TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31222434 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 25118055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25118055 — Surrogate Endpoint (SUR): Blood pressure
Study 19614805 — Surrogate Endpoint (SUR): Blood pressure
Study 12473876 — Surrogate Endpoint (SUR): Blood pressure
Study 2366542 — Surrogate Endpoint (SUR): Blood pressure
Study 31787055 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 27136962 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 27136962 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 15974642 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15974642 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15974642 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 15974642 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30810754 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23514733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19575143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19575143 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 19575143 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16466554 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 29273207 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 28329061 — Monitoring Biomarker (MOI): HBV DNA
Study 26161399 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26161399 — Surrogate Endpoint (SUR): Blood pressure
Study 21215350 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 9364996 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3087241 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29356602 — Surrogate Endpoint (SUR): Blood pressure
Study 12679832 — Surrogate Endpoint (SUR): Bone mineral density
Study 20040336 — Predictive Biomarker (PRD): ABCB4 mRNA
Genes: ABCB4; MDR3; PGY3
Study 15738932 — Surrogate Endpoint (SUR): Blood pressure
Study 12627305 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18344178 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 2364508 — Surrogate Endpoint (SUR): Blood pressure
Study 26040978 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15975182 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21975293 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 20152212 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12638326 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10226901 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7042502 — Surrogate Endpoint (SUR): Blood pressure
Study 23897015 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21991942 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30265153 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27216329 — Predictive Biomarker (PRD): OSR1 mRNA
Genes: OSR1; ODD
Study 17984668 — Surrogate Endpoint (SUR): Blood pressure
Study 12390317 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 12390317 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 12390317 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 12390317 — Safety Biomarker (SAF): IL16
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 12390317 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 7847530 — Surrogate Endpoint (SUR): Blood pressure
Study 25877498 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 15015438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31823130 — Surrogate Endpoint (SUR): Serum uric acid
Study 28930490 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 29061183 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29061183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21263414 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 18823530 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 18823530 — Predictive Biomarker (PRD): FADD mRNA
Genes: FADD; MORT1; GIG3
Study 18823530 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 2854738 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29483842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 22374696 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 24633272 — Surrogate Endpoint (SUR): Serum creatinine
Study 19748665 — Surrogate Endpoint (SUR): Blood pressure
Study 7742677 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7742677 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24746829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24746829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24746829 — Surrogate Endpoint (SUR): Blood pressure
Study 15738536 — Surrogate Endpoint (SUR): Serum creatinine
Study 12118902 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19837764 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 11733394 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 2886716 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12893197 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 8947448 — Surrogate Endpoint (SUR): Blood pressure
Study 8947448 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31512717 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20951986 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 27149365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27149365 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27149365 — Safety Biomarker (SAF): Hyaluronic acid
Study 15834327 — Surrogate Endpoint (SUR): Blood pressure
Study 10561813 — Surrogate Endpoint (SUR): Blood pressure
Study 8722432 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19104360 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 12500172 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 3768242 — Surrogate Endpoint (SUR): Blood pressure
Study 30916381 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 11755507 — Surrogate Endpoint (SUR): Blood pressure
Study 26743539 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 26743539 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 26743539 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26743539 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11428735 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9870877 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 9870877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8746831 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 8746831 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2184355 — Surrogate Endpoint (SUR): Blood pressure
Study 30621702 — Predictive Biomarker (PRD): LIPG mRNA
Genes: LIPG; UNQ387/PRO719
Study 30621702 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30621702 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25787997 — Surrogate Endpoint (SUR): Blood pressure
Study 18001201 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 23831920 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 15494466 — Surrogate Endpoint (SUR): Bone mineral density
Study 9155120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30872203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30872203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30872203 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27767387 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 9466099 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 21717444 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31130260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29234808 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7986398 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26599634 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 23181592 — Surrogate Endpoint (SUR): Blood pressure
Study 22152013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22152013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9438889 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9438889 — Surrogate Endpoint (SUR): Blood pressure
Study 7705775 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 7705775 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11712091 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 8703810 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22089179 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22089179 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22089179 — Surrogate Endpoint (SUR): Blood pressure
Study 21429719 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21429719 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 2651329 — Surrogate Endpoint (SUR): Blood pressure
Study 28665989 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 19473635 — Surrogate Endpoint (SUR): Serum calcium
Study 9028089 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8500234 — Surrogate Endpoint (SUR): Blood pressure
Study 29110281 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 19865092 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19865092 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18262390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18262390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18262390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16169354 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24387700 — Surrogate Endpoint (SUR): Blood pressure
Study 18420395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16110022 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 16110022 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 16110022 — Predictive Biomarker (PRD): Microsatellite instability
Study 12852722 — Surrogate Endpoint (SUR): Blood pressure
Study 12852722 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7465712 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27567635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18000962 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 15521899 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11134196 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28229548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28229548 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28229548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24338654 — Surrogate Endpoint (SUR): Blood pressure
Study 24338654 — Surrogate Endpoint (SUR): Serum sodium
Study 24338654 — Surrogate Endpoint (SUR): Serum potassium
Study 17600040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12473255 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25845223 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25845223 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25845223 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11641307 — Surrogate Endpoint (SUR): Blood pressure
Study 26546883 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 26546883 — Surrogate Endpoint (SUR): Blood pressure
Study 26546883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19233758 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9585275 — Surrogate Endpoint (SUR): Blood pressure
Study 25161696 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22197630 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 22197630 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 25510692 — Safety Biomarker (SAF): Reactive oxygen species
Study 17211576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9715782 — Surrogate Endpoint (SUR): Blood pressure
Study 9715782 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3066086 — Surrogate Endpoint (SUR): Blood pressure
Study 30837426 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 30837426 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30837426 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10577849 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10577849 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31286729 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 31286729 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16166239 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16166239 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 16166239 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9086380 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 7690165 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27412590 — Surrogate Endpoint (SUR): Blood pressure
Study 27412590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20339966 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20339966 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 20339966 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8809913 — Surrogate Endpoint (SUR): Blood pressure
Study 1534715 — Surrogate Endpoint (SUR): Blood pressure
Study 24930625 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10067001 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 29306475 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 20545208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20545208 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9602961 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27786578 — Surrogate Endpoint (SUR): Blood pressure
Study 7662226 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7662226 — Surrogate Endpoint (SUR): Blood pressure
Study 30569761 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 28209488 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 26468834 — Surrogate Endpoint (SUR): Bone mineral density
Study 17048062 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 17048062 — Surrogate Endpoint (SUR): Bone mineral density
Study 12025949 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7809577 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27982270 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25529060 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 15834928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15834928 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 7795834 — Surrogate Endpoint (SUR): Blood pressure
Study 31277537 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 31277537 — Surrogate Endpoint (SUR): Bone mineral density
Study 28378600 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23477707 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19089532 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 17200777 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 6841923 — Surrogate Endpoint (SUR): Blood pressure
Study 29491276 — Safety Biomarker (SAF): Reactive oxygen species
Study 24962549 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24962549 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 1792811 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 1792811 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 29772277 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29772277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29772277 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29772277 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 29772277 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 29772277 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 29772277 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 24313663 — Surrogate Endpoint (SUR): Blood pressure
Study 19279518 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 19279518 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 19279518 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17704416 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17704416 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7848623 — Surrogate Endpoint (SUR): Blood pressure
Study 3535933 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24836309 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18842795 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18842795 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18842795 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18842795 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18842795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28750640 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28750640 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28750640 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28750640 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 28750640 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 28750640 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 28750640 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 23432535 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 19964700 — Surrogate Endpoint (SUR): Blood pressure
Study 17216322 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17216322 — Surrogate Endpoint (SUR): Blood pressure
Study 11378836 — Surrogate Endpoint (SUR): Blood pressure
Study 28763548 — Surrogate Endpoint (SUR): Blood pressure
Study 18219451 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 30654298 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 11339443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30572991 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 24997853 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1