TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22375409 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24095300 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24095300 — Predictive Biomarker (PRD): Hormone receptor
Study 15153818 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15153818 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10955016 — Surrogate Endpoint (SUR): Blood pressure
Study 8636309 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 1308375 — Surrogate Endpoint (SUR): Serum potassium
Study 22955728 — Surrogate Endpoint (SUR): Blood pressure
Study 9230162 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28391736 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24079752 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 21816543 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 29565949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29565949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27491453 — Predictive Biomarker (PRD): DTL mRNA
Genes: DTL; CDT2; CDW1; DCAF2; L2DTL; RAMP
Study 22250644 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 11699044 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 11699044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19380385 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 9523477 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9523477 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 23044653 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 16267074 — Surrogate Endpoint (SUR): Blood pressure
Study 11245648 — Predictive Biomarker (PRD): HRC mRNA
Genes: HRC; HCP
Study 2431864 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 28177714 — Surrogate Endpoint (SUR): Bone mineral density
Study 23263742 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 23263742 — Predictive Biomarker (PRD): PPARGC1B mRNA
Genes: PPARGC1B; PERC; PGC1; PGC1B; PPARGC1
Study 21511816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21511816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21511816 — Surrogate Endpoint (SUR): Serum creatinine
Study 23020955 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23020955 — Surrogate Endpoint (SUR): Blood pressure
Study 22180399 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 27122462 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27122462 — Surrogate Endpoint (SUR): Blood pressure
Study 20649469 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 18981627 — Surrogate Endpoint (SUR): Blood pressure
Study 11840182 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 29724198 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29724198 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 29724198 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29724198 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18605968 — Surrogate Endpoint (SUR): Blood pressure
Study 10064358 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 6428368 — Surrogate Endpoint (SUR): Blood pressure
Study 20535457 — Surrogate Endpoint (SUR): Serum creatinine
Study 20535457 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 12142116 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7755050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20658527 — Predictive Biomarker (PRD): SERPINF2 mRNA
Genes: SERPINF2; AAP; PLI
Study 27537264 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 27537264 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27537264 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 27537264 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27537264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27537264 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27537264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21918522 — Surrogate Endpoint (SUR): Blood pressure
Study 18830810 — Surrogate Endpoint (SUR): Blood pressure
Study 16609067 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 16609067 — Predictive Biomarker (PRD): FCGR2A mRNA
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 29245201 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22089860 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22089860 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28060186 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12150499 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 18022084 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study 18022084 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 8146894 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3409630 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30989377 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25609219 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16517328 — Surrogate Endpoint (SUR): Blood pressure
Study 11097662 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11097662 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 11097662 — Surrogate Endpoint (SUR): Blood pressure
Study 24936899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24936899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7971289 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 29603851 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23329850 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21465320 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31742897 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12947992 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 31923189 — Surrogate Endpoint (SUR): Blood pressure
Study 31923189 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31923189 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22739069 — Surrogate Endpoint (SUR): Blood pressure
Study 9413873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26474630 — Surrogate Endpoint (SUR): Blood pressure
Study 16250039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30808899 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 23027657 — Surrogate Endpoint (SUR): Blood pressure
Study 12720074 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8781825 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1464341 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1464341 — Surrogate Endpoint (SUR): Blood pressure
Study 6099135 — Surrogate Endpoint (SUR): Blood pressure
Study 19745745 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14960741 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7962339 — Surrogate Endpoint (SUR): Blood pressure
Study 15525889 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 8796773 — Surrogate Endpoint (SUR): Blood pressure
Study 1519607 — Surrogate Endpoint (SUR): Serum creatinine
Study 27098427 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27098427 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27098427 — Predictive Biomarker (PRD): Hepatitis A virus cellular receptor 2
Genes: HAVCR2; TIM3; TIMD3
Study 22149546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22149546 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2156764 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11369255 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26040302 — Surrogate Endpoint (SUR): Blood pressure
Study 17227802 — Surrogate Endpoint (SUR): Bone mineral density
Study 14633757 — Surrogate Endpoint (SUR): Blood pressure
Study 28158398 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28158398 — Surrogate Endpoint (SUR): Blood pressure
Study 25925687 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 16896273 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16896273 — Surrogate Endpoint (SUR): Blood pressure
Study 29064206 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23477634 — Surrogate Endpoint (SUR): Blood pressure
Study 23957631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18496232 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 16569361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12714403 — Safety Biomarker (SAF): Hyaluronic acid
Study 21801403 — Safety Biomarker (SAF): Interleukin 1
Study 9394698 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8497683 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2448863 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 22859357 — Surrogate Endpoint (SUR): Serum creatinine
Study 15877867 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 8730609 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20472916 — Surrogate Endpoint (SUR): Blood pressure
Study 26309217 — Surrogate Endpoint (SUR): Serum creatinine
Study 22003405 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 12846865 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12846865 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10915231 — Surrogate Endpoint (SUR): Blood pressure
Study 29754952 — Surrogate Endpoint (SUR): Blood pressure
Study 18077191 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18077191 — Surrogate Endpoint (SUR): Serum creatinine
Study 9589380 — Surrogate Endpoint (SUR): Blood pressure
Study 29184579 — Surrogate Endpoint (SUR): Blood pressure
Study 20308941 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 15637977 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15637977 — Surrogate Endpoint (SUR): Bacterial count
Study 3349981 — Surrogate Endpoint (SUR): Blood pressure
Study 11694408 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11694408 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27687403 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 12953657 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 12953657 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10848646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 1322162 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1322162 — Surrogate Endpoint (SUR): Serum potassium
Study 1322162 — Surrogate Endpoint (SUR): Serum calcium
Study 12001536 — Safety Biomarker (SAF): Cardiac troponin T
Genes: TNNT2
Study 12001536 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28249141 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 21440872 — Surrogate Endpoint (SUR): Serum creatinine
Study 21440872 — Surrogate Endpoint (SUR): Serum sodium
Study 2859739 — Surrogate Endpoint (SUR): Blood pressure
Study 30130991 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22017169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9282804 — Surrogate Endpoint (SUR): Blood pressure
Study 10898118 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10898118 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24986270 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 20801498 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20801498 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17934448 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 10027360 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 27937053 — Predictive Biomarker (PRD): PEAR1 mRNA
Genes: PEAR1; MEGF12
Study 27937053 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 26310692 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 2572902 — Surrogate Endpoint (SUR): Serum calcium
Study 30771686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17353334 — Predictive Biomarker (PRD): GAMT mRNA
Genes: GAMT
Study 17353334 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 17353334 — Predictive Biomarker (PRD): GATM mRNA
Genes: GATM; AGAT
Study 15347339 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15347339 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 15347339 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9568413 — Surrogate Endpoint (SUR): Blood pressure
Study 9568413 — Surrogate Endpoint (SUR): Serum creatinine
Study 27583439 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 21366694 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 3080575 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 19661218 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 14634864 — Surrogate Endpoint (SUR): Blood pressure
Study 14634864 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11457531 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8004292 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26066384 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26066384 — Surrogate Endpoint (SUR): Blood pressure
Study 23497021 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21576560 — Surrogate Endpoint (SUR): Blood pressure
Study 16765179 — Surrogate Endpoint (SUR): Blood pressure
Study 11903327 — Surrogate Endpoint (SUR): Blood pressure
Study 11903327 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7804515 — Surrogate Endpoint (SUR): Blood pressure
Study 20073218 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 20073218 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 20073218 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 8654625 — Surrogate Endpoint (SUR): Bone mineral density
Study 29757893 — Surrogate Endpoint (SUR): Serum creatinine
Study 21375023 — Surrogate Endpoint (SUR): Blood pressure
Study 18037738 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 18037738 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 16077266 — Surrogate Endpoint (SUR): Blood pressure
Study 7697307 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26641243 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21569994 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30354704 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30354704 — Surrogate Endpoint (SUR): Blood pressure
Study 24770616 — Surrogate Endpoint (SUR): Serum creatinine
Study 16087821 — Surrogate Endpoint (SUR): Bone mineral density
Study 10582134 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10582134 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23174912 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19476471 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 7882821 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7882821 — Surrogate Endpoint (SUR): Blood pressure
Study 26922549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8676224 — Surrogate Endpoint (SUR): Blood pressure
Study 1829902 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12359989 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 901625 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8981202 — Surrogate Endpoint (SUR): Serum creatinine
Study 22984272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22984272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29160000 — Safety Biomarker (SAF): Hyaluronic acid
Study 18568314 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26327301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9367289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19721433 — Predictive Biomarker (PRD): ANKS1B mRNA
Genes: ANKS1B
Study 19721433 — Predictive Biomarker (PRD): CNTNAP5 mRNA
Genes: CNTNAP5; CASPR5
Study 14692430 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10668523 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 27019001 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27019001 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27019001 — Surrogate Endpoint (SUR): Serum testosterone
Study 24285427 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 22323353 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28498853 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2000046 — Surrogate Endpoint (SUR): Blood pressure
Study 6393621 — Surrogate Endpoint (SUR): Blood pressure
Study 21434560 — Surrogate Endpoint (SUR): Blood pressure
Study 15262833 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11697688 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 7920958 — Surrogate Endpoint (SUR): Blood pressure
Study 27147617 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 23727135 — Safety Biomarker (SAF): DRD2
Study 18795630 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 16432682 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11202222 — Surrogate Endpoint (SUR): Bone mineral density
Study 7231666 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 19580960 — Predictive Biomarker (PRD): ACSL1 mRNA
Genes: ACSL1; FACL1; FACL2; LACS; LACS1; LACS2
Study 26272770 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26272770 — Predictive Biomarker (PRD): Hormone receptor
Study 30421393 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27614373 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15224025 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15224025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11759645 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9399611 — Surrogate Endpoint (SUR): Blood pressure
Study 29798889 — Surrogate Endpoint (SUR): Serum creatinine
Study 23615825 — Surrogate Endpoint (SUR): Blood pressure
Study 10344368 — Surrogate Endpoint (SUR): Bone mineral density
Study 8786543 — Surrogate Endpoint (SUR): Blood pressure
Study 20545502 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 15998783 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 10419803 — Surrogate Endpoint (SUR): Blood pressure
Study 6408155 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 6408155 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10458221 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7734907 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26620555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26620555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26620555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18713091 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11014391 — Surrogate Endpoint (SUR): Blood pressure
Study 29893791 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL