TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01775696 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study NCT01775696 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study NCT02120521 — Predictive Biomarker (PRD): MNDA mRNA
Genes: MNDA
Study NCT00864773 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00864773 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01997814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00681564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00681564 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT01720459 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02466113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT02466113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-20a
Genes: MIR20A
Study NCT02466113 — Predictive Biomarker (PRD): miR-106b
Genes: MIR106B
Study NCT02466113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-143
Genes: MIR143
Study NCT03313284 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02579746 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00769717 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04770376 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study NCT04770376 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02142166 — Predictive Biomarker (PRD): ACSM3 mRNA
Genes: ACSM3; SAH
Study NCT00152217 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT02690675 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study NCT02690675 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study NCT02690675 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT02690675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00407004 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study NCT00151034 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01184573 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT02251132 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01632891 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02555995 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04723199 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT01405638 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03706235 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00148603 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT00526058 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01746784 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01588782 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01339975 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study NCT01339975 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study NCT01225445 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01248026 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01091792 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01091792 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01091792 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01012206 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT00020462 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01889134 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00600769 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT03945812 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03945812 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT02489747 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02489747 — Safety Biomarker (SAF): BDNF
Study NCT01610791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03949829 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01958021 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01958021 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00482391 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01838577 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03859895 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study NCT03164798 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03164798 — Safety Biomarker (SAF): BDNF
Study NCT04078776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04078776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02833285 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study NCT02833285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02833285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02833285 — Predictive Biomarker (PRD): C-C motif chemokine 7
Genes: CCL7; MCP3; SCYA6; SCYA7
Study NCT03224871 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05709522 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT00895180 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01989351 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study NCT04596150 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04596150 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04596150 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04001569 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04001569 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT04001569 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04503057 — Predictive Biomarker (PRD): EBP mRNA
Genes: EBP
Study NCT06346444 — Predictive Biomarker (PRD): MECP2 mRNA
Genes: MECP2
Study NCT02102126 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00172198 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00172198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00172198 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00172198 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03904251 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT02041130 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02239250 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03762265 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00933920 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03452436 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01142817 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03615950 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00347152 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00865722 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT03366350 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02753686 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02753686 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02753686 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT00640640 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00640640 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00274599 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00620594 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03660696 — Predictive Biomarker (PRD): KCNQ1 mRNA
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study NCT02652975 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00384618 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02412592 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02144740 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00075335 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT00075335 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00075335 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT00432744 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT01948232 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01169584 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02273648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT00601913 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04163159 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04163159 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00748709 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00748709 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01669018 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05164939 — Predictive Biomarker (PRD): PELI1 mRNA
Genes: PELI1; PRISM
Study NCT02418988 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00686842 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03432416 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study NCT00494559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00321997 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00138983 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01367769 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT02376166 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT03216486 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04525612 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04220788 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002177 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01442064 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03738059 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03110445 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT03110445 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT01782651 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01782651 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00020670 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04603729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04307485 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study NCT01983657 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03492333 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT01820598 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01391065 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT02001896 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02001896 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03324425 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04665115 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01522404 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03734029 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02419989 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT00395486 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05430828 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02500069 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT02500069 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT00630071 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00630071 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT00630071 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02237846 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01568892 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT02974985 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00580424 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00580424 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00580424 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02303899 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT00408590 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00408590 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT03738943 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study NCT00721721 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03753100 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04701580 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01557400 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03209648 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01446731 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT00001812 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00418431 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT00305019 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04436471 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02149342 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study NCT02149342 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT01336686 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00913094 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00295581 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00751309 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT02501603 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02501603 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01841814 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00208377 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00308893 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00308893 — Safety Biomarker (SAF): BDNF
Study NCT01387204 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT01387204 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study NCT01891851 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01226719 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00340262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study NCT00340262 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT00340262 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00354107 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT01719393 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00906724 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT02900638 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03283969 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01357876 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT01302821 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT02457325 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03385239 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03200782 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03200782 — Safety Biomarker (SAF): Interleukin 1
Study NCT01885390 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01461486 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01236872 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04528615 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT02061397 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT02061397 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02061397 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05066646 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03556098 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03556098 — Predictive Biomarker (PRD): GIPR mRNA
Genes: GIPR
Study NCT01886248 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT04355858 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04355858 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01950429 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01950429 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03253432 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT03473925 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02434770 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03116542 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT03116542 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study NCT03116542 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT03116542 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study NCT01891344 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT02831270 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00054691 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00054691 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02696356 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study NCT02696356 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02696356 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT03466034 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01234220 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02827292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03564821 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT04132492 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04132492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04132492 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03051100 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01207687 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT04605757 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04640935 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04640935 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02653859 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00311012 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00901511 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03074266 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT02798991 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01092598 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01092598 — Safety Biomarker (SAF): BDNF
Study NCT03264131 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT05327283 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT05327283 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study NCT01289106 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00241098 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01002144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00697346 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT01158794 — Predictive Biomarker (PRD): Liver iron
Study NCT01996566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids