TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29137107 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29137107 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 29137107 — Surrogate Endpoint (SUR): Bone mineral density
Study 29137107 — Surrogate Endpoint (SUR): Serum calcium
Study 22552048 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 22552048 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31314967 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10195319 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 10195319 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 6656327 — Surrogate Endpoint (SUR): Blood pressure
Study 31442936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26864309 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 26864309 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study 17268215 — Surrogate Endpoint (SUR): Blood pressure
Study 7477167 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7013060 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31163212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30053031 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30053031 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30053031 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 30053031 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 6795049 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 22257523 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22257523 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22257523 — Predictive Biomarker (PRD): Hormone receptor
Study 12238823 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7914733 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7914733 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24766732 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18668408 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18668408 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28125168 — Surrogate Endpoint (SUR): Sperm parameters
Study 23312881 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9151028 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7903975 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3153025 — Surrogate Endpoint (SUR): Serum creatinine
Study 3513667 — Surrogate Endpoint (SUR): Serum potassium
Study 26857646 — Predictive Biomarker (PRD): ACSM1 mRNA
Genes: ACSM1; BUCS1; LAE; MACS1
Study 26857646 — Predictive Biomarker (PRD): AMACR mRNA
Genes: AMACR
Study 26857646 — Predictive Biomarker (PRD): CACNA1D mRNA
Genes: CACNA1D; CACH3; CACN4; CACNL1A2; CCHL1A2
Study 26857646 — Predictive Biomarker (PRD): DLX1 mRNA
Genes: DLX1
Study 26857646 — Predictive Biomarker (PRD): KLK3 mRNA
Genes: KLK3; APS
Study 26857646 — Predictive Biomarker (PRD): PLA2G7 mRNA
Genes: PLA2G7; PAFAH
Study 26857646 — Predictive Biomarker (PRD): RHOU mRNA
Genes: RHOU; ARHU; CDC42L1; G28K; WRCH1; SB128
Study 26857646 — Predictive Biomarker (PRD): SPINK1 mRNA
Genes: SPINK1; PSTI
Study 26857646 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 26857646 — Predictive Biomarker (PRD): TDRD1 mRNA
Genes: TDRD1
Study 12218725 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12218725 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12218725 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7557852 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 21288121 — Predictive Biomarker (PRD): ENPP2 mRNA
Genes: ENPP2; ATX; PDNP2
Study 15088884 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 12208482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12208482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12208482 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12208482 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 1858760 — Surrogate Endpoint (SUR): Blood pressure
Study 21246575 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 10739631 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 24641941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24641941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24641941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19693550 — Surrogate Endpoint (SUR): Bacterial count
Study 17959861 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10613628 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 7159883 — Surrogate Endpoint (SUR): Blood pressure
Study 25185754 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31286728 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 10608948 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30789386 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 9424977 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30256919 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 30256919 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19297430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11161898 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 16093403 — Surrogate Endpoint (SUR): Blood pressure
Study 16093403 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 7792016 — Surrogate Endpoint (SUR): Serum uric acid
Study 26487585 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 8959628 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8959628 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18062586 — Surrogate Endpoint (SUR): Serum calcium
Study 10574605 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 10574605 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 19536889 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11770031 — Safety Biomarker (SAF): IL-6 and IL-10
Study 11770031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2829953 — Surrogate Endpoint (SUR): Blood pressure
Study 15692069 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 10068658 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31913961 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 27125966 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 27125966 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20668324 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16320974 — Surrogate Endpoint (SUR): Blood pressure
Study 16363278 — Predictive Biomarker (PRD): PRF1
Genes: PFP; P1; HPLH2
Study 16363278 — Surrogate Endpoint (SUR): Blood pressure
Study 11573666 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1586105 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1586105 — Surrogate Endpoint (SUR): Serum testosterone
Study 1586105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31783900 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 6420959 — Surrogate Endpoint (SUR): Serum creatinine
Study 17660154 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15855335 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24513094 — Surrogate Endpoint (SUR): Blood pressure
Study 22452789 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22452789 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2178643 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27759898 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 26423650 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23507186 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 19418213 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CHRM2 mRNA
Genes: CHRM2
Study 25118597 — Surrogate Endpoint (SUR): Bone mineral density
Study 23554756 — Surrogate Endpoint (SUR): Blood pressure
Study 19410716 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15127083 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 28629318 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 9219211 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17323547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10922234 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 10922234 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1506791 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25344520 — Predictive Biomarker (PRD): HDGFL2 mRNA
Genes: HDGFL2; HDGF2; HDGFRP2; HRP2; UNQ785/PRO1604
Study 25135348 — Predictive Biomarker (PRD): NOTCH2 mRNA
Genes: NOTCH2
Study 25135348 — Predictive Biomarker (PRD): C2CD4B mRNA
Genes: C2CD4B; FAM148B; NLF2
Study 25135348 — Predictive Biomarker (PRD): SLC30A8 mRNA
Genes: SLC30A8; ZNT8
Study 25135348 — Predictive Biomarker (PRD): SEC61A2 mRNA
Genes: SEC61A2
Study 10977126 — Surrogate Endpoint (SUR): Blood pressure
Study 28327140 — Surrogate Endpoint (SUR): Blood pressure
Study 27701496 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 24067879 — Surrogate Endpoint (SUR): Serum creatinine
Study 14703417 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 3921279 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31007691 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26636393 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 26636393 — Surrogate Endpoint (SUR): Serum creatinine
Study 2007326 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2007326 — Surrogate Endpoint (SUR): Blood pressure
Study 31420350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28829488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28829488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28829488 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28481761 — Surrogate Endpoint (SUR): Blood pressure
Study 15526380 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 15526380 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10740417 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 10740417 — Surrogate Endpoint (SUR): Blood pressure
Study 1778192 — Surrogate Endpoint (SUR): Blood pressure
Study 31029154 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 26698157 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 25239028 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 23114134 — Surrogate Endpoint (SUR): Bone mineral density
Study 17721099 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22885913 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 21850690 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19644398 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 12575553 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9597406 — Surrogate Endpoint (SUR): Blood pressure
Study 25541227 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8675921 — Surrogate Endpoint (SUR): Bone mineral density
Study 6396365 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 6396365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 6396365 — Safety Biomarker (SAF): Glutamate dehydrogenase
Study 26825278 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 24657991 — Surrogate Endpoint (SUR): Blood pressure
Study 11463590 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 173124 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19207889 — Surrogate Endpoint (SUR): Probing pocket depth
Study 9677811 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7793393 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19602786 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9825973 — Surrogate Endpoint (SUR): Serum calcium
Study 656270 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16955801 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29996127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23730881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18394060 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16152824 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12211224 — Surrogate Endpoint (SUR): Blood pressure
Study 10761326 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8797513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25483700 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25483700 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20400899 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16083996 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 12442956 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9809623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18343245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18343245 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12784090 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 17823506 — Surrogate Endpoint (SUR): Serum creatinine
Study 12463460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12463460 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 10516691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10516691 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10516691 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 21938072 — Surrogate Endpoint (SUR): Blood pressure
Study 31861026 — Surrogate Endpoint (SUR): Blood pressure
Study 17079994 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2751476 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25987796 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21466598 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21466598 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21466598 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28851037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27662556 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12213870 — Surrogate Endpoint (SUR): Sperm parameters
Study 25399552 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 22152871 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 11413357 — Surrogate Endpoint (SUR): Blood pressure
Study 9404429 — Surrogate Endpoint (SUR): Blood pressure
Study 8236548 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 8236548 — Surrogate Endpoint (SUR): Serum creatinine
Study 26968380 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 26968380 — Safety Biomarker (SAF): Cardiac troponin T
Genes: TNNT2
Study 15761191 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 12454555 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 6108592 — Surrogate Endpoint (SUR): Blood pressure
Study 23959833 — Predictive Biomarker (PRD): MTRR mRNA
Genes: MTRR
Study 23959833 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 23959833 — Safety Biomarker (SAF): MTHFR
Study 19584831 — Monitoring Biomarker (MOI): HBV DNA
Study 27330807 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 18300236 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 18300236 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18300236 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 12796772 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12796772 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11195956 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 7840401 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22884532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21481414 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 15938534 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15938534 — Surrogate Endpoint (SUR): Blood pressure
Study 10369282 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2310248 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30641712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9923765 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 9923765 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9923765 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9923765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 29273661 — Surrogate Endpoint (SUR): Blood pressure
Study 29273661 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9686497 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26109470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9404251 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 3099651 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 26982618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26982618 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22394534 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 22394534 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 19294859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19294859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19294859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7475139 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27111239 — Surrogate Endpoint (SUR): Bone mineral density
Study 10480411 — Surrogate Endpoint (SUR): Bone mineral density
Study 10480411 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 6958191 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6958191 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 6958191 — Surrogate Endpoint (SUR): Blood pressure
Study 15044205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 15044205 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 15044205 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15044205 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 20501957 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 11120523 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 26822146 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26822146 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19458961 — Surrogate Endpoint (SUR): Blood pressure
Study 14726297 — Surrogate Endpoint (SUR): Blood pressure
Study 11206672 — Surrogate Endpoint (SUR): Blood pressure
Study 30018118 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 30018118 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC