TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17654322 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10442597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10442597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10027431 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8643170 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2298365 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 27762041 — Surrogate Endpoint (SUR): Blood pressure
Study 20167989 — Surrogate Endpoint (SUR): Blood pressure
Study 1632567 — Surrogate Endpoint (SUR): Blood pressure
Study 6436700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22395644 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17109580 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15193361 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study 15193361 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 28366818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28366818 — Surrogate Endpoint (SUR): Probing pocket depth
Study 28422526 — Surrogate Endpoint (SUR): Serum creatinine
Study 23038021 — Surrogate Endpoint (SUR): Blood pressure
Study 15569335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 3723621 — Surrogate Endpoint (SUR): Blood pressure
Study 24719474 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22699098 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20207324 — Surrogate Endpoint (SUR): Blood pressure
Study 12592683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12592683 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10379638 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9295496 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1870835 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25827448 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23063141 — Surrogate Endpoint (SUR): Blood pressure
Study 10446825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21044101 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 2205624 — Surrogate Endpoint (SUR): Bone mineral density
Study 2205624 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2205624 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2205624 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27137171 — Predictive Biomarker (PRD): FBL mRNA
Genes: FBL; FIB1; FLRN
Study 21593280 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 14525823 — Surrogate Endpoint (SUR): Blood pressure
Study 11097156 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 11097156 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11097156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26678391 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 18436116 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 10789600 — Surrogate Endpoint (SUR): Blood pressure
Study 3170995 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20100966 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16019088 — Surrogate Endpoint (SUR): Blood pressure
Study 1391670 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 1391670 — Predictive Biomarker (PRD): KIAA1217 mRNA
Genes: KIAA1217; SKT
Study 9419612 — Surrogate Endpoint (SUR): Blood pressure
Study 18036357 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18036357 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18036357 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18036357 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 2097716 — Surrogate Endpoint (SUR): Serum creatinine
Study 2097716 — Safety Biomarker (SAF): 51Cr-EDTA
Study 421548 — Surrogate Endpoint (SUR): Blood pressure
Study 17983369 — Monitoring Biomarker (MOI): HBV DNA
Study 11581544 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 31813637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26643116 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 8860713 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10519449 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7500507 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30715997 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 186089 — Surrogate Endpoint (SUR): Blood pressure
Study 22185349 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10910008 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10910008 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9048788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9048788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23430442 — Predictive Biomarker (PRD): SNAI2 mRNA
Genes: SNAI2; SLUG; SLUGH
Study 9488244 — Surrogate Endpoint (SUR): Blood pressure
Study 30158160 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 20420759 — Surrogate Endpoint (SUR): Blood pressure
Study 11115412 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9117878 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2954222 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 31846974 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 27935537 — Surrogate Endpoint (SUR): Blood pressure
Study 22197120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18234392 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study 17165277 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8896952 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 24863949 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18418965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14606705 — Monitoring Biomarker (MOI): HBV DNA
Study 10772202 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30021449 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25175787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25175787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2510959 — Surrogate Endpoint (SUR): Serum creatinine
Study 52896 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 22893251 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 22893251 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 22893251 — Safety Biomarker (SAF): DRD2
Study 31159805 — Surrogate Endpoint (SUR): Blood pressure
Study 28155057 — Surrogate Endpoint (SUR): Blood pressure
Study 8346498 — Safety Biomarker (SAF): 51Cr-EDTA
Study 23913968 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 11110232 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15965585 — Predictive Biomarker (PRD): RNPEP mRNA
Genes: RNPEP; APB
Study 30075763 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 20337955 — Surrogate Endpoint (SUR): Blood pressure
Study 18380946 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 28735851 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23564564 — Predictive Biomarker (PRD): MTA1 mRNA
Genes: MTA1
Study 22055259 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17940996 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 15086935 — Surrogate Endpoint (SUR): Serum calcium
Study 1586711 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28319997 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28319997 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 15067204 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15067204 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15067204 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 15067204 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15067204 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 15067204 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15067204 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9663811 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9663811 — Surrogate Endpoint (SUR): Blood pressure
Study 24229676 — Surrogate Endpoint (SUR): Blood pressure
Study 26414968 — Surrogate Endpoint (SUR): Blood pressure
Study 26414968 — Surrogate Endpoint (SUR): Serum potassium
Study 24067210 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 20864558 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 7562112 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7562112 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24498939 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 2036817 — Surrogate Endpoint (SUR): Serum potassium
Study 29072020 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26679702 — Surrogate Endpoint (SUR): Blood pressure
Study 26679702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23926585 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18541517 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 10892946 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 8725891 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1920343 — Surrogate Endpoint (SUR): Blood pressure
Study 26958746 — Surrogate Endpoint (SUR): Serum sodium
Study 22383748 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22383748 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 14990551 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 12235451 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9521221 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11079287 — Surrogate Endpoint (SUR): Blood pressure
Study 24857719 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 11185675 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 22154198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22154198 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10711607 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 7967324 — Surrogate Endpoint (SUR): Blood pressure
Study 27449221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22379070 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 18427362 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31215755 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 22676966 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22676966 — Safety Biomarker (SAF): BDNF
Study 9343284 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8404931 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25829397 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25829397 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 23109243 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21530339 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 21530339 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 18975369 — Surrogate Endpoint (SUR): Serum creatinine
Study 20828371 — Surrogate Endpoint (SUR): Blood pressure
Study 9573676 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 27171112 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 27171112 — Safety Biomarker (SAF): Hyaluronic acid
Study 18215600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11827921 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11827921 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 11827921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10070909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10766467 — Predictive Biomarker (PRD): ELOVL6 mRNA
Genes: ELOVL6; FACE; LCE
Study 10766467 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22578498 — Predictive Biomarker (PRD): CA3 mRNA
Genes: CA3
Study 17653020 — Surrogate Endpoint (SUR): Blood pressure
Study 15760627 — Surrogate Endpoint (SUR): Blood pressure
Study 10443734 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 7878758 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 7878758 — Surrogate Endpoint (SUR): Blood pressure
Study 24848627 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22307831 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22307831 — Predictive Biomarker (PRD): OPN1SW mRNA
Genes: OPN1SW; BCP
Study 22307831 — Monitoring Biomarker (MOI): HBV DNA
Study 15037560 — Surrogate Endpoint (SUR): Blood pressure
Study 9263559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11476655 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 29286865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12105139 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12105139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7002949 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24019546 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16458130 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30661220 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 30661220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30661220 — Surrogate Endpoint (SUR): Blood pressure
Study 17372327 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17372327 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23312051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23312051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23312051 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23312051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23312051 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20412373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1743787 — Surrogate Endpoint (SUR): Blood pressure
Study 27271664 — Surrogate Endpoint (SUR): Blood pressure
Study 27271664 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27485808 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27485808 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25723472 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 24565238 — Surrogate Endpoint (SUR): Blood pressure
Study 14759456 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11759784 — Surrogate Endpoint (SUR): Blood pressure
Study 11759784 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27391484 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17473774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15051932 — Surrogate Endpoint (SUR): Serum creatinine
Study 2597519 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 28081288 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25884448 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23228215 — Surrogate Endpoint (SUR): Serum creatinine
Study 23228215 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 15236892 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27110697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22795712 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19064574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19064574 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19064574 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17073955 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 17073955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29912623 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29912623 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29912623 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29912623 — Surrogate Endpoint (SUR): Blood pressure
Study 16647885 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 8625230 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 3158783 — Safety Biomarker (SAF): Reactive oxygen species
Study 19169063 — Surrogate Endpoint (SUR): Blood pressure
Study 8739813 — Surrogate Endpoint (SUR): Blood pressure
Study 2065042 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2065042 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26871534 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22709750 — Surrogate Endpoint (SUR): Blood pressure
Study 19351830 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9534106 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25801408 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12095667 — Surrogate Endpoint (SUR): Blood pressure
Study 27130929 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25769319 — Surrogate Endpoint (SUR): Blood pressure
Study 20587723 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20587723 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20587723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20587723 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18249205 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18249205 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30082749 — Surrogate Endpoint (SUR): Blood pressure
Study 22241639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22241639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20068379 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 17029274 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 17029274 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18849173 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15280527 — Surrogate Endpoint (SUR): Serum creatinine
Study 15280527 — Surrogate Endpoint (SUR): Blood pressure
Study 7121809 — Surrogate Endpoint (SUR): Blood pressure
Study 31796013 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 26932142 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 14699463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11156542 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 9683005 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 9683005 — Surrogate Endpoint (SUR): Blood pressure
Study 22098700 — Surrogate Endpoint (SUR): Blood pressure