TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31076466 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 27618363 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 24089671 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11374602 — Surrogate Endpoint (SUR): Blood pressure
Study 12427146 — Surrogate Endpoint (SUR): Serum creatinine
Study 27754427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23488280 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23488280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23488280 — Surrogate Endpoint (SUR): Blood pressure
Study 15516696 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15516696 — Surrogate Endpoint (SUR): Serum creatinine
Study 15516696 — Surrogate Endpoint (SUR): Blood pressure
Study 21926427 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21926427 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20395869 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18315579 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10327193 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31454045 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 19610264 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9520629 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 9520629 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18974448 — Surrogate Endpoint (SUR): Bone mineral density
Study 16550299 — Surrogate Endpoint (SUR): Bone mineral density
Study 11107867 — Surrogate Endpoint (SUR): Bone mineral density
Study 26140541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26140541 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26140541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11525272 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 11525272 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18163011 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30382308 — Surrogate Endpoint (SUR): Blood pressure
Study 27289174 — Predictive Biomarker (PRD): ARSA mRNA
Genes: ARSA
Study 24715381 — Predictive Biomarker (PRD): GPER1 mRNA
Genes: GPER1; CEPR; CMKRL2; DRY12; GPER; GPR30
Study 24715381 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24715381 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16780390 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30853012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24432670 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 24432670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19638231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12457031 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study 12457031 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 22101218 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19037197 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17151339 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 15096906 — Surrogate Endpoint (SUR): Blood pressure
Study 25854575 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25854575 — Safety Biomarker (SAF): Th2 cell
Study 25854575 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19583607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19583607 — Safety Biomarker (SAF): IL-6 and IL-10
Study 27316539 — Surrogate Endpoint (SUR): Blood pressure
Study 24600660 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10096580 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21251162 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21849264 — Surrogate Endpoint (SUR): Bone mineral density
Study 10928231 — Surrogate Endpoint (SUR): Serum triglycerides
Study 3908332 — Surrogate Endpoint (SUR): Blood pressure
Study 23587660 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 20456545 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 16581897 — Surrogate Endpoint (SUR): Blood pressure
Study 11687774 — Surrogate Endpoint (SUR): Blood pressure
Study 21280316 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15855323 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 1506600 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1506600 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29443767 — Surrogate Endpoint (SUR): Blood pressure
Study 9592327 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 9592327 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1649720 — Surrogate Endpoint (SUR): Blood pressure
Study 3935120 — Surrogate Endpoint (SUR): Serum potassium
Study 29590326 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20437207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20437207 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15818745 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 29695772 — Surrogate Endpoint (SUR): Blood pressure
Study 25081390 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24091318 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 1427652 — Monitoring Biomarker (MOI): HBV DNA
Study 15803929 — Surrogate Endpoint (SUR): Serum creatinine
Study 31845065 — Surrogate Endpoint (SUR): Serum uric acid
Study 26158178 — Safety Biomarker (SAF): IL-6 and IL-10
Study 23071718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23071718 — Surrogate Endpoint (SUR): Blood pressure
Study 9260729 — Surrogate Endpoint (SUR): Blood pressure
Study 16159849 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 3113957 — Surrogate Endpoint (SUR): Blood pressure
Study 28933582 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 23525529 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9316554 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9316554 — Surrogate Endpoint (SUR): Serum creatinine
Study 24401022 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 22874517 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 20555135 — Surrogate Endpoint (SUR): Blood pressure
Study 10360660 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27064975 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22301477 — Surrogate Endpoint (SUR): Bone mineral density
Study 20584070 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20584070 — Surrogate Endpoint (SUR): Blood pressure
Study 20584070 — Surrogate Endpoint (SUR): Serum creatinine
Study 17675590 — Predictive Biomarker (PRD): HINT1 mRNA
Genes: HINT1; HINT; PKCI1; PRKCNH1
Study 17675590 — Predictive Biomarker (PRD): FOXM1 mRNA
Genes: FOXM1; FKHL16; HFH11; MPP2; WIN
Study 12401533 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27423381 — Predictive Biomarker (PRD): miR-31
Genes: MIR31
Study 24977688 — Surrogate Endpoint (SUR): Blood pressure
Study 22315014 — Surrogate Endpoint (SUR): Bone mineral density
Study 6790805 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16680561 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30934894 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21809909 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10227413 — Surrogate Endpoint (SUR): Blood pressure
Study 8707278 — Monitoring Biomarker (MOI): HBV DNA
Study 28570603 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25078946 — Surrogate Endpoint (SUR): Blood pressure
Study 22492501 — Surrogate Endpoint (SUR): Serum calcium
Study 22492501 — Surrogate Endpoint (SUR): Bone mineral density
Study 17202798 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3535621 — Surrogate Endpoint (SUR): Blood pressure
Study 27018532 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 20438514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20438514 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18640108 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 12665540 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19895590 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12460865 — Surrogate Endpoint (SUR): Blood pressure
Study 31775696 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 29246256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29246256 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24825180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17538639 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17538639 — Surrogate Endpoint (SUR): Serum testosterone
Study 22187510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9886446 — Surrogate Endpoint (SUR): Blood pressure
Study 7792793 — Surrogate Endpoint (SUR): Blood pressure
Study 19463125 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29250545 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29250545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29250545 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 29250545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29250545 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8405631 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8405631 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2945332 — Surrogate Endpoint (SUR): Blood pressure
Study 23297844 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16977507 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 14749454 — Surrogate Endpoint (SUR): Bone mineral density
Study 11705818 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24947792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24947792 — Surrogate Endpoint (SUR): Blood pressure
Study 8310508 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28919708 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 28919708 — Safety Biomarker (SAF): Interleukin 1
Study 28919708 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9549739 — Surrogate Endpoint (SUR): Blood pressure
Study 3190999 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3190999 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22884136 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10215671 — Surrogate Endpoint (SUR): Blood pressure
Study 10215671 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30418227 — Surrogate Endpoint (SUR): Blood pressure
Study 30165610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26304967 — Surrogate Endpoint (SUR): Blood pressure
Study 26304967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23210563 — Surrogate Endpoint (SUR): Blood pressure
Study 18453793 — Surrogate Endpoint (SUR): Blood pressure
Study 23253744 — Surrogate Endpoint (SUR): Blood pressure
Study 16441950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8764120 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6282434 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 30536595 — Surrogate Endpoint (SUR): Blood pressure
Study 26574019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26574019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15087598 — Surrogate Endpoint (SUR): Blood pressure
Study 9003479 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8622389 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8622389 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31877631 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 25027821 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20667082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20667082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17993041 — Surrogate Endpoint (SUR): Blood pressure
Study 15541408 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 8995749 — Surrogate Endpoint (SUR): Serum calcium
Study 27143690 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 27004344 — Predictive Biomarker (PRD): OAS1 mRNA
Genes: OAS1; OIAS
Study 24078509 — Surrogate Endpoint (SUR): Serum creatinine
Study 21360491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10970994 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10970994 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26520396 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 19606690 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23604689 — Surrogate Endpoint (SUR): Serum testosterone
Study 21476064 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 8017327 — Surrogate Endpoint (SUR): Blood pressure
Study 8017327 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30875390 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30875390 — Surrogate Endpoint (SUR): Serum calcium
Study 20458210 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20458210 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14559383 — Surrogate Endpoint (SUR): Blood pressure
Study 10710555 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10710555 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 9181268 — Surrogate Endpoint (SUR): Blood pressure
Study 19590158 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 16327030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9784543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9784543 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9784543 — Predictive Biomarker (PRD): C4BPA mRNA
Genes: C4BPA; C4BP
Study 9784543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7664863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7664863 — Safety Biomarker (SAF): Interleukin 1
Study 20386125 — Surrogate Endpoint (SUR): Blood pressure
Study 18436117 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 18436117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16950753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16950753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12759881 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 8477190 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3797397 — Surrogate Endpoint (SUR): Blood pressure
Study 20400408 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18722869 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14626182 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14626182 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14626182 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9190630 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25894123 — Surrogate Endpoint (SUR): Blood pressure
Study 14683522 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8290458 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 3014110 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22233558 — Surrogate Endpoint (SUR): Probing pocket depth
Study 20444751 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20444751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15837944 — Surrogate Endpoint (SUR): Blood pressure
Study 10516539 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 10516539 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 30889042 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 30889042 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 30889042 — Predictive Biomarker (PRD): SLC28A1 mRNA
Genes: SLC28A1; CNT1
Study 30889042 — Predictive Biomarker (PRD): Equilibrative nucleoside transporter 2
Genes: SLC29A2; DER12; ENT2; HNP36
Study 30889042 — Predictive Biomarker (PRD): TGFB2 mRNA
Genes: TGFB2
Study 24915778 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 7538556 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17890965 — Surrogate Endpoint (SUR): Blood pressure
Study 25524863 — Surrogate Endpoint (SUR): Blood pressure
Study 22172255 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19586556 — Monitoring Biomarker (MOI): HBV DNA
Study 9568678 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 8043996 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 8043996 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12660585 — Surrogate Endpoint (SUR): Blood pressure
Study 3513516 — Surrogate Endpoint (SUR): Blood pressure
Study 11941903 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11941903 — Surrogate Endpoint (SUR): Blood pressure
Study 10024093 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19542895 — Surrogate Endpoint (SUR): Blood pressure
Study 22751169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18703937 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 1325880 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26768146 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20405117 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7783097 — Surrogate Endpoint (SUR): Blood pressure
Study 26792619 — Surrogate Endpoint (SUR): Blood pressure
Study 10638393 — Safety Biomarker (SAF): Reactive oxygen species
Study 27443226 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 27443226 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 24026563 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 9708514 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 23510018 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23510018 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15272397 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 31620896 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 30839090 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 27698102 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21346110 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 16391591 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12175635 — Predictive Biomarker (PRD): C4A mRNA
Genes: C4A; CO4; CPAMD2
Study 7005293 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29926675 — Surrogate Endpoint (SUR): Blood pressure
Study 29926675 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29926675 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10520573 — Surrogate Endpoint (SUR): Serum testosterone
Study 15145964 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15145964 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 1646621 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1646621 — Surrogate Endpoint (SUR): Blood pressure
Study 24718367 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 24718367 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19