TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18272264 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 18272264 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10701819 — Surrogate Endpoint (SUR): Blood pressure
Study 7903212 — Surrogate Endpoint (SUR): Blood pressure
Study 3119650 — Surrogate Endpoint (SUR): Serum testosterone
Study 11794698 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11794698 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24401214 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24401214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21177169 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16907846 — Monitoring Biomarker (MOI): HBV DNA
Study 23497020 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 23497020 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 21476202 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 17875549 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 9824785 — Surrogate Endpoint (SUR): Serum potassium
Study 2757244 — Surrogate Endpoint (SUR): Blood pressure
Study 25632066 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25632066 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19661125 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14764773 — Surrogate Endpoint (SUR): Bone mineral density
Study 8360063 — Surrogate Endpoint (SUR): Blood pressure
Study 31547713 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27647770 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20212250 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7790785 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 29040268 — Surrogate Endpoint (SUR): Blood pressure
Study 21440734 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 21440734 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1992688 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27513191 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 15302288 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9543145 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29772855 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 26595359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26595359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21910803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21910803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10415058 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 24137971 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17426207 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17426207 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 17426207 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 17426207 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2899509 — Surrogate Endpoint (SUR): Blood pressure
Study 2899509 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31931098 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31931098 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30695908 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 28315160 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28315160 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28315160 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 28315160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28315160 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26289437 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19690450 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 12819161 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 23116485 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18847427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26567275 — Safety Biomarker (SAF): Interleukin 12
Study 26567275 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26567275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19732200 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 3072179 — Surrogate Endpoint (SUR): Blood pressure
Study 24029743 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 18664346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18664346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18664346 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18664346 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31947628 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 18295798 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16466166 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16466166 — Safety Biomarker (SAF): Hyaluronic acid
Study 16466166 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16083524 — Surrogate Endpoint (SUR): Serum creatinine
Study 9744431 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7801609 — Monitoring Biomarker (MOI): HBV DNA
Study 21216868 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 21216868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15508053 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 25503414 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23456769 — Safety Biomarker (SAF): MTHFR
Study 20705350 — Surrogate Endpoint (SUR): Blood pressure
Study 20705350 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15585774 — Surrogate Endpoint (SUR): Serum calcium
Study 6426830 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 23675990 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20442989 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16021194 — Surrogate Endpoint (SUR): Blood pressure
Study 8672323 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 31033154 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 24004517 — Surrogate Endpoint (SUR): Blood pressure
Study 29261442 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27585671 — Surrogate Endpoint (SUR): Bone mineral density
Study 18716362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18716362 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18716362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18716362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15729174 — Surrogate Endpoint (SUR): Serum creatinine
Study 12775230 — Pharmacodynamic Biomarker (PDY): Bcl-2 to Bax
Study 23180751 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23180751 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23180751 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 23180751 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 15505150 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9684799 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 21128827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21128827 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24997005 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9535150 — Surrogate Endpoint (SUR): Blood pressure
Study 2173168 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 22151296 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17374034 — Predictive Biomarker (PRD): OPRK1 mRNA
Genes: OPRK1; OPRK
Study 17374034 — Predictive Biomarker (PRD): OPRD1 mRNA
Genes: OPRD1; OPRD
Study 22419369 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 22419369 — Surrogate Endpoint (SUR): Bone mineral density
Study 28623944 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16940406 — Surrogate Endpoint (SUR): Blood pressure
Study 16940406 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12930031 — Surrogate Endpoint (SUR): Blood pressure
Study 16641119 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16641119 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16369129 — Safety Biomarker (SAF): Interleukin 1
Study 16369129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7920884 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 29538636 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29876530 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27178989 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 20012601 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17413685 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21543375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21543375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10818057 — Surrogate Endpoint (SUR): Serum potassium
Study 2439827 — Surrogate Endpoint (SUR): Blood pressure
Study 28964662 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 23195006 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 9168506 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26821621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24582900 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 16402634 — Surrogate Endpoint (SUR): Bone mineral density
Study 16402634 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16402634 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30727980 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 26475420 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 1108582 — Surrogate Endpoint (SUR): Blood pressure
Study 11783328 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25431431 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 15040538 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15040538 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 3630804 — Surrogate Endpoint (SUR): Blood pressure
Study 31285069 — Surrogate Endpoint (SUR): Bone mineral density
Study 15041578 — Surrogate Endpoint (SUR): Blood pressure
Study 8061854 — Surrogate Endpoint (SUR): Blood pressure
Study 29961572 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 29961572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29961572 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11677359 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 11677359 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11677359 — Surrogate Endpoint (SUR): Blood pressure
Study 29221717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29221717 — Surrogate Endpoint (SUR): Blood pressure
Study 24618153 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 24618153 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24618153 — Surrogate Endpoint (SUR): Pathological complete response
Study 1482267 — Surrogate Endpoint (SUR): Blood pressure
Study 15795365 — Surrogate Endpoint (SUR): Blood pressure
Study 12486649 — Surrogate Endpoint (SUR): Blood pressure
Study 2350052 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9506008 — Surrogate Endpoint (SUR): Serum testosterone
Study 23939953 — Monitoring Biomarker (MOI): HBV DNA
Study 26717219 — Surrogate Endpoint (SUR): Blood pressure
Study 21654521 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15811062 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12459402 — Surrogate Endpoint (SUR): Serum creatinine
Study 21793388 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19010579 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 19010579 — Surrogate Endpoint (SUR): Blood pressure
Study 9833910 — Surrogate Endpoint (SUR): Bone mineral density
Study 799564 — Surrogate Endpoint (SUR): Blood pressure
Study 30967530 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30967530 — Safety Biomarker (SAF): BDNF
Study 28287798 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 25953971 — Surrogate Endpoint (SUR): Blood pressure
Study 17923131 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 16197663 — Surrogate Endpoint (SUR): Bone mineral density
Study 24626998 — Surrogate Endpoint (SUR): Serum creatinine
Study 22320241 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 15729065 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 2668464 — Surrogate Endpoint (SUR): Blood pressure
Study 30480353 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30480353 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30480353 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27987228 — Predictive Biomarker (PRD): NE
Study 25204316 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 25204316 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25204316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25204316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25953327 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19829124 — Surrogate Endpoint (SUR): Serum creatinine
Study 30112581 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19178509 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31513531 — Surrogate Endpoint (SUR): Blood pressure
Study 15305234 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 15305234 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 15448423 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 20470379 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 18383390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16100773 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16100773 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12426515 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2236455 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 26376822 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18029489 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16148184 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 10376852 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10376852 — Surrogate Endpoint (SUR): Blood pressure
Study 1984505 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21149919 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10200809 — Surrogate Endpoint (SUR): Blood pressure
Study 8706198 — Surrogate Endpoint (SUR): Blood pressure
Study 2357134 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 24372992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19605528 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 7599569 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7599569 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28101704 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 21559987 — Safety Biomarker (SAF): Hyaluronic acid
Study 11699052 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2467136 — Surrogate Endpoint (SUR): Blood pressure
Study 27979834 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 9579235 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 29927785 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 29927785 — Surrogate Endpoint (SUR): Bone mineral density
Study 27239927 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17709365 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12006508 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2765377 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 18316547 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22236488 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 20132138 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10567754 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 10567754 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 25490913 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23890351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23890351 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23890351 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23890351 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 14990595 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 11374092 — Predictive Biomarker (PRD): EEF1A2 mRNA
Genes: EEF1A2; EEF1AL; STN
Study 9404766 — Surrogate Endpoint (SUR): Blood pressure
Study 25618800 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25618800 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16967629 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16967629 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9011450 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9011450 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29321218 — Surrogate Endpoint (SUR): Blood pressure
Study 11899903 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 11899903 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26301771 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 4042527 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20034816 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10103305 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2260333 — Surrogate Endpoint (SUR): Blood pressure
Study 18423807 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 18423807 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16503669 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 10679908 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1606113 — Surrogate Endpoint (SUR): Blood pressure
Study 18826853 — Surrogate Endpoint (SUR): Serum calcium
Study 15796145 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12783045 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10542989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10542989 — Safety Biomarker (SAF): Heat shock 70 kDa
Study 10542989 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19244174 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 8045953 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 23894039 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16825698 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9744143 — Surrogate Endpoint (SUR): Blood pressure
Study 30825342 — Surrogate Endpoint (SUR): Blood pressure
Study 20924595 — Surrogate Endpoint (SUR): Blood pressure
Study 19781408 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19781408 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19781408 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19781408 — Surrogate Endpoint (SUR): Blood pressure
Study 31306056 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28916311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 12859326 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6373331 — Surrogate Endpoint (SUR): Blood pressure