TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9894538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28108978 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 31182338 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19443520 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15197140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15197140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8064994 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31498370 — Surrogate Endpoint (SUR): Blood pressure
Study 23288297 — Surrogate Endpoint (SUR): Blood pressure
Study 20096957 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 16618360 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 26927662 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26927662 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24360369 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 12061359 — Surrogate Endpoint (SUR): Serum sodium
Study 25124510 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21479698 — Predictive Biomarker (PRD): KIR2DL4 mRNA
Genes: KIR2DL4; CD158D; KIR103AS
Study 19166627 — Surrogate Endpoint (SUR): Blood pressure
Study 17244451 — Monitoring Biomarker (MOI): HBV DNA
Study 22492369 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22492369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11943558 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24220287 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17264176 — Surrogate Endpoint (SUR): Bone mineral density
Study 3987783 — Surrogate Endpoint (SUR): Blood pressure
Study 3987783 — Surrogate Endpoint (SUR): Serum potassium
Study 20413516 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3937154 — Surrogate Endpoint (SUR): Blood pressure
Study 28705551 — Surrogate Endpoint (SUR): Blood pressure
Study 17180572 — Surrogate Endpoint (SUR): Serum creatinine
Study 31972655 — Surrogate Endpoint (SUR): Blood pressure
Study 18982782 — Surrogate Endpoint (SUR): Blood pressure
Study 1693711 — Surrogate Endpoint (SUR): Blood pressure
Study 29072977 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9118690 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 9118690 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9118690 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 8441570 — Surrogate Endpoint (SUR): Blood pressure
Study 2876183 — Surrogate Endpoint (SUR): Blood pressure
Study 31789965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30413407 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 22984204 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 11111188 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11111188 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11132613 — Surrogate Endpoint (SUR): Blood pressure
Study 2859054 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 19289389 — Surrogate Endpoint (SUR): Blood pressure
Study 19289389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15190963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15190963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15190963 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15190963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11477830 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11477830 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31534062 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23361468 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 2690971 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16896957 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 16896957 — Safety Biomarker (SAF): DRD2
Study 15333468 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 15333468 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 11393383 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11393383 — Safety Biomarker (SAF): 51Cr-EDTA
Study 11393383 — Surrogate Endpoint (SUR): Blood pressure
Study 2565917 — Surrogate Endpoint (SUR): Blood pressure
Study 332217 — Surrogate Endpoint (SUR): Blood pressure
Study 28941934 — Surrogate Endpoint (SUR): Blood pressure
Study 26467594 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 19491535 — Surrogate Endpoint (SUR): Blood pressure
Study 9247840 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 22718380 — Surrogate Endpoint (SUR): Blood pressure
Study 15470214 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11406729 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24799467 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19284395 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 802922 — Surrogate Endpoint (SUR): Serum potassium
Study 28591155 — Surrogate Endpoint (SUR): Blood pressure
Study 25957214 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24166282 — Predictive Biomarker (PRD): Hormone receptor
Study 17544776 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9734615 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 3335145 — Surrogate Endpoint (SUR): Blood pressure
Study 31564843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18284437 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22206777 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 1854763 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31440862 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27460541 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 27460541 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 10367037 — Surrogate Endpoint (SUR): Bone mineral density
Study 2165088 — Surrogate Endpoint (SUR): Blood pressure
Study 21843222 — Surrogate Endpoint (SUR): Blood pressure
Study 15289492 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12451007 — Surrogate Endpoint (SUR): Blood pressure
Study 9720812 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 9720812 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 7705114 — Surrogate Endpoint (SUR): Forced vital capacity
Study 566734 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29460262 — Surrogate Endpoint (SUR): Blood pressure
Study 19331437 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19331437 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19331437 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19331437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17709798 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 17709798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27250495 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 3417466 — Surrogate Endpoint (SUR): Blood pressure
Study 27914033 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25782065 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17413095 — Surrogate Endpoint (SUR): Bone mineral density
Study 12577419 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 9701408 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 31897483 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 30098917 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24595577 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 24595577 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24595577 — Predictive Biomarker (PRD): OGG1 mRNA
Genes: OGG1; MMH; MUTM; OGH1
Study 9767368 — Surrogate Endpoint (SUR): Blood pressure
Study 8121439 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10516740 — Surrogate Endpoint (SUR): Blood pressure
Study 24417772 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10828010 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 2000050 — Surrogate Endpoint (SUR): Blood pressure
Study 29078915 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 19180072 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 8580276 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8580276 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30356327 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 30356327 — Surrogate Endpoint (SUR): Serum uric acid
Study 30356327 — Surrogate Endpoint (SUR): Serum calcium
Study 30356327 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24947928 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11575540 — Surrogate Endpoint (SUR): Blood pressure
Study 21690555 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 21690555 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 15245344 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27715351 — Surrogate Endpoint (SUR): Blood pressure
Study 27715351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29793828 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 29793828 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19690659 — Surrogate Endpoint (SUR): Bone mineral density
Study 11575417 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22563189 — Safety Biomarker (SAF): Hyaluronic acid
Study 28392859 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17535634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11277584 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 8056008 — Surrogate Endpoint (SUR): Blood pressure
Study 15128184 — Predictive Biomarker (PRD): LST1 mRNA
Genes: LST1; B144
Study 15128184 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 15128184 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 25870325 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25870325 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23467207 — Surrogate Endpoint (SUR): Blood pressure
Study 21502796 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 17870038 — Surrogate Endpoint (SUR): Bone mineral density
Study 11078484 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 9681390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21709297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16369811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12771456 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31438901 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 27450228 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 25419180 — Monitoring Biomarker (MOI): Procalcitonin
Study 25419180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8899469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8899469 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 25602290 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 24737459 — Surrogate Endpoint (SUR): Blood pressure
Study 19254366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10749962 — Surrogate Endpoint (SUR): Blood pressure
Study 10749962 — Surrogate Endpoint (SUR): Serum creatinine
Study 10749962 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22955035 — Surrogate Endpoint (SUR): Blood pressure
Study 8524760 — Predictive Biomarker (PRD): EHF mRNA
Genes: EHF; ESE3; ESE3B; ESEJ
Study 1957647 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 31419219 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28153946 — Surrogate Endpoint (SUR): Blood pressure
Study 26172895 — Surrogate Endpoint (SUR): Serum potassium
Study 11744142 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11744142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11744142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9468005 — Surrogate Endpoint (SUR): Blood pressure
Study 2455111 — Surrogate Endpoint (SUR): Blood pressure
Study 27406346 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24927078 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24927078 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26848148 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 26848148 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 12711469 — Predictive Biomarker (PRD): CYP2S1 mRNA
Genes: CYP2S1; UNQ891/PRO1906
Study 12711469 — Predictive Biomarker (PRD): CYP26A1 mRNA
Genes: CYP26A1; CYP26; P450RAI1
Study 30272388 — Surrogate Endpoint (SUR): Blood pressure
Study 12093068 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 6372981 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29807091 — Monitoring Biomarker (MOI): Procalcitonin
Study 29807091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17483363 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 25600905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23664333 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8874988 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31337003 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27350174 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 27350174 — Surrogate Endpoint (SUR): Serum potassium
Study 27350174 — Surrogate Endpoint (SUR): Blood pressure
Study 19924121 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 19924121 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23601443 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 23601443 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16766979 — Surrogate Endpoint (SUR): Blood pressure
Study 11122893 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 2439826 — Surrogate Endpoint (SUR): Blood pressure
Study 3288140 — Surrogate Endpoint (SUR): Blood pressure
Study 21792013 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 21792013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18996761 — Surrogate Endpoint (SUR): Serum calcium
Study 18996761 — Surrogate Endpoint (SUR): Bone mineral density
Study 9085957 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9085957 — Surrogate Endpoint (SUR): Blood pressure
Study 3947233 — Surrogate Endpoint (SUR): Serum creatinine
Study 18834373 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 7701173 — Surrogate Endpoint (SUR): Blood pressure
Study 2272007 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26682793 — Surrogate Endpoint (SUR): Blood pressure
Study 26682793 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22218164 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 7986410 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7986410 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28871621 — Surrogate Endpoint (SUR): Blood pressure
Study 28871621 — Surrogate Endpoint (SUR): Serum creatinine
Study 23589326 — Surrogate Endpoint (SUR): Blood pressure
Study 19331489 — Predictive Biomarker (PRD): GRIK1 mRNA
Genes: GRIK1; GLUR5
Study 8039154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2553568 — Surrogate Endpoint (SUR): Blood pressure
Study 18568687 — Surrogate Endpoint (SUR): Blood pressure
Study 14685863 — Safety Biomarker (SAF): Reactive oxygen species
Study 14685863 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3106095 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3106095 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26894413 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26894413 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26894413 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15810908 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15810908 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 8848333 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8848333 — Surrogate Endpoint (SUR): Blood pressure
Study 1510256 — Surrogate Endpoint (SUR): Blood pressure
Study 19240707 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 19240707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19240707 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19240707 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19240707 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 19240707 — Safety Biomarker (SAF): Interleukin 1
Study 19240707 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8200333 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 7225166 — Surrogate Endpoint (SUR): Serum creatinine
Study 21366944 — Surrogate Endpoint (SUR): Blood pressure
Study 30625398 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30625398 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10476895 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 8945694 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30272851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30272851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16303697 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2194314 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2194314 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2194314 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 692548 — Surrogate Endpoint (SUR): Blood pressure
Study 24103211 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24103211 — Safety Biomarker (SAF): BDNF
Study 20688744 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 12949718 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 12949718 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 22085203 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20001392 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20001392 — Surrogate Endpoint (SUR): Blood pressure
Study 12796368 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 12796368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12796368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29175417 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29175417 — Predictive Biomarker (PRD): ESRRB mRNA
Genes: ESRRB; ERRB2; ESRL2; NR3B2
Study 28902534 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24395447 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24395447 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20109118 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20109118 — Surrogate Endpoint (SUR): Blood pressure
Study 20109118 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12013158 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30932775 — Surrogate Endpoint (SUR): Blood pressure
Study 30203770 — Surrogate Endpoint (SUR): Blood pressure