TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21679006 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31432072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22910291 — Predictive Biomarker (PRD): DYSF mRNA
Genes: DYSF; FER1L1
Study 11793169 — Surrogate Endpoint (SUR): Bone mineral density
Study 10833286 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 10833286 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31146440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 28103811 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 15526839 — Surrogate Endpoint (SUR): Bone mineral density
Study 15526839 — Surrogate Endpoint (SUR): Serum calcium
Study 15526839 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 20384968 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 18534364 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 16355614 — Surrogate Endpoint (SUR): Blood pressure
Study 16355614 — Surrogate Endpoint (SUR): Serum creatinine
Study 11374327 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 3590300 — Surrogate Endpoint (SUR): Serum creatinine
Study 17009541 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 15297084 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15297084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9066384 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 25514459 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25514459 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18469252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11130522 — Surrogate Endpoint (SUR): Blood pressure
Study 11130522 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30507227 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17890873 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 11979067 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 11979067 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 23472458 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 17267326 — Surrogate Endpoint (SUR): Bone mineral density
Study 15310086 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15310086 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 2528841 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 756476 — Surrogate Endpoint (SUR): Serum triglycerides
Study 756476 — Surrogate Endpoint (SUR): Blood pressure
Study 21450580 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 21450580 — Surrogate Endpoint (SUR): Blood pressure
Study 18488201 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 12574201 — Predictive Biomarker (PRD): CASR mRNA
Genes: CASR; GPRC2A; PCAR1
Study 12574201 — Surrogate Endpoint (SUR): Bone mineral density
Study 6405607 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31651324 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19118301 — Surrogate Endpoint (SUR): Serum creatinine
Study 19498345 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30552275 — Surrogate Endpoint (SUR): Blood pressure
Study 26222203 — Predictive Biomarker (PRD): ABCA3 mRNA
Genes: ABCA3; ABC3
Study 16026368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31851799 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 28692122 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 26837842 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 26837842 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 22197578 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27840383 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27840383 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20926967 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15289793 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 11410117 — Surrogate Endpoint (SUR): Blood pressure
Study 11731182 — Surrogate Endpoint (SUR): Bone mineral density
Study 28462577 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28462577 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 17603048 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17115902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17115902 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7417369 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 31226660 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31226660 — Pharmacodynamic Biomarker (PDY): GATA-type zinc finger protein 1
Genes: ZGLP1; GLP1
Study 31226660 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26859547 — Surrogate Endpoint (SUR): Blood pressure
Study 25305352 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 25305352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 25305352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17012110 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17012110 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10981170 — Surrogate Endpoint (SUR): Blood pressure
Study 22936658 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12848631 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8963958 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8963958 — Surrogate Endpoint (SUR): Blood pressure
Study 12601506 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10365576 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 8660081 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1826048 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 16029995 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16029995 — Surrogate Endpoint (SUR): Blood pressure
Study 28807667 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 28807667 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 28807667 — Predictive Biomarker (PRD): PLIN2 mRNA
Genes: PLIN2; ADFP
Study 10938492 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10938492 — Surrogate Endpoint (SUR): Blood pressure
Study 8737690 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8737690 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1559860 — Surrogate Endpoint (SUR): Blood pressure
Study 29035099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29035099 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24509273 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 24509273 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19960343 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study 7385085 — Surrogate Endpoint (SUR): Blood pressure
Study 28287024 — Predictive Biomarker (PRD): FNDC5 mRNA
Genes: FNDC5; FRCP2
Study 22070180 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22070180 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 31136582 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28230784 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28230784 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23667649 — Surrogate Endpoint (SUR): Blood pressure
Study 17512355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17512355 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15161680 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15161680 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9495264 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 31791665 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 21045724 — Surrogate Endpoint (SUR): Blood pressure
Study 11261828 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11261828 — Surrogate Endpoint (SUR): Bone mineral density
Study 30360969 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 30360969 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 30360969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27544583 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27544583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27544583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24374088 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 18571267 — Surrogate Endpoint (SUR): Blood pressure
Study 8067226 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 30608613 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 16448970 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11709454 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 27482615 — Surrogate Endpoint (SUR): Bone mineral density
Study 27482615 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 401690 — Surrogate Endpoint (SUR): Blood pressure
Study 22010915 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10863856 — Monitoring Biomarker (MOI): HBV DNA
Study 9197874 — Surrogate Endpoint (SUR): Bone mineral density
Study 3547757 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26409014 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 12921333 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29248433 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22574741 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 9313245 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8365305 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 16120137 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11564390 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11564390 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 26479510 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 10337859 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10337859 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10337859 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22040521 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 22040521 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22040521 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 17449576 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 31136549 — Surrogate Endpoint (SUR): Blood pressure
Study 11446878 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 365428 — Surrogate Endpoint (SUR): Blood pressure
Study 28029362 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 26157049 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11845604 — Surrogate Endpoint (SUR): Blood pressure
Study 11767208 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11767208 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11767208 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 8117360 — Surrogate Endpoint (SUR): Blood pressure
Study 29999194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23611095 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2560555 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2560555 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9743818 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 30910489 — Safety Biomarker (SAF): Hyaluronic acid
Study 18422164 — Surrogate Endpoint (SUR): Serum calcium
Study 11185633 — Surrogate Endpoint (SUR): Blood pressure
Study 18633764 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18633764 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 18633764 — Surrogate Endpoint (SUR): Blood pressure
Study 11829851 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 31414632 — Predictive Biomarker (PRD): ST7 mRNA
Genes: ST7; FAM4A1; HELG; RAY1
Study 27137716 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 11060830 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22337508 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 15934094 — Surrogate Endpoint (SUR): Serum uric acid
Study 30630772 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29214526 — Surrogate Endpoint (SUR): Blood pressure
Study 29214526 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9684781 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24615085 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23545707 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 23545707 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 21715124 — Surrogate Endpoint (SUR): Blood pressure
Study 9790393 — Surrogate Endpoint (SUR): Blood pressure
Study 8543750 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29676140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29676140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18250349 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29500585 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 17663610 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 16194202 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11807406 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 10725989 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 19631774 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 30027292 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 7933639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7933639 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25872769 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25387601 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21292635 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 16155359 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30467742 — Safety Biomarker (SAF): Bacterial beta-glucuronidase
Genes: uidA; gurA; gusA; b1617; JW1609
Study 28820468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24367864 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10751104 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 9156531 — Surrogate Endpoint (SUR): Blood pressure
Study 9156531 — Surrogate Endpoint (SUR): Serum potassium
Study 27923550 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 23998158 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 9881990 — Surrogate Endpoint (SUR): Blood pressure
Study 29661156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29661156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29661156 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 13677579 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2043220 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31862195 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 19088168 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19088168 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1419813 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31188268 — Predictive Biomarker (PRD): HCN2 mRNA
Genes: HCN2; BCNG2
Study 26501464 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26501464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26501464 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26501464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20200239 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15696331 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 10205352 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28452904 — Predictive Biomarker (PRD): LGALSL mRNA
Genes: LGALSL; GRP; HSPC159
Study 10574419 — Surrogate Endpoint (SUR): Blood pressure
Study 24926075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24926075 — Surrogate Endpoint (SUR): Bone mineral density
Study 12689686 — Surrogate Endpoint (SUR): Bone mineral density
Study 12442030 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1954661 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 28532408 — Surrogate Endpoint (SUR): Bone mineral density
Study 25398399 — Surrogate Endpoint (SUR): Blood pressure
Study 21219551 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7970505 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29096949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29096949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11019429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1584317 — Surrogate Endpoint (SUR): Serum calcium
Study 23620494 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 20607877 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 15558237 — Surrogate Endpoint (SUR): Bone mineral density
Study 8664173 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8023964 — Surrogate Endpoint (SUR): Blood pressure
Study 29241306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29241306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29241306 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 29241306 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23246389 — Surrogate Endpoint (SUR): Blood pressure
Study 23246389 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12767083 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8668877 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 1510170 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29087231 — Surrogate Endpoint (SUR): Blood pressure
Study 22123358 — Surrogate Endpoint (SUR): Serum sodium
Study 22123358 — Surrogate Endpoint (SUR): Serum potassium
Study 22123358 — Surrogate Endpoint (SUR): Blood pressure
Study 22123358 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31042402 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31042402 — Surrogate Endpoint (SUR): Blood pressure
Study 25881226 — Surrogate Endpoint (SUR): Blood pressure
Study 23703604 — Surrogate Endpoint (SUR): Blood pressure
Study 15459593 — Surrogate Endpoint (SUR): Blood pressure
Study 15459593 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11263782 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 11263782 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 26811178 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 26811178 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 18245547 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18245547 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22170010 — Surrogate Endpoint (SUR): Blood pressure
Study 27725233 — Safety Biomarker (SAF): Hyaluronic acid
Study 9557932 — Surrogate Endpoint (SUR): Serum creatinine
Study 9557932 — Surrogate Endpoint (SUR): Blood pressure
Study 3071461 — Surrogate Endpoint (SUR): Blood pressure
Study 22092997 — Predictive Biomarker (PRD): FECH mRNA
Genes: FECH
Study 22092997 — Safety Biomarker (SAF): Reactive oxygen species
Study 21164127 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17163254 — Surrogate Endpoint (SUR): Serum calcium
Study 17163254 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase