TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17506593 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7672156 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 7672156 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24809408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20003492 — Surrogate Endpoint (SUR): Blood pressure
Study 20003492 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20003492 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20003492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20003492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15886447 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 10623052 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7875757 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23890573 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 22174434 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22174434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17502727 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 15478000 — Surrogate Endpoint (SUR): Bone mineral density
Study 22812594 — Surrogate Endpoint (SUR): Blood pressure
Study 21293087 — Surrogate Endpoint (SUR): Blood pressure
Study 12923410 — Surrogate Endpoint (SUR): Blood pressure
Study 30471072 — Surrogate Endpoint (SUR): Blood pressure
Study 23683800 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 20556817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20556817 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22787172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22787172 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22787172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22787172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17363355 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 15353020 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 9535583 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 9535583 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2605788 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31680496 — Surrogate Endpoint (SUR): Blood pressure
Study 31430032 — Surrogate Endpoint (SUR): Blood pressure
Study 15623461 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15623461 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7509894 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7509894 — Surrogate Endpoint (SUR): Blood pressure
Study 21563507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16472935 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29529161 — Surrogate Endpoint (SUR): Blood pressure
Study 25185430 — Surrogate Endpoint (SUR): Serum uric acid
Study 25185430 — Surrogate Endpoint (SUR): Serum calcium
Study 12439601 — Predictive Biomarker (PRD): GGH mRNA
Genes: GGH
Study 8012639 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2658040 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30782915 — Surrogate Endpoint (SUR): Blood pressure
Study 16424444 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 16424444 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 16424444 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16424444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9187989 — Surrogate Endpoint (SUR): Blood pressure
Study 18625896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29398571 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29398571 — Surrogate Endpoint (SUR): Blood pressure
Study 15205198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15205198 — Predictive Biomarker (PRD): TRPV2 mRNA
Genes: TRPV2; VRL
Study 7986470 — Surrogate Endpoint (SUR): Blood pressure
Study 7986470 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31992372 — Surrogate Endpoint (SUR): Blood pressure
Study 2151278 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2151278 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 29026385 — Surrogate Endpoint (SUR): Blood pressure
Study 16333854 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8786722 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2276384 — Surrogate Endpoint (SUR): Blood pressure
Study 22805324 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15567174 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15567174 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 15567174 — Predictive Biomarker (PRD): AGR2 mRNA
Genes: AGR2; AG2; UNQ515/PRO1030
Study 15567174 — Predictive Biomarker (PRD): Phospholipase A2 inhibitory protein
Genes: ANXA1; ANX1; LPC1
Study 10446819 — Surrogate Endpoint (SUR): Blood pressure
Study 10246462 — Surrogate Endpoint (SUR): Blood pressure
Study 1798005 — Surrogate Endpoint (SUR): Blood pressure
Study 6358278 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 31601583 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 27402064 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 25015689 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22230419 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19076192 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 9746115 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17364275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28091703 — Surrogate Endpoint (SUR): Blood pressure
Study 15189478 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15189478 — Surrogate Endpoint (SUR): Blood pressure
Study 9501680 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18218206 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21962261 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21962261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21962261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21962261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27578117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 338206 — Surrogate Endpoint (SUR): Serum testosterone
Study 22147649 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 31072180 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 31072180 — Monitoring Biomarker (MOI): Procalcitonin
Study 31072180 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31072180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17463075 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 15465747 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9551703 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 9551703 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9551703 — Surrogate Endpoint (SUR): Blood pressure
Study 7059257 — Surrogate Endpoint (SUR): Blood pressure
Study 24509134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24509134 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24509134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20378381 — Surrogate Endpoint (SUR): Bone mineral density
Study 10234600 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9193325 — Surrogate Endpoint (SUR): Bone mineral density
Study 24284272 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 15662234 — Surrogate Endpoint (SUR): Blood pressure
Study 15662234 — Safety Biomarker (SAF): Urinary microalbumin
Study 1835292 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1835292 — Surrogate Endpoint (SUR): Blood pressure
Study 31377160 — Predictive Biomarker (PRD): ESR1
Genes: NR3A1; Era; ER-alpha
Study 31377160 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31377160 — Predictive Biomarker (PRD): Hormone receptor
Study 21343393 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 9568453 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26690312 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 1877740 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 25251443 — Predictive Biomarker (PRD): SOX11 mRNA
Genes: SOX11
Study 25251443 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 25251443 — Predictive Biomarker (PRD): SMAD1 mRNA
Genes: SMAD1; BSP1; MADH1; MADR1
Study 25251443 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 25251443 — Predictive Biomarker (PRD): SMAD3 mRNA
Genes: SMAD3; MADH3
Study 25251443 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study 23353608 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9726802 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9726802 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2568072 — Surrogate Endpoint (SUR): Blood pressure
Study 21607703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19759043 — Surrogate Endpoint (SUR): Serum creatinine
Study 17726314 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17726314 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 17726314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7995386 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7995386 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 2457768 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2457768 — Surrogate Endpoint (SUR): Blood pressure
Study 17880017 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9794348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25430415 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9360208 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9360208 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20692140 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18797738 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 8622245 — Surrogate Endpoint (SUR): Blood pressure
Study 8622245 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8622245 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8622245 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30466402 — Surrogate Endpoint (SUR): Blood pressure
Study 22759406 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22490901 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22490901 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24748629 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23378102 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 19661449 — Surrogate Endpoint (SUR): Blood pressure
Study 10785875 — Surrogate Endpoint (SUR): Blood pressure
Study 29325799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11114683 — Surrogate Endpoint (SUR): Blood pressure
Study 28289041 — Surrogate Endpoint (SUR): Blood pressure
Study 23339731 — Surrogate Endpoint (SUR): Blood pressure
Study 19018783 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 14643577 — Surrogate Endpoint (SUR): Blood pressure
Study 31280343 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26819195 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26819195 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 21569370 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19236277 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16449396 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9184262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9184262 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30354330 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 30354330 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26630992 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 14604244 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9186303 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 9186303 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25725625 — Surrogate Endpoint (SUR): Blood pressure
Study 23551710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23551710 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 21775166 — Surrogate Endpoint (SUR): Blood pressure
Study 21775166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21775166 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10770306 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9293310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9293310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8223838 — Surrogate Endpoint (SUR): Blood pressure
Study 28697803 — Surrogate Endpoint (SUR): Blood pressure
Study 8932874 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8932874 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ESR1 mRNA
Genes: ESR1; ESR; NR3A1
Study 30788944 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18269820 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1722310 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 31426864 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 26334096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 20070721 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 17317391 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17317391 — Surrogate Endpoint (SUR): Blood pressure
Study 17317391 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9362390 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 1318845 — Surrogate Endpoint (SUR): Blood pressure
Study 1318845 — Surrogate Endpoint (SUR): Serum sodium
Study 1318845 — Surrogate Endpoint (SUR): Serum potassium
Study 18305461 — Predictive Biomarker (PRD): ADORA2A mRNA
Genes: ADORA2A; ADORA2
Study 18305461 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 3904394 — Surrogate Endpoint (SUR): Blood pressure
Study 25367242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18851750 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9190239 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1283426 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1283426 — Surrogate Endpoint (SUR): Serum creatinine
Study 28135975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28135975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28135975 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28135975 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19022694 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 15300183 — Surrogate Endpoint (SUR): Bone mineral density
Study 11372667 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 11372667 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19888533 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 19888533 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 30515674 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30515674 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23046593 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 12730532 — Surrogate Endpoint (SUR): Bone mineral density
Study 2833090 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2833090 — Surrogate Endpoint (SUR): Blood pressure
Study 2833090 — Surrogate Endpoint (SUR): Serum uric acid
Study 2833090 — Surrogate Endpoint (SUR): Serum potassium
Study 26335224 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 24005315 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 12750540 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 30998125 — Predictive Biomarker (PRD): FAU mRNA
Genes: FAU
Study 24152823 — Surrogate Endpoint (SUR): Blood pressure
Study 18341178 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28133925 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 19210151 — Surrogate Endpoint (SUR): Blood pressure
Study 20352546 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 30540568 — Safety Biomarker (SAF): DRD2
Study 27490915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18628422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29783024 — Surrogate Endpoint (SUR): Serum creatinine
Study 9704685 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28838379 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 21811833 — Surrogate Endpoint (SUR): Blood pressure
Study 17467954 — Surrogate Endpoint (SUR): Bone mineral density
Study 12482109 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12482109 — Surrogate Endpoint (SUR): Bone mineral density
Study 30668137 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 28138315 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23741991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23741991 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 23741991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23741991 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19172543 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 27021556 — Surrogate Endpoint (SUR): Blood pressure
Study 27021556 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27021556 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18443125 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 18443125 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 25987260 — Surrogate Endpoint (SUR): Serum creatinine
Study 24282774 — Surrogate Endpoint (SUR): Blood pressure
Study 15006009 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 22978405 — Surrogate Endpoint (SUR): Serum testosterone
Study 19192440 — Safety Biomarker (SAF): DRD2
Study 10698231 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8232766 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8232766 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 28161697 — Surrogate Endpoint (SUR): Blood pressure
Study 25850966 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 22721608 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22721608 — Surrogate Endpoint (SUR): Serum testosterone
Study 19167999 — Safety Biomarker (SAF): Reactive oxygen species
Study 16966852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31166987 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31166987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31166987 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26567961 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15987536 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9475275 — Surrogate Endpoint (SUR): Blood pressure
Study 19920000 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16753973 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9990360 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45