TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27319812 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18243335 — Safety Biomarker (SAF): Interleukin 12
Study 16012274 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8653868 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24178631 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15955470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2265368 — Surrogate Endpoint (SUR): Blood pressure
Study 26306400 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26306400 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 26306400 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 9306168 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 8124120 — Surrogate Endpoint (SUR): Blood pressure
Study 29275373 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23006063 — Surrogate Endpoint (SUR): Serum sodium
Study 29611221 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19912315 — Surrogate Endpoint (SUR): Blood pressure
Study 17351280 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 16324168 — Surrogate Endpoint (SUR): Blood pressure
Study 2405804 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2405804 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30920620 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23360819 — Predictive Biomarker (PRD): LPIN1 mRNA
Genes: LPIN1; KIAA0188
Study 7921860 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 25204974 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 24634330 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 24634330 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 24634330 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 22582483 — Surrogate Endpoint (SUR): Blood pressure
Study 22582483 — Surrogate Endpoint (SUR): Serum sodium
Study 12134253 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31551228 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23897424 — Surrogate Endpoint (SUR): Blood pressure
Study 21768280 — Safety Biomarker (SAF): N-acetylneuraminic acid
Study 29435760 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 20856131 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20856131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3662543 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 3662543 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20952020 — Surrogate Endpoint (SUR): Blood pressure
Study 31663986 — Surrogate Endpoint (SUR): Blood pressure
Study 10584978 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30844804 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30844804 — Surrogate Endpoint (SUR): Blood pressure
Study 22525206 — Surrogate Endpoint (SUR): Blood pressure
Study 22525206 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22525206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20581787 — Surrogate Endpoint (SUR): Blood pressure
Study 20581787 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10487657 — Surrogate Endpoint (SUR): Bone mineral density
Study 26521100 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19874179 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 9028057 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1506125 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 23541513 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 27585605 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 27585605 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27585605 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 2979066 — Surrogate Endpoint (SUR): Blood pressure
Study 22856504 — Surrogate Endpoint (SUR): Blood pressure
Study 29112701 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23467946 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 12899584 — Surrogate Endpoint (SUR): Blood pressure
Study 29937301 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15055472 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 6611603 — Surrogate Endpoint (SUR): Blood pressure
Study 24225126 — Surrogate Endpoint (SUR): Blood pressure
Study 12544508 — Surrogate Endpoint (SUR): Blood pressure
Study 10481831 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 10481831 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10481831 — Surrogate Endpoint (SUR): Blood pressure
Study 8526782 — Surrogate Endpoint (SUR): Blood pressure
Study 31617025 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31617025 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21228335 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 3277912 — Surrogate Endpoint (SUR): Blood pressure
Study 21317163 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2149389 — Surrogate Endpoint (SUR): Blood pressure
Study 18721344 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18721344 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10475304 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6528619 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 6528619 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27359058 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16446681 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17895883 — Surrogate Endpoint (SUR): Blood pressure
Study 15996602 — Surrogate Endpoint (SUR): Blood pressure
Study 15482535 — Monitoring Biomarker (MOI): HBV DNA
Study 12133355 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7620696 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26267747 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 26267747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26267747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26267747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15051600 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18083355 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31176888 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 25042693 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 28304146 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24130358 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9041330 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30110007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27717299 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 18835931 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18835931 — Surrogate Endpoint (SUR): Blood pressure
Study 15043569 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15043569 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8142225 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 3144513 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 3144513 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 27197868 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25545856 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 18089770 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16513919 — Surrogate Endpoint (SUR): Blood pressure
Study 16513919 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11002872 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 11002872 — Surrogate Endpoint (SUR): Blood pressure
Study 9186076 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22482335 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17270528 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3980055 — Surrogate Endpoint (SUR): Blood pressure
Study 22048173 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10915072 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10915072 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18634152 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14637388 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1370236 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 30565017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28655596 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28655596 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7794572 — Surrogate Endpoint (SUR): Blood pressure
Study 18270817 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18270817 — Safety Biomarker (SAF): BDNF
Study 11817496 — Safety Biomarker (SAF): DRD2
Study 7554698 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 2202384 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2202384 — Surrogate Endpoint (SUR): Blood pressure
Study 22828124 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20980999 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20980999 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8635265 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 8635265 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26460907 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 1837202 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 30449623 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26861603 — Predictive Biomarker (PRD): Hormone receptor
Study 21922153 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 17439900 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 17439900 — Safety Biomarker (SAF): BDNF
Study 28864675 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21132308 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19438487 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 15465501 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11394516 — Surrogate Endpoint (SUR): Blood pressure
Study 7672871 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31477497 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26202150 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 16954164 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8316388 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 26554670 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 16921788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11120762 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 9212967 — Safety Biomarker (SAF): 51Cr-EDTA
Study 8427165 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 29754930 — Surrogate Endpoint (SUR): Blood pressure
Study 26410046 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 14728824 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 1875406 — Surrogate Endpoint (SUR): Blood pressure
Study 3485932 — Surrogate Endpoint (SUR): Serum creatinine
Study 29413495 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29413495 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 29413495 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18423747 — Surrogate Endpoint (SUR): Blood pressure
Study 11010055 — Surrogate Endpoint (SUR): Blood pressure
Study 11010055 — Surrogate Endpoint (SUR): Serum uric acid
Study 9059293 — Surrogate Endpoint (SUR): Serum creatinine
Study 27298017 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 23765950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9085297 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9085297 — Surrogate Endpoint (SUR): Blood pressure
Study 31301210 — Surrogate Endpoint (SUR): Blood pressure
Study 31301210 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29429138 — Predictive Biomarker (PRD): KCNQ1 mRNA
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study 29429138 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 29429138 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study 29429138 — Predictive Biomarker (PRD): NOS1AP mRNA
Genes: NOS1AP; CAPON; KIAA0464
Study 29429138 — Predictive Biomarker (PRD): NUBPL mRNA
Genes: NUBPL; C14orf127
Study 24513787 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23056520 — Safety Biomarker (SAF): Interleukin 1
Study 12784968 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 30649058 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30649058 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19101754 — Surrogate Endpoint (SUR): Bone mineral density
Study 15258682 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15258682 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18759644 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 31831255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31831255 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 31831255 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 31831255 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30870970 — Surrogate Endpoint (SUR): Blood pressure
Study 21996047 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 21996047 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21996047 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16414215 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16414215 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16414215 — Surrogate Endpoint (SUR): Blood pressure
Study 8808491 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15629215 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 15629215 — Predictive Biomarker (PRD): FMR1
Genes: FMRP; FRAXA; MGC87458
Study 12131220 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23340533 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 23340533 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 8270721 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 2826550 — Surrogate Endpoint (SUR): Blood pressure
Study 25403867 — Predictive Biomarker (PRD): CHIA mRNA
Genes: CHIA
Study 25403867 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 25403867 — Surrogate Endpoint (SUR): Blood pressure
Study 10860034 — Surrogate Endpoint (SUR): Probing pocket depth
Study 41229 — Surrogate Endpoint (SUR): Blood pressure
Study 28812321 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24002093 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24002093 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 24002093 — Surrogate Endpoint (SUR): Serum calcium
Study 19747876 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7803722 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29175149 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29175149 — Predictive Biomarker (PRD): Hormone receptor
Study 28526536 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12940872 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6205337 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 29659797 — Surrogate Endpoint (SUR): Serum creatinine
Study 23336612 — Predictive Biomarker (PRD): ARHGEF5 mRNA
Genes: ARHGEF5; TIM
Study 15643230 — Pharmacodynamic Biomarker (PDY): Bcl-2 to Bax
Study 1360665 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25560349 — Surrogate Endpoint (SUR): Blood pressure
Study 31959139 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27940700 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 15859929 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2534373 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26276354 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 26276354 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26276354 — Predictive Biomarker (PRD): Hormone receptor
Study 21720704 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 14524509 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 11109647 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9019177 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27865961 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27865961 — Predictive Biomarker (PRD): GRAP2 mRNA
Genes: GRAP2; GADS; GRB2L; GRID
Study 7620297 — Surrogate Endpoint (SUR): Blood pressure
Study 26168277 — Predictive Biomarker (PRD): BMAL1 mRNA
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 26168277 — Predictive Biomarker (PRD): CRY1 mRNA
Genes: CRY1; PHLL1
Study 26168277 — Predictive Biomarker (PRD): PER1 mRNA
Genes: PER1; KIAA0482; PER; RIGUI
Study 21736785 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 21736785 — Surrogate Endpoint (SUR): Blood pressure
Study 14623528 — Predictive Biomarker (PRD): Hormone receptor
Study 2859780 — Surrogate Endpoint (SUR): Blood pressure
Study 12851303 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12851303 — Predictive Biomarker (PRD): MC3R mRNA
Genes: MC3R
Study 29046405 — Surrogate Endpoint (SUR): Blood pressure
Study 26639851 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 23092731 — Safety Biomarker (SAF): Reactive oxygen species
Study 21823168 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21823168 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16202727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16202727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2968268 — Surrogate Endpoint (SUR): Blood pressure
Study 11755292 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 11720604 — Surrogate Endpoint (SUR): Blood pressure
Study 381957 — Surrogate Endpoint (SUR): Serum creatinine
Study 381957 — Surrogate Endpoint (SUR): Serum uric acid
Study 31544279 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 26177655 — Predictive Biomarker (PRD): CD200R1 mRNA
Genes: CD200R1; CD200R; CRTR2; MOX2R; OX2R; UNQ2522/PRO6015
Study 23920052 — Predictive Biomarker (PRD): TMEM176B mRNA
Genes: TMEM176B; LR8
Study 30305160 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 24844747 — Predictive Biomarker (PRD): SLC6A1 mRNA
Genes: SLC6A1; GABATR; GABT1; GAT1
Study 22825365 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 20116087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16181235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16181235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16181235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18801487 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9951916 — Monitoring Biomarker (MOI): HBV DNA
Study 2853753 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2853753 — Surrogate Endpoint (SUR): Blood pressure
Study 1841828 — Surrogate Endpoint (SUR): Blood pressure
Study 28142202 — Surrogate Endpoint (SUR): Serum creatinine
Study 20941459 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 20941459 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24557659 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 18936501 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 10100064 — Surrogate Endpoint (SUR): Blood pressure
Study 8889438 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 25376862 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 7570567 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 19118083 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 9336420 — Surrogate Endpoint (SUR): Serum creatinine
Study 3542323 — Surrogate Endpoint (SUR): Serum potassium
Study 25164220 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9374447 — Surrogate Endpoint (SUR): Serum creatinine
Study 27824811 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 21803547 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12566747 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9585793 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3