TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20139391 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 20139391 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 16147905 — Surrogate Endpoint (SUR): Blood pressure
Study 1391736 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 9220214 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8345495 — Surrogate Endpoint (SUR): Blood pressure
Study 11557910 — Surrogate Endpoint (SUR): Blood pressure
Study 24938502 — Predictive Biomarker (PRD): NDRG1 mRNA
Genes: NDRG1; CAP43; DRG1; RTP
Study 22800889 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17698695 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17698695 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7002427 — Surrogate Endpoint (SUR): Blood pressure
Study 7002427 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30410041 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 28992296 — Surrogate Endpoint (SUR): Blood pressure
Study 19426116 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 19426116 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 17539025 — Monitoring Biomarker (MOI): HBV DNA
Study 18512710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17023704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8400756 — Surrogate Endpoint (SUR): Blood pressure
Study 31078666 — Surrogate Endpoint (SUR): Blood pressure
Study 21244590 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19631303 — Surrogate Endpoint (SUR): Bone mineral density
Study 27614458 — Surrogate Endpoint (SUR): Bone mineral density
Study 20413518 — Surrogate Endpoint (SUR): Serum creatinine
Study 12882849 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9206242 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3329516 — Surrogate Endpoint (SUR): Serum uric acid
Study 3329516 — Surrogate Endpoint (SUR): Blood pressure
Study 29782218 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29782218 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20728082 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9468008 — Surrogate Endpoint (SUR): Blood pressure
Study 356792 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26124351 — Predictive Biomarker (PRD): VEGFC mRNA
Genes: VEGFC
Study 26124351 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 26124351 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26124351 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11078841 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7514156 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7514156 — Surrogate Endpoint (SUR): Serum potassium
Study 30021626 — Surrogate Endpoint (SUR): Blood pressure
Study 30021626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20307245 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 20307245 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 18250501 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12797703 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 29519283 — Monitoring Biomarker (MOI): Procalcitonin
Study 29519283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29519283 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27614450 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27614450 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21389794 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 18484971 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6441544 — Surrogate Endpoint (SUR): Blood pressure
Study 31612844 — Surrogate Endpoint (SUR): Blood pressure
Study 27577516 — Safety Biomarker (SAF): XRCC1
Genes: RCC
Study 17426069 — Surrogate Endpoint (SUR): Blood pressure
Study 23483 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 23579036 — Safety Biomarker (SAF): Hyaluronic acid
Study 16330517 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30499426 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 27600862 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27600862 — Surrogate Endpoint (SUR): Blood pressure
Study 18760124 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 8813907 — Surrogate Endpoint (SUR): Serum potassium
Study 22562731 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22562731 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18564805 — Surrogate Endpoint (SUR): Blood pressure
Study 17893574 — Surrogate Endpoint (SUR): Blood pressure
Study 11474662 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11474662 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 9727378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9727378 — Safety Biomarker (SAF): IL-6 and IL-10
Study 7508536 — Surrogate Endpoint (SUR): Serum creatinine
Study 2837830 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 23622913 — Predictive Biomarker (PRD): PTMA mRNA
Genes: PTMA; TMSA
Study 7802981 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24274213 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 18469018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12565082 — Surrogate Endpoint (SUR): Blood pressure
Study 20151970 — Predictive Biomarker (PRD): PTGDS mRNA
Genes: PTGDS; PDS
Study 11195030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30098076 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30098076 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30098076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30098076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27767991 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 15591651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15591651 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 15591651 — Safety Biomarker (SAF): Interleukin 1
Study 15591651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8100910 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21872935 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21872935 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21872935 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12546311 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 10051936 — Surrogate Endpoint (SUR): Blood pressure
Study 7981577 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23353795 — Surrogate Endpoint (SUR): Blood pressure
Study 14707020 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7936476 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7936476 — Surrogate Endpoint (SUR): Blood pressure
Study 2847567 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26151924 — Safety Biomarker (SAF): BDNF
Study 23541756 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10027660 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8746863 — Surrogate Endpoint (SUR): Blood pressure
Study 23349882 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 21592048 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 18708299 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11043056 — Surrogate Endpoint (SUR): Blood pressure
Study 27633651 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 25057201 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 15678245 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 15678245 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 15678245 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10037839 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 10037839 — Surrogate Endpoint (SUR): Blood pressure
Study 8385284 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8385284 — Surrogate Endpoint (SUR): Blood pressure
Study 29345113 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22278627 — Surrogate Endpoint (SUR): Blood pressure
Study 20507582 — Surrogate Endpoint (SUR): Blood pressure
Study 15667660 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 12195131 — Surrogate Endpoint (SUR): Blood pressure
Study 2135068 — Surrogate Endpoint (SUR): Blood pressure
Study 6306388 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27711083 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27711083 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27711083 — Predictive Biomarker (PRD); Safety Biomarker (SAF): EGFR
Genes: ERBB1; ERRP
Study 27711083 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24702135 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22226086 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 8528053 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31856760 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21593283 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 18073779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18073779 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11418458 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11418458 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 19735512 — Safety Biomarker (SAF): Hyaluronic acid
Study 27348908 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 17980364 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 26786710 — Safety Biomarker (SAF): Hyaluronic acid
Study 23241328 — Predictive Biomarker (PRD): SPHK1 mRNA
Genes: SPHK1; SK1; SPHK; SPK
Study 3960242 — Surrogate Endpoint (SUR): Blood pressure
Study 3960242 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29555665 — Surrogate Endpoint (SUR): Blood pressure
Study 24999799 — Surrogate Endpoint (SUR): Blood pressure
Study 22884058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31574157 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 31248390 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 28347919 — Predictive Biomarker (PRD): ATG3 mRNA
Genes: ATG3; APG3; APG3L
Study 28347919 — Predictive Biomarker (PRD): UVRAG mRNA
Genes: UVRAG
Study 20381654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19126117 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 14749693 — Surrogate Endpoint (SUR): Blood pressure
Study 3125352 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23593205 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 24128861 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 24128861 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 16508640 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14631835 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 14631835 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14631835 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8436780 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26184986 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25236509 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 30900194 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 28544071 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17404163 — Surrogate Endpoint (SUR): Blood pressure
Study 17404163 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7554709 — Predictive Biomarker (PRD): MAOB mRNA
Genes: MAOB
Study 7797748 — Surrogate Endpoint (SUR): Blood pressure
Study 26242730 — Surrogate Endpoint (SUR): Blood pressure
Study 24217313 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12720535 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 3513531 — Surrogate Endpoint (SUR): Blood pressure
Study 24601174 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24601174 — Surrogate Endpoint (SUR): Blood pressure
Study 12730857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12730857 — Safety Biomarker (SAF): Interleukin 1
Study 25609562 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 18498809 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 18498809 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 18498809 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 18498809 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18498809 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 10648376 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26597598 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1360145 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27052530 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 27052530 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 22739534 — Predictive Biomarker (PRD): ABL2 mRNA
Genes: ABL2; ABLL; ARG
Study 20966444 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20966444 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9838911 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8028406 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30241001 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30241001 — Predictive Biomarker (PRD): Hormone receptor
Study 1727614 — Surrogate Endpoint (SUR): Serum creatinine
Study 18574086 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18574086 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9607554 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 9607554 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 9607554 — Surrogate Endpoint (SUR): Serum testosterone
Study 23835341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23835341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22692843 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 22692843 — Surrogate Endpoint (SUR): Bone mineral density
Study 17318036 — Surrogate Endpoint (SUR): Blood pressure
Study 15193831 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15193831 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30726962 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 31091611 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18337077 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16502116 — Surrogate Endpoint (SUR): Bone mineral density
Study 31914685 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 31914685 — Predictive Biomarker (PRD): NKRF mRNA
Genes: NKRF; ITBA4; NRF
Study 31914685 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22242712 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 17513327 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15727682 — Surrogate Endpoint (SUR): Bone mineral density
Study 9843546 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7515999 — Surrogate Endpoint (SUR): Blood pressure
Study 22676397 — Surrogate Endpoint (SUR): Blood pressure
Study 12585165 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12585165 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9105229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9105229 — Surrogate Endpoint (SUR): Serum creatinine
Study 31640092 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 28420440 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 28420440 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 18086061 — Safety Biomarker (SAF): Hyaluronic acid
Study 11718681 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10553820 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31451913 — Surrogate Endpoint (SUR): Bone mineral density
Study 21319007 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21319007 — Surrogate Endpoint (SUR): Bone mineral density
Study 17245174 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17245174 — Safety Biomarker (SAF): Cytochrome c
Study 17245174 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 11575894 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31838497 — Surrogate Endpoint (SUR): Blood pressure
Study 31838497 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25310510 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 8314287 — Surrogate Endpoint (SUR): Serum creatinine
Study 19794994 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12775734 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23062766 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 20669650 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 18562793 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 12456604 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 10479120 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8955652 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6309730 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 25093663 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 22928872 — Surrogate Endpoint (SUR): Blood pressure
Study 22928872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16180047 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16180047 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12153805 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 31537562 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 22314633 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 10690513 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 30028484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22322966 — Surrogate Endpoint (SUR): Blood pressure
Study 20196184 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16183427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10727880 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8855983 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 8855983 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8855983 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31214914 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27798337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22076016 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20061328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15983231 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 31402321 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31402321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31402321 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31402321 — Predictive Biomarker (PRD): Hormone receptor
Study 25210140 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 26156560 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 20119859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20119859 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 20119859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2