TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20880552 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 27245056 — Surrogate Endpoint (SUR): Bone mineral density
Study 24311515 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 22203134 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 10491451 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8367920 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 8367920 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 31578169 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10934908 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8071050 — Surrogate Endpoint (SUR): Blood pressure
Study 3338250 — Surrogate Endpoint (SUR): Blood pressure
Study 10928293 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3710012 — Surrogate Endpoint (SUR): Blood pressure
Study 3710012 — Safety Biomarker (SAF): 51Cr-EDTA
Study 27916047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27916047 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 12009244 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 31081862 — Surrogate Endpoint (SUR): Blood pressure
Study 25305506 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25305506 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 25305506 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 21865946 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21865946 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 21865946 — Safety Biomarker (SAF): MTHFR
Study 19262477 — Surrogate Endpoint (SUR): Blood pressure
Study 16752259 — Predictive Biomarker (PRD): SLC11A1 mRNA
Genes: SLC11A1; LSH; NRAMP; NRAMP1
Study 30796122 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30796122 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27640067 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 27640067 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 20102922 — Surrogate Endpoint (SUR): Blood pressure
Study 20102922 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23126345 — Surrogate Endpoint (SUR): Blood pressure
Study 12616983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12616983 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12616983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6127888 — Surrogate Endpoint (SUR): Blood pressure
Study 26395743 — Predictive Biomarker (PRD): GLUL mRNA
Genes: GLUL; GLNS
Study 24944131 — Surrogate Endpoint (SUR): Blood pressure
Study 17192324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15051570 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study 31466276 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 24029542 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 24029542 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 24029542 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 9562691 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2894548 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18315784 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 18315784 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18315784 — Safety Biomarker (SAF): Reactive oxygen species
Study 17023870 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 17023870 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 26443696 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29617381 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25208561 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25208561 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31779479 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 30566590 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23795737 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20153154 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 15554359 — Predictive Biomarker (PRD): TSHR mRNA
Genes: TSHR; LGR3
Study 11499801 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27506909 — Surrogate Endpoint (SUR): Blood pressure
Study 26464000 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12483466 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7570730 — Surrogate Endpoint (SUR): Blood pressure
Study 11309322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22057076 — Surrogate Endpoint (SUR): Bone mineral density
Study 9920455 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27565240 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27565240 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12079930 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9617439 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 2721119 — Surrogate Endpoint (SUR): Blood pressure
Study 20938210 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 3827416 — Surrogate Endpoint (SUR): Blood pressure
Study 9378830 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 3017391 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24884578 — Surrogate Endpoint (SUR): Serum creatinine
Study 20298851 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 665656 — Surrogate Endpoint (SUR): Blood pressure
Study 31473412 — Surrogate Endpoint (SUR): Blood pressure
Study 7529528 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3278431 — Surrogate Endpoint (SUR): Serum creatinine
Study 12559678 — Surrogate Endpoint (SUR): Blood pressure
Study 9352695 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8462384 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8462384 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3081923 — Surrogate Endpoint (SUR): Blood pressure
Study 30027590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 17669242 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 29791829 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29791829 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27161018 — Surrogate Endpoint (SUR): Blood pressure
Study 24624911 — Predictive Biomarker (PRD): ABCC4 mRNA
Genes: ABCC4; MOATB; MRP4
Study 24624911 — Predictive Biomarker (PRD): ABCC5 mRNA
Genes: ABCC5; MRP5
Study 24624911 — Predictive Biomarker (PRD): IMPDH1 mRNA
Genes: IMPDH1; IMPD1
Study 24624911 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 24624911 — Predictive Biomarker (PRD): CNT3 mRNA
Genes: SLC28A3; CNT3
Study 24624911 — Predictive Biomarker (PRD): XDH mRNA
Genes: XDH; XDHA
Study 24624911 — Predictive Biomarker (PRD): ATP6AP2 mRNA
Genes: ATP6AP2; ATP6IP2; CAPER; ELDF10; HT028; MSTP009; PSEC0072
Study 24624911 — Predictive Biomarker (PRD): FRMD4B mRNA
Genes: FRMD4B; GRSP1; KIAA1013
Study 24624911 — Predictive Biomarker (PRD): GNG2 mRNA
Genes: GNG2
Study 24624911 — Predictive Biomarker (PRD): KCNMA1 mRNA
Genes: KCNMA1; KCNMA; SLO
Study 24624911 — Predictive Biomarker (PRD): NME1 mRNA
Genes: NME1; NDPKA; NM23
Study 23394510 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 23394510 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 18757663 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23857436 — Predictive Biomarker (PRD): DIAPH2 mRNA
Genes: DIAPH2; DIA
Study 7981446 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31426673 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22964434 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 15076648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15076648 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11425688 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25517389 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25517389 — Surrogate Endpoint (SUR): Blood pressure
Study 3687684 — Surrogate Endpoint (SUR): Blood pressure
Study 19014834 — Surrogate Endpoint (SUR): Blood pressure
Study 19014834 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29608685 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26869191 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19962297 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19962297 — Surrogate Endpoint (SUR): Blood pressure
Study 19962297 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15809885 — Predictive Biomarker (PRD): Liver iron
Study 12034649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7836086 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 2239759 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 23731234 — Surrogate Endpoint (SUR): Serum creatinine
Study 11159266 — Surrogate Endpoint (SUR): Blood pressure
Study 23590671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20530222 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12438559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7562881 — Surrogate Endpoint (SUR): Blood pressure
Study 6274563 — Surrogate Endpoint (SUR): Blood pressure
Study 17472226 — Surrogate Endpoint (SUR): Blood pressure
Study 14685950 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 24532276 — Surrogate Endpoint (SUR): Blood pressure
Study 18720710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15802415 — Surrogate Endpoint (SUR): Blood pressure
Study 11787475 — Surrogate Endpoint (SUR): Blood pressure
Study 1989736 — Surrogate Endpoint (SUR): Blood pressure
Study 22036036 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 22036036 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 22036036 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 22036036 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 19769634 — Surrogate Endpoint (SUR): Serum creatinine
Study 19769634 — Surrogate Endpoint (SUR): Serum potassium
Study 17291843 — Surrogate Endpoint (SUR): Bone mineral density
Study 16321186 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 16321186 — Surrogate Endpoint (SUR): Bone mineral density
Study 19050164 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 19050164 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 19050164 — Surrogate Endpoint (SUR): Serum testosterone
Study 19050164 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 790125 — Surrogate Endpoint (SUR): Blood pressure
Study 25133710 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Growth/differentiation factor 8
Genes: MSTN; GDF8
Study 25133710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25133710 — Safety Biomarker (SAF): Interleukin 1
Study 25133710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23925417 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17032095 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 10386471 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26343594 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 31712711 — Surrogate Endpoint (SUR): Blood pressure
Study 31316148 — Surrogate Endpoint (SUR): Serum sodium
Study 31316148 — Surrogate Endpoint (SUR): Serum creatinine
Study 25870177 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 21775917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21775917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21775917 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16150196 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 16150196 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7979299 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25256070 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25256070 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19914557 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 14998945 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14998945 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28821512 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 10371375 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2072836 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 2072836 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 2072836 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22024668 — Surrogate Endpoint (SUR): Blood pressure
Study 19503772 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19503772 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7726705 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29284097 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 27424687 — Surrogate Endpoint (SUR): Serum creatinine
Study 15717257 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10944134 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10944134 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 10944134 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 20535016 — Surrogate Endpoint (SUR): Blood pressure
Study 16170642 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 1372855 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20131276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30983087 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23627803 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 20497250 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20497250 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15262190 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7586773 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 7586773 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 7586773 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 20522672 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16434753 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16434753 — Surrogate Endpoint (SUR): Blood pressure
Study 10363564 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30586756 — Surrogate Endpoint (SUR): Blood pressure
Study 23054852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20386062 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 16177615 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 12529344 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6897369 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 29921393 — Surrogate Endpoint (SUR): Blood pressure
Study 12226016 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8122946 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8122946 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28033544 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 28033544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23788809 — Surrogate Endpoint (SUR): Blood pressure
Study 14625121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2934579 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 26547291 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 26547291 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12847067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6363078 — Surrogate Endpoint (SUR): Blood pressure
Study 30906769 — Predictive Biomarker (PRD): CASP8 mRNA
Genes: CASP8; MCH5
Study 29310645 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 20354834 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 18622600 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12598065 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12598065 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 359398 — Surrogate Endpoint (SUR): Blood pressure
Study 21768453 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15504138 — Surrogate Endpoint (SUR): Blood pressure
Study 15504138 — Surrogate Endpoint (SUR): Serum creatinine
Study 11342919 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 11342919 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 23717976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22107692 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 22107692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19035979 — Surrogate Endpoint (SUR): Bone mineral density
Study 235714 — Surrogate Endpoint (SUR): Blood pressure
Study 28477375 — Surrogate Endpoint (SUR): Blood pressure
Study 1587959 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22898340 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 3237227 — Surrogate Endpoint (SUR): Blood pressure
Study 30450925 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 23875668 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16758263 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9103732 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6376596 — Surrogate Endpoint (SUR): Blood pressure
Study 18551025 — Surrogate Endpoint (SUR): Blood pressure
Study 2027481 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 2027481 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6418647 — Surrogate Endpoint (SUR): Blood pressure
Study 30651222 — Surrogate Endpoint (SUR): Blood pressure
Study 26250523 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29895599 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 27716694 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 9164900 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8388880 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8388880 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 28642330 — Surrogate Endpoint (SUR): Blood pressure
Study 24450891 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24450891 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21848927 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8950073 — Surrogate Endpoint (SUR): Blood pressure
Study 6957982 — Predictive Biomarker (PRD): PIR mRNA
Genes: PIR
Study 19140095 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10750752 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10750752 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 1529939 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1529939 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1529939 — Surrogate Endpoint (SUR): Serum triglycerides
Study 4074606 — Surrogate Endpoint (SUR): Blood pressure
Study 3304706 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28288611 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 9089669 — Surrogate Endpoint (SUR): Blood pressure
Study 4013627 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25611082 — Surrogate Endpoint (SUR): Blood pressure
Study 25190728 — Predictive Biomarker (PRD): UGT2A1 mRNA
Genes: UGT2A1
Study 25190728 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 25190728 — Predictive Biomarker (PRD): E2F5 mRNA
Genes: E2F5
Study 25190728 — Predictive Biomarker (PRD): BUB1 mRNA
Genes: BUB1; BUB1L
Study 25190728 — Predictive Biomarker (PRD): CCNB2 mRNA
Genes: CCNB2
Study 25190728 — Predictive Biomarker (PRD): MYBL2 mRNA
Genes: MYBL2; BMYB
Study 25190728 — Pharmacodynamic Biomarker (PDY): Cyclin-dependent kinase 1
Genes: CDK1; CDC2; CDC28A; CDKN1; P34CDC2
Study 25190728 — Predictive Biomarker (PRD): CDC20 mRNA
Genes: CDC20
Study 16798622 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16798622 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1526085 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1526085 — Surrogate Endpoint (SUR): Blood pressure
Study 3532744 — Surrogate Endpoint (SUR): Blood pressure
Study 30452706 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30452706 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol