TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12356379 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23255849 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2698947 — Surrogate Endpoint (SUR): Blood pressure
Study 31796521 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 19454879 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 17444886 — Surrogate Endpoint (SUR): Blood pressure
Study 31264032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24218465 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 24218465 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 15636225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 7898595 — Surrogate Endpoint (SUR): Blood pressure
Study 28160190 — Surrogate Endpoint (SUR): Blood pressure
Study 22842478 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 22842478 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 22842478 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 22842478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 24444988 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23646099 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 23646099 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 18080043 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 16805716 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1627756 — Surrogate Endpoint (SUR): Blood pressure
Study 1627756 — Surrogate Endpoint (SUR): Serum potassium
Study 11579363 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30623490 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 27943397 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 24089534 — Safety Biomarker (SAF): Cardiac troponin T
Genes: TNNT2
Study 24089534 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7359503 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 8393606 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 3578925 — Predictive Biomarker (PRD): CDCA4 mRNA
Genes: CDCA4; HEPP
Study 27619403 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27619403 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23511706 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23511706 — Surrogate Endpoint (SUR): Blood pressure
Study 21508826 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21508826 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 15593207 — Surrogate Endpoint (SUR): Serum creatinine
Study 26225500 — Surrogate Endpoint (SUR): Blood pressure
Study 18706028 — Surrogate Endpoint (SUR): Blood pressure
Study 9682028 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 17377770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23048052 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 6841304 — Monitoring Biomarker (MOI): HBV DNA
Study 30058646 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30058646 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26177791 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 26177791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26177791 — Surrogate Endpoint (SUR): Bone mineral density
Study 20150883 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11788634 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7781864 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 1754636 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 27333382 — Monitoring Biomarker (MOI): HBV DNA
Study 17720098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17720098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17720098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7979533 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29061728 — Surrogate Endpoint (SUR): Blood pressure
Study 26867335 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26867335 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21931204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21931204 — Safety Biomarker (SAF): Interleukin 1
Study 18240965 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7032347 — Surrogate Endpoint (SUR): Blood pressure
Study 21318315 — Surrogate Endpoint (SUR): Blood pressure
Study 15368110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15368110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9519853 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2801555 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 822858 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29137842 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29137842 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 29137842 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 29137842 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29137842 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15637764 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15637764 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12394376 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12394376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12394376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31171755 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 15967849 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12581487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12581487 — Safety Biomarker (SAF): Interleukin 1
Study 9091475 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9091475 — Predictive Biomarker (PRD): DCN mRNA
Genes: DCN; SLRR1B
Study 7690364 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 30324422 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20529805 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 8706447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28168203 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 24034909 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 21357860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9883763 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2915293 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 2915293 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27039291 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15505001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7918139 — Surrogate Endpoint (SUR): Blood pressure
Study 29374674 — Surrogate Endpoint (SUR): Blood pressure
Study 29374674 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21645639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17046324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17046324 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17046324 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28222574 — Surrogate Endpoint (SUR): Blood pressure
Study 20423964 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16860169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12623974 — Surrogate Endpoint (SUR): Blood pressure
Study 31219517 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21884958 — Surrogate Endpoint (SUR): Blood pressure
Study 25265874 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 19356389 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20471234 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8915668 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27483064 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25197833 — Surrogate Endpoint (SUR): Blood pressure
Study 19604249 — Surrogate Endpoint (SUR): Blood pressure
Study 8261939 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3766413 — Surrogate Endpoint (SUR): Blood pressure
Study 25649018 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25649018 — Predictive Biomarker (PRD): KLK2 mRNA
Genes: KLK2
Study 25649018 — Predictive Biomarker (PRD): LGALS8 mRNA
Genes: LGALS8
Study 25649018 — Predictive Biomarker (PRD): LGALS3 mRNA
Genes: LGALS3; MAC2
Study 25649018 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24009294 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 24009294 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24009294 — Surrogate Endpoint (SUR): Blood pressure
Study 24009294 — Surrogate Endpoint (SUR): Serum creatinine
Study 24009294 — Surrogate Endpoint (SUR): Serum potassium
Study 14761120 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 22544016 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 9178345 — Surrogate Endpoint (SUR): Blood pressure
Study 25005017 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16610924 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 16610924 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30822621 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28946838 — Safety Biomarker (SAF): Hyaluronic acid
Study 2224165 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2224165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 445326 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31108227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24015915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12361204 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10516870 — Surrogate Endpoint (SUR): Blood pressure
Study 7711988 — Surrogate Endpoint (SUR): Blood pressure
Study 2791449 — Surrogate Endpoint (SUR): Blood pressure
Study 18565522 — Surrogate Endpoint (SUR): Blood pressure
Study 11377154 — Surrogate Endpoint (SUR): Blood pressure
Study 28486043 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 10904458 — Surrogate Endpoint (SUR): Blood pressure
Study 10904458 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18175062 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18175062 — Surrogate Endpoint (SUR): Blood pressure
Study 16455629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16455629 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1621888 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 19731013 — Predictive Biomarker (PRD): Hormone receptor
Study 7774139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23982478 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 11678967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9196416 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20188627 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 17970786 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 15997634 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15997634 — Surrogate Endpoint (SUR): Blood pressure
Study 6336977 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23364035 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9690571 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 30630742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30669181 — Surrogate Endpoint (SUR): Blood pressure
Study 19683590 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11939919 — Surrogate Endpoint (SUR): Blood pressure
Study 7626351 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7626351 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12147804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12147804 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10218753 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 402800 — Surrogate Endpoint (SUR): Blood pressure
Study 22396248 — Surrogate Endpoint (SUR): Blood pressure
Study 16731539 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 16731539 — Predictive Biomarker (PRD): Hormone receptor
Study 9037322 — Surrogate Endpoint (SUR): Blood pressure
Study 18487001 — Surrogate Endpoint (SUR): Blood pressure
Study 2687639 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2687639 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2687639 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27730425 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19634161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19634161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17526165 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 17526165 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 17526165 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 17526165 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30567490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23575360 — Surrogate Endpoint (SUR): Blood pressure
Study 9288279 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 3535002 — Surrogate Endpoint (SUR): Blood pressure
Study 15276504 — Surrogate Endpoint (SUR): Blood pressure
Study 31880993 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26732282 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24504222 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22425161 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 16230259 — Predictive Biomarker (PRD): SFPQ mRNA
Genes: SFPQ; PSF
Study 623136 — Surrogate Endpoint (SUR): Serum triglycerides
Study 623136 — Surrogate Endpoint (SUR): Serum uric acid
Study 623136 — Surrogate Endpoint (SUR): Blood pressure
Study 25842725 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20884007 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 20884007 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19349630 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 9682356 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31744119 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 31744119 — Safety Biomarker (SAF): BDNF
Study 26434651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26434651 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26434651 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17327378 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17327378 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 15642026 — Surrogate Endpoint (SUR): Probing pocket depth
Study 30507711 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30507711 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 30507711 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 30507711 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27806355 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 27806355 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27806355 — Surrogate Endpoint (SUR): Serum calcium
Study 25372006 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 8519720 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6763833 — Surrogate Endpoint (SUR): Blood pressure
Study 30248365 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21293156 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10479220 — Surrogate Endpoint (SUR): Blood pressure
Study 7741542 — Surrogate Endpoint (SUR): Serum calcium
Study 11850494 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 23911209 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 23911209 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19934619 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 18662417 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15673874 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 30178484 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20488759 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12585188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12585188 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26341920 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26341920 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 23731573 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23731573 — Surrogate Endpoint (SUR): Serum creatinine
Study 9697781 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26603917 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20857058 — Surrogate Endpoint (SUR): Blood pressure
Study 15459835 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15459835 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20628129 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 17587390 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17587390 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17587390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11895158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9861542 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 24232127 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20302678 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 1705432 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 8532025 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1676368 — Surrogate Endpoint (SUR): Blood pressure
Study 30154493 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26411813 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17574929 — Safety Biomarker (SAF): MTHFR
Study 9674467 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 9674467 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31412290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31412290 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 30111683 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9458419 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2466056 — Surrogate Endpoint (SUR): Blood pressure
Study 23631785 — Surrogate Endpoint (SUR): Blood pressure
Study 12894960 — Surrogate Endpoint (SUR): Blood pressure
Study 8864322 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8864322 — Surrogate Endpoint (SUR): Blood pressure
Study 1728909 — Surrogate Endpoint (SUR): Blood pressure
Study 22627104 — Surrogate Endpoint (SUR): Pathological complete response
Study 20825986 — Predictive Biomarker (PRD): COL3A1 mRNA
Genes: COL3A1
Study 11061616 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11061616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11061616 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8320947 — Surrogate Endpoint (SUR): Blood pressure