TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02398435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02398435 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT01272700 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00878371 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study NCT00878371 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study NCT05284929 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study NCT05284929 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study NCT00169559 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02397161 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT04700644 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01981525 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT01981525 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01981525 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01981525 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study NCT02076061 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT01323101 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT04188561 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00243542 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT01667939 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT01667939 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04793425 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03398577 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02981680 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00692432 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT00692432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00692432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00692432 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT00692432 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00692432 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03956654 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03956654 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02342015 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT02342015 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT03823469 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01567540 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT01567540 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study NCT02991872 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00521404 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study NCT00681278 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03038880 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03038880 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study NCT03201874 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01131884 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04651946 — Predictive Biomarker (PRD): OPCML mRNA
Genes: OPCML; IGLON1; OBCAM
Study NCT04651946 — Predictive Biomarker (PRD): Cadherin-13
Genes: CDH13; CDHH
Study NCT04651946 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00063479 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01088698 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03298022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03478709 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02000869 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02000869 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02090322 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04163250 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT04163250 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study NCT03809104 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study NCT03461029 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00005706 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03682770 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT01431664 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02342548 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04223934 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03008057 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT03008057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03008057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04486170 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04513431 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00500526 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02849899 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02849899 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01967576 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01967576 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02772367 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02858362 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02369796 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT03916913 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02285725 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02945488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01902550 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04514653 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04514653 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04504331 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03083834 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study NCT00201240 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05595044 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study NCT00476879 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01986543 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT02428257 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01394146 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03625310 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT04994119 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00005879 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03633773 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT02803190 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02764073 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04091997 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT00585507 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03944538 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00752401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00752401 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01575067 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03440294 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02856113 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01468298 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01468298 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00378365 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study NCT03631836 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT03286517 — Predictive Biomarker (PRD): KISS1R mRNA
Genes: KISS1R; AXOR12; GPR54
Study NCT01481818 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00264732 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT04087473 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01920204 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT00127907 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT02587533 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03329235 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00089908 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01926561 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00339976 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT01072643 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT01072643 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03667066 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT00129181 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT00706134 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05535049 — Safety Biomarker (SAF): Interleukin 1
Study NCT05535049 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05535049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02454842 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01918306 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01770158 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYH11 mRNA
Genes: MYH11; KIAA0866
Study NCT01770158 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00943670 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03798067 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03970239 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT06065566 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT06065566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06065566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT04000152 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00858039 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00858039 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01219387 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00387868 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01668589 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00244023 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT00244023 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT01870401 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03982446 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03982446 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04364113 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03409003 — Predictive Biomarker (PRD): Mitochondrial n-acetylglutamate synthase
Genes: NAGS
Study NCT01703780 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00000426 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02074696 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02074696 — Safety Biomarker (SAF): BDNF
Study NCT00435825 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00350194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00350194 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00006385 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02996448 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT00062036 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02015299 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04608344 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study NCT04608344 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT01707472 — Predictive Biomarker (PRD): LOXL2 mRNA
Genes: LOXL2
Study NCT03591367 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT01238562 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00185081 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01431872 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study NCT00670748 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT01287741 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00911209 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04473456 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01678183 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04581213 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00880243 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02824653 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03685786 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03714958 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT03714958 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT03714958 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT03714958 — Predictive Biomarker (PRD): MDM2
Genes: HDM2; MGC5370
Study NCT03223064 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01209689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03740256 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04179669 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01968135 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT03478098 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02213809 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT03926897 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01443351 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT05510232 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03995602 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01161368 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03261752 — Predictive Biomarker (PRD): STK31 mRNA
Genes: STK31; SGK396
Study NCT02595489 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT03246737 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04049045 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04049045 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04490876 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT01734018 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03200288 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00079963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04646044 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT06413251 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00764816 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01528046 — Predictive Biomarker (PRD): VIT mRNA
Genes: VIT; UNQ647/PRO1277
Study NCT00171756 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02987790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02987790 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02376699 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04209816 — Predictive Biomarker (PRD): TM6SF2 mRNA
Genes: TM6SF2
Study NCT04209816 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04209816 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study NCT04209816 — Predictive Biomarker (PRD): ANGPTL8 mRNA
Genes: ANGPTL8; C19orf80; RIFL; UNQ599/PRO1185
Study NCT04209816 — Predictive Biomarker (PRD): LIPG mRNA
Genes: LIPG; UNQ387/PRO719
Study NCT01789372 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03350217 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02918019 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT02481388 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT01891331 — Predictive Biomarker (PRD): CYP51A1 mRNA
Genes: CYP51A1; CYP51
Study NCT01337674 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00664898 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT02660723 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT01128803 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT01318057 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01318057 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT03534427 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03534427 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT03534427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00055913 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06359353 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04821479 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03963154 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT02673398 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03003728 — Predictive Biomarker (PRD): SLAMF7 mRNA
Genes: SLAMF7; CS1; UNQ576/PRO1138
Study NCT04320316 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT03038906 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT03672838 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT03672838 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT04560699 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04318184 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04550325 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02640417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04811911 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study NCT03743870 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04609176 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT02778490 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01498705 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03218319 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01036048 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT04587661 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03005158 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT00867672 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT03846206 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00335582 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04366063 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00582257 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT01233128 — Predictive Biomarker (PRD): HTRA1 mRNA
Genes: HTRA1; HTRA; PRSS11
Study NCT01233128 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01388335 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT05113836 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study NCT01288261 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01288261 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03524261 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT00163683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00163683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04168606 — Predictive Biomarker (PRD): PAPPA mRNA
Genes: PAPPA
Study NCT02870309 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT04379622 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04379622 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00141739 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study NCT00141739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2