TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31735328 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30624150 — Surrogate Endpoint (SUR): Blood pressure
Study 19691566 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12764909 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12764909 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11421893 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 7506322 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7506322 — Safety Biomarker (SAF): 51Cr-EDTA
Study 7506322 — Surrogate Endpoint (SUR): Blood pressure
Study 336257 — Surrogate Endpoint (SUR): Blood pressure
Study 20220747 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 20220747 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 20220747 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 20220747 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 20467528 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15646732 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15646732 — Surrogate Endpoint (SUR): Blood pressure
Study 9510396 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31922998 — Surrogate Endpoint (SUR): Serum creatinine
Study 28329211 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21209231 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9634262 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9634262 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1968233 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19167712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19167712 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15502038 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11522179 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7945560 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29813097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27578110 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 25703424 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25703424 — Surrogate Endpoint (SUR): Blood pressure
Study 20384434 — Predictive Biomarker (PRD): IGF2BP2 mRNA
Genes: IGF2BP2; IMP2; VICKZ2
Study 20384434 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 30069604 — Surrogate Endpoint (SUR): Blood pressure
Study 23489301 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9595286 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9595286 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9595286 — Surrogate Endpoint (SUR): Blood pressure
Study 7801667 — Surrogate Endpoint (SUR): Blood pressure
Study 3514833 — Surrogate Endpoint (SUR): Serum calcium
Study 3514833 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 25762401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25762401 — Safety Biomarker (SAF): IL-6 and IL-10
Study 25762401 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19798074 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19798074 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18634501 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10559092 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30008589 — Monitoring Biomarker (MOI): HBV DNA
Study 8617079 — Surrogate Endpoint (SUR): Serum potassium
Study 12161494 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12161494 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 12161494 — Surrogate Endpoint (SUR): Blood pressure
Study 17217362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15961699 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 2523264 — Surrogate Endpoint (SUR): Blood pressure
Study 31690775 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 31690775 — Surrogate Endpoint (SUR): Blood pressure
Study 24824014 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18395165 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9583927 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30256277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30256277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30256277 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30256277 — Safety Biomarker (SAF): BDNF
Study 30256277 — Safety Biomarker (SAF): Reactive oxygen species
Study 15713907 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 1874208 — Surrogate Endpoint (SUR): Blood pressure
Study 16129973 — Surrogate Endpoint (SUR): Blood pressure
Study 29092881 — Surrogate Endpoint (SUR): Serum potassium
Study 28306389 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28306389 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22965965 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22965965 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15194675 — Safety Biomarker (SAF): Reactive oxygen species
Study 8483096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 16027343 — Safety Biomarker (SAF): Hyaluronic acid
Study 27040362 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20077495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17611706 — Surrogate Endpoint (SUR): Bone mineral density
Study 15860392 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15860392 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7851363 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 31812328 — Predictive Biomarker (PRD): EMSY mRNA
Genes: EMSY; C11orf30; GL002
Study 31812328 — Predictive Biomarker (PRD): LRRC32 mRNA
Genes: LRRC32; D11S833E
Study 23842710 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 20110024 — Surrogate Endpoint (SUR): Blood pressure
Study 1580283 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1580283 — Surrogate Endpoint (SUR): Blood pressure
Study 1580283 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27615041 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9454908 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 1710743 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1710743 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8147328 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8147328 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31045229 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 28555011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20089776 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 18054638 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 16076991 — Surrogate Endpoint (SUR): Blood pressure
Study 12242580 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 30770586 — Surrogate Endpoint (SUR): Blood pressure
Study 23714773 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2948929 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15708698 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8933493 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8933493 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 8933493 — Surrogate Endpoint (SUR): Blood pressure
Study 27032639 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27032639 — Surrogate Endpoint (SUR): Serum creatinine
Study 27032639 — Surrogate Endpoint (SUR): Blood pressure
Study 7702795 — Surrogate Endpoint (SUR): Blood pressure
Study 3667138 — Surrogate Endpoint (SUR): Blood pressure
Study 25499939 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25499939 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18007158 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12358134 — Surrogate Endpoint (SUR): Blood pressure
Study 7488277 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 7034472 — Surrogate Endpoint (SUR): Blood pressure
Study 11908559 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30779597 — Surrogate Endpoint (SUR): Blood pressure
Study 12450893 — Surrogate Endpoint (SUR): Plasma sitosterol and campesterol
Study 7670096 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20953684 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20953684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20953684 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12110340 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 8737889 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3904334 — Surrogate Endpoint (SUR): Blood pressure
Study 29663044 — Monitoring Biomarker (MOI): Procalcitonin
Study 26469139 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26469139 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 12797485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8803515 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8803515 — Surrogate Endpoint (SUR): Blood pressure
Study 8803515 — Surrogate Endpoint (SUR): Serum creatinine
Study 31944806 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23815533 — Surrogate Endpoint (SUR): Blood pressure
Study 17359512 — Surrogate Endpoint (SUR): Serum creatinine
Study 17359512 — Surrogate Endpoint (SUR): Blood pressure
Study 12514902 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2647187 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7894226 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 31863284 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 30653533 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 28228114 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 2083193 — Surrogate Endpoint (SUR): Blood pressure
Study 30714233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30714233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26003637 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15515782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15515782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30142760 — Surrogate Endpoint (SUR): Blood pressure
Study 16491216 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 12854150 — Monitoring Biomarker (MOI): HBV DNA
Study 2005316 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7022275 — Surrogate Endpoint (SUR): Blood pressure
Study 28886024 — Surrogate Endpoint (SUR): Serum testosterone
Study 21345662 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17363767 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 17363767 — Predictive Biomarker (PRD): EPHX1 mRNA
Genes: EPHX1; EPHX; EPOX
Study 17363767 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 25635977 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18667327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18667327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18667327 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 18667327 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8863992 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8863992 — Safety Biomarker (SAF): Type I cytoskeletal 18 Keratin
Genes: KRT18; CYK18; PIG46
Study 30782343 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 30035339 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 18753091 — Surrogate Endpoint (SUR): Blood pressure
Study 8697930 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 809046 — Surrogate Endpoint (SUR): Blood pressure
Study 24725369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24183127 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 18259100 — Surrogate Endpoint (SUR): Serum calcium
Study 31584739 — Surrogate Endpoint (SUR): Serum potassium
Study 23616506 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 15020604 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9727818 — Surrogate Endpoint (SUR): Blood pressure
Study 12888056 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12510249 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10727543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10727543 — Surrogate Endpoint (SUR): Serum creatinine
Study 10727543 — Surrogate Endpoint (SUR): Blood pressure
Study 6542082 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 19913895 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 24222260 — Surrogate Endpoint (SUR): Blood pressure
Study 25607226 — Surrogate Endpoint (SUR): Blood pressure
Study 8050210 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 25579292 — Surrogate Endpoint (SUR): Blood pressure
Study 18306478 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18306478 — Surrogate Endpoint (SUR): Bone mineral density
Study 18306478 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16957412 — Surrogate Endpoint (SUR): Blood pressure
Study 16957412 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10828571 — Surrogate Endpoint (SUR): Blood pressure
Study 30421481 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30421481 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30421481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26787116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15156426 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28689647 — Surrogate Endpoint (SUR): Blood pressure
Study 24215511 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 24215511 — Predictive Biomarker (PRD): RRM2B mRNA
Genes: RRM2B; P53R2
Study 18165600 — Surrogate Endpoint (SUR): Blood pressure
Study 16728515 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16728515 — Surrogate Endpoint (SUR): Blood pressure
Study 8512762 — Surrogate Endpoint (SUR): Blood pressure
Study 25981191 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 25981191 — Safety Biomarker (SAF): Th2 cell
Study 25981191 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 10633535 — Surrogate Endpoint (SUR): Serum testosterone
Study 15894964 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15894964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7994982 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7994982 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 7994982 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7994982 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 7994982 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31722313 — Predictive Biomarker (PRD): ADARB1 mRNA
Genes: ADARB1; ADAR2; DRADA2; RED1
Study 31722313 — Predictive Biomarker (PRD): GRIA2 mRNA
Genes: GRIA2; GLUR2
Study 10926587 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 9594145 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 9594145 — Surrogate Endpoint (SUR): Blood pressure
Study 9594145 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29449079 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24997050 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 10027655 — Surrogate Endpoint (SUR): Blood pressure
Study 7595704 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28103698 — Surrogate Endpoint (SUR): Blood pressure
Study 26580986 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 25027109 — Surrogate Endpoint (SUR): Bone mineral density
Study 19411087 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9741502 — Surrogate Endpoint (SUR): Blood pressure
Study 28161119 — Surrogate Endpoint (SUR): Bone mineral density
Study 21951411 — Surrogate Endpoint (SUR): Blood pressure
Study 21951411 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19112213 — Surrogate Endpoint (SUR): Blood pressure
Study 21358850 — Surrogate Endpoint (SUR): Blood pressure
Study 7762498 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 371902 — Surrogate Endpoint (SUR): Blood pressure
Study 30706788 — Surrogate Endpoint (SUR): Blood pressure
Study 22547439 — Surrogate Endpoint (SUR): Blood pressure
Study 12139821 — Surrogate Endpoint (SUR): Blood pressure
Study 26555069 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 26555069 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17347181 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 16797292 — Surrogate Endpoint (SUR): Blood pressure
Study 16797292 — Surrogate Endpoint (SUR): Serum creatinine
Study 15012700 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 15012700 — Surrogate Endpoint (SUR): Blood pressure
Study 26519056 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 26519056 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 26519056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26519056 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 17277585 — Predictive Biomarker (PRD): ADRA2B mRNA
Genes: ADRA2B; ADRA2L1; ADRA2RL1
Study 9750705 — Surrogate Endpoint (SUR): Blood pressure
Study 28679524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28679524 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31564281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31564281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31564281 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19357698 — Surrogate Endpoint (SUR): Blood pressure
Study 15136065 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28646900 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 15133865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30823563 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 17229901 — Surrogate Endpoint (SUR): Blood pressure
Study 12774015 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 3710631 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3710631 — Surrogate Endpoint (SUR): Blood pressure
Study 2554630 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 30415628 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26572686 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24924261 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 28267470 — Surrogate Endpoint (SUR): Blood pressure
Study 25924844 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31967515 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 28893433 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28893433 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 28893433 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 23079125 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12087923 — Surrogate Endpoint (SUR): Blood pressure
Study 20571496 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20571496 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20571496 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20571496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10438047 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26440636 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23356886 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9681723 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 9681723 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14