TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19535188 — Surrogate Endpoint (SUR): Serum creatinine
Study 9549663 — Surrogate Endpoint (SUR): Blood pressure
Study 3072894 — Surrogate Endpoint (SUR): Blood pressure
Study 17356554 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17356554 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16950182 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16950182 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21332611 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 10846911 — Surrogate Endpoint (SUR): Blood pressure
Study 26772171 — Surrogate Endpoint (SUR): Blood pressure
Study 8293316 — Surrogate Endpoint (SUR): Blood pressure
Study 3191659 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18087660 — Surrogate Endpoint (SUR): Bone mineral density
Study 28681715 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 29035942 — Surrogate Endpoint (SUR): Blood pressure
Study 7995005 — Surrogate Endpoint (SUR): Blood pressure
Study 31714986 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31714986 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31714986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25906818 — Surrogate Endpoint (SUR): Blood pressure
Study 25906818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21457576 — Surrogate Endpoint (SUR): Bone mineral density
Study 16688994 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 12955333 — Surrogate Endpoint (SUR): Bone mineral density
Study 12955333 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8931841 — Surrogate Endpoint (SUR): Blood pressure
Study 22192151 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 22192151 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22192151 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18035202 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 1974509 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1974509 — Surrogate Endpoint (SUR): Blood pressure
Study 29070709 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 29070709 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 26332304 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19926054 — Surrogate Endpoint (SUR): Serum creatinine
Study 17143601 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 8058981 — Surrogate Endpoint (SUR): Blood pressure
Study 16280028 — Surrogate Endpoint (SUR): Blood pressure
Study 11987005 — Surrogate Endpoint (SUR): Bone mineral density
Study 31915152 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 17032876 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 11798687 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11798687 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11798687 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2086165 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19304472 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 19304472 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11967245 — Surrogate Endpoint (SUR): Blood pressure
Study 9527182 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28744857 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28744857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19736157 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 19736157 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 16802195 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21349928 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21349928 — Surrogate Endpoint (SUR): Serum potassium
Study 19660021 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11499564 — Surrogate Endpoint (SUR): Serum creatinine
Study 3365292 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17353577 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 17353577 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 17568241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17568241 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14597482 — Surrogate Endpoint (SUR): Blood pressure
Study 11824893 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 8335426 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23980348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23980348 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23980348 — Surrogate Endpoint (SUR): Blood pressure
Study 23980348 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23980348 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17045014 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17045014 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1287557 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 18256460 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 27427132 — Surrogate Endpoint (SUR): Blood pressure
Study 15764256 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15764256 — Surrogate Endpoint (SUR): Serum creatinine
Study 15764256 — Surrogate Endpoint (SUR): Serum uric acid
Study 2787289 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31239644 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 31239644 — Surrogate Endpoint (SUR): Blood pressure
Study 20031809 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22641256 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8778603 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 1405170 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 30595274 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 30595274 — Surrogate Endpoint (SUR): Blood pressure
Study 27618080 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27618080 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16082602 — Surrogate Endpoint (SUR): Blood pressure
Study 10456206 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 8642805 — Surrogate Endpoint (SUR): Blood pressure
Study 2144797 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2144797 — Surrogate Endpoint (SUR): Blood pressure
Study 7004678 — Surrogate Endpoint (SUR): Blood pressure
Study 7004678 — Surrogate Endpoint (SUR): Serum uric acid
Study 21047568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9587121 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7843867 — Surrogate Endpoint (SUR): Blood pressure
Study 2015476 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28449402 — Surrogate Endpoint (SUR): Blood pressure
Study 26030788 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 17898401 — Surrogate Endpoint (SUR): Blood pressure
Study 29718314 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29718314 — Predictive Biomarker (PRD): Hormone receptor
Study 29718314 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28296582 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15201943 — Safety Biomarker (SAF): Interleukin 1
Study 11535498 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 26729437 — Predictive Biomarker (PRD): Hormone receptor
Study 24814037 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15660119 — Surrogate Endpoint (SUR): Blood pressure
Study 11986206 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 8083913 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 8738112 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27286693 — Predictive Biomarker (PRD): GARS1 mRNA
Genes: GARS1; GARS
Study 31370809 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26325514 — Surrogate Endpoint (SUR): Blood pressure
Study 23722111 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 15749490 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 12131185 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12131185 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29384243 — Surrogate Endpoint (SUR): Blood pressure
Study 28986814 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28098515 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26125572 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 15027183 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9590187 — Surrogate Endpoint (SUR): Serum creatinine
Study 29636047 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27912986 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 17000226 — Surrogate Endpoint (SUR): Blood pressure
Study 8800590 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22285555 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15807810 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 25583157 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25583157 — Surrogate Endpoint (SUR): Blood pressure
Study 23941101 — Surrogate Endpoint (SUR): Blood pressure
Study 21142609 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 3945704 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25864194 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25864194 — Surrogate Endpoint (SUR): Blood pressure
Study 20090547 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18333870 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 11221289 — Surrogate Endpoint (SUR): Blood pressure
Study 24261301 — Surrogate Endpoint (SUR): Blood pressure
Study 14557430 — Surrogate Endpoint (SUR): Bone mineral density
Study 2987636 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2987636 — Surrogate Endpoint (SUR): Blood pressure
Study 1929022 — Surrogate Endpoint (SUR): Blood pressure
Study 6762195 — Predictive Biomarker (PRD): LUC7L3 mRNA
Genes: LUC7L3; CREAP1; CROP; O48
Study 27224744 — Surrogate Endpoint (SUR): Blood pressure
Study 20237044 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 15834273 — Surrogate Endpoint (SUR): Blood pressure
Study 12031981 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 7721409 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7721409 — Surrogate Endpoint (SUR): Blood pressure
Study 17525906 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21091365 — Surrogate Endpoint (SUR): Blood pressure
Study 15107600 — Surrogate Endpoint (SUR): Blood pressure
Study 26420678 — Surrogate Endpoint (SUR): Serum calcium
Study 26420678 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22471392 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11289497 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11289497 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 11289497 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25706772 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25706772 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23414791 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 23414791 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20026488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15681624 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10435208 — Surrogate Endpoint (SUR): Blood pressure
Study 26656357 — Surrogate Endpoint (SUR): Blood pressure
Study 19811373 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 2806927 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 27861239 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22475112 — Predictive Biomarker (PRD): EPHA1 mRNA
Genes: EPHA1; EPH; EPHT; EPHT1
Study 22475112 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17485709 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 15189916 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9826222 — Surrogate Endpoint (SUR): Blood pressure
Study 9826222 — Surrogate Endpoint (SUR): Serum creatinine
Study 29122953 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 29122953 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12603175 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 28088798 — Surrogate Endpoint (SUR): Blood pressure
Study 25794622 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14504951 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 10744590 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26923704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12529349 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8759815 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27317843 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 26244854 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15302007 — Surrogate Endpoint (SUR): Serum sodium
Study 3481038 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 26160254 — Surrogate Endpoint (SUR): Serum calcium
Study 11022182 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23688125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22507978 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22507978 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22507978 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 22507978 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 19835669 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19835669 — Safety Biomarker (SAF): BDNF
Study 17490962 — Surrogate Endpoint (SUR): Blood pressure
Study 15716684 — Surrogate Endpoint (SUR): Blood pressure
Study 12652153 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21173411 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29742699 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31125276 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21700602 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29759616 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21900646 — Surrogate Endpoint (SUR): Blood pressure
Study 21562746 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 29610401 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 14581438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17132270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7526028 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 31980691 — Surrogate Endpoint (SUR): Blood pressure
Study 27471125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 27471125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23319006 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 20929128 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 10871573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1327742 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1327742 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3893961 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 3893961 — Surrogate Endpoint (SUR): Blood pressure
Study 24809656 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23948023 — Surrogate Endpoint (SUR): Blood pressure
Study 21813065 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 21813065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21813065 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12777644 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9352450 — Surrogate Endpoint (SUR): Serum creatinine
Study 9352450 — Surrogate Endpoint (SUR): Blood pressure
Study 24104592 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24104592 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24104592 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9648994 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8122498 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 10950012 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28922590 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 19556043 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19556043 — Surrogate Endpoint (SUR): Serum creatinine
Study 28099429 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12030601 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12030601 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10406818 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10406818 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 20534755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20534755 — Safety Biomarker (SAF): Reactive oxygen species
Study 20534755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30934881 — Surrogate Endpoint (SUR): Bone mineral density
Study 9643668 — Surrogate Endpoint (SUR): Blood pressure
Study 18821888 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25946938 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 21325151 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 21325151 — Surrogate Endpoint (SUR): Blood pressure
Study 20031900 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20031900 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2698461 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28845908 — Surrogate Endpoint (SUR): Blood pressure
Study 25223731 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 11778187 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9234031 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8384948 — Surrogate Endpoint (SUR): Blood pressure
Study 30125761 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25022831 — Surrogate Endpoint (SUR): Blood pressure
Study 25022831 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15867204 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 29283929 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 29283929 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 25541015 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7024020 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 7024020 — Surrogate Endpoint (SUR): Blood pressure
Study 25726088 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14981104 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 14981104 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 21515017 — Surrogate Endpoint (SUR): Blood pressure
Study 12954742 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26022006 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22946768 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 22946768 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15339497 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9260011 — Surrogate Endpoint (SUR): Blood pressure
Study 8291866 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 29658455 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29658455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26333596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22380768 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 22380768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20113455 — Surrogate Endpoint (SUR): Blood pressure
Study 9181646 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31179618 — Surrogate Endpoint (SUR): Blood pressure
Study 28073411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28073411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28073411 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20308357 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 10351191 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS