TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00329485 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00473135 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01935739 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01532791 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05380648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02169518 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study NCT02169518 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04481412 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT01241357 — Predictive Biomarker (PRD): Liver iron
Study NCT02832648 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02517918 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT00868855 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT04071015 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01013285 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00915733 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03438851 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT04251052 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04539496 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04539496 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04539496 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04539496 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01505010 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02334033 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT03772353 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03772353 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03772353 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02997371 — Safety Biomarker (SAF): Interleukin 1
Study NCT01012479 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02539810 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04350944 — Surrogate Endpoint (SUR): Serum calcium
Study NCT00302627 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00302627 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01232504 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00172107 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02756923 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study NCT01172509 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02374021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03078504 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00837408 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02790580 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02672787 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03125213 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04530331 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04530331 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03463148 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01584856 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01681056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02236026 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study NCT02241122 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT03898947 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04424797 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02530853 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01121120 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01808729 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study NCT01924351 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01838252 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01416688 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01416688 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05512897 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02171338 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT00991484 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT02377791 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT03879980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03043313 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03425838 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03425838 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04085627 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01572870 — Predictive Biomarker (PRD): CHIT1 mRNA
Genes: CHIT1
Study NCT01572870 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00880061 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT01720173 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02784028 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02784028 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04215224 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT04147650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT01694355 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04747782 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04747782 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT02376075 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03177551 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00473681 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04487574 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03084224 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT04146181 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT03269526 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00962195 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00962195 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01046279 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03285568 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03285568 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03023449 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04496063 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study NCT04066790 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00240344 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03752099 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT00198952 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00459160 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00295360 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT03090815 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03090815 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03090815 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03090815 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00888433 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01919710 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT00308386 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00652860 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02546167 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT01020448 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT01020448 — Predictive Biomarker (PRD): PCA3
Study NCT01207661 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04052334 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT02367365 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04311060 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYH11 mRNA
Genes: MYH11; KIAA0866
Study NCT04311060 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study NCT04311060 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT04311060 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04311060 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study NCT04311060 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT04311060 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study NCT04311060 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT04311060 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT04311060 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT06168188 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT00621387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03349320 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT03349320 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT00369304 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT03975452 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT03585166 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT01872832 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02824263 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00145925 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00082173 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study NCT02360579 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03186196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03186196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03186196 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT03186196 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT03186196 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01792193 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01792193 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT04029935 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00746590 — Predictive Biomarker (PRD): NQO2 mRNA
Genes: NQO2; NMOR2
Study NCT01973660 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02537535 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02594163 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00171704 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03142763 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04112329 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02259426 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT01917500 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02874079 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study NCT02058043 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT02050230 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02361385 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT05100277 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03423004 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT00890084 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02765607 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02839837 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01353209 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT00696982 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00696982 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00656123 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03507374 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02715167 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01907295 — Predictive Biomarker (PRD): BMPR2 mRNA
Genes: BMPR2; PPH1
Study NCT03970148 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03737123 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03737123 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01480674 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00782184 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00309556 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00000161 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00000161 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02448056 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT00151775 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02539329 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT00445549 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00445549 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01067157 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study NCT04200131 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02669953 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01354808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03602612 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT01183208 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study NCT03311334 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study NCT03311334 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study NCT00429312 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04646590 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04459065 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02832661 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study NCT03093350 — Predictive Biomarker (PRD): MAGEA4 mRNA
Genes: MAGEA4; MAGE4
Study NCT03093350 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study NCT01587807 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study NCT04065997 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01710007 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00150969 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02113696 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04549025 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study NCT03432793 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT03432793 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01067170 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00053157 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02914691 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02914691 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01414777 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01918553 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03216057 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00323297 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02642731 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT02642731 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT01243307 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT01610011 — Predictive Biomarker (PRD): GLDC mRNA
Genes: GLDC; GCSP
Study NCT00604864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03392025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00056355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02934022 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02755428 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT00730561 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00617032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02376582 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01841281 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01633814 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01520896 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT03790228 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03790228 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03790228 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT01722149 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT04488432 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01765179 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00199706 — Surrogate Endpoint (SUR): Serum sodium
Study NCT00555490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04134676 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04308525 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT03397849 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04233593 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT01231516 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT01677351 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04003168 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT00897351 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00897351 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04649736 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00558142 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04261582 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00108212 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01980654 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00186862 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02732054 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03077360 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04179331 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT04074785 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT04074785 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03520933 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02820337 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study NCT02839954 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT02077179 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03339323 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04507061 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00610597 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00610597 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT02036216 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04404426 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT01137474 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01137474 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03182374 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03651986 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03087448 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03087448 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study NCT00446381 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00446381 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00858312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02492035 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00447980 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study NCT04052204 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT03540654 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03540654 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7