TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18991814 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15520832 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 8845036 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 29465890 — Surrogate Endpoint (SUR): Blood pressure
Study 20451687 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9362378 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3777458 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11915784 — Safety Biomarker (SAF): IL-6 and IL-10
Study 27588816 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27588816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30777131 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 30777131 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30777131 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30101539 — Surrogate Endpoint (SUR): Bone mineral density
Study 17432678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17432678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14571614 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 8804239 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 16033855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16033855 — Surrogate Endpoint (SUR): Serum calcium
Study 12241539 — Surrogate Endpoint (SUR): Blood pressure
Study 3188983 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3188983 — Surrogate Endpoint (SUR): Blood pressure
Study 30846389 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 30846389 — Surrogate Endpoint (SUR): Blood pressure
Study 25239484 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9808483 — Surrogate Endpoint (SUR): Bone mineral density
Study 9808483 — Surrogate Endpoint (SUR): Serum calcium
Study 17689883 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9581695 — Monitoring Biomarker (MOI): HBV DNA
Study 8114857 — Surrogate Endpoint (SUR): Blood pressure
Study 26071796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23924691 — Surrogate Endpoint (SUR): Blood pressure
Study 23924691 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23924691 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16946104 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 16946104 — Predictive Biomarker (PRD): BLNK mRNA
Genes: BLNK; BASH; SLP65
Study 16946104 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 8933645 — Surrogate Endpoint (SUR): Blood pressure
Study 8933645 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31079567 — Surrogate Endpoint (SUR): Bone mineral density
Study 27134133 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27134133 — Safety Biomarker (SAF): BDNF
Study 31678185 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23034540 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23034540 — Surrogate Endpoint (SUR): Blood pressure
Study 16023759 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 16023759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29668325 — Surrogate Endpoint (SUR): Blood pressure
Study 28190761 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28190761 — Predictive Biomarker (PRD): Hormone receptor
Study 25800686 — Predictive Biomarker (PRD): OSCAR mRNA
Genes: OSCAR
Study 23859929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8676798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24652410 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22328739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21049175 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 31083000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19183462 — Surrogate Endpoint (SUR): Blood pressure
Study 4061524 — Surrogate Endpoint (SUR): Blood pressure
Study 30529244 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 12119223 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23632659 — Surrogate Endpoint (SUR): Bone mineral density
Study 19025429 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 16557033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29562806 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 1932649 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24947656 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 24036618 — Surrogate Endpoint (SUR): Blood pressure
Study 21358291 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 21358291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 11684346 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 28360187 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 23899048 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 24423928 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 16914460 — Surrogate Endpoint (SUR): Blood pressure
Study 9760806 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9760806 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 21923696 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22104346 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 14720054 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7772354 — Surrogate Endpoint (SUR): Blood pressure
Study 2306747 — Surrogate Endpoint (SUR): Blood pressure
Study 30502442 — Surrogate Endpoint (SUR): Blood pressure
Study 20634174 — Surrogate Endpoint (SUR): Blood pressure
Study 20634174 — Safety Biomarker (SAF): Urinary microalbumin
Study 9292761 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 8424304 — Surrogate Endpoint (SUR): Blood pressure
Study 24036849 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24036849 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 24036849 — Safety Biomarker (SAF): BDNF
Study 24036849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18032491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 18032491 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8350886 — Surrogate Endpoint (SUR): Blood pressure
Study 19066291 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8581408 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 8581408 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27624149 — Surrogate Endpoint (SUR): Blood pressure
Study 23396354 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 23396354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23396354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26602300 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 28872920 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25568568 — Surrogate Endpoint (SUR): Blood pressure
Study 7509329 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 19037200 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 24472633 — Surrogate Endpoint (SUR): Blood pressure
Study 18714239 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 4027151 — Surrogate Endpoint (SUR): Blood pressure
Study 31416212 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25602164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24851570 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24851570 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20847731 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 15860518 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15860518 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 12679453 — Surrogate Endpoint (SUR): Bone mineral density
Study 29044032 — Surrogate Endpoint (SUR): Blood pressure
Study 29044032 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29044032 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8874564 — Surrogate Endpoint (SUR): Blood pressure
Study 17950147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18580347 — Surrogate Endpoint (SUR): Blood pressure
Study 1771224 — Surrogate Endpoint (SUR): Blood pressure
Study 30579806 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30579806 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25834412 — Surrogate Endpoint (SUR): Bone mineral density
Study 21419745 — Surrogate Endpoint (SUR): Blood pressure
Study 21419745 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17723086 — Surrogate Endpoint (SUR): Blood pressure
Study 19827650 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26252316 — Surrogate Endpoint (SUR): Blood pressure
Study 23902673 — Surrogate Endpoint (SUR): Blood pressure
Study 8377448 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 3017033 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3017033 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 3017033 — Surrogate Endpoint (SUR): Blood pressure
Study 31810893 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 21499794 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30720004 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30720004 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25182660 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 25182660 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 25182660 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 16799799 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 29275583 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29275583 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 25171115 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 23919441 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23919441 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23919441 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21701083 — Surrogate Endpoint (SUR): Blood pressure
Study 18307781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18307781 — Surrogate Endpoint (SUR): Blood pressure
Study 28485264 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28485264 — Surrogate Endpoint (SUR): Blood pressure
Study 25472864 — Surrogate Endpoint (SUR): Serum sodium
Study 22537843 — Surrogate Endpoint (SUR): Blood pressure
Study 2181841 — Surrogate Endpoint (SUR): Blood pressure
Study 31837008 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 1602945 — Surrogate Endpoint (SUR): Blood pressure
Study 22301066 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10450299 — Surrogate Endpoint (SUR): Blood pressure
Study 25239849 — Surrogate Endpoint (SUR): Bone mineral density
Study 11933550 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30016393 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 15071276 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2262216 — Surrogate Endpoint (SUR): Blood pressure
Study 2262216 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 377932 — Surrogate Endpoint (SUR): Blood pressure
Study 26615376 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 17983379 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9456999 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28780222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26188020 — Surrogate Endpoint (SUR): Blood pressure
Study 21969502 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 18335584 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 15589194 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 26421385 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20818716 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 20818716 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 20818716 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17666475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17666475 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7865162 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 7046900 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 24760536 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 24760536 — Predictive Biomarker (PRD): PRKAA2 mRNA
Genes: PRKAA2; AMPK; AMPK2
Study 24760536 — Predictive Biomarker (PRD): PRKAG3 mRNA
Genes: PRKAG3; AMPKG3
Study 24760536 — Predictive Biomarker (PRD): NDUFS1 mRNA
Genes: NDUFS1
Study 24760536 — Predictive Biomarker (PRD): SDHA mRNA
Genes: SDHA; SDH2; SDHF
Study 24760536 — Predictive Biomarker (PRD): UQCRC1 mRNA
Genes: UQCRC1
Study 24760536 — Predictive Biomarker (PRD): COX5B mRNA
Genes: COX5B
Study 24760536 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 24760536 — Predictive Biomarker (PRD): CPT1B mRNA
Genes: CPT1B; KIAA1670
Study 24760536 — Predictive Biomarker (PRD): HADH mRNA
Genes: HADH; HAD; HAD1; HADHSC; SCHAD
Study 10096255 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29458401 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 29458401 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 22738299 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 20088810 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18564199 — Surrogate Endpoint (SUR): Blood pressure
Study 1604872 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 16390760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10725861 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 1623678 — Predictive Biomarker (PRD): PDP1 mRNA
Genes: PDP1; PDP; PPM2C
Study 31046521 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29755598 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 14560766 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30349198 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 27069169 — Safety Biomarker (SAF): PPOX
Genes: HCRT; OX
Study 24008819 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23872591 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23872591 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17143000 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17143000 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17143000 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12809171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19373973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14746532 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 2204594 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 24502766 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 24502766 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 10048900 — Surrogate Endpoint (SUR): Serum testosterone
Study 26220734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26220734 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 19671303 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 19671303 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19671303 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 9581727 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 7994817 — Surrogate Endpoint (SUR): Blood pressure
Study 12846625 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 6492943 — Surrogate Endpoint (SUR): Blood pressure
Study 6492943 — Surrogate Endpoint (SUR): Serum potassium
Study 30206110 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 30206110 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30206110 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17707382 — Predictive Biomarker (PRD): P2RY12 mRNA
Genes: P2RY12; HORK3
Study 31987371 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31987371 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 31987371 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28425253 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 28425253 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21760636 — Surrogate Endpoint (SUR): Blood pressure
Study 9269759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9269759 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 9269759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26438518 — Surrogate Endpoint (SUR): Bone mineral density
Study 28579423 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 15085362 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 23159547 — Surrogate Endpoint (SUR): Blood pressure
Study 9756242 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2693499 — Surrogate Endpoint (SUR): Blood pressure
Study 27974308 — Surrogate Endpoint (SUR): Blood pressure
Study 24002121 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24002121 — Surrogate Endpoint (SUR): Blood pressure
Study 24002121 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10779449 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 8622077 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22318492 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22318492 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11410120 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 29660936 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12829890 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 12829890 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9048263 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25766724 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 25766724 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 12360152 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7538547 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30316907 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 26822324 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23597077 — Predictive Biomarker (PRD): ENPP2 mRNA
Genes: ENPP2; ATX; PDNP2
Study 22333484 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 8784096 — Surrogate Endpoint (SUR): Bone mineral density
Study 25599737 — Surrogate Endpoint (SUR): Bone mineral density
Study 8865524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6090020 — Surrogate Endpoint (SUR): Serum creatinine
Study 8370371 — Surrogate Endpoint (SUR): Blood pressure
Study 22561357 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19886384 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15064097 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15064097 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 23726433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23726433 — Safety Biomarker (SAF): IL-6 and IL-10
Study 29141241 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 29141241 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24646100 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8813039 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6399927 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 30188798 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T