TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18480832 — Surrogate Endpoint (SUR): Blood pressure
Study 10559510 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10559510 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29801398 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 29801398 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 26231884 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 196232 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 26059012 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23852309 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 7511740 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7511740 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7511740 — Surrogate Endpoint (SUR): Blood pressure
Study 11392066 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 1325613 — Surrogate Endpoint (SUR): Blood pressure
Study 6381612 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 23819476 — Surrogate Endpoint (SUR): Blood pressure
Study 12695287 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 9893077 — Surrogate Endpoint (SUR): Bone mineral density
Study 7751429 — Surrogate Endpoint (SUR): Blood pressure
Study 31355456 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31355456 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 31355456 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 31355456 — Predictive Biomarker (PRD): CAMLG mRNA
Genes: CAMLG; CAML; GET2
Study 9503547 — Surrogate Endpoint (SUR): Blood pressure
Study 9503547 — Surrogate Endpoint (SUR): Serum creatinine
Study 9175947 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20167430 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16494640 — Surrogate Endpoint (SUR): Blood pressure
Study 15347114 — Surrogate Endpoint (SUR): Blood pressure
Study 8006520 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20821047 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8422814 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8643419 — Surrogate Endpoint (SUR): Bone mineral density
Study 2145770 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2145770 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31437853 — Surrogate Endpoint (SUR): Blood pressure
Study 27526332 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 26118144 — Surrogate Endpoint (SUR): Blood pressure
Study 10737537 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1332634 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1332634 — Surrogate Endpoint (SUR): Blood pressure
Study 12956739 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9354313 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30237219 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 18055982 — Predictive Biomarker (PRD): Liver iron
Study 16581423 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 16581423 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11556039 — Predictive Biomarker (PRD): Hormone receptor
Study 8669669 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29956886 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20222114 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15812629 — Monitoring Biomarker (MOI): Procalcitonin
Study 15812629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15812629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1941406 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 30929097 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30929097 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23279139 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17065639 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12899797 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 2856773 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2856773 — Surrogate Endpoint (SUR): Blood pressure
Study 14679274 — Safety Biomarker (SAF): Hyaluronic acid
Study 25908462 — Surrogate Endpoint (SUR): Blood pressure
Study 23417664 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 19541717 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19541717 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19541717 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11728145 — Surrogate Endpoint (SUR): Blood pressure
Study 24857251 — Surrogate Endpoint (SUR): Blood pressure
Study 24857251 — Surrogate Endpoint (SUR): Serum creatinine
Study 15797646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15797646 — Surrogate Endpoint (SUR): Blood pressure
Study 15797646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15797646 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 15797646 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 30156654 — Surrogate Endpoint (SUR): Blood pressure
Study 26813471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26813471 — Surrogate Endpoint (SUR): Serum creatinine
Study 20352259 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27236888 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 27236888 — Predictive Biomarker (PRD): ATG12 mRNA
Genes: ATG12; APG12; APG12L
Study 27236888 — Predictive Biomarker (PRD): ATG13 mRNA
Genes: ATG13; KIAA0652
Study 27236888 — Predictive Biomarker (PRD): ATG5 mRNA
Genes: ATG5; APG5L; ASP
Study 22493419 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8087191 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 2676440 — Surrogate Endpoint (SUR): Blood pressure
Study 19701600 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 19701600 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 19701600 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11219479 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11219479 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11219479 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9475657 — Surrogate Endpoint (SUR): Blood pressure
Study 2739019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26297360 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 21324150 — Surrogate Endpoint (SUR): Blood pressure
Study 2421751 — Surrogate Endpoint (SUR): Blood pressure
Study 17923401 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17923401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17923401 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17923401 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 2170885 — Surrogate Endpoint (SUR): Bone mineral density
Study 2170885 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2170885 — Surrogate Endpoint (SUR): Blood pressure
Study 31365280 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 25785441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25785441 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25785441 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8389662 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 29876844 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29876844 — Predictive Biomarker (PRD): SLC35A2 mRNA
Genes: SLC35A2; UGALT; UGT; UGTL
Study 18974717 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10596684 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8537687 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30626285 — Surrogate Endpoint (SUR): Blood pressure
Study 2138237 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22476616 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25694056 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 25694056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19444561 — Surrogate Endpoint (SUR): Serum sodium
Study 17314338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11438316 — Surrogate Endpoint (SUR): Serum testosterone
Study 21813807 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 21813807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16679630 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16679630 — Surrogate Endpoint (SUR): Serum creatinine
Study 28391756 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 23643011 — Surrogate Endpoint (SUR): Blood pressure
Study 25932792 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 16861099 — Surrogate Endpoint (SUR): Blood pressure
Study 12963170 — Surrogate Endpoint (SUR): Bone mineral density
Study 11041396 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 19717399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30919249 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30919249 — Surrogate Endpoint (SUR): Blood pressure
Study 27420976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27420976 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 27420976 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27420976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7718316 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 6345013 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 30628088 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22969203 — Predictive Biomarker (PRD): MOXD1 mRNA
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 19118805 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 2644533 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31418411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7844226 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3142396 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3142396 — Predictive Biomarker (PRD): LAT2 mRNA
Genes: LAT2; LAB; NTAL; WBS15; WBSCR15; WBSCR5; HSPC046
Study 9803988 — Predictive Biomarker (PRD): BLVRA mRNA
Genes: BLVRA; BLVR; BVR
Study 9803988 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 15010066 — Surrogate Endpoint (SUR): Serum creatinine
Study 9683329 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 7885940 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30908574 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 30908574 — Predictive Biomarker (PRD): UGT2B15 mRNA
Genes: UGT2B15; UGT2B8
Study 30908574 — Predictive Biomarker (PRD): SULT1A1 mRNA
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 15806975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15806975 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15806975 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15806975 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21102344 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 16569797 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 1551152 — Surrogate Endpoint (SUR): Blood pressure
Study 18478253 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1646240 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1646240 — Surrogate Endpoint (SUR): Blood pressure
Study 12823907 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 10753983 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10753983 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10753983 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30813694 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18405788 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15888152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24812899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24812899 — Safety Biomarker (SAF): Interleukin 12
Study 15125006 — Surrogate Endpoint (SUR): Bone mineral density
Study 11379380 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 30904595 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30904595 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30022334 — Surrogate Endpoint (SUR): Blood pressure
Study 26174879 — Surrogate Endpoint (SUR): Bone mineral density
Study 22748590 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22748590 — Surrogate Endpoint (SUR): Serum creatinine
Study 19890256 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 16050054 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16050054 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16050054 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14624217 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 14624217 — Safety Biomarker (SAF): MTHFR
Study 1732652 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1732652 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23823716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23823716 — Surrogate Endpoint (SUR): Blood pressure
Study 20018913 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18627001 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 12162932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7326269 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 11673752 — Surrogate Endpoint (SUR): Blood pressure
Study 30954071 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21938889 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 10585174 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 2053167 — Surrogate Endpoint (SUR): Blood pressure
Study 31578205 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 31578205 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 31578205 — Predictive Biomarker (PRD): ZRSR2 mRNA
Genes: ZRSR2; U2AF1-RS2; U2AF1L2; U2AF1RS2; URP
Study 18235123 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 1846723 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31925799 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31925799 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11850709 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26539650 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26539650 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11144434 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 26197707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12850126 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 25194505 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 20822027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20822027 — Safety Biomarker (SAF): IL-6 and IL-10
Study 7571220 — Surrogate Endpoint (SUR): Blood pressure
Study 7571220 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2076734 — Surrogate Endpoint (SUR): Blood pressure
Study 28538380 — Surrogate Endpoint (SUR): Serum calcium
Study 28538380 — Surrogate Endpoint (SUR): Blood pressure
Study 23457307 — Surrogate Endpoint (SUR): Blood pressure
Study 21879181 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19453516 — Surrogate Endpoint (SUR): Blood pressure
Study 8384187 — Surrogate Endpoint (SUR): Blood pressure
Study 30885221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30885221 — Surrogate Endpoint (SUR): Blood pressure
Study 30885221 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30885221 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17917927 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11848168 — Surrogate Endpoint (SUR): Blood pressure
Study 2298472 — Surrogate Endpoint (SUR): Blood pressure
Study 30981681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30981681 — Surrogate Endpoint (SUR): Blood pressure
Study 27994300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27994300 — Surrogate Endpoint (SUR): Serum creatinine
Study 22726916 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 16575135 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10194656 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6763175 — Safety Biomarker (SAF): Hyaluronic acid
Study 28183140 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 28183140 — Monitoring Biomarker (MOI): Cell-free DNA
Study 23337728 — Surrogate Endpoint (SUR): Bone mineral density
Study 21266948 — Surrogate Endpoint (SUR): Blood pressure
Study 21266948 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15322457 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8164925 — Surrogate Endpoint (SUR): Blood pressure
Study 3211806 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 3211806 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31430623 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 18768332 — Surrogate Endpoint (SUR): Blood pressure
Study 25429853 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25429853 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30027669 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 26336919 — Surrogate Endpoint (SUR): Serum creatinine
Study 26336919 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 26336919 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 26336919 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24252587 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 29523800 — Predictive Biomarker (PRD): TREM2 mRNA
Genes: TREM2
Study 26209090 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 22961907 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 22961907 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 22961907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27729394 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23989522 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26153128 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23759268 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23759268 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25249429 — Surrogate Endpoint (SUR): Blood pressure
Study 24660233 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 24660233 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 7843446 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 2646004 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 2646004 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 22315776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19919399 — Surrogate Endpoint (SUR): Blood pressure
Study 19712802 — Surrogate Endpoint (SUR): Serum testosterone
Study 17961387 — Surrogate Endpoint (SUR): Blood pressure
Study 21219394 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15657568 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 2878680 — Surrogate Endpoint (SUR): Blood pressure
Study 2878680 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31594394 — Predictive Biomarker (PRD): HR mRNA
Genes: HR