TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1487551 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1487551 — Surrogate Endpoint (SUR): Blood pressure
Study 28315450 — Safety Biomarker (SAF): Reactive oxygen species
Study 25824243 — Predictive Biomarker (PRD): FAH mRNA
Genes: FAH
Study 17251237 — Surrogate Endpoint (SUR): Blood pressure
Study 15027793 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23925369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23925369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23925369 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21125336 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17123215 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 8394796 — Surrogate Endpoint (SUR): Blood pressure
Study 8394796 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3205554 — Surrogate Endpoint (SUR): Blood pressure
Study 31158553 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 25645191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23895706 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23895706 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 19644434 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 19644434 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 11559718 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11559718 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26477840 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 8873687 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8873687 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 1382159 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1382159 — Surrogate Endpoint (SUR): Blood pressure
Study 31868905 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29740026 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26984449 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26984449 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 26984449 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 20223367 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11384079 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 11384079 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 11384079 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9232343 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 23861303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23861303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21653575 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 29948176 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 24661040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23717119 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 17918277 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17259791 — Surrogate Endpoint (SUR): Blood pressure
Study 17259791 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9252932 — Surrogate Endpoint (SUR): Bone mineral density
Study 3307549 — Predictive Biomarker (PRD): PLXNB1 mRNA
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 6431211 — Surrogate Endpoint (SUR): Blood pressure
Study 23207335 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 31519550 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31519550 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31519550 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 7755941 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 7755941 — Surrogate Endpoint (SUR): Blood pressure
Study 21723554 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 21723554 — Surrogate Endpoint (SUR): Blood pressure
Study 18986246 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26530543 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 21195291 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9252710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9252710 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2531608 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17159824 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 9383183 — Surrogate Endpoint (SUR): Blood pressure
Study 29397354 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 29397354 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 12420826 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8787036 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 1659934 — Surrogate Endpoint (SUR): Blood pressure
Study 29652544 — Surrogate Endpoint (SUR): Blood pressure
Study 28577670 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 26031292 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 26031292 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29615003 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20815080 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19128246 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 16787141 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 8781854 — Safety Biomarker (SAF): Reactive oxygen species
Study 3883732 — Surrogate Endpoint (SUR): Blood pressure
Study 20150290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18560257 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 18560257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25529904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25529904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21412057 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21412057 — Surrogate Endpoint (SUR): Serum creatinine
Study 19469829 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 16602327 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16602327 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10432474 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 2404502 — Surrogate Endpoint (SUR): Blood pressure
Study 30379826 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 30379826 — Surrogate Endpoint (SUR): Serum calcium
Study 30379826 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27627194 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22968888 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20335355 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10361111 — Predictive Biomarker (PRD): KDM5D mRNA
Genes: KDM5D; HY; HYA; JARID1D; KIAA0234; SMCY
Study 7595711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25225715 — Surrogate Endpoint (SUR): Blood pressure
Study 23510493 — Surrogate Endpoint (SUR): Blood pressure
Study 16861943 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 16861943 — Safety Biomarker (SAF): 51Cr-EDTA
Study 29426348 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 20233196 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 20233196 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25192259 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25192259 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20919666 — Predictive Biomarker (PRD): BCAR1 mRNA
Genes: BCAR1; CAS; CASS1; CRKAS
Study 20919666 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 19954476 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 19954476 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 9205819 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31308209 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 31308209 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19294387 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17709456 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15563362 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25016780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25016780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25016780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20002646 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 17353513 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 17353513 — Surrogate Endpoint (SUR): Blood pressure
Study 14729863 — Predictive Biomarker (PRD): APOA5 mRNA
Genes: APOA5; RAP3; UNQ411/PRO773
Study 14729863 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2198911 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 2198911 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2198911 — Surrogate Endpoint (SUR): Blood pressure
Study 219509 — Surrogate Endpoint (SUR): Blood pressure
Study 26541570 — Surrogate Endpoint (SUR): Blood pressure
Study 24568963 — Surrogate Endpoint (SUR): Serum creatinine
Study 15888205 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29417371 — Surrogate Endpoint (SUR): Blood pressure
Study 22576327 — Safety Biomarker (SAF): Hyaluronic acid
Study 1716558 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 10547079 — Surrogate Endpoint (SUR): Blood pressure
Study 1855357 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1855357 — Surrogate Endpoint (SUR): Blood pressure
Study 1389945 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24169821 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 24169821 — Surrogate Endpoint (SUR): Serum creatinine
Study 30070742 — Surrogate Endpoint (SUR): Blood pressure
Study 19212269 — Surrogate Endpoint (SUR): Blood pressure
Study 19212269 — Surrogate Endpoint (SUR): Serum creatinine
Study 19212269 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23720354 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 20644123 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 16863695 — Predictive Biomarker (PRD): KCNK3 mRNA
Genes: KCNK3; TASK; TASK1
Study 23839254 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22300693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22300693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2483580 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 27861991 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 27861991 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25651476 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 24335445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22659487 — Safety Biomarker (SAF): Reactive oxygen species
Study 20226558 — Surrogate Endpoint (SUR): Blood pressure
Study 15772571 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15772571 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2148148 — Surrogate Endpoint (SUR): Blood pressure
Study 19751435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17355820 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 7840912 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27549242 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 24244725 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 10486668 — Surrogate Endpoint (SUR): Blood pressure
Study 12621364 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 10781119 — Surrogate Endpoint (SUR): Blood pressure
Study 27002448 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 24521561 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22901350 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8282360 — Surrogate Endpoint (SUR): Blood pressure
Study 29628483 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29628483 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27886619 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22766394 — Surrogate Endpoint (SUR): Blood pressure
Study 18331816 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 9174486 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21169815 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21169815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11320559 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9134651 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2889501 — Predictive Biomarker (PRD): ASPRV1 mRNA
Genes: ASPRV1; SASP
Study 17559758 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 26825650 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22796513 — Predictive Biomarker (PRD): TKTL1 mRNA
Genes: TKTL1; TKR; TKT2
Study 15886663 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 6628792 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30384885 — Surrogate Endpoint (SUR): Blood pressure
Study 30384885 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27044332 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27044332 — Surrogate Endpoint (SUR): Blood pressure
Study 26111150 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 26111150 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 26111150 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23130583 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19040615 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 19040615 — Safety Biomarker (SAF): Human leucocyte antigen
Study 19040615 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 10561144 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 10561144 — Surrogate Endpoint (SUR): Serum calcium
Study 8991468 — Surrogate Endpoint (SUR): Blood pressure
Study 30623907 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28947757 — Surrogate Endpoint (SUR): Probing pocket depth
Study 14551368 — Surrogate Endpoint (SUR): Blood pressure
Study 10841169 — Surrogate Endpoint (SUR): Bone mineral density
Study 1301246 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1301246 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24170749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 11783269 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 384920 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21735693 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21735693 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20104753 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25440796 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25440796 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25440796 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22753208 — Surrogate Endpoint (SUR): Blood pressure
Study 15964445 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 1283586 — Surrogate Endpoint (SUR): Blood pressure
Study 6133987 — Surrogate Endpoint (SUR): Blood pressure
Study 26254237 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 24870115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11486156 — Surrogate Endpoint (SUR): Blood pressure
Study 26828801 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 18040672 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 7598139 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 870547 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 28259608 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 26553894 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 16539560 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 12649401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12649401 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8055999 — Surrogate Endpoint (SUR): Blood pressure
Study 31885802 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17598007 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 2866965 — Surrogate Endpoint (SUR): Blood pressure
Study 29412077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29412077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17487767 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 30894455 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23383171 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17085674 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 15101466 — Surrogate Endpoint (SUR): Serum creatinine
Study 9310536 — Surrogate Endpoint (SUR): Blood pressure
Study 3540212 — Monitoring Biomarker (MOI): HBV DNA
Study 19846273 — Surrogate Endpoint (SUR): Blood pressure
Study 15666120 — Surrogate Endpoint (SUR): Bone mineral density
Study 10526278 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6295132 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6295132 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31442303 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 31442303 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 29354177 — Predictive Biomarker (PRD): SULT1E1 mRNA
Genes: SULT1E1; STE
Study 29354177 — Surrogate Endpoint (SUR): Blood pressure
Study 19505878 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8922801 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27271264 — Surrogate Endpoint (SUR): Blood pressure
Study 27271264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22360645 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 22360645 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 18707986 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18707986 — Surrogate Endpoint (SUR): Serum creatinine
Study 9404698 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 9404698 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 20385929 — Predictive Biomarker (PRD): APLNR mRNA
Genes: APLNR; AGTRL1; APJ
Study 14986815 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 2413519 — Surrogate Endpoint (SUR): Serum calcium
Study 31372803 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31372803 — Safety Biomarker (SAF): BDNF
Study 31372803 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27251406 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 27251406 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 27251406 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23359968 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 23359968 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20407369 — Surrogate Endpoint (SUR): Blood pressure
Study 2265765 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7442534 — Surrogate Endpoint (SUR): Blood pressure
Study 30852021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2