TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12358873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12358873 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28031173 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19512978 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19512978 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19512978 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19512978 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16889680 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9269212 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9269212 — Surrogate Endpoint (SUR): Blood pressure
Study 30402206 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22536131 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19696126 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 25586058 — Monitoring Biomarker (MOI): HBV DNA
Study 22426913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31309857 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 31728510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27509063 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 27509063 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 27509063 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27509063 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 7639018 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 31405567 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 29062324 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29062324 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16966109 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18695150 — Surrogate Endpoint (SUR): Blood pressure
Study 18695150 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10678259 — Surrogate Endpoint (SUR): Blood pressure
Study 9222277 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23724618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21095446 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 12639494 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 3318431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9053973 — Surrogate Endpoint (SUR): Serum creatinine
Study 1791771 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1791771 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1791771 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 30772014 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23038758 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 22080794 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11728946 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11728946 — Surrogate Endpoint (SUR): Serum creatinine
Study 24292557 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18975346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11022584 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 2031770 — Monitoring Biomarker (MOI): HBV DNA
Study 16409455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16409455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16409455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19099641 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 1720843 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23274323 — Surrogate Endpoint (SUR): Blood pressure
Study 23274323 — Surrogate Endpoint (SUR): Serum creatinine
Study 19641203 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19641203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19641203 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10668851 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 10668851 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10668851 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10668851 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10668851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10668851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10668851 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9071476 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31702385 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30428890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30428890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27089418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2179477 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2179477 — Predictive Biomarker (PRD): Hormone receptor
Study 23382472 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21409897 — Surrogate Endpoint (SUR): Blood pressure
Study 2938986 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 20720176 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 20720176 — Predictive Biomarker (PRD): MYF6 mRNA
Genes: MYF6; BHLHC4; MRF4
Study 20720176 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 8695026 — Surrogate Endpoint (SUR): Blood pressure
Study 30653086 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22677076 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22677076 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22677076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22677076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17392557 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 17392557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16344837 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 11122690 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20132969 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16871592 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8831922 — Surrogate Endpoint (SUR): Serum testosterone
Study 20220605 — Predictive Biomarker (PRD): ST18 mRNA
Genes: ST18; KIAA0535; ZNF387
Study 20220605 — Predictive Biomarker (PRD): SPA17 mRNA
Genes: SPA17; SP17
Study 19962291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14638493 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 14638493 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 14638493 — Safety Biomarker (SAF): Interleukin 1
Study 28167467 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 10955337 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 1362205 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 24403824 — Surrogate Endpoint (SUR): Blood pressure
Study 14600516 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8645051 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8645051 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8645051 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27321342 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22176629 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17373918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 7605860 — Safety Biomarker (SAF): DRD2
Study 31743300 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8147945 — Surrogate Endpoint (SUR): Blood pressure
Study 3260059 — Surrogate Endpoint (SUR): Blood pressure
Study 19332353 — Surrogate Endpoint (SUR): Blood pressure
Study 25342385 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 23137508 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23137508 — Surrogate Endpoint (SUR): Blood pressure
Study 29960633 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 27157678 — Surrogate Endpoint (SUR): Blood pressure
Study 17239638 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15925031 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 15925031 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15925031 — Surrogate Endpoint (SUR): Blood pressure
Study 9861095 — Safety Biomarker (SAF): Prognostic nutrition index
Study 9861095 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9861095 — Surrogate Endpoint (SUR): Serum creatinine
Study 25100135 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18952538 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 24812072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24812072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20200432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20200432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12780345 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12780345 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27639738 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 24920891 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24920891 — Predictive Biomarker (PRD): S100A4 mRNA
Genes: S100A4; CAPL; MTS1
Study 24920891 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 8788262 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22631049 — Surrogate Endpoint (SUR): Blood pressure
Study 9025767 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 24429305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20690152 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20690152 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 12682335 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10550740 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15507885 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 11331472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11331472 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3681765 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 3681765 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 11319676 — Surrogate Endpoint (SUR): Blood pressure
Study 25362221 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 25362221 — Surrogate Endpoint (SUR): Bone mineral density
Study 2321541 — Surrogate Endpoint (SUR): Blood pressure
Study 23370902 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19189066 — Predictive Biomarker (PRD): SLC25A10 mRNA
Genes: SLC25A10; DIC
Study 14990550 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 21606960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21606960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16350577 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 16350577 — Surrogate Endpoint (SUR): Blood pressure
Study 30501605 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 12799126 — Surrogate Endpoint (SUR): Blood pressure
Study 30170422 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29421218 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 24672938 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19850762 — Predictive Biomarker (PRD): SIGLEC1 mRNA
Genes: SIGLEC1; SN
Study 15764627 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21836540 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16772244 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15471317 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 9269944 — Surrogate Endpoint (SUR): Blood pressure
Study 3661923 — Surrogate Endpoint (SUR): Blood pressure
Study 27265743 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 27265743 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 9129063 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14710100 — Surrogate Endpoint (SUR): Blood pressure
Study 28648567 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 24716668 — Surrogate Endpoint (SUR): Serum antibody concentration
Study 18398972 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7943838 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31044759 — Surrogate Endpoint (SUR): Blood pressure
Study 20796315 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 14714358 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 14714358 — Surrogate Endpoint (SUR): Blood pressure
Study 26305613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26305613 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26305613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30945802 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 23391319 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 15149512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24296871 — Surrogate Endpoint (SUR): Serum uric acid
Study 16636120 — Surrogate Endpoint (SUR): Bone mineral density
Study 14645423 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 14645423 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 1426825 — Surrogate Endpoint (SUR): Blood pressure
Study 8846544 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8846544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8846544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31810940 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 28402454 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 31237713 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 27641967 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25305273 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16932229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11566047 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9740479 — Surrogate Endpoint (SUR): Blood pressure
Study 27102553 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 18511702 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12521408 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 12521408 — Surrogate Endpoint (SUR): Blood pressure
Study 29772131 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 29772131 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 18942713 — Surrogate Endpoint (SUR): Blood pressure
Study 11718213 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22408034 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20580206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19687351 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12623986 — Surrogate Endpoint (SUR): Serum creatinine
Study 8198628 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8198628 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 26962308 — Surrogate Endpoint (SUR): Blood pressure
Study 24905063 — Surrogate Endpoint (SUR): Bone mineral density
Study 22395196 — Surrogate Endpoint (SUR): Serum creatinine
Study 22395196 — Surrogate Endpoint (SUR): Blood pressure
Study 20089489 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7727768 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2201495 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21307846 — Surrogate Endpoint (SUR): Blood pressure
Study 8354335 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2942886 — Surrogate Endpoint (SUR): Blood pressure
Study 18037713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18037713 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9710365 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31900579 — Surrogate Endpoint (SUR): Blood pressure
Study 29223575 — Surrogate Endpoint (SUR): Blood pressure
Study 23832582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23832582 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 21827052 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 11696141 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11696141 — Surrogate Endpoint (SUR): Blood pressure
Study 3390962 — Surrogate Endpoint (SUR): Blood pressure
Study 25816050 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17189218 — Predictive Biomarker (PRD): GGCX mRNA
Genes: GGCX; GC
Study 17189218 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 17189218 — Predictive Biomarker (PRD): CALU mRNA
Genes: CALU
Study 14649215 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7042360 — Surrogate Endpoint (SUR): Blood pressure
Study 28652278 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28652278 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28652278 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 28652278 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 28652278 — Predictive Biomarker (PRD): Hormone receptor
Study 23135760 — Safety Biomarker (SAF): Bacteroides intestinalis
Study 17973945 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19686113 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15077088 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16959024 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 27684290 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27684290 — Surrogate Endpoint (SUR): Blood pressure
Study 27113290 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27113290 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 16096437 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16096437 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16096437 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10211917 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 573246 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 25675199 — Surrogate Endpoint (SUR): Serum creatinine
Study 18074473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8319654 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27978579 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27978579 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 12296782 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 6697637 — Surrogate Endpoint (SUR): Blood pressure
Study 23604641 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 23604641 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB