TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25642640 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 14608246 — Surrogate Endpoint (SUR): Blood pressure
Study 31732062 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 31732062 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22814748 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22814748 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22814748 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15791171 — Surrogate Endpoint (SUR): Blood pressure
Study 10505742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10505742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29950229 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 29950229 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 29950229 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 22707187 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22707187 — Surrogate Endpoint (SUR): Blood pressure
Study 20540652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12450902 — Surrogate Endpoint (SUR): Serum calcium
Study 29504416 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 14564328 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 8844445 — Predictive Biomarker (PRD): NAPA mRNA
Genes: NAPA; SNAPA
Study 24695100 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9440092 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31126582 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31126582 — Surrogate Endpoint (SUR): Blood pressure
Study 28288636 — Surrogate Endpoint (SUR): Blood pressure
Study 19602907 — Surrogate Endpoint (SUR): Blood pressure
Study 12048274 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 3549319 — Surrogate Endpoint (SUR): Serum creatinine
Study 29573263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27687410 — Surrogate Endpoint (SUR): Blood pressure
Study 22249941 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22249941 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16099227 — Surrogate Endpoint (SUR): Bone mineral density
Study 3324612 — Surrogate Endpoint (SUR): Blood pressure
Study 23437796 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 21701167 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 21701167 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 16449511 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16449511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9101388 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20458443 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 10362048 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7595717 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7425833 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7425833 — Surrogate Endpoint (SUR): Blood pressure
Study 15932790 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22839442 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22839442 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 22942337 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11766711 — Surrogate Endpoint (SUR): Blood pressure
Study 2139916 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 631536 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 17711706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 17711706 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17711706 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 17711706 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 28405611 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 19332201 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11320105 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11320105 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11320105 — Surrogate Endpoint (SUR): Bone mineral density
Study 2835892 — Surrogate Endpoint (SUR): Blood pressure
Study 30776393 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30776393 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 18926856 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10701059 — Surrogate Endpoint (SUR): Serum calcium
Study 9377171 — Surrogate Endpoint (SUR): Blood pressure
Study 9377171 — Safety Biomarker (SAF): Interleukin 1
Study 9377171 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9377171 — Surrogate Endpoint (SUR): Serum creatinine
Study 27107540 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27107540 — Surrogate Endpoint (SUR): Blood pressure
Study 18761243 — Surrogate Endpoint (SUR): Blood pressure
Study 28004335 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 16251566 — Surrogate Endpoint (SUR): Blood pressure
Study 2937598 — Surrogate Endpoint (SUR): Blood pressure
Study 2937598 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22310472 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 18827176 — Surrogate Endpoint (SUR): Blood pressure
Study 18827176 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11392163 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 26884585 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15989829 — Surrogate Endpoint (SUR): Blood pressure
Study 12466335 — Surrogate Endpoint (SUR): Serum testosterone
Study 18388156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30098513 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 30098513 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30098513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30098513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30098513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24895288 — Surrogate Endpoint (SUR): Serum sodium
Study 11922229 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 23369425 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23369425 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19584192 — Surrogate Endpoint (SUR): Bone mineral density
Study 15019156 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28001306 — Surrogate Endpoint (SUR): Blood pressure
Study 24253812 — Predictive Biomarker (PRD): SMUG1 mRNA
Genes: SMUG1
Study 24253812 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 24253812 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 24253812 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24253812 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 24253812 — Predictive Biomarker (PRD): MDM4 mRNA
Genes: MDM4; MDMX
Study 10852275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8385176 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8385176 — Surrogate Endpoint (SUR): Blood pressure
Study 28693484 — Surrogate Endpoint (SUR): Blood pressure
Study 24169120 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8431122 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8431122 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27323348 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 18704485 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29952807 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29952807 — Surrogate Endpoint (SUR): Blood pressure
Study 14735177 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 3281603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23608654 — Surrogate Endpoint (SUR): Blood pressure
Study 23608654 — Safety Biomarker (SAF): MTHFR
Study 21691817 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 21691817 — Surrogate Endpoint (SUR): Bone mineral density
Study 9869019 — Surrogate Endpoint (SUR): Blood pressure
Study 2570582 — Surrogate Endpoint (SUR): Blood pressure
Study 3972525 — Surrogate Endpoint (SUR): Blood pressure
Study 21039720 — Safety Biomarker (SAF): Interleukin 1
Study 12958547 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 10484801 — Surrogate Endpoint (SUR): Blood pressure
Study 6217892 — Surrogate Endpoint (SUR): Blood pressure
Study 29679478 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 26197975 — Surrogate Endpoint (SUR): Blood pressure
Study 16584518 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8644530 — Surrogate Endpoint (SUR): Blood pressure
Study 27577069 — Surrogate Endpoint (SUR): Pathological complete response
Study 22721655 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10695183 — Predictive Biomarker (PRD): RHOF mRNA
Genes: RHOF; ARHF; RIF
Study 30596666 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21691746 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 16524789 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15194374 — Surrogate Endpoint (SUR): Serum creatinine
Study 27933161 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27933161 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 26311225 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 26311225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26311225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30916353 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 28637705 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22689176 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 17119458 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 1904333 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1904333 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28947003 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 23788751 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23788751 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8286206 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29153692 — Surrogate Endpoint (SUR): Blood pressure
Study 26139202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27871575 — Surrogate Endpoint (SUR): Blood pressure
Study 22775448 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22775448 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 22775448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9816716 — Surrogate Endpoint (SUR): Blood pressure
Study 2700113 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2700113 — Surrogate Endpoint (SUR): Blood pressure
Study 29460812 — Surrogate Endpoint (SUR): Blood pressure
Study 24771721 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 24367492 — Predictive Biomarker (PRD): RSF1 mRNA
Genes: RSF1; HBXAP; XAP8
Study 24367492 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 24367492 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 24367492 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21405957 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21405957 — Surrogate Endpoint (SUR): Blood pressure
Study 21405957 — Surrogate Endpoint (SUR): Serum uric acid
Study 14610410 — Surrogate Endpoint (SUR): Bone mineral density
Study 1487923 — Surrogate Endpoint (SUR): Blood pressure
Study 10607709 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10607709 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 10607709 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9194621 — Surrogate Endpoint (SUR): Serum calcium
Study 19300369 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 23213979 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30624753 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 24503952 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22824079 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 2110388 — Predictive Biomarker (PRD): FBN1 mRNA
Genes: FBN1; FBN
Study 25824556 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 21410621 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 19302256 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17298712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1723772 — Surrogate Endpoint (SUR): Blood pressure
Study 28369419 — Surrogate Endpoint (SUR): Bone mineral density
Study 11840351 — Surrogate Endpoint (SUR): Blood pressure
Study 29568104 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 29568104 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 26523730 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 23514767 — Surrogate Endpoint (SUR): Blood pressure
Study 23514767 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 20142600 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20142600 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19198140 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 19198140 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 14523461 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 14523461 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 9359973 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 15653705 — Surrogate Endpoint (SUR): Blood pressure
Study 12375321 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7788204 — Surrogate Endpoint (SUR): Blood pressure
Study 472679 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31386826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31386826 — Surrogate Endpoint (SUR): Blood pressure
Study 17700222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17700222 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11953077 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 18346976 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 25755182 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10414474 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24402390 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 24402390 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12042673 — Safety Biomarker (SAF): MTHFR
Study 7793221 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7793221 — Surrogate Endpoint (SUR): Blood pressure
Study 18490495 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 15941879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1951617 — Surrogate Endpoint (SUR): Blood pressure
Study 9652880 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9652880 — Surrogate Endpoint (SUR): Blood pressure
Study 25604134 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25604134 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23247737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15359398 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 9709393 — Surrogate Endpoint (SUR): Blood pressure
Study 26448381 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 7589035 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7589035 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 6930207 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31044463 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 22696863 — Surrogate Endpoint (SUR): Blood pressure
Study 17393018 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 17393018 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9624598 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7519693 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7519693 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7519693 — Surrogate Endpoint (SUR): Blood pressure
Study 28163068 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 28163068 — Safety Biomarker (SAF): Hyaluronic acid
Study 14627865 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19892055 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19892055 — Surrogate Endpoint (SUR): Blood pressure
Study 30025522 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22475864 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20417423 — Surrogate Endpoint (SUR): Blood pressure
Study 18600492 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 12022177 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29536389 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 24952693 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 17483542 — Surrogate Endpoint (SUR): Blood pressure
Study 16305585 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9794714 — Surrogate Endpoint (SUR): Blood pressure
Study 21792066 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21792066 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 18728037 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9164988 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29429464 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 18536787 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18536787 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12647275 — Predictive Biomarker (PRD): RETN mRNA
Genes: RETN; FIZZ3; HXCP1; RSTN; UNQ407/PRO1199
Study 12647275 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28390970 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 24866478 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 16255987 — Predictive Biomarker (PRD): SOBP mRNA
Genes: SOBP; JXC1
Study 16255987 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 11851659 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 31558473 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 31558473 — Predictive Biomarker (PRD): HRAS mRNA
Genes: HRAS; HRAS1
Study 31558473 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 31558473 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25972054 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 21253725 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11468543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11468543 — Surrogate Endpoint (SUR): Blood pressure
Study 9721802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16421011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16421011 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 16421011 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16421011 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2865677 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29747966 — Surrogate Endpoint (SUR): Bone mineral density
Study 3135392 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19262230 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31253162 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25564570 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 21981453 — Surrogate Endpoint (SUR): Blood pressure
Study 27569438 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27569438 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 18520598 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8690823 — Surrogate Endpoint (SUR): Blood pressure
Study 1686814 — Surrogate Endpoint (SUR): Blood pressure
Study 8579030 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1673284 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31689835 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25546368 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR