TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03159663 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT01950585 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01950585 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02821585 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02021591 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02021591 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01394887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01394887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02277392 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT02277392 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT03134261 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02900313 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01480011 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study NCT02715726 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02715726 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02715726 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01448005 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00797238 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT00797238 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study NCT00797238 — Predictive Biomarker (PRD): XRCC3 mRNA
Genes: XRCC3
Study NCT00797238 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00797238 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study NCT02410265 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03096938 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00895960 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT00895960 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02443376 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02364609 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02284074 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT04003207 — Predictive Biomarker (PRD): SHANK3 mRNA
Genes: SHANK3; KIAA1650; PROSAP2; PSAP2
Study NCT02038088 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05306002 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05306002 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04400578 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03055455 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03776773 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04314258 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04314258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04314258 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04314258 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00514345 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT00075920 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00490139 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00490139 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT04608162 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04018131 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT04018131 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT04018131 — Safety Biomarker (SAF): Interleukin 12
Study NCT04018131 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03689244 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01837264 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01367808 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03979482 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study NCT03979482 — Predictive Biomarker (PRD): PPARGC1B mRNA
Genes: PPARGC1B; PERC; PGC1; PGC1B; PPARGC1
Study NCT02285530 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study NCT01014455 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT00259688 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01340508 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02990195 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study NCT00021905 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00025623 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study NCT04483440 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study NCT03592641 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01362452 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01397604 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT02465528 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00184899 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04600765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02447211 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT02983422 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03252535 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03489668 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT03934580 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT03934580 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT03934580 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01047059 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01047059 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01047059 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03869125 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00079274 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04367545 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01286467 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study NCT00514215 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00315133 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02752217 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02791516 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01589523 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study NCT04020198 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT02048215 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study NCT02048215 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00631787 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01322373 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT00026988 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01960348 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT00629317 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT01806649 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01806649 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01806649 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study NCT00748956 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT01539382 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04542070 — Predictive Biomarker (PRD): BIK mRNA
Genes: BIK; NBK
Study NCT02363231 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT02115178 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT02115178 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04156178 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04151706 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01608451 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT02464514 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT03697200 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02985242 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00323128 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00715793 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study NCT03470103 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00094653 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT00094653 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00472667 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02393053 — Predictive Biomarker (PRD): TKT mRNA
Genes: TKT
Study NCT02591628 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02064738 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04406688 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT02048410 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT00447473 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02406443 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04504942 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02736513 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02188381 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04284696 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study NCT00679341 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00779454 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00879671 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02309281 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00444002 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study NCT00444002 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04188652 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT00431249 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00431249 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04473365 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04473365 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01101698 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT01120561 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04574661 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03168347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03168347 — Safety Biomarker (SAF): Interleukin 12
Study NCT02921685 — Predictive Biomarker (PRD): KLRD1 mRNA
Genes: KLRD1; CD94
Study NCT02921685 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study NCT02375971 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02375971 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03214250 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04363853 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00979329 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00979329 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03992326 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT04311034 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02719145 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-20a
Genes: MIR20A
Study NCT02719145 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT02719145 — Safety Biomarker (SAF): miR-22
Genes: MIR22
Study NCT02719145 — Predictive Biomarker (PRD): miR-145
Genes: MIR145
Study NCT02719145 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT00952874 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04465565 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04225819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02844283 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT00001307 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02172950 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT03730545 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03730545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03730545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01193062 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study NCT02502786 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03685331 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03685331 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03685331 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03685331 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03685331 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03685331 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02988999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02988999 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02988999 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02988999 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02988999 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01574846 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00174538 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT03913143 — Predictive Biomarker (PRD): CEP290 mRNA
Genes: CEP290; BBS14; KIAA0373; NPHP6
Study NCT00729352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study NCT04630717 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00993499 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03908827 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02113462 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02113462 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04603872 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04603872 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04290923 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT04031872 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04237623 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02819973 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01689467 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02735798 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02806817 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02806817 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study NCT02806817 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study NCT00099281 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03927222 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02836054 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03828877 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT00815347 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT01554293 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02520700 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00001941 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00001941 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT00001941 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00001941 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00591604 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03867019 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00357656 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT05372016 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04608266 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT03906669 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03906669 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03906669 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02044614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02044614 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02157129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02157129 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT02157129 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02157129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02157129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03756922 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04743544 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00507104 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT00507104 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01026519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02134613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02906696 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02906696 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04515628 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT00239681 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00239681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04321629 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02310659 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02616224 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01662635 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study NCT01662635 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02222077 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00853840 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04287686 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04287686 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04087070 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03672071 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03344198 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02008357 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study NCT00821249 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03452280 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02285361 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02285361 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02690285 — Predictive Biomarker (PRD): GSTZ1 mRNA
Genes: GSTZ1; MAAI
Study NCT03623737 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00001180 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT04596085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01174485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01240681 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00930436 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00381875 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01150201 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00237952 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02337166 — Safety Biomarker (SAF): Hyaluronic acid