TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04035109 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study NCT04035109 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study NCT04035109 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT03363685 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03363685 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT02812641 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02812641 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02812641 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01413230 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04735042 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05687201 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT00461955 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02462421 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03730012 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04129294 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03763643 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03865134 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01351428 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02330224 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03308786 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03308786 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03571776 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01466803 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02053025 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT01980628 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00470847 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00001443 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03506061 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02350673 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02350673 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02350673 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01878617 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study NCT02939079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02939079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02939079 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02927262 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT03694912 — Predictive Biomarker (PRD): KDM5C mRNA
Genes: KDM5C; DXS1272E; JARID1C; SMCX; XE169
Study NCT03694912 — Predictive Biomarker (PRD): FOXC2 mRNA
Genes: FOXC2; FKHL14; MFH1
Study NCT03694912 — Predictive Biomarker (PRD): CLIP4 mRNA
Genes: CLIP4; RSNL2
Study NCT00799110 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02570841 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT00402142 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05019794 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT05019794 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT04330248 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00273910 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT03004443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03004443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03004443 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study NCT02637336 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04281641 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04281641 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02923466 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT00006244 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03815435 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03352505 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03352505 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03352505 — Safety Biomarker (SAF): BDNF
Study NCT00903461 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00903461 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02027376 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02027376 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01308931 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04676152 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01165996 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study NCT01365065 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02107352 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT00583232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02688803 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02688803 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04170842 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03059537 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study NCT01498328 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00114387 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01026714 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01026714 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00938652 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00938652 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT00938652 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01634763 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00932737 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study NCT04126551 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04227301 — Surrogate Endpoint (SUR): Serum sodium
Study NCT00931788 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04562493 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04460456 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03360747 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study NCT03360747 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02484690 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02484690 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02127723 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03783091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03803761 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03803761 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03803761 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04412473 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04366986 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02729155 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04156269 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT02585622 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01442649 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01442649 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01442649 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01285778 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00004381 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT02936089 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT02936089 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study NCT03412292 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study NCT01516736 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT03397121 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03397121 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00556257 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study NCT03291951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03291951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00632645 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01879839 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03882164 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00467909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03496870 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT03061578 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT02883192 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04908657 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03633409 — Predictive Biomarker (PRD): GPR183 mRNA
Genes: GPR183; EBI2
Study NCT05573438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05573438 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05573438 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05573438 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT05573438 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT05573438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05573438 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT05573438 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT05573438 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00639925 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00639925 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00639925 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT03492892 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01039974 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04396496 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT02493582 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03679195 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00356733 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02103023 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT02811757 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study NCT02997423 — Safety Biomarker (SAF): Cytochrome c
Study NCT01279473 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01279473 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02561416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02547948 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02457858 — Predictive Biomarker (PRD): BMX mRNA
Genes: BMX
Study NCT03835104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04439279 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT04439279 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study NCT00677911 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00677911 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00677911 — Safety Biomarker (SAF): Interleukin 1
Study NCT00677911 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02723994 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT02723994 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT02723994 — Predictive Biomarker (PRD): CRLF2 mRNA
Genes: CRLF2; CRL2; ILXR; TSLPR
Study NCT02051881 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT00546390 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00900601 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study NCT01282203 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00905216 — Predictive Biomarker (PRD): TTPA mRNA
Genes: TTPA; TPP1
Study NCT04121988 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00105586 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01642082 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00888797 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study NCT03819426 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00005439 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04480463 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04480463 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01840618 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03711201 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02645786 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02080858 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study NCT02080858 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02347735 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TAGLN mRNA
Genes: TAGLN; SM22; WS3-10
Study NCT02347735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02347735 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT01284582 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT01284582 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05135247 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05704010 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study NCT05704010 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT01341795 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study NCT00700024 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02688894 — Predictive Biomarker (PRD): SH3PXD2A mRNA
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study NCT03162068 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT03162068 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04190667 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04190667 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04190667 — Predictive Biomarker (PRD): ABRAXAS1 mRNA
Genes: ABRAXAS1; ABRA1; CCDC98; FAM175A; UNQ496/PRO1013
Study NCT04190667 — Predictive Biomarker (PRD): BARD1 mRNA
Genes: BARD1
Study NCT04190667 — Predictive Biomarker (PRD): C11orf30
Genes: EMSY
Study NCT04190667 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study NCT04190667 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study NCT04190667 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study NCT04190667 — Predictive Biomarker (PRD): FANCD2 mRNA
Genes: FANCD2; FACD
Study NCT04190667 — Predictive Biomarker (PRD): FANCI mRNA
Genes: FANCI; KIAA1794
Study NCT04190667 — Predictive Biomarker (PRD): FANCL mRNA
Genes: FANCL; PHF9
Study NCT04190667 — Predictive Biomarker (PRD): NBN mRNA
Genes: NBN; NBS; NBS1; P95
Study NCT04190667 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT04190667 — Predictive Biomarker (PRD): PPP2R2A mRNA
Genes: PPP2R2A
Study NCT04190667 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT04190667 — Predictive Biomarker (PRD): RAD51B mRNA
Genes: RAD51B; RAD51L1; REC2
Study NCT04190667 — Predictive Biomarker (PRD): RAD51C mRNA
Genes: RAD51C; RAD51L2
Study NCT04190667 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study NCT04190667 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT04190667 — Predictive Biomarker (PRD): EPCAM mRNA
Genes: EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Study NCT04190667 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study NCT04190667 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT04190667 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT04190667 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT04723901 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04723901 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT04573998 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03646630 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03722771 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02820584 — Predictive Biomarker (PRD): GSC mRNA
Genes: GSC
Study NCT01414426 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01414426 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01570868 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01570868 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00874432 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00874432 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00447317 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04151329 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02873026 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT04168255 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02455453 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02455453 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02698683 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01702571 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05386290 — Safety Biomarker (SAF): Interleukin 12
Study NCT04957212 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00491231 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00551044 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02785562 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00386607 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00458302 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study NCT04388124 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT02080637 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01022801 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04195529 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT02500823 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT02952729 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02067780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02949323 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT00909727 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03654378 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02035501 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study NCT05666622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02121782 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT02883166 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study NCT00492206 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00492206 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04022434 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00350701 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03605927 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5