TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20412135 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 791333 — Surrogate Endpoint (SUR): Blood pressure
Study 30952158 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 25945045 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 8292694 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 8292694 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30595364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30595364 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 30595364 — Predictive Biomarker (PRD): NOCT mRNA
Genes: NOCT; CCR4; CCRN4L; NOC
Study 20879879 — Surrogate Endpoint (SUR): Blood pressure
Study 15992643 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12574182 — Surrogate Endpoint (SUR): Bone mineral density
Study 3916369 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17989698 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17989698 — Surrogate Endpoint (SUR): Blood pressure
Study 11004094 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 19878605 — Surrogate Endpoint (SUR): Blood pressure
Study 22192641 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20014133 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 9551875 — Surrogate Endpoint (SUR): Blood pressure
Study 7941939 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 2896555 — Surrogate Endpoint (SUR): Blood pressure
Study 24831517 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24831517 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 24831517 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 21797916 — Surrogate Endpoint (SUR): Serum testosterone
Study 18054753 — Monitoring Biomarker (MOI): HBV DNA
Study 10869895 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20960028 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9135403 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29136032 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23238489 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 31194979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26598458 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 20608995 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20608995 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9049575 — Surrogate Endpoint (SUR): Blood pressure
Study 8103646 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8103646 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 28232046 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17361530 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17361530 — Surrogate Endpoint (SUR): Blood pressure
Study 6137980 — Surrogate Endpoint (SUR): Blood pressure
Study 28174351 — Surrogate Endpoint (SUR): Serum creatinine
Study 28174351 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 14749563 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30260474 — Predictive Biomarker (PRD): Hormone receptor
Study 21095627 — Surrogate Endpoint (SUR): Blood pressure
Study 8217999 — Surrogate Endpoint (SUR): Blood pressure
Study 16001645 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 11802250 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11802250 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7782725 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31718678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27652977 — Surrogate Endpoint (SUR): Pathological complete response
Study 20889139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20889139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18198648 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16402538 — Surrogate Endpoint (SUR): Blood pressure
Study 2757899 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31096576 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 25800548 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30354935 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1992187 — Surrogate Endpoint (SUR): Total kidney volume
Study 31532795 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 21732049 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16904480 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16904480 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 16904480 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16904480 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9441100 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 2453619 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 23250834 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 23250834 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23250834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21571595 — Surrogate Endpoint (SUR): Serum sodium
Study 15380496 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15380496 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2510661 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2510661 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 16219589 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 22048577 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11534893 — Surrogate Endpoint (SUR): Serum potassium
Study 11534893 — Surrogate Endpoint (SUR): Blood pressure
Study 19060515 — Safety Biomarker (SAF): Hyaluronic acid
Study 8977237 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8977237 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 31899888 — Safety Biomarker (SAF): BDNF
Study 20844469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 20844469 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 20844469 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12196460 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 10958810 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 1457117 — Surrogate Endpoint (SUR): Blood pressure
Study 29940986 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23380743 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 23380743 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 21243762 — Predictive Biomarker (PRD): GNAQ mRNA
Genes: GNAQ; GAQ
Study 15718044 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 6391877 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 30267340 — Surrogate Endpoint (SUR): Blood pressure
Study 16846342 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16846342 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12630351 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12630351 — Predictive Biomarker (PRD): CD72 mRNA
Genes: CD72
Study 10853303 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 10853303 — Predictive Biomarker (PRD): UBL4A mRNA
Genes: UBL4A; DXS254E; GDX; UBL4
Study 9114644 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 28335729 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 25774595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25774595 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22152644 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 17988533 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 17988533 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22669627 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 22669627 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 22669627 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22669627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22669627 — Surrogate Endpoint (SUR): Blood pressure
Study 28166613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24705615 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16133653 — Surrogate Endpoint (SUR): Bone mineral density
Study 2189613 — Surrogate Endpoint (SUR): Blood pressure
Study 17208119 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8753940 — Predictive Biomarker (PRD): SP3 mRNA
Genes: SP3
Study 8753940 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 29532416 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 29532416 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19820754 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9217894 — Surrogate Endpoint (SUR): Blood pressure
Study 8453955 — Surrogate Endpoint (SUR): Blood pressure
Study 23905488 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 6882818 — Surrogate Endpoint (SUR): Blood pressure
Study 9427568 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29605029 — Surrogate Endpoint (SUR): Pathological complete response
Study 28545625 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 9214325 — Predictive Biomarker (PRD): KMT2D mRNA
Genes: KMT2D; ALR; MLL2; MLL4
Study 1926059 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 22066824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19749201 — Surrogate Endpoint (SUR): Blood pressure
Study 15849397 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15849397 — Safety Biomarker (SAF): Reactive oxygen species
Study 29762043 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21440548 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 27211082 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 27211082 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 27211082 — Surrogate Endpoint (SUR): Bone mineral density
Study 10826567 — Surrogate Endpoint (SUR): Blood pressure
Study 2561518 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2561518 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30580572 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 25512268 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25512268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22967863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22967863 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12232493 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 6340009 — Surrogate Endpoint (SUR): Serum creatinine
Study 31232088 — Surrogate Endpoint (SUR): Blood pressure
Study 26739725 — Surrogate Endpoint (SUR): Blood pressure
Study 26739725 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25316572 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 19785632 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10418906 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7473472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11594446 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3417081 — Safety Biomarker (SAF): 51Cr-EDTA
Study 31469238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31469238 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31469238 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29072043 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29072043 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 29072043 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 19027322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8549037 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8549037 — Surrogate Endpoint (SUR): Blood pressure
Study 31771921 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26864371 — Surrogate Endpoint (SUR): Blood pressure
Study 15251163 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 24637663 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 24637663 — Surrogate Endpoint (SUR): Blood pressure
Study 19626632 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 31337743 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 11404532 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9404926 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9404926 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3307498 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30826660 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 30826660 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30826660 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30826660 — Predictive Biomarker (PRD): Microsatellite instability
Study 24619624 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22704366 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15896623 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 9003857 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 21611724 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 21611724 — Safety Biomarker (SAF): DRD2
Study 8436464 — Predictive Biomarker (PRD): TYMP mRNA
Genes: TYMP; ECGF1
Study 20399326 — Surrogate Endpoint (SUR): Blood pressure
Study 6756707 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27928636 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27928636 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 27928636 — Surrogate Endpoint (SUR): Serum calcium
Study 17928776 — Surrogate Endpoint (SUR): Blood pressure
Study 28939004 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29504415 — Surrogate Endpoint (SUR): Blood pressure
Study 9375752 — Predictive Biomarker (PRD): RARS1 mRNA
Genes: RARS1; RARS
Study 8385526 — Surrogate Endpoint (SUR): Blood pressure
Study 30027438 — Surrogate Endpoint (SUR): Bone mineral density
Study 24788563 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17876372 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17876372 — Surrogate Endpoint (SUR): Blood pressure
Study 17876372 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8633488 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7929695 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7929695 — Safety Biomarker (SAF): Interleukin 1
Study 7929695 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7929695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26923690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31610152 — Surrogate Endpoint (SUR): Blood pressure
Study 31610152 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31610152 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27432356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23589107 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23589107 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 23589107 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11778923 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25854021 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25854021 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 25854021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25854021 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25854021 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22073385 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19479079 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19479079 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17429101 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24802242 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24802242 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30045424 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30045424 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24228803 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19174534 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 19174534 — Surrogate Endpoint (SUR): Blood pressure
Study 29606103 — Surrogate Endpoint (SUR): Blood pressure
Study 16337497 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31389383 — Surrogate Endpoint (SUR): Hematologic response
Study 24189151 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12107951 — Surrogate Endpoint (SUR): Blood pressure
Study 7590643 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7590643 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 31467066 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27932353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23606983 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8389421 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20232761 — Surrogate Endpoint (SUR): Serum uric acid
Study 20232761 — Surrogate Endpoint (SUR): Blood pressure
Study 27893045 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22504044 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 22504044 — Predictive Biomarker (PRD): FCGR2A mRNA
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 22504044 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19265481 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19213342 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 10553500 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 26979470 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 24739896 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24739896 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15050334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 12492613 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9475328 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26236924 — Monitoring Biomarker (MOI): HBV DNA
Study 26236924 — Surrogate Endpoint (SUR): Serum creatinine
Study 3535814 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3535814 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22369914 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16431379 — Surrogate Endpoint (SUR): Blood pressure
Study 12817910 — Surrogate Endpoint (SUR): Blood pressure
Study 23688422 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 14649610 — Surrogate Endpoint (SUR): Blood pressure
Study 18028530 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 16144892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28039050 — Surrogate Endpoint (SUR): Serum testosterone
Study 26390998 — Surrogate Endpoint (SUR): Blood pressure
Study 21392619 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 31654634 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 24016490 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 21980798 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 15626611 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 12147928 — Surrogate Endpoint (SUR): Blood pressure
Study 7075190 — Surrogate Endpoint (SUR): Serum potassium
Study 21715189 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 9209895 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16607077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2