TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02542670 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT00784706 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT02644772 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00322387 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01855841 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT04645576 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03944304 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT02685618 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01152411 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01802268 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study NCT03624790 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04601844 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT03641794 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT03641794 — Predictive Biomarker (PRD): TDO2 mRNA
Genes: TDO2; TDO
Study NCT03372447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02887365 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT02217683 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02944734 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04119388 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04623255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04776889 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04776889 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study NCT04776889 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03889990 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01924195 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01924195 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study NCT03906201 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01556789 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT01307410 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00850928 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT00357786 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT03285204 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00831857 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04134377 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03726541 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01193049 — Safety Biomarker (SAF): Th2 cell
Study NCT01193049 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT01193049 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT03535090 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT04146402 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT02092324 — Predictive Biomarker (PRD): CSF3R mRNA
Genes: CSF3R; GCSFR
Study NCT01945788 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01372813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01372813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01372813 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01372813 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02451254 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02451254 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00616772 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03632551 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT00398138 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01131429 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04506281 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02061904 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02005510 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01413828 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00669513 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00068484 — Pharmacodynamic Biomarker (PDY): DNA topoisomerase I
Genes: TOP1
Study NCT02428075 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03136003 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03315858 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03315858 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03315858 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01581996 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00671970 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00671970 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT00671970 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00671970 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study NCT00671970 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00671970 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04489940 — Predictive Biomarker (PRD): HMGA2 mRNA
Genes: HMGA2; HMGIC
Study NCT05514925 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01226472 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study NCT03860623 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT03199131 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04567953 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01547806 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01547806 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01379560 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03193944 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04131205 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04173403 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04173403 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00767299 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01810822 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study NCT01810822 — Predictive Biomarker (PRD): GPX4 mRNA
Genes: GPX4
Study NCT00748332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01392235 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01392235 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01392235 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study NCT02161523 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02161523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02161523 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02161523 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00133185 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02120469 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03030391 — Predictive Biomarker (PRD): PDE4B mRNA
Genes: PDE4B; DPDE4
Study NCT02741310 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00171002 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02438761 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00012207 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01394211 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00856817 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT03011775 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT03011775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01723085 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT03650049 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03850171 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT01615692 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT02559180 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02559180 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02038725 — Predictive Biomarker (PRD): ABCD2 mRNA
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study NCT02038725 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03634293 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT00653068 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01305941 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01305941 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00030160 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01428986 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01322529 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00020449 — Safety Biomarker (SAF): Interleukin 12
Study NCT02779530 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study NCT01061840 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02774668 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT04461704 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03050892 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT02089867 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01140165 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02816060 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT02233322 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00981929 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00981929 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00981929 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00981929 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT00981929 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02654457 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT02067455 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02766010 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02766010 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03630523 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03375697 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04813289 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02283333 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT02792036 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study NCT03399786 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00096551 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03389451 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01637857 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT02037204 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01844570 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03597542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03597542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03597542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03011554 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03373500 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01372202 — Predictive Biomarker (PRD): CHFR mRNA
Genes: CHFR; RNF196
Study NCT00019136 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04456049 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01855997 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03694067 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT00943410 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04364022 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04251741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00040521 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study NCT03866434 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT03066310 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04171167 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00054756 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study NCT00449488 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study NCT04601181 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03761134 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00718250 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT02756546 — Safety Biomarker (SAF): miR-181a
Study NCT02756546 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT00527514 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03582436 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT04585568 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01599819 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study NCT00746473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00746473 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05305001 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT05305001 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT05305001 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT05305001 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study NCT05305001 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study NCT05305001 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT05305001 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT03530761 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT01799161 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study NCT04024449 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01136460 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study NCT01136460 — Predictive Biomarker (PRD): MYOC mRNA
Genes: MYOC; GLC1A; TIGR
Study NCT02733146 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT04106180 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03633513 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT03633513 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT03633513 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03633513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02149173 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT02149173 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03744598 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00252317 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03418220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01237223 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01070706 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04329559 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01366534 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT01366534 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02027272 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06486870 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03645915 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study NCT03645915 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT01140776 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT00045357 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01023373 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01023373 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00654823 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00654823 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT00725829 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT01764022 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02740894 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06446895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06446895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06446895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03634228 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT00659906 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00553618 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05793463 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00797810 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00952770 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06279780 — Predictive Biomarker (PRD): MFN1 mRNA
Genes: MFN1
Study NCT06279780 — Predictive Biomarker (PRD): FIS1 mRNA
Genes: FIS1; TTC11; CGI-135
Study NCT06279780 — Predictive Biomarker (PRD): DNM1L mRNA
Genes: DNM1L; DLP1; DRP1
Study NCT06279780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06279780 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT06279780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06279780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06279780 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06279780 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study NCT06279780 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT06279780 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT06279780 — Safety Biomarker (SAF): Interleukin 1
Study NCT05016440 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00817037 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00351390 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02391545 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00839436 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00839436 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02365805 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02876003 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00664456 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04459078 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04459078 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01542749 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00346177 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00695370 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01524926 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01524926 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00215189 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01585415 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02410590 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT00985621 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT00316589 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00415753 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03256136 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1