TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28506281 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 24038152 — Surrogate Endpoint (SUR): Bone mineral density
Study 16629791 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 25011647 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 25011647 — Surrogate Endpoint (SUR): Blood pressure
Study 25011647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22138360 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 22138360 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17335309 — Surrogate Endpoint (SUR): Blood pressure
Study 27103607 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 20047363 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 1320846 — Surrogate Endpoint (SUR): Serum creatinine
Study 31606362 — Surrogate Endpoint (SUR): Blood pressure
Study 28030534 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 28030534 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 28030534 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 28030534 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 28030534 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 9287227 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8420235 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8420235 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24768239 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24768239 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22476230 — Surrogate Endpoint (SUR): Blood pressure
Study 19235080 — Surrogate Endpoint (SUR): Blood pressure
Study 2337035 — Surrogate Endpoint (SUR): Serum potassium
Study 15314546 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9329410 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30043885 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 19597412 — Surrogate Endpoint (SUR): Blood pressure
Study 31033190 — Predictive Biomarker (PRD): FGD5 mRNA
Genes: FGD5; ZFYVE23
Study 31033190 — Surrogate Endpoint (SUR): Blood pressure
Study 22892323 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22892323 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17673615 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31665935 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 20715737 — Surrogate Endpoint (SUR): Blood pressure
Study 12537186 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 30589829 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23567348 — Surrogate Endpoint (SUR): Blood pressure
Study 3049953 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25604722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25604722 — Surrogate Endpoint (SUR): Blood pressure
Study 20577017 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 7091770 — Surrogate Endpoint (SUR): Blood pressure
Study 30082141 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 25591969 — Surrogate Endpoint (SUR): Blood pressure
Study 8436095 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31884740 — Surrogate Endpoint (SUR): Blood pressure
Study 22556172 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study 20053692 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3075649 — Surrogate Endpoint (SUR): Blood pressure
Study 17893629 — Surrogate Endpoint (SUR): Serum creatinine
Study 17893629 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 17893629 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 29225332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29225332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16865075 — Surrogate Endpoint (SUR): Blood pressure
Study 31626906 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 31626906 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27397921 — Surrogate Endpoint (SUR): Blood pressure
Study 18756885 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10722237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30157532 — Surrogate Endpoint (SUR): Blood pressure
Study 15331124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15331124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9442423 — Surrogate Endpoint (SUR): Probing pocket depth
Study 3232799 — Surrogate Endpoint (SUR): Blood pressure
Study 23558598 — Surrogate Endpoint (SUR): Blood pressure
Study 21108561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21108561 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8124904 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 21769850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16879825 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 27655755 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27655755 — Surrogate Endpoint (SUR): Blood pressure
Study 27655755 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24548977 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 24548977 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15990174 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 17898405 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 31129617 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22573127 — Surrogate Endpoint (SUR): Blood pressure
Study 25986854 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21247480 — Predictive Biomarker (PRD): NOD2 mRNA
Genes: NOD2; CARD15; IBD1
Study 26645254 — Surrogate Endpoint (SUR): Blood pressure
Study 20369615 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20369615 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 26829251 — Surrogate Endpoint (SUR): Blood pressure
Study 17106274 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17106274 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2534412 — Surrogate Endpoint (SUR): Serum potassium
Study 25109699 — Monitoring Biomarker (MOI): HBV DNA
Study 21999662 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 16803911 — Surrogate Endpoint (SUR): Blood pressure
Study 22367794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12480497 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12480497 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12480497 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30238636 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 21226818 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 1417632 — Surrogate Endpoint (SUR): Blood pressure
Study 23573950 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 11224624 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16936704 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 15238771 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9408700 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18565884 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16043985 — Predictive Biomarker (PRD): IRAK1 mRNA
Genes: IRAK1; IRAK
Study 16043985 — Predictive Biomarker (PRD): TRAF6 mRNA
Genes: TRAF6; RNF85
Study 16043985 — Predictive Biomarker (PRD): DPEP1 mRNA
Genes: DPEP1; MDP; RDP
Study 7718459 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7718459 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 7718459 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2381302 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30911274 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study 27451030 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12089223 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 30707970 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22354743 — Surrogate Endpoint (SUR): Bone mineral density
Study 18030230 — Surrogate Endpoint (SUR): Bone mineral density
Study 16219012 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25379688 — Surrogate Endpoint (SUR): Blood pressure
Study 22546837 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 22546837 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19046909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15138163 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30590827 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20884178 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 9493577 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27935240 — Surrogate Endpoint (SUR): Blood pressure
Study 25452012 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 24326421 — Surrogate Endpoint (SUR): Serum testosterone
Study 24326421 — Surrogate Endpoint (SUR): Bone mineral density
Study 15763716 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25627076 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25627076 — Surrogate Endpoint (SUR): Blood pressure
Study 12873621 — Surrogate Endpoint (SUR): Blood pressure
Study 10416877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31149869 — Surrogate Endpoint (SUR): Blood pressure
Study 31149869 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22156352 — Surrogate Endpoint (SUR): Blood pressure
Study 7495240 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 388395 — Surrogate Endpoint (SUR): Blood pressure
Study 388395 — Surrogate Endpoint (SUR): Serum uric acid
Study 388395 — Surrogate Endpoint (SUR): Serum potassium
Study 388395 — Surrogate Endpoint (SUR): Serum creatinine
Study 29352654 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29628560 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25385729 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 25385729 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study 25385729 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 25385729 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 16238909 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16238909 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31556454 — Surrogate Endpoint (SUR): Blood pressure
Study 22878802 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17532398 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 11552002 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19422337 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 16934051 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 16934051 — Surrogate Endpoint (SUR): Blood pressure
Study 1363221 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 1363221 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 1363221 — Surrogate Endpoint (SUR): Blood pressure
Study 30804464 — Surrogate Endpoint (SUR): Blood pressure
Study 23357150 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19874992 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19874992 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28177671 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 28177671 — Safety Biomarker (SAF): Reactive oxygen species
Study 3304386 — Surrogate Endpoint (SUR): Blood pressure
Study 31566845 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18376691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18376691 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11004031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11004031 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 11004031 — Safety Biomarker (SAF): Interleukin 1
Study 11004031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8400072 — Surrogate Endpoint (SUR): Serum creatinine
Study 24382064 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15781736 — Surrogate Endpoint (SUR): Serum creatinine
Study 8663853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8663853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8663853 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 6479183 — Surrogate Endpoint (SUR): Blood pressure
Study 19765954 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15782288 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31740368 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31740368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26040499 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 26040499 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26040499 — Predictive Biomarker (PRD): Hormone receptor
Study 26040499 — Surrogate Endpoint (SUR): Bone mineral density
Study 22142711 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 11413894 — Surrogate Endpoint (SUR): Blood pressure
Study 26485913 — Surrogate Endpoint (SUR): Blood pressure
Study 3401524 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31077827 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31077827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31077827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18993165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18993165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17473825 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 9665110 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9665110 — Safety Biomarker (SAF): Interleukin 12
Study 29166829 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 28131786 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 3416848 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25913848 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 29020995 — Surrogate Endpoint (SUR): Blood pressure
Study 26093812 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8160789 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8160789 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 28987930 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 28583653 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26304935 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 1313549 — Surrogate Endpoint (SUR): Serum creatinine
Study 20647096 — Surrogate Endpoint (SUR): Bacterial count
Study 16028466 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2161058 — Surrogate Endpoint (SUR): Blood pressure
Study 7392541 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7392541 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18570561 — Surrogate Endpoint (SUR): Blood pressure
Study 16092057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6840159 — Surrogate Endpoint (SUR): Blood pressure
Study 31292965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25746039 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 19364966 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20525211 — Surrogate Endpoint (SUR): Blood pressure
Study 20525211 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15148337 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 11389423 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9247759 — Surrogate Endpoint (SUR): Blood pressure
Study 3954127 — Surrogate Endpoint (SUR): Blood pressure
Study 11445756 — Surrogate Endpoint (SUR): Blood pressure
Study 11445756 — Surrogate Endpoint (SUR): Serum creatinine
Study 11445756 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29458447 — Surrogate Endpoint (SUR): Blood pressure
Study 26804607 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 26755382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26755382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25266967 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16392436 — Surrogate Endpoint (SUR): Blood pressure
Study 1284345 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24972708 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17650661 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 12234851 — Safety Biomarker (SAF): Interleukin 12
Study 30729456 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27021357 — Predictive Biomarker (PRD): GNS mRNA
Genes: GNS
Study 25566618 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 22233522 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 16245354 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28889792 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 18167644 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 24499830 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24499830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12904518 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24578471 — Surrogate Endpoint (SUR): Serum creatinine
Study 29383408 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29383408 — Surrogate Endpoint (SUR): Serum calcium
Study 18425398 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16607097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9665269 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 3278434 — Surrogate Endpoint (SUR): Serum creatinine
Study 25769330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25769330 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25769330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12797397 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24525553 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 25588 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 26940151 — Surrogate Endpoint (SUR): Serum uric acid
Study 17293706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17293706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28832441 — Predictive Biomarker (PRD): MVK mRNA
Genes: MVK
Study 23714653 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18451231 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 12153962 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 6767404 — Surrogate Endpoint (SUR): Blood pressure
Study 6767404 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24926949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1