TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22908326 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18639771 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study 18639771 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6817123 — Surrogate Endpoint (SUR): Blood pressure
Study 21821813 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21821813 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 16279283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12390056 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6180050 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31730466 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 31730466 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29362205 — Surrogate Endpoint (SUR): Blood pressure
Study 25011661 — Surrogate Endpoint (SUR): Blood pressure
Study 17515403 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12619921 — Surrogate Endpoint (SUR): Bone mineral density
Study 25979833 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25979833 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25979833 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 23359491 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 2450234 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31338868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23456732 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9589229 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 19433387 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 19433387 — Predictive Biomarker (PRD): Hormone receptor
Study 19433387 — Surrogate Endpoint (SUR): Bone mineral density
Study 16772708 — Surrogate Endpoint (SUR): Serum creatinine
Study 22405251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16291411 — Surrogate Endpoint (SUR): Blood pressure
Study 31059697 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 23818121 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 16495695 — Predictive Biomarker (PRD): PLAT mRNA
Genes: PLAT
Study 12795812 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8248660 — Surrogate Endpoint (SUR): Blood pressure
Study 8248660 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22090363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22090363 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22090363 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22090363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12379550 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7181738 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7181738 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25847554 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25847554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25847554 — Surrogate Endpoint (SUR): Blood pressure
Study 23545664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23545664 — Surrogate Endpoint (SUR): Blood pressure
Study 24721903 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study 24721903 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 12488953 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 25956750 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 25956750 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 25956750 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 17804473 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17804473 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11950430 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11950430 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10226398 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 27055521 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 18474451 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9843762 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 28008145 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 28008145 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 19708000 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19708000 — Surrogate Endpoint (SUR): Blood pressure
Study 22117083 — Predictive Biomarker (PRD): MOBP mRNA
Genes: MOBP
Study 22117083 — Surrogate Endpoint (SUR): Blood pressure
Study 20420104 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16444435 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8252957 — Surrogate Endpoint (SUR): Blood pressure
Study 30615231 — Surrogate Endpoint (SUR): Blood pressure
Study 29573224 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 27480654 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22093109 — Predictive Biomarker (PRD): DEFA1 mRNA
Genes: DEFA1; DEF1; DEFA2; MRS; DEFA1B
Study 20407630 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17879544 — Surrogate Endpoint (SUR): Blood pressure
Study 12142119 — Safety Biomarker (SAF): KCNH2
Genes: Kv11.1; HERG; erg1
Study 10442116 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 375433 — Surrogate Endpoint (SUR): Serum creatinine
Study 19541014 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11252073 — Surrogate Endpoint (SUR): Serum testosterone
Study 9333879 — Surrogate Endpoint (SUR): Bone mineral density
Study 3551506 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 25387876 — Predictive Biomarker (PRD): SFR1 mRNA
Genes: SFR1; C10orf78; MEI5; MEIR5
Study 21681167 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 21681167 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7877117 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7877117 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 7877117 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 7877117 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29583066 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29583066 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21667009 — Predictive Biomarker (PRD): INPP5J mRNA
Genes: INPP5J; PIB5PA; PIPP
Study 15585987 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 15585987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29637820 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 31502637 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 29571976 — Safety Biomarker (SAF): Reactive oxygen species
Study 27994066 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 24285428 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 12518180 — Surrogate Endpoint (SUR): Blood pressure
Study 12518180 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29091570 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 24853043 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 15097240 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 15097240 — Surrogate Endpoint (SUR): Blood pressure
Study 9286892 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9286892 — Surrogate Endpoint (SUR): Blood pressure
Study 23139614 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19465554 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 19465554 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 19465554 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2192018 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30003521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19142106 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17381399 — Surrogate Endpoint (SUR): Serum creatinine
Study 15133405 — Surrogate Endpoint (SUR): Blood pressure
Study 31089282 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 2664522 — Surrogate Endpoint (SUR): Blood pressure
Study 18460483 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12754275 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 12754275 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 12754275 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19065891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10235449 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 396086 — Surrogate Endpoint (SUR): Blood pressure
Study 19737321 — Surrogate Endpoint (SUR): Serum calcium
Study 11500333 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11500333 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28444964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12728160 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10810433 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 6506819 — Surrogate Endpoint (SUR): Blood pressure
Study 30126775 — Surrogate Endpoint (SUR): Bone mineral density
Study 29587159 — Predictive Biomarker (PRD): MEST mRNA
Genes: MEST; PEG1
Study 29579327 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28213365 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28213365 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26453484 — Surrogate Endpoint (SUR): Blood pressure
Study 26909888 — Surrogate Endpoint (SUR): Blood pressure
Study 20688033 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17506001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11721446 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2301243 — Surrogate Endpoint (SUR): Blood pressure
Study 7436639 — Surrogate Endpoint (SUR): Blood pressure
Study 10652956 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 10652956 — Surrogate Endpoint (SUR): Bone mineral density
Study 9330124 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1534042 — Surrogate Endpoint (SUR): Blood pressure
Study 16284466 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 12882907 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 1806186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22047909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 15705728 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23832605 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 17030655 — Surrogate Endpoint (SUR): Blood pressure
Study 9734743 — Surrogate Endpoint (SUR): Blood pressure
Study 2538676 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31977371 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21653735 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 21653735 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 19361304 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16997737 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9191528 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18212288 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11303311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11303311 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11303311 — Surrogate Endpoint (SUR): Bone mineral density
Study 31688451 — Predictive Biomarker (PRD): PDE10A mRNA
Genes: PDE10A
Study 27271613 — Safety Biomarker (SAF): miR-18a
Genes: MIR18A
Study 17415555 — Surrogate Endpoint (SUR): Blood pressure
Study 12669751 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 25566730 — Surrogate Endpoint (SUR): Bone mineral density
Study 24722500 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 7664433 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16317106 — Surrogate Endpoint (SUR): Blood pressure
Study 11384023 — Surrogate Endpoint (SUR): Blood pressure
Study 28005247 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26227087 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26227087 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26227087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26227087 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19657998 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 9610957 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9610957 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7527105 — Surrogate Endpoint (SUR): Blood pressure
Study 21485024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16818663 — Predictive Biomarker (PRD): CD58 mRNA
Genes: CD58; LFA3
Study 16818663 — Predictive Biomarker (PRD): FCER1A mRNA
Genes: FCER1A; FCE1A
Study 16818663 — Predictive Biomarker (PRD): NFATC4 mRNA
Genes: NFATC4; NFAT3
Study 16818663 — Predictive Biomarker (PRD): NFRKB mRNA
Genes: NFRKB; INO80G
Study 16818663 — Safety Biomarker (SAF): Inhibin beta B chain
Genes: INHBB
Study 16818663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14521653 — Predictive Biomarker (PRD): KCNQ1 mRNA
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study 6380856 — Surrogate Endpoint (SUR): Blood pressure
Study 24716713 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22933567 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30624373 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 30624373 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23403474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8359644 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 30866027 — Surrogate Endpoint (SUR): Blood pressure
Study 29678193 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 24956865 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 8604657 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 26906014 — Surrogate Endpoint (SUR): Serum creatinine
Study 18455211 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 11022053 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31537812 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 31537812 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27739230 — Monitoring Biomarker (MOI): HBV DNA
Study 21764706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21764706 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 18385744 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 18385744 — Surrogate Endpoint (SUR): Blood pressure
Study 8762212 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8762212 — Surrogate Endpoint (SUR): Blood pressure
Study 8762212 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8762212 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22321325 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15598475 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21278424 — Monitoring Biomarker (MOI): Procalcitonin
Study 21278424 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9130032 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19023429 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 2876745 — Surrogate Endpoint (SUR): Blood pressure
Study 29313746 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24122760 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22514150 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22514150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18403272 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 26729277 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22851577 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 11879715 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11879715 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7575120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19279300 — Surrogate Endpoint (SUR): Serum calcium
Study 17250692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7521090 — Surrogate Endpoint (SUR): Blood pressure
Study 29664896 — Surrogate Endpoint (SUR): Blood pressure
Study 21051493 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9627304 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 14641260 — Surrogate Endpoint (SUR): Blood pressure
Study 8184807 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28742880 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21710615 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 14764230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14764230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31241519 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26260043 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study 19921355 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9672165 — Monitoring Biomarker (MOI): HBV DNA
Study 7729237 — Surrogate Endpoint (SUR): Blood pressure
Study 15230999 — Surrogate Endpoint (SUR): Bone mineral density
Study 8392903 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30807663 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 22177371 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27498098 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 23848972 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 23848972 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20121889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20121889 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20121889 — Surrogate Endpoint (SUR): Serum creatinine
Study 20121889 — Surrogate Endpoint (SUR): Blood pressure
Study 6333182 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31132578 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 29045997 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 29045997 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 25973934 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 22841452 — Surrogate Endpoint (SUR): Blood pressure
Study 7816383 — Safety Biomarker (SAF): 51Cr-EDTA
Study 30119757 — Surrogate Endpoint (SUR): Blood pressure
Study 24384584 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8365829 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31833849 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31833849 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31002213 — Surrogate Endpoint (SUR): Serum calcium
Study 16290015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16290015 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 16290015 — Safety Biomarker (SAF): Interleukin 1
Study 16290015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16290015 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15636308 — Surrogate Endpoint (SUR): Blood pressure
Study 15636308 — Surrogate Endpoint (SUR): Serum creatinine