TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29799329 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29799329 — Predictive Biomarker (PRD): Hormone receptor
Study 29800181 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 29801465 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29802952 — Surrogate Endpoint (SUR): Blood pressure
Study 29804060 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 29804905 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29805324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29807287 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29807396 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29807781 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 29808092 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29808092 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 29812997 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 29812996 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 29843711 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29843711 — Surrogate Endpoint (SUR): Serum creatinine
Study 29843792 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29843792 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29844096 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 29844102 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study 29846328 — Surrogate Endpoint (SUR): Blood pressure
Study 29848736 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29849841 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29850244 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 29851546 — Safety Biomarker (SAF): Interleukin 12
Study 29853658 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29853658 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29855806 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29856132 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29856824 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29857145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29858106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 29858547 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29858547 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29858547 — Predictive Biomarker (PRD): IL13RA1 mRNA
Genes: IL13RA1; IL13R; IL13RA
Study 29858547 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 29858547 — Predictive Biomarker (PRD): OSMR mRNA
Genes: OSMR; OSMRB
Study 29859851 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 29860039 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 29860039 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 29860039 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 29860938 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 29861796 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 29862011 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 29862437 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 29862437 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29864044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29865778 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 29867728 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29867728 — Surrogate Endpoint (SUR): Blood pressure
Study 29867923 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29867922 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29867922 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29867922 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study 29868473 — Predictive Biomarker (PRD): NR2E3 mRNA
Genes: NR2E3; PNR; RNR
Study 29869534 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 29874098 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29874546 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29874546 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29875139 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 29876358 — Surrogate Endpoint (SUR): Blood pressure
Study 29876839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29878866 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 29879283 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29880009 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 29880308 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study 29882017 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 29884223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29885989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29885989 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29885989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29886024 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 29886425 — Surrogate Endpoint (SUR): Blood pressure
Study 29886724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 29888205 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29888205 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 29890123 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 29890123 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 29890123 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29890128 — Predictive Biomarker (PRD): THY1 mRNA
Genes: THY1
Study 29890128 — Predictive Biomarker (PRD): ADAM12 mRNA
Genes: ADAM12; MLTN; UNQ346/PRO545
Study 29891238 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 29891853 — Predictive Biomarker (PRD): VAV3 mRNA
Genes: VAV3
Study 29891853 — Predictive Biomarker (PRD): ZNF682 mRNA
Genes: ZNF682
Study 29892208 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 29895668 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29895668 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29896154 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 29896154 — Safety Biomarker (SAF): DRD2
Study 29896479 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29896479 — Safety Biomarker (SAF): BDNF
Study 29897486 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29897841 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 29898218 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29898218 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29898762 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29898762 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29898765 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29898765 — Surrogate Endpoint (SUR): Blood pressure
Study 29898822 — Surrogate Endpoint (SUR): Blood pressure
Study 29898959 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 29898959 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 29899062 — Predictive Biomarker (PRD): NGFR mRNA
Genes: NGFR; TNFRSF16
Study 29899820 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 29901610 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 29901700 — Predictive Biomarker (PRD): APOA2 mRNA
Genes: APOA2
Study 29901727 — Predictive Biomarker (PRD): CDO1 mRNA
Genes: CDO1
Study 29901727 — Predictive Biomarker (PRD): BCKDHA mRNA
Genes: BCKDHA
Study 29901727 — Predictive Biomarker (PRD): BCAT1 mRNA
Genes: BCAT1; BCT1; ECA39
Study 29902988 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 29903707 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 29903793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29903860 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 29903860 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29905488 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 29907093 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 29909069 — Predictive Biomarker (PRD): DHODH mRNA
Genes: DHODH
Study 29909101 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29912343 — Surrogate Endpoint (SUR): Sperm parameters
Study 29912813 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 29912924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29912924 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29914544 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29914960 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 29915522 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 29915941 — Safety Biomarker (SAF): Human leucocyte antigen
Study 29916861 — Surrogate Endpoint (SUR): Blood pressure
Study 29920582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29920582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29920584 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29921512 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29922574 — Predictive Biomarker (PRD): ATXN1 mRNA
Genes: ATXN1; ATX1; SCA1
Study 29922574 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 29922574 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 29923092 — Predictive Biomarker (PRD): CLN3 mRNA
Genes: CLN3; BTS
Study 29925376 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 29925376 — Predictive Biomarker (PRD): DUSP1 mRNA
Genes: DUSP1; CL100; MKP1; PTPN10; VH1
Study 29925376 — Predictive Biomarker (PRD): PPP1R15A mRNA
Genes: PPP1R15A; GADD34
Study 29925433 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29925497 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 29925497 — Predictive Biomarker (PRD): ARL2BP mRNA
Genes: ARL2BP; BART; BART1
Study 29925499 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 29925499 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29925913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29925913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29926156 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29929092 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 29929491 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 29929514 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 29931453 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29931812 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29933096 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 29933096 — Surrogate Endpoint (SUR): Bone mineral density
Study 29933761 — Surrogate Endpoint (SUR): Pathological complete response
Study 29933912 — Monitoring Biomarker (MOI): Cell-free DNA
Study 29934438 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 29934438 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 29934438 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 29934438 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 29934438 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 29935810 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 29936086 — Surrogate Endpoint (SUR): Blood pressure
Study 29936438 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 29936438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29936438 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 29936438 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 29937300 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 29937300 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 29938395 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29938395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 29938395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 29938395 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 29940870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29940870 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29940870 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29941024 — Predictive Biomarker (PRD): LIPE mRNA
Genes: LIPE
Study 29941458 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29941458 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29941469 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 29942123 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29942123 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29942666 — Predictive Biomarker (PRD): Microsatellite instability
Study 29944678 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29945631 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 29945738 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29946683 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29946946 — Surrogate Endpoint (SUR): Blood pressure
Study 29948106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29948286 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29948766 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29948766 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 29949718 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 29950465 — Predictive Biomarker (PRD): DCLRE1C mRNA
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study 29951599 — Surrogate Endpoint (SUR): Serum calcium
Study 29954415 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 29954415 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 29955381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29955695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29955792 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29955793 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 29955793 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 29958223 — Surrogate Endpoint (SUR): Blood pressure
Study 29958797 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 29958797 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 29959809 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29960116 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29960116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29960588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29962926 — Surrogate Endpoint (SUR): Blood pressure
Study 29963053 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 29966429 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29966800 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29968431 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29968437 — Surrogate Endpoint (SUR): Blood pressure
Study 29969998 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 29970005 — Surrogate Endpoint (SUR): Serum creatinine
Study 29970108 — Predictive Biomarker (PRD): RYR1 mRNA
Genes: RYR1; RYDR
Study 29970357 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 29970389 — Safety Biomarker (SAF): Hyaluronic acid
Study 29972716 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29973153 — Predictive Biomarker (PRD): PPP1R15A mRNA
Genes: PPP1R15A; GADD34
Study 29973153 — Predictive Biomarker (PRD): DEFB1 mRNA
Genes: DEFB1; BD1; HBD1
Study 29973153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29973153 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 29973153 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 29973204 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 29973204 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29973204 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 29973204 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 29973233 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 29974390 — Surrogate Endpoint (SUR): Bone mineral density
Study 29976218 — Predictive Biomarker (PRD): IDUA mRNA
Genes: IDUA
Study 29976503 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 29976503 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29977284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 29978216 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 29979092 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 29980535 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29980537 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29980544 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 29980572 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 29980572 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 29980655 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 29980655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29980894 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29980894 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29981205 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29981298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29981848 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29983355 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 29985747 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29985747 — Predictive Biomarker (PRD): PDHX mRNA
Genes: PDHX; PDX1
Study 29985987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29985987 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29985987 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 29986852 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29988503 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 29989854 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29992019 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29992019 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 29992039 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29992557 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29992557 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29992557 — Predictive Biomarker (PRD): Hormone receptor
Study 29996726 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11