TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21597204 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 25784663 — Surrogate Endpoint (SUR): Blood pressure
Study 16011136 — Surrogate Endpoint (SUR): Blood pressure
Study 10090355 — Surrogate Endpoint (SUR): Blood pressure
Study 2148502 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9551674 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9551674 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26216164 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 25773566 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28860174 — Surrogate Endpoint (SUR): Blood pressure
Study 26212437 — Monitoring Biomarker (MOI): HBV DNA
Study 10983914 — Surrogate Endpoint (SUR): Bone mineral density
Study 17606955 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23707824 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 18423977 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11191543 — Safety Biomarker (SAF): Interleukin 12
Study 20473184 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17619534 — Monitoring Biomarker (MOI): HBV DNA
Study 8931610 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1347803 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 27775778 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10593347 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10593347 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31237336 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31237336 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31237336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28527420 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28527420 — Predictive Biomarker (PRD): Hormone receptor
Study 21519752 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 21519752 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21519752 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 18297438 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14649206 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31505051 — Surrogate Endpoint (SUR): Blood pressure
Study 23406826 — Predictive Biomarker (PRD): BOC mRNA
Genes: BOC; UNQ604/PRO1190
Study 26966823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15368546 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 31315868 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27163503 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 27163503 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 20377423 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 16154480 — Surrogate Endpoint (SUR): Blood pressure
Study 27159624 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24702172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18570058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18570058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18570058 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10978257 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 10978257 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 10978257 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8986917 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8986917 — Surrogate Endpoint (SUR): Blood pressure
Study 26643786 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 23934539 — Predictive Biomarker (PRD): SPTB mRNA
Genes: SPTB; SPTB1
Study 20560291 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15850603 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 15850603 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15850603 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15850603 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25212749 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 27676275 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 27676275 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23808885 — Surrogate Endpoint (SUR): Blood pressure
Study 20528880 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17214993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9077376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28921338 — Surrogate Endpoint (SUR): Bone mineral density
Study 18068064 — Surrogate Endpoint (SUR): Serum creatinine
Study 23751938 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11330505 — Surrogate Endpoint (SUR): Blood pressure
Study 11330505 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11330505 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9208964 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 6833466 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 31054101 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 10381673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10381673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 6159902 — Surrogate Endpoint (SUR): Blood pressure
Study 28036350 — Predictive Biomarker (PRD): FOXG1 mRNA
Genes: FOXG1; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; FOXG1A; FOXG1B; FOXG1C
Study 25446376 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 25446376 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2012087 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2012087 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31910877 — Surrogate Endpoint (SUR): Blood pressure
Study 27143858 — Predictive Biomarker (PRD): ADCY10 mRNA
Genes: ADCY10; SAC
Study 22306735 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22306735 — Predictive Biomarker (PRD): Hormone receptor
Study 22306735 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7804477 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3049118 — Surrogate Endpoint (SUR): Blood pressure
Study 22146674 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 22146674 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8378244 — Safety Biomarker (SAF): DRD2
Study 29587801 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 24664172 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24664172 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 24664172 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 22466551 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 27044318 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 25708866 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30450368 — Surrogate Endpoint (SUR): Blood pressure
Study 26025792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21675956 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 17134351 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27130369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27130369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 27130369 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27130369 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 27130369 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24059271 — Surrogate Endpoint (SUR): Serum creatinine
Study 1730902 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18495737 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15888509 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12560439 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10836329 — Surrogate Endpoint (SUR): Bone mineral density
Study 7024767 — Surrogate Endpoint (SUR): Blood pressure
Study 24382482 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28489468 — Predictive Biomarker (PRD): TAAR1 mRNA
Genes: TAAR1; TA1; TAR1; TRAR1
Study 28489468 — Predictive Biomarker (PRD): TAAR9 mRNA
Genes: TAAR9; TA3; TAR3; TRAR3
Study 23953101 — Predictive Biomarker (PRD): PBK mRNA
Genes: PBK; TOPK
Study 21787184 — Surrogate Endpoint (SUR): Serum sodium
Study 21787184 — Surrogate Endpoint (SUR): Blood pressure
Study 26473751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19838638 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17936861 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 7026794 — Surrogate Endpoint (SUR): Blood pressure
Study 28403531 — Surrogate Endpoint (SUR): Blood pressure
Study 25733639 — Surrogate Endpoint (SUR): Blood pressure
Study 24393375 — Predictive Biomarker (PRD): FAIM2 mRNA
Genes: FAIM2; KIAA0950; LFG; LFG2; NMP35; TMBIM2
Study 16283605 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 7467379 — Surrogate Endpoint (SUR): Blood pressure
Study 15155712 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 11268267 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11268267 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 11268267 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 26483357 — Surrogate Endpoint (SUR): Blood pressure
Study 7149870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30566166 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25349296 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 7527326 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7527326 — Surrogate Endpoint (SUR): Blood pressure
Study 12900738 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30170424 — Safety Biomarker (SAF): Hyaluronic acid
Study 28850535 — Predictive Biomarker (PRD): MPG mRNA
Genes: MPG; AAG; ANPG; MID1
Study 15694942 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 15694942 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15694942 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6756273 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27048949 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20140523 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12600722 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8858268 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27058799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27058799 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17959539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17959539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15871189 — Surrogate Endpoint (SUR): Blood pressure
Study 10720857 — Surrogate Endpoint (SUR): Blood pressure
Study 9368810 — Surrogate Endpoint (SUR): Blood pressure
Study 9368810 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18484415 — Surrogate Endpoint (SUR): Blood pressure
Study 16368837 — Surrogate Endpoint (SUR): Blood pressure
Study 14576510 — Surrogate Endpoint (SUR): Blood pressure
Study 19671948 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 8427664 — Surrogate Endpoint (SUR): Blood pressure
Study 18525491 — Surrogate Endpoint (SUR): Bone mineral density
Study 28941144 — Surrogate Endpoint (SUR): Serum creatinine
Study 15975149 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23121473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20453627 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18822982 — Surrogate Endpoint (SUR): Serum uric acid
Study 10526698 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7839425 — Surrogate Endpoint (SUR): Serum creatinine
Study 2495049 — Surrogate Endpoint (SUR): Blood pressure
Study 7043304 — Surrogate Endpoint (SUR): Blood pressure
Study 18836704 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 17505072 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 14871425 — Surrogate Endpoint (SUR): Serum uric acid
Study 8021761 — Predictive Biomarker (PRD): Liver iron
Study 28109266 — Surrogate Endpoint (SUR): Blood pressure
Study 26516910 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 22030782 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22030782 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1736759 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6474360 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29732731 — Predictive Biomarker (PRD): LPAR1 mRNA
Genes: LPAR1; EDG2; LPA1
Study 12840089 — Surrogate Endpoint (SUR): Blood pressure
Study 30764582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30764582 — Surrogate Endpoint (SUR): Blood pressure
Study 30213037 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25089931 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study 20830731 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 20830731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15850080 — Surrogate Endpoint (SUR): Blood pressure
Study 27681702 — Predictive Biomarker (PRD): CTRC mRNA
Genes: CTRC; CLCR
Study 21465735 — Surrogate Endpoint (SUR): Serum creatinine
Study 8936563 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23482473 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23482473 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22322357 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 11850711 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25697576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25697576 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25697576 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25697576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25697576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20085937 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20085937 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18574759 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 15983245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15983245 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11957789 — Safety Biomarker (SAF): Reactive oxygen species
Study 30842160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30842160 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 30842160 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30842160 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 7804511 — Surrogate Endpoint (SUR): Blood pressure
Study 7804511 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26041459 — Surrogate Endpoint (SUR): Blood pressure
Study 22963833 — Surrogate Endpoint (SUR): Blood pressure
Study 24432626 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21668635 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 21897336 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 16492692 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16492692 — Surrogate Endpoint (SUR): Bone mineral density
Study 22704412 — Surrogate Endpoint (SUR): Serum creatinine
Study 22704412 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22704412 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9890391 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 8808232 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30284597 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26296296 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 7942055 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7942055 — Surrogate Endpoint (SUR): Blood pressure
Study 23108496 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22133036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8236142 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8236142 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27843051 — Surrogate Endpoint (SUR): Blood pressure
Study 27074034 — Surrogate Endpoint (SUR): Blood pressure
Study 17583098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 22370319 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 15033251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11695068 — Surrogate Endpoint (SUR): Bone mineral density
Study 27576370 — Predictive Biomarker (PRD): Liver iron
Study 30640138 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30640138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28431432 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 25510442 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15492182 — Safety Biomarker (SAF): Hyaluronic acid
Study 3802717 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 3802717 — Surrogate Endpoint (SUR): Blood pressure
Study 12955553 — Surrogate Endpoint (SUR): Blood pressure
Study 9343031 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 17716544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17716544 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9490235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28318759 — Predictive Biomarker (PRD): ASAH1 mRNA
Genes: ASAH1; ASAH; HSD-33; HSD33
Study 18074149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22097197 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 7900949 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1999714 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31476451 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 28634644 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 15963096 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10321421 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 8921782 — Surrogate Endpoint (SUR): Blood pressure
Study 27696727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27696727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23788270 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15352908 — Surrogate Endpoint (SUR): Bone mineral density
Study 12161007 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21951464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21951464 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21951464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16769945 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 15050490 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 8387085 — Surrogate Endpoint (SUR): Blood pressure
Study 25042931 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12812864 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 10754621 — Surrogate Endpoint (SUR): Blood pressure
Study 1639464 — Surrogate Endpoint (SUR): Blood pressure
Study 6539613 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12081158 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell