TrialPanorama/TrialPanorama-database huggingface dataset:
Study 2111252 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 31508730 — Surrogate Endpoint (SUR): Blood pressure
Study 28459941 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28459941 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28459941 — Predictive Biomarker (PRD): Hormone receptor
Study 15290001 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 30823946 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30823946 — Monitoring Biomarker (MOI): Procalcitonin
Study 30823946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30823946 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25109244 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 25109244 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8653998 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26905786 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 26905786 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 19237657 — Surrogate Endpoint (SUR): Serum creatinine
Study 11136142 — Surrogate Endpoint (SUR): Blood pressure
Study 12438291 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30414864 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 30414864 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19692630 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11133370 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8117053 — Surrogate Endpoint (SUR): Blood pressure
Study 17563395 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7826431 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7826431 — Surrogate Endpoint (SUR): Blood pressure
Study 2969860 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2969860 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 21649590 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21649590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21649590 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19347385 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3773141 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3773141 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26288364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12174030 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12174030 — Surrogate Endpoint (SUR): Blood pressure
Study 7843746 — Surrogate Endpoint (SUR): Blood pressure
Study 25844322 — Predictive Biomarker (PRD): CA3 mRNA
Genes: CA3
Study 1671380 — Surrogate Endpoint (SUR): Blood pressure
Study 29071873 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24512909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20976257 — Surrogate Endpoint (SUR): Blood pressure
Study 15787665 — Surrogate Endpoint (SUR): Blood pressure
Study 1672488 — Surrogate Endpoint (SUR): Blood pressure
Study 29021285 — Predictive Biomarker (PRD): LRP2 mRNA
Genes: LRP2
Study 29021285 — Predictive Biomarker (PRD): CUBN mRNA
Genes: CUBN; IFCR
Study 29021285 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 29021285 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 29021285 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 23591659 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23591659 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 7990020 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12825305 — Surrogate Endpoint (SUR): Blood pressure
Study 31096309 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 19204218 — Surrogate Endpoint (SUR): Blood pressure
Study 17381533 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 8090456 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 2682023 — Surrogate Endpoint (SUR): Blood pressure
Study 2682023 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29117238 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29117238 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24476776 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24476776 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31801993 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 25197025 — Predictive Biomarker (PRD): GCGR mRNA
Genes: GCGR
Study 21957896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9354525 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27144545 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27144545 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20538698 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18795588 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8599316 — Surrogate Endpoint (SUR): Serum calcium
Study 18946061 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31003911 — Predictive Biomarker (PRD): Microsatellite instability
Study 15088127 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15088127 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11418230 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30814028 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16441475 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 12940870 — Surrogate Endpoint (SUR): Blood pressure
Study 8885206 — Surrogate Endpoint (SUR): Blood pressure
Study 1396619 — Surrogate Endpoint (SUR): Blood pressure
Study 1396619 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27173785 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 27173785 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 27173785 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 18441454 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18441454 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10973391 — Surrogate Endpoint (SUR): Blood pressure
Study 1620908 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26614144 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 17119520 — Surrogate Endpoint (SUR): Blood pressure
Study 11510804 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11510804 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 9764780 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3296353 — Surrogate Endpoint (SUR): Blood pressure
Study 23799692 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22248893 — Surrogate Endpoint (SUR): Blood pressure
Study 10834773 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 8226001 — Surrogate Endpoint (SUR): Blood pressure
Study 24976224 — Surrogate Endpoint (SUR): Serum creatinine
Study 22313793 — Surrogate Endpoint (SUR): Blood pressure
Study 10696629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24891337 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21276681 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8343321 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 14717059 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 1325772 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31600368 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31600368 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24758565 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 24758565 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 24758565 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 17875241 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 16076378 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 10573104 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31923303 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29608336 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 19083105 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15506067 — Surrogate Endpoint (SUR): Blood pressure
Study 10865218 — Surrogate Endpoint (SUR): Bone mineral density
Study 23834545 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 27161257 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24878421 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 23107220 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24035168 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24035168 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16644439 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 12553385 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 7767541 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 25476074 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22030597 — Surrogate Endpoint (SUR): Blood pressure
Study 12219873 — Surrogate Endpoint (SUR): Blood pressure
Study 973982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30285186 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 28675091 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2921100 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2921100 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 19483074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29509929 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23418154 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 18376181 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 14585524 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14585524 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27460108 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 15695500 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 23653274 — Predictive Biomarker (PRD): RAB8A mRNA
Genes: RAB8A; MEL; RAB8
Study 20046574 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 20046574 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17287448 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 3359658 — Surrogate Endpoint (SUR): Blood pressure
Study 27219520 — Surrogate Endpoint (SUR): Blood pressure
Study 24942611 — Surrogate Endpoint (SUR): Blood pressure
Study 16995860 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10750566 — Surrogate Endpoint (SUR): Bone mineral density
Study 9363656 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 29921800 — Predictive Biomarker (PRD): ADCY3 mRNA
Genes: ADCY3; KIAA0511
Study 30529477 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 17668881 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 17668881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7907871 — Surrogate Endpoint (SUR): Blood pressure
Study 31340800 — Surrogate Endpoint (SUR): Blood pressure
Study 25147236 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19689480 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22237735 — Surrogate Endpoint (SUR): Serum creatinine
Study 19719746 — Surrogate Endpoint (SUR): Blood pressure
Study 9535143 — Surrogate Endpoint (SUR): Blood pressure
Study 2551565 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2551565 — Surrogate Endpoint (SUR): Blood pressure
Study 23211558 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 19592054 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 19592054 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19592054 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11913478 — Surrogate Endpoint (SUR): Blood pressure
Study 26571184 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24134424 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 20090562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16380824 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 15538040 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15538040 — Predictive Biomarker (PRD): Hormone receptor
Study 15538040 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15538040 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15538040 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18487998 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18487998 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 11485281 — Surrogate Endpoint (SUR): Blood pressure
Study 17714844 — Surrogate Endpoint (SUR): Blood pressure
Study 31967673 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30657852 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28081369 — Surrogate Endpoint (SUR): Blood pressure
Study 31394939 — Surrogate Endpoint (SUR): Blood pressure
Study 20383874 — Surrogate Endpoint (SUR): Serum creatinine
Study 28301292 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25062900 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25062900 — Safety Biomarker (SAF): BDNF
Study 21994354 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 21994354 — Predictive Biomarker (PRD): CLSTN3 mRNA
Genes: CLSTN3; CS3; KIAA0726
Study 30922017 — Predictive Biomarker (PRD): SHB mRNA
Genes: SHB
Study 25618418 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25618418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25618418 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25209550 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25209550 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20078871 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8681312 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 8681312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31082512 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 20807094 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 20807094 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 17984165 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17984165 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17984165 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17984165 — Surrogate Endpoint (SUR): Blood pressure
Study 17984165 — Surrogate Endpoint (SUR): Serum potassium
Study 17984165 — Surrogate Endpoint (SUR): Serum sodium
Study 10495176 — Surrogate Endpoint (SUR): Blood pressure
Study 8543208 — Surrogate Endpoint (SUR): Blood pressure
Study 1961959 — Surrogate Endpoint (SUR): Blood pressure
Study 31737175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31737175 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 31737175 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26019129 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24754047 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24754047 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20854735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20854735 — Monitoring Biomarker (MOI): Procalcitonin
Study 20854735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20854735 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29660207 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 20416130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8382753 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28750917 — Monitoring Biomarker (MOI): HBV DNA
Study 22448738 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 792688 — Monitoring Biomarker (MOI): Complement C4
Study 24624380 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 21390543 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19131891 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11430936 — Surrogate Endpoint (SUR): Blood pressure
Study 9601653 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 20494902 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20494902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16919926 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9626806 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22129607 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22129607 — Surrogate Endpoint (SUR): Blood pressure
Study 20514078 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 19892046 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7904847 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 3323596 — Surrogate Endpoint (SUR): Serum creatinine
Study 3323596 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24177203 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10375084 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 7358202 — Surrogate Endpoint (SUR): Blood pressure
Study 25658017 — Surrogate Endpoint (SUR): Urine free cortisol
Study 18830236 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 16921503 — Safety Biomarker (SAF): Interleukin 1
Study 10364988 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26859491 — Surrogate Endpoint (SUR): Blood pressure
Study 19282241 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 16387079 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 12218339 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12218339 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31723956 — Surrogate Endpoint (SUR): Blood pressure
Study 10903022 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10903022 — Surrogate Endpoint (SUR): Serum sodium
Study 17414400 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 11953964 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 19808296 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16772327 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16772327 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26467209 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26467209 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 29264729 — Surrogate Endpoint (SUR): Blood pressure
Study 20350693 — Surrogate Endpoint (SUR): Serum creatinine
Study 17967134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17967134 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 14586719 — Surrogate Endpoint (SUR): Blood pressure
Study 14586719 — Surrogate Endpoint (SUR): Serum creatinine
Study 20535265 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16148375 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31504721 — Surrogate Endpoint (SUR): Blood pressure
Study 22270485 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22270485 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19571529 — Surrogate Endpoint (SUR): Blood pressure
Study 9557374 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 229506 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31099281 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19264686 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 10365647 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8963479 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15821826 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1971540 — Surrogate Endpoint (SUR): Blood pressure
Study 21464051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19432546 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 19432546 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4