TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01697904 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study NCT00841672 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00683813 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03012321 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03012321 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03012321 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study NCT03012321 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT03012321 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study NCT03012321 — Predictive Biomarker (PRD): NBN mRNA
Genes: NBN; NBS; NBS1; P95
Study NCT03012321 — Predictive Biomarker (PRD): MLH3 mRNA
Genes: MLH3
Study NCT03012321 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study NCT03012321 — Predictive Biomarker (PRD): GEN1 mRNA
Genes: GEN1
Study NCT03012321 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT00105456 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00583752 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT03892057 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02896881 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT01200407 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04113733 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study NCT04113733 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study NCT00467194 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00025207 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00025207 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03196180 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT02886949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02886949 — Safety Biomarker (SAF): BDNF
Study NCT03556345 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03878290 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03779334 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT00233207 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT04547101 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT03750175 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03750175 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00871455 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT04425200 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04425200 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT01730118 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00312871 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04785742 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04212559 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04371471 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00516061 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00516061 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02449993 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02449993 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02449993 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT01796210 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03785210 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04098393 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04265742 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03915951 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 31266030 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 25924549 — Surrogate Endpoint (SUR): Serum creatinine
Study 9124477 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 8312826 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25864279 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 25864279 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 21347782 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 19858812 — Surrogate Endpoint (SUR): Blood pressure
Study 10537439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22943949 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25703961 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 14749208 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 14749208 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 9071101 — Surrogate Endpoint (SUR): Blood pressure
Study 27774726 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22382203 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22382203 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 15632893 — Predictive Biomarker (PRD): SAGE1 mRNA
Genes: SAGE1; SAGE
Study 15632893 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3266276 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 30273282 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 25177815 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6432374 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 6432374 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29770541 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10584839 — Surrogate Endpoint (SUR): Serum sodium
Study 10584839 — Surrogate Endpoint (SUR): Serum potassium
Study 1871175 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 29987324 — Surrogate Endpoint (SUR): Blood pressure
Study 12466788 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 7855555 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29239901 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27981743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24024321 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 18192843 — Surrogate Endpoint (SUR): Blood pressure
Study 8621136 — Surrogate Endpoint (SUR): Serum creatinine
Study 1417188 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1417188 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3899841 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20213467 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20213467 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16521847 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30739369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24835171 — Predictive Biomarker (PRD): SLC12A5 mRNA
Genes: SLC12A5; KCC2; KIAA1176
Study 24835171 — Predictive Biomarker (PRD): SLC12A2 mRNA
Genes: SLC12A2; NKCC1
Study 20199828 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15670038 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 26512775 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19375907 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 3663580 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11942448 — Surrogate Endpoint (SUR): Blood pressure
Study 2517696 — Surrogate Endpoint (SUR): Bone mineral density
Study 18664347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15856479 — Surrogate Endpoint (SUR): Serum creatinine
Study 19463506 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19463506 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 19463506 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 19463506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17763588 — Surrogate Endpoint (SUR): Blood pressure
Study 9602585 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7472698 — Surrogate Endpoint (SUR): Blood pressure
Study 18005908 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21692822 — Monitoring Biomarker (MOI): HBV DNA
Study 20045801 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16421680 — Surrogate Endpoint (SUR): Blood pressure
Study 11734515 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19654233 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 9487787 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29511130 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18725489 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26775606 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 26775606 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 26775606 — Predictive Biomarker (PRD): CCL24 mRNA
Genes: CCL24; MPIF2; SCYA24
Study 26775606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12909491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19744406 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19744406 — Safety Biomarker (SAF): BDNF
Study 16777915 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15743112 — Safety Biomarker (SAF): Reactive oxygen species
Study 3490334 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 3490334 — Surrogate Endpoint (SUR): Blood pressure
Study 30721586 — Surrogate Endpoint (SUR): Serum sodium
Study 23017355 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 23017355 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31594895 — Surrogate Endpoint (SUR): Blood pressure
Study 27480291 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 27480291 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 30376108 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21075600 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 17531577 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15356085 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8162994 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25444990 — Surrogate Endpoint (SUR): Blood pressure
Study 19571570 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 11049837 — Surrogate Endpoint (SUR): Blood pressure
Study 30753371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19531899 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11328905 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11328905 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3802437 — Surrogate Endpoint (SUR): Blood pressure
Study 21083721 — Surrogate Endpoint (SUR): Blood pressure
Study 7801420 — Surrogate Endpoint (SUR): Blood pressure
Study 29667290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11305509 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 10150183 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31706292 — Predictive Biomarker (PRD): DEFA1 mRNA
Genes: DEFA1; DEF1; DEFA2; MRS; DEFA1B
Study 28531241 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23634822 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1492432 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 14501606 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14501606 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14501606 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14501606 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14501606 — Surrogate Endpoint (SUR): Blood pressure
Study 16831981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16831981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16831981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16831981 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12624579 — Surrogate Endpoint (SUR): Blood pressure
Study 21552645 — Surrogate Endpoint (SUR): Blood pressure
Study 18471515 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10947689 — Surrogate Endpoint (SUR): Blood pressure
Study 16025045 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 10585359 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 3653766 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 21266792 — Predictive Biomarker (PRD): LYN mRNA
Genes: LYN; JTK8
Study 19453719 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 22087865 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22087865 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10767716 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31731651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31731651 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22100194 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6786134 — Surrogate Endpoint (SUR): Blood pressure
Study 28704258 — Surrogate Endpoint (SUR): Blood pressure
Study 30704700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28103612 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21953143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21953143 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 21953143 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 21953143 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 3003728 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30927744 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 23398528 — Surrogate Endpoint (SUR): Blood pressure
Study 30905021 — Predictive Biomarker (PRD): Anti-acetylcholine receptor antibody
Study 28963592 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28963592 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28963592 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28963592 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16980747 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 15531693 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24868083 — Surrogate Endpoint (SUR): Blood pressure
Study 24868083 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15969661 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 23254273 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 10084579 — Predictive Biomarker (PRD): CYP21A2 mRNA
Genes: CYP21A2; CYP21; CYP21B
Study 29702271 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 26094656 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 10355660 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 2018005 — Surrogate Endpoint (SUR): Blood pressure
Study 23463811 — Surrogate Endpoint (SUR): Blood pressure
Study 19125264 — Surrogate Endpoint (SUR): Blood pressure
Study 19125264 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19125264 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11472741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11472741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11472741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11472741 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9602957 — Surrogate Endpoint (SUR): Serum uric acid
Study 20067964 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 14578240 — Surrogate Endpoint (SUR): Blood pressure
Study 11113723 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8210967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11828239 — Surrogate Endpoint (SUR): Bone mineral density
Study 25141084 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 22040002 — Surrogate Endpoint (SUR): Bone mineral density
Study 2213104 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22422824 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19675321 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8818207 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18777490 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2031502 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 2031502 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 19497461 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19497461 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 15763450 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 30138239 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24080993 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 30767788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30767788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10321444 — Surrogate Endpoint (SUR): Blood pressure
Study 21091100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15144908 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11977322 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 11977322 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9701895 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 9701895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2528983 — Surrogate Endpoint (SUR): Blood pressure
Study 19429721 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8750275 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study 27663365 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 27663365 — Surrogate Endpoint (SUR): Serum creatinine
Study 24785761 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 12406021 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 2139175 — Surrogate Endpoint (SUR): Blood pressure
Study 17324285 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15220185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12457389 — Predictive Biomarker (PRD): FURIN mRNA
Genes: FURIN; FUR; PACE; PCSK3
Study 10413652 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10413652 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29512121 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 29512121 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 21309476 — Surrogate Endpoint (SUR): Blood pressure
Study 12088304 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31950604 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28283797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 28283797 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 21681118 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10858346 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 10858346 — Predictive Biomarker (PRD): IRF1 mRNA
Genes: IRF1
Study 10858346 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 10858346 — Predictive Biomarker (PRD): IRF2 mRNA
Genes: IRF2
Study 10858346 — Predictive Biomarker (PRD): PIAS1 mRNA
Genes: PIAS1; DDXBP1
Study 9200356 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29733995 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 16356358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16356358 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16356358 — Surrogate Endpoint (SUR): Blood pressure
Study 8346593 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8346593 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 8346593 — Surrogate Endpoint (SUR): Blood pressure
Study 27513312 — Surrogate Endpoint (SUR): Blood pressure
Study 27513312 — Surrogate Endpoint (SUR): Serum creatinine
Study 20920126 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16116958 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 24240575 — Surrogate Endpoint (SUR): Serum calcium
Study 18302711 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4