TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00211250 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02831049 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01279720 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT03448861 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03283384 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03283384 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02505087 — Predictive Biomarker (PRD): SELENON mRNA
Genes: SELENON; SELN; SEPN1
Study NCT04421300 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01164475 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03687424 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03785821 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study NCT03462979 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02193334 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT05801952 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04913948 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02400853 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT02207608 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01655901 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03385538 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT02733419 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00548327 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02019524 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study NCT04540029 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study NCT04540029 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study NCT04540029 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study NCT04540029 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04540029 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study NCT00600717 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study NCT02709083 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04244019 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT04460508 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04912076 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT02969265 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01734200 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04624828 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT02556749 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06549712 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02609490 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01870596 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study NCT03460080 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT01659151 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03386331 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT04522817 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04318223 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT04318223 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04318223 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04318223 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04318223 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02955823 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT02168803 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02168803 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00000474 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03748186 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT01724268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04044508 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03304639 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03349801 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05124392 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study NCT04005742 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT03994796 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT03994796 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03994796 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03636633 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03636633 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03605199 — Predictive Biomarker (PRD): GCG mRNA
Genes: GCG
Study NCT00917696 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study NCT02598310 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02379390 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00976950 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03351465 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study NCT00789997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01442532 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01948141 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT01669239 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00602368 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01462604 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01401556 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02077218 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study NCT04151355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04151355 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT04480710 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study NCT04315480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00002960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT05304325 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT03838445 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02307682 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01413542 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01413542 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00889993 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT02719236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02719236 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT03278899 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT04649424 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01217814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03997877 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01022346 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01022346 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT02900716 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01625832 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study NCT03560180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02834013 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01823835 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01823835 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00004378 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT02650843 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT03368417 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01821313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01821313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01821313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01821313 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT03206359 — Predictive Biomarker (PRD): PPP1R15A mRNA
Genes: PPP1R15A; GADD34
Study NCT03850314 — Predictive Biomarker (PRD): SHMT2 mRNA
Genes: SHMT2
Study NCT03850314 — Predictive Biomarker (PRD): SREBF2 mRNA
Genes: SREBF2; BHLHD2; SREBP2
Study NCT01089894 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05046678 — Safety Biomarker (SAF): miR-142
Genes: MIR142
Study NCT05046678 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study NCT05046678 — Safety Biomarker (SAF): miR-146b
Genes: MIR146B
Study NCT05046678 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT01401166 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01002937 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT02811224 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03136952 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00964158 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00565656 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03806816 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04744636 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02060318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00846534 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01169207 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study NCT00001316 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03273595 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03273595 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03273595 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03927053 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04606524 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT01799369 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02790515 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01398267 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04846933 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00386633 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00299286 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01090752 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT03150693 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT00001529 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04226157 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04547699 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03479554 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03717142 — Predictive Biomarker (PRD): LUM mRNA
Genes: LUM; LDC; SLRR2D
Study NCT04002947 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT02120157 — Predictive Biomarker (PRD): NRM mRNA
Genes: NRM; NRM29; UNQ555/PRO1112
Study NCT03178812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00013559 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study NCT00001465 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT02701634 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study NCT02765165 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT01888770 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00154869 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01309841 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT03148665 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT01128179 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00520897 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03838497 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06033469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04614415 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02933255 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02538965 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04322565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04322565 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT00300599 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01814553 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00152074 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00111553 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT02226471 — Predictive Biomarker (PRD): C1QTNF3 mRNA
Genes: C1QTNF3; CTRP3; UNQ753/PRO1484
Study NCT02226471 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study NCT00410163 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00410163 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00248053 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT03263975 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02674659 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04777513 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02897245 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02897245 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02568839 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01658410 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT01658410 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT04047862 — Predictive Biomarker (PRD): TIGIT mRNA
Genes: TIGIT; VSIG9; VSTM3
Study NCT00970827 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02115113 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04083898 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT01242787 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00298844 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01756703 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02620280 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00715312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01031485 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02494778 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT02434328 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01755767 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02029157 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04470427 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04470427 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03196141 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04508816 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00042627 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04132219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00557232 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03625128 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03625128 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT04678011 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT02542293 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02542293 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02542293 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04215146 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04215146 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04215146 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04215146 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02851745 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04007653 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT04785755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04785755 — Surrogate Endpoint (SUR): Serum sodium
Study NCT04785755 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01827930 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01827930 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03566316 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00392795 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01551173 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01406444 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00327093 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00327093 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00327093 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00327093 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT02905942 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04504123 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04504123 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02098772 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT04733261 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01994291 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT04905875 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03387566 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03387566 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study NCT03387566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02258581 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02321618 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01991938 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02135471 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT04945811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03489993 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT03489993 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03489993 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT03489993 — Safety Biomarker (SAF): RAS pathway
Study NCT02733328 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT02733328 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01934660 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01189786 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03458260 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03331003 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study NCT03354390 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01596309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01596309 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01596309 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT01596309 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT01596309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00008177 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT04060095 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01998841 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study NCT00856375 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02429440 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF