TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21930607 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 21930607 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22260988 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 12534644 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10987609 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 31758080 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 18948032 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 18948032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18948032 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15039493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7870226 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 24666765 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 19546583 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19546583 — Surrogate Endpoint (SUR): Blood pressure
Study 19546583 — Surrogate Endpoint (SUR): Serum potassium
Study 11798515 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 9093983 — Surrogate Endpoint (SUR): Serum calcium
Study 9093983 — Surrogate Endpoint (SUR): Serum sodium
Study 9093983 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 2282101 — Surrogate Endpoint (SUR): Blood pressure
Study 24021551 — Predictive Biomarker (PRD): GATA4 mRNA
Genes: GATA4
Study 24021551 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYH11 mRNA
Genes: MYH11; KIAA0866
Study 24021551 — Predictive Biomarker (PRD): GJA5 mRNA
Genes: GJA5
Study 23527300 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study 23527300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12921628 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 9088585 — Surrogate Endpoint (SUR): Blood pressure
Study 7655642 — Surrogate Endpoint (SUR): Bone mineral density
Study 24024839 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24024839 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24024839 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 1488321 — Predictive Biomarker (PRD): GLI2 mRNA
Genes: GLI2; THP
Study 1488321 — Surrogate Endpoint (SUR): Blood pressure
Study 27430558 — Surrogate Endpoint (SUR): Blood pressure
Study 18794430 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8775721 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 2901839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28689678 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25596004 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25596004 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8373876 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 8373876 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 24473387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24473387 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24473387 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17698336 — Surrogate Endpoint (SUR): Blood pressure
Study 10587413 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8692528 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15674004 — Surrogate Endpoint (SUR): Blood pressure
Study 25329433 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25329433 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25329433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9440763 — Surrogate Endpoint (SUR): Bone mineral density
Study 16461376 — Surrogate Endpoint (SUR): Blood pressure
Study 15876979 — Surrogate Endpoint (SUR): Blood pressure
Study 15733514 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30914102 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30914102 — Surrogate Endpoint (SUR): Blood pressure
Study 15121491 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3128767 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31891288 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 30638544 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 17317371 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15063607 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17143175 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17143175 — Surrogate Endpoint (SUR): Blood pressure
Study 11451721 — Surrogate Endpoint (SUR): Blood pressure
Study 8031555 — Surrogate Endpoint (SUR): Blood pressure
Study 8031555 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25651245 — Surrogate Endpoint (SUR): Serum creatinine
Study 18706705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30105362 — Surrogate Endpoint (SUR): Serum sodium
Study 25440377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25440377 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 25440377 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 18056193 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 1980981 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 1980981 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 25577782 — Surrogate Endpoint (SUR): Blood pressure
Study 19662337 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19662337 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8923090 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25062857 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 14703410 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8538479 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 8538479 — Surrogate Endpoint (SUR): Bone mineral density
Study 30419858 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26922296 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25324618 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 25324618 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 9622211 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9622211 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 7888287 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7888287 — Surrogate Endpoint (SUR): Plasma ammonia
Study 3352163 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 31857313 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28835380 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 28835380 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21306916 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19301201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19301201 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 11902819 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7680947 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31574544 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24235081 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24235081 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 27182021 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27182021 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24019207 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 24019207 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 24019207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19761935 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19761935 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 9290026 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2979110 — Surrogate Endpoint (SUR): Blood pressure
Study 26268636 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26268636 — Surrogate Endpoint (SUR): Blood pressure
Study 26268636 — Surrogate Endpoint (SUR): Serum uric acid
Study 20696083 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 20696083 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26211827 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21981269 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 20503800 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 7611862 — Safety Biomarker (SAF): Interleukin 1
Study 7611862 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7611862 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23888317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23888317 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23888317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23888317 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19238517 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 11600586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 8282330 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28978327 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 28978327 — Surrogate Endpoint (SUR): Serum testosterone
Study 23209276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9659350 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 766555 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29137111 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23250912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23250912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23250912 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16762939 — Surrogate Endpoint (SUR): Blood pressure
Study 18812447 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 17485597 — Surrogate Endpoint (SUR): Blood pressure
Study 26215480 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22966864 — Surrogate Endpoint (SUR): Blood pressure
Study 15876213 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 29852043 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23435861 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16716061 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16716061 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9215516 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9215516 — Surrogate Endpoint (SUR): Blood pressure
Study 9215516 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8267470 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 23735098 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 23735098 — Predictive Biomarker (PRD): SKAP2 mRNA
Genes: SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R
Study 16490490 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16490490 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study 16490490 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8405695 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28601864 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 28601864 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28601864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22992332 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 11225291 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11225291 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 3925217 — Surrogate Endpoint (SUR): Blood pressure
Study 10691226 — Surrogate Endpoint (SUR): Blood pressure
Study 24731671 — Predictive Biomarker (PRD): Hormone receptor
Study 24731671 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23332800 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 16427861 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 10697448 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29652169 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 15765628 — Surrogate Endpoint (SUR): Bone mineral density
Study 15765628 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7741138 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2297462 — Surrogate Endpoint (SUR): Blood pressure
Study 29065193 — Safety Biomarker (SAF): DRD3
Study 26765470 — Safety Biomarker (SAF): miR-22
Genes: MIR22
Study 26765470 — Safety Biomarker (SAF): miR-30a
Genes: MIR30A
Study 26765470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 24844551 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 24844551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16466011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16466011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23812762 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 31996311 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 31996311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23992602 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12792581 — Surrogate Endpoint (SUR): Blood pressure
Study 24845177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18728175 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18728175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14512127 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30639342 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 26636426 — Predictive Biomarker (PRD): RAB3D mRNA
Genes: RAB3D; GOV; RAB16
Study 22970177 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20233625 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 20233625 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 20233625 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 17341568 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21412266 — Surrogate Endpoint (SUR): Blood pressure
Study 17634896 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 372867 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28295451 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 28295451 — Predictive Biomarker (PRD): CCRL2 mRNA
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 17050012 — Surrogate Endpoint (SUR): Blood pressure
Study 2582838 — Surrogate Endpoint (SUR): Blood pressure
Study 26350603 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 23736006 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18506165 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11027880 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20585106 — Surrogate Endpoint (SUR): Blood pressure
Study 29338540 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 29338540 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 27023594 — Surrogate Endpoint (SUR): Blood pressure
Study 16571160 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 10639540 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31919989 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28843718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28843718 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11023502 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 11023502 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 2894973 — Surrogate Endpoint (SUR): Blood pressure
Study 20090366 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26830678 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26830678 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 22211091 — Surrogate Endpoint (SUR): Serum potassium
Study 20663207 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 15854388 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30563789 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28522637 — Surrogate Endpoint (SUR): Blood pressure
Study 23686372 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17708609 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 28652529 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 28652529 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28652529 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26039494 — Surrogate Endpoint (SUR): Blood pressure
Study 21747241 — Surrogate Endpoint (SUR): Blood pressure
Study 17101852 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11452243 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7924781 — Surrogate Endpoint (SUR): Blood pressure
Study 30032274 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30032274 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27216492 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17944983 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17944983 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 19656211 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19656211 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11463764 — Surrogate Endpoint (SUR): Blood pressure
Study 9722222 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28436727 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25758280 — Predictive Biomarker (PRD): CCN3 mRNA
Genes: CCN3; IGFBP9; NOV; NOVH
Study 14713182 — Surrogate Endpoint (SUR): Serum creatinine
Study 7572943 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30615666 — Surrogate Endpoint (SUR): Blood pressure
Study 23538154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21565557 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18795378 — Surrogate Endpoint (SUR): Serum calcium
Study 29025835 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 23160656 — Surrogate Endpoint (SUR): Blood pressure
Study 7981460 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7981460 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15513697 — Surrogate Endpoint (SUR): Serum sodium
Study 23742058 — Surrogate Endpoint (SUR): Blood pressure
Study 9228438 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3880686 — Surrogate Endpoint (SUR): Blood pressure
Study 3880686 — Surrogate Endpoint (SUR): Serum potassium
Study 19727956 — Monitoring Biomarker (MOI): HBV DNA
Study 10903217 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27138575 — Predictive Biomarker (PRD): Hormone receptor
Study 27138575 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24620850 — Surrogate Endpoint (SUR): Blood pressure
Study 3171790 — Surrogate Endpoint (SUR): Serum creatinine
Study 28419200 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17875958 — Surrogate Endpoint (SUR): Serum uric acid
Study 31979305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25624756 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18350737 — Surrogate Endpoint (SUR): Blood pressure
Study 18350737 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15361892 — Surrogate Endpoint (SUR): Blood pressure