TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17468196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17468196 — Surrogate Endpoint (SUR): Serum testosterone
Study 10511068 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7589043 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 7589043 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25726210 — Predictive Biomarker (PRD): CHIA mRNA
Genes: CHIA
Study 388397 — Surrogate Endpoint (SUR): Blood pressure
Study 388397 — Surrogate Endpoint (SUR): Serum uric acid
Study 23379490 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 23379490 — Surrogate Endpoint (SUR): Serum calcium
Study 16954519 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 16954519 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 15458450 — Surrogate Endpoint (SUR): Serum creatinine
Study 15458450 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6099589 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29798256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8936398 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8936398 — Surrogate Endpoint (SUR): Blood pressure
Study 31178259 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31178259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31178259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28986166 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 28986166 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 22207250 — Surrogate Endpoint (SUR): Blood pressure
Study 1688013 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 28328847 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 26416412 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 26416412 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 2906019 — Surrogate Endpoint (SUR): Blood pressure
Study 2906019 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28635218 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study 23927913 — Surrogate Endpoint (SUR): Bone mineral density
Study 16754287 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 8891011 — Surrogate Endpoint (SUR): Serum creatinine
Study 1898717 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27364407 — Surrogate Endpoint (SUR): Blood pressure
Study 18451774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18451774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18451774 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25029567 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 24942646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24942646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20051951 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18034989 — Surrogate Endpoint (SUR): Blood pressure
Study 30794553 — Safety Biomarker (SAF): Hyaluronic acid
Study 24985000 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24985000 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24985000 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17213825 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22900524 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19074257 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19074257 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19074257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8648471 — Surrogate Endpoint (SUR): Blood pressure
Study 26906747 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 24039119 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26692322 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26692322 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 16809805 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 16809805 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8797414 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 8797414 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 8797414 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31170332 — Predictive Biomarker (PRD): B4GALNT3 mRNA
Genes: B4GALNT3
Study 31170332 — Predictive Biomarker (PRD): GALNT1 mRNA
Genes: GALNT1
Study 31170332 — Surrogate Endpoint (SUR): Bone mineral density
Study 22295535 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9357880 — Surrogate Endpoint (SUR): Blood pressure
Study 31251888 — Safety Biomarker (SAF): Reactive oxygen species
Study 22325170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9822001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15117110 — Surrogate Endpoint (SUR): Blood pressure
Study 7715220 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19710642 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 18069215 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25471080 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22304836 — Surrogate Endpoint (SUR): Blood pressure
Study 22304836 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19513811 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23043943 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 23043943 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 17894911 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15944796 — Predictive Biomarker (PRD): Microsatellite instability
Study 12858127 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12858127 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10232563 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 28541802 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 15502736 — Surrogate Endpoint (SUR): Bone mineral density
Study 15502736 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 21904088 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 19121433 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27457511 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21813223 — Surrogate Endpoint (SUR): Blood pressure
Study 2758453 — Surrogate Endpoint (SUR): Blood pressure
Study 28851784 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21062790 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17096501 — Safety Biomarker (SAF): Hyaluronic acid
Study 3514202 — Surrogate Endpoint (SUR): Serum calcium
Study 31394948 — Predictive Biomarker (PRD): PRPH2 mRNA
Genes: PRPH2; PRPH; RDS; TSPAN22
Study 24204067 — Surrogate Endpoint (SUR): Serum creatinine
Study 24204067 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24204067 — Surrogate Endpoint (SUR): Blood pressure
Study 18640826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16612448 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12531630 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 10951629 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 1426513 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28691417 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19620517 — Surrogate Endpoint (SUR): Blood pressure
Study 8360732 — Surrogate Endpoint (SUR): Blood pressure
Study 22210925 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 21351255 — Predictive Biomarker (PRD): EXOG mRNA
Genes: EXOG; ENDOGL1; ENDOGL2; ENGL
Study 21351255 — Predictive Biomarker (PRD): MT1G mRNA
Genes: MT1G; MT1K; MT1M
Study 16286438 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 8043977 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 8043977 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8043977 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8043977 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 29174310 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11057854 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23439301 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 11262572 — Surrogate Endpoint (SUR): Blood pressure
Study 8204876 — Safety Biomarker (SAF): Interleukin 1
Study 30350337 — Surrogate Endpoint (SUR): Blood pressure
Study 23681683 — Surrogate Endpoint (SUR): Blood pressure
Study 8860730 — Surrogate Endpoint (SUR): Blood pressure
Study 31753900 — Surrogate Endpoint (SUR): Blood pressure
Study 9935018 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 365537 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29463627 — Surrogate Endpoint (SUR): Blood pressure
Study 28078857 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28078857 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27871846 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 27871846 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 27871846 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27021566 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17552048 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 17552048 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17552048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9611008 — Predictive Biomarker (PRD): POMP mRNA
Genes: POMP; C13orf12; UMP1; HSPC014; HSPC036; PNAS-110
Study 25887378 — Surrogate Endpoint (SUR): Blood pressure
Study 9702436 — Safety Biomarker (SAF): Reactive oxygen species
Study 31102331 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 11289700 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11289700 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29289531 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 26551986 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26381715 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16627794 — Surrogate Endpoint (SUR): Blood pressure
Study 14596362 — Surrogate Endpoint (SUR): Blood pressure
Study 6540581 — Surrogate Endpoint (SUR): Blood pressure
Study 6540581 — Surrogate Endpoint (SUR): Serum creatinine
Study 26012640 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 26012640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15093878 — Surrogate Endpoint (SUR): Blood pressure
Study 11251731 — Surrogate Endpoint (SUR): Blood pressure
Study 16446318 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12582945 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 30267357 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 16351593 — Surrogate Endpoint (SUR): Blood pressure
Study 21062778 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 18430053 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18430053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18430053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15030296 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15030296 — Surrogate Endpoint (SUR): Blood pressure
Study 1586398 — Surrogate Endpoint (SUR): Blood pressure
Study 24500432 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 24500432 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 27803006 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 27803006 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27803006 — Predictive Biomarker (PRD): Hormone receptor
Study 19670959 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 15121119 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 3473681 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 23344474 — Surrogate Endpoint (SUR): Blood pressure
Study 9802618 — Predictive Biomarker (PRD): Hormone receptor
Study 18637053 — Monitoring Biomarker (MOI): HBV DNA
Study 2665546 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25675557 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22471559 — Surrogate Endpoint (SUR): Serum calcium
Study 22471559 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 14512295 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11673750 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9826861 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 25185971 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21852581 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21852581 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 21852581 — Surrogate Endpoint (SUR): Serum creatinine
Study 16713439 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16713439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2202853 — Surrogate Endpoint (SUR): Blood pressure
Study 6104255 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6104255 — Surrogate Endpoint (SUR): Serum uric acid
Study 17868728 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 3814462 — Surrogate Endpoint (SUR): Blood pressure
Study 9578184 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 9578184 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 11092233 — Surrogate Endpoint (SUR): Blood pressure
Study 1334101 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 1334101 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6418295 — Surrogate Endpoint (SUR): Blood pressure
Study 28646860 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 19483295 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 16920648 — Surrogate Endpoint (SUR): Blood pressure
Study 10639191 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 31837959 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 21389855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 14748999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8973979 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8973979 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 24375082 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 18331610 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 8308962 — Surrogate Endpoint (SUR): Serum creatinine
Study 26209642 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26209642 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19139031 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 17713165 — Monitoring Biomarker (MOI): HBV DNA
Study 15126801 — Surrogate Endpoint (SUR): Bone mineral density
Study 21375019 — Predictive Biomarker (PRD): SP8 mRNA
Genes: SP8
Study 21375019 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 1299500 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 6432001 — Surrogate Endpoint (SUR): Blood pressure
Study 27651882 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 19123156 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15970715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15970715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7895538 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27515478 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 23582934 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11739137 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8424427 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3687269 — Surrogate Endpoint (SUR): Blood pressure
Study 28735368 — Predictive Biomarker (PRD): TRIM32 mRNA
Genes: TRIM32; HT2A
Study 10037314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10037314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 48835 — Surrogate Endpoint (SUR): Blood pressure
Study 31139687 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 24187864 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 3556192 — Surrogate Endpoint (SUR): Blood pressure
Study 29239148 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27110823 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23687780 — Surrogate Endpoint (SUR): Blood pressure
Study 9228496 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15097237 — Surrogate Endpoint (SUR): Blood pressure
Study 29494423 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 29494423 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 27016718 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 23852294 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9273207 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1518258 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 30176897 — Predictive Biomarker (PRD): CPQ mRNA
Genes: CPQ; LCH1; PGCP
Study 18580611 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18580611 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9345406 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21593784 — Surrogate Endpoint (SUR): Blood pressure
Study 18820280 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 18820280 — Surrogate Endpoint (SUR): Serum calcium
Study 18820280 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8796137 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8796137 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 22137494 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8526788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31685553 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 31685553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3653758 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 31957889 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 29721623 — Surrogate Endpoint (SUR): Bone mineral density
Study 22251828 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 12850874 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30580469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22516265 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12417543 — Predictive Biomarker (PRD): NE
Study 12417543 — Surrogate Endpoint (SUR): Blood pressure
Study 28891024 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 28891024 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 28891024 — Predictive Biomarker (PRD): ACLY mRNA
Genes: ACLY
Study 28891024 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 28891024 — Predictive Biomarker (PRD): SLC2A2 mRNA
Genes: SLC2A2; GLUT2
Study 27228369 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 28073198 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24351403 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24351403 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 24351403 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18249325 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 18249325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18249325 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 18249325 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18249325 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12756219 — Surrogate Endpoint (SUR): Blood pressure
Study 19889807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1