TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00043342 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00275561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04023747 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT02093702 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02617238 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03179904 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study NCT03179904 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03262363 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study NCT02123251 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT01343641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01343641 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT04622488 — Surrogate Endpoint (SUR): Bacterial count
Study NCT03624257 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT03406091 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT03406091 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT01030081 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03264703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01075360 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study NCT01075360 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study NCT01075360 — Predictive Biomarker (PRD): E2F1 mRNA
Genes: E2F1; RBBP3
Study NCT00757263 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00757263 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03592979 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00448318 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01533740 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01533740 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT00005264 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00286117 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01379079 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00674596 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study NCT00674596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00674596 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00977756 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT02722057 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04170972 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study NCT00276289 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02502656 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01325259 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01325259 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01715974 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00564057 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00406107 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01977963 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study NCT01977963 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT04466878 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03436758 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01057875 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03873740 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02899442 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05589428 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02012959 — Surrogate Endpoint (SUR): Serum sodium
Study NCT03690310 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT06536452 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT00263328 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study NCT00808743 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT01258439 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT02249897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01987908 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02366091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00217919 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00341614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00341614 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00341614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00341614 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03404999 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01105065 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01410344 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02122913 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT02122913 — Predictive Biomarker (PRD): NTRK2 mRNA
Genes: NTRK2; TRKB
Study NCT02122913 — Predictive Biomarker (PRD): NTRK3 mRNA
Genes: NTRK3; TRKC
Study NCT00794898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03539731 — Predictive Biomarker (PRD): PKM mRNA
Genes: PKM; OIP3; PK2; PK3; PKM2
Study NCT03576430 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04641754 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04641754 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT00904839 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03472508 — Safety Biomarker (SAF): MTHFR
Study NCT03472508 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01632267 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01632267 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01632267 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01632267 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study NCT03294304 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT02952937 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01188070 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03160794 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT05085509 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT02607605 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04619069 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01262183 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01262183 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01989468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01989468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02521831 — Predictive Biomarker (PRD): SLC22A4 mRNA
Genes: SLC22A4; ETT; OCTN1; UT2H
Study NCT03773302 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT03773302 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT01896284 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01896284 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04064437 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01241383 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04146246 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT03507621 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT00815555 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01546623 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT01546623 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study NCT02087436 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02153502 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT04541914 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT02893111 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT00294099 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00888238 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00003137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00003137 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT02682680 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01701050 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01701050 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00844727 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT00616707 — Safety Biomarker (SAF): Urinary microalbumin
Study NCT05176132 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01676506 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03112733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study NCT03112733 — Predictive Biomarker (PRD): SFRP4 mRNA
Genes: SFRP4; FRPHE
Study NCT00688922 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01155128 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03311958 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03911427 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT02383121 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04034667 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04034667 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04034667 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT04034667 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02691585 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02576145 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT04268628 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HSD3B1 mRNA
Genes: HSD3B1; 3BH; HSDB3A
Study NCT03502850 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03502850 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00896532 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01176916 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00051636 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT02500186 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00470509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03263871 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study NCT01425099 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00578643 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04912635 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00464880 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02065388 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02065388 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT03772288 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT02949830 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study NCT02440581 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02440581 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01811511 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02886299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00004086 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03764566 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04287309 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02550288 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02807415 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03287271 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT03538171 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03538171 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03538171 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04405674 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04405674 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00000485 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00679445 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00679445 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04136015 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04136015 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04215965 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03701035 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03701035 — Safety Biomarker (SAF): BDNF
Study NCT02604901 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04330729 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study NCT01468311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT05757258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05757258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02382133 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03636906 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04498481 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04498481 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04498481 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04498481 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04561726 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01934647 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01934647 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT01934647 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01903681 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study NCT00974584 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study NCT01753206 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01385397 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03837626 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04598035 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04641442 — Predictive Biomarker (PRD): NLRC4 mRNA
Genes: NLRC4; CARD12; CLAN; CLAN1; IPAF; UNQ6189/PRO20215
Study NCT04641442 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study NCT02689921 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02689921 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02689921 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02689921 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02069964 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04055428 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study NCT04055428 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03559803 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03559803 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study NCT03559803 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03559803 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04619160 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02490020 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00095940 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03252574 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00524394 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study NCT00783484 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00970385 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT00988650 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00988650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00988650 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02294578 — Safety Biomarker (SAF): Cellular communication network factor 1
Genes: CCN1; CYR61; GIG1; IGFBP10
Study NCT02294578 — Predictive Biomarker (PRD): FRS2 mRNA
Genes: FRS2
Study NCT02294578 — Predictive Biomarker (PRD): GREB1 mRNA
Genes: GREB1; KIAA0575
Study NCT02294578 — Predictive Biomarker (PRD): LZTS1 mRNA
Genes: LZTS1; FEZ1
Study NCT02058732 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02278692 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT03178019 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03178019 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01926925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01926925 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01926925 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01926925 — Safety Biomarker (SAF): Urinary microalbumin
Study NCT04051957 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04051957 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01977885 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01977885 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00522925 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01307033 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00154089 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03475979 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03743831 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00445302 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04483401 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT02855918 — Predictive Biomarker (PRD): PDE8A mRNA
Genes: PDE8A
Study NCT02855918 — Predictive Biomarker (PRD): ADARB1 mRNA
Genes: ADARB1; ADAR2; DRADA2; RED1
Study NCT01450852 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study NCT01450852 — Predictive Biomarker (PRD): MC3R mRNA
Genes: MC3R
Study NCT01450852 — Predictive Biomarker (PRD): MC5R mRNA
Genes: MC5R
Study NCT02716012 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study NCT04334330 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03975088 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02407093 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02503566 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study NCT01445535 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study NCT02316678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02020785 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01547559 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT00423059 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00423059 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study NCT02661763 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT01990157 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study NCT00782275 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00782275 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study NCT00782275 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03386669 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01705704 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT04586335 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04586335 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT03084380 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT00852514 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01633957 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01633957 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351