TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19327603 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19327603 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18614721 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15824925 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 30601319 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9258888 — Surrogate Endpoint (SUR): Blood pressure
Study 8488820 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 25572279 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 16183188 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16183188 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15169798 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 3306289 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21951314 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 21951314 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28989140 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 26280247 — Surrogate Endpoint (SUR): Blood pressure
Study 24074738 — Predictive Biomarker (PRD): DDO mRNA
Genes: DDO
Study 17368881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17368881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17368881 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2898717 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 2898717 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31980022 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31980022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31980022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25602854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25602854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25602854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19388074 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8527004 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8527004 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 2054690 — Surrogate Endpoint (SUR): Blood pressure
Study 24617449 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10834505 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 31624844 — Predictive Biomarker (PRD): SH2B3 mRNA
Genes: SH2B3; LNK
Study 31624844 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31624844 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31624844 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 1391062 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12369732 — Surrogate Endpoint (SUR): Blood pressure
Study 30202902 — Predictive Biomarker (PRD): FFAR4 mRNA
Genes: FFAR4; GPR120; GPR129; O3FAR1; PGR4
Study 25283139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8470789 — Surrogate Endpoint (SUR): Blood pressure
Study 2951261 — Surrogate Endpoint (SUR): Blood pressure
Study 22197217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22197217 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22197217 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11124745 — Surrogate Endpoint (SUR): Blood pressure
Study 25662105 — Surrogate Endpoint (SUR): Blood pressure
Study 1316307 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1316307 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 31357949 — Predictive Biomarker (PRD): ANKS4B mRNA
Genes: ANKS4B; HARP
Study 29316236 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17391324 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 17391324 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 14966345 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9639377 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 24283172 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 18462083 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 8960948 — Surrogate Endpoint (SUR): Blood pressure
Study 28689679 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 25496464 — Surrogate Endpoint (SUR): Serum creatinine
Study 25496464 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19631946 — Surrogate Endpoint (SUR): Blood pressure
Study 9716583 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3230200 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30482460 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19917874 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12039398 — Surrogate Endpoint (SUR): Blood pressure
Study 8607618 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 30545701 — Surrogate Endpoint (SUR): Blood pressure
Study 25682576 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 8424510 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 27281019 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 27281019 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 27281019 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 19420283 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 19420283 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19420283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16883525 — Predictive Biomarker (PRD): CDX2 mRNA
Genes: CDX2; CDX3
Study 16883525 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 16883525 — Surrogate Endpoint (SUR): Bone mineral density
Study 7515652 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28678568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28678568 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28678568 — Safety Biomarker (SAF): Interleukin 1
Study 24916786 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 12798752 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25464675 — Surrogate Endpoint (SUR): Blood pressure
Study 20167156 — Surrogate Endpoint (SUR): Blood pressure
Study 25869509 — Surrogate Endpoint (SUR): Blood pressure
Study 16308413 — Surrogate Endpoint (SUR): Blood pressure
Study 9532517 — Surrogate Endpoint (SUR): Blood pressure
Study 8300487 — Surrogate Endpoint (SUR): Blood pressure
Study 31870942 — Surrogate Endpoint (SUR): Blood pressure
Study 18981372 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 24385236 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24385236 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24385236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16015004 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16015004 — Surrogate Endpoint (SUR): Blood pressure
Study 16015004 — Surrogate Endpoint (SUR): Serum creatinine
Study 12359651 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 1467074 — Surrogate Endpoint (SUR): Serum creatinine
Study 29508715 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24389416 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24389416 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24389416 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22878803 — Surrogate Endpoint (SUR): Blood pressure
Study 20230461 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 8996294 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8996294 — Surrogate Endpoint (SUR): Blood pressure
Study 21321419 — Monitoring Biomarker (MOI): HBV DNA
Study 19301059 — Surrogate Endpoint (SUR): Blood pressure
Study 30679439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30679439 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 30679439 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 1290169 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29494727 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21415158 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 19480671 — Surrogate Endpoint (SUR): Blood pressure
Study 9071430 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2464358 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 12708879 — Surrogate Endpoint (SUR): Blood pressure
Study 31683942 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 20153900 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 394062 — Surrogate Endpoint (SUR): Blood pressure
Study 21443321 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 7683553 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3333522 — Surrogate Endpoint (SUR): Blood pressure
Study 26916794 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 26916794 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22218160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22218160 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 19949851 — Surrogate Endpoint (SUR): Blood pressure
Study 10653831 — Surrogate Endpoint (SUR): Blood pressure
Study 8842352 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8842352 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31136218 — Predictive Biomarker (PRD): DNM1L mRNA
Genes: DNM1L; DLP1; DRP1
Study 31136218 — Predictive Biomarker (PRD): SLC25A4 mRNA
Genes: SLC25A4; AAC1; ANT1
Study 27603149 — Safety Biomarker (SAF): Hyaluronic acid
Study 27603149 — Monitoring Biomarker (MOI): HBV DNA
Study 22017999 — Predictive Biomarker (PRD): RTN1 mRNA
Genes: RTN1; NSP
Study 15481160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29073629 — Surrogate Endpoint (SUR): Blood pressure
Study 20029516 — Surrogate Endpoint (SUR): Blood pressure
Study 16304572 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 822857 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26416895 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 26416895 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21523716 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 16713529 — Surrogate Endpoint (SUR): Blood pressure
Study 11146520 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25141922 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 2856710 — Surrogate Endpoint (SUR): Blood pressure
Study 30888598 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30888598 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21437603 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 16541115 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 1600704 — Surrogate Endpoint (SUR): Blood pressure
Study 20560409 — Surrogate Endpoint (SUR): Blood pressure
Study 16916339 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 158003 — Surrogate Endpoint (SUR): Bacterial count
Study 31350270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7816518 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 1669517 — Surrogate Endpoint (SUR): Blood pressure
Study 6762807 — Surrogate Endpoint (SUR): Serum creatinine
Study 6762807 — Surrogate Endpoint (SUR): Serum sodium
Study 6762807 — Surrogate Endpoint (SUR): Serum uric acid
Study 31585544 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19397224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19397224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19397224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16856571 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23328000 — Surrogate Endpoint (SUR): Blood pressure
Study 23328000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11758626 — Surrogate Endpoint (SUR): Blood pressure
Study 9237086 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9237086 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 28206674 — Predictive Biomarker (PRD): NR4A1 mRNA
Genes: NR4A1; GFRP1; HMR; NAK1
Study 25898052 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12499977 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12499977 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8672752 — Surrogate Endpoint (SUR): Serum creatinine
Study 8672752 — Surrogate Endpoint (SUR): Serum potassium
Study 29848902 — Surrogate Endpoint (SUR): Blood pressure
Study 29848902 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29848902 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25237981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25237981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17700333 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 12153969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12153969 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10915394 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10915394 — Surrogate Endpoint (SUR): Blood pressure
Study 10915394 — Surrogate Endpoint (SUR): Serum uric acid
Study 2370014 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28452195 — Surrogate Endpoint (SUR): Blood pressure
Study 25485803 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 28741272 — Surrogate Endpoint (SUR): Blood pressure
Study 26034004 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23349254 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23349254 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17186970 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26323735 — Surrogate Endpoint (SUR): Blood pressure
Study 21711463 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21711463 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 19419855 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24083754 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18366084 — Predictive Biomarker (PRD): SFPQ mRNA
Genes: SFPQ; PSF
Study 23116683 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 12746781 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25237 — Surrogate Endpoint (SUR): Blood pressure
Study 9387966 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22326841 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 22326841 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 12428223 — Safety Biomarker (SAF): Interleukin 1
Study 27467969 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18316422 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 10651230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 27112532 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 27112532 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 22036871 — Surrogate Endpoint (SUR): Blood pressure
Study 11895063 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11895063 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23458257 — Surrogate Endpoint (SUR): Blood pressure
Study 18387444 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 16631617 — Surrogate Endpoint (SUR): Blood pressure
Study 31551204 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31551204 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24495849 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 16943848 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15827103 — Surrogate Endpoint (SUR): Blood pressure
Study 30453910 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 30453910 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 26195001 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23824463 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 23824463 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23824463 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21161463 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16192577 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9468205 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27140800 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21810677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17268417 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17268417 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9457393 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30134549 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 30134549 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 30134549 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 30134549 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20105396 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 22269590 — Surrogate Endpoint (SUR): Blood pressure
Study 22269590 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9129563 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30561227 — Surrogate Endpoint (SUR): Blood pressure
Study 29967525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10551192 — Surrogate Endpoint (SUR): Blood pressure
Study 30068817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26843796 — Surrogate Endpoint (SUR): Blood pressure
Study 24484726 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 19606092 — Predictive Biomarker (PRD): RAB8A mRNA
Genes: RAB8A; MEL; RAB8
Study 17697058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17697058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15353873 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15353873 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11593101 — Surrogate Endpoint (SUR): Blood pressure
Study 14632537 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1444872 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 1444872 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24286335 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 11109505 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9122904 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27659741 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18438853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16290232 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16290232 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 16290232 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 11045316 — Surrogate Endpoint (SUR): Serum calcium
Study 9363869 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1607916 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3769194 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16151471 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 9569080 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31756059 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 22309046 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 8551492 — Surrogate Endpoint (SUR): Blood pressure
Study 396063 — Surrogate Endpoint (SUR): Blood pressure
Study 17461981 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15465744 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 8010332 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8010332 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21057823 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 7664428 — Surrogate Endpoint (SUR): Blood pressure
Study 23395281 — Surrogate Endpoint (SUR): Serum uric acid
Study 23395281 — Surrogate Endpoint (SUR): Serum creatinine
Study 23395281 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31138727 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31138727 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 31138727 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden