TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00494611 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02813551 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01447628 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01152424 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01788163 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01788163 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00855062 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04720573 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT01774721 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01774721 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02444364 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01799070 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03326076 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02494583 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00797316 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01829178 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT01829178 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01829178 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01829178 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00692107 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT04435509 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01600170 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT00005346 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03713736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03713736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04018755 — Safety Biomarker (SAF): Interleukin 1
Study NCT01025726 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03126591 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT04734028 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT01114399 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04233697 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02228291 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03223428 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT01332279 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00586404 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study NCT01393821 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03431402 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study NCT03431402 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT00244595 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03949270 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01875809 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00264186 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00264186 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT02948127 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02445586 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02445586 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04042064 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT04257110 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03096288 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01795677 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT03322696 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03322696 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT00702221 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00025181 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT00435838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study NCT02972437 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT01530984 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01530984 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02461758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02461758 — Surrogate Endpoint (SUR): Serum antibody concentration
Study NCT03969121 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01833884 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study NCT01833884 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study NCT00886600 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03330847 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03330847 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study NCT02789956 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00424684 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02000440 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01798849 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00117676 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01119300 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01119300 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT02343172 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT03741829 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT03741829 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study NCT02452840 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02008682 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03607890 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT04351581 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04351581 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00065793 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00685503 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00685503 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02795780 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00011323 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00265538 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02401828 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03872440 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00310206 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02394873 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02394873 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT02394873 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01881464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03152019 — Predictive Biomarker (PRD): ALK
Genes: CD246; ALK1
Study NCT03534635 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02559791 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT02559791 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02559791 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00654875 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01054716 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT02964689 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03549182 — Predictive Biomarker (PRD): TPH2 mRNA
Genes: TPH2; NTPH
Study NCT01198496 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02611856 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03064737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04194255 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT02812277 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03545958 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03545958 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02681237 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02681237 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04257162 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02120105 — Surrogate Endpoint (SUR): Urinary cystine
Study NCT01513811 — Safety Biomarker (SAF): DRD2
Study NCT00881439 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00881439 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02018731 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT02663752 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study NCT03841539 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04187768 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04187768 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02835287 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01845090 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04121247 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04665830 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01612715 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00003398 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01258504 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01258504 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT03200886 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03885128 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study NCT01600872 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02267590 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01050309 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study NCT04098770 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01274273 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02586675 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02586675 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03108313 — Surrogate Endpoint (SUR): Bacterial count
Study NCT01741792 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00879229 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT01069822 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01760668 — Predictive Biomarker (PRD): SH3PXD2A mRNA
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study NCT00762892 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00843037 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT04584580 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01773109 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT00665457 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT05736900 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT05736900 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02920346 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study NCT02237209 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02651415 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04148638 — Predictive Biomarker (PRD): NLRP7 mRNA
Genes: NLRP7; NALP7; NOD12; PYPAF3
Study NCT01050296 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01050296 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01059552 — Predictive Biomarker (PRD): HDAC1 mRNA
Genes: HDAC1; RPD3L1
Study NCT01433237 — Safety Biomarker (SAF): miR-206
Genes: MIR206
Study NCT03426085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03426085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03426085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03346811 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02848378 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT00320450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00241124 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03187886 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01877356 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03923543 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT03320616 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT03980054 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03980054 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02756559 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study NCT02756559 — Safety Biomarker (SAF): miR-15a
Genes: MIR15A
Study NCT02756559 — Safety Biomarker (SAF): miR-16
Study NCT02134002 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study NCT01601236 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00535639 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02066181 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study NCT04472286 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01453218 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT01239602 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02738983 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02738983 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06702540 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01991340 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03500900 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01560663 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study NCT01560663 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01560663 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01560663 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00019539 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03649646 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00478543 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04433884 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00984217 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00984217 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02909400 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04798573 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study NCT04798573 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study NCT03430648 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02753595 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02753595 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03857490 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00418236 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03949283 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT04365595 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01744977 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01830504 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01830504 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT01830504 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03356834 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04288141 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04288141 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT04288141 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study NCT03944798 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT02115048 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02118818 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT00005072 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00004941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02543229 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02543229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00492882 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02664935 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT01435382 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00416910 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02215356 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02068495 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01245946 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT03620227 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03491631 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT04963556 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01201135 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study NCT02177032 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01054989 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01979471 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03051360 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04356560 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03043248 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT03043248 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02510027 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02510027 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01727219 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT00897234 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study NCT01277549 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01277549 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02868632 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT00002879 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study NCT02175524 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02175524 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02175524 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02175524 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT02175524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02175524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02175524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01752153 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01752153 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT05979298 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study NCT04346212 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00999804 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00999804 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00999804 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03495388 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1