TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29893791 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16552548 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 14667889 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16095529 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 16095529 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 16095529 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 16095529 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 16095529 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 16095529 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12417542 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27026148 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31317471 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 1866045 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 6897039 — Surrogate Endpoint (SUR): Blood pressure
Study 31733647 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31733647 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26818127 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30721208 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16449409 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16449409 — Surrogate Endpoint (SUR): Blood pressure
Study 29621064 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 22492381 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 22492381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22492381 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study 22492381 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 22492381 — Predictive Biomarker (PRD): TUB mRNA
Genes: TUB
Study 22492381 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22492381 — Predictive Biomarker (PRD): MLXIPL mRNA
Genes: MLXIPL; BHLHD14; MIO; WBSCR14
Study 22492381 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study 22492381 — Predictive Biomarker (PRD): PCK2 mRNA
Genes: PCK2; PEPCK2
Study 22492381 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 12091845 — Surrogate Endpoint (SUR): Serum potassium
Study 31897956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27265548 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 17265038 — Surrogate Endpoint (SUR): Blood pressure
Study 28814664 — Surrogate Endpoint (SUR): Blood pressure
Study 22123970 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 24916558 — Surrogate Endpoint (SUR): Blood pressure
Study 15739554 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 12870164 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11285043 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11285043 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8510705 — Surrogate Endpoint (SUR): Blood pressure
Study 25977313 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24168259 — Monitoring Biomarker (MOI): HBV DNA
Study 19940005 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19940005 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19940005 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24953333 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17044764 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 27917214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27917214 — Surrogate Endpoint (SUR): Bone mineral density
Study 27917214 — Surrogate Endpoint (SUR): Serum calcium
Study 27917214 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27917214 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27917214 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 27917214 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27917214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27917214 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31928758 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10996576 — Surrogate Endpoint (SUR): Bone mineral density
Study 11344712 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 9046389 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9046389 — Surrogate Endpoint (SUR): Blood pressure
Study 9046389 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29659952 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 29659952 — Surrogate Endpoint (SUR): Blood pressure
Study 21176107 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 9604732 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29995693 — Surrogate Endpoint (SUR): Blood pressure
Study 7102537 — Surrogate Endpoint (SUR): Blood pressure
Study 19641491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19641491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12126265 — Surrogate Endpoint (SUR): Blood pressure
Study 9508173 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1071668 — Surrogate Endpoint (SUR): Blood pressure
Study 30564892 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22968811 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 17143135 — Surrogate Endpoint (SUR): Blood pressure
Study 17143135 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3549811 — Surrogate Endpoint (SUR): Blood pressure
Study 31269890 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31269890 — Safety Biomarker (SAF): BDNF
Study 12736156 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12736156 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11053512 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 27522631 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18242141 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11035615 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11035615 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31594889 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 27709794 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27709794 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22294512 — Surrogate Endpoint (SUR): Serum creatinine
Study 22294512 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 2252123 — Surrogate Endpoint (SUR): Serum creatinine
Study 31072867 — Predictive Biomarker (PRD): GGH mRNA
Genes: GGH
Study 28329190 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 19714296 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 12845504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10685789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10685789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10685789 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10172083 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2736884 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 18258419 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 10866444 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10866444 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9268811 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 25444682 — Surrogate Endpoint (SUR): Blood pressure
Study 16780391 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10865304 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 23716037 — Surrogate Endpoint (SUR): Bone mineral density
Study 10404959 — Surrogate Endpoint (SUR): Blood pressure
Study 31136202 — Surrogate Endpoint (SUR): Serum testosterone
Study 21122856 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 16458215 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 14969664 — Surrogate Endpoint (SUR): Bone mineral density
Study 9815742 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 8179133 — Surrogate Endpoint (SUR): Blood pressure
Study 16424795 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 16424795 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 14976862 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10702763 — Surrogate Endpoint (SUR): Blood pressure
Study 15980684 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15980684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1672843 — Surrogate Endpoint (SUR): Blood pressure
Study 30387144 — Surrogate Endpoint (SUR): Blood pressure
Study 17986290 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 25572773 — Surrogate Endpoint (SUR): Blood pressure
Study 21392609 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21392609 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19673939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19673939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19673939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31172734 — Surrogate Endpoint (SUR): Bone mineral density
Study 26239831 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 23623452 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 18176139 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 23736351 — Predictive Biomarker (PRD): ANKS4B mRNA
Genes: ANKS4B; HARP
Study 19210650 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 3115354 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 12851867 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9082344 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9082344 — Surrogate Endpoint (SUR): Blood pressure
Study 6357257 — Surrogate Endpoint (SUR): Blood pressure
Study 22849607 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19461006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11697813 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 9390050 — Surrogate Endpoint (SUR): Bone mineral density
Study 29282259 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29282259 — Surrogate Endpoint (SUR): Blood pressure
Study 27720650 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24682379 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15220952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15220952 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15220952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17184672 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 11829098 — Surrogate Endpoint (SUR): Serum potassium
Study 72901 — Surrogate Endpoint (SUR): Blood pressure
Study 28420471 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10224729 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 1848679 — Surrogate Endpoint (SUR): Serum creatinine
Study 20530054 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11101059 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26810282 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 21149920 — Monitoring Biomarker (MOI): HBV DNA
Study 12382459 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 21853543 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 20168020 — Surrogate Endpoint (SUR): Blood pressure
Study 24749639 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 24469880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24469880 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 24469880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24886034 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 30454883 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20713883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9396450 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2452123 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2452123 — Monitoring Biomarker (MOI): HBV DNA
Study 23148280 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11214135 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30989339 — Surrogate Endpoint (SUR): Bone mineral density
Study 27631248 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 27631248 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18281662 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 29447787 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 24195609 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24195609 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24195609 — Surrogate Endpoint (SUR): Blood pressure
Study 11397720 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11397720 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2967187 — Surrogate Endpoint (SUR): Blood pressure
Study 28329231 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 28329231 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 28571235 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28571235 — Surrogate Endpoint (SUR): Blood pressure
Study 15246889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15246889 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15246889 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15246889 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11189397 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 1971028 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8820893 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8820893 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25179086 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17578790 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9734748 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 29993297 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 24008606 — Safety Biomarker (SAF): Reactive oxygen species
Study 14758573 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11812703 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31745762 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31745762 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MMP10 mRNA
Genes: MMP10; STMY2
Study 31745762 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 31745762 — Predictive Biomarker (PRD): IL13RA2 mRNA
Genes: IL13RA2; IL13R
Study 31745762 — Predictive Biomarker (PRD): ZCCHC12 mRNA
Genes: ZCCHC12; SIZN1
Study 31745762 — Predictive Biomarker (PRD): SRARP mRNA
Genes: SRARP; C1orf64; ERRF; SSPR
Study 28192673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26317257 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22025580 — Surrogate Endpoint (SUR): Blood pressure
Study 16832022 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 25245113 — Surrogate Endpoint (SUR): Blood pressure
Study 25245113 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23863908 — Surrogate Endpoint (SUR): Blood pressure
Study 21779579 — Surrogate Endpoint (SUR): Blood pressure
Study 8324040 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27483458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15173671 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 25938633 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25938633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15202379 — Surrogate Endpoint (SUR): Blood pressure
Study 31075364 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 20023571 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23239675 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15373937 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 10949098 — Surrogate Endpoint (SUR): Blood pressure
Study 12653258 — Surrogate Endpoint (SUR): Serum sodium
Study 16862245 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 16862245 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 27655646 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26908330 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 26908330 — Predictive Biomarker (PRD): CSF1 mRNA
Genes: CSF1
Study 26908330 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26908330 — Safety Biomarker (SAF): Hepatitis A virus cellular receptor 1
Genes: HAVCR1; KIM1; TIM1; TIMD1
Study 29156488 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 25096769 — Surrogate Endpoint (SUR): Blood pressure
Study 7915916 — Safety Biomarker (SAF): Interleukin 1
Study 31517663 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 26698263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26698263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26698263 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 1571340 — Surrogate Endpoint (SUR): Blood pressure
Study 2856757 — Surrogate Endpoint (SUR): Blood pressure
Study 25311218 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 18547825 — Predictive Biomarker (PRD): A1CF mRNA
Genes: A1CF; ACF; ASP
Study 18547825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7560489 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28425772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28425772 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 29677060 — Surrogate Endpoint (SUR): Blood pressure
Study 23903371 — Surrogate Endpoint (SUR): Serum calcium
Study 23903371 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23903371 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 22171015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2884859 — Surrogate Endpoint (SUR): Blood pressure
Study 2884859 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31813662 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30006861 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28493376 — Surrogate Endpoint (SUR): Blood pressure
Study 16805678 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 8399091 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8399091 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23032322 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 18490845 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2048560 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7665996 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28002447 — Predictive Biomarker (PRD): HTR3A mRNA
Genes: HTR3A; 5HT3R; HTR3
Study 20044242 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27898183 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31302234 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 31302234 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 31302234 — Predictive Biomarker (PRD): CCND2 mRNA
Genes: CCND2
Study 31302234 — Predictive Biomarker (PRD): CCND3 mRNA
Genes: CCND3
Study 31302234 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 23978944 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1