TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7608310 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7608310 — Surrogate Endpoint (SUR): Blood pressure
Study 2092880 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20725124 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 20725124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20725124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28573765 — Surrogate Endpoint (SUR): Blood pressure
Study 23401397 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23401397 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 23401397 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15143718 — Surrogate Endpoint (SUR): Serum sodium
Study 11448297 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31654725 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31654725 — Surrogate Endpoint (SUR): Blood pressure
Study 21247484 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 17717313 — Predictive Biomarker (PRD): ACSL1 mRNA
Genes: ACSL1; FACL1; FACL2; LACS; LACS1; LACS2
Study 7402084 — Surrogate Endpoint (SUR): Blood pressure
Study 31583253 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31583253 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15042607 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11303306 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 11303306 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 27581533 — Surrogate Endpoint (SUR): Blood pressure
Study 26130347 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 20385970 — Surrogate Endpoint (SUR): Blood pressure
Study 8574252 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8574252 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31036625 — Surrogate Endpoint (SUR): Bone mineral density
Study 27402913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27402913 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 21836105 — Surrogate Endpoint (SUR): Blood pressure
Study 21836105 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31953524 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 31953524 — Predictive Biomarker (PRD): Leucine-rich alpha-2-glycoprotein
Genes: LRG1; LRG
Study 9352699 — Surrogate Endpoint (SUR): Blood pressure
Study 3767015 — Surrogate Endpoint (SUR): Blood pressure
Study 8901787 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 1859009 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17459695 — Surrogate Endpoint (SUR): Blood pressure
Study 16089136 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 28784510 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 28784510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28784510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28784510 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8819128 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8819128 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24589725 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20041960 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 15661451 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 25409100 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 9892499 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 9892499 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15034704 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27143594 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27143594 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20370938 — Surrogate Endpoint (SUR): Bone mineral density
Study 2223340 — Predictive Biomarker (PRD): ACHE mRNA
Genes: ACHE
Study 30205115 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 30205115 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 30205115 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 8680689 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8680689 — Surrogate Endpoint (SUR): Blood pressure
Study 28373993 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15692755 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15692755 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 15692755 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27385022 — Surrogate Endpoint (SUR): Serum creatinine
Study 15194017 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3661107 — Surrogate Endpoint (SUR): Blood pressure
Study 28728886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19930764 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 19930764 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 14696461 — Monitoring Biomarker (MOI): HBV DNA
Study 17680827 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 23210916 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2948826 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 3154686 — Surrogate Endpoint (SUR): Blood pressure
Study 30877209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30877209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29142236 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-210
Genes: MIR210
Study 29142236 — Safety Biomarker (SAF): miR-22
Genes: MIR22
Study 25441251 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25441251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25441251 — Surrogate Endpoint (SUR): Blood pressure
Study 21699432 — Surrogate Endpoint (SUR): Blood pressure
Study 18504236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16426961 — Surrogate Endpoint (SUR): Bone mineral density
Study 11153621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29945555 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study 27006113 — Safety Biomarker (SAF): DRD2
Study 9759984 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9759984 — Surrogate Endpoint (SUR): Blood pressure
Study 15042325 — Safety Biomarker (SAF): DRD2
Study 2720864 — Surrogate Endpoint (SUR): Blood pressure
Study 24274771 — Surrogate Endpoint (SUR): Blood pressure
Study 22170713 — Predictive Biomarker (PRD): GATA4 mRNA
Genes: GATA4
Study 22170713 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 20691307 — Surrogate Endpoint (SUR): Blood pressure
Study 12417288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10520779 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 10520779 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 10520779 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 10520779 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10520779 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24195291 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21602648 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8448066 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3298412 — Monitoring Biomarker (MOI): HBV DNA
Study 30237705 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 26565005 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 19861267 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19861267 — Surrogate Endpoint (SUR): Blood pressure
Study 15733401 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 24574227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18854748 — Surrogate Endpoint (SUR): Blood pressure
Study 16097419 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 16097419 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 11791086 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10604491 — Surrogate Endpoint (SUR): Blood pressure
Study 7781871 — Surrogate Endpoint (SUR): Bone mineral density
Study 7781871 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30912690 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 18372684 — Surrogate Endpoint (SUR): Blood pressure
Study 7617869 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 15820533 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23225299 — Surrogate Endpoint (SUR): Bone mineral density
Study 10710122 — Surrogate Endpoint (SUR): Blood pressure
Study 9015796 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 29989185 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 28089902 — Surrogate Endpoint (SUR): Blood pressure
Study 18339052 — Surrogate Endpoint (SUR): Bone mineral density
Study 31722337 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28641925 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study 8744700 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8744700 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31347165 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31347165 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31347165 — Safety Biomarker (SAF): Interleukin 1
Study 26463012 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 17264174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14704540 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 11474327 — Surrogate Endpoint (SUR): Blood pressure
Study 2927302 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28576675 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28576675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28576675 — Predictive Biomarker (PRD): Hormone receptor
Study 23859389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23859389 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 23859389 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23859389 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22585697 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 10400422 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 7549366 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31330899 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25958709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25432081 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 25432081 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19468030 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16760197 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 31425478 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26396095 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 26396095 — Surrogate Endpoint (SUR): Bone mineral density
Study 21237502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16202482 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11688554 — Surrogate Endpoint (SUR): Blood pressure
Study 21501093 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 21501093 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 26105600 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21946486 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19339531 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 10785873 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7802571 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17616470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27107672 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27107672 — Safety Biomarker (SAF): BDNF
Study 24784698 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9810148 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9810148 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 31310990 — Surrogate Endpoint (SUR): Blood pressure
Study 22022584 — Surrogate Endpoint (SUR): Bone mineral density
Study 29888581 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28622156 — Surrogate Endpoint (SUR): Blood pressure
Study 1798003 — Surrogate Endpoint (SUR): Blood pressure
Study 7039160 — Predictive Biomarker (PRD): LORICRIN mRNA
Genes: LORICRIN; LOR; LRN
Study 25288340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21764858 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21764858 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25142571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22952383 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28886209 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 23841532 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 16000127 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8596268 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 26643404 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24038797 — Surrogate Endpoint (SUR): Blood pressure
Study 21910701 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 21180008 — Safety Biomarker (SAF): PPOX
Genes: HCRT; OX
Study 9814468 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 23505005 — Predictive Biomarker (PRD): CA3 mRNA
Genes: CA3
Study 16859143 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16859143 — Surrogate Endpoint (SUR): Blood pressure
Study 11471481 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18476982 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26511535 — Surrogate Endpoint (SUR): Blood pressure
Study 22854412 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22854412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21726411 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 19562990 — Monitoring Biomarker (MOI): Procalcitonin
Study 21075773 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10911769 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 18657672 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11109976 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11109976 — Surrogate Endpoint (SUR): Bone mineral density
Study 23044231 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23044231 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 20392866 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 18263770 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10561192 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10561192 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7657848 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7657848 — Surrogate Endpoint (SUR): Blood pressure
Study 2750531 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 28846009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28846009 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26324672 — Surrogate Endpoint (SUR): Blood pressure
Study 25168268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22361261 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22361261 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 16288342 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21980828 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 21980828 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 1827967 — Surrogate Endpoint (SUR): Blood pressure
Study 7034617 — Surrogate Endpoint (SUR): Blood pressure
Study 22823871 — Surrogate Endpoint (SUR): Blood pressure
Study 17592102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17592102 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 16096436 — Predictive Biomarker (PRD): BMF mRNA
Genes: BMF
Study 31912603 — Surrogate Endpoint (SUR): Blood pressure
Study 20877298 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 20877298 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 20877298 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9835755 — Surrogate Endpoint (SUR): Blood pressure
Study 7721404 — Surrogate Endpoint (SUR): Blood pressure
Study 25329583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25329583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15134985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12420197 — Surrogate Endpoint (SUR): Blood pressure
Study 17523399 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15342615 — Surrogate Endpoint (SUR): Blood pressure
Study 11532109 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11532109 — Surrogate Endpoint (SUR): Serum creatinine
Study 11532109 — Surrogate Endpoint (SUR): Blood pressure
Study 31387559 — Monitoring Biomarker (MOI): Procalcitonin
Study 23291105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25303950 — Predictive Biomarker (PRD): HOXA10 mRNA
Genes: HOXA10; HOX1H
Study 18983928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18983928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1971170 — Surrogate Endpoint (SUR): Blood pressure
Study 33376 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22281412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10450120 — Surrogate Endpoint (SUR): Blood pressure
Study 7503082 — Surrogate Endpoint (SUR): Blood pressure
Study 25261291 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 19238124 — Safety Biomarker (SAF): DRD2
Study 15022801 — Surrogate Endpoint (SUR): Bone mineral density
Study 18207280 — Monitoring Biomarker (MOI): HBV DNA
Study 31669136 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30545134 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 7860310 — Safety Biomarker (SAF): Hypoxanthine-guanine phosphoribosyltransferase
Genes: HPRT1; HPRT
Study 31056655 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31056655 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28418028 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 27238963 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 17696825 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14517164 — Surrogate Endpoint (SUR): Blood pressure
Study 10996360 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 10996360 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 2671402 — Surrogate Endpoint (SUR): Serum creatinine
Study 618025 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31796986 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27079636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27079636 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25727879 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8020904 — Surrogate Endpoint (SUR): Plasma ammonia
Study 30366945 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS