TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22073889 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22073889 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22073889 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 22073889 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 22073889 — Surrogate Endpoint (SUR): Blood pressure
Study 27509141 — Surrogate Endpoint (SUR): Blood pressure
Study 14568963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14568963 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23261172 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 17582922 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 15044114 — Safety Biomarker (SAF): MTHFR
Study 8597984 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 2527536 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15153170 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15153170 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23152584 — Predictive Biomarker (PRD): CLCN1 mRNA
Genes: CLCN1; CLC1
Study 18614347 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16371154 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 16371154 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12460041 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 1423955 — Surrogate Endpoint (SUR): Blood pressure
Study 26550945 — Surrogate Endpoint (SUR): Blood pressure
Study 15212190 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 24980238 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 24980238 — Predictive Biomarker (PRD): IFT122 mRNA
Genes: IFT122; SPG; WDR10; WDR140
Study 23756400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20653494 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 18408938 — Surrogate Endpoint (SUR): Blood pressure
Study 9361692 — Surrogate Endpoint (SUR): Blood pressure
Study 24856872 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 24856872 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20963833 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 19549432 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11568516 — Predictive Biomarker (PRD): HLF mRNA
Genes: HLF
Study 24980710 — Monitoring Biomarker (MOI): HBV DNA
Study 12783043 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 24716412 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11705489 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 11705489 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 21545273 — Surrogate Endpoint (SUR): Blood pressure
Study 21545273 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11583471 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 2643751 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25929392 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 9234826 — Surrogate Endpoint (SUR): Blood pressure
Study 30318837 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16291412 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16291412 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 12145231 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 10211849 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 7614527 — Surrogate Endpoint (SUR): Blood pressure
Study 26220326 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 17366867 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11108723 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6240210 — Surrogate Endpoint (SUR): Blood pressure
Study 26823689 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 26823689 — Surrogate Endpoint (SUR): Blood pressure
Study 7632972 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2713221 — Surrogate Endpoint (SUR): Blood pressure
Study 26797499 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16463664 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 16463664 — Surrogate Endpoint (SUR): Bone mineral density
Study 12898884 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 12898884 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 31151464 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 21296446 — Surrogate Endpoint (SUR): Blood pressure
Study 11467142 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 2848604 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2848604 — Surrogate Endpoint (SUR): Blood pressure
Study 30251879 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 15746991 — Surrogate Endpoint (SUR): Blood pressure
Study 11955844 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10206072 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10206072 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17968434 — Surrogate Endpoint (SUR): Blood pressure
Study 9738560 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2975612 — Surrogate Endpoint (SUR): Blood pressure
Study 21474134 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 18341663 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 9085405 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9085405 — Predictive Biomarker (PRD): PTK7 mRNA
Genes: PTK7; CCK4
Study 18829518 — Surrogate Endpoint (SUR): Bone mineral density
Study 19552838 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19552838 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14743850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14743850 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9476036 — Surrogate Endpoint (SUR): Blood pressure
Study 27019267 — Surrogate Endpoint (SUR): Blood pressure
Study 10217339 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10217339 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 24426779 — Surrogate Endpoint (SUR): Bone mineral density
Study 3275684 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 31444252 — Surrogate Endpoint (SUR): Serum asparaginase
Study 28425272 — Surrogate Endpoint (SUR): Serum potassium
Study 11325669 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11325669 — Surrogate Endpoint (SUR): Blood pressure
Study 9934406 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 19490477 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19490477 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 19490477 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 9102064 — Surrogate Endpoint (SUR): Bone mineral density
Study 29128898 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24337734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1671875 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 16396651 — Surrogate Endpoint (SUR): Blood pressure
Study 8027273 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7342 — Surrogate Endpoint (SUR): Blood pressure
Study 31885153 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 31885153 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 31621256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31621256 — Monitoring Biomarker (MOI): Procalcitonin
Study 31621256 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25742762 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23817699 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20215537 — Predictive Biomarker (PRD): Hormone receptor
Study 20215537 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16754711 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 16754711 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 31441999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10049657 — Surrogate Endpoint (SUR): Blood pressure
Study 8523926 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31322918 — Surrogate Endpoint (SUR): Bone mineral density
Study 21342170 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11451781 — Surrogate Endpoint (SUR): Blood pressure
Study 11451781 — Surrogate Endpoint (SUR): Serum creatinine
Study 26861113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 10671945 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 25277334 — Surrogate Endpoint (SUR): Serum creatinine
Study 15145973 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11920261 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 31740463 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 22248871 — Surrogate Endpoint (SUR): Blood pressure
Study 15687112 — Surrogate Endpoint (SUR): Serum potassium
Study 10086794 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10086794 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27673483 — Safety Biomarker (SAF): Hyaluronic acid
Study 15008996 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15008996 — Surrogate Endpoint (SUR): Blood pressure
Study 26057917 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24152688 — Surrogate Endpoint (SUR): Serum testosterone
Study 24152688 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24152688 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28337876 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23052033 — Surrogate Endpoint (SUR): Blood pressure
Study 22073219 — Surrogate Endpoint (SUR): Blood pressure
Study 16446752 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10694768 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24628464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22031515 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20696074 — Predictive Biomarker (PRD): FTL mRNA
Genes: FTL
Study 3109142 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25179788 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25179788 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10634964 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31426749 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26402762 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24088280 — Surrogate Endpoint (SUR): Blood pressure
Study 19626385 — Predictive Biomarker (PRD): TCP1 mRNA
Genes: TCP1; CCT1; CCTA
Study 10352494 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7655780 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28467116 — Surrogate Endpoint (SUR): Blood pressure
Study 25599690 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25599690 — Surrogate Endpoint (SUR): Blood pressure
Study 18216051 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14690014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10378072 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26931369 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26931369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26931369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20235638 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9366459 — Surrogate Endpoint (SUR): Blood pressure
Study 1286492 — Surrogate Endpoint (SUR): Blood pressure
Study 15075543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31353231 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31353231 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26011261 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 26011261 — Predictive Biomarker (PRD): SUB1 mRNA
Genes: SUB1; PC4; RPO2TC1
Study 29570164 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 24811615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24811615 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16143248 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 16143248 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12756512 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 8595083 — Surrogate Endpoint (SUR): Blood pressure
Study 1709446 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1709446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11268266 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11268266 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2567793 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 107583 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 18668363 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18668363 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18668363 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 18668363 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ESR1 mRNA
Genes: ESR1; ESR; NR3A1
Study 14989560 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10752807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10752807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10752807 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 10752807 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 14681342 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 14681342 — Surrogate Endpoint (SUR): Blood pressure
Study 30161291 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study 30161291 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 30161291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25907945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25907945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21715516 — Safety Biomarker (SAF): Reactive oxygen species
Study 21715516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21715516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21715516 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11430324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30086484 — Surrogate Endpoint (SUR): Blood pressure
Study 30086484 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 23592533 — Surrogate Endpoint (SUR): Blood pressure
Study 17031012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31142474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31142474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23732250 — Surrogate Endpoint (SUR): Blood pressure
Study 12577417 — Surrogate Endpoint (SUR): Blood pressure
Study 23588257 — Surrogate Endpoint (SUR): Blood pressure
Study 8793702 — Surrogate Endpoint (SUR): Blood pressure
Study 18848350 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10813108 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29649992 — Surrogate Endpoint (SUR): Blood pressure
Study 27067521 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26598141 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17062301 — Surrogate Endpoint (SUR): Blood pressure
Study 10941607 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 20218813 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 2039996 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2039996 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30224345 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 26655003 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26655003 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12051574 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24927031 — Predictive Biomarker (PRD): RHOJ mRNA
Genes: RHOJ; ARHJ; RASL7B; RHOI; TCL
Study 19727679 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 7516641 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18487567 — Predictive Biomarker (PRD): Hormone receptor
Study 18487567 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29431140 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25184356 — Predictive Biomarker (PRD): NOTCH3 mRNA
Genes: NOTCH3
Study 20005545 — Safety Biomarker (SAF): Reactive oxygen species
Study 27862715 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9573749 — Surrogate Endpoint (SUR): Blood pressure
Study 8158885 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8158885 — Surrogate Endpoint (SUR): Blood pressure
Study 20143872 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 20143872 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 10808678 — Surrogate Endpoint (SUR): Bone mineral density
Study 20831697 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8196254 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26204531 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25756419 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25756419 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 25756419 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 25756419 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 25756419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25756419 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 25756419 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25756419 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 25756419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25756419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23187936 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 23187936 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19506932 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 19506932 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16284083 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9497875 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 19002337 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9817939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9817939 — Surrogate Endpoint (SUR): Bone mineral density
Study 9817939 — Safety Biomarker (SAF): Interleukin 1
Study 9817939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11809090 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11809090 — Surrogate Endpoint (SUR): Blood pressure
Study 25449505 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 23016708 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 17398308 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 8745384 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 1716979 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP