TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00554632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01508325 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02962479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03045796 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04329195 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03307902 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02865447 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02266693 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT04105335 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study NCT03933475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00379964 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02670811 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04156490 — Surrogate Endpoint (SUR): Serum sodium
Study NCT02411253 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01425203 — Predictive Biomarker (PRD): BOC mRNA
Genes: BOC; UNQ604/PRO1190
Study NCT02419287 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT05350397 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03700307 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03700307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01456676 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01456676 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00153582 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT00153582 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01338415 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01829256 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01900600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01900600 — Safety Biomarker (SAF): Interleukin 1
Study NCT03237065 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00167219 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study NCT03532867 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00864955 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study NCT02218931 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04146610 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00741520 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03324997 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04492683 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT02178137 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT00514943 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04233723 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00934349 — Predictive Biomarker (PRD): TKTL1 mRNA
Genes: TKTL1; TKR; TKT2
Study NCT02973737 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03416543 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study NCT03709407 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01279161 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study NCT00990197 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03498404 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT03498404 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT03498404 — Safety Biomarker (SAF): Interleukin 1
Study NCT03498404 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study NCT03498404 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03498404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02965963 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03705195 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study NCT02007746 — Predictive Biomarker (PRD): Liver iron
Study NCT02817568 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT00867815 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT03215004 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00140582 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT03440164 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT03933982 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03933982 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03933982 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study NCT03786549 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00241839 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03193099 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00004428 — Predictive Biomarker (PRD): CPOX mRNA
Genes: CPOX; CPO; CPX
Study NCT02028403 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00992667 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04567212 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study NCT00784966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01758250 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04420598 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04420598 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02812862 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT00920660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02432768 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03646396 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01544998 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study NCT01544998 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study NCT01442883 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02561832 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00375726 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04609462 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03993106 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02367833 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT04276948 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00020540 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT00390104 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00390104 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT02618109 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00424541 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03566485 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT03566485 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT03566485 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03464045 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT06314555 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06314555 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02321709 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT02321709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03154411 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04436848 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT00439582 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00439582 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03612752 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03612752 — Safety Biomarker (SAF): BDNF
Study NCT05821881 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02432391 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT03186742 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00005604 — Safety Biomarker (SAF): Interleukin 12
Study NCT00005604 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02278367 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02648061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03748680 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03121599 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT03121599 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study NCT03121599 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT02512029 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04116112 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03968224 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00028990 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04547205 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT02707471 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03759535 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02598583 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT02670382 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00836212 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT00174083 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03366922 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04084886 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study NCT04469764 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03869697 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT00387894 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00387894 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT01171092 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02433067 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04062448 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00800605 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study NCT01455181 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02349698 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04558190 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01928160 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01928160 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04442841 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00679705 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02677519 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04982185 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT01710319 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03923400 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT03923400 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT03923400 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study NCT03923400 — Predictive Biomarker (PRD): ANO1 mRNA
Genes: ANO1; DOG1; ORAOV2; TAOS2; TMEM16A
Study NCT03576547 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03576547 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01509040 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03999697 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT00104819 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04624776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03391921 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00865020 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02154412 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01570634 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT01582308 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04562051 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03373604 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02947542 — Predictive Biomarker (PRD): BLK mRNA
Genes: BLK
Study NCT02422199 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01526512 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02969057 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03254589 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04255056 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03206697 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT00727090 — Surrogate Endpoint (SUR): Serum sodium
Study NCT02699424 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02876549 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT00854282 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00854282 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT02827448 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT01592981 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03936504 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT02743260 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT02743260 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study NCT00875537 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT00875537 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study NCT00875537 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02365818 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01572467 — Predictive Biomarker (PRD): DICER1 mRNA
Genes: DICER1; DICER; HERNA; KIAA0928
Study NCT02591550 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT02591550 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study NCT04447495 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01256437 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02200380 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02354352 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00438932 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00322127 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00322127 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00322127 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04644809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04639622 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study NCT04639622 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04639622 — Pharmacodynamic Biomarker (PDY): Guanine nucleotide exchange factor C9orf72
Genes: C9orf72; DENND9; DENNL72
Study NCT01312597 — Safety Biomarker (SAF): BDNF
Study NCT04230174 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT03156400 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02062996 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03407989 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00846092 — Safety Biomarker (SAF): Cytochrome c
Study NCT02721472 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT02532738 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03283176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03729388 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT03729388 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03729388 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT03729388 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02608255 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02351856 — Predictive Biomarker (PRD): LMNA mRNA
Genes: LMNA; LMN1
Study NCT01928797 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00200473 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01318239 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01039376 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04814316 — Surrogate Endpoint (SUR): Serum calcium
Study NCT04814316 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT02113150 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT01069419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01537016 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT04040634 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04445506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03751319 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT03870737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study NCT00759174 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT00252707 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04470076 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04470076 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02407678 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study NCT03487536 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00005458 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02064387 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03079843 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03623529 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT00433082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03770988 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03439332 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study NCT00891670 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01032122 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02988895 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00464776 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03404258 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03644472 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01948843 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03214666 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study NCT03214666 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT01446042 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00184678 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04578236 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT04578236 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04578236 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00299169 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01972893 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04310371 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02575690 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03680495 — Predictive Biomarker (PRD): TSC22D3 mRNA
Genes: TSC22D3; DSIPI; GILZ
Study NCT02727283 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01424878 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01609842 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01218607 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01652573 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828