TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02215876 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02215876 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02362620 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT02362620 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02362620 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00409682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00071942 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT01422122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00052351 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00052351 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01785472 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01206946 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study NCT02405169 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT03121664 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00411359 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01483781 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01964391 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03553251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00150826 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00150826 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00533689 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00058786 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT00058786 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01118624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00946556 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02386436 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study NCT04146194 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00929175 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02625441 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03474640 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03800836 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01373203 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT01373203 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT01373203 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study NCT03960775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01449461 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01449461 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03666312 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT03666312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03203265 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05384184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05384184 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT05384184 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study NCT02613650 — Predictive Biomarker (PRD): HRAS mRNA
Genes: HRAS; HRAS1
Study NCT02613650 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT02613650 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04509596 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02744664 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00809666 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04056572 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01539551 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02686086 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04576598 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00568516 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00957528 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03755934 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04292808 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03361800 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03361800 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01523496 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT00823628 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04160455 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03590691 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02146508 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study NCT04524949 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study NCT02456844 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02456844 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02456844 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT01439321 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT03144245 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT02970604 — Predictive Biomarker (PRD): CNTN4 mRNA
Genes: CNTN4
Study NCT04066270 — Predictive Biomarker (PRD): COCH mRNA
Genes: COCH; COCH5B2; UNQ257/PRO294
Study NCT01278745 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study NCT02167698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02371226 — Predictive Biomarker (PRD): IDUA mRNA
Genes: IDUA
Study NCT03914794 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT03574675 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00496730 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00800436 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04142931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01753245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02096796 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03123120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02583906 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04477694 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01535170 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study NCT00006394 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02813785 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01610284 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01610284 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01610284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01610284 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01610284 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01668784 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03506035 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study NCT00202787 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00202787 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT04132102 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03779009 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT03568591 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03666819 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02125734 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT03425773 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03641872 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01849068 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study NCT01849068 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01849068 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study NCT01849068 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01028638 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01396499 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00878969 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02447315 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study NCT05421936 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06369792 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT04546321 — Surrogate Endpoint (SUR): Serum sodium
Study NCT04546321 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02213562 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT01451879 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT04424654 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04424654 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00595322 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04104490 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04104490 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04187638 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT03645824 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT01305889 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01305889 — Safety Biomarker (SAF): BDNF
Study NCT00524342 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00524342 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study NCT00524342 — Predictive Biomarker (PRD): VWF mRNA
Genes: VWF; F8VWF
Study NCT04334824 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03043001 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03620201 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study NCT03620201 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03744962 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT00247845 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01402297 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01783600 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03166540 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01312233 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT03503201 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT03503201 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT03503201 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03503201 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01766141 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT02756169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03671564 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT01265875 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT01033513 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03630211 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03442673 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04001621 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04001621 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01840579 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02216721 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT02216721 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02794701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00847782 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01185509 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01074970 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00523159 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02247635 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03780803 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01381302 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT00923130 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04206436 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04206436 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02601612 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04632758 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02242331 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01651715 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study NCT00217204 — Surrogate Endpoint (SUR): Fecal coefficient of fat absorption
Study NCT04224675 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04264403 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04421820 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study NCT03587220 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT01660360 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01217671 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT02071862 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT02071862 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT02071862 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT02071862 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02071862 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study NCT02072408 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01088776 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03870984 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT03870984 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03683121 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00634634 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00440908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01202370 — Pharmacodynamic Biomarker (PDY): DNA topoisomerase I
Genes: TOP1
Study NCT01601327 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study NCT04259450 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04259450 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study NCT01619644 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT01619644 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT01952119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00514514 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00472433 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT00472433 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02288936 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT01567709 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT02066688 — Surrogate Endpoint (SUR): Serum calcium
Study NCT03603860 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00224458 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01021956 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01021956 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01300338 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03066128 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00880399 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01922817 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03889925 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04420000 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03943407 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT03943407 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study NCT03943407 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study NCT00111800 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00084318 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03260504 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03719690 — Predictive Biomarker (PRD): HRAS mRNA
Genes: HRAS; HRAS1
Study NCT04220021 — Pharmacodynamic Biomarker (PDY): Guanine nucleotide exchange factor C9orf72
Genes: C9orf72; DENND9; DENNL72
Study NCT04220021 — Predictive Biomarker (PRD): C9 mRNA
Genes: C9
Study NCT00622674 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03185364 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00928889 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00928889 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02317861 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02921620 — Predictive Biomarker (PRD): PRX mRNA
Genes: PRX; KIAA1620
Study NCT03149068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03149068 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT03789851 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03085797 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT05435703 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04174417 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04566770 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04166253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03837639 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03837639 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00625469 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00864643 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00864643 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02624037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03727477 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03727477 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study NCT03727477 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT03688503 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03902431 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00113828 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT01643629 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT00400673 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04137692 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study NCT04700839 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT01484548 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study NCT02282592 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03034564 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02965391 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02883712 — Predictive Biomarker (PRD): SLC35A2 mRNA
Genes: SLC35A2; UGALT; UGT; UGTL
Study NCT02883712 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study NCT02883712 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT04247633 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03432676 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT00027534 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01590550 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01951443 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04538521 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT02258451 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02258451 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02258451 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02864368 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00445419 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04186494 — Surrogate Endpoint (SUR): Blood pressure