TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16289360 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 16289360 — Safety Biomarker (SAF): BDNF
Study 9024262 — Predictive Biomarker (PRD): GCSAM mRNA
Genes: GCSAM; GAL; GCET2
Study 9024262 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9024262 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9024262 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3142400 — Surrogate Endpoint (SUR): Blood pressure
Study 17058824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17058824 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12027846 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10323377 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6271814 — Surrogate Endpoint (SUR): Blood pressure
Study 25646201 — Surrogate Endpoint (SUR): Blood pressure
Study 15176536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28274253 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28274253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25567115 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 20489031 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 20489031 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20489031 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18064444 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 16126119 — Surrogate Endpoint (SUR): Blood pressure
Study 23421088 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 7662761 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29029237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29029237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23873255 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 17302372 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 6619040 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 12030546 — Surrogate Endpoint (SUR): Bone mineral density
Study 1847582 — Surrogate Endpoint (SUR): Bone mineral density
Study 1847582 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25870994 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23175179 — Surrogate Endpoint (SUR): Blood pressure
Study 2121079 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24807396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24807396 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 3074627 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 3074627 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10497712 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19500328 — Predictive Biomarker (PRD): NMI mRNA
Genes: NMI
Study 26874390 — Surrogate Endpoint (SUR): Blood pressure
Study 11344825 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11344825 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8217793 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 15226691 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24035250 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 24035250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21118028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16565959 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 16565959 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 10910439 — Surrogate Endpoint (SUR): Blood pressure
Study 1558156 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1558156 — Surrogate Endpoint (SUR): Blood pressure
Study 31304554 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31304554 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23864249 — Surrogate Endpoint (SUR): Bone mineral density
Study 11317685 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7957539 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30703663 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 25791747 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29039261 — Surrogate Endpoint (SUR): Blood pressure
Study 27343147 — Surrogate Endpoint (SUR): Blood pressure
Study 22722502 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 8624969 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16818127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16818127 — Safety Biomarker (SAF): Interleukin 1
Study 18266651 — Surrogate Endpoint (SUR): Serum testosterone
Study 15197517 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 3305355 — Surrogate Endpoint (SUR): Blood pressure
Study 15818323 — Surrogate Endpoint (SUR): Serum creatinine
Study 25191937 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 17645805 — Surrogate Endpoint (SUR): Blood pressure
Study 30345312 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 30345312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27623769 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9857272 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3337027 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27687394 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 22858430 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22858430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22858430 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 8739822 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29221978 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 29221978 — Surrogate Endpoint (SUR): Serum creatinine
Study 29221978 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9189307 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28393570 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 18258511 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 18258511 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 2870810 — Surrogate Endpoint (SUR): Blood pressure
Study 26111953 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22634184 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 22634184 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12361993 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 26358331 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 17218551 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29731413 — Surrogate Endpoint (SUR): Serum testosterone
Study 18058457 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18058457 — Surrogate Endpoint (SUR): Blood pressure
Study 31912799 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 31912799 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 24092829 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24092829 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24092829 — Surrogate Endpoint (SUR): Serum calcium
Study 2527829 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 28051986 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 21111078 — Surrogate Endpoint (SUR): Bone mineral density
Study 30826617 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 30826617 — Predictive Biomarker (PRD): NELFE mRNA
Genes: NELFE; RD; RDBP
Study 30826617 — Predictive Biomarker (PRD): SIGLEC1 mRNA
Genes: SIGLEC1; SN
Study 21980964 — Surrogate Endpoint (SUR): Blood pressure
Study 21980964 — Surrogate Endpoint (SUR): Serum creatinine
Study 17063170 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17063170 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29309832 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25903215 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25903215 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30284097 — Surrogate Endpoint (SUR): Blood pressure
Study 16084879 — Surrogate Endpoint (SUR): Bone mineral density
Study 16084879 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16084879 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16084879 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16084879 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 23430981 — Predictive Biomarker (PRD): MTRR mRNA
Genes: MTRR
Study 23430981 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 23430981 — Safety Biomarker (SAF): MTHFR
Study 9893074 — Surrogate Endpoint (SUR): Bone mineral density
Study 30848805 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16249194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16249194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28619236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28619236 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27035272 — Safety Biomarker (SAF): MTHFR
Study 19117641 — Predictive Biomarker (PRD): PHF1 mRNA
Genes: PHF1; PCL1
Study 19117641 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study 19117641 — Predictive Biomarker (PRD): MBD2 mRNA
Genes: MBD2
Study 19117641 — Predictive Biomarker (PRD): RPL26 mRNA
Genes: RPL26
Study 12186348 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 12186348 — Surrogate Endpoint (SUR): Probing pocket depth
Study 1750018 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16996600 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 549782 — Surrogate Endpoint (SUR): Serum uric acid
Study 549782 — Surrogate Endpoint (SUR): Serum potassium
Study 31581605 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 30820940 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 3400843 — Surrogate Endpoint (SUR): Blood pressure
Study 28373411 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 18507269 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18507269 — Surrogate Endpoint (SUR): Blood pressure
Study 14561977 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 1451715 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29133220 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 29133220 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25668306 — Surrogate Endpoint (SUR): Bone mineral density
Study 18368947 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11100349 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 8383933 — Surrogate Endpoint (SUR): Blood pressure
Study 8383933 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31615775 — Surrogate Endpoint (SUR): Serum testosterone
Study 28984843 — Surrogate Endpoint (SUR): Blood pressure
Study 19419923 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19419923 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15976996 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 8447444 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8447444 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21562038 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 12603782 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 9266782 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20883237 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 20883237 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30443729 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 12589011 — Surrogate Endpoint (SUR): Blood pressure
Study 6672890 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 17130263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17130263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8037993 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30297735 — Surrogate Endpoint (SUR): Blood pressure
Study 17086017 — Surrogate Endpoint (SUR): Blood pressure
Study 17086017 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17086017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31577876 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21940716 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 21940716 — Surrogate Endpoint (SUR): Serum calcium
Study 18198986 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17504997 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ADAM11 mRNA
Genes: ADAM11; MDC
Study 17504997 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 17504997 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 17504997 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17504997 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 15188947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18638594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18638594 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18638594 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24519767 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 24519767 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 20514964 — Surrogate Endpoint (SUR): Blood pressure
Study 16623401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2893187 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21541241 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19541016 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10101928 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10101928 — Surrogate Endpoint (SUR): Blood pressure
Study 678373 — Surrogate Endpoint (SUR): Serum potassium
Study 29761313 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 29761313 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 29761313 — Predictive Biomarker (PRD): PLCG2 mRNA
Genes: PLCG2
Study 29761313 — Predictive Biomarker (PRD): MAPK10 mRNA
Genes: MAPK10; JNK3; JNK3A; PRKM10; SAPK1B
Study 21610441 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 21610441 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 27578124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27578124 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 15892078 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15892078 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 15892078 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15892078 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8803306 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8803306 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29606104 — Safety Biomarker (SAF): Reactive oxygen species
Study 27252841 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10817552 — Safety Biomarker (SAF): Interleukin 1
Study 6228370 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 16989497 — Surrogate Endpoint (SUR): Blood pressure
Study 29771607 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27598024 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 7611760 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 356254 — Surrogate Endpoint (SUR): Blood pressure
Study 16364832 — Surrogate Endpoint (SUR): Blood pressure
Study 24206099 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 15168891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27825893 — Surrogate Endpoint (SUR): Blood pressure
Study 16706261 — Surrogate Endpoint (SUR): Blood pressure
Study 16706261 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31948301 — Surrogate Endpoint (SUR): Blood pressure
Study 27053407 — Surrogate Endpoint (SUR): Blood pressure
Study 27053407 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17261975 — Surrogate Endpoint (SUR): Bone mineral density
Study 29902542 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24838790 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24838790 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 22750962 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 17082176 — Predictive Biomarker (PRD): EPHX1 mRNA
Genes: EPHX1; EPHX; EPOX
Study 17082176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 15746294 — Surrogate Endpoint (SUR): Bone mineral density
Study 30624012 — Surrogate Endpoint (SUR): Blood pressure
Study 28246236 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28246236 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24573974 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 23347535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23347535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21872376 — Surrogate Endpoint (SUR): Serum creatinine
Study 21872376 — Surrogate Endpoint (SUR): Blood pressure
Study 21872376 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19805398 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9527193 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24609887 — Safety Biomarker (SAF): Interleukin 1
Study 20164847 — Surrogate Endpoint (SUR): Blood pressure
Study 11896093 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27686059 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27686059 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 19817197 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10220004 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 7596934 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7596934 — Surrogate Endpoint (SUR): Blood pressure
Study 15685505 — Surrogate Endpoint (SUR): Blood pressure
Study 28357975 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 26610598 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16978615 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 15365313 — Surrogate Endpoint (SUR): Blood pressure
Study 10931079 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10931079 — Surrogate Endpoint (SUR): Serum testosterone
Study 7876402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 31770016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23819242 — Surrogate Endpoint (SUR): Blood pressure
Study 21059094 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16996844 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30803885 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 26045114 — Predictive Biomarker (PRD): NDC80 mRNA
Genes: NDC80; HEC; HEC1; KNTC2
Study 23458673 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 9098292 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 2180481 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2180481 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31775412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31775412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31775412 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF