TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04975048 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00704106 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00893711 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT00893711 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT04321863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00395538 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02286089 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT02026388 — Predictive Biomarker (PRD): APRT mRNA
Genes: APRT
Study NCT04074993 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00815971 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00815971 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03431935 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00877097 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02791152 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03784924 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT01568411 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02038478 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00341601 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study NCT00341601 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT02086279 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01723787 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00224406 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT02389374 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT04144218 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01137136 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study NCT03681184 — Predictive Biomarker (PRD): PHC1 mRNA
Genes: PHC1; EDR1; PH1
Study NCT01418560 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00463073 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00463073 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00706849 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01382511 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study NCT04103918 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00770861 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01412242 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01867073 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT00682968 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02464319 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02263664 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00816218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02095431 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01773395 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01931176 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05760625 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05760625 — Safety Biomarker (SAF): BDNF
Study NCT03042702 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01124630 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT01992159 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01146210 — Predictive Biomarker (PRD): FANCD2 mRNA
Genes: FANCD2; FACD
Study NCT03700710 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00376428 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00613847 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02977884 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04368052 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT02155803 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02300376 — Safety Biomarker (SAF): 51Cr-EDTA
Study NCT04292574 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT04330300 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04100655 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02528617 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01650467 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04255134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02693184 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03063632 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02474355 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02474355 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04618887 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study NCT02271490 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03435900 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02119130 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04582227 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01783405 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT01914133 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02042105 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03722290 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study NCT03722290 — Predictive Biomarker (PRD): EIF4E mRNA
Genes: EIF4E; EIF4EL1; EIF4F
Study NCT03722290 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT03722290 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study NCT02034136 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00857610 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00950417 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00950417 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00733889 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00303992 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03630276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00686374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01363791 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01612910 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00579007 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03115255 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03115255 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01042977 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01073189 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00563940 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00563940 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00857246 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03690791 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01527825 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01774071 — Predictive Biomarker (PRD): STEAP1 mRNA
Genes: STEAP1; PRSS24; STEAP
Study NCT04579497 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01434225 — Predictive Biomarker (PRD): IKBKG mRNA
Genes: IKBKG; FIP3; NEMO
Study NCT00533559 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00332657 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00124397 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04174950 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT00313287 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03864354 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00752856 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT00752856 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00669760 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study NCT00669760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00288171 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT04526990 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03559764 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT01226056 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01226056 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01226056 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01226056 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00401401 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04611282 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT03095703 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT00001965 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01169597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05421403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00003248 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00002669 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04635670 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT02424669 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00632632 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00632632 — Safety Biomarker (SAF): BDNF
Study NCT02061995 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01435993 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02316444 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02798523 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT00723658 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01232309 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03070210 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study NCT04918901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03689231 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT01042301 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study NCT01042301 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02417415 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04388371 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT02283177 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01438554 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02044328 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01386671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01386671 — Safety Biomarker (SAF): Interleukin 1
Study NCT04754373 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04754373 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02198677 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03420222 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT02704429 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00091793 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03294083 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02454231 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT02454231 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02140684 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT04452799 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT00293280 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03174574 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT01742923 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03071432 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01652196 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02375022 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02375022 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01113047 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01912118 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03579654 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03579654 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00640783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03502135 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02837172 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT02947061 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01382069 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study NCT00060892 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT01301885 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT00297050 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03239561 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00001761 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01604564 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT01914965 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00275015 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00275015 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01524289 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03911609 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00870493 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03208959 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT03208959 — Predictive Biomarker (PRD): TDO2 mRNA
Genes: TDO2; TDO
Study NCT04157556 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT04157556 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT02062931 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02534337 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT03556696 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03845179 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03845179 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01377467 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04050332 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00006425 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00006425 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT00006425 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT03163238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04779021 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00500409 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01619618 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01619618 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study NCT01864135 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT00247325 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02614794 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03701789 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00003568 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02601937 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study NCT03723590 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03952156 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02143934 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT01553409 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01129154 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03721848 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01293669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01068587 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01068587 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01041339 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT03858465 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02882373 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01089777 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study NCT03098771 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01387945 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01950156 — Predictive Biomarker (PRD): KIF20A mRNA
Genes: KIF20A; MKLP2; RAB6KIFL
Study NCT01950156 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00691574 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study NCT04141618 — Predictive Biomarker (PRD): NLRP7 mRNA
Genes: NLRP7; NALP7; NOD12; PYPAF3
Study NCT06512493 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT04677842 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00477074 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT00300209 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00607750 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02984683 — Predictive Biomarker (PRD): CA6 mRNA
Genes: CA6
Study NCT02121353 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01208181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01165008 — Safety Biomarker (SAF): Interleukin 1
Study NCT00495846 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT00988767 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01309126 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03008551 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00638261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00920309 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT00398489 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01998685 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01998685 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01276197 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01275339 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01275339 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study NCT01221454 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02044497 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02044497 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04079777 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04079777 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT03779399 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT03608956 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03515798 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01147965 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00670878 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00670878 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01526434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02390843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2