TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26812052 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26812052 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 9780764 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 30253174 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 27448942 — Surrogate Endpoint (SUR): Blood pressure
Study 23347808 — Safety Biomarker (SAF): Reactive oxygen species
Study 12943960 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 10843747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29731416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16469079 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 16469079 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 15383514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16644639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16644639 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25053385 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 22031509 — Surrogate Endpoint (SUR): Blood pressure
Study 18819705 — Surrogate Endpoint (SUR): Blood pressure
Study 17180281 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 7933494 — Surrogate Endpoint (SUR): Serum sodium
Study 30630788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30630788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30630788 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28610669 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20876500 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20876500 — Predictive Biomarker (PRD): BCAR1 mRNA
Genes: BCAR1; CAS; CASS1; CRKAS
Study 31739991 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 7912163 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31706866 — Predictive Biomarker (PRD): HCG22 mRNA
Genes: HCG22; G2; PBMUCL2
Study 19957670 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 16148822 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 24285599 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24285599 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10471100 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30231173 — Safety Biomarker (SAF): Hyaluronic acid
Study 20693270 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 16466171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16466171 — Surrogate Endpoint (SUR): Blood pressure
Study 12825038 — Safety Biomarker (SAF): Hyaluronic acid
Study 9081681 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9081681 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23084677 — Safety Biomarker (SAF): Hyaluronic acid
Study 15860969 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12492610 — Surrogate Endpoint (SUR): Blood pressure
Study 9266226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25599738 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25599738 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 22234018 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11437176 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28304313 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 25887806 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 12165887 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 23883675 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17069905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17069905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11575286 — Surrogate Endpoint (SUR): Bone mineral density
Study 27501966 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27501966 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 25701774 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 11870809 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26046808 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26046808 — Surrogate Endpoint (SUR): Blood pressure
Study 21074333 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 8958495 — Surrogate Endpoint (SUR): Blood pressure
Study 3893128 — Surrogate Endpoint (SUR): Blood pressure
Study 7552586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30333315 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1531566 — Surrogate Endpoint (SUR): Blood pressure
Study 19462524 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 19462524 — Safety Biomarker (SAF): Interleukin 1
Study 12486868 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 2650798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27441461 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 1743242 — Surrogate Endpoint (SUR): Blood pressure
Study 31148988 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16434269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15262041 — Surrogate Endpoint (SUR): Blood pressure
Study 26147383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26147383 — Surrogate Endpoint (SUR): Blood pressure
Study 9688625 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 2909831 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 30594760 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 19453695 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18719788 — Surrogate Endpoint (SUR): Blood pressure
Study 11078311 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11078311 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11078311 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30420421 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30420421 — Surrogate Endpoint (SUR): Serum creatinine
Study 27593617 — Surrogate Endpoint (SUR): Blood pressure
Study 25014057 — Surrogate Endpoint (SUR): Blood pressure
Study 8137520 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2573377 — Surrogate Endpoint (SUR): Blood pressure
Study 28693427 — Surrogate Endpoint (SUR): Blood pressure
Study 17143189 — Surrogate Endpoint (SUR): Blood pressure
Study 15334195 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 2506754 — Surrogate Endpoint (SUR): Blood pressure
Study 11477855 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 11477855 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2672065 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31111697 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 22025856 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 17291931 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9152683 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27260515 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 22208477 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22208477 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 22208477 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8527074 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27417177 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26637849 — Predictive Biomarker (PRD): PAX2 mRNA
Genes: PAX2
Study 26637849 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 16601570 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 453892 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28376855 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28376855 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 28376855 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 16403097 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16403097 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 16403097 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 23635051 — Surrogate Endpoint (SUR): Blood pressure
Study 19521435 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 16183426 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 30768550 — Predictive Biomarker (PRD): AQP1 mRNA
Genes: AQP1; CHIP28
Study 27333960 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 2660333 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 31138063 — Surrogate Endpoint (SUR): Serum sodium
Study 21600843 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study 27749578 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 24886681 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 24886681 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24886681 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10447055 — Predictive Biomarker (PRD): SLC4A4 mRNA
Genes: SLC4A4; NBC; NBC1; NBCE1
Study 19183470 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 8687090 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17157900 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 508019 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 508019 — Surrogate Endpoint (SUR): Blood pressure
Study 28538371 — Surrogate Endpoint (SUR): Blood pressure
Study 19994687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 7894213 — Surrogate Endpoint (SUR): Blood pressure
Study 31927533 — Predictive Biomarker (PRD): PEX11A mRNA
Genes: PEX11A; PEX11
Study 31927533 — Predictive Biomarker (PRD): NLRP2 mRNA
Genes: NLRP2; NALP2; NBS1; PAN1; PYPAF2
Study 31927533 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31927533 — Predictive Biomarker (PRD): CTTN mRNA
Genes: CTTN; EMS1
Study 31927533 — Predictive Biomarker (PRD): D2HGDH mRNA
Genes: D2HGDH; D2HGD
Study 26677212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23728101 — Surrogate Endpoint (SUR): Blood pressure
Study 21126528 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9535210 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 23642377 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23642377 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15579791 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 15579791 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study 11254753 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9430375 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17962712 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9445199 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8037567 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28263039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24708857 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21983797 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 21983797 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 16123753 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 16123753 — Safety Biomarker (SAF): DRD2
Study 10368446 — Surrogate Endpoint (SUR): Blood pressure
Study 25322754 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15691618 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 15691618 — Surrogate Endpoint (SUR): Blood pressure
Study 27932570 — Surrogate Endpoint (SUR): Serum uric acid
Study 27932570 — Surrogate Endpoint (SUR): Blood pressure
Study 24204594 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24204594 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10902748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8883124 — Surrogate Endpoint (SUR): Bone mineral density
Study 8883124 — Surrogate Endpoint (SUR): Serum calcium
Study 1423336 — Surrogate Endpoint (SUR): Blood pressure
Study 24614628 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24614628 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24614628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15486802 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15486802 — Surrogate Endpoint (SUR): Blood pressure
Study 3731679 — Surrogate Endpoint (SUR): Blood pressure
Study 29778773 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27338467 — Surrogate Endpoint (SUR): Blood pressure
Study 21543653 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21543653 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 10503166 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23984312 — Surrogate Endpoint (SUR): Blood pressure
Study 23984312 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19424038 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 29335791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21436923 — Surrogate Endpoint (SUR): Blood pressure
Study 17126650 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9499812 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 1838916 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28213566 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28213566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21880799 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21880799 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18854202 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 24874285 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22230143 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21602259 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 21602259 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17462550 — Surrogate Endpoint (SUR): Serum calcium
Study 11562580 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 2683545 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30103216 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26283139 — Surrogate Endpoint (SUR): Blood pressure
Study 15561322 — Surrogate Endpoint (SUR): Blood pressure
Study 11731185 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20533221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31517677 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11899648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 11899648 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30854818 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study 18725429 — Surrogate Endpoint (SUR): Blood pressure
Study 12887479 — Surrogate Endpoint (SUR): Blood pressure
Study 30666969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23391635 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12794182 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12794182 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25349059 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19137426 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15832952 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 15832952 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24552317 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9475531 — Surrogate Endpoint (SUR): Blood pressure
Study 2225560 — Surrogate Endpoint (SUR): Blood pressure
Study 2225560 — Surrogate Endpoint (SUR): Serum creatinine
Study 24114461 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 24114461 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19426239 — Predictive Biomarker (PRD): OGT mRNA
Genes: OGT
Study 352706 — Surrogate Endpoint (SUR): Blood pressure
Study 11834534 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25922846 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 25922846 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25922846 — Surrogate Endpoint (SUR): Blood pressure
Study 24666922 — Surrogate Endpoint (SUR): Serum potassium
Study 15247958 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10805824 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 10805824 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2875927 — Surrogate Endpoint (SUR): Serum testosterone
Study 24896807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10221346 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10221346 — Surrogate Endpoint (SUR): Blood pressure
Study 7590642 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7590642 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2126985 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26911112 — Surrogate Endpoint (SUR): Blood pressure
Study 17294437 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 9236425 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9236425 — Surrogate Endpoint (SUR): Blood pressure
Study 15658647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15658647 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15658647 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31926484 — Surrogate Endpoint (SUR): Bone mineral density
Study 27125141 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 18464887 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 2179282 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2179282 — Surrogate Endpoint (SUR): Blood pressure
Study 27517842 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 16603964 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 29360622 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 29360622 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 10517211 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7670449 — Surrogate Endpoint (SUR): Plasma ammonia
Study 2175354 — Surrogate Endpoint (SUR): Blood pressure
Study 7030750 — Surrogate Endpoint (SUR): Blood pressure
Study 17414675 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16343099 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8949573 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8949573 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 8949573 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 24954556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7828347 — Surrogate Endpoint (SUR): Serum calcium
Study 26285023 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 24472321 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 10091762 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7584517 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7584517 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7584517 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 21550218 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15226463 — Surrogate Endpoint (SUR): Blood pressure
Study 29321031 — Surrogate Endpoint (SUR): Blood pressure
Study 29321031 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26978860 — Surrogate Endpoint (SUR): Serum creatinine
Study 17275225 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24377211 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 16144819 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 11007567 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7877825 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29038157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1