TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11709742 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7815279 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16335673 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15300231 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 3313041 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30931750 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 21122466 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 21122466 — Predictive Biomarker (PRD): DUSP2 mRNA
Genes: DUSP2; PAC1
Study 21122466 — Predictive Biomarker (PRD): MZB1 mRNA
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 29973132 — Surrogate Endpoint (SUR): Plasma testosterone level
Study 20185423 — Monitoring Biomarker (MOI): Procalcitonin
Study 16213926 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 8838703 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16173650 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 12930012 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 12930012 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 10830792 — Surrogate Endpoint (SUR): Blood pressure
Study 29228091 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22492249 — Safety Biomarker (SAF): Hyaluronic acid
Study 17040305 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 12968984 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12968984 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 8473654 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8473654 — Surrogate Endpoint (SUR): Blood pressure
Study 24024773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19296254 — Predictive Biomarker (PRD): ASPRV1 mRNA
Genes: ASPRV1; SASP
Study 19296254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12126263 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12126263 — Surrogate Endpoint (SUR): Blood pressure
Study 9651560 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9638202 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17116177 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17116177 — Surrogate Endpoint (SUR): Blood pressure
Study 31856493 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18074471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18074471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9972958 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2283638 — Surrogate Endpoint (SUR): Blood pressure
Study 6118715 — Surrogate Endpoint (SUR): Blood pressure
Study 6118715 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19739937 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19739937 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12682418 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8561064 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8561064 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29260703 — Surrogate Endpoint (SUR): Blood pressure
Study 10908255 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9302398 — Surrogate Endpoint (SUR): Bone mineral density
Study 29797911 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29797911 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23338230 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 21304082 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 16424704 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12670811 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12670811 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 29305709 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29305709 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29305709 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 15771635 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 23917775 — Predictive Biomarker (PRD): TLR1 mRNA
Genes: TLR1; KIAA0012
Study 16807414 — Surrogate Endpoint (SUR): Serum creatinine
Study 12681523 — Surrogate Endpoint (SUR): Blood pressure
Study 11382829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11382829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11382829 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3438580 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 3438580 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30716679 — Surrogate Endpoint (SUR): Blood pressure
Study 30716679 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30716679 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25475658 — Surrogate Endpoint (SUR): Blood pressure
Study 25475658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25475658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8763802 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17085458 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 9361690 — Predictive Biomarker (PRD): PZP mRNA
Genes: PZP; CPAMD6
Study 27710596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23321990 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29940952 — Safety Biomarker (SAF): miR-206
Genes: MIR206
Study 29940952 — Safety Biomarker (SAF): miR-146b
Genes: MIR146B
Study 27184170 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2671112 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 12745200 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12745200 — Surrogate Endpoint (SUR): Blood pressure
Study 2421120 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27855365 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22614972 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20485161 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 20485161 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15695321 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8747987 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24256611 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24256611 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24256611 — Surrogate Endpoint (SUR): Blood pressure
Study 20414536 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 12133397 — Surrogate Endpoint (SUR): Bone mineral density
Study 24026523 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 23241242 — Surrogate Endpoint (SUR): Blood pressure
Study 15308586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20832550 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 18607338 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8927676 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31026780 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 26739392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26739392 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21290836 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7640145 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2502417 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 15124952 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 11818767 — Surrogate Endpoint (SUR): Blood pressure
Study 15648125 — Surrogate Endpoint (SUR): Blood pressure
Study 8989272 — Surrogate Endpoint (SUR): Bone mineral density
Study 27178897 — Surrogate Endpoint (SUR): Blood pressure
Study 22470429 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21103404 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11700410 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 11700410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11700410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11700410 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3316301 — Surrogate Endpoint (SUR): Blood pressure
Study 28939617 — Surrogate Endpoint (SUR): Blood pressure
Study 24391801 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21189401 — Surrogate Endpoint (SUR): Blood pressure
Study 8147043 — Surrogate Endpoint (SUR): Blood pressure
Study 24710760 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22277987 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22277987 — Surrogate Endpoint (SUR): Blood pressure
Study 20350191 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12841887 — Surrogate Endpoint (SUR): Bone mineral density
Study 12841887 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10597781 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28671000 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28671000 — Safety Biomarker (SAF): BDNF
Study 25644619 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 21791543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3289524 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 29848361 — Surrogate Endpoint (SUR): Serum uric acid
Study 17375114 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10643851 — Monitoring Biomarker (MOI): HBV DNA
Study 9191873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9191873 — Safety Biomarker (SAF): Interleukin 1
Study 9191873 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28639554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21118175 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16603801 — Surrogate Endpoint (SUR): Blood pressure
Study 22966009 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 22966009 — Surrogate Endpoint (SUR): Blood pressure
Study 20451686 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20451686 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28796588 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28796588 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19744307 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30929657 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 23503447 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 23503447 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 23503447 — Predictive Biomarker (PRD): NR1I2 mRNA
Genes: NR1I2; PXR
Study 23503447 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23503447 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 11729740 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 3981950 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 21545249 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15563344 — Surrogate Endpoint (SUR): Blood pressure
Study 25348255 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21341397 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8995995 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 8995995 — Surrogate Endpoint (SUR): Serum potassium
Study 8355469 — Surrogate Endpoint (SUR): Blood pressure
Study 8355469 — Surrogate Endpoint (SUR): Serum creatinine
Study 8355469 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28868878 — Monitoring Biomarker (MOI): HBV DNA
Study 18401223 — Surrogate Endpoint (SUR): Blood pressure
Study 30393935 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 20178395 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20178395 — Surrogate Endpoint (SUR): Blood pressure
Study 28192225 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 24373064 — Surrogate Endpoint (SUR): Blood pressure
Study 10783213 — Surrogate Endpoint (SUR): Blood pressure
Study 10783213 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8624314 — Surrogate Endpoint (SUR): Blood pressure
Study 3886402 — Surrogate Endpoint (SUR): Blood pressure
Study 27542517 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27542517 — Safety Biomarker (SAF): BDNF
Study 10080835 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10080835 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 7590403 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7590403 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7590403 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7428446 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7428446 — Surrogate Endpoint (SUR): Blood pressure
Study 26177480 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 26177480 — Safety Biomarker (SAF): CDA
Genes: CDD
Study 19597420 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19597420 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15353916 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30234480 — Surrogate Endpoint (SUR): Bone mineral density
Study 22775125 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 9924274 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 29676968 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 29676968 — Surrogate Endpoint (SUR): Bone mineral density
Study 29676968 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27380030 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 23312049 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20107154 — Predictive Biomarker (PRD): AFF1 mRNA
Genes: AFF1; AF4; FEL; MLLT2; PBM1
Study 17086009 — Surrogate Endpoint (SUR): Blood pressure
Study 14506629 — Predictive Biomarker (PRD): TRO mRNA
Genes: TRO; KIAA1114; MAGED3
Study 1717789 — Surrogate Endpoint (SUR): Blood pressure
Study 25686683 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21536199 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 15614029 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15614029 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 15614029 — Surrogate Endpoint (SUR): Blood pressure
Study 25494343 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 21850019 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 21850019 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21850019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 20303641 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 19139601 — Surrogate Endpoint (SUR): Blood pressure
Study 8979626 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8979626 — Surrogate Endpoint (SUR): Blood pressure
Study 30121686 — Surrogate Endpoint (SUR): Blood pressure
Study 24569127 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 24569127 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 24569127 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 11967633 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31088530 — Surrogate Endpoint (SUR): Blood pressure
Study 27733466 — Surrogate Endpoint (SUR): Blood pressure
Study 19213769 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14977771 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18512165 — Surrogate Endpoint (SUR): Blood pressure
Study 30967099 — Surrogate Endpoint (SUR): Blood pressure
Study 25997508 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 19567246 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16397129 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 9160765 — Surrogate Endpoint (SUR): Blood pressure
Study 2965232 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 27355499 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16337041 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16337041 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 14602767 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31467510 — Surrogate Endpoint (SUR): Blood pressure
Study 16024131 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12538212 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 10215195 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26537937 — Surrogate Endpoint (SUR): Blood pressure
Study 15982658 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 15982658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12753271 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 8712091 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 8338943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8338943 — Surrogate Endpoint (SUR): Serum creatinine
Study 18076250 — Surrogate Endpoint (SUR): Blood pressure
Study 407056 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31365188 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 31365188 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21302487 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12059064 — Surrogate Endpoint (SUR): Blood pressure
Study 18657146 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 29451696 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8607100 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8607100 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26620682 — Surrogate Endpoint (SUR): Blood pressure
Study 15973830 — Predictive Biomarker (PRD): LDHA mRNA
Genes: LDHA; PIG19
Study 15973830 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 27720505 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 27720505 — Surrogate Endpoint (SUR): Blood pressure
Study 16633088 — Surrogate Endpoint (SUR): Blood pressure
Study 20159703 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30684710 — Surrogate Endpoint (SUR): Serum sodium
Study 25662857 — Surrogate Endpoint (SUR): Blood pressure
Study 23308361 — Surrogate Endpoint (SUR): Blood pressure
Study 21127274 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19149269 — Surrogate Endpoint (SUR): Blood pressure
Study 16534180 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30474929 — Surrogate Endpoint (SUR): Bone mineral density
Study 22690943 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22293584 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22293584 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19927132 — Surrogate Endpoint (SUR): Blood pressure
Study 2128475 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26123388 — Surrogate Endpoint (SUR): Blood pressure
Study 23804517 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 1283192 — Surrogate Endpoint (SUR): Blood pressure
Study 30372582 — Safety Biomarker (SAF): MTHFR
Study 29122196 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 27373347 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 10758465 — Surrogate Endpoint (SUR): Blood pressure
Study 23905576 — Surrogate Endpoint (SUR): Serum potassium
Study 10648452 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 22629160 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22629160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22629160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22629160 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22629160 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16706150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30249940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28411114 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 25627664 — Surrogate Endpoint (SUR): Exhaled carbon monoxide