TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01316250 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01627587 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05266885 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01936896 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00005956 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05979142 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05979142 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00933777 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04402255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00089700 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03815318 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT02436720 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00553046 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02037555 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT03050229 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03661320 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT01538485 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT04056377 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02000141 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study NCT04508088 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03288142 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03145298 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03903315 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01822808 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04052178 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT00001272 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02323100 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02323100 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study NCT04711161 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study NCT02129907 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT02211677 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06201052 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02024516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02024516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00758706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01963481 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01963481 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01963481 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01783756 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00022087 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03754478 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00327002 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT03790605 — Safety Biomarker (SAF): Interleukin 1
Study NCT01370395 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT00402441 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03219970 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01258322 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01258322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01037777 — Predictive Biomarker (PRD): ATXN1 mRNA
Genes: ATXN1; ATX1; SCA1
Study NCT01037777 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study NCT01037777 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study NCT00022230 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00022230 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04455464 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01643928 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03976349 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT02471716 — Predictive Biomarker (PRD): CSF1 mRNA
Genes: CSF1
Study NCT02752893 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02752893 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01670305 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT01278940 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT01278940 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT03137264 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03137264 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02267993 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT02267993 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04295694 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03572036 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03572036 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT03572036 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01888614 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT01888614 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT03030976 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02249702 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT00997009 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00929448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00929448 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study NCT00929448 — Safety Biomarker (SAF): Interleukin 1
Study NCT00929448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00160472 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT05591313 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02730780 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT04973943 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04254770 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT02007226 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04050280 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00902603 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04480567 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00122551 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00157482 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01275209 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT03122431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03782857 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00573794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04035824 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01044186 — Predictive Biomarker (PRD): Liver iron
Study NCT04304638 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04304638 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00773539 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00773539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00773539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02120040 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT02780011 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT04173819 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01330004 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00664001 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01090323 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01090323 — Predictive Biomarker (PRD): Liver iron
Study NCT01324037 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01082549 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study NCT01082549 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT00344487 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03336255 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00561548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03867318 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00079690 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04683354 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT04683354 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT01161199 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01836003 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02081625 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04077957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03899181 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study NCT02194374 — Predictive Biomarker (PRD): RORA
Genes: RZRA; ROR1; ROR2; ROR3; NR1F1; ROR-alpha; RORalpha; RORa1
Study NCT02194374 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02111902 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT02111902 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02111902 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02377661 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03706248 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01715441 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04235296 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04235296 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04235296 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00860158 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01445873 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01445873 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04264871 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT01963221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01963221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02508818 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01510769 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02230917 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00924859 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03663205 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03663205 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04357223 — Predictive Biomarker (PRD): RTN4 mRNA
Genes: RTN4; KIAA0886; NOGO; My043; SP1507
Study NCT03980938 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT02750358 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01048268 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01113203 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05117866 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT01189019 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02862340 — Predictive Biomarker (PRD): FMR1
Genes: FMRP; FRAXA; MGC87458
Study NCT02862340 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study NCT00912184 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03545425 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT03545425 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT03204123 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00814957 — Safety Biomarker (SAF): DRD3
Study NCT03458923 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01112306 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01186913 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT00796471 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00796471 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00796471 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04048330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT05504161 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04102033 — Surrogate Endpoint (SUR): Platelet count response
Study NCT01453062 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study NCT01453062 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03537391 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03537391 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT02018497 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01159431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study NCT02467894 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02420769 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT00314561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00221143 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02776241 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT04575701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03317951 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study NCT04359901 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study NCT00756938 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02153138 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study NCT02153138 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00598299 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04060199 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03642145 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT06545448 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT04643054 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04643054 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04643054 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01262976 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00266253 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study NCT04126655 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT03374657 — Predictive Biomarker (PRD): RLBP1 mRNA
Genes: RLBP1; CRALBP
Study NCT06388486 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT03572205 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study NCT03572205 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study NCT00147069 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study NCT00147069 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study NCT00147069 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study NCT03263663 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02259634 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00681616 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04107727 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00157729 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00157729 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01960725 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00079911 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03474679 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00376272 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01250535 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study NCT01349049 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00433407 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01934569 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT04586985 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01222728 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT05008094 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT01282463 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01282463 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04188444 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT04381546 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT05409222 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05409222 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT00728221 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00626743 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT00626743 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00433862 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT00433862 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study NCT02015169 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00861159 — Predictive Biomarker (PRD): RALBP1 mRNA
Genes: RALBP1; RLIP; RLIP1; RLIP76
Study NCT00743808 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02977455 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02936531 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study NCT03903952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04884464 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01254994 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03847506 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03112083 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04118855 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03539549 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00575445 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03973333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT02073409 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT00257257 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02094144 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02240043 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03390504 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT03390504 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03775876 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05156541 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT06444893 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT06444893 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT06444893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study NCT06444893 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT06444893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06444893 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study NCT06444893 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06444893 — Safety Biomarker (SAF): MnSOD
Genes: SOD2; GClnc1; IPOB; GC1
Study NCT06444893 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01136005 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01469000 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03943121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01578031 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03887130 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01049009 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00077662 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT01455103 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A