TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00963053 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01317173 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01459900 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00002888 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04111224 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study NCT02268734 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT02268734 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02268734 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT02268734 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02268734 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00205335 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01463059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02301065 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT01734070 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03816735 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02431988 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01317758 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01858675 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT00317993 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study NCT01192464 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT03360734 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00005489 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02243111 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00006292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01235026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01235026 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT01235026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04434092 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT01401400 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT03368729 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04865198 — Predictive Biomarker (PRD): RGS14 mRNA
Genes: RGS14
Study NCT04865198 — Predictive Biomarker (PRD): NEURL1 mRNA
Genes: NEURL1; NEURL; NEURL1A; RNF67
Study NCT00171041 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00144352 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03500302 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT00891124 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT02987751 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02623569 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04019353 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04688385 — Predictive Biomarker (PRD): TLR1 mRNA
Genes: TLR1; KIAA0012
Study NCT00724178 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04381520 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04815005 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02826005 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT02542501 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04538742 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02228265 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT02981082 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03942900 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00858169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01681680 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study NCT01681680 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study NCT01681680 — Predictive Biomarker (PRD): SLC47A2 mRNA
Genes: SLC47A2; MATE2
Study NCT02545465 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01153321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04018326 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04018326 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01650766 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT03491761 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00796666 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02227420 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01234051 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT01331486 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00034060 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01568853 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT01554033 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00263341 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study NCT01385917 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00802516 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT01074320 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00231621 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT01360710 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00889135 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study NCT00666640 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01990521 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01990521 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03537846 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02638766 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT02638766 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT03287817 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03287817 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03287817 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03890068 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT03890068 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03890068 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT03601611 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03601611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04192292 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04192292 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study NCT02056808 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03267394 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study NCT03554395 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT00657046 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00297180 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02859428 — Predictive Biomarker (PRD): ATL1 mRNA
Genes: ATL1; GBP3; SPG3A
Study NCT02859428 — Predictive Biomarker (PRD): REEP1 mRNA
Genes: REEP1; C2orf23; SPG31
Study NCT03065010 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00961155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00961155 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT02741323 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT00219063 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02948673 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04059302 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02190994 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02190994 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02190994 — Surrogate Endpoint (SUR): Urine free cortisol
Study NCT04086511 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01724723 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01545401 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01752244 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT04563208 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01639885 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT04392765 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01712659 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study NCT01712659 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT01712659 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00526838 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study NCT00526838 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00526838 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02932527 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT00526500 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT02417519 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT05681975 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00707759 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00707759 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT00707759 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT04468139 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01200589 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01303679 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02525471 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00076154 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03095001 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04662099 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT02518789 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study NCT04201782 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT00386139 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01291420 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT01917149 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03062969 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT00261352 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01815762 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00083213 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02174666 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02913482 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT02219789 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02219789 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01058993 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT00926627 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT02979275 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04437368 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03748992 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT05800418 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05800418 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03814746 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02465853 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02760277 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02118909 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02118909 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT03478631 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01751438 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT00976872 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01803412 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03266809 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02516332 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02482168 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT00058045 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01775475 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03690583 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00662090 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study NCT04767594 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04767594 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00687687 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT00053560 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03994133 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02311660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02688881 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT01171807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01033032 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04172259 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04030390 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04346017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04346017 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study NCT04346017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01611142 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study NCT01611142 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study NCT01611142 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study NCT02947087 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT01066221 — Safety Biomarker (SAF): Glutamate dehydrogenase
Study NCT00495729 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02336607 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00730275 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00371592 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study NCT01809821 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04437901 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01015547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04357444 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01650558 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04175431 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03710473 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02387957 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00340366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01770106 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01590589 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT05052034 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05052034 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02441231 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01607489 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01009151 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02280369 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00809484 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00809484 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03596866 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05786703 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03236675 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study NCT03236675 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03236675 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01034605 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT02090036 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT01856868 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT00148109 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00148109 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00503100 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT00503100 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT03269916 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00495105 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04536545 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT01269528 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study NCT03492762 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT02724098 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00659178 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT01302860 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study NCT03111511 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01775124 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02440945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02806648 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study NCT03071263 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03702231 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04277182 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04277182 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03306589 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00001750 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00973557 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00973557 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02245633 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT02245633 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02484053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02843906 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01588873 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT01588873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00653523 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02010853 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study NCT03847844 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02048332 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02217124 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001782 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT03510572 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03403582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03403582 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02274571 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02112136 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT02112136 — Predictive Biomarker (PRD): PKD2 mRNA
Genes: PKD2; TRPP2
Study NCT02112136 — Safety Biomarker (SAF): Uromodulin
Genes: UMOD
Study NCT03676075 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT03592667 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00143676 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00143676 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00467285 — Surrogate Endpoint (SUR): Bone mineral density