TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27584910 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 19075260 — Surrogate Endpoint (SUR): Bone mineral density
Study 9413962 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9413962 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29635492 — Predictive Biomarker (PRD): RBM46 mRNA
Genes: RBM46
Study 29635492 — Predictive Biomarker (PRD): PEG3 mRNA
Genes: PEG3; KIAA0287; ZSCAN24
Study 29635492 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 29635492 — Predictive Biomarker (PRD): GRB10 mRNA
Genes: GRB10; GRBIR; KIAA0207
Study 29635492 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29635492 — Predictive Biomarker (PRD): GRIN3B mRNA
Genes: GRIN3B
Study 29635492 — Predictive Biomarker (PRD): OPCML mRNA
Genes: OPCML; IGLON1; OBCAM
Study 29635492 — Monitoring Biomarker (MOI): Apolipoprotein C-II
Genes: APOC2; APC2
Study 18729811 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12535810 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10232562 — Safety Biomarker (SAF): Glutamate dehydrogenase
Study 8553333 — Surrogate Endpoint (SUR): Blood pressure
Study 24372302 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22622108 — Surrogate Endpoint (SUR): Blood pressure
Study 29178891 — Predictive Biomarker (PRD): SHC1 mRNA
Genes: SHC1; SHC; SHCA
Study 3158243 — Surrogate Endpoint (SUR): Serum potassium
Study 22769423 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 9358963 — Surrogate Endpoint (SUR): Blood pressure
Study 7685452 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29764793 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 29764793 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 29764793 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 25867538 — Surrogate Endpoint (SUR): Bone mineral density
Study 1465288 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25022107 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 19884549 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19884549 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19884549 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 18326980 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18326980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8758853 — Surrogate Endpoint (SUR): Blood pressure
Study 28578639 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17201848 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 1890860 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31936767 — Surrogate Endpoint (SUR): Blood pressure
Study 24114668 — Safety Biomarker (SAF): Amphiregulin
Genes: AREG; AREGB; SDGF
Study 16938913 — Surrogate Endpoint (SUR): Blood pressure
Study 23318050 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18753745 — Surrogate Endpoint (SUR): Blood pressure
Study 17081355 — Surrogate Endpoint (SUR): Blood pressure
Study 14692654 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 14692654 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14692654 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29495655 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21311362 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15954914 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11602855 — Surrogate Endpoint (SUR): Serum creatinine
Study 22017520 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 20537751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26013003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26013003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26013003 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 26013003 — Safety Biomarker (SAF): Interleukin 1
Study 26013003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16969009 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14748820 — Surrogate Endpoint (SUR): Blood pressure
Study 24986773 — Surrogate Endpoint (SUR): Bone mineral density
Study 22621684 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22621684 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31754048 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 26175059 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 26175059 — Surrogate Endpoint (SUR): Bone mineral density
Study 22966789 — Surrogate Endpoint (SUR): Blood pressure
Study 15190802 — Predictive Biomarker (PRD): ZP3 mRNA
Genes: ZP3; ZP3A; ZP3B; ZPC
Study 11309009 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 31411975 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8915402 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8915402 — Surrogate Endpoint (SUR): Blood pressure
Study 24975596 — Predictive Biomarker (PRD): Hormone receptor
Study 18467543 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 10451911 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 15166654 — Surrogate Endpoint (SUR): Plasma testosterone level
Study 15166654 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9832603 — Surrogate Endpoint (SUR): Forced vital capacity
Study 396111 — Surrogate Endpoint (SUR): Blood pressure
Study 28112533 — Surrogate Endpoint (SUR): Blood pressure
Study 19925617 — Surrogate Endpoint (SUR): Blood pressure
Study 31096941 — Surrogate Endpoint (SUR): Blood pressure
Study 23398953 — Predictive Biomarker (PRD): FCGR2B
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study 23398953 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17142146 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17142146 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12663600 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10873879 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25901734 — Predictive Biomarker (PRD): ITGA2 mRNA
Genes: ITGA2; CD49B
Study 25901734 — Predictive Biomarker (PRD): F2R mRNA
Genes: F2R; CF2R; PAR1; TR
Study 25901734 — Predictive Biomarker (PRD): P2RY12 mRNA
Genes: P2RY12; HORK3
Study 24189254 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 16331754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23302662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6387210 — Surrogate Endpoint (SUR): Blood pressure
Study 30139835 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26333375 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 1424027 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22870185 — Surrogate Endpoint (SUR): Blood pressure
Study 7737713 — Surrogate Endpoint (SUR): Blood pressure
Study 6248010 — Surrogate Endpoint (SUR): Blood pressure
Study 24088993 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 21958068 — Surrogate Endpoint (SUR): Blood pressure
Study 8985103 — Surrogate Endpoint (SUR): Blood pressure
Study 1728157 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 25319597 — Predictive Biomarker (PRD): BCAR1 mRNA
Genes: BCAR1; CAS; CASS1; CRKAS
Study 23243245 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21308291 — Surrogate Endpoint (SUR): Probing pocket depth
Study 14564686 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11697754 — Surrogate Endpoint (SUR): Blood pressure
Study 16776681 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 27109816 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 22215473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7572689 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10848048 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10525558 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8675251 — Surrogate Endpoint (SUR): Blood pressure
Study 20021458 — Safety Biomarker (SAF): Reactive oxygen species
Study 12562110 — Surrogate Endpoint (SUR): Blood pressure
Study 786670 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 29308523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29308523 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29308523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29308523 — Safety Biomarker (SAF): Interleukin 1
Study 23668634 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 17766923 — Surrogate Endpoint (SUR): Blood pressure
Study 30372126 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 29699021 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 26873242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24444545 — Predictive Biomarker (PRD): EEF1A2 mRNA
Genes: EEF1A2; EEF1AL; STN
Study 17785618 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15932791 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9616263 — Surrogate Endpoint (SUR): Blood pressure
Study 30222051 — Predictive Biomarker (PRD): REG1A mRNA
Genes: REG1A; PSPS; PSPS1; REG
Study 20471706 — Surrogate Endpoint (SUR): Blood pressure
Study 19480865 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28532406 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28532406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27128001 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21146637 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 30586694 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30586694 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28765326 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 28765326 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 28765326 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 26621626 — Surrogate Endpoint (SUR): Blood pressure
Study 8553906 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7058754 — Surrogate Endpoint (SUR): Blood pressure
Study 11804663 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 7190495 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23547240 — Surrogate Endpoint (SUR): Blood pressure
Study 7967349 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26129694 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19819688 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24023786 — Predictive Biomarker (PRD): FNDC5 mRNA
Genes: FNDC5; FRCP2
Study 24023786 — Safety Biomarker (SAF): Reactive oxygen species
Study 19002384 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 19002384 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19002384 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11740820 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11740820 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11029398 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11029398 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 3543234 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 26042037 — Surrogate Endpoint (SUR): Blood pressure
Study 23816723 — Surrogate Endpoint (SUR): Blood pressure
Study 23816723 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23816723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23816723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22137686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22137686 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 24008122 — Surrogate Endpoint (SUR): Blood pressure
Study 20036363 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31738228 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 31738228 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 31738228 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31738228 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 31738228 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 28160545 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 28160545 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study 26162657 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 18405442 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18405442 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10101926 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 10101926 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 15957833 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 7669306 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2160490 — Surrogate Endpoint (SUR): Blood pressure
Study 433814 — Surrogate Endpoint (SUR): Serum calcium
Study 29961138 — Safety Biomarker (SAF): Hyaluronic acid
Study 29961138 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21646287 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21646287 — Predictive Biomarker (PRD): Liver iron
Study 11906445 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9477042 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28628003 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 18926439 — Surrogate Endpoint (SUR): Blood pressure
Study 16735174 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10466240 — Predictive Biomarker (PRD): TICAM2 mRNA
Genes: TICAM2; TIRAP3; TIRP; TRAM
Study 8626878 — Surrogate Endpoint (SUR): Blood pressure
Study 120078 — Surrogate Endpoint (SUR): Blood pressure
Study 11320586 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 11320586 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 8971305 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 2996310 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24991045 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7752177 — Surrogate Endpoint (SUR): Blood pressure
Study 31266489 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 31266489 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22193433 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22193433 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20645486 — Surrogate Endpoint (SUR): Blood pressure
Study 15978972 — Surrogate Endpoint (SUR): Serum testosterone
Study 30782714 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 23629739 — Surrogate Endpoint (SUR): Blood pressure
Study 1994867 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29886423 — Surrogate Endpoint (SUR): Blood pressure
Study 18766096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18766096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18766096 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 18766096 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18766096 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15974833 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 2064494 — Surrogate Endpoint (SUR): Blood pressure
Study 2064494 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18631958 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18631958 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15114097 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15114097 — Surrogate Endpoint (SUR): Serum creatinine
Study 11240440 — Surrogate Endpoint (SUR): Blood pressure
Study 3704568 — Surrogate Endpoint (SUR): Serum creatinine
Study 3704568 — Surrogate Endpoint (SUR): Blood pressure
Study 25420793 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 22396225 — Surrogate Endpoint (SUR): Blood pressure
Study 12190367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2121769 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2121769 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2121769 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 101223 — Surrogate Endpoint (SUR): Blood pressure
Study 24147895 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 24147895 — Surrogate Endpoint (SUR): Sperm parameters
Study 22209625 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 22209625 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 10770541 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10770541 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1900410 — Surrogate Endpoint (SUR): Serum calcium
Study 29851826 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 12183688 — Surrogate Endpoint (SUR): Blood pressure
Study 30077556 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30077556 — Surrogate Endpoint (SUR): Blood pressure
Study 22249781 — Surrogate Endpoint (SUR): Blood pressure
Study 15998892 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11982474 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17370488 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25796337 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18559985 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 15774609 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15774609 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2008547 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 31480676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28864705 — Surrogate Endpoint (SUR): Bone mineral density
Study 22803426 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22803426 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 22803426 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22803426 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21535135 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 15692263 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15692263 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10725066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10725066 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12643608 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16794492 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16794492 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 16794492 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 16794492 — Surrogate Endpoint (SUR): Blood pressure
Study 27601060 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 27601060 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 11900994 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9990816 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 2181859 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26399310 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 18404608 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12143088 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 23071122 — Surrogate Endpoint (SUR): Blood pressure
Study 31232898 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31232898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20729000 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15041604 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1