TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27616217 — Surrogate Endpoint (SUR): Blood pressure
Study 27616217 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12875474 — Surrogate Endpoint (SUR): Blood pressure
Study 10375185 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25371053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17998780 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 68285 — Surrogate Endpoint (SUR): Blood pressure
Study 31782931 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 31782931 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31782931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31782931 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25560820 — Surrogate Endpoint (SUR): Bone mineral density
Study 29470249 — Surrogate Endpoint (SUR): Serum uric acid
Study 18387159 — Surrogate Endpoint (SUR): Serum calcium
Study 20043182 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2021446 — Surrogate Endpoint (SUR): Blood pressure
Study 25016922 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 19843060 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19843060 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 17495570 — Surrogate Endpoint (SUR): Bone mineral density
Study 11940299 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 30848558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26803169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17660482 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 1599635 — Surrogate Endpoint (SUR): Blood pressure
Study 10848660 — Surrogate Endpoint (SUR): Serum creatinine
Study 22504093 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 19796735 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25190442 — Surrogate Endpoint (SUR): Blood pressure
Study 18245544 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 18245544 — Safety Biomarker (SAF): MTHFR
Study 12574925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27543065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22546175 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22546175 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24911076 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17178634 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17178634 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 17178634 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17178634 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17178634 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 12161090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7887382 — Surrogate Endpoint (SUR): Blood pressure
Study 7887382 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22221427 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19224761 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 17301297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23564755 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16140028 — Safety Biomarker (SAF): Hyaluronic acid
Study 9363868 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 1306735 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 20835747 — Surrogate Endpoint (SUR): Blood pressure
Study 10501150 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 28033254 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 28033254 — Predictive Biomarker (PRD): BCL2A1 mRNA
Genes: BCL2A1; BCL2L5; BFL1; GRS; HBPA1
Study 28033254 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 20185655 — Surrogate Endpoint (SUR): Blood pressure
Study 18035201 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 10070128 — Surrogate Endpoint (SUR): Blood pressure
Study 6112386 — Surrogate Endpoint (SUR): Blood pressure
Study 28006059 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26338693 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19434784 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 28135225 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23565660 — Predictive Biomarker (PRD): Liver iron
Study 23565660 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7867225 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15860686 — Surrogate Endpoint (SUR): Blood pressure
Study 9347069 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 7685176 — Surrogate Endpoint (SUR): Blood pressure
Study 19029083 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19029083 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 19029083 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8777296 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8777296 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 1806610 — Surrogate Endpoint (SUR): Serum calcium
Study 31348579 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31348579 — Predictive Biomarker (PRD): Microsatellite instability
Study 21863237 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21863237 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14978184 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 11230885 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 9737645 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2537563 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18439662 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17062966 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17062966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22532639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22532639 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18585837 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 18585837 — Surrogate Endpoint (SUR): Blood pressure
Study 18585837 — Surrogate Endpoint (SUR): Serum creatinine
Study 8862477 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 22564753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22564753 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 22564753 — Safety Biomarker (SAF): Reactive oxygen species
Study 22564753 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 22564753 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17671159 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 16536310 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9445297 — Surrogate Endpoint (SUR): Bone mineral density
Study 24028942 — Surrogate Endpoint (SUR): Blood pressure
Study 24028942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22319896 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9783499 — Surrogate Endpoint (SUR): Blood pressure
Study 7841749 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 7841749 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3074295 — Surrogate Endpoint (SUR): Blood pressure
Study 31704275 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 24633624 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28817370 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16753687 — Surrogate Endpoint (SUR): Blood pressure
Study 16753687 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16753687 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15484298 — Safety Biomarker (SAF): Hyaluronic acid
Study 27389172 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16941030 — Surrogate Endpoint (SUR): Blood pressure
Study 16941030 — Surrogate Endpoint (SUR): Serum creatinine
Study 10935770 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 19965781 — Safety Biomarker (SAF): Reactive oxygen species
Study 12401635 — Surrogate Endpoint (SUR): Blood pressure
Study 10087420 — Surrogate Endpoint (SUR): Blood pressure
Study 22781558 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20471117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17260161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17260161 — Surrogate Endpoint (SUR): Plasma ammonia
Study 14696754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25670360 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16478755 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 11157334 — Surrogate Endpoint (SUR): Bone mineral density
Study 26654125 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 9258756 — Surrogate Endpoint (SUR): Bone mineral density
Study 25658671 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 23829776 — Surrogate Endpoint (SUR): Bone mineral density
Study 10543320 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10543320 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30249203 — Surrogate Endpoint (SUR): Blood pressure
Study 27481309 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 15963095 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 1834765 — Predictive Biomarker (PRD): PHLPP1 mRNA
Genes: PHLPP1; KIAA0606; PHLPP; PLEKHE1; SCOP
Study 20692141 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20692141 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17584562 — Surrogate Endpoint (SUR): Serum creatinine
Study 9648966 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 21565956 — Surrogate Endpoint (SUR): Serum creatinine
Study 12830441 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12830441 — Surrogate Endpoint (SUR): Serum calcium
Study 20525705 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9579244 — Surrogate Endpoint (SUR): Blood pressure
Study 7714108 — Safety Biomarker (SAF): Interleukin 1
Study 21282282 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17200216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27686971 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22682335 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 11990445 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 1644080 — Surrogate Endpoint (SUR): Blood pressure
Study 26027619 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 26027619 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21744143 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 21744143 — Surrogate Endpoint (SUR): Blood pressure
Study 2192529 — Surrogate Endpoint (SUR): Blood pressure
Study 353597 — Surrogate Endpoint (SUR): Blood pressure
Study 27901186 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27901186 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29862411 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29862411 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20833991 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20833991 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20833991 — Surrogate Endpoint (SUR): Blood pressure
Study 19636365 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 11410114 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16708310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15844469 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15844469 — Surrogate Endpoint (SUR): Bone mineral density
Study 12572380 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12572380 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25012399 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 12785003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12785003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12785003 — Safety Biomarker (SAF): IL-6 and IL-10
Study 27624485 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11033836 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 7712685 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7712685 — Surrogate Endpoint (SUR): Blood pressure
Study 29983230 — Surrogate Endpoint (SUR): Serum creatinine
Study 24974806 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9491905 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28003540 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 25011019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25011019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25011019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25011019 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17725940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30790396 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27456461 — Surrogate Endpoint (SUR): Blood pressure
Study 11679464 — Surrogate Endpoint (SUR): Blood pressure
Study 23832078 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 16434603 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 26749726 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 1504913 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1504913 — Surrogate Endpoint (SUR): Serum potassium
Study 30953165 — Predictive Biomarker (PRD): DPEP1 mRNA
Genes: DPEP1; MDP; RDP
Study 26440233 — Surrogate Endpoint (SUR): Blood pressure
Study 31005596 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29092739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23456922 — Surrogate Endpoint (SUR): Bone mineral density
Study 22066459 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17019520 — Surrogate Endpoint (SUR): Serum calcium
Study 10949718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10463623 — Surrogate Endpoint (SUR): Blood pressure
Study 7756796 — Surrogate Endpoint (SUR): Blood pressure
Study 18281145 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 18281145 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 31319484 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23984806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23984806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23984806 — Surrogate Endpoint (SUR): Blood pressure
Study 15289633 — Surrogate Endpoint (SUR): Blood pressure
Study 9303287 — Surrogate Endpoint (SUR): Blood pressure
Study 21047922 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25530054 — Surrogate Endpoint (SUR): Blood pressure
Study 16186288 — Surrogate Endpoint (SUR): Blood pressure
Study 22873342 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29369159 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29369159 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29369159 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 29369159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26663359 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18154644 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 6283873 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31382977 — Predictive Biomarker (PRD): GZMH mRNA
Genes: GZMH; CGL2; CTSGL2
Study 31382977 — Predictive Biomarker (PRD): ADGRG1 mRNA
Genes: ADGRG1; GPR56; TM7LN4; TM7XN1; UNQ540/PRO1083
Study 31382977 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 31382977 — Predictive Biomarker (PRD): KLRD1 mRNA
Genes: KLRD1; CD94
Study 31382977 — Predictive Biomarker (PRD): S1PR5 mRNA
Genes: S1PR5; EDG8
Study 31382977 — Predictive Biomarker (PRD): PRF1 mRNA
Genes: PRF1; PFP
Study 9535154 — Surrogate Endpoint (SUR): Blood pressure
Study 2761587 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 323326 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 323326 — Surrogate Endpoint (SUR): Forced vital capacity
Study 323326 — Surrogate Endpoint (SUR): Blood pressure
Study 28445631 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 23820464 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 15338971 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15338971 — Surrogate Endpoint (SUR): Blood pressure
Study 8216441 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23942318 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 24843430 — Surrogate Endpoint (SUR): Blood pressure
Study 24843430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27511183 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 22972030 — Predictive Biomarker (PRD): ANGPTL4 mRNA
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 17211088 — Surrogate Endpoint (SUR): Bone mineral density
Study 10681767 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10681767 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26087654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26087654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9591932 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28241231 — Surrogate Endpoint (SUR): Serum testosterone
Study 28241231 — Surrogate Endpoint (SUR): Bone mineral density
Study 21267037 — Surrogate Endpoint (SUR): Blood pressure
Study 15315622 — Predictive Biomarker (PRD): ARX mRNA
Genes: ARX
Study 15315622 — Surrogate Endpoint (SUR): Blood pressure
Study 11333992 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24156287 — Surrogate Endpoint (SUR): Blood pressure
Study 2568348 — Surrogate Endpoint (SUR): Blood pressure
Study 31127666 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9068154 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 25474278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 25474278 — Predictive Biomarker (PRD): Microsatellite instability
Study 1806619 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 6412376 — Surrogate Endpoint (SUR): Serum calcium
Study 22723325 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15797959 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 15797959 — Surrogate Endpoint (SUR): Bone mineral density
Study 9616311 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 31984567 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31434637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27459198 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 27459198 — Surrogate Endpoint (SUR): Blood pressure
Study 24515621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24515621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24515621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2