TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17012105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12952774 — Surrogate Endpoint (SUR): Blood pressure
Study 8227469 — Surrogate Endpoint (SUR): Blood pressure
Study 26668251 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 22911148 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17359400 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 15182266 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 9675624 — Surrogate Endpoint (SUR): Blood pressure
Study 9675624 — Surrogate Endpoint (SUR): Serum potassium
Study 21566425 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11789281 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 11789281 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11789281 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26661319 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21439633 — Surrogate Endpoint (SUR): Blood pressure
Study 27172483 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 27172483 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study 25436769 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8770319 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25230866 — Monitoring Biomarker (MOI): Procalcitonin
Study 24802654 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7890059 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28439893 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 28439893 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 23972450 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15308881 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15308881 — Surrogate Endpoint (SUR): Blood pressure
Study 7406949 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30296404 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 30296404 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 28432376 — Surrogate Endpoint (SUR): Blood pressure
Study 24862330 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 6407293 — Surrogate Endpoint (SUR): Blood pressure
Study 11435967 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9740480 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9740480 — Surrogate Endpoint (SUR): Blood pressure
Study 2854116 — Surrogate Endpoint (SUR): Blood pressure
Study 23536132 — Surrogate Endpoint (SUR): Blood pressure
Study 12584828 — Monitoring Biomarker (MOI): HBV DNA
Study 10405773 — Surrogate Endpoint (SUR): Blood pressure
Study 6249334 — Surrogate Endpoint (SUR): Blood pressure
Study 15521893 — Surrogate Endpoint (SUR): Blood pressure
Study 26095263 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26095263 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11287757 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2122024 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25263393 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 19464401 — Surrogate Endpoint (SUR): Bone mineral density
Study 16518320 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 10910024 — Surrogate Endpoint (SUR): Blood pressure
Study 28985263 — Surrogate Endpoint (SUR): Blood pressure
Study 17823963 — Surrogate Endpoint (SUR): Blood pressure
Study 16648613 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9525349 — Surrogate Endpoint (SUR): Bone mineral density
Study 29703223 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 27598802 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22098260 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 22098260 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 17611249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9790077 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30610443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28074795 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22814896 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15262189 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 24378381 — Surrogate Endpoint (SUR): Bone mineral density
Study 12595861 — Predictive Biomarker (PRD): DUSP2 mRNA
Genes: DUSP2; PAC1
Study 16213288 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27405619 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 23652489 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23652489 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11455733 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 2899140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28830404 — Surrogate Endpoint (SUR): Blood pressure
Study 28830404 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28830404 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25503447 — Surrogate Endpoint (SUR): Blood pressure
Study 21368422 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 11336591 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 127471 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 31658975 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 30357438 — Surrogate Endpoint (SUR): Serum calcium
Study 28344144 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 23438932 — Surrogate Endpoint (SUR): Blood pressure
Study 8000036 — Surrogate Endpoint (SUR): Plasma ammonia
Study 16291717 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 16291717 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16291717 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16291717 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 7650334 — Monitoring Biomarker (MOI): HBV DNA
Study 28459931 — Surrogate Endpoint (SUR): Blood pressure
Study 28459931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28459931 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28459931 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21716078 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21716078 — Monitoring Biomarker (MOI): HBV DNA
Study 18287793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18287793 — Surrogate Endpoint (SUR): Sperm parameters
Study 18287793 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29284287 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 20806388 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 20806388 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11097197 — Surrogate Endpoint (SUR): Blood pressure
Study 1392491 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1392491 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1392491 — Surrogate Endpoint (SUR): Blood pressure
Study 3919522 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 22533654 — Surrogate Endpoint (SUR): Blood pressure
Study 22533654 — Surrogate Endpoint (SUR): Serum creatinine
Study 17851130 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 15818329 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31159537 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 28602413 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28602413 — Predictive Biomarker (PRD): ESR1
Genes: NR3A1; Era; ER-alpha
Study 20827284 — Surrogate Endpoint (SUR): Blood pressure
Study 31356514 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24138325 — Surrogate Endpoint (SUR): Blood pressure
Study 21388622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21388622 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8612031 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29861827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20339879 — Surrogate Endpoint (SUR): Blood pressure
Study 15935231 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 12771001 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 10801996 — Surrogate Endpoint (SUR): Blood pressure
Study 21310311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7931881 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 2887430 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 23463093 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 22123359 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22123359 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 1606596 — Surrogate Endpoint (SUR): Serum testosterone
Study 27197280 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20456744 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11225744 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11225744 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31255574 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10945489 — Predictive Biomarker (PRD): RNF135 mRNA
Genes: RNF135; L13
Study 3544622 — Surrogate Endpoint (SUR): Blood pressure
Study 22836602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21493741 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12649925 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30072176 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 1747702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25398660 — Safety Biomarker (SAF): Hyaluronic acid
Study 25398660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9185026 — Surrogate Endpoint (SUR): Blood pressure
Study 31626219 — Predictive Biomarker (PRD): SACS mRNA
Genes: SACS; KIAA0730
Study 8659732 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29985942 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29985942 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 29985942 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 29985942 — Predictive Biomarker (PRD): CCRL2 mRNA
Genes: CCRL2; CCR11; CCR6; CKRX; CRAM; HCR
Study 12461302 — Surrogate Endpoint (SUR): Blood pressure
Study 8761540 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 8761540 — Surrogate Endpoint (SUR): Serum calcium
Study 8761540 — Surrogate Endpoint (SUR): Serum phosphate
Study 8761540 — Surrogate Endpoint (SUR): Bone mineral density
Study 27070534 — Safety Biomarker (SAF): Hyaluronic acid
Study 10682151 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20608918 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 18087552 — Surrogate Endpoint (SUR): Blood pressure
Study 15476904 — Surrogate Endpoint (SUR): Blood pressure
Study 15476904 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25070447 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25070447 — Monitoring Biomarker (MOI): Procalcitonin
Study 11587162 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11587162 — Surrogate Endpoint (SUR): Blood pressure
Study 26069137 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26069137 — Surrogate Endpoint (SUR): Blood pressure
Study 28316072 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 28316072 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22921855 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22921855 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22921855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3303402 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17785764 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31801620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24569263 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24569263 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 16351563 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16351563 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10467966 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 2120362 — Surrogate Endpoint (SUR): Blood pressure
Study 30395687 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 26729347 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 20467151 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8723457 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 1401997 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30266575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30266575 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27051309 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15824849 — Surrogate Endpoint (SUR): Serum calcium
Study 31888744 — Safety Biomarker (SAF): IL-6 and IL-10
Study 26809984 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22372508 — Surrogate Endpoint (SUR): Blood pressure
Study 17208587 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7656958 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7656958 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30919638 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26241292 — Surrogate Endpoint (SUR): Blood pressure
Study 9797188 — Surrogate Endpoint (SUR): Blood pressure
Study 8634659 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 2758537 — Surrogate Endpoint (SUR): Blood pressure
Study 8484508 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3437794 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 3437794 — Monitoring Biomarker (MOI): HBV DNA
Study 23524841 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 19468757 — Surrogate Endpoint (SUR): Bone mineral density
Study 18317236 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 8156252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22262647 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22262647 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15930042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12027069 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9500317 — Surrogate Endpoint (SUR): Serum creatinine
Study 7886650 — Surrogate Endpoint (SUR): Serum potassium
Study 23736733 — Surrogate Endpoint (SUR): Blood pressure
Study 23736733 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11136171 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 3984837 — Surrogate Endpoint (SUR): Blood pressure
Study 30477827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30477827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30477827 — Surrogate Endpoint (SUR): Blood pressure
Study 22870258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10680840 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10680840 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21127897 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 9357093 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 2751753 — Surrogate Endpoint (SUR): Blood pressure
Study 999412 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 25666724 — Surrogate Endpoint (SUR): Bone mineral density
Study 19170847 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 24456217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12047485 — Surrogate Endpoint (SUR): Blood pressure
Study 7109499 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25149596 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 17472472 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11981081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10512898 — Surrogate Endpoint (SUR): Blood pressure
Study 23743741 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 15565596 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15565596 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12445025 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30496299 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 26399404 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19137863 — Surrogate Endpoint (SUR): Blood pressure
Study 10760336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7674882 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24511648 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18347680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3174724 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 29904824 — Surrogate Endpoint (SUR): Bone mineral density
Study 23175340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2679258 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 27790824 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31485864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22449201 — Predictive Biomarker (PRD): CPOX mRNA
Genes: CPOX; CPO; CPX
Study 22449201 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 22367664 — Surrogate Endpoint (SUR): Blood pressure
Study 2520637 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 19381522 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10912546 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 24252943 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 29940565 — Monitoring Biomarker (MOI): Cell-free DNA
Study 19654232 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19581770 — Monitoring Biomarker (MOI): HBV DNA
Study 17975845 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 25204361 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 23144466 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 23144466 — Surrogate Endpoint (SUR): Serum testosterone
Study 29202566 — Safety Biomarker (SAF): Hyaluronic acid
Study 25027139 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 19264840 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 11991558 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9203448 — Surrogate Endpoint (SUR): Blood pressure
Study 28592888 — Predictive Biomarker (PRD): TLX1 mRNA
Genes: TLX1; HOX11; TCL3
Study 28592888 — Predictive Biomarker (PRD): BARHL1 mRNA
Genes: BARHL1; FKSG31
Study 28592888 — Predictive Biomarker (PRD): BARX2 mRNA
Genes: BARX2
Study 28592888 — Predictive Biomarker (PRD): EMX2 mRNA
Genes: EMX2
Study 28592888 — Predictive Biomarker (PRD): LBX2 mRNA
Genes: LBX2; LP3727
Study 28592888 — Predictive Biomarker (PRD): MSX2 mRNA
Genes: MSX2; HOX8
Study 11087536 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 31004339 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ADAM11 mRNA
Genes: ADAM11; MDC
Study 8985623 — Surrogate Endpoint (SUR): Blood pressure
Study 27380342 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10616997 — Surrogate Endpoint (SUR): Blood pressure
Study 7488409 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 7488409 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 31365099 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28087235 — Surrogate Endpoint (SUR): Blood pressure
Study 11730275 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 11730275 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11730275 — Surrogate Endpoint (SUR): Blood pressure
Study 9570827 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21084429 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16186995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7353349 — Surrogate Endpoint (SUR): Blood pressure