TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24293583 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 24293583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20716665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26414724 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23128664 — Surrogate Endpoint (SUR): Bone mineral density
Study 22540895 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11812555 — Surrogate Endpoint (SUR): Blood pressure
Study 17277392 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17277392 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17277392 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9363516 — Surrogate Endpoint (SUR): Blood pressure
Study 8239106 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3116985 — Surrogate Endpoint (SUR): Blood pressure
Study 31914878 — Surrogate Endpoint (SUR): Blood pressure
Study 31914878 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28130749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28130749 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28130749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19553142 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 19553142 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12832683 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12832683 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31218545 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27075909 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 22080632 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 22080632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19535971 — Surrogate Endpoint (SUR): Blood pressure
Study 12566894 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2363546 — Surrogate Endpoint (SUR): Blood pressure
Study 16410202 — Surrogate Endpoint (SUR): Blood pressure
Study 8998092 — Surrogate Endpoint (SUR): Blood pressure
Study 22447003 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22447003 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 22447003 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22447003 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22447003 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 22447003 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12865611 — Surrogate Endpoint (SUR): Blood pressure
Study 2423800 — Surrogate Endpoint (SUR): Blood pressure
Study 24420549 — Surrogate Endpoint (SUR): Blood pressure
Study 20872550 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17189550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17189550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10756219 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27578134 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 23013806 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAC mRNA
Genes: STAC; STAC1
Study 21964962 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 18569272 — Safety Biomarker (SAF): Hyaluronic acid
Study 8559480 — Surrogate Endpoint (SUR): Serum creatinine
Study 26188541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26188541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17196810 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 17196810 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 15201546 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15201546 — Surrogate Endpoint (SUR): Blood pressure
Study 29845723 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 21529363 — Surrogate Endpoint (SUR): Blood pressure
Study 6639916 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28272464 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 3330988 — Surrogate Endpoint (SUR): Blood pressure
Study 24002086 — Predictive Biomarker (PRD): IL11 mRNA
Genes: IL11
Study 24002086 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 31235374 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23076450 — Surrogate Endpoint (SUR): Blood pressure
Study 17086096 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17086096 — Surrogate Endpoint (SUR): Serum creatinine
Study 1977708 — Surrogate Endpoint (SUR): Blood pressure
Study 31472039 — Predictive Biomarker (PRD): DPP3 mRNA
Genes: DPP3
Study 29600897 — Surrogate Endpoint (SUR): Blood pressure
Study 28721700 — Surrogate Endpoint (SUR): Blood pressure
Study 8686047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1828764 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28235510 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25538263 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25538263 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 17612359 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 7362504 — Surrogate Endpoint (SUR): Blood pressure
Study 10208787 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7104154 — Surrogate Endpoint (SUR): Blood pressure
Study 20041911 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 11874817 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10232362 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31444972 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 31444972 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31444972 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 31444972 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 31444972 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28958110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8651549 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 6514178 — Surrogate Endpoint (SUR): Blood pressure
Study 24915052 — Surrogate Endpoint (SUR): Blood pressure
Study 22168345 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28370973 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28370973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28370973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23552127 — Surrogate Endpoint (SUR): Blood pressure
Study 27311415 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 16448252 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 29712745 — Surrogate Endpoint (SUR): Blood pressure
Study 29712745 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24144761 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17522607 — Surrogate Endpoint (SUR): Serum calcium
Study 17522607 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 17522607 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29423715 — Surrogate Endpoint (SUR): Bone mineral density
Study 24558403 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18410863 — Surrogate Endpoint (SUR): Blood pressure
Study 30431398 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20648661 — Surrogate Endpoint (SUR): Bone mineral density
Study 18931099 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27730665 — Predictive Biomarker (PRD): FPR2 mRNA
Genes: FPR2; FPRH1; FPRL1; LXA4R
Study 22963235 — Surrogate Endpoint (SUR): Blood pressure
Study 18339002 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18339002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10862229 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8180726 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8180726 — Surrogate Endpoint (SUR): Blood pressure
Study 18366445 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8641115 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8641115 — Safety Biomarker (SAF): Urinary microalbumin
Study 8641115 — Surrogate Endpoint (SUR): Blood pressure
Study 24729586 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 24729586 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 24729586 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 18476416 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14600850 — Surrogate Endpoint (SUR): Blood pressure
Study 29534465 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 31984623 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25233647 — Surrogate Endpoint (SUR): Serum creatinine
Study 19935427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19935427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19935427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19935427 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16883914 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8828744 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3933861 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 30385613 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30385613 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 28028723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28028723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28028723 — Safety Biomarker (SAF): Interleukin 1
Study 21742306 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 19919714 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 9416888 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3114203 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 24005959 — Surrogate Endpoint (SUR): Blood pressure
Study 24005959 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24005959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19131132 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18199394 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18199394 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 18199394 — Surrogate Endpoint (SUR): Blood pressure
Study 16893641 — Surrogate Endpoint (SUR): Pathological complete response
Study 11293237 — Surrogate Endpoint (SUR): Serum calcium
Study 11293237 — Surrogate Endpoint (SUR): Blood pressure
Study 1735313 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 28891198 — Surrogate Endpoint (SUR): Blood pressure
Study 28891198 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22490629 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 19436934 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17697904 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 15716194 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 8613305 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 17296530 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17296530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31178155 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28215362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28215362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21624226 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 9298736 — Monitoring Biomarker (MOI): HBV DNA
Study 31005204 — Surrogate Endpoint (SUR): Pathological complete response
Study 28656542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28656542 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 28656542 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 12636463 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10666187 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29215189 — Surrogate Endpoint (SUR): Blood pressure
Study 22424722 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31384902 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 10541047 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10541047 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 10541047 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10541047 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6433770 — Surrogate Endpoint (SUR): Blood pressure
Study 26545199 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 26545199 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 26845098 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 26845098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26845098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25418907 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16960445 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11476119 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 26284153 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17146380 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23660686 — Surrogate Endpoint (SUR): Blood pressure
Study 23660686 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8068604 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8068604 — Surrogate Endpoint (SUR): Blood pressure
Study 16331115 — Surrogate Endpoint (SUR): Blood pressure
Study 6237116 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 6237116 — Surrogate Endpoint (SUR): Serum testosterone
Study 29522979 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29522979 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 29522979 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 27305512 — Predictive Biomarker (PRD): CYBC1 mRNA
Genes: CYBC1; C17orf62; EROS
Study 2242520 — Surrogate Endpoint (SUR): Blood pressure
Study 16713391 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16713391 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16713391 — Surrogate Endpoint (SUR): Blood pressure
Study 15295409 — Surrogate Endpoint (SUR): Blood pressure
Study 27711918 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27711918 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18175748 — Safety Biomarker (SAF): Cytochrome c
Study 18175748 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17015053 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 12031821 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12031821 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24753036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17339868 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 17339868 — Surrogate Endpoint (SUR): Blood pressure
Study 23648946 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 23648946 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15356664 — Surrogate Endpoint (SUR): Blood pressure
Study 8304366 — Surrogate Endpoint (SUR): Blood pressure
Study 10658376 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 10658376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10658376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2128866 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 2128866 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28161147 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8044919 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8044919 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29705451 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29705451 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 29705451 — Surrogate Endpoint (SUR): Blood pressure
Study 26037429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26037429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15299060 — Predictive Biomarker (PRD): PCLO mRNA
Genes: PCLO; ACZ; KIAA0559
Study 8308936 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 22947269 — Surrogate Endpoint (SUR): Blood pressure
Study 12463319 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 12463319 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 7026255 — Surrogate Endpoint (SUR): Blood pressure
Study 30664267 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30664267 — Surrogate Endpoint (SUR): Serum creatinine
Study 31446143 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 8004358 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 2682593 — Surrogate Endpoint (SUR): Blood pressure
Study 23303873 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23303873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15078238 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 9271009 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28459069 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 10717781 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7075652 — Surrogate Endpoint (SUR): Blood pressure
Study 21449990 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16365183 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16365183 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 16365183 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12809966 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24552888 — Surrogate Endpoint (SUR): Blood pressure
Study 24552888 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11916781 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11916781 — Surrogate Endpoint (SUR): Blood pressure
Study 31262691 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9373733 — Predictive Biomarker (PRD): SMARCA2 mRNA
Genes: SMARCA2; BAF190B; BRM; SNF2A; SNF2L2
Study 18481113 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 31091754 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29300387 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 22234928 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22234928 — Predictive Biomarker (PRD): ZGPAT mRNA
Genes: ZGPAT; GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZIP
Study 17875084 — Monitoring Biomarker (MOI): HBV DNA
Study 10100994 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10100994 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31532959 — Surrogate Endpoint (SUR): Blood pressure
Study 31532959 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein