TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26792933 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26792933 — Surrogate Endpoint (SUR): Serum testosterone
Study 22897752 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9734938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9734938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29956440 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10931101 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8147961 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 30340503 — Surrogate Endpoint (SUR): Bone mineral density
Study 24758077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24758077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20547163 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 17340594 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15827107 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12474916 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 31073952 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 16202254 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11783214 — Predictive Biomarker (PRD): DDN mRNA
Genes: DDN; KIAA0749
Study 6165217 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30747394 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11477811 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17130503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20876826 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 12809173 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21127429 — Surrogate Endpoint (SUR): Blood pressure
Study 17097958 — Safety Biomarker (SAF): Reactive oxygen species
Study 7895951 — Surrogate Endpoint (SUR): Serum sodium
Study 7895951 — Surrogate Endpoint (SUR): Serum potassium
Study 31348308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31348308 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 28603901 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 24280479 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24280479 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24280479 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 24280479 — Surrogate Endpoint (SUR): Blood pressure
Study 21861719 — Surrogate Endpoint (SUR): Blood pressure
Study 3557731 — Surrogate Endpoint (SUR): Blood pressure
Study 25539929 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9543597 — Surrogate Endpoint (SUR): Blood pressure
Study 28671553 — Monitoring Biomarker (MOI): HBV DNA
Study 26987021 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 26987021 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 22252354 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 30451538 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30451538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30451538 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17318070 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17318070 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 23785020 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 14666956 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29985459 — Surrogate Endpoint (SUR): Blood pressure
Study 25281504 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17654295 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 17654295 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 17654295 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 17654295 — Safety Biomarker (SAF): DRD2
Study 31394910 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 27017151 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 27017151 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11182173 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11182173 — Surrogate Endpoint (SUR): Serum creatinine
Study 19686407 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 3532752 — Surrogate Endpoint (SUR): Blood pressure
Study 27084959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18552239 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10492111 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8559201 — Surrogate Endpoint (SUR): Serum calcium
Study 19245362 — Predictive Biomarker (PRD): IDE mRNA
Genes: IDE
Study 7655447 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 31597151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21883496 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19488681 — Surrogate Endpoint (SUR): Bone mineral density
Study 17335689 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12781094 — Surrogate Endpoint (SUR): Blood pressure
Study 9100167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3781678 — Surrogate Endpoint (SUR): Blood pressure
Study 27749603 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27749603 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 23414551 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 20096545 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8181259 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8181259 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20974293 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 20032546 — Monitoring Biomarker (MOI): HBV DNA
Study 14973216 — Surrogate Endpoint (SUR): Bone mineral density
Study 9677439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9677439 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 9677439 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2735177 — Predictive Biomarker (PRD): ANTXR1 mRNA
Genes: ANTXR1; ATR; TEM8
Study 2735177 — Predictive Biomarker (PRD): SDC1 mRNA
Genes: SDC1; SDC
Study 28244559 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28244559 — Safety Biomarker (SAF): BDNF
Study 15239097 — Monitoring Biomarker (MOI): HBV DNA
Study 15596679 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27297443 — Surrogate Endpoint (SUR): Bone mineral density
Study 23707930 — Surrogate Endpoint (SUR): Blood pressure
Study 18332401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18332401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18332401 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16520350 — Surrogate Endpoint (SUR): Blood pressure
Study 23249766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23249766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27368881 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27368881 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27368881 — Predictive Biomarker (PRD): Hormone receptor
Study 7669311 — Surrogate Endpoint (SUR): Blood pressure
Study 2279253 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 876918 — Surrogate Endpoint (SUR): Blood pressure
Study 19638505 — Predictive Biomarker (PRD): MAP2K4 mRNA
Genes: MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1
Study 11095445 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 3533025 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26823602 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26823602 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 26823602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26823602 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26823602 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 26823602 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 22496207 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 22496207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19085342 — Surrogate Endpoint (SUR): Blood pressure
Study 1656517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1656517 — Safety Biomarker (SAF): Interleukin 1
Study 25311333 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25311333 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 15969777 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6961762 — Surrogate Endpoint (SUR): Blood pressure
Study 12324991 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2560283 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2560283 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 26436470 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23599357 — Surrogate Endpoint (SUR): Serum uric acid
Study 12196361 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2649124 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21947813 — Surrogate Endpoint (SUR): Blood pressure
Study 20696980 — Surrogate Endpoint (SUR): Blood pressure
Study 11590519 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9453529 — Surrogate Endpoint (SUR): Blood pressure
Study 29366744 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29366744 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29366744 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 24685829 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7692110 — Surrogate Endpoint (SUR): Serum testosterone
Study 26679552 — Safety Biomarker (SAF): Hyaluronic acid
Study 22119930 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15078741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 27575546 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15063399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31599479 — Predictive Biomarker (PRD): GAS6 mRNA
Genes: GAS6; AXLLG
Study 31599479 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 30672256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26887115 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21922934 — Surrogate Endpoint (SUR): Blood pressure
Study 16749407 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16749407 — Surrogate Endpoint (SUR): Blood pressure
Study 22682553 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 7781752 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7781752 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7781752 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2194264 — Predictive Biomarker (PRD): SLC22A4 mRNA
Genes: SLC22A4; ETT; OCTN1; UT2H
Study 619948 — Surrogate Endpoint (SUR): Blood pressure
Study 6360431 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 6360431 — Surrogate Endpoint (SUR): Blood pressure
Study 30323581 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17506781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17506781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15945343 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 15945343 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2082945 — Surrogate Endpoint (SUR): Blood pressure
Study 17953336 — Surrogate Endpoint (SUR): Blood pressure
Study 16034041 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 10077414 — Surrogate Endpoint (SUR): Blood pressure
Study 30262813 — Surrogate Endpoint (SUR): Blood pressure
Study 7944415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7818111 — Surrogate Endpoint (SUR): Blood pressure
Study 20104156 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 17328057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17328057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17328057 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17328057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17328057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15316583 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2653386 — Predictive Biomarker (PRD): CRYM mRNA
Genes: CRYM; THBP
Study 17356003 — Surrogate Endpoint (SUR): Bone mineral density
Study 9798343 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 30745014 — Surrogate Endpoint (SUR): Blood pressure
Study 31290727 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 18081859 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 29318418 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 18698280 — Surrogate Endpoint (SUR): Bone mineral density
Study 30680547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28697211 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 21111685 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 11375342 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9163658 — Predictive Biomarker (PRD): SPX mRNA
Genes: SPX; C12orf39
Study 23011683 — Surrogate Endpoint (SUR): Bone mineral density
Study 16809727 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19932542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2527543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2527543 — Surrogate Endpoint (SUR): Blood pressure
Study 25930952 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 22027666 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 19910808 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10730020 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10730020 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29688139 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15967846 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21515866 — Surrogate Endpoint (SUR): Serum sodium
Study 18246390 — Surrogate Endpoint (SUR): Serum calcium
Study 29423372 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18319306 — Surrogate Endpoint (SUR): Bone mineral density
Study 15944074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15944074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15944074 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 15944074 — Safety Biomarker (SAF): Interleukin 1
Study 10073863 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1798006 — Surrogate Endpoint (SUR): Blood pressure
Study 19605967 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17890871 — Surrogate Endpoint (SUR): Serum creatinine
Study 15388575 — Predictive Biomarker (PRD): DUSP2 mRNA
Genes: DUSP2; PAC1
Study 21189109 — Surrogate Endpoint (SUR): Bone mineral density
Study 25363381 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 11223117 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 11223117 — Safety Biomarker (SAF): DRD2
Study 21306285 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18769080 — Surrogate Endpoint (SUR): Blood pressure
Study 23155514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23155514 — Surrogate Endpoint (SUR): Bone mineral density
Study 16358163 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16358163 — Surrogate Endpoint (SUR): Blood pressure
Study 7815676 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 28399076 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25808741 — Surrogate Endpoint (SUR): Blood pressure
Study 19125855 — Surrogate Endpoint (SUR): Blood pressure
Study 19125855 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16959151 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9176747 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 3697832 — Surrogate Endpoint (SUR): Blood pressure
Study 29074964 — Surrogate Endpoint (SUR): Blood pressure
Study 834966 — Surrogate Endpoint (SUR): Serum calcium
Study 11583826 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30030480 — Surrogate Endpoint (SUR): Blood pressure
Study 23665883 — Surrogate Endpoint (SUR): Blood pressure
Study 24016546 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 18704555 — Surrogate Endpoint (SUR): Blood pressure
Study 9351616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9351616 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9351616 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9351616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21036834 — Surrogate Endpoint (SUR): Serum creatinine
Study 26003642 — Surrogate Endpoint (SUR): Serum creatinine
Study 22289020 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 10950800 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10950800 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31900843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31900843 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26139005 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23833852 — Surrogate Endpoint (SUR): Blood pressure
Study 21092287 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 16628153 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 12884193 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 29660425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27096428 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 27096428 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21846661 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 12556541 — Surrogate Endpoint (SUR): Blood pressure
Study 1653671 — Surrogate Endpoint (SUR): Blood pressure
Study 25370155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25370155 — Safety Biomarker (SAF): IL-6 and IL-10
Study 23288881 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19421684 — Surrogate Endpoint (SUR): Blood pressure
Study 19421684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12575569 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 7848794 — Surrogate Endpoint (SUR): Blood pressure
Study 3243913 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3243913 — Surrogate Endpoint (SUR): Blood pressure
Study 19319941 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 11111813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11111813 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4