TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01917279 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00895479 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01288300 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01288300 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00831220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03086694 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00824785 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00824785 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04969562 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03625258 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT03625258 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03562182 — Predictive Biomarker (PRD): LPCAT1 mRNA
Genes: LPCAT1; AYTL2; PFAAP3
Study NCT02722798 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02621190 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01663662 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05311072 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02349672 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT01189656 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03259165 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00736190 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03065751 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT01694758 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04200833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04391829 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00844974 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00844974 — Safety Biomarker (SAF): BDNF
Study NCT00903292 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00991796 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT01852799 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT01852799 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00258687 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00558402 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00072111 — Safety Biomarker (SAF): Interleukin 1
Study NCT03669731 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02236000 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01891032 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04224584 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT04224584 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study NCT02230267 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02230267 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00166634 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02011828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00845130 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01041547 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00950300 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03917758 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03917758 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00365053 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT00112437 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03513211 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03878550 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT04604938 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01510405 — Predictive Biomarker (PRD): PLK1 mRNA
Genes: PLK1; PLK
Study NCT01510405 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT00942916 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT02873975 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study NCT02873975 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02873975 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCNE1 mRNA
Genes: CCNE1; CCNE
Study NCT00794664 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04198935 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04198935 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04198935 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01372930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02167594 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03986463 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01215383 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study NCT01215383 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study NCT01215383 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02271035 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02118324 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01947738 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study NCT00107263 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03567551 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT01939990 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00327587 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00001469 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT00109057 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00155649 — Predictive Biomarker (PRD): NOTCH4 mRNA
Genes: NOTCH4; INT3
Study NCT00155649 — Predictive Biomarker (PRD): DISC1 mRNA
Genes: DISC1; KIAA0457
Study NCT00155649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00155649 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT00595348 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00688844 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00688844 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study NCT00185120 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00185120 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01834027 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03516565 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT03786705 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02229084 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02229084 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01224561 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT04172480 — Predictive Biomarker (PRD): MPHOSPH8 mRNA
Genes: MPHOSPH8; MPP8
Study NCT04797936 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00001763 — Safety Biomarker (SAF): Interleukin 12
Study NCT00001763 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04322513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01204138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00685854 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00685854 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00772408 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study NCT00059423 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00059423 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02004769 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00901719 — Predictive Biomarker (PRD): APLNR mRNA
Genes: APLNR; AGTRL1; APJ
Study NCT01283763 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01192087 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01192087 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00746928 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00948480 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01507662 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03922750 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03922750 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02344849 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01216020 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01019356 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01951209 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study NCT00580190 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT00580190 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT06516172 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01116791 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01116791 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01607970 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study NCT00433745 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT00812630 — Predictive Biomarker (PRD): MENT mRNA
Genes: MENT; C1orf56; UNQ547/PRO1104
Study NCT00812630 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04612309 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04612309 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04612309 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT01625403 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02414282 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01622764 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01622764 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01167023 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01271647 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01312506 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04163094 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01828112 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01827280 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01243151 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01243151 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04054258 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02994836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03021876 — Predictive Biomarker (PRD): SIRT3 mRNA
Genes: SIRT3; SIR2L3
Study NCT01378962 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01378962 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01736839 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01736839 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00421863 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03317080 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04013763 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03093363 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00646984 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00646984 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04348422 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00884819 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02364258 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study NCT01887795 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01749085 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00162929 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04228484 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00165152 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00165152 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04731324 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04731324 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study NCT03699150 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01719549 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT01719549 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT02169440 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00540358 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00540358 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT00540358 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02364869 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT02364869 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00385736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02818751 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02337322 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04345822 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02123823 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02123823 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01282086 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01924286 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00236002 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04152356 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT04463953 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01650857 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT01317147 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study NCT00157521 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02528019 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02528019 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00432952 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02046122 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT00397657 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04314661 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00579358 — Predictive Biomarker (PRD): TBX5 mRNA
Genes: TBX5
Study NCT00579358 — Predictive Biomarker (PRD): GATA4 mRNA
Genes: GATA4
Study NCT02093728 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02093728 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03985657 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04402892 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00525330 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03396354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01965327 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT01965327 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00990574 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03174158 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT00785603 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01720953 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01720953 — Safety Biomarker (SAF): BDNF
Study NCT05909605 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04606888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04606888 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT05021276 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00521508 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00664196 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00481169 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01781117 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02336633 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03425461 — Predictive Biomarker (PRD): SEMA4D mRNA
Genes: SEMA4D; C9orf164; CD100; SEMAJ
Study NCT00834353 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study NCT01165060 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT03492567 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03492567 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT05049200 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00668395 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT04459754 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT03637127 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00860262 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02417571 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01806272 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01806272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02810223 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT04007835 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04007835 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00088608 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT03366428 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03050866 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01756313 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT04210544 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT04210544 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT04210544 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04210544 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02233751 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02002130 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00160524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00418834 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02435433 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT01219140 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03973151 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT03792139 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00662896 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04188964 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03041324 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study NCT00564031 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04392596 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01994213 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01994213 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01994213 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study NCT03709784 — Predictive Biomarker (PRD): Chromosome 5q
Study NCT02305407 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study NCT01724762 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04381741 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04381741 — Predictive Biomarker (PRD): IL7 mRNA
Genes: IL7
Study NCT04381741 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study NCT04381741 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04381741 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03292263 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01346865 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT01015963 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study NCT00085501 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00085501 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF