TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7956214 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7956214 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26568428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1610995 — Surrogate Endpoint (SUR): Blood pressure
Study 24007426 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24007426 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 24007426 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12563673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12563673 — Safety Biomarker (SAF): Reactive oxygen species
Study 8422345 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8422345 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12610740 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 12610740 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7668493 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31620980 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23460074 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23460074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17295587 — Predictive Biomarker (PRD): TNR mRNA
Genes: TNR
Study 3886563 — Surrogate Endpoint (SUR): Blood pressure
Study 2248082 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 2248082 — Surrogate Endpoint (SUR): Blood pressure
Study 9727959 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 9727959 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 2531910 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 30318492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30318492 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18321497 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 16544440 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16544440 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2167788 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15715193 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7564350 — Surrogate Endpoint (SUR): Blood pressure
Study 7188585 — Surrogate Endpoint (SUR): Blood pressure
Study 21217456 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 16639069 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23026438 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20740685 — Surrogate Endpoint (SUR): Bone mineral density
Study 16887429 — Surrogate Endpoint (SUR): Serum creatinine
Study 16887429 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2539937 — Surrogate Endpoint (SUR): Blood pressure
Study 28619771 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 25814638 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 10523398 — Surrogate Endpoint (SUR): Blood pressure
Study 8750123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8750123 — Safety Biomarker (SAF): Interleukin 1
Study 8750123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6145480 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26654154 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26654154 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10599886 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7476738 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7476738 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 30176553 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21180001 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 17708284 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9814503 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 9814503 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 9814503 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9814503 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2536257 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29330230 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22800624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20545479 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17121051 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 17121051 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23475448 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23475448 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11737381 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8583814 — Surrogate Endpoint (SUR): Blood pressure
Study 6228469 — Predictive Biomarker (PRD): CLYBL mRNA
Genes: CLYBL; CLB
Study 11575230 — Surrogate Endpoint (SUR): Blood pressure
Study 8706062 — Surrogate Endpoint (SUR): Blood pressure
Study 5035 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22094481 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 19919976 — Surrogate Endpoint (SUR): Blood pressure
Study 19919976 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 9347661 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 22635965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22635965 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22635965 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 20152214 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31865282 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31865282 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 25884980 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19423110 — Surrogate Endpoint (SUR): Blood pressure
Study 2680083 — Surrogate Endpoint (SUR): Blood pressure
Study 20843556 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15825976 — Surrogate Endpoint (SUR): Blood pressure
Study 1520045 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1520045 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30895459 — Surrogate Endpoint (SUR): Blood pressure
Study 22569288 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22569288 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20437055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28816883 — Surrogate Endpoint (SUR): Blood pressure
Study 26132827 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 26132827 — Safety Biomarker (SAF): IL-6 and IL-10
Study 26132827 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 19948946 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 10589361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26921267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17370037 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17370037 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9539583 — Surrogate Endpoint (SUR): Blood pressure
Study 8586834 — Surrogate Endpoint (SUR): Blood pressure
Study 2710909 — Surrogate Endpoint (SUR): Blood pressure
Study 902626 — Surrogate Endpoint (SUR): Blood pressure
Study 25291152 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 7272896 — Predictive Biomarker (PRD): CNDP2 mRNA
Genes: CNDP2; CN2; CPGL; HEL-S-13; PEPA
Study 30496024 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28270491 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 26797215 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 26797215 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11887193 — Surrogate Endpoint (SUR): Blood pressure
Study 27803120 — Surrogate Endpoint (SUR): Blood pressure
Study 26829443 — Surrogate Endpoint (SUR): Blood pressure
Study 9855322 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 799958 — Surrogate Endpoint (SUR): Blood pressure
Study 31325802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31325802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21972626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18390974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18390974 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10407512 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 20567002 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 20567002 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 14633521 — Surrogate Endpoint (SUR): Blood pressure
Study 15839182 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11716200 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30734583 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 18223492 — Surrogate Endpoint (SUR): Bone mineral density
Study 20102775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20102775 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20102775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9829540 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25080293 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 22396129 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18525041 — Surrogate Endpoint (SUR): Blood pressure
Study 26863353 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 26863353 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21422800 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21422800 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 21422800 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 17323015 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12172882 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 9604124 — Surrogate Endpoint (SUR): Blood pressure
Study 28454801 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 28454801 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26424460 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 23727422 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 15653003 — Surrogate Endpoint (SUR): Bone mineral density
Study 8756735 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26987975 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 22527063 — Surrogate Endpoint (SUR): Blood pressure
Study 16901550 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11427219 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26599707 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 26599707 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 26599707 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 10227630 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 10227630 — Safety Biomarker (SAF): BDNF
Study 10227630 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7782581 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23168581 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 23168581 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 23168581 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 20164296 — Surrogate Endpoint (SUR): Bone mineral density
Study 18478937 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25751447 — Surrogate Endpoint (SUR): Blood pressure
Study 17653011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17653011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17653011 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16671340 — Surrogate Endpoint (SUR): Blood pressure
Study 30778518 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 26436683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26436683 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20732768 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20732768 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 20732768 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 3320785 — Surrogate Endpoint (SUR): Blood pressure
Study 19590482 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 16876164 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study 6463598 — Surrogate Endpoint (SUR): Serum calcium
Study 30802196 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30802196 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 30802196 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 30802196 — Surrogate Endpoint (SUR): Blood pressure
Study 28619016 — Surrogate Endpoint (SUR): Blood pressure
Study 14709941 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 21816979 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19890022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19890022 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17048576 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29443823 — Surrogate Endpoint (SUR): Blood pressure
Study 15932366 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 10583036 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8904726 — Surrogate Endpoint (SUR): Blood pressure
Study 27354646 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23247938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10475722 — Surrogate Endpoint (SUR): Blood pressure
Study 30726969 — Predictive Biomarker (PRD): HCAR2 mRNA
Genes: HCAR2; GPR109A; HCA2; HM74A; NIACR1
Study 30726969 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27821724 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16396628 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10493476 — Surrogate Endpoint (SUR): Blood pressure
Study 31863227 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30266356 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 20460116 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 11231856 — Safety Biomarker (SAF): IL-6 and IL-10
Study 11231856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2455778 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 30799192 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19441668 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 16687967 — Surrogate Endpoint (SUR): Blood pressure
Study 14728846 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 14728846 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10775075 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 31665017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22920048 — Surrogate Endpoint (SUR): Blood pressure
Study 20519552 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 20519552 — Safety Biomarker (SAF): MATE1
Genes: SLC47A1; FLJ10847
Study 17602170 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 15074091 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11677003 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2768768 — Surrogate Endpoint (SUR): Blood pressure
Study 25328079 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25328079 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24942407 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21147691 — Surrogate Endpoint (SUR): Bone mineral density
Study 17991545 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 8903900 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1708910 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28973620 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 28973620 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 28973620 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 12554614 — Surrogate Endpoint (SUR): Blood pressure
Study 8857018 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8857018 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31145689 — Safety Biomarker (SAF): Reactive oxygen species
Study 28462892 — Surrogate Endpoint (SUR): Serum creatinine
Study 17109346 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10775074 — Surrogate Endpoint (SUR): Serum creatinine
Study 8990355 — Surrogate Endpoint (SUR): Serum creatinine
Study 8931848 — Surrogate Endpoint (SUR): Blood pressure
Study 31388739 — Surrogate Endpoint (SUR): Blood pressure
Study 15723969 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15723969 — Surrogate Endpoint (SUR): Blood pressure
Study 2345633 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26803355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20411995 — Surrogate Endpoint (SUR): Blood pressure
Study 12651051 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10824717 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 6323866 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18407341 — Surrogate Endpoint (SUR): Serum creatinine
Study 10100178 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8889353 — Surrogate Endpoint (SUR): Blood pressure
Study 1905631 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7104149 — Surrogate Endpoint (SUR): Blood pressure
Study 30650288 — Predictive Biomarker (PRD): MAP3K7 mRNA
Genes: MAP3K7; TAK1
Study 30650288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30650288 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30650288 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16279916 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 6636033 — Surrogate Endpoint (SUR): Blood pressure
Study 6636033 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30399034 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19043656 — Surrogate Endpoint (SUR): Bone mineral density
Study 8848888 — Surrogate Endpoint (SUR): Blood pressure
Study 30999963 — Surrogate Endpoint (SUR): Blood pressure
Study 12742557 — Surrogate Endpoint (SUR): Bone mineral density
Study 20185637 — Surrogate Endpoint (SUR): Serum sodium
Study 16322336 — Surrogate Endpoint (SUR): Bone mineral density
Study 8541695 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 31812554 — Predictive Biomarker (PRD): Microsatellite instability
Study 25845768 — Surrogate Endpoint (SUR): Blood pressure
Study 23379590 — Surrogate Endpoint (SUR): Serum calcium
Study 21113641 — Surrogate Endpoint (SUR): Blood pressure
Study 31944420 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 20556561 — Surrogate Endpoint (SUR): Blood pressure
Study 10229292 — Surrogate Endpoint (SUR): Blood pressure
Study 10229292 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21377930 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2842146 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26571884 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 26275164 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16436892 — Surrogate Endpoint (SUR): Blood pressure
Study 19894018 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341