TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20404743 — Surrogate Endpoint (SUR): Blood pressure
Study 16080364 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 1538350 — Surrogate Endpoint (SUR): Blood pressure
Study 31497674 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30577757 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 15805342 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 2324655 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 26467301 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16778332 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16778332 — Surrogate Endpoint (SUR): Blood pressure
Study 31929199 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12831816 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12831816 — Surrogate Endpoint (SUR): Blood pressure
Study 17725245 — Surrogate Endpoint (SUR): Blood pressure
Study 10401013 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 7743697 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23047822 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17304449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11515595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21884030 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21522069 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 12881011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10792132 — Surrogate Endpoint (SUR): Blood pressure
Study 3485398 — Surrogate Endpoint (SUR): Blood pressure
Study 12682876 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 24720918 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 20562124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1581716 — Surrogate Endpoint (SUR): Blood pressure
Study 19225062 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30165750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7986315 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30982442 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26003264 — Surrogate Endpoint (SUR): Blood pressure
Study 23305646 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 26695667 — Monitoring Biomarker (MOI): Procalcitonin
Study 21255035 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 8769625 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8769625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8769625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8769625 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 3532771 — Surrogate Endpoint (SUR): Blood pressure
Study 3532771 — Surrogate Endpoint (SUR): Serum calcium
Study 31636023 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 16134315 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 20931531 — Predictive Biomarker (PRD): GJB2 mRNA
Genes: GJB2
Study 20931531 — Predictive Biomarker (PRD): SLC26A4 mRNA
Genes: SLC26A4; PDS
Study 28415636 — Surrogate Endpoint (SUR): Serum creatinine
Study 16714361 — Surrogate Endpoint (SUR): Blood pressure
Study 9215232 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9215232 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9215232 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27155586 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 27155586 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 15717632 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 1918709 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30134967 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 22805313 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22805313 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3241259 — Surrogate Endpoint (SUR): Blood pressure
Study 31582622 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27875094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14648073 — Surrogate Endpoint (SUR): Serum calcium
Study 28978818 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 28386781 — Surrogate Endpoint (SUR): Blood pressure
Study 10813543 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10813543 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28407661 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28407661 — Surrogate Endpoint (SUR): Blood pressure
Study 18316567 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 18316567 — Predictive Biomarker (PRD): STAT2 mRNA
Genes: STAT2
Study 14504154 — Surrogate Endpoint (SUR): Blood pressure
Study 21565796 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21565796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25810334 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20697028 — Surrogate Endpoint (SUR): Blood pressure
Study 8918410 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 24919569 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24919569 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24919569 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 24919569 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24919569 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18158078 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 11394244 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30704577 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 18289446 — Surrogate Endpoint (SUR): Blood pressure
Study 12559660 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11038077 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 26465791 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 26465791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22246619 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10878693 — Surrogate Endpoint (SUR): Blood pressure
Study 30816148 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 30816148 — Surrogate Endpoint (SUR): Blood pressure
Study 16574937 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 16574937 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 14606080 — Monitoring Biomarker (MOI): HBV DNA
Study 1544695 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 1544695 — Surrogate Endpoint (SUR): Serum testosterone
Study 31074689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26911833 — Surrogate Endpoint (SUR): Blood pressure
Study 24290367 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24290367 — Safety Biomarker (SAF): BDNF
Study 22914621 — Predictive Biomarker (PRD): HCAR2 mRNA
Genes: HCAR2; GPR109A; HCA2; HM74A; NIACR1
Study 22914621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20551965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20551965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1678921 — Surrogate Endpoint (SUR): Blood pressure
Study 25267980 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23453178 — Surrogate Endpoint (SUR): Blood pressure
Study 18004586 — Surrogate Endpoint (SUR): Blood pressure
Study 9022539 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15030101 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 9036801 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 31780004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29482973 — Surrogate Endpoint (SUR): Serum creatinine
Study 24609624 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10472319 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9122015 — Surrogate Endpoint (SUR): Blood pressure
Study 30830386 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 30830386 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 24886541 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 23206461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30413184 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 30413184 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 18924648 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12727155 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 3886710 — Surrogate Endpoint (SUR): Serum uric acid
Study 2195929 — Surrogate Endpoint (SUR): Bone mineral density
Study 31909809 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 15341540 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 12107516 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 31793486 — Surrogate Endpoint (SUR): Blood pressure
Study 28213205 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 28213205 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28213205 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 19266829 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 22551208 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 20206069 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 20206069 — Surrogate Endpoint (SUR): Serum creatinine
Study 20206069 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 17633369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1689934 — Surrogate Endpoint (SUR): Serum potassium
Study 17540594 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 15513276 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28592575 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19996505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15492353 — Surrogate Endpoint (SUR): Blood pressure
Study 8625186 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2187651 — Surrogate Endpoint (SUR): Blood pressure
Study 6996137 — Surrogate Endpoint (SUR): Blood pressure
Study 30005707 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 6961760 — Surrogate Endpoint (SUR): Blood pressure
Study 25129881 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22232563 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22232563 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14618287 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 9712233 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3044869 — Surrogate Endpoint (SUR): Blood pressure
Study 26390092 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 26390092 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 21135704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9313712 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 29848153 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 29848153 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 29848153 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study 29848153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30241509 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 25647283 — Surrogate Endpoint (SUR): Blood pressure
Study 23443764 — Surrogate Endpoint (SUR): Blood pressure
Study 9146853 — Surrogate Endpoint (SUR): Blood pressure
Study 3218950 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 31778823 — Safety Biomarker (SAF): APC
Genes: DP2; DP3; DP2.5; PPP1R46
Study 14738210 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 14738210 — Surrogate Endpoint (SUR): Blood pressure
Study 8485793 — Surrogate Endpoint (SUR): Blood pressure
Study 24014134 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 14608143 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10663966 — Predictive Biomarker (PRD): CASP3 mRNA
Genes: CASP3; CPP32
Study 1464075 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1464075 — Monitoring Biomarker (MOI): Complement C4
Study 2866062 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2866062 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31969201 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 30297313 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23771989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15902989 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23671213 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9649716 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28601627 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15050908 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 14989462 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 31522612 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 22832126 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 12412826 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17069099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17069099 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17069099 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31800611 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 19534614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9514534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9514534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9514534 — Safety Biomarker (SAF): Interleukin 1
Study 25915834 — Safety Biomarker (SAF): Interleukin 1
Study 18385391 — Surrogate Endpoint (SUR): Serum calcium
Study 18385391 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 16437738 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12915954 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 29731121 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27833172 — Predictive Biomarker (PRD): MSMB mRNA
Genes: MSMB; PRSP
Study 29453374 — Surrogate Endpoint (SUR): Blood pressure
Study 18663165 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31008751 — Surrogate Endpoint (SUR): Serum potassium
Study 24616335 — Surrogate Endpoint (SUR): Blood pressure
Study 2409371 — Surrogate Endpoint (SUR): Blood pressure
Study 12916011 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29570512 — Surrogate Endpoint (SUR): Blood pressure
Study 8116059 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 8964641 — Surrogate Endpoint (SUR): Blood pressure
Study 14630885 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14630885 — Surrogate Endpoint (SUR): Blood pressure
Study 8671857 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8671857 — Surrogate Endpoint (SUR): Blood pressure
Study 1315826 — Surrogate Endpoint (SUR): Blood pressure
Study 20299607 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20299607 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12675179 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 30844848 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study 25099071 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25099071 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 25099071 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23362296 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23362296 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20844049 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 20844049 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20844049 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 15671215 — Surrogate Endpoint (SUR): Blood pressure
Study 15671215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10933617 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9016421 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9016421 — Surrogate Endpoint (SUR): Bone mineral density
Study 29878617 — Safety Biomarker (SAF): Hyaluronic acid
Study 14583178 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 9987171 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 3521691 — Surrogate Endpoint (SUR): Blood pressure
Study 27605230 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27605230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 27605230 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8034872 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29798120 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 9408065 — Surrogate Endpoint (SUR): Blood pressure
Study 27740618 — Surrogate Endpoint (SUR): Blood pressure
Study 25007667 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7856526 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1950173 — Surrogate Endpoint (SUR): Blood pressure
Study 30929965 — Safety Biomarker (SAF): Hyaluronic acid
Study 25963404 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 25963404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 8324915 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 3540308 — Surrogate Endpoint (SUR): Blood pressure
Study 30208589 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 23845320 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18829508 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16485512 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1743319 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 30740935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24342820 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 24342820 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24342820 — Predictive Biomarker (PRD): SLC25A3 mRNA
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 17580725 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 31593528 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 8887059 — Predictive Biomarker (PRD): EIF2AK2 mRNA
Genes: EIF2AK2; PKR; PRKR
Study 1712273 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 6761849 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 30738426 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 25974251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21076273 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19772786 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 15593057 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 15593057 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15593057 — Safety Biomarker (SAF): Interleukin 1
Study 8072255 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 3134810 — Surrogate Endpoint (SUR): Blood pressure
Study 23826093 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 21950148 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9802627 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29993218 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 29206824 — Surrogate Endpoint (SUR): Serum creatinine
Study 26136585 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD