TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18387656 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 18387656 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 7514842 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30472808 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26662809 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 20599002 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7887554 — Surrogate Endpoint (SUR): Serum creatinine
Study 2487803 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2487803 — Surrogate Endpoint (SUR): Blood pressure
Study 31996367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28067119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17692718 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18502301 — Surrogate Endpoint (SUR): Blood pressure
Study 9004108 — Surrogate Endpoint (SUR): Blood pressure
Study 3882307 — Surrogate Endpoint (SUR): Blood pressure
Study 31842921 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 24944242 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24944242 — Predictive Biomarker (PRD): AQP5 mRNA
Genes: AQP5
Study 24944242 — Predictive Biomarker (PRD): AVPR2 mRNA
Genes: AVPR2; ADHR; DIR; DIR3; V2R
Study 20711481 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15084928 — Surrogate Endpoint (SUR): Serum creatinine
Study 7524888 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29231295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29231295 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15677778 — Surrogate Endpoint (SUR): Blood pressure
Study 27138185 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27138185 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22713361 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 23048056 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 11263473 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 11263473 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 15188834 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 21113076 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 15106502 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8174201 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3344298 — Surrogate Endpoint (SUR): Blood pressure
Study 24991872 — Surrogate Endpoint (SUR): Blood pressure
Study 17904459 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 18201291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18201291 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8636283 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 8636283 — Surrogate Endpoint (SUR): Serum testosterone
Study 8636283 — Surrogate Endpoint (SUR): Bone mineral density
Study 1334713 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31655016 — Predictive Biomarker (PRD): ERFE mRNA
Genes: ERFE; C1QTNF15; CTRP15; FAM132B
Study 6421395 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23124692 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 6104743 — Surrogate Endpoint (SUR): Blood pressure
Study 17030764 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 575490 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 30799646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20658249 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9865559 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 26271327 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15623196 — Surrogate Endpoint (SUR): Blood pressure
Study 7965649 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24632963 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19593180 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31822016 — Surrogate Endpoint (SUR): Bone mineral density
Study 31822016 — Surrogate Endpoint (SUR): Blood pressure
Study 28433887 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15562367 — Surrogate Endpoint (SUR): Bone mineral density
Study 31912791 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 22089718 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22089718 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22089718 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10337502 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25690514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15641055 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 10550443 — Surrogate Endpoint (SUR): Bone mineral density
Study 29945500 — Predictive Biomarker (PRD): HDAC6 mRNA
Genes: HDAC6; KIAA0901; JM21
Study 1948092 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 6656240 — Surrogate Endpoint (SUR): Blood pressure
Study 5923 — Surrogate Endpoint (SUR): Blood pressure
Study 8602629 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25028506 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 25028506 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19695853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19695853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19695853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19695853 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 17378780 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 16278360 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29477138 — Surrogate Endpoint (SUR): Blood pressure
Study 27476110 — Predictive Biomarker (PRD): DCLRE1C mRNA
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study 22415569 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22415569 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22415569 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11820462 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 2289216 — Surrogate Endpoint (SUR): Blood pressure
Study 6988933 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6988933 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24135743 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 11743466 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 23902962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14651538 — Surrogate Endpoint (SUR): Serum creatinine
Study 8678624 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 8678624 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 1873206 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 6356902 — Surrogate Endpoint (SUR): Blood pressure
Study 29019319 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 19936896 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 19936896 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 15387489 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15387489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15387489 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 22024517 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22024517 — Surrogate Endpoint (SUR): Serum creatinine
Study 16306923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11068083 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28700102 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28700102 — Surrogate Endpoint (SUR): Blood pressure
Study 26027135 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7772078 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 729618 — Surrogate Endpoint (SUR): Blood pressure
Study 19727982 — Surrogate Endpoint (SUR): Serum calcium
Study 19727982 — Surrogate Endpoint (SUR): Bone mineral density
Study 11176084 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27881184 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27881184 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16314625 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 28262413 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19349312 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 11899785 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7968872 — Surrogate Endpoint (SUR): Blood pressure
Study 20595156 — Monitoring Biomarker (MOI): Procalcitonin
Study 18495508 — Surrogate Endpoint (SUR): Bone mineral density
Study 14687475 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 2116260 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2116260 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31638882 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 30711463 — Surrogate Endpoint (SUR): Blood pressure
Study 30711463 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28625255 — Monitoring Biomarker (MOI): Procalcitonin
Study 28625255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27352341 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27352341 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27352341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14714042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31443726 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30584113 — Surrogate Endpoint (SUR): Blood pressure
Study 21547878 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24896266 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 10424679 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 24352403 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9250554 — Surrogate Endpoint (SUR): Blood pressure
Study 31710340 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31710340 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 25240705 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25240705 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11873007 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21957161 — Surrogate Endpoint (SUR): Blood pressure
Study 8002338 — Surrogate Endpoint (SUR): Blood pressure
Study 29191819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25642687 — Surrogate Endpoint (SUR): Bone mineral density
Study 15132375 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 9040628 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30476916 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30476916 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 30476916 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27434036 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 18367385 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 12162502 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 23488277 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18940877 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18940877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18940877 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16489099 — Surrogate Endpoint (SUR): Blood pressure
Study 15055892 — Surrogate Endpoint (SUR): Blood pressure
Study 9335410 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9335410 — Surrogate Endpoint (SUR): Blood pressure
Study 26241865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24047486 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 15894410 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 10896698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 1345261 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1345261 — Surrogate Endpoint (SUR): Blood pressure
Study 29746386 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22035053 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 16514109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11136301 — Surrogate Endpoint (SUR): Blood pressure
Study 24528667 — Surrogate Endpoint (SUR): Blood pressure
Study 23324103 — Surrogate Endpoint (SUR): Blood pressure
Study 17385465 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 17385465 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15078738 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11317662 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7932162 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21150167 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 11118461 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7507638 — Surrogate Endpoint (SUR): Blood pressure
Study 21741344 — Predictive Biomarker (PRD): Liver iron
Study 19442346 — Surrogate Endpoint (SUR): Blood pressure
Study 15257094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7012398 — Surrogate Endpoint (SUR): Blood pressure
Study 21371993 — Surrogate Endpoint (SUR): Blood pressure
Study 23625188 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17112810 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9290464 — Surrogate Endpoint (SUR): Blood pressure
Study 8100627 — Surrogate Endpoint (SUR): Blood pressure
Study 19476474 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15045033 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 11472705 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11472705 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7831650 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26514759 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17447828 — Surrogate Endpoint (SUR): Blood pressure
Study 15044817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9701178 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28327450 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 14743040 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29037984 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 23515640 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21247520 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21247520 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8376687 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3519092 — Surrogate Endpoint (SUR): Blood pressure
Study 30477839 — Surrogate Endpoint (SUR): Blood pressure
Study 22801094 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10454438 — Surrogate Endpoint (SUR): Blood pressure
Study 30606886 — Predictive Biomarker (PRD): Hormone receptor
Study 28893875 — Surrogate Endpoint (SUR): Bone mineral density
Study 26172564 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23129746 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 16943110 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2766658 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27846092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27846092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27846092 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20702058 — Surrogate Endpoint (SUR): Blood pressure
Study 30151230 — Surrogate Endpoint (SUR): Blood pressure
Study 25667975 — Predictive Biomarker (PRD): CADM1 mRNA
Genes: CADM1; IGSF4; IGSF4A; NECL2; SYNCAM; TSLC1
Study 25667975 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 2916540 — Surrogate Endpoint (SUR): Blood pressure
Study 9577286 — Surrogate Endpoint (SUR): Blood pressure
Study 25463415 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19476983 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 17904983 — Surrogate Endpoint (SUR): Blood pressure
Study 11488797 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11488797 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30148987 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30148987 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22170716 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 22170716 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22170716 — Surrogate Endpoint (SUR): Bone mineral density
Study 28916992 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 25982649 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study 19646048 — Predictive Biomarker (PRD): NEB mRNA
Genes: NEB
Study 15735202 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21459902 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16875928 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16875928 — Surrogate Endpoint (SUR): Blood pressure
Study 11111968 — Surrogate Endpoint (SUR): Serum creatinine
Study 30744298 — Surrogate Endpoint (SUR): Blood pressure
Study 22230918 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22230918 — Surrogate Endpoint (SUR): Blood pressure
Study 15455745 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 31764462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31864178 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31659612 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 19367246 — Predictive Biomarker (PRD): BLOC1S2 mRNA
Genes: BLOC1S2; BLOS2; CEAP
Study 25910923 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22588852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19515371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19515371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19515371 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31882530 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 15649263 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15649263 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 15649263 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 12420198 — Surrogate Endpoint (SUR): Blood pressure
Study 12420198 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30462654 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 24662855 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 23860520 — Predictive Biomarker (PRD): Hormone receptor
Study 20962021 — Surrogate Endpoint (SUR): Blood pressure
Study 17309130 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 6948504 — Surrogate Endpoint (SUR): Blood pressure
Study 6948504 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30797542 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 25957330 — Surrogate Endpoint (SUR): Pathological complete response
Study 23621902 — Predictive Biomarker (PRD): BOC mRNA
Genes: BOC; UNQ604/PRO1190
Study 17968938 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1