TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05339789 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04456387 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT01797367 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02646020 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02646020 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03666039 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03666039 — Safety Biomarker (SAF): BDNF
Study NCT03421912 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02160730 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT05288829 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT04507191 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04467281 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT00822770 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04647838 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02115620 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02489383 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02153580 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02153580 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT02153580 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01497301 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02932618 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00915226 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00517361 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01620190 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01620190 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00002837 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04207060 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT00003874 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04488406 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02082704 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT06202976 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT02580747 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT01575873 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00335101 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02978196 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02445651 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT02705339 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02649205 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02649205 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT02649205 — Surrogate Endpoint (SUR): Serum phosphate
Study NCT04473248 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04560647 — Predictive Biomarker (PRD): TP63 mRNA
Genes: TP63; KET; P63; P73H; P73L; TP73L
Study NCT00129753 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT02207686 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT03793881 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03793881 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03793881 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03793881 — Surrogate Endpoint (SUR): Serum sodium
Study NCT03793881 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02400281 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01636674 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT01636674 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02976740 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02108002 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT01465763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02779790 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04396158 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04456192 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04456192 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04456192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04456192 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04456192 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04456192 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04456192 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00100516 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001668 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT02161380 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT00220194 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT03669029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02074839 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT03384641 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT01126385 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01903330 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03070262 — Predictive Biomarker (PRD): KDM4C mRNA
Genes: KDM4C; GASC1; JHDM3C; JMJD2C; KIAA0780
Study NCT01557374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04676035 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04676035 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT04676035 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01208779 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01195480 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02275156 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04356534 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00921947 — Surrogate Endpoint (SUR): Serum antibody concentration
Study NCT04051086 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study NCT02604823 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03872856 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01017718 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02205242 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study NCT04336215 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05321524 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT02706158 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04778995 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05333302 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04559100 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02002377 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03066882 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03066882 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02329379 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00321295 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00955890 — Safety Biomarker (SAF): Cardiac troponin T
Genes: TNNT2
Study NCT00955890 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT02871167 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT03157752 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00235794 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT01088620 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01088620 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06248437 — Predictive Biomarker (PRD): HIC1 mRNA
Genes: HIC1; ZBTB29
Study NCT00023998 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01144377 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00242996 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04977791 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT04977791 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT04977791 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT04977791 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT00130611 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00064792 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT00753233 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02585895 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04520750 — Predictive Biomarker (PRD): KRT6A mRNA
Genes: KRT6A; K6A; KRT6D
Study NCT04520750 — Predictive Biomarker (PRD): KRT6B mRNA
Genes: KRT6B; K6B; KRTL1
Study NCT04520750 — Predictive Biomarker (PRD): KRT16 mRNA
Genes: KRT16; KRT16A
Study NCT04520750 — Predictive Biomarker (PRD): KRT6C mRNA
Genes: KRT6C; KRT6E
Study NCT04520750 — Predictive Biomarker (PRD): KRT17 mRNA
Genes: KRT17
Study NCT01060228 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00607724 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study NCT04851769 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02775006 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02775006 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02775006 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01918592 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study NCT00279253 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01141192 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00563784 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00563784 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03162419 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT03384303 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT00309647 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00551850 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00551850 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00129935 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00129935 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00129935 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00662168 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study NCT00286234 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03285607 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03285607 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03285607 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03285607 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01703728 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT01853501 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT04962529 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04342143 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01168817 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01387568 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01764984 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02622555 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04659525 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04659525 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01686139 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00698568 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT03033303 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01007110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02313142 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03879798 — Predictive Biomarker (PRD): EZH2
Genes: EZH1; ENX-1; KMT6; KMT6A
Study NCT04139317 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04139317 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04139317 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04139317 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT03916003 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT03850392 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02493361 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01218347 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT01502046 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01502046 — Predictive Biomarker (PRD): CBR1 mRNA
Genes: CBR1; CBR; CRN; SDR21C1
Study NCT01502046 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01502046 — Safety Biomarker (SAF): BDNF
Study NCT03579810 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01079494 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01487187 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00687843 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT02287103 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00246636 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02946671 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study NCT02811718 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT02811718 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT02214511 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT02214511 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02214511 — Predictive Biomarker (PRD): PECAM1 mRNA
Genes: PECAM1
Study NCT01953926 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01953926 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04230473 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01592045 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01592045 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03618862 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT03618862 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02579590 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT03441100 — Predictive Biomarker (PRD): MAGEA1 mRNA
Genes: MAGEA1; MAGE1; MAGE1A
Study NCT01901809 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01725594 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT03051308 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT03320135 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT03324386 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03993808 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03178552 — Predictive Biomarker (PRD): TP53INP2 mRNA
Genes: TP53INP2; C20orf110; DOR; PINH
Study NCT03178552 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study NCT03178552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT03178552 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01273324 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02623621 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04323436 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04532905 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00169156 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT01316367 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01316367 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00465842 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT03664440 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03664440 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study NCT03664440 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04278027 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04278027 — Safety Biomarker (SAF): BDNF
Study NCT02993523 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00958399 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT01755871 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04917679 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT03893500 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04511689 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02954978 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT03952078 — Predictive Biomarker (PRD): ITK mRNA
Genes: ITK; EMT; LYK
Study NCT01296555 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01296555 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04787978 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00337766 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT02630212 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study NCT04377646 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02763384 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT04358445 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT03662594 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study NCT01337440 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02979535 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04482751 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02127203 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02008227 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04452214 — Predictive Biomarker (PRD): IL1RAP mRNA
Genes: IL1RAP; C3orf13; IL1R3
Study NCT03002298 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01078363 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00282659 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00282659 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04224012 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04224012 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02222376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02222376 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01468792 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02956837 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00656864 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00409487 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04001647 — Predictive Biomarker (PRD): ATF6 mRNA
Genes: ATF6
Study NCT04001647 — Predictive Biomarker (PRD): EIF2AK3 mRNA
Genes: EIF2AK3; PEK; PERK
Study NCT04001647 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT04001647 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study NCT02391142 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00580060 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02175823 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002687 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02389764 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03878420 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00307073 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study NCT05727982 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study NCT03394586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01578577 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03873649 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01175096 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01175096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00636740 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study NCT01064700 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04348032 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00006058 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT03348891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2