TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16188958 — Surrogate Endpoint (SUR): Blood pressure
Study 8865525 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8865525 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28604556 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10566652 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 10566652 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 10566652 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7676795 — Surrogate Endpoint (SUR): Blood pressure
Study 2178522 — Surrogate Endpoint (SUR): Serum potassium
Study 20001450 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16041270 — Surrogate Endpoint (SUR): Serum creatinine
Study 7725851 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7725851 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31759909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25194004 — Surrogate Endpoint (SUR): Bone mineral density
Study 23514842 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23514842 — Surrogate Endpoint (SUR): Blood pressure
Study 15157345 — Safety Biomarker (SAF): DRD2
Study 30228265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20921964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20921964 — Surrogate Endpoint (SUR): Blood pressure
Study 20921964 — Safety Biomarker (SAF): BDNF
Study 18691778 — Surrogate Endpoint (SUR): Serum potassium
Study 16522906 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9209728 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 29480399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28331306 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28331306 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28331306 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18351337 — Predictive Biomarker (PRD): Liver iron
Study 7942933 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7942933 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2976727 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22048987 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 30742245 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 28459407 — Monitoring Biomarker (MOI): Procalcitonin
Study 28459407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28459407 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20040554 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11673819 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7986152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7986152 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7986152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21945737 — Surrogate Endpoint (SUR): Serum creatinine
Study 14699020 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11704086 — Surrogate Endpoint (SUR): Blood pressure
Study 2218871 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 6157258 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17571966 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 10404794 — Surrogate Endpoint (SUR): Blood pressure
Study 26028346 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 26028346 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26028346 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29782435 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20598488 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 16386942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 1731544 — Surrogate Endpoint (SUR): Blood pressure
Study 22474202 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 9377073 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3853581 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3853581 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18388088 — Surrogate Endpoint (SUR): Blood pressure
Study 24814697 — Safety Biomarker (SAF): Reactive oxygen species
Study 18173844 — Surrogate Endpoint (SUR): Blood pressure
Study 3052168 — Surrogate Endpoint (SUR): Blood pressure
Study 22005052 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 22005052 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11255716 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 30032196 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30032196 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30032196 — Predictive Biomarker (PRD): Hormone receptor
Study 25921382 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30890109 — Surrogate Endpoint (SUR): Blood pressure
Study 16215305 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31660904 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 9258265 — Surrogate Endpoint (SUR): Bone mineral density
Study 28870095 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9583838 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 9583838 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21518046 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 21518046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10948073 — Surrogate Endpoint (SUR): Blood pressure
Study 22954510 — Predictive Biomarker (PRD): OPRK1 mRNA
Genes: OPRK1; OPRK
Study 22954510 — Predictive Biomarker (PRD): OPRD1 mRNA
Genes: OPRD1; OPRD
Study 18426893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7955906 — Surrogate Endpoint (SUR): Blood pressure
Study 3117236 — Surrogate Endpoint (SUR): Blood pressure
Study 19211665 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 19211665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19211665 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19211665 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3475201 — Surrogate Endpoint (SUR): Blood pressure
Study 30561509 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 2169833 — Surrogate Endpoint (SUR): Blood pressure
Study 24274342 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 31162810 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 31162810 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31162810 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19664895 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8181200 — Surrogate Endpoint (SUR): Serum sodium
Study 8181200 — Surrogate Endpoint (SUR): Blood pressure
Study 23216616 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 21315210 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12727580 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9367464 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30236824 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 12055417 — Surrogate Endpoint (SUR): Blood pressure
Study 31640705 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26959184 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 15616030 — Surrogate Endpoint (SUR): Blood pressure
Study 15616030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12611732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12611732 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9650124 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 3378856 — Surrogate Endpoint (SUR): Blood pressure
Study 24569031 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 20659185 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 17261891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9033699 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9033699 — Surrogate Endpoint (SUR): Blood pressure
Study 27181277 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10192755 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 30561610 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26103129 — Surrogate Endpoint (SUR): Blood pressure
Study 20236716 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20236716 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10923282 — Surrogate Endpoint (SUR): Blood pressure
Study 8828991 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8828991 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 1424207 — Predictive Biomarker (PRD): Hormone receptor
Study 4096058 — Surrogate Endpoint (SUR): Blood pressure
Study 30134289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24356594 — Surrogate Endpoint (SUR): Blood pressure
Study 20308973 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9649976 — Surrogate Endpoint (SUR): Blood pressure
Study 11895463 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2898400 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 31452382 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18729781 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9622147 — Surrogate Endpoint (SUR): Blood pressure
Study 24239201 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28885881 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 21764693 — Predictive Biomarker (PRD): SLC22A4 mRNA
Genes: SLC22A4; ETT; OCTN1; UT2H
Study 21764693 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21764693 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 21764693 — Surrogate Endpoint (SUR): Blood pressure
Study 1389931 — Surrogate Endpoint (SUR): Blood pressure
Study 14977778 — Surrogate Endpoint (SUR): Blood pressure
Study 8095558 — Surrogate Endpoint (SUR): Serum potassium
Study 24142756 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23311404 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 23311404 — Surrogate Endpoint (SUR): Serum calcium
Study 1447501 — Surrogate Endpoint (SUR): Bone mineral density
Study 10674014 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 30479202 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 17170385 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 10800819 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10800819 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3967459 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23478476 — Surrogate Endpoint (SUR): Blood pressure
Study 7701032 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7701032 — Surrogate Endpoint (SUR): Blood pressure
Study 28562168 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21584681 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 16009798 — Surrogate Endpoint (SUR): Blood pressure
Study 28735818 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28735818 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25236187 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 675848 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24145678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6364906 — Surrogate Endpoint (SUR): Serum potassium
Study 6364906 — Surrogate Endpoint (SUR): Blood pressure
Study 31262366 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 27943112 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27943112 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23624802 — Predictive Biomarker (PRD): ISG15 mRNA
Genes: ISG15; G1P2; UCRP
Study 23624802 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 23624802 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 23624802 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 23624802 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 23624802 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 23624802 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21285885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21285885 — Surrogate Endpoint (SUR): Serum creatinine
Study 21285885 — Surrogate Endpoint (SUR): Serum sodium
Study 19342599 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 19342599 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21574963 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 21574963 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25447615 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8221449 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 27400912 — Predictive Biomarker (PRD): ZNF423 mRNA
Genes: ZNF423; KIAA0760; NPHP14; OAZ
Study 27400912 — Predictive Biomarker (PRD): CTSO mRNA
Genes: CTSO; CTSO1
Study 24938224 — Surrogate Endpoint (SUR): Blood pressure
Study 12766124 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25378913 — Surrogate Endpoint (SUR): Blood pressure
Study 20658791 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26846607 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26846607 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22583135 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16101620 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 11908467 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21266057 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 21266057 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 21266057 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 14624410 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14624410 — Surrogate Endpoint (SUR): Blood pressure
Study 14624410 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14624410 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12127381 — Surrogate Endpoint (SUR): Blood pressure
Study 10447791 — Surrogate Endpoint (SUR): Blood pressure
Study 7594703 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 367885 — Surrogate Endpoint (SUR): Serum uric acid
Study 367885 — Surrogate Endpoint (SUR): Serum creatinine
Study 19769721 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30041526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30041526 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 30041526 — Safety Biomarker (SAF): Interleukin 1
Study 21907863 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29909907 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20930337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26898348 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12370800 — Surrogate Endpoint (SUR): Bone mineral density
Study 2655606 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23523573 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 21511841 — Surrogate Endpoint (SUR): Blood pressure
Study 21511841 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14501605 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14501605 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 3553479 — Surrogate Endpoint (SUR): Blood pressure
Study 28320895 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26154928 — Surrogate Endpoint (SUR): Serum creatinine
Study 24299565 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 9272232 — Surrogate Endpoint (SUR): Sperm parameters
Study 27151177 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27151177 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25190434 — Monitoring Biomarker (MOI): HBV DNA
Study 22192866 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 16848911 — Surrogate Endpoint (SUR): Blood pressure
Study 9248871 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 23989106 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23989106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22805400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22805400 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11722966 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31454802 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 31454802 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1952202 — Surrogate Endpoint (SUR): Blood pressure
Study 21685813 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 19261927 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 17477865 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 12791021 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8473790 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2655822 — Surrogate Endpoint (SUR): Serum creatinine
Study 2655822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27537410 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 27537410 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19865538 — Predictive Biomarker (PRD): PON2 mRNA
Genes: PON2
Study 15070924 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9677791 — Predictive Biomarker (PRD): MMP12 mRNA
Genes: MMP12; HME
Study 8131528 — Surrogate Endpoint (SUR): Blood pressure
Study 8131528 — Surrogate Endpoint (SUR): Serum potassium
Study 8131528 — Surrogate Endpoint (SUR): Serum calcium
Study 31237547 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28192584 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25490004 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7961547 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 17295900 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17295900 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 23179200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23179200 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 23179200 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23179200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23179200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12531794 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 12531794 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10812254 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8214043 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 16150805 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7608448 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30608989 — Predictive Biomarker (PRD): CADM1 mRNA
Genes: CADM1; IGSF4; IGSF4A; NECL2; SYNCAM; TSLC1
Study 30608989 — Predictive Biomarker (PRD): TAFA4 mRNA
Genes: TAFA4; FAM19A4
Study 30608989 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 17045894 — Surrogate Endpoint (SUR): Blood pressure
Study 12740675 — Safety Biomarker (SAF): Hyaluronic acid
Study 31775146 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 31775146 — Predictive Biomarker (PRD): DTL mRNA
Genes: DTL; CDT2; CDW1; DCAF2; L2DTL; RAMP
Study 18474395 — Surrogate Endpoint (SUR): Blood pressure