TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24581894 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9603592 — Surrogate Endpoint (SUR): Blood pressure
Study 26661992 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22791756 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 18195264 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25802954 — Surrogate Endpoint (SUR): Blood pressure
Study 23339811 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9424900 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 14610160 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1794215 — Surrogate Endpoint (SUR): Blood pressure
Study 1794215 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22727431 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20634298 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 7772352 — Surrogate Endpoint (SUR): Blood pressure
Study 28961838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10455343 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10455343 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28412747 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 28412747 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 9599737 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2732164 — Surrogate Endpoint (SUR): Blood pressure
Study 28903775 — Surrogate Endpoint (SUR): Blood pressure
Study 26002049 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26002049 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26002049 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21373802 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 21373802 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 21373802 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 3316303 — Surrogate Endpoint (SUR): Blood pressure
Study 3316303 — Surrogate Endpoint (SUR): Serum potassium
Study 3316303 — Surrogate Endpoint (SUR): Serum uric acid
Study 18588355 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18588355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18588355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16630994 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16630994 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16630994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10881952 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1294606 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30168266 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 26907090 — Predictive Biomarker (PRD): FUT2 mRNA
Genes: FUT2; SEC2
Study 24151017 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3392233 — Surrogate Endpoint (SUR): Blood pressure
Study 31008870 — Surrogate Endpoint (SUR): Blood pressure
Study 29248107 — Predictive Biomarker (PRD): RPSA mRNA
Genes: RPSA; LAMBR; LAMR1
Study 26980809 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 28365440 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 14674148 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31259655 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22939114 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 22939114 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21029339 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29663513 — Predictive Biomarker (PRD): GRK5 mRNA
Genes: GRK5; GPRK5
Study 29663513 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 24951609 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9856371 — Surrogate Endpoint (SUR): Blood pressure
Study 9856371 — Surrogate Endpoint (SUR): Serum calcium
Study 38214 — Surrogate Endpoint (SUR): Blood pressure
Study 31237450 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 31237450 — Surrogate Endpoint (SUR): Serum testosterone
Study 26130237 — Safety Biomarker (SAF): Cytochrome c
Study 17913695 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 11281339 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11281339 — Surrogate Endpoint (SUR): Blood pressure
Study 30929570 — Surrogate Endpoint (SUR): Blood pressure
Study 21515479 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19637348 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 11570021 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24621976 — Surrogate Endpoint (SUR): Blood pressure
Study 24621976 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18340390 — Surrogate Endpoint (SUR): Blood pressure
Study 12665170 — Predictive Biomarker (PRD): HPN mRNA
Genes: HPN; TMPRSS1
Study 31540867 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 25751232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25751232 — Surrogate Endpoint (SUR): Blood pressure
Study 21325108 — Surrogate Endpoint (SUR): Blood pressure
Study 12707979 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 30710837 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 30710837 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 30710837 — Surrogate Endpoint (SUR): Serum calcium
Study 19334042 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8122957 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 8122957 — Surrogate Endpoint (SUR): Blood pressure
Study 2521863 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 9883 — Surrogate Endpoint (SUR): Blood pressure
Study 25652389 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 19222404 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 1466618 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11075309 — Surrogate Endpoint (SUR): Serum calcium
Study 28496022 — Surrogate Endpoint (SUR): Blood pressure
Study 24521993 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21720426 — Surrogate Endpoint (SUR): Blood pressure
Study 11448018 — Surrogate Endpoint (SUR): Bone mineral density
Study 23383690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23383690 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 23383690 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19506112 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19506112 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17709433 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11485526 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11485526 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11485526 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9724277 — Surrogate Endpoint (SUR): Blood pressure
Study 30333054 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 28375706 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28375706 — Predictive Biomarker (PRD): Hormone receptor
Study 8900987 — Surrogate Endpoint (SUR): Blood pressure
Study 31489410 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 25866155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25866155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25866155 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 24525232 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study 24525232 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24525232 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22774398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 24178584 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24178584 — Safety Biomarker (SAF): BDNF
Study 20207825 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21930596 — Surrogate Endpoint (SUR): Blood pressure
Study 21930596 — Safety Biomarker (SAF): Reactive oxygen species
Study 16426275 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 15561035 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3297124 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 3297124 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3297124 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3297124 — Surrogate Endpoint (SUR): Blood pressure
Study 3036724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 14985996 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 10095796 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10095796 — Surrogate Endpoint (SUR): Blood pressure
Study 10095796 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8800885 — Surrogate Endpoint (SUR): Serum sodium
Study 14560186 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 8729308 — Surrogate Endpoint (SUR): Blood pressure
Study 30659292 — Surrogate Endpoint (SUR): Sperm parameters
Study 25131184 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25131184 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 1377741 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 31578954 — Surrogate Endpoint (SUR): Bone mineral density
Study 23698590 — Surrogate Endpoint (SUR): Blood pressure
Study 8985298 — Monitoring Biomarker (MOI): HBV DNA
Study 27526120 — Surrogate Endpoint (SUR): Serum creatinine
Study 23974954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20537746 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8706481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17667569 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 26386799 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17703100 — Predictive Biomarker (PRD): ACP1 mRNA
Genes: ACP1
Study 16794028 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9058224 — Surrogate Endpoint (SUR): Blood pressure
Study 8382840 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8382840 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 14626378 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8636581 — Surrogate Endpoint (SUR): Blood pressure
Study 1336356 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1336356 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 2866786 — Surrogate Endpoint (SUR): Blood pressure
Study 29206782 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27405859 — Surrogate Endpoint (SUR): Blood pressure
Study 14712987 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14712987 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1643806 — Surrogate Endpoint (SUR): Blood pressure
Study 23746558 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16639484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11834533 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 11834533 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7527493 — Surrogate Endpoint (SUR): Serum creatinine
Study 25579006 — Safety Biomarker (SAF): Hyaluronic acid
Study 19164343 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 2108885 — Surrogate Endpoint (SUR): Serum testosterone
Study 518076 — Surrogate Endpoint (SUR): Serum creatinine
Study 19843321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20865841 — Safety Biomarker (SAF): Hyaluronic acid
Study 15671427 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1905960 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29690736 — Surrogate Endpoint (SUR): Blood pressure
Study 26890974 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 26890974 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26890974 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17472600 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 25482871 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 25482871 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 25482871 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 25482871 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 25482871 — Predictive Biomarker (PRD): CCL26 mRNA
Genes: CCL26; SCYA26; UNQ216/PRO242
Study 25482871 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22740508 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 10551383 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28727231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28727231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9412549 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7528360 — Surrogate Endpoint (SUR): Serum creatinine
Study 31253213 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 19737278 — Surrogate Endpoint (SUR): Serum testosterone
Study 28025964 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 24709775 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 24709775 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24709775 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 14602761 — Surrogate Endpoint (SUR): Bone mineral density
Study 14602761 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10744147 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12500073 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 11303310 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29220105 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 29220105 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 29220105 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 29085004 — Safety Biomarker (SAF): Cytochrome c
Study 21338276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30918134 — Predictive Biomarker (PRD): AZGP1 mRNA
Genes: AZGP1; ZAG; ZNGP1
Study 17121211 — Surrogate Endpoint (SUR): Blood pressure
Study 28598590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 25100359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25100359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25100359 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 25100359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17586413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17586413 — Surrogate Endpoint (SUR): Blood pressure
Study 10533793 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 1676238 — Surrogate Endpoint (SUR): Blood pressure
Study 29780293 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29780293 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29780293 — Safety Biomarker (SAF): BDNF
Study 27059880 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 24655586 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 1970108 — Safety Biomarker (SAF): Interleukin 1
Study 7425360 — Surrogate Endpoint (SUR): Blood pressure
Study 22012805 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22012805 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22012805 — Surrogate Endpoint (SUR): Blood pressure
Study 19571161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19571161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19571161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11347834 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11347834 — Safety Biomarker (SAF): MTHFR
Study 8255974 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27486125 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17977950 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 17977950 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 19709417 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 2972158 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2972158 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 19303793 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15252908 — Surrogate Endpoint (SUR): Blood pressure
Study 15252908 — Surrogate Endpoint (SUR): Serum creatinine
Study 26208341 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 26208341 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26208341 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19952817 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12968982 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 9200808 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9200808 — Surrogate Endpoint (SUR): Blood pressure
Study 8258267 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16024973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3913379 — Surrogate Endpoint (SUR): Blood pressure
Study 29901507 — Surrogate Endpoint (SUR): Bone mineral density
Study 2960296 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27352414 — Surrogate Endpoint (SUR): Serum uric acid
Study 24708338 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 21569996 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17049693 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12771518 — Predictive Biomarker (PRD): Hormone receptor
Study 22748591 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22748591 — Surrogate Endpoint (SUR): Serum creatinine
Study 16683408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10988282 — Surrogate Endpoint (SUR): Blood pressure
Study 21850574 — Surrogate Endpoint (SUR): Blood pressure
Study 12857474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12857474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6748924 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30650322 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 30304106 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 30304106 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30304106 — Surrogate Endpoint (SUR): Blood pressure
Study 26935578 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 17409312 — Surrogate Endpoint (SUR): Serum creatinine
Study 15365746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15365746 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 15365746 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 9756423 — Surrogate Endpoint (SUR): Blood pressure
Study 29649631 — Surrogate Endpoint (SUR): Blood pressure
Study 16503543 — Surrogate Endpoint (SUR): Blood pressure
Study 10638374 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30288918 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25880054 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 19850207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19850207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28424185 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 28424185 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28424185 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7614505 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 983179 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 29311704 — Surrogate Endpoint (SUR): Blood pressure
Study 23418955 — Surrogate Endpoint (SUR): Blood pressure
Study 19967620 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 15181054 — Surrogate Endpoint (SUR): Blood pressure