TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05361460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05361460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05361460 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03170375 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00090376 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study NCT00586794 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00586794 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00005421 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02032719 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02367963 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00098800 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT00537043 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00706147 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01505946 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00414648 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT00454935 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study NCT04213534 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT01569919 — Predictive Biomarker (PRD): TPBG mRNA
Genes: TPBG; 5T4
Study NCT05380869 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01453166 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03279718 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study NCT03279718 — Safety Biomarker (SAF): Interleukin 1
Study NCT03279718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03279718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03577899 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03577899 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00812955 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03066206 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03066206 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03066206 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03326648 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study NCT03326648 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study NCT03326648 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study NCT00735150 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT00735150 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04051255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04051255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03569189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03569189 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT01846754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04623658 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT00345761 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00345761 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00028340 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00028340 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03859076 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00647530 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01441388 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01441388 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01441388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT01441388 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01441388 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05437783 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT00099021 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT03824951 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04446286 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00219089 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04087356 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01533519 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT04207320 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04565509 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04576858 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00501644 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00823173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02803203 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03965845 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04710225 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03851237 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT00449215 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT02464956 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02464956 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT02536664 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02519699 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01982903 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study NCT00459758 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02805543 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02590952 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02938325 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03766607 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01849055 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02827617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02827617 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00158639 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03484611 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT03484611 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04358354 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00939354 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02598037 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study NCT03825133 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01342926 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03338985 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT03338985 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03338985 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT03478670 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT05617586 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT04436588 — Predictive Biomarker (PRD): DDX3X mRNA
Genes: DDX3X; DBX; DDX3
Study NCT03981042 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT00136058 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00307463 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02613871 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00767351 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT03217266 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT04122378 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01783444 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01783444 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03131206 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT03131206 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02441842 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00372957 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00587925 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04513782 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study NCT00143234 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03816189 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT04023916 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT00200200 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00200200 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00200200 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00200200 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02665325 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02221219 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study NCT03064932 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01418118 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00030147 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05233514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05233514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05233514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03071965 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study NCT01325064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01325064 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01507701 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05502458 — Predictive Biomarker (PRD): ELF3 mRNA
Genes: ELF3; ERT; ESX; JEN
Study NCT05502458 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00616642 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT03395028 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT04027647 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04027647 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04517318 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04517318 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00654537 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04427293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03130686 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00810680 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT03196830 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03196830 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03196830 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00956293 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00855465 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01082614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00120133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00120133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00120133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00120133 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03768427 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01440361 — Surrogate Endpoint (SUR): Platelet count response
Study NCT00956891 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04459819 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04535726 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01601184 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study NCT02737501 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03751397 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03751397 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT03751397 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT02234765 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01804452 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04227028 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03483662 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03126916 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00082810 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02525926 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01571622 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01571622 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03058965 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03247543 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study NCT00491517 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT00491517 — Predictive Biomarker (PRD): PKD2 mRNA
Genes: PKD2; TRPP2
Study NCT00491517 — Predictive Biomarker (PRD): PDK3 mRNA
Genes: PDK3; PDHK3
Study NCT00491517 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT04393246 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00481390 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study NCT02130349 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT02929485 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT00639002 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT00639002 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study NCT05153135 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05153135 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05153135 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04191486 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01245452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00886145 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00786162 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00212056 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT03980639 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03980639 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT03980639 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study NCT03980639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00498992 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00498992 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03376516 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT01161706 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01649180 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05017870 — Predictive Biomarker (PRD): KSR1 mRNA
Genes: KSR1; KSR
Study NCT02961270 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02054637 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT03419325 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03824080 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT01441934 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01441934 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01385150 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study NCT03201562 — Predictive Biomarker (PRD): PRX mRNA
Genes: PRX; KIAA1620
Study NCT04926571 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02799550 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00771836 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study NCT01923766 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04014426 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT03618381 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03618381 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01387750 — Predictive Biomarker (PRD): OGT mRNA
Genes: OGT
Study NCT02132403 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT00138645 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03302884 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01995747 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04786054 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study NCT00233532 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00233532 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00265915 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04123132 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02917005 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02917005 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04335071 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study NCT04335071 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01193101 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04928053 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study NCT02001623 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT02701205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02710188 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT05812326 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT02631148 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02631148 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03316287 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06246435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01465724 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02170324 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT01424332 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00900497 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04020718 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT01526629 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01070342 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02477670 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT01808495 — Predictive Biomarker (PRD): FBLN1 mRNA
Genes: FBLN1; PP213
Study NCT00588302 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03822650 — Predictive Biomarker (PRD): CLN5 mRNA
Genes: CLN5
Study NCT03761056 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06717763 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT01486550 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03898284 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04271410 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04591002 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04726995 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT02710539 — Surrogate Endpoint (SUR): Blood pressure