TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8887592 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1291567 — Surrogate Endpoint (SUR): Sperm parameters
Study 31637821 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17621459 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30743107 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30743107 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 30743107 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 30743107 — Predictive Biomarker (PRD): SLC35A1 mRNA
Genes: SLC35A1
Study 30743107 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 30743107 — Predictive Biomarker (PRD): AQP3 mRNA
Genes: AQP3
Study 30743107 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 30743107 — Predictive Biomarker (PRD): HK2 mRNA
Genes: HK2
Study 30743107 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 30743107 — Predictive Biomarker (PRD): IFNE mRNA
Genes: IFNE; IFNE1; UNQ360/PRO655
Study 30743107 — Predictive Biomarker (PRD): FGF9 mRNA
Genes: FGF9
Study 23945716 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23945716 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1422319 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 20163570 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 16314787 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 15986749 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 30242334 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 25572630 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 25572630 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19910359 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29341850 — Surrogate Endpoint (SUR): Blood pressure
Study 29341850 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19646775 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 15641938 — Surrogate Endpoint (SUR): Blood pressure
Study 12211491 — Safety Biomarker (SAF): Interleukin 1
Study 7852748 — Surrogate Endpoint (SUR): Blood pressure
Study 30036394 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 27366745 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 27366745 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-150
Genes: MIR150
Study 27366745 — Safety Biomarker (SAF): miR-96
Genes: MIR96
Study 2146812 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 31606655 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 31606655 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17920548 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17920548 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 8861661 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 1293307 — Surrogate Endpoint (SUR): Blood pressure
Study 6538006 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 31308344 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 31308344 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31308344 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 31308344 — Safety Biomarker (SAF): Th2 cell
Study 27174596 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27174596 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 8707473 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 29287665 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 27437769 — Predictive Biomarker (PRD): ABCC4 mRNA
Genes: ABCC4; MOATB; MRP4
Study 27437769 — Predictive Biomarker (PRD): GRK3 mRNA
Genes: GRK3; ADRBK2; BARK2
Study 27437769 — Predictive Biomarker (PRD): UHRF1 mRNA
Genes: UHRF1; ICBP90; NP95; RNF106
Study 27437769 — Predictive Biomarker (PRD): ZNF551 mRNA
Genes: ZNF551; KOX23
Study 15809460 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26232169 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26232169 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26232169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26232169 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 26232169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26232169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19404671 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 16490804 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8446653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19763023 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11265775 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 11265775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11265775 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30095791 — Surrogate Endpoint (SUR): Bone mineral density
Study 26687339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26687339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26687339 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 26687339 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20590479 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 10494774 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1672530 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19100282 — Surrogate Endpoint (SUR): Blood pressure
Study 15811058 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7503003 — Surrogate Endpoint (SUR): Blood pressure
Study 27855441 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 24445291 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23559286 — Surrogate Endpoint (SUR): Blood pressure
Study 16436127 — Monitoring Biomarker (MOI): HBV DNA
Study 23067919 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23067919 — Surrogate Endpoint (SUR): Blood pressure
Study 7527406 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28888275 — Surrogate Endpoint (SUR): Blood pressure
Study 18849613 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 18849613 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 18849613 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17156425 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 17156425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29443867 — Surrogate Endpoint (SUR): Bone mineral density
Study 27242317 — Surrogate Endpoint (SUR): Blood pressure
Study 18568272 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15759527 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 31870925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31870925 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9747829 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 7843870 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 24126713 — Surrogate Endpoint (SUR): Blood pressure
Study 16850457 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16146902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11703958 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9394096 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 31744959 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31744959 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26900641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2232659 — Surrogate Endpoint (SUR): Plasma testosterone level
Study 17875971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23403073 — Surrogate Endpoint (SUR): Blood pressure
Study 18156664 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8129764 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28251555 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 15119162 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28512158 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18322413 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 10756221 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 10756221 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10756221 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8334749 — Surrogate Endpoint (SUR): Bone mineral density
Study 27283375 — Surrogate Endpoint (SUR): Blood pressure
Study 11434164 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19473593 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19473593 — Surrogate Endpoint (SUR): Blood pressure
Study 26049689 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 28639369 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 28639369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28639369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23249532 — Surrogate Endpoint (SUR): Serum creatinine
Study 21481147 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 19500141 — Surrogate Endpoint (SUR): Serum creatinine
Study 27647856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26084693 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 26084693 — Surrogate Endpoint (SUR): Blood pressure
Study 19185645 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19185645 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19185645 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19185645 — Surrogate Endpoint (SUR): Blood pressure
Study 14692989 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3526627 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20531232 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 15955241 — Predictive Biomarker (PRD): SERPINH1 mRNA
Genes: SERPINH1; CBP1; CBP2; HSP47; SERPINH2; PIG14
Study 10598520 — Predictive Biomarker (PRD): EHF mRNA
Genes: EHF; ESE3; ESE3B; ESEJ
Study 25054387 — Predictive Biomarker (PRD): SERPINA2 mRNA
Genes: SERPINA2; ARGS; ATR; PIL; SERPINA2P
Study 15795426 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 15795426 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11959049 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29046301 — Surrogate Endpoint (SUR): Bone mineral density
Study 17521544 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14725484 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 14725484 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8124802 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8124802 — Surrogate Endpoint (SUR): Blood pressure
Study 31566680 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31566680 — Predictive Biomarker (PRD): Hormone receptor
Study 20971747 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20971747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3117403 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 29424469 — Surrogate Endpoint (SUR): Blood pressure
Study 20842418 — Safety Biomarker (SAF): Hyaluronic acid
Study 14673985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29102571 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22295826 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 10190653 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10190653 — Surrogate Endpoint (SUR): Blood pressure
Study 19101227 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19101227 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9669009 — Surrogate Endpoint (SUR): Blood pressure
Study 17199098 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9138543 — Surrogate Endpoint (SUR): Blood pressure
Study 8709213 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22535269 — Surrogate Endpoint (SUR): Blood pressure
Study 19433070 — Predictive Biomarker (PRD): CPOX mRNA
Genes: CPOX; CPO; CPX
Study 26547109 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 11001892 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6141051 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6141051 — Surrogate Endpoint (SUR): Blood pressure
Study 27375066 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 17659942 — Surrogate Endpoint (SUR): Blood pressure
Study 11861267 — Safety Biomarker (SAF): Reactive oxygen species
Study 31831574 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22875659 — Surrogate Endpoint (SUR): Serum creatinine
Study 15333723 — Surrogate Endpoint (SUR): Blood pressure
Study 30613999 — Surrogate Endpoint (SUR): Blood pressure
Study 21747002 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 28743247 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26158573 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 7575710 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 7575710 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16052108 — Surrogate Endpoint (SUR): Blood pressure
Study 19793378 — Surrogate Endpoint (SUR): Serum testosterone
Study 2818394 — Surrogate Endpoint (SUR): Blood pressure
Study 46963 — Surrogate Endpoint (SUR): Serum calcium
Study 25577471 — Surrogate Endpoint (SUR): Blood pressure
Study 21726916 — Surrogate Endpoint (SUR): Serum creatinine
Study 14559317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14559317 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10812331 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 1509401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1509401 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1962599 — Predictive Biomarker (PRD): Hormone receptor
Study 26651453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19680279 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 16421365 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30102965 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 24901463 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10698385 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17490928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11833827 — Surrogate Endpoint (SUR): Blood pressure
Study 11833827 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8625624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 24135509 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23901023 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 23901023 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 23901023 — Predictive Biomarker (PRD): ADAM10 mRNA
Genes: ADAM10; KUZ; MADM
Study 20948453 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 18303408 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 25024070 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22967970 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22967970 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22967970 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 1693173 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25801761 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23480506 — Surrogate Endpoint (SUR): Serum calcium
Study 23480506 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26043651 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 12209517 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12209517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12209517 — Surrogate Endpoint (SUR): Serum creatinine
Study 16869933 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2053453 — Surrogate Endpoint (SUR): Blood pressure
Study 26930571 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15896247 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31486004 — Surrogate Endpoint (SUR): Blood pressure
Study 16634952 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 16634952 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12632341 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 31869430 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31869430 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27733219 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 24534763 — Surrogate Endpoint (SUR): Serum creatinine
Study 18564806 — Surrogate Endpoint (SUR): Blood pressure
Study 10957661 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 6383692 — Surrogate Endpoint (SUR): Blood pressure
Study 18503492 — Surrogate Endpoint (SUR): Bone mineral density
Study 17687925 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11673813 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29405635 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20392617 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20392617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20392617 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19346113 — Surrogate Endpoint (SUR): Blood pressure
Study 19346113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19346113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19346113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24267040 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17577103 — Surrogate Endpoint (SUR): Blood pressure
Study 31605113 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27756788 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 12742981 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12742981 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10694896 — Surrogate Endpoint (SUR): Blood pressure
Study 29524621 — Predictive Biomarker (PRD): SIGLEC1 mRNA
Genes: SIGLEC1; SN
Study 24446590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24446590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9625686 — Surrogate Endpoint (SUR): Bone mineral density
Study 9509822 — Surrogate Endpoint (SUR): Bone mineral density
Study 4054138 — Surrogate Endpoint (SUR): Blood pressure
Study 26852290 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26852290 — Surrogate Endpoint (SUR): Blood pressure
Study 20438539 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 2013178 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29203355 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 9186538 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2418302 — Surrogate Endpoint (SUR): Blood pressure
Study 21570659 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 18812844 — Surrogate Endpoint (SUR): Blood pressure
Study 17181880 — Surrogate Endpoint (SUR): Serum testosterone
Study 12709722 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20377476 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21133303 — Surrogate Endpoint (SUR): Blood pressure
Study 22470539 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 10839585 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9175045 — Surrogate Endpoint (SUR): Blood pressure
Study 3921124 — Surrogate Endpoint (SUR): Blood pressure
Study 2853194 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26289682 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 21936956 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF