TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23524525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23524525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23524525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12535750 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 1676394 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25674675 — Surrogate Endpoint (SUR): Blood pressure
Study 24512496 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 19036552 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12707718 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 12707718 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 6339939 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 17268082 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 29099329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29099329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29099329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8654328 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 1386491 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 14526206 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11780187 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11780187 — Surrogate Endpoint (SUR): Blood pressure
Study 3690975 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3690975 — Surrogate Endpoint (SUR): Blood pressure
Study 31676693 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 28526233 — Predictive Biomarker (PRD): FGF7 mRNA
Genes: FGF7; KGF
Study 23610448 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27342494 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10215768 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 10215768 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 30184165 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30184165 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17382029 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17382029 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17382029 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17382029 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9832490 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19390123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19390123 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17617204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10493666 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 10493666 — Predictive Biomarker (PRD): PRLR mRNA
Genes: PRLR
Study 10493666 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 30235049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28490712 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 28246207 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28246207 — Predictive Biomarker (PRD): LOXL2 mRNA
Genes: LOXL2
Study 21240170 — Surrogate Endpoint (SUR): Blood pressure
Study 28971842 — Surrogate Endpoint (SUR): Blood pressure
Study 31470798 — Surrogate Endpoint (SUR): Bacterial count
Study 1283191 — Surrogate Endpoint (SUR): Blood pressure
Study 25499943 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2047947 — Surrogate Endpoint (SUR): Blood pressure
Study 26946727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21795756 — Surrogate Endpoint (SUR): Blood pressure
Study 10445610 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31987323 — Safety Biomarker (SAF): Reactive oxygen species
Study 24062180 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 8518376 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31236568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27834686 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27834686 — Surrogate Endpoint (SUR): Blood pressure
Study 18194979 — Surrogate Endpoint (SUR): Blood pressure
Study 16490024 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14992341 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 14992341 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14992341 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26205091 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 26205091 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 26205091 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 23419098 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 18234554 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 18234554 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18234554 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16464887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9093005 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 24476472 — Surrogate Endpoint (SUR): Blood pressure
Study 10643835 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10643835 — Surrogate Endpoint (SUR): Blood pressure
Study 10643835 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24849434 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 7564784 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1940881 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1940881 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 24854458 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 15935095 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2218781 — Surrogate Endpoint (SUR): Blood pressure
Study 30149476 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23949042 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 14984453 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3047887 — Surrogate Endpoint (SUR): Blood pressure
Study 24250307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24250307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24250307 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 24250307 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21143839 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 21143839 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21143839 — Surrogate Endpoint (SUR): Blood pressure
Study 18402714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15618781 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11875582 — Surrogate Endpoint (SUR): Blood pressure
Study 7799699 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2149388 — Surrogate Endpoint (SUR): Blood pressure
Study 182347 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28830796 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28830796 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28830796 — Predictive Biomarker (PRD): Hormone receptor
Study 7535080 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24346292 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 14570168 — Surrogate Endpoint (SUR): Blood pressure
Study 10199876 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10199876 — Surrogate Endpoint (SUR): Blood pressure
Study 31420467 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 25131839 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25131839 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23303874 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1482735 — Surrogate Endpoint (SUR): Blood pressure
Study 23018438 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 23018438 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 23018438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23018438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23018438 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23018438 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23018438 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23018438 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2152944 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31078338 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 29408760 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29408760 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29408760 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 6123069 — Surrogate Endpoint (SUR): Blood pressure
Study 31369841 — Surrogate Endpoint (SUR): Blood pressure
Study 24075374 — Surrogate Endpoint (SUR): Sperm parameters
Study 16787719 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 16787719 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 16787719 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 16787719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10381039 — Surrogate Endpoint (SUR): Bone mineral density
Study 28958424 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16077391 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16077391 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 6580659 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 30043092 — Surrogate Endpoint (SUR): Blood pressure
Study 26836465 — Surrogate Endpoint (SUR): Blood pressure
Study 22215183 — Surrogate Endpoint (SUR): Bone mineral density
Study 25524327 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 21617159 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17105841 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17105841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11362207 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28818854 — Surrogate Endpoint (SUR): Blood pressure
Study 22369555 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22369555 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17942759 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 15522941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11589260 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8052119 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2856056 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31813739 — Predictive Biomarker (PRD): SLC10A2 mRNA
Genes: SLC10A2; ASBT; ISBT; NTCP2
Study 25828348 — Surrogate Endpoint (SUR): Blood pressure
Study 21422418 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 21422418 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21422418 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19410976 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19410976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16043724 — Surrogate Endpoint (SUR): Blood pressure
Study 26682289 — Predictive Biomarker (PRD): IMMT mRNA
Genes: IMMT; HMP; MIC60; MINOS2; PIG4; PIG52
Study 31873952 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 31873952 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31873952 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31873952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18808630 — Surrogate Endpoint (SUR): Blood pressure
Study 28249030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28249030 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22935052 — Safety Biomarker (SAF): DRD2
Study 17482465 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15764958 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20679619 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8219659 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3305057 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31945066 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22820788 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22820788 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 18275682 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15718036 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 12573274 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 10529526 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 782773 — Surrogate Endpoint (SUR): Blood pressure
Study 27254132 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31484331 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 9477047 — Surrogate Endpoint (SUR): Blood pressure
Study 19526809 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22993294 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 17698196 — Surrogate Endpoint (SUR): Blood pressure
Study 10523401 — Surrogate Endpoint (SUR): Blood pressure
Study 2147831 — Surrogate Endpoint (SUR): Blood pressure
Study 29190741 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29190741 — Safety Biomarker (SAF): BDNF
Study 16413249 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9415513 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 8237624 — Surrogate Endpoint (SUR): Blood pressure
Study 23531633 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 23531633 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3797105 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 18287130 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18287130 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31971952 — Surrogate Endpoint (SUR): Blood pressure
Study 24633595 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24633595 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22533660 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 22533660 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 16463007 — Surrogate Endpoint (SUR): Bone mineral density
Study 30415039 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 25773149 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 25773149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23067363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23067363 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20234783 — Surrogate Endpoint (SUR): Blood pressure
Study 23761102 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 30073496 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9170400 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20974993 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 9792934 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9792934 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30945511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30945511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30945511 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25848890 — Predictive Biomarker (PRD): VIT mRNA
Genes: VIT; UNQ647/PRO1277
Study 23069326 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21172397 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19901920 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 29272211 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24163113 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16899101 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 31622777 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31622777 — Predictive Biomarker (PRD): GIPR mRNA
Genes: GIPR
Study 23628854 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 23628854 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 9439539 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30203327 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 28732650 — Predictive Biomarker (PRD): Hormone receptor
Study 23629558 — Surrogate Endpoint (SUR): Blood pressure
Study 17100723 — Surrogate Endpoint (SUR): Serum creatinine
Study 12795643 — Surrogate Endpoint (SUR): Blood pressure
Study 21254871 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 8839865 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30621562 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26979174 — Predictive Biomarker (PRD): BCAR1 mRNA
Genes: BCAR1; CAS; CASS1; CRKAS
Study 26979174 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22646056 — Surrogate Endpoint (SUR): Blood pressure
Study 4593130 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 4593130 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25432773 — Surrogate Endpoint (SUR): Bone mineral density
Study 21727175 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19553414 — Surrogate Endpoint (SUR): Blood pressure
Study 29412458 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 27074824 — Surrogate Endpoint (SUR): Serum potassium
Study 22954020 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 22954020 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 12815479 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 21369670 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10620003 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1627957 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 30189773 — Safety Biomarker (SAF): Reactive oxygen species
Study 16036044 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10203381 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24924522 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10208998 — Predictive Biomarker (PRD): HES1 mRNA
Genes: HES1; BHLHB39; HL; HRY
Study 2142911 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31554917 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 31554917 — Predictive Biomarker (PRD): ITGAX mRNA
Genes: ITGAX; CD11C
Study 31554917 — Predictive Biomarker (PRD): MRC1 mRNA
Genes: MRC1; CLEC13D; CLEC13DL; MRC1L1
Study 31554917 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27197120 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27197120 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24374394 — Predictive Biomarker (PRD): HR mRNA
Genes: HR