TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30878623 — Surrogate Endpoint (SUR): Blood pressure
Study 15257742 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 30851442 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 24301237 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 30358109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30358109 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30358109 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 30358109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30358109 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 19058981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6849746 — Surrogate Endpoint (SUR): Blood pressure
Study 31344451 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31344451 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23886675 — Predictive Biomarker (PRD): SV2C mRNA
Genes: SV2C; KIAA1054
Study 17909087 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29325658 — Surrogate Endpoint (SUR): Blood pressure
Study 27695785 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 22033034 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 11593504 — Monitoring Biomarker (MOI): HBV DNA
Study 8911885 — Surrogate Endpoint (SUR): Serum calcium
Study 31608454 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31608454 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 31608454 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 22159910 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20565296 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 3073868 — Monitoring Biomarker (MOI): HBV DNA
Study 30553700 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 7700071 — Surrogate Endpoint (SUR): Blood pressure
Study 7700071 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31853543 — Surrogate Endpoint (SUR): Blood pressure
Study 27206810 — Surrogate Endpoint (SUR): Blood pressure
Study 25782469 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH
Study 23453866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2526031 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2526031 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31101403 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 31101403 — Surrogate Endpoint (SUR): Blood pressure
Study 28276521 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 28276521 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22422736 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 16299295 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1924079 — Surrogate Endpoint (SUR): Blood pressure
Study 27523954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7498559 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 26138425 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 26138425 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 26138425 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18374327 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18374327 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12559540 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22954616 — Safety Biomarker (SAF): BDNF
Study 11908492 — Surrogate Endpoint (SUR): Bone mineral density
Study 11908492 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 8903836 — Surrogate Endpoint (SUR): Blood pressure
Study 19917838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19917838 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28956658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10930149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29905759 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29905759 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25518015 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 22448451 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 18397979 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 16463851 — Surrogate Endpoint (SUR): Blood pressure
Study 6128230 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 20557905 — Monitoring Biomarker (MOI): Procalcitonin
Study 10529122 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10529122 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 10529122 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 10529122 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 10529122 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10529122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8622104 — Surrogate Endpoint (SUR): Serum creatinine
Study 25657175 — Surrogate Endpoint (SUR): Blood pressure
Study 23835929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17538978 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15801935 — Surrogate Endpoint (SUR): Blood pressure
Study 6407352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6407352 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 27586538 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27586538 — Surrogate Endpoint (SUR): Blood pressure
Study 15193814 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12904184 — Surrogate Endpoint (SUR): Blood pressure
Study 10678614 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9042816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9042816 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17618955 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17618955 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7782427 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 10878653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30863396 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study 30408271 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 27269946 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27269946 — Predictive Biomarker (PRD): Hormone receptor
Study 24899464 — Surrogate Endpoint (SUR): Blood pressure
Study 24899464 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22126936 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22126936 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22126936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10483896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10483896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25557828 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12952836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1756257 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 6802691 — Surrogate Endpoint (SUR): Blood pressure
Study 29562396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28228504 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25592751 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 25592751 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24151277 — Surrogate Endpoint (SUR): Bone mineral density
Study 15284267 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 31448433 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 31448433 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 31448433 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 31448433 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 1753422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6760378 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30442864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25083759 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 18341601 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 19916254 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30272088 — Surrogate Endpoint (SUR): Blood pressure
Study 16134756 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12270246 — Surrogate Endpoint (SUR): Serum potassium
Study 2483328 — Surrogate Endpoint (SUR): Blood pressure
Study 28398846 — Predictive Biomarker (PRD): Hormone receptor
Study 24081946 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 9302209 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9302209 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26906165 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21609286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18937813 — Surrogate Endpoint (SUR): Blood pressure
Study 29128208 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10710132 — Surrogate Endpoint (SUR): Blood pressure
Study 8648387 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18505783 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 12629058 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10537443 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19860749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 17606957 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17606957 — Surrogate Endpoint (SUR): Serum creatinine
Study 10439747 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 10439747 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2087863 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 31064236 — Safety Biomarker (SAF): Hyaluronic acid
Study 26704712 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19963099 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 17407035 — Surrogate Endpoint (SUR): Serum antibody concentration
Study 11233898 — Monitoring Biomarker (MOI): HBV DNA
Study 21977941 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30512100 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 26429068 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 19172131 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19172131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15939062 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10591888 — Surrogate Endpoint (SUR): Blood pressure
Study 1776257 — Surrogate Endpoint (SUR): Blood pressure
Study 23364953 — Monitoring Biomarker (MOI): HBV DNA
Study 21295383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27154411 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7521788 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30980316 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19442975 — Surrogate Endpoint (SUR): Blood pressure
Study 17116939 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 9226731 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29671256 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29671256 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 29671256 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 26259892 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20214694 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 19787599 — Surrogate Endpoint (SUR): Blood pressure
Study 22858074 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21094356 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18678838 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18678838 — Predictive Biomarker (PRD): Hormone receptor
Study 6379275 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 26289619 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 26289619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26289619 — Safety Biomarker (SAF): Reactive oxygen species
Study 26289619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24316175 — Surrogate Endpoint (SUR): Blood pressure
Study 21711438 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 17145137 — Surrogate Endpoint (SUR): Serum testosterone
Study 3513821 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 3513821 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 24170641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21380981 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 21380981 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10928300 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10928300 — Surrogate Endpoint (SUR): Blood pressure
Study 31719145 — Predictive Biomarker (PRD): HDAC6 mRNA
Genes: HDAC6; KIAA0901; JM21
Study 31719145 — Predictive Biomarker (PRD): NOS3 mRNA
Genes: NOS3
Study 14501381 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10323688 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1930858 — Surrogate Endpoint (SUR): Blood pressure
Study 21635709 — Predictive Biomarker (PRD): Hormone receptor
Study 8730003 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1846438 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1846438 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11731687 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 27265388 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 9335416 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9335416 — Surrogate Endpoint (SUR): Blood pressure
Study 9335416 — Surrogate Endpoint (SUR): Serum potassium
Study 3021083 — Surrogate Endpoint (SUR): Blood pressure
Study 27699819 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21273209 — Surrogate Endpoint (SUR): Blood pressure
Study 7755459 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7755459 — Surrogate Endpoint (SUR): Blood pressure
Study 26500862 — Safety Biomarker (SAF): PRSs score
Study 23509322 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23509322 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9676024 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8742796 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 31992604 — Surrogate Endpoint (SUR): Blood pressure
Study 31199103 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 28075499 — Surrogate Endpoint (SUR): Blood pressure
Study 7761010 — Surrogate Endpoint (SUR): Blood pressure
Study 27473445 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17488457 — Surrogate Endpoint (SUR): Blood pressure
Study 8903618 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8903618 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 11527126 — Surrogate Endpoint (SUR): Blood pressure
Study 11527126 — Surrogate Endpoint (SUR): Serum potassium
Study 23407853 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 19939876 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 11487548 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 11487548 — Surrogate Endpoint (SUR): Serum sodium
Study 9851896 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 26645407 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25551934 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 25551934 — Surrogate Endpoint (SUR): Bone mineral density
Study 30882555 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 15167313 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15167313 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11181465 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 22010585 — Surrogate Endpoint (SUR): Blood pressure
Study 16448518 — Surrogate Endpoint (SUR): Blood pressure
Study 16448518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25424689 — Surrogate Endpoint (SUR): Blood pressure
Study 24034661 — Surrogate Endpoint (SUR): Blood pressure
Study 19398081 — Surrogate Endpoint (SUR): Blood pressure
Study 8484510 — Surrogate Endpoint (SUR): Blood pressure
Study 24506666 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 24506666 — Safety Biomarker (SAF): Hyaluronic acid
Study 22972032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20632513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18046293 — Surrogate Endpoint (SUR): Blood pressure
Study 2449651 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 26475054 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7898828 — Surrogate Endpoint (SUR): Bone mineral density
Study 7898828 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24118688 — Surrogate Endpoint (SUR): Blood pressure
Study 24118688 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19791825 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19791825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19791825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2884191 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 25127372 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 12151927 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17110825 — Surrogate Endpoint (SUR): Blood pressure
Study 6732937 — Surrogate Endpoint (SUR): Blood pressure
Study 21239359 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12406534 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 8546171 — Surrogate Endpoint (SUR): Serum creatinine
Study 30471384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30471384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30471384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30121808 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 6132891 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24980672 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24980672 — Surrogate Endpoint (SUR): Blood pressure
Study 14871429 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 27316489 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 18841790 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 10399449 — Surrogate Endpoint (SUR): Blood pressure
Study 7551323 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7033789 — Surrogate Endpoint (SUR): Serum alkaline phosphatase and bilirubin
Study 7033789 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18083374 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 11934652 — Surrogate Endpoint (SUR): Bone mineral density
Study 11934652 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9257425 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8400081 — Safety Biomarker (SAF): Reactive oxygen species
Study 3037835 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19025306 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 30106834 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2