TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9252957 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16632013 — Surrogate Endpoint (SUR): Serum creatinine
Study 16632013 — Surrogate Endpoint (SUR): Blood pressure
Study 8139394 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29368598 — Surrogate Endpoint (SUR): Blood pressure
Study 11998881 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9894621 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9894621 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28738490 — Surrogate Endpoint (SUR): Blood pressure
Study 14618096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14618096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 14618096 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30025819 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27514617 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24522636 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18793808 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18793808 — Surrogate Endpoint (SUR): Serum creatinine
Study 16144987 — Surrogate Endpoint (SUR): Blood pressure
Study 12117040 — Surrogate Endpoint (SUR): Serum potassium
Study 2140965 — Surrogate Endpoint (SUR): Blood pressure
Study 29555631 — Predictive Biomarker (PRD): CD101 mRNA
Genes: CD101; EWI101; IGSF2; V7
Study 24738800 — Surrogate Endpoint (SUR): Blood pressure
Study 7290755 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 7290755 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 27717222 — Safety Biomarker (SAF): DRD2
Study 22028071 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 22028071 — Surrogate Endpoint (SUR): Blood pressure
Study 22028071 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22028071 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 2566391 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21834970 — Surrogate Endpoint (SUR): Blood pressure
Study 14678587 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1734400 — Surrogate Endpoint (SUR): Blood pressure
Study 22500389 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22500389 — Surrogate Endpoint (SUR): Serum creatinine
Study 12859305 — Surrogate Endpoint (SUR): Blood pressure
Study 3957482 — Surrogate Endpoint (SUR): Blood pressure
Study 3957482 — Surrogate Endpoint (SUR): Serum potassium
Study 17942181 — Surrogate Endpoint (SUR): Blood pressure
Study 14624765 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 27652610 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 19848211 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17224344 — Surrogate Endpoint (SUR): Blood pressure
Study 17224344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29127842 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22702846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21785174 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21785174 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 21785174 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15496639 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15496639 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30153359 — Predictive Biomarker (PRD): LOXL2 mRNA
Genes: LOXL2
Study 26209038 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26209038 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 26209038 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24180000 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19014338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3260083 — Surrogate Endpoint (SUR): Blood pressure
Study 26333513 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 12708129 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10759770 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3891769 — Surrogate Endpoint (SUR): Blood pressure
Study 11407971 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 2888795 — Surrogate Endpoint (SUR): Blood pressure
Study 18812325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21510527 — Surrogate Endpoint (SUR): Blood pressure
Study 18633172 — Surrogate Endpoint (SUR): Blood pressure
Study 11236242 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11236242 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11236242 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 30067592 — Surrogate Endpoint (SUR): Serum calcium
Study 1623994 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28231835 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28231835 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 28231835 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15577178 — Surrogate Endpoint (SUR): Bone mineral density
Study 27925651 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22963982 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 7733075 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 7305653 — Surrogate Endpoint (SUR): Serum creatinine
Study 7305653 — Surrogate Endpoint (SUR): Blood pressure
Study 22075818 — Surrogate Endpoint (SUR): Blood pressure
Study 19656771 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22108523 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18089623 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 18089623 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18089623 — Surrogate Endpoint (SUR): Blood pressure
Study 24015666 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 10735688 — Surrogate Endpoint (SUR): Serum creatinine
Study 24065124 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 21972425 — Surrogate Endpoint (SUR): Blood pressure
Study 21190455 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21190455 — Surrogate Endpoint (SUR): Blood pressure
Study 8835632 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8835632 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8584604 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24372155 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25358424 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 19879596 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17012863 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21545399 — Surrogate Endpoint (SUR): Blood pressure
Study 14756387 — Surrogate Endpoint (SUR): Blood pressure
Study 20089204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19127918 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 10918946 — Surrogate Endpoint (SUR): Serum creatinine
Study 6510452 — Surrogate Endpoint (SUR): Blood pressure
Study 17252564 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 25070350 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25070350 — Surrogate Endpoint (SUR): Blood pressure
Study 16430412 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 16430412 — Surrogate Endpoint (SUR): Blood pressure
Study 10857518 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30374692 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30374692 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 23141813 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 19952829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9550531 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7840527 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 3295323 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 25947930 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 12883897 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1826871 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31023403 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31023403 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31023403 — Surrogate Endpoint (SUR): Blood pressure
Study 24345165 — Safety Biomarker (SAF): DRD2
Study 17726460 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 17726460 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 11756645 — Surrogate Endpoint (SUR): Plasma ammonia
Study 17646243 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17646243 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15980691 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8724034 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30010698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30010698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30010698 — Surrogate Endpoint (SUR): Blood pressure
Study 30010698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24660759 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 10073603 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10073603 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10073603 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31089768 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24067348 — Surrogate Endpoint (SUR): Blood pressure
Study 12499320 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 31074823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25239019 — Predictive Biomarker (PRD): GNS mRNA
Genes: GNS
Study 21756323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14679315 — Surrogate Endpoint (SUR): Blood pressure
Study 15125484 — Surrogate Endpoint (SUR): Blood pressure
Study 24119823 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 30980315 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 16197583 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 9987085 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2106274 — Surrogate Endpoint (SUR): Blood pressure
Study 26635229 — Surrogate Endpoint (SUR): Blood pressure
Study 23345581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23345581 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18640465 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18640465 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29277099 — Surrogate Endpoint (SUR): Blood pressure
Study 29277099 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10220941 — Surrogate Endpoint (SUR): Blood pressure
Study 7027892 — Surrogate Endpoint (SUR): Blood pressure
Study 7027892 — Surrogate Endpoint (SUR): Serum uric acid
Study 29177434 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 29177434 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 19755930 — Predictive Biomarker (PRD): ZMYM2 mRNA
Genes: ZMYM2; FIM; RAMP; ZNF198
Study 11367689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28873511 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 24941840 — Predictive Biomarker (PRD): CXCL16 mRNA
Genes: CXCL16; SCYB16; SRPSOX; UNQ2759/PRO6714
Study 24941840 — Predictive Biomarker (PRD): ADAM10 mRNA
Genes: ADAM10; KUZ; MADM
Study 24941840 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 24941840 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16454441 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15060505 — Surrogate Endpoint (SUR): Blood pressure
Study 9362403 — Surrogate Endpoint (SUR): Blood pressure
Study 31029069 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28622115 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 30739584 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 15879427 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 15879427 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 12794265 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 1464208 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 31551219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31551219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11858378 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11858378 — Surrogate Endpoint (SUR): Serum creatinine
Study 11858378 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25058803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31464020 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31464020 — Surrogate Endpoint (SUR): Blood pressure
Study 17587396 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 17587396 — Surrogate Endpoint (SUR): Blood pressure
Study 17587396 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15579728 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 15579728 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26123356 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 19112061 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 17977159 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 31056441 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 31056441 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 19154473 — Predictive Biomarker (PRD): NMI mRNA
Genes: NMI
Study 24814528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24814528 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22747647 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 18850554 — Safety Biomarker (SAF): Hyaluronic acid
Study 15911747 — Surrogate Endpoint (SUR): Blood pressure
Study 12370858 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12370858 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1980278 — Surrogate Endpoint (SUR): Blood pressure
Study 9645459 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8194689 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 24855155 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 18333862 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28437675 — Safety Biomarker (SAF): miR-142
Genes: MIR142
Study 26766141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22594467 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 19376787 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 12862326 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27926633 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15579570 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10390000 — Predictive Biomarker (PRD): Cancer-associated serum antigen
Study 419454 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16713009 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 16713009 — Surrogate Endpoint (SUR): Blood pressure
Study 11747380 — Surrogate Endpoint (SUR): Blood pressure
Study 3325229 — Surrogate Endpoint (SUR): Blood pressure
Study 23906445 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 23906445 — Surrogate Endpoint (SUR): Bone mineral density
Study 23796693 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15562383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12217138 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 10359391 — Surrogate Endpoint (SUR): Serum testosterone
Study 10359391 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27677502 — Predictive Biomarker (PRD): PINK1 mRNA
Genes: PINK1
Study 27677502 — Predictive Biomarker (PRD): BNIP3 mRNA
Genes: BNIP3; NIP3
Study 27677502 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27677502 — Predictive Biomarker (PRD): TFEB mRNA
Genes: TFEB; BHLHE35
Study 24899662 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 22565110 — Surrogate Endpoint (SUR): Blood pressure
Study 8777826 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8777826 — Surrogate Endpoint (SUR): Blood pressure
Study 1381788 — Surrogate Endpoint (SUR): Blood pressure
Study 1381788 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31618706 — Surrogate Endpoint (SUR): Blood pressure
Study 22174437 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 22174437 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 19954944 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19954944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19954944 — Predictive Biomarker (PRD): GIPR mRNA
Genes: GIPR
Study 15027055 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 25857271 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25857271 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25857271 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15221494 — Surrogate Endpoint (SUR): Bone mineral density
Study 11592566 — Surrogate Endpoint (SUR): Bone mineral density
Study 25924030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21765364 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17326999 — Predictive Biomarker (PRD): AQP8 mRNA
Genes: AQP8
Study 11333840 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 11333840 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 8288071 — Surrogate Endpoint (SUR): Blood pressure
Study 29625879 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 18444945 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 18444945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16596905 — Surrogate Endpoint (SUR): Sperm parameters
Study 11382894 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 3512188 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12734787 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12734787 — Surrogate Endpoint (SUR): Blood pressure
Study 20958890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12562653 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 9339937 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9339937 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8219141 — Surrogate Endpoint (SUR): Blood pressure
Study 19620518 — Surrogate Endpoint (SUR): Blood pressure
Study 19620518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8268898 — Surrogate Endpoint (SUR): Blood pressure
Study 21782923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20145433 — Surrogate Endpoint (SUR): Blood pressure
Study 20145433 — Surrogate Endpoint (SUR): Serum creatinine
Study 20145433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15823831 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11916779 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1679391 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 22572632 — Surrogate Endpoint (SUR): Blood pressure
Study 19619443 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11495215 — Surrogate Endpoint (SUR): Blood pressure
Study 9306352 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29856692 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 25385735 — Predictive Biomarker (PRD): PCA3
Study 2547470 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2547470 — Surrogate Endpoint (SUR): Blood pressure
Study 24091981 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 8815686 — Monitoring Biomarker (MOI): HBV DNA