TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12056708 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 30542740 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 30542740 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 24647863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24647863 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16053010 — Safety Biomarker (SAF): MTHFR
Study 11812753 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 29925934 — Predictive Biomarker (PRD): VEGFC mRNA
Genes: VEGFC
Study 29925934 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 29925934 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24613084 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 24613084 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 22191384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12826150 — Surrogate Endpoint (SUR): Serum creatinine
Study 29649997 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 27646843 — Predictive Biomarker (PRD): HDAC6 mRNA
Genes: HDAC6; KIAA0901; JM21
Study 19893505 — Surrogate Endpoint (SUR): Blood pressure
Study 18570844 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 26193215 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23273975 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 19906561 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 14763958 — Surrogate Endpoint (SUR): Blood pressure
Study 2682243 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2682243 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24348029 — Surrogate Endpoint (SUR): Bone mineral density
Study 27765184 — Surrogate Endpoint (SUR): Blood pressure
Study 22576032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22576032 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22576032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22576032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22576032 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8650026 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 2169638 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 24126178 — Surrogate Endpoint (SUR): Blood pressure
Study 12445026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8551488 — Surrogate Endpoint (SUR): Blood pressure
Study 30413516 — Surrogate Endpoint (SUR): Blood pressure
Study 21173378 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21173378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21173378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21173378 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9637644 — Surrogate Endpoint (SUR): Blood pressure
Study 26329749 — Monitoring Biomarker (MOI): HBV DNA
Study 9188109 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21986350 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15233305 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 20122848 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20122848 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20122848 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20122848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8542050 — Surrogate Endpoint (SUR): Blood pressure
Study 8542050 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8542050 — Surrogate Endpoint (SUR): Serum potassium
Study 6338682 — Surrogate Endpoint (SUR): Blood pressure
Study 31471378 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 31471378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31471378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31471378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17080429 — Safety Biomarker (SAF): Reactive oxygen species
Study 17080429 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 15604946 — Safety Biomarker (SAF): DRD2
Study 9458917 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9156817 — Surrogate Endpoint (SUR): Serum creatinine
Study 9140802 — Surrogate Endpoint (SUR): Blood pressure
Study 29176391 — Surrogate Endpoint (SUR): Blood pressure
Study 16817817 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16817817 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 31122211 — Surrogate Endpoint (SUR): Blood pressure
Study 22352336 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7672157 — Safety Biomarker (SAF): Reactive oxygen species
Study 21255134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2681451 — Surrogate Endpoint (SUR): Blood pressure
Study 9327783 — Predictive Biomarker (PRD): MPG mRNA
Genes: MPG; AAG; ANPG; MID1
Study 27105046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22337533 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 16896862 — Surrogate Endpoint (SUR): Blood pressure
Study 9282827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28543183 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15462105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15462105 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15462105 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11737509 — Surrogate Endpoint (SUR): Bacterial count
Study 20590606 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 18380893 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18380893 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18380893 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18380893 — Predictive Biomarker (PRD): Hormone receptor
Study 16644314 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16644314 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9121826 — Surrogate Endpoint (SUR): Blood pressure
Study 2003657 — Surrogate Endpoint (SUR): Blood pressure
Study 24956862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24956862 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 24956862 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 20594555 — Surrogate Endpoint (SUR): Blood pressure
Study 20594555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6630968 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28560658 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 28560658 — Predictive Biomarker (PRD): SLC38A3 mRNA
Genes: SLC38A3; G17; NAT1; SN1; SNAT3
Study 28560658 — Predictive Biomarker (PRD): CYP2F1 mRNA
Genes: CYP2F1
Study 28560658 — Predictive Biomarker (PRD): ORM2 mRNA
Genes: ORM2; AGP2
Study 17550998 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15047641 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 15047641 — Surrogate Endpoint (SUR): Serum creatinine
Study 24515307 — Surrogate Endpoint (SUR): Serum creatinine
Study 1442579 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1442579 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30795775 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30795775 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29106031 — Surrogate Endpoint (SUR): Blood pressure
Study 19329404 — Surrogate Endpoint (SUR): Blood pressure
Study 15987917 — Monitoring Biomarker (MOI): HBV DNA
Study 12814993 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10585039 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 10585039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10585039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10585039 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 1708046 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1708046 — Surrogate Endpoint (SUR): Blood pressure
Study 25890367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23711618 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21825112 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 7511751 — Surrogate Endpoint (SUR): Blood pressure
Study 7511751 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27854117 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27854117 — Surrogate Endpoint (SUR): Blood pressure
Study 15009104 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15009104 — Predictive Biomarker (PRD): KLRD1 mRNA
Genes: KLRD1; CD94
Study 15009104 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 15009104 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 29360920 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 27192695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19205092 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19205092 — Surrogate Endpoint (SUR): Blood pressure
Study 11889276 — Surrogate Endpoint (SUR): Blood pressure
Study 31254422 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28031175 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28031175 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28031175 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 22591260 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21367933 — Surrogate Endpoint (SUR): Bone mineral density
Study 19952754 — Surrogate Endpoint (SUR): Blood pressure
Study 16134183 — Surrogate Endpoint (SUR): Serum calcium
Study 1533167 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25154822 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26652987 — Surrogate Endpoint (SUR): Blood pressure
Study 17699280 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17699280 — Surrogate Endpoint (SUR): Serum creatinine
Study 10624998 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10624998 — Surrogate Endpoint (SUR): Blood pressure
Study 15472494 — Surrogate Endpoint (SUR): Blood pressure
Study 12814852 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8933997 — Surrogate Endpoint (SUR): Blood pressure
Study 15534554 — Surrogate Endpoint (SUR): Blood pressure
Study 11730651 — Surrogate Endpoint (SUR): Blood pressure
Study 11907915 — Surrogate Endpoint (SUR): Bone mineral density
Study 25982826 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 8276048 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3440636 — Surrogate Endpoint (SUR): Blood pressure
Study 29444393 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 22778122 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21610123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12201618 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 24749682 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19961017 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 19961017 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19961017 — Surrogate Endpoint (SUR): Blood pressure
Study 17980419 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 16202012 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29052559 — Surrogate Endpoint (SUR): Serum creatinine
Study 19137409 — Surrogate Endpoint (SUR): Serum creatinine
Study 19137409 — Surrogate Endpoint (SUR): Serum potassium
Study 17507633 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9595988 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 2539017 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2539017 — Surrogate Endpoint (SUR): Blood pressure
Study 28986515 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 11870242 — Surrogate Endpoint (SUR): Bone mineral density
Study 7850984 — Surrogate Endpoint (SUR): Blood pressure
Study 23404180 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 23404180 — Surrogate Endpoint (SUR): Blood pressure
Study 20506328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17239942 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 7992096 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21209411 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 16403776 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 16403776 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28713486 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 28713486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9560030 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22690080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15625256 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 18799080 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 18799080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10656435 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 3777409 — Surrogate Endpoint (SUR): Blood pressure
Study 29183872 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 29183872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29183872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29183872 — Surrogate Endpoint (SUR): Serum testosterone
Study 11336590 — Surrogate Endpoint (SUR): Blood pressure
Study 25566749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8090093 — Surrogate Endpoint (SUR): Blood pressure
Study 30042065 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30042065 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30042065 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study 30042065 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study 30042065 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 30042065 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 30042065 — Predictive Biomarker (PRD): Microsatellite instability
Study 27299514 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 23034468 — Surrogate Endpoint (SUR): Blood pressure
Study 15205218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15205218 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15205218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11315238 — Surrogate Endpoint (SUR): Bone mineral density
Study 7817530 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 26060295 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26060295 — Surrogate Endpoint (SUR): Bone mineral density
Study 16675499 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 15517300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15517300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26024678 — Surrogate Endpoint (SUR): Bone mineral density
Study 6394350 — Surrogate Endpoint (SUR): Blood pressure
Study 26682971 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 24846355 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 24846355 — Surrogate Endpoint (SUR): Blood pressure
Study 21293446 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21293446 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18423812 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18423812 — Surrogate Endpoint (SUR): Blood pressure
Study 18423812 — Surrogate Endpoint (SUR): Serum creatinine
Study 801570 — Surrogate Endpoint (SUR): Blood pressure
Study 31195706 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 28170396 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23767174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21923601 — Surrogate Endpoint (SUR): Blood pressure
Study 8686202 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15908621 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15908621 — Surrogate Endpoint (SUR): Blood pressure
Study 7492860 — Surrogate Endpoint (SUR): Bone mineral density
Study 7042111 — Surrogate Endpoint (SUR): Blood pressure
Study 11127567 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 3472452 — Surrogate Endpoint (SUR): Blood pressure
Study 30219886 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30219886 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 30219886 — Predictive Biomarker (PRD): Hormone receptor
Study 7656916 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28100321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28100321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21331628 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17056201 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 28642125 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 23392000 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 23392000 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study 16338907 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16338907 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9251847 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24477028 — Surrogate Endpoint (SUR): Blood pressure
Study 14571352 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12569689 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23219623 — Surrogate Endpoint (SUR): Bone mineral density
Study 8509640 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8509640 — Monitoring Biomarker (MOI): HBV DNA
Study 16855169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16855169 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 16855169 — Surrogate Endpoint (SUR): Bone mineral density
Study 11180916 — Surrogate Endpoint (SUR): Bone mineral density
Study 29863955 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29863955 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29863955 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29863955 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 17673094 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15750150 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26342738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21214631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19707226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4