TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02369081 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06190457 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03612401 — Predictive Biomarker (PRD): NGB mRNA
Genes: NGB
Study NCT00552357 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT03700099 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02065544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03838588 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04313023 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04323371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04323371 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study NCT03034603 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT03034603 — Safety Biomarker (SAF): Cytochrome c
Study NCT01327755 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01155284 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT05163613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05163613 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01626222 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01626222 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04213404 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03526289 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02338570 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02338570 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study NCT02338570 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02747472 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01876329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02131857 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00333216 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03812809 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00877123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00877123 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT04788420 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00332709 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00127751 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00563147 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00591201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01823068 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01675297 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01436656 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT02557776 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02557776 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02634190 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01485614 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03646084 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00955773 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04426695 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01640574 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT04268823 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03790332 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01457781 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02868905 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study NCT02868905 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study NCT00211666 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02688647 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03532438 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT00534313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03841747 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03456726 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study NCT01245088 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT01150669 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00510653 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT00510653 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00254579 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01719211 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study NCT04015778 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04015778 — Predictive Biomarker (PRD): PDCD1LG2 mRNA
Genes: PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2
Study NCT02094768 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02094768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03798119 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00495040 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study NCT04514354 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00397332 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study NCT01576159 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT01972542 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04320030 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT02476734 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT00540618 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study NCT03751657 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00471549 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT01419379 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT00501228 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01602198 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT00970931 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03124173 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT02588352 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01710930 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study NCT04188496 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00545870 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00545870 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01717391 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01717391 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00781365 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01708031 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study NCT01960855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05234359 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03079440 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT03667170 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04254263 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04034199 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02932956 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT04625296 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03591770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01157117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03707457 — Predictive Biomarker (PRD): TNFRSF18 mRNA
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study NCT03707457 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT03492983 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01462474 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01462474 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01462474 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study NCT01462474 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03425708 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03689192 — Safety Biomarker (SAF): Arginase-1
Genes: ARG1
Study NCT01683552 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03020836 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03599375 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01301274 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01083758 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02556632 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT05601934 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01455974 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00807950 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT00807950 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study NCT00580333 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00580333 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00580333 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03543683 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03543683 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03706547 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03706547 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04405557 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03677414 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT04209218 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02002416 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02002416 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT04397250 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02964884 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01788813 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT01763164 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT03207139 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01338285 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04856579 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT03229395 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT03229395 — Predictive Biomarker (PRD): FSTL1 mRNA
Genes: FSTL1; FRP
Study NCT03609255 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03609255 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00888030 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05680311 — Predictive Biomarker (PRD): ENPP2 mRNA
Genes: ENPP2; ATX; PDNP2
Study NCT04630275 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02773784 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02773784 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02191215 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02965092 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02341937 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04209855 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT03391804 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT03080584 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00240292 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00240292 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00240292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00240292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03666351 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04522869 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02516722 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01400256 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00855010 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00199004 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00106132 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00134602 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00748657 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00212316 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00212316 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT06379022 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00659581 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03878433 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT02870322 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00646659 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01339858 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT01526876 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04344574 — Predictive Biomarker (PRD): IL33 mRNA
Genes: IL33; C9orf26; IL1F11; NFHEV
Study NCT04690387 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04262804 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01860729 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01860729 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00418080 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00418080 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04368182 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT02232269 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01424475 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT01608022 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01608022 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01608022 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02322853 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT03756493 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03756493 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study NCT03756493 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03283631 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03283631 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03946228 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02040025 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02691871 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02691871 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03054363 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03054363 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03054363 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01840657 — Predictive Biomarker (PRD): MTM1 mRNA
Genes: MTM1; CG2
Study NCT04727021 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01151683 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01678274 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01836809 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03888183 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03489746 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT03525782 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT02528422 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01688141 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02693652 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04338243 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00854412 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT01438333 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study NCT04438681 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03362242 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT03569020 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00316108 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04734678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04734678 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study NCT05386667 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT02626676 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT02626676 — Surrogate Endpoint (SUR): Serum phosphate
Study NCT03196375 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT01428115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01297777 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT03333915 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02612909 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01073462 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT02983279 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT02939131 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03438058 — Safety Biomarker (SAF): Human leucocyte antigen
Study NCT05217186 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT03166306 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03166306 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03723928 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00108108 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT00108108 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00979823 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02227940 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02464059 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT02091505 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01354132 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT01068444 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01068444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04458324 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00661518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04526821 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study NCT00289029 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03566056 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01436864 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04346290 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03754439 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT03690986 — Predictive Biomarker (PRD): SEMA4D mRNA
Genes: SEMA4D; C9orf164; CD100; SEMAJ
Study NCT03370770 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00403572 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04129840 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04641689 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04477876 — Predictive Biomarker (PRD): CD160 mRNA
Genes: CD160; BY55
Study NCT03984968 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02304926 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02304926 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02304926 — Safety Biomarker (SAF): Reactive oxygen species