TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15103751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15103751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15103751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15103751 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 15103751 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15103751 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25631070 — Surrogate Endpoint (SUR): Blood pressure
Study 20092179 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10836772 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28705993 — Predictive Biomarker (PRD): FIS1 mRNA
Genes: FIS1; TTC11; CGI-135
Study 28705993 — Predictive Biomarker (PRD): DNM1L mRNA
Genes: DNM1L; DLP1; DRP1
Study 28705993 — Predictive Biomarker (PRD): BNIP3 mRNA
Genes: BNIP3; NIP3
Study 26265643 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19735180 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19735180 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19735180 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15108768 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 10867596 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9112067 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 9112067 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9112067 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23689085 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20629109 — Predictive Biomarker (PRD): GSN mRNA
Genes: GSN
Study 27254807 — Safety Biomarker (SAF): Hyaluronic acid
Study 19934029 — Surrogate Endpoint (SUR): Blood pressure
Study 3073806 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31496537 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27822654 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 25471688 — Surrogate Endpoint (SUR): Blood pressure
Study 15532340 — Surrogate Endpoint (SUR): Blood pressure
Study 29370781 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26625004 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19636688 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 19636688 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 11730396 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8695558 — Predictive Biomarker (PRD): TNFRSF25 mRNA
Genes: TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; UNQ455/PRO779
Study 892957 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28087069 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 22117618 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19687781 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study 15482167 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15482167 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9289023 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9289023 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8513961 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23272529 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 23272529 — Surrogate Endpoint (SUR): Blood pressure
Study 20660805 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10441602 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7801862 — Surrogate Endpoint (SUR): Blood pressure
Study 30522886 — Surrogate Endpoint (SUR): Blood pressure
Study 8231902 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 8231902 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8231902 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 29105855 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29105855 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 29105855 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29105855 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 29105855 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 27259062 — Surrogate Endpoint (SUR): Blood pressure
Study 9008250 — Surrogate Endpoint (SUR): Blood pressure
Study 3234469 — Surrogate Endpoint (SUR): Blood pressure
Study 29948023 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22874110 — Surrogate Endpoint (SUR): Serum calcium
Study 22874110 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 27449643 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23469597 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 31232934 — Surrogate Endpoint (SUR): Blood pressure
Study 17559380 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 1824584 — Surrogate Endpoint (SUR): Blood pressure
Study 27187457 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7711146 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15679068 — Surrogate Endpoint (SUR): Bone mineral density
Study 12826145 — Surrogate Endpoint (SUR): Serum creatinine
Study 20163429 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 11839628 — Predictive Biomarker (PRD): ADAM10 mRNA
Genes: ADAM10; KUZ; MADM
Study 11839628 — Predictive Biomarker (PRD): ADAM15 mRNA
Genes: ADAM15; MDC15
Study 2076713 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2076713 — Surrogate Endpoint (SUR): Blood pressure
Study 31914241 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 31914241 — Predictive Biomarker (PRD): SMAD3 mRNA
Genes: SMAD3; MADH3
Study 20210904 — Surrogate Endpoint (SUR): Blood pressure
Study 10849894 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 10423609 — Surrogate Endpoint (SUR): Blood pressure
Study 27634943 — Surrogate Endpoint (SUR): Bone mineral density
Study 16013019 — Surrogate Endpoint (SUR): Serum potassium
Study 16013019 — Surrogate Endpoint (SUR): Serum sodium
Study 30130421 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 30130421 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 24962451 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 22879203 — Surrogate Endpoint (SUR): Serum testosterone
Study 12507837 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 2058612 — Surrogate Endpoint (SUR): Blood pressure
Study 10994859 — Surrogate Endpoint (SUR): Blood pressure
Study 20697090 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 16841663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2272259 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2272259 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28699041 — Surrogate Endpoint (SUR): Blood pressure
Study 25646170 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23824419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23824419 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11441134 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 373099 — Surrogate Endpoint (SUR): Blood pressure
Study 31149704 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19255890 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16499636 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 16499636 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 16499636 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16499636 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16499636 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12921816 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6356865 — Surrogate Endpoint (SUR): Blood pressure
Study 29024341 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-210
Genes: MIR210
Study 29024341 — Pharmacodynamic Biomarker (PDY): miR-132
Genes: MIR132
Study 29024341 — Monitoring Biomarker (MOI): miR-29a
Genes: MIR29A
Study 29024341 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-34a
Genes: MIR34A
Study 1755876 — Surrogate Endpoint (SUR): Blood pressure
Study 6314097 — Surrogate Endpoint (SUR): Blood pressure
Study 26853954 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21947680 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12218390 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20433751 — Surrogate Endpoint (SUR): Serum potassium
Study 15947903 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 11961396 — Surrogate Endpoint (SUR): Blood pressure
Study 7629406 — Surrogate Endpoint (SUR): Blood pressure
Study 20850953 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16957566 — Surrogate Endpoint (SUR): Blood pressure
Study 16957566 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16957566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16957566 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11728919 — Surrogate Endpoint (SUR): Bone mineral density
Study 24942404 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study 12631138 — Surrogate Endpoint (SUR): Blood pressure
Study 12631138 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27494722 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 11756072 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 25886875 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15492300 — Safety Biomarker (SAF): Reactive oxygen species
Study 15492300 — Surrogate Endpoint (SUR): Serum creatinine
Study 9744770 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31939321 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 30419153 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 31646578 — Predictive Biomarker (PRD): SOX9 mRNA
Genes: SOX9
Study 31646578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31646578 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31646578 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27931302 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15747154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15747154 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31027889 — Surrogate Endpoint (SUR): Blood pressure
Study 29977265 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29977265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29977265 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 26868369 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 31774956 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 31774956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15265001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15265001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15265001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24610884 — Surrogate Endpoint (SUR): Blood pressure
Study 23609390 — Surrogate Endpoint (SUR): Serum calcium
Study 792490 — Surrogate Endpoint (SUR): Blood pressure
Study 28381478 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 7940140 — Surrogate Endpoint (SUR): Blood pressure
Study 31614418 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26089641 — Surrogate Endpoint (SUR): Blood pressure
Study 7945575 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 27519791 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27519791 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27519791 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 27519791 — Monitoring Biomarker (MOI): Cell-free DNA
Study 20628590 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29100885 — Predictive Biomarker (PRD): MMP7 mRNA
Genes: MMP7; MPSL1; PUMP1
Study 23234151 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12824094 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12824094 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30099212 — Predictive Biomarker (PRD): MUL1 mRNA
Genes: MUL1; C1orf166; GIDE; MAPL; MULAN; RNF218
Study 23051558 — Surrogate Endpoint (SUR): Blood pressure
Study 30015069 — Surrogate Endpoint (SUR): Blood pressure
Study 21470279 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8225671 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30260748 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29734881 — Safety Biomarker (SAF): Reactive oxygen species
Study 29734881 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 17416761 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15037535 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15037535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8871871 — Monitoring Biomarker (MOI): HBV DNA
Study 26480904 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 26480904 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 18811878 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8855804 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 1535876 — Surrogate Endpoint (SUR): Serum creatinine
Study 6441778 — Surrogate Endpoint (SUR): Serum potassium
Study 31919514 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 23937708 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 20086023 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 11265008 — Surrogate Endpoint (SUR): Bone mineral density
Study 9539069 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9539069 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 5015048 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30824584 — Predictive Biomarker (PRD): MITF mRNA
Genes: MITF; BHLHE32
Study 30824584 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30824584 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 25774698 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9817170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11274244 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 11274244 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30179110 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30179110 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30179110 — Predictive Biomarker (PRD): Hormone receptor
Study 18156658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18156658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15955653 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28633627 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 26712979 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15191588 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12361815 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2000036 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6666227 — Surrogate Endpoint (SUR): Blood pressure
Study 29273847 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 18182457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26739717 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26739717 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 24472704 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 20718771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20718771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20718771 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20718771 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20718771 — Safety Biomarker (SAF): Interleukin 1
Study 20718771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20718771 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 20718771 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20718771 — Safety Biomarker (SAF): IL-6 and IL-10
Study 31685500 — Surrogate Endpoint (SUR): Blood pressure
Study 24550171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24550171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11252467 — Surrogate Endpoint (SUR): Serum creatinine
Study 8323210 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 21852813 — Surrogate Endpoint (SUR): Bone mineral density
Study 29445514 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 31423757 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 9731027 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 24148258 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study 19384265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 7605876 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 2083173 — Surrogate Endpoint (SUR): Blood pressure
Study 20069916 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15491984 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11158960 — Surrogate Endpoint (SUR): Blood pressure
Study 7929810 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2894883 — Surrogate Endpoint (SUR): Blood pressure
Study 29974143 — Surrogate Endpoint (SUR): Blood pressure
Study 23021797 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18800883 — Safety Biomarker (SAF): Reactive oxygen species
Study 15985101 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 15985101 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 12455318 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 7670399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7670399 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 29146743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29146743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20102894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20102894 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26886521 — Surrogate Endpoint (SUR): Serum testosterone
Study 18703803 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 15741530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12675867 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12675867 — Surrogate Endpoint (SUR): Blood pressure
Study 19590506 — Surrogate Endpoint (SUR): Blood pressure
Study 19590506 — Surrogate Endpoint (SUR): Serum uric acid
Study 2558700 — Surrogate Endpoint (SUR): Blood pressure
Study 2558700 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30985671 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 25760346 — Monitoring Biomarker (MOI): Procalcitonin
Study 15707477 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12622930 — Monitoring Biomarker (MOI): HBV DNA
Study 30690902 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 31237451 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 8505112 — Surrogate Endpoint (SUR): Blood pressure
Study 28316019 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 24043256 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET