TrialPanorama/TrialPanorama-database huggingface dataset:
Study 6110954 — Surrogate Endpoint (SUR): Blood pressure
Study 6110954 — Surrogate Endpoint (SUR): Serum potassium
Study 31425383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31425383 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 22093930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16788707 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28371811 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 28371811 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 18289903 — Surrogate Endpoint (SUR): Blood pressure
Study 18289903 — Surrogate Endpoint (SUR): Bone mineral density
Study 17294991 — Surrogate Endpoint (SUR): Blood pressure
Study 31122893 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7758054 — Surrogate Endpoint (SUR): Blood pressure
Study 28905108 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18950736 — Surrogate Endpoint (SUR): Bone mineral density
Study 17299073 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15203552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15203552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15203552 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15203552 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11593074 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 25671925 — Surrogate Endpoint (SUR): Blood pressure
Study 24231018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12668989 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 10376778 — Surrogate Endpoint (SUR): Blood pressure
Study 29929610 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28403850 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28403850 — Surrogate Endpoint (SUR): Blood pressure
Study 17509689 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17509689 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17509689 — Surrogate Endpoint (SUR): Blood pressure
Study 30951501 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 30951501 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 30951501 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30951501 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 30951501 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30951501 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 30951501 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 11226652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24958738 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 24958738 — Safety Biomarker (SAF): miR-214
Genes: MIR214
Study 19640511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19640511 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 24064695 — Surrogate Endpoint (SUR): Serum calcium
Study 8896479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25259747 — Surrogate Endpoint (SUR): Blood pressure
Study 25259747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22959763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16079222 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 16079222 — Surrogate Endpoint (SUR): Blood pressure
Study 20009091 — Surrogate Endpoint (SUR): Blood pressure
Study 31610637 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31610637 — Surrogate Endpoint (SUR): Serum testosterone
Study 24092475 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22331346 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22331346 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20591628 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 20591628 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study 24452943 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24452943 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24452943 — Surrogate Endpoint (SUR): Blood pressure
Study 24791969 — Surrogate Endpoint (SUR): Blood pressure
Study 31634193 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 31264761 — Surrogate Endpoint (SUR): Blood pressure
Study 16581549 — Surrogate Endpoint (SUR): Blood pressure
Study 8839903 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9972889 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 2651767 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31276981 — Predictive Biomarker (PRD): Hormone receptor
Study 16682611 — Surrogate Endpoint (SUR): Blood pressure
Study 27460675 — Surrogate Endpoint (SUR): Blood pressure
Study 21077043 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 15772062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10048679 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2289214 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27624622 — Surrogate Endpoint (SUR): Blood pressure
Study 20682612 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 20682612 — Surrogate Endpoint (SUR): Serum creatinine
Study 15146410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15146410 — Safety Biomarker (SAF): Interleukin 1
Study 9408807 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31972315 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 31972315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23850070 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 20504165 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20504165 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 9289428 — Surrogate Endpoint (SUR): Blood pressure
Study 17413839 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9644639 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28399844 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28399844 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28399844 — Surrogate Endpoint (SUR): Blood pressure
Study 9663825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9663825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9663825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25842461 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10081852 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 2349137 — Surrogate Endpoint (SUR): Blood pressure
Study 24050737 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19338151 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19338151 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27384328 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 26175332 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 21196426 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 21196426 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22819275 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20546545 — Surrogate Endpoint (SUR): Bone mineral density
Study 15823625 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15823625 — Surrogate Endpoint (SUR): Blood pressure
Study 7738683 — Surrogate Endpoint (SUR): Bone mineral density
Study 11732862 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11732862 — Safety Biomarker (SAF): Interleukin 12
Study 11732862 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 26764260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22542362 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 22542362 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18317625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18317625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16046191 — Surrogate Endpoint (SUR): Blood pressure
Study 7793116 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7344590 — Surrogate Endpoint (SUR): Blood pressure
Study 22584195 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 24667714 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24667714 — Predictive Biomarker (PRD): Hormone receptor
Study 9285079 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 15159414 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 7842354 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 10480346 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24176449 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9241341 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17008408 — Predictive Biomarker (PRD): PDE9A mRNA
Genes: PDE9A
Study 17008408 — Predictive Biomarker (PRD): PDE11A mRNA
Genes: PDE11A
Study 17008408 — Predictive Biomarker (PRD): PDE1A mRNA
Genes: PDE1A
Study 25422488 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25422488 — Predictive Biomarker (PRD): Hormone receptor
Study 23829417 — Surrogate Endpoint (SUR): Blood pressure
Study 17552046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17552046 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11841770 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10682564 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10682564 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2243264 — Surrogate Endpoint (SUR): Blood pressure
Study 8092223 — Surrogate Endpoint (SUR): Blood pressure
Study 29804360 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28243834 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 28243834 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 9176035 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9176035 — Surrogate Endpoint (SUR): Blood pressure
Study 19397474 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19397474 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19397474 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7862712 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7862712 — Surrogate Endpoint (SUR): Blood pressure
Study 25901093 — Surrogate Endpoint (SUR): Blood pressure
Study 20957631 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18033629 — Surrogate Endpoint (SUR): Bone mineral density
Study 9408932 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 2878746 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 2878746 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30229999 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 31277053 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 29062346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25810066 — Surrogate Endpoint (SUR): Blood pressure
Study 24044618 — Surrogate Endpoint (SUR): Blood pressure
Study 24044618 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24044618 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31642426 — Surrogate Endpoint (SUR): Serum creatinine
Study 23766446 — Surrogate Endpoint (SUR): Blood pressure
Study 16824157 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16824157 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16824157 — Surrogate Endpoint (SUR): Serum creatinine
Study 9330125 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29239515 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19231908 — Surrogate Endpoint (SUR): Blood pressure
Study 8897078 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26077874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26077874 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 25375279 — Surrogate Endpoint (SUR): Blood pressure
Study 31425453 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12575970 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12575970 — Surrogate Endpoint (SUR): Blood pressure
Study 9605680 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9990211 — Surrogate Endpoint (SUR): Blood pressure
Study 23756425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23756425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20058594 — Surrogate Endpoint (SUR): Blood pressure
Study 26258571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26258571 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3288801 — Surrogate Endpoint (SUR): Blood pressure
Study 25924841 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25924841 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 23588194 — Surrogate Endpoint (SUR): Serum uric acid
Study 17604500 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15366593 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7981002 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 18055296 — Surrogate Endpoint (SUR): Blood pressure
Study 16086927 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12163792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12163792 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10473964 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 2257858 — Surrogate Endpoint (SUR): Blood pressure
Study 2959967 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 3829582 — Surrogate Endpoint (SUR): Blood pressure
Study 24929428 — Surrogate Endpoint (SUR): Blood pressure
Study 28246884 — Surrogate Endpoint (SUR): Bone mineral density
Study 11752031 — Surrogate Endpoint (SUR): Serum creatinine
Study 18611068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16025962 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26039019 — Safety Biomarker (SAF): Reactive oxygen species
Study 15047679 — Surrogate Endpoint (SUR): Blood pressure
Study 7740961 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31899315 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31899315 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 19124845 — Surrogate Endpoint (SUR): Blood pressure
Study 30514262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30514262 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30514262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 30514262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 12433892 — Surrogate Endpoint (SUR): Blood pressure
Study 7479225 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 31999753 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31487627 — Surrogate Endpoint (SUR): Blood pressure
Study 27689735 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 20022264 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20022264 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 20022264 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20022264 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 29254080 — Surrogate Endpoint (SUR): Blood pressure
Study 19056642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19056642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19056642 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9405728 — Surrogate Endpoint (SUR): Bone mineral density
Study 7043395 — Surrogate Endpoint (SUR): Blood pressure
Study 29189585 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22101697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22101697 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19346990 — Surrogate Endpoint (SUR): Serum creatinine
Study 15361940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15361940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15361940 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17302251 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9437183 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9437183 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31935197 — Predictive Biomarker (PRD): S1PR1 mRNA
Genes: S1PR1; CHEDG1; EDG1
Study 31935197 — Predictive Biomarker (PRD): S1PR5 mRNA
Genes: S1PR5; EDG8
Study 31935197 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31935197 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 29773827 — Predictive Biomarker (PRD): HCN4 mRNA
Genes: HCN4
Study 7488279 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15062883 — Surrogate Endpoint (SUR): Blood pressure
Study 23709323 — Predictive Biomarker (PRD): MSN mRNA
Genes: MSN
Study 19329546 — Surrogate Endpoint (SUR): Blood pressure
Study 2993946 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29982627 — Surrogate Endpoint (SUR): Blood pressure
Study 26453639 — Predictive Biomarker (PRD): DMRTA1 mRNA
Genes: DMRTA1; DMO
Study 22587616 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 22587616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1769141 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 25934661 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17969902 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17969902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17969902 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11889008 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11889008 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10437863 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10437863 — Surrogate Endpoint (SUR): Serum creatinine
Study 10437863 — Surrogate Endpoint (SUR): Blood pressure
Study 30741025 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 25740863 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 22606361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16047554 — Surrogate Endpoint (SUR): Blood pressure
Study 2317162 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24952307 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 23117550 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23117550 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 18728909 — Surrogate Endpoint (SUR): Blood pressure
Study 11044578 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 25741456 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 22574591 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 22574591 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B