TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12873921 — Surrogate Endpoint (SUR): Blood pressure
Study 20975461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20975461 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 12971422 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 29658440 — Surrogate Endpoint (SUR): Blood pressure
Study 25249415 — Surrogate Endpoint (SUR): Blood pressure
Study 25249415 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22251435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22251435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28704492 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 28704492 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 23584289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 23584289 — Predictive Biomarker (PRD): GCLC mRNA
Genes: GCLC; GLCL; GLCLC
Study 23584289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 23584289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 23584289 — Safety Biomarker (SAF): miR-30e
Genes: MIR30E
Study 21721593 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21721593 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 21721593 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21721593 — Surrogate Endpoint (SUR): Blood pressure
Study 21721593 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19081394 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15295717 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15295717 — Surrogate Endpoint (SUR): Blood pressure
Study 26630643 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8562400 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8562400 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25539757 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 15829533 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12860943 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 9282581 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22011640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20329618 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 11594407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11594407 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7527565 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 26488347 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31712335 — Surrogate Endpoint (SUR): Blood pressure
Study 26812515 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24448644 — Surrogate Endpoint (SUR): Blood pressure
Study 18021336 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3793199 — Surrogate Endpoint (SUR): Blood pressure
Study 7705196 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 18940387 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2481772 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 2481772 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2481772 — Surrogate Endpoint (SUR): Blood pressure
Study 236075 — Surrogate Endpoint (SUR): Blood pressure
Study 31419298 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31419298 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31419298 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31419298 — Predictive Biomarker (PRD): H3-3A mRNA
Genes: H3-3A; H3.3A; H3F3; H3F3A; PP781;; H3-3B; H3.3B; H3F3B
Study 31419298 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21421502 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11252116 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22142891 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8958191 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22613001 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 19551536 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 17935245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17935245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2112022 — Surrogate Endpoint (SUR): Blood pressure
Study 21330636 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21330636 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18637139 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 14717388 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3020703 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 24998403 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 19358495 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22592178 — Surrogate Endpoint (SUR): Blood pressure
Study 12535822 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 12535822 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 2125605 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11169020 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 970905 — Surrogate Endpoint (SUR): Serum potassium
Study 31841354 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31841354 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 31841354 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31841354 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 30971437 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22208783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12828845 — Predictive Biomarker (PRD): PIR mRNA
Genes: PIR
Study 8813918 — Surrogate Endpoint (SUR): Serum sodium
Study 3910303 — Surrogate Endpoint (SUR): Blood pressure
Study 20827268 — Safety Biomarker (SAF): Reactive oxygen species
Study 12075577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12075577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12032722 — Surrogate Endpoint (SUR): Serum creatinine
Study 9661611 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 16860808 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22796996 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12574806 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 12574806 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10501793 — Surrogate Endpoint (SUR): Bone mineral density
Study 10501793 — Surrogate Endpoint (SUR): Serum testosterone
Study 10501793 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26713821 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26713821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7600753 — Surrogate Endpoint (SUR): Blood pressure
Study 7600753 — Surrogate Endpoint (SUR): Serum triglycerides
Study 1516498 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30782512 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 30782512 — Safety Biomarker (SAF): BDNF
Study 25577741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25577741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25577741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30803843 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 20824151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20824151 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10546012 — Surrogate Endpoint (SUR): Blood pressure
Study 29217959 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29217959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14705221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9630144 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3284292 — Surrogate Endpoint (SUR): Blood pressure
Study 26625505 — Surrogate Endpoint (SUR): Blood pressure
Study 23445666 — Surrogate Endpoint (SUR): Blood pressure
Study 12753258 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 6996111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31826931 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 21411411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19153829 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22068425 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 18689371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18689371 — Surrogate Endpoint (SUR): Bone mineral density
Study 18689371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15331394 — Safety Biomarker (SAF): Hyaluronic acid
Study 11425926 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9402534 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 2441162 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2441162 — Surrogate Endpoint (SUR): Blood pressure
Study 29030287 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28484897 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 10919933 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28095051 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 3310639 — Surrogate Endpoint (SUR): Blood pressure
Study 31102684 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 31102684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31102684 — Predictive Biomarker (PRD): DCN mRNA
Genes: DCN; SLRR1B
Study 25467199 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8719187 — Surrogate Endpoint (SUR): Blood pressure
Study 25740578 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25740578 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 12970783 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12970783 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28556500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20100913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16627043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11048993 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 30354996 — Surrogate Endpoint (SUR): Blood pressure
Study 25031198 — Surrogate Endpoint (SUR): Blood pressure
Study 12218528 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16082623 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10409478 — Surrogate Endpoint (SUR): Blood pressure
Study 26218077 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24448738 — Predictive Biomarker (PRD): MLXIPL mRNA
Genes: MLXIPL; BHLHD14; MIO; WBSCR14
Study 21996130 — Predictive Biomarker (PRD): MTLN mRNA
Genes: MTLN; LEMP; LINC00116; MOXI; MPM; NCRNA00116; SMIM37
Study 21996130 — Surrogate Endpoint (SUR): Blood pressure
Study 12895195 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10373050 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30726897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29924912 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 23039709 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 11327244 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 29091979 — Surrogate Endpoint (SUR): Blood pressure
Study 26620191 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 19938710 — Surrogate Endpoint (SUR): Blood pressure
Study 31315668 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31315668 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31315668 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 27358173 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27358173 — Surrogate Endpoint (SUR): Serum creatinine
Study 17609307 — Surrogate Endpoint (SUR): Serum calcium
Study 11473071 — Surrogate Endpoint (SUR): Blood pressure
Study 20137762 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17667565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16146460 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 2384192 — Surrogate Endpoint (SUR): Blood pressure
Study 27601592 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27601592 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15529256 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15529256 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 17058830 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17058830 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 17058830 — Surrogate Endpoint (SUR): Serum creatinine
Study 17058830 — Surrogate Endpoint (SUR): Blood pressure
Study 14762655 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14762655 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9216708 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7853678 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 29151700 — Monitoring Biomarker (MOI): HBV DNA
Study 25784709 — Surrogate Endpoint (SUR): Blood pressure
Study 25784709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18430311 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 17003665 — Predictive Biomarker (PRD): ENPP2 mRNA
Genes: ENPP2; ATX; PDNP2
Study 30423587 — Surrogate Endpoint (SUR): Blood pressure
Study 18025885 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21242686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21242686 — Safety Biomarker (SAF): Reactive oxygen species
Study 21242686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28376815 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19702088 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 19702088 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 19702088 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 16763508 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10898408 — Surrogate Endpoint (SUR): Blood pressure
Study 27065001 — Surrogate Endpoint (SUR): Blood pressure
Study 1656730 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1656730 — Surrogate Endpoint (SUR): Blood pressure
Study 24833327 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 18813043 — Surrogate Endpoint (SUR): Blood pressure
Study 30821115 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 28376214 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 28376214 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 28376214 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21927793 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8821690 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 31821361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24659740 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 24659740 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 24659740 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 24659740 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 24659740 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 24659740 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 24659740 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 24659740 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 7595907 — Surrogate Endpoint (SUR): Blood pressure
Study 7595907 — Surrogate Endpoint (SUR): Serum potassium
Study 2082005 — Surrogate Endpoint (SUR): Blood pressure
Study 28634728 — Surrogate Endpoint (SUR): Blood pressure
Study 19489487 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19489487 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8192275 — Surrogate Endpoint (SUR): Blood pressure
Study 3285763 — Surrogate Endpoint (SUR): Blood pressure
Study 10908079 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8612391 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 25630248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25630248 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25630248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18502255 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29423501 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 27118206 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 29220885 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26202165 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 26202165 — Predictive Biomarker (PRD): TPSG1 mRNA
Genes: TPSG1; PRSS31; TMT
Study 20939080 — Predictive Biomarker (PRD): GLI2 mRNA
Genes: GLI2; THP
Study 8853082 — Surrogate Endpoint (SUR): Blood pressure
Study 25157723 — Surrogate Endpoint (SUR): Blood pressure
Study 20627502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17492340 — Safety Biomarker (SAF): Hyaluronic acid
Study 2950827 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 27076209 — Predictive Biomarker (PRD): GRIN3A mRNA
Genes: GRIN3A; KIAA1973
Study 27076209 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 24722932 — Surrogate Endpoint (SUR): Blood pressure
Study 20361391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20361391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20361391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15964160 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7005415 — Surrogate Endpoint (SUR): Serum sodium
Study 7005415 — Surrogate Endpoint (SUR): Serum potassium
Study 2316838 — Surrogate Endpoint (SUR): Blood pressure
Study 27059729 — Predictive Biomarker (PRD): KRT16 mRNA
Genes: KRT16; KRT16A
Study 17601461 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 25519790 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12632024 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10692268 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10692268 — Surrogate Endpoint (SUR): Blood pressure
Study 3949999 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 23715625 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9555791 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 204183 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15624548 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 11768322 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18261561 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 18261561 — Surrogate Endpoint (SUR): Serum creatinine
Study 12933387 — Surrogate Endpoint (SUR): Blood pressure
Study 27161611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2