TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26338040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26338040 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22040533 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18596686 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 17692354 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22520250 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22076546 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 2160495 — Surrogate Endpoint (SUR): Blood pressure
Study 29976188 — Surrogate Endpoint (SUR): Blood pressure
Study 25626409 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 10894281 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6346848 — Surrogate Endpoint (SUR): Blood pressure
Study 26282583 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 26282583 — Surrogate Endpoint (SUR): Serum creatinine
Study 26282583 — Surrogate Endpoint (SUR): Blood pressure
Study 29982509 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18658112 — Predictive Biomarker (PRD): RSAD2 mRNA
Genes: RSAD2; CIG5
Study 12486431 — Surrogate Endpoint (SUR): Blood pressure
Study 3163879 — Surrogate Endpoint (SUR): Serum triglycerides
Study 3163879 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17548731 — Surrogate Endpoint (SUR): Blood pressure
Study 9539304 — Surrogate Endpoint (SUR): Urine free cortisol
Study 30942510 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20226444 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31324663 — Predictive Biomarker (PRD): SAGE1 mRNA
Genes: SAGE1; SAGE
Study 17451692 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11158948 — Surrogate Endpoint (SUR): Blood pressure
Study 3606869 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27590017 — Predictive Biomarker (PRD): INPP5K mRNA
Genes: INPP5K; PPS; SKIP
Study 25918759 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 23769121 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 23769121 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23769121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23769121 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 23769121 — Predictive Biomarker (PRD): JUN mRNA
Genes: JUN
Study 23769121 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23769121 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 19403877 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26580691 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 19211941 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8071049 — Surrogate Endpoint (SUR): Serum creatinine
Study 29253463 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28084056 — Predictive Biomarker (PRD): OPRD1 mRNA
Genes: OPRD1; OPRD
Study 28084056 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 28084056 — Predictive Biomarker (PRD): OPRK1 mRNA
Genes: OPRK1; OPRK
Study 10696631 — Surrogate Endpoint (SUR): Blood pressure
Study 10696631 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31331582 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 11059861 — Surrogate Endpoint (SUR): Serum creatinine
Study 19543195 — Surrogate Endpoint (SUR): Blood pressure
Study 17292412 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17292412 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 17292412 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 17292412 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 17292412 — Predictive Biomarker (PRD): KIR3DL1 mRNA
Genes: KIR3DL1; CD158E; NKAT3; NKB1
Study 17292412 — Predictive Biomarker (PRD): KLRD1 mRNA
Genes: KLRD1; CD94
Study 9088814 — Surrogate Endpoint (SUR): Blood pressure
Study 17020971 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study 1405316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1405316 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30823952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30823952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25366866 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17490862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12133054 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 30612325 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 30612325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30612325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20945114 — Surrogate Endpoint (SUR): Blood pressure
Study 19877063 — Surrogate Endpoint (SUR): Bone mineral density
Study 19877063 — Surrogate Endpoint (SUR): Serum calcium
Study 9233591 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9233591 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26045533 — Surrogate Endpoint (SUR): Blood pressure
Study 12398952 — Surrogate Endpoint (SUR): Bone mineral density
Study 1722834 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 30779119 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15966882 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12806591 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12806591 — Surrogate Endpoint (SUR): Blood pressure
Study 22984128 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 18497320 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 24569690 — Safety Biomarker (SAF): Interleukin 1
Study 20329654 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 20329654 — Surrogate Endpoint (SUR): Blood pressure
Study 27620990 — Surrogate Endpoint (SUR): Serum uric acid
Study 14691039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28830875 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26255512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26255512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25145323 — Surrogate Endpoint (SUR): Blood pressure
Study 23610100 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23610100 — Surrogate Endpoint (SUR): Serum calcium
Study 16579697 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 7942580 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24946155 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23349733 — Predictive Biomarker (PRD): CPT1B mRNA
Genes: CPT1B; KIAA1670
Study 23349733 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 23349733 — Surrogate Endpoint (SUR): Serum triglycerides
Study 1499145 — Surrogate Endpoint (SUR): Blood pressure
Study 31489188 — Surrogate Endpoint (SUR): Blood pressure
Study 23669062 — Surrogate Endpoint (SUR): Blood pressure
Study 29096836 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16935795 — Safety Biomarker (SAF): Hyaluronic acid
Study 25141100 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25141100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16350386 — Surrogate Endpoint (SUR): Blood pressure
Study 12135589 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7631051 — Surrogate Endpoint (SUR): Blood pressure
Study 7631051 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30610657 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15564706 — Surrogate Endpoint (SUR): Blood pressure
Study 15564706 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11460004 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7999471 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 27881559 — Surrogate Endpoint (SUR): Serum creatinine
Study 18296324 — Surrogate Endpoint (SUR): Bone mineral density
Study 16049208 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10383011 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 10383011 — Surrogate Endpoint (SUR): Serum calcium
Study 10383011 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 10383011 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29546669 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 29546669 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 24284444 — Surrogate Endpoint (SUR): Bone mineral density
Study 16314642 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 11923692 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 11923692 — Safety Biomarker (SAF): Interleukin 1
Study 11923692 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11923692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2404087 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 326847 — Surrogate Endpoint (SUR): Blood pressure
Study 26222126 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16332417 — Surrogate Endpoint (SUR): Bone mineral density
Study 11103221 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8267433 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27188329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27188329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15675976 — Surrogate Endpoint (SUR): Blood pressure
Study 17957097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17957097 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 17957097 — Safety Biomarker (SAF): Interleukin 1
Study 15014297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15014297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8175136 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29508247 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 29508247 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 29508247 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29508247 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 2258894 — Surrogate Endpoint (SUR): Blood pressure
Study 28215131 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 21625270 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 7976152 — Surrogate Endpoint (SUR): Blood pressure
Study 24034079 — Predictive Biomarker (PRD): NUBP1 mRNA
Genes: NUBP1; NBP; NBP1
Study 3914582 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 18929475 — Surrogate Endpoint (SUR): Blood pressure
Study 11081784 — Surrogate Endpoint (SUR): Blood pressure
Study 30355325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30355325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30355325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20056736 — Safety Biomarker (SAF): Reactive oxygen species
Study 20056736 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10231502 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26947523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20637969 — Surrogate Endpoint (SUR): Blood pressure
Study 17517804 — Surrogate Endpoint (SUR): Blood pressure
Study 8551469 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 22091534 — Surrogate Endpoint (SUR): Serum creatinine
Study 10673876 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 10673876 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23194084 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 14515196 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27733522 — Surrogate Endpoint (SUR): Blood pressure
Study 27733522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22782949 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 20075020 — Surrogate Endpoint (SUR): Blood pressure
Study 25386713 — Surrogate Endpoint (SUR): Bone mineral density
Study 15764851 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9648050 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 9648050 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 9648050 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20545689 — Predictive Biomarker (PRD): SCN8A mRNA
Genes: SCN8A; MED
Study 12089891 — Surrogate Endpoint (SUR): Blood pressure
Study 31809479 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 31132105 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 31132105 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 28789492 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23660206 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10674777 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27769273 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25315204 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23053638 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23053638 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23053638 — Surrogate Endpoint (SUR): Pathological complete response
Study 15342674 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 7736528 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 30670010 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30670010 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 30670010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30670010 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 30670010 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27193080 — Surrogate Endpoint (SUR): Blood pressure
Study 25311995 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 23090145 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8800584 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8800584 — Surrogate Endpoint (SUR): Blood pressure
Study 31027883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31027883 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31027883 — Surrogate Endpoint (SUR): Blood pressure
Study 31027883 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31027883 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31027883 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31027883 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 26947315 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22348233 — Surrogate Endpoint (SUR): Blood pressure
Study 18413426 — Surrogate Endpoint (SUR): Serum calcium
Study 15710045 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15710045 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 11831538 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15148924 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 6337004 — Surrogate Endpoint (SUR): Blood pressure
Study 24190860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24190860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20483364 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 3539030 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15866552 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26891677 — Surrogate Endpoint (SUR): Blood pressure
Study 19944580 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19944580 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 18035195 — Surrogate Endpoint (SUR): Blood pressure
Study 15672116 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6813126 — Surrogate Endpoint (SUR): Blood pressure
Study 17130267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17130267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17130267 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24569045 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16984938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16984938 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16984938 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 16984938 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 31833868 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17876365 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17876365 — Surrogate Endpoint (SUR): Blood pressure
Study 7917576 — Surrogate Endpoint (SUR): Bone mineral density
Study 2780070 — Surrogate Endpoint (SUR): Blood pressure
Study 31399446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11408847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11408847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16194620 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 3009726 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 24604243 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20189654 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 12131561 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12131561 — Surrogate Endpoint (SUR): Blood pressure
Study 9387637 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 6481116 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18154905 — Surrogate Endpoint (SUR): Blood pressure
Study 12181386 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27523583 — Surrogate Endpoint (SUR): Serum uric acid
Study 24366395 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22484777 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30099113 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 18309905 — Surrogate Endpoint (SUR): Blood pressure
Study 29917069 — Surrogate Endpoint (SUR): Blood pressure
Study 29917069 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18845972 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18845972 — Surrogate Endpoint (SUR): Blood pressure
Study 7475658 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 27452202 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 27452202 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24666814 — Surrogate Endpoint (SUR): Serum creatinine
Study 2532946 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 25776840 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 25776840 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 25776840 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17999779 — Predictive Biomarker (PRD): SMG1 mRNA
Genes: SMG1; ATX; KIAA0421; LIP
Study 17999779 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 17999779 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17999779 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9043725 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14513039 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 14513039 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 10994909 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 21291422 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 12734156 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19997751 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 10574653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8531542 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300