TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01500070 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00330785 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01431157 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01263522 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00983294 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02646098 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01930188 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00001255 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT00001255 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00971555 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02383797 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00869609 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01497184 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06448000 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT01020435 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00952640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01634295 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03490500 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT00909519 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00696241 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03241810 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study NCT03241810 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03241810 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02356874 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02237937 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT00632905 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00632905 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01794689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01109277 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT01109277 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT00437957 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00437957 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT01274507 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT01252537 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02954783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02954783 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01211015 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT02214914 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT01098292 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT00853957 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02551705 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00937807 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03814226 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT04093115 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT00089609 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT01366976 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04540926 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02132039 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02338999 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT02338999 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01247077 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT03783936 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00407706 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT01817491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03746015 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01714908 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01714908 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00567606 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02998840 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02335203 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02335203 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT04150965 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study NCT00661622 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00061009 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00061009 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00813709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00624377 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00275314 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00195819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02331966 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study NCT02331966 — Predictive Biomarker (PRD): MAPK1 mRNA
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study NCT02331966 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02331966 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT02331966 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study NCT02331966 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study NCT02331966 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study NCT02331966 — Predictive Biomarker (PRD): AKT2 mRNA
Genes: AKT2
Study NCT02331966 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT02331966 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02331966 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT02331966 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02331966 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study NCT00436488 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT00992745 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT01554332 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT01246609 — Surrogate Endpoint (SUR): Serum sodium
Study NCT04410445 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01997866 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00722865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00722865 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01365546 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03366571 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT03366571 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02991118 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02845609 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study NCT02845609 — Safety Biomarker (SAF): N-acetylneuraminic acid
Study NCT03021616 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03137849 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03610685 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT03340922 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study NCT01403922 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01403922 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00004085 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02790788 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01072071 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00655785 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00655785 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00655785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT02919059 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02399072 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02790645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02790645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01622140 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03326037 — Predictive Biomarker (PRD): NPHS2 mRNA
Genes: NPHS2
Study NCT00788606 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02868983 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01542502 — Safety Biomarker (SAF): Interleukin 1
Study NCT02009865 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04453930 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03602807 — Safety Biomarker (SAF): 51Cr-EDTA
Study NCT00704548 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03112005 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02169609 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02169609 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01682928 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02978066 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04475406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04475406 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT04475406 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT00001628 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01218048 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03262714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03262714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02685111 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03311802 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02663297 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT04191863 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02820506 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT03867656 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01502241 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00091676 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03686345 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT03686345 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01109979 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01114685 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00417885 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04249440 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00060502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02782260 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT00457314 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT00185692 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03577054 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study NCT04617847 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00461188 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study NCT02083146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00899821 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00899821 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00899821 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study NCT00899821 — Safety Biomarker (SAF): Interleukin 12
Study NCT04480957 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01448928 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03602573 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03602573 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03602573 — Monitoring Biomarker (MOI): HCV DNA
Study NCT06463626 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06463626 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06463626 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03140475 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study NCT03137732 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT02637089 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02637089 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study NCT02637089 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02637089 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04309578 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01184105 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study NCT00006079 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT02488733 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT02834559 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02072330 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00703989 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02557451 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00004080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT03938792 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02078999 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02078999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00925548 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01737398 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT01737398 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT01190124 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03493282 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study NCT01525459 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02008214 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT00824057 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00824057 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01236898 — Safety Biomarker (SAF): N-acetylneuraminic acid
Study NCT00126620 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03441464 — Predictive Biomarker (PRD): LUM mRNA
Genes: LUM; LDC; SLRR2D
Study NCT01727076 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study NCT01219400 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02124304 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05062226 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study NCT03129009 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03129009 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00870168 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00289952 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00289952 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT01266837 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02536534 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00274287 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04964037 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT03424187 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03662841 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04930263 — Safety Biomarker (SAF): BDNF
Study NCT01775878 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02961283 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02961283 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02961283 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03008785 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01292005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02203513 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02203513 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT01434732 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00455715 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT04284306 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04284306 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00637663 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01644604 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01123200 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03143036 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT03270098 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00990314 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03517332 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01848132 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT01035177 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01635049 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT02973035 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03188484 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study NCT03506802 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05081778 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT01729793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01729793 — Safety Biomarker (SAF): Interleukin 1
Study NCT01729793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01729793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04565873 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00016042 — Safety Biomarker (SAF): Interleukin 12
Study NCT03720249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01851694 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01851694 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00734253 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03093532 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02162823 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT00000497 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01613703 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT04506372 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03039322 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT04931498 — Predictive Biomarker (PRD): SWAP70 mRNA
Genes: SWAP70; KIAA0640; HSPC321
Study NCT04931498 — Predictive Biomarker (PRD): GMPR mRNA
Genes: GMPR; GMPR1
Study NCT02899533 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT02899533 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04645303 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01788202 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05843526 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study NCT00045201 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00045201 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01224574 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00907959 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00907959 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02043652 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT00728013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04391439 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04391439 — Surrogate Endpoint (SUR): Serum potassium
Study NCT03757767 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT04414319 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02953249 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03979352 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT01414192 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00484406 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study NCT01310686 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF