TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26184257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26184257 — Surrogate Endpoint (SUR): Blood pressure
Study 26184257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26184257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12932111 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 8466726 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8466726 — Surrogate Endpoint (SUR): Blood pressure
Study 16422913 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 6426828 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27077693 — Predictive Biomarker (PRD): OTP mRNA
Genes: OTP
Study 7723681 — Surrogate Endpoint (SUR): Serum uric acid
Study 7723681 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25745496 — Surrogate Endpoint (SUR): Blood pressure
Study 22089970 — Predictive Biomarker (PRD): Hormone receptor
Study 11224833 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 15064583 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 24666558 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18390799 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 19395131 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 9818688 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9818688 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 2653593 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24809261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11174617 — Surrogate Endpoint (SUR): Serum creatinine
Study 18465329 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 18465329 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16572117 — Surrogate Endpoint (SUR): Serum creatinine
Study 25351237 — Surrogate Endpoint (SUR): Blood pressure
Study 23551935 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23551935 — Surrogate Endpoint (SUR): Serum sodium
Study 21327593 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18685945 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25064769 — Surrogate Endpoint (SUR): Blood pressure
Study 12453950 — Surrogate Endpoint (SUR): Blood pressure
Study 10362210 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27550914 — Surrogate Endpoint (SUR): Blood pressure
Study 25994549 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23220732 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17942579 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10811074 — Predictive Biomarker (PRD): ETV5 mRNA
Genes: ETV5; ERM
Study 16171663 — Surrogate Endpoint (SUR): Blood pressure
Study 30040033 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17920256 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15197114 — Surrogate Endpoint (SUR): Blood pressure
Study 9589354 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9589354 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9589354 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7920882 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30711862 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 20452196 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 20452196 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20452196 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22799613 — Surrogate Endpoint (SUR): Blood pressure
Study 17278987 — Surrogate Endpoint (SUR): Blood pressure
Study 17278987 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17278987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10964037 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 6095322 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6095322 — Surrogate Endpoint (SUR): Blood pressure
Study 22540269 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 25129551 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 22711428 — Surrogate Endpoint (SUR): Blood pressure
Study 20562609 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 12092746 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27344103 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 24588117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17523968 — Surrogate Endpoint (SUR): Blood pressure
Study 28538644 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 23438677 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19380382 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 15700749 — Surrogate Endpoint (SUR): Blood pressure
Study 21073760 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 18674741 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 18674741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9345419 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24717258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24717258 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 24717258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30337315 — Surrogate Endpoint (SUR): Blood pressure
Study 7835550 — Surrogate Endpoint (SUR): Blood pressure
Study 25211369 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 16235184 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 16235184 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 9928752 — Surrogate Endpoint (SUR): Blood pressure
Study 9928752 — Surrogate Endpoint (SUR): Serum creatinine
Study 28865890 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 21502860 — Safety Biomarker (SAF): Hyaluronic acid
Study 15567095 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11149033 — Surrogate Endpoint (SUR): Blood pressure
Study 11149033 — Surrogate Endpoint (SUR): Serum creatinine
Study 9489083 — Surrogate Endpoint (SUR): Blood pressure
Study 20583919 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 20583919 — Predictive Biomarker (PRD): TKT mRNA
Genes: TKT
Study 12370838 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10077140 — Surrogate Endpoint (SUR): Blood pressure
Study 26540210 — Surrogate Endpoint (SUR): Blood pressure
Study 1706562 — Surrogate Endpoint (SUR): Blood pressure
Study 6765509 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 11168303 — Surrogate Endpoint (SUR): Blood pressure
Study 8200946 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 8200946 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30001903 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 24497828 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24497828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24497828 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 24497828 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 24497828 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24349532 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 18237588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18237588 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9507235 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9507235 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9507235 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31814476 — Surrogate Endpoint (SUR): Blood pressure
Study 21047923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21047923 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 21047923 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 21047923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14714578 — Surrogate Endpoint (SUR): Blood pressure
Study 14714578 — Surrogate Endpoint (SUR): Serum creatinine
Study 1357924 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 30857448 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26938218 — Safety Biomarker (SAF): Carbamoyl-phosphate synthetase I
Genes: CPS1
Study 2105638 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30887496 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 9039155 — Surrogate Endpoint (SUR): Blood pressure
Study 8577634 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 332438 — Surrogate Endpoint (SUR): Blood pressure
Study 27049354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26211623 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 22024276 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 9635947 — Surrogate Endpoint (SUR): Blood pressure
Study 8162627 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28167660 — Surrogate Endpoint (SUR): Bone mineral density
Study 23121681 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18753738 — Surrogate Endpoint (SUR): Serum creatinine
Study 15487810 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9804594 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25190615 — Surrogate Endpoint (SUR): Serum potassium
Study 17218552 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15367512 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9554820 — Surrogate Endpoint (SUR): Serum creatinine
Study 9554820 — Surrogate Endpoint (SUR): Blood pressure
Study 8060471 — Surrogate Endpoint (SUR): Serum creatinine
Study 3137765 — Surrogate Endpoint (SUR): Blood pressure
Study 30920593 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 25196721 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 15571635 — Surrogate Endpoint (SUR): Blood pressure
Study 31931137 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28866140 — Safety Biomarker (SAF): Reactive oxygen species
Study 22520526 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 16681880 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 11784351 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 11784351 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 8249557 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18581440 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1920009 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31519283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31519283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25555385 — Predictive Biomarker (PRD): FTCD mRNA
Genes: FTCD
Study 25555385 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 25555385 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 25555385 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 23816271 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 23816271 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 23816271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 23816271 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 23816271 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 23816271 — Predictive Biomarker (PRD): CXCL16 mRNA
Genes: CXCL16; SCYB16; SRPSOX; UNQ2759/PRO6714
Study 21238470 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21238470 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 21238470 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 17917321 — Surrogate Endpoint (SUR): Blood pressure
Study 15536109 — Surrogate Endpoint (SUR): Blood pressure
Study 7942779 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7942779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 3330987 — Surrogate Endpoint (SUR): Blood pressure
Study 21166828 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 7934491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7934491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23886756 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 21729166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27798329 — Surrogate Endpoint (SUR): Blood pressure
Study 19828470 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 17286233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17286233 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study 17286233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16128937 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 16128937 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study 16128937 — Safety Biomarker (SAF): Interleukin 1
Study 9929085 — Surrogate Endpoint (SUR): Blood pressure
Study 27679519 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 27679519 — Safety Biomarker (SAF): Urinary total protein
Study 24910383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12516830 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 31116151 — Surrogate Endpoint (SUR): Blood pressure
Study 11464687 — Surrogate Endpoint (SUR): Blood pressure
Study 28042082 — Surrogate Endpoint (SUR): Blood pressure
Study 26187617 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28617540 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 15534246 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9314428 — Surrogate Endpoint (SUR): Blood pressure
Study 3946248 — Surrogate Endpoint (SUR): Blood pressure
Study 26890894 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 19080566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16719171 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 16719171 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 2067212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2067212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2067212 — Safety Biomarker (SAF): Interleukin 1
Study 26822613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26822613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22280514 — Surrogate Endpoint (SUR): Blood pressure
Study 9291 — Surrogate Endpoint (SUR): Blood pressure
Study 30616461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29798418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29798418 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 21649812 — Surrogate Endpoint (SUR): Blood pressure
Study 11157688 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23390553 — Surrogate Endpoint (SUR): Blood pressure
Study 23740460 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study 23740460 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 23740460 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 23740460 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 8810653 — Surrogate Endpoint (SUR): Blood pressure
Study 25311296 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25311296 — Predictive Biomarker (PRD): Hormone receptor
Study 25311296 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15963128 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 20418657 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 18380554 — Predictive Biomarker (PRD): RGR mRNA
Genes: RGR
Study 18380554 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 10227010 — Surrogate Endpoint (SUR): Bone mineral density
Study 7075640 — Surrogate Endpoint (SUR): Blood pressure
Study 19657698 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15837446 — Surrogate Endpoint (SUR): Blood pressure
Study 12203856 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12203856 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9657561 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 16453054 — Surrogate Endpoint (SUR): Blood pressure
Study 15112279 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11665788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 4936366 — Predictive Biomarker (PRD): CPA6 mRNA
Genes: CPA6; CPAH
Study 23863876 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 14506952 — Surrogate Endpoint (SUR): Bone mineral density
Study 8682134 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24736679 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11888840 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11888840 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7661937 — Surrogate Endpoint (SUR): Blood pressure
Study 3047333 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 3047333 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 3047333 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 16221219 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 12148101 — Surrogate Endpoint (SUR): Serum sodium
Study 12148101 — Surrogate Endpoint (SUR): Blood pressure
Study 22094911 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22094911 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21050476 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17577218 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15037444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15037444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1927862 — Surrogate Endpoint (SUR): Blood pressure
Study 7037030 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22642740 — Surrogate Endpoint (SUR): Blood pressure
Study 22642740 — Surrogate Endpoint (SUR): Serum creatinine
Study 30572436 — Surrogate Endpoint (SUR): Blood pressure
Study 24944249 — Surrogate Endpoint (SUR): Blood pressure
Study 22067384 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 20150021 — Surrogate Endpoint (SUR): Blood pressure
Study 6146390 — Surrogate Endpoint (SUR): Blood pressure
Study 18340565 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 24518078 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22281165 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 22281165 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 17099077 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12039122 — Safety Biomarker (SAF): MTHFR
Study 11088064 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8803300 — Surrogate Endpoint (SUR): Blood pressure
Study 1385827 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6364896 — Predictive Biomarker (PRD): CDCA4 mRNA
Genes: CDCA4; HEPP
Study 29807945 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26655888 — Surrogate Endpoint (SUR): Bone mineral density