TrialPanorama/TrialPanorama-database huggingface dataset:
Study 709214 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 709214 — Surrogate Endpoint (SUR): Blood pressure
Study 15036490 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 15036490 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11804247 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2820619 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2820619 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 17432681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17432681 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21846460 — Surrogate Endpoint (SUR): Probing pocket depth
Study 2675953 — Surrogate Endpoint (SUR): Blood pressure
Study 28368334 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 23327614 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20137328 — Surrogate Endpoint (SUR): Blood pressure
Study 16446323 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16446323 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16446323 — Surrogate Endpoint (SUR): Blood pressure
Study 2838926 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31563369 — Predictive Biomarker (PRD): GRAP2 mRNA
Genes: GRAP2; GADS; GRB2L; GRID
Study 28315878 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28315878 — Surrogate Endpoint (SUR): Serum creatinine
Study 26165736 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 21943845 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11024378 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 8147235 — Surrogate Endpoint (SUR): Blood pressure
Study 3310563 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26846612 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 25902813 — Surrogate Endpoint (SUR): Serum potassium
Study 16552410 — Surrogate Endpoint (SUR): Blood pressure
Study 30089602 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30089602 — Predictive Biomarker (PRD): Hormone receptor
Study 30089602 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30605991 — Surrogate Endpoint (SUR): Blood pressure
Study 25955760 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 30664895 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30664895 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 28612123 — Safety Biomarker (SAF): Reactive oxygen species
Study 19486077 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16289980 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 6100870 — Surrogate Endpoint (SUR): Blood pressure
Study 20190538 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 16507379 — Surrogate Endpoint (SUR): Blood pressure
Study 31368269 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 31368269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23835673 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17464696 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 1280737 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1280737 — Surrogate Endpoint (SUR): Blood pressure
Study 24472331 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 20081109 — Surrogate Endpoint (SUR): Blood pressure
Study 11867385 — Surrogate Endpoint (SUR): Blood pressure
Study 1973387 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28603468 — Predictive Biomarker (PRD): SLC7A5 mRNA
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study 28603468 — Predictive Biomarker (PRD): SLC36A1 mRNA
Genes: SLC36A1; PAT1
Study 28603468 — Predictive Biomarker (PRD): SLC7A1 mRNA
Genes: SLC7A1; ATRC1; ERR; REC1L
Study 28603468 — Predictive Biomarker (PRD): SLC38A2 mRNA
Genes: SLC38A2; ATA2; KIAA1382; SAT2; SNAT2
Study 21723567 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21723567 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 21723567 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 21723567 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 16801663 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16801663 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10946892 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 1457767 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1457767 — Surrogate Endpoint (SUR): Serum creatinine
Study 1457767 — Surrogate Endpoint (SUR): Blood pressure
Study 19011778 — Safety Biomarker (SAF): Urinary microalbumin
Study 19011778 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10676669 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9424647 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 21473794 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 21473794 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 30092666 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 23635803 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 23635803 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 23635803 — Safety Biomarker (SAF): DRD2
Study 12547874 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 9024712 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 25636895 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 9453332 — Surrogate Endpoint (SUR): Blood pressure
Study 26754586 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26754586 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26754586 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1642678 — Surrogate Endpoint (SUR): Blood pressure
Study 29609594 — Surrogate Endpoint (SUR): Blood pressure
Study 23770971 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16883902 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 10029562 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10029562 — Surrogate Endpoint (SUR): Blood pressure
Study 22821790 — Surrogate Endpoint (SUR): Blood pressure
Study 18077778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15895892 — Safety Biomarker (SAF): Hyaluronic acid
Study 8983276 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16249547 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11844826 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11844826 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16734552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DMRT1 mRNA
Genes: DMRT1; DMT1
Study 12617377 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 12617377 — Surrogate Endpoint (SUR): Blood pressure
Study 7903572 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2423408 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 7531023 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23649964 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study 22191234 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22191234 — Predictive Biomarker (PRD): EPHB2 mRNA
Genes: EPHB2; DRT; EPHT3; EPTH3; ERK; HEK5; TYRO5
Study 22191234 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 15284252 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 7872447 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31842026 — Surrogate Endpoint (SUR): Blood pressure
Study 23644928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23644928 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 16001181 — Surrogate Endpoint (SUR): Bone mineral density
Study 11746532 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11746532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11746532 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 7534945 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12970225 — Surrogate Endpoint (SUR): Blood pressure
Study 19459810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17325603 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17325603 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11449531 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 11449531 — Surrogate Endpoint (SUR): Serum calcium
Study 9684692 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 7511495 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 7511495 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7511495 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23889803 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23889803 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20052461 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 14664167 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 14664167 — Surrogate Endpoint (SUR): Blood pressure
Study 1338389 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 30257036 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 27322462 — Predictive Biomarker (PRD): UBE2C mRNA
Genes: UBE2C; UBCH10
Study 27322462 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A2 mRNA
Genes: SRD5A2
Study 27322462 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27322462 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27322462 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 24224738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17700289 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 16432644 — Surrogate Endpoint (SUR): Bone mineral density
Study 6142348 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6142348 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25380077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23187951 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17023253 — Predictive Biomarker (PRD): RNPEP mRNA
Genes: RNPEP; APB
Study 9854457 — Surrogate Endpoint (SUR): Blood pressure
Study 22982183 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 16118771 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16118771 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7658874 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7658874 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2541741 — Surrogate Endpoint (SUR): Blood pressure
Study 22689129 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28273028 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 28273028 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 25542520 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25542520 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11707740 — Surrogate Endpoint (SUR): Serum calcium
Study 11707740 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 11548230 — Surrogate Endpoint (SUR): Bone mineral density
Study 25470096 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 20655180 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20655180 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 18240288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18240288 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18240288 — Safety Biomarker (SAF): BDNF
Study 27362935 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 27362935 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study 27362935 — Safety Biomarker (SAF): Reactive oxygen species
Study 22264575 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22264575 — Surrogate Endpoint (SUR): Blood pressure
Study 17372173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17372173 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2490928 — Surrogate Endpoint (SUR): Bacterial count
Study 776350 — Surrogate Endpoint (SUR): Blood pressure
Study 30905211 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31331193 — Predictive Biomarker (PRD): ADCY9 mRNA
Genes: ADCY9; KIAA0520
Study 31331193 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 21865363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11498263 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9711427 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8040675 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24632426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11966672 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 28336284 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17332612 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 17332612 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 9468365 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8521898 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29098740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29098740 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 23760223 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19593208 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 19593208 — Surrogate Endpoint (SUR): Blood pressure
Study 147656 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 147656 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 12469457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12469457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12469457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31085131 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23327028 — Surrogate Endpoint (SUR): Blood pressure
Study 19808268 — Surrogate Endpoint (SUR): Blood pressure
Study 17722957 — Predictive Biomarker (PRD): BCL2L1 mRNA
Genes: BCL2L1; BCL2L; BCLX
Study 17722957 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 7998586 — Surrogate Endpoint (SUR): Blood pressure
Study 7998586 — Surrogate Endpoint (SUR): Serum potassium
Study 28430748 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22843041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11134125 — Surrogate Endpoint (SUR): Blood pressure
Study 9481970 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9481970 — Surrogate Endpoint (SUR): Blood pressure
Study 29458053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29458053 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 21122270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16732903 — Monitoring Biomarker (MOI): HBV DNA
Study 12079904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8589769 — Surrogate Endpoint (SUR): Blood pressure
Study 2162877 — Surrogate Endpoint (SUR): Blood pressure
Study 27007989 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27007989 — Surrogate Endpoint (SUR): Serum calcium
Study 16301884 — Surrogate Endpoint (SUR): Blood pressure
Study 11896441 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 2533582 — Surrogate Endpoint (SUR): Blood pressure
Study 342627 — Safety Biomarker (SAF): Preexisting antibody
Study 31096775 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 23616126 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 12473554 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7707809 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7707809 — Surrogate Endpoint (SUR): Blood pressure
Study 26574625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24297579 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 3553478 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study 3553478 — Surrogate Endpoint (SUR): Blood pressure
Study 24124358 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 20377577 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1581404 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 3878682 — Surrogate Endpoint (SUR): Serum potassium
Study 17631074 — Surrogate Endpoint (SUR): Blood pressure
Study 17631074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17631074 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16133688 — Surrogate Endpoint (SUR): Bone mineral density
Study 7669374 — Surrogate Endpoint (SUR): Blood pressure
Study 26912209 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11897643 — Surrogate Endpoint (SUR): Blood pressure
Study 10193670 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2268940 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7040142 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7999599 — Surrogate Endpoint (SUR): Serum calcium
Study 10690937 — Predictive Biomarker (PRD): GCSAM mRNA
Genes: GCSAM; GAL; GCET2
Study 10690937 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 10488967 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28381584 — Surrogate Endpoint (SUR): Blood pressure
Study 17261336 — Surrogate Endpoint (SUR): Blood pressure
Study 17261336 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14692040 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 7542109 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 14727010 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 14727010 — Surrogate Endpoint (SUR): Bone mineral density
Study 11758675 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 31487797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31487797 — Surrogate Endpoint (SUR): Blood pressure
Study 26025412 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 14634679 — Surrogate Endpoint (SUR): Blood pressure
Study 14634679 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1627372 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9220520 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8427515 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 18291017 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16188911 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 18360062 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16789979 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16789979 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16789979 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22294639 — Safety Biomarker (SAF): Hyaluronic acid
Study 15958361 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19237811 — Surrogate Endpoint (SUR): Serum creatinine
Study 16236942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16236942 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16236942 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 2316014 — Surrogate Endpoint (SUR): Blood pressure
Study 19325138 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15916851 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17294139 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17294139 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2226538 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 374444 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28625256 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28625256 — Surrogate Endpoint (SUR): Serum creatinine
Study 25736441 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB