TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26561615 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26561615 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21498063 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16551272 — Predictive Biomarker (PRD): ADCY10 mRNA
Genes: ADCY10; SAC
Study 12939717 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 3541501 — Predictive Biomarker (PRD): AIRE mRNA
Genes: AIRE; APECED
Study 1226582 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 16246962 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 7979623 — Surrogate Endpoint (SUR): Serum creatinine
Study 7979623 — Surrogate Endpoint (SUR): Serum potassium
Study 29448309 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 24761394 — Surrogate Endpoint (SUR): Forced vital capacity
Study 540455 — Surrogate Endpoint (SUR): Blood pressure
Study 31135053 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 23885143 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23885143 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12872340 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8730344 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8730344 — Surrogate Endpoint (SUR): Blood pressure
Study 8730344 — Surrogate Endpoint (SUR): Serum creatinine
Study 4054203 — Surrogate Endpoint (SUR): Blood pressure
Study 31728025 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24878327 — Predictive Biomarker (PRD): TKT mRNA
Genes: TKT
Study 11933903 — Predictive Biomarker (PRD): SRGN mRNA
Genes: SRGN; PRG; PRG1
Study 9806046 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29577365 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20849433 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15240596 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15240596 — Surrogate Endpoint (SUR): Blood pressure
Study 7987360 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 31849093 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 9697742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24838155 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20144258 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18396251 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 1732429 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1732429 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 6396239 — Surrogate Endpoint (SUR): Blood pressure
Study 6396239 — Surrogate Endpoint (SUR): Serum potassium
Study 29024599 — Surrogate Endpoint (SUR): Blood pressure
Study 24910546 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 24910546 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 20557927 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7795832 — Surrogate Endpoint (SUR): Blood pressure
Study 14749712 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9695216 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 9695216 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 9695216 — Surrogate Endpoint (SUR): Serum creatinine
Study 31342534 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 31342534 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 31342534 — Predictive Biomarker (PRD): HTR3A mRNA
Genes: HTR3A; 5HT3R; HTR3
Study 26915677 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 26915677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 26915677 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 26915677 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 19716238 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 15863638 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 25381136 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25381136 — Predictive Biomarker (PRD): Hormone receptor
Study 25381136 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21769734 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 18322990 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8730606 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21038652 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 21038652 — Surrogate Endpoint (SUR): Blood pressure
Study 12817904 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10423106 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27614801 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 27614801 — Surrogate Endpoint (SUR): Blood pressure
Study 10896253 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 6340504 — Surrogate Endpoint (SUR): Serum creatinine
Study 26429360 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17334829 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 12744870 — Predictive Biomarker (PRD): CLSTN2 mRNA
Genes: CLSTN2; CS2
Study 12744870 — Predictive Biomarker (PRD): CLSTN3 mRNA
Genes: CLSTN3; CS3; KIAA0726
Study 14693528 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28304211 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 21444874 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 21444874 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 2824706 — Surrogate Endpoint (SUR): Serum creatinine
Study 30990213 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30990213 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28847641 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21710343 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18473689 — Surrogate Endpoint (SUR): Blood pressure
Study 11139111 — Surrogate Endpoint (SUR): Blood pressure
Study 22961867 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 22961867 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1319732 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 26893135 — Surrogate Endpoint (SUR): Blood pressure
Study 20706632 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10341866 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 28859944 — Surrogate Endpoint (SUR): Blood pressure
Study 24051108 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15988805 — Pharmacodynamic Biomarker (PDY): Peripheral myelin protein 22
Genes: PMP22; GAS3
Study 9010611 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9010611 — Surrogate Endpoint (SUR): Blood pressure
Study 26953637 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 18061171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18061171 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18061171 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18061171 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 12464326 — Safety Biomarker (SAF): DRD2
Study 6342863 — Surrogate Endpoint (SUR): Blood pressure
Study 23946346 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8445420 — Predictive Biomarker (PRD): Hormone receptor
Study 26905433 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 26905433 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22235139 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study 1953259 — Surrogate Endpoint (SUR): Blood pressure
Study 17533024 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17533024 — Surrogate Endpoint (SUR): Serum calcium
Study 3535022 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 31865665 — Predictive Biomarker (PRD): SACS mRNA
Genes: SACS; KIAA0730
Study 22661489 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 19597646 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 15216462 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12512233 — Surrogate Endpoint (SUR): Blood pressure
Study 9586148 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 30543801 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 23275313 — Surrogate Endpoint (SUR): Blood pressure
Study 15185883 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7704289 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7704289 — Surrogate Endpoint (SUR): Blood pressure
Study 7704289 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3296721 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10594293 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 31189978 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26467358 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 19933083 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11096044 — Surrogate Endpoint (SUR): Blood pressure
Study 11096044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11096044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16674618 — Surrogate Endpoint (SUR): Blood pressure
Study 15080818 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 31724354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31724354 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 25049048 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 21029815 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8101903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22418699 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22418699 — Predictive Biomarker (PRD): Hormone receptor
Study 22418699 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15880062 — Surrogate Endpoint (SUR): Serum creatinine
Study 10100144 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8915032 — Safety Biomarker (SAF): Interleukin 1
Study 28273202 — Surrogate Endpoint (SUR): Blood pressure
Study 18614145 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 18614145 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20800376 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 1549934 — Surrogate Endpoint (SUR): Blood pressure
Study 31274545 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 23153344 — Surrogate Endpoint (SUR): Blood pressure
Study 20605441 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17921382 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15505638 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8696714 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 26545405 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24694986 — Surrogate Endpoint (SUR): Blood pressure
Study 24694986 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24694986 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22162050 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 9809692 — Surrogate Endpoint (SUR): Blood pressure
Study 30832198 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 30832198 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 28973024 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 28973024 — Predictive Biomarker (PRD): NR4A1 mRNA
Genes: NR4A1; GFRP1; HMR; NAK1
Study 25633573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25633573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25633573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25633573 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19585825 — Surrogate Endpoint (SUR): Blood pressure
Study 23811853 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 23811853 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 23811853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23811853 — Predictive Biomarker (PRD): FRK mRNA
Genes: FRK; PTK5; RAK
Study 23811853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23811853 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23811853 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28255655 — Safety Biomarker (SAF): Hyaluronic acid
Study 20837300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8061849 — Surrogate Endpoint (SUR): Blood pressure
Study 31158425 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 26132535 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 23048188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19221377 — Surrogate Endpoint (SUR): Blood pressure
Study 19221377 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29798206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14575277 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14575277 — Surrogate Endpoint (SUR): Blood pressure
Study 11004652 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 11004652 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 8713789 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1383574 — Surrogate Endpoint (SUR): Serum testosterone
Study 28702899 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 27093747 — Surrogate Endpoint (SUR): Blood pressure
Study 7607713 — Surrogate Endpoint (SUR): Blood pressure
Study 26266386 — Surrogate Endpoint (SUR): Blood pressure
Study 24057042 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16702318 — Surrogate Endpoint (SUR): Blood pressure
Study 1345038 — Surrogate Endpoint (SUR): Blood pressure
Study 21681921 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11294480 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 27148652 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 24684734 — Surrogate Endpoint (SUR): Blood pressure
Study 23557068 — Surrogate Endpoint (SUR): Blood pressure
Study 27016217 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 27016217 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16020461 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 9858113 — Surrogate Endpoint (SUR): Blood pressure
Study 31297652 — Surrogate Endpoint (SUR): Bone mineral density
Study 25129979 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 23715562 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15843667 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21474499 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19141981 — Predictive Biomarker (PRD): PIN1 mRNA
Genes: PIN1
Study 16189291 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16189291 — Surrogate Endpoint (SUR): Serum sodium
Study 31133472 — Surrogate Endpoint (SUR): Blood pressure
Study 23019948 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 20404423 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20404423 — Surrogate Endpoint (SUR): Serum creatinine
Study 20404423 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20404423 — Surrogate Endpoint (SUR): Blood pressure
Study 20404423 — Surrogate Endpoint (SUR): Serum potassium
Study 9785761 — Surrogate Endpoint (SUR): Bone mineral density
Study 27391857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27391857 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 2951826 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28231078 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28231078 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 28231078 — Surrogate Endpoint (SUR): Blood pressure
Study 18065202 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16253974 — Surrogate Endpoint (SUR): Bone mineral density
Study 1906239 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 24929624 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8550252 — Surrogate Endpoint (SUR): Serum testosterone
Study 6133104 — Surrogate Endpoint (SUR): Blood pressure
Study 30381311 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 29129600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17669707 — Surrogate Endpoint (SUR): Serum calcium
Study 11893781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11893781 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30948254 — Surrogate Endpoint (SUR): Blood pressure
Study 28257752 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 25981401 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25981401 — Surrogate Endpoint (SUR): Serum creatinine
Study 11323730 — Surrogate Endpoint (SUR): Blood pressure
Study 9468460 — Surrogate Endpoint (SUR): Blood pressure
Study 29174109 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21092137 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 29962050 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29962050 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24884501 — Predictive Biomarker (PRD): FCGR2A mRNA
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 24884501 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 24884501 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 15963119 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11393207 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29753374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29753374 — Surrogate Endpoint (SUR): Blood pressure
Study 27124410 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27124410 — Predictive Biomarker (PRD): Hormone receptor
Study 21360537 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 21360537 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21299684 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 14740177 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 24488582 — Predictive Biomarker (PRD): LYN mRNA
Genes: LYN; JTK8
Study 23082173 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24901128 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17015055 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 14523294 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27116921 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19512937 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19512937 — Surrogate Endpoint (SUR): Bone mineral density
Study 19512937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26398184 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 18054420 — Surrogate Endpoint (SUR): Blood pressure
Study 10996361 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 29133365 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25346026 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 19667500 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 1771401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30686103 — Surrogate Endpoint (SUR): Blood pressure
Study 30686103 — Surrogate Endpoint (SUR): Serum creatinine
Study 26881208 — Surrogate Endpoint (SUR): Bone mineral density
Study 22095057 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study 18047925 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18047925 — Surrogate Endpoint (SUR): Blood pressure
Study 12395333 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25641925 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 22092962 — Safety Biomarker (SAF): Hyaluronic acid
Study 7930726 — Predictive Biomarker (PRD): FCGR2A
Genes: CD32; CD32A; IGFR2; CDw32; Fc-gamma-RIIa; FcgammaRIIa
Study 6415735 — Surrogate Endpoint (SUR): Blood pressure
Study 20953746 — Safety Biomarker (SAF): Hyaluronic acid
Study 11296939 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 4776883 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 28293624 — Surrogate Endpoint (SUR): Blood pressure
Study 1438110 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3914805 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF