TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21981870 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 12774010 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10669686 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 3125004 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26317782 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14626627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14626627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14626627 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 25730596 — Surrogate Endpoint (SUR): Bone mineral density
Study 18163485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16389028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14636465 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 1817902 — Surrogate Endpoint (SUR): Blood pressure
Study 31838256 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 9239583 — Surrogate Endpoint (SUR): Blood pressure
Study 29231606 — Surrogate Endpoint (SUR): Bone mineral density
Study 23630244 — Surrogate Endpoint (SUR): Blood pressure
Study 19729375 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12846539 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8973673 — Surrogate Endpoint (SUR): Serum testosterone
Study 29734180 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22217510 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 22217510 — Predictive Biomarker (PRD): IL13RA1 mRNA
Genes: IL13RA1; IL13R; IL13RA
Study 22217510 — Predictive Biomarker (PRD): TPST1 mRNA
Genes: TPST1
Study 22217510 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 20171140 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20171140 — Surrogate Endpoint (SUR): Blood pressure
Study 7572323 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 7572323 — Surrogate Endpoint (SUR): Bone mineral density
Study 2190885 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11895893 — Predictive Biomarker (PRD): Hormone receptor
Study 21945262 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18297973 — Surrogate Endpoint (SUR): Blood pressure
Study 14567768 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 387230 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 30630560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30630560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30630560 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 11978337 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18855271 — Surrogate Endpoint (SUR): Blood pressure
Study 8607241 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11515616 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11515616 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8167386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8167386 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23172272 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23172272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 799566 — Surrogate Endpoint (SUR): Blood pressure
Study 31893589 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 26048346 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 27746061 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14657693 — Surrogate Endpoint (SUR): Bone mineral density
Study 6757152 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 6757152 — Surrogate Endpoint (SUR): Blood pressure
Study 18167405 — Surrogate Endpoint (SUR): Serum testosterone
Study 18167405 — Surrogate Endpoint (SUR): Bone mineral density
Study 18167405 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17062431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12937992 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 12937992 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 9360514 — Predictive Biomarker (PRD): PRLR mRNA
Genes: PRLR
Study 28953494 — Surrogate Endpoint (SUR): Blood pressure
Study 26027555 — Surrogate Endpoint (SUR): Serum sodium
Study 16162034 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16162034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20668151 — Surrogate Endpoint (SUR): Blood pressure
Study 16899309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12166584 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12166584 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 8710426 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6667628 — Surrogate Endpoint (SUR): Blood pressure
Study 31587658 — Surrogate Endpoint (SUR): Blood pressure
Study 30640985 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30640985 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22258265 — Surrogate Endpoint (SUR): Bone mineral density
Study 20073463 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 12107236 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7735957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7735957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24439974 — Surrogate Endpoint (SUR): Blood pressure
Study 30594153 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 24518280 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 22997994 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 20678685 — Surrogate Endpoint (SUR): Blood pressure
Study 15735276 — Surrogate Endpoint (SUR): Blood pressure
Study 22333485 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22333485 — Surrogate Endpoint (SUR): Blood pressure
Study 22333485 — Surrogate Endpoint (SUR): Serum creatinine
Study 11957164 — Safety Biomarker (SAF): IL-6 and IL-10
Study 28820950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28820950 — Safety Biomarker (SAF): Reactive oxygen species
Study 28820950 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26337448 — Surrogate Endpoint (SUR): Blood pressure
Study 22710530 — Surrogate Endpoint (SUR): Blood pressure
Study 19552057 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19552057 — Surrogate Endpoint (SUR): Blood pressure
Study 21977250 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21977250 — Surrogate Endpoint (SUR): Blood pressure
Study 27555374 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21762224 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 21762224 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9862946 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8991823 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 8991823 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30943980 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28606441 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28606441 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28606441 — Surrogate Endpoint (SUR): Blood pressure
Study 15697056 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 12017347 — Surrogate Endpoint (SUR): Blood pressure
Study 15526237 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15526237 — Surrogate Endpoint (SUR): Blood pressure
Study 22436400 — Surrogate Endpoint (SUR): Bone mineral density
Study 16162943 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12578865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12578865 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 10319771 — Surrogate Endpoint (SUR): Serum sodium
Study 10319771 — Surrogate Endpoint (SUR): Serum potassium
Study 31816446 — Safety Biomarker (SAF): Interleukin 12
Study 31816446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9135928 — Surrogate Endpoint (SUR): Blood pressure
Study 29970059 — Surrogate Endpoint (SUR): Serum calcium
Study 24041914 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11899644 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 26827702 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PENK mRNA
Genes: PENK
Study 22527351 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22527351 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 17684125 — Predictive Biomarker (PRD): AMACR mRNA
Genes: AMACR
Study 28092973 — Predictive Biomarker (PRD): ADAMTS7 mRNA
Genes: ADAMTS7
Study 9486993 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9486993 — Surrogate Endpoint (SUR): Blood pressure
Study 2244564 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20298505 — Surrogate Endpoint (SUR): Blood pressure
Study 25925891 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 8147246 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26880227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20501489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20501489 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30762770 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30762770 — Safety Biomarker (SAF): BDNF
Study 30762770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28152332 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 15283821 — Surrogate Endpoint (SUR): Blood pressure
Study 11207468 — Surrogate Endpoint (SUR): Blood pressure
Study 15448121 — Surrogate Endpoint (SUR): Blood pressure
Study 9884318 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 24229754 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 14748768 — Predictive Biomarker (PRD): ACSL1 mRNA
Genes: ACSL1; FACL1; FACL2; LACS; LACS1; LACS2
Study 2865889 — Surrogate Endpoint (SUR): Blood pressure
Study 23149426 — Surrogate Endpoint (SUR): Blood pressure
Study 3839174 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24712573 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 2955979 — Surrogate Endpoint (SUR): Blood pressure
Study 22418044 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22418044 — Surrogate Endpoint (SUR): Serum creatinine
Study 25778333 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 9331924 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19595257 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 3579004 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 26717214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10750574 — Surrogate Endpoint (SUR): Bone mineral density
Study 31119206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2757896 — Surrogate Endpoint (SUR): Blood pressure
Study 14971964 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 11346705 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11346705 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9040797 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 7931444 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23945719 — Surrogate Endpoint (SUR): Blood pressure
Study 18299490 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2972159 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 25823909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10658682 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 10658682 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 2126727 — Surrogate Endpoint (SUR): Blood pressure
Study 25927716 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 14718679 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 11433128 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11433128 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 11433128 — Surrogate Endpoint (SUR): Blood pressure
Study 9773138 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19483278 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 19287303 — Surrogate Endpoint (SUR): Bone mineral density
Study 11165950 — Surrogate Endpoint (SUR): Serum calcium
Study 9708956 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8069001 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30736402 — Surrogate Endpoint (SUR): Blood pressure
Study 21321298 — Predictive Biomarker (PRD): Hormone receptor
Study 7512659 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31983236 — Surrogate Endpoint (SUR): Blood pressure
Study 31983236 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 31291514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25861013 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 25861013 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 21461325 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 11121913 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 3519237 — Surrogate Endpoint (SUR): Blood pressure
Study 8712196 — Surrogate Endpoint (SUR): Blood pressure
Study 30239650 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 30239650 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 22264573 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1691243 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28797349 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28797349 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24119112 — Surrogate Endpoint (SUR): Blood pressure
Study 19497571 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19497571 — Surrogate Endpoint (SUR): Blood pressure
Study 12359793 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 12359793 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9695133 — Surrogate Endpoint (SUR): Blood pressure
Study 873718 — Surrogate Endpoint (SUR): Blood pressure
Study 2700320 — Surrogate Endpoint (SUR): Blood pressure
Study 17607002 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 17607002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7884789 — Surrogate Endpoint (SUR): Blood pressure
Study 11465928 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 11465928 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9715439 — Surrogate Endpoint (SUR): Blood pressure
Study 2646896 — Surrogate Endpoint (SUR): Blood pressure
Study 19756505 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7589042 — Surrogate Endpoint (SUR): Blood pressure
Study 25796973 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 25796973 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 23815518 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23815518 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21837954 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 11264569 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 7839785 — Surrogate Endpoint (SUR): Blood pressure
Study 27296202 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 10396191 — Surrogate Endpoint (SUR): Blood pressure
Study 7027889 — Surrogate Endpoint (SUR): Blood pressure
Study 27786406 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 17003087 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 17003087 — Predictive Biomarker (PRD): Hormone receptor
Study 9375939 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9375939 — Surrogate Endpoint (SUR): Blood pressure
Study 26962236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26962236 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26962236 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 6639917 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31541874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31541874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11279634 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11279634 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 2540054 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2540054 — Surrogate Endpoint (SUR): Blood pressure
Study 989578 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30192802 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30192802 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 30192802 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 30192802 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 30192802 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 20398482 — Surrogate Endpoint (SUR): Blood pressure
Study 15880810 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 11689270 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28124536 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 19214143 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study 19214143 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study 19214143 — Predictive Biomarker (PRD): CYSLTR1 mRNA
Genes: CYSLTR1; CYSLT1
Study 19214143 — Predictive Biomarker (PRD): LTA4H mRNA
Genes: LTA4H; LTA4
Study 17264955 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 11409217 — Surrogate Endpoint (SUR): Blood pressure
Study 9493975 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15361745 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 2955717 — Predictive Biomarker (PRD): ANTXR1 mRNA
Genes: ANTXR1; ATR; TEM8
Study 2955717 — Predictive Biomarker (PRD): SDC1 mRNA
Genes: SDC1; SDC
Study 25861808 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 22326387 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 2184938 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2184938 — Surrogate Endpoint (SUR): Blood pressure
Study 31589776 — Surrogate Endpoint (SUR): Bone mineral density
Study 28390867 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1412152 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1412152 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 23725092 — Surrogate Endpoint (SUR): Blood pressure
Study 19959915 — Surrogate Endpoint (SUR): Bone mineral density
Study 15356403 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11438314 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11438314 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11438314 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28651648 — Safety Biomarker (SAF): Reactive oxygen species
Study 28651648 — Surrogate Endpoint (SUR): Serum creatinine
Study 23399476 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 14731120 — Monitoring Biomarker (MOI): HBV DNA
Study 11477496 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 31334703 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31334703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1