TrialPanorama/TrialPanorama-database huggingface dataset:
Study 6666222 — Surrogate Endpoint (SUR): Blood pressure
Study 30231074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28110894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28110894 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 9070551 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12959317 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 3772833 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 31758920 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31758920 — Predictive Biomarker (PRD): SULT1A1 mRNA
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 23770788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23770788 — Safety Biomarker (SAF): Reactive oxygen species
Study 23770788 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18485028 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 14553956 — Surrogate Endpoint (SUR): Blood pressure
Study 11061364 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2439798 — Surrogate Endpoint (SUR): Blood pressure
Study 31306389 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31306389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31306389 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31306389 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24313546 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24313546 — Surrogate Endpoint (SUR): Blood pressure
Study 24313546 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12022620 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 24916555 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18415809 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 25790673 — Predictive Biomarker (PRD): DOCK3 mRNA
Genes: DOCK3; KIAA0299; MOCA
Study 23521816 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23521816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15063428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20503397 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12645716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10389911 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10389911 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31594635 — Predictive Biomarker (PRD): Hormone receptor
Study 26754625 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 26754625 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17536453 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9542322 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 9542322 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24266960 — Surrogate Endpoint (SUR): Blood pressure
Study 24266960 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17194902 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 8143399 — Surrogate Endpoint (SUR): Blood pressure
Study 28526381 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23731242 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19885781 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 19885781 — Surrogate Endpoint (SUR): Serum testosterone
Study 16456024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16456024 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 16456024 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 23764734 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 17641003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12532161 — Surrogate Endpoint (SUR): Blood pressure
Study 17434899 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12927020 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12927020 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9174500 — Surrogate Endpoint (SUR): Blood pressure
Study 20807460 — Surrogate Endpoint (SUR): Blood pressure
Study 18537939 — Predictive Biomarker (PRD): OPRD1 mRNA
Genes: OPRD1; OPRD
Study 18537939 — Predictive Biomarker (PRD): OPRK1 mRNA
Genes: OPRK1; OPRK
Study 17010738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7047173 — Surrogate Endpoint (SUR): Blood pressure
Study 27454528 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18710605 — Surrogate Endpoint (SUR): Blood pressure
Study 17617307 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 17617307 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 14983420 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 11607801 — Surrogate Endpoint (SUR): Blood pressure
Study 9699761 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26273138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23732551 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19643572 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 7798822 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29621201 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 29621201 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 29621201 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29621201 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 29621201 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29621201 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 18029476 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18029476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18029476 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 7607280 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26160210 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26160210 — Surrogate Endpoint (SUR): Blood pressure
Study 22997212 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16554455 — Surrogate Endpoint (SUR): Urine free cortisol
Study 12713767 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3969861 — Surrogate Endpoint (SUR): Blood pressure
Study 20973735 — Surrogate Endpoint (SUR): Serum hemoglobin A1C
Study 20973735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20973735 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11145325 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 21164548 — Surrogate Endpoint (SUR): Blood pressure
Study 21164548 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21164548 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3896555 — Surrogate Endpoint (SUR): Serum creatinine
Study 22215656 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22215656 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22215656 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28158151 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 18467721 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 27973684 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 27973684 — Safety Biomarker (SAF): Hyaluronic acid
Study 26359007 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23829159 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19074546 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 8190572 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 30051222 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 22853847 — Surrogate Endpoint (SUR): Blood pressure
Study 20929124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18761785 — Surrogate Endpoint (SUR): Blood pressure
Study 17906162 — Surrogate Endpoint (SUR): Serum potassium
Study 17906162 — Surrogate Endpoint (SUR): Blood pressure
Study 30585458 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17628686 — Surrogate Endpoint (SUR): Blood pressure
Study 26549704 — Surrogate Endpoint (SUR): Serum testosterone
Study 15159685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9792567 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 834152 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31354089 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 17516972 — Surrogate Endpoint (SUR): Blood pressure
Study 26302093 — Surrogate Endpoint (SUR): Blood pressure
Study 21318601 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17389292 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17389292 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15009002 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 3102991 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26511012 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24374901 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24374901 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24374901 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 22745145 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 22745145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22745145 — Monitoring Biomarker (MOI): Procalcitonin
Study 17427172 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 15583702 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 7843752 — Surrogate Endpoint (SUR): Blood pressure
Study 7843752 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2192572 — Surrogate Endpoint (SUR): Blood pressure
Study 30792343 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 17542407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14718904 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 8516521 — Surrogate Endpoint (SUR): Blood pressure
Study 26158245 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19827055 — Surrogate Endpoint (SUR): Blood pressure
Study 20184589 — Surrogate Endpoint (SUR): Blood pressure
Study 25425220 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 17608679 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8168806 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 3285215 — Surrogate Endpoint (SUR): Serum creatinine
Study 19401349 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14751655 — Surrogate Endpoint (SUR): Blood pressure
Study 30843141 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29176462 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 23313603 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 22137068 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19005996 — Surrogate Endpoint (SUR): Serum calcium
Study 19005996 — Surrogate Endpoint (SUR): Serum creatinine
Study 31832789 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7965483 — Surrogate Endpoint (SUR): Serum sodium
Study 30355202 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24645944 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22210563 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 20153269 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12970211 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30341114 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 12426644 — Surrogate Endpoint (SUR): Blood pressure
Study 2028533 — Surrogate Endpoint (SUR): Blood pressure
Study 28727540 — Surrogate Endpoint (SUR): Blood pressure
Study 15130569 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 7974337 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26866103 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15015439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23328596 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 1685362 — Surrogate Endpoint (SUR): Blood pressure
Study 6158478 — Surrogate Endpoint (SUR): Blood pressure
Study 10682457 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9012296 — Surrogate Endpoint (SUR): Blood pressure
Study 30462199 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 30462199 — Surrogate Endpoint (SUR): Blood pressure
Study 30843421 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 28193574 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 28193574 — Surrogate Endpoint (SUR): Blood pressure
Study 21950196 — Predictive Biomarker (PRD): RAB8A mRNA
Genes: RAB8A; MEL; RAB8
Study 24939677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23126252 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 23126252 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23126252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23126252 — Surrogate Endpoint (SUR): Blood pressure
Study 20483049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20483049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20483049 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20483049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15768049 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 15768049 — Safety Biomarker (SAF): BDNF
Study 1710673 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31403867 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31403867 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 31403867 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19918967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19918967 — Safety Biomarker (SAF): Interleukin 12
Study 12824968 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 1725004 — Surrogate Endpoint (SUR): Blood pressure
Study 6151789 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 23007025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19064125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9816086 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8985525 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 31423712 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31423712 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27335279 — Surrogate Endpoint (SUR): Blood pressure
Study 27335279 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15182776 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11252212 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9416938 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11443185 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 11443185 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25258407 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 18793544 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30706457 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23427748 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 10805203 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1479709 — Surrogate Endpoint (SUR): Serum creatinine
Study 1479709 — Surrogate Endpoint (SUR): Blood pressure
Study 15716707 — Surrogate Endpoint (SUR): Blood pressure
Study 2525897 — Surrogate Endpoint (SUR): Blood pressure
Study 24986094 — Surrogate Endpoint (SUR): Blood pressure
Study 15455743 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 15455743 — Predictive Biomarker (PRD): TKT mRNA
Genes: TKT
Study 19047288 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 16884320 — Surrogate Endpoint (SUR): Serum uric acid
Study 10564141 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 27108818 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18515672 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10357241 — Surrogate Endpoint (SUR): Blood pressure
Study 26058585 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21228269 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 21228269 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16580384 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10666351 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9586788 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29843761 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 26232375 — Surrogate Endpoint (SUR): Bone mineral density
Study 19660605 — Surrogate Endpoint (SUR): Serum creatinine
Study 19660605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19660605 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9059867 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23112824 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23112824 — Surrogate Endpoint (SUR): Blood pressure
Study 23112824 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23112824 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2161614 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27979988 — Surrogate Endpoint (SUR): Blood pressure
Study 21134328 — Surrogate Endpoint (SUR): Blood pressure
Study 12045491 — Predictive Biomarker (PRD): SRY mRNA
Genes: SRY; TDF
Study 22306193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20544348 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18371094 — Predictive Biomarker (PRD): SLA mRNA
Genes: SLA; SLAP; SLAP1
Study 26450680 — Surrogate Endpoint (SUR): Serum calcium
Study 26450680 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 26450680 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 3279969 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31232638 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 3034040 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3034040 — Surrogate Endpoint (SUR): Blood pressure
Study 21908683 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 26559317 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24285938 — Surrogate Endpoint (SUR): Blood pressure
Study 30412281 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30605935 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 24495042 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20179212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20179212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17296972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17296972 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17296972 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 25220555 — Surrogate Endpoint (SUR): Blood pressure
Study 15255284 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8315574 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8315574 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4