TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00160160 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00331370 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01284205 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT01790737 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02829177 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03335891 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT03335891 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03647839 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT03647839 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00777166 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00558012 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02214940 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT04268732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03867474 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01438567 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT04640324 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study NCT04640324 — Predictive Biomarker (PRD): TM6SF2 mRNA
Genes: TM6SF2
Study NCT04640324 — Predictive Biomarker (PRD): MBOAT7 mRNA
Genes: MBOAT7; BB1; LENG4; OACT7
Study NCT02733042 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03011515 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03011515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04594551 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04531423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03895684 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT02780687 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02780687 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02780687 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT02244047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03112070 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01710397 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02392039 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04012632 — Predictive Biomarker (PRD): KISS1R mRNA
Genes: KISS1R; AXOR12; GPR54
Study NCT04012632 — Predictive Biomarker (PRD): KISS1 mRNA
Genes: KISS1; PP5098
Study NCT03729297 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT03878823 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03878823 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02651844 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT00557570 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00557570 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00331526 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01719406 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03246022 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02462330 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00411450 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02997605 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT01792362 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01163591 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01434108 — Surrogate Endpoint (SUR): Plasma ammonia
Study NCT02245100 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01154972 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT03414190 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02948647 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study NCT00471250 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study NCT04353791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04526210 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT03152656 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study NCT03152656 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study NCT03152656 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03152656 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT03152656 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02835261 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01799772 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02324803 — Predictive Biomarker (PRD): DLL4 mRNA
Genes: DLL4; UNQ1895/PRO4341
Study NCT02324803 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02324803 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT04008225 — Predictive Biomarker (PRD): PNN mRNA
Genes: PNN; DRS; MEMA
Study NCT04111419 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00340769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00340769 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02348229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00253539 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01971814 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01971814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03644771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00132080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03573596 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03573596 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT05409274 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03743766 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03743766 — Predictive Biomarker (PRD): LAG3 mRNA
Genes: LAG3; FDC
Study NCT02532335 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT01900730 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00324714 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02125331 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00137436 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT02264808 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT03923881 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00625456 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03643705 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00055120 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01348724 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT01924078 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01924078 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00152113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00414310 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT01809171 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04675112 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT04675112 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study NCT04675112 — Predictive Biomarker (PRD): TPH2 mRNA
Genes: TPH2; NTPH
Study NCT01548677 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04296149 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT01799798 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study NCT01799798 — Predictive Biomarker (PRD): COL1A2 mRNA
Genes: COL1A2
Study NCT01799798 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02906124 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT02686164 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02874313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00027690 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00027690 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00002572 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04151693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02712957 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT02286128 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT04461925 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02746081 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT03291548 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02653014 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02653014 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01199263 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT02403193 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study NCT02403193 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03508622 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01492777 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01492777 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT03163407 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01285193 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03458429 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03458429 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study NCT01563484 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02100540 — Safety Biomarker (SAF): DRD2
Study NCT00532805 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT01282021 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02646683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03211520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03211520 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01465711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01465711 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02983890 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02983890 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02983890 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT02983890 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01929330 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT04345965 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01357278 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02260089 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02392767 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03376555 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03405402 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study NCT03076112 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03306160 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03213626 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00939003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01915199 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01754025 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03476460 — Surrogate Endpoint (SUR): Serum potassium
Study NCT03476460 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02592161 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02978586 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02415192 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02488694 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02488694 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00570661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00570661 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT06772922 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03897101 — Predictive Biomarker (PRD): ATG5 mRNA
Genes: ATG5; APG5L; ASP
Study NCT01405495 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT04508686 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03920475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03920475 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT03920475 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT03920475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03920475 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT03920475 — Safety Biomarker (SAF): Interleukin 12
Study NCT03920475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03920475 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT02237378 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00569361 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04294810 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04294810 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04294810 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01676103 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03905837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04716166 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01834300 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03478319 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00346814 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00346814 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01519817 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT02310399 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT01196052 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02993796 — Predictive Biomarker (PRD): GALC mRNA
Genes: GALC
Study NCT03012789 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study NCT00306904 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02640976 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02640976 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ESR2 mRNA
Genes: ESR2; ESTRB; NR3A2
Study NCT02171754 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03776474 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT04119349 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT03259152 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT03259152 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT00202501 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03513666 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05687097 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04574453 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00924560 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04538664 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00999037 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02501746 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03186144 — Predictive Biomarker (PRD): CHD7 mRNA
Genes: CHD7; KIAA1416
Study NCT01904110 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01861132 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01163747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02250495 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04069221 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00077948 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00145886 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03461198 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00205231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00205231 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01753713 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03596372 — Predictive Biomarker (PRD): CEACAM6 mRNA
Genes: CEACAM6; NCA
Study NCT04285567 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02728258 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT03182244 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT03971006 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study NCT03039751 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01606215 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01424839 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT02104427 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02104427 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02104427 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01425736 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01425736 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04553172 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT01304797 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04789525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03084419 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00979732 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01356849 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02979015 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02979015 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01628302 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01628302 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00206960 — Safety Biomarker (SAF): DRD2
Study NCT01602952 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02016768 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01826422 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00028717 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02381106 — Predictive Biomarker (PRD): ADRB3 mRNA
Genes: ADRB3; ADRB3R; B3AR
Study NCT03926585 — Predictive Biomarker (PRD): DIO2 mRNA
Genes: DIO2; ITDI2; TXDI2
Study NCT01562847 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00231270 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01776840 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03225287 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT03193047 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03193047 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01866449 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00371956 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00004879 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04527354 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01801709 — Predictive Biomarker (PRD): ARSA mRNA
Genes: ARSA
Study NCT02262611 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01386411 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53