TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24614605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24614605 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24614605 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 25298575 — Surrogate Endpoint (SUR): Blood pressure
Study 21134821 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12578781 — Surrogate Endpoint (SUR): Blood pressure
Study 10547209 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 1801688 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30842213 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17507365 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 17507365 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16327033 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 282084 — Surrogate Endpoint (SUR): Blood pressure
Study 23332366 — Predictive Biomarker (PRD): NEB mRNA
Genes: NEB
Study 19498438 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19498438 — Surrogate Endpoint (SUR): Blood pressure
Study 17201277 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1775603 — Surrogate Endpoint (SUR): Blood pressure
Study 10220835 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 10220835 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 7604787 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7604787 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31503048 — Surrogate Endpoint (SUR): Blood pressure
Study 23758736 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 20053471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20053471 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20053471 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 30183583 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 30183583 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9504817 — Predictive Biomarker (PRD): HSP90B1 mRNA
Genes: HSP90B1; GRP94; TRA1
Study 9504817 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 9504817 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 9504817 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 3786603 — Surrogate Endpoint (SUR): Blood pressure
Study 19713950 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18652113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15975300 — Safety Biomarker (SAF): Hyaluronic acid
Study 1406078 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3902912 — Surrogate Endpoint (SUR): Blood pressure
Study 27846344 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 27846344 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20820916 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 20820916 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18549466 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18549466 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 11292011 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 11292011 — Surrogate Endpoint (SUR): Blood pressure
Study 3221745 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3221745 — Surrogate Endpoint (SUR): Blood pressure
Study 22642937 — Safety Biomarker (SAF): Cytochrome c
Study 2645120 — Surrogate Endpoint (SUR): Blood pressure
Study 6769666 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 11793634 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 799561 — Surrogate Endpoint (SUR): Blood pressure
Study 31483155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15238773 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15238773 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 8363210 — Surrogate Endpoint (SUR): Blood pressure
Study 3534801 — Surrogate Endpoint (SUR): Blood pressure
Study 3534801 — Surrogate Endpoint (SUR): Serum potassium
Study 30890817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30890817 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10423078 — Surrogate Endpoint (SUR): Blood pressure
Study 2580164 — Surrogate Endpoint (SUR): Blood pressure
Study 2580164 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30827252 — Surrogate Endpoint (SUR): Blood pressure
Study 23128163 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 23128163 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16632842 — Surrogate Endpoint (SUR): Blood pressure
Study 26224543 — Surrogate Endpoint (SUR): Blood pressure
Study 22658688 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 22658688 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 12732880 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12732880 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10199772 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 1723456 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1723456 — Surrogate Endpoint (SUR): Blood pressure
Study 22431131 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11999569 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 24993098 — Surrogate Endpoint (SUR): Blood pressure
Study 11788225 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7211734 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7211734 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7211734 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31983312 — Surrogate Endpoint (SUR): Blood pressure
Study 25828601 — Predictive Biomarker (PRD): SLBP mRNA
Genes: SLBP; HBP
Study 19280831 — Surrogate Endpoint (SUR): Probing pocket depth
Study 2551204 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28614905 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19298202 — Surrogate Endpoint (SUR): Blood pressure
Study 19298202 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19298202 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11276502 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29104121 — Predictive Biomarker (PRD): ISG15 mRNA
Genes: ISG15; G1P2; UCRP
Study 19807952 — Surrogate Endpoint (SUR): Blood pressure
Study 9284852 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 1329673 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 1329673 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31605792 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30442122 — Surrogate Endpoint (SUR): Blood pressure
Study 26369526 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 24481719 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24481719 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2732023 — Surrogate Endpoint (SUR): Blood pressure
Study 10852983 — Surrogate Endpoint (SUR): Serum calcium
Study 28986703 — Surrogate Endpoint (SUR): Blood pressure
Study 12633543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10687671 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3299394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12865480 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 17218573 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21701528 — Predictive Biomarker (PRD): ARHGEF5 mRNA
Genes: ARHGEF5; TIM
Study 19433694 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16675323 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16124647 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 30778667 — Predictive Biomarker (PRD): KLK3 mRNA
Genes: KLK3; APS
Study 29395188 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 27872863 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 24136652 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 12425849 — Surrogate Endpoint (SUR): Blood pressure
Study 31227872 — Predictive Biomarker (PRD): ARID5B mRNA
Genes: ARID5B; DESRT; MRF2
Study 19770393 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17324738 — Surrogate Endpoint (SUR): Blood pressure
Study 24120216 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 14555558 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26257209 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 9796636 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 24477618 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15992517 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15992517 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31154309 — Surrogate Endpoint (SUR): Blood pressure
Study 22179079 — Surrogate Endpoint (SUR): Blood pressure
Study 17693888 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17693888 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15177064 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 7597693 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 23570863 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17881750 — Surrogate Endpoint (SUR): Blood pressure
Study 12548591 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 12548591 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 12548591 — Surrogate Endpoint (SUR): Serum calcium
Study 8780281 — Surrogate Endpoint (SUR): Blood pressure
Study 1293241 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 31014399 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15014007 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 27656054 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 27656054 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 22747899 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 14582037 — Surrogate Endpoint (SUR): Serum creatinine
Study 22529265 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 18480825 — Surrogate Endpoint (SUR): Bone mineral density
Study 1337459 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1337459 — Surrogate Endpoint (SUR): Blood pressure
Study 29772111 — Surrogate Endpoint (SUR): Serum testosterone
Study 27578477 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 24573184 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 12574183 — Surrogate Endpoint (SUR): Blood pressure
Study 12574183 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10645516 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6772302 — Surrogate Endpoint (SUR): Blood pressure
Study 6550482 — Surrogate Endpoint (SUR): Serum creatinine
Study 24347426 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 24347426 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 24347426 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 21098449 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21098449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18295412 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 20929599 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8869674 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 12532366 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 12532366 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12532366 — Surrogate Endpoint (SUR): Blood pressure
Study 23719148 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20499312 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21757334 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22451449 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25877748 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17893579 — Surrogate Endpoint (SUR): Blood pressure
Study 15591955 — Surrogate Endpoint (SUR): Serum creatinine
Study 7943835 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7943835 — Surrogate Endpoint (SUR): Blood pressure
Study 3508193 — Surrogate Endpoint (SUR): Blood pressure
Study 25185593 — Surrogate Endpoint (SUR): Serum creatinine
Study 25185593 — Surrogate Endpoint (SUR): Serum potassium
Study 31648461 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 28533226 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 25643353 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 25643353 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 21316089 — Surrogate Endpoint (SUR): Serum creatinine
Study 19635156 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 19635156 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19635156 — Predictive Biomarker (PRD): IMPDH1 mRNA
Genes: IMPDH1; IMPD1
Study 29339649 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29339649 — Safety Biomarker (SAF): BDNF
Study 10929163 — Safety Biomarker (SAF): Interleukin 1
Study 25403903 — Surrogate Endpoint (SUR): Bone mineral density
Study 24771706 — Surrogate Endpoint (SUR): Blood pressure
Study 14769778 — Safety Biomarker (SAF): MTHFR
Study 12365087 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7983527 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 3142412 — Surrogate Endpoint (SUR): Blood pressure
Study 16803844 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 12717216 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 28982517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15933977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15933977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12856119 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6153057 — Surrogate Endpoint (SUR): Blood pressure
Study 26482279 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26482279 — Surrogate Endpoint (SUR): Serum calcium
Study 22827783 — Surrogate Endpoint (SUR): Bone mineral density
Study 29653858 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 21812797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17640853 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17640853 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 31739848 — Surrogate Endpoint (SUR): Blood pressure
Study 29851204 — Predictive Biomarker (PRD): ISG15 mRNA
Genes: ISG15; G1P2; UCRP
Study 29851204 — Monitoring Biomarker (MOI): HBV DNA
Study 9497787 — Surrogate Endpoint (SUR): Blood pressure
Study 7930694 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29863451 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18061705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 26777745 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26777745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23842100 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 12788993 — Surrogate Endpoint (SUR): Blood pressure
Study 12788993 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12788993 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31420399 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27586837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17391154 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23135976 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23135976 — Surrogate Endpoint (SUR): Blood pressure
Study 20551485 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15240609 — Surrogate Endpoint (SUR): Bone mineral density
Study 15240609 — Surrogate Endpoint (SUR): Serum calcium
Study 11816513 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 2880804 — Surrogate Endpoint (SUR): Blood pressure
Study 23227315 — Surrogate Endpoint (SUR): Blood pressure
Study 28939581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28939581 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 21685235 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21685235 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21685235 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 21685235 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21685235 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 16487220 — Surrogate Endpoint (SUR): Serum testosterone
Study 10321913 — Surrogate Endpoint (SUR): Bone mineral density
Study 7711430 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7711430 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3330985 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19217154 — Safety Biomarker (SAF): Interleukin 12
Study 11206682 — Surrogate Endpoint (SUR): Blood pressure
Study 9028542 — Surrogate Endpoint (SUR): Bone mineral density
Study 2661734 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31368422 — Surrogate Endpoint (SUR): Serum uric acid
Study 26002690 — Surrogate Endpoint (SUR): Blood pressure
Study 19621425 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 19621425 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 15544589 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 16313478 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16313478 — Surrogate Endpoint (SUR): Blood pressure
Study 12484506 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12484506 — Surrogate Endpoint (SUR): Blood pressure
Study 6115654 — Surrogate Endpoint (SUR): Blood pressure
Study 30407895 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30407895 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 11593318 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 21757931 — Predictive Biomarker (PRD): SPIN1 mRNA
Genes: SPIN1; OCR; SPIN
Study 11318504 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11318504 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31420830 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 31420830 — Surrogate Endpoint (SUR): Bone mineral density
Study 15519184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15843228 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7309298 — Surrogate Endpoint (SUR): Blood pressure
Study 15086213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15086213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15086213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22281786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22281786 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12084605 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12084605 — Surrogate Endpoint (SUR): Blood pressure
Study 9470006 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9470006 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8592957 — Surrogate Endpoint (SUR): Bone mineral density
Study 2650517 — Surrogate Endpoint (SUR): Blood pressure
Study 31539075 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22987084 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2478340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14760265 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7970937 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7970937 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 28599212 — Surrogate Endpoint (SUR): Blood pressure
Study 24281285 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 20472597 — Surrogate Endpoint (SUR): Blood pressure
Study 10374215 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31706187 — Surrogate Endpoint (SUR): Blood pressure
Study 30816637 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19476985 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10597969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7015988 — Surrogate Endpoint (SUR): Blood pressure
Study 29223437 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 23759284 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12049015 — Surrogate Endpoint (SUR): Blood pressure