TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02321267 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04934605 — Predictive Biomarker (PRD): SLC26A4 mRNA
Genes: SLC26A4; PDS
Study NCT03548844 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT03668171 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03783351 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03770572 — Predictive Biomarker (PRD): CLN3 mRNA
Genes: CLN3; BTS
Study NCT01179594 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05637424 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study NCT05637424 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT05637424 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT05637424 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00301353 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03293069 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03293069 — Pharmacodynamic Biomarker (PDY): Guanine nucleotide exchange factor C9orf72
Genes: C9orf72; DENND9; DENNL72
Study NCT05235841 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04845581 — Predictive Biomarker (PRD): SGTA mRNA
Genes: SGTA; SGT; SGT1
Study NCT00783263 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02933411 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04387253 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02129179 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00746785 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study NCT01402648 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01402648 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT03308747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03308747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04692246 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04692246 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01771445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01771445 — Safety Biomarker (SAF): Interleukin 1
Study NCT01771445 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02625285 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT00004478 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02252081 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT02252081 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03729245 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT03939871 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03722875 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03148015 — Predictive Biomarker (PRD): ATP2B2 mRNA
Genes: ATP2B2; PMCA2
Study NCT00403455 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study NCT00403455 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study NCT03009318 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00556413 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00522717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04004013 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00016549 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03272009 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT04710186 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00791596 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT04216836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01324739 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02652468 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01429376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01650272 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT01992744 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01992744 — Safety Biomarker (SAF): BDNF
Study NCT04784468 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03430466 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03430466 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03574402 — Predictive Biomarker (PRD): TP53INP2 mRNA
Genes: TP53INP2; C20orf110; DOR; PINH
Study NCT02175511 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04277364 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT04543565 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04256369 — Surrogate Endpoint (SUR): Serum potassium
Study NCT03231371 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study NCT00342524 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01222533 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04365166 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04365166 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04365166 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study NCT01747005 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT01747005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00541762 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT03698370 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00933387 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00933387 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01440829 — Surrogate Endpoint (SUR): Plasma ammonia
Study NCT00508274 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00508274 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04296721 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00417430 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02941666 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00685828 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT00685828 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study NCT03480295 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03480295 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02999633 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04397419 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00005469 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04106570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02354547 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01169389 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01134380 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04939792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03277677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03277677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03277677 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT02924012 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01585441 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT03507738 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02191527 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04361968 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT00005569 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study NCT01424865 — Predictive Biomarker (PRD): ALDH1A1 mRNA
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study NCT01424865 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01973556 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02670668 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04476914 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02500446 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04147806 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT00235287 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04481646 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03287427 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03287427 — Predictive Biomarker (PRD): MYB mRNA
Genes: MYB
Study NCT01650389 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01650389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04972890 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04972890 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02042014 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00406406 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study NCT01617798 — Surrogate Endpoint (SUR): Serum sodium
Study NCT03268057 — Predictive Biomarker (PRD): SEMA4D mRNA
Genes: SEMA4D; C9orf164; CD100; SEMAJ
Study NCT00257907 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00257907 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00257907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00257907 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03281083 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03281083 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT03281083 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03281083 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00620113 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02973516 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT02461966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT03972189 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT04417010 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00739609 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT02023814 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02023814 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01106235 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study NCT00694460 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03970135 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT01937611 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04198948 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00409435 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04876326 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04876326 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03909724 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03909724 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03909724 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02211209 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04820465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03556020 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT03317119 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT03317119 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03087292 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01545427 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study NCT01831141 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT01831141 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT00375765 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT02821754 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02821754 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02610140 — Predictive Biomarker (PRD): MTLN mRNA
Genes: MTLN; LEMP; LINC00116; MOXI; MPM; NCRNA00116; SMIM37
Study NCT05581836 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT02414347 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02869945 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02589119 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01110291 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT01110291 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT01110291 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02617589 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00941642 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01019850 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT02582385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02582385 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT02582385 — Safety Biomarker (SAF): Interleukin 1
Study NCT02582385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02734472 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00580905 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02713737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02948751 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04383288 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT01975389 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01975389 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02444689 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00256516 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01867086 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03792568 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02180841 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02527733 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02527733 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00802893 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02406404 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02300519 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study NCT01818284 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02277197 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02277197 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02277197 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT02277197 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02056002 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03887169 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study NCT03695822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02164006 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01347203 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00906542 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00906542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02460198 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02460198 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02460198 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT02460198 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02460198 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01870011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03194633 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03222414 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05993962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01100203 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01317888 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01378494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01378494 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01378494 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01378494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01378494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00316498 — Predictive Biomarker (PRD): OGT mRNA
Genes: OGT
Study NCT00189904 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04502836 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT03698214 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04079881 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00894998 — Predictive Biomarker (PRD): TTPA mRNA
Genes: TTPA; TPP1
Study NCT03331744 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study NCT04401228 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01431508 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01609556 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT03336008 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study NCT02055872 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01699711 — Predictive Biomarker (PRD): DYRK1A mRNA
Genes: DYRK1A; DYRK; MNB; MNBH
Study NCT04556318 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00723125 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00723125 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT05290012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05290012 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04690478 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04150471 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04150471 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00820222 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00000466 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00000466 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00569868 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT02528292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02528292 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study NCT02942342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02942342 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00778921 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04918069 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study NCT04918069 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study NCT03401060 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04265027 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02531633 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT02531633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03278327 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study NCT04367740 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS