TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18192839 — Surrogate Endpoint (SUR): Blood pressure
Study 10945313 — Surrogate Endpoint (SUR): Blood pressure
Study 9323507 — Predictive Biomarker (PRD): HMX1 mRNA
Genes: HMX1; H6
Study 8405008 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8405008 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30219475 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 25747955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20063120 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 8932271 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 31699946 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 26354927 — Predictive Biomarker (PRD): ATRX mRNA
Genes: ATRX; RAD54L; XH2
Study 26354927 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 26354927 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 26354927 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 26354927 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 26354927 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26354927 — Predictive Biomarker (PRD): H3-3A mRNA
Genes: H3-3A; H3.3A; H3F3; H3F3A; PP781;; H3-3B; H3.3B; H3F3B
Study 26354927 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 26354927 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 23761303 — Surrogate Endpoint (SUR): Bone mineral density
Study 28604133 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 26892849 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 23842081 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 11299845 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 30125052 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30125052 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20735822 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 20735822 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 17196275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17196275 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17196275 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17196275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17196275 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6726466 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 31174397 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23866945 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 23866945 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21346160 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 21346160 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 19332958 — Surrogate Endpoint (SUR): Blood pressure
Study 16537682 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8622332 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22321357 — Surrogate Endpoint (SUR): Serum testosterone
Study 15780963 — Surrogate Endpoint (SUR): Bone mineral density
Study 9744643 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 21452294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21452294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10875098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2852692 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 2852692 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 2852692 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 27875943 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24750544 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 26373822 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 26373822 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 26373822 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 17689968 — Predictive Biomarker (PRD): NR4A3 mRNA
Genes: NR4A3; CHN; CSMF; MINOR; NOR1; TEC
Study 10643541 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 27872058 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 19210857 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 31678988 — Surrogate Endpoint (SUR): Blood pressure
Study 30114561 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 25197922 — Safety Biomarker (SAF): Hyaluronic acid
Study 11860971 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15751665 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15751665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15751665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30759445 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 26715213 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 26715213 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 26715213 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26715213 — Predictive Biomarker (PRD): NR1I2 mRNA
Genes: NR1I2; PXR
Study 26715213 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 23173250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23173250 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20595543 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18046056 — Surrogate Endpoint (SUR): Blood pressure
Study 28688704 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22045831 — Safety Biomarker (SAF): Reactive oxygen species
Study 22045831 — Surrogate Endpoint (SUR): Serum creatinine
Study 22045831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11428852 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30717691 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 8959469 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11576201 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 7664505 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28244635 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28244635 — Surrogate Endpoint (SUR): Blood pressure
Study 28244635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11756982 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11756982 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12614254 — Surrogate Endpoint (SUR): Serum testosterone
Study 10568572 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 10568572 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28757109 — Surrogate Endpoint (SUR): Blood pressure
Study 19549737 — Surrogate Endpoint (SUR): Blood pressure
Study 10767783 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 10767783 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 12764404 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 12764404 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12764404 — Surrogate Endpoint (SUR): Blood pressure
Study 8942596 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 8942596 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8942596 — Surrogate Endpoint (SUR): Blood pressure
Study 1758253 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17907276 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 8638865 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8638865 — Surrogate Endpoint (SUR): Blood pressure
Study 1569238 — Surrogate Endpoint (SUR): Blood pressure
Study 2997314 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12164986 — Surrogate Endpoint (SUR): Blood pressure
Study 7598140 — Surrogate Endpoint (SUR): Bone mineral density
Study 22972694 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 22972694 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22972694 — Predictive Biomarker (PRD): Hormone receptor
Study 19218270 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 10553855 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 21544087 — Surrogate Endpoint (SUR): Blood pressure
Study 12105408 — Surrogate Endpoint (SUR): Blood pressure
Study 2695287 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2695287 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23348881 — Surrogate Endpoint (SUR): Blood pressure
Study 8201953 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 8201953 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 129002 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30230409 — Predictive Biomarker (PRD): AGL mRNA
Genes: AGL; GDE
Study 16048810 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16048810 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 29572094 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 22251436 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 9790083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9790083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9790083 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6764750 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 28481007 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7933440 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25913417 — Surrogate Endpoint (SUR): Blood pressure
Study 20647285 — Surrogate Endpoint (SUR): Blood pressure
Study 29573355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15531906 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15531906 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10990148 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 30651573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30651573 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study 30651573 — Predictive Biomarker (PRD): IL6ST mRNA
Genes: IL6ST
Study 24090427 — Surrogate Endpoint (SUR): Bone mineral density
Study 29141087 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2976414 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 24986722 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study 18573823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8983446 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29696360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27583311 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 25924781 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25924781 — Surrogate Endpoint (SUR): Blood pressure
Study 22177779 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 21400196 — Surrogate Endpoint (SUR): Bone mineral density
Study 16469753 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15531001 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15531001 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1483439 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29982704 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9469496 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19772447 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19772447 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17294445 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17294445 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 11158191 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11158191 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9358196 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3673877 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29661497 — Predictive Biomarker (PRD): NDP mRNA
Genes: NDP; EVR2
Study 24846652 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 24846652 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15662232 — Surrogate Endpoint (SUR): Blood pressure
Study 10549114 — Safety Biomarker (SAF): Hyaluronic acid
Study 21652583 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 26937774 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20932189 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 16324343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16324343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16324343 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12196338 — Surrogate Endpoint (SUR): Blood pressure
Study 26040633 — Surrogate Endpoint (SUR): Blood pressure
Study 22485058 — Surrogate Endpoint (SUR): Blood pressure
Study 19761936 — Surrogate Endpoint (SUR): Blood pressure
Study 11448321 — Surrogate Endpoint (SUR): Blood pressure
Study 3173455 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31816875 — Predictive Biomarker (PRD): RELA mRNA
Genes: RELA; NFKB3
Study 31816875 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 28522220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28522220 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15089806 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 15089806 — Surrogate Endpoint (SUR): Blood pressure
Study 7868672 — Safety Biomarker (SAF): Reactive oxygen species
Study 7868672 — Surrogate Endpoint (SUR): Sperm parameters
Study 3280220 — Surrogate Endpoint (SUR): Blood pressure
Study 30649752 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 23485520 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 21515206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12324912 — Surrogate Endpoint (SUR): Blood pressure
Study 27569351 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 24844611 — Surrogate Endpoint (SUR): Bone mineral density
Study 14559319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19717534 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17337164 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 21517955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21517955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21517955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10690445 — Surrogate Endpoint (SUR): Bone mineral density
Study 3767127 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3662385 — Surrogate Endpoint (SUR): Blood pressure
Study 12443672 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 10442154 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 8546287 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8546287 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8546287 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8546287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8546287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 820703 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30922964 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15365065 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 15365065 — Surrogate Endpoint (SUR): Bone mineral density
Study 11713926 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 18332475 — Predictive Biomarker (PRD): Hormone receptor
Study 12664054 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28196620 — Surrogate Endpoint (SUR): Blood pressure
Study 22473163 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 2177746 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15288885 — Surrogate Endpoint (SUR): Blood pressure
Study 22006050 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22006050 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21785963 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 19350340 — Surrogate Endpoint (SUR): Bone mineral density
Study 17254760 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15284603 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 31303390 — Surrogate Endpoint (SUR): Blood pressure
Study 31303390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28381516 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 20008182 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 31594375 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19320235 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9546962 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 30575683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25716971 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 25716971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10989321 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9194510 — Surrogate Endpoint (SUR): Blood pressure
Study 3929694 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 16645424 — Surrogate Endpoint (SUR): Serum potassium
Study 12870137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 21545397 — Surrogate Endpoint (SUR): Blood pressure
Study 11353877 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11353877 — Safety Biomarker (SAF): Protein AMBP
Genes: AMBP; HCP; ITIL
Study 11353877 — Surrogate Endpoint (SUR): Blood pressure
Study 18676275 — Predictive Biomarker (PRD): PRAC1 mRNA
Genes: PRAC1; C17orf92; PRAC
Study 10685667 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8775698 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 6150000 — Surrogate Endpoint (SUR): Blood pressure
Study 30230920 — Surrogate Endpoint (SUR): Blood pressure
Study 26851191 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 24532078 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7564363 — Surrogate Endpoint (SUR): Blood pressure
Study 2197005 — Surrogate Endpoint (SUR): Blood pressure
Study 20922438 — Surrogate Endpoint (SUR): Bone mineral density
Study 16705107 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16705107 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10071280 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 10071280 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study 29361199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29361199 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29361199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29361199 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18316794 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18316794 — Predictive Biomarker (PRD): Hormone receptor
Study 16717170 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 2446057 — Surrogate Endpoint (SUR): Blood pressure
Study 30400774 — Surrogate Endpoint (SUR): Blood pressure
Study 20569086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20569086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18520294 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18520294 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor