TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20496732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20496732 — Safety Biomarker (SAF): Interleukin 1
Study 20496732 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 20496732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12218722 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28306329 — Surrogate Endpoint (SUR): Blood pressure
Study 25319752 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 12687466 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22967105 — Monitoring Biomarker (MOI): HBV DNA
Study 19005477 — Surrogate Endpoint (SUR): Blood pressure
Study 17289891 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27325226 — Surrogate Endpoint (SUR): Blood pressure
Study 804914 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 30796109 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 3815266 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 4077235 — Surrogate Endpoint (SUR): Blood pressure
Study 4077235 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 4077235 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30016983 — Safety Biomarker (SAF): Urinary microalbumin
Study 17634487 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 10517273 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 8730115 — Surrogate Endpoint (SUR): Bone mineral density
Study 1862156 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26408420 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26408420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26408420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26408420 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 26408420 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10481500 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7116662 — Surrogate Endpoint (SUR): Blood pressure
Study 7116662 — Surrogate Endpoint (SUR): Serum uric acid
Study 7116662 — Surrogate Endpoint (SUR): Serum potassium
Study 29147968 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 29147968 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 24879975 — Surrogate Endpoint (SUR): Blood pressure
Study 23859257 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 1345218 — Surrogate Endpoint (SUR): Blood pressure
Study 29414827 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7595716 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 728485 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 728485 — Predictive Biomarker (PRD): LUM mRNA
Genes: LUM; LDC; SLRR2D
Study 27346437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11130523 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11130523 — Surrogate Endpoint (SUR): Blood pressure
Study 30019249 — Surrogate Endpoint (SUR): Bone mineral density
Study 29099521 — Surrogate Endpoint (SUR): Blood pressure
Study 29099521 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9833848 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2633019 — Surrogate Endpoint (SUR): Blood pressure
Study 25375836 — Surrogate Endpoint (SUR): Blood pressure
Study 16883264 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8214491 — Surrogate Endpoint (SUR): Blood pressure
Study 25026287 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 6832623 — Surrogate Endpoint (SUR): Blood pressure
Study 30207587 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16728451 — Surrogate Endpoint (SUR): Blood pressure
Study 8834657 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 29863586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29863586 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 22571394 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22571394 — Surrogate Endpoint (SUR): Blood pressure
Study 19875481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10582974 — Surrogate Endpoint (SUR): Blood pressure
Study 30389952 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 21385196 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study 21385196 — Predictive Biomarker (PRD): LTA4H mRNA
Genes: LTA4H; LTA4
Study 20370845 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 231374 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26008855 — Surrogate Endpoint (SUR): Blood pressure
Study 21725873 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21725873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21725873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21725873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21725873 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21725873 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 4079660 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30204698 — Surrogate Endpoint (SUR): Blood pressure
Study 17004259 — Surrogate Endpoint (SUR): Serum creatinine
Study 20798154 — Surrogate Endpoint (SUR): Blood pressure
Study 19057270 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30135032 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 24801511 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 18322633 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12438293 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 29068756 — Surrogate Endpoint (SUR): Bone mineral density
Study 15801332 — Safety Biomarker (SAF): Interleukin 1
Study 8579082 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24091128 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24091128 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21846852 — Surrogate Endpoint (SUR): Serum uric acid
Study 11738123 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11738123 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9740604 — Surrogate Endpoint (SUR): Blood pressure
Study 8147338 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25424929 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22456294 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10573067 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27309266 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 2744731 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21447470 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 15274665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9428580 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9428580 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23213055 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 23213055 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21982456 — Surrogate Endpoint (SUR): Blood pressure
Study 16525857 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11359657 — Safety Biomarker (SAF): Interleukin 12
Study 25573021 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 19709658 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19709658 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 19709658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21871056 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 10705173 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10705173 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31531949 — Surrogate Endpoint (SUR): Serum uric acid
Study 25200587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8970416 — Surrogate Endpoint (SUR): Blood pressure
Study 1597846 — Surrogate Endpoint (SUR): Blood pressure
Study 19716142 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19716142 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 12826696 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 20011859 — Surrogate Endpoint (SUR): Blood pressure
Study 17257460 — Surrogate Endpoint (SUR): Blood pressure
Study 10840295 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26876722 — Surrogate Endpoint (SUR): Blood pressure
Study 10069869 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 10069869 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28872734 — Surrogate Endpoint (SUR): Blood pressure
Study 26197184 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 21368590 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21368590 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 3058133 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23549993 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17207378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17207378 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 14586044 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30400924 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26967321 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19539384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 8129130 — Surrogate Endpoint (SUR): Blood pressure
Study 31002110 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 25771840 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26510186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23413042 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 31642066 — Predictive Biomarker (PRD): FOXM1 mRNA
Genes: FOXM1; FKHL16; HFH11; MPP2; WIN
Study 6615674 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 23298885 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16870008 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23225445 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 23225445 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20664964 — Predictive Biomarker (PRD): ANXA10 mRNA
Genes: ANXA10; ANX14
Study 16301236 — Surrogate Endpoint (SUR): Blood pressure
Study 2719894 — Surrogate Endpoint (SUR): Blood pressure
Study 2719894 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 31213783 — Surrogate Endpoint (SUR): Bone mineral density
Study 26408274 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26408274 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23237136 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 11521725 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9220306 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30634208 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study 30634208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30634208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30634208 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30634208 — Safety Biomarker (SAF): Reactive oxygen species
Study 22508307 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 7669486 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7669486 — Safety Biomarker (SAF): DRD2
Study 25968008 — Surrogate Endpoint (SUR): Bone mineral density
Study 27114593 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 20215968 — Predictive Biomarker (PRD): KIF6 mRNA
Genes: KIF6; C6orf102
Study 11502788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11502788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9009974 — Surrogate Endpoint (SUR): Blood pressure
Study 9009974 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8518245 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8518245 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25277347 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 23537965 — Surrogate Endpoint (SUR): Blood pressure
Study 24931003 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24931003 — Surrogate Endpoint (SUR): Blood pressure
Study 24931003 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 22196062 — Predictive Biomarker (PRD): ARX mRNA
Genes: ARX
Study 22196062 — Surrogate Endpoint (SUR): Blood pressure
Study 27753600 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 29676980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 10463516 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26651393 — Predictive Biomarker (PRD): CHRNA7 mRNA
Genes: CHRNA7; NACHRA7
Study 15721840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15721840 — Predictive Biomarker (PRD): IL6ST mRNA
Genes: IL6ST
Study 10859864 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8517428 — Surrogate Endpoint (SUR): Blood pressure
Study 2872814 — Surrogate Endpoint (SUR): Blood pressure
Study 29713249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29713249 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 26959502 — Surrogate Endpoint (SUR): Blood pressure
Study 26959502 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7611868 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22796450 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20075532 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17353246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25067790 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25067790 — Surrogate Endpoint (SUR): Blood pressure
Study 12496548 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12496548 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8203837 — Predictive Biomarker (PRD): SPX mRNA
Genes: SPX; C12orf39
Study 27112637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21828036 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7852514 — Surrogate Endpoint (SUR): Serum calcium
Study 31877119 — Surrogate Endpoint (SUR): Blood pressure
Study 31095946 — Predictive Biomarker (PRD): HADHA mRNA
Genes: HADHA; HADH
Study 17620777 — Safety Biomarker (SAF): Hyaluronic acid
Study 9855027 — Surrogate Endpoint (SUR): Blood pressure
Study 7039841 — Surrogate Endpoint (SUR): Blood pressure
Study 25355268 — Surrogate Endpoint (SUR): Blood pressure
Study 25355268 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25355268 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16020773 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18083472 — Predictive Biomarker (PRD): UCN3 mRNA
Genes: UCN3; SPC
Study 12004273 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12004273 — Safety Biomarker (SAF): Interleukin 12
Study 8593380 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 25404229 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25012726 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 25012726 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 21816128 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 20095330 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 20095330 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24529119 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24529119 — Surrogate Endpoint (SUR): Blood pressure
Study 861131 — Surrogate Endpoint (SUR): Blood pressure
Study 27782964 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11607883 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 29424957 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study 23279632 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23279632 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30923521 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 30923521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27026335 — Surrogate Endpoint (SUR): Bone mineral density
Study 11904108 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11904108 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31845228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25820625 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 10446033 — Surrogate Endpoint (SUR): Blood pressure
Study 28633819 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28633819 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 30685114 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 28914978 — Predictive Biomarker (PRD): GSTZ1 mRNA
Genes: GSTZ1; MAAI
Study 22152230 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 22152230 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 20409019 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20409019 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 20409019 — Surrogate Endpoint (SUR): Blood pressure
Study 16275869 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16275869 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16275869 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 11929645 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16424233 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 6188892 — Surrogate Endpoint (SUR): Blood pressure
Study 20797314 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15856079 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 9531230 — Surrogate Endpoint (SUR): Bone mineral density
Study 8237801 — Surrogate Endpoint (SUR): Blood pressure
Study 8237801 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8237801 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19105585 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19105585 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 12802750 — Monitoring Biomarker (MOI): HBV DNA
Study 1386490 — Surrogate Endpoint (SUR): Blood pressure
Study 24632753 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17129904 — Predictive Biomarker (PRD): TNFSF14 mRNA
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study 1552197 — Surrogate Endpoint (SUR): Serum creatinine
Study 26746195 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26746195 — Surrogate Endpoint (SUR): Blood pressure
Study 18423809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14696681 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8468440 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 29702246 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25436051 — Surrogate Endpoint (SUR): Blood pressure
Study 12145058 — Surrogate Endpoint (SUR): Blood pressure
Study 6817770 — Surrogate Endpoint (SUR): Blood pressure
Study 30335131 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 16325036 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16325036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30500142 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 14557446 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 14557446 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14557446 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11783156 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 11783156 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11783156 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28808791 — Surrogate Endpoint (SUR): Blood pressure
Study 28808791 — Surrogate Endpoint (SUR): Serum creatinine