TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16733169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16733169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10421835 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 23102798 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 20576732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10466476 — Surrogate Endpoint (SUR): Blood pressure
Study 26692201 — Predictive Biomarker (PRD): NRN1 mRNA
Genes: NRN1; NRN
Study 31613323 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19427372 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 9249109 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 9249109 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8493215 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20417770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27751553 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14742379 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11167376 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 9459625 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7949265 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 17287313 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 9880125 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9880125 — Surrogate Endpoint (SUR): Blood pressure
Study 21925749 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21925749 — Surrogate Endpoint (SUR): Blood pressure
Study 21925749 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21925749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22673924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11444416 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28685353 — Predictive Biomarker (PRD): TSPAN12 mRNA
Genes: TSPAN12; NET2; TM4SF12; UNQ774/PRO1568
Study 22922803 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22922803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7730651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7730651 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 7730651 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7730651 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 20152345 — Surrogate Endpoint (SUR): Blood pressure
Study 30060746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30060746 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 30060746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30060746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31292955 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study 20368567 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 24770560 — Surrogate Endpoint (SUR): Blood pressure
Study 20609991 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 20609991 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 15817593 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2137901 — Surrogate Endpoint (SUR): Blood pressure
Study 20491816 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16150199 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16150199 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 10197493 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 19114612 — Surrogate Endpoint (SUR): Serum uric acid
Study 19114612 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 11028725 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8068603 — Surrogate Endpoint (SUR): Blood pressure
Study 29396978 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23698074 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23698074 — Surrogate Endpoint (SUR): Serum creatinine
Study 25779558 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20966402 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20966402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22795088 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 22795088 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22795088 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 19625946 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16539642 — Surrogate Endpoint (SUR): Serum creatinine
Study 8176999 — Surrogate Endpoint (SUR): Blood pressure
Study 24560332 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12205570 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16424411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11063148 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 9060533 — Surrogate Endpoint (SUR): Bone mineral density
Study 21171265 — Surrogate Endpoint (SUR): Serum sodium
Study 31792640 — Surrogate Endpoint (SUR): Serum uric acid
Study 19655666 — Predictive Biomarker (PRD): RAD1 mRNA
Genes: RAD1; REC1
Study 19655666 — Predictive Biomarker (PRD): FEN1 mRNA
Genes: FEN1; RAD2
Study 16728521 — Surrogate Endpoint (SUR): Blood pressure
Study 11303007 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11303007 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11303007 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26447752 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23052606 — Surrogate Endpoint (SUR): Bone mineral density
Study 16826026 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 14520724 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30725192 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study 17987533 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 12173299 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12173299 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 12173299 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 12173299 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12173299 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 10463407 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 28068786 — Surrogate Endpoint (SUR): Serum creatinine
Study 17101936 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30879186 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25552372 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17353778 — Surrogate Endpoint (SUR): Serum creatinine
Study 17353778 — Surrogate Endpoint (SUR): Blood pressure
Study 8154506 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21876297 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 30148437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26617438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26617438 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25096178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22531635 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 18214123 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 26932169 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20969659 — Safety Biomarker (SAF): Hyaluronic acid
Study 19679266 — Surrogate Endpoint (SUR): Blood pressure
Study 8143828 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30368884 — Predictive Biomarker (PRD): TWIST1 mRNA
Genes: TWIST1; BHLHA38; TWIST
Study 30368884 — Predictive Biomarker (PRD): SNAI2 mRNA
Genes: SNAI2; SLUG; SLUGH
Study 24493829 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24493829 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 31735613 — Safety Biomarker (SAF): Hyaluronic acid
Study 28831752 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 25281755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25281755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19645964 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 14731173 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8355505 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 20815183 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 11956450 — Surrogate Endpoint (SUR): Bone mineral density
Study 25844821 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21851299 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21851299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8637402 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8637402 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 8637402 — Predictive Biomarker (PRD): MSH4 mRNA
Genes: MSH4
Study 1595533 — Surrogate Endpoint (SUR): Blood pressure
Study 3927332 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3927332 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 24072231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14602771 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14602771 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23680248 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23680248 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23680248 — Surrogate Endpoint (SUR): Blood pressure
Study 25561293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 14992881 — Surrogate Endpoint (SUR): Serum calcium
Study 3322670 — Surrogate Endpoint (SUR): Blood pressure
Study 18349395 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8933485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24114865 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 7380584 — Surrogate Endpoint (SUR): Blood pressure
Study 22840783 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15331679 — Surrogate Endpoint (SUR): Blood pressure
Study 11247108 — Surrogate Endpoint (SUR): Blood pressure
Study 30196968 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 15254055 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 11480629 — Surrogate Endpoint (SUR): Blood pressure
Study 21248183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21248183 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18978177 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 18978177 — Predictive Biomarker (PRD): GADD45A mRNA
Genes: GADD45A; DDIT1; GADD45
Study 30864279 — Surrogate Endpoint (SUR): Bone mineral density
Study 30864279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21148423 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 21148423 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study 21148423 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21148423 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 18991190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7939369 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28882920 — Surrogate Endpoint (SUR): Blood pressure
Study 10878675 — Surrogate Endpoint (SUR): Blood pressure
Study 8932264 — Surrogate Endpoint (SUR): Serum creatinine
Study 27776442 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 27776442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27776442 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25012003 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31574151 — Monitoring Biomarker (MOI): HBV DNA
Study 26787567 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 26787567 — Surrogate Endpoint (SUR): Serum creatinine
Study 19584820 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16080839 — Surrogate Endpoint (SUR): Blood pressure
Study 23542157 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23542157 — Surrogate Endpoint (SUR): Blood pressure
Study 15316843 — Surrogate Endpoint (SUR): Blood pressure
Study 11941377 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 2587847 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 2587847 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 16918719 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16918719 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 25391864 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 25391864 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 17049662 — Surrogate Endpoint (SUR): Blood pressure
Study 11484098 — Surrogate Endpoint (SUR): Bone mineral density
Study 2742469 — Predictive Biomarker (PRD): ANTXR1 mRNA
Genes: ANTXR1; ATR; TEM8
Study 18973027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14762035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26174323 — Predictive Biomarker (PRD): NCAM1 mRNA
Genes: NCAM1; NCAM
Study 14693162 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14693162 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31594032 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 26864356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25270680 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 20814119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2205342 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30452127 — Predictive Biomarker (PRD): RARS1 mRNA
Genes: RARS1; RARS
Study 27973337 — Surrogate Endpoint (SUR): Blood pressure
Study 26015372 — Surrogate Endpoint (SUR): Serum creatinine
Study 9143014 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 21685549 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12782903 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12782903 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1890517 — Surrogate Endpoint (SUR): Blood pressure
Study 19403640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9536226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9536226 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19622117 — Monitoring Biomarker (MOI): HBV DNA
Study 18614945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8198024 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3295315 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3295315 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19145638 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17306441 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26481198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26200237 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26200237 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 23549954 — Surrogate Endpoint (SUR): Bone mineral density
Study 19394939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19394939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19660910 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23889363 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 4065193 — Surrogate Endpoint (SUR): Blood pressure
Study 31859706 — Predictive Biomarker (PRD): RAB8A mRNA
Genes: RAB8A; MEL; RAB8
Study 21285287 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 15131541 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 2147631 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2147631 — Surrogate Endpoint (SUR): Blood pressure
Study 30932719 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 28402342 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21450643 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21450643 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30367939 — Surrogate Endpoint (SUR): Bone mineral density
Study 30367939 — Surrogate Endpoint (SUR): Serum calcium
Study 30367939 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 30367939 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 21183747 — Surrogate Endpoint (SUR): Blood pressure
Study 14734123 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14734123 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 14734123 — Surrogate Endpoint (SUR): Blood pressure
Study 11452711 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11452711 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29389738 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29389738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29389738 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29389738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29389738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29389738 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27437724 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 25743829 — Predictive Biomarker (PRD): Microsatellite instability
Study 1335012 — Surrogate Endpoint (SUR): Blood pressure
Study 15813810 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 15813810 — Predictive Biomarker (PRD): GNL3 mRNA
Genes: GNL3; E2IG3; NS
Study 15813810 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 12154417 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 11800061 — Surrogate Endpoint (SUR): Blood pressure
Study 17304419 — Predictive Biomarker (PRD): SLC22A4 mRNA
Genes: SLC22A4; ETT; OCTN1; UT2H
Study 11140366 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30646140 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 27282261 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 18815815 — Surrogate Endpoint (SUR): Total kidney volume
Study 26912554 — Surrogate Endpoint (SUR): Serum creatinine
Study 10051494 — Monitoring Biomarker (MOI): HBV DNA
Study 2147377 — Surrogate Endpoint (SUR): Blood pressure
Study 28574779 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25651246 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 24280470 — Surrogate Endpoint (SUR): Blood pressure
Study 21453540 — Surrogate Endpoint (SUR): Blood pressure
Study 9618753 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 9098473 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 3741249 — Surrogate Endpoint (SUR): Blood pressure
Study 16629292 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24597619 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 18842771 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 16102616 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11847518 — Predictive Biomarker (PRD): Microsatellite instability