TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20598667 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 16368446 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16368446 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2574051 — Safety Biomarker (SAF): DRD2
Study 31061252 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31061252 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 31061252 — Surrogate Endpoint (SUR): Blood pressure
Study 26314532 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 11138573 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9177418 — Surrogate Endpoint (SUR): Bone mineral density
Study 3429867 — Surrogate Endpoint (SUR): Blood pressure
Study 17003850 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17003850 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 18551027 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18551027 — Surrogate Endpoint (SUR): Blood pressure
Study 27780772 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 8735678 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30286130 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 24725198 — Surrogate Endpoint (SUR): Blood pressure
Study 24725198 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22345126 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22345126 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22345126 — Surrogate Endpoint (SUR): Blood pressure
Study 22345126 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15625424 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 12045365 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12045365 — Surrogate Endpoint (SUR): Blood pressure
Study 23859894 — Surrogate Endpoint (SUR): Blood pressure
Study 15028366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12796139 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 12796139 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12796139 — Predictive Biomarker (PRD): NE
Study 12796139 — Surrogate Endpoint (SUR): Blood pressure
Study 6383779 — Surrogate Endpoint (SUR): Blood pressure
Study 29853984 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 17212718 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2210795 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 31397126 — Surrogate Endpoint (SUR): Blood pressure
Study 31397126 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 12629445 — Surrogate Endpoint (SUR): Serum creatinine
Study 11003427 — Surrogate Endpoint (SUR): Serum calcium
Study 11003427 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 3002786 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20345732 — Surrogate Endpoint (SUR): Serum testosterone
Study 11684917 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25928356 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25928356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 22699800 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 16708528 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 16708528 — Surrogate Endpoint (SUR): Blood pressure
Study 8285455 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 21611944 — Predictive Biomarker (PRD): CRCP mRNA
Genes: CRCP
Study 21611944 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 27842499 — Surrogate Endpoint (SUR): Blood pressure
Study 24447332 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 24447332 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 10720584 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26743775 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16970088 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 10474785 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22976847 — Surrogate Endpoint (SUR): Blood pressure
Study 27017403 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 17519792 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 6460207 — Surrogate Endpoint (SUR): Blood pressure
Study 6460207 — Surrogate Endpoint (SUR): Serum potassium
Study 29192240 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 25764160 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25764160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25764160 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23846820 — Surrogate Endpoint (SUR): Blood pressure
Study 20618506 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 18251761 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19117319 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11247319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11247319 — Safety Biomarker (SAF): Interleukin 1
Study 8502260 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 3551212 — Surrogate Endpoint (SUR): Blood pressure
Study 20103775 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20103775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14586384 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 14586384 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 14586384 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 14586384 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 3011440 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3011440 — Surrogate Endpoint (SUR): Blood pressure
Study 1095262 — Surrogate Endpoint (SUR): Blood pressure
Study 1095262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1095262 — Surrogate Endpoint (SUR): Serum creatinine
Study 28835090 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 28835090 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23929930 — Surrogate Endpoint (SUR): Blood pressure
Study 18923232 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18923232 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 12456382 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22965961 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22965961 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study 22965961 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19944872 — Surrogate Endpoint (SUR): Blood pressure
Study 15044672 — Surrogate Endpoint (SUR): Blood pressure
Study 15044672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9787721 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23993326 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9350563 — Surrogate Endpoint (SUR): Probing pocket depth
Study 1778859 — Surrogate Endpoint (SUR): Serum creatinine
Study 7340890 — Surrogate Endpoint (SUR): Blood pressure
Study 29288184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25819697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21124000 — Safety Biomarker (SAF): Cytochrome c
Study 8940729 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 8940729 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3907967 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 27573605 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 3547214 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 19280185 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19280185 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 1105489 — Surrogate Endpoint (SUR): Blood pressure
Study 23757615 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 17259554 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15235928 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8513310 — Surrogate Endpoint (SUR): Blood pressure
Study 23311173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20624316 — Surrogate Endpoint (SUR): Blood pressure
Study 8573730 — Surrogate Endpoint (SUR): Blood pressure
Study 31564377 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 31564377 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 31564377 — Surrogate Endpoint (SUR): Bone mineral density
Study 23816023 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 21801326 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15193684 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15193684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27085660 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24581465 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2773895 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25140000 — Predictive Biomarker (PRD): EGFL7 mRNA
Genes: EGFL7; MEGF7; UNQ187/PRO1449
Study 25140000 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19148838 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 30586746 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 15449150 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9684137 — Monitoring Biomarker (MOI): HBV DNA
Study 1969567 — Surrogate Endpoint (SUR): Blood pressure
Study 23648352 — Surrogate Endpoint (SUR): Serum calcium
Study 15491247 — Surrogate Endpoint (SUR): Blood pressure
Study 18353632 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16850908 — Safety Biomarker (SAF): Reactive oxygen species
Study 12620695 — Surrogate Endpoint (SUR): Blood pressure
Study 9196432 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study 26685099 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20956707 — Surrogate Endpoint (SUR): Blood pressure
Study 17460371 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 29623516 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27194097 — Surrogate Endpoint (SUR): Blood pressure
Study 25001365 — Surrogate Endpoint (SUR): Blood pressure
Study 15707996 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 27181260 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 25043685 — Surrogate Endpoint (SUR): Serum creatinine
Study 15973546 — Surrogate Endpoint (SUR): Blood pressure
Study 14507948 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31278755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 31278755 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24977755 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31598823 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31598823 — Surrogate Endpoint (SUR): Blood pressure
Study 23417031 — Surrogate Endpoint (SUR): Serum potassium
Study 21036583 — Surrogate Endpoint (SUR): Blood pressure
Study 18080399 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18080399 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 18080399 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 15535413 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2841053 — Surrogate Endpoint (SUR): Blood pressure
Study 2841053 — Surrogate Endpoint (SUR): Serum sodium
Study 22936619 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19759166 — Surrogate Endpoint (SUR): Bone mineral density
Study 7923966 — Surrogate Endpoint (SUR): Serum creatinine
Study 27918762 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27918762 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25753207 — Predictive Biomarker (PRD): SNRPB mRNA
Genes: SNRPB; COD; SNRPB1
Study 9051855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22244035 — Surrogate Endpoint (SUR): Blood pressure
Study 29386413 — Surrogate Endpoint (SUR): Serum calcium
Study 29386413 — Surrogate Endpoint (SUR): Serum creatinine
Study 29386413 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10516692 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10516692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 7516191 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7516191 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31640647 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 18382267 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18382267 — Surrogate Endpoint (SUR): Blood pressure
Study 18382267 — Surrogate Endpoint (SUR): Serum creatinine
Study 18382267 — Surrogate Endpoint (SUR): Serum potassium
Study 12004637 — Surrogate Endpoint (SUR): Blood pressure
Study 7806038 — Monitoring Biomarker (MOI): HBV DNA
Study 30379222 — Surrogate Endpoint (SUR): Serum creatinine
Study 10687884 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26342472 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 24712378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24712378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22668852 — Surrogate Endpoint (SUR): Blood pressure
Study 17569128 — Monitoring Biomarker (MOI): HBV DNA
Study 15305694 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9794107 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21161264 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19109444 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 27664457 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27664457 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 21880242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21880242 — Surrogate Endpoint (SUR): Blood pressure
Study 19662998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19662998 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17536872 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17536872 — Surrogate Endpoint (SUR): Serum creatinine
Study 9868668 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15617457 — Surrogate Endpoint (SUR): Blood pressure
Study 8342904 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8342904 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 8342904 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27575024 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27575024 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 11869846 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 20934731 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16461044 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16461044 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 28464211 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 28464211 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28464211 — Predictive Biomarker (PRD): Hormone receptor
Study 25653079 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25172379 — Surrogate Endpoint (SUR): Blood pressure
Study 25172379 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2466024 — Surrogate Endpoint (SUR): Blood pressure
Study 24791863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22331829 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 22331829 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22331829 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22331829 — Predictive Biomarker (PRD): MYLIP mRNA
Genes: MYLIP; BZF1; IDOL; BM-023; PP5242
Study 22331829 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 22331829 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 22331829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17222115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15804151 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 12584830 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12584830 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12584830 — Surrogate Endpoint (SUR): Serum creatinine
Study 30706439 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 28314866 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9820611 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 20130074 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 24773166 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 22932119 — Surrogate Endpoint (SUR): Serum sodium
Study 17632760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17632760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25039804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28279484 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 26164786 — Surrogate Endpoint (SUR): Blood pressure
Study 21641636 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21641636 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21641636 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 20154337 — Surrogate Endpoint (SUR): Blood pressure
Study 18772641 — Surrogate Endpoint (SUR): Blood pressure
Study 14870884 — Surrogate Endpoint (SUR): Serum calcium
Study 17121590 — Surrogate Endpoint (SUR): Urine free cortisol
Study 6272242 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29633238 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 29633238 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29633238 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 29633238 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25889643 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23757457 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 21860572 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 18192039 — Surrogate Endpoint (SUR): Blood pressure
Study 31420055 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 29415828 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25153575 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 3072178 — Surrogate Endpoint (SUR): Blood pressure
Study 22114899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22114899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22114899 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22114899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18609065 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10996351 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10996351 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7013868 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 16449211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20118486 — Surrogate Endpoint (SUR): Serum creatinine
Study 8267058 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8267058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6129077 — Surrogate Endpoint (SUR): Blood pressure
Study 31451249 — Surrogate Endpoint (SUR): Blood pressure
Study 30063644 — Surrogate Endpoint (SUR): Blood pressure
Study 12952369 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19029264 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 25943394 — Surrogate Endpoint (SUR): Blood pressure
Study 23052515 — Surrogate Endpoint (SUR): Blood pressure
Study 11807305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10072411 — Surrogate Endpoint (SUR): Serum creatinine
Study 31228055 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 31228055 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI