TrialPanorama/TrialPanorama-database huggingface dataset:
Study 14567559 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 2566321 — Surrogate Endpoint (SUR): Blood pressure
Study 27667329 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27667329 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25453742 — Surrogate Endpoint (SUR): Blood pressure
Study 18772855 — Surrogate Endpoint (SUR): Blood pressure
Study 1656818 — Surrogate Endpoint (SUR): Blood pressure
Study 19808950 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 18423560 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18423560 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12023696 — Surrogate Endpoint (SUR): Blood pressure
Study 10366118 — Surrogate Endpoint (SUR): Bone mineral density
Study 7863988 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7988247 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 29400626 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23751235 — Surrogate Endpoint (SUR): Blood pressure
Study 12667396 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1839435 — Surrogate Endpoint (SUR): Blood pressure
Study 20117262 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 12364420 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 12364420 — Surrogate Endpoint (SUR): Bone mineral density
Study 30518685 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 25689563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23317958 — Surrogate Endpoint (SUR): Sputum culture conversion to negative
Study 31529220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20027579 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23438203 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 15385946 — Surrogate Endpoint (SUR): Blood pressure
Study 26250825 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 26853339 — Predictive Biomarker (PRD): ATRX mRNA
Genes: ATRX; RAD54L; XH2
Study 23022970 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 14977928 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 14977928 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 11450149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7798858 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 3195756 — Surrogate Endpoint (SUR): Blood pressure
Study 30972657 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 25521304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9065902 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 25594919 — Surrogate Endpoint (SUR): Blood pressure
Study 9298044 — Surrogate Endpoint (SUR): Blood pressure
Study 25157002 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16482080 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31536624 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24627569 — Predictive Biomarker (PRD): BCAT1 mRNA
Genes: BCAT1; BCT1; ECA39
Study 24627569 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20823377 — Surrogate Endpoint (SUR): Blood pressure
Study 18565218 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 11522234 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8145983 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22525372 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22525372 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15832486 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15832486 — Surrogate Endpoint (SUR): Blood pressure
Study 10435732 — Safety Biomarker (SAF): 51Cr-EDTA
Study 17353582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15492322 — Surrogate Endpoint (SUR): Blood pressure
Study 9517372 — Surrogate Endpoint (SUR): Blood pressure
Study 31167512 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 19819787 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 24024587 — Surrogate Endpoint (SUR): Blood pressure
Study 22462236 — Surrogate Endpoint (SUR): Blood pressure
Study 10718163 — Surrogate Endpoint (SUR): Blood pressure
Study 26350812 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26350812 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16737665 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16737665 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16737665 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 9770877 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 7819650 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26385025 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23696599 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 15131545 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8187304 — Surrogate Endpoint (SUR): Blood pressure
Study 8187304 — Surrogate Endpoint (SUR): Serum creatinine
Study 11355044 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10332195 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31244668 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 31244668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31244668 — Surrogate Endpoint (SUR): Blood pressure
Study 25222757 — Safety Biomarker (SAF): Cytochrome c
Study 15857930 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 15857930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 8017870 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 2849011 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10933353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10933353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1317048 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 21259026 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21259026 — Surrogate Endpoint (SUR): Blood pressure
Study 17673936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14767287 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11332151 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8424300 — Surrogate Endpoint (SUR): Blood pressure
Study 22559239 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 9738562 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 22698919 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16314784 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 1977079 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21728272 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19367283 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 14741071 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 9107259 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27141626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27141626 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9306024 — Surrogate Endpoint (SUR): Bone mineral density
Study 27238895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27238895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27238895 — Safety Biomarker (SAF): Th2 cell
Study 25897826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10782562 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10782562 — Surrogate Endpoint (SUR): Blood pressure
Study 6791054 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 31429207 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 30615104 — Surrogate Endpoint (SUR): Blood pressure
Study 25881382 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 11720430 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9164318 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31771594 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30615583 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24048718 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 23908479 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12779268 — Predictive Biomarker (PRD): Liver iron
Study 10950766 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8979093 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 1468245 — Safety Biomarker (SAF): Hyaluronic acid
Study 23932494 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23932494 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ESR2 mRNA
Genes: ESR2; ESTRB; NR3A2
Study 15633195 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 10441812 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2172161 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23818692 — Predictive Biomarker (PRD): CPT1A mRNA
Genes: CPT1A; CPT1
Study 18822917 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22498720 — Surrogate Endpoint (SUR): Blood pressure
Study 20089522 — Surrogate Endpoint (SUR): Bone mineral density
Study 10423312 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7437237 — Surrogate Endpoint (SUR): Blood pressure
Study 2221645 — Surrogate Endpoint (SUR): Serum calcium
Study 2221645 — Surrogate Endpoint (SUR): Bone mineral density
Study 24338120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24338120 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 24338120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18274646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7594660 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23553863 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19086108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16647414 — Surrogate Endpoint (SUR): Bone mineral density
Study 29630132 — Surrogate Endpoint (SUR): Blood pressure
Study 9275430 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 29995356 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 29995356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12372764 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11840225 — Surrogate Endpoint (SUR): Blood pressure
Study 11840225 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11840225 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9316695 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 20413999 — Surrogate Endpoint (SUR): Blood pressure
Study 20413999 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20413999 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20413999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12765436 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18323556 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18323556 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 8803503 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8803503 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21663656 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 16622734 — Surrogate Endpoint (SUR): Serum calcium
Study 8737196 — Surrogate Endpoint (SUR): Blood pressure
Study 1555559 — Surrogate Endpoint (SUR): Blood pressure
Study 30135541 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 30135541 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 18599797 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18599797 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26628416 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 31721467 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 30712364 — Surrogate Endpoint (SUR): Blood pressure
Study 11447776 — Safety Biomarker (SAF): Hyaluronic acid
Study 2538252 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 2538252 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8361875 — Surrogate Endpoint (SUR): Blood pressure
Study 31615726 — Safety Biomarker (SAF): Hyaluronic acid
Study 30285758 — Predictive Biomarker (PRD): IZUMO1R mRNA
Genes: IZUMO1R; FOLR4; JUNO
Study 27180023 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27180023 — Surrogate Endpoint (SUR): Blood pressure
Study 24758546 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 1552406 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 3927481 — Surrogate Endpoint (SUR): Serum triglycerides
Study 3927481 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27513854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27513854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27513854 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24464960 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22706026 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 22706026 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20331585 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 20331585 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 20331585 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 20331585 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 10757194 — Surrogate Endpoint (SUR): Blood pressure
Study 29283791 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 21819548 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27824398 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23835718 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 22085343 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8440099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27551937 — Surrogate Endpoint (SUR): Blood pressure
Study 25281277 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25281277 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 25281277 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23587451 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29034576 — Surrogate Endpoint (SUR): Blood pressure
Study 8205270 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8205270 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31560382 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25350130 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22035157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12366624 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10404843 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7318331 — Surrogate Endpoint (SUR): Blood pressure
Study 29251360 — Surrogate Endpoint (SUR): Serum creatinine
Study 2645063 — Surrogate Endpoint (SUR): Blood pressure
Study 24887794 — Predictive Biomarker (PRD): ABRA mRNA
Genes: ABRA
Study 16005497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15699240 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15699240 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 9057338 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 1853145 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28562792 — Surrogate Endpoint (SUR): Blood pressure
Study 23676888 — Surrogate Endpoint (SUR): Serum uric acid
Study 23676888 — Surrogate Endpoint (SUR): Serum creatinine
Study 23676888 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23676888 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23676888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23676888 — Surrogate Endpoint (SUR): Blood pressure
Study 11706485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27079740 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25840742 — Safety Biomarker (SAF): DRD2
Study 23485622 — Surrogate Endpoint (SUR): Blood pressure
Study 9625308 — Safety Biomarker (SAF): GSTM1
Genes: MU; H-B
Study 528285 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 30156030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30156030 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21718536 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 9022529 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9022529 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30130712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21913862 — Safety Biomarker (SAF): Interleukin 1
Study 21913862 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18984493 — Surrogate Endpoint (SUR): Blood pressure
Study 28283026 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 16371294 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 1464896 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20558628 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17355300 — Surrogate Endpoint (SUR): Blood pressure
Study 16285944 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 31935779 — Surrogate Endpoint (SUR): Blood pressure
Study 21874538 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21874538 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19673654 — Surrogate Endpoint (SUR): Serum creatinine
Study 11770034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22644708 — Safety Biomarker (SAF): Hyaluronic acid
Study 18177922 — Surrogate Endpoint (SUR): Blood pressure
Study 10925684 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1397244 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24444221 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18509970 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16210963 — Surrogate Endpoint (SUR): Serum creatinine
Study 10422019 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7545380 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7545380 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30353743 — Safety Biomarker (SAF): Sodium/hydrogen exchanger 3
Genes: SLC9A3; NHE3
Study 30353743 — Surrogate Endpoint (SUR): Blood pressure
Study 9702614 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 30536129 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 23553154 — Surrogate Endpoint (SUR): Blood pressure
Study 16954359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3132225 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28835238 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 29742746 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28698075 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28698075 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 25573882 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19165198 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17956455 — Surrogate Endpoint (SUR): Serum creatinine
Study 10946808 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8100421 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4