TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24458439 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 24458439 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 24458439 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study 24458439 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 16019102 — Surrogate Endpoint (SUR): Blood pressure
Study 10848718 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 2878130 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 14749744 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29316715 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21070720 — Surrogate Endpoint (SUR): Blood pressure
Study 21070720 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9361342 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 3513564 — Surrogate Endpoint (SUR): Blood pressure
Study 31655485 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27508274 — Predictive Biomarker (PRD): SECTM1 mRNA
Genes: SECTM1; K12
Study 24691452 — Surrogate Endpoint (SUR): Blood pressure
Study 22455564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22455564 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 22455564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15824294 — Surrogate Endpoint (SUR): Blood pressure
Study 12854895 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 31323685 — Safety Biomarker (SAF): Reactive oxygen species
Study 31323685 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24346155 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 24346155 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24346155 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 24346155 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 24346155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21685819 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19614721 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 19614721 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12625668 — Surrogate Endpoint (SUR): Blood pressure
Study 24864045 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22266895 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 7741785 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study 19681418 — Surrogate Endpoint (SUR): Blood pressure
Study 16385545 — Surrogate Endpoint (SUR): Blood pressure
Study 8866535 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 31507054 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19447919 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19447919 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 9753020 — Surrogate Endpoint (SUR): Serum creatinine
Study 30430209 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 25223267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25223267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25223267 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17642233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10206720 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 2360502 — Surrogate Endpoint (SUR): Blood pressure
Study 22030577 — Surrogate Endpoint (SUR): Blood pressure
Study 18672290 — Surrogate Endpoint (SUR): Blood pressure
Study 12694213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18794543 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7033745 — Surrogate Endpoint (SUR): Blood pressure
Study 31805992 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 26372274 — Predictive Biomarker (PRD): KLF2 mRNA
Genes: KLF2; LKLF
Study 26372274 — Predictive Biomarker (PRD): KLF4 mRNA
Genes: KLF4; EZF; GKLF
Study 23401474 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 23401474 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23401474 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23401474 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 23401474 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20396722 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 7822629 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 2900819 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20503809 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15189747 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 30105357 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 30105357 — Predictive Biomarker (PRD): RIT1 mRNA
Genes: RIT1; RIBB; RIT; ROC1
Study 12845340 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12845340 — Surrogate Endpoint (SUR): Blood pressure
Study 22147942 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 22147942 — Predictive Biomarker (PRD): Microsatellite instability
Study 19124372 — Surrogate Endpoint (SUR): Serum potassium
Study 10556133 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 10556133 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 10556133 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 6711997 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29982658 — Surrogate Endpoint (SUR): Blood pressure
Study 26907728 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 23137805 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 12584832 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12584832 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 12584832 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24885178 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 24885178 — Surrogate Endpoint (SUR): Blood pressure
Study 8780536 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 1600965 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 6389233 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31330804 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30126458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22295934 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22295934 — Surrogate Endpoint (SUR): Serum creatinine
Study 9735391 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8903669 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8903669 — Surrogate Endpoint (SUR): Blood pressure
Study 7630678 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28601388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 17341993 — Surrogate Endpoint (SUR): Blood pressure
Study 20404311 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20404311 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15976804 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26062182 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 18341671 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7522629 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 7522629 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31356262 — Surrogate Endpoint (SUR): Blood pressure
Study 21420888 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16940217 — Surrogate Endpoint (SUR): Blood pressure
Study 14572169 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 9106924 — Safety Biomarker (SAF): Hyaluronic acid
Study 26620496 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 17653058 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17653058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17653058 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17653058 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28005265 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 24814500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16620136 — Surrogate Endpoint (SUR): Blood pressure
Study 10979160 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19898595 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15557008 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2080948 — Surrogate Endpoint (SUR): Blood pressure
Study 9284850 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29113986 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 27827328 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 24726142 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24726142 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15882229 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7740570 — Surrogate Endpoint (SUR): Blood pressure
Study 1668907 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24894685 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22574612 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 22574612 — Surrogate Endpoint (SUR): Blood pressure
Study 18981326 — Surrogate Endpoint (SUR): Serum potassium
Study 10379633 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10379633 — Surrogate Endpoint (SUR): Blood pressure
Study 6499895 — Predictive Biomarker (PRD): MOXD1 mRNA
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 6499895 — Surrogate Endpoint (SUR): Blood pressure
Study 26984105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20506371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18336547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16116971 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1925820 — Surrogate Endpoint (SUR): Blood pressure
Study 25144133 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 11288792 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 25853877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24043457 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31077596 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31077596 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 31077596 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 31077596 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 31077596 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 31077596 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 31077596 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 19333948 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19333948 — Surrogate Endpoint (SUR): Serum creatinine
Study 19333948 — Surrogate Endpoint (SUR): Blood pressure
Study 16906265 — Surrogate Endpoint (SUR): Blood pressure
Study 9015657 — Surrogate Endpoint (SUR): Blood pressure
Study 22608892 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 18417083 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12212127 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 12212127 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 21996239 — Predictive Biomarker (PRD): RAB8A mRNA
Genes: RAB8A; MEL; RAB8
Study 14519140 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29685141 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 26151494 — Surrogate Endpoint (SUR): Blood pressure
Study 20436517 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 20436517 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20436517 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18360781 — Surrogate Endpoint (SUR): Blood pressure
Study 29766651 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 16216530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16216530 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16216530 — Surrogate Endpoint (SUR): Serum testosterone
Study 4025853 — Surrogate Endpoint (SUR): Blood pressure
Study 31290696 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31499457 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 19213680 — Surrogate Endpoint (SUR): Serum creatinine
Study 30615795 — Surrogate Endpoint (SUR): Blood pressure
Study 17334380 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 17334380 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15869770 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 12539108 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 31818636 — Safety Biomarker (SAF): IL-6 and IL-10
Study 30816066 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30816066 — Safety Biomarker (SAF): BDNF
Study 19624554 — Predictive Biomarker (PRD): EDAR mRNA
Genes: EDAR; DL
Study 18179991 — Surrogate Endpoint (SUR): Bone mineral density
Study 18179991 — Surrogate Endpoint (SUR): Serum calcium
Study 29280483 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 19636975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19636975 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 12428232 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21723131 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16842029 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 12970782 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 12970782 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 20924215 — Monitoring Biomarker (MOI): HBV DNA
Study 16084873 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 2146040 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 219471 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 219471 — Surrogate Endpoint (SUR): Blood pressure
Study 30731195 — Monitoring Biomarker (MOI): HBV DNA
Study 30243062 — Surrogate Endpoint (SUR): Blood pressure
Study 26174080 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 11807630 — Surrogate Endpoint (SUR): Hematologic response
Study 19010347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19010347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19010347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2522134 — Surrogate Endpoint (SUR): Blood pressure
Study 25044345 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21591986 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12619027 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 8626096 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22574590 — Surrogate Endpoint (SUR): Serum creatinine
Study 22574590 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22574590 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22574590 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8638531 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29178434 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 27495085 — Monitoring Biomarker (MOI): HBV DNA
Study 23103485 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 18341655 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18341655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18341655 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 18341655 — Safety Biomarker (SAF): BDNF
Study 27495190 — Surrogate Endpoint (SUR): Blood pressure
Study 31283865 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28801393 — Surrogate Endpoint (SUR): Blood pressure
Study 17173662 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17173662 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22169130 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22169130 — Surrogate Endpoint (SUR): Blood pressure
Study 15677511 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 15677511 — Surrogate Endpoint (SUR): Blood pressure
Study 15677511 — Surrogate Endpoint (SUR): Serum creatinine
Study 9106790 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 31298466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29362795 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 25594166 — Surrogate Endpoint (SUR): Blood pressure
Study 22406434 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22406434 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 22406434 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 28652968 — Predictive Biomarker (PRD): ITLN1 mRNA
Genes: ITLN1; INTL; ITLN; LFR; UNQ640/PRO1270
Study 23242843 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17877128 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 18335515 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10404825 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 10404825 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17275896 — Surrogate Endpoint (SUR): Blood pressure
Study 22997073 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8116352 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9531581 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28823927 — Surrogate Endpoint (SUR): Blood pressure
Study 25624429 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11434728 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9700035 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18571850 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 16020915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16197815 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 16197815 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7747709 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 6117684 — Surrogate Endpoint (SUR): Blood pressure
Study 23645692 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23645692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23645692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9688002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 6356903 — Surrogate Endpoint (SUR): Blood pressure
Study 15819974 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26468213 — Surrogate Endpoint (SUR): Blood pressure
Study 18507270 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18507270 — Surrogate Endpoint (SUR): Blood pressure
Study 1499364 — Surrogate Endpoint (SUR): Blood pressure
Study 22751085 — Safety Biomarker (SAF): DRD2
Study 15598680 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7639218 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 29211953 — Surrogate Endpoint (SUR): Bacterial count
Study 20537748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20537748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25516625 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20829521 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 12867222 — Surrogate Endpoint (SUR): Blood pressure
Study 8705639 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8705639 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8705639 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31771589 — Surrogate Endpoint (SUR): Blood pressure
Study 17693150 — Surrogate Endpoint (SUR): Bone mineral density
Study 15536539 — Surrogate Endpoint (SUR): Bone mineral density
Study 25393080 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15650984 — Surrogate Endpoint (SUR): Serum creatinine
Study 11786584 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9538979 — Surrogate Endpoint (SUR): Blood pressure
Study 31828863 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23239836 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP