TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11560127 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11560127 — Surrogate Endpoint (SUR): Blood pressure
Study 2662897 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8490316 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27185372 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 27185372 — Predictive Biomarker (PRD): FOXA1 mRNA
Genes: FOXA1; HNF3A; TCF3A
Study 27185372 — Predictive Biomarker (PRD): TFAP2C mRNA
Genes: TFAP2C
Study 27185372 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22302780 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 20536646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20536646 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 20536646 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 31838462 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30678759 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25132248 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21840467 — Safety Biomarker (SAF): Reactive oxygen species
Study 21840467 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11736674 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 9434921 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9434921 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14570681 — Surrogate Endpoint (SUR): Blood pressure
Study 2865021 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26106623 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20878571 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20878571 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20878571 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 20878571 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20878571 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27013060 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 27013060 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 18381948 — Predictive Biomarker (PRD): Hormone receptor
Study 31042578 — Predictive Biomarker (PRD): PLN mRNA
Genes: PLN; PLB
Study 19352247 — Surrogate Endpoint (SUR): Blood pressure
Study 17584671 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 7915853 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 7687093 — Surrogate Endpoint (SUR): Blood pressure
Study 22643213 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19220275 — Safety Biomarker (SAF): DRD3
Study 24032193 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 4907811 — Surrogate Endpoint (SUR): Blood pressure
Study 17303710 — Safety Biomarker (SAF): Reactive oxygen species
Study 15108068 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9892907 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28405623 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 28405623 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28405623 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 28405623 — Predictive Biomarker (PRD): CIITA mRNA
Genes: CIITA; MHC2TA
Study 28405623 — Predictive Biomarker (PRD): IL12RB1 mRNA
Genes: IL12RB1; IL12R; IL12RB
Study 16293363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2163421 — Surrogate Endpoint (SUR): Blood pressure
Study 21593355 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 3948546 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28295425 — Surrogate Endpoint (SUR): Blood pressure
Study 16522922 — Surrogate Endpoint (SUR): Bone mineral density
Study 8067760 — Surrogate Endpoint (SUR): Serum uric acid
Study 3056132 — Surrogate Endpoint (SUR): Blood pressure
Study 23445135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16364599 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 16364599 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study 16551310 — Surrogate Endpoint (SUR): Blood pressure
Study 1294055 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29471904 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27166229 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 20142635 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10567627 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8881455 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 1810019 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 6835734 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31250540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31250540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17825130 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 9141939 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 23471131 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17404783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2834938 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2834938 — Surrogate Endpoint (SUR): Blood pressure
Study 19195513 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19195513 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15309292 — Predictive Biomarker (PRD): ADRA2B mRNA
Genes: ADRA2B; ADRA2L1; ADRA2RL1
Study 26932733 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17667145 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17667145 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17667145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17667145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15833887 — Surrogate Endpoint (SUR): Blood pressure
Study 11981357 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11981357 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 11981357 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 8918498 — Predictive Biomarker (PRD): Hormone receptor
Study 3304725 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24878174 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 20175241 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20175241 — Surrogate Endpoint (SUR): Blood pressure
Study 17272962 — Surrogate Endpoint (SUR): Blood pressure
Study 17272962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7843751 — Surrogate Endpoint (SUR): Blood pressure
Study 26315981 — Surrogate Endpoint (SUR): Blood pressure
Study 19429471 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15158344 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 15158344 — Predictive Biomarker (PRD): Liver iron
Study 9278211 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 9278211 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9278211 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 3495027 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 22951500 — Surrogate Endpoint (SUR): Bone mineral density
Study 11130773 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7957160 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24694794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21054850 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15947724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 10686834 — Predictive Biomarker (PRD): TP53INP1 mRNA
Genes: TP53INP1; P53DINP1; SIP
Study 8850174 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1928808 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1928808 — Surrogate Endpoint (SUR): Blood pressure
Study 1928808 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1928808 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29063307 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 29786356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29786356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29786356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15691303 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12609711 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 1683217 — Surrogate Endpoint (SUR): Blood pressure
Study 25577201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25577201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16313112 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10588093 — Surrogate Endpoint (SUR): Blood pressure
Study 30367320 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26561301 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 19054024 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 15136504 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 15136504 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29570475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26272328 — Surrogate Endpoint (SUR): Blood pressure
Study 23299763 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18241359 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 18241359 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 12639160 — Surrogate Endpoint (SUR): Blood pressure
Study 19686437 — Safety Biomarker (SAF): Hyaluronic acid
Study 10526909 — Surrogate Endpoint (SUR): Blood pressure
Study 12373040 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 7247587 — Surrogate Endpoint (SUR): Blood pressure
Study 22948036 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 4068909 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22940436 — Predictive Biomarker (PRD): TMEM11 mRNA
Genes: TMEM11; C17orf35; PM1
Study 12691375 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8923833 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8923833 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8923833 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27627192 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24393349 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24393349 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20339359 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 20339359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12358231 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30045259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30045259 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 23024015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20673353 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18486740 — Safety Biomarker (SAF): Interleukin 12
Study 25826885 — Predictive Biomarker (PRD): ATF7 mRNA
Genes: ATF7; ATFA
Study 12136395 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12136395 — Surrogate Endpoint (SUR): Blood pressure
Study 489201 — Surrogate Endpoint (SUR): Blood pressure
Study 28317287 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28317287 — Safety Biomarker (SAF): BDNF
Study 24739801 — Surrogate Endpoint (SUR): Blood pressure
Study 21221987 — Surrogate Endpoint (SUR): Blood pressure
Study 19961455 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9655746 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 335516 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 27709313 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27709313 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 25133860 — Surrogate Endpoint (SUR): Blood pressure
Study 19114862 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8707075 — Surrogate Endpoint (SUR): Blood pressure
Study 14693730 — Surrogate Endpoint (SUR): Serum testosterone
Study 29729427 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 24160850 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 24160850 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study 24160850 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9793253 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19427180 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16864724 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12934420 — Surrogate Endpoint (SUR): Blood pressure
Study 7949548 — Surrogate Endpoint (SUR): Serum creatinine
Study 3668883 — Surrogate Endpoint (SUR): Blood pressure
Study 15269990 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27030575 — Predictive Biomarker (PRD): TSTD1 mRNA
Genes: TSTD1; KAT
Study 12521974 — Surrogate Endpoint (SUR): Blood pressure
Study 22689695 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30696336 — Surrogate Endpoint (SUR): Bone mineral density
Study 29261439 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29261439 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 29261439 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 29261439 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 24777114 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12082591 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 28614793 — Surrogate Endpoint (SUR): Blood pressure
Study 19517101 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 9762777 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31676670 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 16990155 — Surrogate Endpoint (SUR): Blood pressure
Study 12212248 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 3932470 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 27062041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27062041 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22812731 — Surrogate Endpoint (SUR): Blood pressure
Study 17585003 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7992988 — Surrogate Endpoint (SUR): Blood pressure
Study 7992988 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30655568 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30655568 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 30655568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30655568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28407735 — Monitoring Biomarker (MOI): HBV DNA
Study 9665109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 361988 — Surrogate Endpoint (SUR): Blood pressure
Study 24647318 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8110435 — Surrogate Endpoint (SUR): Blood pressure
Study 2944688 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 27678295 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19940012 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18981327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18981327 — Surrogate Endpoint (SUR): Blood pressure
Study 10622084 — Surrogate Endpoint (SUR): Bone mineral density
Study 8075589 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8075589 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 8075589 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 8075589 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 23242004 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 23242004 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17080254 — Safety Biomarker (SAF): L-acetylcarnitine
Study 31170412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25421542 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25421542 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14732882 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1599343 — Surrogate Endpoint (SUR): Blood pressure
Study 30723140 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30723140 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30723140 — Predictive Biomarker (PRD): Hormone receptor
Study 30723140 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 22623022 — Surrogate Endpoint (SUR): Blood pressure
Study 19389019 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 2947874 — Surrogate Endpoint (SUR): Blood pressure
Study 26105554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24769306 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24769306 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24769306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21397720 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21397720 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21397720 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11261274 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 6282024 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 6282024 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 6282024 — Surrogate Endpoint (SUR): Blood pressure
Study 19444142 — Surrogate Endpoint (SUR): Blood pressure
Study 17464949 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8730122 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8730122 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8730122 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25545309 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 12528101 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27864694 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17575470 — Surrogate Endpoint (SUR): Blood pressure
Study 7911266 — Predictive Biomarker (PRD): IFT122 mRNA
Genes: IFT122; SPG; WDR10; WDR140
Study 26358375 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 25547339 — Surrogate Endpoint (SUR): Blood pressure
Study 23797811 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 3354444 — Surrogate Endpoint (SUR): Blood pressure
Study 21740570 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 7980764 — Surrogate Endpoint (SUR): Blood pressure
Study 25163498 — Surrogate Endpoint (SUR): Blood pressure
Study 25163498 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25163498 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30919377 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 23390999 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11179530 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1884902 — Surrogate Endpoint (SUR): Blood pressure
Study 1884902 — Surrogate Endpoint (SUR): Serum potassium
Study 28125095 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 22883004 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 2871486 — Surrogate Endpoint (SUR): Serum creatinine
Study 31145180 — Surrogate Endpoint (SUR): Blood pressure
Study 26600017 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 21611754 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24467642 — Surrogate Endpoint (SUR): Bone mineral density
Study 24467642 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21875783 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 17945069 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26056856 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17767800 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8857512 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 6476299 — Surrogate Endpoint (SUR): Blood pressure