TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28113032 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25641570 — Monitoring Biomarker (MOI): HBV DNA
Study 31330524 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 29880276 — Surrogate Endpoint (SUR): Blood pressure
Study 27932335 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 15167314 — Surrogate Endpoint (SUR): Bone mineral density
Study 15167314 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 12851621 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10579117 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 10579117 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 8562413 — Predictive Biomarker (PRD): NCAM1 mRNA
Genes: NCAM1; NCAM
Study 8562413 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8562413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27505335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27505335 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20571306 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 16832679 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 14563899 — Predictive Biomarker (PRD): HTRA3 mRNA
Genes: HTRA3; PRSP
Study 24643403 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9697988 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25078387 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25078387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21057570 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21057570 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 3116996 — Surrogate Endpoint (SUR): Blood pressure
Study 27645350 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19939441 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16280438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11986916 — Surrogate Endpoint (SUR): Blood pressure
Study 29798253 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 19531217 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19531217 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7986979 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 21173013 — Safety Biomarker (SAF): Interleukin 1
Study 21173013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12563620 — Surrogate Endpoint (SUR): Serum creatinine
Study 18320015 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 17205816 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 17205816 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31655622 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17352866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17352866 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 23701010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31615177 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 27740732 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 27740732 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 27740732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STX1B mRNA
Genes: STX1B; STX1B1; STX1B2
Study 27740732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 23384679 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 23384679 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 14640133 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10780036 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1339211 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30730980 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22752636 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 22752636 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 22752636 — Predictive Biomarker (PRD): HTATIP2 mRNA
Genes: HTATIP2; CC3; TIP30
Study 22752636 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study 22752636 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18550198 — Surrogate Endpoint (SUR): Serum creatinine
Study 7150496 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29979882 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 29912955 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 7608279 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7608279 — Surrogate Endpoint (SUR): Blood pressure
Study 30999952 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 25935596 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 8972892 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8972892 — Surrogate Endpoint (SUR): Blood pressure
Study 6467836 — Surrogate Endpoint (SUR): Blood pressure
Study 17071931 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16267764 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16267764 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 16267764 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 16267764 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16267764 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 31830292 — Safety Biomarker (SAF): Hyaluronic acid
Study 11430565 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11430565 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 7968645 — Surrogate Endpoint (SUR): Bone mineral density
Study 26184525 — Safety Biomarker (SAF): Interleukin 1
Study 17004900 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6748177 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6748177 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29961562 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 26278425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26278425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26278425 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 26278425 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 26278425 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 10826509 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 24331154 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 16120857 — Surrogate Endpoint (SUR): Blood pressure
Study 9108791 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3479012 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 28890996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27356786 — Surrogate Endpoint (SUR): Blood pressure
Study 21503940 — Monitoring Biomarker (MOI): HBV DNA
Study 12930422 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18833043 — Safety Biomarker (SAF): Hyaluronic acid
Study 16186422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16186422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16186422 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 2459540 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2459540 — Surrogate Endpoint (SUR): Blood pressure
Study 27059056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16612259 — Surrogate Endpoint (SUR): Blood pressure
Study 12759717 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8678327 — Surrogate Endpoint (SUR): Blood pressure
Study 11742909 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19038698 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 19038698 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20007824 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 20007824 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 2140375 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 7322956 — Surrogate Endpoint (SUR): Blood pressure
Study 22836303 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 22836303 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 371036 — Surrogate Endpoint (SUR): Blood pressure
Study 15354030 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 15354030 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15354030 — Surrogate Endpoint (SUR): Serum testosterone
Study 10740332 — Surrogate Endpoint (SUR): Bone mineral density
Study 12942707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12942707 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study 16880426 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7534423 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 23906899 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 10945312 — Surrogate Endpoint (SUR): Blood pressure
Study 22995653 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10391666 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10391666 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 19436684 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 19436684 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17564015 — Surrogate Endpoint (SUR): Blood pressure
Study 17564015 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14757271 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 14757271 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8163718 — Surrogate Endpoint (SUR): Blood pressure
Study 27488071 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22781292 — Surrogate Endpoint (SUR): Pathological complete response
Study 8796367 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8796367 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 31543976 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27760089 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 22333882 — Surrogate Endpoint (SUR): Blood pressure
Study 12943623 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8856711 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 29133522 — Surrogate Endpoint (SUR): Blood pressure
Study 23436264 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20578162 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30829023 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22932122 — Surrogate Endpoint (SUR): Serum sodium
Study 22932122 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26021829 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26021829 — Surrogate Endpoint (SUR): Serum creatinine
Study 19651921 — Surrogate Endpoint (SUR): Blood pressure
Study 9658370 — Monitoring Biomarker (MOI): HBV DNA
Study 25587056 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23827726 — Safety Biomarker (SAF): APC
Genes: DP2; DP3; DP2.5; PPP1R46
Study 15526717 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 15526717 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9210503 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29533726 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 25229735 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 25229735 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 22739979 — Surrogate Endpoint (SUR): Blood pressure
Study 19617657 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 807698 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 25800753 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23691002 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 15166532 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11479154 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11479154 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11479154 — Safety Biomarker (SAF): Interleukin 12
Study 30536648 — Surrogate Endpoint (SUR): Blood pressure
Study 25015215 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 22311988 — Surrogate Endpoint (SUR): Blood pressure
Study 22302014 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16324236 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 12196359 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7616027 — Safety Biomarker (SAF): Interleukin 1
Study 7616027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31168657 — Surrogate Endpoint (SUR): Bone mineral density
Study 23430010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23430010 — Surrogate Endpoint (SUR): Blood pressure
Study 23430010 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9892479 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31816818 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25006707 — Surrogate Endpoint (SUR): Blood pressure
Study 10099910 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25483419 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 25483419 — Surrogate Endpoint (SUR): Blood pressure
Study 18332608 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18332608 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11127852 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 11127852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11127852 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22186694 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 7617237 — Surrogate Endpoint (SUR): Blood pressure
Study 12039487 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 12039487 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26521569 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 16897661 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28872917 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25044423 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21542122 — Surrogate Endpoint (SUR): Serum creatinine
Study 21542122 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 7959083 — Surrogate Endpoint (SUR): Blood pressure
Study 8880110 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26448506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26448506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23897038 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 23897038 — Predictive Biomarker (PRD): HTR3A mRNA
Genes: HTR3A; 5HT3R; HTR3
Study 8623947 — Surrogate Endpoint (SUR): Serum creatinine
Study 1496838 — Surrogate Endpoint (SUR): Blood pressure
Study 6648053 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16635963 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7297020 — Surrogate Endpoint (SUR): Blood pressure
Study 25413958 — Surrogate Endpoint (SUR): Blood pressure
Study 12869355 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 1958561 — Surrogate Endpoint (SUR): Serum testosterone
Study 6765140 — Surrogate Endpoint (SUR): Blood pressure
Study 30704260 — Surrogate Endpoint (SUR): Blood pressure
Study 19217745 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16930803 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 16501636 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10992963 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 10992963 — Surrogate Endpoint (SUR): Blood pressure
Study 1510446 — Surrogate Endpoint (SUR): Serum creatinine
Study 6649721 — Surrogate Endpoint (SUR): Blood pressure
Study 24947080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 22958958 — Surrogate Endpoint (SUR): Blood pressure
Study 9454384 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8216397 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3688417 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28028918 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22954201 — Surrogate Endpoint (SUR): Blood pressure
Study 21680153 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 8692536 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 21190603 — Surrogate Endpoint (SUR): Serum creatinine
Study 16823067 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8923073 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2936354 — Surrogate Endpoint (SUR): Blood pressure
Study 22721929 — Surrogate Endpoint (SUR): Serum creatinine
Study 18283621 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 10525140 — Surrogate Endpoint (SUR): Blood pressure
Study 7725888 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7725888 — Surrogate Endpoint (SUR): Blood pressure
Study 27736246 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23982033 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17552955 — Surrogate Endpoint (SUR): Bone mineral density
Study 2184649 — Surrogate Endpoint (SUR): Blood pressure
Study 17598652 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30966831 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 27751214 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 25732262 — Safety Biomarker (SAF): Hyaluronic acid
Study 16148617 — Surrogate Endpoint (SUR): Blood pressure
Study 2347325 — Surrogate Endpoint (SUR): Blood pressure
Study 9931168 — Surrogate Endpoint (SUR): Blood pressure
Study 28455465 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 26075212 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26075212 — Safety Biomarker (SAF): BDNF
Study 10726720 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10726720 — Surrogate Endpoint (SUR): Blood pressure
Study 1550016 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1550016 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15964292 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 11834427 — Surrogate Endpoint (SUR): Bone mineral density
Study 9289452 — Surrogate Endpoint (SUR): Blood pressure
Study 6499703 — Surrogate Endpoint (SUR): Serum potassium
Study 16257098 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 16257098 — Predictive Biomarker (PRD): CLSTN1 mRNA
Genes: CLSTN1; CS1; KIAA0911
Study 16257098 — Predictive Biomarker (PRD): CLSTN2 mRNA
Genes: CLSTN2; CS2
Study 11102253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9285660 — Surrogate Endpoint (SUR): Blood pressure
Study 8301153 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31882375 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31882375 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7516915 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7516915 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30317947 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30317947 — Surrogate Endpoint (SUR): Serum creatinine
Study 25758041 — Surrogate Endpoint (SUR): Blood pressure
Study 22205355 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study 22205355 — Surrogate Endpoint (SUR): Total kidney volume
Study 9233976 — Surrogate Endpoint (SUR): Blood pressure
Study 9233976 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28681388 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22733406 — Safety Biomarker (SAF): IL-6 and IL-10
Study 9683300 — Surrogate Endpoint (SUR): Bone mineral density
Study 30586732 — Surrogate Endpoint (SUR): Blood pressure
Study 23761104 — Predictive Biomarker (PRD): TAS1R3 mRNA
Genes: TAS1R3; T1R3; TR3
Study 23761104 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study 19407949 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 16529161 — Safety Biomarker (SAF): Reactive oxygen species
Study 11387733 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 3914313 — Surrogate Endpoint (SUR): Blood pressure
Study 12730120 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 10774461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10774461 — Safety Biomarker (SAF): Interleukin 1
Study 21524314 — Surrogate Endpoint (SUR): Blood pressure
Study 26686053 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 26686053 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study 22581647 — Surrogate Endpoint (SUR): Bone mineral density
Study 10196011 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 10196011 — Surrogate Endpoint (SUR): Serum calcium