TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04587687 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00004248 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01896999 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00005902 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT04420884 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04059484 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04059484 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02951130 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02951130 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02752685 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02752685 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02752685 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03368742 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03970226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01784068 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01784068 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03141021 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT04625270 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT04625270 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT00342927 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00342927 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02913430 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02913430 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT06072235 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03231306 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT03032107 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01466660 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01466660 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01318278 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00083512 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00083512 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02859766 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02859766 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02927704 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT01772472 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02522390 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04134117 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02391688 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT02391688 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT02391688 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02391688 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02391688 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00814827 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04704921 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04704921 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01411163 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03781414 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT00867269 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00867269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02000050 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01846676 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04526106 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT03382158 — Predictive Biomarker (PRD): DICER1 mRNA
Genes: DICER1; DICER; HERNA; KIAA0928
Study NCT05210686 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02841579 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01932320 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00903617 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00903617 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01352975 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03960580 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT04184414 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04184414 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT05331053 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study NCT05331053 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04146441 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT04324164 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01698905 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01698905 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02724488 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00885599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04082650 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT03893240 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT05901077 — Predictive Biomarker (PRD): CTNS mRNA
Genes: CTNS
Study NCT00001350 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02313727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03164317 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03761108 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03402009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01861106 — Predictive Biomarker (PRD): GATA2 mRNA
Genes: GATA2
Study NCT01145196 — Predictive Biomarker (PRD): ABCA4 mRNA
Genes: ABCA4; ABCR
Study NCT01371630 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT01200953 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00223171 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04690920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02388490 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT04144023 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02024100 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01897480 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04231331 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04231331 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00341497 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT00006150 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT00006150 — Predictive Biomarker (PRD): DOCK8 mRNA
Genes: DOCK8
Study NCT01273168 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03392987 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03392987 — Predictive Biomarker (PRD): ARSA mRNA
Genes: ARSA
Study NCT02692846 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03484364 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01432847 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02544022 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT04390425 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02879695 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01247597 — Predictive Biomarker (PRD): DICER1 mRNA
Genes: DICER1; DICER; HERNA; KIAA0928
Study NCT02972619 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02972619 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT01459653 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT04186650 — Predictive Biomarker (PRD): COL7A1 mRNA
Genes: COL7A1
Study NCT02115282 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02069015 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01131169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04079153 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06667648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03709199 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03650894 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03307863 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT03523572 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03523572 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03757650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT03803774 — Predictive Biomarker (PRD): BIRC2 mRNA
Genes: BIRC2; API1; MIHB; RNF48
Study NCT00001727 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study NCT04362085 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01730833 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01921374 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00174863 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT01212211 — Surrogate Endpoint (SUR): Serum sodium
Study NCT03351816 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT03198650 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03065062 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03065062 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03321045 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02747004 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02747004 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02747004 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02747004 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00071526 — Predictive Biomarker (PRD): SLC23A1 mRNA
Genes: SLC23A1; SVCT1; YSPL3
Study NCT00071526 — Predictive Biomarker (PRD): SLC23A2 mRNA
Genes: SLC23A2; KIAA0238; NBTL1; SLC23A1; SVCT2; YSPL2
Study NCT02203526 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01904916 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01904916 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03871257 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00719719 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00770042 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02789670 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT00686322 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT00101816 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00101816 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03826836 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02446236 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04427072 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT03213665 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study NCT03565913 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT03565913 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00798369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02460783 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study NCT04407182 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00006240 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01915212 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02194738 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02194738 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02194738 — Predictive Biomarker (PRD): SH3PXD2A mRNA
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study NCT03441971 — Predictive Biomarker (PRD): PLVAP mRNA
Genes: PLVAP; FELS; PV1
Study NCT03243214 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03243214 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT05927454 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05927454 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05927454 — Safety Biomarker (SAF): Interleukin 1
Study NCT00588822 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02276872 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01220479 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01220479 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02671435 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT06274541 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06274541 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03583333 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study NCT04466098 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04466098 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00709527 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT00709527 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04288128 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study NCT01780714 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01780714 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study NCT03793023 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02120092 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04000971 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03473964 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT03952598 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT03952598 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT03952598 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study NCT03636438 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT01161550 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02640625 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00775853 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00824551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00824551 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT00824551 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00824551 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02485652 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02485652 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02461615 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03460301 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study NCT02919631 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00485719 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03213678 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03213678 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study NCT05985811 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03229265 — Surrogate Endpoint (SUR): Serum potassium
Study NCT01758328 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT03833479 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03833479 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01143480 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT01143480 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study NCT02511002 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00006421 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00006421 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03842969 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01159171 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02477501 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03476083 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03191383 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03742258 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study NCT03095066 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT03638908 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03638908 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT03638908 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00801034 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00733109 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT04240002 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT03314727 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03314727 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study NCT03314727 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT02263430 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03426592 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04378829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03139851 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00073801 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT00632333 — Predictive Biomarker (PRD): TTK mRNA
Genes: TTK; MPS1; MPS1L1
Study NCT00632333 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00632333 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT04444596 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04752956 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02978547 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT04194944 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT04425057 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05983055 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00783445 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03657134 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03598244 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04223765 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT03874741 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00313144 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT01839591 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT01839591 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04185649 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02897037 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT03136497 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05596617 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04312399 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04312399 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study NCT04166409 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00639756 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03819556 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT04518852 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT04276870 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03076021 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01799538 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT06678152 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study NCT06678152 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03233646 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study NCT03306745 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF