TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19671655 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 19671655 — Surrogate Endpoint (SUR): Bone mineral density
Study 16280694 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12160199 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12160199 — Surrogate Endpoint (SUR): Blood pressure
Study 24842200 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 24842200 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31053082 — Surrogate Endpoint (SUR): Blood pressure
Study 27919453 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9719328 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 7695416 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 14504877 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1514346 — Surrogate Endpoint (SUR): Serum potassium
Study 30059487 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30059487 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23948830 — Surrogate Endpoint (SUR): Bone mineral density
Study 20306017 — Surrogate Endpoint (SUR): Bone mineral density
Study 24630505 — Monitoring Biomarker (MOI): HBV DNA
Study 23420550 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23420550 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 12477508 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12477508 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12477508 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 6103766 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 17164234 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 10208393 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10208393 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 10208393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10208393 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7829619 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 7829619 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31993781 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21331055 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 21331055 — Surrogate Endpoint (SUR): Blood pressure
Study 31660654 — Predictive Biomarker (PRD): PRKN mRNA
Genes: PRKN; PARK2
Study 31660654 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 31660654 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study 31660654 — Predictive Biomarker (PRD): KANSL1 mRNA
Genes: KANSL1; CENP-36; KIAA1267; MSL1V1; NSL1
Study 31660654 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31660654 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 25604313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25604313 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25604313 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 25604313 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 25604313 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 25604313 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 14676650 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 11967819 — Surrogate Endpoint (SUR): Serum creatinine
Study 3429696 — Surrogate Endpoint (SUR): Blood pressure
Study 27371106 — Surrogate Endpoint (SUR): Blood pressure
Study 16123483 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1610589 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16302004 — Surrogate Endpoint (SUR): Blood pressure
Study 7843440 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1334803 — Surrogate Endpoint (SUR): Blood pressure
Study 6502311 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28524039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28524039 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15307012 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7506324 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 7506324 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7506324 — Surrogate Endpoint (SUR): Blood pressure
Study 8912763 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27701370 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 26934294 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 24251724 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 23010601 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18226292 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15298982 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15298982 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 15298982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7753268 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20031767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9562003 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8148354 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25835443 — Surrogate Endpoint (SUR): Blood pressure
Study 9396415 — Surrogate Endpoint (SUR): Blood pressure
Study 1286654 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1286654 — Surrogate Endpoint (SUR): Blood pressure
Study 18394014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18394014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18394014 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18394014 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18394014 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18394014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16166814 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 14618037 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 1394348 — Surrogate Endpoint (SUR): Blood pressure
Study 26260784 — Surrogate Endpoint (SUR): Bone mineral density
Study 8775589 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 24333069 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 19615131 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19615131 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 19615131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15177700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9521635 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 8113849 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 30110103 — Surrogate Endpoint (SUR): Blood pressure
Study 25619124 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12697482 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10321416 — Surrogate Endpoint (SUR): Blood pressure
Study 8793457 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30018129 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 28193605 — Surrogate Endpoint (SUR): Blood pressure
Study 26178726 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26178726 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26178726 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26178726 — Predictive Biomarker (PRD): GPR119 mRNA
Genes: GPR119
Study 9175299 — Safety Biomarker (SAF): Hyaluronic acid
Study 3007162 — Surrogate Endpoint (SUR): Blood pressure
Study 3007162 — Surrogate Endpoint (SUR): Serum potassium
Study 26690262 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 26690262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20669669 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 20669669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20669669 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20669669 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12846768 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 4028963 — Surrogate Endpoint (SUR): Blood pressure
Study 27143183 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30713721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29980989 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 20541828 — Surrogate Endpoint (SUR): Serum creatinine
Study 16969498 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16969498 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11240946 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27082782 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 24989946 — Surrogate Endpoint (SUR): Blood pressure
Study 22156609 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 12621276 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 1961960 — Surrogate Endpoint (SUR): Blood pressure
Study 25396266 — Surrogate Endpoint (SUR): Bone mineral density
Study 25396266 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25396266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24117666 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 27914241 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 15292668 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11698326 — Surrogate Endpoint (SUR): Blood pressure
Study 9150314 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 9150314 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 9150314 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26790216 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 18234557 — Surrogate Endpoint (SUR): Blood pressure
Study 1899206 — Surrogate Endpoint (SUR): Blood pressure
Study 26747051 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 21126389 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 21126389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23500254 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21326075 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25956209 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 25956209 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25956209 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 20225606 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 18493166 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28733430 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23424061 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 19840477 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17145229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17145229 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17145229 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10709776 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10709776 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 10709776 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10709776 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31668787 — Surrogate Endpoint (SUR): Blood pressure
Study 18458907 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 8925110 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 6507309 — Surrogate Endpoint (SUR): Blood pressure
Study 21952978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14624915 — Surrogate Endpoint (SUR): Serum testosterone
Study 10989239 — Surrogate Endpoint (SUR): Bone mineral density
Study 24472665 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24472665 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24472665 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 16510462 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8626832 — Surrogate Endpoint (SUR): Plasma testosterone level
Study 24284387 — Surrogate Endpoint (SUR): Blood pressure
Study 12014417 — Surrogate Endpoint (SUR): Blood pressure
Study 8977745 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1334465 — Surrogate Endpoint (SUR): Blood pressure
Study 27654971 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27654971 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27654971 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 25034315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17727981 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 11703619 — Surrogate Endpoint (SUR): Serum creatinine
Study 11703619 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28969626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28969626 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 28969626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25277305 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21744187 — Surrogate Endpoint (SUR): Blood pressure
Study 16112244 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11783600 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9129478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 30392341 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11933558 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2405089 — Surrogate Endpoint (SUR): Blood pressure
Study 2405089 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30335191 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29128712 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 16376765 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20074703 — Surrogate Endpoint (SUR): Blood pressure
Study 17628683 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17628683 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9117191 — Predictive Biomarker (PRD): ALAD mRNA
Genes: ALAD
Study 19460503 — Surrogate Endpoint (SUR): Serum creatinine
Study 28768651 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28768651 — Surrogate Endpoint (SUR): Bone mineral density
Study 23983256 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 11411907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1968000 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1968000 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22340231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22340231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1551352 — Surrogate Endpoint (SUR): Blood pressure
Study 29854081 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 7664856 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1011296 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 25958714 — Surrogate Endpoint (SUR): Blood pressure
Study 3537784 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26228998 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26228998 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 15271690 — Surrogate Endpoint (SUR): Serum testosterone
Study 2092965 — Surrogate Endpoint (SUR): Blood pressure
Study 16127194 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 27770338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27770338 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 27770338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17966440 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9380326 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 29262978 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 26056164 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 22716279 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 22716279 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 22716279 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 8884758 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 8884758 — Surrogate Endpoint (SUR): Blood pressure
Study 30419927 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 27468953 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27468953 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 26852497 — Surrogate Endpoint (SUR): Blood pressure
Study 21722684 — Monitoring Biomarker (MOI): HBV DNA
Study 12673785 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26075288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26075288 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16420563 — Safety Biomarker (SAF): MTHFR
Study 16420563 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 16420563 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 16420563 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 14693301 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14693301 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24853781 — Surrogate Endpoint (SUR): Blood pressure
Study 22153787 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 18594928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12902100 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 12902100 — Surrogate Endpoint (SUR): Blood pressure
Study 10578215 — Surrogate Endpoint (SUR): Blood pressure
Study 8678389 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 8678389 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20413453 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17418849 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15353497 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27583368 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20060082 — Surrogate Endpoint (SUR): Bone mineral density
Study 10416910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2205455 — Safety Biomarker (SAF): L-acetylcarnitine
Study 29265039 — Surrogate Endpoint (SUR): Serum creatinine
Study 11411623 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 3146539 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15023613 — Surrogate Endpoint (SUR): Blood pressure
Study 15129595 — Surrogate Endpoint (SUR): Blood pressure
Study 28376188 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18467719 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16331117 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16331117 — Surrogate Endpoint (SUR): Blood pressure
Study 10885420 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 8772550 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26295176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12441015 — Surrogate Endpoint (SUR): Blood pressure
Study 7587747 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29936455 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29936455 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29936455 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein