TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11299268 — Predictive Biomarker (PRD): S100A1 mRNA
Genes: S100A1; S100A
Study 11299268 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30031572 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 23582628 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16616233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16616233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16616233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1611965 — Surrogate Endpoint (SUR): Blood pressure
Study 30661082 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 30661082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22357106 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17854748 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 11978899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9856380 — Surrogate Endpoint (SUR): Blood pressure
Study 15580192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3333523 — Surrogate Endpoint (SUR): Blood pressure
Study 29724529 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20978709 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 10704616 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25677309 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 10099043 — Surrogate Endpoint (SUR): Bone mineral density
Study 7656846 — Surrogate Endpoint (SUR): Blood pressure
Study 30935251 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 21840466 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26317357 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 14764813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14764813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9137023 — Surrogate Endpoint (SUR): Blood pressure
Study 21878166 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10453590 — Predictive Biomarker (PRD): TSN mRNA
Genes: TSN
Study 7881702 — Surrogate Endpoint (SUR): Blood pressure
Study 31926142 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31926142 — Surrogate Endpoint (SUR): Blood pressure
Study 21673483 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 21673483 — Surrogate Endpoint (SUR): Blood pressure
Study 19892673 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 14633141 — Surrogate Endpoint (SUR): Serum creatinine
Study 1493134 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22796139 — Predictive Biomarker (PRD): TLR5 mRNA
Genes: TLR5; TIL3
Study 22796139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12364991 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10916802 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7954027 — Surrogate Endpoint (SUR): Blood pressure
Study 16740865 — Surrogate Endpoint (SUR): Blood pressure
Study 26995280 — Surrogate Endpoint (SUR): Blood pressure
Study 12599080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12599080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12599080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12599080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6141424 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27743432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27743432 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15821887 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15821887 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 15821887 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 12064344 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10223782 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10223782 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2037702 — Surrogate Endpoint (SUR): Blood pressure
Study 26467311 — Surrogate Endpoint (SUR): Blood pressure
Study 17620070 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 17620070 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 16046582 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16046582 — Surrogate Endpoint (SUR): Serum testosterone
Study 21833777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11834236 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 25569817 — Surrogate Endpoint (SUR): Bone mineral density
Study 25569817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22909294 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30608521 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30608521 — Surrogate Endpoint (SUR): Blood pressure
Study 15013038 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 30568305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26387494 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 26387494 — Monitoring Biomarker (MOI): HBV DNA
Study 26527790 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21429905 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 11747004 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8098222 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2436002 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1315483 — Surrogate Endpoint (SUR): Blood pressure
Study 29978372 — Predictive Biomarker (PRD): TTL mRNA
Genes: TTL
Study 24500154 — Safety Biomarker (SAF): Reactive oxygen species
Study 19079956 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 16510769 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8858409 — Predictive Biomarker (PRD): OSTM1 mRNA
Genes: OSTM1; GL; HSPC019; UNQ6098/PRO21201
Study 25007003 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 25014688 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16001113 — Surrogate Endpoint (SUR): Blood pressure
Study 10357743 — Surrogate Endpoint (SUR): Serum creatinine
Study 10357743 — Surrogate Endpoint (SUR): Serum calcium
Study 2166429 — Surrogate Endpoint (SUR): Serum testosterone
Study 31210099 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 11583199 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25976288 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 23408034 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23408034 — Surrogate Endpoint (SUR): Blood pressure
Study 14745865 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 8156739 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8156739 — Surrogate Endpoint (SUR): Serum sodium
Study 18063230 — Surrogate Endpoint (SUR): Bone mineral density
Study 17163286 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17163286 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17163286 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17163286 — Surrogate Endpoint (SUR): Blood pressure
Study 23710550 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23710550 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15621558 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15621558 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10320861 — Surrogate Endpoint (SUR): Blood pressure
Study 7917359 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 31588607 — Predictive Biomarker (PRD): CA3 mRNA
Genes: CA3
Study 9457396 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26579985 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18835411 — Surrogate Endpoint (SUR): Blood pressure
Study 15479936 — Surrogate Endpoint (SUR): Blood pressure
Study 25257064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20378736 — Surrogate Endpoint (SUR): Blood pressure
Study 26434372 — Surrogate Endpoint (SUR): Blood pressure
Study 26434372 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19842576 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30210590 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30210590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 30210590 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30210590 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 26810526 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18997461 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 16014054 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16014054 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10551966 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1341478 — Monitoring Biomarker (MOI): HBV DNA
Study 30983166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30983166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18827631 — Predictive Biomarker (PRD): TICAM2 mRNA
Genes: TICAM2; TIRAP3; TIRP; TRAM
Study 10919936 — Surrogate Endpoint (SUR): Blood pressure
Study 8670579 — Surrogate Endpoint (SUR): Bone mineral density
Study 8670579 — Surrogate Endpoint (SUR): Serum testosterone
Study 30753272 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 21543209 — Surrogate Endpoint (SUR): Blood pressure
Study 17255882 — Surrogate Endpoint (SUR): Blood pressure
Study 12141616 — Surrogate Endpoint (SUR): Blood pressure
Study 8697161 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31653221 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 31653221 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25712255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25712255 — Surrogate Endpoint (SUR): Bone mineral density
Study 16633920 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 16633920 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16633920 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10840005 — Surrogate Endpoint (SUR): Blood pressure
Study 31926554 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21629990 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21629990 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19009508 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study 19009508 — Surrogate Endpoint (SUR): Serum creatinine
Study 8199723 — Surrogate Endpoint (SUR): Blood pressure
Study 27155612 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19577992 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 7633178 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25773936 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21079055 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 14555500 — Predictive Biomarker (PRD): Hormone receptor
Study 28433753 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7015139 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26822091 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 26822091 — Predictive Biomarker (PRD): TBC1D1 mRNA
Genes: TBC1D1; KIAA1108
Study 26822091 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 12090782 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31852482 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 31852482 — Predictive Biomarker (PRD): CD244 mRNA
Genes: CD244; 2B4
Study 31852482 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 22965588 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 22965588 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22965588 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9781932 — Surrogate Endpoint (SUR): Blood pressure
Study 9781932 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3045553 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29759857 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29759857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16479736 — Predictive Biomarker (PRD): SARM1 mRNA
Genes: SARM1; KIAA0524; SAMD2; SARM
Study 30062633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24566584 — Surrogate Endpoint (SUR): Bone mineral density
Study 19935106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29202611 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 24614619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24614619 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24614619 — Safety Biomarker (SAF): IL-6 and IL-10
Study 28205322 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28205322 — Surrogate Endpoint (SUR): Blood pressure
Study 26297649 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 10929023 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 10929023 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 31089818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29737804 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29737804 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31823937 — Surrogate Endpoint (SUR): Blood pressure
Study 19091990 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 10683506 — Surrogate Endpoint (SUR): Blood pressure
Study 7681656 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30922990 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25444805 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 21980993 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 17112849 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19720922 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 19720922 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19720922 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17728532 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15504287 — Monitoring Biomarker (MOI): HBV DNA
Study 23252004 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6405876 — Surrogate Endpoint (SUR): Blood pressure
Study 25227538 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 23019949 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 16941337 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19940233 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12576938 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12576938 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26751602 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23524015 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20975611 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20975611 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20975611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20975611 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20975611 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17159081 — Surrogate Endpoint (SUR): Blood pressure
Study 17159081 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25175385 — Surrogate Endpoint (SUR): Blood pressure
Study 23644819 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 23644819 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23644819 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study 15002318 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 7573564 — Surrogate Endpoint (SUR): Blood pressure
Study 26040200 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15942765 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 15942765 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 11006058 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22227725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20195825 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20195825 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 18547179 — Safety Biomarker (SAF): Hyaluronic acid
Study 11788628 — Surrogate Endpoint (SUR): Bone mineral density
Study 28880867 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study 28880867 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 28880867 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28880867 — Safety Biomarker (SAF): CDA
Genes: CDD
Study 28880867 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24239210 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24239210 — Surrogate Endpoint (SUR): Pathological complete response
Study 24239210 — Predictive Biomarker (PRD): Hormone receptor
Study 18475165 — Surrogate Endpoint (SUR): Serum calcium
Study 26884660 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23406536 — Predictive Biomarker (PRD): DYSF mRNA
Genes: DYSF; FER1L1
Study 21931864 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 21931864 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 11232022 — Surrogate Endpoint (SUR): Blood pressure
Study 1425532 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 26498173 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 24803153 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24803153 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17400393 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 16312917 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 16312917 — Surrogate Endpoint (SUR): Blood pressure
Study 26842867 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26842867 — Surrogate Endpoint (SUR): Blood pressure
Study 17321484 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17321484 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 17321484 — Surrogate Endpoint (SUR): Blood pressure
Study 25320361 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 18283233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19422479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11022179 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18206732 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 14688811 — Surrogate Endpoint (SUR): Blood pressure
Study 31882240 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 29055624 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 25149995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25149995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25149995 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22143739 — Surrogate Endpoint (SUR): Blood pressure
Study 18279948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15860753 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4