TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8704426 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 8704426 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22517646 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22517646 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 22517646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16391376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16391376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9057565 — Surrogate Endpoint (SUR): Serum creatinine
Study 15988707 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 28143867 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28143867 — Predictive Biomarker (PRD): Hormone receptor
Study 27506549 — Monitoring Biomarker (MOI): HBV DNA
Study 15117041 — Surrogate Endpoint (SUR): Serum potassium
Study 22827974 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 20346518 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 20346518 — Safety Biomarker (SAF): BDNF
Study 18656769 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12544629 — Surrogate Endpoint (SUR): Bone mineral density
Study 22132997 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15911190 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1986440 — Surrogate Endpoint (SUR): Blood pressure
Study 6833040 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6833040 — Surrogate Endpoint (SUR): Blood pressure
Study 28577938 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25761743 — Safety Biomarker (SAF): Hyaluronic acid
Study 24107284 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24107284 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24107284 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12712784 — Surrogate Endpoint (SUR): Blood pressure
Study 10714624 — Surrogate Endpoint (SUR): Serum calcium
Study 27242220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21594234 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21594234 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20658810 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 15088991 — Surrogate Endpoint (SUR): Bone mineral density
Study 7978470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7978470 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31058797 — Surrogate Endpoint (SUR): Blood pressure
Study 25196993 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 25196993 — Surrogate Endpoint (SUR): Bone mineral density
Study 21273183 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21273183 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 16896884 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11756857 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 9008458 — Surrogate Endpoint (SUR): Blood pressure
Study 29860040 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 24214881 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21967019 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21033613 — Surrogate Endpoint (SUR): Serum testosterone
Study 8913958 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30075678 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 11600822 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8045951 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17082468 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9762656 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9762656 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1695 — Surrogate Endpoint (SUR): Blood pressure
Study 10717600 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7482430 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7023672 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 7023672 — Surrogate Endpoint (SUR): Blood pressure
Study 30815684 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30815684 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 30815684 — Safety Biomarker (SAF): Protein AMBP
Genes: AMBP; HCP; ITIL
Study 30815684 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 24795252 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22176941 — Surrogate Endpoint (SUR): Blood pressure
Study 16988993 — Surrogate Endpoint (SUR): Blood pressure
Study 16039210 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16039210 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12015434 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 12015434 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 12015434 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 31884854 — Surrogate Endpoint (SUR): Blood pressure
Study 31884854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12083533 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 9725552 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2528256 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27436788 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22016505 — Surrogate Endpoint (SUR): Blood pressure
Study 27798024 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 24517156 — Surrogate Endpoint (SUR): Bone mineral density
Study 9314448 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31273513 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 31273513 — Predictive Biomarker (PRD): ZAP70 mRNA
Genes: ZAP70; SRK
Study 31273513 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 28271382 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19033020 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 10875609 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 10875609 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10875609 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10875609 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12139118 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1089522 — Surrogate Endpoint (SUR): Blood pressure
Study 27721013 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 27363424 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 31353666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26666876 — Surrogate Endpoint (SUR): Blood pressure
Study 26666876 — Safety Biomarker (SAF): Interleukin 1
Study 26666876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26666876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18785581 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25223728 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 11873074 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31033162 — Safety Biomarker (SAF): Hyaluronic acid
Study 30028657 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12468561 — Surrogate Endpoint (SUR): Blood pressure
Study 21816845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7881704 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7881704 — Surrogate Endpoint (SUR): Blood pressure
Study 18586644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3094360 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29750261 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24906029 — Surrogate Endpoint (SUR): Serum sodium
Study 22502793 — Safety Biomarker (SAF): Hyaluronic acid
Study 15631865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15631865 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9878016 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2189075 — Surrogate Endpoint (SUR): Blood pressure
Study 26206423 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 26206423 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 8126502 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 24019134 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 16951474 — Surrogate Endpoint (SUR): Bone mineral density
Study 31399793 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21696635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9275372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30552505 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31089253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31089253 — Surrogate Endpoint (SUR): Blood pressure
Study 30359215 — Surrogate Endpoint (SUR): Blood pressure
Study 30359215 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27865620 — Surrogate Endpoint (SUR): Blood pressure
Study 27865620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11235707 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28904068 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14967868 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 10977787 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 10977787 — Surrogate Endpoint (SUR): Serum calcium
Study 22393101 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22393101 — Predictive Biomarker (PRD): Hormone receptor
Study 16487032 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 24559003 — Surrogate Endpoint (SUR): Serum creatinine
Study 18356793 — Surrogate Endpoint (SUR): Blood pressure
Study 17210383 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16338562 — Safety Biomarker (SAF): Cytochrome c
Study 2223348 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25727104 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 15636216 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11078488 — Predictive Biomarker (PRD): Hormone receptor
Study 1857729 — Surrogate Endpoint (SUR): Blood pressure
Study 6409917 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 25493953 — Surrogate Endpoint (SUR): Blood pressure
Study 25493953 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23070057 — Surrogate Endpoint (SUR): Blood pressure
Study 19635719 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 19635719 — Safety Biomarker (SAF): Interleukin 1
Study 19635719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12885981 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9491504 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9098468 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 29759063 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 25064723 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25064723 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18555575 — Surrogate Endpoint (SUR): Blood pressure
Study 323298 — Surrogate Endpoint (SUR): Blood pressure
Study 24019047 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 19663521 — Surrogate Endpoint (SUR): Blood pressure
Study 30627512 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 20649060 — Surrogate Endpoint (SUR): Serum potassium
Study 18379501 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 16076940 — Surrogate Endpoint (SUR): Bone mineral density
Study 18946011 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16981000 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 15134308 — Surrogate Endpoint (SUR): Blood pressure
Study 24798786 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15756217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15756217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10693099 — Surrogate Endpoint (SUR): Serum sodium
Study 31670388 — Predictive Biomarker (PRD): BLK mRNA
Genes: BLK
Study 25814467 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 22087846 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18635446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18635446 — Surrogate Endpoint (SUR): Blood pressure
Study 12845731 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26197451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22343536 — Surrogate Endpoint (SUR): Blood pressure
Study 28376899 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25406260 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25406260 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23813322 — Surrogate Endpoint (SUR): Blood pressure
Study 21708042 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 19699875 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 1284152 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1284152 — Safety Biomarker (SAF): Cytochrome c
Study 29265934 — Surrogate Endpoint (SUR): Blood pressure
Study 12598351 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9890307 — Surrogate Endpoint (SUR): Blood pressure
Study 29902939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25475143 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 1613273 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 87965 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8467322 — Surrogate Endpoint (SUR): Blood pressure
Study 30344655 — Monitoring Biomarker (MOI): Procalcitonin
Study 30344655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30344655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30344655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11056593 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 11206674 — Surrogate Endpoint (SUR): Blood pressure
Study 6116607 — Surrogate Endpoint (SUR): Blood pressure
Study 23324658 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7512805 — Surrogate Endpoint (SUR): Blood pressure
Study 20827548 — Surrogate Endpoint (SUR): Bone mineral density
Study 19671398 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17453751 — Surrogate Endpoint (SUR): Blood pressure
Study 11926784 — Surrogate Endpoint (SUR): Blood pressure
Study 30720034 — Surrogate Endpoint (SUR): Blood pressure
Study 28865866 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 28865866 — Surrogate Endpoint (SUR): Blood pressure
Study 21576282 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21576282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21576282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21576282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12063773 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 12063773 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22119513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 15031571 — Surrogate Endpoint (SUR): Blood pressure
Study 9735578 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 8296409 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8296409 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2737789 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 820882 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16868063 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12601103 — Surrogate Endpoint (SUR): Bone mineral density
Study 24769189 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18194384 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15993933 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30225878 — Surrogate Endpoint (SUR): Blood pressure
Study 27710240 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 18626299 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14679383 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8439095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 3531452 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 27128665 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 27128665 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29683391 — Surrogate Endpoint (SUR): Blood pressure
Study 26979136 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28107273 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 25136625 — Surrogate Endpoint (SUR): Blood pressure
Study 15660859 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9058176 — Surrogate Endpoint (SUR): Blood pressure
Study 18088241 — Monitoring Biomarker (MOI): HBV DNA
Study 16527014 — Surrogate Endpoint (SUR): Blood pressure
Study 12866606 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29691246 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28716522 — Surrogate Endpoint (SUR): Blood pressure
Study 26179482 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26179482 — Surrogate Endpoint (SUR): Blood pressure
Study 21441078 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18202030 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22207070 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19955891 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17429784 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26589253 — Surrogate Endpoint (SUR): Blood pressure
Study 22717420 — Surrogate Endpoint (SUR): Blood pressure
Study 20151774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18082876 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 12399191 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 20379742 — Predictive Biomarker (PRD): Microsatellite instability
Study 10353863 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 10353863 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2057620 — Surrogate Endpoint (SUR): Blood pressure
Study 20519076 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9875065 — Predictive Biomarker (PRD): RTN1 mRNA
Genes: RTN1; NSP
Study 21261621 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21261621 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11106141 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9377067 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30409131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19000553 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19000553 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16308008 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 12617335 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10554126 — Surrogate Endpoint (SUR): Bone mineral density
Study 28767146 — Surrogate Endpoint (SUR): Blood pressure
Study 28767146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3146403 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23274785 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23274785 — Predictive Biomarker (PRD): OPN1SW mRNA
Genes: OPN1SW; BCP
Study 23274785 — Monitoring Biomarker (MOI): HBV DNA
Study 21649862 — Surrogate Endpoint (SUR): Blood pressure