TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29363343 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 29363760 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 29364886 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29365099 — Surrogate Endpoint (SUR): Bone mineral density
Study 29366580 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 29366580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29366580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29366960 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 29367268 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29368271 — Surrogate Endpoint (SUR): Bone mineral density
Study 29370218 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29370428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29371241 — Surrogate Endpoint (SUR): Blood pressure
Study 29371263 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 29371473 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29371475 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 29371475 — Predictive Biomarker (PRD): STK11 mRNA
Genes: STK11; LKB1; PJS
Study 29372461 — Predictive Biomarker (PRD): ST14 mRNA
Genes: ST14; PRSS14; SNC19; TADG15
Study 29373071 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29373711 — Predictive Biomarker (PRD): PAX8 mRNA
Genes: PAX8
Study 29373977 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29377378 — Surrogate Endpoint (SUR): Bone mineral density
Study 29377748 — Predictive Biomarker (PRD): ELOVL4 mRNA
Genes: ELOVL4
Study 29378632 — Surrogate Endpoint (SUR): Blood pressure
Study 29378632 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29379040 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29381435 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 29381795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29381826 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29381826 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29381843 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 29382504 — Surrogate Endpoint (SUR): Blood pressure
Study 29382504 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 29382747 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 29382747 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 29385370 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29385376 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29385399 — Surrogate Endpoint (SUR): Blood pressure
Study 29385837 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29386196 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 29386195 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 29386195 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29386249 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29387022 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 29387432 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 29387473 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 29388048 — Predictive Biomarker (PRD): WNT2 mRNA
Genes: WNT2; INT1L1; IRP
Study 29389444 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29392425 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 29392418 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29392450 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 29393219 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 29393219 — Surrogate Endpoint (SUR): Serum creatinine
Study 29393720 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29393720 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29394125 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29394125 — Predictive Biomarker (PRD): PDCD1LG2 mRNA
Genes: PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2
Study 29394251 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 29394884 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 29395172 — Surrogate Endpoint (SUR): Serum sodium
Study 29396389 — Surrogate Endpoint (SUR): Blood pressure
Study 29396857 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 29396857 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 29397019 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 29397019 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29397305 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study 29397305 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 29398518 — Surrogate Endpoint (SUR): Bone mineral density
Study 29398640 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29398998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29398998 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 29398998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29399976 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 29400693 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 29401002 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 29401002 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 29401002 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 29401002 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29401002 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29402187 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29402243 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29403482 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29403482 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 29403482 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29404723 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29405350 — Surrogate Endpoint (SUR): Blood pressure
Study 29405626 — Surrogate Endpoint (SUR): Serum creatinine
Study 29408205 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 29408205 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 29408715 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29408981 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29409871 — Safety Biomarker (SAF): Interleukin 12
Study 29409871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29410786 — Surrogate Endpoint (SUR): Blood pressure
Study 29413510 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 29413510 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29413684 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 29413684 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 29414920 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 29414995 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 29415190 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 29415190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29415580 — Surrogate Endpoint (SUR): Blood pressure
Study 29417430 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 29419425 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29419698 — Monitoring Biomarker (MOI): Cell-free DNA
Study 29420467 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29420467 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 29422039 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 29422070 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29423259 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 29423515 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29424248 — Surrogate Endpoint (SUR): Serum creatinine
Study 29424480 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 29424480 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29424480 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29424775 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29429815 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29430306 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29430747 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 29431103 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29431735 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study 29432154 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 29433525 — Surrogate Endpoint (SUR): Blood pressure
Study 29433573 — Surrogate Endpoint (SUR): Bone mineral density
Study 29433573 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29434012 — Surrogate Endpoint (SUR): Blood pressure
Study 29435364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29435364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29435776 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29435776 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29437243 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 29437243 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 29437243 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 29437243 — Surrogate Endpoint (SUR): Serum hemoglobin A1C
Study 29437243 — Safety Biomarker (SAF): Reactive oxygen species
Study 29437753 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29437753 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29437753 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29437753 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 29437753 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 29437753 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29437753 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29437753 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 29437753 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 29437944 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 29437944 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29438269 — Surrogate Endpoint (SUR): Blood pressure
Study 29438361 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 29438522 — Predictive Biomarker (PRD): WIF1 mRNA
Genes: WIF1; UNQ191/PRO217
Study 29438522 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 29438522 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 29438522 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29439003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29439084 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 29439084 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 29439084 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 29439084 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29439084 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29439084 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 29439084 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29439160 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 29439160 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 29439670 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 29439670 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 29439857 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29442437 — Predictive Biomarker (PRD): ID3 mRNA
Genes: ID3; 1R21; BHLHB25; HEIR1
Study 29444231 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29444926 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 29445030 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 29445030 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 29445030 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 29445374 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 29445520 — Surrogate Endpoint (SUR): Blood pressure
Study 29445583 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 29445583 — Predictive Biomarker (PRD): Chromosome 17p
Study 29445858 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29447240 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 29447240 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 29448936 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 29448936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29448936 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 29449193 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 29449941 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29449941 — Surrogate Endpoint (SUR): Blood pressure
Study 29450753 — Predictive Biomarker (PRD): Hormone receptor
Study 29451701 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 29451701 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 29451701 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29451701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 29451701 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29452209 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 29452209 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 29452209 — Predictive Biomarker (PRD): PRLR mRNA
Genes: PRLR
Study 29452351 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 29454306 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29454306 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29454321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 29454364 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 29455032 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 29456529 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29458388 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29458388 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 29458388 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 29459949 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 29459949 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 29460398 — Predictive Biomarker (PRD): SH3PXD2A mRNA
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study 29460699 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29461919 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29462123 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29462629 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 29463285 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29463490 — Surrogate Endpoint (SUR): Blood pressure
Study 29463490 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29463520 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29463520 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29464830 — Surrogate Endpoint (SUR): Blood pressure
Study 29464830 — Surrogate Endpoint (SUR): Serum creatinine
Study 29465308 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29466156 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 29466429 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 29466429 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 29467321 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 29469964 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 29470191 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 29470286 — Predictive Biomarker (PRD): CAMK1D mRNA
Genes: CAMK1D; CAMKID
Study 29470582 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 29471782 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29471782 — Safety Biomarker (SAF): IL-6 and IL-10
Study 29471876 — Surrogate Endpoint (SUR): Blood pressure
Study 29472030 — Surrogate Endpoint (SUR): Blood pressure
Study 29472310 — Surrogate Endpoint (SUR): Blood pressure
Study 29472357 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29472362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29473191 — Surrogate Endpoint (SUR): Bone mineral density
Study 29473191 — Surrogate Endpoint (SUR): Blood pressure
Study 29474345 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 29474345 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 29475723 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 29475762 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29476499 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 29476612 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29476612 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29476612 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29476876 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29477412 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 29477778 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29478026 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29478343 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 29478790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29478790 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29479473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29480210 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 29481659 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29482616 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29484198 — Predictive Biomarker (PRD): EEF1A2 mRNA
Genes: EEF1A2; EEF1AL; STN
Study 29486663 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 29486663 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 29486723 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29486869 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 29487070 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 29487193 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 29487193 — Surrogate Endpoint (SUR): Blood pressure
Study 29487697 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 29487697 — Predictive Biomarker (PRD): SLC35A2 mRNA
Genes: SLC35A2; UGALT; UGT; UGTL
Study 29487870 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 29488122 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29488122 — Surrogate Endpoint (SUR): Serum creatinine
Study 29488164 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 29490924 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29491412 — Pharmacodynamic Biomarker (PDY): Hexamethylene bis-acetamide-inducible protein 1
Genes: HEXIM1; CLP1; EDG1; HIS1; MAQ1
Study 29493578 — Monitoring Biomarker (MOI): Cell-free DNA
Study 29496167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29496167 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 29498038 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29498038 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 29498038 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 29498038 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29498296 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1