TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20542844 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20542844 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 29574445 — Surrogate Endpoint (SUR): Blood pressure
Study 29574445 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20541573 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15688279 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15688279 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11236255 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 11236255 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11236255 — Surrogate Endpoint (SUR): Blood pressure
Study 1318364 — Surrogate Endpoint (SUR): Serum creatinine
Study 17063001 — Surrogate Endpoint (SUR): Blood pressure
Study 1727903 — Surrogate Endpoint (SUR): Serum creatinine
Study 22851561 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 18077942 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2126437 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21880992 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15025782 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15025782 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26480969 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26480969 — Surrogate Endpoint (SUR): Blood pressure
Study 19297566 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17577323 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28049964 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23669294 — Surrogate Endpoint (SUR): Bone mineral density
Study 18505546 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 6746191 — Surrogate Endpoint (SUR): Blood pressure
Study 20586935 — Monitoring Biomarker (MOI): HBV DNA
Study 15817970 — Surrogate Endpoint (SUR): Blood pressure
Study 8026119 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17030231 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 12614193 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30591697 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 30591697 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30591697 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22052061 — Predictive Biomarker (PRD): ALDH1A2 mRNA
Genes: ALDH1A2; RALDH2
Study 19488642 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12081987 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14872173 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25697421 — Surrogate Endpoint (SUR): Serum creatinine
Study 10720212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10720212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6129979 — Surrogate Endpoint (SUR): Blood pressure
Study 25847374 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 22533725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22533725 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22533725 — Surrogate Endpoint (SUR): Blood pressure
Study 16361558 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 16361558 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31981043 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 30616014 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 22822092 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 22822092 — Surrogate Endpoint (SUR): Serum calcium
Study 22822092 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22822092 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22822092 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22822092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22822092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22822092 — Surrogate Endpoint (SUR): Blood pressure
Study 19178175 — Surrogate Endpoint (SUR): Serum sodium
Study 11714853 — Predictive Biomarker (PRD): ROPN1L mRNA
Genes: ROPN1L; ASP; RSPH11
Study 11714853 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 11714853 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29083275 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8844876 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22577748 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 18030450 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 8024729 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2509380 — Surrogate Endpoint (SUR): Blood pressure
Study 21923735 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 18852481 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 17591019 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10091411 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29321047 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 20499339 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study 11800042 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 11800042 — Safety Biomarker (SAF): BDNF
Study 31718402 — Predictive Biomarker (PRD): UBR5 mRNA
Genes: UBR5; EDD; EDD1; HYD; KIAA0896
Study 7892894 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19896041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16953150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21067346 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21067346 — Surrogate Endpoint (SUR): Blood pressure
Study 8707972 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24640990 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9150323 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2550696 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23965158 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ADAM11 mRNA
Genes: ADAM11; MDC
Study 23965158 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 23965158 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23965158 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 21831438 — Surrogate Endpoint (SUR): Blood pressure
Study 17146377 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29358464 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 20028850 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28103640 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 24098499 — Surrogate Endpoint (SUR): Blood pressure
Study 2100284 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2100284 — Surrogate Endpoint (SUR): Blood pressure
Study 31624837 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 21724580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21724580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19410250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19410250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22545895 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 19851098 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7106043 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21592974 — Surrogate Endpoint (SUR): Blood pressure
Study 11244190 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20105697 — Surrogate Endpoint (SUR): Blood pressure
Study 16129216 — Surrogate Endpoint (SUR): Serum creatinine
Study 12167391 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7585283 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31852444 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31852444 — Surrogate Endpoint (SUR): Blood pressure
Study 28698258 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23506627 — Surrogate Endpoint (SUR): Serum creatinine
Study 21946475 — Surrogate Endpoint (SUR): Blood pressure
Study 11849419 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 7484022 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 30203412 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11486851 — Surrogate Endpoint (SUR): Serum creatinine
Study 11486851 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26138864 — Surrogate Endpoint (SUR): Blood pressure
Study 10981559 — Surrogate Endpoint (SUR): Blood pressure
Study 20825523 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15764761 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14706505 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 16108864 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 16108864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26847983 — Surrogate Endpoint (SUR): Blood pressure
Study 15854087 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26242222 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 26242222 — Safety Biomarker (SAF): MTHFR
Study 24041978 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17623819 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2392131 — Surrogate Endpoint (SUR): Serum potassium
Study 23440491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17272770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12105256 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 7792377 — Surrogate Endpoint (SUR): Blood pressure
Study 2222942 — Surrogate Endpoint (SUR): Blood pressure
Study 2222942 — Surrogate Endpoint (SUR): Serum triglycerides
Study 693755 — Surrogate Endpoint (SUR): Blood pressure
Study 16051242 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12145066 — Surrogate Endpoint (SUR): Blood pressure
Study 7308277 — Surrogate Endpoint (SUR): Blood pressure
Study 16331821 — Surrogate Endpoint (SUR): Blood pressure
Study 12082493 — Surrogate Endpoint (SUR): Blood pressure
Study 12564607 — Safety Biomarker (SAF): DRD2
Study 6529680 — Surrogate Endpoint (SUR): Blood pressure
Study 28194841 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 16515981 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 3510393 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20651386 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18614918 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16212581 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 17397001 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15719490 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 30551223 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 22846147 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22846147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22846147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22846147 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19753648 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19753648 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29688121 — Predictive Biomarker (PRD): BCAR3 mRNA
Genes: BCAR3; NSP2; SH2D3B; UNQ271/PRO308
Study 16556409 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 11550107 — Surrogate Endpoint (SUR): Blood pressure
Study 6844664 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 29979618 — Predictive Biomarker (PRD): MUC22 mRNA
Genes: MUC22; G4; PBMUCL1
Study 29979618 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 25844686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25844686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25844686 — Surrogate Endpoint (SUR): Blood pressure
Study 23547239 — Surrogate Endpoint (SUR): Blood pressure
Study 20970976 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18713501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16540519 — Surrogate Endpoint (SUR): Bacterial count
Study 8726243 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 3034623 — Surrogate Endpoint (SUR): Blood pressure
Study 12685514 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 12685514 — Surrogate Endpoint (SUR): Blood pressure
Study 30640987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22505603 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 7751709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6363492 — Surrogate Endpoint (SUR): Serum potassium
Study 29223585 — Surrogate Endpoint (SUR): Blood pressure
Study 17286243 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 16119601 — Surrogate Endpoint (SUR): Blood pressure
Study 2179283 — Surrogate Endpoint (SUR): Blood pressure
Study 696981 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 696981 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 696981 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 696981 — Surrogate Endpoint (SUR): Blood pressure
Study 11354781 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27544678 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 26278513 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 20337606 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15044183 — Surrogate Endpoint (SUR): Blood pressure
Study 7996376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7996376 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25933201 — Safety Biomarker (SAF): Hyaluronic acid
Study 23959815 — Surrogate Endpoint (SUR): Blood pressure
Study 18362510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18362510 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 16172169 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16172169 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 30337444 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30337444 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 30337444 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28351412 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25938830 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 19804443 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8203183 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 31391092 — Surrogate Endpoint (SUR): Total kidney volume
Study 31391092 — Surrogate Endpoint (SUR): Serum creatinine
Study 28777672 — Surrogate Endpoint (SUR): Blood pressure
Study 21931327 — Surrogate Endpoint (SUR): Blood pressure
Study 24366918 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24366918 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16912957 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 16912957 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 8931749 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8931749 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 8931749 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 19195793 — Surrogate Endpoint (SUR): Blood pressure
Study 30394006 — Surrogate Endpoint (SUR): Blood pressure
Study 18715391 — Surrogate Endpoint (SUR): Blood pressure
Study 16542056 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16542056 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16542056 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16542056 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12850240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26508702 — Predictive Biomarker (PRD): MYOD1 mRNA
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 26508702 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 23650508 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8746285 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25118092 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21297126 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study 26963737 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 26963737 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 11996196 — Surrogate Endpoint (SUR): Blood pressure
Study 21680990 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24356886 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23614845 — Surrogate Endpoint (SUR): Blood pressure
Study 15855325 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 15855325 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15855325 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 12543751 — Predictive Biomarker (PRD): ROM1 mRNA
Genes: ROM1; TSPAN23
Study 22021897 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 19346511 — Surrogate Endpoint (SUR): Blood pressure
Study 11229224 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 332607 — Surrogate Endpoint (SUR): Serum calcium
Study 9491231 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29723928 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 16713661 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18782532 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23331339 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19476402 — Surrogate Endpoint (SUR): Bone mineral density
Study 8874977 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27521509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27521509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27521509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26168365 — Predictive Biomarker (PRD): MTSS1 mRNA
Genes: MTSS1; KIAA0429; MIM
Study 18463672 — Surrogate Endpoint (SUR): Blood pressure
Study 18463672 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12594698 — Surrogate Endpoint (SUR): Serum creatinine
Study 8221800 — Surrogate Endpoint (SUR): Blood pressure
Study 30229462 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12412824 — Surrogate Endpoint (SUR): Serum calcium
Study 8569136 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 25210141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23414448 — Surrogate Endpoint (SUR): Blood pressure
Study 21916906 — Safety Biomarker (SAF): Reactive oxygen species
Study 18355388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 17167137 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14566832 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 1350935 — Surrogate Endpoint (SUR): Blood pressure
Study 29794793 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 22382341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10752972 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25539986 — Safety Biomarker (SAF): Hyaluronic acid
Study 21330457 — Predictive Biomarker (PRD): SOX5 mRNA
Genes: SOX5
Study 11238495 — Surrogate Endpoint (SUR): Bone mineral density
Study 30688407 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26976446 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 20061337 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT