TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8771109 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28916304 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 18514906 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18514906 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12669270 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15754237 — Surrogate Endpoint (SUR): Blood pressure
Study 28658126 — Surrogate Endpoint (SUR): Blood pressure
Study 15379416 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15379416 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15379416 — Surrogate Endpoint (SUR): Blood pressure
Study 16924985 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 15631892 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 15631892 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15631892 — Monitoring Biomarker (MOI): Complement C4
Study 10092996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10092996 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10092996 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor delta
Genes: PPARD
Study 31568675 — Predictive Biomarker (PRD): AKR1C3 mRNA
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 31568675 — Predictive Biomarker (PRD): 40S ribosomal protein S6
Genes: RPS6; OK/SW-cl.2
Study 31568675 — Surrogate Endpoint (SUR): Serum testosterone
Study 25189222 — Monitoring Biomarker (MOI): Procalcitonin
Study 25851052 — Monitoring Biomarker (MOI): HBV DNA
Study 20400652 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20067974 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15325831 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 9605982 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 30592963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16131698 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16131698 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16131698 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17702654 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17561350 — Predictive Biomarker (PRD): Hormone receptor
Study 9654535 — Monitoring Biomarker (MOI): HBV DNA
Study 30589514 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 28752209 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28752209 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28752209 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9283534 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30587618 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28862770 — Safety Biomarker (SAF): Hyaluronic acid
Study 16166818 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22375890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20584695 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10395842 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10395842 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29609113 — Safety Biomarker (SAF): Reactive oxygen species
Study 20504911 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 20504911 — Surrogate Endpoint (SUR): Blood pressure
Study 12003176 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12003176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22245162 — Surrogate Endpoint (SUR): Blood pressure
Study 22245162 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10379016 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30728339 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18004131 — Surrogate Endpoint (SUR): Blood pressure
Study 10202741 — Surrogate Endpoint (SUR): Serum calcium
Study 25922302 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23350696 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study 19629292 — Surrogate Endpoint (SUR): Blood pressure
Study 11511435 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9612361 — Surrogate Endpoint (SUR): Blood pressure
Study 30929275 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 28960230 — Surrogate Endpoint (SUR): Bone mineral density
Study 25583412 — Surrogate Endpoint (SUR): Blood pressure
Study 26186566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26186566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19247655 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 15316165 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 3838401 — Surrogate Endpoint (SUR): Blood pressure
Study 31612309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31612309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31612309 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29969520 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 29969520 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27287235 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29056008 — Monitoring Biomarker (MOI): HBV DNA
Study 23809140 — Surrogate Endpoint (SUR): Bone mineral density
Study 15486377 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8320604 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22234020 — Surrogate Endpoint (SUR): Blood pressure
Study 17585031 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 17585031 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 9024174 — Surrogate Endpoint (SUR): Blood pressure
Study 8843231 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10394407 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8871870 — Monitoring Biomarker (MOI): HBV DNA
Study 10585796 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29959901 — Surrogate Endpoint (SUR): Bone mineral density
Study 23789215 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11015169 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2580182 — Surrogate Endpoint (SUR): Blood pressure
Study 30046837 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30046837 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18562739 — Surrogate Endpoint (SUR): Serum creatinine
Study 386913 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 26967821 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 11889011 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10077394 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10077394 — Surrogate Endpoint (SUR): Serum creatinine
Study 31284844 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25825410 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25825410 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24642379 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22786569 — Surrogate Endpoint (SUR): Blood pressure
Study 22786569 — Surrogate Endpoint (SUR): Serum potassium
Study 20012639 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12399289 — Surrogate Endpoint (SUR): Blood pressure
Study 7477218 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2155751 — Surrogate Endpoint (SUR): Serum calcium
Study 7250475 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27692491 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 16281465 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1382217 — Surrogate Endpoint (SUR): Blood pressure
Study 3003305 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27848017 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 11351935 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 29549523 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28207287 — Surrogate Endpoint (SUR): Serum creatinine
Study 25867422 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21036772 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21036772 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10863716 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24709712 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 24709712 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 22416821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22416821 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22416821 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9380238 — Surrogate Endpoint (SUR): Serum calcium
Study 29874654 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29874654 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 29874654 — Surrogate Endpoint (SUR): Serum calcium
Study 29874654 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 12652226 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 2111249 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7457415 — Surrogate Endpoint (SUR): Blood pressure
Study 16371019 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16371019 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 30971593 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30971593 — Surrogate Endpoint (SUR): Blood pressure
Study 11860948 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16384692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8857476 — Surrogate Endpoint (SUR): Serum creatinine
Study 1346790 — Surrogate Endpoint (SUR): Blood pressure
Study 31662555 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 15037536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15037536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15037536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26797134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26797134 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 15568599 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30672212 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30672212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27336903 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27336903 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24398786 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 17902730 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 16234763 — Surrogate Endpoint (SUR): Blood pressure
Study 7771420 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9972406 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3130890 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 26239735 — Surrogate Endpoint (SUR): Serum creatinine
Study 18579392 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 10819253 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 8894262 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8894262 — Surrogate Endpoint (SUR): Blood pressure
Study 25540062 — Surrogate Endpoint (SUR): Blood pressure
Study 17469162 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 11252048 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8277200 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 2470865 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 23154592 — Surrogate Endpoint (SUR): Blood pressure
Study 12671885 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 2574496 — Surrogate Endpoint (SUR): Serum potassium
Study 23627460 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21932567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21932567 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19304668 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19304668 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11738278 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11738278 — Surrogate Endpoint (SUR): Blood pressure
Study 11738278 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10481384 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 10481384 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10481384 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29267221 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29267221 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24359313 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 16085504 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 27001425 — Surrogate Endpoint (SUR): Blood pressure
Study 22739396 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16950591 — Surrogate Endpoint (SUR): Blood pressure
Study 15616079 — Surrogate Endpoint (SUR): Blood pressure
Study 31259883 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 31259883 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 22855599 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 22855599 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 22855599 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 19470925 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19470925 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 19470925 — Predictive Biomarker (PRD): NR1I2 mRNA
Genes: NR1I2; PXR
Study 19470925 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 19470925 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 19470925 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 27940458 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20454974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20454974 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 18410952 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18410952 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 6649055 — Surrogate Endpoint (SUR): Blood pressure
Study 29880546 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29880546 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29880546 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20435865 — Surrogate Endpoint (SUR): Blood pressure
Study 27513155 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8868037 — Surrogate Endpoint (SUR): Blood pressure
Study 1380024 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22178576 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 2882775 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31060632 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 27363506 — Predictive Biomarker (PRD): SCN9A mRNA
Genes: SCN9A; NENA
Study 24786948 — Predictive Biomarker (PRD): GRIK1 mRNA
Genes: GRIK1; GLUR5
Study 16390023 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 11207836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11207836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12486429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9798037 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30763599 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 26884439 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 26884439 — Predictive Biomarker (PRD): PNPLA2 mRNA
Genes: PNPLA2; ATGL; FP17548
Study 26884439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26884439 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25526951 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 19196819 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19196819 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16335699 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16335699 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11740718 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25839137 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 24206457 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2441156 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31137991 — Surrogate Endpoint (SUR): Blood pressure
Study 28557655 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 28557655 — Safety Biomarker (SAF): Hyaluronic acid
Study 17100757 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9383502 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 23075398 — Surrogate Endpoint (SUR): Blood pressure
Study 16300696 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8554498 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31453982 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 24755888 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 14990394 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9064950 — Surrogate Endpoint (SUR): Blood pressure
Study 1473306 — Surrogate Endpoint (SUR): Blood pressure
Study 26561047 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 24451613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15465887 — Surrogate Endpoint (SUR): Blood pressure
Study 8072815 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 15779502 — Surrogate Endpoint (SUR): Blood pressure
Study 25794163 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25794163 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 25794163 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 11930695 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 11930695 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 2853091 — Surrogate Endpoint (SUR): Blood pressure
Study 29880292 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29880292 — Surrogate Endpoint (SUR): Pathological complete response
Study 29880292 — Predictive Biomarker (PRD): Hormone receptor
Study 24200275 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 21169471 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17196057 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 17196057 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17196057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17196057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8957034 — Surrogate Endpoint (SUR): Blood pressure
Study 8957034 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22446739 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 25351652 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23669281 — Monitoring Biomarker (MOI): HBV DNA
Study 17971666 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 30426166 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28796888 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7625114 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7625114 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31464642 — Surrogate Endpoint (SUR): Bone mineral density
Study 20170948 — Surrogate Endpoint (SUR): Blood pressure
Study 20170948 — Surrogate Endpoint (SUR): Serum creatinine
Study 12200762 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12200762 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25110231 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 18068514 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 18068514 — Surrogate Endpoint (SUR): Blood pressure
Study 18068514 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18068514 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 916947 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS