TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8698446 — Surrogate Endpoint (SUR): Blood pressure
Study 24700342 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study 18724827 — Surrogate Endpoint (SUR): Blood pressure
Study 16622803 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 12670840 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 20708715 — Surrogate Endpoint (SUR): Blood pressure
Study 16782924 — Predictive Biomarker (PRD): RTL1 mRNA
Genes: RTL1; MAR1; MART1; PEG11
Study 16782924 — Predictive Biomarker (PRD): MAGEA3 mRNA
Genes: MAGEA3; MAGE3
Study 9534750 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9534750 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10999790 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10999790 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31601493 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 24742498 — Surrogate Endpoint (SUR): Blood pressure
Study 21614479 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 19580461 — Surrogate Endpoint (SUR): Bone mineral density
Study 19506174 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19506174 — Surrogate Endpoint (SUR): Blood pressure
Study 21402547 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21402547 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 10871909 — Surrogate Endpoint (SUR): Bone mineral density
Study 8508996 — Surrogate Endpoint (SUR): Blood pressure
Study 27602508 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 25341478 — Surrogate Endpoint (SUR): Blood pressure
Study 17289483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17289483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17289483 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12574871 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 12574871 — Surrogate Endpoint (SUR): Bone mineral density
Study 3781985 — Surrogate Endpoint (SUR): Blood pressure
Study 30238915 — Predictive Biomarker (PRD): NE
Study 23519822 — Surrogate Endpoint (SUR): Blood pressure
Study 20386016 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 12897739 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8855830 — Surrogate Endpoint (SUR): Blood pressure
Study 8855830 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19414584 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9134274 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9134274 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25889222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7810816 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2853765 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2853765 — Surrogate Endpoint (SUR): Blood pressure
Study 15642557 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 15642557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15642557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30599367 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16724678 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24293166 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 9169747 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9169747 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29328860 — Predictive Biomarker (PRD): Hormone receptor
Study 27206939 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25052061 — Predictive Biomarker (PRD): MEST mRNA
Genes: MEST; PEG1
Study 9715790 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 9715790 — Surrogate Endpoint (SUR): Blood pressure
Study 7866465 — Surrogate Endpoint (SUR): Blood pressure
Study 7866465 — Surrogate Endpoint (SUR): Bone mineral density
Study 30925951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30925951 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 30925951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25788492 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25788492 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23688546 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 17904221 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 17904221 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9653567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9653567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9989682 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 2183733 — Surrogate Endpoint (SUR): Blood pressure
Study 31468659 — Surrogate Endpoint (SUR): Serum creatinine
Study 26484767 — Surrogate Endpoint (SUR): Blood pressure
Study 23175769 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19047814 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 8478043 — Surrogate Endpoint (SUR): Blood pressure
Study 1831083 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 7066289 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30586691 — Surrogate Endpoint (SUR): Blood pressure
Study 17489898 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30987917 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 25698492 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25698492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11526203 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17443000 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17443000 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31461400 — Predictive Biomarker (PRD): CDON mRNA
Genes: CDON; CDO
Study 21314329 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21314329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14604059 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29767728 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 25252254 — Predictive Biomarker (PRD): NBN mRNA
Genes: NBN; NBS; NBS1; P95
Study 15747897 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24256097 — Surrogate Endpoint (SUR): Blood pressure
Study 14984435 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22563210 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 7589012 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7146823 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 7146823 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26508309 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 22131224 — Surrogate Endpoint (SUR): Blood pressure
Study 18419350 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 8665532 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 22331954 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16973657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15815820 — Surrogate Endpoint (SUR): Blood pressure
Study 11223695 — Surrogate Endpoint (SUR): Serum creatinine
Study 7896386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 3630961 — Surrogate Endpoint (SUR): Blood pressure
Study 26043884 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19190553 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 15313947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8935811 — Safety Biomarker (SAF): DRD2
Study 10331442 — Predictive Biomarker (PRD): CLTB mRNA
Genes: CLTB
Study 10331442 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21873710 — Surrogate Endpoint (SUR): Blood pressure
Study 18640686 — Surrogate Endpoint (SUR): Blood pressure
Study 10230950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10230950 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10230950 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31087200 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21658141 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 23167953 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21706269 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 21706269 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21706269 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8640163 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30297397 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26358120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22451451 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22451451 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19121416 — Surrogate Endpoint (SUR): Bone mineral density
Study 31977865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31977865 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31977865 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23921860 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 26252526 — Safety Biomarker (SAF): Interleukin 12
Study 26252526 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11479157 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 11479157 — Surrogate Endpoint (SUR): Serum creatinine
Study 11479157 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 11751721 — Surrogate Endpoint (SUR): Blood pressure
Study 3327654 — Surrogate Endpoint (SUR): Blood pressure
Study 30165438 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23996969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22330261 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 9638984 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 30951497 — Safety Biomarker (SAF): Hyaluronic acid
Study 26313133 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26313133 — Safety Biomarker (SAF): BDNF
Study 8757381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8757381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8757381 — Safety Biomarker (SAF): Interleukin 1
Study 8757381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1682907 — Surrogate Endpoint (SUR): Blood pressure
Study 6807681 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 27358067 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22990854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22990854 — Surrogate Endpoint (SUR): Plasma sitosterol and campesterol
Study 17201457 — Predictive Biomarker (PRD): SLC35A2 mRNA
Genes: SLC35A2; UGALT; UGT; UGTL
Study 17201457 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16263350 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31241992 — Surrogate Endpoint (SUR): Serum creatinine
Study 31241992 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31241362 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31241362 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28472976 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28472976 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 9375889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3929513 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 25763921 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study 23736807 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16395725 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16395725 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11564035 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 7817797 — Surrogate Endpoint (SUR): Bone mineral density
Study 25263372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19274909 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 30761523 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30761523 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23264537 — Predictive Biomarker (PRD): SLC16A4 mRNA
Genes: SLC16A4; MCT4; MCT5
Study 23264537 — Predictive Biomarker (PRD): MCTS1 mRNA
Genes: MCTS1; MCT1
Study 19035876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10225812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8876346 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 8876346 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 29498469 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 29498469 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26888258 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 7658599 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 791331 — Surrogate Endpoint (SUR): Blood pressure
Study 21982529 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14661817 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3884122 — Surrogate Endpoint (SUR): Blood pressure
Study 3884122 — Surrogate Endpoint (SUR): Serum potassium
Study 20033907 — Safety Biomarker (SAF): DRD2
Study 26383695 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 24126796 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21788373 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 15855970 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 11932564 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29978417 — Surrogate Endpoint (SUR): Blood pressure
Study 10636265 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10636265 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 10636265 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31433919 — Surrogate Endpoint (SUR): Blood pressure
Study 9422295 — Surrogate Endpoint (SUR): Blood pressure
Study 15911730 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15911730 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27164866 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 12058997 — Safety Biomarker (SAF): Urinary microalbumin
Study 9862248 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9862248 — Surrogate Endpoint (SUR): Blood pressure
Study 27027462 — Predictive Biomarker (PRD): KCNJ6 mRNA
Genes: KCNJ6; GIRK2; KATP2; KCNJ7
Study 27027462 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 22921680 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18503929 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 18503929 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30739911 — Predictive Biomarker (PRD): STK4 mRNA
Genes: STK4; KRS2; MST1
Study 24613543 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22384088 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 18251141 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15734253 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29046015 — Surrogate Endpoint (SUR): Blood pressure
Study 25929192 — Surrogate Endpoint (SUR): Bone mineral density
Study 16899830 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7841973 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7841973 — Surrogate Endpoint (SUR): Blood pressure
Study 3180489 — Surrogate Endpoint (SUR): Blood pressure
Study 18771605 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31753727 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27073205 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27073205 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12919710 — Surrogate Endpoint (SUR): Bone mineral density
Study 9004094 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24581948 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24581948 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15730052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10911770 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28276743 — Surrogate Endpoint (SUR): Blood pressure
Study 15369420 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15369420 — Surrogate Endpoint (SUR): Blood pressure
Study 15369420 — Surrogate Endpoint (SUR): Serum creatinine
Study 11514487 — Surrogate Endpoint (SUR): Blood pressure
Study 9344704 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9344704 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 9344704 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9344704 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9344704 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9344704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22721873 — Surrogate Endpoint (SUR): Blood pressure
Study 11060814 — Predictive Biomarker (PRD): GCSAM mRNA
Genes: GCSAM; GAL; GCET2
Study 1484852 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25168098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19293693 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22404431 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22404431 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 20515418 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18541083 — Surrogate Endpoint (SUR): Bacterial count
Study 10486670 — Surrogate Endpoint (SUR): Blood pressure
Study 25670364 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25670364 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25670364 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23033926 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23033926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23033926 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25765965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21784351 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18027048 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 18027048 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18027048 — Surrogate Endpoint (SUR): Blood pressure
Study 7991068 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 17124720 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 31971279 — Surrogate Endpoint (SUR): Serum creatinine
Study 31971279 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30585257 — Safety Biomarker (SAF): UGT1A1
Genes: UGT1A
Study 25980699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22068444 — Surrogate Endpoint (SUR): Blood pressure
Study 7777109 — Surrogate Endpoint (SUR): Bone mineral density
Study 2131899 — Surrogate Endpoint (SUR): Blood pressure