TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7815748 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2576666 — Surrogate Endpoint (SUR): Blood pressure
Study 23788085 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 15333056 — Surrogate Endpoint (SUR): Blood pressure
Study 8670601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1662583 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31912800 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 31912800 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 14984149 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 14728013 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14728013 — Surrogate Endpoint (SUR): Blood pressure
Study 3119959 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 3119959 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2869057 — Surrogate Endpoint (SUR): Blood pressure
Study 22117974 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2691819 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2691819 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 2691819 — Surrogate Endpoint (SUR): Blood pressure
Study 4581080 — Surrogate Endpoint (SUR): Blood pressure
Study 30586365 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 30586365 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 27586506 — Surrogate Endpoint (SUR): Serum testosterone
Study 27586506 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 27586506 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 19025397 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 19025397 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study 19025397 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19025397 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 25746819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10216104 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 10216104 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12920491 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12920491 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 12920491 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 3701184 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24309381 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 15693916 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7672685 — Surrogate Endpoint (SUR): Bone mineral density
Study 31563397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31399108 — Predictive Biomarker (PRD): NOX4 mRNA
Genes: NOX4; RENOX
Study 31399108 — Safety Biomarker (SAF): Reactive oxygen species
Study 17436778 — Surrogate Endpoint (SUR): Blood pressure
Study 17436778 — Surrogate Endpoint (SUR): Serum creatinine
Study 9496204 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9496204 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7934984 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24991038 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 10862645 — Surrogate Endpoint (SUR): Serum creatinine
Study 10862645 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9357886 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 15001601 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10546469 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7075639 — Surrogate Endpoint (SUR): Blood pressure
Study 31876118 — Safety Biomarker (SAF): Hyaluronic acid
Study 26909743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23379240 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20702792 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16242948 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11855542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11855542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22648712 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 16318978 — Predictive Biomarker (PRD): PIBF1 mRNA
Genes: PIBF1; C13orf24; PIBF
Study 12629248 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12569789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12569789 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1992214 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1992214 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29656442 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 29656442 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29656442 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 17613258 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 6154200 — Surrogate Endpoint (SUR): Blood pressure
Study 28389510 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 24518789 — Surrogate Endpoint (SUR): Serum uric acid
Study 11606148 — Surrogate Endpoint (SUR): Bone mineral density
Study 2189430 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1106218 — Surrogate Endpoint (SUR): Blood pressure
Study 27935076 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 19273450 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 19273450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16893569 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11397886 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17943257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12787302 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 12787302 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12787302 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 12787302 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12787302 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8723581 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30814213 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 25223378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22906144 — Surrogate Endpoint (SUR): Blood pressure
Study 17430101 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8879780 — Surrogate Endpoint (SUR): Serum creatinine
Study 29664714 — Predictive Biomarker (PRD): Hormone receptor
Study 29664714 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24029392 — Predictive Biomarker (PRD): PHC1 mRNA
Genes: PHC1; EDR1; PH1
Study 23126349 — Surrogate Endpoint (SUR): Blood pressure
Study 26631058 — Surrogate Endpoint (SUR): Blood pressure
Study 26631058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23769265 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 17204832 — Surrogate Endpoint (SUR): Blood pressure
Study 27903997 — Surrogate Endpoint (SUR): Serum calcium
Study 27903997 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27903997 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24738695 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24738695 — Safety Biomarker (SAF): Reactive oxygen species
Study 23744760 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19488866 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 19488866 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 19488866 — Predictive Biomarker (PRD): AFF1 mRNA
Genes: AFF1; AF4; FEL; MLLT2; PBM1
Study 19488866 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 19488866 — Predictive Biomarker (PRD): TCF3 mRNA
Genes: TCF3; BHLHB21; E2A; ITF1
Study 19488866 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 18378744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18378744 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18378744 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18378744 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28875955 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 28875955 — Monitoring Biomarker (MOI): HBV DNA
Study 22912450 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 17456679 — Surrogate Endpoint (SUR): Blood pressure
Study 11922396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 8275216 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8275216 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2880603 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2880603 — Surrogate Endpoint (SUR): Blood pressure
Study 30647072 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19842559 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19842559 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15132723 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15132723 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11532054 — Surrogate Endpoint (SUR): Blood pressure
Study 20146063 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18490077 — Monitoring Biomarker (MOI): HBV DNA
Study 9517592 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 2488113 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31169558 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 31169558 — Predictive Biomarker (PRD): MAGI1 mRNA
Genes: MAGI1; AIP3; BAIAP1; BAP1; TNRC19
Study 31169558 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 19567926 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16877955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21512411 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15311720 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15311720 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2946313 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21272319 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 21272319 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 21272319 — Predictive Biomarker (PRD): AZGP1 mRNA
Genes: AZGP1; ZAG; ZNGP1
Study 14628279 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9714028 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 31515250 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study 15010034 — Surrogate Endpoint (SUR): Bone mineral density
Study 10653925 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25032713 — Surrogate Endpoint (SUR): Serum creatinine
Study 19243818 — Safety Biomarker (SAF): Interleukin 12
Study 20414637 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 20414637 — Surrogate Endpoint (SUR): Blood pressure
Study 18373403 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 18373403 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 9344829 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 25842469 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 20073139 — Surrogate Endpoint (SUR): Blood pressure
Study 15562054 — Surrogate Endpoint (SUR): Blood pressure
Study 29142036 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 22913981 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20133267 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16710356 — Surrogate Endpoint (SUR): Blood pressure
Study 22808020 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21135327 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17952581 — Surrogate Endpoint (SUR): Serum creatinine
Study 6138116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11219482 — Surrogate Endpoint (SUR): Blood pressure
Study 2697728 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2697728 — Surrogate Endpoint (SUR): Blood pressure
Study 16856900 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11127214 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 11127214 — Surrogate Endpoint (SUR): Bone mineral density
Study 11127214 — Surrogate Endpoint (SUR): Serum calcium
Study 30106956 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 22986466 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22986466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22700888 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22700888 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20683945 — Monitoring Biomarker (MOI): HBV DNA
Study 19858400 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22918177 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 10469713 — Surrogate Endpoint (SUR): Bone mineral density
Study 25296241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23217889 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 8546884 — Surrogate Endpoint (SUR): Blood pressure
Study 23227139 — Predictive Biomarker (PRD): SYNM mRNA
Genes: SYNM; DMN; KIAA0353; SYN
Study 19577757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19577757 — Surrogate Endpoint (SUR): Blood pressure
Study 10232626 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 6419419 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 29089455 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 26527775 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26527775 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 26527775 — Predictive Biomarker (PRD): Hormone receptor
Study 19960973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19960973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15077102 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15077102 — Surrogate Endpoint (SUR): Blood pressure
Study 7522018 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22818224 — Surrogate Endpoint (SUR): Blood pressure
Study 22011457 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15954968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15954968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7795987 — Surrogate Endpoint (SUR): Blood pressure
Study 27895044 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study 27895044 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 27895044 — Predictive Biomarker (PRD): GNAQ mRNA
Genes: GNAQ; GAQ
Study 16208088 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7768079 — Surrogate Endpoint (SUR): Blood pressure
Study 20715733 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29633507 — Surrogate Endpoint (SUR): Plasma testosterone level
Study 24316088 — Predictive Biomarker (PRD): PRF1
Genes: PFP; P1; HPLH2
Study 1887821 — Surrogate Endpoint (SUR): Bone mineral density
Study 31601239 — Surrogate Endpoint (SUR): Blood pressure
Study 24491874 — Surrogate Endpoint (SUR): Blood pressure
Study 20970650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 16844623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16844623 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 12925471 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1799190 — Surrogate Endpoint (SUR): Serum creatinine
Study 24910270 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19828909 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 11900495 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 2330930 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25652873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25652873 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 21454745 — Surrogate Endpoint (SUR): Blood pressure
Study 7702060 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7702060 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21653990 — Surrogate Endpoint (SUR): Blood pressure
Study 19342867 — Surrogate Endpoint (SUR): Blood pressure
Study 16188495 — Surrogate Endpoint (SUR): Blood pressure
Study 16188495 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10687746 — Surrogate Endpoint (SUR): Blood pressure
Study 25496514 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 18712038 — Surrogate Endpoint (SUR): Blood pressure
Study 18712038 — Surrogate Endpoint (SUR): Serum creatinine
Study 18712038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10477009 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10477009 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10477009 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 30312423 — Surrogate Endpoint (SUR): Bone mineral density
Study 28315479 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 1745709 — Surrogate Endpoint (SUR): Blood pressure
Study 22832261 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18989229 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12117739 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12117739 — Surrogate Endpoint (SUR): Blood pressure
Study 12117739 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12117739 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12117739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12117739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19195498 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19195498 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12958326 — Surrogate Endpoint (SUR): Blood pressure
Study 31898965 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30501618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15571210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15571210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15571210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11731753 — Surrogate Endpoint (SUR): Blood pressure
Study 27496680 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20808331 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14551179 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 14551179 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 14551179 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8695243 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8695243 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 8695243 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 1839981 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 20200939 — Surrogate Endpoint (SUR): Bone mineral density
Study 15674304 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15674304 — Surrogate Endpoint (SUR): Blood pressure
Study 21054554 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15146102 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11593317 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26377342 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21736934 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 12900588 — Surrogate Endpoint (SUR): Blood pressure
Study 9371668 — Surrogate Endpoint (SUR): Serum creatinine
Study 2006660 — Surrogate Endpoint (SUR): Serum creatinine
Study 22385260 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA