TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27923158 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31657165 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31657165 — Surrogate Endpoint (SUR): Blood pressure
Study 21293921 — Predictive Biomarker (PRD): Hormone receptor
Study 18445665 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 16101937 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16101937 — Safety Biomarker (SAF): Interleukin 12
Study 9740631 — Surrogate Endpoint (SUR): Blood pressure
Study 20303323 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 11591551 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9845852 — Surrogate Endpoint (SUR): Blood pressure
Study 23794693 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 18281378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18281378 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16569732 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 10559084 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17612905 — Surrogate Endpoint (SUR): Blood pressure
Study 7487853 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29659888 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 29659888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29659888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26490018 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18451780 — Surrogate Endpoint (SUR): Urinary oxalate
Study 16170170 — Predictive Biomarker (PRD): Hormone receptor
Study 12952293 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 22732370 — Surrogate Endpoint (SUR): Blood pressure
Study 22732370 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15914614 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 15914614 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 15914614 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15914614 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 15914614 — Predictive Biomarker (PRD): AGTR2 mRNA
Genes: AGTR2
Study 1315652 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 26861939 — Surrogate Endpoint (SUR): Blood pressure
Study 20462041 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 20462041 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20462041 — Surrogate Endpoint (SUR): Blood pressure
Study 12419082 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12419082 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12419082 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28119496 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23283501 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23283501 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 23283501 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 23283501 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 23283501 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 12971730 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18390971 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 14505991 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23628620 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 15188351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15188351 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8521306 — Surrogate Endpoint (SUR): Blood pressure
Study 31387429 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23316894 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1684749 — Surrogate Endpoint (SUR): Blood pressure
Study 24646429 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 10395849 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24217934 — Surrogate Endpoint (SUR): Bone mineral density
Study 8760546 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 29098247 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 29098247 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 8020641 — Surrogate Endpoint (SUR): Blood pressure
Study 24482945 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29127547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29127547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29127547 — Safety Biomarker (SAF): Interleukin 1
Study 9099461 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8402326 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 18544642 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 18544642 — Predictive Biomarker (PRD): PPP1R15A mRNA
Genes: PPP1R15A; GADD34
Study 18544642 — Predictive Biomarker (PRD): EIF2AK3 mRNA
Genes: EIF2AK3; PEK; PERK
Study 18544642 — Predictive Biomarker (PRD): XBP1 mRNA
Genes: XBP1; TREB5; XBP2
Study 12742468 — Surrogate Endpoint (SUR): Serum creatinine
Study 12742468 — Surrogate Endpoint (SUR): Serum uric acid
Study 9090787 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9090787 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 9090787 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27552061 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 7705152 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31257407 — Surrogate Endpoint (SUR): Blood pressure
Study 23392989 — Predictive Biomarker (PRD): MECP2 mRNA
Genes: MECP2
Study 23392989 — Predictive Biomarker (PRD): ACSM3 mRNA
Genes: ACSM3; SAH
Study 3297772 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22027646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11834237 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9568181 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8309029 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8309029 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29614865 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3890872 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 3890872 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3890872 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 15604153 — Predictive Biomarker (PRD): TBX21 mRNA
Genes: TBX21; TBET; TBLYM
Study 7962327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23698747 — Predictive Biomarker (PRD): TAP1 mRNA
Genes: TAP1; ABCB2; PSF1; RING4; Y3
Study 19881358 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 16640105 — Monitoring Biomarker (MOI): HBV DNA
Study 9196087 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 6423796 — Surrogate Endpoint (SUR): Plasma ammonia
Study 25819980 — Surrogate Endpoint (SUR): Blood pressure
Study 23183514 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23183514 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 10432174 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8562738 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22113223 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16762960 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 16762960 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16762960 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 16762960 — Safety Biomarker (SAF): Reactive oxygen species
Study 31894030 — Surrogate Endpoint (SUR): Blood pressure
Study 31894030 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21194693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21194693 — Surrogate Endpoint (SUR): Blood pressure
Study 13678475 — Surrogate Endpoint (SUR): Bone mineral density
Study 30266120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30266120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30266120 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24142752 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22324419 — Surrogate Endpoint (SUR): Blood pressure
Study 19678781 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19678781 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7014105 — Surrogate Endpoint (SUR): Blood pressure
Study 31475696 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 28091647 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23695232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15296473 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15296473 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10924298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23275042 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 23275042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23275042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14650364 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8885912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29467335 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24758417 — Surrogate Endpoint (SUR): Blood pressure
Study 20626209 — Surrogate Endpoint (SUR): Serum creatinine
Study 31575509 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 31575509 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21484037 — Surrogate Endpoint (SUR): Blood pressure
Study 19466963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15545348 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15545348 — Surrogate Endpoint (SUR): Blood pressure
Study 24634205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8385525 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8385525 — Surrogate Endpoint (SUR): Blood pressure
Study 25231730 — Surrogate Endpoint (SUR): Bone mineral density
Study 19520690 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 14963719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11888583 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10207641 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 9552949 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9552949 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26231305 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 16645234 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 16645234 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6086866 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30922731 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 1981019 — Surrogate Endpoint (SUR): Blood pressure
Study 16824149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 16824149 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24726166 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 18753099 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18753099 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18753099 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15133864 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 15133864 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 3284341 — Surrogate Endpoint (SUR): Blood pressure
Study 28480984 — Safety Biomarker (SAF): Hyaluronic acid
Study 26609122 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 24384734 — Surrogate Endpoint (SUR): Blood pressure
Study 16966688 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11103113 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11103113 — Surrogate Endpoint (SUR): Blood pressure
Study 11517472 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28054902 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28054902 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8694619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8694619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19384168 — Surrogate Endpoint (SUR): Serum creatinine
Study 12147313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12147313 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11192234 — Surrogate Endpoint (SUR): Serum potassium
Study 12013486 — Surrogate Endpoint (SUR): Blood pressure
Study 22710821 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22710821 — Safety Biomarker (SAF): Reactive oxygen species
Study 15905733 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15905733 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28487911 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18339561 — Safety Biomarker (SAF): Hyaluronic acid
Study 1786194 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 30083727 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30083727 — Surrogate Endpoint (SUR): Blood pressure
Study 10972367 — Surrogate Endpoint (SUR): Blood pressure
Study 8849401 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 8849401 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 23842856 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 23842856 — Predictive Biomarker (PRD): UGT2B15 mRNA
Genes: UGT2B15; UGT2B8
Study 23842856 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21623000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20047115 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 20047115 — Surrogate Endpoint (SUR): Serum creatinine
Study 20047115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23054851 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17146393 — Predictive Biomarker (PRD): GJB2 mRNA
Genes: GJB2
Study 17146393 — Predictive Biomarker (PRD): SLC26A4 mRNA
Genes: SLC26A4; PDS
Study 12665988 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 29325772 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 29325772 — Surrogate Endpoint (SUR): Blood pressure
Study 12370998 — Predictive Biomarker (PRD): RGMA mRNA
Genes: RGMA; RGM
Study 23901280 — Surrogate Endpoint (SUR): Blood pressure
Study 10430109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10430109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10430109 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17192686 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 14571187 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14571187 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1598311 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27529226 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16192765 — Surrogate Endpoint (SUR): Blood pressure
Study 12548534 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10411363 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10411363 — Surrogate Endpoint (SUR): Blood pressure
Study 15728225 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 15728225 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 3896099 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23380890 — Surrogate Endpoint (SUR): Blood pressure
Study 12065742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10404085 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17158411 — Surrogate Endpoint (SUR): Blood pressure
Study 17158411 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17158411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17158411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6327800 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3409855 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10596714 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22828460 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21060068 — Surrogate Endpoint (SUR): Blood pressure
Study 21060068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21060068 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12479191 — Surrogate Endpoint (SUR): Blood pressure
Study 25513788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17426465 — Safety Biomarker (SAF): Reactive oxygen species
Study 2523663 — Surrogate Endpoint (SUR): Blood pressure
Study 24029572 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19736165 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 29685815 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 20865877 — Surrogate Endpoint (SUR): Blood pressure
Study 31981323 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25211364 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19762737 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 11795353 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11795353 — Surrogate Endpoint (SUR): Bone mineral density
Study 26504195 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 26504195 — Predictive Biomarker (PRD): GNPDA2 mRNA
Genes: GNPDA2; GNP2
Study 26504195 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22166652 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 11557312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11557312 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7852661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12538743 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9123730 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8349185 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8349185 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31539292 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 26345106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26345106 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19103540 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24019110 — Surrogate Endpoint (SUR): Blood pressure
Study 20087302 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2410683 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23876559 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31705466 — Surrogate Endpoint (SUR): Blood pressure
Study 24197584 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20715906 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15588139 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 15588139 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15588139 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29885390 — Predictive Biomarker (PRD): HR mRNA
Genes: HR