TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28148280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7282732 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24081011 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 10778882 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10778882 — Predictive Biomarker (PRD): Hormone receptor
Study 30833149 — Safety Biomarker (SAF): Hyaluronic acid
Study 28286061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12014900 — Surrogate Endpoint (SUR): Bacterial count
Study 29059635 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 29059635 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 29059635 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29059635 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19321573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28225446 — Predictive Biomarker (PRD): PLEC mRNA
Genes: PLEC; PLEC1
Study 16371745 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9469674 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29123255 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21940484 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19171204 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 15885046 — Safety Biomarker (SAF): DRD3
Study 10370786 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8880049 — Surrogate Endpoint (SUR): Blood pressure
Study 24889794 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 17579949 — Surrogate Endpoint (SUR): Blood pressure
Study 12050277 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12050277 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17337289 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 8189741 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 29093246 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11138916 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9301553 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8359188 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8359188 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28403961 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28403961 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25920921 — Surrogate Endpoint (SUR): Serum calcium
Study 23142957 — Surrogate Endpoint (SUR): Blood pressure
Study 19133701 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15384954 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9876226 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25633468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18326606 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15008243 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11000669 — Surrogate Endpoint (SUR): Blood pressure
Study 23857943 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18678163 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9988142 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9988142 — Surrogate Endpoint (SUR): Serum calcium
Study 2151747 — Surrogate Endpoint (SUR): Blood pressure
Study 30862692 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30862692 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30862692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30862692 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 30862692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 22524182 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 21222186 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 12736013 — Predictive Biomarker (PRD): PNOC mRNA
Genes: PNOC; OFQ
Study 10789612 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10789612 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31996042 — Predictive Biomarker (PRD): TNR mRNA
Genes: TNR
Study 20831536 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20831536 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10628631 — Surrogate Endpoint (SUR): Serum creatinine
Study 20852182 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 2894165 — Surrogate Endpoint (SUR): Blood pressure
Study 30352568 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 15912074 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9294270 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22342470 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 30015793 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10620203 — Surrogate Endpoint (SUR): Blood pressure
Study 8644056 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8644056 — Surrogate Endpoint (SUR): Blood pressure
Study 20196964 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31099214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31099214 — Safety Biomarker (SAF): Interleukin 1
Study 31099214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11934682 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9473015 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 9473015 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12040250 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12040250 — Surrogate Endpoint (SUR): Blood pressure
Study 7398184 — Surrogate Endpoint (SUR): Blood pressure
Study 31164368 — Surrogate Endpoint (SUR): Blood pressure
Study 24064125 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 24064125 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28599636 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21864846 — Predictive Biomarker (PRD): HRC mRNA
Genes: HRC; HCP
Study 9441288 — Surrogate Endpoint (SUR): Serum creatinine
Study 25595921 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 14671179 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11967820 — Surrogate Endpoint (SUR): Blood pressure
Study 12967792 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 12967792 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 31429950 — Surrogate Endpoint (SUR): Serum creatinine
Study 30078167 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 9069156 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 9069156 — Surrogate Endpoint (SUR): Bone mineral density
Study 26133741 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21982660 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18957616 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31496668 — Surrogate Endpoint (SUR): Blood pressure
Study 24687921 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24687921 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24687921 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 2822878 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2822878 — Surrogate Endpoint (SUR): Blood pressure
Study 26182441 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 24284383 — Surrogate Endpoint (SUR): Blood pressure
Study 2372037 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 480949 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 11330878 — Surrogate Endpoint (SUR): Blood pressure
Study 11330878 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11330878 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11330878 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9401083 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7525055 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 25979307 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25979307 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25979307 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25979307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25979307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25979307 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24061336 — Surrogate Endpoint (SUR): Blood pressure
Study 19336644 — Surrogate Endpoint (SUR): Blood pressure
Study 15215808 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11332163 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 7656918 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15465069 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8006922 — Surrogate Endpoint (SUR): Blood pressure
Study 2006655 — Surrogate Endpoint (SUR): Blood pressure
Study 31402145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16154241 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29550804 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25886645 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21257061 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19074516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19074516 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11391327 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8275350 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 26712779 — Surrogate Endpoint (SUR): Blood pressure
Study 19435203 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19435203 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 19435203 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 16712652 — Predictive Biomarker (PRD): CHIT1 mRNA
Genes: CHIT1
Study 9440758 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 9440758 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 8270988 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 23504930 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8770969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8770969 — Surrogate Endpoint (SUR): Blood pressure
Study 8770969 — Surrogate Endpoint (SUR): Serum creatinine
Study 10694094 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 25687568 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6425480 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 29514712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29514712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26271449 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11573655 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28001147 — Predictive Biomarker (PRD): C12orf57 mRNA
Genes: C12orf57; C10
Study 26080804 — Surrogate Endpoint (SUR): Blood pressure
Study 26080804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26080804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26510263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26510263 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 26510263 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 9416950 — Surrogate Endpoint (SUR): Blood pressure
Study 8387087 — Surrogate Endpoint (SUR): Blood pressure
Study 21921362 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19555469 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 19555469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ESR2 mRNA
Genes: ESR2; ESTRB; NR3A2
Study 19555469 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 19555469 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 9210712 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16865041 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 24095984 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 11332334 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11332334 — Surrogate Endpoint (SUR): Blood pressure
Study 3128139 — Surrogate Endpoint (SUR): Blood pressure
Study 19889805 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study 15618262 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 12469154 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 9012219 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 31158931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31158931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31158931 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 31158931 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31158931 — Safety Biomarker (SAF): IL-6 and IL-10
Study 27164985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27164985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18789118 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 27619750 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 21913027 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9162222 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22065156 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 10028201 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31209667 — Predictive Biomarker (PRD): Microsatellite instability
Study 16760874 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 9413374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20467406 — Safety Biomarker (SAF): Hyaluronic acid
Study 26651260 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26651260 — Surrogate Endpoint (SUR): Blood pressure
Study 24216721 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22898703 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 12410357 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25685772 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18181162 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9032777 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14564595 — Surrogate Endpoint (SUR): Blood pressure
Study 18501783 — Surrogate Endpoint (SUR): Serum creatinine
Study 18501783 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18501783 — Surrogate Endpoint (SUR): Serum uric acid
Study 10072667 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 28862982 — Predictive Biomarker (PRD): SLC22A3 mRNA
Genes: SLC22A3; EMTH; OCT3
Study 20021683 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 7604691 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26131753 — Surrogate Endpoint (SUR): Blood pressure
Study 14579918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14579918 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10375203 — Surrogate Endpoint (SUR): Bone mineral density
Study 25560155 — Surrogate Endpoint (SUR): Serum sodium
Study 25560155 — Surrogate Endpoint (SUR): Serum creatinine
Study 25560155 — Surrogate Endpoint (SUR): Serum potassium
Study 21197498 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 18386572 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18386572 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29621811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12167115 — Predictive Biomarker (PRD): USP9X mRNA
Genes: USP9X; DFFRX; FAM; USP9
Study 1905438 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27528065 — Surrogate Endpoint (SUR): Blood pressure
Study 27528065 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2105087 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31376501 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 21439754 — Surrogate Endpoint (SUR): Blood pressure
Study 21439754 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11402115 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 7818046 — Surrogate Endpoint (SUR): Blood pressure
Study 31334544 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 23475103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14685799 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 14685799 — Predictive Biomarker (PRD): ABCG8 mRNA
Genes: ABCG8
Study 14685799 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2850807 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 2850807 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2850807 — Surrogate Endpoint (SUR): Blood pressure
Study 31859172 — Surrogate Endpoint (SUR): Blood pressure
Study 8809428 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8338403 — Surrogate Endpoint (SUR): Blood pressure
Study 26875428 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23541564 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23541564 — Surrogate Endpoint (SUR): Pathological complete response
Study 15915277 — Surrogate Endpoint (SUR): Blood pressure
Study 22434018 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 18534138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 2736876 — Surrogate Endpoint (SUR): Blood pressure
Study 31782814 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 31782814 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21700922 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 18208636 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 18208636 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 12972982 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 12716087 — Surrogate Endpoint (SUR): Serum creatinine
Study 10232739 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6122111 — Surrogate Endpoint (SUR): Blood pressure
Study 30288819 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 24562449 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 22209386 — Surrogate Endpoint (SUR): Blood pressure
Study 7522282 — Surrogate Endpoint (SUR): Blood pressure
Study 7522282 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3439796 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20338811 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20338811 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 7617607 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7617607 — Surrogate Endpoint (SUR): Blood pressure
Study 2520143 — Surrogate Endpoint (SUR): Blood pressure
Study 2520143 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 405412 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24209829 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15149420 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 17684203 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18408393 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18408393 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10590497 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 10590497 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10999838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10999838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10999838 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8448068 — Surrogate Endpoint (SUR): Blood pressure
Study 27009022 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45