TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15837835 — Safety Biomarker (SAF): Reactive oxygen species
Study 12478352 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24649525 — Surrogate Endpoint (SUR): Blood pressure
Study 2151197 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2151197 — Surrogate Endpoint (SUR): Blood pressure
Study 2151197 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20068422 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1387475 — Surrogate Endpoint (SUR): Blood pressure
Study 6381003 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15072249 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 192510 — Surrogate Endpoint (SUR): Blood pressure
Study 30341058 — Monitoring Biomarker (MOI): HBV DNA
Study 21923418 — Surrogate Endpoint (SUR): Serum sodium
Study 9514482 — Surrogate Endpoint (SUR): Blood pressure
Study 10872648 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 7589040 — Surrogate Endpoint (SUR): Blood pressure
Study 2488034 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study 21200004 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 8351163 — Surrogate Endpoint (SUR): Blood pressure
Study 3032470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 17065884 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8687515 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 31047804 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31047804 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12198327 — Surrogate Endpoint (SUR): Blood pressure
Study 6623278 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18070255 — Surrogate Endpoint (SUR): Blood pressure
Study 24576874 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24576874 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 24576874 — Safety Biomarker (SAF): Reactive oxygen species
Study 15448664 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23905373 — Predictive Biomarker (PRD): ROPN1L mRNA
Genes: ROPN1L; ASP; RSPH11
Study 23905373 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 21827677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21827677 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30557160 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 30557160 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21315844 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 16728967 — Surrogate Endpoint (SUR): Serum testosterone
Study 3215626 — Monitoring Biomarker (MOI): HBV DNA
Study 23234880 — Predictive Biomarker (PRD): CBFA2T2 mRNA
Genes: CBFA2T2; EHT; MTGR1
Study 18279104 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18279104 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3320136 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 27493100 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 27493100 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27493100 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25795699 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 23912172 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 21929671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18374755 — Surrogate Endpoint (SUR): Serum creatinine
Study 20007756 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 27448832 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18471410 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18471410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18471410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18471410 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18471410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16274095 — Surrogate Endpoint (SUR): Blood pressure
Study 31495347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21630032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21630032 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21630032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21630032 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21630032 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15153205 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28605109 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 17519305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17519305 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17519305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27029284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 24967362 — Predictive Biomarker (PRD): ATIC mRNA
Genes: ATIC; PURH; OK/SW-cl.86
Study 24967362 — Safety Biomarker (SAF): MTHFR
Study 15876311 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 10076611 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30269149 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28686775 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 23597267 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 23597267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23597267 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27208386 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 8149770 — Surrogate Endpoint (SUR): Blood pressure
Study 29733445 — Surrogate Endpoint (SUR): Blood pressure
Study 23098134 — Surrogate Endpoint (SUR): Blood pressure
Study 23098134 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23098134 — Surrogate Endpoint (SUR): Serum creatinine
Study 10028446 — Predictive Biomarker (PRD): MUC6 mRNA
Genes: MUC6
Study 10028446 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 10028446 — Predictive Biomarker (PRD): MUC4 mRNA
Genes: MUC4
Study 10028446 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study 31839533 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 30632692 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17898501 — Surrogate Endpoint (SUR): Blood pressure
Study 17898501 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 17898501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15483801 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25684089 — Surrogate Endpoint (SUR): Blood pressure
Study 25684089 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25684089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 4018464 — Surrogate Endpoint (SUR): Blood pressure
Study 26667403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26667403 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26667403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24218006 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 24218006 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 24218006 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 24218006 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24218006 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 24218006 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20660832 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 28641496 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27146258 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 24661355 — Surrogate Endpoint (SUR): Blood pressure
Study 20350694 — Surrogate Endpoint (SUR): Blood pressure
Study 25820048 — Surrogate Endpoint (SUR): Blood pressure
Study 29515256 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 22694757 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20555311 — Surrogate Endpoint (SUR): Blood pressure
Study 15914352 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12887344 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 8450527 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8450527 — Surrogate Endpoint (SUR): Blood pressure
Study 27595688 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16154196 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31236938 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 31236938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31236938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25024396 — Surrogate Endpoint (SUR): Blood pressure
Study 22319035 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22319035 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10890377 — Safety Biomarker (SAF): IL-6 and IL-10
Study 6397516 — Surrogate Endpoint (SUR): Blood pressure
Study 16079312 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9509976 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9509976 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 2687194 — Surrogate Endpoint (SUR): Blood pressure
Study 23660095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23660095 — Monitoring Biomarker (MOI): Procalcitonin
Study 18200818 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18200818 — Surrogate Endpoint (SUR): Blood pressure
Study 9744695 — Surrogate Endpoint (SUR): Blood pressure
Study 26386123 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 26386123 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26386123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26386123 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26386123 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 19201576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1716790 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1716790 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27161620 — Surrogate Endpoint (SUR): Blood pressure
Study 12560434 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7064898 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 27064996 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11821078 — Surrogate Endpoint (SUR): Sperm parameters
Study 1364129 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30392753 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 18245541 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18245541 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18245541 — Safety Biomarker (SAF): Human leucocyte antigen
Study 16476069 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 16736996 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3144329 — Surrogate Endpoint (SUR): Blood pressure
Study 30475967 — Safety Biomarker (SAF): Reactive oxygen species
Study 14560325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14560325 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8774818 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30880909 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20195400 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20195400 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16298658 — Surrogate Endpoint (SUR): Serum creatinine
Study 16298658 — Surrogate Endpoint (SUR): Blood pressure
Study 31400337 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 12771114 — Surrogate Endpoint (SUR): Blood pressure
Study 12771114 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10720165 — Surrogate Endpoint (SUR): Blood pressure
Study 30276476 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 30276476 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 12474023 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 7750331 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 2274996 — Surrogate Endpoint (SUR): Serum calcium
Study 2274996 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21455075 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16012177 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 16012177 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 7380993 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 24854628 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 24854628 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16633363 — Predictive Biomarker (PRD): Hormone receptor
Study 12941199 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 10532418 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10532418 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 8983318 — Surrogate Endpoint (SUR): Blood pressure
Study 1953228 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1953228 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11281234 — Surrogate Endpoint (SUR): Blood pressure
Study 3108131 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3108131 — Surrogate Endpoint (SUR): Blood pressure
Study 27914297 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 3038423 — Surrogate Endpoint (SUR): Blood pressure
Study 27069153 — Predictive Biomarker (PRD): SLC11A1 mRNA
Genes: SLC11A1; LSH; NRAMP; NRAMP1
Study 23733528 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 16548361 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8751803 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27100432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27100432 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27100432 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20730395 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17574466 — Surrogate Endpoint (SUR): Bone mineral density
Study 10441825 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 2126002 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19620930 — Surrogate Endpoint (SUR): Blood pressure
Study 17225141 — Surrogate Endpoint (SUR): Blood pressure
Study 8484505 — Surrogate Endpoint (SUR): Blood pressure
Study 25933364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25933364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10642712 — Surrogate Endpoint (SUR): Blood pressure
Study 8157045 — Surrogate Endpoint (SUR): Serum potassium
Study 28343601 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28343601 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28343601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28343601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28343601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19422296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17174632 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11731184 — Surrogate Endpoint (SUR): Bone mineral density
Study 7633974 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7633974 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2585215 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2585215 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 31105976 — Surrogate Endpoint (SUR): Blood pressure
Study 21492183 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 21492183 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 15159270 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15159270 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9544237 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7541325 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30239116 — Surrogate Endpoint (SUR): Bone mineral density
Study 24011382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24011382 — Surrogate Endpoint (SUR): Blood pressure
Study 17407633 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9506004 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22137497 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22137497 — Surrogate Endpoint (SUR): Blood pressure
Study 18260178 — Surrogate Endpoint (SUR): Bone mineral density
Study 29703414 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27396428 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 22311411 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 22311411 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 22311411 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 27642057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27642057 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20195844 — Surrogate Endpoint (SUR): Bone mineral density
Study 19439506 — Predictive Biomarker (PRD): SLC16A2 mRNA
Genes: SLC16A2; MCT7; MCT8; XPCT
Study 19439506 — Predictive Biomarker (PRD): SLC16A10 mRNA
Genes: SLC16A10; MCT10; TAT1
Study 25643790 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 25643790 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25643790 — Surrogate Endpoint (SUR): Serum creatinine
Study 25643790 — Surrogate Endpoint (SUR): Blood pressure
Study 17161769 — Surrogate Endpoint (SUR): Blood pressure
Study 17161769 — Surrogate Endpoint (SUR): Serum creatinine
Study 3370132 — Surrogate Endpoint (SUR): Blood pressure
Study 30607000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30607000 — Safety Biomarker (SAF): Cytochrome c
Study 25347968 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 25347968 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 25347968 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19027013 — Monitoring Biomarker (MOI): HBV DNA
Study 17585971 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 1673233 — Surrogate Endpoint (SUR): Blood pressure
Study 6811068 — Surrogate Endpoint (SUR): Blood pressure
Study 18612923 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 18612923 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 18612923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11847165 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11847165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2