TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27041692 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25291725 — Predictive Biomarker (PRD): CD200R1 mRNA
Genes: CD200R1; CD200R; CRTR2; MOX2R; OX2R; UNQ2522/PRO6015
Study 25291725 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 17356317 — Surrogate Endpoint (SUR): Blood pressure
Study 20035589 — Predictive Biomarker (PRD): ENPP2 mRNA
Genes: ENPP2; ATX; PDNP2
Study 17339106 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26426421 — Surrogate Endpoint (SUR): Blood pressure
Study 18824845 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18824845 — Surrogate Endpoint (SUR): Blood pressure
Study 11788126 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10091203 — Surrogate Endpoint (SUR): Bone mineral density
Study 2979255 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 29607623 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23538970 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 16553814 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16553814 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11002377 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1301850 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 30074934 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 24485481 — Predictive Biomarker (PRD): RIPK2 mRNA
Genes: RIPK2; CARDIAK; RICK; RIP2; UNQ277/PRO314/PRO34092
Study 24485481 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 27956398 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 11236522 — Surrogate Endpoint (SUR): Serum creatinine
Study 8142192 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30536713 — Surrogate Endpoint (SUR): Bone mineral density
Study 16733947 — Surrogate Endpoint (SUR): Blood pressure
Study 16941885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14550821 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20172900 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9552083 — Surrogate Endpoint (SUR): Bone mineral density
Study 17690160 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17690160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17690160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1362305 — Surrogate Endpoint (SUR): Blood pressure
Study 27116464 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27116464 — Surrogate Endpoint (SUR): Bone mineral density
Study 24508669 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 15642075 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15642075 — Surrogate Endpoint (SUR): Blood pressure
Study 15642075 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15055867 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9509440 — Surrogate Endpoint (SUR): Blood pressure
Study 28177908 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25541389 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 21398040 — Surrogate Endpoint (SUR): Blood pressure
Study 2475697 — Surrogate Endpoint (SUR): Blood pressure
Study 16872455 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 21770863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21770863 — Surrogate Endpoint (SUR): Serum uric acid
Study 19602608 — Surrogate Endpoint (SUR): Blood pressure
Study 14693584 — Surrogate Endpoint (SUR): Blood pressure
Study 9841599 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25319932 — Safety Biomarker (SAF): Hyaluronic acid
Study 19349547 — Surrogate Endpoint (SUR): Bone mineral density
Study 24140677 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 17373900 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26356162 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23368405 — Surrogate Endpoint (SUR): Blood pressure
Study 15040556 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 23483989 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19528363 — Surrogate Endpoint (SUR): Blood pressure
Study 17309405 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15529346 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15529346 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 15529346 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 15529346 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 8418715 — Surrogate Endpoint (SUR): Blood pressure
Study 11137410 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11137410 — Surrogate Endpoint (SUR): Blood pressure
Study 786681 — Surrogate Endpoint (SUR): Blood pressure
Study 786681 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 17590218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17590218 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23575965 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21354671 — Surrogate Endpoint (SUR): Blood pressure
Study 2285656 — Surrogate Endpoint (SUR): Blood pressure
Study 12077687 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12077687 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12077687 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8711268 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23857311 — Surrogate Endpoint (SUR): Blood pressure
Study 16728222 — Surrogate Endpoint (SUR): Serum creatinine
Study 11318052 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 7945476 — Surrogate Endpoint (SUR): Bone mineral density
Study 18192704 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15983453 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12028259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21528592 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 14752194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9780750 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 26376650 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 3342158 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30589098 — Surrogate Endpoint (SUR): Blood pressure
Study 24182325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24182325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12230022 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18929279 — Surrogate Endpoint (SUR): Blood pressure
Study 16369133 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 1452950 — Surrogate Endpoint (SUR): Bone mineral density
Study 22866996 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 14652238 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 1615900 — Surrogate Endpoint (SUR): Serum uric acid
Study 29991952 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 25491541 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 25491541 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 20016147 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1315827 — Surrogate Endpoint (SUR): Blood pressure
Study 1315827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1315827 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31041591 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31041591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20102728 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 16123321 — Surrogate Endpoint (SUR): Blood pressure
Study 10093648 — Surrogate Endpoint (SUR): Blood pressure
Study 7762503 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7762503 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7762503 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1969402 — Surrogate Endpoint (SUR): Blood pressure
Study 3283622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28456851 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 8721381 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25456561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25456561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16564941 — Surrogate Endpoint (SUR): Blood pressure
Study 8723851 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8723851 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25446228 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 23212802 — Predictive Biomarker (PRD): ESAM mRNA
Genes: ESAM; UNQ220/PRO246
Study 23212802 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23212802 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8389572 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 3538363 — Surrogate Endpoint (SUR): Blood pressure
Study 29661605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27455252 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 27455252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27455252 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17075123 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17075123 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 8813040 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27658890 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 27658890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27658890 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 23140112 — Surrogate Endpoint (SUR): Blood pressure
Study 21343146 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10733441 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8939323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26181088 — Surrogate Endpoint (SUR): Bone mineral density
Study 12801312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12801312 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10327874 — Surrogate Endpoint (SUR): Blood pressure
Study 7046930 — Surrogate Endpoint (SUR): Platelet count response
Study 28183335 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26843154 — Surrogate Endpoint (SUR): Blood pressure
Study 28106611 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24118794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25783756 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 23065509 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 18378519 — Surrogate Endpoint (SUR): Blood pressure
Study 18378519 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16360877 — Surrogate Endpoint (SUR): Blood pressure
Study 12745193 — Surrogate Endpoint (SUR): Blood pressure
Study 1627417 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 6744774 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31487806 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11860782 — Surrogate Endpoint (SUR): Blood pressure
Study 8861829 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1731046 — Surrogate Endpoint (SUR): Blood pressure
Study 3937219 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 3937219 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30586209 — Surrogate Endpoint (SUR): Blood pressure
Study 7751892 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30447958 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16459230 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26279111 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 20035686 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9728853 — Surrogate Endpoint (SUR): Blood pressure
Study 10707873 — Safety Biomarker (SAF): Interleukin 12
Study 10707873 — Monitoring Biomarker (MOI): HBV DNA
Study 10707873 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3259084 — Surrogate Endpoint (SUR): Blood pressure
Study 29532591 — Surrogate Endpoint (SUR): Serum creatinine
Study 21690510 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 21690510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21690510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17205943 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 14610642 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14610642 — Surrogate Endpoint (SUR): Bone mineral density
Study 14610642 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27841968 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22534479 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 20862935 — Surrogate Endpoint (SUR): Blood pressure
Study 10485271 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 1657084 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1657084 — Surrogate Endpoint (SUR): Blood pressure
Study 7866473 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31026244 — Surrogate Endpoint (SUR): Blood pressure
Study 24687684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24687684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24687684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24595149 — Surrogate Endpoint (SUR): Blood pressure
Study 20197484 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18806204 — Predictive Biomarker (PRD): BLOC1S2 mRNA
Genes: BLOC1S2; BLOS2; CEAP
Study 16894463 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 16894463 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 31203725 — Surrogate Endpoint (SUR): Blood pressure
Study 22580255 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17356080 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15754269 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15754269 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10425885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7558992 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25195684 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 18708192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3585610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31832876 — Surrogate Endpoint (SUR): Bacterial count
Study 31369185 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 31369185 — Predictive Biomarker (PRD): BMP4 mRNA
Genes: BMP4; BMP2B; DVR4
Study 31369185 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 31369185 — Surrogate Endpoint (SUR): Blood pressure
Study 23842215 — Surrogate Endpoint (SUR): Serum creatinine
Study 23842215 — Surrogate Endpoint (SUR): Serum sodium
Study 11451595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11451595 — Safety Biomarker (SAF): IL-6 and IL-10
Study 8295321 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23490655 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17578321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15489577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21225321 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15282660 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 20818902 — Surrogate Endpoint (SUR): Blood pressure
Study 20818902 — Surrogate Endpoint (SUR): Serum creatinine
Study 3895033 — Predictive Biomarker (PRD): UBC mRNA
Genes: UBC
Study 29975283 — Surrogate Endpoint (SUR): Blood pressure
Study 27450487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16188130 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 30315206 — Surrogate Endpoint (SUR): Bone mineral density
Study 26821042 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 23682639 — Surrogate Endpoint (SUR): Blood pressure
Study 22374335 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 22374335 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 22374335 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 8925829 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1336475 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31769496 — Surrogate Endpoint (SUR): Blood pressure
Study 28404155 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26132642 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 26132642 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26232779 — Predictive Biomarker (PRD): ADH1B mRNA
Genes: ADH1B; ADH2
Study 26232779 — Surrogate Endpoint (SUR): Blood pressure
Study 20380656 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31374049 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 25458464 — Safety Biomarker (SAF): Reactive oxygen species
Study 23620932 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16820564 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10828475 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8196571 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30993313 — Surrogate Endpoint (SUR): Blood pressure
Study 9864835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2197536 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24042256 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 19848195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19848195 — Surrogate Endpoint (SUR): Blood pressure
Study 19848195 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12165594 — Surrogate Endpoint (SUR): Blood pressure
Study 31485929 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 30587521 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2153193 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 29253068 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26484952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15914936 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 15914936 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8778155 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8778155 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 1330386 — Surrogate Endpoint (SUR): Blood pressure
Study 29071875 — Predictive Biomarker (PRD): SEPTIN6 mRNA
Genes: SEPTIN6; KIAA0128; SEP2; SEPT6
Study 29071875 — Predictive Biomarker (PRD): SEPTIN3 mRNA
Genes: SEPTIN3; SEP3; SEPT3
Study 21521341 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18773374 — Predictive Biomarker (PRD): F10 mRNA
Genes: F10
Study 18773374 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 18773374 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 10928254 — Surrogate Endpoint (SUR): Blood pressure
Study 12148181 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 3353893 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 31227535 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 19616494 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4