TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31439579 — Predictive Biomarker (PRD): Hormone receptor
Study 11348605 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11348605 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11348605 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9517940 — Surrogate Endpoint (SUR): Serum creatinine
Study 22255101 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 16797329 — Surrogate Endpoint (SUR): Bone mineral density
Study 19897063 — Surrogate Endpoint (SUR): Bone mineral density
Study 18414411 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 18414411 — Predictive Biomarker (PRD): RRM2 mRNA
Genes: RRM2; RR2
Study 31772611 — Surrogate Endpoint (SUR): Blood pressure
Study 26068576 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24938526 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12200465 — Monitoring Biomarker (MOI): Cell-free DNA
Study 26226029 — Predictive Biomarker (PRD): PHAX mRNA
Genes: PHAX; RNUXA
Study 26226029 — Surrogate Endpoint (SUR): Blood pressure
Study 19589241 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19589241 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10197085 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20202489 — Surrogate Endpoint (SUR): Blood pressure
Study 4048835 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 28683283 — Predictive Biomarker (PRD): TBK1 mRNA
Genes: TBK1; NAK
Study 21545459 — Surrogate Endpoint (SUR): Blood pressure
Study 19701647 — Surrogate Endpoint (SUR): Blood pressure
Study 27480840 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27480840 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27480840 — Surrogate Endpoint (SUR): Blood pressure
Study 11339912 — Safety Biomarker (SAF): Interleukin 1
Study 11339912 — Surrogate Endpoint (SUR): Blood pressure
Study 3894872 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21518220 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21518220 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21518220 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17068306 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 1442589 — Surrogate Endpoint (SUR): Blood pressure
Study 22593231 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 21195290 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 8669676 — Surrogate Endpoint (SUR): Blood pressure
Study 11533267 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31350540 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31350540 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31350540 — Surrogate Endpoint (SUR): Blood pressure
Study 27164830 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 23677794 — Surrogate Endpoint (SUR): Blood pressure
Study 19953916 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19953916 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 15071125 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 15071125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24223352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 23328189 — Surrogate Endpoint (SUR): Blood pressure
Study 12612157 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10960369 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 25828037 — Safety Biomarker (SAF): Hyaluronic acid
Study 21163921 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21163921 — Predictive Biomarker (PRD): STXBP5 mRNA
Genes: STXBP5; LLGL3
Study 21163921 — Predictive Biomarker (PRD): SCARA5 mRNA
Genes: SCARA5; UNQ2938/PRO28700
Study 21163921 — Predictive Biomarker (PRD): STAB2 mRNA
Genes: STAB2; FEEL2; FELL; FEX2; HARE
Study 21163921 — Predictive Biomarker (PRD): STX2 mRNA
Genes: STX2; EPIM; STX2A; STX2B; STX2C
Study 21163921 — Predictive Biomarker (PRD): TC2N mRNA
Genes: TC2N; C14orf47; MTAC2D1
Study 21163921 — Predictive Biomarker (PRD): CLEC4M mRNA
Genes: CLEC4M; CD209L; CD209L1; CD299
Study 17823443 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 17823443 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 17823443 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 17823443 — Predictive Biomarker (PRD): DGAT2 mRNA
Genes: DGAT2; HMFN1045; UNQ738/PRO1433
Study 11213870 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11213870 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8675565 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 31052277 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 31052277 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31052277 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26115520 — Surrogate Endpoint (SUR): Serum creatinine
Study 23527597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30010081 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 19531688 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15157952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15157952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9591438 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7887824 — Surrogate Endpoint (SUR): Blood pressure
Study 15450049 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 15450049 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15450049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15450049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24022373 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21967830 — Surrogate Endpoint (SUR): Blood pressure
Study 19757980 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19757980 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19757980 — Surrogate Endpoint (SUR): Serum creatinine
Study 3053896 — Surrogate Endpoint (SUR): Blood pressure
Study 24184274 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYL9 mRNA
Genes: MYL9; MLC2; MRLC1; MYRL2
Study 8882904 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 26995372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17494885 — Surrogate Endpoint (SUR): Serum creatinine
Study 16334026 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9935014 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8678248 — Surrogate Endpoint (SUR): Blood pressure
Study 31016887 — Predictive Biomarker (PRD): MYH1 mRNA
Genes: MYH1
Study 31016887 — Predictive Biomarker (PRD): MYH2 mRNA
Genes: MYH2; MYHSA2
Study 31016887 — Predictive Biomarker (PRD): MYH4 mRNA
Genes: MYH4
Study 31016887 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 31016887 — Predictive Biomarker (PRD): TRIM62 mRNA
Genes: TRIM62
Study 31016887 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FBXO32 mRNA
Genes: FBXO32
Study 24989842 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 24989842 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 24989842 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24989842 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 24989842 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24989842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2680866 — Monitoring Biomarker (MOI): HBV DNA
Study 25534960 — Surrogate Endpoint (SUR): Blood pressure
Study 19804594 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 19804594 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16735702 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15556150 — Safety Biomarker (SAF): Reactive oxygen species
Study 9123740 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21733304 — Surrogate Endpoint (SUR): Bone mineral density
Study 18388160 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 30633368 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 30633368 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 30633368 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26274827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23253886 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19786383 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 19786383 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19786383 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19786383 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11773988 — Surrogate Endpoint (SUR): Blood pressure
Study 8139472 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26354678 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15367100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21122851 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21122851 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 17188883 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 17188883 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 9331000 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9331000 — Surrogate Endpoint (SUR): Blood pressure
Study 7503183 — Surrogate Endpoint (SUR): Bone mineral density
Study 2196946 — Surrogate Endpoint (SUR): Blood pressure
Study 21592295 — Surrogate Endpoint (SUR): Blood pressure
Study 18089891 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18285358 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12723743 — Surrogate Endpoint (SUR): Serum creatinine
Study 1662325 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24923232 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 1092276 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 9438978 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8175973 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 2773967 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31408137 — Surrogate Endpoint (SUR): Blood pressure
Study 24367678 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17113831 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17113831 — Surrogate Endpoint (SUR): Blood pressure
Study 24742955 — Surrogate Endpoint (SUR): Bone mineral density
Study 12375668 — Surrogate Endpoint (SUR): Serum potassium
Study 27181565 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23235363 — Surrogate Endpoint (SUR): Blood pressure
Study 12269790 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 10025924 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26306566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26306566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23429675 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9891830 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22044987 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 17197849 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 14747230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14747230 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14747230 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11133899 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8141279 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 8141279 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26092311 — Safety Biomarker (SAF): DRD2
Study 22752050 — Surrogate Endpoint (SUR): Bone mineral density
Study 20964572 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 20964572 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 16418760 — Surrogate Endpoint (SUR): Blood pressure
Study 14593356 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 14593356 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11001866 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22609079 — Predictive Biomarker (PRD): ARAF mRNA
Genes: ARAF; ARAF1; PKS; PKS2
Study 15938034 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12131781 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12131781 — Safety Biomarker (SAF): CCKAR
Study 2352788 — Surrogate Endpoint (SUR): Forced vital capacity
Study 484262 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 31309627 — Safety Biomarker (SAF): Reactive oxygen species
Study 28412590 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9543282 — Safety Biomarker (SAF): Reactive oxygen species
Study 9543282 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8297217 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 10867212 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9100583 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9100583 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9100583 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27358418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12757987 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8660148 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 7140008 — Surrogate Endpoint (SUR): Blood pressure
Study 24030535 — Safety Biomarker (SAF): Hyaluronic acid
Study 10773104 — Surrogate Endpoint (SUR): Bone mineral density
Study 22883401 — Surrogate Endpoint (SUR): Blood pressure
Study 18076261 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 11996470 — Safety Biomarker (SAF): 51Cr-EDTA
Study 7655177 — Surrogate Endpoint (SUR): Bone mineral density
Study 25742735 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 25742735 — Surrogate Endpoint (SUR): Serum testosterone
Study 15579755 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29388085 — Safety Biomarker (SAF): Hyaluronic acid
Study 22342859 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 2245435 — Surrogate Endpoint (SUR): Blood pressure
Study 16078955 — Surrogate Endpoint (SUR): Blood pressure
Study 10559515 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8528732 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8528732 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 11807724 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 26900640 — Surrogate Endpoint (SUR): Bone mineral density
Study 25100134 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study 25100134 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 25100134 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 25100134 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 25100134 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 18254988 — Surrogate Endpoint (SUR): Bone mineral density
Study 18254988 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26588662 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 26588662 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 19229603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11913007 — Surrogate Endpoint (SUR): Blood pressure
Study 9522325 — Surrogate Endpoint (SUR): Blood pressure
Study 9522325 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9522325 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7526050 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24578074 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 1444555 — Surrogate Endpoint (SUR): Blood pressure
Study 19508590 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 19508590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19508590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15715181 — Safety Biomarker (SAF): DRD2
Study 11889308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11889308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23253948 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 21727662 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 30850876 — Surrogate Endpoint (SUR): Blood pressure
Study 26685004 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 28409515 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22335622 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22335622 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 22335622 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 20823393 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7850821 — Surrogate Endpoint (SUR): Blood pressure
Study 7850821 — Surrogate Endpoint (SUR): Serum potassium
Study 7850821 — Surrogate Endpoint (SUR): Serum uric acid
Study 23302012 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 19059939 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 19059939 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 19059939 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12510813 — Surrogate Endpoint (SUR): Bone mineral density
Study 7994822 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7994822 — Surrogate Endpoint (SUR): Blood pressure
Study 31991203 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 31991203 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 31991203 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 31991203 — Predictive Biomarker (PRD): APOC1 mRNA
Genes: APOC1
Study 31991203 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 31991203 — Predictive Biomarker (PRD): APOD mRNA
Genes: APOD
Study 31991203 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31991203 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 22457321 — Surrogate Endpoint (SUR): Serum testosterone
Study 10068868 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 10068868 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 10068868 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10068868 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 7640325 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7640325 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 2627388 — Surrogate Endpoint (SUR): Blood pressure
Study 793680 — Surrogate Endpoint (SUR): Blood pressure
Study 26075752 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26075752 — Surrogate Endpoint (SUR): Bone mineral density
Study 10996350 — Surrogate Endpoint (SUR): Blood pressure
Study 9313629 — Surrogate Endpoint (SUR): Blood pressure
Study 23427388 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 23427388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18720692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29396097 — Surrogate Endpoint (SUR): Blood pressure
Study 27366132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24930580 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 24930580 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 24930580 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 24930580 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 24930580 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 24930580 — Predictive Biomarker (PRD): GRIK3 mRNA
Genes: GRIK3; GLUR7
Study 11228177 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 11228177 — Surrogate Endpoint (SUR): Serum calcium
Study 7931476 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20496733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20496733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18005471 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18005471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28403798 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4