TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29663291 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27062051 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 18834466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12706704 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 26825736 — Surrogate Endpoint (SUR): Serum uric acid
Study 24964176 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23234606 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 15307936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15307936 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15307936 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11479247 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30661836 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22350679 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20212073 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31880826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31880826 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 31880826 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31880826 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 31880826 — Predictive Biomarker (PRD): PIK3R1 mRNA
Genes: PIK3R1; GRB1
Study 31880826 — Predictive Biomarker (PRD): PIK3R2 mRNA
Genes: PIK3R2
Study 31880826 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 23713812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23713812 — Safety Biomarker (SAF): Interleukin 1
Study 21627399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21627399 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 14582592 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 6376208 — Surrogate Endpoint (SUR): Blood pressure
Study 6376208 — Surrogate Endpoint (SUR): Serum potassium
Study 10981089 — Surrogate Endpoint (SUR): Blood pressure
Study 7789479 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2206033 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2206033 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 388220 — Surrogate Endpoint (SUR): Blood pressure
Study 388220 — Surrogate Endpoint (SUR): Serum creatinine
Study 15577823 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9249783 — Surrogate Endpoint (SUR): Blood pressure
Study 9249783 — Surrogate Endpoint (SUR): Serum creatinine
Study 22300367 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 22300367 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 17993763 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8038616 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31138332 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28972673 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25208361 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 17449497 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 14718403 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 14718403 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28976605 — Predictive Biomarker (PRD): ELOVL5 mRNA
Genes: ELOVL5; ELOVL2; PRO0530
Study 16422974 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 2001016 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 27188901 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 27188901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27188901 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27188901 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15240119 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16102936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9173811 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7968752 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 3295037 — Surrogate Endpoint (SUR): Blood pressure
Study 26632907 — Surrogate Endpoint (SUR): Serum creatinine
Study 23286943 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17199455 — Surrogate Endpoint (SUR): Bone mineral density
Study 10372701 — Surrogate Endpoint (SUR): Bone mineral density
Study 30845047 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 16455835 — Surrogate Endpoint (SUR): Blood pressure
Study 11544424 — Surrogate Endpoint (SUR): Serum creatinine
Study 8433235 — Surrogate Endpoint (SUR): Serum sodium
Study 8560681 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 8560681 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31442441 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 8807592 — Surrogate Endpoint (SUR): Serum potassium
Study 6094868 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 10378663 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25994910 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 25994910 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 25994910 — Predictive Biomarker (PRD): AFF1 mRNA
Genes: AFF1; AF4; FEL; MLLT2; PBM1
Study 21957625 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 19048458 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 11715490 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19666395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9820445 — Surrogate Endpoint (SUR): Serum potassium
Study 27497779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25600772 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 25600772 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 16412731 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 3549162 — Predictive Biomarker (PRD): SPHK1 mRNA
Genes: SPHK1; SK1; SPHK; SPK
Study 24295873 — Monitoring Biomarker (MOI): HBV DNA
Study 20573750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12618567 — Surrogate Endpoint (SUR): Blood pressure
Study 30073778 — Surrogate Endpoint (SUR): Bone mineral density
Study 11276031 — Surrogate Endpoint (SUR): Blood pressure
Study 31299951 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 19023276 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 19023276 — Surrogate Endpoint (SUR): Blood pressure
Study 9593759 — Surrogate Endpoint (SUR): Blood pressure
Study 30898253 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25996285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21793690 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 11500334 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1099184 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 22921476 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 18523220 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 18523220 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 18523220 — Predictive Biomarker (PRD): Microsatellite instability
Study 16564279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16564279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16564279 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30694099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20592433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10479130 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28847468 — Surrogate Endpoint (SUR): Blood pressure
Study 17435356 — Surrogate Endpoint (SUR): Blood pressure
Study 10574417 — Surrogate Endpoint (SUR): Serum creatinine
Study 8918516 — Surrogate Endpoint (SUR): Serum creatinine
Study 29968187 — Surrogate Endpoint (SUR): Bone mineral density
Study 26889974 — Safety Biomarker (SAF): Derived neutrophil to lymphocyte
Study 26889974 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 25153791 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20960535 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20960535 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20960535 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17363756 — Surrogate Endpoint (SUR): Blood pressure
Study 12577231 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12577231 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9727545 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22725648 — Surrogate Endpoint (SUR): Blood pressure
Study 16132930 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 9987151 — Safety Biomarker (SAF): Human leucocyte antigen
Study 9987151 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 27769585 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 2149017 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2149017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2149017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21781066 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21781066 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 19346367 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12915334 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12915334 — Safety Biomarker (SAF): Interleukin 1
Study 12915334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12915334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9162737 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3288468 — Surrogate Endpoint (SUR): Blood pressure
Study 12796167 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 6805590 — Surrogate Endpoint (SUR): Blood pressure
Study 9505799 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 28146403 — Safety Biomarker (SAF): Hyaluronic acid
Study 28146403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25724409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25724409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10866898 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9069159 — Surrogate Endpoint (SUR): Bone mineral density
Study 25029424 — Surrogate Endpoint (SUR): Serum calcium
Study 25029424 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31695350 — Surrogate Endpoint (SUR): Blood pressure
Study 11096234 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11096234 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 14959469 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18796000 — Surrogate Endpoint (SUR): Bone mineral density
Study 14992899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14992899 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 14992899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14992899 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 14992899 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2954221 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 27843803 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27843803 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 27843803 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 27843803 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23046438 — Surrogate Endpoint (SUR): Blood pressure
Study 11198487 — Surrogate Endpoint (SUR): Blood pressure
Study 8649658 — Surrogate Endpoint (SUR): Bone mineral density
Study 8649658 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 8649658 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 30853602 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 30311885 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23881774 — Surrogate Endpoint (SUR): Blood pressure
Study 21441616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21441616 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 334211 — Surrogate Endpoint (SUR): Blood pressure
Study 31216226 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 31216226 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 27895192 — Surrogate Endpoint (SUR): Blood pressure
Study 17416480 — Surrogate Endpoint (SUR): Serum creatinine
Study 11167428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11167428 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11167428 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 11167428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11167428 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 11167428 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11167428 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8158887 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8158887 — Surrogate Endpoint (SUR): Blood pressure
Study 21860557 — Surrogate Endpoint (SUR): Blood pressure
Study 14627786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26601092 — Surrogate Endpoint (SUR): Blood pressure
Study 15349784 — Surrogate Endpoint (SUR): Plasma ammonia
Study 9310273 — Surrogate Endpoint (SUR): Blood pressure
Study 3554278 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30830164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30830164 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 30830164 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26780387 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25280420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21146655 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 29886779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23233719 — Predictive Biomarker (PRD): Hormone receptor
Study 25314773 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17209215 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 14997933 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 14997933 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 14997933 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14997933 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 14997933 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 14997933 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 14997933 — Predictive Biomarker (PRD): PSMB8 mRNA
Genes: PSMB8; LMP7; PSMB5i; RING10; Y2
Study 14997933 — Predictive Biomarker (PRD): PSMB9 mRNA
Genes: PSMB9; LMP2; PSMB6i; RING12
Study 14997933 — Predictive Biomarker (PRD): PSMB10 mRNA
Genes: PSMB10; LMP10; MECL1
Study 14997933 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28829514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3126515 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 29367614 — Surrogate Endpoint (SUR): Blood pressure
Study 16319330 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11986591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11986591 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2677101 — Surrogate Endpoint (SUR): Blood pressure
Study 26226350 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 24183037 — Predictive Biomarker (PRD): PLAA mRNA
Genes: PLAA; PLAP
Study 25852025 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21131468 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9673264 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9673264 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 812887 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 14763920 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9164314 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17951619 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16977262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10888969 — Surrogate Endpoint (SUR): Blood pressure
Study 16579002 — Surrogate Endpoint (SUR): Blood pressure
Study 16579002 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6997522 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25783974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20671295 — Surrogate Endpoint (SUR): Blood pressure
Study 11490143 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 7589026 — Surrogate Endpoint (SUR): Blood pressure
Study 31707832 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31707832 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7946181 — Surrogate Endpoint (SUR): Blood pressure
Study 7946181 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19954052 — Surrogate Endpoint (SUR): Serum creatinine
Study 17961403 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17961403 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15336593 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 15336593 — Surrogate Endpoint (SUR): Bone mineral density
Study 2455148 — Surrogate Endpoint (SUR): Blood pressure
Study 23695207 — Surrogate Endpoint (SUR): Blood pressure
Study 23695207 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10889113 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 4002782 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27085261 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20361031 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15834592 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31402735 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 19602503 — Surrogate Endpoint (SUR): Blood pressure
Study 19602503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31428908 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31428908 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23123382 — Surrogate Endpoint (SUR): Blood pressure
Study 14985220 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 14985220 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27401788 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27401788 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF