TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10749610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10749610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10749610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1311648 — Surrogate Endpoint (SUR): Blood pressure
Study 3004088 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17478034 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15620433 — Surrogate Endpoint (SUR): Blood pressure
Study 10623334 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31520895 — Surrogate Endpoint (SUR): Blood pressure
Study 31520895 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25681448 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 28885365 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23266209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19548163 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15157730 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25623388 — Surrogate Endpoint (SUR): Blood pressure
Study 8610768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28400191 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28400191 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 28400191 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28400191 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27573561 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 8562272 — Surrogate Endpoint (SUR): Blood pressure
Study 17826318 — Surrogate Endpoint (SUR): Blood pressure
Study 9589523 — Surrogate Endpoint (SUR): Forced vital capacity
Study 174388 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12939417 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8822590 — Surrogate Endpoint (SUR): Blood pressure
Study 8822590 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24749369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24749369 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24749369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 16132903 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20854047 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9719052 — Surrogate Endpoint (SUR): Blood pressure
Study 28013387 — Surrogate Endpoint (SUR): Blood pressure
Study 28181973 — Surrogate Endpoint (SUR): Blood pressure
Study 19161365 — Surrogate Endpoint (SUR): Blood pressure
Study 8905422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8905422 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 8905422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8905422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17012878 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 21697609 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 21697609 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16352669 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16352669 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 16352669 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 16352669 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 27328952 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 27328952 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 27328952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27328952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27328952 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27328952 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 31358022 — Surrogate Endpoint (SUR): Blood pressure
Study 19922897 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 19922897 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 7513171 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 7513171 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7513171 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 7513171 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 7513171 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7513171 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7513171 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 30012812 — Surrogate Endpoint (SUR): Blood pressure
Study 12906976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1682735 — Predictive Biomarker (PRD): TNFRSF25 mRNA
Genes: TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; UNQ455/PRO779
Study 7438470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DAND5 mRNA
Genes: DAND5; CER2; CKTSF1B3; GREM3; SP1
Study 28646140 — Surrogate Endpoint (SUR): Blood pressure
Study 28646140 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28646140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28646140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28646140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19713649 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7687978 — Monitoring Biomarker (MOI): HBV DNA
Study 7687978 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15574076 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15574076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15574076 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15574076 — Safety Biomarker (SAF): IL-6 and IL-10
Study 9143733 — Predictive Biomarker (PRD): Microsatellite instability
Study 20706875 — Surrogate Endpoint (SUR): Blood pressure
Study 15919462 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15919462 — Surrogate Endpoint (SUR): Serum creatinine
Study 15215814 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26193126 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23866782 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 18491582 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18491582 — Surrogate Endpoint (SUR): Blood pressure
Study 11221291 — Surrogate Endpoint (SUR): Blood pressure
Study 8706770 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21131223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21131223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21131223 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19187079 — Surrogate Endpoint (SUR): Serum creatinine
Study 17105798 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17105798 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17105798 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17105798 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 17105798 — Surrogate Endpoint (SUR): Serum testosterone
Study 17105798 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 28917374 — Surrogate Endpoint (SUR): Blood pressure
Study 9718538 — Surrogate Endpoint (SUR): Bone mineral density
Study 9718538 — Surrogate Endpoint (SUR): Serum calcium
Study 7664364 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29784554 — Surrogate Endpoint (SUR): Serum creatinine
Study 29784554 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27456464 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 23053340 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12663594 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 12663594 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15734619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15734619 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12783075 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8848472 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 29279527 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8951590 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8951590 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16096860 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10414910 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10414910 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20599292 — Safety Biomarker (SAF): Interleukin 12
Study 20599292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16235180 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12442196 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8147340 — Surrogate Endpoint (SUR): Blood pressure
Study 29189290 — Surrogate Endpoint (SUR): Blood pressure
Study 22431578 — Surrogate Endpoint (SUR): Serum potassium
Study 6140239 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 23088844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25819061 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21852106 — Surrogate Endpoint (SUR): Blood pressure
Study 19081767 — Surrogate Endpoint (SUR): Blood pressure
Study 19081767 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19081767 — Surrogate Endpoint (SUR): Serum creatinine
Study 11433695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31092548 — Predictive Biomarker (PRD): ADCY10 mRNA
Genes: ADCY10; SAC
Study 31092548 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31092548 — Surrogate Endpoint (SUR): Blood pressure
Study 6405770 — Surrogate Endpoint (SUR): Blood pressure
Study 3800816 — Surrogate Endpoint (SUR): Blood pressure
Study 23412547 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 16368318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19092257 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19092257 — Surrogate Endpoint (SUR): Blood pressure
Study 10825058 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22738922 — Surrogate Endpoint (SUR): Blood pressure
Study 18716400 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15093201 — Surrogate Endpoint (SUR): Pathological complete response
Study 11477860 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11477860 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7829908 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 20061426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20061426 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11901047 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28122895 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21867445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21867445 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9787863 — Surrogate Endpoint (SUR): Blood pressure
Study 23283356 — Surrogate Endpoint (SUR): Blood pressure
Study 14718699 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9222948 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25861621 — Surrogate Endpoint (SUR): Serum calcium
Study 23327199 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 3126122 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30016450 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 23949898 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21666445 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8622596 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1315645 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1315645 — Surrogate Endpoint (SUR): Blood pressure
Study 17852431 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12103383 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28628374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28628374 — Surrogate Endpoint (SUR): Bone mineral density
Study 16356804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16356804 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 390811 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30968431 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 30968431 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 23736997 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23736997 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19002087 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19002087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19002087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22512878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17943348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9095813 — Surrogate Endpoint (SUR): Serum creatinine
Study 29945203 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 22244829 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 16202678 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 16202678 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16202678 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 11856128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10432408 — Surrogate Endpoint (SUR): Blood pressure
Study 28241420 — Surrogate Endpoint (SUR): Bone mineral density
Study 25788034 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 19903804 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28338531 — Predictive Biomarker (PRD): PCLO mRNA
Genes: PCLO; ACZ; KIAA0559
Study 27353769 — Safety Biomarker (SAF): Hyaluronic acid
Study 19861864 — Surrogate Endpoint (SUR): Serum potassium
Study 11207993 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 25526373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25526373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23289919 — Surrogate Endpoint (SUR): Blood pressure
Study 17137514 — Surrogate Endpoint (SUR): Bone mineral density
Study 10872704 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23277436 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 19042325 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 2878131 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2878131 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26774608 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26774608 — Surrogate Endpoint (SUR): Serum creatinine
Study 20152247 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20152247 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11384090 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 3305118 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 21209232 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 21209232 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23043721 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 22156381 — Predictive Biomarker (PRD): Hormone receptor
Study 22156381 — Surrogate Endpoint (SUR): Bone mineral density
Study 29139142 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20620495 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 23853000 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 20079691 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20079691 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 15164106 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29444672 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27130844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 27130844 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27130844 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 27130844 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 27130844 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 20685303 — Surrogate Endpoint (SUR): Blood pressure
Study 14971151 — Surrogate Endpoint (SUR): Blood pressure
Study 22274319 — Surrogate Endpoint (SUR): Pathological complete response
Study 10472562 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 23887713 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 20886801 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11882622 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30504059 — Surrogate Endpoint (SUR): Blood pressure
Study 24393750 — Surrogate Endpoint (SUR): Blood pressure
Study 19351725 — Surrogate Endpoint (SUR): Serum calcium
Study 19351725 — Surrogate Endpoint (SUR): Blood pressure
Study 17584312 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8458362 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21212710 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 21212710 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15071277 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11789241 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 9110906 — Surrogate Endpoint (SUR): Blood pressure
Study 20943046 — Predictive Biomarker (PRD): CCRL2 mRNA
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 20943046 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14616416 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 14616416 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 14616416 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8157385 — Surrogate Endpoint (SUR): Blood pressure
Study 29274617 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29274617 — Predictive Biomarker (PRD): Hormone receptor
Study 28179349 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 11524040 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22867539 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 18809631 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10752988 — Surrogate Endpoint (SUR): Hematologic response
Study 8783785 — Surrogate Endpoint (SUR): Blood pressure
Study 8783785 — Surrogate Endpoint (SUR): Serum potassium
Study 1291700 — Surrogate Endpoint (SUR): Serum testosterone
Study 29558323 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29558323 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30061156 — Surrogate Endpoint (SUR): Blood pressure
Study 24806747 — Predictive Biomarker (PRD): DGAT2 mRNA
Genes: DGAT2; HMFN1045; UNQ738/PRO1433
Study 22907079 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22907079 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17704866 — Surrogate Endpoint (SUR): Blood pressure
Study 12768736 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1