TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22233204 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 22233204 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22233204 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 9927022 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7779149 — Surrogate Endpoint (SUR): Blood pressure
Study 9747868 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2893877 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 29212368 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9220319 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25268778 — Surrogate Endpoint (SUR): Blood pressure
Study 18809731 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 28778281 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 22428491 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 19416257 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 9885179 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 8279943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8279943 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 8279943 — Safety Biomarker (SAF): Interleukin 1
Study 8279943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18407467 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 24265159 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24265159 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 11149478 — Surrogate Endpoint (SUR): Bone mineral density
Study 30987432 — Surrogate Endpoint (SUR): Serum creatinine
Study 29696915 — Surrogate Endpoint (SUR): Blood pressure
Study 17571481 — Surrogate Endpoint (SUR): Blood pressure
Study 6923655 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31852846 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30423846 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30423846 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24997559 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29846719 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29846719 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 25667293 — Predictive Biomarker (PRD): UBC mRNA
Genes: UBC
Study 17515729 — Surrogate Endpoint (SUR): Blood pressure
Study 15570253 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15570253 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30140707 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 22318706 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 22318706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8501156 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29604160 — Surrogate Endpoint (SUR): Serum creatinine
Study 29604160 — Surrogate Endpoint (SUR): Blood pressure
Study 23691171 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 19366101 — Surrogate Endpoint (SUR): Bone mineral density
Study 19366101 — Surrogate Endpoint (SUR): Serum calcium
Study 9935227 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7925516 — Surrogate Endpoint (SUR): Blood pressure
Study 336453 — Surrogate Endpoint (SUR): Blood pressure
Study 25743173 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 24613523 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15226466 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15226466 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16203934 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 10090538 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10090538 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26201184 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 14984379 — Monitoring Biomarker (MOI): HBV DNA
Study 9135734 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 9135734 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 8198341 — Surrogate Endpoint (SUR): Blood pressure
Study 25693004 — Surrogate Endpoint (SUR): Blood pressure
Study 11840286 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 11840286 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 11840286 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 7083512 — Surrogate Endpoint (SUR): Blood pressure
Study 16433927 — Surrogate Endpoint (SUR): Blood pressure
Study 14583064 — Surrogate Endpoint (SUR): Blood pressure
Study 6377491 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24913351 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 24913351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24913351 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 9988284 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30461337 — Surrogate Endpoint (SUR): Bone mineral density
Study 20204674 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9019175 — Surrogate Endpoint (SUR): Blood pressure
Study 26764413 — Predictive Biomarker (PRD): HCN4 mRNA
Genes: HCN4
Study 26764413 — Surrogate Endpoint (SUR): Blood pressure
Study 15640476 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12195349 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28667705 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 26444692 — Surrogate Endpoint (SUR): Serum creatinine
Study 21203877 — Surrogate Endpoint (SUR): Blood pressure
Study 23746205 — Surrogate Endpoint (SUR): Blood pressure
Study 23746205 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23746205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23746205 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20305399 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 20305399 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 20305399 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 20305399 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20305399 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16737761 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15381513 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 20145446 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 26072396 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 19550356 — Surrogate Endpoint (SUR): Blood pressure
Study 28290800 — Surrogate Endpoint (SUR): Blood pressure
Study 24131075 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19717481 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15839181 — Surrogate Endpoint (SUR): Blood pressure
Study 8893636 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29229898 — Monitoring Biomarker (MOI): HBV DNA
Study 22971904 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22971904 — Surrogate Endpoint (SUR): Blood pressure
Study 9625220 — Surrogate Endpoint (SUR): Blood pressure
Study 24218528 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 20538557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20538557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16291416 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30829203 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25864739 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 25864739 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 25864739 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 25864739 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 25864739 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25864739 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 24007461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24007461 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21411210 — Surrogate Endpoint (SUR): Blood pressure
Study 9344323 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31295854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31295854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31295854 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23407306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23407306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21124330 — Surrogate Endpoint (SUR): Blood pressure
Study 17996133 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25524834 — Predictive Biomarker (PRD): BOC mRNA
Genes: BOC; UNQ604/PRO1190
Study 23233710 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8955546 — Surrogate Endpoint (SUR): Blood pressure
Study 22002685 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 12689357 — Surrogate Endpoint (SUR): Blood pressure
Study 22607512 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16205597 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16205597 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16205597 — Predictive Biomarker (PRD): Hormone receptor
Study 8901799 — Surrogate Endpoint (SUR): Blood pressure
Study 6848468 — Surrogate Endpoint (SUR): Blood pressure
Study 29480175 — Surrogate Endpoint (SUR): Blood pressure
Study 19821068 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 23529392 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 29348380 — Surrogate Endpoint (SUR): Blood pressure
Study 31436835 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 11434170 — Predictive Biomarker (PRD): TNFRSF25 mRNA
Genes: TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; UNQ455/PRO779
Study 11434170 — Predictive Biomarker (PRD): TOR1B mRNA
Genes: TOR1B; DQ1; FKSG18
Study 11434170 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 841307 — Surrogate Endpoint (SUR): Blood pressure
Study 31141505 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29937865 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23690688 — Surrogate Endpoint (SUR): Blood pressure
Study 9002942 — Surrogate Endpoint (SUR): Blood pressure
Study 28410612 — Predictive Biomarker (PRD): PALM mRNA
Genes: PALM; KIAA0270
Study 10496529 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 10496529 — Predictive Biomarker (PRD): Microsatellite instability
Study 19514089 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15168718 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25050869 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study 25050869 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25050869 — Safety Biomarker (SAF): Urinary microalbumin
Study 21931737 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21931737 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18348715 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 4089582 — Surrogate Endpoint (SUR): Blood pressure
Study 22683613 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22683613 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8334064 — Surrogate Endpoint (SUR): Blood pressure
Study 3769183 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29775957 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 20147846 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 30888975 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 30888975 — Surrogate Endpoint (SUR): Blood pressure
Study 29554282 — Predictive Biomarker (PRD): Hormone receptor
Study 22028294 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 22028294 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 15610252 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21353673 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 31975053 — Predictive Biomarker (PRD): TERF1 mRNA
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study 31740545 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 31740545 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25247908 — Surrogate Endpoint (SUR): Blood pressure
Study 16075824 — Surrogate Endpoint (SUR): Blood pressure
Study 9935200 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 9935200 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 9935200 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 8520164 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8520164 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2106545 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 31753198 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22194217 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 9445307 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9445307 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9445307 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 628361 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 628361 — Surrogate Endpoint (SUR): Serum uric acid
Study 18445058 — Surrogate Endpoint (SUR): Blood pressure
Study 10217000 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10217000 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10217000 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1941668 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 25622538 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 24171842 — Surrogate Endpoint (SUR): Blood pressure
Study 18838053 — Surrogate Endpoint (SUR): Bone mineral density
Study 10942632 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10942632 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10942632 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 27536869 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23200175 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23200175 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 23200175 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study 21391924 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19364873 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 9771299 — Surrogate Endpoint (SUR): Blood pressure
Study 3071596 — Surrogate Endpoint (SUR): Blood pressure
Study 30827971 — Surrogate Endpoint (SUR): Blood pressure
Study 18778179 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18778179 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21809720 — Surrogate Endpoint (SUR): Blood pressure
Study 16138713 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27886078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22314083 — Surrogate Endpoint (SUR): Blood pressure
Study 12803583 — Safety Biomarker (SAF): Reactive oxygen species
Study 30027612 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 9524897 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30481999 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30481999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30481999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28029445 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28029445 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9032192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9032192 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9032192 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9032192 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 9032192 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26758700 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15469666 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3780692 — Surrogate Endpoint (SUR): Blood pressure
Study 30045422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30045422 — Predictive Biomarker (PRD): PNO1 mRNA
Genes: PNO1
Study 25701171 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23069274 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 30282861 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30282861 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22388325 — Surrogate Endpoint (SUR): Blood pressure
Study 10073791 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30107043 — Predictive Biomarker (PRD): Hormone receptor
Study 19874636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31481683 — Predictive Biomarker (PRD): CD200R1 mRNA
Genes: CD200R1; CD200R; CRTR2; MOX2R; OX2R; UNQ2522/PRO6015
Study 31481683 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 26820158 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 12413985 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8101011 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16075363 — Surrogate Endpoint (SUR): Bone mineral density
Study 10189133 — Predictive Biomarker (PRD): Hormone receptor
Study 8944997 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28431533 — Surrogate Endpoint (SUR): Blood pressure
Study 21494767 — Surrogate Endpoint (SUR): Blood pressure
Study 11439795 — Surrogate Endpoint (SUR): Blood pressure
Study 363434 — Surrogate Endpoint (SUR): Blood pressure
Study 28809610 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23441835 — Surrogate Endpoint (SUR): Blood pressure
Study 21221689 — Safety Biomarker (SAF): Interleukin 1
Study 17719468 — Surrogate Endpoint (SUR): Blood pressure
Study 17719468 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10934984 — Surrogate Endpoint (SUR): Blood pressure
Study 1286547 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 27609406 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 9524049 — Surrogate Endpoint (SUR): Blood pressure
Study 19557003 — Surrogate Endpoint (SUR): Blood pressure
Study 19557003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15292745 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 15292745 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30246694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22169080 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 17643572 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30354231 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 22915615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22915615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19126893 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study 19126893 — Safety Biomarker (SAF): Hyaluronic acid
Study 12825127 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24419137 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 10971683 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 10971683 — Predictive Biomarker (PRD): BSN mRNA
Genes: BSN; KIAA0434; ZNF231
Study 6439566 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 6439566 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 28137402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19962185 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16825847 — Surrogate Endpoint (SUR): Blood pressure
Study 8675168 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 6152275 — Surrogate Endpoint (SUR): Blood pressure
Study 19378423 — Safety Biomarker (SAF): Reactive oxygen species
Study 10229744 — Surrogate Endpoint (SUR): Blood pressure
Study 8722437 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21111770 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 15189389 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2563388 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 26357467 — Surrogate Endpoint (SUR): Serum uric acid