TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22408123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22408123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22408123 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 22408123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22408123 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 26116264 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8664529 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1518670 — Surrogate Endpoint (SUR): Blood pressure
Study 28687937 — Surrogate Endpoint (SUR): Blood pressure
Study 28687937 — Surrogate Endpoint (SUR): Serum uric acid
Study 25448925 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23643425 — Surrogate Endpoint (SUR): Blood pressure
Study 19555395 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 19555395 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19555395 — Surrogate Endpoint (SUR): Blood pressure
Study 19555395 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9773262 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8005128 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8005128 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31911249 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28171710 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31680085 — Surrogate Endpoint (SUR): Blood pressure
Study 24164872 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 2075773 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6942648 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6942648 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30787601 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30787601 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 25217039 — Surrogate Endpoint (SUR): Blood pressure
Study 7019706 — Surrogate Endpoint (SUR): Blood pressure
Study 22777113 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 22777113 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 22777113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22777113 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 17927497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15837438 — Surrogate Endpoint (SUR): Blood pressure
Study 8180354 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8180354 — Safety Biomarker (SAF): Interleukin 1
Study 26939898 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 8382104 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28712152 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 23816022 — Surrogate Endpoint (SUR): Blood pressure
Study 16936533 — Surrogate Endpoint (SUR): Blood pressure
Study 1651610 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 6321376 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6321376 — Surrogate Endpoint (SUR): Blood pressure
Study 19922681 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17257428 — Surrogate Endpoint (SUR): Blood pressure
Study 15508665 — Surrogate Endpoint (SUR): Blood pressure
Study 8591371 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24052987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24052987 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24052987 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9300248 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 17563335 — Surrogate Endpoint (SUR): Serum creatinine
Study 21427147 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 15464773 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12792150 — Surrogate Endpoint (SUR): Bone mineral density
Study 10383596 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8707338 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 8707338 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8707338 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 8707338 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8707338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8707338 — Safety Biomarker (SAF): Human leucocyte antigen
Study 31340801 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 24938580 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 22813436 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22813436 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17602080 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 9101305 — Surrogate Endpoint (SUR): Blood pressure
Study 12006419 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22068866 — Surrogate Endpoint (SUR): Blood pressure
Study 20663203 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20663203 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12021225 — Surrogate Endpoint (SUR): Serum creatinine
Study 28257169 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28257169 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23868188 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19622617 — Surrogate Endpoint (SUR): Blood pressure
Study 16963350 — Surrogate Endpoint (SUR): Blood pressure
Study 10469292 — Surrogate Endpoint (SUR): Bone mineral density
Study 8834129 — Surrogate Endpoint (SUR): Blood pressure
Study 18058343 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 28974568 — Surrogate Endpoint (SUR): Blood pressure
Study 23880908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23880908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23880908 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31248461 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 31248461 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24977698 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21730307 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12117049 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7539633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7539633 — Safety Biomarker (SAF): Interleukin 1
Study 7539633 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7539633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25446057 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25446057 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27246689 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 24525158 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20579957 — Predictive Biomarker (PRD): SPTB mRNA
Genes: SPTB; SPTB1
Study 15814873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12215585 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12215585 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8704079 — Surrogate Endpoint (SUR): Blood pressure
Study 23909911 — Surrogate Endpoint (SUR): Blood pressure
Study 17116057 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 29316186 — Surrogate Endpoint (SUR): Blood pressure
Study 18259973 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16293781 — Surrogate Endpoint (SUR): Blood pressure
Study 16293781 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16293781 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11891095 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 30101910 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 20177349 — Surrogate Endpoint (SUR): Bone mineral density
Study 15764767 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10603631 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 22192672 — Surrogate Endpoint (SUR): Blood pressure
Study 9730795 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3154631 — Surrogate Endpoint (SUR): Blood pressure
Study 168650 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16957425 — Surrogate Endpoint (SUR): Blood pressure
Study 27896908 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 27896908 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 27896908 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27896908 — Surrogate Endpoint (SUR): Serum calcium
Study 17512160 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17512160 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 17512160 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 8961069 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8961069 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8961069 — Surrogate Endpoint (SUR): Blood pressure
Study 31712971 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25018015 — Predictive Biomarker (PRD): LTA4H mRNA
Genes: LTA4H; LTA4
Study 21079217 — Surrogate Endpoint (SUR): Bone mineral density
Study 21079217 — Surrogate Endpoint (SUR): Serum testosterone
Study 21079217 — Surrogate Endpoint (SUR): Serum creatinine
Study 17081356 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17081356 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 22155702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19940276 — Predictive Biomarker (PRD): EPHX2 mRNA
Genes: EPHX2
Study 12537671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10725769 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 26618456 — Safety Biomarker (SAF): Hyaluronic acid
Study 1302160 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25891210 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 17972053 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 17972053 — Predictive Biomarker (PRD): GNB3
Study 12475841 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28121710 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7926290 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 28842574 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 28842574 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 21119031 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15016021 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12542598 — Surrogate Endpoint (SUR): Serum creatinine
Study 8808110 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1361175 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1361175 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31170994 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 31170994 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 19297314 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8466068 — Surrogate Endpoint (SUR): Serum potassium
Study 21424698 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17572323 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 17572323 — Surrogate Endpoint (SUR): Blood pressure
Study 12951862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19324974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19324974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10214011 — Surrogate Endpoint (SUR): Blood pressure
Study 31782032 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25985446 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 31577070 — Safety Biomarker (SAF): Hyaluronic acid
Study 23146788 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DMRT1 mRNA
Genes: DMRT1; DMT1
Study 17918321 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12018633 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 23739686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23739686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14989442 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11228294 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 2468049 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29271486 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 26888806 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26888806 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23963331 — Safety Biomarker (SAF): Interleukin 1
Study 18326136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11712430 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 11712430 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11712430 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 30168626 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 27194023 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11341495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11341495 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11341495 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11341495 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 412995 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27958765 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 22498181 — Surrogate Endpoint (SUR): Blood pressure
Study 6996793 — Surrogate Endpoint (SUR): Blood pressure
Study 22463614 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11984215 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11984215 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23384300 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20938439 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 20938439 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20938439 — Surrogate Endpoint (SUR): Blood pressure
Study 16595221 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12883329 — Surrogate Endpoint (SUR): Blood pressure
Study 9273524 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6518665 — Surrogate Endpoint (SUR): Blood pressure
Study 23150144 — Surrogate Endpoint (SUR): Bone mineral density
Study 21496415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11516093 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8381931 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 28949012 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 24129358 — Surrogate Endpoint (SUR): Blood pressure
Study 23878319 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 20034487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14757967 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 11990103 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11990103 — Surrogate Endpoint (SUR): Blood pressure
Study 29753693 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 18725648 — Predictive Biomarker (PRD): Hormone receptor
Study 18725648 — Surrogate Endpoint (SUR): Bone mineral density
Study 15953803 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28033302 — Surrogate Endpoint (SUR): Blood pressure
Study 24885942 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24885942 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 12091047 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8594118 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 20586601 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20586601 — Surrogate Endpoint (SUR): Blood pressure
Study 18236139 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 18236139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 31227014 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28948979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28948979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24378958 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 24378958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7109988 — Surrogate Endpoint (SUR): Blood pressure
Study 27460638 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27460638 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17981885 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 8729588 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8729588 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25582578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17242633 — Surrogate Endpoint (SUR): Bone mineral density
Study 14739793 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 335912 — Surrogate Endpoint (SUR): Blood pressure
Study 24841333 — Surrogate Endpoint (SUR): Blood pressure
Study 11093505 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22257576 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 31190476 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 28968759 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18986859 — Safety Biomarker (SAF): Hyaluronic acid
Study 11694687 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9134635 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9134635 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25612882 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15666380 — Surrogate Endpoint (SUR): Blood pressure
Study 8948268 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 1766495 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30928279 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 30928279 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25935101 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25935101 — Surrogate Endpoint (SUR): Blood pressure
Study 18201582 — Surrogate Endpoint (SUR): Blood pressure
Study 11115423 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9450174 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9450174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24285128 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24285128 — Surrogate Endpoint (SUR): Serum creatinine
Study 24285128 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 14596355 — Surrogate Endpoint (SUR): Blood pressure
Study 9065092 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31127500 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 31127500 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31127500 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31127500 — Predictive Biomarker (PRD): Hormone receptor
Study 31127500 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17197840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9727072 — Surrogate Endpoint (SUR): Bone mineral density
Study 7953225 — Surrogate Endpoint (SUR): Bone mineral density
Study 28638000 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28638000 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein