TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20737243 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 20737243 — Predictive Biomarker (PRD): TFRC mRNA
Genes: TFRC
Study 11710825 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7964949 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 18020004 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25854019 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21148662 — Surrogate Endpoint (SUR): Blood pressure
Study 22323575 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20226430 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15580479 — Surrogate Endpoint (SUR): Bone mineral density
Study 15312253 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15312253 — Surrogate Endpoint (SUR): Serum testosterone
Study 16340629 — Surrogate Endpoint (SUR): Blood pressure
Study 16340629 — Surrogate Endpoint (SUR): Serum creatinine
Study 14550800 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 6389909 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 14620302 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 28301435 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16750207 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18795367 — Surrogate Endpoint (SUR): Blood pressure
Study 18795367 — Safety Biomarker (SAF): Urinary microalbumin
Study 16918520 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 2446055 — Surrogate Endpoint (SUR): Blood pressure
Study 19755414 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19755414 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23590986 — Surrogate Endpoint (SUR): Pathological complete response
Study 21664512 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 12700448 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11121720 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31349945 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31349945 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 31349945 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 31349945 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31349945 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31349945 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28096757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28096757 — Surrogate Endpoint (SUR): Blood pressure
Study 16797309 — Surrogate Endpoint (SUR): Serum creatinine
Study 12587810 — Surrogate Endpoint (SUR): Blood pressure
Study 21675122 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 21675122 — Predictive Biomarker (PRD): BLOC1S2 mRNA
Genes: BLOC1S2; BLOS2; CEAP
Study 21675122 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 21675122 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21675122 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31742881 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 31742881 — Surrogate Endpoint (SUR): Serum uric acid
Study 31742881 — Surrogate Endpoint (SUR): Blood pressure
Study 25771851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25771851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25771851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25771851 — Safety Biomarker (SAF): Interleukin 1
Study 31978225 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 31978225 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 31978225 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16931264 — Surrogate Endpoint (SUR): Blood pressure
Study 12601528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30872737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24577471 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 17110604 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17110604 — Predictive Biomarker (PRD): CPT1A mRNA
Genes: CPT1A; CPT1
Study 17110604 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 17110604 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 17110604 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17110604 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor delta
Genes: PPARD
Study 27322311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21542114 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 30782715 — Surrogate Endpoint (SUR): Blood pressure
Study 20828790 — Surrogate Endpoint (SUR): Blood pressure
Study 11427833 — Surrogate Endpoint (SUR): Blood pressure
Study 28291587 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 27168265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9592991 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 7512433 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18267006 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17087052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17087052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25864872 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21801494 — Predictive Biomarker (PRD): XDH mRNA
Genes: XDH; XDHA
Study 21801494 — Safety Biomarker (SAF): Reactive oxygen species
Study 7706699 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31365829 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 24740462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24740462 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study 18501499 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study 18501499 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 31880966 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11513193 — Safety Biomarker (SAF): Interleukin 12
Study 9640077 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 26948991 — Surrogate Endpoint (SUR): Blood pressure
Study 24357575 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 21899712 — Surrogate Endpoint (SUR): Pathological complete response
Study 23782513 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16476843 — Surrogate Endpoint (SUR): Blood pressure
Study 8603558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1419473 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1419473 — Surrogate Endpoint (SUR): Blood pressure
Study 29716756 — Predictive Biomarker (PRD): RRS1 mRNA
Genes: RRS1; KIAA0112; RRR
Study 23227677 — Surrogate Endpoint (SUR): Blood pressure
Study 20722847 — Surrogate Endpoint (SUR): Bone mineral density
Study 18388249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7580706 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2068533 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9679794 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7983283 — Surrogate Endpoint (SUR): Serum sodium
Study 26919735 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3812270 — Surrogate Endpoint (SUR): Blood pressure
Study 25675113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 25675113 — Predictive Biomarker (PRD): let-7b
Genes: MIRLET7B
Study 23616512 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23616512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23616512 — Surrogate Endpoint (SUR): Blood pressure
Study 19001792 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17283875 — Surrogate Endpoint (SUR): Blood pressure
Study 28332096 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 26133996 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26133996 — Surrogate Endpoint (SUR): Blood pressure
Study 18165577 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 16096330 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 31216065 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 22448235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18025896 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15159722 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1972207 — Surrogate Endpoint (SUR): Blood pressure
Study 22097200 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 22097200 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22097200 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 22097200 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 14659974 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7951099 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7526067 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7526067 — Surrogate Endpoint (SUR): Blood pressure
Study 26754182 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24943987 — Surrogate Endpoint (SUR): Blood pressure
Study 23286297 — Predictive Biomarker (PRD): KIF22 mRNA
Genes: KIF22; KID; KNSL4
Study 17976963 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 17976963 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 15871443 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31444999 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31444999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31444999 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31444999 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26924549 — Safety Biomarker (SAF): Hyaluronic acid
Study 22424025 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22424025 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17499999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17499999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30946156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17315084 — Surrogate Endpoint (SUR): Bone mineral density
Study 15038622 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15038622 — Surrogate Endpoint (SUR): Blood pressure
Study 7837014 — Safety Biomarker (SAF): Hyaluronic acid
Study 3414406 — Surrogate Endpoint (SUR): Blood pressure
Study 31922432 — Surrogate Endpoint (SUR): Blood pressure
Study 28611110 — Surrogate Endpoint (SUR): Bone mineral density
Study 23374898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23374898 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23374898 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23374898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23374898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16390499 — Surrogate Endpoint (SUR): Serum testosterone
Study 16390499 — Surrogate Endpoint (SUR): Bone mineral density
Study 10929446 — Surrogate Endpoint (SUR): Bone mineral density
Study 4003919 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20537455 — Surrogate Endpoint (SUR): Serum creatinine
Study 20537455 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 29446445 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24465425 — Surrogate Endpoint (SUR): Blood pressure
Study 24465425 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24465425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24465425 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10624546 — Safety Biomarker (SAF): Interleukin 1
Study 30156056 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31495201 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17338766 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 28972192 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 15024666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17693902 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17693902 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17297830 — Surrogate Endpoint (SUR): Blood pressure
Study 12941060 — Surrogate Endpoint (SUR): Blood pressure
Study 9199606 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 2580177 — Surrogate Endpoint (SUR): Blood pressure
Study 2580177 — Surrogate Endpoint (SUR): Serum potassium
Study 30382485 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 29879277 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 26927908 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 26927908 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 25326008 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19458624 — Surrogate Endpoint (SUR): Blood pressure
Study 15831604 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14601488 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 14601488 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 14601488 — Predictive Biomarker (PRD): GCSAM mRNA
Genes: GCSAM; GAL; GCET2
Study 6784917 — Predictive Biomarker (PRD): TIMM8A mRNA
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 6784917 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 26559501 — Surrogate Endpoint (SUR): Blood pressure
Study 10714911 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 10714911 — Surrogate Endpoint (SUR): Bone mineral density
Study 9468004 — Surrogate Endpoint (SUR): Blood pressure
Study 23932548 — Predictive Biomarker (PRD): Hormone receptor
Study 15597521 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11374699 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 1512689 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1512689 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 1512689 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31283835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31689007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31689007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10898413 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 8817407 — Surrogate Endpoint (SUR): Blood pressure
Study 1422288 — Surrogate Endpoint (SUR): Blood pressure
Study 4059722 — Surrogate Endpoint (SUR): Blood pressure
Study 2897305 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2897305 — Surrogate Endpoint (SUR): Blood pressure
Study 23020859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23020859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23020859 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15937908 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2547411 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15112887 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7946161 — Surrogate Endpoint (SUR): Blood pressure
Study 25653155 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 25653155 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21118844 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21118844 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 12907532 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 12907532 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 30222842 — Predictive Biomarker (PRD): TPSG1 mRNA
Genes: TPSG1; PRSS31; TMT
Study 19889524 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19889524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11854116 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 28874142 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 28874142 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30562322 — Surrogate Endpoint (SUR): Blood pressure
Study 10355512 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 10355512 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 8952741 — Surrogate Endpoint (SUR): Blood pressure
Study 20048489 — Safety Biomarker (SAF): Hyaluronic acid
Study 2949910 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30503129 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 30503129 — Predictive Biomarker (PRD): BMPR1B mRNA
Genes: BMPR1B
Study 7572748 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2145237 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30770294 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 25516371 — Surrogate Endpoint (SUR): Blood pressure
Study 17203292 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15213052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2686489 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2686489 — Surrogate Endpoint (SUR): Blood pressure
Study 20519561 — Surrogate Endpoint (SUR): Blood pressure
Study 18075766 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 22443173 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 8955760 — Surrogate Endpoint (SUR): Serum creatinine
Study 8955760 — Surrogate Endpoint (SUR): Blood pressure
Study 25114912 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 25114912 — Surrogate Endpoint (SUR): Blood pressure
Study 19478822 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 31833064 — Surrogate Endpoint (SUR): Blood pressure
Study 21429214 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 21429214 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2567113 — Surrogate Endpoint (SUR): Blood pressure
Study 2567113 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31148411 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 31148411 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26169561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21352267 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19701575 — Surrogate Endpoint (SUR): Blood pressure
Study 9134282 — Surrogate Endpoint (SUR): Blood pressure
Study 395959 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 24950276 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21775749 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 21775749 — Surrogate Endpoint (SUR): Blood pressure
Study 21775749 — Surrogate Endpoint (SUR): Serum creatinine
Study 17091022 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15303639 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15303639 — Surrogate Endpoint (SUR): Blood pressure
Study 3305189 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 3305189 — Predictive Biomarker (PRD): SH2D2A mRNA
Genes: SH2D2A; SCAP; TSAD; VRAP
Study 12633783 — Surrogate Endpoint (SUR): Bone mineral density
Study 10686191 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 19363850 — Surrogate Endpoint (SUR): Blood pressure
Study 8953207 — Surrogate Endpoint (SUR): Blood pressure
Study 19228095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15013031 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 7950223 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28634365 — Surrogate Endpoint (SUR): Blood pressure
Study 18476292 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20382711 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor