TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00720304 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00573430 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01918007 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01505621 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01755442 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01755442 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00741416 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study NCT04322773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04322773 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04322773 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study NCT04322773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04029974 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00520481 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00102141 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01970696 — Predictive Biomarker (PRD): DICER1 mRNA
Genes: DICER1; DICER; HERNA; KIAA0928
Study NCT00595998 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00074997 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04046848 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02163616 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00876187 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04437875 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03525678 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT03724487 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01243502 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02416531 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02416531 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02416531 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT00528203 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03745612 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02115373 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04824560 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04024852 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05063318 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04599933 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01256788 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03890627 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03422315 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT03258385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04130594 — Surrogate Endpoint (SUR): Neutralizing antibody response
Study NCT04130594 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00696072 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00696072 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03321695 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03321695 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03321695 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02384239 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02384239 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01033175 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study NCT04799834 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04116359 — Predictive Biomarker (PRD): BRD4 mRNA
Genes: BRD4; HUNK1
Study NCT00730067 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00967746 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT02851615 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03629535 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04390100 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT04390100 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04003467 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03056092 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01942837 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03843034 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study NCT03843034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02521532 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01848236 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00745680 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01238172 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT03357575 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00464646 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00192309 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study NCT02501291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03088280 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study NCT03038100 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02138630 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02138630 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01261702 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00872651 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01705171 — Predictive Biomarker (PRD): SLC2A5 mRNA
Genes: SLC2A5; GLUT5
Study NCT04317287 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03350685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04008810 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04008810 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00747851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01455688 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04186429 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04186429 — Safety Biomarker (SAF): BDNF
Study NCT04051164 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03187990 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00140738 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00935480 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT00949546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03956901 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00267137 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02970890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04189068 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04785131 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01023971 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03734796 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT04135274 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT00542269 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03546894 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02926053 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05518097 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT02796170 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02796170 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study NCT02796170 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01753232 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03864107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00732758 — Surrogate Endpoint (SUR): Serum calcium
Study NCT03540303 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00402948 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study NCT00402948 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00947336 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03906292 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03906292 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03514628 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02133599 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02152852 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04414800 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01553981 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01553981 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01208714 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01394796 — Predictive Biomarker (PRD): DYRK1A mRNA
Genes: DYRK1A; DYRK; MNB; MNBH
Study NCT01424384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT04237805 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04237805 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT00926770 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04481191 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03497624 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT03125395 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03909789 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01875653 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04564287 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04018937 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01885767 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01885767 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT00389610 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00214370 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01499940 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02289950 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT03198052 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT03198052 — Predictive Biomarker (PRD): GUCY2C mRNA
Genes: GUCY2C; GUC2C; STAR
Study NCT03198052 — Predictive Biomarker (PRD): PSCA mRNA
Genes: PSCA; UNQ206/PRO232
Study NCT03198052 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03198052 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT03198052 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03198052 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT03198052 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01352715 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT02481674 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03850756 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00813670 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study NCT03951675 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03944577 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03944577 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02830646 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT00342797 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study NCT02420821 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03919526 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03919526 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03224429 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01941836 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00106912 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT01186744 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT02434848 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02911844 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00664833 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT03711578 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT06276829 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT04025853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03524859 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study NCT04575389 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03718286 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03718286 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03708432 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03708432 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03708432 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00936208 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03490331 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study NCT02651675 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study NCT02651675 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01605526 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT03332602 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02875431 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT02372474 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03656289 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT01477853 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01981343 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03729674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01705600 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT01705600 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT00387504 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT00921375 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02168205 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT00783783 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02275039 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00928408 — Surrogate Endpoint (SUR): Serum calcium
Study NCT04594590 — Predictive Biomarker (PRD): SLC25A46 mRNA
Genes: SLC25A46; TB1
Study NCT03171220 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01761292 — Predictive Biomarker (PRD): LTBP4 mRNA
Genes: LTBP4
Study NCT00379652 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01323413 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00174187 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00063765 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study NCT04489173 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02236520 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03173248 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT04077099 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02023463 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00580814 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT02081534 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03834961 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT04454853 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02124382 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT00939874 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00330174 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01734213 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00323440 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study NCT01896869 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00940082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00940082 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00940082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01928355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00633295 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00633295 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT03080766 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT03888664 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT03888664 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03694444 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT01677533 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03914807 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03914807 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT03914807 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03914807 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03914807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01486927 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT04075721 — Predictive Biomarker (PRD): PSMB8 mRNA
Genes: PSMB8; LMP7; PSMB5i; RING10; Y2
Study NCT03939689 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03384615 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT02714816 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT02636582 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01289756 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01289756 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01968200 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01367028 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01084655 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT01529970 — Predictive Biomarker (PRD): PRKN mRNA
Genes: PRKN; PARK2
Study NCT01529970 — Predictive Biomarker (PRD): PINK1 mRNA
Genes: PINK1
Study NCT01529970 — Predictive Biomarker (PRD): ATP13A2 mRNA
Genes: ATP13A2; PARK9
Study NCT01140451 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03959891 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03959891 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03606369 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT02887677 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00071890 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00071890 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00330434 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT00668213 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02655120 — Predictive Biomarker (PRD): BMP7 mRNA
Genes: BMP7; OP1
Study NCT04683250 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT00923390 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT00923390 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study NCT05089968 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02792088 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01152957 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03659448 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04457297 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study NCT04457297 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00014859 — Predictive Biomarker (PRD): SFTPB mRNA
Genes: SFTPB; SFTP3
Study NCT02698267 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03406611 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT02854514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02604940 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01816035 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01816035 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04824300 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00711984 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00819273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01723878 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1