TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03640429 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01724528 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT04370119 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04040777 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05153057 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01761240 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT00757029 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study NCT00757029 — Predictive Biomarker (PRD): NE
Study NCT01696448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04193059 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04193059 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04193059 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04193059 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01538238 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT01538238 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01538238 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04257760 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00171860 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT02727426 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04521049 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT01099787 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT00004260 — Safety Biomarker (SAF): Interleukin 12
Study NCT02200640 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01580501 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01580501 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04371393 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04371393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00137891 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04435717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04588324 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT04588324 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT02369172 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT00691548 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02284295 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study NCT02284295 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study NCT02284295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02284295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02284295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01583621 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03801044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03645434 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT00082823 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01317680 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT00493077 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02484170 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT02933905 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02933905 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01590888 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00696917 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT00001357 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00430638 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02052492 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02052492 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT02707822 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT02707822 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02707822 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT02707822 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study NCT02304198 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00122980 — Predictive Biomarker (PRD): Liver iron
Study NCT02228837 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02228837 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT02228837 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02013843 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00935922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00935922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02139592 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00788177 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01121809 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT04527198 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01980472 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01385020 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01894204 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03515629 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01433744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03472560 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03472560 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01374503 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT01777152 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT03859583 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03581851 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03581851 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02652884 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01707407 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01707407 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01175941 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03578952 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04385563 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00969722 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00145457 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT05356754 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00317889 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01652469 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04592783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04336501 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04246983 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00004809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01009879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00232726 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT00742144 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03214484 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04335019 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01898117 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02453204 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04119518 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02456363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02015962 — Surrogate Endpoint (SUR): Serum potassium
Study NCT01753648 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05178719 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03786367 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00063401 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01172717 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01172717 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03753451 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT02065258 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03828019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00874419 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00874419 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00056797 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00329797 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00329797 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04110197 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT01392807 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT00370201 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT01858935 — Predictive Biomarker (PRD): SERPINH1 mRNA
Genes: SERPINH1; CBP1; CBP2; HSP47; SERPINH2; PIG14
Study NCT00452361 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study NCT04651101 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03512847 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01878565 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05671900 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT03783078 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT00986986 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01200836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04583371 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01867697 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02922296 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04522830 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03803241 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02174822 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT00131846 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03871218 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02282683 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02282683 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03411122 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT03546452 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT01167244 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01383148 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT01383148 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03227419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03227419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03517631 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02948517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02948517 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02948517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04212741 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00418756 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00291759 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00291759 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04150380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01420484 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03840330 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02635620 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02389270 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02389270 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02389270 — Safety Biomarker (SAF): BDNF
Study NCT01046500 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01046500 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT02740075 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02740075 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02981069 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00804388 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01889849 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT01163058 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01163058 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01163058 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT01163058 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01163058 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00067704 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02140593 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT02386384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02386384 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02467634 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02551549 — Predictive Biomarker (PRD): CD101 mRNA
Genes: CD101; EWI101; IGSF2; V7
Study NCT01964235 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01133171 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03308396 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03114852 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study NCT01575535 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT01575535 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study NCT00658164 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study NCT02745561 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02532270 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01375764 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03944239 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT00145210 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03195218 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00778843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01772784 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02802501 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT05295667 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT03058328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03353337 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00942994 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00005297 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00047164 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT04468217 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01542684 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04602871 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00710606 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT02649751 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03966339 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01701232 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01900418 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01698034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01698034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03391739 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00921518 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01750879 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00811226 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00550862 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT04275115 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT04275115 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00901888 — Predictive Biomarker (PRD): APLNR mRNA
Genes: APLNR; AGTRL1; APJ
Study NCT02549482 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02989428 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04641884 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study NCT04641884 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00460343 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01209026 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01617746 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT04135287 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04588454 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03516643 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT04036669 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT04036669 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04346355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03039491 — Surrogate Endpoint (SUR): Opsonophagocytic antibody response
Study NCT04202328 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00950820 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00950820 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02090842 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02847338 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00923611 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01553370 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04744987 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02242448 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02895867 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01475201 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01307631 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04343235 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03220906 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00308620 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03059680 — Surrogate Endpoint (SUR): Serum potassium
Study NCT00392470 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02745015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03858959 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT03858959 — Surrogate Endpoint (SUR): Bacterial count
Study NCT01952587 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT00785057 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01520402 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01520402 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT01520402 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study NCT01339520 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03607279 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04535453 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02569164 — Surrogate Endpoint (SUR): Blood pressure