TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12768071 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11203592 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29737256 — Surrogate Endpoint (SUR): Blood pressure
Study 28642811 — Safety Biomarker (SAF): Interleukin 1
Study 23727316 — Predictive Biomarker (PRD): ANK3 mRNA
Genes: ANK3
Study 23740935 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23740935 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3277419 — Surrogate Endpoint (SUR): Blood pressure
Study 31018682 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19229704 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16846545 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16846545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16846545 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16846545 — Surrogate Endpoint (SUR): Serum uric acid
Study 12775859 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8403274 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6587752 — Surrogate Endpoint (SUR): Blood pressure
Study 18784543 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 12505969 — Surrogate Endpoint (SUR): Blood pressure
Study 12212217 — Surrogate Endpoint (SUR): Blood pressure
Study 8624760 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17667566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17667566 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16221223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11834952 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 583022 — Surrogate Endpoint (SUR): Blood pressure
Study 15265250 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11735866 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11367661 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 11367661 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26721229 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 17392122 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 17392122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15296685 — Surrogate Endpoint (SUR): Blood pressure
Study 10862530 — Surrogate Endpoint (SUR): Blood pressure
Study 10862530 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10862530 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10862530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25538086 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20493430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20493430 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20493430 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16854276 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16854276 — Monitoring Biomarker (MOI): HBV DNA
Study 8958889 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28639216 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 24568073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24568073 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24568073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24568073 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19551236 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15138687 — Surrogate Endpoint (SUR): Blood pressure
Study 7913949 — Surrogate Endpoint (SUR): Blood pressure
Study 7913949 — Surrogate Endpoint (SUR): Serum potassium
Study 2656133 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 26605505 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 16651205 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 12147926 — Surrogate Endpoint (SUR): Blood pressure
Study 9820705 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9820705 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9820705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9502783 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 1662578 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27930386 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 27341466 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 28339139 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 23232805 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 11225504 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 9433396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 22103994 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17723312 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 1942779 — Surrogate Endpoint (SUR): Serum creatinine
Study 1942779 — Surrogate Endpoint (SUR): Serum potassium
Study 26639039 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 25127483 — Surrogate Endpoint (SUR): Blood pressure
Study 19683936 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 2661155 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21590281 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 21590281 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 15298758 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15298758 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28590364 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 28590364 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 16880425 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1340835 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20151053 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20151053 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17702967 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11897771 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 11897771 — Surrogate Endpoint (SUR): Blood pressure
Study 10204835 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12172328 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 12172328 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 12172328 — Surrogate Endpoint (SUR): Blood pressure
Study 12685875 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 30183453 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9589379 — Surrogate Endpoint (SUR): Serum creatinine
Study 29191136 — Surrogate Endpoint (SUR): Blood pressure
Study 26714972 — Surrogate Endpoint (SUR): Serum potassium
Study 21287417 — Surrogate Endpoint (SUR): Blood pressure
Study 16645371 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10971787 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10971787 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 10971787 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 10971787 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10971787 — Surrogate Endpoint (SUR): Serum triglycerides
Study 1727841 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29257795 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29257795 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29257795 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24571483 — Surrogate Endpoint (SUR): Blood pressure
Study 17717914 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11057105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31842189 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31842189 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24434301 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24434301 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21890323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30033781 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 28105513 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study 28105513 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23903772 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19826309 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 19826309 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 19826309 — Predictive Biomarker (PRD): MYF5 mRNA
Genes: MYF5; BHLHC2
Study 12768357 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 12768357 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 10671905 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 29656744 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 25228778 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 25228778 — Surrogate Endpoint (SUR): Blood pressure
Study 25228778 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31440895 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 27173517 — Predictive Biomarker (PRD): miR-135b
Genes: MIR135B
Study 27173517 — Safety Biomarker (SAF): miR-183-5p
Genes: MIR183
Study 27173517 — Safety Biomarker (SAF): miR-183
Genes: MIR183
Study 27173517 — Safety Biomarker (SAF): miR-182-5p
Genes: MIR182
Study 27173517 — Safety Biomarker (SAF): miR-133a
Study 27173517 — Predictive Biomarker (PRD): miR-145
Genes: MIR145
Study 27173517 — Safety Biomarker (SAF): miR-30c
Study 24169612 — Surrogate Endpoint (SUR): Blood pressure
Study 21159499 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17077374 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 10827391 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22533659 — Surrogate Endpoint (SUR): Blood pressure
Study 19018483 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15671799 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15671799 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8681637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8681637 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 8681637 — Safety Biomarker (SAF): Interleukin 1
Study 27014997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24613784 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 8310980 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2647846 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2647846 — Surrogate Endpoint (SUR): Blood pressure
Study 28241386 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15039504 — Surrogate Endpoint (SUR): Blood pressure
Study 26499921 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26499921 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22900702 — Surrogate Endpoint (SUR): Blood pressure
Study 10640625 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 3799505 — Surrogate Endpoint (SUR): Blood pressure
Study 31514854 — Predictive Biomarker (PRD): NSMAF mRNA
Genes: NSMAF; FAN
Study 27884120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27884120 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 27146725 — Surrogate Endpoint (SUR): Blood pressure
Study 23639047 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19948873 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 11126178 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11126178 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 8648207 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1346562 — Surrogate Endpoint (SUR): Blood pressure
Study 20179259 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20179259 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17688921 — Predictive Biomarker (PRD): UBC mRNA
Genes: UBC
Study 6106828 — Surrogate Endpoint (SUR): Blood pressure
Study 28317828 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 21453706 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16330466 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15469418 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 15469418 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 29073803 — Surrogate Endpoint (SUR): Blood pressure
Study 19826112 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9859076 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 7631301 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31125767 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18471914 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15563708 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24457412 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 24457412 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 24457412 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 24457412 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22057424 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22057424 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22057424 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 21200103 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17374316 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 15838685 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 12181364 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 12181364 — Surrogate Endpoint (SUR): Blood pressure
Study 10460557 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31028057 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15798963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16678648 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 28436380 — Monitoring Biomarker (MOI): HBV DNA
Study 20133263 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20133263 — Predictive Biomarker (PRD): Hormone receptor
Study 8908676 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 23525950 — Predictive Biomarker (PRD): FCER1A mRNA
Genes: FCER1A; FCE1A
Study 23525950 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23525950 — Predictive Biomarker (PRD): ADAM33 mRNA
Genes: ADAM33; C20orf153; UNQ873/PRO1891
Study 23525950 — Predictive Biomarker (PRD): NANOS1 mRNA
Genes: NANOS1; NOS1
Study 23525950 — Predictive Biomarker (PRD): Interleukin 4 receptor alpha
Genes: IL4R; IL4RA; 582J2.1
Study 19687165 — Surrogate Endpoint (SUR): Blood pressure
Study 15523321 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8279987 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27912106 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 19828899 — Surrogate Endpoint (SUR): Blood pressure
Study 19828899 — Surrogate Endpoint (SUR): Serum calcium
Study 2533803 — Surrogate Endpoint (SUR): Blood pressure
Study 28631933 — Surrogate Endpoint (SUR): Blood pressure
Study 11061732 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28681996 — Predictive Biomarker (PRD): APLNR mRNA
Genes: APLNR; AGTRL1; APJ
Study 22913550 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16428086 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16428086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14659379 — Surrogate Endpoint (SUR): Blood pressure
Study 1688989 — Surrogate Endpoint (SUR): Blood pressure
Study 11798649 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1826883 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1826883 — Surrogate Endpoint (SUR): Blood pressure
Study 20576162 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 18775266 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11782036 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 11782036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30764699 — Surrogate Endpoint (SUR): Blood pressure
Study 26267985 — Surrogate Endpoint (SUR): Serum calcium
Study 17280678 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17280678 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3284271 — Surrogate Endpoint (SUR): Blood pressure
Study 12709737 — Surrogate Endpoint (SUR): Serum creatinine
Study 16298597 — Surrogate Endpoint (SUR): Serum creatinine
Study 16298597 — Surrogate Endpoint (SUR): Blood pressure
Study 18211118 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26295966 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 21090831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21090831 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10575333 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 6125625 — Surrogate Endpoint (SUR): Blood pressure
Study 28379623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28379623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24408122 — Surrogate Endpoint (SUR): Serum creatinine
Study 25666417 — Surrogate Endpoint (SUR): Blood pressure
Study 15466766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21511523 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 26233335 — Surrogate Endpoint (SUR): Blood pressure
Study 16763748 — Surrogate Endpoint (SUR): Bone mineral density
Study 29304065 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 23093337 — Surrogate Endpoint (SUR): Blood pressure
Study 23093337 — Surrogate Endpoint (SUR): Bone mineral density
Study 20019087 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18594001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17189542 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 6322985 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31396667 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 30611996 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 30611996 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 30611996 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 30611996 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 30611996 — Predictive Biomarker (PRD): MAPK1 mRNA
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study 22805422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22805422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11696462 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11696462 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 7870845 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 2975951 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 2975951 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28822719 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28822719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28822719 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 18840107 — Surrogate Endpoint (SUR): Blood pressure
Study 14638544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14638544 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20082754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20082754 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2467117 — Surrogate Endpoint (SUR): Blood pressure
Study 12576167 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 20540635 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2337713 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2337713 — Surrogate Endpoint (SUR): Blood pressure
Study 25056413 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 25056413 — Surrogate Endpoint (SUR): Probing pocket depth