TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03258801 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01340482 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02977065 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT01091428 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT03732703 — Predictive Biomarker (PRD): CDKN2C mRNA
Genes: CDKN2C; CDKN6
Study NCT03732703 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT03732703 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03732703 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT03732703 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT04019600 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02247999 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT02167165 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT02167165 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study NCT02167165 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study NCT01360970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02946359 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02946359 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02946359 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT00542659 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT00542659 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT00542659 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study NCT00542659 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study NCT00542659 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study NCT02404051 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02404051 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01604889 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT01681368 — Predictive Biomarker (PRD): DIABLO mRNA
Genes: DIABLO; SMAC
Study NCT03128034 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT01358877 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01945762 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01668433 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT02279004 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02279004 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00173628 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study NCT01702909 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03828955 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03828955 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01339949 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03685708 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00695682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04438096 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04438096 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05718349 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study NCT01007552 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04281485 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02521363 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06311383 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT06311383 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00478608 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study NCT01675102 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02284633 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02284633 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02679053 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02679053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02679053 — Safety Biomarker (SAF): BDNF
Study NCT01400464 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT02651285 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00600743 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT01790204 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01247116 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03982485 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT03982485 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03794141 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT03851874 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT02202486 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT02158624 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02763111 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT00588003 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01411319 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study NCT01411319 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT01551251 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study NCT02154932 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02332681 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00113698 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00219141 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01571960 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04584606 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02651870 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03093844 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02946879 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT01138319 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT01893112 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01439711 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00005023 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03550729 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01121640 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT01121640 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT00669747 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT01950299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01950299 — Safety Biomarker (SAF): Interleukin 1
Study NCT04060173 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03001947 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04436107 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01202305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00920764 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00920764 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00005501 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02241044 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT01107275 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01416246 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05034653 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04003090 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01589367 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02797704 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02871141 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00000513 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00952237 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00952237 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02361112 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02361112 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04348708 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00165594 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00760110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00039182 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03208309 — Safety Biomarker (SAF): Interleukin 1
Study NCT04301856 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04104633 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01149629 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05343637 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT05343637 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT05343637 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02762084 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study NCT00694525 — Predictive Biomarker (PRD): CYP21A2 mRNA
Genes: CYP21A2; CYP21; CYP21B
Study NCT00694525 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT00694525 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03597776 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02942953 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03908788 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03908788 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03312374 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01429467 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01429467 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02183415 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02961309 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT01874756 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01874756 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT01874756 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study NCT01876732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02631603 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04204252 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00311155 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00130507 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03933449 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00931138 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02653105 — Predictive Biomarker (PRD): OLFM4 mRNA
Genes: OLFM4; GW112; UNQ362/PRO698
Study NCT02653105 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01345643 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01173042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01173042 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT03650348 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04181190 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT01549665 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02804204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03637153 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04249947 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00921622 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01454544 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01286662 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT02728102 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04135820 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT00365495 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study NCT01436422 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02648880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02648880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02648880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02648880 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT04037384 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01887262 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02080520 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00005108 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03226457 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03226457 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03226457 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT03679013 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01960205 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03815773 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT00537030 — Surrogate Endpoint (SUR): Serum asparaginase
Study NCT00288873 — Surrogate Endpoint (SUR): Serum calcium
Study NCT03688789 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT03048110 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02793765 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03578848 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04070768 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT03821701 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02958579 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01981720 — Predictive Biomarker (PRD): PRX mRNA
Genes: PRX; KIAA1620
Study NCT02096120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01558674 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01762657 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03989713 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01874574 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03866408 — Predictive Biomarker (PRD): CIDEC mRNA
Genes: CIDEC; FSP27
Study NCT03866408 — Predictive Biomarker (PRD): PNPLA2 mRNA
Genes: PNPLA2; ATGL; FP17548
Study NCT03866408 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study NCT04656652 — Predictive Biomarker (PRD): TACSTD2 mRNA
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT02751528 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03776643 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00200499 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04643249 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT04643249 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT04643249 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT04643249 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04643249 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT04643249 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01117142 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02694614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02782741 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03308903 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT03546361 — Predictive Biomarker (PRD): CCL21 mRNA
Genes: CCL21; SCYA21; UNQ784/PRO1600
Study NCT02492217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03327675 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04326985 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01791595 — Predictive Biomarker (PRD): MCTS1 mRNA
Genes: MCTS1; MCT1
Study NCT01632332 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00039689 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02936102 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01676246 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study NCT02926963 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study NCT02926963 — Predictive Biomarker (PRD): CYBA mRNA
Genes: CYBA
Study NCT02926963 — Predictive Biomarker (PRD): NCF2 mRNA
Genes: NCF2; NOXA2; P67PHOX
Study NCT04149717 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04395768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02868437 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01626846 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00904241 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study NCT01048203 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study NCT02865564 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03947242 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01938547 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03390361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02434952 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT03608215 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00354367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01307280 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04201496 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03769844 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03769844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03025880 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03025880 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01221181 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT01221181 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01635361 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01862211 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT03911193 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02499328 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04309422 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03989089 — Predictive Biomarker (PRD): APOBEC3B mRNA
Genes: APOBEC3B
Study NCT04407962 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04407962 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02804945 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00941616 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04214418 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00663117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04426825 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04426825 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03033576 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02347449 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05110209 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05110209 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02935686 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04481139 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT03628859 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT00671346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04370821 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03325335 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01463774 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET