TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16837133 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 12771740 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 6734028 — Surrogate Endpoint (SUR): Blood pressure
Study 22900989 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22900989 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22900989 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19858319 — Surrogate Endpoint (SUR): Bone mineral density
Study 31429418 — Surrogate Endpoint (SUR): Blood pressure
Study 12036673 — Surrogate Endpoint (SUR): Blood pressure
Study 7130643 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31627723 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 26590130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19843057 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 15848604 — Surrogate Endpoint (SUR): Serum creatinine
Study 2311588 — Surrogate Endpoint (SUR): Blood pressure
Study 25041550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9860152 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9860152 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 7630145 — Surrogate Endpoint (SUR): Blood pressure
Study 31079282 — Predictive Biomarker (PRD): Hormone receptor
Study 21357809 — Surrogate Endpoint (SUR): Bone mineral density
Study 7835781 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7835781 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 19628570 — Predictive Biomarker (PRD): Hormone receptor
Study 23826157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23826157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24351694 — Surrogate Endpoint (SUR): Blood pressure
Study 26432508 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25369006 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25369006 — Surrogate Endpoint (SUR): Blood pressure
Study 15972934 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15972934 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14677527 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1439067 — Surrogate Endpoint (SUR): Blood pressure
Study 1439067 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15824372 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 10402766 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10402766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8404107 — Surrogate Endpoint (SUR): Blood pressure
Study 3777548 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 20353120 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 18718815 — Surrogate Endpoint (SUR): Bone mineral density
Study 12860219 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8622227 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9620109 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21425144 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15557515 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7513776 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31807987 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 23909286 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21752462 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 26856320 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26856320 — Surrogate Endpoint (SUR): Blood pressure
Study 23683727 — Surrogate Endpoint (SUR): Bone mineral density
Study 23107780 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31081371 — Surrogate Endpoint (SUR): Blood pressure
Study 21836134 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21836134 — Surrogate Endpoint (SUR): Blood pressure
Study 12871363 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12871363 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10865409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10865409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10865409 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1359619 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26831677 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 22721966 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19670096 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 15141795 — Surrogate Endpoint (SUR): Blood pressure
Study 2778791 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2778791 — Surrogate Endpoint (SUR): Blood pressure
Study 19749494 — Surrogate Endpoint (SUR): Blood pressure
Study 19749494 — Surrogate Endpoint (SUR): Serum creatinine
Study 9156046 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25142085 — Surrogate Endpoint (SUR): Serum creatinine
Study 20664198 — Surrogate Endpoint (SUR): Serum creatinine
Study 1706244 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6594926 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15522049 — Surrogate Endpoint (SUR): Blood pressure
Study 11990165 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18982860 — Surrogate Endpoint (SUR): Serum sodium
Study 8077767 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8077767 — Safety Biomarker (SAF): Interleukin 1
Study 25989827 — Safety Biomarker (SAF): Reactive oxygen species
Study 25989827 — Surrogate Endpoint (SUR): Serum creatinine
Study 23799707 — Surrogate Endpoint (SUR): Blood pressure
Study 21723606 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16490616 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16490616 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1345803 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30120403 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24083783 — Surrogate Endpoint (SUR): Blood pressure
Study 21906708 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 16005229 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16005229 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16005229 — Predictive Biomarker (PRD): Hormone receptor
Study 6130295 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25847819 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 21304215 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16681770 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 16681770 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 16681770 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 16681770 — Predictive Biomarker (PRD): HRAS mRNA
Genes: HRAS; HRAS1
Study 16681770 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 16681770 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 16681770 — Predictive Biomarker (PRD): CTSB mRNA
Genes: CTSB; CPSB
Study 16681770 — Predictive Biomarker (PRD): RPS6KB1 mRNA
Genes: RPS6KB1; STK14A
Study 16681770 — Predictive Biomarker (PRD): LAMC2 mRNA
Genes: LAMC2; LAMB2T; LAMNB2
Study 16681770 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 16681770 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 14975458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 10345907 — Surrogate Endpoint (SUR): Blood pressure
Study 30737835 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21705068 — Surrogate Endpoint (SUR): Blood pressure
Study 2949974 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 24943673 — Surrogate Endpoint (SUR): Blood pressure
Study 8842608 — Surrogate Endpoint (SUR): Blood pressure
Study 29478929 — Surrogate Endpoint (SUR): Probing pocket depth
Study 14583235 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 14583235 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10890617 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 7602235 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 19955857 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 3392240 — Surrogate Endpoint (SUR): Blood pressure
Study 12553951 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 10714908 — Surrogate Endpoint (SUR): Blood pressure
Study 9215540 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 26720025 — Predictive Biomarker (PRD): Hormone receptor
Study 26025097 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24750838 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 30672175 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21189915 — Surrogate Endpoint (SUR): Blood pressure
Study 15622265 — Safety Biomarker (SAF): Hyaluronic acid
Study 2147405 — Surrogate Endpoint (SUR): Blood pressure
Study 17961204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17961204 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17961204 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17961204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9466468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9466468 — Safety Biomarker (SAF): IL-6 and IL-10
Study 28824047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18433528 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16487219 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16487219 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9686072 — Surrogate Endpoint (SUR): Blood pressure
Study 26465374 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26465374 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 21391876 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18498540 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 11335776 — Surrogate Endpoint (SUR): Serum hemoglobin A1C
Study 9383177 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31562608 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26010524 — Surrogate Endpoint (SUR): Blood pressure
Study 16098233 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 26502012 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26066644 — Surrogate Endpoint (SUR): Blood pressure
Study 17882235 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 1595920 — Surrogate Endpoint (SUR): Blood pressure
Study 24870737 — Surrogate Endpoint (SUR): Blood pressure
Study 24071915 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 9879725 — Predictive Biomarker (PRD): MZB1 mRNA
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 31351869 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 31351869 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31351869 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 11029607 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 11029607 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2828289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 2828289 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 23036096 — Predictive Biomarker (PRD): NRF1 mRNA
Genes: NRF1
Study 23036096 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 21740798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11710708 — Safety Biomarker (SAF): MTHFR
Study 9385480 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9385480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31342604 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 22569992 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 22569992 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 22569992 — Predictive Biomarker (PRD): RRM2 mRNA
Genes: RRM2; RR2
Study 22569992 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 10798765 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 22735431 — Surrogate Endpoint (SUR): Blood pressure
Study 17366357 — Surrogate Endpoint (SUR): Blood pressure
Study 28032333 — Surrogate Endpoint (SUR): Blood pressure
Study 14601471 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14601471 — Surrogate Endpoint (SUR): Blood pressure
Study 15461606 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 2195579 — Surrogate Endpoint (SUR): Blood pressure
Study 31418022 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29351542 — Safety Biomarker (SAF): Hyaluronic acid
Study 16708735 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11689582 — Predictive Biomarker (PRD): Hormone receptor
Study 25688159 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25688159 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25688159 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24308874 — Surrogate Endpoint (SUR): Blood pressure
Study 10499748 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10499748 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 10499748 — Surrogate Endpoint (SUR): Blood pressure
Study 27578574 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 27578574 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 31444669 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17886213 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11795349 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11795349 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11795349 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11795349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18536698 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 10759443 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 30939537 — Surrogate Endpoint (SUR): Bone mineral density
Study 24534225 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 16900557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11824858 — Surrogate Endpoint (SUR): Blood pressure
Study 31187186 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 23676183 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 23676183 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10867972 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 8778949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8778949 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 27315134 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 19853399 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10446037 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7796786 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30430745 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 24621834 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17591024 — Monitoring Biomarker (MOI): HBV DNA
Study 28342988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28342988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28342988 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 21749214 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 18246327 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16524854 — Surrogate Endpoint (SUR): Blood pressure
Study 24739073 — Surrogate Endpoint (SUR): Blood pressure
Study 7936332 — Surrogate Endpoint (SUR): Blood pressure
Study 2678584 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31519285 — Surrogate Endpoint (SUR): Blood pressure
Study 31519285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31519285 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20601207 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18049436 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 18049436 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16215365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30951521 — Surrogate Endpoint (SUR): Total kidney volume
Study 30951521 — Surrogate Endpoint (SUR): Serum creatinine
Study 15759021 — Surrogate Endpoint (SUR): Blood pressure
Study 25605660 — Surrogate Endpoint (SUR): Blood pressure
Study 25605660 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23413981 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 17237444 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 17237444 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17237444 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 17237444 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 17237444 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 17237444 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10740160 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19819677 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19819677 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11751734 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30587918 — Surrogate Endpoint (SUR): Blood pressure
Study 20507967 — Predictive Biomarker (PRD): ACTN3 mRNA
Genes: ACTN3
Study 20507967 — Predictive Biomarker (PRD): CSRP3 mRNA
Genes: CSRP3; CLP; MLP
Study 20507967 — Predictive Biomarker (PRD): RCAN1 mRNA
Genes: RCAN1; ADAPT78; CSP1; DSC1; DSCR1
Study 17640422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17640422 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 17640422 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17640422 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 17640422 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 17640422 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15920053 — Surrogate Endpoint (SUR): Blood pressure
Study 10366795 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 6241622 — Surrogate Endpoint (SUR): Blood pressure
Study 26865601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17316115 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 30860588 — Surrogate Endpoint (SUR): Blood pressure
Study 25224595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23834543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23834543 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 18250271 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10834689 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30568303 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30568303 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 30568303 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27097076 — Surrogate Endpoint (SUR): Blood pressure
Study 27097076 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12503709 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9622312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 196167 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30145946 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18996225 — Surrogate Endpoint (SUR): Serum testosterone
Study 15302778 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 28550240 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 28550240 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 28550240 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16570038 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD