TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31661606 — Predictive Biomarker (PRD): GKN1 mRNA
Genes: GKN1; AMP18; CA11; UNQ489/PRO1005
Study 31661606 — Predictive Biomarker (PRD): B3GNT3 mRNA
Genes: B3GNT3; B3GALT8; TMEM3; UNQ637/PRO1266
Study 31661606 — Predictive Biomarker (PRD): FUT2 mRNA
Genes: FUT2; SEC2
Study 21088546 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16284232 — Surrogate Endpoint (SUR): Blood pressure
Study 9166392 — Surrogate Endpoint (SUR): Bone mineral density
Study 20458613 — Surrogate Endpoint (SUR): Blood pressure
Study 18262771 — Surrogate Endpoint (SUR): Blood pressure
Study 14673757 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1650315 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 10634646 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10634646 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21358504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21358504 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10708160 — Surrogate Endpoint (SUR): Blood pressure
Study 31302685 — Surrogate Endpoint (SUR): Bone mineral density
Study 31302685 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27699485 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 27699485 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20080201 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10740401 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 10740401 — Predictive Biomarker (PRD): RAB11FIP1 mRNA
Genes: RAB11FIP1; RCP
Study 10740401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17511246 — Surrogate Endpoint (SUR): Blood pressure
Study 26372387 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2760359 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20820795 — Surrogate Endpoint (SUR): Blood pressure
Study 11437888 — Surrogate Endpoint (SUR): Blood pressure
Study 9710890 — Safety Biomarker (SAF): Interleukin 1
Study 3428378 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29778486 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 26867075 — Surrogate Endpoint (SUR): Blood pressure
Study 24726294 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 25424951 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 14672298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11204322 — Monitoring Biomarker (MOI): Procalcitonin
Study 8611684 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 28967235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27565651 — Predictive Biomarker (PRD): CHRNA7 mRNA
Genes: CHRNA7; NACHRA7
Study 20525995 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 20525995 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 30951193 — Predictive Biomarker (PRD): ALK
Genes: CD246; ALK1
Study 20512335 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 14767810 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 23926329 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 20193095 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20193095 — Surrogate Endpoint (SUR): Bone mineral density
Study 12402423 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12402423 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24832980 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Growth/differentiation factor 8
Genes: MSTN; GDF8
Study 18813866 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7594026 — Surrogate Endpoint (SUR): Blood pressure
Study 26081587 — Surrogate Endpoint (SUR): Blood pressure
Study 23832086 — Monitoring Biomarker (MOI): HBV DNA
Study 10877005 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10877005 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8810671 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 22130178 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 10752808 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 22879421 — Predictive Biomarker (PRD): ETV5 mRNA
Genes: ETV5; ERM
Study 12860216 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12860216 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9125301 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9125301 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31832291 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 19013573 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23858718 — Predictive Biomarker (PRD): NOD2 mRNA
Genes: NOD2; CARD15; IBD1
Study 11498212 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9862014 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30422909 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 25930115 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9515594 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18070940 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12701865 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 30952572 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30952572 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 30952572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30952572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30952572 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16790698 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2983304 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28786012 — Predictive Biomarker (PRD): HPX mRNA
Genes: HPX
Study 28786012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26621366 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 16044340 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7781143 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11696050 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9130894 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20131031 — Monitoring Biomarker (MOI): HBV DNA
Study 20131031 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20131031 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11317832 — Surrogate Endpoint (SUR): Blood pressure
Study 25127240 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 15841891 — Surrogate Endpoint (SUR): Bone mineral density
Study 7064879 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15037872 — Surrogate Endpoint (SUR): Blood pressure
Study 9658723 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 2562912 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27979820 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 16330291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8137477 — Predictive Biomarker (PRD): SMARCA2 mRNA
Genes: SMARCA2; BAF190B; BRM; SNF2A; SNF2L2
Study 2737799 — Surrogate Endpoint (SUR): Blood pressure
Study 21457214 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 19587362 — Surrogate Endpoint (SUR): Blood pressure
Study 16999946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9796243 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 29196578 — Predictive Biomarker (PRD): KCNT1 mRNA
Genes: KCNT1; KIAA1422
Study 22540883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22540883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11408327 — Predictive Biomarker (PRD): CA4 mRNA
Genes: CA4
Study 11408327 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 11408327 — Predictive Biomarker (PRD): CA3 mRNA
Genes: CA3
Study 29845932 — Surrogate Endpoint (SUR): Blood pressure
Study 27918443 — Predictive Biomarker (PRD); Safety Biomarker (SAF): EGR1 mRNA
Genes: EGR1; KROX24; ZNF225
Study 27918443 — Predictive Biomarker (PRD): ID3 mRNA
Genes: ID3; 1R21; BHLHB25; HEIR1
Study 22648709 — Surrogate Endpoint (SUR): Blood pressure
Study 22648709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20697939 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 20697939 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 17996436 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15941145 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10577446 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20214328 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 20214328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22782607 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 15450783 — Predictive Biomarker (PRD): NDUFV2 mRNA
Genes: NDUFV2
Study 18800453 — Surrogate Endpoint (SUR): Blood pressure
Study 17372316 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11240973 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 11240973 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 7755478 — Surrogate Endpoint (SUR): Blood pressure
Study 23138352 — Surrogate Endpoint (SUR): Bone mineral density
Study 16855451 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 6307458 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25243325 — Monitoring Biomarker (MOI): HBV DNA
Study 6094995 — Surrogate Endpoint (SUR): Blood pressure
Study 25487682 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 15271731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8513525 — Surrogate Endpoint (SUR): Blood pressure
Study 17688420 — Surrogate Endpoint (SUR): Serum creatinine
Study 17688420 — Surrogate Endpoint (SUR): Blood pressure
Study 1838032 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30155949 — Surrogate Endpoint (SUR): Pathological complete response
Study 22571408 — Surrogate Endpoint (SUR): Bone mineral density
Study 19140508 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 12423628 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7537524 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7537524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2095747 — Surrogate Endpoint (SUR): Blood pressure
Study 9394977 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 9394977 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16705315 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26304789 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 26304789 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 15944533 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 8739021 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29897597 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 19350305 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 11345493 — Predictive Biomarker (PRD): VTN mRNA
Genes: VTN
Study 11345493 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8314485 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29070044 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29070044 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29070044 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9803327 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 7647083 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 7647083 — Surrogate Endpoint (SUR): Blood pressure
Study 30658192 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 29927180 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29927180 — Surrogate Endpoint (SUR): Blood pressure
Study 24105075 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 1598875 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3413273 — Surrogate Endpoint (SUR): Blood pressure
Study 28488192 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28488192 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26193865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2544132 — Surrogate Endpoint (SUR): Blood pressure
Study 27028002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27028002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20183539 — Surrogate Endpoint (SUR): Blood pressure
Study 15459594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15459594 — Surrogate Endpoint (SUR): Serum uric acid
Study 16303616 — Surrogate Endpoint (SUR): Serum creatinine
Study 1119734 — Surrogate Endpoint (SUR): Blood pressure
Study 1822264 — Surrogate Endpoint (SUR): Blood pressure
Study 1822264 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6124653 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29470854 — Surrogate Endpoint (SUR): Bone mineral density
Study 17631786 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 17631786 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 16140229 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 16140229 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31028165 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 28504321 — Surrogate Endpoint (SUR): Blood pressure
Study 15233975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15233975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15233975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15233975 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9237960 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29766325 — Surrogate Endpoint (SUR): Blood pressure
Study 25156780 — Safety Biomarker (SAF): Reactive oxygen species
Study 25156780 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15370682 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 11535316 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9692077 — Surrogate Endpoint (SUR): Bone mineral density
Study 24042479 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 30963443 — Surrogate Endpoint (SUR): Blood pressure
Study 18212034 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18212034 — Surrogate Endpoint (SUR): Blood pressure
Study 27912960 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27912960 — Surrogate Endpoint (SUR): Blood pressure
Study 20545210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12752555 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12752555 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9467046 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 28765681 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28765681 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22174580 — Surrogate Endpoint (SUR): Blood pressure
Study 16543688 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16543688 — Surrogate Endpoint (SUR): Serum creatinine
Study 16543688 — Surrogate Endpoint (SUR): Blood pressure
Study 30440010 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30440010 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30440010 — Surrogate Endpoint (SUR): Blood pressure
Study 18279765 — Predictive Biomarker (PRD): Hormone receptor
Study 19190970 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-143
Genes: MIR143
Study 19190970 — Safety Biomarker (SAF): miR-205
Genes: MIR205
Study 3296668 — Surrogate Endpoint (SUR): Serum potassium
Study 31098739 — Predictive Biomarker (PRD): ZNF471 mRNA
Genes: ZNF471; ERP1; KIAA1396
Study 31098739 — Predictive Biomarker (PRD): THOC5 mRNA
Genes: THOC5; C22orf19; KIAA0983
Study 22650799 — Surrogate Endpoint (SUR): Blood pressure
Study 11100017 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9171252 — Surrogate Endpoint (SUR): Blood pressure
Study 2942753 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 2942753 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 2942753 — Surrogate Endpoint (SUR): Blood pressure
Study 2893527 — Surrogate Endpoint (SUR): Blood pressure
Study 31196847 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 25970511 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 19497447 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19497447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19497447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9024733 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9024733 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8331091 — Surrogate Endpoint (SUR): Blood pressure
Study 24390808 — Surrogate Endpoint (SUR): Bone mineral density
Study 12544908 — Safety Biomarker (SAF): IL-6 and IL-10
Study 6129141 — Surrogate Endpoint (SUR): Blood pressure
Study 29326421 — Surrogate Endpoint (SUR): Blood pressure
Study 29326421 — Surrogate Endpoint (SUR): Serum calcium
Study 9867157 — Surrogate Endpoint (SUR): Serum creatinine
Study 7638802 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 2765808 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 1093756 — Surrogate Endpoint (SUR): Blood pressure
Study 12577187 — Surrogate Endpoint (SUR): Bone mineral density
Study 22657838 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8050544 — Surrogate Endpoint (SUR): Forced vital capacity
Study 342217 — Surrogate Endpoint (SUR): Serum creatinine
Study 30193971 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 23916874 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 14722167 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 9024026 — Surrogate Endpoint (SUR): Blood pressure
Study 2871744 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15925121 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 1726002 — Surrogate Endpoint (SUR): Blood pressure
Study 22159672 — Surrogate Endpoint (SUR): Bone mineral density
Study 21367594 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19411954 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9089939 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 8506440 — Surrogate Endpoint (SUR): Blood pressure
Study 27565012 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 24845208 — Surrogate Endpoint (SUR): Blood pressure
Study 16953457 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29879602 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 20652004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20652004 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17645503 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 26965694 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25318787 — Surrogate Endpoint (SUR): Serum creatinine
Study 22074122 — Surrogate Endpoint (SUR): Blood pressure
Study 12171961 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 12171961 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 12171961 — Predictive Biomarker (PRD): MUC6 mRNA
Genes: MUC6
Study 8508666 — Surrogate Endpoint (SUR): Blood pressure
Study 31812457 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 24404816 — Surrogate Endpoint (SUR): Blood pressure
Study 24404816 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11738120 — Surrogate Endpoint (SUR): Serum calcium
Study 25648379 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25648379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15307695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15307695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1