TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10523328 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10523328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9333110 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26657657 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26657657 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 24614125 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 24614125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24614125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24614125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18190629 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 11305719 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 20586997 — Surrogate Endpoint (SUR): Blood pressure
Study 823950 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 25989154 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23815739 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 18931330 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3039831 — Surrogate Endpoint (SUR): Blood pressure
Study 10949003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19490266 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24875804 — Surrogate Endpoint (SUR): Blood pressure
Study 24875804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20492837 — Surrogate Endpoint (SUR): Blood pressure
Study 3263508 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24411642 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 22801017 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 11341338 — Surrogate Endpoint (SUR): Bone mineral density
Study 9760814 — Surrogate Endpoint (SUR): Serum creatinine
Study 27568890 — Surrogate Endpoint (SUR): Blood pressure
Study 21560476 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19702080 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16814691 — Predictive Biomarker (PRD): DEFA1 mRNA
Genes: DEFA1; DEF1; DEFA2; MRS; DEFA1B
Study 28608311 — Surrogate Endpoint (SUR): Serum creatinine
Study 28608311 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23808786 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 21258075 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 18192895 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 18192895 — Safety Biomarker (SAF): DRD2
Study 23818718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19339957 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7515644 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2960473 — Surrogate Endpoint (SUR): Blood pressure
Study 25914018 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 28683357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28683357 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21436683 — Surrogate Endpoint (SUR): Blood pressure
Study 8793575 — Surrogate Endpoint (SUR): Serum creatinine
Study 20739874 — Surrogate Endpoint (SUR): Blood pressure
Study 20739874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20739874 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20739874 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20739874 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16099892 — Surrogate Endpoint (SUR): Blood pressure
Study 31196016 — Predictive Biomarker (PRD): Mitochondrial n-acetylglutamate synthase
Genes: NAGS
Study 28926579 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21071558 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21071558 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 18536953 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 11797178 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30354751 — Surrogate Endpoint (SUR): Blood pressure
Study 31253441 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31253441 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27760066 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17466722 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 15682349 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11737740 — Surrogate Endpoint (SUR): Blood pressure
Study 11737740 — Surrogate Endpoint (SUR): Serum potassium
Study 12959320 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 12959320 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 12959320 — Surrogate Endpoint (SUR): Blood pressure
Study 2827471 — Surrogate Endpoint (SUR): Blood pressure
Study 25015066 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25015066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15957693 — Surrogate Endpoint (SUR): Blood pressure
Study 10367599 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10367599 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7564346 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7564346 — Surrogate Endpoint (SUR): Blood pressure
Study 27143273 — Surrogate Endpoint (SUR): Blood pressure
Study 22433279 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15562127 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15562127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15562127 — Surrogate Endpoint (SUR): Blood pressure
Study 7875148 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23361871 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23361871 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19565135 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12624706 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7852747 — Surrogate Endpoint (SUR): Blood pressure
Study 7852747 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30240132 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28790038 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18574688 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 18574688 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 11922398 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9517631 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16500952 — Surrogate Endpoint (SUR): Blood pressure
Study 1788456 — Surrogate Endpoint (SUR): Blood pressure
Study 19404314 — Surrogate Endpoint (SUR): Blood pressure
Study 22435740 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8568290 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30516102 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27381232 — Surrogate Endpoint (SUR): Blood pressure
Study 23000523 — Predictive Biomarker (PRD): CLSTN3 mRNA
Genes: CLSTN3; CS3; KIAA0726
Study 12188097 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22398243 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22398243 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22398243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20104460 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9594511 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2687357 — Surrogate Endpoint (SUR): Blood pressure
Study 30188220 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22836073 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22836073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22836073 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7860392 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 7860392 — Predictive Biomarker (PRD): TIMM8A mRNA
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 7860392 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 7860392 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 26864458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17531335 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 373836 — Surrogate Endpoint (SUR): Blood pressure
Study 20616218 — Predictive Biomarker (PRD): CDKN2C mRNA
Genes: CDKN2C; CDKN6
Study 20616218 — Predictive Biomarker (PRD): ANP32E mRNA
Genes: ANP32E
Study 20616218 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 31886280 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26514001 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 26514001 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16614398 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 14714357 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 14714357 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1920184 — Surrogate Endpoint (SUR): Blood pressure
Study 23289958 — Surrogate Endpoint (SUR): Sperm parameters
Study 23289958 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2689046 — Surrogate Endpoint (SUR): Blood pressure
Study 26369324 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 22236208 — Predictive Biomarker (PRD): SLA mRNA
Genes: SLA; SLAP; SLAP1
Study 24504804 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 24504804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24504804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16129815 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19890073 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 27135916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27135916 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19234829 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19234829 — Surrogate Endpoint (SUR): Blood pressure
Study 15277416 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16647628 — Surrogate Endpoint (SUR): Blood pressure
Study 16307657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12114351 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 25367713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23559420 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15173081 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15173081 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 15173081 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 31234904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19661836 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 19661836 — Predictive Biomarker (PRD): MUC2 mRNA
Genes: MUC2; SMUC
Study 19661836 — Predictive Biomarker (PRD): MUC4 mRNA
Genes: MUC4
Study 19661836 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 19661836 — Predictive Biomarker (PRD): MUC13 mRNA
Genes: MUC13; DRCC1; RECC; UNQ6194/PRO20221
Study 19661836 — Predictive Biomarker (PRD): MUC15 mRNA
Genes: MUC15; UNQ750/PRO1481
Study 19661836 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 19661836 — Predictive Biomarker (PRD): MUC17 mRNA
Genes: MUC17; MUC3
Study 9754586 — Surrogate Endpoint (SUR): Blood pressure
Study 7918729 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 11950484 — Surrogate Endpoint (SUR): Blood pressure
Study 28724331 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28724331 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24424409 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17138937 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9031498 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 2965231 — Surrogate Endpoint (SUR): Blood pressure
Study 12221873 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2266681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2266681 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 25312315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1279289 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1279289 — Surrogate Endpoint (SUR): Blood pressure
Study 4018101 — Surrogate Endpoint (SUR): Serum calcium
Study 30706247 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30706247 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 30706247 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 30706247 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 7536068 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7536068 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27077348 — Surrogate Endpoint (SUR): Blood pressure
Study 18752682 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 2094375 — Predictive Biomarker (PRD): TEP1 mRNA
Genes: TEP1; TLP1; TP1
Study 23000726 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 1430130 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3908501 — Surrogate Endpoint (SUR): Blood pressure
Study 28741804 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17133559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17133559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9545899 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 28903131 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 15025222 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 8624429 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 31733926 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 21074790 — Surrogate Endpoint (SUR): Serum sodium
Study 9127923 — Surrogate Endpoint (SUR): Blood pressure
Study 9211675 — Surrogate Endpoint (SUR): Blood pressure
Study 2973171 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25956949 — Surrogate Endpoint (SUR): Blood pressure
Study 25956949 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25956949 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 12657164 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12657164 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study 12657164 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study 12657164 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10933368 — Surrogate Endpoint (SUR): Serum creatinine
Study 2169702 — Surrogate Endpoint (SUR): Blood pressure
Study 2169702 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2169702 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23949025 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15175560 — Surrogate Endpoint (SUR): Blood pressure
Study 27966225 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31731885 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31731885 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 31731885 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 31731885 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study 31731885 — Predictive Biomarker (PRD): Hepatitis A virus cellular receptor 2
Genes: HAVCR2; TIM3; TIMD3
Study 19419253 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17713154 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17713154 — Monitoring Biomarker (MOI): HBV DNA
Study 12521783 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17560080 — Surrogate Endpoint (SUR): Blood pressure
Study 11600531 — Surrogate Endpoint (SUR): Bone mineral density
Study 9682807 — Surrogate Endpoint (SUR): Blood pressure
Study 19336453 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17353499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15115860 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 29622380 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 8695028 — Surrogate Endpoint (SUR): Blood pressure
Study 29119275 — Surrogate Endpoint (SUR): Blood pressure
Study 15758622 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 6352185 — Surrogate Endpoint (SUR): Blood pressure
Study 26909960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26909960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26909960 — Surrogate Endpoint (SUR): Serum creatinine
Study 22382219 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22382219 — Surrogate Endpoint (SUR): Serum creatinine
Study 30802822 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30802822 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9642936 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 2576861 — Predictive Biomarker (PRD): EHF mRNA
Genes: EHF; ESE3; ESE3B; ESEJ
Study 26456573 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26456573 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28895428 — Surrogate Endpoint (SUR): Bone mineral density
Study 7975797 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30054906 — Surrogate Endpoint (SUR): Serum creatinine
Study 25952653 — Surrogate Endpoint (SUR): Blood pressure
Study 23657490 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 21720260 — Surrogate Endpoint (SUR): Blood pressure
Study 19595382 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 19595382 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28251937 — Surrogate Endpoint (SUR): Blood pressure
Study 25546444 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 14991374 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14991374 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 14991374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31619463 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 23197664 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23197664 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18957532 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15531767 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15531767 — Surrogate Endpoint (SUR): Blood pressure
Study 3550555 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 3550555 — Predictive Biomarker (PRD): RARB mRNA
Genes: RARB; HAP; NR1B2
Study 15829527 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 7554523 — Surrogate Endpoint (SUR): Serum creatinine
Study 7554523 — Surrogate Endpoint (SUR): Blood pressure
Study 21973199 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21973199 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10838741 — Surrogate Endpoint (SUR): Serum creatinine
Study 8754325 — Surrogate Endpoint (SUR): Blood pressure
Study 11545760 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11545760 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9568701 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9568701 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 3399521 — Surrogate Endpoint (SUR): Blood pressure
Study 19225403 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16782098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16782098 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29760284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25736389 — Surrogate Endpoint (SUR): Blood pressure
Study 22784975 — Surrogate Endpoint (SUR): Blood pressure