TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29150457 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 26225995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12441211 — Surrogate Endpoint (SUR): Blood pressure
Study 7723950 — Surrogate Endpoint (SUR): Blood pressure
Study 6779303 — Surrogate Endpoint (SUR): Blood pressure
Study 16914412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16914412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10930321 — Surrogate Endpoint (SUR): Blood pressure
Study 19213339 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 26579854 — Safety Biomarker (SAF): Interleukin 1
Study 19082693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19082693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19082693 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19082693 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19082693 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11975770 — Surrogate Endpoint (SUR): Blood pressure
Study 2894161 — Surrogate Endpoint (SUR): Blood pressure
Study 18294500 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 811427 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 811427 — Surrogate Endpoint (SUR): Blood pressure
Study 26323018 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 12592245 — Surrogate Endpoint (SUR): Bone mineral density
Study 6119103 — Surrogate Endpoint (SUR): Blood pressure
Study 26981576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26981576 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26981576 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22429436 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12373041 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9833600 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9833600 — Surrogate Endpoint (SUR): Blood pressure
Study 335687 — Surrogate Endpoint (SUR): Blood pressure
Study 26324372 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23490328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16428576 — Surrogate Endpoint (SUR): Blood pressure
Study 15213563 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30601429 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 30601429 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30408810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2480626 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1107462 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 25436213 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25436213 — Surrogate Endpoint (SUR): Serum sodium
Study 8781630 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29479010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29479010 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26965492 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25151031 — Surrogate Endpoint (SUR): Bone mineral density
Study 12148173 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17660602 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15876831 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8151107 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26672090 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 26672090 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22169113 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 22169113 — Predictive Biomarker (PRD): DMBX1 mRNA
Genes: DMBX1; MBX; OTX3; PAXB
Study 11783155 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 11783155 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 11783155 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7001242 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26393848 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26393848 — Surrogate Endpoint (SUR): Blood pressure
Study 2655452 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2655452 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31518058 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19646193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9773737 — Surrogate Endpoint (SUR): Blood pressure
Study 21568083 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 14999611 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12219065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12219065 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12219065 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25733651 — Surrogate Endpoint (SUR): Bone mineral density
Study 23985261 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10685792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10685792 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10685792 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10685792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23572413 — Surrogate Endpoint (SUR): Serum creatinine
Study 24399553 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 9010695 — Surrogate Endpoint (SUR): Blood pressure
Study 30977033 — Surrogate Endpoint (SUR): Serum creatinine
Study 11104737 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1735586 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1735586 — Surrogate Endpoint (SUR): Blood pressure
Study 28625242 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 23561971 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16636488 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2069791 — Surrogate Endpoint (SUR): Blood pressure
Study 20920276 — Surrogate Endpoint (SUR): Pathological complete response
Study 10499778 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 1758713 — Surrogate Endpoint (SUR): Blood pressure
Study 21305271 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21305271 — Surrogate Endpoint (SUR): Blood pressure
Study 19667239 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 15085385 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 15085385 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 15085385 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 11346128 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 31639060 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31639060 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29354994 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11099365 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2908820 — Surrogate Endpoint (SUR): Blood pressure
Study 12398236 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17010149 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17010149 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17010149 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10417864 — Surrogate Endpoint (SUR): Blood pressure
Study 25293351 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 22089249 — Surrogate Endpoint (SUR): Blood pressure
Study 20832062 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 17071935 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 7581970 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7581970 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 2372011 — Surrogate Endpoint (SUR): Blood pressure
Study 25893544 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25893544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25893544 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25893544 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16914379 — Surrogate Endpoint (SUR): Blood pressure
Study 28526223 — Surrogate Endpoint (SUR): Blood pressure
Study 18971533 — Surrogate Endpoint (SUR): Blood pressure
Study 8267146 — Surrogate Endpoint (SUR): Blood pressure
Study 3300834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30279267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23815535 — Surrogate Endpoint (SUR): Blood pressure
Study 18647232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18647232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18647232 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18647232 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 18647232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17050867 — Predictive Biomarker (PRD): CBX1 mRNA
Genes: CBX1; CBX
Study 8720537 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1448711 — Monitoring Biomarker (MOI): HBV DNA
Study 26313291 — Monitoring Biomarker (MOI): HBV DNA
Study 22189669 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11720758 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 6150724 — Surrogate Endpoint (SUR): Blood pressure
Study 29894608 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29894608 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27560704 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27560704 — Safety Biomarker (SAF): BDNF
Study 10673189 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 10673189 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 6662157 — Surrogate Endpoint (SUR): Blood pressure
Study 9028977 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1504638 — Surrogate Endpoint (SUR): Blood pressure
Study 22944289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17825690 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9922587 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9922587 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2156649 — Surrogate Endpoint (SUR): Serum calcium
Study 21624304 — Surrogate Endpoint (SUR): Serum creatinine
Study 30704266 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 2301751 — Surrogate Endpoint (SUR): Bacterial count
Study 26284338 — Predictive Biomarker (PRD): TLE3 mRNA
Genes: TLE3; KIAA1547
Study 11578885 — Surrogate Endpoint (SUR): Blood pressure
Study 30864188 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30864188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30864188 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30864188 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15915407 — Surrogate Endpoint (SUR): Blood pressure
Study 12777951 — Surrogate Endpoint (SUR): Blood pressure
Study 10490862 — Surrogate Endpoint (SUR): Blood pressure
Study 31116675 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 16585301 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16585301 — Surrogate Endpoint (SUR): Blood pressure
Study 10859628 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10859628 — Surrogate Endpoint (SUR): Blood pressure
Study 27535752 — Surrogate Endpoint (SUR): Bone mineral density
Study 26178502 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26178502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26178502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23795745 — Surrogate Endpoint (SUR): Serum creatinine
Study 27524882 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 15668500 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 25614446 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17578365 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17578365 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15477366 — Surrogate Endpoint (SUR): Serum testosterone
Study 12010353 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7872324 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 7872324 — Surrogate Endpoint (SUR): Serum calcium
Study 7872324 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 7872324 — Surrogate Endpoint (SUR): Bone mineral density
Study 24498872 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19694743 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19694743 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 19694743 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17171950 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17171950 — Surrogate Endpoint (SUR): Blood pressure
Study 24073583 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19004038 — Surrogate Endpoint (SUR): Bone mineral density
Study 15990257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28459238 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28459238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22822024 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22822024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1998761 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1998761 — Surrogate Endpoint (SUR): Blood pressure
Study 6689152 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 29559724 — Surrogate Endpoint (SUR): Blood pressure
Study 24381122 — Surrogate Endpoint (SUR): Serum creatinine
Study 24381122 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10210048 — Surrogate Endpoint (SUR): Blood pressure
Study 28028369 — Monitoring Biomarker (MOI): HBV DNA
Study 19930883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19930883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19930883 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15860850 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8390514 — Surrogate Endpoint (SUR): Blood pressure
Study 27137175 — Surrogate Endpoint (SUR): Blood pressure
Study 21203437 — Predictive Biomarker (PRD): TLR5 mRNA
Genes: TLR5; TIL3
Study 17083342 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15034215 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 26160208 — Predictive Biomarker (PRD): SLC6A14 mRNA
Genes: SLC6A14
Study 26160208 — Predictive Biomarker (PRD): HTR2C mRNA
Genes: HTR2C; HTR1C
Study 6750325 — Surrogate Endpoint (SUR): Serum sodium
Study 6750325 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6750325 — Surrogate Endpoint (SUR): Blood pressure
Study 9444927 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23957658 — Predictive Biomarker (PRD): FGF4 mRNA
Genes: FGF4; HST; HSTF1; KS3
Study 2686393 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28623892 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 26115976 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 26115976 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26115976 — Predictive Biomarker (PRD): Hormone receptor
Study 19727022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19727022 — Safety Biomarker (SAF): Interleukin 12
Study 11724457 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 26865200 — Surrogate Endpoint (SUR): Blood pressure
Study 21051293 — Surrogate Endpoint (SUR): Serum creatinine
Study 15740824 — Surrogate Endpoint (SUR): Blood pressure
Study 17484523 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28438539 — Predictive Biomarker (PRD): RARS1 mRNA
Genes: RARS1; RARS
Study 23474153 — Safety Biomarker (SAF): Interleukin 1
Study 17699214 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21834921 — Safety Biomarker (SAF): Human leucocyte antigen
Study 17413559 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 20027849 — Surrogate Endpoint (SUR): Bone mineral density
Study 20027849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15363817 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 15363817 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 29124630 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 2505717 — Surrogate Endpoint (SUR): Blood pressure
Study 2505717 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25223986 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12823779 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 12823779 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 23819814 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 21430255 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21430255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10747518 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8747844 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 8747844 — Surrogate Endpoint (SUR): Blood pressure
Study 8747844 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2478368 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 30308014 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 4013861 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27173467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22876725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19901104 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 11985485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28076331 — Predictive Biomarker (PRD): EPCAM mRNA
Genes: EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Study 12095313 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12095313 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7484890 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28028192 — Surrogate Endpoint (SUR): Blood pressure
Study 19682173 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 19682173 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 16321616 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16321616 — Surrogate Endpoint (SUR): Blood pressure
Study 9797755 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9797755 — Surrogate Endpoint (SUR): Blood pressure
Study 9797755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9797755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9797755 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29356445 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350