TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11249900 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7686799 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 23521917 — Safety Biomarker (SAF): CD177 antigen
Genes: CD177; NB1; PRV1; UNQ595/PRO1181
Study 23521917 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 21849187 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21849187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30148436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30148436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23702263 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 23702263 — Predictive Biomarker (PRD): ARL2BP mRNA
Genes: ARL2BP; BART; BART1
Study 23702263 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 20979461 — Surrogate Endpoint (SUR): Blood pressure
Study 22970725 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20663275 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 2733993 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 27620647 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 23750500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1435800 — Monitoring Biomarker (MOI): HBV DNA
Study 31554419 — Predictive Biomarker (PRD): CXCL16 mRNA
Genes: CXCL16; SCYB16; SRPSOX; UNQ2759/PRO6714
Study 31554419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31554419 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27106640 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 11903320 — Surrogate Endpoint (SUR): Blood pressure
Study 20367631 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20367631 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 26910107 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 26910107 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 26910107 — Surrogate Endpoint (SUR): Blood pressure
Study 15345791 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10439645 — Surrogate Endpoint (SUR): Blood pressure
Study 25847 — Surrogate Endpoint (SUR): Blood pressure
Study 19058760 — Surrogate Endpoint (SUR): Blood pressure
Study 15028365 — Surrogate Endpoint (SUR): Blood pressure
Study 10999088 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 24165586 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 21890077 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19295193 — Surrogate Endpoint (SUR): Blood pressure
Study 15328386 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27741335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24740207 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 24740207 — Predictive Biomarker (PRD): ST6GALNAC3 mRNA
Genes: ST6GALNAC3; SIAT7C; UNQ2787/PRO7177
Study 8704095 — Safety Biomarker (SAF): Interleukin 1
Study 8704095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8704095 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 29672831 — Pharmacodynamic Biomarker (PDY): Nerve excitability testing
Study 26969416 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26969416 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22354851 — Surrogate Endpoint (SUR): Bone mineral density
Study 18724539 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 7843707 — Surrogate Endpoint (SUR): Serum creatinine
Study 2370508 — Surrogate Endpoint (SUR): Blood pressure
Study 15882556 — Surrogate Endpoint (SUR): Blood pressure
Study 7664215 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7664215 — Surrogate Endpoint (SUR): Blood pressure
Study 354042 — Surrogate Endpoint (SUR): Blood pressure
Study 12095953 — Surrogate Endpoint (SUR): Serum testosterone
Study 24754529 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 18412236 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 6961763 — Surrogate Endpoint (SUR): Blood pressure
Study 24633245 — Safety Biomarker (SAF): Hyaluronic acid
Study 16191116 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 16191116 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16191116 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7478121 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2105548 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24884651 — Predictive Biomarker (PRD): TNR mRNA
Genes: TNR
Study 23311172 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26800571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26800571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20378999 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20378999 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 17977544 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22734234 — Monitoring Biomarker (MOI): HBV DNA
Study 11134431 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2656331 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 27657997 — Predictive Biomarker (PRD): C1QTNF12 mRNA
Genes: C1QTNF12; C1QDC2; CTRP12; FAM132A
Study 24143092 — Safety Biomarker (SAF): Hyaluronic acid
Study 12060475 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 17507741 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 25978109 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14724101 — Predictive Biomarker (PRD): FAS mRNA
Genes: FAS; APT1; FAS1; TNFRSF6
Study 7495043 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31765932 — Surrogate Endpoint (SUR): Blood pressure
Study 29480853 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 29480853 — Surrogate Endpoint (SUR): Serum creatinine
Study 15726879 — Surrogate Endpoint (SUR): Blood pressure
Study 10403033 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8316057 — Surrogate Endpoint (SUR): Blood pressure
Study 27903994 — Surrogate Endpoint (SUR): Serum creatinine
Study 25661412 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 19068205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19068205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12627181 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10709813 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 8409784 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 27485109 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 27485109 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 19909829 — Surrogate Endpoint (SUR): Bone mineral density
Study 12459940 — Surrogate Endpoint (SUR): Bone mineral density
Study 1503823 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24613450 — Surrogate Endpoint (SUR): Bone mineral density
Study 22588319 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11826199 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10519745 — Surrogate Endpoint (SUR): Blood pressure
Study 24549598 — Predictive Biomarker (PRD): PIK3CD mRNA
Genes: PIK3CD
Study 15842464 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 23975656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19327625 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27237059 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25509731 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15808245 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 6365467 — Surrogate Endpoint (SUR): Blood pressure
Study 30807430 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 30807430 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 27821627 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27821627 — Surrogate Endpoint (SUR): Serum creatinine
Study 19926050 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19926050 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 15566594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21957667 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 19661012 — Surrogate Endpoint (SUR): Blood pressure
Study 16935462 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24816038 — Predictive Biomarker (PRD): TENM4 mRNA
Genes: TENM4; KIAA1302; ODZ4; TNM4
Study 11493736 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31785250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31785250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31785250 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17012108 — Surrogate Endpoint (SUR): Bone mineral density
Study 30686699 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21172721 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24786143 — Surrogate Endpoint (SUR): Serum creatinine
Study 10371778 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 8902990 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8902990 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 6352036 — Surrogate Endpoint (SUR): Blood pressure
Study 21290831 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12521402 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12521402 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1778538 — Surrogate Endpoint (SUR): Blood pressure
Study 30707227 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28424187 — Surrogate Endpoint (SUR): Blood pressure
Study 21931661 — Predictive Biomarker (PRD): TACR1 mRNA
Genes: TACR1; NK1R; TAC1R
Study 21931661 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 21931661 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19150179 — Surrogate Endpoint (SUR): Blood pressure
Study 29339351 — Surrogate Endpoint (SUR): Blood pressure
Study 26894485 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15939582 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 15939582 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 15939582 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9004249 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9004249 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 1627424 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20844485 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 10725985 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10725985 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10725985 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1688988 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 6992186 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 6992186 — Surrogate Endpoint (SUR): Blood pressure
Study 27507930 — Surrogate Endpoint (SUR): Blood pressure
Study 23751742 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 20834185 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15803314 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7851579 — Surrogate Endpoint (SUR): Blood pressure
Study 18704426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15528877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15528877 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9309627 — Surrogate Endpoint (SUR): Blood pressure
Study 26991399 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22796949 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 10929792 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8765493 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31975536 — Surrogate Endpoint (SUR): Blood pressure
Study 27664111 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 27664111 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 14695462 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 14695462 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2338687 — Surrogate Endpoint (SUR): Blood pressure
Study 19298406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19298406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19298406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8143059 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11315832 — Surrogate Endpoint (SUR): Blood pressure
Study 28582848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28582848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28582848 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28582848 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28582848 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 28582848 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 2679039 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study 6989171 — Surrogate Endpoint (SUR): Bone mineral density
Study 31638680 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 24384420 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1735251 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23606339 — Surrogate Endpoint (SUR): Blood pressure
Study 21556366 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 21556366 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21556366 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study 20878622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 14520444 — Surrogate Endpoint (SUR): Serum creatinine
Study 27644589 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24236174 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24236174 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 24236174 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 24191286 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 20376430 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1826911 — Surrogate Endpoint (SUR): Blood pressure
Study 27625142 — Surrogate Endpoint (SUR): Blood pressure
Study 15560807 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 2884895 — Surrogate Endpoint (SUR): Blood pressure
Study 18797670 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 11239222 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21750157 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21750157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21750157 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26160958 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 26160958 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16467972 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 16467972 — Surrogate Endpoint (SUR): Bone mineral density
Study 24332142 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22418773 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 20532178 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8588965 — Surrogate Endpoint (SUR): Blood pressure
Study 25123256 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 25123256 — Surrogate Endpoint (SUR): Blood pressure
Study 12775969 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 8654655 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20626053 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26105008 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 26105008 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 26105008 — Safety Biomarker (SAF): Reactive oxygen species
Study 17365745 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 15128636 — Surrogate Endpoint (SUR): Blood pressure
Study 3243221 — Surrogate Endpoint (SUR): Blood pressure
Study 19672771 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 15100717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7508827 — Surrogate Endpoint (SUR): Serum potassium
Study 2906956 — Surrogate Endpoint (SUR): Blood pressure
Study 24726210 — Surrogate Endpoint (SUR): Serum potassium
Study 18422677 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22631051 — Surrogate Endpoint (SUR): Blood pressure
Study 2854886 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31983034 — Surrogate Endpoint (SUR): Bone mineral density
Study 31310442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23525894 — Surrogate Endpoint (SUR): Bone mineral density
Study 27058907 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27058907 — Surrogate Endpoint (SUR): Blood pressure
Study 22824755 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 22824755 — Safety Biomarker (SAF): Reactive oxygen species
Study 15956086 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9564059 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 9564059 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26828618 — Surrogate Endpoint (SUR): Bone mineral density
Study 18701019 — Surrogate Endpoint (SUR): Blood pressure
Study 18701019 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12870698 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 3886398 — Surrogate Endpoint (SUR): Serum potassium
Study 3886398 — Surrogate Endpoint (SUR): Serum sodium
Study 16034009 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15149345 — Surrogate Endpoint (SUR): Serum creatinine
Study 15149345 — Surrogate Endpoint (SUR): Blood pressure
Study 23474436 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23474436 — Surrogate Endpoint (SUR): Serum testosterone
Study 21457567 — Surrogate Endpoint (SUR): Blood pressure
Study 19041437 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19041437 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16412866 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 16412866 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16412866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9783532 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15004731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15004731 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31227385 — Surrogate Endpoint (SUR): Blood pressure
Study 23642733 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19954711 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 10658944 — Surrogate Endpoint (SUR): Blood pressure
Study 31241784 — Surrogate Endpoint (SUR): Probing pocket depth
Study 20559104 — Predictive Biomarker (PRD): MPG mRNA
Genes: MPG; AAG; ANPG; MID1
Study 30961672 — Predictive Biomarker (PRD): ABCA4 mRNA
Genes: ABCA4; ABCR
Study 23404154 — Surrogate Endpoint (SUR): Blood pressure
Study 12929879 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 1357124 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29063186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18798830 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 10428581 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31479722 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31479722 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28689179 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 28689179 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351