TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12528557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12528557 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9694306 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31493177 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31493177 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 14530859 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 14530859 — Surrogate Endpoint (SUR): Blood pressure
Study 8774208 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29029210 — Surrogate Endpoint (SUR): Serum uric acid
Study 29029210 — Surrogate Endpoint (SUR): Serum creatinine
Study 15010181 — Surrogate Endpoint (SUR): Blood pressure
Study 11181149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11181149 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3346069 — Surrogate Endpoint (SUR): Blood pressure
Study 26308227 — Surrogate Endpoint (SUR): Bone mineral density
Study 23613825 — Safety Biomarker (SAF): Reactive oxygen species
Study 11468228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25773554 — Predictive Biomarker (PRD): RIT1 mRNA
Genes: RIT1; RIBB; RIT; ROC1
Study 15840666 — Surrogate Endpoint (SUR): Serum creatinine
Study 17492425 — Safety Biomarker (SAF): Cytochrome c
Study 15726874 — Surrogate Endpoint (SUR): Blood pressure
Study 9678319 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 1883120 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1883120 — Surrogate Endpoint (SUR): Blood pressure
Study 1883120 — Surrogate Endpoint (SUR): Serum creatinine
Study 31085814 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31085814 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 31085814 — Surrogate Endpoint (SUR): Bone mineral density
Study 31725608 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31725608 — Surrogate Endpoint (SUR): Blood pressure
Study 21530213 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18603947 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 8703450 — Surrogate Endpoint (SUR): Blood pressure
Study 28965100 — Safety Biomarker (SAF): Hyaluronic acid
Study 29668352 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 25054390 — Surrogate Endpoint (SUR): Blood pressure
Study 20079572 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 12798894 — Safety Biomarker (SAF): Hyaluronic acid
Study 8770965 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8770965 — Surrogate Endpoint (SUR): Blood pressure
Study 1628410 — Surrogate Endpoint (SUR): Blood pressure
Study 31606364 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31606364 — Surrogate Endpoint (SUR): Serum potassium
Study 30307304 — Surrogate Endpoint (SUR): Blood pressure
Study 25228130 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 22410137 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 19111163 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 30851630 — Predictive Biomarker (PRD): SLC52A2 mRNA
Genes: SLC52A2; GPR172A; PAR1; RFT3
Study 30851630 — Predictive Biomarker (PRD): F2RL3 mRNA
Genes: F2RL3; PAR4
Study 15593389 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 3877288 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15892618 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15892618 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 15892618 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 15892618 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27278926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27278926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27278926 — Surrogate Endpoint (SUR): Blood pressure
Study 27278926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27278926 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19084376 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19084376 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19084376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22178004 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 22178004 — Surrogate Endpoint (SUR): Blood pressure
Study 15956124 — Surrogate Endpoint (SUR): Blood pressure
Study 9426846 — Surrogate Endpoint (SUR): Serum calcium
Study 3886399 — Surrogate Endpoint (SUR): Blood pressure
Study 19892663 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19892663 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19892663 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19892663 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 19892663 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 10932333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20688462 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24641841 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23394502 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20423844 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 22552800 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 14513268 — Surrogate Endpoint (SUR): Bone mineral density
Study 2256863 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25637340 — Predictive Biomarker (PRD): Hormone receptor
Study 24629635 — Predictive Biomarker (PRD): PSME1 mRNA
Genes: PSME1; IFI5111
Study 24629635 — Predictive Biomarker (PRD): ECM1 mRNA
Genes: ECM1
Study 24629635 — Predictive Biomarker (PRD): YES1 mRNA
Genes: YES1; YES
Study 24629635 — Predictive Biomarker (PRD): BGN mRNA
Genes: BGN; SLRR1A
Study 24629635 — Predictive Biomarker (PRD): CNDP1 mRNA
Genes: CNDP1; CN1; CPGL2; UNQ1915/PRO4380
Study 24629635 — Predictive Biomarker (PRD): MRC2 mRNA
Genes: MRC2; CLEC13E; ENDO180; KIAA0709; UPARAP
Study 24629635 — Predictive Biomarker (PRD): ADAM9 mRNA
Genes: ADAM9; KIAA0021; MCMP; MDC9; MLTNG
Study 24629635 — Predictive Biomarker (PRD): CDON mRNA
Genes: CDON; CDO
Study 24629635 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 15005721 — Predictive Biomarker (PRD): RAB3A mRNA
Genes: RAB3A
Study 11307656 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 30954360 — Surrogate Endpoint (SUR): Blood pressure
Study 19366489 — Safety Biomarker (SAF): DRD2
Study 7945622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7945622 — Safety Biomarker (SAF): Interleukin 1
Study 7945622 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 7945622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7945622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30922297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30922297 — Surrogate Endpoint (SUR): Blood pressure
Study 29362371 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28077531 — Surrogate Endpoint (SUR): Serum creatinine
Study 22380717 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 22380717 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 22380717 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15920008 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9893189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9893189 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21678095 — Predictive Biomarker (PRD): MAVS mRNA
Genes: MAVS; IPS1; KIAA1271; VISA
Study 17716550 — Surrogate Endpoint (SUR): Blood pressure
Study 15800139 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10385578 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 8723144 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 6805588 — Surrogate Endpoint (SUR): Blood pressure
Study 31907776 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 31764099 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28294173 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28294173 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28294173 — Surrogate Endpoint (SUR): Blood pressure
Study 22568828 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15080865 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 9284696 — Surrogate Endpoint (SUR): Bone mineral density
Study 21302490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17967831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18603575 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 15860983 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15860983 — Surrogate Endpoint (SUR): Blood pressure
Study 15860983 — Safety Biomarker (SAF): Urinary microalbumin
Study 1880885 — Surrogate Endpoint (SUR): Blood pressure
Study 30762760 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25326074 — Surrogate Endpoint (SUR): Blood pressure
Study 11693763 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11693763 — Surrogate Endpoint (SUR): Blood pressure
Study 27058904 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12675669 — Predictive Biomarker (PRD): GSN mRNA
Genes: GSN
Study 9588444 — Predictive Biomarker (PRD): PTPRN mRNA
Genes: PTPRN; ICA3; ICA512
Study 2644342 — Surrogate Endpoint (SUR): Blood pressure
Study 28619301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28619301 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 21722499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31242333 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 28667207 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 26137844 — Surrogate Endpoint (SUR): Blood pressure
Study 24065808 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 16784972 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16784972 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11245352 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 9399606 — Surrogate Endpoint (SUR): Blood pressure
Study 22275399 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20737140 — Surrogate Endpoint (SUR): Bone mineral density
Study 2899510 — Surrogate Endpoint (SUR): Blood pressure
Study 23299761 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 23299761 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 15311098 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15311098 — Surrogate Endpoint (SUR): Blood pressure
Study 8151265 — Surrogate Endpoint (SUR): Blood pressure
Study 8151265 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8151265 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8151265 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8151265 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26319283 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 19321009 — Surrogate Endpoint (SUR): Blood pressure
Study 11470718 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21471141 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17051589 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17051589 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 17051589 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1888787 — Surrogate Endpoint (SUR): Blood pressure
Study 19356104 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19356104 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 8624772 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8624772 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16181532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16181532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8758013 — Surrogate Endpoint (SUR): Blood pressure
Study 31806021 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 26211605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8187316 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8187316 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8187316 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21293249 — Surrogate Endpoint (SUR): Serum creatinine
Study 19878577 — Surrogate Endpoint (SUR): Serum creatinine
Study 19878577 — Surrogate Endpoint (SUR): Blood pressure
Study 14687095 — Surrogate Endpoint (SUR): Blood pressure
Study 29562405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29562405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29562405 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 29562405 — Safety Biomarker (SAF): Interleukin 1
Study 23425543 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 21274861 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 31912523 — Surrogate Endpoint (SUR): Probing pocket depth
Study 6813484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28229508 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 8527353 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8527353 — Surrogate Endpoint (SUR): Blood pressure
Study 2689045 — Surrogate Endpoint (SUR): Blood pressure
Study 26314451 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 26314451 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 26314451 — Safety Biomarker (SAF): Cytochrome c
Study 17139433 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2870944 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 25132122 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 2744799 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25616927 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 23505929 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 14653030 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14653030 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11096046 — Surrogate Endpoint (SUR): Serum creatinine
Study 8445223 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16410734 — Surrogate Endpoint (SUR): Blood pressure
Study 16410734 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9332329 — Surrogate Endpoint (SUR): Serum creatinine
Study 3094063 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20299628 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1961958 — Surrogate Endpoint (SUR): Blood pressure
Study 6789294 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 24462012 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24462012 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17356966 — Surrogate Endpoint (SUR): Bone mineral density
Study 16332659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16332659 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16332659 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16332659 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16332659 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 16332659 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 28339738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28339738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29664836 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25343949 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19037576 — Safety Biomarker (SAF): MTHFR
Study 19037576 — Surrogate Endpoint (SUR): Bone mineral density
Study 17917504 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 17917504 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15389230 — Surrogate Endpoint (SUR): Blood pressure
Study 7972616 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15769986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15769986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10406153 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24937643 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24937643 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10467325 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29677190 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 8757525 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8757525 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 8757525 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8757525 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 8757525 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 29231452 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22876438 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 22876438 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 22876438 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22876438 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22876438 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22876438 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22876438 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 22876438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10378706 — Safety Biomarker (SAF): Reactive oxygen species
Study 10378706 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26471114 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 22243494 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 12444178 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10349300 — Safety Biomarker (SAF): Reactive oxygen species
Study 25147079 — Surrogate Endpoint (SUR): Blood pressure
Study 8721128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8721128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8721128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8721128 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17582439 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11575336 — Surrogate Endpoint (SUR): Blood pressure
Study 165913 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 26537980 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 1934866 — Surrogate Endpoint (SUR): Blood pressure
Study 6360415 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6360415 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1742915 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 7096149 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26857391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2