TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16249540 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 8240197 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30514741 — Surrogate Endpoint (SUR): Serum creatinine
Study 16567272 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10892822 — Surrogate Endpoint (SUR): Blood pressure
Study 14731163 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 9392500 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 3048870 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 31790692 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 30454001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12957426 — Safety Biomarker (SAF): Reactive oxygen species
Study 31575375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31575375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25253123 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30400372 — Surrogate Endpoint (SUR): Blood pressure
Study 26524933 — Predictive Biomarker (PRD): SLMAP mRNA
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 26524933 — Surrogate Endpoint (SUR): Blood pressure
Study 22295814 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 16022023 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12446187 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 30325703 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26324362 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 20466200 — Surrogate Endpoint (SUR): Serum creatinine
Study 20466200 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18419497 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12545081 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29352007 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27501833 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15077100 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31138085 — Surrogate Endpoint (SUR): Blood pressure
Study 24191893 — Surrogate Endpoint (SUR): Serum creatinine
Study 10679534 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29727369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29727369 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 7738941 — Surrogate Endpoint (SUR): Serum creatinine
Study 17368065 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 2563788 — Monitoring Biomarker (MOI): HBV DNA
Study 29797689 — Predictive Biomarker (PRD): STIM1 mRNA
Genes: STIM1; GOK
Study 29797689 — Predictive Biomarker (PRD): STIM2 mRNA
Genes: STIM2; KIAA1482
Study 20624256 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30487209 — Surrogate Endpoint (SUR): Blood pressure
Study 25349205 — Surrogate Endpoint (SUR): Serum creatinine
Study 15385360 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30935461 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 31644357 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 31644357 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23672597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23672597 — Surrogate Endpoint (SUR): Blood pressure
Study 11490238 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9550628 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9550628 — Surrogate Endpoint (SUR): Blood pressure
Study 29474302 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27861249 — Surrogate Endpoint (SUR): Blood pressure
Study 9222805 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16542292 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16542292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15978302 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8598547 — Predictive Biomarker (PRD): SLC1A5 mRNA
Genes: SLC1A5; ASCT2; M7V1; RDR; RDRC
Study 31801245 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 9077497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22465317 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22465317 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20009770 — Surrogate Endpoint (SUR): Blood pressure
Study 20009770 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12422152 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7006544 — Surrogate Endpoint (SUR): Blood pressure
Study 31726963 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 11120458 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9105164 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 2951824 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29869044 — Predictive Biomarker (PRD): NOVA2 mRNA
Genes: NOVA2; ANOVA; NOVA3
Study 25535146 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20201624 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 10080400 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8530600 — Surrogate Endpoint (SUR): Serum testosterone
Study 8530600 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2009248 — Surrogate Endpoint (SUR): Blood pressure
Study 28806532 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 18261355 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 18261355 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18261355 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18261355 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15207952 — Surrogate Endpoint (SUR): Blood pressure
Study 11810777 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1099491 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25153411 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23783252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8222650 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 8222650 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30919948 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 22191012 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 22191012 — Surrogate Endpoint (SUR): Blood pressure
Study 30453494 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30453494 — Surrogate Endpoint (SUR): Serum uric acid
Study 28306134 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28306134 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 28306134 — Surrogate Endpoint (SUR): Blood pressure
Study 26011955 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9506757 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29852208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28231596 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23425550 — Surrogate Endpoint (SUR): Bone mineral density
Study 21839757 — Surrogate Endpoint (SUR): Blood pressure
Study 19453998 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19453998 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 15577539 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28332360 — Monitoring Biomarker (MOI): HBV DNA
Study 24660605 — Monitoring Biomarker (MOI): Procalcitonin
Study 24660605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24660605 — Safety Biomarker (SAF): IL-6 and IL-10
Study 24660605 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24660605 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 21224045 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 21224045 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 25137296 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 25137296 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 25137296 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 25137296 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25137296 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23261122 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23261122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28701674 — Surrogate Endpoint (SUR): Blood pressure
Study 26329806 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 18475166 — Surrogate Endpoint (SUR): Blood pressure
Study 14521253 — Surrogate Endpoint (SUR): Blood pressure
Study 12353420 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3259441 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16594908 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 10488974 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30959189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28662406 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26302914 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26302914 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24206407 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24206407 — Surrogate Endpoint (SUR): Blood pressure
Study 18636232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18636232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16556716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16556716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16556716 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16556716 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29786471 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 27174221 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 30811541 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 30811541 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26261259 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26261259 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22906565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29713086 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 2571726 — Surrogate Endpoint (SUR): Blood pressure
Study 28431010 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11120398 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9662230 — Surrogate Endpoint (SUR): Blood pressure
Study 25252296 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 18337343 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 18337343 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 17181919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9187782 — Surrogate Endpoint (SUR): Blood pressure
Study 22235107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22235107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2510652 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 2510652 — Surrogate Endpoint (SUR): Blood pressure
Study 18465341 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 18465341 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29858688 — Surrogate Endpoint (SUR): Blood pressure
Study 29858688 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29953191 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 20056845 — Surrogate Endpoint (SUR): Blood pressure
Study 18230747 — Surrogate Endpoint (SUR): Blood pressure
Study 14974733 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10990166 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10990166 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31824507 — Predictive Biomarker (PRD): KLRC2 mRNA
Genes: KLRC2; NKG2C
Study 31824507 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 28795416 — Surrogate Endpoint (SUR): Blood pressure
Study 21633074 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 11717600 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10366113 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 22094352 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 19862609 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18067807 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 11774289 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 18957505 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 18957505 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 7092330 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9736567 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25168278 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 25168278 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 20513826 — Surrogate Endpoint (SUR): Blood pressure
Study 8247075 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 3102089 — Surrogate Endpoint (SUR): Serum creatinine
Study 21933332 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 15944165 — Surrogate Endpoint (SUR): Bone mineral density
Study 31651927 — Surrogate Endpoint (SUR): Blood pressure
Study 30728886 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 30728886 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 30728886 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 30728886 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 30728886 — Safety Biomarker (SAF): Reactive oxygen species
Study 21674629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21674629 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12225709 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 7624465 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24721888 — Surrogate Endpoint (SUR): Total kidney volume
Study 22397390 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20134405 — Surrogate Endpoint (SUR): Blood pressure
Study 1948212 — Surrogate Endpoint (SUR): Blood pressure
Study 19968743 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 18356607 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1783249 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1783249 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29883497 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29883497 — Surrogate Endpoint (SUR): Blood pressure
Study 27998854 — Surrogate Endpoint (SUR): Blood pressure
Study 10365734 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22435244 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22435244 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22435244 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22435244 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8607727 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8607727 — Surrogate Endpoint (SUR): Blood pressure
Study 30546024 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19937367 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19937367 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 19937367 — Safety Biomarker (SAF): BDNF
Study 19937367 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12270990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12270990 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12270990 — Surrogate Endpoint (SUR): Blood pressure
Study 7645037 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19447249 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11345223 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8029809 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 27966237 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24225201 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 17828747 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16796788 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10078539 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 10078539 — Surrogate Endpoint (SUR): Blood pressure
Study 10078539 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 1708984 — Surrogate Endpoint (SUR): Blood pressure
Study 1708984 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30361675 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 24991995 — Surrogate Endpoint (SUR): Blood pressure
Study 15952173 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 30563778 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 24041337 — Surrogate Endpoint (SUR): Bone mineral density
Study 21620725 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12082261 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12082261 — Surrogate Endpoint (SUR): Blood pressure
Study 7011110 — Surrogate Endpoint (SUR): Blood pressure
Study 12436341 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9831697 — Surrogate Endpoint (SUR): Blood pressure
Study 2918846 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 2918846 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 2918846 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 26678626 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 26678626 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26678626 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18442621 — Surrogate Endpoint (SUR): Blood pressure
Study 18442621 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9506401 — Predictive Biomarker (PRD): ARHGAP32 mRNA
Genes: ARHGAP32; GRIT; KIAA0712; RICS
Study 2832575 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2832575 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2832575 — Surrogate Endpoint (SUR): Blood pressure
Study 26244602 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17014562 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17014562 — Surrogate Endpoint (SUR): Blood pressure
Study 7690382 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7690382 — Surrogate Endpoint (SUR): Blood pressure
Study 19707144 — Surrogate Endpoint (SUR): Blood pressure
Study 8906369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8906369 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30232854 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18388038 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18388038 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10336532 — Surrogate Endpoint (SUR): Blood pressure
Study 8938155 — Monitoring Biomarker (MOI): HBV DNA
Study 22366365 — Safety Biomarker (SAF): Hyaluronic acid
Study 30467071 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 26022314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11230588 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8435030 — Surrogate Endpoint (SUR): Blood pressure
Study 30630795 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20197284 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 20197284 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20197284 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25013370 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 25013370 — Surrogate Endpoint (SUR): Blood pressure
Study 19261771 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19261771 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19261771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19261771 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402