TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31118099 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 24165068 — Surrogate Endpoint (SUR): Blood pressure
Study 8957033 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25454870 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25454870 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25454870 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 19201650 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19201650 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19201650 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 19201650 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17429343 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 17429343 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11269613 — Surrogate Endpoint (SUR): Urinary oxalate
Study 28295869 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 19828704 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 19828704 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 19828704 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 16914703 — Surrogate Endpoint (SUR): Bone mineral density
Study 6366126 — Surrogate Endpoint (SUR): Serum creatinine
Study 22033742 — Surrogate Endpoint (SUR): Blood pressure
Study 16942934 — Surrogate Endpoint (SUR): Blood pressure
Study 9366103 — Surrogate Endpoint (SUR): Blood pressure
Study 9366103 — Surrogate Endpoint (SUR): Serum potassium
Study 9876229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23221935 — Surrogate Endpoint (SUR): Blood pressure
Study 17050212 — Surrogate Endpoint (SUR): Blood pressure
Study 8774056 — Surrogate Endpoint (SUR): Bone mineral density
Study 8774056 — Surrogate Endpoint (SUR): Serum calcium
Study 2065506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22389273 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18398307 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10912985 — Surrogate Endpoint (SUR): Blood pressure
Study 9072226 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23775574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11345361 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11097664 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9494056 — Surrogate Endpoint (SUR): Blood pressure
Study 3668249 — Surrogate Endpoint (SUR): Blood pressure
Study 18234328 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 23885521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23885521 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23885521 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23283393 — Safety Biomarker (SAF): Th2 cell
Study 23283393 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 23283393 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15046683 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8575136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2791446 — Surrogate Endpoint (SUR): Blood pressure
Study 18755849 — Surrogate Endpoint (SUR): Serum creatinine
Study 16795983 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16795983 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16795983 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6229319 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24197880 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20946966 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 19273465 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 9292621 — Predictive Biomarker (PRD): RAPH1 mRNA
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 23919622 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19401546 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 19401546 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11273790 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7525634 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26933398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25633712 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25633712 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 11780441 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30354558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30354558 — Safety Biomarker (SAF): Interleukin 1
Study 30354558 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24769399 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 12800859 — Surrogate Endpoint (SUR): Blood pressure
Study 12800859 — Surrogate Endpoint (SUR): Plasma ammonia
Study 8919651 — Surrogate Endpoint (SUR): Serum creatinine
Study 6435484 — Surrogate Endpoint (SUR): Blood pressure
Study 10629930 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 6101934 — Surrogate Endpoint (SUR): Blood pressure
Study 28976976 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 19744006 — Safety Biomarker (SAF): DRD3
Study 20839665 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 18302514 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 18302514 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18302514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2844492 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2844492 — Surrogate Endpoint (SUR): Blood pressure
Study 23137954 — Surrogate Endpoint (SUR): Blood pressure
Study 18638709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18638709 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17051484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15339579 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15339579 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 10966000 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 29374658 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9457389 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9457389 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29526844 — Predictive Biomarker (PRD): P2RY12 mRNA
Genes: P2RY12; HORK3
Study 29526844 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 24444682 — Surrogate Endpoint (SUR): Serum creatinine
Study 24444682 — Surrogate Endpoint (SUR): Serum potassium
Study 24444682 — Surrogate Endpoint (SUR): Serum sodium
Study 21075452 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 26291092 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 19169168 — Surrogate Endpoint (SUR): Bone mineral density
Study 17061459 — Surrogate Endpoint (SUR): Blood pressure
Study 9208356 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9208356 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30629813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28419398 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28419398 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 25178900 — Surrogate Endpoint (SUR): Blood pressure
Study 19404172 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 17498003 — Surrogate Endpoint (SUR): Serum calcium
Study 17498003 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 12053057 — Surrogate Endpoint (SUR): Serum potassium
Study 8021483 — Surrogate Endpoint (SUR): Blood pressure
Study 8021483 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2478793 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16236380 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16236380 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8328996 — Surrogate Endpoint (SUR): Blood pressure
Study 9818662 — Surrogate Endpoint (SUR): Blood pressure
Study 25644584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20724185 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 20724185 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 20724185 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17995980 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18852657 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 10192648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7000346 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 28800861 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 14998429 — Surrogate Endpoint (SUR): Blood pressure
Study 26990963 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22855392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22855392 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 22855392 — Safety Biomarker (SAF): Interleukin 1
Study 22855392 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22855392 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 22855392 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12959310 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12959310 — Surrogate Endpoint (SUR): Blood pressure
Study 30820567 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 28088207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28088207 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28088207 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18781079 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 12659599 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12659599 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10849529 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9356086 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30567497 — Surrogate Endpoint (SUR): Blood pressure
Study 15842549 — Surrogate Endpoint (SUR): Blood pressure
Study 2683541 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30396181 — Surrogate Endpoint (SUR): Blood pressure
Study 19949019 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19949019 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19949019 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19949019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23720247 — Surrogate Endpoint (SUR): Blood pressure
Study 27776221 — Monitoring Biomarker (MOI): Procalcitonin
Study 26059521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23899468 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 23899468 — Surrogate Endpoint (SUR): Bone mineral density
Study 23899468 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23899468 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11209089 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11209089 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 11209089 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31517322 — Predictive Biomarker (PRD): ERF mRNA
Genes: ERF
Study 25273554 — Surrogate Endpoint (SUR): Blood pressure
Study 2940301 — Safety Biomarker (SAF): Interleukin 1
Study 20691435 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20691435 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 18173341 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 10099857 — Safety Biomarker (SAF): DRD2
Study 1651201 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 1651201 — Surrogate Endpoint (SUR): Blood pressure
Study 31686768 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26135532 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 31003673 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study 28493030 — Surrogate Endpoint (SUR): Blood pressure
Study 25304294 — Predictive Biomarker (PRD): DPEP1 mRNA
Genes: DPEP1; MDP; RDP
Study 23989947 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8181800 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8181800 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 30343531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22717286 — Surrogate Endpoint (SUR): Blood pressure
Study 12110062 — Surrogate Endpoint (SUR): Bone mineral density
Study 30039991 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30115425 — Surrogate Endpoint (SUR): Blood pressure
Study 22873530 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17786056 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17786056 — Surrogate Endpoint (SUR): Blood pressure
Study 15027165 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 25643028 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 10937952 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10937952 — Surrogate Endpoint (SUR): Blood pressure
Study 12450697 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10803488 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10803488 — Surrogate Endpoint (SUR): Blood pressure
Study 31709879 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 31709879 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21707766 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 15161789 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 30660196 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 28318997 — Surrogate Endpoint (SUR): Blood pressure
Study 27543885 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 27543885 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 22913890 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22913890 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17654442 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17654442 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 6118058 — Surrogate Endpoint (SUR): Blood pressure
Study 9860145 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 9860145 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 9860145 — Predictive Biomarker (PRD): GNL3 mRNA
Genes: GNL3; E2IG3; NS
Study 9860145 — Surrogate Endpoint (SUR): Blood pressure
Study 7719388 — Surrogate Endpoint (SUR): Blood pressure
Study 2223582 — Predictive Biomarker (PRD): PRLR mRNA
Genes: PRLR
Study 7368968 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28425827 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11035676 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11035676 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31655598 — Predictive Biomarker (PRD): OSCAR mRNA
Genes: OSCAR
Study 25883112 — Predictive Biomarker (PRD): SLC27A1 mRNA
Genes: SLC27A1; ACSVL5; FATP1
Study 18521090 — Predictive Biomarker (PRD); Safety Biomarker (SAF): NPAS3 mRNA
Genes: NPAS3; BHLHE12; MOP6; PASD6
Study 18521090 — Predictive Biomarker (PRD): XK mRNA
Genes: XK; XKR1; XRG1
Study 18521090 — Predictive Biomarker (PRD): XKR4 mRNA
Genes: XKR4; KIAA1889; XRG4
Study 18521090 — Predictive Biomarker (PRD): TNR mRNA
Genes: TNR
Study 18521090 — Predictive Biomarker (PRD): GRIA4 mRNA
Genes: GRIA4; GLUR4
Study 18521090 — Predictive Biomarker (PRD): GFRA2 mRNA
Genes: GFRA2; GDNFRB; RETL2; TRNR2
Study 18521090 — Predictive Biomarker (PRD): HTR7 mRNA
Genes: HTR7
Study 28972854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24887223 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 24887223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27695944 — Safety Biomarker (SAF): Hyaluronic acid
Study 7800739 — Surrogate Endpoint (SUR): Blood pressure
Study 30977089 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 30977089 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30742692 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 28535933 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28535933 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 28535933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23899426 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 31451954 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31451954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26176708 — Surrogate Endpoint (SUR): Blood pressure
Study 24810493 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 24810493 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 24810493 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 24810493 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24810493 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24810493 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 24810493 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 24810493 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20233513 — Monitoring Biomarker (MOI): Procalcitonin
Study 11774064 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 9519219 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 15126003 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15126003 — Surrogate Endpoint (SUR): Blood pressure
Study 31539601 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27722772 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 27722772 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20598983 — Surrogate Endpoint (SUR): Serum creatinine
Study 14602746 — Surrogate Endpoint (SUR): Bone mineral density
Study 30954146 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 9714692 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9714692 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9714692 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 8313807 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8313807 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 12702132 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12702132 — Safety Biomarker (SAF): Human leucocyte antigen
Study 10878501 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22486226 — Surrogate Endpoint (SUR): Blood pressure
Study 20427749 — Surrogate Endpoint (SUR): Serum calcium
Study 16095500 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 12360162 — Surrogate Endpoint (SUR): Blood pressure
Study 10366224 — Predictive Biomarker (PRD): ATXN1 mRNA
Genes: ATXN1; ATX1; SCA1
Study 10366224 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 10366224 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 31743809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14687239 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 14687239 — Surrogate Endpoint (SUR): Blood pressure
Study 10899847 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 10899847 — Predictive Biomarker (PRD): CLSTN2 mRNA
Genes: CLSTN2; CS2
Study 10899847 — Predictive Biomarker (PRD): CLSTN1 mRNA
Genes: CLSTN1; CS1; KIAA0911
Study 8101082 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8101082 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8101082 — Surrogate Endpoint (SUR): Blood pressure
Study 31550941 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20