TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22207723 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 9546804 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7009256 — Surrogate Endpoint (SUR): Blood pressure
Study 19742334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19742334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19742334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28729021 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 8935222 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8935222 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1392444 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 27304841 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25144296 — Surrogate Endpoint (SUR): Blood pressure
Study 25808994 — Predictive Biomarker (PRD): ITK mRNA
Genes: ITK; EMT; LYK
Study 11588528 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2577692 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2577692 — Surrogate Endpoint (SUR): Blood pressure
Study 25174443 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9223025 — Surrogate Endpoint (SUR): Blood pressure
Study 27394029 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 20206835 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20206835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18319058 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 18319058 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16450827 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8693765 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31062264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31062264 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 31062264 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19850529 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 31104833 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31104833 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 28135050 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 28135050 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 23757034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23757034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23757034 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9124858 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10334683 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 20674311 — Surrogate Endpoint (SUR): Blood pressure
Study 31812878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31812878 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 26416604 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 26416604 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 26416604 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21078382 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 11753595 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9425508 — Surrogate Endpoint (SUR): Bone mineral density
Study 8503714 — Surrogate Endpoint (SUR): Blood pressure
Study 27302000 — Surrogate Endpoint (SUR): Blood pressure
Study 23250252 — Surrogate Endpoint (SUR): Blood pressure
Study 10408318 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 29483485 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 15975155 — Surrogate Endpoint (SUR): Blood pressure
Study 1468273 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20299238 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 8935189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8935189 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 24695352 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 24695352 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 24695352 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24695352 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 24695352 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 9237961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24176022 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 24176022 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 17228023 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17228023 — Predictive Biomarker (PRD): Microsatellite instability
Study 9627039 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 2967089 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31923341 — Surrogate Endpoint (SUR): Bone mineral density
Study 20185602 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30884788 — Predictive Biomarker (PRD): SFRP2 mRNA
Genes: SFRP2; FRP2; SARP1; FKSG12; UNQ361/PRO697
Study 30884788 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 26964159 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 29313180 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2271125 — Surrogate Endpoint (SUR): Serum potassium
Study 29992904 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 22221492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20684264 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12142111 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23522245 — Surrogate Endpoint (SUR): Blood pressure
Study 22083986 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22554102 — Safety Biomarker (SAF): Hyaluronic acid
Study 20981007 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 26113676 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16912578 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9436574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9436574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9436574 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30157683 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30157683 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25875425 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22457045 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 16385649 — Surrogate Endpoint (SUR): Bone mineral density
Study 10620210 — Surrogate Endpoint (SUR): Serum calcium
Study 21057561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15451149 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10021953 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10021953 — Surrogate Endpoint (SUR): Blood pressure
Study 25432788 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18562776 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10495050 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 1792411 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 30865916 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26355674 — Surrogate Endpoint (SUR): Bone mineral density
Study 22943633 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 21272897 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21272897 — Surrogate Endpoint (SUR): Serum creatinine
Study 21272897 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21272897 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18027183 — Surrogate Endpoint (SUR): Bacterial count
Study 2163450 — Surrogate Endpoint (SUR): Blood pressure
Study 20843313 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12510039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1829981 — Surrogate Endpoint (SUR): Blood pressure
Study 1829981 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27630326 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 24290600 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24290600 — Surrogate Endpoint (SUR): Blood pressure
Study 24290600 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24290600 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21631568 — Surrogate Endpoint (SUR): Blood pressure
Study 8458681 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15668474 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9709910 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7874900 — Surrogate Endpoint (SUR): Blood pressure
Study 31197095 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31197095 — Safety Biomarker (SAF): BDNF
Study 19469186 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 17767819 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 17767819 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27896921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26498958 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17317877 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15548244 — Predictive Biomarker (PRD): SRMS mRNA
Genes: SRMS; C20orf148
Study 3293631 — Surrogate Endpoint (SUR): Blood pressure
Study 30454042 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28027332 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 23316693 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 23316693 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 23316693 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 23316693 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 23316693 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 31165717 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 11225716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11225716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29259310 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 15513282 — Surrogate Endpoint (SUR): Bone mineral density
Study 9558016 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28591133 — Surrogate Endpoint (SUR): Blood pressure
Study 23661240 — Surrogate Endpoint (SUR): Bone mineral density
Study 21764469 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16943456 — Predictive Biomarker (PRD): APOA5 mRNA
Genes: APOA5; RAP3; UNQ411/PRO773
Study 18782780 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16815485 — Safety Biomarker (SAF): Interleukin 1
Study 16815485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16815485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16815485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2405883 — Surrogate Endpoint (SUR): Blood pressure
Study 25139667 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2492011 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2492011 — Monitoring Biomarker (MOI): HBV DNA
Study 26851187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9469683 — Surrogate Endpoint (SUR): Blood pressure
Study 9469683 — Surrogate Endpoint (SUR): Serum sodium
Study 31162894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31162894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17314110 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17314110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17314110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15205386 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 31201481 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 31201481 — Surrogate Endpoint (SUR): Bone mineral density
Study 28797427 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17623246 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25369272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14654744 — Surrogate Endpoint (SUR): Blood pressure
Study 27100959 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26620151 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24823461 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 20234892 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 18661687 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 15968954 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10231930 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1423942 — Surrogate Endpoint (SUR): Blood pressure
Study 30796651 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30796651 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30796651 — Predictive Biomarker (PRD): Hormone receptor
Study 22407494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22407494 — Surrogate Endpoint (SUR): Blood pressure
Study 2692687 — Surrogate Endpoint (SUR): Blood pressure
Study 22728166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22728166 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9354312 — Surrogate Endpoint (SUR): Blood pressure
Study 30905643 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30905643 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 30905643 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16312918 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 16312918 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30640308 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30640308 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31219000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31219000 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31219000 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 22036640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28118402 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 28118402 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21208354 — Surrogate Endpoint (SUR): Blood pressure
Study 11373466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24631386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24631386 — Safety Biomarker (SAF): IL-6 and IL-10
Study 23035743 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23035743 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12923650 — Safety Biomarker (SAF): Reactive oxygen species
Study 2529375 — Surrogate Endpoint (SUR): Blood pressure
Study 23247045 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 9032180 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9032180 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9032180 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9032180 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27579536 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27579536 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 27579536 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 27579536 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27579536 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12682838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17682090 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 1974143 — Surrogate Endpoint (SUR): Blood pressure
Study 10080158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31500661 — Surrogate Endpoint (SUR): Blood pressure
Study 25897676 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 17278974 — Surrogate Endpoint (SUR): Blood pressure
Study 17278974 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24296423 — Predictive Biomarker (PRD): SLC38A3 mRNA
Genes: SLC38A3; G17; NAT1; SN1; SNAT3
Study 15703774 — Surrogate Endpoint (SUR): Blood pressure
Study 11836455 — Surrogate Endpoint (SUR): Blood pressure
Study 1959686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6367380 — Surrogate Endpoint (SUR): Blood pressure
Study 25425308 — Predictive Biomarker (PRD): USH1C mRNA
Genes: USH1C; AIE75
Study 11860914 — Surrogate Endpoint (SUR): Blood pressure
Study 1432027 — Surrogate Endpoint (SUR): Blood pressure
Study 30876946 — Monitoring Biomarker (MOI): HBV DNA
Study 30876946 — Surrogate Endpoint (SUR): Bone mineral density
Study 29854085 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 29854085 — Surrogate Endpoint (SUR): Blood pressure
Study 22852055 — Surrogate Endpoint (SUR): Blood pressure
Study 19254123 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 17448057 — Surrogate Endpoint (SUR): Blood pressure
Study 26763917 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24240777 — Surrogate Endpoint (SUR): Blood pressure
Study 22093005 — Surrogate Endpoint (SUR): Probing pocket depth
Study 9163287 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8424580 — Surrogate Endpoint (SUR): Blood pressure
Study 31751317 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 27473187 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 19448211 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 19448211 — Surrogate Endpoint (SUR): Serum creatinine
Study 24814382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24814382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24814382 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3306291 — Surrogate Endpoint (SUR): Blood pressure
Study 3306291 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25821098 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 16162683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24614112 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22587593 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 22587593 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 22587593 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4