TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9273875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31062044 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 11676993 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 9648079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9648079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9648079 — Surrogate Endpoint (SUR): Serum creatinine
Study 796739 — Surrogate Endpoint (SUR): Serum creatinine
Study 796739 — Surrogate Endpoint (SUR): Blood pressure
Study 21672123 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 12767952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 30409830 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29750475 — Surrogate Endpoint (SUR): Blood pressure
Study 11181283 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 8169337 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16580659 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 12202120 — Safety Biomarker (SAF): Hyaluronic acid
Study 7813259 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30887607 — Surrogate Endpoint (SUR): Bone mineral density
Study 9185028 — Surrogate Endpoint (SUR): Blood pressure
Study 25650044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18852183 — Surrogate Endpoint (SUR): Blood pressure
Study 18852183 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9004446 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29235162 — Predictive Biomarker (PRD): Liver iron
Study 24488335 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24488335 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 24488335 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10561135 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10561135 — Surrogate Endpoint (SUR): Blood pressure
Study 10561135 — Surrogate Endpoint (SUR): Serum creatinine
Study 10561135 — Safety Biomarker (SAF): Urinary total protein
Study 7968327 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 3371390 — Surrogate Endpoint (SUR): Blood pressure
Study 21917874 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 10862446 — Surrogate Endpoint (SUR): Blood pressure
Study 3709379 — Surrogate Endpoint (SUR): Blood pressure
Study 3940620 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1661216 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31167663 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 21114535 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 17106317 — Surrogate Endpoint (SUR): Blood pressure
Study 7566576 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22847248 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 10430726 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30336824 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30336824 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26749079 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23139071 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22197412 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11586670 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28433454 — Surrogate Endpoint (SUR): Blood pressure
Study 22845008 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22845008 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 17136940 — Surrogate Endpoint (SUR): Blood pressure
Study 24934787 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24934787 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20214460 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 23344545 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 21215809 — Predictive Biomarker (PRD): GSTA1 mRNA
Genes: GSTA1
Study 21215809 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 28902035 — Safety Biomarker (SAF): Hyaluronic acid
Study 21389332 — Surrogate Endpoint (SUR): Blood pressure
Study 16546673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 28374849 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28374849 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16828301 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8269716 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 11111143 — Surrogate Endpoint (SUR): Blood pressure
Study 8656243 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1893612 — Surrogate Endpoint (SUR): Blood pressure
Study 24995890 — Surrogate Endpoint (SUR): Blood pressure
Study 27154904 — Surrogate Endpoint (SUR): Blood pressure
Study 19061712 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16548348 — Safety Biomarker (SAF): Interleukin 1
Study 16548348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1521210 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 24958315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22322544 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 26926656 — Surrogate Endpoint (SUR): Blood pressure
Study 16231362 — Surrogate Endpoint (SUR): Bone mineral density
Study 21283736 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9600501 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23233371 — Surrogate Endpoint (SUR): Blood pressure
Study 27813395 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 27813395 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 12149659 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 30945504 — Surrogate Endpoint (SUR): Blood pressure
Study 30945504 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28917230 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28917230 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14661011 — Surrogate Endpoint (SUR): Blood pressure
Study 24622414 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 9459116 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 24622832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20435245 — Surrogate Endpoint (SUR): Blood pressure
Study 14675880 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31292969 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 31292969 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 27662341 — Predictive Biomarker (PRD): TNC mRNA
Genes: TNC; HXB
Study 27662341 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 27662341 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27662341 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 27662341 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 24467256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24467256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24467256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15076791 — Surrogate Endpoint (SUR): Bone mineral density
Study 8021907 — Surrogate Endpoint (SUR): Blood pressure
Study 8021907 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2640054 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 811471 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31927662 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8367870 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31393628 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 16915107 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7782660 — Surrogate Endpoint (SUR): Blood pressure
Study 1777832 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31240995 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22032053 — Surrogate Endpoint (SUR): Blood pressure
Study 18617640 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1623866 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30129426 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30129426 — Predictive Biomarker (PRD): AKT1S1 mRNA
Genes: AKT1S1; PRAS40
Study 30129426 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 25609654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25609654 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18991077 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16842669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31160171 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31160171 — Predictive Biomarker (PRD): Hormone receptor
Study 16248238 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 31036422 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 24717791 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 4076202 — Surrogate Endpoint (SUR): Blood pressure
Study 29611029 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 29611029 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 11902267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11902267 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26817929 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 22362012 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15578203 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 15578203 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1969980 — Surrogate Endpoint (SUR): Blood pressure
Study 358738 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 30737046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27097790 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 9553912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7934767 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7934767 — Surrogate Endpoint (SUR): Blood pressure
Study 12437706 — Surrogate Endpoint (SUR): Blood pressure
Study 26584195 — Safety Biomarker (SAF): Interleukin 1
Study 24657803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17143187 — Surrogate Endpoint (SUR): Blood pressure
Study 7977146 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24513589 — Surrogate Endpoint (SUR): Blood pressure
Study 20795385 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20795385 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 10028858 — Monitoring Biomarker (MOI): HBV DNA
Study 19826270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19826270 — Safety Biomarker (SAF): Reactive oxygen species
Study 19826270 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25509057 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25509057 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22166848 — Surrogate Endpoint (SUR): Blood pressure
Study 19384953 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 19384953 — Predictive Biomarker (PRD): TYRP1 mRNA
Genes: TYRP1; CAS2; TYRP; TYRRP
Study 19384953 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 19384953 — Predictive Biomarker (PRD): SLC24A5 mRNA
Genes: SLC24A5; JSX; NCKX5
Study 19384953 — Predictive Biomarker (PRD): SLC45A2 mRNA
Genes: SLC45A2; AIM1; MATP
Study 19384953 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 19384953 — Predictive Biomarker (PRD): ATRN mRNA
Genes: ATRN; KIAA0548; MGCA
Study 19384953 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study 9067498 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 28065453 — Surrogate Endpoint (SUR): Serum creatinine
Study 26239594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27107066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25060946 — Surrogate Endpoint (SUR): Blood pressure
Study 7729938 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 7729938 — Predictive Biomarker (PRD): Hormone receptor
Study 7027894 — Surrogate Endpoint (SUR): Blood pressure
Study 9151051 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30527153 — Surrogate Endpoint (SUR): Blood pressure
Study 26252788 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 26252788 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 25047139 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15657372 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15657372 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15657372 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15657372 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10789879 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3831144 — Surrogate Endpoint (SUR): Blood pressure
Study 30661944 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30661944 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30661944 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30661944 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25151225 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20131030 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 23264241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23264241 — Surrogate Endpoint (SUR): Blood pressure
Study 18159027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9797910 — Surrogate Endpoint (SUR): Bone mineral density
Study 9797910 — Surrogate Endpoint (SUR): Serum calcium
Study 8586825 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8586825 — Surrogate Endpoint (SUR): Blood pressure
Study 29262813 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29262813 — Surrogate Endpoint (SUR): Blood pressure
Study 23636255 — Safety Biomarker (SAF): DRD2
Study 19615907 — Surrogate Endpoint (SUR): Serum potassium
Study 28571996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22064591 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18636266 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 18636266 — Predictive Biomarker (PRD): CA4 mRNA
Genes: CA4
Study 16959828 — Surrogate Endpoint (SUR): Serum creatinine
Study 31130722 — Predictive Biomarker (PRD): Hormone receptor
Study 31130722 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26618455 — Safety Biomarker (SAF): Hyaluronic acid
Study 30655182 — Surrogate Endpoint (SUR): Blood pressure
Study 14760157 — Surrogate Endpoint (SUR): Bone mineral density
Study 11313304 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 11313304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31873772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21981454 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 21981454 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 21981454 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study 21981454 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 21981454 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 8276050 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8276050 — Surrogate Endpoint (SUR): Blood pressure
Study 21334854 — Safety Biomarker (SAF): MTHFR
Study 17130431 — Predictive Biomarker (PRD): CCR1 mRNA
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 18031294 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12115321 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10336919 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10336919 — Surrogate Endpoint (SUR): Blood pressure
Study 30789780 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 22613136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11642510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7882780 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23314694 — Surrogate Endpoint (SUR): Blood pressure
Study 20498403 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 14620390 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1465034 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1465034 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29907581 — Surrogate Endpoint (SUR): Bone mineral density
Study 26465829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11982742 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3024869 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30858203 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24648103 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 18555464 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 7586952 — Surrogate Endpoint (SUR): Blood pressure
Study 31646414 — Surrogate Endpoint (SUR): Blood pressure
Study 15569128 — Surrogate Endpoint (SUR): Blood pressure
Study 15569128 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8154425 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30153859 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 25220898 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23194489 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 23194489 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20162301 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20162301 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 7033946 — Surrogate Endpoint (SUR): Blood pressure
Study 19394503 — Surrogate Endpoint (SUR): Serum creatinine
Study 10775552 — Surrogate Endpoint (SUR): Blood pressure
Study 3919803 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18569935 — Surrogate Endpoint (SUR): Serum potassium
Study 8475869 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8475869 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30318515 — Predictive Biomarker (PRD): TGFBR1 mRNA
Genes: TGFBR1; ALK5; SKR4
Study 30318515 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 30318515 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21684626 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15883316 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 15883316 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 10734323 — Surrogate Endpoint (SUR): Blood pressure
Study 28640770 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28640770 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 11163733 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8104270 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3943286 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24358145 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 31161196 — Surrogate Endpoint (SUR): Blood pressure
Study 23526069 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23526069 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1