TrialPanorama/TrialPanorama-database huggingface dataset:
Study 2453895 — Surrogate Endpoint (SUR): Blood pressure
Study 24391139 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20385995 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 20385995 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 20385995 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 20385995 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 20385995 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 2877645 — Surrogate Endpoint (SUR): Blood pressure
Study 31747468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31747468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31747468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30251010 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28081351 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28081351 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12427649 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19401662 — Surrogate Endpoint (SUR): Blood pressure
Study 16963248 — Predictive Biomarker (PRD): Hormone receptor
Study 14508205 — Surrogate Endpoint (SUR): Blood pressure
Study 11025232 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11025232 — Surrogate Endpoint (SUR): Blood pressure
Study 11264758 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2508791 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30476131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19928391 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 12539568 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 8233295 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25575620 — Surrogate Endpoint (SUR): Blood pressure
Study 23168399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23168399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16968913 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 11335737 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8302922 — Surrogate Endpoint (SUR): Blood pressure
Study 26360125 — Surrogate Endpoint (SUR): Serum creatinine
Study 11169027 — Predictive Biomarker (PRD): CES2 mRNA
Genes: CES2; ICE
Study 18050368 — Surrogate Endpoint (SUR): Bone mineral density
Study 10852452 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10852452 — Surrogate Endpoint (SUR): Bone mineral density
Study 8096389 — Surrogate Endpoint (SUR): Blood pressure
Study 27386644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18374003 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 17409936 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 10834668 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15934285 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12468782 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 31696504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19498009 — Predictive Biomarker (PRD): NOCT mRNA
Genes: NOCT; CCR4; CCRN4L; NOC
Study 14660997 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23926117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23926117 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3299443 — Surrogate Endpoint (SUR): Blood pressure
Study 28326881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26804247 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23275013 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 10881824 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29095521 — Surrogate Endpoint (SUR): Serum testosterone
Study 2515593 — Safety Biomarker (SAF): 51Cr-EDTA
Study 27217047 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 17645554 — Surrogate Endpoint (SUR): Blood pressure
Study 26233827 — Surrogate Endpoint (SUR): Blood pressure
Study 24244339 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 24244339 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18347653 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 18347653 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 11040231 — Surrogate Endpoint (SUR): Blood pressure
Study 7927956 — Surrogate Endpoint (SUR): Blood pressure
Study 395129 — Surrogate Endpoint (SUR): Blood pressure
Study 28537001 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 27503566 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 17150023 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 17150023 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15116260 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9557622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2651949 — Surrogate Endpoint (SUR): Serum creatinine
Study 31537327 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 28757104 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 23639514 — Surrogate Endpoint (SUR): Blood pressure
Study 19706631 — Predictive Biomarker (PRD): SPIN1 mRNA
Genes: SPIN1; OCR; SPIN
Study 10933918 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 1330437 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29158011 — Predictive Biomarker (PRD): Hormone receptor
Study 22115190 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 17139601 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 14971794 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 31987228 — Surrogate Endpoint (SUR): Blood pressure
Study 28544610 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 28544610 — Predictive Biomarker (PRD): PON3 mRNA
Genes: PON3
Study 28544610 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24177170 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19352324 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19352324 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9438781 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9438781 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9438781 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26648706 — Surrogate Endpoint (SUR): Serum potassium
Study 21621929 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 1998281 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1998281 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9736437 — Surrogate Endpoint (SUR): Blood pressure
Study 9736437 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9736437 — Surrogate Endpoint (SUR): Serum creatinine
Study 9736437 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8422204 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8422204 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20431394 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 20431394 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28389217 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25731939 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 21788663 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 17126775 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17126775 — Surrogate Endpoint (SUR): Blood pressure
Study 10690882 — Surrogate Endpoint (SUR): Bone mineral density
Study 9350365 — Surrogate Endpoint (SUR): Blood pressure
Study 16359823 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 16359823 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIPOX mRNA
Genes: PIPOX; LPIPOX; PSO
Study 16359823 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9265931 — Surrogate Endpoint (SUR): Blood pressure
Study 8396082 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31045455 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28028730 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 19325186 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16462503 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 11744593 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9734737 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 18096843 — Surrogate Endpoint (SUR): Blood pressure
Study 1516676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31884313 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31884313 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 24297946 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24297946 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 21484793 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12566675 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7815178 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 7073802 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24256483 — Surrogate Endpoint (SUR): Blood pressure
Study 18544145 — Surrogate Endpoint (SUR): Blood pressure
Study 12955684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21627741 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 28693594 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 25294611 — Surrogate Endpoint (SUR): Blood pressure
Study 2136968 — Surrogate Endpoint (SUR): Blood pressure
Study 12418395 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 7791267 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 1942284 — Surrogate Endpoint (SUR): Serum creatinine
Study 27094558 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 16360449 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11465651 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11465651 — Surrogate Endpoint (SUR): Blood pressure
Study 17097957 — Surrogate Endpoint (SUR): Blood pressure
Study 17097957 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17097957 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28514601 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 26289355 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 24121755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24121755 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24121755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24121755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23073140 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12044300 — Monitoring Biomarker (MOI): HBV DNA
Study 10350219 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 8983878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 4076325 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 4076325 — Surrogate Endpoint (SUR): Blood pressure
Study 22446490 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 20811348 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10694618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10694618 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 10694618 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10694618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1476278 — Surrogate Endpoint (SUR): Blood pressure
Study 6097521 — Surrogate Endpoint (SUR): Blood pressure
Study 31246237 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 31246237 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31246237 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29306517 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study 28003221 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24271647 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 15554580 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 9152688 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 20969662 — Safety Biomarker (SAF): Hyaluronic acid
Study 26833223 — Predictive Biomarker (PRD): LMX1A mRNA
Genes: LMX1A
Study 2656340 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 29374054 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29374054 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 19318632 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 16525578 — Safety Biomarker (SAF): Reactive oxygen species
Study 12598488 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10766888 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20676027 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 15866088 — Surrogate Endpoint (SUR): Bone mineral density
Study 9118296 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 11882746 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8907208 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8907208 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29173690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29173690 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21615691 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 16804739 — Surrogate Endpoint (SUR): Bone mineral density
Study 12637702 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 10818061 — Surrogate Endpoint (SUR): Blood pressure
Study 29846435 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29846435 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25312396 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 25312396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 12021625 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 10071518 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1705193 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1705193 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1705193 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28714526 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28714526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20390483 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17634459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17634459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28975998 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28975998 — Predictive Biomarker (PRD): miR-106a
Genes: MIR106A
Study 26341987 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 26341987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10638893 — Surrogate Endpoint (SUR): Blood pressure
Study 9162612 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17592349 — Surrogate Endpoint (SUR): Blood pressure
Study 16298774 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 21719530 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21719530 — Predictive Biomarker (PRD): XPC mRNA
Genes: XPC; XPCC
Study 21719530 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 21719530 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 21719530 — Safety Biomarker (SAF): IL-6 and IL-10
Study 11423055 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9290362 — Safety Biomarker (SAF): Hyaluronic acid
Study 2890806 — Surrogate Endpoint (SUR): Blood pressure
Study 29489078 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 28124381 — Surrogate Endpoint (SUR): Blood pressure
Study 28124381 — Surrogate Endpoint (SUR): Bone mineral density
Study 2000798 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20522536 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 20522536 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 16906395 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16906395 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8658221 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 31415087 — Predictive Biomarker (PRD): TACR3 mRNA
Genes: TACR3; NK3R; TAC3R
Study 10930153 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2436011 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 18433921 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18433921 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 18433921 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 20076952 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9670875 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18464752 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 15894962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15894962 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9346691 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27296819 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24532007 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 15908835 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 10917210 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 3083712 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3083712 — Surrogate Endpoint (SUR): Blood pressure
Study 31698336 — Surrogate Endpoint (SUR): Blood pressure
Study 31608549 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7011163 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 6338889 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20102884 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20102884 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2649300 — Surrogate Endpoint (SUR): Blood pressure
Study 37848 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 10812378 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10812378 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 4006252 — Surrogate Endpoint (SUR): Blood pressure
Study 27907814 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25701561 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24030410 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16556417 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16556417 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 1421063 — Surrogate Endpoint (SUR): Blood pressure
Study 16115394 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12796125 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 12796125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10802126 — Predictive Biomarker (PRD): GRAMD4 mRNA
Genes: GRAMD4; DIP; KIAA0767
Study 26849784 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21753160 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 21753160 — Surrogate Endpoint (SUR): Blood pressure
Study 19210142 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19210142 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 16714386 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10567624 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10567624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10567624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10567624 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8704426 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 8704426 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8704426 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX