TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00790803 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02728882 — Predictive Biomarker (PRD): EPCAM mRNA
Genes: EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Study NCT02026986 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01799564 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT01799564 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03925454 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT04780490 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT00978835 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04430920 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00295919 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT03323034 — Predictive Biomarker (PRD): NEDD8 mRNA
Genes: NEDD8
Study NCT01302444 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT02301936 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04283669 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT03868059 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04563000 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06339255 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study NCT01923116 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04254744 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01712841 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00004351 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study NCT00416130 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT03113851 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00473421 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02407366 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02407366 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00409643 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04435925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04435925 — Safety Biomarker (SAF): Interleukin 1
Study NCT04435925 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04435925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04435925 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT02424396 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01998126 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01998126 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01998126 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00878098 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study NCT02435589 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00003125 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00003125 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00003125 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03376477 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01453478 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study NCT01453478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT03265821 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00253812 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT02049034 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT01409616 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT05287412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04283266 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT03143075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00944320 — Safety Biomarker (SAF): MTHFR
Study NCT00944320 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01642680 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02565914 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00352885 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01437696 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04094896 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03919136 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02039726 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01729156 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04147026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01572701 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT01572701 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03919981 — Predictive Biomarker (PRD): CTNS mRNA
Genes: CTNS
Study NCT04603664 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04603664 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT03970551 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00812994 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04357743 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01623102 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01623102 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00311740 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03611738 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03404817 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study NCT04342351 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01008696 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04914143 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04852263 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00005239 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04581967 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04581967 — Predictive Biomarker (PRD): ALDH3A1 mRNA
Genes: ALDH3A1; ALDH3
Study NCT03894852 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT02279823 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT00631189 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04873414 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03758521 — Safety Biomarker (SAF): Succinate-semialdehyde dehydrogenase
Genes: ALDH5A1; SSADH
Study NCT00588536 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04876534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01404819 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT04032769 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04347850 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02068365 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03210558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03210558 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00409253 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02594566 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03966261 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03966261 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03148912 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study NCT02077530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01717768 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00000487 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01881581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03946449 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT02736734 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT02092207 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT02404675 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01860339 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01788267 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02166307 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03270332 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03270332 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02012842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02012842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02012842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00173472 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT00173472 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study NCT00173472 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04495907 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03546270 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03664869 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT00251680 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00251680 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04473183 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03933579 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03258840 — Predictive Biomarker (PRD): PON2 mRNA
Genes: PON2
Study NCT03258840 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study NCT02898727 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02898727 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03701841 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01278043 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study NCT04231877 — Predictive Biomarker (PRD): CD79B mRNA
Genes: CD79B; B29; IGB
Study NCT00288067 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT04518800 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00593801 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study NCT01168739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01168739 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT04508439 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04508439 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03100786 — Predictive Biomarker (PRD): LTA4H mRNA
Genes: LTA4H; LTA4
Study NCT03632239 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00935415 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study NCT01472380 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT03039686 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03886519 — Predictive Biomarker (PRD): BRAP mRNA
Genes: BRAP; RNF52
Study NCT00902954 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01958502 — Predictive Biomarker (PRD): BMP2 mRNA
Genes: BMP2; BMP2A
Study NCT02330510 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02339324 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04335669 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04335669 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00626106 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00626106 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01568645 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01568645 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00837174 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT05285995 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03067688 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03067688 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03067688 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03734146 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00799721 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00799721 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT03144804 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00410293 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01118494 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study NCT01153802 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT01153802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT03765775 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00152698 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02562638 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02845401 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03874325 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02954523 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02954523 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT02954523 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00038051 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT02813837 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00754143 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03811639 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03811639 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study NCT03679156 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT03679156 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03679156 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03679156 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03431181 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01351012 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03182985 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00181584 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03954782 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02113241 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02113241 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04439071 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02603601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02603601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02603601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01285466 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00564304 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study NCT02599298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01835197 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT01418651 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00379015 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00129623 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04592913 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT01842386 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03589690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03589690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03589690 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03589690 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03840317 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04594785 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT04029350 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00682370 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT00167050 — Predictive Biomarker (PRD): SLK mRNA
Genes: SLK; KIAA0204; STK2
Study NCT03430024 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00458341 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02234323 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT00460057 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT03672422 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT03046186 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00271856 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02761746 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00622622 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00622622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00786396 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00006159 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01410578 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01410578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03367715 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00619905 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00219050 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01772004 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00042406 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00042406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02490436 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01522482 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT00576433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02636153 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT00489905 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02130804 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study NCT02130804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02130804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03706885 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT03706885 — Predictive Biomarker (PRD): CYP46A1 mRNA
Genes: CYP46A1; CYP46
Study NCT03706885 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT01051544 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02169180 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01187511 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT01187511 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04157569 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00940329 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02877212 — Predictive Biomarker (PRD): THPO mRNA
Genes: THPO; MGDF
Study NCT02877212 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT02686424 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02686424 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study NCT03876314 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02778646 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT02778646 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study NCT01337895 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03278262 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00782288 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00782288 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell