TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31502032 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12812861 — Surrogate Endpoint (SUR): Blood pressure
Study 7566020 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2190884 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2190884 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 2190884 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 2190884 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 2190884 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 474381 — Surrogate Endpoint (SUR): Serum potassium
Study 31596723 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28168303 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26177957 — Surrogate Endpoint (SUR): Blood pressure
Study 19637289 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15023378 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8309674 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 29411112 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24986183 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 20960029 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 18786230 — Surrogate Endpoint (SUR): Bone mineral density
Study 2143597 — Surrogate Endpoint (SUR): Serum creatinine
Study 2143597 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31974670 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 25143337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25143337 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18670465 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 19923530 — Surrogate Endpoint (SUR): Blood pressure
Study 2863289 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18023899 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9180289 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24311443 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23881566 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12154110 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31619441 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31619441 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 28371941 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 25863985 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11887898 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study 22999784 — Surrogate Endpoint (SUR): Blood pressure
Study 21640258 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21640258 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 1535051 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 31034350 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 27660163 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27660163 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28241355 — Surrogate Endpoint (SUR): Serum testosterone
Study 25732625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25732625 — Surrogate Endpoint (SUR): Blood pressure
Study 8542099 — Surrogate Endpoint (SUR): Blood pressure
Study 205687 — Predictive Biomarker (PRD): ZGPAT mRNA
Genes: ZGPAT; GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZIP
Study 28601733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28601733 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28601733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15086488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15086488 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11747684 — Surrogate Endpoint (SUR): Bone mineral density
Study 29574365 — Predictive Biomarker (PRD): Hormone receptor
Study 23142295 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 10695692 — Surrogate Endpoint (SUR): Bone mineral density
Study 8267492 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8267492 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31145350 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 20934757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20934757 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17521782 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 11114571 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31162829 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31162829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24356792 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24356792 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19276646 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9869786 — Surrogate Endpoint (SUR): Blood pressure
Study 29160099 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 24874911 — Predictive Biomarker (PRD): ISM1 mRNA
Genes: ISM1; C20orf82; ISM
Study 20648041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25995169 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 25995169 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25995169 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23956164 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28182700 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 25328994 — Predictive Biomarker (PRD): AQP1 mRNA
Genes: AQP1; CHIP28
Study 18716157 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 18716157 — Safety Biomarker (SAF): Reactive oxygen species
Study 18716157 — Safety Biomarker (SAF): Cytochrome c
Study 8683243 — Surrogate Endpoint (SUR): Serum creatinine
Study 8683243 — Surrogate Endpoint (SUR): Blood pressure
Study 31396686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29105958 — Surrogate Endpoint (SUR): Blood pressure
Study 7677125 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7677125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28624340 — Surrogate Endpoint (SUR): Bone mineral density
Study 24620015 — Surrogate Endpoint (SUR): Blood pressure
Study 16510331 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 16510331 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 78718 — Surrogate Endpoint (SUR): Blood pressure
Study 28606735 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 19729401 — Surrogate Endpoint (SUR): Blood pressure
Study 17250690 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 29317666 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15470798 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 2561015 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 26927283 — Predictive Biomarker (PRD): INSIG1 mRNA
Genes: INSIG1
Study 26927283 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26927283 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19491220 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 19491220 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 19491220 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 17326082 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 17326082 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 15075538 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15075538 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 15075538 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9571515 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 7919965 — Safety Biomarker (SAF): RFC1
Genes: A1; PO-GA; RFC140; MHCBFB
Study 7919965 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31319002 — Surrogate Endpoint (SUR): Blood pressure
Study 30171747 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24132374 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24132374 — Surrogate Endpoint (SUR): Blood pressure
Study 30742834 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 6991196 — Surrogate Endpoint (SUR): Blood pressure
Study 28179255 — Predictive Biomarker (PRD): FAM168B mRNA
Genes: FAM168B; KIAA0280L; MANI
Study 10717782 — Predictive Biomarker (PRD): MENT mRNA
Genes: MENT; C1orf56; UNQ547/PRO1104
Study 6152885 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6152885 — Surrogate Endpoint (SUR): Blood pressure
Study 28138734 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 23448107 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 21270204 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8361862 — Surrogate Endpoint (SUR): Blood pressure
Study 29659896 — Surrogate Endpoint (SUR): Blood pressure
Study 20718183 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20718183 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 20718183 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8860710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8860710 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28768848 — Surrogate Endpoint (SUR): Blood pressure
Study 19410683 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2232453 — Surrogate Endpoint (SUR): Blood pressure
Study 20130569 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 20130569 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9609749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 201592 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27056686 — Safety Biomarker (SAF): Hyaluronic acid
Study 25543089 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30879375 — Predictive Biomarker (PRD): EVC mRNA
Genes: EVC
Study 30879375 — Surrogate Endpoint (SUR): Blood pressure
Study 27881381 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 15575909 — Surrogate Endpoint (SUR): Bone mineral density
Study 15575909 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15575909 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 11685731 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 3283061 — Surrogate Endpoint (SUR): Blood pressure
Study 22719231 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7243605 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27545448 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20031131 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20031131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18211609 — Safety Biomarker (SAF): Reactive oxygen species
Study 10479134 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8759414 — Surrogate Endpoint (SUR): Blood pressure
Study 8759414 — Surrogate Endpoint (SUR): Serum potassium
Study 7694894 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 29475793 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 29475793 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 27306792 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study 24926548 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 24926548 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 22814125 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19397632 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15050905 — Surrogate Endpoint (SUR): Bone mineral density
Study 7502628 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11590482 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11590482 — Safety Biomarker (SAF): Interleukin 1
Study 31455229 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18637168 — Surrogate Endpoint (SUR): Blood pressure
Study 9376575 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9376575 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24848838 — Predictive Biomarker (PRD): Hormone receptor
Study 18058480 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18058480 — Surrogate Endpoint (SUR): Blood pressure
Study 12135223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12135223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21191361 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 19054806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12359410 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 16913261 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 9051544 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16424842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16424842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16424842 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 16424842 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16424842 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16424842 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 1847704 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1847704 — Surrogate Endpoint (SUR): Serum potassium
Study 12947272 — Surrogate Endpoint (SUR): Blood pressure
Study 19294953 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 29621660 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 26453914 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22228118 — Surrogate Endpoint (SUR): Bone mineral density
Study 15811481 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 21714585 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 21714585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21714585 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2339203 — Surrogate Endpoint (SUR): Blood pressure
Study 25791863 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21801476 — Surrogate Endpoint (SUR): Blood pressure
Study 12196498 — Surrogate Endpoint (SUR): Bone mineral density
Study 7778543 — Surrogate Endpoint (SUR): Blood pressure
Study 7778543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20034629 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20034629 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29266965 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26440923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26591679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23180950 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 15793094 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11934246 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 11934246 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17179509 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14600553 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 14600553 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 9366278 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9366278 — Surrogate Endpoint (SUR): Blood pressure
Study 9366278 — Surrogate Endpoint (SUR): Serum potassium
Study 12225436 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 10223773 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 680588 — Surrogate Endpoint (SUR): Serum sodium
Study 680588 — Surrogate Endpoint (SUR): Serum uric acid
Study 25596939 — Surrogate Endpoint (SUR): Blood pressure
Study 23414585 — Predictive Biomarker (PRD): Hormone receptor
Study 23505176 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23505176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17009533 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25626738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25626738 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25626738 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 2563321 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23950589 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 14724157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14724157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18434902 — Surrogate Endpoint (SUR): Blood pressure
Study 16215921 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7828379 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22871888 — Surrogate Endpoint (SUR): Blood pressure
Study 18242616 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18242616 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 18242616 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8861689 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8861689 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 11512369 — Surrogate Endpoint (SUR): Blood pressure
Study 3508329 — Surrogate Endpoint (SUR): Serum creatinine
Study 24630840 — Surrogate Endpoint (SUR): Serum testosterone
Study 30074288 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 27513640 — Surrogate Endpoint (SUR): Blood pressure
Study 19839000 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19839000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19839000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19839000 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15998749 — Surrogate Endpoint (SUR): Blood pressure
Study 10388246 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8671813 — Surrogate Endpoint (SUR): Serum creatinine
Study 31955859 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 31618331 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31125186 — Surrogate Endpoint (SUR): Blood pressure
Study 29578858 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 29578858 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10221717 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10221717 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8519717 — Surrogate Endpoint (SUR): Blood pressure
Study 29295829 — Surrogate Endpoint (SUR): Serum creatinine
Study 20739842 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18467618 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 31335802 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27372432 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27372432 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 23356505 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12679359 — Surrogate Endpoint (SUR): Blood pressure
Study 23496861 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 15012688 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15012688 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 15012688 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15012688 — Safety Biomarker (SAF): Hyaluronic acid
Study 24582071 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 15168040 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1