TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18609485 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20841418 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20841418 — Surrogate Endpoint (SUR): Blood pressure
Study 16606867 — Surrogate Endpoint (SUR): Blood pressure
Study 16606867 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12568834 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11342422 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 1721977 — Surrogate Endpoint (SUR): Blood pressure
Study 2525329 — Surrogate Endpoint (SUR): Blood pressure
Study 28662448 — Surrogate Endpoint (SUR): Blood pressure
Study 22610748 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19877104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10624970 — Surrogate Endpoint (SUR): Blood pressure
Study 1569602 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 1569602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1569602 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 1569602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1569602 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 18580887 — Surrogate Endpoint (SUR): Blood pressure
Study 16176119 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16176119 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 28291552 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 25769303 — Surrogate Endpoint (SUR): Bone mineral density
Study 21497767 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 11192231 — Surrogate Endpoint (SUR): Blood pressure
Study 22437088 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22437088 — Surrogate Endpoint (SUR): Blood pressure
Study 18786316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18786316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18786316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6436633 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8590530 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26461465 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15465451 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 11219471 — Surrogate Endpoint (SUR): Blood pressure
Study 16490581 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10769552 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22715865 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 20185746 — Surrogate Endpoint (SUR): Blood pressure
Study 18705531 — Surrogate Endpoint (SUR): Blood pressure
Study 12518369 — Surrogate Endpoint (SUR): Serum creatinine
Study 31175716 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29215806 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 23127292 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23127292 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25385719 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 25385719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16685221 — Surrogate Endpoint (SUR): Blood pressure
Study 18929283 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15879168 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 12410458 — Safety Biomarker (SAF): Hyaluronic acid
Study 2646895 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29072162 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23462537 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30221194 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 22472173 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22472173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7552929 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28375035 — Surrogate Endpoint (SUR): Blood pressure
Study 19717185 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 18003960 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9557929 — Surrogate Endpoint (SUR): Blood pressure
Study 9557929 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2656775 — Surrogate Endpoint (SUR): Blood pressure
Study 31453723 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 19204207 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19204207 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 2677375 — Surrogate Endpoint (SUR): Blood pressure
Study 23676630 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study 10847665 — Surrogate Endpoint (SUR): Blood pressure
Study 7475056 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7475056 — Surrogate Endpoint (SUR): Blood pressure
Study 7475056 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29696643 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7605757 — Surrogate Endpoint (SUR): Blood pressure
Study 21178763 — Surrogate Endpoint (SUR): Blood pressure
Study 16469151 — Surrogate Endpoint (SUR): Blood pressure
Study 25997544 — Surrogate Endpoint (SUR): Serum uric acid
Study 11522112 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11522112 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25885409 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25885409 — Surrogate Endpoint (SUR): Serum creatinine
Study 24218874 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24218874 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15475831 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15475831 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2150644 — Surrogate Endpoint (SUR): Blood pressure
Study 11529630 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 9332682 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11717595 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31169350 — Surrogate Endpoint (SUR): Blood pressure
Study 17225548 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9695642 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 24184996 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19397392 — Surrogate Endpoint (SUR): Blood pressure
Study 19397392 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19397392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19397392 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15304040 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 15304040 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 15304040 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15304040 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15304040 — Safety Biomarker (SAF): Interleukin 1
Study 2696658 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15978304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15978304 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15978304 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10369648 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1532551 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1532551 — Surrogate Endpoint (SUR): Blood pressure
Study 2984332 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22819432 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22819432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7576933 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7576933 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30474700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7821310 — Safety Biomarker (SAF): L-acetylcarnitine
Study 29098259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1751665 — Surrogate Endpoint (SUR): Serum creatinine
Study 1751665 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 312708 — Surrogate Endpoint (SUR): Blood pressure
Study 27768857 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 27768857 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 3175393 — Surrogate Endpoint (SUR): Blood pressure
Study 30987269 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30987269 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 23283526 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31697384 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17144438 — Surrogate Endpoint (SUR): Blood pressure
Study 10731530 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2410328 — Monitoring Biomarker (MOI): HBV DNA
Study 30531676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26926681 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24621807 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22357725 — Surrogate Endpoint (SUR): Blood pressure
Study 18473409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18473409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18473409 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 18473409 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15723220 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8782129 — Surrogate Endpoint (SUR): Bone mineral density
Study 27178983 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16253099 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 24444353 — Monitoring Biomarker (MOI): HBV DNA
Study 29121401 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 29121401 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 29231508 — Surrogate Endpoint (SUR): Blood pressure
Study 20436711 — Monitoring Biomarker (MOI): HBV DNA
Study 18486741 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 22370739 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17851565 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 17851565 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 15681300 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8895264 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2049684 — Surrogate Endpoint (SUR): Blood pressure
Study 23651713 — Surrogate Endpoint (SUR): Blood pressure
Study 25284808 — Surrogate Endpoint (SUR): Serum creatinine
Study 21518967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12679925 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8992906 — Surrogate Endpoint (SUR): Blood pressure
Study 2943685 — Surrogate Endpoint (SUR): Blood pressure
Study 2943685 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29133606 — Surrogate Endpoint (SUR): Blood pressure
Study 29133606 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29133606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22386831 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 20299258 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 23809982 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 8243427 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18606533 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10670117 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 22180344 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 20431612 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 17962233 — Surrogate Endpoint (SUR): Blood pressure
Study 10516349 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29423410 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3922503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16816766 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 25489410 — Surrogate Endpoint (SUR): Blood pressure
Study 20508468 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 18569019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18569019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18569019 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16055779 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30609212 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18086944 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18086944 — Surrogate Endpoint (SUR): Blood pressure
Study 7795837 — Surrogate Endpoint (SUR): Blood pressure
Study 28235249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21317198 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 17878421 — Surrogate Endpoint (SUR): Blood pressure
Study 7653444 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7653444 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24641096 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15083372 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 7719523 — Surrogate Endpoint (SUR): Blood pressure
Study 7995674 — Predictive Biomarker (PRD): SMC3 mRNA
Genes: SMC3; BAM; BMH; CSPG6; SMC3L1
Study 14997962 — Surrogate Endpoint (SUR): Blood pressure
Study 10849526 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10849526 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10849526 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10849526 — Surrogate Endpoint (SUR): Serum creatinine
Study 8210613 — Surrogate Endpoint (SUR): Blood pressure
Study 26082887 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 20881606 — Surrogate Endpoint (SUR): Blood pressure
Study 15940143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15940143 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15940143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25123988 — Surrogate Endpoint (SUR): Serum testosterone
Study 22044402 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 21039313 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study 21039313 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23896353 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 19526040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19526040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19526040 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11590675 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27506742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27506742 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 14643271 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27466699 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 27466699 — Predictive Biomarker (PRD): CISH mRNA
Genes: CISH; G18
Study 27466699 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27466699 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 22161686 — Surrogate Endpoint (SUR): Bone mineral density
Study 20061334 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 7803596 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 8586009 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8586009 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1967533 — Surrogate Endpoint (SUR): Blood pressure
Study 27128565 — Surrogate Endpoint (SUR): Blood pressure
Study 19541578 — Surrogate Endpoint (SUR): Serum creatinine
Study 19541578 — Surrogate Endpoint (SUR): Blood pressure
Study 8117174 — Surrogate Endpoint (SUR): Blood pressure
Study 15675430 — Surrogate Endpoint (SUR): Blood pressure
Study 9658726 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28041830 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 24283136 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21150784 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11548842 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8279691 — Surrogate Endpoint (SUR): Blood pressure
Study 3495151 — Surrogate Endpoint (SUR): Blood pressure
Study 30514319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30514319 — Monitoring Biomarker (MOI): Procalcitonin
Study 20798196 — Predictive Biomarker (PRD): Hormone receptor
Study 15721728 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11910657 — Surrogate Endpoint (SUR): Bone mineral density
Study 24965700 — Surrogate Endpoint (SUR): Blood pressure
Study 26122230 — Surrogate Endpoint (SUR): Blood pressure
Study 20652275 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20652275 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20652275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20652275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20652275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18988907 — Surrogate Endpoint (SUR): Blood pressure
Study 9075853 — Surrogate Endpoint (SUR): Serum creatinine
Study 9075853 — Surrogate Endpoint (SUR): Blood pressure
Study 9505980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2860041 — Surrogate Endpoint (SUR): Blood pressure
Study 30589035 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27389564 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19713952 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19713952 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9846013 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 9846013 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 9846013 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 9846013 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1071702 — Surrogate Endpoint (SUR): Blood pressure
Study 29141164 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 23992877 — Predictive Biomarker (PRD): KCNK3 mRNA
Genes: KCNK3; TASK; TASK1
Study 23992877 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17021714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17021714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15104559 — Surrogate Endpoint (SUR): Bone mineral density
Study 2899719 — Monitoring Biomarker (MOI): HBV DNA
Study 31784746 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31784746 — Predictive Biomarker (PRD): CADPS mRNA
Genes: CADPS; CAPS; CAPS1; KIAA1121
Study 12297167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7847429 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2111981 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341