TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9012545 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1376812 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1376812 — Surrogate Endpoint (SUR): Blood pressure
Study 27421057 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24645793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24645793 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23235391 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23235391 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17828687 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 10342360 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 10342360 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10342360 — Surrogate Endpoint (SUR): Blood pressure
Study 8954380 — Surrogate Endpoint (SUR): Blood pressure
Study 11497195 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11497195 — Surrogate Endpoint (SUR): Blood pressure
Study 11497195 — Surrogate Endpoint (SUR): Serum creatinine
Study 9032212 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 9032212 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 2938394 — Surrogate Endpoint (SUR): Blood pressure
Study 25335325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25335325 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1673050 — Surrogate Endpoint (SUR): Blood pressure
Study 28270226 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 28270226 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 9850487 — Surrogate Endpoint (SUR): Blood pressure
Study 23936607 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 23936607 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21524765 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 21524765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6373442 — Surrogate Endpoint (SUR): Blood pressure
Study 6373442 — Surrogate Endpoint (SUR): Serum uric acid
Study 26773906 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22473809 — Surrogate Endpoint (SUR): Serum creatinine
Study 15492301 — Surrogate Endpoint (SUR): Blood pressure
Study 8139479 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 8139479 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17318860 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17318860 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17318860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15100697 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28150423 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 14695863 — Surrogate Endpoint (SUR): Bone mineral density
Study 23436437 — Surrogate Endpoint (SUR): Blood pressure
Study 15223884 — Surrogate Endpoint (SUR): Blood pressure
Study 29853843 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 22024477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19571633 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 15143716 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8955653 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 30012193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21604039 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 18019592 — Surrogate Endpoint (SUR): Blood pressure
Study 12168782 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 21219381 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 21219381 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 14985485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31077582 — Predictive Biomarker (PRD): LANCL2 mRNA
Genes: LANCL2; GPR69B; TASP
Study 31077582 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 31077582 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31077582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30915987 — Predictive Biomarker (PRD): PDXK mRNA
Genes: PDXK; C21orf124; C21orf97; PKH; PNK; PRED79
Study 23470803 — Surrogate Endpoint (SUR): Blood pressure
Study 20957659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17060046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10638985 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9344321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9344321 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9344321 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28793884 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28793884 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 28793884 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 11257276 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 24333186 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 24198581 — Surrogate Endpoint (SUR): Blood pressure
Study 20849801 — Surrogate Endpoint (SUR): Serum calcium
Study 12958329 — Surrogate Endpoint (SUR): Blood pressure
Study 12958329 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10980588 — Surrogate Endpoint (SUR): Blood pressure
Study 8628544 — Surrogate Endpoint (SUR): Blood pressure
Study 31177595 — Predictive Biomarker (PRD): TLL1 mRNA
Genes: TLL1; TLL
Study 29301520 — Surrogate Endpoint (SUR): Blood pressure
Study 23789873 — Safety Biomarker (SAF): Hyaluronic acid
Study 2057467 — Surrogate Endpoint (SUR): Blood pressure
Study 2057467 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22120044 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 19878615 — Predictive Biomarker (PRD): XPAC mRNA
Genes: XPA; XPAC
Study 19878615 — Predictive Biomarker (PRD): XPC mRNA
Genes: XPC; XPCC
Study 19878615 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 19878615 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 19878615 — Predictive Biomarker (PRD): ERCC5 mRNA
Genes: ERCC5; ERCM2; XPG; XPGC
Study 19878615 — Predictive Biomarker (PRD): ERCC6 mRNA
Genes: ERCC6
Study 19878615 — Predictive Biomarker (PRD): RAD23B mRNA
Genes: RAD23B
Study 15939621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15939621 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15939621 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2759694 — Surrogate Endpoint (SUR): Serum creatinine
Study 22303705 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30055940 — Predictive Biomarker (PRD): F2RL3 mRNA
Genes: F2RL3; PAR4
Study 27930518 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 22343174 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10449889 — Surrogate Endpoint (SUR): Blood pressure
Study 377081 — Surrogate Endpoint (SUR): Serum uric acid
Study 25286684 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29489494 — Surrogate Endpoint (SUR): Blood pressure
Study 26864951 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22891219 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 10752814 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 4031109 — Surrogate Endpoint (SUR): Blood pressure
Study 31808598 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 31808598 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 26580240 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24007570 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 19082699 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9301350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9301350 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9301350 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9301350 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25499944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25499944 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20134177 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15722593 — Surrogate Endpoint (SUR): Bone mineral density
Study 8952583 — Surrogate Endpoint (SUR): Blood pressure
Study 29785399 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12140146 — Pharmacodynamic Biomarker (PDY): CD99 antigen
Genes: CD99; MIC2; MIC2X; MIC2Y
Study 20537501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18544001 — Surrogate Endpoint (SUR): Serum creatinine
Study 15752161 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9758088 — Surrogate Endpoint (SUR): Blood pressure
Study 9758088 — Surrogate Endpoint (SUR): Serum creatinine
Study 30977081 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 31530577 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 24442886 — Surrogate Endpoint (SUR): Bone mineral density
Study 22435747 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2169703 — Surrogate Endpoint (SUR): Blood pressure
Study 26318757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17142825 — Surrogate Endpoint (SUR): Blood pressure
Study 17091139 — Predictive Biomarker (PRD): MUC22 mRNA
Genes: MUC22; G4; PBMUCL1
Study 14751362 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 14751362 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29762642 — Safety Biomarker (SAF): Hyaluronic acid
Study 25264753 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16757158 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16757158 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 16757158 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 16757158 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22718030 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22718030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22718030 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22718030 — Surrogate Endpoint (SUR): Blood pressure
Study 6504709 — Surrogate Endpoint (SUR): Blood pressure
Study 6504709 — Surrogate Endpoint (SUR): Serum uric acid
Study 30043524 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30043524 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26807718 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26807718 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24972936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10395630 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10395630 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 1909085 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27623561 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 18210156 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 18210156 — Predictive Biomarker (PRD): IGFBP5 mRNA
Genes: IGFBP5; IBP5
Study 12727966 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12727966 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12727966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 1317910 — Surrogate Endpoint (SUR): Blood pressure
Study 27293194 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 26371397 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22980373 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22980373 — Surrogate Endpoint (SUR): Blood pressure
Study 27395349 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10333897 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8624083 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 8624083 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 8624083 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 1760811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1760811 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1760811 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24820046 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18977274 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8018020 — Surrogate Endpoint (SUR): Blood pressure
Study 8313931 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30975178 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 19309251 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18690935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3145972 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29956883 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29956883 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27135249 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 16613273 — Predictive Biomarker (PRD): ARHGEF12 mRNA
Genes: ARHGEF12; KIAA0382; LARG
Study 9547934 — Surrogate Endpoint (SUR): Blood pressure
Study 21179101 — Surrogate Endpoint (SUR): Blood pressure
Study 21179101 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7924366 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23296826 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19139845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17005074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17005074 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9988392 — Surrogate Endpoint (SUR): Serum testosterone
Study 2121564 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2121564 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 19369910 — Predictive Biomarker (PRD): DTNBP1 mRNA
Genes: DTNBP1; BLOC1S8; My031
Study 16733865 — Monitoring Biomarker (MOI): HBV DNA
Study 11227239 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9355712 — Surrogate Endpoint (SUR): Serum creatinine
Study 8467614 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 8467614 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3896279 — Surrogate Endpoint (SUR): Blood pressure
Study 28082531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28082531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21317203 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21317203 — Predictive Biomarker (PRD): Hormone receptor
Study 19061882 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12638399 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 3280483 — Surrogate Endpoint (SUR): Blood pressure
Study 10385494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30725315 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 21914313 — Surrogate Endpoint (SUR): Blood pressure
Study 14514946 — Safety Biomarker (SAF): Human leucocyte antigen
Study 1829901 — Surrogate Endpoint (SUR): Blood pressure
Study 1829901 — Surrogate Endpoint (SUR): Serum potassium
Study 17663100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17663100 — Surrogate Endpoint (SUR): Blood pressure
Study 7609517 — Surrogate Endpoint (SUR): Blood pressure
Study 3539691 — Surrogate Endpoint (SUR): Blood pressure
Study 22850935 — Surrogate Endpoint (SUR): Bone mineral density
Study 19432693 — Surrogate Endpoint (SUR): Blood pressure
Study 17088127 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 17088127 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17088127 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26889617 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 21294143 — Monitoring Biomarker (MOI): HBV DNA
Study 19057883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16371605 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 15327421 — Surrogate Endpoint (SUR): Blood pressure
Study 26090394 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22549432 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 22549432 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19464865 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 7200736 — Surrogate Endpoint (SUR): Blood pressure
Study 20963411 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 20963411 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 18426091 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9743309 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 23219236 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 23219236 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23219236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12886826 — Surrogate Endpoint (SUR): Bone mineral density
Study 8439201 — Predictive Biomarker (PRD): HLA-A mRNA
Genes: HLA-A; HLAA
Study 31357402 — Surrogate Endpoint (SUR): Blood pressure
Study 22163454 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22163454 — Surrogate Endpoint (SUR): Blood pressure
Study 10208142 — Surrogate Endpoint (SUR): Serum creatinine
Study 8903607 — Surrogate Endpoint (SUR): Serum potassium
Study 26418629 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 26402815 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17132351 — Surrogate Endpoint (SUR): Blood pressure
Study 18997913 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23318995 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15309879 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15309879 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8121962 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 20462055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15557131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29695902 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22344744 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22344744 — Safety Biomarker (SAF): BDNF
Study 16765100 — Surrogate Endpoint (SUR): Blood pressure
Study 6991446 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 15475437 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10442372 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1914554 — Surrogate Endpoint (SUR): Blood pressure
Study 17410097 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 17410097 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8018617 — Surrogate Endpoint (SUR): Blood pressure
Study 8018617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16740758 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 3818510 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16235461 — Surrogate Endpoint (SUR): Blood pressure
Study 22770372 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22770372 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor