TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18219225 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9285437 — Predictive Biomarker (PRD): PLXNB1 mRNA
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 20185037 — Surrogate Endpoint (SUR): Serum sodium
Study 10852140 — Surrogate Endpoint (SUR): Blood pressure
Study 8813790 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8813790 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31919136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31919136 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 31919136 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study 31919136 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 11143848 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11143848 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9002327 — Surrogate Endpoint (SUR): Serum sodium
Study 25462535 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20003828 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10680454 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27655522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24563517 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 24563517 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 26213789 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 12924536 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31754687 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 29886466 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10496259 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 6994779 — Surrogate Endpoint (SUR): Blood pressure
Study 16036033 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 11059947 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11059947 — Surrogate Endpoint (SUR): Blood pressure
Study 8039761 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 3090512 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 26867764 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 10221490 — Surrogate Endpoint (SUR): Serum creatinine
Study 10221490 — Surrogate Endpoint (SUR): Serum uric acid
Study 2145872 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2145872 — Surrogate Endpoint (SUR): Blood pressure
Study 23651756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23651756 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11217909 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11217909 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 29665351 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26713528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26713528 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 1405330 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3874774 — Surrogate Endpoint (SUR): Blood pressure
Study 25436797 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 12681866 — Surrogate Endpoint (SUR): Blood pressure
Study 19565176 — Surrogate Endpoint (SUR): Bone mineral density
Study 1664792 — Surrogate Endpoint (SUR): Blood pressure
Study 20716629 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 20716629 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19761888 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19761888 — Surrogate Endpoint (SUR): Blood pressure
Study 19761888 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15361814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15361814 — Surrogate Endpoint (SUR): Blood pressure
Study 15361814 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15361814 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11028260 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 11391583 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9493121 — Surrogate Endpoint (SUR): Blood pressure
Study 24719046 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24719046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24719046 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23285043 — Surrogate Endpoint (SUR): Blood pressure
Study 20098295 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30572548 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 27206212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27206212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27206212 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8425237 — Surrogate Endpoint (SUR): Blood pressure
Study 2949584 — Surrogate Endpoint (SUR): Blood pressure
Study 15736108 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15736108 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9014745 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31322914 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25403211 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25403211 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 15097246 — Surrogate Endpoint (SUR): Blood pressure
Study 12234947 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9652433 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28740125 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28740125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29244111 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29244111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20530280 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16189633 — Surrogate Endpoint (SUR): Serum calcium
Study 16189633 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 10955749 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15999421 — Safety Biomarker (SAF): Hyaluronic acid
Study 12198664 — Monitoring Biomarker (MOI): HBV DNA
Study 25961767 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 24001627 — Surrogate Endpoint (SUR): Blood pressure
Study 15025555 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 11903420 — Surrogate Endpoint (SUR): Blood pressure
Study 11903420 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9577377 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 7944471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28840750 — Safety Biomarker (SAF): Hyaluronic acid
Study 2685958 — Surrogate Endpoint (SUR): Blood pressure
Study 2685958 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29277060 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 29277060 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2428885 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 27039845 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27039845 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27039845 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 27039845 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20644331 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 20644331 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9925837 — Surrogate Endpoint (SUR): Serum calcium
Study 2106735 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2106735 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25469673 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 12874818 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1443738 — Surrogate Endpoint (SUR): Blood pressure
Study 3001563 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 3001563 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30806083 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 25860002 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19858237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11534565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11534565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3396267 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 25908311 — Surrogate Endpoint (SUR): Bone mineral density
Study 8355436 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 28199464 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26224879 — Surrogate Endpoint (SUR): Total kidney volume
Study 6107932 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 30075569 — Surrogate Endpoint (SUR): Bone mineral density
Study 23782581 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25646296 — Surrogate Endpoint (SUR): Blood pressure
Study 1406395 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1406395 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 30172724 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30172724 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 10464834 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27444687 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12077767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12077767 — Safety Biomarker (SAF): Interleukin 1
Study 29103081 — Predictive Biomarker (PRD): PDE10A mRNA
Genes: PDE10A
Study 23803951 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21254911 — Surrogate Endpoint (SUR): Bone mineral density
Study 21254911 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21254911 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23691825 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 19486260 — Surrogate Endpoint (SUR): Blood pressure
Study 30554783 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 20561917 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 17605234 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 17605234 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10594528 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7491848 — Surrogate Endpoint (SUR): Blood pressure
Study 29475928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 19131173 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 16459721 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16459721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16459721 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8935444 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 4082879 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30932181 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 30172759 — Predictive Biomarker (PRD): TK1 mRNA
Genes: TK1
Study 26563287 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 22496085 — Safety Biomarker (SAF): Reactive oxygen species
Study 12235692 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19221759 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 19221759 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19221759 — Surrogate Endpoint (SUR): Blood pressure
Study 17056241 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28424258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14700552 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 14700552 — Surrogate Endpoint (SUR): Bone mineral density
Study 15025402 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 31667542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24487458 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 23457130 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23457130 — Surrogate Endpoint (SUR): Blood pressure
Study 15307697 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 18272916 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 18272916 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18272916 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12657408 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 1542853 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30673744 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25189856 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 7946898 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23559149 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 14675411 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28603135 — Predictive Biomarker (PRD): ABCD2 mRNA
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study 23095282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11988132 — Surrogate Endpoint (SUR): Bone mineral density
Study 9808143 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9808143 — Surrogate Endpoint (SUR): Serum calcium
Study 28075228 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 14576659 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28606184 — Surrogate Endpoint (SUR): Blood pressure
Study 18822903 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 18822903 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18822903 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9015908 — Surrogate Endpoint (SUR): Blood pressure
Study 6738365 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19055987 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 11300450 — Surrogate Endpoint (SUR): Blood pressure
Study 9278210 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18410888 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18410888 — Surrogate Endpoint (SUR): Blood pressure
Study 16190386 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 28283863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18480522 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12051399 — Surrogate Endpoint (SUR): Serum creatinine
Study 12051399 — Surrogate Endpoint (SUR): Blood pressure
Study 12051399 — Surrogate Endpoint (SUR): Serum sodium
Study 1706023 — Surrogate Endpoint (SUR): Blood pressure
Study 31556937 — Surrogate Endpoint (SUR): Blood pressure
Study 30024861 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24048909 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20158297 — Surrogate Endpoint (SUR): Blood pressure
Study 22118842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22118842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22118842 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22118842 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31815678 — Surrogate Endpoint (SUR): Blood pressure
Study 17664472 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17664472 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7865648 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31738351 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8436090 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26739253 — Surrogate Endpoint (SUR): Blood pressure
Study 17140611 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 10195630 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1734985 — Surrogate Endpoint (SUR): Blood pressure
Study 24085591 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14628252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14628252 — Surrogate Endpoint (SUR): Blood pressure
Study 10737282 — Surrogate Endpoint (SUR): Blood pressure
Study 10199756 — Surrogate Endpoint (SUR): Bone mineral density
Study 29884405 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 11641743 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 11641743 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7850531 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24708775 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23125943 — Surrogate Endpoint (SUR): Blood pressure
Study 16048482 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 16048482 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 16048482 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31838585 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28407999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21454244 — Surrogate Endpoint (SUR): Serum testosterone
Study 15210738 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 10450749 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 793849 — Surrogate Endpoint (SUR): Blood pressure
Study 793849 — Surrogate Endpoint (SUR): Serum potassium
Study 793849 — Surrogate Endpoint (SUR): Serum uric acid
Study 28068788 — Safety Biomarker (SAF): BDNF
Study 8543958 — Surrogate Endpoint (SUR): Blood pressure
Study 2472488 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 2472488 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 26602296 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 21823420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21823420 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23801357 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 1548516 — Safety Biomarker (SAF): 51Cr-EDTA
Study 7148735 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 28248887 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28248887 — Surrogate Endpoint (SUR): Blood pressure
Study 26546068 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 371903 — Surrogate Endpoint (SUR): Blood pressure
Study 18847329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17118687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31033362 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31033362 — Surrogate Endpoint (SUR): Serum uric acid
Study 31033362 — Surrogate Endpoint (SUR): Blood pressure
Study 18665163 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1667511 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 6406649 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26858433 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 12390715 — Surrogate Endpoint (SUR): Blood pressure
Study 9932994 — Surrogate Endpoint (SUR): Blood pressure
Study 25864745 — Safety Biomarker (SAF): Anti-thyroid autoantibody
Study 15298427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29209951 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 10661604 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2312764 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21211642 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 18032935 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2905341 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2905341 — Surrogate Endpoint (SUR): Blood pressure
Study 28234152 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC