TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04630600 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02003469 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03926936 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT03926936 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00295646 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02075086 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01603043 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01305252 — Predictive Biomarker (PRD): S100A4 mRNA
Genes: S100A4; CAPL; MTS1
Study NCT01305252 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04014894 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00843440 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03547908 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00002919 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT00498043 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04410965 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study NCT04118543 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04035733 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT00309907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01190007 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01190007 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01190007 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00428519 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT00428519 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00906412 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT01237431 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02530476 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02732899 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02732899 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04803474 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT01165125 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03420144 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT02529995 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02529995 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02607410 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00444600 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00444600 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01265992 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT03740009 — Predictive Biomarker (PRD): TESC mRNA
Genes: TESC; CHP3
Study NCT03227029 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00819325 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT01981837 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT02976116 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02544347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02276742 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03108521 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03469167 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04436445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02628444 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00436072 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00436072 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00436072 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00005903 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study NCT02270710 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study NCT02270710 — Predictive Biomarker (PRD): IRF5 mRNA
Genes: IRF5
Study NCT02270710 — Predictive Biomarker (PRD): DEF6 mRNA
Genes: DEF6; IBP
Study NCT03761420 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00855374 — Predictive Biomarker (PRD): F2RL3 mRNA
Genes: F2RL3; PAR4
Study NCT00376636 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00376636 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00042445 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study NCT02988544 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT01353001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00670566 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01869543 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT04877067 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02108210 — Safety Biomarker (SAF): Interleukin 1
Study NCT03439046 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03439046 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT03439046 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01612169 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03374358 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT03374358 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study NCT02933944 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00237770 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03169296 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study NCT00418496 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02515799 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT02515799 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04709003 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02452073 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04528472 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00412321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00638911 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02479880 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02341651 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05592925 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00893425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00893425 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02575560 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02399943 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02399943 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT02399943 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02399943 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study NCT02399943 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02652910 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02652910 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT02652910 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01527422 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03618667 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03618667 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02671006 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT04572646 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT01541631 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03201861 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03201861 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01065025 — Predictive Biomarker (PRD): KIF11 mRNA
Genes: KIF11; EG5; KNSL1; TRIP5
Study NCT00570323 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00570323 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05357768 — Predictive Biomarker (PRD): BCOR mRNA
Genes: BCOR; KIAA1575
Study NCT05357768 — Predictive Biomarker (PRD): CCN3 mRNA
Genes: CCN3; IGFBP9; NOV; NOVH
Study NCT01905189 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04280991 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT05238350 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study NCT03737591 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02761239 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT03149523 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04399148 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study NCT01104480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00209144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01640015 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01324960 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03183752 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT01354522 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01354522 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01984047 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study NCT01533870 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT00148863 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01580319 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04404881 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04404881 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03962959 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02389465 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03200626 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01456013 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02282267 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00130156 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03103646 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05042024 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study NCT02109289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01705340 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01705340 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02546726 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00325507 — Predictive Biomarker (PRD): TPBG mRNA
Genes: TPBG; 5T4
Study NCT00325507 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01122446 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00069693 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00069693 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01111227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02522169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00360178 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03483792 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01157832 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01918241 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02148068 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00011154 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00741637 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02129725 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02309658 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study NCT04256278 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT04256278 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04393662 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study NCT03260140 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01042639 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT03833661 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT00439569 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT00436436 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03206684 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00035828 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00001280 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01302236 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03538886 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study NCT00621569 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00145314 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00785512 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01997944 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01723631 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study NCT01748110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00005269 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01752556 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00550342 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01824485 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02628678 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT01198028 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01198028 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03861364 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02725762 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01945125 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT03968354 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT06235424 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT04351529 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01771731 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01747486 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01877343 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02993744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02820116 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02820116 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01042158 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01042158 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00172224 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01427218 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02336815 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04128319 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT03658928 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02879513 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00125970 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05067881 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02480088 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT01466465 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00153569 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00951379 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study NCT05940506 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT01281163 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02877069 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00664404 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT00820144 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study NCT04101968 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT04101968 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01144468 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02466516 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study NCT00390793 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00390793 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04780035 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04261465 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04261465 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT00003868 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT03134625 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02731755 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01635192 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01635192 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study NCT01288469 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01670968 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study NCT01670968 — Predictive Biomarker (PRD): SREBF2 mRNA
Genes: SREBF2; BHLHD2; SREBP2
Study NCT01689844 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03231722 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05346978 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study NCT05346978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study NCT05346978 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study NCT05346978 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study NCT05346978 — Predictive Biomarker (PRD): FOXO6 mRNA
Genes: FOXO6
Study NCT03381820 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03966846 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00194974 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02654496 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT00912574 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03011749 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00617331 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01673516 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02759913 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02275377 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01312727 — Safety Biomarker (SAF): Uromodulin
Genes: UMOD
Study NCT01312727 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01312727 — Predictive Biomarker (PRD): NPHP1 mRNA
Genes: NPHP1; NPH1
Study NCT03000842 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00338650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00265200 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study NCT01701960 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04169178 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04169178 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT00947453 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT01865253 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00329251 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05188781 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00591500 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02995655 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT02995655 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT02995655 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT02995655 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT02995655 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study NCT02995655 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study NCT02995655 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study NCT02093715 — Predictive Biomarker (PRD): Exhaled nitric oxide