TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17941871 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12813380 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 11263274 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 31783777 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 31783777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31783777 — Surrogate Endpoint (SUR): Blood pressure
Study 29187474 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 29187474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27721534 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10913921 — Surrogate Endpoint (SUR): Bone mineral density
Study 30756411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30756411 — Safety Biomarker (SAF): Hyaluronic acid
Study 26688003 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 18194413 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 15672001 — Surrogate Endpoint (SUR): Bone mineral density
Study 10822909 — Safety Biomarker (SAF): Reactive oxygen species
Study 24562349 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24562349 — Surrogate Endpoint (SUR): Blood pressure
Study 18611150 — Surrogate Endpoint (SUR): Blood pressure
Study 30932134 — Predictive Biomarker (PRD): SLC7A5 mRNA
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study 30932134 — Predictive Biomarker (PRD): CASTOR1 mRNA
Genes: CASTOR1; GATSL3
Study 30932134 — Predictive Biomarker (PRD): 40S ribosomal protein S6
Genes: RPS6; OK/SW-cl.2
Study 23413492 — Safety Biomarker (SAF): Hyaluronic acid
Study 26679879 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 14529880 — Surrogate Endpoint (SUR): Serum creatinine
Study 14529880 — Surrogate Endpoint (SUR): Blood pressure
Study 11092645 — Surrogate Endpoint (SUR): Blood pressure
Study 11092645 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27171844 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30880163 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29283224 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7621644 — Surrogate Endpoint (SUR): Blood pressure
Study 7621644 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31361307 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 31361307 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 23688096 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19901116 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19901116 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19901116 — Surrogate Endpoint (SUR): Blood pressure
Study 9459537 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27245786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19921347 — Predictive Biomarker (PRD): CD74 mRNA
Genes: CD74; DHLAG
Study 17092376 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 10100082 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10100082 — Surrogate Endpoint (SUR): Blood pressure
Study 31481039 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31481039 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28902880 — Surrogate Endpoint (SUR): Blood pressure
Study 27175681 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 24585267 — Surrogate Endpoint (SUR): Blood pressure
Study 16087825 — Surrogate Endpoint (SUR): Bone mineral density
Study 26576619 — Surrogate Endpoint (SUR): Serum potassium
Study 25553599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25553599 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 14498755 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14498755 — Surrogate Endpoint (SUR): Blood pressure
Study 3898701 — Surrogate Endpoint (SUR): Blood pressure
Study 30255760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30255760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30255760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16109319 — Surrogate Endpoint (SUR): Blood pressure
Study 7739944 — Surrogate Endpoint (SUR): Blood pressure
Study 1675042 — Surrogate Endpoint (SUR): Blood pressure
Study 31363328 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23562192 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19351943 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15319494 — Surrogate Endpoint (SUR): Bone mineral density
Study 9406807 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 25406227 — Surrogate Endpoint (SUR): Serum sodium
Study 19000095 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19000095 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 10510144 — Surrogate Endpoint (SUR): Blood pressure
Study 6790048 — Surrogate Endpoint (SUR): Blood pressure
Study 26084792 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26084792 — Surrogate Endpoint (SUR): Blood pressure
Study 22194326 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 2285628 — Surrogate Endpoint (SUR): Blood pressure
Study 31996940 — Surrogate Endpoint (SUR): Blood pressure
Study 28135841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28135841 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28135841 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8554003 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1886589 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1886589 — Surrogate Endpoint (SUR): Blood pressure
Study 15264735 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31391223 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27708251 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 27708251 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 27708251 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27708251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21536983 — Surrogate Endpoint (SUR): Blood pressure
Study 11590875 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9125088 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 2979237 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29878856 — Safety Biomarker (SAF): Hyaluronic acid
Study 18356180 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18356180 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18356180 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 9504729 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9504729 — Surrogate Endpoint (SUR): Blood pressure
Study 26444473 — Surrogate Endpoint (SUR): Blood pressure
Study 12665164 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 22955513 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2202231 — Surrogate Endpoint (SUR): Blood pressure
Study 7040496 — Surrogate Endpoint (SUR): Blood pressure
Study 7040496 — Surrogate Endpoint (SUR): Serum sodium
Study 15467498 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7534847 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31754703 — Predictive Biomarker (PRD): SLCO3A1 mRNA
Genes: SLCO3A1; OATP3A1; OATPD; SLC21A11
Study 31754703 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 31754703 — Predictive Biomarker (PRD): NR1I2 mRNA
Genes: NR1I2; PXR
Study 31754703 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 31754703 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31754703 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 31754703 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 19861543 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 16518959 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11506518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11506518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9407455 — Surrogate Endpoint (SUR): Serum creatinine
Study 19110359 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19110359 — Surrogate Endpoint (SUR): Serum calcium
Study 11585352 — Surrogate Endpoint (SUR): Bone mineral density
Study 10447226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10447226 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10447226 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29725824 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25123295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22376210 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17495015 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 2478330 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11171896 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 29970404 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 24618231 — Surrogate Endpoint (SUR): Blood pressure
Study 18192950 — Surrogate Endpoint (SUR): Blood pressure
Study 11669169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24951103 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19117833 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19117833 — Surrogate Endpoint (SUR): Serum calcium
Study 17674917 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 14724665 — Surrogate Endpoint (SUR): Blood pressure
Study 8314960 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28703491 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 28703491 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20184578 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12864879 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2945783 — Surrogate Endpoint (SUR): Blood pressure
Study 29415668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29415668 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19671203 — Surrogate Endpoint (SUR): Blood pressure
Study 7925877 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 7925877 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31166599 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31166599 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23256446 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23256446 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 23256446 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23256446 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18316155 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 18316155 — Surrogate Endpoint (SUR): Blood pressure
Study 9783766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2455840 — Surrogate Endpoint (SUR): Blood pressure
Study 25514106 — Surrogate Endpoint (SUR): Bone mineral density
Study 23466048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8238221 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8238221 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11563407 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1920340 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1920340 — Surrogate Endpoint (SUR): Blood pressure
Study 31792485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31792485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31792485 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 31792485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24965797 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 28407662 — Surrogate Endpoint (SUR): Blood pressure
Study 8279841 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27437883 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24925464 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 1514169 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15830180 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 24379010 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 21564156 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 2851762 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 30428290 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9105568 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 31977921 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 27262419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27262419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2110199 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22571226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 17473196 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 18848786 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18786729 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 15800138 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31982039 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 31982039 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 23150980 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17942609 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12858441 — Surrogate Endpoint (SUR): Bone mineral density
Study 1859518 — Surrogate Endpoint (SUR): Blood pressure
Study 31504594 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24332218 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 15711245 — Surrogate Endpoint (SUR): Serum creatinine
Study 2523548 — Surrogate Endpoint (SUR): Blood pressure
Study 1071693 — Surrogate Endpoint (SUR): Blood pressure
Study 16960176 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 15055228 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25471305 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study 25471305 — Predictive Biomarker (PRD): SIRPB1 mRNA
Genes: SIRPB1
Study 25471305 — Safety Biomarker (SAF): Amphiregulin
Genes: AREG; AREGB; SDGF
Study 25471305 — Predictive Biomarker (PRD): TNFAIP3 mRNA
Genes: TNFAIP3; OTUD7C
Study 10555884 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10555884 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10555884 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 10555884 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 1974748 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1974748 — Surrogate Endpoint (SUR): Blood pressure
Study 31785551 — Surrogate Endpoint (SUR): Blood pressure
Study 25058107 — Surrogate Endpoint (SUR): Bone mineral density
Study 17356969 — Surrogate Endpoint (SUR): Bone mineral density
Study 30691766 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 28408697 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 28408697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18422779 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study 16195134 — Surrogate Endpoint (SUR): Blood pressure
Study 22915637 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 22915637 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 18444532 — Surrogate Endpoint (SUR): Blood pressure
Study 10999062 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10999062 — Surrogate Endpoint (SUR): Blood pressure
Study 22149452 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22149452 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31179485 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28197938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28197938 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29231407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22459966 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 30569673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26538525 — Surrogate Endpoint (SUR): Bone mineral density
Study 20163368 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 10793877 — Surrogate Endpoint (SUR): Bone mineral density
Study 29687898 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28343401 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9443096 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 31615291 — Surrogate Endpoint (SUR): Blood pressure
Study 11293552 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11293552 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11293552 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27539149 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 26288392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23220158 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10718389 — Surrogate Endpoint (SUR): Blood pressure
Study 1680813 — Surrogate Endpoint (SUR): Blood pressure
Study 18357917 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18357917 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 18357917 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 30664702 — Surrogate Endpoint (SUR): Blood pressure
Study 20308663 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9084524 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9084524 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 9084524 — Surrogate Endpoint (SUR): Blood pressure
Study 9648963 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 2478779 — Surrogate Endpoint (SUR): Blood pressure
Study 28625637 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study 25924819 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23949918 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 18650507 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 18650507 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 8790926 — Surrogate Endpoint (SUR): Blood pressure
Study 8790926 — Surrogate Endpoint (SUR): Serum creatinine
Study 1729864 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29974521 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 20198491 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study 10696854 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15753414 — Surrogate Endpoint (SUR): Bone mineral density
Study 29737412 — Surrogate Endpoint (SUR): Bone mineral density
Study 24333554 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 24333554 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23091128 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19114683 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30545409 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 26791805 — Surrogate Endpoint (SUR): Serum testosterone
Study 24257810 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 28170391 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 21616170 — Surrogate Endpoint (SUR): Blood pressure
Study 25830947 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1