TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01491919 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01491919 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04209634 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study NCT04209634 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04209634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01969578 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03551119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00615485 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02954055 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02954055 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04619628 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04576455 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04576455 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04576455 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01933152 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01933152 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03599713 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT02193191 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04269265 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00467493 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00336063 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT03026777 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01959815 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03049202 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT03049202 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT03049202 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study NCT03489083 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study NCT03172208 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03172208 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT00257543 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00809588 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03583294 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT03599076 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04653714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04653714 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT02918916 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01078532 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03216343 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03235804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03235804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03235804 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03235804 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT03235804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02415114 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT02415114 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00860769 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02695186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02695186 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT00798408 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT00936650 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01274208 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03622983 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01878448 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01878448 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study NCT03962647 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03653546 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03653546 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02515682 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00025922 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04833738 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04176757 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04176757 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04318938 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04354233 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04541927 — Predictive Biomarker (PRD): BCL11B mRNA
Genes: BCL11B; CTIP2; RIT1
Study NCT04190472 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01495013 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02602652 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02908217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02908217 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT02162173 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT03434730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02957019 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01156350 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01156350 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00820118 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03163667 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03163667 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03085290 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01782274 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03340779 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04632615 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03213951 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01489553 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT02232165 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03367117 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01030003 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03834753 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03688035 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02277756 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04243213 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02528591 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03923712 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01555580 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01715870 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04666740 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT03596554 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT03596554 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04623944 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study NCT00174629 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT01400412 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01400412 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03775109 — Safety Biomarker (SAF): Interleukin 1
Study NCT04143646 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00000620 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03595943 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04397172 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05382585 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05382585 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05382585 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT05382585 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT05382585 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT05382585 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study NCT05382585 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study NCT05382585 — Predictive Biomarker (PRD): FAT1 mRNA
Genes: FAT1; CDHF7; FAT
Study NCT01876446 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT01772797 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03265704 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03071497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03638219 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02339051 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00798772 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00798772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00565708 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02943161 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01300858 — Safety Biomarker (SAF): Interleukin 12
Study NCT00555867 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02738619 — Surrogate Endpoint (SUR): Serum calcium
Study NCT00339287 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03409198 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04109300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00003451 — Safety Biomarker (SAF): Interleukin 12
Study NCT01346904 — Predictive Biomarker (PRD): GPSM2 mRNA
Genes: GPSM2; LGN
Study NCT00655655 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02620072 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04330859 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04330859 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT04452955 — Predictive Biomarker (PRD): PTP4A3 mRNA
Genes: PTP4A3; PRL3
Study NCT03804411 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01923038 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT00347971 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study NCT04702503 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT01600651 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT03510689 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01606384 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06368180 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04172220 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT00931229 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03045692 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00802906 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT02758821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01506726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02955290 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02955290 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02404454 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00409656 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03800004 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04242758 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02941055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00280033 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02936323 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study NCT01606241 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT02785744 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01568996 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study NCT01568996 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT02007460 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00125437 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04572672 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02759731 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT00413491 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00413491 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02317419 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT03463681 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03463681 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00302822 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01044069 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03054220 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02704884 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00279058 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00853684 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04358328 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT02567903 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02567903 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01971918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05507047 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT00866762 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT01765413 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01377402 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01377402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02587455 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02587455 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01819038 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03787875 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT01638624 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00440284 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01383863 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT03315507 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04061408 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00422201 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00422201 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01234532 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00385658 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01624636 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01624636 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT01624636 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03729609 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00667121 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01740557 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study NCT01740557 — Predictive Biomarker (PRD): NGFR mRNA
Genes: NGFR; TNFRSF16
Study NCT01740557 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01740557 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT03736005 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT03058874 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02992730 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02992730 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02216890 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study NCT03090165 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03162627 — Safety Biomarker (SAF): RAS pathway
Study NCT03375437 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT03375437 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT03375437 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04569032 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT01969409 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05068583 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02474498 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT00725855 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT00706173 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00619866 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02959346 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT00044733 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT03317873 — Predictive Biomarker (PRD): TMPRSS6 mRNA
Genes: TMPRSS6; UNQ354/PRO618
Study NCT04471727 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study NCT03503773 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04904549 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01380080 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00083499 — Predictive Biomarker (PRD): MYH10 mRNA
Genes: MYH10
Study NCT04076709 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03183024 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT03810807 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03543423 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT03039868 — Predictive Biomarker (PRD): SLC6A14 mRNA
Genes: SLC6A14
Study NCT03913130 — Predictive Biomarker (PRD): CEP290 mRNA
Genes: CEP290; BBS14; KIAA0373; NPHP6
Study NCT00301860 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01844596 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06644521 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT06644521 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06644521 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04610515 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02723955 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study NCT02754011 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02754011 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02046616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04252664 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03469960 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02322099 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02971839 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02989857 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT00938626 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04418245 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04418245 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT05385107 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02171728 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02171728 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02171728 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03781804 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT01505855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03044795 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study NCT03044795 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53