TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30648524 — Predictive Biomarker (PRD): WNT16 mRNA
Genes: WNT16
Study 30648524 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 30648524 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 30576794 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 22250063 — Surrogate Endpoint (SUR): Blood pressure
Study 17284910 — Surrogate Endpoint (SUR): Bacterial count
Study 28224232 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 28224232 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 28224232 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 28224232 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 799551 — Surrogate Endpoint (SUR): Blood pressure
Study 25474080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15136071 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 2830189 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2830189 — Surrogate Endpoint (SUR): Blood pressure
Study 30963177 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 23491407 — Predictive Biomarker (PRD): NIBAN1 mRNA
Genes: NIBAN1; C1orf24; FAM129A; NIBAN; GIG39
Study 23491407 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SYNPO2 mRNA
Genes: SYNPO2
Study 20153492 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 9220217 — Surrogate Endpoint (SUR): Blood pressure
Study 9220217 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9220217 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25074756 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25074756 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23089925 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23089925 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18398079 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 21067347 — Surrogate Endpoint (SUR): Blood pressure
Study 10820175 — Safety Biomarker (SAF): MTHFR
Study 1514338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29943100 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11980869 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6982270 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31192515 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 26950019 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 26878318 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25392505 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 17980044 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 8562236 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30605396 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30605396 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30605396 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 21317789 — Surrogate Endpoint (SUR): Blood pressure
Study 14665887 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 25364081 — Surrogate Endpoint (SUR): Blood pressure
Study 19140845 — Surrogate Endpoint (SUR): Blood pressure
Study 17717439 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 17592908 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 9342601 — Surrogate Endpoint (SUR): Blood pressure
Study 8518523 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 2545640 — Surrogate Endpoint (SUR): Blood pressure
Study 30973001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30973001 — Monitoring Biomarker (MOI): Procalcitonin
Study 30973001 — Surrogate Endpoint (SUR): Serum creatinine
Study 29025845 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22939927 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 19863177 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 6402075 — Surrogate Endpoint (SUR): Blood pressure
Study 19112278 — Surrogate Endpoint (SUR): Serum creatinine
Study 19112278 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 17309328 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 15517671 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8056006 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28681366 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 21455728 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 16507605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12601267 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7683800 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 26573041 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 23840403 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23840403 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 23840403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23840403 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23840403 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16493496 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16493496 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 10211848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8874330 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17076775 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 11504824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11504824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9116394 — Surrogate Endpoint (SUR): Bone mineral density
Study 6657002 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23429593 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14505296 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 22184366 — Surrogate Endpoint (SUR): Bone mineral density
Study 16277783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16277783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2110972 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21514017 — Surrogate Endpoint (SUR): Blood pressure
Study 12145008 — Surrogate Endpoint (SUR): Blood pressure
Study 2110336 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 382381 — Surrogate Endpoint (SUR): Blood pressure
Study 29284183 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 29284183 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 26867046 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12752488 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10218722 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29273007 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 26333499 — Surrogate Endpoint (SUR): Blood pressure
Study 11297596 — Surrogate Endpoint (SUR): Blood pressure
Study 31606265 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 31651370 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24052362 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24052362 — Surrogate Endpoint (SUR): Blood pressure
Study 7535990 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 7535990 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30662331 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 23711188 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21850387 — Safety Biomarker (SAF): Hyaluronic acid
Study 12191965 — Surrogate Endpoint (SUR): Serum creatinine
Study 12191965 — Surrogate Endpoint (SUR): Serum uric acid
Study 19917367 — Surrogate Endpoint (SUR): Serum creatinine
Study 15049991 — Surrogate Endpoint (SUR): Serum testosterone
Study 21786177 — Surrogate Endpoint (SUR): Blood pressure
Study 18609080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18609080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18609080 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16869719 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 2142633 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1420010 — Surrogate Endpoint (SUR): Blood pressure
Study 15946834 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10344294 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8559498 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26717057 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26717057 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 8740302 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 8740302 — Surrogate Endpoint (SUR): Plasma ammonia
Study 26721259 — Surrogate Endpoint (SUR): Blood pressure
Study 12139647 — Surrogate Endpoint (SUR): Blood pressure
Study 8001304 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8001304 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8001304 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24288395 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 24288395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24288395 — Surrogate Endpoint (SUR): Blood pressure
Study 15289996 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 10442212 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24341511 — Surrogate Endpoint (SUR): Blood pressure
Study 24341511 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10950448 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9018408 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9018408 — Surrogate Endpoint (SUR): Serum testosterone
Study 22084404 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22084404 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18991094 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16466167 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study 16466167 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16466167 — Monitoring Biomarker (MOI): HBV DNA
Study 22081618 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22081618 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9663812 — Surrogate Endpoint (SUR): Blood pressure
Study 31652195 — Surrogate Endpoint (SUR): Blood pressure
Study 25280085 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 23459567 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 21831004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21831004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16871129 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 10952230 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 17233546 — Surrogate Endpoint (SUR): Bone mineral density
Study 15618034 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10458007 — Surrogate Endpoint (SUR): Blood pressure
Study 28854085 — Surrogate Endpoint (SUR): Serum creatinine
Study 25925203 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16446400 — Surrogate Endpoint (SUR): Blood pressure
Study 10598608 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23813620 — Surrogate Endpoint (SUR): Blood pressure
Study 8101550 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29502373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28582403 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28582403 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 28582403 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 28582403 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 19386814 — Surrogate Endpoint (SUR): Blood pressure
Study 11157316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18795972 — Surrogate Endpoint (SUR): Blood pressure
Study 10437215 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 30549489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30549489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24703391 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 24703391 — Safety Biomarker (SAF): Hyaluronic acid
Study 28315568 — Surrogate Endpoint (SUR): Blood pressure
Study 30839100 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 24474034 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7523775 — Surrogate Endpoint (SUR): Blood pressure
Study 30694699 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 20473047 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 11049910 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 11049910 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2485273 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 21196441 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 7636641 — Surrogate Endpoint (SUR): Blood pressure
Study 336116 — Predictive Biomarker (PRD): CLYBL mRNA
Genes: CLYBL; CLB
Study 27633965 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 3925888 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 23245621 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23245621 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 17672828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11000340 — Surrogate Endpoint (SUR): Bone mineral density
Study 1363497 — Surrogate Endpoint (SUR): Blood pressure
Study 2877644 — Surrogate Endpoint (SUR): Blood pressure
Study 31362691 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28152655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28152655 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 26081016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26081016 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26081016 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26081016 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 12743862 — Surrogate Endpoint (SUR): Blood pressure
Study 1486738 — Surrogate Endpoint (SUR): Bone mineral density
Study 1486738 — Surrogate Endpoint (SUR): Serum calcium
Study 8273728 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9236672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28111123 — Surrogate Endpoint (SUR): Bone mineral density
Study 18216286 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study 26030111 — Surrogate Endpoint (SUR): Blood pressure
Study 28759347 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21270442 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 19581801 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 17132720 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 17132720 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15529604 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23677131 — Surrogate Endpoint (SUR): Blood pressure
Study 19302259 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 19302259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19302259 — Surrogate Endpoint (SUR): Blood pressure
Study 19302259 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19302259 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17507344 — Surrogate Endpoint (SUR): Blood pressure
Study 9271287 — Surrogate Endpoint (SUR): Bone mineral density
Study 15048662 — Predictive Biomarker (PRD): HTR2C mRNA
Genes: HTR2C; HTR1C
Study 9566644 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9566644 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2457767 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28419890 — Predictive Biomarker (PRD): CTSA mRNA
Genes: CTSA; PPGB
Study 18341680 — Surrogate Endpoint (SUR): Blood pressure
Study 26092649 — Surrogate Endpoint (SUR): Bone mineral density
Study 27935977 — Surrogate Endpoint (SUR): Blood pressure
Study 22606978 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 20091824 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10523008 — Surrogate Endpoint (SUR): Serum testosterone
Study 10523008 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1773906 — Surrogate Endpoint (SUR): Blood pressure
Study 21162796 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14996521 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10434216 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 10434216 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10434216 — Surrogate Endpoint (SUR): Blood pressure
Study 7822519 — Surrogate Endpoint (SUR): Serum calcium
Study 30905721 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 30905721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25312997 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 21278620 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 21278620 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 21278620 — Surrogate Endpoint (SUR): Blood pressure
Study 20141097 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31976576 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 20003316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20003316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17314918 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 30770424 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22041889 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 7957504 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31335759 — Surrogate Endpoint (SUR): Blood pressure
Study 24517057 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16704296 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16704296 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11523315 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11523315 — Surrogate Endpoint (SUR): Blood pressure
Study 8539545 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 25033263 — Surrogate Endpoint (SUR): Blood pressure
Study 15636426 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11791121 — Predictive Biomarker (PRD): Hormone receptor
Study 7953984 — Surrogate Endpoint (SUR): Bone mineral density
Study 22586212 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 22586212 — Surrogate Endpoint (SUR): Blood pressure
Study 15947713 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 15947713 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1691406 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28676443 — Surrogate Endpoint (SUR): Blood pressure
Study 30089732 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 30089732 — Predictive Biomarker (PRD): TMEM26 mRNA
Genes: TMEM26
Study 30089732 — Predictive Biomarker (PRD): CIDEA mRNA
Genes: CIDEA
Study 27282232 — Surrogate Endpoint (SUR): Blood pressure
Study 15784718 — Surrogate Endpoint (SUR): Blood pressure
Study 7955757 — Predictive Biomarker (PRD): CEACAM6 mRNA
Genes: CEACAM6; NCA
Study 23239151 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21605022 — Surrogate Endpoint (SUR): Serum creatinine
Study 9663369 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9663369 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol