TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02611973 — Surrogate Endpoint (SUR): Hematologic response
Study NCT01406548 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT06243679 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00001568 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04185012 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study NCT02584946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00321789 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02681198 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01519700 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT03356626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03151629 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02121301 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT00713440 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01002846 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02304939 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00928902 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01300234 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02662348 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02662348 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01762501 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04247217 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01912560 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT01912560 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01912560 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02381730 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00731809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02593175 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04227015 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04940429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04940429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04940429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00841334 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02016638 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03814707 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03042117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04307004 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03661112 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04280341 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04280341 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03250637 — Predictive Biomarker (PRD): TLR1 mRNA
Genes: TLR1; KIAA0012
Study NCT03250637 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study NCT03250637 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT03250637 — Predictive Biomarker (PRD): TLR10 mRNA
Genes: TLR10; UNQ315/PRO358
Study NCT01543932 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00763412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00324675 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00475670 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04128137 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02111473 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01421186 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT00802152 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04483505 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT04483505 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03451682 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT03451682 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03451682 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04051736 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04801147 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT04121065 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT04121065 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01998425 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT00528645 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT04759235 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study NCT00560118 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT01530776 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00946231 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01893281 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02819830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02819830 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03461276 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study NCT03406780 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01425424 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01644279 — Predictive Biomarker (PRD): AIFM1 mRNA
Genes: AIFM1; AIF; PDCD8
Study NCT01177579 — Safety Biomarker (SAF): Cytochrome c
Study NCT01177579 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT00267839 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01096277 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01096277 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00485758 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04458155 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT02596165 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04379726 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04085419 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04595825 — Predictive Biomarker (PRD): CCL24 mRNA
Genes: CCL24; MPIF2; SCYA24
Study NCT01753687 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT04569877 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02291081 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02291081 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02876276 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00355147 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02549391 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT00503750 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04661241 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT01478672 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03834766 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study NCT04435210 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04026828 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04439136 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01582685 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00248495 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT00248495 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT03812380 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01512199 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02986282 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02302768 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02302768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02637570 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00657202 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00657202 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00657202 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04675502 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03724877 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT01741896 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03961685 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study NCT00660764 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00660764 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06106932 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06106932 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT01448187 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00432146 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study NCT02533596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02189538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03091374 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00390741 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02902874 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03494231 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT03494231 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02728115 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00569673 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01858116 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03500913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03583554 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT03934398 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01009580 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01575652 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03599206 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT03599206 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study NCT01692028 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02830113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02455154 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02738008 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study NCT01092728 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01015859 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT00443144 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study NCT00443144 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00100451 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02972060 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT02198365 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03481101 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04619329 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT00093587 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00826254 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01830608 — Predictive Biomarker (PRD): HTRA1 mRNA
Genes: HTRA1; HTRA; PRSS11
Study NCT01830608 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00484289 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01418638 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01418638 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01418638 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00680901 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03062579 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT03918616 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT00339456 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02477319 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01859273 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03798106 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT03798106 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT00549692 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02849977 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study NCT02849977 — Predictive Biomarker (PRD): PCSK1 mRNA
Genes: PCSK1; NEC1
Study NCT03755414 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT04786327 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT03745287 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03745287 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02248298 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT03636282 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01964495 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01964495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00000547 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04144348 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00809419 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00809419 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00239343 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00239343 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00007345 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT00007345 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT05747053 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT05747053 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT03095690 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04219579 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT02579499 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00677326 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00677326 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00677326 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT02749435 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03453489 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study NCT01528176 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01172223 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03805620 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03805620 — Safety Biomarker (SAF): BDNF
Study NCT03094260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03140514 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT02566343 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03744208 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03353675 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05183308 — Surrogate Endpoint (SUR): Serum calcium
Study NCT05183308 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03242876 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03778931 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03778931 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03195192 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03195192 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study NCT02078557 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02078557 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02666950 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study NCT01634880 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01634880 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03397732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT03615144 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03615144 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00905892 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03678909 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01769508 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02814201 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04206033 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT04206033 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT04206033 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study NCT04206033 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT04206033 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study NCT04206033 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT04206033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04206033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03598270 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01041638 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02723526 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT01008371 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT00694603 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00694603 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03191773 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02369380 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00657345 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03085615 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03085615 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02291146 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01863576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03522298 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03522298 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT02883231 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT01506609 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01506609 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT00327496 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02191267 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01739946 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04001270 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study NCT05407649 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04379596 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02741622 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT06434896 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02831764 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03449758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04641871 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT03983603 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03983603 — Safety Biomarker (SAF): Th2 cell
Study NCT02537821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02537821 — Monitoring Biomarker (MOI): Procalcitonin