TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02569164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02139579 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02139579 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02139579 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02139579 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT02139579 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02929407 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03418961 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04978103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01418014 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01333631 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02036853 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study NCT03497351 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01309282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04023734 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00504530 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study NCT00908089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03291886 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00725062 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00715988 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00715988 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT00715988 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00715988 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02001753 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03047928 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT03047928 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04470284 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00361777 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT00361777 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02507167 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT02775253 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study NCT01601002 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study NCT03085667 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT00504972 — Predictive Biomarker (PRD): CD74 mRNA
Genes: CD74; DHLAG
Study NCT02035254 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00781885 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03684824 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01641939 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01641939 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02055612 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03128229 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03128229 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT02042872 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04359771 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04359771 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01160939 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04177576 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT01074593 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT03788772 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT03115541 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03536793 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT03536793 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study NCT02513927 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02267876 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00646178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04267913 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study NCT04044170 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04044170 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02862067 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02049541 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04493060 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04493060 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT02505828 — Predictive Biomarker (PRD): DCLRE1C mRNA
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study NCT01492998 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT04416295 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT03476590 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01474954 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT04389944 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01992809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01929148 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02995824 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT01623557 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT03023813 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02521701 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT02634580 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01598129 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04473690 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01082562 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01082562 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00922025 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03916744 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03916744 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03916744 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04324307 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT00139477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04220476 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04220476 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04220476 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02267317 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT02401737 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03383575 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT01669954 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00159432 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00159432 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03453281 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00983983 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT01297491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00000400 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03973060 — Predictive Biomarker (PRD): ACTN3 mRNA
Genes: ACTN3
Study NCT00003897 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01766505 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04095039 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT04095039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01065350 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00388193 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00388193 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00620529 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00004232 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02588742 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04363099 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03342131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01706575 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01737099 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04692636 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04543214 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT02032238 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01394705 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04400474 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04400474 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02995304 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00577993 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01416233 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01933022 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT01407211 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01912209 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02468635 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03894215 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03892278 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01363869 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT01994889 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT01640457 — Predictive Biomarker (PRD): SOX9 mRNA
Genes: SOX9
Study NCT03442374 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT03442374 — Predictive Biomarker (PRD): PAX7 mRNA
Genes: PAX7; HUP1
Study NCT03442374 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study NCT03442374 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study NCT03442374 — Predictive Biomarker (PRD): COL3A1 mRNA
Genes: COL3A1
Study NCT03442374 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study NCT03442374 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study NCT03442374 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study NCT03442374 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study NCT03442374 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03442374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03442374 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study NCT04082260 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT00257439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04036461 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03892447 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT01736059 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04429087 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study NCT01618734 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT00704262 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00704262 — Surrogate Endpoint (SUR): Serum calcium
Study NCT03423199 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03423199 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03423199 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02439489 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02439489 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02439489 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02439489 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00625430 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study NCT02712047 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01925378 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01569256 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01569256 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT01543516 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02972567 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02972567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02366507 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04147351 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01629225 — Predictive Biomarker (PRD): GRK4 mRNA
Genes: GRK4; GPRK2L; GPRK4
Study NCT03418532 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03418532 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03418532 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT03418532 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03418532 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01622309 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02529553 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT02529553 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT02784639 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03211052 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03211052 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT03718780 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02145650 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT01981551 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT01981551 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study NCT03011671 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03231878 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study NCT03231878 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT03253861 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01827423 — Predictive Biomarker (PRD): SERPINB3 mRNA
Genes: SERPINB3; SCCA; SCCA1
Study NCT02174575 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT00539032 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study NCT03515915 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT01043939 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00272896 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT00272896 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03506425 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03132181 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03132181 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00361595 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00006070 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00071968 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02065973 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT05135143 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study NCT05135143 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT02426177 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01067092 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03519529 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT03341169 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT01966237 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01578226 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT04468997 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04521114 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT04291495 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study NCT04291495 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT00621348 — Surrogate Endpoint (SUR): Serum sodium
Study NCT03402464 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03181646 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04610528 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT04610528 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01658657 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01715584 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01715584 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03052478 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH
Study NCT02159300 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study NCT01854372 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT00640224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04199325 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00718653 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01940666 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT03081936 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT03133741 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02824406 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00021918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01533584 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03680326 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03680326 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02644109 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT01820442 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04632355 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT02421341 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00289406 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00642785 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01428401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01428401 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01406613 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00599807 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02972333 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04655651 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT03208582 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02215811 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02571335 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02571335 — Safety Biomarker (SAF): BDNF
Study NCT04176848 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study NCT00391404 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00610662 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01419197 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02479802 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00881881 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study NCT03383952 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01190111 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03309826 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04373798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00803205 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02456350 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02456350 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT01418001 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT01316250 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11