TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30528315 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 30528315 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 30528315 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30528315 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30528315 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28935146 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28935146 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26813555 — Surrogate Endpoint (SUR): Blood pressure
Study 2695280 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2695280 — Safety Biomarker (SAF): 51Cr-EDTA
Study 2695280 — Surrogate Endpoint (SUR): Blood pressure
Study 568870 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30961440 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24386561 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24386561 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24386561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9304176 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9304176 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 19191940 — Surrogate Endpoint (SUR): Blood pressure
Study 15462115 — Surrogate Endpoint (SUR): Serum creatinine
Study 9241099 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8320926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8320926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23197596 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 27663567 — Predictive Biomarker (PRD): Hormone receptor
Study 24611906 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24611906 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24611906 — Surrogate Endpoint (SUR): Blood pressure
Study 22440498 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19325538 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 1233250 — Surrogate Endpoint (SUR): Blood pressure
Study 18290996 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29709099 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 29709099 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 21918206 — Surrogate Endpoint (SUR): Blood pressure
Study 12654603 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 499107 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15115713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12108885 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 9934937 — Surrogate Endpoint (SUR): Blood pressure
Study 7557091 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 730419 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 730419 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 23590237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23590237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23590237 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15606550 — Safety Biomarker (SAF): Human leucocyte antigen
Study 19856443 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 15818652 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 21232139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15577425 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11238476 — Surrogate Endpoint (SUR): Bone mineral density
Study 26711065 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 23176966 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 1598878 — Surrogate Endpoint (SUR): Blood pressure
Study 22314329 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 18059578 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18059578 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31568288 — Safety Biomarker (SAF): Hyaluronic acid
Study 21470389 — Surrogate Endpoint (SUR): Blood pressure
Study 28670407 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 25406682 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22337568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14734464 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 14734464 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 9579445 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25829263 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 15242248 — Predictive Biomarker (PRD): Hormone receptor
Study 28817334 — Surrogate Endpoint (SUR): Blood pressure
Study 20812862 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20812862 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 18608367 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 8463768 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8463768 — Surrogate Endpoint (SUR): Blood pressure
Study 27086023 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 27086023 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 20978028 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24530144 — Surrogate Endpoint (SUR): Blood pressure
Study 11445849 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 11445849 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 11445849 — Predictive Biomarker (PRD): GAPDH mRNA
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 11360524 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 11360524 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 28259304 — Surrogate Endpoint (SUR): Blood pressure
Study 26394270 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 23385649 — Surrogate Endpoint (SUR): Blood pressure
Study 21559038 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17964616 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29890270 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 19889796 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19889796 — Predictive Biomarker (PRD): CCR1 mRNA
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 6583715 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 25374024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25374024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25374024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25374024 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25374024 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18632147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26844861 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26844861 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19474651 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17507543 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15470330 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8489563 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25775494 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 25775494 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study 24624877 — Predictive Biomarker (PRD): ILK mRNA
Genes: ILK; ILK1; ILK2
Study 19463347 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 14674506 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 8434380 — Surrogate Endpoint (SUR): Blood pressure
Study 8434380 — Surrogate Endpoint (SUR): Serum creatinine
Study 12518724 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18990973 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 16487836 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8963977 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7498204 — Surrogate Endpoint (SUR): Blood pressure
Study 7026336 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7026336 — Surrogate Endpoint (SUR): Blood pressure
Study 21458107 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 14732872 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 14732872 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11054648 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11956002 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 7712756 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28088688 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28088688 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31186299 — Surrogate Endpoint (SUR): Serum uric acid
Study 31186299 — Surrogate Endpoint (SUR): Blood pressure
Study 23944300 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 15291378 — Surrogate Endpoint (SUR): Blood pressure
Study 8903980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8903980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26718414 — Surrogate Endpoint (SUR): Blood pressure
Study 26718414 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20100020 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17242499 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12540390 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12540390 — Surrogate Endpoint (SUR): Blood pressure
Study 10837004 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10837004 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 25790807 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25790807 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23995774 — Predictive Biomarker (PRD): OPRK1 mRNA
Genes: OPRK1; OPRK
Study 21185661 — Surrogate Endpoint (SUR): Blood pressure
Study 19272639 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12174784 — Surrogate Endpoint (SUR): Blood pressure
Study 9850348 — Surrogate Endpoint (SUR): Bone mineral density
Study 28008098 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26004151 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17327603 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 24966097 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 22306907 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20410684 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 18545194 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 15503297 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6171898 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27388566 — Predictive Biomarker (PRD): ACP3 mRNA
Genes: ACP3; ACPP
Study 24857044 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 21336431 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 8874658 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 22189827 — Safety Biomarker (SAF): Hyaluronic acid
Study 17582281 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31025924 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 22837306 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study 22837306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23414504 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 9121678 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 2447715 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11590533 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18662191 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study 11796428 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11796428 — Surrogate Endpoint (SUR): Serum calcium
Study 24304626 — Surrogate Endpoint (SUR): Blood pressure
Study 19609242 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19609242 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17464992 — Monitoring Biomarker (MOI): HBV DNA
Study 28600473 — Predictive Biomarker (PRD): HPV E2
Study 22084264 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12439840 — Surrogate Endpoint (SUR): Serum creatinine
Study 1934661 — Surrogate Endpoint (SUR): Serum creatinine
Study 8690819 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17686103 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 16366757 — Surrogate Endpoint (SUR): Blood pressure
Study 26537979 — Safety Biomarker (SAF): BDNF
Study 15647996 — Surrogate Endpoint (SUR): Bone mineral density
Study 8483425 — Surrogate Endpoint (SUR): Bone mineral density
Study 29289866 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24853255 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 15068496 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7653443 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7653443 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25948782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21596248 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 11182215 — Surrogate Endpoint (SUR): Blood pressure
Study 11127762 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8708167 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27358417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24614694 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24614694 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19641009 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31911526 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 31911526 — Surrogate Endpoint (SUR): Blood pressure
Study 23361846 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 23361846 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21809126 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 15638817 — Surrogate Endpoint (SUR): Blood pressure
Study 11937178 — Surrogate Endpoint (SUR): Blood pressure
Study 18312757 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 22209479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16271479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2095647 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30026002 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30026002 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 12464140 — Surrogate Endpoint (SUR): Blood pressure
Study 21345 — Surrogate Endpoint (SUR): Blood pressure
Study 26431466 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24474302 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30851097 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 24432675 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16382319 — Surrogate Endpoint (SUR): Bone mineral density
Study 16382319 — Surrogate Endpoint (SUR): Serum calcium
Study 9076205 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8322031 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 29074043 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 23988379 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20227099 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20227099 — Predictive Biomarker (PRD): IL17F
Genes: IL-17F; ML-1; ML1
Study 13677272 — Surrogate Endpoint (SUR): Blood pressure
Study 10372954 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25027585 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25027585 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 25027585 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25027585 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15890493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24233282 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21349594 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9587536 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21424279 — Surrogate Endpoint (SUR): Bone mineral density
Study 18504322 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16996879 — Surrogate Endpoint (SUR): Blood pressure
Study 18217908 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 18217908 — Surrogate Endpoint (SUR): Blood pressure
Study 19880675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11903939 — Surrogate Endpoint (SUR): Blood pressure
Study 9783498 — Surrogate Endpoint (SUR): Blood pressure
Study 23995795 — Predictive Biomarker (PRD): CYP27A1 mRNA
Genes: CYP27A1; CYP27
Study 23995795 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 22524633 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 24275013 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 14976046 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 24444783 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19074086 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 12571854 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12571854 — Surrogate Endpoint (SUR): Serum creatinine
Study 7700724 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 889511 — Surrogate Endpoint (SUR): Blood pressure
Study 24286591 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24286591 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 24286591 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 24286591 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24286591 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 24286591 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24286591 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22252613 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15857208 — Safety Biomarker (SAF): Reactive oxygen species
Study 30561849 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19058890 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 26143666 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18979616 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6499355 — Surrogate Endpoint (SUR): Blood pressure
Study 20384600 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 16625238 — Surrogate Endpoint (SUR): Blood pressure
Study 12856138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12856138 — Surrogate Endpoint (SUR): Blood pressure
Study 7687421 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 27585384 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 6752962 — Surrogate Endpoint (SUR): Blood pressure
Study 24367931 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study 24367931 — Predictive Biomarker (PRD): KIR2DL3 mRNA
Genes: KIR2DL3; CD158B2; KIRCL23; NKAT2
Study 18973991 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15956395 — Safety Biomarker (SAF): Cytoplasmic malate dehydrogenase
Genes: MDH1; MDHA
Study 10565591 — Predictive Biomarker (PRD): CLYBL mRNA
Genes: CLYBL; CLB
Study 22578446 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22578446 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 1875415 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18715665 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 18715665 — Monitoring Biomarker (MOI): HBV DNA
Study 14669615 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1