TrialPanorama/TrialPanorama-database huggingface dataset:
Study 14623801 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 1424413 — Surrogate Endpoint (SUR): Serum testosterone
Study 11420782 — Surrogate Endpoint (SUR): Bone mineral density
Study 27287612 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 12875347 — Surrogate Endpoint (SUR): Blood pressure
Study 8753675 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 6798903 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30508141 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8588407 — Surrogate Endpoint (SUR): Blood pressure
Study 18946484 — Surrogate Endpoint (SUR): Blood pressure
Study 17467226 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 15711683 — Surrogate Endpoint (SUR): Blood pressure
Study 28394819 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 10335757 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26489809 — Surrogate Endpoint (SUR): Blood pressure
Study 26489809 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16053212 — Surrogate Endpoint (SUR): Blood pressure
Study 11954883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11954883 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 1534312 — Surrogate Endpoint (SUR): Blood pressure
Study 28151883 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28151883 — Surrogate Endpoint (SUR): Bone mineral density
Study 25985907 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23729226 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19951408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3002672 — Surrogate Endpoint (SUR): Blood pressure
Study 22678699 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 15664001 — Surrogate Endpoint (SUR): Bone mineral density
Study 11799482 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22014374 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22662394 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 20837359 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20837359 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 16626422 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 10967266 — Surrogate Endpoint (SUR): Bone mineral density
Study 7949627 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9118614 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6465021 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6465021 — Surrogate Endpoint (SUR): Blood pressure
Study 31690602 — Surrogate Endpoint (SUR): Bone mineral density
Study 28743399 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28743399 — Surrogate Endpoint (SUR): Blood pressure
Study 23403498 — Surrogate Endpoint (SUR): Bone mineral density
Study 21788220 — Surrogate Endpoint (SUR): Blood pressure
Study 31475597 — Surrogate Endpoint (SUR): Blood pressure
Study 25678778 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11297592 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 2949907 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 19771504 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28547861 — Surrogate Endpoint (SUR): Blood pressure
Study 26062186 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9640413 — Surrogate Endpoint (SUR): Bone mineral density
Study 10784629 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 8867559 — Surrogate Endpoint (SUR): Blood pressure
Study 22883540 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18544744 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12794406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27619983 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 12628949 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10776077 — Surrogate Endpoint (SUR): Blood pressure
Study 31766063 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 23392460 — Surrogate Endpoint (SUR): Serum creatinine
Study 14997022 — Surrogate Endpoint (SUR): Bone mineral density
Study 31376153 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 25436819 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22293059 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19797501 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15831351 — Surrogate Endpoint (SUR): Blood pressure
Study 8622099 — Surrogate Endpoint (SUR): Serum creatinine
Study 31699517 — Surrogate Endpoint (SUR): Bone mineral density
Study 31699517 — Surrogate Endpoint (SUR): Serum potassium
Study 31699517 — Surrogate Endpoint (SUR): Blood pressure
Study 29306619 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29306619 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29306619 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23937849 — Surrogate Endpoint (SUR): Blood pressure
Study 23937849 — Surrogate Endpoint (SUR): Serum creatinine
Study 20065611 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23098346 — Surrogate Endpoint (SUR): Blood pressure
Study 1541318 — Surrogate Endpoint (SUR): Blood pressure
Study 1541318 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1541318 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27377404 — Surrogate Endpoint (SUR): Blood pressure
Study 19318448 — Surrogate Endpoint (SUR): Blood pressure
Study 19318448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19318448 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19318448 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23117243 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21402164 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 15635596 — Surrogate Endpoint (SUR): Pathological complete response
Study 8124953 — Safety Biomarker (SAF): Interleukin 1
Study 8124953 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31735538 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 10579482 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 7574017 — Surrogate Endpoint (SUR): Blood pressure
Study 6271841 — Surrogate Endpoint (SUR): Blood pressure
Study 31164169 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 22762143 — Monitoring Biomarker (MOI): HBV DNA
Study 12115174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12115174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7720497 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 2557513 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 336378 — Surrogate Endpoint (SUR): Blood pressure
Study 22845044 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8701411 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8701411 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1906532 — Surrogate Endpoint (SUR): Serum calcium
Study 1906532 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29523089 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 24754911 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24754911 — Surrogate Endpoint (SUR): Blood pressure
Study 20455879 — Surrogate Endpoint (SUR): Blood pressure
Study 12540388 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 12540388 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 31897661 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 22929242 — Surrogate Endpoint (SUR): Blood pressure
Study 20813339 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 7562882 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20205331 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24673048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24673048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11889009 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 10461554 — Surrogate Endpoint (SUR): Blood pressure
Study 25831269 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1004355 — Surrogate Endpoint (SUR): Blood pressure
Study 12575571 — Predictive Biomarker (PRD): AHSP mRNA
Genes: AHSP; EDRF; ERAF
Study 12575571 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9847433 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31469027 — Surrogate Endpoint (SUR): Serum uric acid
Study 24074707 — Monitoring Biomarker (MOI): HBV DNA
Study 21877028 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 16319906 — Surrogate Endpoint (SUR): Blood pressure
Study 11014757 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11014757 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 1343270 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31729087 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31729087 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 31729087 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 30665436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31280410 — Surrogate Endpoint (SUR): Serum sodium
Study 2877127 — Surrogate Endpoint (SUR): Blood pressure
Study 18949838 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 15986443 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 26813468 — Surrogate Endpoint (SUR): Blood pressure
Study 12804729 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6423720 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 6423720 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 6423720 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 6409009 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 30761568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30761568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24162898 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24162898 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20554627 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 20554627 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 20554627 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 10505301 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30632140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11394392 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 31240435 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23646465 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 18377970 — Surrogate Endpoint (SUR): Blood pressure
Study 18377970 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18377970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24764585 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 24764585 — Predictive Biomarker (PRD): SFRP2 mRNA
Genes: SFRP2; FRP2; SARP1; FKSG12; UNQ361/PRO697
Study 24764585 — Predictive Biomarker (PRD): WIF1 mRNA
Genes: WIF1; UNQ191/PRO217
Study 7698516 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7698516 — Surrogate Endpoint (SUR): Blood pressure
Study 665535 — Surrogate Endpoint (SUR): Blood pressure
Study 20740615 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18071252 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 1696577 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 17377586 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10452746 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2189591 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 27984230 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 26216675 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 26216675 — Safety Biomarker (SAF): Reactive oxygen species
Study 26216675 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 26216675 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 24036568 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 16476934 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 12627850 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10784622 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10784622 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8980158 — Surrogate Endpoint (SUR): Blood pressure
Study 1459878 — Surrogate Endpoint (SUR): Blood pressure
Study 30238430 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 28513635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3316304 — Surrogate Endpoint (SUR): Blood pressure
Study 28668998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21086021 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 21086021 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 21086021 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11084130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11084130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27687452 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20683333 — Surrogate Endpoint (SUR): Blood pressure
Study 2939214 — Surrogate Endpoint (SUR): Blood pressure
Study 20179229 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20179229 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12502669 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1283117 — Surrogate Endpoint (SUR): Bone mineral density
Study 1283117 — Surrogate Endpoint (SUR): Serum calcium
Study 1283117 — Surrogate Endpoint (SUR): Serum testosterone
Study 31840323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26899523 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 26899523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15943846 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 14598618 — Surrogate Endpoint (SUR): Blood pressure
Study 10807895 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 8799657 — Surrogate Endpoint (SUR): Blood pressure
Study 28946539 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29436854 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 21114656 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 9780281 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31666651 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31666651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31666651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31666651 — Safety Biomarker (SAF): BDNF
Study 31666651 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19568027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14722627 — Surrogate Endpoint (SUR): Bone mineral density
Study 17585023 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14566492 — Surrogate Endpoint (SUR): Blood pressure
Study 2154086 — Surrogate Endpoint (SUR): Blood pressure
Study 2154086 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31582554 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 27465911 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27465911 — Surrogate Endpoint (SUR): Blood pressure
Study 7930727 — Predictive Biomarker (PRD): FCGR2A
Genes: CD32; CD32A; IGFR2; CDw32; Fc-gamma-RIIa; FcgammaRIIa
Study 3294594 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3294594 — Surrogate Endpoint (SUR): Blood pressure
Study 30354904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27366817 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 25846344 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 15219658 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15219658 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21451140 — Surrogate Endpoint (SUR): Blood pressure
Study 10638377 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10638377 — Surrogate Endpoint (SUR): Plasma ammonia
Study 31789482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31789482 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31789482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24929431 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study 17434847 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28408243 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 8989424 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21102998 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 18203893 — Surrogate Endpoint (SUR): Blood pressure
Study 10999156 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25563677 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24247275 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24247275 — Surrogate Endpoint (SUR): Blood pressure
Study 24247275 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15187573 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15187573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10489384 — Surrogate Endpoint (SUR): Blood pressure
Study 17337887 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15485475 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15485475 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9623632 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 9623632 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9623632 — Surrogate Endpoint (SUR): Plasma ammonia
Study 24003041 — Surrogate Endpoint (SUR): Blood pressure
Study 21410294 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21410294 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 21410294 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21410294 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12511526 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30653843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17679559 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 2742942 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 810265 — Surrogate Endpoint (SUR): Blood pressure
Study 29223557 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27769209 — Surrogate Endpoint (SUR): Blood pressure
Study 20133499 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20133499 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 12641541 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27296663 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 25148255 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 25148255 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 25148255 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2