TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1745353 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 6979136 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26948070 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25523533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18753639 — Surrogate Endpoint (SUR): Blood pressure
Study 11092405 — Surrogate Endpoint (SUR): Bone mineral density
Study 8477914 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 3103338 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 25850030 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 25850030 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 1704534 — Surrogate Endpoint (SUR): Blood pressure
Study 20864251 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 9468364 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31937049 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31937049 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 21439850 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30623563 — Surrogate Endpoint (SUR): Blood pressure
Study 28700489 — Surrogate Endpoint (SUR): Serum creatinine
Study 16384561 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2981086 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29695765 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22361711 — Surrogate Endpoint (SUR): Blood pressure
Study 17971707 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17971707 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27288376 — Surrogate Endpoint (SUR): Blood pressure
Study 27288376 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26908742 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10335771 — Surrogate Endpoint (SUR): Blood pressure
Study 10335771 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28858362 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 28858362 — Surrogate Endpoint (SUR): Blood pressure
Study 25944073 — Surrogate Endpoint (SUR): Blood pressure
Study 22127508 — Surrogate Endpoint (SUR): Bone mineral density
Study 16391575 — Surrogate Endpoint (SUR): Serum calcium
Study 12633544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8518219 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3830118 — Surrogate Endpoint (SUR): Blood pressure
Study 27530188 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24460597 — Surrogate Endpoint (SUR): Blood pressure
Study 20636229 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10583037 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 1725620 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21412218 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 21412218 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 21412218 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 19643487 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 9177871 — Surrogate Endpoint (SUR): Serum calcium
Study 9177871 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 7954417 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29452815 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29452815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29452815 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20929123 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18512767 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 8704358 — Surrogate Endpoint (SUR): Bone mineral density
Study 2054405 — Surrogate Endpoint (SUR): Blood pressure
Study 22129890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22129890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17638699 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15868998 — Surrogate Endpoint (SUR): Blood pressure
Study 12774058 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12774058 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10563609 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 27111089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18661191 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 12562649 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26675765 — Predictive Biomarker (PRD): DMGDH mRNA
Genes: DMGDH
Study 26675765 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 9696231 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 7857733 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7857733 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31605198 — Surrogate Endpoint (SUR): Blood pressure
Study 24132976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24132976 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19675378 — Surrogate Endpoint (SUR): Blood pressure
Study 31277120 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22120032 — Predictive Biomarker (PRD): ZC3H12D mRNA
Genes: ZC3H12D; C6orf95; MCPIP4; TFL
Study 12383810 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 9578182 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2533074 — Surrogate Endpoint (SUR): Blood pressure
Study 15071126 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15071126 — Surrogate Endpoint (SUR): Serum calcium
Study 11297577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11297577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11297577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31518023 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 20153794 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1906745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1906745 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 1906745 — Safety Biomarker (SAF): Interleukin 1
Study 1906745 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25081694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9498433 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 26141208 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26141208 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23258572 — Surrogate Endpoint (SUR): Blood pressure
Study 22129852 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17442229 — Surrogate Endpoint (SUR): Blood pressure
Study 17442229 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15536162 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15536162 — Surrogate Endpoint (SUR): Blood pressure
Study 15522983 — Surrogate Endpoint (SUR): Blood pressure
Study 88708 — Surrogate Endpoint (SUR): Blood pressure
Study 31177099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27769783 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 27769783 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 19705518 — Surrogate Endpoint (SUR): Blood pressure
Study 19705518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11231744 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22278628 — Surrogate Endpoint (SUR): Blood pressure
Study 15625266 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 15894149 — Surrogate Endpoint (SUR): Bone mineral density
Study 24219348 — Surrogate Endpoint (SUR): Blood pressure
Study 9259871 — Surrogate Endpoint (SUR): Blood pressure
Study 29381791 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 20856164 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 788745 — Surrogate Endpoint (SUR): Blood pressure
Study 21559793 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21559793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16887123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16887123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15080372 — Surrogate Endpoint (SUR): Blood pressure
Study 15080372 — Surrogate Endpoint (SUR): Serum potassium
Study 2791759 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 31770207 — Surrogate Endpoint (SUR): Blood pressure
Study 15154945 — Surrogate Endpoint (SUR): Blood pressure
Study 11569481 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9259247 — Surrogate Endpoint (SUR): Bone mineral density
Study 10559704 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8742912 — Surrogate Endpoint (SUR): Blood pressure
Study 4056254 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29791287 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 29791287 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 27020037 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 25088835 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 27769289 — Surrogate Endpoint (SUR): Blood pressure
Study 15745385 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9469330 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9469330 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9469330 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31894022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31894022 — Surrogate Endpoint (SUR): Serum creatinine
Study 23670096 — Predictive Biomarker (PRD): NCOA3 mRNA
Genes: NCOA3; AIB1; BHLHE42; RAC3; TRAM1
Study 20800897 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 14742305 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 14742305 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 27423422 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 27423422 — Safety Biomarker (SAF): miR-205
Genes: MIR205
Study 27423422 — Safety Biomarker (SAF): miR-200a
Genes: MIR200A
Study 27423422 — Safety Biomarker (SAF): miR-133a
Study 27423422 — Predictive Biomarker (PRD): miR-135a
Study 26125735 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 15655382 — Surrogate Endpoint (SUR): Blood pressure
Study 15655382 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10069195 — Surrogate Endpoint (SUR): Serum creatinine
Study 21742103 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 21742103 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 30699178 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26355232 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26355232 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26355232 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 26355232 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 26355232 — Predictive Biomarker (PRD): PIK3R1 mRNA
Genes: PIK3R1; GRB1
Study 26355232 — Predictive Biomarker (PRD): VEGFB mRNA
Genes: VEGFB; VRF
Study 26355232 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26355232 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23002282 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 22099466 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17380850 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17380850 — Surrogate Endpoint (SUR): Blood pressure
Study 8480740 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 3613408 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31599994 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23430759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23430759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23430759 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30220262 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 11315126 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26364551 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26364551 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 1611329 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1611329 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30558079 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27138023 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 30419498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30419498 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19732457 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19732457 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 427822 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 1841788 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 6195483 — Surrogate Endpoint (SUR): Blood pressure
Study 25355252 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25355252 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 25355252 — Surrogate Endpoint (SUR): Serum creatinine
Study 20593353 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 18838662 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 18838662 — Predictive Biomarker (PRD): HMGXB3 mRNA
Genes: HMGXB3; KIAA0194; SMF
Study 11981083 — Surrogate Endpoint (SUR): Serum creatinine
Study 31086347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31086347 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27904156 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 27904156 — Surrogate Endpoint (SUR): Blood pressure
Study 24942223 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 22077236 — Surrogate Endpoint (SUR): Serum creatinine
Study 23298499 — Safety Biomarker (SAF): Hyaluronic acid
Study 12799209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2698569 — Surrogate Endpoint (SUR): Blood pressure
Study 327432 — Surrogate Endpoint (SUR): Blood pressure
Study 17014429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25440809 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 10576366 — Predictive Biomarker (PRD): BSN mRNA
Genes: BSN; KIAA0434; ZNF231
Study 10576366 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 26406150 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 26406150 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 26406150 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19787290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11092518 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9327316 — Surrogate Endpoint (SUR): Blood pressure
Study 29374796 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 29374796 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 27530775 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 20506391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9059137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24876451 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15804155 — Surrogate Endpoint (SUR): Blood pressure
Study 21712497 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 10899490 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3588662 — Surrogate Endpoint (SUR): Blood pressure
Study 18071341 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23068586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11810416 — Surrogate Endpoint (SUR): Bone mineral density
Study 9535437 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9535437 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 1827020 — Surrogate Endpoint (SUR): Blood pressure
Study 19455052 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16769582 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 16769582 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 15545790 — Surrogate Endpoint (SUR): Bone mineral density
Study 31432575 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 20106567 — Surrogate Endpoint (SUR): Blood pressure
Study 29228101 — Surrogate Endpoint (SUR): Blood pressure
Study 23762354 — Surrogate Endpoint (SUR): Bacterial count
Study 19115593 — Surrogate Endpoint (SUR): Blood pressure
Study 11211850 — Surrogate Endpoint (SUR): Blood pressure
Study 8776909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1385618 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 29960105 — Predictive Biomarker (PRD): PARN mRNA
Genes: PARN; DAN
Study 27583591 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18066136 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18066136 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17156477 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18783962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18783962 — Safety Biomarker (SAF): IL-6 and IL-10
Study 8247598 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23782588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23782588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8667057 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23097636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23097636 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23097636 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9683366 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27177865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27177865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27177865 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12679900 — Predictive Biomarker (PRD): ALPK1 mRNA
Genes: ALPK1; KIAA1527; LAK
Study 7562289 — Surrogate Endpoint (SUR): Bone mineral density
Study 2256469 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 2256469 — Surrogate Endpoint (SUR): Blood pressure
Study 31117810 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31117810 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27792836 — Surrogate Endpoint (SUR): Serum creatinine
Study 18854418 — Surrogate Endpoint (SUR): Serum creatinine
Study 9814488 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2612550 — Surrogate Endpoint (SUR): Blood pressure
Study 31526039 — Surrogate Endpoint (SUR): Blood pressure
Study 31526039 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19781326 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 19781326 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 11535983 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26669827 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209