TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15814544 — Surrogate Endpoint (SUR): Serum creatinine
Study 12351331 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12351331 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9527962 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 9527962 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9527962 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31837393 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 23835291 — Surrogate Endpoint (SUR): Bone mineral density
Study 16751820 — Surrogate Endpoint (SUR): Blood pressure
Study 22110219 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11530275 — Safety Biomarker (SAF): DRD2
Study 18450829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18450829 — Surrogate Endpoint (SUR): Serum creatinine
Study 16642224 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 16642224 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20172072 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12150618 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 10541947 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10541947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7599840 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 340492 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 31566307 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15494915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 29154277 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 11994339 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9920063 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31812227 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 31812227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9817605 — Surrogate Endpoint (SUR): Blood pressure
Study 8164053 — Surrogate Endpoint (SUR): Bone mineral density
Study 8164053 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30196031 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1334284 — Surrogate Endpoint (SUR): Blood pressure
Study 30595357 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 28971986 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 22450257 — Surrogate Endpoint (SUR): Serum testosterone
Study 21414045 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11485143 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8988911 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8988911 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2880903 — Surrogate Endpoint (SUR): Bacterial count
Study 22519907 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 22519907 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 16422854 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16422854 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 324723 — Surrogate Endpoint (SUR): Serum creatinine
Study 30998643 — Surrogate Endpoint (SUR): Bone mineral density
Study 23585192 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23680059 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 21646925 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16550731 — Surrogate Endpoint (SUR): Blood pressure
Study 8981304 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8981304 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8981304 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8981304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29690924 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 29690924 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26199465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14604715 — Predictive Biomarker (PRD): DLK1 mRNA
Genes: DLK1; DLK
Study 28275132 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 28275132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28275132 — Predictive Biomarker (PRD): INSR mRNA
Genes: INSR
Study 28275132 — Predictive Biomarker (PRD): NEGR1 mRNA
Genes: NEGR1; IGLON4; UNQ2433/PRO4993
Study 28275132 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 28275132 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 28275132 — Predictive Biomarker (PRD): FAT1 mRNA
Genes: FAT1; CDHF7; FAT
Study 28275132 — Safety Biomarker (SAF): Fatty acid binding protein 1
Genes: FABP1; FABPL
Study 28275132 — Predictive Biomarker (PRD): MC3R mRNA
Genes: MC3R
Study 25850750 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 23944767 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 17223112 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17223112 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17223112 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17223112 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17106926 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23609838 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17060064 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17060064 — Surrogate Endpoint (SUR): Blood pressure
Study 10936118 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28158932 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 26009829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26009829 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 26009829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26009829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21846551 — Predictive Biomarker (PRD): KCNN3 mRNA
Genes: KCNN3; K3
Study 19308727 — Surrogate Endpoint (SUR): Bone mineral density
Study 19308727 — Predictive Biomarker (PRD): Hormone receptor
Study 11520725 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 28416171 — Safety Biomarker (SAF): Hyaluronic acid
Study 27920516 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 20084314 — Surrogate Endpoint (SUR): Blood pressure
Study 20084314 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11461949 — Surrogate Endpoint (SUR): Serum creatinine
Study 28219329 — Surrogate Endpoint (SUR): Blood pressure
Study 9597213 — Surrogate Endpoint (SUR): Blood pressure
Study 29697274 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29697274 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22222177 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22222177 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26621361 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 26621361 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12181183 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 1936476 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19699071 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15738285 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 29103664 — Surrogate Endpoint (SUR): Blood pressure
Study 8025983 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30773266 — Surrogate Endpoint (SUR): Blood pressure
Study 25371534 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20714991 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 31187203 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 23460709 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15494637 — Surrogate Endpoint (SUR): Serum creatinine
Study 9741730 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3198299 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 26637922 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24431895 — Monitoring Biomarker (MOI): HBV DNA
Study 3585679 — Surrogate Endpoint (SUR): Blood pressure
Study 24739800 — Surrogate Endpoint (SUR): Blood pressure
Study 7841897 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 7841897 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31899823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31899823 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 31899823 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 28207497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3534201 — Surrogate Endpoint (SUR): Blood pressure
Study 31834099 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24866870 — Surrogate Endpoint (SUR): Blood pressure
Study 23139359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23139359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23139359 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20980412 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 1347763 — Surrogate Endpoint (SUR): Blood pressure
Study 3896701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 19920806 — Surrogate Endpoint (SUR): Blood pressure
Study 14583180 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14583180 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21114605 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17599426 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9802965 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9802965 — Surrogate Endpoint (SUR): Blood pressure
Study 9802965 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2681580 — Surrogate Endpoint (SUR): Blood pressure
Study 30742386 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 26279411 — Surrogate Endpoint (SUR): Blood pressure
Study 24912462 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 20212016 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 20212016 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 15811138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11759109 — Safety Biomarker (SAF): Hyaluronic acid
Study 31627728 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 23886531 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 23886531 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 23886531 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23886531 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 23886531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16755855 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11751733 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9431834 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16525946 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2151369 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11248153 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31870556 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 24095610 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24095610 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 24095610 — Predictive Biomarker (PRD): CA12 mRNA
Genes: CA12
Study 24095610 — Predictive Biomarker (PRD): PIGH mRNA
Genes: PIGH
Study 9745107 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9745107 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1979083 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31118371 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 31118371 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 17041001 — Surrogate Endpoint (SUR): Bone mineral density
Study 3309480 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21958773 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18559235 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18559235 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10971792 — Surrogate Endpoint (SUR): Blood pressure
Study 27430256 — Surrogate Endpoint (SUR): Serum testosterone
Study 16266472 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16266472 — Surrogate Endpoint (SUR): Blood pressure
Study 19539104 — Surrogate Endpoint (SUR): Blood pressure
Study 15193907 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15193907 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9989882 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9989882 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31567873 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31567873 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17717252 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 17990049 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 17990049 — Safety Biomarker (SAF): BDNF
Study 1752498 — Surrogate Endpoint (SUR): Blood pressure
Study 17698900 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17698900 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15449048 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 15449048 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21123443 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 6143736 — Surrogate Endpoint (SUR): Blood pressure
Study 30466891 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 29267994 — Surrogate Endpoint (SUR): Blood pressure
Study 7551920 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 28732826 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 24870575 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21696982 — Safety Biomarker (SAF): Fibroblast growth factor 1
Genes: FGF1
Study 19476405 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11075942 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24717684 — Predictive Biomarker (PRD): LCK mRNA
Genes: LCK
Study 15821888 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9512856 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9512856 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 9512856 — Surrogate Endpoint (SUR): Blood pressure
Study 23033348 — Surrogate Endpoint (SUR): Blood pressure
Study 10231333 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1857652 — Surrogate Endpoint (SUR): Blood pressure
Study 30194457 — Predictive Biomarker (PRD): BNC1 mRNA
Genes: BNC1; BNC
Study 30194457 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 22237690 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22237690 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16096751 — Surrogate Endpoint (SUR): Blood pressure
Study 25663312 — Surrogate Endpoint (SUR): Bone mineral density
Study 24396024 — Surrogate Endpoint (SUR): Blood pressure
Study 24396024 — Surrogate Endpoint (SUR): Serum potassium
Study 24396024 — Surrogate Endpoint (SUR): Serum uric acid
Study 31781758 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2890728 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 18235151 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15963401 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15963401 — Surrogate Endpoint (SUR): Blood pressure
Study 14673984 — Surrogate Endpoint (SUR): Serum creatinine
Study 8996671 — Surrogate Endpoint (SUR): Blood pressure
Study 29207479 — Surrogate Endpoint (SUR): Bone mineral density
Study 9372670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27281754 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 16927525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27806972 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20523295 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 12148100 — Surrogate Endpoint (SUR): Blood pressure
Study 9710006 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 9710006 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 7609864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2147029 — Surrogate Endpoint (SUR): Blood pressure
Study 26868507 — Safety Biomarker (SAF): Reactive oxygen species
Study 26868507 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15728647 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21835638 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10857963 — Surrogate Endpoint (SUR): Blood pressure
Study 3055922 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31719005 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28749549 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 22416896 — Surrogate Endpoint (SUR): Blood pressure
Study 11820954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31258526 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 31258526 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 31258526 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 31258526 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 26042362 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 23466396 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 11072779 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8468527 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 8468527 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8468527 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8468527 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17709109 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 17709109 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 12370562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12370562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10583448 — Surrogate Endpoint (SUR): Blood pressure
Study 1908493 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 17664199 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15548814 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 27091900 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27091900 — Surrogate Endpoint (SUR): Blood pressure
Study 25517733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10400054 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 6249137 — Surrogate Endpoint (SUR): Blood pressure
Study 12393770 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 30817193 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30817193 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 11755939 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7537797 — Predictive Biomarker (PRD): Hormone receptor
Study 22021080 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22021080 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 22021080 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 22021080 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 22021080 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17234505 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 17234505 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9718903 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3