TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22444781 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22444781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26834282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20811299 — Surrogate Endpoint (SUR): Blood pressure
Study 20811299 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20811299 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2276936 — Surrogate Endpoint (SUR): Blood pressure
Study 11454528 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11454528 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 9875837 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3293399 — Surrogate Endpoint (SUR): Blood pressure
Study 29482720 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 26358841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26358841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26358841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24751388 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 11465644 — Surrogate Endpoint (SUR): Blood pressure
Study 30736873 — Surrogate Endpoint (SUR): Blood pressure
Study 19361589 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19361589 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16626943 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 11461714 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 28251260 — Predictive Biomarker (PRD): MAVS mRNA
Genes: MAVS; IPS1; KIAA1271; VISA
Study 12671332 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12671332 — Surrogate Endpoint (SUR): Blood pressure
Study 8857906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30360498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26892312 — Surrogate Endpoint (SUR): Blood pressure
Study 22412842 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22412842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19281600 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 22169414 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19494028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16340945 — Surrogate Endpoint (SUR): Blood pressure
Study 31592887 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25993609 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 16226864 — Surrogate Endpoint (SUR): Blood pressure
Study 12634979 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12634979 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27553419 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22911473 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 11862365 — Surrogate Endpoint (SUR): Blood pressure
Study 24736085 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22332206 — Surrogate Endpoint (SUR): Blood pressure
Study 17975233 — Predictive Biomarker (PRD): BCL2A1 mRNA
Genes: BCL2A1; BCL2L5; BFL1; GRS; HBPA1
Study 15772061 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 29123173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29123173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29123173 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 29123173 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26025336 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 24302008 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17890493 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 11932287 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 11932287 — Surrogate Endpoint (SUR): Bone mineral density
Study 8583465 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8583465 — Surrogate Endpoint (SUR): Blood pressure
Study 30681017 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 21872282 — Surrogate Endpoint (SUR): Serum creatinine
Study 15122768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11496318 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 9792263 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30636725 — Predictive Biomarker (PRD): ALKBH1 mRNA
Genes: ALKBH1; ABH; ABH1; ALKBH
Study 27268381 — Surrogate Endpoint (SUR): Blood pressure
Study 26047975 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 15514501 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 15514501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2675952 — Surrogate Endpoint (SUR): Blood pressure
Study 27819756 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21896129 — Safety Biomarker (SAF): Hyaluronic acid
Study 11269462 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9505147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2468872 — Surrogate Endpoint (SUR): Blood pressure
Study 26711317 — Predictive Biomarker (PRD): NRTN mRNA
Genes: NRTN
Study 25349302 — Predictive Biomarker (PRD): Hormone receptor
Study 22537222 — Surrogate Endpoint (SUR): Blood pressure
Study 17326076 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 31975496 — Surrogate Endpoint (SUR): Blood pressure
Study 18756431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30111357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22539584 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 17907110 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17907110 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 17907110 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17907110 — Surrogate Endpoint (SUR): Serum creatinine
Study 25315022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9101193 — Surrogate Endpoint (SUR): Blood pressure
Study 29316405 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29850709 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27565010 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22828021 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 14711543 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 11403366 — Surrogate Endpoint (SUR): Blood pressure
Study 24731467 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24731467 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16638934 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 16638934 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 14719287 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 8658373 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17949673 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15827560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15827560 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12107508 — Surrogate Endpoint (SUR): Blood pressure
Study 12107508 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2653095 — Surrogate Endpoint (SUR): Blood pressure
Study 15758010 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 2287773 — Surrogate Endpoint (SUR): Serum creatinine
Study 11216737 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28927636 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 26874946 — Surrogate Endpoint (SUR): Serum creatinine
Study 26874946 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18248644 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16758262 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 16758262 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2439833 — Surrogate Endpoint (SUR): Blood pressure
Study 16409195 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 16409195 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 21494052 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 16459509 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 12638098 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 10229295 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1878335 — Surrogate Endpoint (SUR): Blood pressure
Study 27533157 — Surrogate Endpoint (SUR): Bone mineral density
Study 27533157 — Surrogate Endpoint (SUR): New morphometric vertebral fractures
Study 19452124 — Surrogate Endpoint (SUR): Bone mineral density
Study 3349432 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30676196 — Surrogate Endpoint (SUR): Blood pressure
Study 25921846 — Predictive Biomarker (PRD): ABCG8 mRNA
Genes: ABCG8
Study 23032071 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 21775748 — Surrogate Endpoint (SUR): Blood pressure
Study 11114135 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21102493 — Surrogate Endpoint (SUR): Blood pressure
Study 16907704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16907704 — Predictive Biomarker (PRD): NOD2 mRNA
Genes: NOD2; CARD15; IBD1
Study 16907704 — Predictive Biomarker (PRD): IRAK1 mRNA
Genes: IRAK1; IRAK
Study 16907704 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 16907704 — Predictive Biomarker (PRD): LY86 mRNA
Genes: LY86; MD1
Study 16907704 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study 16907704 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 16907704 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 16907704 — Predictive Biomarker (PRD): NFKB1 mRNA
Genes: NFKB1
Study 21672053 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 24229770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12960598 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 30773300 — Predictive Biomarker (PRD): ADORA2A mRNA
Genes: ADORA2A; ADORA2
Study 30773300 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 30773300 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 21519745 — Surrogate Endpoint (SUR): Blood pressure
Study 10801247 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31877766 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 21246373 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20672352 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 7893586 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 7893586 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25636934 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 24323795 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 8650034 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 8650034 — Surrogate Endpoint (SUR): Blood pressure
Study 20193083 — Surrogate Endpoint (SUR): Bone mineral density
Study 7537116 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7537116 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 7537116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7537116 — Safety Biomarker (SAF): Interleukin 1
Study 7537116 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22018993 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11143776 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11143776 — Surrogate Endpoint (SUR): Blood pressure
Study 23834197 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1399498 — Surrogate Endpoint (SUR): Blood pressure
Study 27250349 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 20382859 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20382859 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20382859 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 20382859 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 20382859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18924053 — Surrogate Endpoint (SUR): Blood pressure
Study 8476892 — Surrogate Endpoint (SUR): Serum creatinine
Study 24493100 — Surrogate Endpoint (SUR): Blood pressure
Study 24493100 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2972209 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28929131 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 28929131 — Safety Biomarker (SAF): DRD2
Study 28982550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28982550 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 26717658 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26717658 — Surrogate Endpoint (SUR): Serum sodium
Study 26717658 — Surrogate Endpoint (SUR): Blood pressure
Study 20606833 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16054717 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12842527 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12842527 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12842527 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9887063 — Predictive Biomarker (PRD): Phospholipase A2 inhibitory protein
Genes: ANXA1; ANX1; LPC1
Study 7173300 — Surrogate Endpoint (SUR): Blood pressure
Study 30307821 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30307821 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25193991 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 25193991 — Predictive Biomarker (PRD): FGF3 mRNA
Genes: FGF3; INT2
Study 25193991 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25193991 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 25193991 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15071275 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11205195 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 29617976 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24021824 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24021824 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15547162 — Surrogate Endpoint (SUR): Blood pressure
Study 27399735 — Surrogate Endpoint (SUR): Blood pressure
Study 18175742 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 18175742 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30815856 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 16502725 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 31350585 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 17309916 — Surrogate Endpoint (SUR): Serum creatinine
Study 15381546 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17668563 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15819377 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15819377 — Surrogate Endpoint (SUR): Blood pressure
Study 9571355 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9571355 — Surrogate Endpoint (SUR): Blood pressure
Study 31478415 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27382685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20368559 — Predictive Biomarker (PRD): Hormone receptor
Study 9261860 — Surrogate Endpoint (SUR): Blood pressure
Study 8501488 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 3030087 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3030087 — Surrogate Endpoint (SUR): Blood pressure
Study 3030087 — Surrogate Endpoint (SUR): Serum sodium
Study 14624167 — Surrogate Endpoint (SUR): Blood pressure
Study 22659666 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 9302344 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29655829 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24755993 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24755993 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CHRM2 mRNA
Genes: CHRM2
Study 24755993 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 24755993 — Safety Biomarker (SAF): BDNF
Study 20720257 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 20720257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3903336 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 12895159 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31592825 — Safety Biomarker (SAF): Hyaluronic acid
Study 31747862 — Predictive Biomarker (PRD): NOS1AP mRNA
Genes: NOS1AP; CAPON; KIAA0464
Study 24970885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19850347 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19850347 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 7937786 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2908716 — Surrogate Endpoint (SUR): Blood pressure
Study 25686680 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25686680 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25686680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25686680 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 15043176 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1402218 — Surrogate Endpoint (SUR): Blood pressure
Study 6359885 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31234665 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 29540213 — Surrogate Endpoint (SUR): Blood pressure
Study 9705020 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9705020 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3383985 — Surrogate Endpoint (SUR): Serum creatinine
Study 12057715 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 12028321 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 8739162 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7066163 — Surrogate Endpoint (SUR): Blood pressure
Study 30610210 — Safety Biomarker (SAF): Hyaluronic acid
Study 27496126 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 18160008 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9598705 — Surrogate Endpoint (SUR): Blood pressure
Study 2702966 — Surrogate Endpoint (SUR): Blood pressure
Study 25937255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3027604 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28028194 — Surrogate Endpoint (SUR): Serum uric acid
Study 27909139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27909139 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 27909139 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21751197 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study 29221945 — Surrogate Endpoint (SUR): Bone mineral density
Study 20199208 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 18312042 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 22695039 — Surrogate Endpoint (SUR): Blood pressure
Study 22695039 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22695039 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein