TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24374394 — Surrogate Endpoint (SUR): Blood pressure
Study 17086465 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31696603 — Surrogate Endpoint (SUR): Blood pressure
Study 30649270 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 28520768 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19798072 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 10344062 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10344062 — Surrogate Endpoint (SUR): Blood pressure
Study 27580151 — Surrogate Endpoint (SUR): Bone mineral density
Study 20881846 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 11215556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9024252 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9024252 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15890758 — Surrogate Endpoint (SUR): Blood pressure
Study 6085004 — Surrogate Endpoint (SUR): Blood pressure
Study 20493549 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20493549 — Surrogate Endpoint (SUR): Blood pressure
Study 2505712 — Surrogate Endpoint (SUR): Blood pressure
Study 2505712 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 335203 — Surrogate Endpoint (SUR): Blood pressure
Study 29446817 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 19081418 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19081418 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8942424 — Predictive Biomarker (PRD): SLC26A3 mRNA
Genes: SLC26A3; DRA
Study 29324776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29324776 — Surrogate Endpoint (SUR): Blood pressure
Study 10094216 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2134116 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30368018 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 24804272 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10784382 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26963724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26963724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19258384 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19258384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19258384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15308521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11355895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9743816 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 11336165 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26970723 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 16766587 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10404768 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 10404768 — Surrogate Endpoint (SUR): Blood pressure
Study 26200164 — Surrogate Endpoint (SUR): Bone mineral density
Study 17164979 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study 3627579 — Surrogate Endpoint (SUR): Blood pressure
Study 31919539 — Surrogate Endpoint (SUR): Blood pressure
Study 26378118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19172341 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 27545848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23060506 — Predictive Biomarker (PRD): STT3A mRNA
Genes: STT3A; ITM1; TMC
Study 2822334 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27450392 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27450392 — Surrogate Endpoint (SUR): Blood pressure
Study 16970100 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 11854874 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25900353 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11491421 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7625111 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22959905 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10595696 — Surrogate Endpoint (SUR): Blood pressure
Study 2982491 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30962094 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17920338 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12842242 — Surrogate Endpoint (SUR): Blood pressure
Study 12842242 — Surrogate Endpoint (SUR): Serum potassium
Study 30677788 — Predictive Biomarker (PRD): BMP6 mRNA
Genes: BMP6; VGR
Study 10569656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10569656 — Surrogate Endpoint (SUR): Blood pressure
Study 10569656 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6856646 — Surrogate Endpoint (SUR): Blood pressure
Study 27488327 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27488327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11789207 — Surrogate Endpoint (SUR): Blood pressure
Study 10937982 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31943768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7664216 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1071694 — Surrogate Endpoint (SUR): Serum potassium
Study 14561539 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14561539 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11961238 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25755079 — Predictive Biomarker (PRD): Metallothionein-1A
Genes: MT1A; MT1S
Study 25755079 — Predictive Biomarker (PRD): SLC39A1 mRNA
Genes: SLC39A1; IRT1; ZIP1; ZIRTL; CGI-08; CGI-71
Study 19924786 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 10522995 — Predictive Biomarker (PRD): MENT mRNA
Genes: MENT; C1orf56; UNQ547/PRO1104
Study 19864219 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17533210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17533210 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25346373 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 20664274 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20664274 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20664274 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 11910665 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11910665 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30550174 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 22294737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 18802718 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 8775573 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25005331 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18631246 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 7554308 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 1974505 — Surrogate Endpoint (SUR): Blood pressure
Study 21048041 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 21048041 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9124202 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8268729 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22464164 — Surrogate Endpoint (SUR): Blood pressure
Study 9733272 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9194649 — Predictive Biomarker (PRD): MENT mRNA
Genes: MENT; C1orf56; UNQ547/PRO1104
Study 9194649 — Surrogate Endpoint (SUR): Serum testosterone
Study 30732920 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24522623 — Surrogate Endpoint (SUR): Blood pressure
Study 19008149 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10423659 — Surrogate Endpoint (SUR): Blood pressure
Study 8888660 — Surrogate Endpoint (SUR): Blood pressure
Study 8888660 — Surrogate Endpoint (SUR): Serum potassium
Study 1848131 — Surrogate Endpoint (SUR): Blood pressure
Study 1848131 — Surrogate Endpoint (SUR): Serum uric acid
Study 1848131 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6844367 — Surrogate Endpoint (SUR): Blood pressure
Study 20020622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9062865 — Surrogate Endpoint (SUR): Blood pressure
Study 3720569 — Surrogate Endpoint (SUR): Blood pressure
Study 30340813 — Safety Biomarker (SAF): Interleukin 1
Study 18339798 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 1839759 — Surrogate Endpoint (SUR): Serum creatinine
Study 26575696 — Predictive Biomarker (PRD): SLIT1 mRNA
Genes: SLIT1; KIAA0813; MEGF4; SLIL1
Study 26575696 — Predictive Biomarker (PRD): SLIT2 mRNA
Genes: SLIT2; SLIL3
Study 26575696 — Predictive Biomarker (PRD): SLIT3 mRNA
Genes: SLIT3; KIAA0814; MEGF5; SLIL2; UNQ691/PRO1336
Study 20963638 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 20963638 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17351950 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16278618 — Surrogate Endpoint (SUR): Bone mineral density
Study 7318359 — Surrogate Endpoint (SUR): Blood pressure
Study 26949703 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 26949703 — Surrogate Endpoint (SUR): Serum creatinine
Study 8684799 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 27787873 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 25421427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11003358 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26059337 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19663668 — Predictive Biomarker (PRD): FCER2 mRNA
Genes: FCER2; CD23A; CLEC4J; FCE2; IGEBF
Study 19663668 — Predictive Biomarker (PRD): CRHR1 mRNA
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 31064014 — Predictive Biomarker (PRD): NME1 mRNA
Genes: NME1; NDPKA; NM23
Study 21492926 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10795728 — Surrogate Endpoint (SUR): Blood pressure
Study 2061566 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 3842545 — Surrogate Endpoint (SUR): Blood pressure
Study 24607708 — Surrogate Endpoint (SUR): Blood pressure
Study 22437792 — Surrogate Endpoint (SUR): Bone mineral density
Study 18333888 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30219772 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 30219772 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 22377796 — Surrogate Endpoint (SUR): Blood pressure
Study 18355324 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15821191 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10802002 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1800760 — Surrogate Endpoint (SUR): Blood pressure
Study 27167369 — Predictive Biomarker (PRD): DDN mRNA
Genes: DDN; KIAA0749
Study 318952 — Surrogate Endpoint (SUR): Blood pressure
Study 31177924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18511165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18511165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26212719 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 26212719 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15838366 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31454159 — Surrogate Endpoint (SUR): Probing pocket depth
Study 28804048 — Surrogate Endpoint (SUR): Blood pressure
Study 6312008 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31856714 — Predictive Biomarker (PRD): CORIN mRNA
Genes: CORIN; CRN; TMPRSS10
Study 357764 — Surrogate Endpoint (SUR): Blood pressure
Study 30327302 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 22679249 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22679249 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16600928 — Surrogate Endpoint (SUR): Blood pressure
Study 1397716 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 29692005 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 24582046 — Surrogate Endpoint (SUR): Blood pressure
Study 18779444 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24213216 — Surrogate Endpoint (SUR): Bone mineral density
Study 20554120 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31371810 — Surrogate Endpoint (SUR): Blood pressure
Study 31371810 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29431535 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17511759 — Surrogate Endpoint (SUR): Bone mineral density
Study 10070908 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10070908 — Surrogate Endpoint (SUR): Blood pressure
Study 28851320 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21466991 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15030537 — Surrogate Endpoint (SUR): Blood pressure
Study 11486253 — Surrogate Endpoint (SUR): Blood pressure
Study 11486253 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1992551 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30677175 — Surrogate Endpoint (SUR): Blood pressure
Study 26315303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24393852 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2147637 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2147637 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21378348 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 17389005 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17389005 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12915681 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8735854 — Surrogate Endpoint (SUR): Bone mineral density
Study 1720846 — Surrogate Endpoint (SUR): Blood pressure
Study 6816333 — Surrogate Endpoint (SUR): Blood pressure
Study 7970999 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26947059 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 21510830 — Surrogate Endpoint (SUR): Blood pressure
Study 11481401 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 25166623 — Predictive Biomarker (PRD): RGR mRNA
Genes: RGR
Study 16054887 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7609574 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27991432 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16153271 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16153271 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12514672 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31599775 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23062767 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 23062767 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 23062767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12415583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9836028 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9836028 — Surrogate Endpoint (SUR): Blood pressure
Study 31012238 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 27874292 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15115421 — Surrogate Endpoint (SUR): Blood pressure
Study 22938651 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 20531094 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16051518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16051518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8848409 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 8848409 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8848409 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2425204 — Surrogate Endpoint (SUR): Blood pressure
Study 2425204 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28881341 — Surrogate Endpoint (SUR): Total kidney volume
Study 18513512 — Surrogate Endpoint (SUR): Serum creatinine
Study 11982444 — Surrogate Endpoint (SUR): Blood pressure
Study 25131978 — Surrogate Endpoint (SUR): Blood pressure
Study 16020923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6928183 — Surrogate Endpoint (SUR): Blood pressure
Study 22670856 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 18818309 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 12355995 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12355995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10648305 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 8551788 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8551788 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31560580 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 31560580 — Predictive Biomarker (PRD): Hormone receptor
Study 29123208 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 29123208 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8389559 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8389559 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 24556095 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 12106837 — Safety Biomarker (SAF): Reactive oxygen species
Study 28803710 — Predictive Biomarker (PRD): NPC1 mRNA
Genes: NPC1
Study 24191673 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28179226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22980098 — Surrogate Endpoint (SUR): Blood pressure
Study 7988343 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30227980 — Surrogate Endpoint (SUR): Blood pressure
Study 25169589 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19894365 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17076319 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 14658015 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14658015 — Surrogate Endpoint (SUR): Blood pressure
Study 27379922 — Surrogate Endpoint (SUR): Serum creatinine
Study 30196790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27863211 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 22104026 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 22104026 — Surrogate Endpoint (SUR): Bone mineral density
Study 16687913 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16687913 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 29552783 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 20332274 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 20332274 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 29685591 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29685591 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 29685591 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29685591 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20031796 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20031796 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11300367 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8972016 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 24311723 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11