TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17174201 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 3306639 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27596284 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 27596284 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 15813818 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 12014211 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16290983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16290983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16290983 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12017502 — Surrogate Endpoint (SUR): Blood pressure
Study 10223230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 10223230 — Predictive Biomarker (PRD): Microsatellite instability
Study 2550647 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2550647 — Surrogate Endpoint (SUR): Serum creatinine
Study 29451036 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 18433755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10825311 — Surrogate Endpoint (SUR): Blood pressure
Study 8851608 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27410490 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 11910671 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7079142 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23866694 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19821718 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16423088 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 10633220 — Surrogate Endpoint (SUR): Bone mineral density
Study 8866880 — Surrogate Endpoint (SUR): Blood pressure
Study 6661468 — Surrogate Endpoint (SUR): Blood pressure
Study 25188543 — Predictive Biomarker (PRD): ADCYAP1R1 mRNA
Genes: ADCYAP1R1
Study 25188543 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 25188543 — Predictive Biomarker (PRD): CRHR1 mRNA
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 25188543 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 25188543 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 25188543 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 25188543 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 25188543 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 25188543 — Predictive Biomarker (PRD): NTRK2 mRNA
Genes: NTRK2; TRKB
Study 25188543 — Predictive Biomarker (PRD): PCLO mRNA
Genes: PCLO; ACZ; KIAA0559
Study 20969660 — Safety Biomarker (SAF): Hyaluronic acid
Study 9665673 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9665673 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27048345 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 9292587 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10773503 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10773503 — Surrogate Endpoint (SUR): Blood pressure
Study 20509919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31300705 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 21999871 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21999871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18471513 — Surrogate Endpoint (SUR): Serum creatinine
Study 16199147 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10709160 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10709160 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 3079487 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11785838 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11785838 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10382572 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18534821 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16313121 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 16313121 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16313121 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16313121 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11789240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8456754 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18446716 — Surrogate Endpoint (SUR): Serum creatinine
Study 10223594 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7884546 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26864092 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16278615 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16278615 — Surrogate Endpoint (SUR): Blood pressure
Study 12086758 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7622910 — Safety Biomarker (SAF): Interleukin 1
Study 7622910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31153659 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28550081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28550081 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 8831316 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 26655803 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20663998 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 22551881 — Surrogate Endpoint (SUR): Bone mineral density
Study 16387150 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29466786 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 29466786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23896389 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 18849616 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 17093147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 15269141 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 10554767 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23064476 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23064476 — Predictive Biomarker (PRD): Hormone receptor
Study 23064476 — Surrogate Endpoint (SUR): Bone mineral density
Study 27567897 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 27567897 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 27567897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27567897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25093868 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22382523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20669671 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 18772061 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15944842 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15944842 — Surrogate Endpoint (SUR): Blood pressure
Study 8898511 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 17351155 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17351155 — Surrogate Endpoint (SUR): Blood pressure
Study 17351155 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7835813 — Predictive Biomarker (PRD): APRT mRNA
Genes: APRT
Study 27651039 — Surrogate Endpoint (SUR): Blood pressure
Study 20082712 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 20082712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15632210 — Predictive Biomarker (PRD): SH2D1A mRNA
Genes: SH2D1A; DSHP; SAP
Study 8754401 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29691288 — Surrogate Endpoint (SUR): Blood pressure
Study 6204142 — Surrogate Endpoint (SUR): Blood pressure
Study 29713133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31431562 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23362174 — Surrogate Endpoint (SUR): Blood pressure
Study 21372569 — Predictive Biomarker (PRD): TMPRSS11D mRNA
Genes: TMPRSS11D; HAT
Study 25872610 — Surrogate Endpoint (SUR): Blood pressure
Study 25872610 — Surrogate Endpoint (SUR): Serum creatinine
Study 16828295 — Surrogate Endpoint (SUR): Serum creatinine
Study 7900628 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30702517 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26678938 — Surrogate Endpoint (SUR): Blood pressure
Study 16688094 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9255270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9255270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9255270 — Surrogate Endpoint (SUR): Serum sodium
Study 8510386 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29476677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18624972 — Surrogate Endpoint (SUR): Bone mineral density
Study 25002161 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11577951 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 8051381 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31997704 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31958773 — Surrogate Endpoint (SUR): Blood pressure
Study 31958773 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17093248 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9506734 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30466306 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 29343693 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11882468 — Surrogate Endpoint (SUR): Bone mineral density
Study 8574231 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2278377 — Surrogate Endpoint (SUR): Blood pressure
Study 28272228 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24713310 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 22797188 — Surrogate Endpoint (SUR): Bone mineral density
Study 20680681 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20680681 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 20680681 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20680681 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9718289 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 19187616 — Surrogate Endpoint (SUR): Blood pressure
Study 16306073 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 12201832 — Predictive Biomarker (PRD): Hormone receptor
Study 12201832 — Surrogate Endpoint (SUR): Bone mineral density
Study 24316262 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24281396 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 3215041 — Surrogate Endpoint (SUR): Blood pressure
Study 28508306 — Surrogate Endpoint (SUR): Blood pressure
Study 25103271 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12827224 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 12827224 — Surrogate Endpoint (SUR): Bone mineral density
Study 7963512 — Surrogate Endpoint (SUR): Blood pressure
Study 16361671 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 16361671 — Predictive Biomarker (PRD): ITSN2 mRNA
Genes: ITSN2; KIAA1256; SH3D1B; SWAP
Study 25302624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21663632 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16684702 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 24500540 — Surrogate Endpoint (SUR): Bone mineral density
Study 27731374 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 27731374 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 27731374 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 15562385 — Surrogate Endpoint (SUR): Bone mineral density
Study 15562385 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 8558148 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8558148 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 3931495 — Surrogate Endpoint (SUR): Blood pressure
Study 27618854 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26195199 — Predictive Biomarker (PRD): PPP1R13L mRNA
Genes: PPP1R13L; IASPP; NKIP1; PPP1R13BL; RAI
Study 20529333 — Predictive Biomarker (PRD): ALPK3 mRNA
Genes: ALPK3; KIAA1330; MAK
Study 12814389 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 31610946 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 26297055 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25599775 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19067673 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19067673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17985060 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 15784478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11860726 — Surrogate Endpoint (SUR): Bone mineral density
Study 7576678 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30318190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8582220 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 43255 — Surrogate Endpoint (SUR): Blood pressure
Study 21851353 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20706107 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11936532 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 10464004 — Surrogate Endpoint (SUR): Blood pressure
Study 26275480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16768837 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 15606633 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9539303 — Surrogate Endpoint (SUR): Serum testosterone
Study 19015347 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16785153 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16785153 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16785153 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 9423751 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3310771 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21858735 — Surrogate Endpoint (SUR): Blood pressure
Study 2059396 — Surrogate Endpoint (SUR): Blood pressure
Study 24457632 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30504569 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30504569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30504569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30504569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20619837 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 12895320 — Monitoring Biomarker (MOI): HBV DNA
Study 29266804 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29266804 — Surrogate Endpoint (SUR): Blood pressure
Study 29266804 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22434523 — Surrogate Endpoint (SUR): Bone mineral density
Study 8668568 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8668568 — Surrogate Endpoint (SUR): Blood pressure
Study 29887537 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27941179 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24561815 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 24561815 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22585532 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22585532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22585532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6777109 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28209343 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 15831540 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7530585 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15655271 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15655271 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8607590 — Surrogate Endpoint (SUR): Blood pressure
Study 22550052 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22550052 — Surrogate Endpoint (SUR): Blood pressure
Study 10330958 — Surrogate Endpoint (SUR): Serum creatinine
Study 8792953 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28105731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28105731 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28105731 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 23209111 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 9447855 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2757771 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11978259 — Surrogate Endpoint (SUR): Blood pressure
Study 11978259 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24486732 — Surrogate Endpoint (SUR): Blood pressure
Study 19095139 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19095139 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19095139 — Surrogate Endpoint (SUR): Blood pressure
Study 25410653 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19496838 — Surrogate Endpoint (SUR): Bacterial count
Study 1483494 — Surrogate Endpoint (SUR): Blood pressure
Study 24657003 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16087788 — Surrogate Endpoint (SUR): Blood pressure
Study 29145839 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10860192 — Surrogate Endpoint (SUR): Blood pressure
Study 9217378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24418570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18397984 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16231254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10701818 — Surrogate Endpoint (SUR): Blood pressure
Study 9347681 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9347681 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8516490 — Surrogate Endpoint (SUR): Blood pressure
Study 14626750 — Surrogate Endpoint (SUR): Blood pressure
Study 14626750 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14626750 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30040242 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 20659607 — Surrogate Endpoint (SUR): Blood pressure
Study 15834297 — Surrogate Endpoint (SUR): Blood pressure
Study 8699839 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8699839 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8699839 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1760713 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 1760713 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6291361 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6291361 — Surrogate Endpoint (SUR): Blood pressure
Study 28748386 — Surrogate Endpoint (SUR): Bone mineral density
Study 22898037 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22898037 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF