TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22257577 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 15797163 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2050319 — Monitoring Biomarker (MOI): HBV DNA
Study 1101478 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 31283908 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 26334853 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23004922 — Surrogate Endpoint (SUR): Blood pressure
Study 10929272 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20969725 — Surrogate Endpoint (SUR): Blood pressure
Study 15547093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11560099 — Surrogate Endpoint (SUR): Blood pressure
Study 26430087 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 3823635 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29110150 — Surrogate Endpoint (SUR): Blood pressure
Study 11919119 — Surrogate Endpoint (SUR): Blood pressure
Study 10232685 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29908832 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31907125 — Surrogate Endpoint (SUR): Blood pressure
Study 31907125 — Surrogate Endpoint (SUR): Bone mineral density
Study 10682110 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 2283647 — Surrogate Endpoint (SUR): Blood pressure
Study 218427 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 218427 — Surrogate Endpoint (SUR): Blood pressure
Study 24523431 — Surrogate Endpoint (SUR): Blood pressure
Study 24523431 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23896377 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 17675341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12202092 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 9832115 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21636183 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18175066 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 17205814 — Surrogate Endpoint (SUR): Serum creatinine
Study 29228147 — Surrogate Endpoint (SUR): Blood pressure
Study 26247967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26247967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26247967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24284085 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 17611715 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 16553681 — Surrogate Endpoint (SUR): Blood pressure
Study 14610097 — Surrogate Endpoint (SUR): Blood pressure
Study 27380647 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 30904691 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 26667034 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 24767620 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18046973 — Surrogate Endpoint (SUR): Blood pressure
Study 18046973 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12522468 — Surrogate Endpoint (SUR): Blood pressure
Study 20560910 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16928710 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9933750 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 2186867 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2186867 — Surrogate Endpoint (SUR): Blood pressure
Study 25887344 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 15589857 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15589857 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15589857 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15589857 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11320497 — Surrogate Endpoint (SUR): Blood pressure
Study 25673568 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 25673568 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 16316966 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 28265180 — Surrogate Endpoint (SUR): Blood pressure
Study 25112009 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19618315 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 19618315 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 19618315 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 19332730 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19332730 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19332730 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12106935 — Surrogate Endpoint (SUR): Serum creatinine
Study 2206783 — Surrogate Endpoint (SUR): Blood pressure
Study 31930892 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19950091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19950091 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17323226 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 15310081 — Surrogate Endpoint (SUR): Blood pressure
Study 28650919 — Surrogate Endpoint (SUR): Blood pressure
Study 11164425 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 11164425 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9342067 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9342067 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2870732 — Surrogate Endpoint (SUR): Blood pressure
Study 20860413 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20860413 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18090355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18090355 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10950768 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18931219 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 9203934 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29766330 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25359435 — Predictive Biomarker (PRD): SP2 mRNA
Genes: SP2; KIAA0048
Study 22735801 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 6400110 — Surrogate Endpoint (SUR): Blood pressure
Study 28622463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28622463 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8275438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8275438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8275438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8275438 — Safety Biomarker (SAF): Interleukin 1
Study 30664549 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 30664549 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 30664549 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 17067136 — Surrogate Endpoint (SUR): Blood pressure
Study 17067136 — Surrogate Endpoint (SUR): Serum potassium
Study 8551420 — Surrogate Endpoint (SUR): Serum sodium
Study 30132262 — Surrogate Endpoint (SUR): Blood pressure
Study 30132262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28471773 — Surrogate Endpoint (SUR): Blood pressure
Study 19000552 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11187921 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 11187921 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18226670 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31879229 — Surrogate Endpoint (SUR): Sperm parameters
Study 27382456 — Surrogate Endpoint (SUR): Blood pressure
Study 24802951 — Safety Biomarker (SAF): IL-6 and IL-10
Study 30661700 — Surrogate Endpoint (SUR): Blood pressure
Study 24055350 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23327034 — Surrogate Endpoint (SUR): Blood pressure
Study 18806966 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23218453 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11544618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27716201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18031594 — Surrogate Endpoint (SUR): Bone mineral density
Study 19409854 — Surrogate Endpoint (SUR): Bone mineral density
Study 26490434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 9275134 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28814805 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28814805 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16987866 — Monitoring Biomarker (MOI): HBV DNA
Study 25961461 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25961461 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 12581972 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2258780 — Surrogate Endpoint (SUR): Blood pressure
Study 20950166 — Surrogate Endpoint (SUR): Bone mineral density
Study 14616834 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 14616834 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 6184564 — Surrogate Endpoint (SUR): Blood pressure
Study 26031399 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 15083370 — Surrogate Endpoint (SUR): Plasma ammonia
Study 11435508 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 11435508 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 11435508 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11435508 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11271223 — Surrogate Endpoint (SUR): Blood pressure
Study 21215482 — Surrogate Endpoint (SUR): Blood pressure
Study 22588495 — Surrogate Endpoint (SUR): Blood pressure
Study 17591527 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17591527 — Surrogate Endpoint (SUR): Blood pressure
Study 17591527 — Surrogate Endpoint (SUR): Serum creatinine
Study 16318141 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 12175313 — Surrogate Endpoint (SUR): Blood pressure
Study 8595506 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27270841 — Surrogate Endpoint (SUR): Blood pressure
Study 22929458 — Surrogate Endpoint (SUR): Blood pressure
Study 22929458 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12665974 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1530141 — Surrogate Endpoint (SUR): Blood pressure
Study 26571136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26571136 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18675745 — Surrogate Endpoint (SUR): Blood pressure
Study 10634391 — Surrogate Endpoint (SUR): Blood pressure
Study 1610161 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31103608 — Predictive Biomarker (PRD): PAPPA mRNA
Genes: PAPPA
Study 31103608 — Predictive Biomarker (PRD): PAPPA2 mRNA
Genes: PAPPA2; PLAC3
Study 3131794 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15315998 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 15315998 — Surrogate Endpoint (SUR): Bone mineral density
Study 30810638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24279801 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12808175 — Surrogate Endpoint (SUR): Blood pressure
Study 10492157 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8697718 — Surrogate Endpoint (SUR): Blood pressure
Study 20039889 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16258155 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30201024 — Surrogate Endpoint (SUR): Bone mineral density
Study 25453515 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29068977 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 19486654 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9829706 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 27670267 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 23701492 — Safety Biomarker (SAF): Reactive oxygen species
Study 19056550 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 15383083 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31144547 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29337906 — Surrogate Endpoint (SUR): Bone mineral density
Study 22607134 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16219883 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28138133 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 25968249 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 11465636 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11465636 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30902613 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study 30902613 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 22000927 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15486846 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8873668 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 24890531 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18551008 — Surrogate Endpoint (SUR): Blood pressure
Study 31714586 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31714586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31714586 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 31270967 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22297674 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22297674 — Surrogate Endpoint (SUR): Serum calcium
Study 9927810 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 25560821 — Surrogate Endpoint (SUR): Blood pressure
Study 17109365 — Surrogate Endpoint (SUR): Blood pressure
Study 2939216 — Surrogate Endpoint (SUR): Blood pressure
Study 24442226 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17519080 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26123096 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 26123096 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 19927141 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10846637 — Surrogate Endpoint (SUR): Blood pressure
Study 8198040 — Surrogate Endpoint (SUR): Blood pressure
Study 29704228 — Pharmacodynamic Biomarker (PDY): GATA-type zinc finger protein 1
Genes: ZGLP1; GLP1
Study 29704228 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 29704228 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 18454096 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 16816661 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28038680 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 24998644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24998644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19256282 — Surrogate Endpoint (SUR): Blood pressure
Study 15955629 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study 12702130 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10233027 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 19542207 — Safety Biomarker (SAF): Interleukin 1
Study 19542207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2768706 — Surrogate Endpoint (SUR): Blood pressure
Study 2768706 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2768706 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19138610 — Safety Biomarker (SAF): Hyaluronic acid
Study 27096358 — Surrogate Endpoint (SUR): Blood pressure
Study 23895132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23895132 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23895132 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23895132 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 6256423 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31311386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29879249 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 7988250 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 7988250 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16792584 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 10479132 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10479132 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10479132 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10479132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1937663 — Surrogate Endpoint (SUR): Blood pressure
Study 6289857 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6289857 — Surrogate Endpoint (SUR): Blood pressure
Study 24372004 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 28331003 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28331003 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 10980901 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20719727 — Surrogate Endpoint (SUR): Blood pressure
Study 18812884 — Surrogate Endpoint (SUR): Blood pressure
Study 15909491 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 11783197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8609343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8609343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18725484 — Surrogate Endpoint (SUR): Blood pressure
Study 8859726 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 8859726 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8859726 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 8859726 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8859726 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30605922 — Predictive Biomarker (PRD): TXN mRNA
Genes: TXN; TRDX; TRX; TRX1
Study 16209965 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 1409873 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30031679 — Predictive Biomarker (PRD): SPX mRNA
Genes: SPX; C12orf39
Study 26873871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26873871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24571754 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18519845 — Surrogate Endpoint (SUR): Blood pressure
Study 18519845 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1971472 — Surrogate Endpoint (SUR): Blood pressure
Study 11136260 — Surrogate Endpoint (SUR): Bone mineral density
Study 1449922 — Surrogate Endpoint (SUR): Blood pressure
Study 23044303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24971340 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 20176498 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10211628 — Predictive Biomarker (PRD): ALAD mRNA
Genes: ALAD
Study 7744517 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28931220 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 28931220 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 23380105 — Pharmacodynamic Biomarker (PDY): Valproic acid