TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25537365 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 25539648 — Surrogate Endpoint (SUR): Serum creatinine
Study 19005973 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12514410 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12514410 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10378564 — Surrogate Endpoint (SUR): Serum creatinine
Study 26860492 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 26860492 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 23782457 — Surrogate Endpoint (SUR): Blood pressure
Study 16309958 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 25428762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20580422 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18211120 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26330303 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17561977 — Surrogate Endpoint (SUR): Bone mineral density
Study 23810691 — Surrogate Endpoint (SUR): Blood pressure
Study 20946227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20946227 — Safety Biomarker (SAF): Reactive oxygen species
Study 20946227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20946227 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 20946227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17645482 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9812649 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17563161 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 2590918 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 25062713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25062713 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25062713 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21144516 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21144516 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15486358 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 23790592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22653043 — Surrogate Endpoint (SUR): Serum creatinine
Study 23579816 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21336108 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27320058 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27320058 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23598289 — Surrogate Endpoint (SUR): Blood pressure
Study 17405870 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17405870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17405870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8466733 — Surrogate Endpoint (SUR): Blood pressure
Study 11878685 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 363480 — Surrogate Endpoint (SUR): Blood pressure
Study 18835660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18835660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11581201 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 24093862 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18464882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11368289 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 11368289 — Surrogate Endpoint (SUR): Bone mineral density
Study 28900123 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 16675577 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11223435 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11223435 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8941054 — Surrogate Endpoint (SUR): Bone mineral density
Study 8941054 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16136167 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 29266398 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29266398 — Surrogate Endpoint (SUR): Serum creatinine
Study 18567824 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 27825977 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 7435247 — Surrogate Endpoint (SUR): Blood pressure
Study 27681944 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27681944 — Safety Biomarker (SAF): Epiregulin
Genes: EREG
Study 24933340 — Surrogate Endpoint (SUR): Blood pressure
Study 23543346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23543346 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19508464 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19508464 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19508464 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 985067 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28715503 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 26168823 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 23883691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12552190 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29851819 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 25261340 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 25261340 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 7373 — Surrogate Endpoint (SUR): Blood pressure
Study 31568009 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 28338229 — Surrogate Endpoint (SUR): Blood pressure
Study 18637615 — Surrogate Endpoint (SUR): Blood pressure
Study 17060763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17060763 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17060763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7523776 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7523776 — Surrogate Endpoint (SUR): Blood pressure
Study 7523776 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20929988 — Surrogate Endpoint (SUR): Blood pressure
Study 18812476 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 14760437 — Surrogate Endpoint (SUR): Blood pressure
Study 9186882 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study 9186882 — Surrogate Endpoint (SUR): Blood pressure
Study 8255512 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8255512 — Surrogate Endpoint (SUR): Blood pressure
Study 3545685 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 27745551 — Surrogate Endpoint (SUR): Blood pressure
Study 27745551 — Surrogate Endpoint (SUR): Serum creatinine
Study 24652467 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 2137218 — Surrogate Endpoint (SUR): Blood pressure
Study 30637626 — Predictive Biomarker (PRD): TRPV4 mRNA
Genes: TRPV4; VRL2; VROAC
Study 22971278 — Monitoring Biomarker (MOI): HBV DNA
Study 27238752 — Monitoring Biomarker (MOI): HBV DNA
Study 21076630 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21076630 — Surrogate Endpoint (SUR): Blood pressure
Study 21076630 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21076630 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10333775 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1758526 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 20448126 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20448126 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 20448126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20448126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20448126 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20448126 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15593387 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 12805079 — Surrogate Endpoint (SUR): Blood pressure
Study 10536648 — Surrogate Endpoint (SUR): Bone mineral density
Study 6120945 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 6120945 — Surrogate Endpoint (SUR): Blood pressure
Study 30694715 — Predictive Biomarker (PRD): TGFB2 mRNA
Genes: TGFB2
Study 30694715 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 30694715 — Predictive Biomarker (PRD): PDE11A mRNA
Genes: PDE11A
Study 30694715 — Predictive Biomarker (PRD): NEGR1 mRNA
Genes: NEGR1; IGLON4; UNQ2433/PRO4993
Study 30694715 — Predictive Biomarker (PRD): CADM2 mRNA
Genes: CADM2; IGSF4D; NECL3
Study 30694715 — Predictive Biomarker (PRD): PCDH7 mRNA
Genes: PCDH7; BHPCDH
Study 30694715 — Predictive Biomarker (PRD): RETREG1 mRNA
Genes: RETREG1; FAM134B; JK1
Study 30694715 — Predictive Biomarker (PRD): DACT2 mRNA
Genes: DACT2; C6orf116; PP13671
Study 30694715 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 25965846 — Predictive Biomarker (PRD): FER mRNA
Genes: FER; TYK3
Study 23812622 — Surrogate Endpoint (SUR): Blood pressure
Study 8562146 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 2698941 — Surrogate Endpoint (SUR): Blood pressure
Study 25630040 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21525253 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16699970 — Surrogate Endpoint (SUR): Blood pressure
Study 27965306 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27965306 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25387312 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 25387312 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23276806 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21621992 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8656503 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8656503 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31834128 — Surrogate Endpoint (SUR): Blood pressure
Study 25779222 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15784639 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 7607973 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 24217684 — Surrogate Endpoint (SUR): Blood pressure
Study 18630561 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 20553629 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 16118787 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 17105777 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17105777 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 17105777 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 17105777 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17105777 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 26957279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26957279 — Surrogate Endpoint (SUR): Serum creatinine
Study 26957279 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24145083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24145083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18313521 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16550749 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 14967827 — Surrogate Endpoint (SUR): Blood pressure
Study 29891745 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29891745 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18191684 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 6379305 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26892128 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26892128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26892128 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19709693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19709693 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19709693 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17381714 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 12110412 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12110412 — Surrogate Endpoint (SUR): Bone mineral density
Study 11011336 — Surrogate Endpoint (SUR): Blood pressure
Study 29783863 — Surrogate Endpoint (SUR): Blood pressure
Study 28689624 — Surrogate Endpoint (SUR): Blood pressure
Study 25600421 — Surrogate Endpoint (SUR): Blood pressure
Study 21975206 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 17137405 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9310603 — Surrogate Endpoint (SUR): Blood pressure
Study 30041929 — Predictive Biomarker (PRD): ALK
Genes: CD246; ALK1
Study 23522096 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 21364273 — Surrogate Endpoint (SUR): Bone mineral density
Study 11684941 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31115304 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 26530491 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 18840576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18840576 — Surrogate Endpoint (SUR): Blood pressure
Study 24526178 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 8781634 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 29788075 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22441644 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9879606 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 2481532 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 810198 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 28549430 — Safety Biomarker (SAF): Hyaluronic acid
Study 10754455 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 8862229 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 22924248 — Surrogate Endpoint (SUR): Blood pressure
Study 10860190 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10860190 — Surrogate Endpoint (SUR): Blood pressure
Study 8470417 — Surrogate Endpoint (SUR): Blood pressure
Study 20117244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24552979 — Surrogate Endpoint (SUR): Bone mineral density
Study 17255295 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8276554 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27592487 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9523374 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21804130 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 21945448 — Predictive Biomarker (PRD): XG mRNA
Genes: XG; PBDX
Study 21945448 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 21945448 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 21945448 — Predictive Biomarker (PRD): TRIP10 mRNA
Genes: TRIP10; CIP4; STOT; STP
Study 8724108 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 8724108 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8724108 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2416412 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2416412 — Surrogate Endpoint (SUR): Blood pressure
Study 9164914 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27578313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23865696 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 16652426 — Safety Biomarker (SAF): Hyaluronic acid
Study 12796754 — Surrogate Endpoint (SUR): Blood pressure
Study 8943183 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30842540 — Surrogate Endpoint (SUR): Blood pressure
Study 27176461 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27176461 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26545456 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26545456 — Safety Biomarker (SAF): BDNF
Study 26545456 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16380390 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8970411 — Surrogate Endpoint (SUR): Blood pressure
Study 16847538 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27185725 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27185725 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 24376009 — Surrogate Endpoint (SUR): Blood pressure
Study 14672887 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 11137832 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9439404 — Surrogate Endpoint (SUR): Serum sodium
Study 8339624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23000125 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 19393843 — Surrogate Endpoint (SUR): Blood pressure
Study 17613395 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 15135473 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 21608223 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21608223 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23412078 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 23412078 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 17081363 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22202581 — Predictive Biomarker (PRD): PAX3 mRNA
Genes: PAX3; HUP2
Study 20860537 — Surrogate Endpoint (SUR): Blood pressure
Study 3891617 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24127698 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24127698 — Safety Biomarker (SAF): BDNF
Study 10608477 — Surrogate Endpoint (SUR): Blood pressure
Study 16990664 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 9483483 — Predictive Biomarker (PRD): PHC3 mRNA
Genes: PHC3; EDR3; PH3
Study 25882743 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 21643812 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 21643812 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21643812 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9356540 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9356540 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26706023 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26706023 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16735113 — Surrogate Endpoint (SUR): Bone mineral density
Study 8705152 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 8705152 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8705152 — Surrogate Endpoint (SUR): Blood pressure
Study 7033016 — Surrogate Endpoint (SUR): Serum uric acid
Study 31658725 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 29202732 — Surrogate Endpoint (SUR): Bone mineral density
Study 21538380 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 7798537 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31237335 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 28287751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8864328 — Surrogate Endpoint (SUR): Blood pressure
Study 24458439 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B