TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21168818 — Predictive Biomarker (PRD): MYOC mRNA
Genes: MYOC; GLC1A; TIGR
Study 21173095 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21173499 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 21173653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21173653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21174506 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21176217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21176217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21176217 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21176218 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 21178824 — Surrogate Endpoint (SUR): Serum creatinine
Study 21178824 — Surrogate Endpoint (SUR): Blood pressure
Study 21179201 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21180274 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 21183651 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21183651 — Surrogate Endpoint (SUR): Blood pressure
Study 21183651 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21185022 — Surrogate Endpoint (SUR): Blood pressure
Study 21187495 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21193540 — Surrogate Endpoint (SUR): Blood pressure
Study 21193691 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21195036 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21195518 — Surrogate Endpoint (SUR): Serum creatinine
Study 21196729 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 21200021 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21200021 — Predictive Biomarker (PRD): SP8 mRNA
Genes: SP8
Study 21203546 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21206909 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 21208408 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21209029 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 21209029 — Predictive Biomarker (PRD): GNRHR mRNA
Genes: GNRHR; GRHR
Study 21209029 — Predictive Biomarker (PRD): ANOS1 mRNA
Genes: ANOS1; ADMLX; KAL; KAL1; KALIG1
Study 21209881 — Predictive Biomarker (PRD): PLEK mRNA
Genes: PLEK; P47
Study 21209881 — Predictive Biomarker (PRD): SLC22A16 mRNA
Genes: SLC22A16; OCT6
Study 21211990 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 21211990 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 21211990 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 21212386 — Predictive Biomarker (PRD): NCAM1 mRNA
Genes: NCAM1; NCAM
Study 21212770 — Surrogate Endpoint (SUR): Blood pressure
Study 21212770 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21216311 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21216880 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 21217080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21217520 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21219411 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21222188 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21224368 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21226927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21226927 — Surrogate Endpoint (SUR): Serum creatinine
Study 21232152 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 21232745 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 21233271 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 21233271 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 21242187 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 21242187 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 21242187 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 21242187 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 21242187 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 21245420 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 21245420 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21245726 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21245726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21245726 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21247312 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 21247312 — Predictive Biomarker (PRD): GNRHR mRNA
Genes: GNRHR; GRHR
Study 21247312 — Predictive Biomarker (PRD): ANOS1 mRNA
Genes: ANOS1; ADMLX; KAL; KAL1; KALIG1
Study 21247312 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 21249218 — Surrogate Endpoint (SUR): Blood pressure
Study 21252248 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21252248 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21252248 — Surrogate Endpoint (SUR): Blood pressure
Study 21252248 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21252248 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21252248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21256189 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21262916 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 21262916 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 21262992 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21263104 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21266211 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 21266211 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21267531 — Surrogate Endpoint (SUR): Pathological complete response
Study 21270271 — Surrogate Endpoint (SUR): Blood pressure
Study 21276128 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 21277098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21277098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21281486 — Predictive Biomarker (PRD): EPCAM mRNA
Genes: EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Study 21281873 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 21282185 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 21282484 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21287306 — Monitoring Biomarker (MOI): Procalcitonin
Study 21287306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21288612 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21288612 — Surrogate Endpoint (SUR): Blood pressure
Study 21296824 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21304982 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21308151 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 21310912 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21320355 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21321062 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21330601 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 21334404 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 21334595 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21334595 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21338429 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 21338429 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21343560 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 21343560 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 21343560 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 21343560 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 21343760 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21343760 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study 21343760 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21346617 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21349999 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21352561 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21355077 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study 21355077 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21355077 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 21355097 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21356079 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 21356079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21357403 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 21357403 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 21358414 — Surrogate Endpoint (SUR): Blood pressure
Study 21358414 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21359089 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 21359953 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21359953 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21360250 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21367924 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21367924 — Surrogate Endpoint (SUR): Serum sodium
Study 21367942 — Surrogate Endpoint (SUR): Serum potassium
Study 21368772 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 21368772 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 21371308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21371308 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 21372155 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 21372155 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 21372155 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 21372155 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 21372155 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 21372155 — Predictive Biomarker (PRD): BAALC mRNA
Genes: BAALC
Study 21372155 — Predictive Biomarker (PRD): MECOM mRNA
Genes: MECOM; EVI1; MDS1; PRDM3
Study 21372155 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 21372155 — Predictive Biomarker (PRD): MN1 mRNA
Genes: MN1
Study 21372155 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study 21372167 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21372302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21372302 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21372302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21372302 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21372613 — Surrogate Endpoint (SUR): Blood pressure
Study 21377994 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21381158 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21381892 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 21383241 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21383241 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 21383241 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 21383241 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 21383241 — Safety Biomarker (SAF): Th2 cell
Study 21383285 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 21383285 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 21383338 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21383338 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 21383338 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 21383338 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 21384515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21387287 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 21387287 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 21388310 — Surrogate Endpoint (SUR): Blood pressure
Study 21393027 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21393329 — Predictive Biomarker (PRD): Liver iron
Study 21396809 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21398330 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21398392 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21403127 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21403139 — Surrogate Endpoint (SUR): Blood pressure
Study 21406077 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21407181 — Safety Biomarker (SAF): let-7a
Study 21407181 — Predictive Biomarker (PRD): miR-145
Genes: MIR145
Study 21407181 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 21408154 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21410972 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 21414193 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 21414654 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 21414654 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 21414654 — Predictive Biomarker (PRD): AKT2 mRNA
Genes: AKT2
Study 21415776 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 21421838 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21421840 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 21421840 — Predictive Biomarker (PRD): SOX5 mRNA
Genes: SOX5
Study 21421840 — Predictive Biomarker (PRD): ITGAX mRNA
Genes: ITGAX; CD11C
Study 21421840 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 21422405 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21422474 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 21426510 — Surrogate Endpoint (SUR): Bone mineral density
Study 21426546 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 21426560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21429209 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21429209 — Surrogate Endpoint (SUR): Blood pressure
Study 21431345 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21436454 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 21436711 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 21436711 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21439671 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21441100 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 21443790 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 21444917 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21445332 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 21445332 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 21447719 — Safety Biomarker (SAF): Interleukin 12
Study 21447719 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 21448080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21448080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21448080 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 21448080 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21448080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21448080 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21450208 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 21450208 — Surrogate Endpoint (SUR): Blood pressure
Study 21450573 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21450900 — Surrogate Endpoint (SUR): Hematologic response
Study 21454794 — Safety Biomarker (SAF): Reactive oxygen species
Study 21454813 — Surrogate Endpoint (SUR): Blood pressure
Study 21457513 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21458303 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21459796 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21464053 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21464155 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 21465636 — Surrogate Endpoint (SUR): Hematologic response
Study 21467128 — Surrogate Endpoint (SUR): Blood pressure
Study 21467546 — Surrogate Endpoint (SUR): Hematologic response
Study 21468300 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21468309 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21471286 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21474353 — Predictive Biomarker (PRD): ASPA mRNA
Genes: ASPA; ACY2; ASP
Study 21474786 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 21475692 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21475692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21477202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21477202 — Predictive Biomarker (PRD): VCAM1 mRNA
Genes: VCAM1
Study 21477202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21478218 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21478218 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 21478667 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 21478667 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21480191 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21480819 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21481640 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21481713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21481713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21481713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21482186 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21487108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21487108 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21487288 — Surrogate Endpoint (SUR): Pathological complete response
Study 21489579 — Surrogate Endpoint (SUR): Blood pressure
Study 21489874 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 21492428 — Surrogate Endpoint (SUR): Bone mineral density
Study 21493699 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 21493737 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21493817 — Predictive Biomarker (PRD): KIF6 mRNA
Genes: KIF6; C6orf102
Study 21493817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21493817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21494336 — Predictive Biomarker (PRD): PNN mRNA
Genes: PNN; DRS; MEMA
Study 21494337 — Predictive Biomarker (PRD): SCAMP1 mRNA
Genes: SCAMP1; SCAMP
Study 21497495 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 21497773 — Predictive Biomarker (PRD): SLC22A5 mRNA
Genes: SLC22A5; OCTN2
Study 21497773 — Predictive Biomarker (PRD): SLCO4C1 mRNA
Genes: SLCO4C1; OATP4C1; OATPX; SLC21A20