TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00770991 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT00632034 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00632034 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00813956 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT02283320 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02061423 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03336983 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03336983 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03363893 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03363893 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03363893 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03363893 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01950936 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT04019418 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT00576693 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03280550 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00863629 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT00564291 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01016483 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study NCT02668783 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT02128828 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02128828 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT03845296 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03143374 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01674543 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01185652 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT01185652 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT01185652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00006270 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT05447026 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05447026 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05447026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00500253 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03427060 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT06022133 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00427960 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00427960 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03856996 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00377975 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study NCT01126619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01083563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05937113 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01987284 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01973543 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study NCT01662973 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01227239 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00915603 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04250493 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT04250493 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study NCT03315494 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study NCT00003962 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00800033 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00800033 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT00800033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02594540 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00134758 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT04350164 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT02496741 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT02496741 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study NCT03960554 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02122731 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03603288 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02540161 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00965510 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study NCT00048061 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03025711 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01512368 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT00003356 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01604213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01604213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01604213 — Safety Biomarker (SAF): Interleukin 1
Study NCT02264938 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02090335 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02265016 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study NCT01423071 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02819440 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT04195074 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00355589 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01775462 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study NCT04322214 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04341532 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01007890 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02414217 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00542971 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00542971 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT00542971 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00542971 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02942420 — Surrogate Endpoint (SUR): Urinary cystine
Study NCT04018144 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT04018144 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT00947856 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT01233219 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT01405976 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01753804 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01506089 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT01464723 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01464723 — Predictive Biomarker (PRD): HTRA1 mRNA
Genes: HTRA1; HTRA; PRSS11
Study NCT03546478 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03802422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04223167 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04128657 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study NCT04373980 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04425824 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00562510 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02393599 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02393599 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00991627 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02273323 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04174885 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03833596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00602862 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT00602862 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT00602862 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00602862 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT00602862 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02687321 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT04227080 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00028275 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03592693 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT00675285 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01951482 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00101127 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03250338 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01350518 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00219167 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02906371 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00172120 — Predictive Biomarker (PRD): ALX1 mRNA
Genes: ALX1; CART1
Study NCT00172120 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03815084 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00487734 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02131896 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03339882 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03339882 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04345978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04345978 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT00247910 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03939130 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03939130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03939130 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT03939130 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04351555 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04351555 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01327911 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study NCT04463121 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03952923 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03511352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study NCT03511352 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02391727 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01299597 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03602014 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00843453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00277472 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02020343 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00001444 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study NCT03031522 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00532727 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00949286 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01356953 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01709578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00891306 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT00171639 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02099266 — Predictive Biomarker (PRD): UBC mRNA
Genes: UBC
Study NCT03408600 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02454270 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01930084 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03005535 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03005535 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04333771 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT03616769 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03591705 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT03147976 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04481594 — Predictive Biomarker (PRD): HPN mRNA
Genes: HPN; TMPRSS1
Study NCT01671787 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02572206 — Predictive Biomarker (PRD): CNTNAP2 mRNA
Genes: CNTNAP2; CASPR2; KIAA0868
Study NCT01445743 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study NCT04003155 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01678937 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT03645031 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05405465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00921505 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01935102 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01935102 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study NCT01935102 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01935102 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00446589 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05340751 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04328675 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT01456546 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00209508 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study NCT04585152 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01105403 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00817674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00463489 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01541592 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03751709 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04437225 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT01198535 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03491345 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study NCT03491345 — Predictive Biomarker (PRD): POLD1 mRNA
Genes: POLD1; POLD
Study NCT03491345 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT03491345 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04292119 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04292119 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT02747043 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02747043 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT05348187 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01073592 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02493725 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT02282410 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT01463852 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study NCT04164888 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01454674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03999528 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00987987 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01832311 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01832311 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT01832311 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT01832311 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02595060 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00306436 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03634826 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04166149 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00233220 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01485783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01259297 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03333525 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study NCT02771808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02771808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00898261 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00898261 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT05253144 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT03534739 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT01538108 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT02405507 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02904421 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04237571 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00854932 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01052597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01052597 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00004865 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03865407 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02070900 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04181203 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00239200 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00239200 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01350141 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01754259 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02787369 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04510974 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04510974 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00004048 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03632512 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT03632512 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01892969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01892969 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT02807116 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04282512 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01494688 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01494688 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02171702 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02171702 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00311870 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00311870 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01368276 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03620838 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02156648 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00590681 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00590681 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02740790 — Surrogate Endpoint (SUR): Neutralizing antibody