TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16899485 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 10663618 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 38965 — Surrogate Endpoint (SUR): Blood pressure
Study 28052915 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 19491860 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 22417212 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 22417212 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 1703920 — Surrogate Endpoint (SUR): Blood pressure
Study 31745073 — Predictive Biomarker (PRD): ADH1B mRNA
Genes: ADH1B; ADH2
Study 28671332 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 28671332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25702819 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 23419134 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21953407 — Surrogate Endpoint (SUR): Blood pressure
Study 30128934 — Safety Biomarker (SAF): Hyaluronic acid
Study 17047171 — Surrogate Endpoint (SUR): Bone mineral density
Study 17047171 — Surrogate Endpoint (SUR): Serum calcium
Study 14609147 — Surrogate Endpoint (SUR): Blood pressure
Study 20200284 — Surrogate Endpoint (SUR): Blood pressure
Study 18028245 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 10423646 — Surrogate Endpoint (SUR): Serum potassium
Study 16733299 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16733299 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16733299 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11041441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9377121 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3517554 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20973322 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 20837371 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1436339 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28268084 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21346060 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 21346060 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21346060 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9144030 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8188397 — Surrogate Endpoint (SUR): Blood pressure
Study 8188397 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 8877678 — Surrogate Endpoint (SUR): Serum testosterone
Study 22927772 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 22927772 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 30212930 — Predictive Biomarker (PRD): MAPKAPK3 mRNA
Genes: MAPKAPK3
Study 30212930 — Predictive Biomarker (PRD): ARRB2 mRNA
Genes: ARRB2; ARB2; ARR2
Study 30212930 — Predictive Biomarker (PRD): SLC19A1 mRNA
Genes: SLC19A1; FLOT1; RFC1
Study 30212930 — Predictive Biomarker (PRD): PRKCD mRNA
Genes: PRKCD; PKCD
Study 30212930 — Predictive Biomarker (PRD): RHOG mRNA
Genes: RHOG; ARHG
Study 30212930 — Predictive Biomarker (PRD): PTPN6 mRNA
Genes: PTPN6; HCP; PTP1C
Study 30212930 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 30212930 — Predictive Biomarker (PRD): CNPY3 mRNA
Genes: CNPY3; CTG4A; ERDA5; PRAT4A; TNRC5; HSPC084; UNQ1934/PRO4409
Study 30212930 — Predictive Biomarker (PRD): PYGL mRNA
Genes: PYGL
Study 30212930 — Predictive Biomarker (PRD): ARNT mRNA
Genes: ARNT; BHLHE2
Study 30212930 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 20478035 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12909392 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 1858191 — Surrogate Endpoint (SUR): Blood pressure
Study 17359515 — Surrogate Endpoint (SUR): Blood pressure
Study 12040967 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12040967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1699337 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1699337 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25748830 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17520465 — Predictive Biomarker (PRD): CPOX mRNA
Genes: CPOX; CPO; CPX
Study 10221357 — Surrogate Endpoint (SUR): Blood pressure
Study 14615471 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 1541787 — Surrogate Endpoint (SUR): Serum sodium
Study 1541787 — Surrogate Endpoint (SUR): Serum potassium
Study 3872835 — Surrogate Endpoint (SUR): Blood pressure
Study 28961380 — Predictive Biomarker (PRD): ALPP mRNA
Genes: ALPP; PLAP
Study 21492764 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21492764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8889317 — Surrogate Endpoint (SUR): Blood pressure
Study 1824585 — Surrogate Endpoint (SUR): Blood pressure
Study 6407438 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 1832344 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1832344 — Surrogate Endpoint (SUR): Blood pressure
Study 20658820 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 15557136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1686784 — Surrogate Endpoint (SUR): Blood pressure
Study 29882087 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 29882087 — Surrogate Endpoint (SUR): Blood pressure
Study 23075703 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20574412 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9932566 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31298337 — Predictive Biomarker (PRD): SOX11 mRNA
Genes: SOX11
Study 31298337 — Predictive Biomarker (PRD): miR-31
Genes: MIR31
Study 8063651 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 11529248 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11529248 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17766699 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 10634921 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 10634921 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 30795731 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 25564476 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 20939064 — Surrogate Endpoint (SUR): Bone mineral density
Study 16710253 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16710253 — Surrogate Endpoint (SUR): Blood pressure
Study 29504258 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 29504258 — Surrogate Endpoint (SUR): Blood pressure
Study 21092504 — Surrogate Endpoint (SUR): Serum creatinine
Study 10543576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22100966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ADAM11 mRNA
Genes: ADAM11; MDC
Study 22100966 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 16298235 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 10757578 — Surrogate Endpoint (SUR): Blood pressure
Study 19954777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19954777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19954777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8996129 — Surrogate Endpoint (SUR): Blood pressure
Study 27436668 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22677927 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22677927 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22677927 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 18262758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18262758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16874160 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 16874160 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27412942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27412942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27412942 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 27412942 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27412942 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17565578 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 17565578 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12466345 — Surrogate Endpoint (SUR): Blood pressure
Study 8533868 — Surrogate Endpoint (SUR): Blood pressure
Study 2148278 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31117100 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 1824654 — Surrogate Endpoint (SUR): Blood pressure
Study 22168752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 22168752 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 22168752 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20156896 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 11840224 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11840224 — Surrogate Endpoint (SUR): Blood pressure
Study 30473033 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 26681677 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11512193 — Surrogate Endpoint (SUR): Probing pocket depth
Study 318493 — Surrogate Endpoint (SUR): Blood pressure
Study 19214120 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1915428 — Surrogate Endpoint (SUR): Blood pressure
Study 31409515 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 31409515 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study 23359232 — Predictive Biomarker (PRD): SPTB mRNA
Genes: SPTB; SPTB1
Study 21546436 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 15554358 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 7965282 — Surrogate Endpoint (SUR): Blood pressure
Study 29149349 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 18277180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18277180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18277180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18277180 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 1348916 — Surrogate Endpoint (SUR): Blood pressure
Study 21552672 — Surrogate Endpoint (SUR): Blood pressure
Study 11704374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22852059 — Surrogate Endpoint (SUR): Blood pressure
Study 29435729 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 8875971 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31336654 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 31336654 — Predictive Biomarker (PRD): SLC6A7 mRNA
Genes: SLC6A7; PROT
Study 31336654 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 12434648 — Surrogate Endpoint (SUR): Blood pressure
Study 9884251 — Surrogate Endpoint (SUR): Blood pressure
Study 9884251 — Surrogate Endpoint (SUR): Serum creatinine
Study 7640495 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 7640495 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 19494484 — Surrogate Endpoint (SUR): Serum creatinine
Study 18037816 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 8131770 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25336745 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 18606901 — Surrogate Endpoint (SUR): Blood pressure
Study 18606901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1352050 — Safety Biomarker (SAF): DRD2
Study 3540025 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29126396 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 29126396 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 24157432 — Surrogate Endpoint (SUR): Blood pressure
Study 18510068 — Surrogate Endpoint (SUR): Blood pressure
Study 16513672 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 16513672 — Surrogate Endpoint (SUR): Blood pressure
Study 11983727 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9806692 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22475819 — Surrogate Endpoint (SUR): Serum creatinine
Study 2044648 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29460509 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 20042191 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 20042191 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 20042191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16043121 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 28131045 — Predictive Biomarker (PRD): TRAF3 mRNA
Genes: TRAF3; CAP-1; CRAF1; TRAFAMN
Study 28131045 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 28131045 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28131045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24961021 — Surrogate Endpoint (SUR): Blood pressure
Study 20074751 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20074751 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3306508 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 12840859 — Predictive Biomarker (PRD): CLYBL mRNA
Genes: CLYBL; CLB
Study 12840859 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 30794304 — Surrogate Endpoint (SUR): Blood pressure
Study 28130552 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 28130552 — Predictive Biomarker (PRD): MAPK1 mRNA
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study 28130552 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 28130552 — Predictive Biomarker (PRD): RUNX2 mRNA
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 28130552 — Predictive Biomarker (PRD): MAPK7 mRNA
Genes: MAPK7; BMK1; ERK5; PRKM7
Study 28130552 — Predictive Biomarker (PRD): NFKB1 mRNA
Genes: NFKB1
Study 28130552 — Predictive Biomarker (PRD): ITGB1 mRNA
Genes: ITGB1; FNRB; MDF2; MSK12
Study 28130552 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 28130552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 28130552 — Surrogate Endpoint (SUR): Bone mineral density
Study 2205379 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19158369 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 26656981 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 8223165 — Surrogate Endpoint (SUR): Blood pressure
Study 24962666 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9877147 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8560416 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8560416 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31862312 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31862312 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 31862312 — Surrogate Endpoint (SUR): Blood pressure
Study 30690191 — Surrogate Endpoint (SUR): Serum testosterone
Study 26644202 — Predictive Biomarker (PRD): LINGO2 mRNA
Genes: LINGO2; LERN3; LRRN6C; UNQ9234/PRO31993
Study 26644202 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 26644202 — Predictive Biomarker (PRD): DUSP26 mRNA
Genes: DUSP26; DUSP24; LDP4; MKP8; NATA1; SKRP3
Study 26644202 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23459854 — Surrogate Endpoint (SUR): Blood pressure
Study 19394034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11550168 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 11550168 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 27627981 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17711908 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 7968874 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7968874 — Surrogate Endpoint (SUR): Blood pressure
Study 27770114 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27770114 — Surrogate Endpoint (SUR): Blood pressure
Study 22116817 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 20858400 — Surrogate Endpoint (SUR): Blood pressure
Study 11253476 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 30904178 — Surrogate Endpoint (SUR): Blood pressure
Study 30904178 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1358118 — Surrogate Endpoint (SUR): Blood pressure
Study 31465088 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31465088 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study 31465088 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23122916 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 19351753 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 19351753 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 19351753 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30678199 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 27127102 — Surrogate Endpoint (SUR): Blood pressure
Study 22904136 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20399059 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20399059 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15800995 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15800995 — Monitoring Biomarker (MOI): HBV DNA
Study 12876093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12876093 — Surrogate Endpoint (SUR): Blood pressure
Study 12876093 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8681494 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2071560 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 26138292 — Predictive Biomarker (PRD): CXCR5 mRNA
Genes: CXCR5; BLR1; MDR15
Study 26138292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9177364 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8463521 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 29864418 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 29864418 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 20049951 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 18720362 — Surrogate Endpoint (SUR): Serum calcium
Study 18720362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16253102 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 12381079 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20577130 — Surrogate Endpoint (SUR): Blood pressure
Study 17434094 — Surrogate Endpoint (SUR): Blood pressure
Study 16315822 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 19925464 — Surrogate Endpoint (SUR): Serum creatinine
Study 17884451 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17884451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17884451 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31340979 — Predictive Biomarker (PRD): PLA2R1 mRNA
Genes: PLA2R1; CLEC13C
Study 31340979 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 19884620 — Surrogate Endpoint (SUR): Blood pressure
Study 15279619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15279619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11157183 — Surrogate Endpoint (SUR): Blood pressure
Study 25573751 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 22244715 — Surrogate Endpoint (SUR): Blood pressure
Study 1443704 — Surrogate Endpoint (SUR): Blood pressure
Study 31992758 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31992758 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31992758 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23636469 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE