TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31610021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25885668 — Predictive Biomarker (PRD): SRCIN1 mRNA
Genes: SRCIN1; KIAA1684; P140; SNIP
Study 30624952 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 30624952 — Predictive Biomarker (PRD): DOCK3 mRNA
Genes: DOCK3; KIAA0299; MOCA
Study 11504276 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 9737352 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 9737352 — Surrogate Endpoint (SUR): Bone mineral density
Study 9495218 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31842969 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 23871490 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7990079 — Surrogate Endpoint (SUR): Blood pressure
Study 30213849 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 8465360 — Surrogate Endpoint (SUR): Blood pressure
Study 20565454 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 2564834 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2564834 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16778712 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 9264477 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3040923 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 26525188 — Surrogate Endpoint (SUR): Blood pressure
Study 17591031 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22159017 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 1455910 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 25039544 — Surrogate Endpoint (SUR): Serum creatinine
Study 21238825 — Surrogate Endpoint (SUR): Blood pressure
Study 26366481 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 26366481 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26366481 — Surrogate Endpoint (SUR): Serum creatinine
Study 26366481 — Surrogate Endpoint (SUR): Blood pressure
Study 26366481 — Surrogate Endpoint (SUR): Serum uric acid
Study 26366481 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17175305 — Surrogate Endpoint (SUR): Serum creatinine
Study 22571978 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 16268751 — Surrogate Endpoint (SUR): Blood pressure
Study 6781157 — Surrogate Endpoint (SUR): Blood pressure
Study 26955895 — Surrogate Endpoint (SUR): Blood pressure
Study 26955895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30716200 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22453547 — Surrogate Endpoint (SUR): Blood pressure
Study 1526735 — Surrogate Endpoint (SUR): Blood pressure
Study 30108104 — Predictive Biomarker (PRD): miR-31
Genes: MIR31
Study 28836054 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 11672449 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29804377 — Monitoring Biomarker (MOI): HBV DNA
Study 29804377 — Surrogate Endpoint (SUR): Serum creatinine
Study 23715641 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 17399814 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24429320 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 23568851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18492315 — Surrogate Endpoint (SUR): Serum creatinine
Study 14650580 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23688265 — Predictive Biomarker (PRD): Liver iron
Study 10765004 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 27657477 — Surrogate Endpoint (SUR): Serum creatinine
Study 16603634 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 10423634 — Surrogate Endpoint (SUR): Blood pressure
Study 21055143 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21055143 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 21055143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1595849 — Surrogate Endpoint (SUR): Blood pressure
Study 1457432 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24623718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24623718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24623718 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 8611450 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 2285631 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26303352 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26303352 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 19927630 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 15167457 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15167457 — Surrogate Endpoint (SUR): Blood pressure
Study 31397488 — Monitoring Biomarker (MOI): HBV DNA
Study 26216500 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11032589 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22464408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22464408 — Surrogate Endpoint (SUR): Bone mineral density
Study 8017639 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8017639 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25932549 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9447850 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9447850 — Surrogate Endpoint (SUR): Blood pressure
Study 7545256 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 7545256 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25408222 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 20628825 — Surrogate Endpoint (SUR): Blood pressure
Study 15644588 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 15644588 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15644588 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29066219 — Surrogate Endpoint (SUR): Serum potassium
Study 22968743 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 22968743 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18250616 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18250616 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16358997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16358997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30203750 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25246338 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 25246338 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 25246338 — Surrogate Endpoint (SUR): Serum creatinine
Study 20102716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17907108 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17907108 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17907108 — Surrogate Endpoint (SUR): Serum creatinine
Study 10194424 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 17531001 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17531001 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2838288 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 31705746 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31705746 — Surrogate Endpoint (SUR): Serum creatinine
Study 28470591 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 21653691 — Predictive Biomarker (PRD): ACTB mRNA
Genes: ACTB
Study 21653691 — Monitoring Biomarker (MOI): Cell-free DNA
Study 12853380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12853380 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12853380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27121185 — Surrogate Endpoint (SUR): Blood pressure
Study 22513879 — Safety Biomarker (SAF): Hyaluronic acid
Study 2678834 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 8971298 — Surrogate Endpoint (SUR): Blood pressure
Study 31653510 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 31653510 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 11834876 — Surrogate Endpoint (SUR): Blood pressure
Study 18323719 — Surrogate Endpoint (SUR): Blood pressure
Study 15569875 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 9388801 — Surrogate Endpoint (SUR): Blood pressure
Study 7695927 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12217282 — Surrogate Endpoint (SUR): Blood pressure
Study 2652029 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 21584942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29222227 — Surrogate Endpoint (SUR): Blood pressure
Study 12475833 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7921214 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 30625189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26298226 — Surrogate Endpoint (SUR): Blood pressure
Study 26298226 — Surrogate Endpoint (SUR): Serum creatinine
Study 7899583 — Surrogate Endpoint (SUR): Serum calcium
Study 11762413 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 11762413 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 11762413 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 11762413 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7892952 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 7892952 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 3364800 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3364800 — Surrogate Endpoint (SUR): Blood pressure
Study 3364800 — Surrogate Endpoint (SUR): Serum potassium
Study 23023841 — Surrogate Endpoint (SUR): Blood pressure
Study 23023841 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8597678 — Surrogate Endpoint (SUR): Blood pressure
Study 8597678 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8597678 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9594050 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28582812 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28582812 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11447364 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11447364 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25048955 — Surrogate Endpoint (SUR): Blood pressure
Study 23013352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19945816 — Surrogate Endpoint (SUR): Blood pressure
Study 10430713 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7556961 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1934686 — Safety Biomarker (SAF): Hyaluronic acid
Study 14981335 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 14981335 — Surrogate Endpoint (SUR): Blood pressure
Study 444345 — Surrogate Endpoint (SUR): Serum potassium
Study 29547835 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26803690 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 26803690 — Surrogate Endpoint (SUR): Blood pressure
Study 7297145 — Surrogate Endpoint (SUR): Blood pressure
Study 20864946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23403945 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23403945 — Safety Biomarker (SAF): Reactive oxygen species
Study 23403945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17124283 — Surrogate Endpoint (SUR): Bone mineral density
Study 29151034 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9097890 — Surrogate Endpoint (SUR): Blood pressure
Study 29044496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11199194 — Surrogate Endpoint (SUR): Bone mineral density
Study 1629748 — Surrogate Endpoint (SUR): Serum creatinine
Study 27941065 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 27941065 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25943660 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 16115972 — Surrogate Endpoint (SUR): Blood pressure
Study 30892782 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 15860521 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10461471 — Safety Biomarker (SAF): Hyaluronic acid
Study 7828381 — Surrogate Endpoint (SUR): Blood pressure
Study 21463065 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8559491 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31112379 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21943940 — Surrogate Endpoint (SUR): Serum creatinine
Study 27447966 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17951945 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17951945 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16208150 — Surrogate Endpoint (SUR): Blood pressure
Study 2273081 — Surrogate Endpoint (SUR): Blood pressure
Study 27719707 — Predictive Biomarker (PRD): SFRP1 mRNA
Genes: SFRP1; FRP; FRP1; SARP2
Study 22894553 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12517686 — Surrogate Endpoint (SUR): Blood pressure
Study 10648307 — Surrogate Endpoint (SUR): Blood pressure
Study 25199121 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 19935757 — Surrogate Endpoint (SUR): Bacterial count
Study 19935757 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 809253 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30961412 — Surrogate Endpoint (SUR): Blood pressure
Study 25307195 — Surrogate Endpoint (SUR): Blood pressure
Study 15154946 — Surrogate Endpoint (SUR): Blood pressure
Study 8446039 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8446039 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3716914 — Surrogate Endpoint (SUR): Blood pressure
Study 22555227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22555227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18605811 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30966821 — Surrogate Endpoint (SUR): Blood pressure
Study 12036483 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7579054 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 25297344 — Surrogate Endpoint (SUR): Blood pressure
Study 8888359 — Surrogate Endpoint (SUR): Blood pressure
Study 26267328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21962066 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 18469235 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2895705 — Surrogate Endpoint (SUR): Blood pressure
Study 28623414 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study 25899452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20038723 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20038723 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 17869973 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10065682 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10065682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8828358 — Surrogate Endpoint (SUR): Serum creatinine
Study 2866097 — Predictive Biomarker (PRD): NAPA mRNA
Genes: NAPA; SNAPA
Study 29327047 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29327047 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 29327047 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study 25285367 — Surrogate Endpoint (SUR): Blood pressure
Study 22689317 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 22689317 — Predictive Biomarker (PRD): ATP-binding cassette sub-family C member 11
Genes: ABCC11; MRP8
Study 22689317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16283275 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30278429 — Surrogate Endpoint (SUR): Blood pressure
Study 30278429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30278429 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30278429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11966868 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 11966868 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 7772357 — Surrogate Endpoint (SUR): Blood pressure
Study 24146762 — Surrogate Endpoint (SUR): Blood pressure
Study 18400322 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 6469823 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30032504 — Surrogate Endpoint (SUR): Blood pressure
Study 12030736 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9972670 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31068018 — Surrogate Endpoint (SUR): Blood pressure
Study 28974570 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28974570 — Surrogate Endpoint (SUR): Blood pressure
Study 21193696 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 12559215 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12559215 — Surrogate Endpoint (SUR): Blood pressure
Study 8446138 — Surrogate Endpoint (SUR): Blood pressure
Study 29898035 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 18633420 — Surrogate Endpoint (SUR): Bone mineral density
Study 16849118 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12770975 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 12770975 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9601864 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8224265 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 3896278 — Surrogate Endpoint (SUR): Blood pressure
Study 26642810 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26642810 — Predictive Biomarker (PRD): Hormone receptor
Study 24690511 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 18591457 — Surrogate Endpoint (SUR): Blood pressure
Study 17021318 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14618246 — Surrogate Endpoint (SUR): Serum sodium
Study 30304108 — Surrogate Endpoint (SUR): Bone mineral density
Study 16168278 — Surrogate Endpoint (SUR): Blood pressure
Study 12514662 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10536645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2054272 — Surrogate Endpoint (SUR): Blood pressure
Study 30716803 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 11590993 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 25792076 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study 18070967 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 8900980 — Surrogate Endpoint (SUR): Blood pressure
Study 11023140 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27385662 — Surrogate Endpoint (SUR): Blood pressure
Study 14602790 — Surrogate Endpoint (SUR): Blood pressure
Study 12454840 — Monitoring Biomarker (MOI): HBV DNA
Study 24797321 — Predictive Biomarker (PRD): ADH1B mRNA
Genes: ADH1B; ADH2
Study 24797321 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 31321514 — Predictive Biomarker (PRD): METTL1 mRNA
Genes: METTL1; C12orf1
Study 31321514 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 31321514 — Predictive Biomarker (PRD): MICB mRNA
Genes: MICB; PERB11.2
Study 31321514 — Predictive Biomarker (PRD): GZMA mRNA
Genes: GZMA; CTLA3; HFSP
Study 28647451 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 21528593 — Surrogate Endpoint (SUR): Blood pressure
Study 19447837 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 14722028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14722028 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27354202 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 24370801 — Predictive Biomarker (PRD): MB mRNA
Genes: MB