TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29329233 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21354549 — Surrogate Endpoint (SUR): Blood pressure
Study 11108899 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11108899 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 14996776 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14996776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11475557 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 7594429 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7594429 — Surrogate Endpoint (SUR): Blood pressure
Study 28347540 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28347540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21156702 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 19717506 — Surrogate Endpoint (SUR): Blood pressure
Study 19717506 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17451140 — Surrogate Endpoint (SUR): Blood pressure
Study 25389641 — Surrogate Endpoint (SUR): Blood pressure
Study 21169060 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17062685 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 12712781 — Surrogate Endpoint (SUR): Blood pressure
Study 11107075 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2989349 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2989349 — Surrogate Endpoint (SUR): Blood pressure
Study 25453518 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 20974575 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20974575 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 10594426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31836434 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31836434 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31563038 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16492207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16492207 — Surrogate Endpoint (SUR): Blood pressure
Study 22555328 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 17805075 — Surrogate Endpoint (SUR): Bone mineral density
Study 30418098 — Surrogate Endpoint (SUR): Blood pressure
Study 23416718 — Surrogate Endpoint (SUR): Blood pressure
Study 16923247 — Safety Biomarker (SAF): Reactive oxygen species
Study 16923247 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10424316 — Surrogate Endpoint (SUR): Blood pressure
Study 30886898 — Monitoring Biomarker (MOI): Procalcitonin
Study 28146658 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24052416 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 17021352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9527746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7888516 — Surrogate Endpoint (SUR): Blood pressure
Study 31567592 — Surrogate Endpoint (SUR): Blood pressure
Study 31601989 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21084154 — Surrogate Endpoint (SUR): Blood pressure
Study 12169332 — Predictive Biomarker (PRD): CLN5 mRNA
Genes: CLN5
Study 9666940 — Surrogate Endpoint (SUR): Bone mineral density
Study 20974511 — Surrogate Endpoint (SUR): Blood pressure
Study 26160062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7490141 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2258874 — Surrogate Endpoint (SUR): Blood pressure
Study 27956016 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 26220945 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31145173 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31145173 — Surrogate Endpoint (SUR): Blood pressure
Study 30286558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22464581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15895275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9705036 — Surrogate Endpoint (SUR): Blood pressure
Study 31075662 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29078966 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 20072036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17919233 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 23684482 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 23684482 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 8553350 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21180216 — Surrogate Endpoint (SUR): Blood pressure
Study 15246912 — Surrogate Endpoint (SUR): Blood pressure
Study 15246912 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3289804 — Surrogate Endpoint (SUR): Serum creatinine
Study 23497111 — Surrogate Endpoint (SUR): Bone mineral density
Study 18343702 — Predictive Biomarker (PRD): FAM53B mRNA
Genes: FAM53B; KIAA0140; SMP
Study 9167019 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8193732 — Surrogate Endpoint (SUR): Blood pressure
Study 31350967 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 31350967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26179985 — Surrogate Endpoint (SUR): Blood pressure
Study 19061063 — Surrogate Endpoint (SUR): Blood pressure
Study 12091806 — Surrogate Endpoint (SUR): Blood pressure
Study 8946597 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 8946597 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30614153 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 23385306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20555369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20555369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20555369 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30868641 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 17974536 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12115318 — Safety Biomarker (SAF): Hyaluronic acid
Study 31685037 — Surrogate Endpoint (SUR): Blood pressure
Study 31544547 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 26011257 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29538682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29538682 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 14605954 — Predictive Biomarker (PRD): MFF mRNA
Genes: MFF; C2orf33; AD030; AD033; GL004
Study 10793494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10793494 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25837212 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25837212 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20012799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2189288 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 29799307 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 14963702 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14963702 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14963702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11588947 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9973671 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 9973671 — Surrogate Endpoint (SUR): Bone mineral density
Study 2647645 — Surrogate Endpoint (SUR): Blood pressure
Study 26465872 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 26465872 — Surrogate Endpoint (SUR): Blood pressure
Study 21786539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19190515 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 9268956 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31693128 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9628067 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9628067 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30998400 — Surrogate Endpoint (SUR): Blood pressure
Study 30998400 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28337880 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10719136 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28605557 — Surrogate Endpoint (SUR): Blood pressure
Study 26271344 — Predictive Biomarker (PRD): SLC22A1 mRNA
Genes: SLC22A1; OCT1
Study 23167843 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20019197 — Surrogate Endpoint (SUR): Blood pressure
Study 18657960 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18657960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16176140 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16176140 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10414119 — Predictive Biomarker (PRD): LTK mRNA
Genes: LTK; TYK1
Study 24759301 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24759301 — Surrogate Endpoint (SUR): Blood pressure
Study 16086615 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 7862469 — Surrogate Endpoint (SUR): Blood pressure
Study 30439786 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19247267 — Surrogate Endpoint (SUR): Blood pressure
Study 1532382 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 29968137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26401577 — Surrogate Endpoint (SUR): Bone mineral density
Study 14687524 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 31949012 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 20692602 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17985199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17985199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17985199 — Safety Biomarker (SAF): Interleukin 1
Study 10353670 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31834125 — Surrogate Endpoint (SUR): Blood pressure
Study 10993641 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 8366413 — Surrogate Endpoint (SUR): Blood pressure
Study 25498992 — Surrogate Endpoint (SUR): Blood pressure
Study 20031392 — Surrogate Endpoint (SUR): Bone mineral density
Study 23346948 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 16391584 — Surrogate Endpoint (SUR): Serum calcium
Study 9158047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9158047 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8198036 — Surrogate Endpoint (SUR): Blood pressure
Study 8198036 — Surrogate Endpoint (SUR): Serum uric acid
Study 30850828 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30850828 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17029616 — Monitoring Biomarker (MOI): HBV DNA
Study 7880659 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27041480 — Surrogate Endpoint (SUR): Blood pressure
Study 12941993 — Surrogate Endpoint (SUR): Blood pressure
Study 12941993 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8203335 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17225370 — Surrogate Endpoint (SUR): Blood pressure
Study 23619509 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23619509 — Safety Biomarker (SAF): BDNF
Study 16094059 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12108334 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8646822 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17367446 — Surrogate Endpoint (SUR): Serum testosterone
Study 26463007 — Surrogate Endpoint (SUR): Blood pressure
Study 25551810 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20724766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20724766 — Surrogate Endpoint (SUR): Blood pressure
Study 14568987 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 27354043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19841339 — Surrogate Endpoint (SUR): Blood pressure
Study 16766774 — Surrogate Endpoint (SUR): Bone mineral density
Study 16766774 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 18364384 — Surrogate Endpoint (SUR): Bone mineral density
Study 1774375 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26728913 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 22672707 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22672707 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 22672707 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8352699 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3669200 — Surrogate Endpoint (SUR): Blood pressure
Study 29738271 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 24122191 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24122191 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15465071 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 9509446 — Surrogate Endpoint (SUR): Serum creatinine
Study 24189367 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 19553647 — Predictive Biomarker (PRD): TCF3 mRNA
Genes: TCF3; BHLHB21; E2A; ITF1
Study 19553647 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 10789609 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10789609 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18412958 — Surrogate Endpoint (SUR): Blood pressure
Study 20722531 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 6851273 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17951625 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28845931 — Surrogate Endpoint (SUR): Sperm parameters
Study 25727806 — Surrogate Endpoint (SUR): Blood pressure
Study 24074879 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24074879 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 7932809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7932809 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27063478 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 20689824 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20689824 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 23593417 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 23593417 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 2455153 — Surrogate Endpoint (SUR): Blood pressure
Study 21998206 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 21998206 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 16549905 — Surrogate Endpoint (SUR): Serum creatinine
Study 10959787 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 2821151 — Surrogate Endpoint (SUR): Blood pressure
Study 29651953 — Surrogate Endpoint (SUR): Blood pressure
Study 14765284 — Surrogate Endpoint (SUR): Blood pressure
Study 12921618 — Surrogate Endpoint (SUR): Blood pressure
Study 16249145 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 2852389 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23549644 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 23549644 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 9039510 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 25790670 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study 25790670 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25790670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25790670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25790670 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25790670 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study 9643623 — Surrogate Endpoint (SUR): Blood pressure
Study 21577010 — Surrogate Endpoint (SUR): Blood pressure
Study 11273498 — Monitoring Biomarker (MOI): HBV DNA
Study 1394811 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 9833601 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30622317 — Surrogate Endpoint (SUR): Blood pressure
Study 21108204 — Surrogate Endpoint (SUR): Blood pressure
Study 15998354 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15998354 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9812915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9812915 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8043704 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29119418 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 28237959 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28237959 — Surrogate Endpoint (SUR): Blood pressure
Study 16834650 — Predictive Biomarker (PRD): SEPTIN3 mRNA
Genes: SEPTIN3; SEP3; SEPT3
Study 24669015 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 9930904 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28366648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7957533 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7957533 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24006155 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 24006155 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24006155 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8712823 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 30782904 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30782904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30782904 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 8018673 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31172415 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29090311 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study 26369563 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12404199 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12404199 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12404199 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7477219 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 354839 — Surrogate Endpoint (SUR): Blood pressure
Study 354839 — Surrogate Endpoint (SUR): Serum potassium
Study 28938961 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17846353 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 9487838 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25491026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25491026 — Surrogate Endpoint (SUR): Blood pressure
Study 25491026 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 14583179 — Surrogate Endpoint (SUR): Serum creatinine
Study 14583179 — Safety Biomarker (SAF): Urinary microalbumin
Study 24288364 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 16520442 — Surrogate Endpoint (SUR): Serum testosterone
Study 16520442 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16520442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9181906 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24906541 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22730929 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 22730929 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22730929 — Surrogate Endpoint (SUR): Bone mineral density
Study 14641801 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor delta
Genes: PPARD
Study 14641801 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14641801 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11053823 — Safety Biomarker (SAF): Interleukin 1
Study 11053823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2