TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28922099 — Safety Biomarker (SAF): Interleukin 1
Study 19707782 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15572850 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12087908 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 27417272 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27417272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27417272 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27417272 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27417272 — Surrogate Endpoint (SUR): Blood pressure
Study 12048134 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 12048134 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 12048134 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6118757 — Surrogate Endpoint (SUR): Blood pressure
Study 25688120 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 25248358 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25248358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25248358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15631278 — Surrogate Endpoint (SUR): Blood pressure
Study 30103740 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 16105426 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26350034 — Surrogate Endpoint (SUR): Bone mineral density
Study 26350034 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 10889166 — Monitoring Biomarker (MOI): HBV DNA
Study 29388846 — Safety Biomarker (SAF): Reactive oxygen species
Study 24742019 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16670112 — Surrogate Endpoint (SUR): Blood pressure
Study 14563595 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 31533391 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9600478 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9600478 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9600478 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9600478 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8273794 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 2537217 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2537217 — Surrogate Endpoint (SUR): Blood pressure
Study 23627374 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 23627374 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21301920 — Surrogate Endpoint (SUR): Blood pressure
Study 19156159 — Surrogate Endpoint (SUR): Blood pressure
Study 19156159 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19156159 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11250978 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7601918 — Surrogate Endpoint (SUR): Probing pocket depth
Study 30521105 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28595137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28595137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19228852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9493651 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9493651 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27578132 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27578132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27578132 — Surrogate Endpoint (SUR): Blood pressure
Study 27578132 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8571186 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8571186 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26067186 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23988802 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19297384 — Surrogate Endpoint (SUR): Blood pressure
Study 15136320 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7700067 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7700067 — Surrogate Endpoint (SUR): Blood pressure
Study 7700067 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17090992 — Surrogate Endpoint (SUR): Bone mineral density
Study 9162448 — Surrogate Endpoint (SUR): Blood pressure
Study 6240568 — Predictive Biomarker (PRD): RASGRF1 mRNA
Genes: RASGRF1; CDC25; GNRP; GRF1
Study 22844527 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 22844527 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 12816768 — Surrogate Endpoint (SUR): Blood pressure
Study 14761119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23974642 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 23974642 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 28632666 — Surrogate Endpoint (SUR): Bone mineral density
Study 21570487 — Predictive Biomarker (PRD): Hormone receptor
Study 21570487 — Surrogate Endpoint (SUR): Bone mineral density
Study 1348430 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 1348430 — Safety Biomarker (SAF): DRD2
Study 4064575 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 25530160 — Surrogate Endpoint (SUR): Blood pressure
Study 10483810 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 30037432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25476537 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25476537 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 25476537 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3895254 — Surrogate Endpoint (SUR): Blood pressure
Study 22314936 — Surrogate Endpoint (SUR): Bone mineral density
Study 8644661 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6741802 — Surrogate Endpoint (SUR): Blood pressure
Study 6741802 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22925169 — Surrogate Endpoint (SUR): Blood pressure
Study 22925169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22302316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12494125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 2131864 — Surrogate Endpoint (SUR): Blood pressure
Study 30535396 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 22773240 — Surrogate Endpoint (SUR): Total kidney volume
Study 7988951 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 12888226 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22153774 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 18481319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18481319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12935394 — Surrogate Endpoint (SUR): Bone mineral density
Study 12935394 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12935394 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2882772 — Surrogate Endpoint (SUR): Blood pressure
Study 22796548 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26704762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26704762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26704762 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26704762 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25346460 — Surrogate Endpoint (SUR): Blood pressure
Study 16420547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11282762 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26330422 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 16505650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16505650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16505650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10856536 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20367669 — Predictive Biomarker (PRD): KLK3 mRNA
Genes: KLK3; APS
Study 2663343 — Surrogate Endpoint (SUR): Blood pressure
Study 16468062 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12827024 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23765238 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 12028242 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 1786954 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19463608 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7988298 — Surrogate Endpoint (SUR): Serum potassium
Study 31023428 — Surrogate Endpoint (SUR): Blood pressure
Study 31023428 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28867497 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 23038220 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12414848 — Surrogate Endpoint (SUR): Bone mineral density
Study 9884268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9884268 — Surrogate Endpoint (SUR): Serum creatinine
Study 9884268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31761933 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31761933 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 31761933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30602450 — Surrogate Endpoint (SUR): Blood pressure
Study 16342193 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16342193 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7498231 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 2312773 — Surrogate Endpoint (SUR): Blood pressure
Study 31525129 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30896743 — Surrogate Endpoint (SUR): Bone mineral density
Study 19879131 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 23843569 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21690627 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21690627 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 15570147 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 29072017 — Surrogate Endpoint (SUR): Plasma ammonia
Study 14697480 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 14697480 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30668199 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19730207 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 17410010 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 11849198 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11502643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2879389 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28394087 — Surrogate Endpoint (SUR): Bone mineral density
Study 25319061 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23702231 — Surrogate Endpoint (SUR): Serum creatinine
Study 28390289 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28390289 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26939323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23735418 — Surrogate Endpoint (SUR): Blood pressure
Study 8173195 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8173195 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30575560 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 30575560 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30575560 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27224908 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 23600541 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study 23600541 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20197167 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 12242514 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12242514 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29957709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29957709 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 29957709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 29957709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29957709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21988334 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21988334 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 12483368 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12483368 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24494295 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1769029 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10686660 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10686660 — Surrogate Endpoint (SUR): Blood pressure
Study 9374089 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25391047 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 16055396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 28394081 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 28394081 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26415995 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26415995 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25689258 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 23860406 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23860406 — Surrogate Endpoint (SUR): Blood pressure
Study 17970838 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15982790 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 12852707 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12852707 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30980608 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23498346 — Surrogate Endpoint (SUR): Blood pressure
Study 17019564 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 2930092 — Surrogate Endpoint (SUR): Blood pressure
Study 31958442 — Predictive Biomarker (PRD): HSCB mRNA
Genes: HSCB; DNAJC20; HSC20
Study 23916915 — Surrogate Endpoint (SUR): Blood pressure
Study 7817618 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7817618 — Surrogate Endpoint (SUR): Blood pressure
Study 30836363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26807534 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 12077736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12077736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15357108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15357108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22857983 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1389281 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20705788 — Surrogate Endpoint (SUR): Blood pressure
Study 10914864 — Surrogate Endpoint (SUR): Bone mineral density
Study 21543662 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 21125038 — Surrogate Endpoint (SUR): Serum creatinine
Study 21125038 — Surrogate Endpoint (SUR): Blood pressure
Study 15696181 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1332529 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15886286 — Surrogate Endpoint (SUR): Blood pressure
Study 10636578 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10636578 — Surrogate Endpoint (SUR): Blood pressure
Study 26182172 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23636283 — Surrogate Endpoint (SUR): Blood pressure
Study 19689798 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 19689798 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 19689798 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 19689798 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 19689798 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 19689798 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 19689798 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 19689798 — Predictive Biomarker (PRD): NFAT5 mRNA
Genes: NFAT5; KIAA0827; TONEBP
Study 19689798 — Predictive Biomarker (PRD): CREB5 mRNA
Genes: CREB5; CREBPA
Study 17239165 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 17239165 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11521985 — Surrogate Endpoint (SUR): Blood pressure
Study 30760195 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 21966218 — Surrogate Endpoint (SUR): Blood pressure
Study 21966218 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14561117 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 30245169 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22781352 — Monitoring Biomarker (MOI): HBV DNA
Study 28592620 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28592620 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 21943112 — Predictive Biomarker (PRD): ADIPOR2 mRNA
Genes: ADIPOR2; PAQR2
Study 9093424 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 31468664 — Surrogate Endpoint (SUR): Blood pressure
Study 31468664 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9383115 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9383115 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 9383115 — Surrogate Endpoint (SUR): Blood pressure
Study 22236804 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 21512577 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16776702 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 9324147 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28101658 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21600090 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 17068818 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12511312 — Surrogate Endpoint (SUR): Blood pressure
Study 10371571 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10371571 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 10371571 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31814159 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 31814159 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 17523932 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15050199 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 2455107 — Surrogate Endpoint (SUR): Blood pressure
Study 1579579 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29498344 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 29498344 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 1413981 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31331587 — Surrogate Endpoint (SUR): Blood pressure