TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21994233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21161650 — Surrogate Endpoint (SUR): Serum creatinine
Study 10534551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26488941 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26488941 — Surrogate Endpoint (SUR): Sperm parameters
Study 24500111 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23151451 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11668222 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 11668222 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27255750 — Surrogate Endpoint (SUR): Blood pressure
Study 19416298 — Monitoring Biomarker (MOI): Procalcitonin
Study 17554216 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12447868 — Monitoring Biomarker (MOI): HBV DNA
Study 10326847 — Surrogate Endpoint (SUR): Serum creatinine
Study 6351663 — Surrogate Endpoint (SUR): Blood pressure
Study 28081827 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 24075893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21839707 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 21839707 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 15005715 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 9579877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9579877 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2662037 — Surrogate Endpoint (SUR): Blood pressure
Study 31960275 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31960275 — Surrogate Endpoint (SUR): Serum testosterone
Study 15315114 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 15315114 — Surrogate Endpoint (SUR): Serum creatinine
Study 9706364 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 8586330 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 8586330 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31005973 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 31005973 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23435397 — Surrogate Endpoint (SUR): Blood pressure
Study 31961396 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19768295 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15807174 — Monitoring Biomarker (MOI): HBV DNA
Study 11232683 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15547161 — Surrogate Endpoint (SUR): Blood pressure
Study 28480692 — Predictive Biomarker (PRD): CRYL1 mRNA
Genes: CRYL1; CRY
Study 16493451 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7389253 — Surrogate Endpoint (SUR): Serum creatinine
Study 30883904 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27564775 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27564775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27564775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26974423 — Surrogate Endpoint (SUR): Blood pressure
Study 7840258 — Surrogate Endpoint (SUR): Blood pressure
Study 31190735 — Predictive Biomarker (PRD): IFNAR1 mRNA
Genes: IFNAR1; IFNAR
Study 17893310 — Surrogate Endpoint (SUR): Blood pressure
Study 8301105 — Surrogate Endpoint (SUR): Blood pressure
Study 26271057 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26271057 — Surrogate Endpoint (SUR): Blood pressure
Study 12936918 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12936918 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8441761 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8441761 — Surrogate Endpoint (SUR): Blood pressure
Study 24164308 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 24164308 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 24164308 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 29485323 — Surrogate Endpoint (SUR): Blood pressure
Study 26659069 — Surrogate Endpoint (SUR): Bone mineral density
Study 26659069 — Surrogate Endpoint (SUR): Serum calcium
Study 25283252 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22484523 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12446366 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 22135319 — Predictive Biomarker (PRD): LY86 mRNA
Genes: LY86; MD1
Study 19841931 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19841931 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12172327 — Surrogate Endpoint (SUR): Blood pressure
Study 10458542 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10458542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20930708 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20930708 — Surrogate Endpoint (SUR): Blood pressure
Study 11682388 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 7948468 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21142464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9386661 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24780069 — Predictive Biomarker (PRD): ZPR1 mRNA
Genes: ZPR1; ZNF259
Study 22375972 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 22402673 — Surrogate Endpoint (SUR): Bone mineral density
Study 17708612 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 14759393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14759393 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29069359 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15917338 — Surrogate Endpoint (SUR): Serum creatinine
Study 12891293 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12891293 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28799216 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 22542366 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 22542366 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 22542366 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22542366 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16739369 — Predictive Biomarker (PRD): SEPTIN3 mRNA
Genes: SEPTIN3; SEP3; SEPT3
Study 16739369 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 1354392 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1354392 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 1354392 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28528475 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28528475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28528475 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24946631 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 25815710 — Surrogate Endpoint (SUR): Blood pressure
Study 21852252 — Safety Biomarker (SAF): Hyaluronic acid
Study 15472792 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31916717 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 31215111 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31215111 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 27692128 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17666196 — Surrogate Endpoint (SUR): Blood pressure
Study 29626378 — Surrogate Endpoint (SUR): Blood pressure
Study 25218906 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 25218906 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 25218906 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25210473 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 22362063 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22362063 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 20622031 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12932605 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 12932605 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1910082 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20625319 — Surrogate Endpoint (SUR): Blood pressure
Study 12409741 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10374554 — Predictive Biomarker (PRD): USP9X mRNA
Genes: USP9X; DFFRX; FAM; USP9
Study 8195821 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21626050 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2841552 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 384738 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31308037 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18692175 — Surrogate Endpoint (SUR): Serum sodium
Study 24755139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24755139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22922813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22922813 — Surrogate Endpoint (SUR): Blood pressure
Study 10075387 — Surrogate Endpoint (SUR): Blood pressure
Study 2167800 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30679107 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10606847 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 1289508 — Surrogate Endpoint (SUR): Blood pressure
Study 18394499 — Surrogate Endpoint (SUR): Blood pressure
Study 12920631 — Surrogate Endpoint (SUR): Blood pressure
Study 12920631 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9224834 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 18206525 — Surrogate Endpoint (SUR): Blood pressure
Study 14532151 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 8673528 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29904126 — Surrogate Endpoint (SUR): Bone mineral density
Study 19357997 — Surrogate Endpoint (SUR): Blood pressure
Study 17453361 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2187945 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 10929741 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15882799 — Predictive Biomarker (PRD): GABRA5 mRNA
Genes: GABRA5
Study 8568534 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 28029329 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 28029329 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28029329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11981150 — Surrogate Endpoint (SUR): Blood pressure
Study 9787687 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26727655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24184245 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 22507330 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19850848 — Surrogate Endpoint (SUR): Blood pressure
Study 15612979 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 15612979 — Surrogate Endpoint (SUR): Blood pressure
Study 1968178 — Surrogate Endpoint (SUR): Blood pressure
Study 31162549 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 31162549 — Surrogate Endpoint (SUR): Blood pressure
Study 9284426 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3561160 — Surrogate Endpoint (SUR): Blood pressure
Study 18155056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18155056 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12789263 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 12789263 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 3653498 — Surrogate Endpoint (SUR): Blood pressure
Study 27687359 — Surrogate Endpoint (SUR): Blood pressure
Study 25558561 — Surrogate Endpoint (SUR): Blood pressure
Study 22811032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22811032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15868655 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15868655 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9585778 — Surrogate Endpoint (SUR): Serum creatinine
Study 29072432 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22136848 — Surrogate Endpoint (SUR): Bone mineral density
Study 22136848 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23434737 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 20350333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16624552 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 16624552 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 10962114 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1532316 — Surrogate Endpoint (SUR): Blood pressure
Study 23293333 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23293333 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23293333 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19567023 — Monitoring Biomarker (MOI): HBV DNA
Study 17878255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15268895 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 15268895 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15268895 — Surrogate Endpoint (SUR): Bone mineral density
Study 12402413 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 10682131 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29017162 — Surrogate Endpoint (SUR): Serum potassium
Study 24973862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19246729 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8492409 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 31818531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31818531 — Surrogate Endpoint (SUR): Blood pressure
Study 30326548 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 23657296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21290248 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 21290248 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 21290248 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 31937532 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 29739782 — Surrogate Endpoint (SUR): Blood pressure
Study 20200423 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 20200423 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 12032741 — Surrogate Endpoint (SUR): Blood pressure
Study 27858912 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 27858912 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25189855 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 22473652 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 3303439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3303439 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 26542509 — Surrogate Endpoint (SUR): Blood pressure
Study 21621331 — Surrogate Endpoint (SUR): Blood pressure
Study 16763334 — Monitoring Biomarker (MOI): HBV DNA
Study 29784592 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 22554354 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 10630736 — Surrogate Endpoint (SUR): Blood pressure
Study 29351748 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 24557758 — Surrogate Endpoint (SUR): Blood pressure
Study 22089379 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8741025 — Surrogate Endpoint (SUR): Blood pressure
Study 25330085 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16253600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16253600 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11876795 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 11876795 — Safety Biomarker (SAF): Hyaluronic acid
Study 7572740 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31416768 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 600190 — Surrogate Endpoint (SUR): Blood pressure
Study 23284039 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 18851852 — Surrogate Endpoint (SUR): Blood pressure
Study 16728220 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11724639 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11724639 — Surrogate Endpoint (SUR): Blood pressure
Study 9390536 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2658575 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 2658575 — Surrogate Endpoint (SUR): Blood pressure
Study 31482417 — Surrogate Endpoint (SUR): Serum creatinine
Study 1545669 — Surrogate Endpoint (SUR): Serum creatinine
Study 28464491 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 27504532 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27504532 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26084668 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 7527328 — Surrogate Endpoint (SUR): Blood pressure
Study 9097297 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9097297 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 3080695 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 25040898 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 19897255 — Surrogate Endpoint (SUR): Bone mineral density
Study 26540314 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26540314 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26540314 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22884381 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10206447 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8580383 — Safety Biomarker (SAF): Interleukin 1
Study 31749182 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 17243139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26581884 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 19933409 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11913598 — Surrogate Endpoint (SUR): Blood pressure
Study 10190422 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17974421 — Surrogate Endpoint (SUR): Serum calcium
Study 22112211 — Surrogate Endpoint (SUR): Blood pressure
Study 7474246 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25845393 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23868085 — Surrogate Endpoint (SUR): Blood pressure
Study 9397385 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3148789 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24345758 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 24345758 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15356550 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 15356550 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24395021 — Surrogate Endpoint (SUR): Blood pressure
Study 8108576 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31201036 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23166425 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 17503984 — Predictive Biomarker (PRD): TRIM32 mRNA
Genes: TRIM32; HT2A
Study 29738877 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 21246842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21246842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18411016 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26027245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9806026 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9806026 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27101815 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 24675714 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 19177819 — Surrogate Endpoint (SUR): Blood pressure
Study 10685331 — Surrogate Endpoint (SUR): Bone mineral density
Study 6740566 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309