TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02885168 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03400982 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01633060 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01633060 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01633060 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT01633060 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01633060 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04044638 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03564093 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03143491 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT02352584 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study NCT02533791 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04685603 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03999125 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04604847 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04604847 — Safety Biomarker (SAF): BDNF
Study NCT02046135 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT01717846 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT00851110 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00003567 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT01083641 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01083641 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04170036 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04251065 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT00521963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01450137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02243566 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02608996 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04320303 — Predictive Biomarker (PRD): KLRC2 mRNA
Genes: KLRC2; NKG2C
Study NCT04034316 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01973738 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04653415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01575392 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02736760 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT00439465 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00439465 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study NCT00439465 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03504930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03828292 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04735900 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT01690832 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00182221 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00171054 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00818675 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01361451 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01868269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT01868269 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04024228 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00163137 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02853630 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03074942 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT00005796 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03158610 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01588405 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01588405 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02795910 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04273243 — Predictive Biomarker (PRD): CLN6 mRNA
Genes: CLN6
Study NCT02935543 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04015765 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT02372162 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT03485703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01470144 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04566536 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01843478 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03094702 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04211571 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT04541251 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01425866 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00304590 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT00898053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT03002493 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01057303 — Predictive Biomarker (PRD): MECOM mRNA
Genes: MECOM; EVI1; MDS1; PRDM3
Study NCT02248532 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00338936 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03527901 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study NCT05923112 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03101163 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03572634 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT01213810 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03312751 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02370706 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT02370706 — Surrogate Endpoint (SUR): Hematologic response
Study NCT04843085 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT00903916 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT00325533 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04635735 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02866487 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02241018 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00003820 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04174157 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT00494533 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03379571 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01772979 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01772979 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04330625 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04330625 — Predictive Biomarker (PRD): GCGR mRNA
Genes: GCGR
Study NCT00095290 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT06376305 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02336932 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT00025649 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study NCT01793207 — Predictive Biomarker (PRD): SFRP2 mRNA
Genes: SFRP2; FRP2; SARP1; FKSG12; UNQ361/PRO697
Study NCT00525135 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02413515 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02585804 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02585804 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03161418 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01050062 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05127382 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02666703 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study NCT04323189 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01418768 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT02429869 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00822042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00075894 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study NCT03780517 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT00576498 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study NCT04012411 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04012411 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04012411 — Safety Biomarker (SAF): BDNF
Study NCT03873519 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03833388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT00702312 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04786288 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03730454 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study NCT02272543 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02272543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00462527 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT00462527 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04390139 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04390139 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00442845 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01145391 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01373554 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT01565499 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01565499 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01363505 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04091867 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02759835 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01977144 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT02558023 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02958163 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT01801397 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01801397 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT02050932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04312997 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01417182 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01226563 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study NCT01554202 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT00564161 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00564161 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00133302 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT03425227 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00162877 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT02063971 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01601964 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01981876 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study NCT03587181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03587181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03587181 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study NCT00373659 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00309023 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT04118179 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study NCT01729117 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02091674 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02345278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT01082796 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04248257 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03513380 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02763579 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04586465 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01996215 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04136756 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT04419506 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03901183 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02924753 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00873860 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT04187079 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04187079 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT00899509 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00899509 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00899509 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT04486521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00956644 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03502629 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT03988114 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03988114 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03988114 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03988114 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01304784 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03924466 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02463513 — Safety Biomarker (SAF): MTHFR
Study NCT03486587 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05668572 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT05668572 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03002727 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT02973672 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03373786 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT00385333 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00385333 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT03042949 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01158950 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02277132 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT02746003 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03993743 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT00310778 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00310778 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00387595 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00387595 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00387595 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00387595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00509002 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00509002 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04327479 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT00312403 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study NCT00312403 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study NCT00312403 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT00312403 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study NCT00947011 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03370185 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03804034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04337385 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01907087 — Predictive Biomarker (PRD): Tripeptidyl-peptidase I
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study NCT02118350 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05103163 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00213811 — Predictive Biomarker (PRD): BBS1 mRNA
Genes: BBS1; BBS2L2
Study NCT00213811 — Predictive Biomarker (PRD): TTC8 mRNA
Genes: TTC8; BBS8
Study NCT02624128 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT04131478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04046263 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT04046263 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00095459 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT00095459 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00095459 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03000738 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study NCT01328171 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03943342 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04188925 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study NCT02886013 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study NCT04086875 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01473927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00609271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00609271 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03457233 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04344327 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03112590 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03112590 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02021968 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02457585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03509298 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT04663854 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02933593 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03624530 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03624530 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01698281 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01698281 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03060577 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03060577 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01460160 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01460160 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04082091 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00003881 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01639508 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01639508 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT01639508 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01639508 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT00847171 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF