TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19769631 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 18729836 — Surrogate Endpoint (SUR): Blood pressure
Study 15922556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31756535 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 31756535 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 31756535 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 31756535 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 24171680 — Surrogate Endpoint (SUR): Bone mineral density
Study 1320920 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27517680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27517680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27517680 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 25784665 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study 6378354 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23378247 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 20604675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 20604675 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20604675 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23298339 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23298339 — Surrogate Endpoint (SUR): Bone mineral density
Study 25664394 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25664394 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25664394 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 21866183 — Surrogate Endpoint (SUR): Blood pressure
Study 16960440 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16314870 — Predictive Biomarker (PRD): PICK1 mRNA
Genes: PICK1; PRKCABP
Study 10867093 — Surrogate Endpoint (SUR): Blood pressure
Study 8471652 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 8471652 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 21349603 — Surrogate Endpoint (SUR): Blood pressure
Study 11674909 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 2962799 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17581158 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8156047 — Surrogate Endpoint (SUR): Blood pressure
Study 23278590 — Surrogate Endpoint (SUR): Platelet count response
Study 17154377 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7959860 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 8686198 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8686198 — Surrogate Endpoint (SUR): Blood pressure
Study 24534219 — Predictive Biomarker (PRD): FDPS mRNA
Genes: FDPS; FPS; KIAA1293
Study 24534219 — Surrogate Endpoint (SUR): Bone mineral density
Study 10361239 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10361239 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10361239 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 10361239 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 10361239 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10361239 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20667004 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10451784 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18601850 — Surrogate Endpoint (SUR): Blood pressure
Study 7800212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21810018 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21810018 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27555187 — Surrogate Endpoint (SUR): Blood pressure
Study 24722560 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24722560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16365195 — Surrogate Endpoint (SUR): Blood pressure
Study 11484954 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8112187 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8112187 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8112187 — Surrogate Endpoint (SUR): Blood pressure
Study 8112187 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3381757 — Surrogate Endpoint (SUR): Blood pressure
Study 30689476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30689476 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 30689476 — Safety Biomarker (SAF): Reactive oxygen species
Study 21518677 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 21518677 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 11700398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3499182 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27900818 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 23522788 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23522788 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 11157326 — Surrogate Endpoint (SUR): Serum calcium
Study 9622114 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30502505 — Surrogate Endpoint (SUR): Platelet count response
Study 19562716 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26048096 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26048096 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26048096 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 24884753 — Surrogate Endpoint (SUR): Blood pressure
Study 2110937 — Surrogate Endpoint (SUR): Serum triglycerides
Study 373940 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22616580 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16207152 — Surrogate Endpoint (SUR): Blood pressure
Study 22092915 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 22092915 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 20231786 — Surrogate Endpoint (SUR): Bone mineral density
Study 8424733 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28800398 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28800398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11565320 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11565320 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11565320 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9627524 — Surrogate Endpoint (SUR): Blood pressure
Study 7933821 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29048352 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29048352 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 29048352 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 19080741 — Predictive Biomarker (PRD): Hormone receptor
Study 9399371 — Surrogate Endpoint (SUR): Blood pressure
Study 27422625 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27422625 — Surrogate Endpoint (SUR): Blood pressure
Study 25409020 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20534062 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2505698 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2505698 — Surrogate Endpoint (SUR): Serum creatinine
Study 31969369 — Surrogate Endpoint (SUR): Blood pressure
Study 22510791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22510791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18525382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6712861 — Surrogate Endpoint (SUR): Blood pressure
Study 31309919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22580729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22580729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19101220 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 2156887 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31895769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31895769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31722623 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 20082930 — Surrogate Endpoint (SUR): Blood pressure
Study 20082930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20082930 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8192130 — Surrogate Endpoint (SUR): Blood pressure
Study 26680374 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 19225466 — Surrogate Endpoint (SUR): Serum testosterone
Study 11956118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1968739 — Surrogate Endpoint (SUR): Blood pressure
Study 655186 — Surrogate Endpoint (SUR): Blood pressure
Study 30801994 — Surrogate Endpoint (SUR): Serum creatinine
Study 27789350 — Surrogate Endpoint (SUR): Bone mineral density
Study 23632801 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 9760817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8310978 — Surrogate Endpoint (SUR): Blood pressure
Study 3131884 — Surrogate Endpoint (SUR): Blood pressure
Study 24432037 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24432037 — Surrogate Endpoint (SUR): Blood pressure
Study 12688320 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 21695708 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16954654 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31292301 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25210879 — Surrogate Endpoint (SUR): Blood pressure
Study 7572707 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6434081 — Surrogate Endpoint (SUR): Serum calcium
Study 6434081 — Surrogate Endpoint (SUR): Serum creatinine
Study 24872684 — Surrogate Endpoint (SUR): Blood pressure
Study 30738649 — Surrogate Endpoint (SUR): Blood pressure
Study 29137465 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8587457 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19687345 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16032375 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16032375 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 16032375 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16032375 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16032375 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2419687 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24002013 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23227581 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20171939 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 20171939 — Surrogate Endpoint (SUR): Blood pressure
Study 15992513 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 15992513 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9583287 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25412669 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 25412669 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 1912407 — Surrogate Endpoint (SUR): Serum creatinine
Study 18040527 — Safety Biomarker (SAF): Reactive oxygen species
Study 9352981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28835513 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28835513 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 28835513 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 24092379 — Predictive Biomarker (PRD): ANKS4B mRNA
Genes: ANKS4B; HARP
Study 22682082 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 18176233 — Safety Biomarker (SAF): Hyaluronic acid
Study 1353607 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31587102 — Safety Biomarker (SAF): Hypoxanthine-guanine phosphoribosyltransferase
Genes: HPRT1; HPRT
Study 20210592 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 8720766 — Surrogate Endpoint (SUR): Blood pressure
Study 2809856 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28817535 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22986420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17050227 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11082781 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 29696666 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 15880333 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11908598 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2615928 — Surrogate Endpoint (SUR): Blood pressure
Study 9636831 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9636831 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27898071 — Surrogate Endpoint (SUR): Blood pressure
Study 22510538 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 9194508 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 9194508 — Surrogate Endpoint (SUR): Blood pressure
Study 2457711 — Predictive Biomarker (PRD): PLAT mRNA
Genes: PLAT
Study 2457711 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2457711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7911820 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 7911820 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7911820 — Surrogate Endpoint (SUR): Serum creatinine
Study 31637971 — Surrogate Endpoint (SUR): Blood pressure
Study 26472518 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 22906039 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 29457540 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25274192 — Surrogate Endpoint (SUR): Serum calcium
Study 29275370 — Surrogate Endpoint (SUR): Blood pressure
Study 17905097 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 17911482 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17911482 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17911482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28232854 — Surrogate Endpoint (SUR): Blood pressure
Study 27834418 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 27834418 — Surrogate Endpoint (SUR): Bone mineral density
Study 27834418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15918444 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 15918444 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15918444 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7593897 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 27554534 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15040822 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 12899358 — Surrogate Endpoint (SUR): Blood pressure
Study 29582248 — Predictive Biomarker (PRD): GPR119 mRNA
Genes: GPR119
Study 22415421 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 22415421 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 20306184 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20306184 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24664788 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 24664788 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 15894675 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 15894675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 15894675 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15894675 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 29203290 — Predictive Biomarker (PRD): ZBTB7A mRNA
Genes: ZBTB7A; FBI1; LRF; ZBTB7; ZNF857A
Study 26011549 — Surrogate Endpoint (SUR): Blood pressure
Study 26011549 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16614887 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 26400431 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26400431 — Surrogate Endpoint (SUR): Blood pressure
Study 12414849 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15377853 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2828406 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 3595691 — Surrogate Endpoint (SUR): Serum creatinine
Study 26331711 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21738668 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12770651 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 12770651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12770651 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 12770651 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10894377 — Surrogate Endpoint (SUR): Bone mineral density
Study 29193548 — Surrogate Endpoint (SUR): Blood pressure
Study 21969577 — Predictive Biomarker (PRD): MACROH2A1 mRNA
Genes: MACROH2A1; H2AFY
Study 18359746 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 12641642 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 31872552 — Surrogate Endpoint (SUR): Sperm parameters
Study 30182858 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 7944693 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3410630 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 3410630 — Surrogate Endpoint (SUR): Serum testosterone
Study 12748343 — Surrogate Endpoint (SUR): Blood pressure
Study 8796234 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2142949 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2142949 — Surrogate Endpoint (SUR): Serum creatinine
Study 301743 — Surrogate Endpoint (SUR): Blood pressure
Study 28371189 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21426749 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9635475 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 1448121 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31856618 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 28283018 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25723884 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15455740 — Safety Biomarker (SAF): Hyaluronic acid
Study 31173645 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 23816526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1550080 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26107256 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 20568437 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20568437 — Surrogate Endpoint (SUR): Blood pressure
Study 18806616 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10576173 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8244130 — Surrogate Endpoint (SUR): Blood pressure
Study 18701766 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 15714213 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell