TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11345497 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11800172 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16206505 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8535198 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 2027271 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 2027271 — Surrogate Endpoint (SUR): Serum calcium
Study 24176222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17537742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17537742 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9517606 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18433494 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1513086 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 31464890 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 20926897 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 30625169 — Safety Biomarker (SAF): RFC1
Genes: A1; PO-GA; RFC140; MHCBFB
Study 17053267 — Surrogate Endpoint (SUR): Blood pressure
Study 12916659 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 22105051 — Surrogate Endpoint (SUR): Blood pressure
Study 16150110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12193522 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 12193522 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 9619619 — Surrogate Endpoint (SUR): Blood pressure
Study 7659768 — Surrogate Endpoint (SUR): Blood pressure
Study 30316888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23505057 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23505057 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 8989255 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 10814607 — Surrogate Endpoint (SUR): Blood pressure
Study 1879978 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29185490 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 26447089 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 26447089 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22542748 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19390538 — Surrogate Endpoint (SUR): Blood pressure
Study 16514819 — Surrogate Endpoint (SUR): Blood pressure
Study 23257428 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23257428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 9552024 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 7914118 — Surrogate Endpoint (SUR): Blood pressure
Study 23490092 — Safety Biomarker (SAF): Hyaluronic acid
Study 23490092 — Monitoring Biomarker (MOI): HBV DNA
Study 21192310 — Surrogate Endpoint (SUR): Serum creatinine
Study 8865958 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 19127033 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 18937609 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18937609 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14654745 — Surrogate Endpoint (SUR): Blood pressure
Study 22500384 — Monitoring Biomarker (MOI): HBV DNA
Study 20569451 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20569451 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15925752 — Surrogate Endpoint (SUR): Blood pressure
Study 12036194 — Surrogate Endpoint (SUR): Blood pressure
Study 12036194 — Surrogate Endpoint (SUR): Serum potassium
Study 12036194 — Surrogate Endpoint (SUR): Serum sodium
Study 26386702 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 26386702 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25632745 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23349296 — Surrogate Endpoint (SUR): Serum creatinine
Study 18523036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18523036 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18523036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26962106 — Surrogate Endpoint (SUR): Blood pressure
Study 23487599 — Surrogate Endpoint (SUR): Blood pressure
Study 19451442 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19451442 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12816740 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12816740 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 12816740 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12816740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10370734 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10370734 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8677206 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26799522 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 22285180 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22285180 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7835212 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 7835212 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 7835212 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7835212 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 2970855 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2970855 — Surrogate Endpoint (SUR): Blood pressure
Study 17494925 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11677200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3116695 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28767558 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25821958 — Predictive Biomarker (PRD): APLP1 mRNA
Genes: APLP1
Study 25821958 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 7700028 — Surrogate Endpoint (SUR): Serum creatinine
Study 2975995 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 23340794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23340794 — Surrogate Endpoint (SUR): Blood pressure
Study 23340794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23340794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8951985 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29514030 — Monitoring Biomarker (MOI): HBV DNA
Study 21058483 — Safety Biomarker (SAF): IL-6 and IL-10
Study 26202594 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 26202594 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 17297382 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9653434 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 2273080 — Surrogate Endpoint (SUR): Blood pressure
Study 17530471 — Surrogate Endpoint (SUR): Bone mineral density
Study 17530471 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26481083 — Surrogate Endpoint (SUR): Blood pressure
Study 24586490 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 9972769 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 1683332 — Surrogate Endpoint (SUR): Blood pressure
Study 31937586 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 30893638 — Predictive Biomarker (PRD): STRA8 mRNA
Genes: STRA8
Study 17464718 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 17464718 — Safety Biomarker (SAF): BDNF
Study 15163892 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 15163892 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15163892 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15163892 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20043136 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 17652642 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 20980215 — Surrogate Endpoint (SUR): Blood pressure
Study 11841593 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10445787 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 6986970 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 21558406 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2676266 — Surrogate Endpoint (SUR): Blood pressure
Study 18361803 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 3064599 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25578927 — Surrogate Endpoint (SUR): Blood pressure
Study 25578927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25578927 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20697938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20697938 — Safety Biomarker (SAF): Hyaluronic acid
Study 20697938 — Safety Biomarker (SAF): Interleukin 1
Study 20697938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27715348 — Safety Biomarker (SAF): Reactive oxygen species
Study 19958962 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 18173140 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 7129293 — Surrogate Endpoint (SUR): Blood pressure
Study 31917835 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22306585 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19161766 — Surrogate Endpoint (SUR): Serum creatinine
Study 28522812 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 18290565 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15613978 — Safety Biomarker (SAF): Reactive oxygen species
Study 7739947 — Surrogate Endpoint (SUR): Serum creatinine
Study 22855581 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 22855581 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22855581 — Predictive Biomarker (PRD): PAK1 mRNA
Genes: PAK1
Study 12046341 — Surrogate Endpoint (SUR): Blood pressure
Study 12046341 — Surrogate Endpoint (SUR): Serum creatinine
Study 29479872 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 27439448 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 27439448 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 20850556 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 12196335 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12196335 — Surrogate Endpoint (SUR): Blood pressure
Study 1947853 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 6830658 — Surrogate Endpoint (SUR): Blood pressure
Study 25226360 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25226360 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 31078482 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31078482 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16828477 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12492794 — Surrogate Endpoint (SUR): Blood pressure
Study 30999886 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 25817226 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25817226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22872427 — Surrogate Endpoint (SUR): Serum sodium
Study 3289874 — Surrogate Endpoint (SUR): Blood pressure
Study 20812949 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20812949 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19924605 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19924605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19924605 — Surrogate Endpoint (SUR): Blood pressure
Study 16824993 — Surrogate Endpoint (SUR): Blood pressure
Study 21967443 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15662233 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15662233 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15662233 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15662233 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10552992 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 19093336 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9665011 — Predictive Biomarker (PRD): CA2 mRNA
Genes: CA2
Study 24516261 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24516261 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22545737 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21142446 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12386638 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7581094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30650479 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26486191 — Surrogate Endpoint (SUR): Blood pressure
Study 24755046 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15358033 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 15358033 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 15358033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7666064 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study 2474848 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29482026 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28352985 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28352985 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 28352985 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 28352985 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20441725 — Surrogate Endpoint (SUR): Blood pressure
Study 23759449 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 8766415 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3299089 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29317123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27716324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24388336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16127964 — Safety Biomarker (SAF): DRD2
Study 4051446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 4051446 — Surrogate Endpoint (SUR): Serum calcium
Study 4051446 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30527176 — Predictive Biomarker (PRD): Leucine-rich alpha-2-glycoprotein
Genes: LRG1; LRG
Study 27433858 — Surrogate Endpoint (SUR): Bone mineral density
Study 16098604 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16098604 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 6535339 — Surrogate Endpoint (SUR): Blood pressure
Study 30665671 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18817993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18817993 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18817993 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2323312 — Surrogate Endpoint (SUR): Blood pressure
Study 9175978 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31939996 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 24074710 — Safety Biomarker (SAF): Hyaluronic acid
Study 6388012 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 23044180 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12065457 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 19279381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31088111 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28146402 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 28146402 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 28146402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21262998 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21262998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18647203 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10930202 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10930202 — Surrogate Endpoint (SUR): Blood pressure
Study 8105072 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28994192 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25599119 — Surrogate Endpoint (SUR): Blood pressure
Study 18675269 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 14503059 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29882961 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 23139603 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 11313177 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8427957 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29268139 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16600235 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12955552 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 1330398 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1330398 — Surrogate Endpoint (SUR): Blood pressure
Study 29084397 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 12592232 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26914684 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 9699222 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 2524992 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 12596107 — Surrogate Endpoint (SUR): Serum testosterone
Study 10509041 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10509041 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23138014 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21253715 — Surrogate Endpoint (SUR): Bone mineral density
Study 18209674 — Surrogate Endpoint (SUR): Serum sodium
Study 16803420 — Surrogate Endpoint (SUR): Blood pressure
Study 20686499 — Surrogate Endpoint (SUR): Blood pressure
Study 27818472 — Surrogate Endpoint (SUR): Blood pressure
Study 18926076 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18926076 — Surrogate Endpoint (SUR): Blood pressure
Study 15751094 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9769027 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 8556421 — Surrogate Endpoint (SUR): Blood pressure
Study 30559073 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28003574 — Surrogate Endpoint (SUR): Serum creatinine
Study 3308720 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 27881145 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19969446 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10232717 — Surrogate Endpoint (SUR): Blood pressure
Study 1748136 — Surrogate Endpoint (SUR): Blood pressure
Study 31067138 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 22266992 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 15359376 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30886334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30886334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28720132 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 15870668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30301473 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 25554404 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25554404 — Surrogate Endpoint (SUR): Serum potassium
Study 25554404 — Safety Biomarker (SAF): Cystatin C
Genes: CST3