804 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30063804 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24535626 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24535626 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 10442596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15958169 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6782869 — Surrogate Endpoint (SUR): Serum creatinine
Study 6782869 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 24534379 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 30352748 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30352748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30191830 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27130691 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27130691 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 21162959 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21162959 — Surrogate Endpoint (SUR): Blood pressure
Study 17670801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29216945 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 29216945 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10760105 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1569387 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 30634393 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21307868 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21307868 — Surrogate Endpoint (SUR): Blood pressure
Study 21307868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18555744 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18555744 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18555744 — Surrogate Endpoint (SUR): Blood pressure
Study 18555744 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28291486 — Surrogate Endpoint (SUR): Bone mineral density
Study 11093066 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study 8350608 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8678631 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7060323 — Surrogate Endpoint (SUR): Blood pressure
Study 28292758 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 28292758 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 28292758 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 28292758 — Predictive Biomarker (PRD): IRS2 mRNA
Genes: IRS2
Study 28292758 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 28292758 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 25773888 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23462922 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 19098490 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7044523 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24406207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15475601 — Surrogate Endpoint (SUR): Blood pressure
Study 7001898 — Surrogate Endpoint (SUR): Blood pressure
Study 31729126 — Surrogate Endpoint (SUR): Blood pressure
Study 31729126 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16583374 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 1616360 — Surrogate Endpoint (SUR): Bone mineral density
Study 6085189 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31240605 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 10495460 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 30753650 — Surrogate Endpoint (SUR): Blood pressure
Study 22954674 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20082714 — Predictive Biomarker (PRD): INPP5K mRNA
Genes: INPP5K; PPS; SKIP
Study 12232494 — Surrogate Endpoint (SUR): Blood pressure
Study 10421283 — Surrogate Endpoint (SUR): Blood pressure
Study 21268411 — Predictive Biomarker (PRD): CMAS mRNA
Genes: CMAS
Study 17879527 — Surrogate Endpoint (SUR): Serum creatinine
Study 17879527 — Surrogate Endpoint (SUR): Blood pressure
Study 10051803 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22907764 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22907764 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 11282170 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 11282170 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3653122 — Surrogate Endpoint (SUR): Blood pressure
Study 31797417 — Surrogate Endpoint (SUR): Bone mineral density
Study 26327495 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15930485 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15930485 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6367578 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29432383 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16636856 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 11834238 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 18697183 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18697183 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18697183 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16595786 — Surrogate Endpoint (SUR): Blood pressure
Study 12411756 — Surrogate Endpoint (SUR): Serum creatinine
Study 30055883 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 21036743 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21036743 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 21036743 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 21036743 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 28915863 — Surrogate Endpoint (SUR): Blood pressure
Study 23159770 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 18198263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18198263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22340260 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 30186593 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11668667 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31539025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12833465 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 30848697 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28437264 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12924170 — Surrogate Endpoint (SUR): Blood pressure
Study 8331700 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8331700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10896693 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 8941104 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27604993 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24100150 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16052573 — Surrogate Endpoint (SUR): Serum creatinine
Study 24937546 — Surrogate Endpoint (SUR): Serum calcium
Study 16088297 — Surrogate Endpoint (SUR): Blood pressure
Study 16088297 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16088297 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16088297 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31571243 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31571243 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 31571243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31204146 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 28930174 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28930174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21747355 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21747355 — Surrogate Endpoint (SUR): Blood pressure
Study 9129558 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9129558 — Surrogate Endpoint (SUR): Blood pressure
Study 3372076 — Surrogate Endpoint (SUR): Blood pressure
Study 25875447 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7810285 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2843722 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 31308062 — Predictive Biomarker (PRD): KLRD1 mRNA
Genes: KLRD1; CD94
Study 31308062 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study 21632509 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 1627944 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 1627944 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 1627944 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1627944 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 26282726 — Surrogate Endpoint (SUR): Blood pressure
Study 20139920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20139920 — Surrogate Endpoint (SUR): Blood pressure
Study 20139920 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20139920 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20139920 — Surrogate Endpoint (SUR): Serum uric acid
Study 18264747 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12823597 — Monitoring Biomarker (MOI): HBV DNA
Study 6797778 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23715889 — Safety Biomarker (SAF): Hyaluronic acid
Study 11431176 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11431176 — Surrogate Endpoint (SUR): Blood pressure
Study 28596379 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 28596379 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 22224109 — Surrogate Endpoint (SUR): Blood pressure
Study 12876635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12876635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19192047 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30664075 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4