TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23461841 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3299090 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3299090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 18187744 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 18187744 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 8352673 — Surrogate Endpoint (SUR): Blood pressure
Study 26024110 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9669432 — Surrogate Endpoint (SUR): Blood pressure
Study 30143705 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-143
Genes: MIR143
Study 12828863 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12828863 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12828863 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2005733 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30237505 — Surrogate Endpoint (SUR): Bone mineral density
Study 30237505 — Surrogate Endpoint (SUR): Serum calcium
Study 26773778 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26773778 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 26773778 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 26773778 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26773778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20534325 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15863374 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8717471 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 1648598 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 10802151 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10802151 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10802151 — Surrogate Endpoint (SUR): Blood pressure
Study 8858389 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 8858389 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 8858389 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 1353368 — Surrogate Endpoint (SUR): Blood pressure
Study 6143631 — Surrogate Endpoint (SUR): Serum potassium
Study 30235680 — Surrogate Endpoint (SUR): Blood pressure
Study 30235680 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24559858 — Surrogate Endpoint (SUR): Serum creatinine
Study 20620037 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15855216 — Predictive Biomarker (PRD): GLI2 mRNA
Genes: GLI2; THP
Study 15855216 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11939671 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11939671 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30239824 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30239824 — Predictive Biomarker (PRD): Hormone receptor
Study 16269184 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8422279 — Surrogate Endpoint (SUR): Pathological complete response
Study 21073697 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8759812 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29912357 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17283264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17283264 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15197541 — Surrogate Endpoint (SUR): Bone mineral density
Study 2031076 — Surrogate Endpoint (SUR): Blood pressure
Study 2031076 — Surrogate Endpoint (SUR): Serum potassium
Study 23696855 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 27340919 — Surrogate Endpoint (SUR): Blood pressure
Study 23064592 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 8777336 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8777336 — Surrogate Endpoint (SUR): Blood pressure
Study 29249596 — Surrogate Endpoint (SUR): Blood pressure
Study 12925454 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 29528793 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29528793 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24335106 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24335106 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 31755625 — Surrogate Endpoint (SUR): Blood pressure
Study 24624861 — Surrogate Endpoint (SUR): Serum sodium
Study 20921019 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16157899 — Pharmacodynamic Biomarker (PDY): Peripheral myelin protein 22
Genes: PMP22; GAS3
Study 12960539 — Surrogate Endpoint (SUR): Blood pressure
Study 10469854 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8896312 — Surrogate Endpoint (SUR): Blood pressure
Study 22452841 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 12111046 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22404668 — Surrogate Endpoint (SUR): Blood pressure
Study 19938151 — Surrogate Endpoint (SUR): Bone mineral density
Study 19099975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7872875 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 31618176 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27748083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23482645 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21490144 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 7997846 — Surrogate Endpoint (SUR): Blood pressure
Study 7997846 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30506302 — Surrogate Endpoint (SUR): Bone mineral density
Study 23794185 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 23794185 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 21849912 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 19641928 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 19641928 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 17118480 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 15001324 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 28966223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28489239 — Safety Biomarker (SAF): Hyaluronic acid
Study 17481748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17481748 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17481748 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 24378268 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 17273672 — Surrogate Endpoint (SUR): Blood pressure
Study 4025792 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 26043861 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 18049093 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 12829523 — Surrogate Endpoint (SUR): Blood pressure
Study 6760236 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31576438 — Surrogate Endpoint (SUR): Blood pressure
Study 30684340 — Surrogate Endpoint (SUR): Blood pressure
Study 17437242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17437242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17437242 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 31280967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24714776 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 17590369 — Safety Biomarker (SAF): Hyaluronic acid
Study 23095606 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 23095606 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8549083 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 21417594 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21417594 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18802361 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 17490567 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9771513 — Surrogate Endpoint (SUR): Blood pressure
Study 3341209 — Surrogate Endpoint (SUR): Blood pressure
Study 29857009 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 29857009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29857009 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 19297072 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17846552 — Surrogate Endpoint (SUR): Blood pressure
Study 10692276 — Surrogate Endpoint (SUR): Serum sodium
Study 9181154 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20202290 — Surrogate Endpoint (SUR): Blood pressure
Study 8636761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8636761 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1346121 — Surrogate Endpoint (SUR): Blood pressure
Study 20852176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15692120 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15692120 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24956324 — Surrogate Endpoint (SUR): Blood pressure
Study 16805922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10997396 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10997396 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 10997396 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 10997396 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10997396 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 10997396 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10997396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10997396 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 6689183 — Surrogate Endpoint (SUR): Blood pressure
Study 29579042 — Predictive Biomarker (PRD): ST8SIA5 mRNA
Genes: ST8SIA5; SIAT8E
Study 25049132 — Predictive Biomarker (PRD): GCG mRNA
Genes: GCG
Study 17345784 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17345784 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17345784 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30462806 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26687391 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26687391 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 26687391 — Predictive Biomarker (PRD): miR-25
Genes: MIR25
Study 26687391 — Predictive Biomarker (PRD): miR-145
Genes: MIR145
Study 26687391 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-210
Genes: MIR210
Study 20595158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20595158 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 20595158 — Safety Biomarker (SAF): Interleukin 12
Study 20595158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3303926 — Surrogate Endpoint (SUR): Serum creatinine
Study 21631599 — Surrogate Endpoint (SUR): Bone mineral density
Study 17157802 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 14962830 — Surrogate Endpoint (SUR): Blood pressure
Study 12361201 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9466515 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9466515 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9519356 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 10088798 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 2209315 — Surrogate Endpoint (SUR): Blood pressure
Study 28728956 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 26056125 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 22559159 — Surrogate Endpoint (SUR): Blood pressure
Study 19712037 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15894768 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12503776 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12503776 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9583201 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24764581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14584060 — Predictive Biomarker (PRD): Hormone receptor
Study 10915847 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 8261826 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8261826 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 3065739 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 3065739 — Predictive Biomarker (PRD): CLYBL mRNA
Genes: CLYBL; CLB
Study 27463071 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24001084 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 25174991 — Surrogate Endpoint (SUR): Bone mineral density
Study 19514614 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19514614 — Surrogate Endpoint (SUR): Blood pressure
Study 7889893 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 7889893 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30111467 — Surrogate Endpoint (SUR): Blood pressure
Study 22855730 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 11799303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2680475 — Surrogate Endpoint (SUR): Blood pressure
Study 23548422 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 31585826 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 28359513 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 19268776 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19268776 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 19268776 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 9623550 — Safety Biomarker (SAF): 51Cr-EDTA
Study 23973689 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23973689 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20234350 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 20234350 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 10338170 — Surrogate Endpoint (SUR): Blood pressure
Study 7795833 — Surrogate Endpoint (SUR): Blood pressure
Study 23574533 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study 17338998 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 30745885 — Surrogate Endpoint (SUR): Bone mineral density
Study 27316586 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22669847 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19728082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19728082 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 19728082 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16082323 — Surrogate Endpoint (SUR): Serum creatinine
Study 11922360 — Surrogate Endpoint (SUR): Blood pressure
Study 10516867 — Surrogate Endpoint (SUR): Blood pressure
Study 18629370 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12900341 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26650913 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22715372 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 20651475 — Surrogate Endpoint (SUR): Blood pressure
Study 23640589 — Surrogate Endpoint (SUR): Blood pressure
Study 9772612 — Surrogate Endpoint (SUR): Serum creatinine
Study 15148271 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 31324206 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16035398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 16035398 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 30753672 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 30753672 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 30753672 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30753672 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 23994369 — Surrogate Endpoint (SUR): Serum uric acid
Study 29688615 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29688615 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17434845 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2803403 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 26304941 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 23538664 — Surrogate Endpoint (SUR): Blood pressure
Study 23538664 — Surrogate Endpoint (SUR): Serum sodium
Study 20951830 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 6793298 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 6793298 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 6793298 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 16542370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12669261 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 2566286 — Surrogate Endpoint (SUR): Blood pressure
Study 21990511 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21990511 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 21990511 — Surrogate Endpoint (SUR): Blood pressure
Study 19893125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17950088 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 15096905 — Surrogate Endpoint (SUR): Blood pressure
Study 11966786 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 9474447 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 7699188 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17349882 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15292365 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 9560042 — Surrogate Endpoint (SUR): Blood pressure
Study 3622197 — Surrogate Endpoint (SUR): Serum creatinine
Study 3622197 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 27009295 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16204662 — Surrogate Endpoint (SUR): Blood pressure
Study 31557492 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31557492 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 18773960 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 18773960 — Surrogate Endpoint (SUR): Serum creatinine
Study 23439357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23439357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23439357 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23845297 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 20501622 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 20501622 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18707820 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 8800165 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 6365351 — Surrogate Endpoint (SUR): Blood pressure
Study 8129608 — Safety Biomarker (SAF): Cytochrome c
Study 29019364 — Surrogate Endpoint (SUR): Blood pressure
Study 21332563 — Surrogate Endpoint (SUR): Blood pressure
Study 17082474 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15554360 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9226484 — Surrogate Endpoint (SUR): Blood pressure
Study 18362489 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 16120545 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10195522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24687833 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24687833 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 24687833 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 14761073 — Surrogate Endpoint (SUR): Blood pressure
Study 15792677 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 15792677 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 10519944 — Predictive Biomarker (PRD): TMPRSS13 mRNA
Genes: TMPRSS13; MSP; TMPRSS11
Study 7202896 — Surrogate Endpoint (SUR): Blood pressure
Study 23565841 — Surrogate Endpoint (SUR): Blood pressure
Study 21150222 — Predictive Biomarker (PRD): Intact parathyroid hormone