TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19540392 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19540392 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9550641 — Surrogate Endpoint (SUR): Blood pressure
Study 30291011 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 30291011 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24375223 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 8831596 — Surrogate Endpoint (SUR): Serum creatinine
Study 30916161 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30916161 — Surrogate Endpoint (SUR): Blood pressure
Study 28451529 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 23046735 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23046735 — Surrogate Endpoint (SUR): Serum creatinine
Study 11736864 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 11736864 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 9431858 — Surrogate Endpoint (SUR): Blood pressure
Study 30415082 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25441015 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23530962 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23530962 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21784145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21784145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15310688 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9627297 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3229297 — Safety Biomarker (SAF): L-acetylcarnitine
Study 28944646 — Surrogate Endpoint (SUR): Blood pressure
Study 26674200 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26674200 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25459392 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 20730060 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20730060 — Surrogate Endpoint (SUR): Blood pressure
Study 20730060 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16183682 — Surrogate Endpoint (SUR): Blood pressure
Study 10391093 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 8873228 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24584876 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 22965699 — Surrogate Endpoint (SUR): Blood pressure
Study 19575284 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18845709 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10202165 — Surrogate Endpoint (SUR): Serum creatinine
Study 30703643 — Predictive Biomarker (PRD): FTL mRNA
Genes: FTL
Study 23553151 — Surrogate Endpoint (SUR): Blood pressure
Study 22162988 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30045595 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 30045595 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11849795 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 11849795 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 30639581 — Safety Biomarker (SAF): Hyaluronic acid
Study 27966572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27966572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21371681 — Surrogate Endpoint (SUR): Blood pressure
Study 19265544 — Surrogate Endpoint (SUR): Blood pressure
Study 15173725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15173725 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 15173725 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15173725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30789855 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 22921446 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 18496812 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9852408 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 29877679 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29877679 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24849105 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20367667 — Safety Biomarker (SAF): Hyaluronic acid
Study 9803985 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8056004 — Surrogate Endpoint (SUR): Blood pressure
Study 31315733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7932194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31980416 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 24662296 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26884557 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 22268183 — Surrogate Endpoint (SUR): Serum creatinine
Study 9809926 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 2692838 — Surrogate Endpoint (SUR): Blood pressure
Study 31145281 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31145281 — Surrogate Endpoint (SUR): Blood pressure
Study 27008585 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23637279 — Surrogate Endpoint (SUR): Blood pressure
Study 12819323 — Surrogate Endpoint (SUR): Serum creatinine
Study 12819323 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25308300 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 17164728 — Surrogate Endpoint (SUR): Serum creatinine
Study 9407377 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 3309901 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 21449914 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 21449914 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 16390852 — Surrogate Endpoint (SUR): Serum creatinine
Study 16390852 — Surrogate Endpoint (SUR): Blood pressure
Study 16390852 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29941296 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 29941296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23378456 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19350339 — Surrogate Endpoint (SUR): Bone mineral density
Study 18242076 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 8576842 — Surrogate Endpoint (SUR): Serum creatinine
Study 2909202 — Surrogate Endpoint (SUR): Serum creatinine
Study 30703258 — Surrogate Endpoint (SUR): Blood pressure
Study 19514864 — Surrogate Endpoint (SUR): Blood pressure
Study 31517745 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 31517745 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 26384014 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28923751 — Surrogate Endpoint (SUR): Blood pressure
Study 20530934 — Predictive Biomarker (PRD): SLC22A5 mRNA
Genes: SLC22A5; OCTN2
Study 15111485 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9041099 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 8282745 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17374416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11427637 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9531074 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20031846 — Surrogate Endpoint (SUR): Blood pressure
Study 17802891 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 14977388 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24585100 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 23801303 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23801303 — Predictive Biomarker (PRD): Hormone receptor
Study 23801303 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23801303 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19038708 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12822744 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10693711 — Surrogate Endpoint (SUR): Serum creatinine
Study 8794412 — Predictive Biomarker (PRD): ALPK1 mRNA
Genes: ALPK1; KIAA1527; LAK
Study 8794412 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3522507 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 18588760 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12069285 — Surrogate Endpoint (SUR): Blood pressure
Study 7830033 — Surrogate Endpoint (SUR): Blood pressure
Study 7830033 — Surrogate Endpoint (SUR): Serum creatinine
Study 7830033 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31915696 — Surrogate Endpoint (SUR): Blood pressure
Study 26048342 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8489054 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2442553 — Surrogate Endpoint (SUR): Blood pressure
Study 26525271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12885371 — Surrogate Endpoint (SUR): Bone mineral density
Study 12885371 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12885371 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1796634 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 30153634 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30153634 — Safety Biomarker (SAF): BDNF
Study 11453889 — Surrogate Endpoint (SUR): Blood pressure
Study 9509448 — Surrogate Endpoint (SUR): Serum calcium
Study 3183367 — Surrogate Endpoint (SUR): Blood pressure
Study 26554758 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26554758 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26554758 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26554758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26554758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26333496 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 21613574 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 1552057 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 22149257 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 22149257 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 22149257 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 18794727 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12127877 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12127877 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8545872 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28928048 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26193635 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1442581 — Surrogate Endpoint (SUR): Blood pressure
Study 20087375 — Surrogate Endpoint (SUR): Blood pressure
Study 11799500 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 10624956 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 28975821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29148893 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 29148893 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 28025434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20567999 — Surrogate Endpoint (SUR): Bone mineral density
Study 31657594 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 23650792 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23650792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23650792 — Surrogate Endpoint (SUR): Blood pressure
Study 11123499 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 14641990 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 1686851 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1686851 — Surrogate Endpoint (SUR): Blood pressure
Study 30047502 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11407649 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7528949 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29495908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19715976 — Surrogate Endpoint (SUR): Serum creatinine
Study 19715976 — Surrogate Endpoint (SUR): Blood pressure
Study 11021450 — Surrogate Endpoint (SUR): Bone mineral density
Study 31120674 — Surrogate Endpoint (SUR): Blood pressure
Study 15276091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15162466 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10985600 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10985600 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19541594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19541594 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 19541594 — Predictive Biomarker (PRD): CDKN1C mRNA
Genes: CDKN1C; KIP2
Study 19541594 — Safety Biomarker (SAF): Interleukin 1
Study 19541594 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 10321661 — Surrogate Endpoint (SUR): Serum sodium
Study 7840824 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7840824 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27575584 — Surrogate Endpoint (SUR): Blood pressure
Study 18680695 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 29075780 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 29075780 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29075780 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29075780 — Safety Biomarker (SAF): Epiregulin
Genes: EREG
Study 29075780 — Safety Biomarker (SAF): Amphiregulin
Genes: AREG; AREGB; SDGF
Study 25060415 — Surrogate Endpoint (SUR): Blood pressure
Study 12870120 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12870120 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 12870120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17597711 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11783195 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27398918 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 25375311 — Surrogate Endpoint (SUR): Blood pressure
Study 12757534 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12757534 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11509470 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30457060 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 28431559 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26562755 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 20708858 — Surrogate Endpoint (SUR): Blood pressure
Study 8394538 — Surrogate Endpoint (SUR): Serum creatinine
Study 22948897 — Surrogate Endpoint (SUR): Blood pressure
Study 14602541 — Surrogate Endpoint (SUR): Blood pressure
Study 10448261 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10448261 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31557067 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 18263674 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16816559 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11068941 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 11068941 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 11068941 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11068941 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2441163 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2441163 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 2441163 — Surrogate Endpoint (SUR): Blood pressure
Study 26242149 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23108194 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23108194 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23108194 — Predictive Biomarker (PRD): VCAM1 mRNA
Genes: VCAM1
Study 23108194 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20530282 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 20530282 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 20530282 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 18222261 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 14688950 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 24187095 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 25712760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25712760 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 14698860 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 8339033 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 24108237 — Surrogate Endpoint (SUR): Blood pressure
Study 22287494 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18164245 — Surrogate Endpoint (SUR): Blood pressure
Study 3923833 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23670305 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 27271657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19793213 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 15066925 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 7534838 — Surrogate Endpoint (SUR): Serum creatinine
Study 7534838 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 17668562 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17668562 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 9586886 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7774334 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28634748 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21122391 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 9211627 — Surrogate Endpoint (SUR): Blood pressure
Study 27589695 — Surrogate Endpoint (SUR): Blood pressure
Study 24160223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16798303 — Surrogate Endpoint (SUR): Blood pressure
Study 27562743 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23736923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23736923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23736923 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 23736923 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12716796 — Surrogate Endpoint (SUR): Serum creatinine
Study 12716796 — Surrogate Endpoint (SUR): Serum potassium
Study 9426079 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 9426079 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30930132 — Surrogate Endpoint (SUR): Blood pressure
Study 12548304 — Surrogate Endpoint (SUR): Serum testosterone
Study 12548304 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12548304 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28069279 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 28069279 — Predictive Biomarker (PRD): LYN mRNA
Genes: LYN; JTK8
Study 12941995 — Surrogate Endpoint (SUR): Blood pressure
Study 11055467 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11055467 — Surrogate Endpoint (SUR): Blood pressure
Study 27988356 — Surrogate Endpoint (SUR): Blood pressure
Study 17926617 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11204938 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 9603128 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 7530064 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 23743809 — Surrogate Endpoint (SUR): Blood pressure
Study 21649813 — Safety Biomarker (SAF): Hyaluronic acid
Study 18319586 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29223479 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29223479 — Surrogate Endpoint (SUR): Pathological complete response
Study 2543201 — Surrogate Endpoint (SUR): Blood pressure
Study 4853634 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids