TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24290869 — Surrogate Endpoint (SUR): Blood pressure
Study 14737055 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8032072 — Surrogate Endpoint (SUR): Blood pressure
Study 29482256 — Surrogate Endpoint (SUR): Serum testosterone
Study 24770624 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 18940711 — Surrogate Endpoint (SUR): Blood pressure
Study 30290680 — Surrogate Endpoint (SUR): Blood pressure
Study 22071709 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 11131930 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8937934 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3479329 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 1426317 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 29193576 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24999076 — Surrogate Endpoint (SUR): Blood pressure
Study 22859825 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20392870 — Surrogate Endpoint (SUR): Serum calcium
Study 20392870 — Surrogate Endpoint (SUR): Bone mineral density
Study 18514933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18514933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18514933 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16200819 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 389839 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 389839 — Surrogate Endpoint (SUR): Blood pressure
Study 30142886 — Surrogate Endpoint (SUR): Blood pressure
Study 16330290 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16330290 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18398348 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9192506 — Surrogate Endpoint (SUR): Bone mineral density
Study 31008545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28783464 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 7955179 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7955179 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28952295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25649019 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 25649019 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21566113 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 16549458 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 14514224 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 31898766 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 16003055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16003055 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24886066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20228003 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17872451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26794937 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17080003 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17080003 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 473853 — Surrogate Endpoint (SUR): Blood pressure
Study 27864127 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 21280267 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 16503582 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 7227621 — Surrogate Endpoint (SUR): Blood pressure
Study 25953494 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 19812443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19812443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19812443 — Monitoring Biomarker (MOI): HBV DNA
Study 27583931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23823329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23823329 — Surrogate Endpoint (SUR): Blood pressure
Study 12185405 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9832077 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2562333 — Safety Biomarker (SAF): Succinate-semialdehyde dehydrogenase
Genes: ALDH5A1; SSADH
Study 29858027 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27250219 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 24184299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24184299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20170345 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 8542857 — Surrogate Endpoint (SUR): Serum potassium
Study 6168829 — Surrogate Endpoint (SUR): Blood pressure
Study 1550043 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1550043 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30150280 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11151453 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8127120 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20329608 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20329608 — Surrogate Endpoint (SUR): Blood pressure
Study 17723882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9562310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23516012 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 17540804 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16563245 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 31535099 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23238293 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16937304 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15665929 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30066796 — Surrogate Endpoint (SUR): Bone mineral density
Study 30066796 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27218676 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23584092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16798186 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 3278232 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18343373 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18343373 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31789451 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31789451 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 14564895 — Surrogate Endpoint (SUR): Blood pressure
Study 14610121 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 15505639 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30293352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28237612 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9778713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9778713 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8310975 — Surrogate Endpoint (SUR): Blood pressure
Study 362831 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31767788 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 23001642 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23001642 — Surrogate Endpoint (SUR): Blood pressure
Study 19755938 — Surrogate Endpoint (SUR): Blood pressure
Study 26149802 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 22892722 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 20651284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 20651284 — Safety Biomarker (SAF): miR-15a
Genes: MIR15A
Study 20651284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 11321183 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31296157 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31296157 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31296157 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31296157 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 31296157 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 31296157 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 28558695 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 28558695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28558695 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21277016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19372044 — Predictive Biomarker (PRD): RITA1 mRNA
Genes: RITA1; C12orf52; RITA; PSEC0043
Study 16569552 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 12473420 — Surrogate Endpoint (SUR): Blood pressure
Study 8252691 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6361565 — Surrogate Endpoint (SUR): Serum creatinine
Study 29498342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24982459 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15767334 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10524689 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10524689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29231363 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 7378213 — Surrogate Endpoint (SUR): Blood pressure
Study 22831548 — Surrogate Endpoint (SUR): Blood pressure
Study 19917377 — Surrogate Endpoint (SUR): Serum uric acid
Study 19917377 — Surrogate Endpoint (SUR): Serum creatinine
Study 28790412 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 28790412 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22165032 — Surrogate Endpoint (SUR): Blood pressure
Study 19368937 — Surrogate Endpoint (SUR): Blood pressure
Study 24191968 — Predictive Biomarker (PRD): NUCB1 mRNA
Genes: NUCB1; NUC
Study 16339289 — Surrogate Endpoint (SUR): Bone mineral density
Study 27012407 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26355026 — Surrogate Endpoint (SUR): Blood pressure
Study 21442823 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21442823 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 31049136 — Surrogate Endpoint (SUR): Blood pressure
Study 21498279 — Surrogate Endpoint (SUR): Serum creatinine
Study 3503114 — Surrogate Endpoint (SUR): Blood pressure
Study 22539077 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 25938778 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23055001 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 23055001 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 22050863 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 9106687 — Predictive Biomarker (PRD): CCHCR1 mRNA
Genes: CCHCR1; C6orf18; HCR
Study 18556683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12449166 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7075651 — Surrogate Endpoint (SUR): Blood pressure
Study 27855099 — Surrogate Endpoint (SUR): Blood pressure
Study 22094472 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17524266 — Monitoring Biomarker (MOI): HBV DNA
Study 12241832 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8205603 — Surrogate Endpoint (SUR): Blood pressure
Study 17488800 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17488800 — Surrogate Endpoint (SUR): Serum potassium
Study 19500003 — Surrogate Endpoint (SUR): Blood pressure
Study 19500003 — Surrogate Endpoint (SUR): Serum creatinine
Study 24614837 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 16954337 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 7768298 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7768298 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 31506096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31506096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24526708 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 24526708 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 17531931 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17531931 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1815226 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24400655 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19772761 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9557925 — Surrogate Endpoint (SUR): Blood pressure
Study 31048758 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 10999089 — Surrogate Endpoint (SUR): Blood pressure
Study 7482166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7482166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31152118 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 26053853 — Surrogate Endpoint (SUR): Blood pressure
Study 15184095 — Surrogate Endpoint (SUR): Blood pressure
Study 8356846 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 31424156 — Predictive Biomarker (PRD): SPESP1 mRNA
Genes: SPESP1; UNQ732/PRO1418
Study 31424156 — Predictive Biomarker (PRD): H4C14 mRNA
Genes: H4C1; H4/A; H4FA; HIST1H4A;; H4C2; H4/I; H4FI; HIST1H4B;; H4C3; H4/G; H4FG; HIST1H4C;; H4C4; H4/B; H4FB; HIST1H4D;; H4C5; H4/J; H4FJ; HIST1H4E;; H4C6; H4/C; H4FC; HIST1H4F;; H4C8; H4/H; H4FH; HIST1H4H;; H4C9; H4/M; H4FM; HIST1H4I;; H4C11; H4/E; H4FE; HIST1H4J;; H4C12; H4/D; H4FD; HIST1H4K;; H4C13; H4/K; H4FK; HIST1H4L;; H4C14; H4/N; H4F2; H4FN; HIST2H4; HIST2H4A;; H4C15; H4/O; H4FO; HIST2H4B;; H4C16; H4-16; HIST4H4
Study 31424156 — Predictive Biomarker (PRD): IZUMO1 mRNA
Genes: IZUMO1
Study 85322 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 85322 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 17666461 — Surrogate Endpoint (SUR): Blood pressure
Study 17335317 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 6762370 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 31362119 — Monitoring Biomarker (MOI): HBV DNA
Study 10559522 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7505360 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30085177 — Surrogate Endpoint (SUR): Blood pressure
Study 30085177 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30085177 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30085177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25323030 — Surrogate Endpoint (SUR): Blood pressure
Study 28200045 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17384435 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17384435 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 17384435 — Surrogate Endpoint (SUR): Serum creatinine
Study 7915067 — Surrogate Endpoint (SUR): Blood pressure
Study 2968052 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29778565 — Surrogate Endpoint (SUR): Blood pressure
Study 8625237 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 7408415 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9875644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9875644 — Safety Biomarker (SAF): Interleukin 1
Study 9875644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7739439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25120316 — Surrogate Endpoint (SUR): Blood pressure
Study 25120316 — Surrogate Endpoint (SUR): Serum creatinine
Study 25120316 — Surrogate Endpoint (SUR): Serum uric acid
Study 12219247 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 8749878 — Surrogate Endpoint (SUR): Blood pressure
Study 16936557 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14505546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11533750 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23684832 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17981067 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 10751812 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10751812 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 27530379 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 27530379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24703319 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24703319 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 24703319 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 24703319 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16547381 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 16547381 — Surrogate Endpoint (SUR): Serum creatinine
Study 10875825 — Surrogate Endpoint (SUR): Blood pressure
Study 18617301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18617301 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15845706 — Surrogate Endpoint (SUR): Blood pressure
Study 11921456 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1184167 — Surrogate Endpoint (SUR): Serum uric acid
Study 18955454 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18955454 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16939990 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8824106 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8824106 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18230792 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 8858403 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 1495520 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1495520 — Surrogate Endpoint (SUR): Blood pressure
Study 22044855 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 17005075 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17005075 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12725259 — Surrogate Endpoint (SUR): Serum creatinine
Study 7909642 — Surrogate Endpoint (SUR): Blood pressure
Study 25775024 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 25775024 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19376750 — Surrogate Endpoint (SUR): Blood pressure
Study 24170101 — Predictive Biomarker (PRD): SOSTDC1 mRNA
Genes: SOSTDC1; USAG1; CDA019
Study 24170101 — Predictive Biomarker (PRD): NFKB2 mRNA
Genes: NFKB2; LYT10
Study 24170101 — Predictive Biomarker (PRD): RELB mRNA
Genes: RELB
Study 16941276 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 28213783 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 28213783 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1