TrialPanorama/TrialPanorama-database huggingface dataset:
Study 14588450 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 30107283 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 29943364 — Surrogate Endpoint (SUR): Serum creatinine
Study 21372694 — Surrogate Endpoint (SUR): Blood pressure
Study 17970056 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 11340346 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9701103 — Surrogate Endpoint (SUR): Blood pressure
Study 18793245 — Surrogate Endpoint (SUR): Serum calcium
Study 27577177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27577177 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 15033400 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11793859 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 11793859 — Surrogate Endpoint (SUR): Serum creatinine
Study 25917434 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 16492219 — Surrogate Endpoint (SUR): Blood pressure
Study 10880416 — Predictive Biomarker (PRD): SCARA3 mRNA
Genes: SCARA3; CSR
Study 11890650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7930736 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7930736 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 3283292 — Surrogate Endpoint (SUR): Blood pressure
Study 24326529 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 19074207 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28815689 — Surrogate Endpoint (SUR): Blood pressure
Study 27264224 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 27264224 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22948196 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21191426 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9856967 — Surrogate Endpoint (SUR): Blood pressure
Study 2744779 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20977840 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20977840 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8466735 — Surrogate Endpoint (SUR): Blood pressure
Study 31356456 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 16159869 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9585718 — Surrogate Endpoint (SUR): Blood pressure
Study 8142644 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 21697704 — Surrogate Endpoint (SUR): Blood pressure
Study 2579902 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2579902 — Surrogate Endpoint (SUR): Blood pressure
Study 31171508 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 31171508 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 19576090 — Monitoring Biomarker (MOI): Procalcitonin
Study 9578186 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10610011 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1725026 — Surrogate Endpoint (SUR): Blood pressure
Study 1725026 — Surrogate Endpoint (SUR): Serum creatinine
Study 18084949 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23949882 — Surrogate Endpoint (SUR): Serum testosterone
Study 12800099 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22038992 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20337621 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20337621 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 20337621 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20337621 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18407904 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10071426 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 12836712 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23544125 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 23544125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18194486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18194486 — Surrogate Endpoint (SUR): Blood pressure
Study 18194486 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18194486 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18194486 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14615636 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 10636509 — Surrogate Endpoint (SUR): Bone mineral density
Study 10636509 — Surrogate Endpoint (SUR): Blood pressure
Study 10636509 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30710614 — Surrogate Endpoint (SUR): Serum calcium
Study 20357251 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11260566 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 23497371 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16965776 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 16965776 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 16965776 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30287050 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 25833816 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25833816 — Surrogate Endpoint (SUR): Blood pressure
Study 23924233 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 23924233 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9542480 — Surrogate Endpoint (SUR): Blood pressure
Study 28380495 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 19901194 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20721962 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15625254 — Surrogate Endpoint (SUR): Blood pressure
Study 17072741 — Surrogate Endpoint (SUR): Bone mineral density
Study 16420253 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16420253 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27508319 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 27508319 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21685814 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11691649 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22314136 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25552403 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 25552403 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 25552403 — Predictive Biomarker (PRD): SLC47A2 mRNA
Genes: SLC47A2; MATE2
Study 17942872 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30451329 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 30451329 — Predictive Biomarker (PRD): CST5 mRNA
Genes: CST5
Study 30451329 — Predictive Biomarker (PRD): CD6 mRNA
Genes: CD6
Study 29891957 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 25190744 — Predictive Biomarker (PRD): SLC9A1 mRNA
Genes: SLC9A1; APNH1; NHE1
Study 25190744 — Predictive Biomarker (PRD): SLC16A4 mRNA
Genes: SLC16A4; MCT4; MCT5
Study 16765148 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 9014483 — Surrogate Endpoint (SUR): Blood pressure
Study 31535628 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28803380 — Surrogate Endpoint (SUR): Blood pressure
Study 16477089 — Surrogate Endpoint (SUR): Blood pressure
Study 10150534 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 23783643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16928807 — Surrogate Endpoint (SUR): Serum creatinine
Study 9440663 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3263868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27121901 — Safety Biomarker (SAF): Hyaluronic acid
Study 25013367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31138316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27176631 — Surrogate Endpoint (SUR): Blood pressure
Study 8390511 — Surrogate Endpoint (SUR): Blood pressure
Study 8390511 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3720365 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16917901 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11751712 — Surrogate Endpoint (SUR): Blood pressure
Study 29960156 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 25640020 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21199294 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10699324 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23171880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23171880 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21607987 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19489765 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9525336 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 9525336 — Surrogate Endpoint (SUR): Bone mineral density
Study 28929400 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 22958105 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 20670400 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 11029348 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11029348 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 12374449 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 9931196 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 11113068 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24447085 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20134408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20134408 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18800994 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2291870 — Surrogate Endpoint (SUR): Blood pressure
Study 28596452 — Surrogate Endpoint (SUR): Blood pressure
Study 11870117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25369277 — Surrogate Endpoint (SUR): Blood pressure
Study 21859489 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 8029191 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15321623 — Surrogate Endpoint (SUR): Blood pressure
Study 8170529 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23171639 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 10805207 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24769011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24769011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17106718 — Surrogate Endpoint (SUR): Blood pressure
Study 15741989 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12067941 — Surrogate Endpoint (SUR): Blood pressure
Study 12067941 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12067941 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12067941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2374566 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 361463 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28619061 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 28619061 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12472796 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8478661 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26526702 — Surrogate Endpoint (SUR): Blood pressure
Study 22032285 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 17971716 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21596364 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21596364 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2505269 — Predictive Biomarker (PRD): TTPA mRNA
Genes: TTPA; TPP1
Study 20199786 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20199786 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11973215 — Surrogate Endpoint (SUR): Blood pressure
Study 25239479 — Surrogate Endpoint (SUR): Blood pressure
Study 11773293 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27524498 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 15452182 — Predictive Biomarker (PRD): ZBTB7A mRNA
Genes: ZBTB7A; FBI1; LRF; ZBTB7; ZNF857A
Study 9098477 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 9098477 — Safety Biomarker (SAF): Reactive oxygen species
Study 8082875 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8082875 — Surrogate Endpoint (SUR): Blood pressure
Study 31023432 — Surrogate Endpoint (SUR): Blood pressure
Study 9870472 — Surrogate Endpoint (SUR): Blood pressure
Study 21911723 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 17900778 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 24767603 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 20339354 — Surrogate Endpoint (SUR): Blood pressure
Study 18823460 — Surrogate Endpoint (SUR): Blood pressure
Study 7595953 — Surrogate Endpoint (SUR): Blood pressure
Study 31625020 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 31625020 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27256706 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 11531952 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11531952 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12965981 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26903712 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 26903712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25062420 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25062420 — Surrogate Endpoint (SUR): Blood pressure
Study 25062420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17574819 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17574819 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25672274 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 17168431 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 8889855 — Surrogate Endpoint (SUR): Bone mineral density
Study 20236990 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31843638 — Surrogate Endpoint (SUR): Blood pressure
Study 29727043 — Surrogate Endpoint (SUR): Serum asparaginase
Study 24928586 — Surrogate Endpoint (SUR): Blood pressure
Study 24928586 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7789631 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7789631 — Surrogate Endpoint (SUR): Blood pressure
Study 17470864 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17470864 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17470864 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23601264 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 3341391 — Surrogate Endpoint (SUR): Blood pressure
Study 3341391 — Surrogate Endpoint (SUR): Serum sodium
Study 3341391 — Surrogate Endpoint (SUR): Serum potassium
Study 3341391 — Surrogate Endpoint (SUR): Serum uric acid
Study 31424957 — Predictive Biomarker (PRD): SOX2 mRNA
Genes: SOX2
Study 26814847 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 23754758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21472664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21472664 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9080918 — Surrogate Endpoint (SUR): Blood pressure
Study 30485450 — Predictive Biomarker (PRD): CEMIP mRNA
Genes: CEMIP; KIAA1199
Study 12912807 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 12912807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24755206 — Surrogate Endpoint (SUR): Blood pressure
Study 15353973 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15353973 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 15353973 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9870830 — Surrogate Endpoint (SUR): Serum creatinine
Study 27940188 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 23818981 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19436136 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 19436136 — Predictive Biomarker (PRD): GGCX mRNA
Genes: GGCX; GC
Study 12844212 — Surrogate Endpoint (SUR): Bone mineral density
Study 10993791 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8996468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31034598 — Predictive Biomarker (PRD): CD248 mRNA
Genes: CD248; CD164L1; TEM1
Study 23375525 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 23375525 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23375525 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23375525 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23375525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23375525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23375525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21410828 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9824345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2532184 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 26297701 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26297701 — Safety Biomarker (SAF): BDNF
Study 31260526 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23810874 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23810874 — Surrogate Endpoint (SUR): Blood pressure
Study 28606620 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 25809853 — Surrogate Endpoint (SUR): Blood pressure
Study 25809853 — Surrogate Endpoint (SUR): Plasma sitosterol and campesterol
Study 25809853 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10631214 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16086559 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 7827843 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26678630 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21550084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21550084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6381166 — Surrogate Endpoint (SUR): Blood pressure
Study 27081016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12351377 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 12351377 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 24089227 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8205303 — Surrogate Endpoint (SUR): Blood pressure
Study 31228031 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 10993032 — Surrogate Endpoint (SUR): Bone mineral density
Study 24709487 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24709487 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 12745799 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8340983 — Surrogate Endpoint (SUR): Bone mineral density
Study 12556405 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12556405 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 956557 — Surrogate Endpoint (SUR): Blood pressure
Study 21647703 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21647703 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11140385 — Predictive Biomarker (PRD): HPGDS mRNA
Genes: HPGDS; GSTS; PGDS; PTGDS2
Study 7950179 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28811158 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 21128879 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 21128879 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol