TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8920850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8920850 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 1864205 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17394970 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 11812877 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 16045370 — Surrogate Endpoint (SUR): Blood pressure
Study 12390568 — Predictive Biomarker (PRD): PTGDS mRNA
Genes: PTGDS; PDS
Study 29474558 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27486164 — Surrogate Endpoint (SUR): Blood pressure
Study 22321061 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22321061 — Predictive Biomarker (PRD): Hormone receptor
Study 17559747 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22781634 — Surrogate Endpoint (SUR): Blood pressure
Study 20820146 — Surrogate Endpoint (SUR): Blood pressure
Study 20820146 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16466178 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 18046186 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18046186 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 18046186 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 16127757 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 16127757 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 12403023 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31451361 — Surrogate Endpoint (SUR): Blood pressure
Study 15243283 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 15243283 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 15243283 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31480482 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23880183 — Surrogate Endpoint (SUR): Blood pressure
Study 20368220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11473862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7988349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22643242 — Predictive Biomarker (PRD): SLC6A7 mRNA
Genes: SLC6A7; PROT
Study 30566712 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 27491822 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 12614536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6956376 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16549466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2129437 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 339084 — Surrogate Endpoint (SUR): Blood pressure
Study 29504369 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 17674351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6986746 — Surrogate Endpoint (SUR): Blood pressure
Study 24502951 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19358929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31358408 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31358408 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27916620 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 22872005 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30045425 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27487142 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 27487142 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16410446 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28929443 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 28929443 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 28929443 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28929443 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 28929443 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 28448779 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28448779 — Surrogate Endpoint (SUR): Blood pressure
Study 28448779 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28448779 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18547178 — Safety Biomarker (SAF): Hyaluronic acid
Study 12634887 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 1311653 — Surrogate Endpoint (SUR): Blood pressure
Study 16202722 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10078888 — Surrogate Endpoint (SUR): Blood pressure
Study 24655552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31207115 — Safety Biomarker (SAF): Hyaluronic acid
Study 9626153 — Surrogate Endpoint (SUR): Bone mineral density
Study 9626153 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 3429061 — Surrogate Endpoint (SUR): Blood pressure
Study 28962596 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 30426921 — Predictive Biomarker (PRD): PKD2L1 mRNA
Genes: PKD2L1; PKD2L; PKDL; TRPP3
Study 28730841 — Surrogate Endpoint (SUR): Blood pressure
Study 17008536 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10457868 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 17209666 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17209666 — Surrogate Endpoint (SUR): Blood pressure
Study 26043564 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 8347733 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28606422 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 24733770 — Surrogate Endpoint (SUR): Blood pressure
Study 24733770 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20064578 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30600137 — Surrogate Endpoint (SUR): Blood pressure
Study 30600137 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30600137 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21645196 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21645196 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12612196 — Surrogate Endpoint (SUR): Blood pressure
Study 10720861 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 19843485 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 27692565 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27692565 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19484969 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19484969 — Surrogate Endpoint (SUR): Blood pressure
Study 27921201 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 24596968 — Surrogate Endpoint (SUR): Blood pressure
Study 24520741 — Surrogate Endpoint (SUR): Blood pressure
Study 12124548 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7605950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2132179 — Surrogate Endpoint (SUR): Blood pressure
Study 28093243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28093243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28093243 — Surrogate Endpoint (SUR): Serum creatinine
Study 19857626 — Surrogate Endpoint (SUR): Blood pressure
Study 7875151 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26847114 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20930611 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20930611 — Safety Biomarker (SAF): Fibroblast growth factor 1
Genes: FGF1
Study 6345378 — Surrogate Endpoint (SUR): Blood pressure
Study 21060033 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 17984242 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 7692934 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25805886 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25805886 — Safety Biomarker (SAF): BDNF
Study 19148579 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28086201 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28086201 — Surrogate Endpoint (SUR): Blood pressure
Study 26235803 — Surrogate Endpoint (SUR): Total kidney volume
Study 23333929 — Surrogate Endpoint (SUR): Pathological complete response
Study 8796406 — Surrogate Endpoint (SUR): Blood pressure
Study 1732342 — Surrogate Endpoint (SUR): Serum creatinine
Study 6433737 — Surrogate Endpoint (SUR): Blood pressure
Study 25073879 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 21959024 — Monitoring Biomarker (MOI): Procalcitonin
Study 14671165 — Surrogate Endpoint (SUR): Bone mineral density
Study 14671165 — Surrogate Endpoint (SUR): Serum testosterone
Study 18089340 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 18089340 — Surrogate Endpoint (SUR): Blood pressure
Study 18089340 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 9600500 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 7128568 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 7128568 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21177724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18817894 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 14561987 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26915823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26915823 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26915823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26915823 — Safety Biomarker (SAF): BDNF
Study 22939642 — Safety Biomarker (SAF): Hyaluronic acid
Study 17460334 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17460334 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28359325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16467702 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9385881 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 30002098 — Surrogate Endpoint (SUR): Blood pressure
Study 27189162 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22565102 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11912261 — Surrogate Endpoint (SUR): Serum calcium
Study 21760515 — Surrogate Endpoint (SUR): Blood pressure
Study 9189212 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1415066 — Surrogate Endpoint (SUR): Serum calcium
Study 22488284 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 22488284 — Surrogate Endpoint (SUR): Blood pressure
Study 12624612 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12624612 — Surrogate Endpoint (SUR): Blood pressure
Study 8229544 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 12934465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3511692 — Surrogate Endpoint (SUR): Blood pressure
Study 22591021 — Surrogate Endpoint (SUR): Blood pressure
Study 18810400 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 12212256 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 8438616 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 21676280 — Safety Biomarker (SAF): Reactive oxygen species
Study 9702935 — Surrogate Endpoint (SUR): Blood pressure
Study 2690065 — Surrogate Endpoint (SUR): Blood pressure
Study 31079082 — Surrogate Endpoint (SUR): Blood pressure
Study 11533345 — Surrogate Endpoint (SUR): Blood pressure
Study 27449771 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 27449771 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 27449771 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 27449771 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 25856933 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 25856933 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22286314 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18327367 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18327367 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12441905 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10364642 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25436841 — Predictive Biomarker (PRD): GRIK1 mRNA
Genes: GRIK1; GLUR5
Study 15946418 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 22170375 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22170375 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22170375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2179277 — Surrogate Endpoint (SUR): Blood pressure
Study 161758 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 25833230 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 25833230 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 11895066 — Surrogate Endpoint (SUR): Bone mineral density
Study 2716439 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 2716439 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 27677161 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8494011 — Surrogate Endpoint (SUR): Blood pressure
Study 11293560 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31393518 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18182463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12028325 — Surrogate Endpoint (SUR): Blood pressure
Study 24439929 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17576388 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7930484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7930484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7930484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23184014 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 23184014 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 19001559 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 14676459 — Surrogate Endpoint (SUR): Bone mineral density
Study 20644555 — Predictive Biomarker (PRD): SERPINB1 mRNA
Genes: SERPINB1; ELANH2; MNEI; PI2
Study 20644555 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 15114435 — Safety Biomarker (SAF): DRD2
Study 11978148 — Surrogate Endpoint (SUR): Blood pressure
Study 19548273 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 18257185 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10381299 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30845346 — Surrogate Endpoint (SUR): Blood pressure
Study 27400947 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27400947 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27400947 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22102056 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31954837 — Surrogate Endpoint (SUR): Blood pressure
Study 29444778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29444778 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25128283 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19385024 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 7916546 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 2589241 — Surrogate Endpoint (SUR): Blood pressure
Study 26743856 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26743856 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26743856 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 16424116 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21284481 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 21284481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21284481 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16425182 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16425182 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10843245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1568575 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27043681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10098822 — Surrogate Endpoint (SUR): Blood pressure
Study 9891896 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 2260915 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21752315 — Surrogate Endpoint (SUR): Serum creatinine
Study 12475455 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 27100440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27100440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22234404 — Surrogate Endpoint (SUR): Blood pressure
Study 15638877 — Surrogate Endpoint (SUR): Serum calcium
Study 2271089 — Surrogate Endpoint (SUR): Serum creatinine
Study 26606263 — Surrogate Endpoint (SUR): Blood pressure
Study 15105059 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 25306290 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25306290 — Surrogate Endpoint (SUR): Blood pressure
Study 24008977 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24008977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21771256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21771256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15148541 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 15148541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10364087 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8645434 — Surrogate Endpoint (SUR): Bone mineral density
Study 8645434 — Surrogate Endpoint (SUR): Blood pressure
Study 6416018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31521192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31521192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29071949 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25175124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9671997 — Surrogate Endpoint (SUR): Bacterial count
Study 28645473 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24595903 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24595903 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24595903 — Surrogate Endpoint (SUR): Blood pressure
Study 19793846 — Surrogate Endpoint (SUR): Blood pressure
Study 15213709 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 3521208 — Surrogate Endpoint (SUR): Blood pressure
Study 3521208 — Surrogate Endpoint (SUR): Serum potassium
Study 30552248 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8902551 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8902551 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 26984485 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 12617614 — Safety Biomarker (SAF): Reactive oxygen species
Study 1317764 — Surrogate Endpoint (SUR): Blood pressure