TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04992156 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03142919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03142919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03003637 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT01730612 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01730612 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03802708 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT05754476 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT00989183 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04240106 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04240106 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04240106 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT04224922 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT00761982 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01361217 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01361217 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01361217 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01361217 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01518387 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03291106 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study NCT03291106 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT03291106 — Predictive Biomarker (PRD): EPCAM mRNA
Genes: EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Study NCT03291106 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04709120 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04679571 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03345303 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT04176393 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT01348035 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT01348035 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT01890265 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03929666 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03091088 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00346684 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02235272 — Predictive Biomarker (PRD): XG mRNA
Genes: XG; PBDX
Study NCT03270358 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT03009864 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00898846 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT01263002 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04239586 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study NCT04239586 — Predictive Biomarker (PRD): HNF4A mRNA
Genes: HNF4A; HNF4; NR2A1; TCF14
Study NCT04239586 — Predictive Biomarker (PRD): HNF1B mRNA
Genes: HNF1B; TCF2
Study NCT00291824 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03948997 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03666988 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study NCT01170234 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT04369456 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03573063 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04824014 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03262805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00330369 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04346511 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03637283 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00092274 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00005407 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03549286 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04602143 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study NCT02499627 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00925002 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT03727035 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT00003432 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00259844 — Predictive Biomarker (PRD): TPBG mRNA
Genes: TPBG; 5T4
Study NCT01760265 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01883700 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00263003 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00881985 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03216538 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03293498 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01179334 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01179334 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02115139 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03133117 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03666403 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study NCT02281838 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04504916 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04504916 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00891436 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT02776969 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study NCT00390299 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT05060692 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT02751138 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT02751138 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02751138 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01750866 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03856359 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03856359 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT03856359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03856359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01359436 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02982655 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00341809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02359370 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01005524 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT01670422 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05225883 — Predictive Biomarker (PRD): LGI1 mRNA
Genes: LGI1; EPT; UNQ775/PRO1569
Study NCT02601170 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03858348 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT03919292 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01038011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03005678 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02043054 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02299375 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02299375 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02550691 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT02058017 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT00111085 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT01115959 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02309034 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03473340 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00593697 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04756323 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04756323 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01560416 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03897127 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study NCT01037998 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01037998 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01152788 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study NCT02515838 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02206763 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02206763 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02448147 — Predictive Biomarker (PRD): SLC5A8 mRNA
Genes: SLC5A8; AIT; SMCT; SMCT1
Study NCT02861287 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03706261 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00001730 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT03767465 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04035668 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00710892 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study NCT01129232 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02565069 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study NCT02447380 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02329132 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02860286 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study NCT03022123 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT00650663 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01799343 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02357199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01907607 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT01907607 — Predictive Biomarker (PRD): CDKN2B mRNA
Genes: CDKN2B; MTS2
Study NCT01907607 — Predictive Biomarker (PRD): MTAP mRNA
Genes: MTAP; MSAP
Study NCT01907607 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study NCT01907607 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04088799 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT04088799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02484443 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03816722 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00457847 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT01318382 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT02772263 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00030238 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02746328 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT05948644 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05015647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01718158 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT01900834 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00654316 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00044863 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04262479 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00507689 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02442895 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02957981 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02957981 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02863900 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02863900 — Predictive Biomarker (PRD): GSTA1 mRNA
Genes: GSTA1
Study NCT02863900 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study NCT04412018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04412018 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT00523107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00762879 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02120911 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02080650 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00420901 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT03842488 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03842488 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT02779868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01308840 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03360240 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02242058 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01472003 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01472003 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01503814 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04107402 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT00396513 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00971789 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT00837278 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01434901 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00585533 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05141838 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00463788 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02534311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02634970 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03653442 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00742300 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03449849 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT03449849 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study NCT02406521 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04244071 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03552107 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02163577 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04086966 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01343745 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02403024 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03410069 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02250872 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02250872 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02250872 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01716364 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02817178 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT02817178 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00194714 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03281382 — Safety Biomarker (SAF): Interleukin 12
Study NCT01144143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00753948 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03349255 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT00506779 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02695914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02695914 — Safety Biomarker (SAF): Interleukin 1
Study NCT02695914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03371199 — Surrogate Endpoint (SUR): Serum sodium
Study NCT02232971 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03531814 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01849315 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01361945 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01644513 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01644513 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01291381 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03162133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03162133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03162133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00460408 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00865124 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03013504 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00572286 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study NCT02868268 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04053816 — Surrogate Endpoint (SUR): Serum potassium
Study NCT00222144 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT04061109 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT00718848 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03803605 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03762434 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00596648 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00596648 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00596648 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT00596648 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02577419 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study NCT03251768 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02663336 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02251496 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01541865 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02598596 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03141255 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study NCT04254146 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00903422 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00958477 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT00580112 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00580112 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00580112 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03812575 — Predictive Biomarker (PRD): Exhaled nitric oxide