TrialPanorama/TrialPanorama-database huggingface dataset:
Study 3828253 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28330808 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28330808 — Predictive Biomarker (PRD): LOXL2 mRNA
Genes: LOXL2
Study 28330808 — Predictive Biomarker (PRD): SH3GL2 mRNA
Genes: SH3GL2; CNSA2; SH3D2A
Study 28330808 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 21192149 — Surrogate Endpoint (SUR): Blood pressure
Study 18629368 — Surrogate Endpoint (SUR): Blood pressure
Study 18629368 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30764769 — Monitoring Biomarker (MOI): Procalcitonin
Study 30764769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26983390 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 28285432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28285432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23613788 — Monitoring Biomarker (MOI): HBV DNA
Study 19065892 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 29053981 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 29927211 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 12791629 — Surrogate Endpoint (SUR): Blood pressure
Study 30580130 — Surrogate Endpoint (SUR): Serum creatinine
Study 8848938 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 202160 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21821865 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 15226168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9683924 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 9683924 — Predictive Biomarker (PRD): REN mRNA
Genes: REN
Study 7706607 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29852873 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26515417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26515417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26515417 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21769759 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15298564 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 15298564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15298564 — Safety Biomarker (SAF): IL-6 and IL-10
Study 25422247 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 22500884 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 22500884 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22500884 — Surrogate Endpoint (SUR): Serum testosterone
Study 17623816 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17623816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28637670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25873155 — Surrogate Endpoint (SUR): Blood pressure
Study 24060993 — Surrogate Endpoint (SUR): Blood pressure
Study 21355145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21355145 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21355145 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12453861 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9658748 — Safety Biomarker (SAF): Interleukin 1
Study 9658748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31315885 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20416137 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 12482009 — Surrogate Endpoint (SUR): Blood pressure
Study 26413574 — Safety Biomarker (SAF): Reactive oxygen species
Study 23432431 — Predictive Biomarker (PRD): Chromosome 17p
Study 19917449 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17912226 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7036726 — Surrogate Endpoint (SUR): Blood pressure
Study 9186348 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20703256 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 20703256 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 30932951 — Surrogate Endpoint (SUR): Serum creatinine
Study 30932951 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 24102369 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 18687167 — Predictive Biomarker (PRD): FDPS mRNA
Genes: FDPS; FPS; KIAA1293
Study 18687167 — Surrogate Endpoint (SUR): Bone mineral density
Study 11954988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10981547 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10981547 — Surrogate Endpoint (SUR): Serum creatinine
Study 10981547 — Surrogate Endpoint (SUR): Blood pressure
Study 10981547 — Surrogate Endpoint (SUR): Serum potassium
Study 19796455 — Surrogate Endpoint (SUR): Serum testosterone
Study 12700715 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 11041569 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23398493 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18836357 — Predictive Biomarker (PRD): IDE mRNA
Genes: IDE
Study 14520605 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2586439 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19282610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11943102 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 9649995 — Surrogate Endpoint (SUR): Blood pressure
Study 2382949 — Surrogate Endpoint (SUR): Blood pressure
Study 31922355 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31922355 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 31922355 — Surrogate Endpoint (SUR): Blood pressure
Study 18754021 — Surrogate Endpoint (SUR): Blood pressure
Study 1818806 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 1818806 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6651994 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19874436 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21409494 — Surrogate Endpoint (SUR): Serum sodium
Study 21409494 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8667198 — Surrogate Endpoint (SUR): Blood pressure
Study 30952795 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 21920484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15880336 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15880336 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28514264 — Surrogate Endpoint (SUR): Blood pressure
Study 21677600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21677600 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16380823 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 16380823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22425702 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 20223877 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 18314182 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18672767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16823584 — Surrogate Endpoint (SUR): Blood pressure
Study 12791633 — Surrogate Endpoint (SUR): Bone mineral density
Study 31099911 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31099911 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study 31099911 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 21848509 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 20094043 — Surrogate Endpoint (SUR): Blood pressure
Study 15241837 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 21233606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21233606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21233606 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17317751 — Surrogate Endpoint (SUR): Blood pressure
Study 7893585 — Predictive Biomarker (PRD): CLN3 mRNA
Genes: CLN3; BTS
Study 2822795 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2822795 — Surrogate Endpoint (SUR): Blood pressure
Study 29028776 — Surrogate Endpoint (SUR): Blood pressure
Study 25589191 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20930640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20930640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20930640 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15213043 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2528405 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2528405 — Surrogate Endpoint (SUR): Blood pressure
Study 31980638 — Surrogate Endpoint (SUR): Blood pressure
Study 31152598 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 31152598 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28939406 — Surrogate Endpoint (SUR): Blood pressure
Study 26154787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21194255 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21194255 — Surrogate Endpoint (SUR): Serum creatinine
Study 16504646 — Surrogate Endpoint (SUR): Blood pressure
Study 2426997 — Surrogate Endpoint (SUR): Blood pressure
Study 19447770 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17851890 — Surrogate Endpoint (SUR): Pathological complete response
Study 21439849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12669010 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30248105 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 6744776 — Surrogate Endpoint (SUR): Blood pressure
Study 18982016 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8941105 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1610160 — Surrogate Endpoint (SUR): Blood pressure
Study 11958386 — Surrogate Endpoint (SUR): Blood pressure
Study 9622220 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30110194 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26641212 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26641212 — Surrogate Endpoint (SUR): Blood pressure
Study 17345064 — Surrogate Endpoint (SUR): Blood pressure
Study 10319784 — Surrogate Endpoint (SUR): Blood pressure
Study 24592984 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 24592984 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17300297 — Surrogate Endpoint (SUR): Blood pressure
Study 8469621 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 8469621 — Surrogate Endpoint (SUR): Blood pressure
Study 30755470 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23360122 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 18617122 — Surrogate Endpoint (SUR): Blood pressure
Study 21417807 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 21417807 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17012527 — Surrogate Endpoint (SUR): Blood pressure
Study 24080592 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24080592 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20498621 — Surrogate Endpoint (SUR): Blood pressure
Study 12836810 — Surrogate Endpoint (SUR): Blood pressure
Study 11144703 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6121181 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 30661690 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 30661690 — Surrogate Endpoint (SUR): Blood pressure
Study 21805159 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 11732835 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 8678251 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 395958 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 10412778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10412778 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10412778 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7159502 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24747412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22446022 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20664555 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 20664555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18641106 — Surrogate Endpoint (SUR): Bone mineral density
Study 10872897 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1610414 — Surrogate Endpoint (SUR): Blood pressure
Study 26866428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31445363 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31445363 — Surrogate Endpoint (SUR): Blood pressure
Study 16449264 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11774820 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8381187 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3116821 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26431718 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 11473953 — Surrogate Endpoint (SUR): Serum testosterone
Study 24660591 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 24660591 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24660591 — Surrogate Endpoint (SUR): Serum triglycerides
Study 14511896 — Surrogate Endpoint (SUR): Blood pressure
Study 9314453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9314453 — Surrogate Endpoint (SUR): Serum potassium
Study 26677862 — Surrogate Endpoint (SUR): Serum calcium
Study 26677862 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 26677862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23973155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23973155 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23973155 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23973155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23973155 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31206155 — Predictive Biomarker (PRD): OPRK1 mRNA
Genes: OPRK1; OPRK
Study 31206155 — Predictive Biomarker (PRD): OPRD1 mRNA
Genes: OPRD1; OPRD
Study 27543801 — Surrogate Endpoint (SUR): Blood pressure
Study 25398129 — Surrogate Endpoint (SUR): Serum creatinine
Study 17521052 — Surrogate Endpoint (SUR): Serum creatinine
Study 27687648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23538338 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 1588392 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31593637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27025586 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 25036199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22418829 — Surrogate Endpoint (SUR): Blood pressure
Study 6401193 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 6401193 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29211888 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19857859 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8909345 — Surrogate Endpoint (SUR): Blood pressure
Study 1327632 — Surrogate Endpoint (SUR): Blood pressure
Study 29318159 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29318159 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20493567 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 20493567 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 20493567 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 16719233 — Surrogate Endpoint (SUR): Blood pressure
Study 9688399 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 9688399 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 9688399 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9688399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25179493 — Monitoring Biomarker (MOI): HBV DNA
Study 25179493 — Surrogate Endpoint (SUR): Bone mineral density
Study 9249774 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9249774 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 17586782 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16724337 — Surrogate Endpoint (SUR): Blood pressure
Study 12599046 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1767056 — Surrogate Endpoint (SUR): Blood pressure
Study 24088126 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 4001280 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 29197219 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 23523459 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12201213 — Surrogate Endpoint (SUR): Bone mineral density
Study 12201213 — Surrogate Endpoint (SUR): Blood pressure
Study 19640950 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 12138263 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12138263 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8023779 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8023779 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11199189 — Surrogate Endpoint (SUR): Bone mineral density
Study 2935497 — Surrogate Endpoint (SUR): Blood pressure
Study 2684916 — Surrogate Endpoint (SUR): Blood pressure
Study 26573188 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 26573188 — Monitoring Biomarker (MOI): HBV DNA
Study 20586147 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16785773 — Surrogate Endpoint (SUR): Blood pressure
Study 9084355 — Surrogate Endpoint (SUR): Blood pressure
Study 1177792 — Surrogate Endpoint (SUR): Blood pressure
Study 27438754 — Surrogate Endpoint (SUR): Blood pressure
Study 15569860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15569860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15569860 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15569860 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15569860 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12101076 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12101076 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 23151354 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23151354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23151354 — Surrogate Endpoint (SUR): Blood pressure