TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30549271 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30549271 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 30549271 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30549271 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30549271 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23843375 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9893589 — Predictive Biomarker (PRD): KCNMA1 mRNA
Genes: KCNMA1; KCNMA; SLO
Study 8594942 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8594942 — Surrogate Endpoint (SUR): Blood pressure
Study 10634176 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27980008 — Surrogate Endpoint (SUR): Serum uric acid
Study 4085468 — Predictive Biomarker (PRD): IRS2 mRNA
Genes: IRS2
Study 29997249 — Predictive Biomarker (PRD): CRTC1 mRNA
Genes: CRTC1; KIAA0616; MECT1; TORC1; WAMTP1
Study 30450637 — Predictive Biomarker (PRD): SLC52A2 mRNA
Genes: SLC52A2; GPR172A; PAR1; RFT3
Study 19116919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11212971 — Surrogate Endpoint (SUR): Blood pressure
Study 25011982 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 25011982 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 25011982 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 25011982 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 11313303 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9141002 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3343933 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 28633089 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26297704 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26297704 — Surrogate Endpoint (SUR): Blood pressure
Study 12883662 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 12372124 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12372124 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10449884 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28797783 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28797783 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26694073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8776210 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1730080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6085363 — Surrogate Endpoint (SUR): Blood pressure
Study 25238062 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 14694177 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 14694177 — Surrogate Endpoint (SUR): Serum creatinine
Study 30739519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25407559 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 24267123 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19711612 — Surrogate Endpoint (SUR): Probing pocket depth
Study 30646209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30646209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28449631 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28449631 — Surrogate Endpoint (SUR): Blood pressure
Study 21084567 — Surrogate Endpoint (SUR): Blood pressure
Study 15325680 — Surrogate Endpoint (SUR): Bone mineral density
Study 9564804 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25716880 — Predictive Biomarker (PRD): SPART mRNA
Genes: SPART; KIAA0610; SPG20; TAHCCP1
Study 19967581 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16645152 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 16645152 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30116124 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22202972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16296572 — Surrogate Endpoint (SUR): Blood pressure
Study 2223342 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 30935866 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 22226275 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 19687024 — Predictive Biomarker (PRD): ALKBH1 mRNA
Genes: ALKBH1; ABH; ABH1; ALKBH
Study 17596064 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23925396 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 23925396 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 19309415 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 13129740 — Surrogate Endpoint (SUR): Serum creatinine
Study 12186343 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10568044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8923571 — Surrogate Endpoint (SUR): Blood pressure
Study 2009366 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 7171417 — Surrogate Endpoint (SUR): Serum potassium
Study 31348298 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 30477832 — Surrogate Endpoint (SUR): Blood pressure
Study 20226040 — Predictive Biomarker (PRD): AKAP11 mRNA
Genes: AKAP11; AKAP220; KIAA0629
Study 20226040 — Predictive Biomarker (PRD): BMPR2 mRNA
Genes: BMPR2; PPH1
Study 20226040 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25012183 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 20877394 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20877394 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1637767 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20443719 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20443719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17355218 — Predictive Biomarker (PRD): MTLN mRNA
Genes: MTLN; LEMP; LINC00116; MOXI; MPM; NCRNA00116; SMIM37
Study 16287371 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 2260727 — Surrogate Endpoint (SUR): Blood pressure
Study 15897799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12201833 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 12201833 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 2540786 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21745357 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 8095854 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3094207 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22183484 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 411668 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 411668 — Surrogate Endpoint (SUR): Blood pressure
Study 1713930 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31358336 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30530975 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27339779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12033702 — Surrogate Endpoint (SUR): Blood pressure
Study 1976051 — Surrogate Endpoint (SUR): Blood pressure
Study 29150250 — Surrogate Endpoint (SUR): Blood pressure
Study 19084088 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 9342579 — Surrogate Endpoint (SUR): Blood pressure
Study 2878607 — Surrogate Endpoint (SUR): Serum creatinine
Study 17925589 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11702012 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8988921 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8988921 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24716215 — Monitoring Biomarker (MOI): HBV DNA
Study 20864862 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 1292337 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 1292337 — Safety Biomarker (SAF): Interleukin 1
Study 29954931 — Surrogate Endpoint (SUR): Serum creatinine
Study 25847557 — Surrogate Endpoint (SUR): Blood pressure
Study 22615029 — Predictive Biomarker (PRD): PPP1R13L mRNA
Genes: PPP1R13L; IASPP; NKIP1; PPP1R13BL; RAI
Study 9377132 — Surrogate Endpoint (SUR): Serum sodium
Study 3297468 — Surrogate Endpoint (SUR): Blood pressure
Study 31912695 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 31912695 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16258165 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 16258165 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21215143 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20415152 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17938383 — Surrogate Endpoint (SUR): Blood pressure
Study 17938383 — Safety Biomarker (SAF): Urinary microalbumin
Study 15739120 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 3049876 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27612501 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16861942 — Surrogate Endpoint (SUR): Serum creatinine
Study 22474419 — Predictive Biomarker (PRD): PDGFRB
Genes: JTK12; CD140b; PDGFR1
Study 17634484 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 30664816 — Surrogate Endpoint (SUR): Blood pressure
Study 25421981 — Surrogate Endpoint (SUR): Blood pressure
Study 25421981 — Surrogate Endpoint (SUR): Serum creatinine
Study 23171375 — Surrogate Endpoint (SUR): Blood pressure
Study 7952357 — Safety Biomarker (SAF): Hyaluronic acid
Study 27254034 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17891480 — Surrogate Endpoint (SUR): Blood pressure
Study 16025736 — Surrogate Endpoint (SUR): Blood pressure
Study 16025736 — Safety Biomarker (SAF): Reactive oxygen species
Study 10423597 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10423597 — Surrogate Endpoint (SUR): Serum creatinine
Study 3665737 — Surrogate Endpoint (SUR): Blood pressure
Study 30043749 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 30043749 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 20339969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20339969 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30706792 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30706792 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26014294 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22013796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17284923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11900820 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 11900820 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 28052977 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21546102 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 21546102 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 26565690 — Surrogate Endpoint (SUR): Blood pressure
Study 17570262 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 8665540 — Surrogate Endpoint (SUR): Blood pressure
Study 27236884 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27236884 — Surrogate Endpoint (SUR): Blood pressure
Study 24872682 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 11978287 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29357894 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23037612 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21235330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19207276 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 7975357 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7975357 — Surrogate Endpoint (SUR): Blood pressure
Study 17848650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9355669 — Surrogate Endpoint (SUR): Bone mineral density
Study 23963046 — Surrogate Endpoint (SUR): Blood pressure
Study 15785088 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 10716202 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 2220013 — Surrogate Endpoint (SUR): Blood pressure
Study 25938681 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 31425456 — Surrogate Endpoint (SUR): Blood pressure
Study 30040140 — Surrogate Endpoint (SUR): Bone mineral density
Study 25322607 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17593932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16720676 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 16720676 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 10470219 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21084767 — Predictive Biomarker (PRD): SLC15A2 mRNA
Genes: SLC15A2; PEPT2
Study 22697581 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17178264 — Surrogate Endpoint (SUR): Blood pressure
Study 17178264 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 17178264 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12812863 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 29506460 — Monitoring Biomarker (MOI): Procalcitonin
Study 18981503 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 1145988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31385202 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31385202 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27217412 — Surrogate Endpoint (SUR): Blood pressure
Study 20040338 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 20040338 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 20040338 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 17976224 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3147477 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 21157106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21157106 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19118120 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15166558 — Surrogate Endpoint (SUR): Blood pressure
Study 28450350 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28450350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3912621 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30954261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30954261 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 30954261 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 30954261 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24300266 — Surrogate Endpoint (SUR): Blood pressure
Study 15734615 — Surrogate Endpoint (SUR): Blood pressure
Study 12899316 — Surrogate Endpoint (SUR): Blood pressure
Study 1723378 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28526225 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 17317931 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11193249 — Surrogate Endpoint (SUR): Bone mineral density
Study 3887847 — Surrogate Endpoint (SUR): Blood pressure
Study 20071701 — Safety Biomarker (SAF): Interleukin 12
Study 20071701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7594088 — Surrogate Endpoint (SUR): Blood pressure
Study 1988576 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 23856660 — Safety Biomarker (SAF): MTHFR
Study 23856660 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17513706 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 17513706 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 17513706 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 11427221 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11427221 — Surrogate Endpoint (SUR): Blood pressure
Study 11427221 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11427221 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9732339 — Surrogate Endpoint (SUR): Blood pressure
Study 9732339 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22773551 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26968644 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study 20087332 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12562875 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 12562875 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 3933320 — Surrogate Endpoint (SUR): Blood pressure
Study 28495863 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 28495863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14769716 — Surrogate Endpoint (SUR): Serum potassium
Study 8988937 — Surrogate Endpoint (SUR): Blood pressure
Study 8406350 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8406350 — Monitoring Biomarker (MOI): HBV DNA
Study 8406350 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2446054 — Surrogate Endpoint (SUR): Blood pressure
Study 31429794 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19191657 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9229195 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9229195 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8250301 — Surrogate Endpoint (SUR): Blood pressure
Study 4041341 — Surrogate Endpoint (SUR): Blood pressure
Study 27389975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27389975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18618000 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 31551314 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31551314 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31551314 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 27518833 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 25497513 — Surrogate Endpoint (SUR): Blood pressure
Study 18052991 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 8816142 — Monitoring Biomarker (MOI): HBV DNA
Study 22502839 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17361105 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 7572695 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30308560 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 28386035 — Surrogate Endpoint (SUR): Blood pressure
Study 17606839 — Surrogate Endpoint (SUR): Blood pressure
Study 15249932 — Predictive Biomarker (PRD): DNAAF4 mRNA
Genes: DNAAF4; DYX1C1; EKN1
Study 8052271 — Safety Biomarker (SAF): Interleukin 1
Study 8052271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31142359 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 17536130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7702053 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26018925 — Surrogate Endpoint (SUR): Blood pressure
Study 21392641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21392641 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10096452 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 10096452 — Safety Biomarker (SAF): Interleukin 1
Study 7755942 — Surrogate Endpoint (SUR): Blood pressure
Study 28126304 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 7530984 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7530984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2221611 — Surrogate Endpoint (SUR): Serum creatinine
Study 26013912 — Surrogate Endpoint (SUR): Blood pressure
Study 24092242 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 24092242 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS