TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02616133 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00717405 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00717405 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02195050 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02195050 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT02195050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04613258 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT00023010 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study NCT00023010 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study NCT01195350 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02437578 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT02437578 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study NCT02437578 — Predictive Biomarker (PRD): CYP27A1 mRNA
Genes: CYP27A1; CYP27
Study NCT02437578 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study NCT02437578 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study NCT00035581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01328639 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00410865 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01279902 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01223820 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study NCT01223820 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT01223820 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04507230 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00469417 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT02530905 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02077634 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04109521 — Surrogate Endpoint (SUR): Bacterial count
Study NCT01163825 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02495415 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT01639092 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02482090 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05203562 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study NCT01272297 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01615198 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04023539 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00081848 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00081848 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03721068 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study NCT02060760 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT00731744 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study NCT00731744 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00731744 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00731744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00731744 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00731744 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT00444847 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02128386 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03858777 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT03858777 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02187822 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study NCT01940341 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03459807 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00359281 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03782779 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00407147 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03359434 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02970994 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT02647177 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02309528 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01060618 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT03500120 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study NCT02730845 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03041025 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study NCT04591717 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03805815 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00498836 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT02364453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01820208 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01667627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02146118 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02146118 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01942655 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01942655 — Safety Biomarker (SAF): Interleukin 12
Study NCT00186680 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00997243 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study NCT03841344 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03841344 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT00276133 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02949518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03968601 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT00196651 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03848286 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study NCT01980823 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT01066143 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02095782 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01175018 — Safety Biomarker (SAF): Interleukin 1
Study NCT04126525 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04583319 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00911235 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02788240 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT02788240 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03611608 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study NCT02486510 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT01195779 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04688346 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01542359 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03671538 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03671538 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03671538 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04318964 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT03374111 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT02790762 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00801164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00801164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01541709 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT04295174 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01163162 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02785393 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02075866 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02608177 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04473105 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01244620 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01244620 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02496494 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03218254 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT02325726 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT03423680 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02059772 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00131560 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02522338 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT02342587 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00825123 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03722212 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study NCT00685477 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT02682563 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02682563 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01332864 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03430869 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04058080 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00678717 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00858793 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00858793 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01948414 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT01948414 — Safety Biomarker (SAF): DRD2
Study NCT03514420 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study NCT01762579 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study NCT05492279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03347435 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03347435 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT03468764 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00965185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00377416 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00059306 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03066388 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00179829 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT01065818 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT04437771 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04437771 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study NCT01559428 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT03225547 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03225547 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00707408 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04817904 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study NCT04817904 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05612724 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01125137 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study NCT01125137 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study NCT01507129 — Predictive Biomarker (PRD): UCN2 mRNA
Genes: UCN2; SRP; URP
Study NCT00217282 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03283137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01853657 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03215693 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02902991 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02612298 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03325426 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00939718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02045563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00019812 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03161405 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00264394 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00969943 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT02096991 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00005591 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04513587 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02544386 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01082926 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00748072 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT01931007 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03097107 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03185455 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04087343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02623036 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02623036 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03473743 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT01503736 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03290326 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00283894 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT00283894 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study NCT03092752 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05093491 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03666728 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03666728 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03666728 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04277390 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT03930810 — Predictive Biomarker (PRD): ATP8B1 mRNA
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study NCT03930810 — Predictive Biomarker (PRD): ABCB4 mRNA
Genes: ABCB4; MDR3; PGY3
Study NCT03930810 — Predictive Biomarker (PRD): TJP2 mRNA
Genes: TJP2; X104; ZO2
Study NCT01594203 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT02155582 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01027923 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT02437760 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT00904215 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03681080 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study NCT03232619 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00904423 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04546074 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT00280644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03214276 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03214276 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03194139 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01773590 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01015326 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01015326 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01833767 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03396120 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03280394 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02256722 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT06264193 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06264193 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03289962 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03059966 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT03059966 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03059966 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT03059966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03059966 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00276926 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT00276926 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study NCT00276926 — Predictive Biomarker (PRD): HIP1 mRNA
Genes: HIP1
Study NCT01844674 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT05621694 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04032119 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study NCT03719898 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01442974 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT04438239 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04309981 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04309981 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT01289717 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00019591 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00689819 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02562378 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02025192 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02995005 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00367861 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT00622414 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00327379 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT03098680 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01028703 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03883685 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT03883685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04155294 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03227497 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01344707 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT00961207 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02319590 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT02319590 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study NCT00365846 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT03682341 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study NCT03511248 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02997202 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02886247 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT00820586 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00866736 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00866736 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03841266 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03175497 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03175497 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01041222 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03592888 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03592888 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01887652 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT06395194 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02810886 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04044261 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study NCT01855685 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00738049 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT04486794 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00059033 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03921736 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03921736 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02849691 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05387616 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K