TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27232884 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27232884 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27232884 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23997107 — Surrogate Endpoint (SUR): Blood pressure
Study 8806342 — Surrogate Endpoint (SUR): Blood pressure
Study 31056784 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29961059 — Surrogate Endpoint (SUR): Blood pressure
Study 29961059 — Surrogate Endpoint (SUR): Serum creatinine
Study 16988198 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 2244710 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study 2244710 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31129917 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19464613 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 19464613 — Surrogate Endpoint (SUR): Blood pressure
Study 11566639 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 8154486 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18583464 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18583464 — Surrogate Endpoint (SUR): Blood pressure
Study 18583464 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11802244 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 28992192 — Surrogate Endpoint (SUR): Blood pressure
Study 21845341 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21845341 — Surrogate Endpoint (SUR): Blood pressure
Study 8894937 — Surrogate Endpoint (SUR): Blood pressure
Study 2003079 — Surrogate Endpoint (SUR): Blood pressure
Study 6152120 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 25461390 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9250136 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9250136 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9250136 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 26630989 — Predictive Biomarker (PRD): ROCK2 mRNA
Genes: ROCK2; KIAA0619
Study 18427001 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18427001 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 12859445 — Predictive Biomarker (PRD): SCGB3A2 mRNA
Genes: SCGB3A2; PNSP1; UGRP1; UNQ566/PRO1128
Study 24588936 — Surrogate Endpoint (SUR): Serum uric acid
Study 17945530 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17945530 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 2199131 — Surrogate Endpoint (SUR): Blood pressure
Study 2278166 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2278166 — Surrogate Endpoint (SUR): Blood pressure
Study 2278166 — Surrogate Endpoint (SUR): Serum creatinine
Study 2278166 — Surrogate Endpoint (SUR): Serum sodium
Study 23541376 — Surrogate Endpoint (SUR): Blood pressure
Study 23541376 — Surrogate Endpoint (SUR): Serum creatinine
Study 2059393 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2059393 — Surrogate Endpoint (SUR): Blood pressure
Study 26043560 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26043560 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23690237 — Surrogate Endpoint (SUR): Blood pressure
Study 21593661 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 21593661 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21593661 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16945057 — Surrogate Endpoint (SUR): Blood pressure
Study 15261317 — Surrogate Endpoint (SUR): Blood pressure
Study 3159547 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 3159547 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3159547 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3159547 — Surrogate Endpoint (SUR): Serum testosterone
Study 29043412 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23279860 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16141377 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 29020193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29020193 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26602006 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 26602006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26602006 — Safety Biomarker (SAF): Reactive oxygen species
Study 26602006 — Surrogate Endpoint (SUR): Serum creatinine
Study 23529570 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 10965198 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 28698243 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 18637718 — Surrogate Endpoint (SUR): Bacterial count
Study 10928228 — Surrogate Endpoint (SUR): Bone mineral density
Study 9295593 — Surrogate Endpoint (SUR): Serum creatinine
Study 20653798 — Surrogate Endpoint (SUR): Blood pressure
Study 24858921 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 24858921 — Predictive Biomarker (PRD): TMEM97 mRNA
Genes: TMEM97; MAC30; S2R
Study 20179751 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20179751 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 16052109 — Surrogate Endpoint (SUR): Blood pressure
Study 30422368 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24502859 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 20829497 — Surrogate Endpoint (SUR): Blood pressure
Study 15843081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8270459 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25659979 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 25659979 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24120179 — Surrogate Endpoint (SUR): Blood pressure
Study 17085376 — Surrogate Endpoint (SUR): Blood pressure
Study 10916100 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10916100 — Surrogate Endpoint (SUR): Blood pressure
Study 10916100 — Surrogate Endpoint (SUR): Serum uric acid
Study 1325762 — Surrogate Endpoint (SUR): Bone mineral density
Study 1325762 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 6363096 — Surrogate Endpoint (SUR): Blood pressure
Study 6363096 — Surrogate Endpoint (SUR): Serum potassium
Study 30885955 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 30885955 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30885955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21253373 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 21253373 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21253373 — Surrogate Endpoint (SUR): Blood pressure
Study 9651908 — Surrogate Endpoint (SUR): Bone mineral density
Study 25786050 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 23924790 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21133742 — Surrogate Endpoint (SUR): Blood pressure
Study 11895067 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31787150 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31787150 — Safety Biomarker (SAF): BDNF
Study 25241271 — Surrogate Endpoint (SUR): Blood pressure
Study 15075878 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 9394313 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9394313 — Surrogate Endpoint (SUR): Blood pressure
Study 9394313 — Surrogate Endpoint (SUR): Serum uric acid
Study 27737692 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23497109 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 17426001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9208360 — Surrogate Endpoint (SUR): Blood pressure
Study 31990936 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21703806 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1649497 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 1649497 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28595464 — Surrogate Endpoint (SUR): Blood pressure
Study 25281894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25281894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25281894 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10999783 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 8852910 — Monitoring Biomarker (MOI): HBV DNA
Study 30439316 — Surrogate Endpoint (SUR): Blood pressure
Study 18345549 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3100871 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27936214 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 15896421 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30759089 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 30759089 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 26936519 — Surrogate Endpoint (SUR): Blood pressure
Study 26936519 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22144699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8866899 — Surrogate Endpoint (SUR): Blood pressure
Study 31120518 — Predictive Biomarker (PRD): IGFBP6 mRNA
Genes: IGFBP6; IBP6
Study 31120518 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study 27859252 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21250901 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11577946 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 9698961 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30835573 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30835573 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26081765 — Surrogate Endpoint (SUR): Blood pressure
Study 18359280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18359280 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11303724 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2572260 — Surrogate Endpoint (SUR): Blood pressure
Study 21843921 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21843921 — Surrogate Endpoint (SUR): Pathological complete response
Study 31142254 — Predictive Biomarker (PRD): COG2 mRNA
Genes: COG2; LDLC
Study 31142254 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31142254 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28489465 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26517214 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 26517214 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 21084763 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 21084763 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21084763 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 3034757 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 3034757 — Surrogate Endpoint (SUR): Blood pressure
Study 15555666 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9131679 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 8198026 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31799981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31799981 — Predictive Biomarker (PRD): GPX4 mRNA
Genes: GPX4
Study 29368212 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 29368212 — Predictive Biomarker (PRD): MLH3 mRNA
Genes: MLH3
Study 29368212 — Predictive Biomarker (PRD): RAD21 mRNA
Genes: RAD21; HR21; KIAA0078; NXP1; SCC1
Study 29368212 — Predictive Biomarker (PRD): SMC4 mRNA
Genes: SMC4; CAPC; SMC4L1
Study 24979303 — Surrogate Endpoint (SUR): Blood pressure
Study 24979303 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22248497 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17395393 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17395393 — Surrogate Endpoint (SUR): Blood pressure
Study 9891943 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 26046730 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23044498 — Surrogate Endpoint (SUR): Blood pressure
Study 15863204 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 10726111 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10726111 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10726111 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 14733779 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11282177 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23181790 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23181790 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 23181790 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 23181790 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 23181790 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 15707951 — Predictive Biomarker (PRD): NOS1AP mRNA
Genes: NOS1AP; CAPON; KIAA0464
Study 10589806 — Surrogate Endpoint (SUR): Probing pocket depth
Study 1755555 — Surrogate Endpoint (SUR): Blood pressure
Study 28560655 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8023998 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 28791521 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 24119989 — Surrogate Endpoint (SUR): Blood pressure
Study 20555276 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 2069490 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27179731 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15817595 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15817595 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12226607 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 10374174 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 16740843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8302395 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8302395 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 8302395 — Surrogate Endpoint (SUR): Blood pressure
Study 21558457 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 19616987 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 23866835 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23866835 — Surrogate Endpoint (SUR): Serum creatinine
Study 21359104 — Surrogate Endpoint (SUR): Blood pressure
Study 30937304 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 25597529 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 23438483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23438483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8610312 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30678193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30678193 — Surrogate Endpoint (SUR): Blood pressure
Study 30678193 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28361746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28361746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28361746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16461817 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 9447368 — Surrogate Endpoint (SUR): Blood pressure
Study 29630549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26562046 — Surrogate Endpoint (SUR): Blood pressure
Study 24068048 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21417560 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21417560 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21417560 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21417560 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16988930 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 16988930 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 31245842 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16827869 — Surrogate Endpoint (SUR): Serum creatinine
Study 10921706 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 11159252 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8297542 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8297542 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3443128 — Surrogate Endpoint (SUR): Blood pressure
Study 31246109 — Surrogate Endpoint (SUR): Blood pressure
Study 16129715 — Surrogate Endpoint (SUR): Blood pressure
Study 22542709 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16326006 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 25565669 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 25565669 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23559222 — Surrogate Endpoint (SUR): Blood pressure
Study 23559222 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 15901043 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15901043 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15901043 — Surrogate Endpoint (SUR): Blood pressure
Study 12687534 — Safety Biomarker (SAF): Interleukin 1
Study 25316469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17278988 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17278988 — Surrogate Endpoint (SUR): Blood pressure
Study 11863247 — Surrogate Endpoint (SUR): Blood pressure
Study 31912391 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 29482525 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 17012900 — Monitoring Biomarker (MOI): HBV DNA
Study 10757582 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3532763 — Surrogate Endpoint (SUR): Serum antibody concentration
Study 29593013 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 29593013 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 29593013 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 29593013 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27538423 — Surrogate Endpoint (SUR): Blood pressure
Study 27538423 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22717177 — Predictive Biomarker (PRD): NKRF mRNA
Genes: NKRF; ITBA4; NRF
Study 20298928 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25663125 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 18638266 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 17380846 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 17380846 — Surrogate Endpoint (SUR): Blood pressure
Study 10809917 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10809917 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8646827 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6500225 — Surrogate Endpoint (SUR): Blood pressure
Study 19366848 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 26002840 — Surrogate Endpoint (SUR): Blood pressure
Study 23344779 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11672921 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27212005 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 22302136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20201949 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 9376241 — Surrogate Endpoint (SUR): Blood pressure
Study 27194308 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 22974788 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22974788 — Surrogate Endpoint (SUR): Blood pressure
Study 26778544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24266855 — Surrogate Endpoint (SUR): Serum creatinine
Study 3516511 — Surrogate Endpoint (SUR): Blood pressure
Study 30304013 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study 12587093 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 14724827 — Monitoring Biomarker (MOI): HBV DNA
Study 1426218 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2861738 — Surrogate Endpoint (SUR): Blood pressure
Study 10780315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10780315 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1