TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01310686 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02285322 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001806 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00001806 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02180906 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study NCT03639545 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04235894 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03615404 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03536767 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT04806659 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT02452567 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT02452567 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01799005 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02612285 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT00065663 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study NCT01432223 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04447586 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03909074 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01581333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01010256 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT00307489 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04389554 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04224597 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00721617 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00721617 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03358875 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01558726 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT02346409 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT01900015 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT03660527 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01707563 — Predictive Biomarker (PRD): FBN1 mRNA
Genes: FBN1; FBN
Study NCT03914586 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT02467868 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT00483457 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00483457 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04265872 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04344509 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04669119 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01291745 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study NCT01863082 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00614900 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02169089 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02652455 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT03364556 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01485809 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01485809 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01650649 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00680654 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00889980 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT01681459 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02817360 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03611816 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study NCT01912599 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00465114 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00407485 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01074996 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT02282137 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01662804 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01625494 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02365402 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00425971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01036932 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04213469 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04213469 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04213469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT05079178 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01441596 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03159494 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03031353 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study NCT03473275 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03187704 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04382053 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00924833 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02804074 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01517282 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01554345 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03423992 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00368225 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study NCT04361240 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01163929 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00203866 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT03398954 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT00947895 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01584999 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03211611 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02160496 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02518802 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02518802 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00553813 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study NCT00048477 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT00048477 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00074932 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT00035256 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03258788 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01155674 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00674791 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01794234 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04462159 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03917589 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02263326 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01736488 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00268697 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00268697 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00599625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06092736 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study NCT01190436 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03619044 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT03619044 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03619044 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03029156 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00452647 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01634802 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02531061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01912521 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03019809 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00933608 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00579618 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00579618 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT01195194 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study NCT02132195 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT03145909 — Predictive Biomarker (PRD): PRLR mRNA
Genes: PRLR
Study NCT04407442 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT02907489 — Surrogate Endpoint (SUR): Bacterial count
Study NCT03293147 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00383994 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01528605 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03258034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03258034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00861354 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03410680 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00190177 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study NCT00190177 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study NCT01858909 — Predictive Biomarker (PRD): ITIH4 mRNA
Genes: ITIH4; IHRP; ITIHL1; PK120; PRO1851
Study NCT01858909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01858909 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01858909 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01858909 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03042572 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01695044 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01184755 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04408391 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02744105 — Predictive Biomarker (PRD): Liver iron
Study NCT02496663 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00321399 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT02287428 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT01923402 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03466775 — Safety Biomarker (SAF): Human leucocyte antigen
Study NCT04024436 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT00082667 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00082667 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03592771 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03284840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02705885 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04778891 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04326400 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01668498 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02990845 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02990845 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02990845 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02990845 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03248076 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03248076 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00422448 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT00422448 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study NCT02511106 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01049204 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT04523909 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03946345 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00171951 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT03855384 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00328120 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02449902 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02077114 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT00352417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00118937 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00118937 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04430400 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00042939 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00042939 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04217798 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT01180946 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04058847 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00623844 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03655704 — Predictive Biomarker (PRD): BRD4 mRNA
Genes: BRD4; HUNK1
Study NCT00661895 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02379975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03750890 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT03750890 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT03750890 — Predictive Biomarker (PRD): ATRX mRNA
Genes: ATRX; RAD54L; XH2
Study NCT03750890 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03750890 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03750890 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03707756 — Predictive Biomarker (PRD): COCH mRNA
Genes: COCH; COCH5B2; UNQ257/PRO294
Study NCT06439797 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study NCT03332173 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03975335 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01574820 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT05826613 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT05826613 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study NCT05826613 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04381052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01204905 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02233075 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02501616 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00268944 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT02288572 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02288572 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT00641069 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05060406 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01681394 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01779089 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01779089 — Surrogate Endpoint (SUR): Serum potassium
Study NCT00681226 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00136851 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00267865 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00389285 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study NCT04321096 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04321096 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04321096 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT04384705 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT02077556 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT02077556 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02077556 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT02277691 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03805685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03736889 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT03529838 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01672255 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03188887 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02004834 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00455104 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT01698567 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT03243838 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT04421534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00589745 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study NCT03515122 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05792982 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT00630981 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT02049684 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT04416100 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02837705 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study NCT00279591 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01301183 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04540952 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01768572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02693548 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT03578744 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01878955 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01003236 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01072058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01072058 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02188745 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05019014 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02092909 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study NCT04387149 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04387149 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01465789 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02326194 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01526850 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04527679 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT02823886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02823886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02823886 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT02823886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02823886 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT02823886 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT02823886 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study NCT02823886 — Safety Biomarker (SAF): Interleukin 1
Study NCT01028976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03317522 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00741923 — Surrogate Endpoint (SUR): Blood pressure