TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22898037 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 22898037 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19398921 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19398921 — Surrogate Endpoint (SUR): Bone mineral density
Study 25509728 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12861239 — Predictive Biomarker (PRD): APRT mRNA
Genes: APRT
Study 21565967 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18461212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18461212 — Surrogate Endpoint (SUR): Blood pressure
Study 1290019 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30144016 — Surrogate Endpoint (SUR): Blood pressure
Study 12151907 — Surrogate Endpoint (SUR): Blood pressure
Study 30278430 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30278430 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19210039 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19210039 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 16580587 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14508717 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26578543 — Predictive Biomarker (PRD): GCKR mRNA
Genes: GCKR
Study 26578543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22413836 — Surrogate Endpoint (SUR): Blood pressure
Study 20429947 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18241758 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 14613288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11549532 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 3415801 — Surrogate Endpoint (SUR): Blood pressure
Study 3415801 — Surrogate Endpoint (SUR): Serum testosterone
Study 16608770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16608770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7197960 — Surrogate Endpoint (SUR): Blood pressure
Study 28334675 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28334675 — Safety Biomarker (SAF): BDNF
Study 25987642 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 22948968 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20213082 — Predictive Biomarker (PRD): PAK1 mRNA
Genes: PAK1
Study 20213082 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17172317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11497194 — Surrogate Endpoint (SUR): Blood pressure
Study 31916514 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31669193 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 23499420 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 14961155 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 14961155 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 14961155 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24108314 — Surrogate Endpoint (SUR): Serum calcium
Study 21723949 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21723949 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 15546536 — Surrogate Endpoint (SUR): Blood pressure
Study 11208863 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11208863 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29879395 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 23067920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18568731 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31074876 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21487089 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9446265 — Surrogate Endpoint (SUR): Serum creatinine
Study 29315686 — Safety Biomarker (SAF): Reactive oxygen species
Study 18075758 — Predictive Biomarker (PRD): Hormone receptor
Study 18075758 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10928462 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10928462 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27898496 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27898496 — Predictive Biomarker (PRD): COMMD3 mRNA
Genes: COMMD3; BUP; C10orf8
Study 23591634 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 23591634 — Surrogate Endpoint (SUR): Bone mineral density
Study 23591634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23591634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9514186 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9514186 — Surrogate Endpoint (SUR): Blood pressure
Study 18052567 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18052567 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26761518 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26761518 — Safety Biomarker (SAF): Interleukin 12
Study 9314118 — Monitoring Biomarker (MOI): HBV DNA
Study 2427807 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2427807 — Surrogate Endpoint (SUR): Blood pressure
Study 28473924 — Surrogate Endpoint (SUR): Blood pressure
Study 10924606 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25727851 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16968848 — Surrogate Endpoint (SUR): Blood pressure
Study 9309626 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8312677 — Surrogate Endpoint (SUR): Blood pressure
Study 8312677 — Safety Biomarker (SAF): Urinary microalbumin
Study 8312677 — Surrogate Endpoint (SUR): Serum creatinine
Study 17345818 — Surrogate Endpoint (SUR): Bone mineral density
Study 1798594 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1798594 — Monitoring Biomarker (MOI): Complement C4
Study 30545718 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30545718 — Surrogate Endpoint (SUR): Blood pressure
Study 28988232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28988232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17237662 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 17237662 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 15566918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8659195 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 8659195 — Surrogate Endpoint (SUR): Blood pressure
Study 22978099 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22978099 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22978099 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20089449 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15604959 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 7571793 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26999197 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 27522059 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27522059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27522059 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 27522059 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27522059 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17215608 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11079660 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11079660 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11079660 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9348547 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 30249630 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18443573 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15977465 — Surrogate Endpoint (SUR): Bone mineral density
Study 15977465 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 14534616 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 31371391 — Predictive Biomarker (PRD): TRPV4 mRNA
Genes: TRPV4; VRL2; VROAC
Study 25600484 — Surrogate Endpoint (SUR): Bone mineral density
Study 30724760 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 27530911 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24906295 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 23279557 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15118290 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15943220 — Surrogate Endpoint (SUR): Blood pressure
Study 28486559 — Surrogate Endpoint (SUR): Blood pressure
Study 20482957 — Predictive Biomarker (PRD): OSR1 mRNA
Genes: OSR1; ODD
Study 14501599 — Surrogate Endpoint (SUR): Serum testosterone
Study 11103826 — Surrogate Endpoint (SUR): Blood pressure
Study 23185750 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23185750 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8257527 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 18197912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18197912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17313855 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11022077 — Safety Biomarker (SAF): MTHFR
Study 19463299 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10802396 — Surrogate Endpoint (SUR): Bone mineral density
Study 31407320 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 16531614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9380281 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 2864051 — Surrogate Endpoint (SUR): Blood pressure
Study 21865791 — Surrogate Endpoint (SUR): Blood pressure
Study 15199624 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9523211 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 7535842 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7535842 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 19558562 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 19558562 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19558562 — Predictive Biomarker (PRD): Microsatellite instability
Study 11176172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11176172 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30780126 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 20414671 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 17873673 — Predictive Biomarker (PRD): OGT mRNA
Genes: OGT
Study 17873673 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 9918893 — Surrogate Endpoint (SUR): Blood pressure
Study 7538412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23121249 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23121249 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 21697300 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17085985 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8378854 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 3005377 — Surrogate Endpoint (SUR): Blood pressure
Study 18315957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29581078 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26150543 — Surrogate Endpoint (SUR): Blood pressure
Study 17573449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17573449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17573449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12410058 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 2496619 — Surrogate Endpoint (SUR): Blood pressure
Study 23852061 — Surrogate Endpoint (SUR): Blood pressure
Study 18503607 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23395119 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12850965 — Surrogate Endpoint (SUR): Bone mineral density
Study 28453701 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19833861 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 19833861 — Predictive Biomarker (PRD): REEP5 mRNA
Genes: REEP5; C5orf18; DP1; TB2
Study 15154607 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 10631624 — Surrogate Endpoint (SUR): Blood pressure
Study 1373007 — Surrogate Endpoint (SUR): Blood pressure
Study 2857210 — Surrogate Endpoint (SUR): Serum potassium
Study 28515369 — Surrogate Endpoint (SUR): Blood pressure
Study 24634929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12834936 — Surrogate Endpoint (SUR): Blood pressure
Study 2764852 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31424713 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 18199805 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 11125309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29316213 — Surrogate Endpoint (SUR): Blood pressure
Study 18806039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25191766 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22027944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22027944 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18520980 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 10027435 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1828336 — Surrogate Endpoint (SUR): Blood pressure
Study 8637110 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1824653 — Surrogate Endpoint (SUR): Blood pressure
Study 24727871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24727871 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24727871 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 17612907 — Surrogate Endpoint (SUR): Blood pressure
Study 18515458 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 16685043 — Surrogate Endpoint (SUR): Blood pressure
Study 3312614 — Surrogate Endpoint (SUR): Blood pressure
Study 30142868 — Monitoring Biomarker (MOI): HBV DNA
Study 27723839 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27723839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24516190 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 11688904 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26493551 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 20338501 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20338501 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 25458446 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 18346173 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18346173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18346173 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12945222 — Surrogate Endpoint (SUR): Blood pressure
Study 24509980 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 17392668 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 21262880 — Surrogate Endpoint (SUR): Blood pressure
Study 8879340 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16670154 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 26884081 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24588813 — Surrogate Endpoint (SUR): Blood pressure
Study 18262041 — Surrogate Endpoint (SUR): Blood pressure
Study 12845425 — Surrogate Endpoint (SUR): Bone mineral density
Study 9597562 — Surrogate Endpoint (SUR): Blood pressure
Study 8165070 — Surrogate Endpoint (SUR): Blood pressure
Study 3210111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26580235 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 22872107 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31043691 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 31043691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21357374 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 21357374 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19603365 — Surrogate Endpoint (SUR): Bone mineral density
Study 17498484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17498484 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15136785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A1 mRNA
Genes: SRD5A1
Study 15136785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A2 mRNA
Genes: SRD5A2
Study 15136785 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 7997845 — Surrogate Endpoint (SUR): Blood pressure
Study 25593016 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25593016 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25593016 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 31527299 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 25833969 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23235355 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 23235355 — Surrogate Endpoint (SUR): Blood pressure
Study 19874586 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 18044102 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9631143 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16364165 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 3680600 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 12592681 — Monitoring Biomarker (MOI): HBV DNA
Study 30289802 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20660677 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 20660677 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12581507 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22982023 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study 22982023 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15990571 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11889577 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19901655 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 19901655 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15549369 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 15549369 — Surrogate Endpoint (SUR): Plasma ammonia
Study 24863486 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 15215483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24388167 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16085339 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 1899732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1899732 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25325116 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22627919 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 22627919 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 23923010 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1