TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05833464 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04644406 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01304524 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT04113616 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT03452111 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study NCT02024243 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-210
Genes: MIR210
Study NCT04276012 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01677650 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT06151002 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT06151002 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT04117945 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02639871 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03477617 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01227070 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT06401941 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT00471497 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00471497 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00514085 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study NCT02515435 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02515435 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00162682 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01172431 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01172431 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04815460 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02491411 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01160445 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03504124 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01224457 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01224457 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00381849 — Surrogate Endpoint (SUR): Urinary cystine
Study NCT03755739 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03755739 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03755739 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01723917 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02692014 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02401399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02899312 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01878513 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT04364698 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03275857 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00799708 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00072449 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04018690 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00924664 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT01932190 — Surrogate Endpoint (SUR): Serum potassium
Study NCT04030338 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00650780 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT04021394 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01162980 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04108585 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02059811 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03547830 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04051073 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04712916 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02698930 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT01266603 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03012893 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study NCT00983372 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02133157 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00063609 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00076141 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01556841 — Predictive Biomarker (PRD): TPBG mRNA
Genes: TPBG; 5T4
Study NCT02488772 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01898234 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00667251 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03756389 — Predictive Biomarker (PRD): BMX mRNA
Genes: BMX
Study NCT01000688 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04077892 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study NCT04077892 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT04077892 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03188601 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT01006863 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01006863 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01006863 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT02563418 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03797001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03797001 — Safety Biomarker (SAF): Interleukin 1
Study NCT03378232 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00245115 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00245115 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01033643 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02923063 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04740424 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT02077621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02077621 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT03388099 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT03547414 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study NCT03547414 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT02091063 — Predictive Biomarker (PRD): HDAC6 mRNA
Genes: HDAC6; KIAA0901; JM21
Study NCT02847325 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT05344287 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05344287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02174276 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02867085 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04511325 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04511325 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04511325 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT04511325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04511325 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04511325 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01142908 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04646824 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04646824 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02685293 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01207141 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study NCT02622425 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00009958 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00009958 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02128009 — Predictive Biomarker (PRD): CLCF1 mRNA
Genes: CLCF1; BSF3; CLC; NNT1
Study NCT02889302 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01762228 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT03970928 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03363698 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00051818 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02805413 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02476305 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study NCT03431896 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT00635336 — Predictive Biomarker (PRD): DEPDC1 mRNA
Genes: DEPDC1; DEPDC1A
Study NCT00635336 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00467311 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT03993639 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04550078 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01819415 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01819415 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03692390 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02608424 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03481855 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03983954 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study NCT03454243 — Predictive Biomarker (PRD): TYRO3 mRNA
Genes: TYRO3; BYK; DTK; RSE; SKY; TIF
Study NCT03454243 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT03454243 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study NCT02846233 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03465111 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02728219 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT01557556 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03105271 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02677246 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01257347 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02005939 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04405908 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00348153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03455036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT02642705 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01429961 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT04509050 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04313296 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT04436133 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01362296 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01362296 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT01362296 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT03526614 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02033317 — Surrogate Endpoint (SUR): Serum potassium
Study NCT04117893 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00098943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03195452 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT01878695 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01867190 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01192750 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT01203917 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01203917 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00917735 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT00917735 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT01686932 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04040686 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01066572 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01950962 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study NCT03087058 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02860325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04352348 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04214288 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00505635 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04196348 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00311220 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study NCT02313051 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03805594 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02299687 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03712202 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT03655483 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT04459676 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study NCT03541239 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT03541239 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study NCT02593019 — Pharmacodynamic Biomarker (PDY): Cyclin-dependent kinase 1
Genes: CDK1; CDC2; CDC28A; CDKN1; P34CDC2
Study NCT02593019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02593019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02593019 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study NCT01711996 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04404140 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03802877 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00808262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04583150 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT05678517 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05678517 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05678517 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04389645 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02948426 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT05455944 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01639716 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT01639716 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT00264680 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00196820 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03864185 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01331239 — Surrogate Endpoint (SUR): Urine free cortisol
Study NCT01531257 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study NCT01531257 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01531257 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00208312 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study NCT02498561 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02755844 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02755844 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study NCT02755844 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02861651 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02861651 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01447355 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT02034435 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03098186 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03098186 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02847585 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT02847585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02847585 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02847585 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT02847585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04403477 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04403477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04403477 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02412475 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02389595 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02682550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02682550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02682550 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01737255 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01960608 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05355467 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03575416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02144766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02144766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00826072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04432207 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03753087 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02304978 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT02304978 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02806791 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02806791 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT02246348 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01096095 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study NCT00461448 — Surrogate Endpoint (SUR): Serum potassium
Study NCT00203320 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01097551 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01627236 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04245293 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02715232 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study NCT02238808 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02791269 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00807066 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00819767 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02292550 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02292550 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02868723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02868723 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04688411 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03430011 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT00590694 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04956445 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01251016 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study NCT02496208 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04433221 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT00091286 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00091286 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01757782 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS