TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29652246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23949961 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23949961 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8894914 — Surrogate Endpoint (SUR): Blood pressure
Study 1503282 — Surrogate Endpoint (SUR): Blood pressure
Study 29233588 — Monitoring Biomarker (MOI): miR-99b
Genes: MIR99B
Study 29233588 — Safety Biomarker (SAF): miR-423
Genes: MIR423
Study 29233588 — Predictive Biomarker (PRD): let-7c
Genes: MIRLET7C
Study 30344165 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 27770771 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 46951 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1832701 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1832701 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6227208 — Surrogate Endpoint (SUR): Blood pressure
Study 31527690 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31527690 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31527690 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21853290 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21853290 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11877767 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21926656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17379842 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 415471 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27696656 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 27696656 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 25680375 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 19387331 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 9636912 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9636912 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7872715 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26301701 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 29596158 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22648092 — Surrogate Endpoint (SUR): Blood pressure
Study 22648092 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12551863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31933439 — Predictive Biomarker (PRD): C6orf15 mRNA
Genes: C6orf15; STG; UNQ1840/PRO3566
Study 24997757 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15089890 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 22013105 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22013105 — Safety Biomarker (SAF): Reactive oxygen species
Study 22013105 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22013105 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23382325 — Surrogate Endpoint (SUR): Blood pressure
Study 15614026 — Surrogate Endpoint (SUR): Blood pressure
Study 11724449 — Surrogate Endpoint (SUR): Blood pressure
Study 2462444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15696321 — Surrogate Endpoint (SUR): Blood pressure
Study 25536308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25536308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24565455 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24590363 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 1932647 — Surrogate Endpoint (SUR): Blood pressure
Study 16774821 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12730756 — Surrogate Endpoint (SUR): Bone mineral density
Study 21795429 — Surrogate Endpoint (SUR): Blood pressure
Study 21795429 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 29277297 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 29277297 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23585468 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 23585468 — Surrogate Endpoint (SUR): Serum testosterone
Study 20573223 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 8970247 — Surrogate Endpoint (SUR): Blood pressure
Study 1468826 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29034453 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 23193843 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18396107 — Surrogate Endpoint (SUR): Blood pressure
Study 15573384 — Predictive Biomarker (PRD): ST8SIA4 mRNA
Genes: ST8SIA4; PST; PST1; SIAT8D
Study 12008175 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3565526 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 23609777 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29389068 — Surrogate Endpoint (SUR): Serum sodium
Study 26560898 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 26560898 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15733508 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2223528 — Surrogate Endpoint (SUR): Blood pressure
Study 17313720 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11772795 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11772795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7861714 — Surrogate Endpoint (SUR): Serum creatinine
Study 23679192 — Predictive Biomarker (PRD): Hormone receptor
Study 23679192 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12189360 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31884472 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 31884472 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28347654 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28347654 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21834061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17461857 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15651747 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15651747 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 11269571 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23687260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1962596 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28235537 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27923389 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27923389 — Surrogate Endpoint (SUR): Blood pressure
Study 24438432 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24438432 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9038445 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6238910 — Surrogate Endpoint (SUR): Blood pressure
Study 17535827 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 24471477 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29981855 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25342896 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 20502405 — Surrogate Endpoint (SUR): Bone mineral density
Study 17478952 — Surrogate Endpoint (SUR): Blood pressure
Study 26234554 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8814503 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1348751 — Surrogate Endpoint (SUR): Blood pressure
Study 11426091 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11426091 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 11426091 — Surrogate Endpoint (SUR): Blood pressure
Study 27803392 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 22407197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1359808 — Surrogate Endpoint (SUR): Blood pressure
Study 8681492 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28222251 — Predictive Biomarker (PRD): LZTS2 mRNA
Genes: LZTS2; KIAA1813; LAPSER1
Study 28222251 — Predictive Biomarker (PRD): NR6A1 mRNA
Genes: NR6A1; GCNF
Study 30037726 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 30037726 — Surrogate Endpoint (SUR): Blood pressure
Study 23414904 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16331300 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16331300 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14668779 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 10321931 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27578231 — Surrogate Endpoint (SUR): Blood pressure
Study 7572698 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1951552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31267965 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 28254171 — Surrogate Endpoint (SUR): Blood pressure
Study 17095643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20361330 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19604597 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 23535700 — Surrogate Endpoint (SUR): Blood pressure
Study 19880462 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 12525441 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8948238 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2415436 — Monitoring Biomarker (MOI): HBV DNA
Study 20052524 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 16032522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16032522 — Surrogate Endpoint (SUR): Blood pressure
Study 1925896 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1925896 — Predictive Biomarker (PRD): Hormone receptor
Study 6918220 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27422890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27422890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31418329 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 27774917 — Surrogate Endpoint (SUR): Blood pressure
Study 15613414 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7658178 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2711539 — Surrogate Endpoint (SUR): Blood pressure
Study 1148032 — Surrogate Endpoint (SUR): Serum uric acid
Study 7933528 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 15601388 — Surrogate Endpoint (SUR): Blood pressure
Study 9533929 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 30485516 — Surrogate Endpoint (SUR): Blood pressure
Study 25264665 — Surrogate Endpoint (SUR): Blood pressure
Study 16728648 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study 15237695 — Surrogate Endpoint (SUR): Blood pressure
Study 22549879 — Safety Biomarker (SAF): Interleukin 1
Study 10608295 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23932821 — Surrogate Endpoint (SUR): Serum creatinine
Study 12959951 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 12833107 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8784750 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 6419709 — Surrogate Endpoint (SUR): Plasma testosterone level
Study 31158087 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 3541816 — Surrogate Endpoint (SUR): Blood pressure
Study 25478537 — Surrogate Endpoint (SUR): Blood pressure
Study 16425390 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8896506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8896506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17884510 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 16301343 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11039606 — Predictive Biomarker (PRD): SPINK1 mRNA
Genes: SPINK1; PSTI
Study 11039606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2218733 — Surrogate Endpoint (SUR): Blood pressure
Study 28864219 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 23503480 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17014579 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17947609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17947609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17947609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15617993 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15617993 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 30396622 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 30601336 — Monitoring Biomarker (MOI): HBV DNA
Study 27364375 — Surrogate Endpoint (SUR): Bone mineral density
Study 24247554 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15181047 — Surrogate Endpoint (SUR): Blood pressure
Study 15181047 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11069440 — Surrogate Endpoint (SUR): Blood pressure
Study 25494594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25494594 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15714983 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11051123 — Predictive Biomarker (PRD): SULT1A3 mRNA
Genes: SULT1A3; STM
Study 3890395 — Surrogate Endpoint (SUR): Blood pressure
Study 29419569 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 15225828 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 15225828 — Surrogate Endpoint (SUR): Bone mineral density
Study 26223257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26223257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26223257 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9435323 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27710808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18679601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31476911 — Surrogate Endpoint (SUR): Blood pressure
Study 27077973 — Surrogate Endpoint (SUR): Blood pressure
Study 16052058 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25833063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25833063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25833063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25833063 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19524243 — Surrogate Endpoint (SUR): Blood pressure
Study 19524243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19524243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19524243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11371418 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 8289986 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 8289986 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 8289986 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 2060542 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27208982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26597879 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 26597879 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 22492479 — Surrogate Endpoint (SUR): Bone mineral density
Study 12206997 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 10566553 — Predictive Biomarker (PRD): RAB11FIP1 mRNA
Genes: RAB11FIP1; RCP
Study 10566553 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 2006653 — Surrogate Endpoint (SUR): Blood pressure
Study 9708225 — Surrogate Endpoint (SUR): Bone mineral density
Study 28901116 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15604328 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15604328 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15604328 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31229857 — Predictive Biomarker (PRD): Hormone receptor
Study 28384752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21297491 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 8850405 — Safety Biomarker (SAF): 51Cr-EDTA
Study 16939523 — Surrogate Endpoint (SUR): Serum creatinine
Study 15472204 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11576570 — Surrogate Endpoint (SUR): Bone mineral density
Study 26607848 — Surrogate Endpoint (SUR): Blood pressure
Study 24047916 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 24047916 — Surrogate Endpoint (SUR): Bone mineral density
Study 19515530 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1327630 — Surrogate Endpoint (SUR): Blood pressure
Study 30548692 — Surrogate Endpoint (SUR): Blood pressure
Study 29450494 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29450494 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24568917 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9698276 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9698276 — Monitoring Biomarker (MOI): Complement C4
Study 23038624 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 23038624 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 23038624 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 23038624 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 23038624 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 23038624 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 19538732 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19538732 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 9056681 — Surrogate Endpoint (SUR): Blood pressure
Study 23271912 — Surrogate Endpoint (SUR): Blood pressure
Study 27522437 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22442277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18401017 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1354494 — Surrogate Endpoint (SUR): Blood pressure
Study 26986104 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24176681 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 24176681 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 19015925 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17429539 — Monitoring Biomarker (MOI): HBV DNA
Study 11144694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 8695136 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8695136 — Surrogate Endpoint (SUR): Blood pressure
Study 16616662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16616662 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10527954 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 10527954 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 8892515 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27681760 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 12032876 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25736101 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7517238 — Surrogate Endpoint (SUR): Blood pressure