TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27196764 — Predictive Biomarker (PRD): TLR1 mRNA
Genes: TLR1; KIAA0012
Study 27196764 — Predictive Biomarker (PRD): MAP3K7 mRNA
Genes: MAP3K7; TAK1
Study 12714874 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2996905 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 28002896 — Safety Biomarker (SAF): Hyaluronic acid
Study 20595643 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 20595643 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16236040 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16236040 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 9142512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 9142512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 31809308 — Predictive Biomarker (PRD): PPP1R13L mRNA
Genes: PPP1R13L; IASPP; NKIP1; PPP1R13BL; RAI
Study 30790345 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 30790345 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19858123 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 18925316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7971646 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29121282 — Surrogate Endpoint (SUR): Serum potassium
Study 23761484 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 1317694 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27460602 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 15855257 — Surrogate Endpoint (SUR): Bone mineral density
Study 22193575 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 16140224 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7599565 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 6104498 — Surrogate Endpoint (SUR): Blood pressure
Study 23434769 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 17657857 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17657857 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26139 — Surrogate Endpoint (SUR): Blood pressure
Study 31758576 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 31758576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31758576 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23818488 — Surrogate Endpoint (SUR): Blood pressure
Study 9591935 — Surrogate Endpoint (SUR): Blood pressure
Study 2533057 — Surrogate Endpoint (SUR): Blood pressure
Study 23265698 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21593252 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 16478899 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9088653 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 6822143 — Surrogate Endpoint (SUR): Blood pressure
Study 18783774 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18783774 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23873339 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11423920 — Surrogate Endpoint (SUR): Blood pressure
Study 27498355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27498355 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27238921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27238921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19783106 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 2193199 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26228496 — Safety Biomarker (SAF): Hyaluronic acid
Study 11015150 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8790092 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24091935 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 16207425 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16207425 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16207425 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 16207425 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12463459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11910672 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15928801 — Surrogate Endpoint (SUR): Bone mineral density
Study 7774515 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7774515 — Surrogate Endpoint (SUR): Blood pressure
Study 27224980 — Predictive Biomarker (PRD): STT3A mRNA
Genes: STT3A; ITM1; TMC
Study 19803419 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17557771 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 28595250 — Safety Biomarker (SAF): Hyaluronic acid
Study 21306414 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16495394 — Surrogate Endpoint (SUR): Bone mineral density
Study 29164649 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29164649 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17762964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25641922 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 19148563 — Surrogate Endpoint (SUR): Bone mineral density
Study 11564386 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11564386 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9784902 — Surrogate Endpoint (SUR): Blood pressure
Study 10225047 — Surrogate Endpoint (SUR): Blood pressure
Study 3367001 — Surrogate Endpoint (SUR): Blood pressure
Study 27027501 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27027501 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23535525 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6452802 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17135064 — Surrogate Endpoint (SUR): Blood pressure
Study 11466161 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7821093 — Monitoring Biomarker (MOI): HBV DNA
Study 30360960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30360960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20025830 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 15866255 — Surrogate Endpoint (SUR): Blood pressure
Study 10645328 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1353933 — Surrogate Endpoint (SUR): Blood pressure
Study 6355394 — Surrogate Endpoint (SUR): Blood pressure
Study 28573820 — Surrogate Endpoint (SUR): Blood pressure
Study 18577834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18577834 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11310906 — Surrogate Endpoint (SUR): Serum calcium
Study 29985113 — Surrogate Endpoint (SUR): Blood pressure
Study 27078992 — Surrogate Endpoint (SUR): Blood pressure
Study 15711996 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 12468916 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 12468916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10424370 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29764447 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 19965584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 27455166 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 18417275 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 12829912 — Surrogate Endpoint (SUR): Serum creatinine
Study 3241278 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3241278 — Surrogate Endpoint (SUR): Blood pressure
Study 27089126 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21087332 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11501357 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 8554360 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2528578 — Surrogate Endpoint (SUR): Blood pressure
Study 18819901 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 18819901 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 12707230 — Surrogate Endpoint (SUR): Serum creatinine
Study 7449300 — Surrogate Endpoint (SUR): Blood pressure
Study 21110174 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 21110174 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 21110174 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 7601292 — Surrogate Endpoint (SUR): Blood pressure
Study 7601292 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7601292 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26732187 — Surrogate Endpoint (SUR): Blood pressure
Study 25312265 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18327605 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17761579 — Surrogate Endpoint (SUR): Blood pressure
Study 17761579 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11465647 — Surrogate Endpoint (SUR): Blood pressure
Study 9762658 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15998356 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10882858 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30012641 — Surrogate Endpoint (SUR): Serum creatinine
Study 18576903 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 12455724 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 31532136 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17235610 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 10899240 — Surrogate Endpoint (SUR): Blood pressure
Study 9401929 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24920270 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24920270 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16097043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12135314 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23077972 — Surrogate Endpoint (SUR): Blood pressure
Study 9334909 — Surrogate Endpoint (SUR): Blood pressure
Study 30706575 — Surrogate Endpoint (SUR): Blood pressure
Study 26137575 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26137575 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31983605 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 27097977 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 23259453 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16611389 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 16611389 — Safety Biomarker (SAF): Reactive oxygen species
Study 25678394 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17461928 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17461928 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9273008 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9273008 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9273008 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25039997 — Surrogate Endpoint (SUR): Blood pressure
Study 22230154 — Surrogate Endpoint (SUR): Serum creatinine
Study 18487550 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11204323 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11204323 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31147367 — Surrogate Endpoint (SUR): Serum uric acid
Study 31147367 — Surrogate Endpoint (SUR): Blood pressure
Study 31147367 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27403531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25023152 — Surrogate Endpoint (SUR): Blood pressure
Study 2140743 — Surrogate Endpoint (SUR): Blood pressure
Study 29315665 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29315665 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 21925813 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16495752 — Surrogate Endpoint (SUR): Blood pressure
Study 31968622 — Predictive Biomarker (PRD): GMCL2 mRNA
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 15707562 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 8706295 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 6689490 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 31495601 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31495601 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 23784898 — Surrogate Endpoint (SUR): Blood pressure
Study 24903544 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 11439380 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 6986409 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 21523719 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 6845123 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 16416346 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1352662 — Surrogate Endpoint (SUR): Blood pressure
Study 30979733 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 25465416 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 20451694 — Surrogate Endpoint (SUR): Blood pressure
Study 6365350 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30103622 — Surrogate Endpoint (SUR): Serum potassium
Study 16006454 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11954782 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 10049281 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9236429 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23497514 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 14621848 — Surrogate Endpoint (SUR): Serum creatinine
Study 31086287 — Predictive Biomarker (PRD): SCGB1A1 mRNA
Genes: SCGB1A1; CC10; CCSP; UGB
Study 29972633 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 29972633 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19088171 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19088171 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12133363 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28403662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28403662 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23867129 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30894441 — Surrogate Endpoint (SUR): Blood pressure
Study 20110375 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 20110375 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 10424376 — Predictive Biomarker (PRD): VILL mRNA
Genes: VILL
Study 1711614 — Surrogate Endpoint (SUR): Blood pressure
Study 27773851 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 27773851 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 27513252 — Surrogate Endpoint (SUR): Blood pressure
Study 20149706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 20149706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15802975 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31006728 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31006728 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31006728 — Surrogate Endpoint (SUR): Serum creatinine
Study 31006728 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 31006728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21784839 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 24824633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24824633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24824633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12833203 — Surrogate Endpoint (SUR): Blood pressure
Study 2859043 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16162882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28971360 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 23824103 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22089721 — Surrogate Endpoint (SUR): Blood pressure
Study 15377354 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 11164856 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26684170 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20926948 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 20926948 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 10601131 — Surrogate Endpoint (SUR): Blood pressure
Study 10601131 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24692535 — Surrogate Endpoint (SUR): Blood pressure
Study 24692535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22564993 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 22564993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31801725 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 24590053 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 31910279 — Surrogate Endpoint (SUR): Sperm parameters
Study 31291989 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28679140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23837141 — Monitoring Biomarker (MOI): HBV DNA
Study 22084369 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 28643427 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 27378812 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 25111123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25111123 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9653015 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 9653015 — Safety Biomarker (SAF): HLA-DRB1 and HLA-DQB1
Study 9653015 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 8281625 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28768173 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28768173 — Predictive Biomarker (PRD): GIPR mRNA
Genes: GIPR
Study 7794571 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 7794571 — Surrogate Endpoint (SUR): Blood pressure
Study 380386 — Surrogate Endpoint (SUR): Blood pressure
Study 29143122 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 29143122 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23945138 — Surrogate Endpoint (SUR): Blood pressure
Study 18622144 — Predictive Biomarker (PRD): F13B mRNA
Genes: F13B
Study 16860068 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10971105 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 8569467 — Surrogate Endpoint (SUR): Serum creatinine
Study 1379376 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12823852 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 12823852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10658377 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8557059 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31158840 — Surrogate Endpoint (SUR): Blood pressure
Study 21415814 — Surrogate Endpoint (SUR): Blood pressure
Study 15351581 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20357174 — Predictive Biomarker (PRD): Hormone receptor
Study 19337553 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11029334 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3914839 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12137243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9740934 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 2220622 — Surrogate Endpoint (SUR): Blood pressure
Study 10583422 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP