TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25118980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18801760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15105384 — Safety Biomarker (SAF): Hyaluronic acid
Study 20818862 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20818862 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11078282 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11078282 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31662515 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 31662515 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31662515 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29895587 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29895587 — Surrogate Endpoint (SUR): Blood pressure
Study 25282317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25282317 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19449118 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 19449118 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 19449118 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15721570 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 12049621 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 12049621 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10439495 — Surrogate Endpoint (SUR): Blood pressure
Study 2105625 — Surrogate Endpoint (SUR): Blood pressure
Study 26744141 — Surrogate Endpoint (SUR): Bone mineral density
Study 19826288 — Surrogate Endpoint (SUR): Blood pressure
Study 24836125 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24836125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22733440 — Surrogate Endpoint (SUR): Bone mineral density
Study 18230966 — Surrogate Endpoint (SUR): Blood pressure
Study 3563121 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29701042 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29701042 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27316324 — Surrogate Endpoint (SUR): Blood pressure
Study 23931043 — Surrogate Endpoint (SUR): Blood pressure
Study 23931043 — Surrogate Endpoint (SUR): Serum calcium
Study 20099160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14983963 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23254592 — Surrogate Endpoint (SUR): Blood pressure
Study 23254592 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23254592 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21364610 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7334934 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31503258 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 25040143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17875948 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17875948 — Surrogate Endpoint (SUR): Blood pressure
Study 11297574 — Surrogate Endpoint (SUR): Bone mineral density
Study 11297574 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11297574 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9208491 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 1443204 — Surrogate Endpoint (SUR): Blood pressure
Study 30714486 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 28724185 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16873344 — Surrogate Endpoint (SUR): Blood pressure
Study 10193813 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10193813 — Surrogate Endpoint (SUR): Blood pressure
Study 7053160 — Surrogate Endpoint (SUR): Blood pressure
Study 18534087 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12885990 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 11789186 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11526545 — Monitoring Biomarker (MOI): HBV DNA
Study 27433861 — Surrogate Endpoint (SUR): Blood pressure
Study 22990352 — Surrogate Endpoint (SUR): Blood pressure
Study 12548129 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7720762 — Surrogate Endpoint (SUR): Blood pressure
Study 30817251 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30817251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24282136 — Surrogate Endpoint (SUR): Blood pressure
Study 20515580 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18831357 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2128415 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31690303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31690303 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25313573 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18046108 — Surrogate Endpoint (SUR): Blood pressure
Study 10090337 — Surrogate Endpoint (SUR): Blood pressure
Study 10090337 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1969115 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28324265 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23742877 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14615734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14615734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30412061 — Surrogate Endpoint (SUR): Blood pressure
Study 25686644 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 11061474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22965622 — Surrogate Endpoint (SUR): Blood pressure
Study 1559504 — Surrogate Endpoint (SUR): Blood pressure
Study 18398944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18398944 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9759992 — Surrogate Endpoint (SUR): Blood pressure
Study 27223846 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20506355 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11048472 — Surrogate Endpoint (SUR): Blood pressure
Study 29324186 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 22574589 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 22574589 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22574589 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22574589 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 22574589 — Surrogate Endpoint (SUR): Serum creatinine
Study 10323426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21975348 — Predictive Biomarker (PRD): GPR119 mRNA
Genes: GPR119
Study 21975348 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21975348 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 6319452 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18336635 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16861420 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 16861420 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 12874612 — Surrogate Endpoint (SUR): Blood pressure
Study 22560357 — Predictive Biomarker (PRD): NR4A3 mRNA
Genes: NR4A3; CHN; CSMF; MINOR; NOR1; TEC
Study 31013182 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 20596692 — Surrogate Endpoint (SUR): Blood pressure
Study 20596692 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7752328 — Surrogate Endpoint (SUR): Blood pressure
Study 17255299 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9713297 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27480340 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27480340 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9442424 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7954041 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7954041 — Surrogate Endpoint (SUR): Blood pressure
Study 22342928 — Safety Biomarker (SAF): Hyaluronic acid
Study 20213795 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15932816 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 11464953 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 11464953 — Safety Biomarker (SAF): BDNF
Study 3533566 — Surrogate Endpoint (SUR): Blood pressure
Study 24669646 — Surrogate Endpoint (SUR): Blood pressure
Study 12816171 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8788540 — Surrogate Endpoint (SUR): Blood pressure
Study 29183775 — Surrogate Endpoint (SUR): Serum calcium
Study 23412304 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 23216922 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 23029966 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8774269 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8774269 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1377412 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1377412 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1377412 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28734553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28734553 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 28734553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27304196 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17507912 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 16914459 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 14597936 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14597936 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8737752 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8737752 — Surrogate Endpoint (SUR): Blood pressure
Study 28489759 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 26042031 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 26042031 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 20530276 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16633890 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16633890 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30905652 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30905652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30905652 — Safety Biomarker (SAF): Interleukin 1
Study 30905652 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15209626 — Monitoring Biomarker (MOI): HBV DNA
Study 7943596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7943596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3285170 — Surrogate Endpoint (SUR): Serum potassium
Study 3285170 — Surrogate Endpoint (SUR): Serum calcium
Study 25416602 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 22592214 — Surrogate Endpoint (SUR): Blood pressure
Study 19878508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17367313 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 8751336 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 6944708 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 28412009 — Surrogate Endpoint (SUR): Blood pressure
Study 9848776 — Surrogate Endpoint (SUR): Blood pressure
Study 9848776 — Surrogate Endpoint (SUR): Serum creatinine
Study 31855498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28416405 — Surrogate Endpoint (SUR): Blood pressure
Study 21554040 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21554040 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 14515185 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 14515185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9032177 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9032177 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 9032177 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 22513296 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 22513296 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22513296 — Predictive Biomarker (PRD): INSIG2 mRNA
Genes: INSIG2
Study 22513296 — Predictive Biomarker (PRD): TNNI3K mRNA
Genes: TNNI3K; CARK
Study 22513296 — Predictive Biomarker (PRD): NISCH mRNA
Genes: NISCH; IRAS; KIAA0975
Study 22513296 — Predictive Biomarker (PRD): STAB1 mRNA
Genes: STAB1; FEEL1; KIAA0246
Study 22513296 — Predictive Biomarker (PRD): MTIF3 mRNA
Genes: MTIF3; DC38
Study 22513296 — Predictive Biomarker (PRD): QPCTL mRNA
Genes: QPCTL
Study 22513296 — Predictive Biomarker (PRD): GIPR mRNA
Genes: GIPR
Study 22513296 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 8973975 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29428751 — Surrogate Endpoint (SUR): Blood pressure
Study 29428751 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27724870 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24417206 — Predictive Biomarker (PRD): SCN1A mRNA
Genes: SCN1A; NAC1; SCN1
Study 22833186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29231523 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12839693 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 24062397 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 22182951 — Surrogate Endpoint (SUR): Blood pressure
Study 9604053 — Surrogate Endpoint (SUR): Bone mineral density
Study 31906766 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 29563779 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29563779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29563779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29563779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26876716 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 11230840 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8565032 — Surrogate Endpoint (SUR): Blood pressure
Study 25851635 — Surrogate Endpoint (SUR): Serum calcium
Study 25851635 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 12716329 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 30511958 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24169284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8716209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3061032 — Surrogate Endpoint (SUR): Blood pressure
Study 10744189 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10438706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2222952 — Surrogate Endpoint (SUR): Blood pressure
Study 21327796 — Surrogate Endpoint (SUR): Blood pressure
Study 8430676 — Surrogate Endpoint (SUR): Serum creatinine
Study 8430676 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29362444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20721920 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 19026251 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 12663706 — Predictive Biomarker (PRD): ZBTB7A mRNA
Genes: ZBTB7A; FBI1; LRF; ZBTB7; ZNF857A
Study 9370178 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9370178 — Surrogate Endpoint (SUR): Serum creatinine
Study 20587720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20587720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20587720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20587720 — Surrogate Endpoint (SUR): Blood pressure
Study 10362181 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 1897264 — Surrogate Endpoint (SUR): Blood pressure
Study 6275999 — Surrogate Endpoint (SUR): Serum creatinine
Study 15447735 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15447735 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 2732065 — Surrogate Endpoint (SUR): Blood pressure
Study 1103617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27376875 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27376875 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 27376875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26203826 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 26203826 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19187638 — Predictive Biomarker (PRD): NTRK3 mRNA
Genes: NTRK3; TRKC
Study 19187638 — Predictive Biomarker (PRD): NTRK
Study 28796990 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28796990 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 28796990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18573712 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 19957796 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 19957796 — Predictive Biomarker (PRD): NGFR mRNA
Genes: NGFR; TNFRSF16
Study 17426704 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17426704 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 17426704 — Predictive Biomarker (PRD): Microsatellite instability
Study 15821379 — Surrogate Endpoint (SUR): Blood pressure
Study 9778225 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 29871978 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29871978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16721698 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 8390529 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31440954 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 10509765 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1768163 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 15292480 — Surrogate Endpoint (SUR): Blood pressure
Study 16972100 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 12594647 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15294013 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11878725 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9628276 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study 28464042 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 23760288 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 23760288 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16487437 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 14530608 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24427694 — Surrogate Endpoint (SUR): Blood pressure
Study 26691409 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 25178924 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 17305413 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 10223780 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8665994 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21289263 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 21289263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2