TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10357120 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 30683945 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19169684 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 7896423 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 30187612 — Monitoring Biomarker (MOI): HBV DNA
Study 18042476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8389269 — Surrogate Endpoint (SUR): Blood pressure
Study 8389269 — Surrogate Endpoint (SUR): Bacterial count
Study 18323476 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29907082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22317271 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18226045 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18226045 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8703452 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31201218 — Surrogate Endpoint (SUR): Serum potassium
Study 22935482 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18496484 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18496484 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18496484 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29843500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29843500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23816960 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23816960 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16352489 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16352489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19477358 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 19477358 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 15014819 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 328328 — Surrogate Endpoint (SUR): Blood pressure
Study 19805640 — Surrogate Endpoint (SUR): Blood pressure
Study 22994061 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22994061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16167938 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 18317392 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 11995347 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 27178566 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27178566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27178566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21648052 — Surrogate Endpoint (SUR): Blood pressure
Study 20165744 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18062519 — Surrogate Endpoint (SUR): Blood pressure
Study 12068252 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 23943299 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18985146 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9243107 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8500516 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 12638028 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 12638028 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23834479 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19522023 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 19522023 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 3207528 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22048557 — Surrogate Endpoint (SUR): Bone mineral density
Study 28028076 — Predictive Biomarker (PRD): FNDC5 mRNA
Genes: FNDC5; FRCP2
Study 12577354 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 1426320 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 6320627 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6320627 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29869538 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29971527 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 29971527 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 25218552 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8695248 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26708006 — Surrogate Endpoint (SUR): Blood pressure
Study 18095238 — Surrogate Endpoint (SUR): Blood pressure
Study 18095238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18095238 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8832493 — Surrogate Endpoint (SUR): Blood pressure
Study 29507938 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27764725 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25241758 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 20491843 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18025765 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2330929 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 30810700 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 28151412 — Surrogate Endpoint (SUR): Blood pressure
Study 24299607 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 12954578 — Predictive Biomarker (PRD): Hormone receptor
Study 8441838 — Surrogate Endpoint (SUR): Serum creatinine
Study 23796946 — Surrogate Endpoint (SUR): Blood pressure
Study 23796946 — Safety Biomarker (SAF): BDNF
Study 20724426 — Surrogate Endpoint (SUR): Serum creatinine
Study 9329413 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 29362512 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 29362512 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 29362512 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 29362512 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 29362512 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 29241617 — Surrogate Endpoint (SUR): Blood pressure
Study 7798165 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30096258 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 30096258 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30096258 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20861820 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20861820 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 20861820 — Surrogate Endpoint (SUR): Serum calcium
Study 10511327 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7865226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7865226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25881455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25881455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25881455 — Surrogate Endpoint (SUR): Serum creatinine
Study 25881455 — Surrogate Endpoint (SUR): Serum uric acid
Study 25881455 — Safety Biomarker (SAF): Urinary microalbumin
Study 15656877 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 15656877 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7530507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7530507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7530507 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 24621065 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24621065 — Safety Biomarker (SAF): BDNF
Study 23909679 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23909679 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21792626 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21792626 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21792626 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21792626 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 3625417 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 18375318 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15262194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24336330 — Predictive Biomarker (PRD): TGFBR2 mRNA
Genes: TGFBR2
Study 24336330 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 9209998 — Surrogate Endpoint (SUR): Bacterial count
Study 23052111 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12659243 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 21999668 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 27716125 — Predictive Biomarker (PRD): DARS1 mRNA
Genes: DARS1; DARS; PIG40
Study 16208152 — Surrogate Endpoint (SUR): Blood pressure
Study 26713333 — Surrogate Endpoint (SUR): Bone mineral density
Study 26713333 — Surrogate Endpoint (SUR): Serum calcium
Study 26713333 — Surrogate Endpoint (SUR): Serum creatinine
Study 25205864 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 25205864 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 25205864 — Predictive Biomarker (PRD): TRIB1 mRNA
Genes: TRIB1; C8FW; GIG2; TRB1
Study 25205864 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 20628384 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8788597 — Safety Biomarker (SAF): 51Cr-EDTA
Study 1345050 — Surrogate Endpoint (SUR): Blood pressure
Study 17973865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11502777 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11502777 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9266258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9266258 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9266258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7508066 — Surrogate Endpoint (SUR): Blood pressure
Study 7508066 — Surrogate Endpoint (SUR): Urinary oxalate
Study 31976548 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28887192 — Surrogate Endpoint (SUR): Blood pressure
Study 11369660 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 8282621 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 8282621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18199590 — Surrogate Endpoint (SUR): Blood pressure
Study 9239992 — Surrogate Endpoint (SUR): Serum testosterone
Study 23248072 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 12670781 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8776642 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8776642 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8776642 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8776642 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20980923 — Surrogate Endpoint (SUR): Bone mineral density
Study 28222742 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 16032784 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2454361 — Surrogate Endpoint (SUR): Blood pressure
Study 27046472 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25525981 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25525981 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 20420579 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15625365 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27050538 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 22353022 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22353022 — Surrogate Endpoint (SUR): Bone mineral density
Study 19965682 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 16282540 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 9481631 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 369471 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31315417 — Surrogate Endpoint (SUR): Blood pressure
Study 23644921 — Surrogate Endpoint (SUR): Blood pressure
Study 19894301 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 16996599 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 15207200 — Surrogate Endpoint (SUR): Blood pressure
Study 9102059 — Surrogate Endpoint (SUR): Bone mineral density
Study 8110036 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22289649 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 27920258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18795255 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 15088288 — Safety Biomarker (SAF): Interleukin 1
Study 8155091 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19096005 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 12034159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28750942 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 28750942 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 28750942 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21751854 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17361520 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 6702863 — Surrogate Endpoint (SUR): Blood pressure
Study 30066937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27217345 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 27180444 — Surrogate Endpoint (SUR): Blood pressure
Study 21148499 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10880159 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18794646 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 26899537 — Surrogate Endpoint (SUR): Serum creatinine
Study 23214255 — Surrogate Endpoint (SUR): Serum testosterone
Study 9156960 — Surrogate Endpoint (SUR): Blood pressure
Study 17893569 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17893569 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 16371039 — Predictive Biomarker (PRD): NAAA mRNA
Genes: NAAA; ASAHL; PLT
Study 9607383 — Surrogate Endpoint (SUR): Blood pressure
Study 1700218 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1700218 — Surrogate Endpoint (SUR): Blood pressure
Study 30515978 — Surrogate Endpoint (SUR): Blood pressure
Study 21654265 — Surrogate Endpoint (SUR): Serum uric acid
Study 19494806 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 19494806 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 19494806 — Predictive Biomarker (PRD): NR4A2 mRNA
Genes: NR4A2; NOT; NURR1; TINUR
Study 9776870 — Surrogate Endpoint (SUR): Blood pressure
Study 2659720 — Safety Biomarker (SAF): 51Cr-EDTA
Study 21306457 — Surrogate Endpoint (SUR): Blood pressure
Study 11806881 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2124097 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2124097 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22067309 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17533389 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 11503007 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11503007 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 30301127 — Surrogate Endpoint (SUR): Blood pressure
Study 30301127 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30301127 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12534358 — Surrogate Endpoint (SUR): Serum testosterone
Study 12534358 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12534358 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30005705 — Predictive Biomarker (PRD): SLC25A3 mRNA
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 19845074 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19845074 — Surrogate Endpoint (SUR): Blood pressure
Study 9787148 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 29455421 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 26666738 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9223116 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 28492790 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16501036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23280682 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 18474494 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3522003 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25137867 — Surrogate Endpoint (SUR): Blood pressure
Study 16639677 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 16639677 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 14583417 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10981244 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2539286 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2539286 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26124653 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 10924313 — Surrogate Endpoint (SUR): Blood pressure
Study 8458181 — Surrogate Endpoint (SUR): Blood pressure
Study 24246414 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22563751 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22563751 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 22563751 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18607941 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 10939028 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10939028 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27053769 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24222194 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20979470 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19334373 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16043939 — Surrogate Endpoint (SUR): Blood pressure
Study 10520404 — Surrogate Endpoint (SUR): Blood pressure
Study 9651906 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9651906 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24119735 — Monitoring Biomarker (MOI): HBV DNA
Study 6830569 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 24661167 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 29399993 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 25706652 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12495164 — Surrogate Endpoint (SUR): Blood pressure
Study 24916013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24916013 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23643564 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 21666543 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19635338 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 19635338 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 17109336 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17109336 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17109336 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15236274 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8185426 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29770466 — Surrogate Endpoint (SUR): Sperm parameters
Study 24709463 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 20843662 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19938160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9437182 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8101194 — Surrogate Endpoint (SUR): Blood pressure
Study 8101194 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29799827 — Safety Biomarker (SAF): Hyaluronic acid
Study 27115157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25273342 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL