TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28667887 — Predictive Biomarker (PRD): TRO mRNA
Genes: TRO; KIAA1114; MAGED3
Study 28668356 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28669012 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28673924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28674140 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 28674838 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28674982 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 28676651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28676651 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28677510 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28679598 — Surrogate Endpoint (SUR): Blood pressure
Study 28679611 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28680917 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28680917 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28680960 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28681650 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 28681650 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 28681650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28683470 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28683470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 28683470 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28683470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28683470 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28683470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28683470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 28683745 — Predictive Biomarker (PRD): MAG mRNA
Genes: MAG; GMA
Study 28686124 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 28687077 — Predictive Biomarker (PRD): ITLN1 mRNA
Genes: ITLN1; INTL; ITLN; LFR; UNQ640/PRO1270
Study 28687625 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 28687627 — Surrogate Endpoint (SUR): Serum creatinine
Study 28693491 — Surrogate Endpoint (SUR): Blood pressure
Study 28693521 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 28694340 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28694840 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 28694840 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28698330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28698603 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 28698603 — Predictive Biomarker (PRD): CRISP2 mRNA
Genes: CRISP2; GAPDL5; TPX1
Study 28699641 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 28699641 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 28700272 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 28701316 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28701371 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 28701528 — Surrogate Endpoint (SUR): Blood pressure
Study 28701571 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 28701571 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28702218 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 28702218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28704280 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28704412 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 28705613 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 28705613 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 28705939 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28707983 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28707987 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28709774 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 28710215 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28710563 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 28710747 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28711173 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 28712102 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28712102 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28712102 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28712102 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28712102 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28713365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28713365 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28713365 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28713365 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 28713365 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 28713365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28713365 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28713365 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 28713365 — Predictive Biomarker (PRD): IL7 mRNA
Genes: IL7
Study 28713365 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28713581 — Predictive Biomarker (PRD): RPIA mRNA
Genes: RPIA; RPI
Study 28714866 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 28714866 — Predictive Biomarker (PRD): ITK mRNA
Genes: ITK; EMT; LYK
Study 28714866 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28714866 — Predictive Biomarker (PRD): CD200 mRNA
Genes: CD200; MOX1; MOX2; My033
Study 28714866 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study 28714868 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28716015 — Surrogate Endpoint (SUR): Blood pressure
Study 28716018 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 28716065 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28717512 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 28718100 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 28718760 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 28719225 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28719652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28720095 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 28720549 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 28721067 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28724445 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28724795 — Predictive Biomarker (PRD): FPR2 mRNA
Genes: FPR2; FPRH1; FPRL1; LXA4R
Study 28724795 — Predictive Biomarker (PRD): Phospholipase A2 inhibitory protein
Genes: ANXA1; ANX1; LPC1
Study 28725594 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28727542 — Predictive Biomarker (PRD): TSHR mRNA
Genes: TSHR; LGR3
Study 28727542 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28728751 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28728751 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28728751 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 28729326 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 28729911 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 28730692 — Surrogate Endpoint (SUR): Serum testosterone
Study 28732501 — Surrogate Endpoint (SUR): Blood pressure
Study 28735291 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28735759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28735759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28736819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28743198 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 28743683 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28747397 — Surrogate Endpoint (SUR): Blood pressure
Study 28750271 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28750271 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 28750642 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28751001 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28751001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28751088 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28751247 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28751247 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28751559 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 28752679 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28753747 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28755137 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28755389 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 28755782 — Surrogate Endpoint (SUR): Bone mineral density
Study 28757156 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 28757639 — Surrogate Endpoint (SUR): Blood pressure
Study 28759304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28759304 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28760541 — Surrogate Endpoint (SUR): Blood pressure
Study 28760669 — Predictive Biomarker (PRD): IGLL1 mRNA
Genes: IGLL1; IGL1
Study 28761384 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28761750 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28761750 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28764748 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28765146 — Predictive Biomarker (PRD): KCNMA1 mRNA
Genes: KCNMA1; KCNMA; SLO
Study 28765502 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28766094 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 28766459 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 28766535 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28768612 — Surrogate Endpoint (SUR): Blood pressure
Study 28768681 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 28769925 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28769925 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 28770094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28770408 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 28770408 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28771392 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 28771673 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 28772110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28776448 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 28776876 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 28777005 — Surrogate Endpoint (SUR): Serum creatinine
Study 28778448 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28778849 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 28779027 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28779027 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28780990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28780991 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28784598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28784670 — Predictive Biomarker (PRD): CCDC88A mRNA
Genes: CCDC88A; APE; GRDN; KIAA1212
Study 28787430 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28787430 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 28789693 — Surrogate Endpoint (SUR): Serum testosterone
Study 28791698 — Predictive Biomarker (PRD): POU2F1 mRNA
Genes: POU2F1; OCT1; OTF1
Study 28793098 — Surrogate Endpoint (SUR): Blood pressure
Study 28794136 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 28794257 — Predictive Biomarker (PRD): ZFYVE9 mRNA
Genes: ZFYVE9; MADHIP; SARA; SMADIP
Study 28794898 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28796812 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28796864 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28798090 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28800492 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28800628 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 28801442 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 28802168 — Monitoring Biomarker (MOI): HBV DNA
Study 28802255 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28802255 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 28802811 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28805662 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 28807118 — Safety Biomarker (SAF): Hyaluronic acid
Study 28807448 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 28808443 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28808443 — Surrogate Endpoint (SUR): Blood pressure
Study 28808480 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28810801 — Safety Biomarker (SAF): Reactive oxygen species
Study 28810837 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28810837 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28812172 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 28813164 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28815191 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 28815757 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study 28818208 — Predictive Biomarker (PRD): NR4A1 mRNA
Genes: NR4A1; GFRP1; HMR; NAK1
Study 28818208 — Predictive Biomarker (PRD): RYR2 mRNA
Genes: RYR2
Study 28818208 — Predictive Biomarker (PRD): PLN mRNA
Genes: PLN; PLB
Study 28818208 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 28820057 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28820321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): JPH2 mRNA
Genes: JPH2; JP2
Study 28822957 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 28822985 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 28823829 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28825151 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 28825151 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28825151 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ESR2 mRNA
Genes: ESR2; ESTRB; NR3A2
Study 28825603 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 28826066 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 28826699 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 28828532 — Surrogate Endpoint (SUR): Blood pressure
Study 28830573 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28830573 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28830912 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 28834623 — Monitoring Biomarker (MOI): HBV DNA
Study 28834795 — Surrogate Endpoint (SUR): Blood pressure
Study 28835849 — Surrogate Endpoint (SUR): Blood pressure
Study 28836957 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28836957 — Surrogate Endpoint (SUR): Blood pressure
Study 28837405 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28840039 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 28841389 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28841389 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28841389 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28841389 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 28841389 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 28841389 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 28841389 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28841495 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28841744 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 28844410 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 28844410 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28845238 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 28845238 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 28845508 — Surrogate Endpoint (SUR): Blood pressure
Study 28846559 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28846953 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 28847911 — Surrogate Endpoint (SUR): Blood pressure
Study 28847911 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28848672 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 28850430 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 28851109 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28851380 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 28851380 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 28851380 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 28851416 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 28851415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28851415 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28851423 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 28851447 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28851781 — Predictive Biomarker (PRD): SLC25A3 mRNA
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 28851978 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 28854543 — Surrogate Endpoint (SUR): Blood pressure
Study 28854726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28856009 — Surrogate Endpoint (SUR): Blood pressure
Study 28857778 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28857822 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28859185 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 28859325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28860342 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 28860342 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28861121 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28862877 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 28862877 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 28865109 — Surrogate Endpoint (SUR): Blood pressure
Study 28865109 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28866117 — Surrogate Endpoint (SUR): Serum creatinine
Study 28866726 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28866779 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 28867340 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF