TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19930904 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19930904 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 19930904 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19930904 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12684572 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 8910181 — Surrogate Endpoint (SUR): Blood pressure
Study 15257046 — Surrogate Endpoint (SUR): Bone mineral density
Study 9525435 — Surrogate Endpoint (SUR): Serum creatinine
Study 7893034 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25583753 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 29343507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25910532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25607594 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20549321 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17448266 — Surrogate Endpoint (SUR): Bone mineral density
Study 17448266 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14983226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 14983226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2455176 — Surrogate Endpoint (SUR): Blood pressure
Study 27956428 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 19573486 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9258754 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 9258754 — Surrogate Endpoint (SUR): Bone mineral density
Study 20233517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30571495 — Surrogate Endpoint (SUR): Blood pressure
Study 24302608 — Surrogate Endpoint (SUR): Serum calcium
Study 17478939 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 30971235 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 24103901 — Surrogate Endpoint (SUR): Blood pressure
Study 2291838 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6796885 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27930939 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27062157 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27537244 — Safety Biomarker (SAF): IL-6 and IL-10
Study 18980622 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 2660319 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19701463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19701463 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8443029 — Surrogate Endpoint (SUR): Blood pressure
Study 31125092 — Surrogate Endpoint (SUR): Bone mineral density
Study 18834718 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18834718 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25073833 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 19841043 — Surrogate Endpoint (SUR): Bone mineral density
Study 14740153 — Surrogate Endpoint (SUR): Bone mineral density
Study 10936784 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 10936784 — Predictive Biomarker (PRD): ALPP mRNA
Genes: ALPP; PLAP
Study 22816729 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19710003 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26389600 — Predictive Biomarker (PRD): CNDP1 mRNA
Genes: CNDP1; CN1; CPGL2; UNQ1915/PRO4380
Study 23216584 — Surrogate Endpoint (SUR): Blood pressure
Study 23216584 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 17943480 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study 8082533 — Surrogate Endpoint (SUR): Blood pressure
Study 2563239 — Surrogate Endpoint (SUR): Blood pressure
Study 31574964 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31574964 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31574964 — Surrogate Endpoint (SUR): Blood pressure
Study 24595862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21871931 — Surrogate Endpoint (SUR): Blood pressure
Study 15294086 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31894446 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 26766737 — Surrogate Endpoint (SUR): Blood pressure
Study 15701209 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15701209 — Surrogate Endpoint (SUR): Serum creatinine
Study 23940461 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16860190 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16860190 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3033968 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24297796 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10934081 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31203685 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29672196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29672196 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 29672196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12826215 — Surrogate Endpoint (SUR): Serum creatinine
Study 10499601 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 10499601 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19512949 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22154367 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22154367 — Surrogate Endpoint (SUR): Blood pressure
Study 30027313 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1908138 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 23739317 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15888064 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 7611207 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7843749 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 7843749 — Surrogate Endpoint (SUR): Blood pressure
Study 2236726 — Surrogate Endpoint (SUR): Serum creatinine
Study 29545948 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 19910943 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15708100 — Surrogate Endpoint (SUR): Serum creatinine
Study 12372942 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12372942 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12372942 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 25849646 — Surrogate Endpoint (SUR): Blood pressure
Study 17498002 — Surrogate Endpoint (SUR): Serum calcium
Study 11166966 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 9539899 — Surrogate Endpoint (SUR): Blood pressure
Study 9539899 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9539899 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30075760 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18555912 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17360900 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 9753210 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19957874 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11331953 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 9173967 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7930246 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2856053 — Surrogate Endpoint (SUR): Blood pressure
Study 31158346 — Surrogate Endpoint (SUR): Blood pressure
Study 22773108 — Surrogate Endpoint (SUR): Bone mineral density
Study 15949728 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 15949728 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31091064 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30030584 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 12015785 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study 28276638 — Surrogate Endpoint (SUR): Bone mineral density
Study 27669539 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15767218 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 12410497 — Surrogate Endpoint (SUR): Serum creatinine
Study 1741534 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24616624 — Surrogate Endpoint (SUR): Blood pressure
Study 19439741 — Predictive Biomarker (PRD): Hormone receptor
Study 18026240 — Safety Biomarker (SAF): Hyaluronic acid
Study 11133852 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 3046629 — Surrogate Endpoint (SUR): Blood pressure
Study 20642548 — Surrogate Endpoint (SUR): Serum uric acid
Study 17667643 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17667643 — Surrogate Endpoint (SUR): Blood pressure
Study 2263931 — Surrogate Endpoint (SUR): Blood pressure
Study 12164890 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 365797 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31670004 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28480505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28480505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28480505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28480505 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21189395 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21189395 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 18548143 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18548143 — Surrogate Endpoint (SUR): Blood pressure
Study 16781245 — Surrogate Endpoint (SUR): Blood pressure
Study 10860407 — Surrogate Endpoint (SUR): Blood pressure
Study 25509730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25509730 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 25509730 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 12867608 — Predictive Biomarker (PRD): Microsatellite instability
Study 1704985 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1704985 — Surrogate Endpoint (SUR): Blood pressure
Study 30701292 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23953493 — Surrogate Endpoint (SUR): Blood pressure
Study 17287150 — Surrogate Endpoint (SUR): Blood pressure
Study 9377657 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2970853 — Surrogate Endpoint (SUR): Blood pressure
Study 28270187 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28270187 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 28270187 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28270187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28270187 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study 12697866 — Predictive Biomarker (PRD): FGF7 mRNA
Genes: FGF7; KGF
Study 6504920 — Surrogate Endpoint (SUR): Plasma ammonia
Study 6504920 — Surrogate Endpoint (SUR): Serum testosterone
Study 17590217 — Surrogate Endpoint (SUR): Blood pressure
Study 12357730 — Surrogate Endpoint (SUR): Bone mineral density
Study 12357730 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26283175 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10871979 — Surrogate Endpoint (SUR): Blood pressure
Study 10871979 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24904785 — Surrogate Endpoint (SUR): Blood pressure
Study 20147743 — Predictive Biomarker (PRD): FGFR4 mRNA
Genes: FGFR4; JTK2; TKF
Study 12461659 — Surrogate Endpoint (SUR): Serum creatinine
Study 8822109 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30669360 — Predictive Biomarker (PRD): JUN mRNA
Genes: JUN
Study 30669360 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 21289621 — Predictive Biomarker (PRD): KCNQ1 mRNA
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study 16849623 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 29198641 — Surrogate Endpoint (SUR): Serum potassium
Study 23578719 — Surrogate Endpoint (SUR): Bone mineral density
Study 12853193 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11173778 — Surrogate Endpoint (SUR): Blood pressure
Study 6828338 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30115454 — Predictive Biomarker (PRD): Hormone receptor
Study 24463933 — Surrogate Endpoint (SUR): Blood pressure
Study 19158191 — Surrogate Endpoint (SUR): Blood pressure
Study 17229249 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17229249 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28301428 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 24325112 — Surrogate Endpoint (SUR): Blood pressure
Study 22136978 — Surrogate Endpoint (SUR): Blood pressure
Study 15277147 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7862856 — Surrogate Endpoint (SUR): Blood pressure
Study 25487613 — Surrogate Endpoint (SUR): Blood pressure
Study 23594436 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23594436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23594436 — Surrogate Endpoint (SUR): Blood pressure
Study 15086616 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26297368 — Surrogate Endpoint (SUR): Bone mineral density
Study 21241489 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 21241489 — Predictive Biomarker (PRD): PPIC mRNA
Genes: PPIC; CYPC
Study 21241489 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12691509 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2866558 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31070229 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 22693121 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 22693121 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12085364 — Monitoring Biomarker (MOI): HBV DNA
Study 9468078 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2505716 — Surrogate Endpoint (SUR): Serum creatinine
Study 31043657 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 21389149 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 17290043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23091142 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 23091142 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19667110 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 19667110 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10444645 — Surrogate Endpoint (SUR): Blood pressure
Study 23433279 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 11696805 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9137792 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7970538 — Safety Biomarker (SAF): Hyaluronic acid
Study 21136299 — Predictive Biomarker (PRD): OSR1 mRNA
Genes: OSR1; ODD
Study 9286888 — Surrogate Endpoint (SUR): Blood pressure
Study 24635387 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 24635387 — Surrogate Endpoint (SUR): Blood pressure
Study 20668035 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 9641612 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 9641612 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 9641612 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 979068 — Surrogate Endpoint (SUR): Serum potassium
Study 31070869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31070869 — Predictive Biomarker (PRD): IL17F
Genes: IL-17F; ML-1; ML1
Study 24557584 — Surrogate Endpoint (SUR): Blood pressure
Study 16364555 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15291656 — Predictive Biomarker (PRD): MARCKS mRNA
Genes: MARCKS; MACS; PRKCSL
Study 15291656 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 11115082 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11115082 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11115082 — Surrogate Endpoint (SUR): Serum creatinine
Study 11115082 — Safety Biomarker (SAF): Urinary total protein
Study 1361311 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1361311 — Surrogate Endpoint (SUR): Blood pressure
Study 26023230 — Surrogate Endpoint (SUR): Blood pressure
Study 16699858 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1482251 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 1482251 — Surrogate Endpoint (SUR): Blood pressure
Study 6094103 — Surrogate Endpoint (SUR): Serum triglycerides
Study 3884691 — Surrogate Endpoint (SUR): Blood pressure
Study 20501356 — Surrogate Endpoint (SUR): Bone mineral density
Study 31832001 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 31832001 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 31832001 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23936148 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31778222 — Surrogate Endpoint (SUR): Blood pressure
Study 3318454 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3318454 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30333494 — Predictive Biomarker (PRD): SPINK1 mRNA
Genes: SPINK1; PSTI
Study 30333494 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20419161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20419161 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17311303 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17311303 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 11374852 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8795482 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7745993 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23644384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23644384 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 23644384 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11699405 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 8281674 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22718435 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 16540931 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3977547 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30959858 — Surrogate Endpoint (SUR): Blood pressure
Study 9032191 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 3111784 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31856379 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31135272 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 11515715 — Surrogate Endpoint (SUR): Blood pressure
Study 31841279 — Surrogate Endpoint (SUR): Blood pressure
Study 28293063 — Safety Biomarker (SAF): miR-200c
Genes: MIR200C
Study 11371420 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 2967186 — Surrogate Endpoint (SUR): Blood pressure
Study 29682796 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24477179 — Surrogate Endpoint (SUR): Blood pressure
Study 12360164 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7482063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30934166 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 29779795 — Surrogate Endpoint (SUR): Blood pressure
Study 22778174 — Surrogate Endpoint (SUR): Blood pressure
Study 21740986 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 21740986 — Safety Biomarker (SAF): Reactive oxygen species
Study 14506950 — Surrogate Endpoint (SUR): Bone mineral density
Study 31551368 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25606700 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22942727 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31391011 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 17139244 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF