TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29843811 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 20090776 — Surrogate Endpoint (SUR): Blood pressure
Study 16187171 — Surrogate Endpoint (SUR): Serum creatinine
Study 16187171 — Surrogate Endpoint (SUR): Serum sodium
Study 17563999 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29486879 — Surrogate Endpoint (SUR): Blood pressure
Study 26678437 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 20450412 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9299668 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23013946 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 21661459 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 457522 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10480624 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 1753612 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12196868 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31012860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31012860 — Surrogate Endpoint (SUR): Blood pressure
Study 21079937 — Surrogate Endpoint (SUR): Blood pressure
Study 8267110 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 12097595 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12097595 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8029608 — Surrogate Endpoint (SUR): Serum sodium
Study 31509228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25043606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24284154 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19959686 — Predictive Biomarker (PRD): OGG1 mRNA
Genes: OGG1; MMH; MUTM; OGH1
Study 19959686 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19959686 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 16903842 — Surrogate Endpoint (SUR): Blood pressure
Study 15128017 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27853809 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26033407 — Surrogate Endpoint (SUR): Blood pressure
Study 23553596 — Predictive Biomarker (PRD): Liver iron
Study 21464362 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 21464362 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 25763936 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 9745864 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 27232649 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25306266 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25306266 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16623675 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16623675 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12623762 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12623762 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8744579 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 8744579 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6131800 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 24755125 — Surrogate Endpoint (SUR): Blood pressure
Study 18086052 — Safety Biomarker (SAF): Hyaluronic acid
Study 15331687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15331687 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 15331687 — Safety Biomarker (SAF): Interleukin 1
Study 12577350 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 12577350 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 12577350 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28581821 — Surrogate Endpoint (SUR): Blood pressure
Study 14607447 — Surrogate Endpoint (SUR): Blood pressure
Study 10948076 — Predictive Biomarker (PRD): HSD11B2 mRNA
Genes: HSD11B2; HSD11K; SDR9C3
Study 1616866 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29357482 — Predictive Biomarker (PRD): LAMP2 mRNA
Genes: LAMP2
Study 29357482 — Predictive Biomarker (PRD): MYF6 mRNA
Genes: MYF6; BHLHC4; MRF4
Study 29357482 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 20418083 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11041320 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9048274 — Surrogate Endpoint (SUR): Blood pressure
Study 3518770 — Surrogate Endpoint (SUR): Blood pressure
Study 27022224 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24529502 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 12235445 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29286940 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 26345100 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17298349 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11069821 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3751735 — Surrogate Endpoint (SUR): Blood pressure
Study 23723326 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22950600 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 22950600 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16139336 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 12637462 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 30715132 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 28498655 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 25828621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25828621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23950599 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 20624784 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9718095 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 9718095 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 9718095 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 25411159 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15182277 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 15182277 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 15182277 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15182277 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24064347 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 11675948 — Surrogate Endpoint (SUR): Blood pressure
Study 21804463 — Surrogate Endpoint (SUR): Bone mineral density
Study 15297775 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15297775 — Safety Biomarker (SAF): 51Cr-EDTA
Study 6181560 — Safety Biomarker (SAF): 51Cr-EDTA
Study 15011418 — Surrogate Endpoint (SUR): Blood pressure
Study 9536857 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9536857 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9536857 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3197370 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 3197370 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29016943 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 24171779 — Surrogate Endpoint (SUR): Blood pressure
Study 10929918 — Surrogate Endpoint (SUR): Blood pressure
Study 10929918 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23957382 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17161051 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17161051 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 8718436 — Surrogate Endpoint (SUR): Blood pressure
Study 12756509 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31309239 — Surrogate Endpoint (SUR): Bone mineral density
Study 29055242 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 23895296 — Predictive Biomarker (PRD): NDRG1 mRNA
Genes: NDRG1; CAP43; DRG1; RTP
Study 23895296 — Surrogate Endpoint (SUR): Serum creatinine
Study 21320198 — Surrogate Endpoint (SUR): Blood pressure
Study 31150084 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 31150084 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23312343 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15915004 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15915004 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 577445 — Surrogate Endpoint (SUR): Blood pressure
Study 23397863 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11895160 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8535553 — Surrogate Endpoint (SUR): Blood pressure
Study 23973636 — Surrogate Endpoint (SUR): Blood pressure
Study 12093831 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9560053 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28370178 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 26438237 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26438237 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 26438237 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 19808351 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17584566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15386625 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 8026287 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19954496 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 2869676 — Surrogate Endpoint (SUR): Blood pressure
Study 27825738 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 18803955 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 11974560 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28195933 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17426157 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 17426157 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 17426157 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 9463638 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8314135 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28235621 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 25963985 — Predictive Biomarker (PRD): SLC38A3 mRNA
Genes: SLC38A3; G17; NAT1; SN1; SNAT3
Study 25963985 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 11713130 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 9385910 — Surrogate Endpoint (SUR): Blood pressure
Study 29229305 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 12637791 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 10434822 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 2191769 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 27209164 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27209164 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27209164 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24039147 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 31727154 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 26876425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22413452 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22605570 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22605570 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7493434 — Surrogate Endpoint (SUR): Blood pressure
Study 17766739 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11489708 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 1493935 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30859741 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24268212 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22284315 — Surrogate Endpoint (SUR): Blood pressure
Study 2572036 — Surrogate Endpoint (SUR): Blood pressure
Study 319271 — Surrogate Endpoint (SUR): Blood pressure
Study 319271 — Surrogate Endpoint (SUR): Serum uric acid
Study 319271 — Surrogate Endpoint (SUR): Serum potassium
Study 319271 — Surrogate Endpoint (SUR): Serum creatinine
Study 31843335 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25326135 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 17159017 — Surrogate Endpoint (SUR): Bone mineral density
Study 11127213 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11127213 — Surrogate Endpoint (SUR): Bone mineral density
Study 9192993 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9192993 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7948351 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29086103 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 18537189 — Monitoring Biomarker (MOI): HBV DNA
Study 12860920 — Surrogate Endpoint (SUR): Blood pressure
Study 10382913 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 2252879 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 19482902 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 30305151 — Safety Biomarker (SAF): BDNF
Study 21415358 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 6374280 — Surrogate Endpoint (SUR): Blood pressure
Study 29452178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25390695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25390695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25390695 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23075178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23075178 — Safety Biomarker (SAF): Interleukin 12
Study 20156909 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 17360171 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16352931 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7666098 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 19602903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19602903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11115036 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 3490803 — Surrogate Endpoint (SUR): Blood pressure
Study 29248753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29248753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10406826 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 22991208 — Predictive Biomarker (PRD): PDE1A mRNA
Genes: PDE1A
Study 22991208 — Predictive Biomarker (PRD): MTARC1 mRNA
Genes: MTARC1; MARC1; MOSC1
Study 22991208 — Predictive Biomarker (PRD): CRIP3 mRNA
Genes: CRIP3; CRP3
Study 15757423 — Surrogate Endpoint (SUR): Blood pressure
Study 1847721 — Surrogate Endpoint (SUR): Serum creatinine
Study 27372462 — Surrogate Endpoint (SUR): Blood pressure
Study 21855289 — Surrogate Endpoint (SUR): Blood pressure
Study 9665214 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24034570 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24034570 — Predictive Biomarker (PRD): FCMR mRNA
Genes: FCMR; FAIM3; TOSO
Study 9700993 — Surrogate Endpoint (SUR): Blood pressure
Study 16713435 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7962344 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7962344 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25930719 — Surrogate Endpoint (SUR): Bone mineral density
Study 21865084 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 1424650 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26964554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17591032 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17591032 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15501922 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15501922 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 9469359 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 21385602 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21385602 — Safety Biomarker (SAF): BDNF
Study 19472440 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 18043308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18043308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18043308 — Surrogate Endpoint (SUR): Blood pressure
Study 9168215 — Surrogate Endpoint (SUR): Blood pressure
Study 17301564 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15064315 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15064315 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2676558 — Surrogate Endpoint (SUR): Blood pressure
Study 31515173 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 23574727 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23574727 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23574727 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23574727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23574727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23574727 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 19845035 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 16706691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14995150 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17215845 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 17215845 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17215845 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 15164249 — Surrogate Endpoint (SUR): Serum creatinine
Study 29479906 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11087700 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 3512970 — Predictive Biomarker (PRD): TIMM8A mRNA
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 31023842 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 20192619 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 18184544 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18184544 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8136110 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8136110 — Surrogate Endpoint (SUR): Blood pressure
Study 2644532 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27768831 — Surrogate Endpoint (SUR): Bone mineral density
Study 21788632 — Surrogate Endpoint (SUR): Blood pressure
Study 15287932 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15287932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10924631 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 10924631 — Surrogate Endpoint (SUR): Blood pressure
Study 6360414 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16807272 — Surrogate Endpoint (SUR): Blood pressure
Study 16807272 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16807272 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10340921 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 1793154 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 17310957 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17310957 — Surrogate Endpoint (SUR): Serum creatinine
Study 20051618 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 11558858 — Surrogate Endpoint (SUR): Blood pressure
Study 9755543 — Surrogate Endpoint (SUR): Blood pressure
Study 9755543 — Surrogate Endpoint (SUR): Serum potassium
Study 21597220 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 10873076 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20868279 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18778120 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1