TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04094740 — Surrogate Endpoint (SUR): Serum hemoglobin A1C
Study NCT02292576 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study NCT03442569 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03442569 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT03588650 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01959490 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03691688 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02380274 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT00798005 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06001671 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03684889 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03068949 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03527654 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT02600117 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01010035 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02593344 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02371993 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT02409940 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03541603 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04596124 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03080376 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03180528 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study NCT00170339 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00784030 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study NCT00561171 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00513617 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01586156 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01586156 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01925105 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT02632175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04241133 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00151216 — Predictive Biomarker (PRD): Tripeptidyl-peptidase I
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study NCT03312738 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03312738 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03289455 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03289455 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT02087917 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03710902 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01723150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03988101 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03988101 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02919085 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT02614833 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01665651 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03774108 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04177160 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00003746 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study NCT00943059 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00263887 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT04083183 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT02156154 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00994435 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03474809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03474809 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01090817 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03791034 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00493779 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT00493779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00668447 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03057457 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03492658 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03468153 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03468153 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT02449655 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02449655 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02449655 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00605878 — Predictive Biomarker (PRD): DOCK8 mRNA
Genes: DOCK8
Study NCT01920984 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01557582 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02995993 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT03885947 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT04292015 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00854997 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT00854997 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study NCT02221479 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01035476 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT01225055 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03808740 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04439188 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT00400582 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00400582 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00754494 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00754494 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01734135 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04507867 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03998709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01230034 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03289338 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT03289338 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT02466802 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01805635 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02555566 — Predictive Biomarker (PRD): EPHX2 mRNA
Genes: EPHX2
Study NCT03016741 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03841708 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03105336 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02620150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02620150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03664843 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01042626 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01042626 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT01869166 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02953730 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00088387 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02400476 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00615524 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00001952 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02905162 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04222491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT02756637 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT01188317 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03968926 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02270216 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01478828 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT02270749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02710591 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03118752 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT04415268 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02339415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04231487 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT02370160 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03993327 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00002589 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02225106 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT04214860 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02857764 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02914769 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02914769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02914769 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT00194792 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00606138 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02536469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01350934 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00446706 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01954940 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02143817 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00914121 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study NCT00698087 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT03747653 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT01014234 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01014234 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00139438 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02507817 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study NCT02507817 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study NCT02507817 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02507817 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study NCT00607035 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01736787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01736787 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00682552 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00743210 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01551147 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study NCT03242785 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00108082 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00108082 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04209777 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04509999 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT02593487 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00002616 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00002616 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01712815 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT00510315 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02266082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04734834 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04412057 — Predictive Biomarker (PRD): TNFSF14 mRNA
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study NCT04412057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01562899 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02133508 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04322357 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03287765 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04663204 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01856439 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study NCT02427984 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study NCT00168207 — Predictive Biomarker (PRD): IL7 mRNA
Genes: IL7
Study NCT01718171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01338714 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT00146341 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00373425 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00471991 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03129932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03042468 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04308720 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03645382 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03396874 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01684215 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT01684215 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01684215 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00977431 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00977431 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00977431 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00338130 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT04486664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04486664 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04486664 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00908219 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00908219 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01337765 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01337765 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT01337765 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01337765 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01337765 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT02343354 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00730951 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02235584 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02408445 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT01182662 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01592721 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00000150 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03659084 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study NCT01178164 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT03718117 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03718117 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT02585869 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04424966 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT04424966 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT04424966 — Predictive Biomarker (PRD): TACC3 mRNA
Genes: TACC3; ERIC1
Study NCT05049837 — Predictive Biomarker (PRD): RHOH mRNA
Genes: RHOH; ARHH; TTF
Study NCT01123577 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02985619 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02985619 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03309917 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06711068 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04123756 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT01794819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00706316 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT01558934 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02648724 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02556593 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00811369 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01846949 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT02883517 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00739973 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01963871 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT03794739 — Predictive Biomarker (PRD): TMEM219 mRNA
Genes: TMEM219
Study NCT00613587 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT02510261 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT01939860 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05647187 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT00173186 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03185182 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT00137657 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03541135 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02745106 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03955939 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03955939 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT03514368 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT00003330 — Safety Biomarker (SAF): Interleukin 12
Study NCT00631449 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00992563 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01082887 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02342912 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01431443 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02603913 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04574245 — Predictive Biomarker (PRD): GCLM mRNA
Genes: GCLM; GLCLR
Study NCT00408668 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study NCT02548572 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study NCT00111761 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02910414 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04191824 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study NCT04191824 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02443324 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study NCT02426099 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02426099 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02426099 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01218802 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02123381 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02123381 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02123381 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03550534 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828