TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30452706 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29776960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 29776960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29776960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29776960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22864647 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 25163489 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 7581113 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28284835 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 17242081 — Surrogate Endpoint (SUR): Blood pressure
Study 27272818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27272818 — Safety Biomarker (SAF): Interleukin 1
Study 22290239 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22290239 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25528574 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 19884557 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 14735021 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 14735021 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 25318000 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25318000 — Surrogate Endpoint (SUR): Blood pressure
Study 22318246 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 22318246 — Surrogate Endpoint (SUR): Blood pressure
Study 22318246 — Surrogate Endpoint (SUR): Serum creatinine
Study 20488408 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 18588360 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 7342654 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 7342654 — Predictive Biomarker (PRD): PAMR1 mRNA
Genes: PAMR1; RAMP; FP938; UNQ699/PRO1344
Study 31474719 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19455620 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 15646031 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 15646031 — Safety Biomarker (SAF): Reactive oxygen species
Study 15646031 — Surrogate Endpoint (SUR): Blood pressure
Study 11198728 — Surrogate Endpoint (SUR): Blood pressure
Study 29117913 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28081962 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28081962 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 21161543 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study 11092410 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 11092410 — Surrogate Endpoint (SUR): Bone mineral density
Study 11092410 — Surrogate Endpoint (SUR): Serum calcium
Study 3519005 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3519005 — Surrogate Endpoint (SUR): Blood pressure
Study 22237259 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22237259 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 22237259 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 16181368 — Monitoring Biomarker (MOI): HBV DNA
Study 25335326 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25335326 — Surrogate Endpoint (SUR): Blood pressure
Study 25335326 — Surrogate Endpoint (SUR): Serum creatinine
Study 22088966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22088966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1991925 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 10782805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8988539 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 6379120 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 23821397 — Safety Biomarker (SAF): Reactive oxygen species
Study 18653184 — Surrogate Endpoint (SUR): Bone mineral density
Study 15096442 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11497535 — Surrogate Endpoint (SUR): Bone mineral density
Study 9504447 — Surrogate Endpoint (SUR): Blood pressure
Study 26578852 — Surrogate Endpoint (SUR): Serum creatinine
Study 19061704 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8342759 — Surrogate Endpoint (SUR): Serum creatinine
Study 30392388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30392388 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30392388 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30392388 — Surrogate Endpoint (SUR): Blood pressure
Study 26621631 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26621631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26621631 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 22075942 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12900342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12900342 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 12900342 — Safety Biomarker (SAF): IL-6 and IL-10
Study 27633250 — Safety Biomarker (SAF): Reactive oxygen species
Study 21673083 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21673083 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16528977 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9432405 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1576046 — Surrogate Endpoint (SUR): Blood pressure
Study 12771007 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7287240 — Surrogate Endpoint (SUR): Blood pressure
Study 26484902 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 22963378 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 15305311 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 8062521 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29325660 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 22512264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20810376 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 30125457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21733177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21733177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21733177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16704986 — Safety Biomarker (SAF): Reactive oxygen species
Study 7555530 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7555530 — Surrogate Endpoint (SUR): Blood pressure
Study 2340615 — Surrogate Endpoint (SUR): Blood pressure
Study 15058157 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29866583 — Surrogate Endpoint (SUR): Blood pressure
Study 20129356 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 18392690 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18392690 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31765604 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 19996335 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18446021 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12881451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6398983 — Surrogate Endpoint (SUR): Blood pressure
Study 30550982 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30550982 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30550982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22261578 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7152443 — Surrogate Endpoint (SUR): Serum uric acid
Study 15705733 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 9854508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 329291 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 31472930 — Surrogate Endpoint (SUR): Blood pressure
Study 23816493 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3666661 — Surrogate Endpoint (SUR): Blood pressure
Study 25515553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25515553 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22901969 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 7669483 — Surrogate Endpoint (SUR): Blood pressure
Study 31862174 — Surrogate Endpoint (SUR): Blood pressure
Study 7996800 — Surrogate Endpoint (SUR): Blood pressure
Study 24508036 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22730850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11249891 — Surrogate Endpoint (SUR): Blood pressure
Study 25724847 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10671676 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 10671676 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29726280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27546373 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22689417 — Surrogate Endpoint (SUR): Blood pressure
Study 11177300 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9076203 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9076203 — Surrogate Endpoint (SUR): Blood pressure
Study 8360066 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24384495 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30982983 — Predictive Biomarker (PRD): PIAS1 mRNA
Genes: PIAS1; DDXBP1
Study 30982983 — Safety Biomarker (SAF): Reactive oxygen species
Study 25281223 — Surrogate Endpoint (SUR): Blood pressure
Study 23812296 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study 23812296 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 23812296 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1416164 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22212113 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 6779371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20826553 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 8239101 — Predictive Biomarker (PRD): GSC mRNA
Genes: GSC
Study 18579283 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 12006956 — Surrogate Endpoint (SUR): Plasma ammonia
Study 7473451 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 7473451 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 7473451 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1685182 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6315329 — Surrogate Endpoint (SUR): Blood pressure
Study 1611649 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30561059 — Surrogate Endpoint (SUR): Blood pressure
Study 26582633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26582633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26582633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9869598 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 9869598 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9869598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9869598 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9869598 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20298820 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15764039 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 7805972 — Surrogate Endpoint (SUR): Blood pressure
Study 23511556 — Predictive Biomarker (PRD): NCOA3 mRNA
Genes: NCOA3; AIB1; BHLHE42; RAC3; TRAM1
Study 23511556 — Predictive Biomarker (PRD): E2F1 mRNA
Genes: E2F1; RBBP3
Study 19081393 — Surrogate Endpoint (SUR): Blood pressure
Study 8440931 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 3619219 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28350401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9021437 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7940144 — Surrogate Endpoint (SUR): Blood pressure
Study 31246714 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16927920 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 12830439 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 14639559 — Surrogate Endpoint (SUR): Blood pressure
Study 2442506 — Surrogate Endpoint (SUR): Blood pressure
Study 28315068 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28315068 — Predictive Biomarker (PRD): Hormone receptor
Study 26508749 — Surrogate Endpoint (SUR): Blood pressure
Study 26508749 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14606508 — Surrogate Endpoint (SUR): Bone mineral density
Study 16820373 — Surrogate Endpoint (SUR): Serum creatinine
Study 16820373 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16820373 — Surrogate Endpoint (SUR): Blood pressure
Study 15585141 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24630293 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 15764959 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15764959 — Surrogate Endpoint (SUR): Bone mineral density
Study 29666071 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8190534 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3296979 — Surrogate Endpoint (SUR): Blood pressure
Study 3296979 — Surrogate Endpoint (SUR): Serum potassium
Study 20097461 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20097461 — Surrogate Endpoint (SUR): Blood pressure
Study 8701396 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 8701396 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8701396 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 1521779 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study 1521779 — Surrogate Endpoint (SUR): Bone mineral density
Study 1521779 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 31964428 — Surrogate Endpoint (SUR): Blood pressure
Study 23040657 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22185726 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22185726 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 22185726 — Surrogate Endpoint (SUR): Blood pressure
Study 24219814 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 20880093 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 18926162 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 14756461 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 31092019 — Surrogate Endpoint (SUR): Blood pressure
Study 31092019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23169362 — Surrogate Endpoint (SUR): Serum creatinine
Study 23169362 — Surrogate Endpoint (SUR): Blood pressure
Study 16014845 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10193779 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 26109814 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26109814 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26109814 — Surrogate Endpoint (SUR): Serum creatinine
Study 8021573 — Surrogate Endpoint (SUR): Blood pressure
Study 2561594 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2561594 — Surrogate Endpoint (SUR): Blood pressure
Study 16152600 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8744166 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 31002147 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 18538118 — Surrogate Endpoint (SUR): Blood pressure
Study 10229733 — Surrogate Endpoint (SUR): Blood pressure
Study 17571284 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 355958 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19458605 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16317423 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 16317423 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 16317423 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3302148 — Surrogate Endpoint (SUR): Blood pressure
Study 27209269 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25189358 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15630733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12021690 — Surrogate Endpoint (SUR): Blood pressure
Study 8547380 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 30989966 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 28419834 — Surrogate Endpoint (SUR): Blood pressure
Study 26814106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26814106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23014927 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16796836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18192132 — Surrogate Endpoint (SUR): Blood pressure
Study 16169353 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 10229296 — Predictive Biomarker (PRD): PLK2 mRNA
Genes: PLK2; SNK
Study 26681630 — Surrogate Endpoint (SUR): Blood pressure
Study 21481265 — Surrogate Endpoint (SUR): Blood pressure
Study 21975580 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 21975580 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 21975580 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 16019368 — Surrogate Endpoint (SUR): Serum testosterone
Study 8027217 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8027217 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26473986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26473986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22211402 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 22211402 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 7670342 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 25526906 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25526906 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23648344 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1551748 — Surrogate Endpoint (SUR): Blood pressure
Study 31618127 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24772445 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24772445 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20159245 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 20159245 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20159245 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20159245 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11821721 — Surrogate Endpoint (SUR): Blood pressure
Study 31779925 — Surrogate Endpoint (SUR): Blood pressure
Study 21130977 — Surrogate Endpoint (SUR): Blood pressure
Study 17984166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17984166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7931739 — Surrogate Endpoint (SUR): Blood pressure
Study 19470154 — Safety Biomarker (SAF): Hyaluronic acid
Study 17894335 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 15041714 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 11585606 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T