TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18334144 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 16799817 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30371283 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30371283 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 23612435 — Predictive Biomarker (PRD): OPRD1 mRNA
Genes: OPRD1; OPRD
Study 16488335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12422907 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7724390 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26791678 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26791678 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26791678 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18375896 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18375896 — Predictive Biomarker (PRD): Hormone receptor
Study 16683008 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30352580 — Surrogate Endpoint (SUR): Blood pressure
Study 27220960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 27220960 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27220960 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 27220960 — Predictive Biomarker (PRD): VEGFC mRNA
Genes: VEGFC
Study 27220960 — Predictive Biomarker (PRD): EPGN mRNA
Genes: EPGN; UNQ3072/PRO9904
Study 22524549 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19937133 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19937133 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15711353 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 1484945 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1484945 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14551237 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14551237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27151222 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19678756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19678756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19678756 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19390223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19390223 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29921161 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 24934276 — Predictive Biomarker (PRD): ORMDL3 mRNA
Genes: ORMDL3
Study 24934276 — Predictive Biomarker (PRD): GSDMB mRNA
Genes: GSDMB; GSDML; PP4052; PRO2521
Study 24934276 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 24934276 — Predictive Biomarker (PRD): F13A1 mRNA
Genes: F13A1; F13A
Study 7560599 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 25994603 — Surrogate Endpoint (SUR): Blood pressure
Study 21640424 — Surrogate Endpoint (SUR): Blood pressure
Study 15040544 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9713731 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9713731 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 9713731 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 18305079 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11319567 — Surrogate Endpoint (SUR): Blood pressure
Study 11319567 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21652220 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 21652220 — Surrogate Endpoint (SUR): Serum calcium
Study 17554581 — Surrogate Endpoint (SUR): Bone mineral density
Study 12584837 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24289591 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 3555898 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 17199580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2547560 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 23794107 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 21183746 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 31876643 — Surrogate Endpoint (SUR): Blood pressure
Study 10506601 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study 10506601 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10506601 — Predictive Biomarker (PRD): Hormone receptor
Study 1855763 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1855763 — Surrogate Endpoint (SUR): Blood pressure
Study 27069360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27069360 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25304727 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22789797 — Surrogate Endpoint (SUR): Blood pressure
Study 22789797 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15499224 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 15499224 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15499224 — Surrogate Endpoint (SUR): Plasma testosterone level
Study 21693699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21693699 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21693699 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18300746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18300746 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16608780 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14600575 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14600575 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8782296 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31903773 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31903773 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21031578 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study 21031578 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 12368364 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 322921 — Surrogate Endpoint (SUR): Blood pressure
Study 24704626 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 24704626 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 24704626 — Monitoring Biomarker (MOI): Apolipoprotein C-II
Genes: APOC2; APC2
Study 24704626 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 24704626 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12814810 — Surrogate Endpoint (SUR): Blood pressure
Study 8973752 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 30229683 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 30229683 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 20038730 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11804991 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 11804991 — Predictive Biomarker (PRD): NE
Study 11804991 — Surrogate Endpoint (SUR): Blood pressure
Study 8566936 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8566936 — Surrogate Endpoint (SUR): Blood pressure
Study 2884856 — Surrogate Endpoint (SUR): Blood pressure
Study 12218723 — Surrogate Endpoint (SUR): Bone mineral density
Study 9468457 — Predictive Biomarker (PRD): CPA6 mRNA
Genes: CPA6; CPAH
Study 9468457 — Surrogate Endpoint (SUR): Blood pressure
Study 11171824 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18035193 — Surrogate Endpoint (SUR): Bone mineral density
Study 16303729 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9527194 — Predictive Biomarker (PRD): GRAMD4 mRNA
Genes: GRAMD4; DIP; KIAA0767
Study 30879908 — Surrogate Endpoint (SUR): Blood pressure
Study 28399624 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28399624 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11271083 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 31470599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28449232 — Predictive Biomarker (PRD): SARM1 mRNA
Genes: SARM1; KIAA0524; SAMD2; SARM
Study 26381232 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21723443 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21723443 — Surrogate Endpoint (SUR): Bone mineral density
Study 21723443 — Surrogate Endpoint (SUR): Blood pressure
Study 20017932 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2839628 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2839628 — Surrogate Endpoint (SUR): Blood pressure
Study 31870692 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15254884 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15254884 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7944835 — Surrogate Endpoint (SUR): Blood pressure
Study 30352838 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25248814 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 19883392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19883392 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19883392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16118090 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16118090 — Surrogate Endpoint (SUR): Bone mineral density
Study 20212029 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17392142 — Surrogate Endpoint (SUR): Blood pressure
Study 12488154 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 2141494 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 30398382 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 24209894 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 24209894 — Surrogate Endpoint (SUR): Serum calcium
Study 24209894 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 20881877 — Surrogate Endpoint (SUR): Blood pressure
Study 15390214 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 20844543 — Surrogate Endpoint (SUR): Blood pressure
Study 17715031 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16042670 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30965389 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 22207676 — Predictive Biomarker (PRD): ACKR1 mRNA
Genes: ACKR1; DARC; FY; GPD
Study 15889519 — Surrogate Endpoint (SUR): Blood pressure
Study 12364422 — Surrogate Endpoint (SUR): Bone mineral density
Study 12658930 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20618675 — Surrogate Endpoint (SUR): Blood pressure
Study 10519433 — Surrogate Endpoint (SUR): Blood pressure
Study 7195230 — Surrogate Endpoint (SUR): Blood pressure
Study 30921340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30921340 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18611341 — Surrogate Endpoint (SUR): Serum potassium
Study 25338198 — Predictive Biomarker (PRD): CD79A mRNA
Genes: CD79A; IGA; MB1
Study 15488878 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 15488878 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3276279 — Surrogate Endpoint (SUR): Blood pressure
Study 31657167 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 25413223 — Surrogate Endpoint (SUR): Blood pressure
Study 25413223 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11113718 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29529169 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29529169 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23190359 — Predictive Biomarker (PRD): PROCR mRNA
Genes: PROCR; EPCR
Study 12709682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12709682 — Safety Biomarker (SAF): IL-6 and IL-10
Study 8793451 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 6388897 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6388897 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8743516 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8743516 — Surrogate Endpoint (SUR): Blood pressure
Study 1656826 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1656826 — Surrogate Endpoint (SUR): Serum creatinine
Study 29261566 — Surrogate Endpoint (SUR): Blood pressure
Study 25480930 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31299655 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25904586 — Safety Biomarker (SAF): Reactive oxygen species
Study 25904586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25904586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23552179 — Surrogate Endpoint (SUR): Serum creatinine
Study 16100235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25074283 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 19732445 — Surrogate Endpoint (SUR): Bone mineral density
Study 2216994 — Surrogate Endpoint (SUR): Blood pressure
Study 26577455 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 15668637 — Safety Biomarker (SAF): Reactive oxygen species
Study 27258567 — Predictive Biomarker (PRD): NKX2-1 mRNA
Genes: NKX2-1; NKX2A; TITF1; TTF1
Study 18936475 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18936475 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14518526 — Predictive Biomarker (PRD): PCLO mRNA
Genes: PCLO; ACZ; KIAA0559
Study 29112461 — Surrogate Endpoint (SUR): Bone mineral density
Study 28290847 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21058198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15660667 — Predictive Biomarker (PRD): RGS4 mRNA
Genes: RGS4
Study 25671766 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19447425 — Surrogate Endpoint (SUR): Sperm parameters
Study 25873370 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21296768 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8154167 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 6123330 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6758746 — Surrogate Endpoint (SUR): Blood pressure
Study 29516853 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 15637138 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 15637138 — Predictive Biomarker (PRD): TAL1 mRNA
Genes: TAL1; BHLHA17; SCL; TCL5
Study 15637138 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 15637138 — Predictive Biomarker (PRD): MLLT10 mRNA
Genes: MLLT10; AF10
Study 15637138 — Predictive Biomarker (PRD): TLX1 mRNA
Genes: TLX1; HOX11; TCL3
Study 15637138 — Predictive Biomarker (PRD): TLX3 mRNA
Genes: TLX3; HOX11L2
Study 12236426 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21604824 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 19444092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17584199 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 29030456 — Surrogate Endpoint (SUR): Blood pressure
Study 18495694 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 14561241 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 14561241 — Predictive Biomarker (PRD): CYBA mRNA
Genes: CYBA
Study 9122287 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 9122287 — Surrogate Endpoint (SUR): Blood pressure
Study 26019334 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 22030228 — Surrogate Endpoint (SUR): Blood pressure
Study 22030228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10714858 — Surrogate Endpoint (SUR): Blood pressure
Study 10714858 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10516448 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10516448 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8818434 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1408685 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1408685 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 1408685 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31029534 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 24226057 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1545080 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1545080 — Surrogate Endpoint (SUR): Serum sodium
Study 30254071 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 22231041 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2271366 — Surrogate Endpoint (SUR): Blood pressure
Study 21357275 — Surrogate Endpoint (SUR): Blood pressure
Study 21357275 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17335962 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 14764129 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 3311054 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23566943 — Surrogate Endpoint (SUR): Blood pressure
Study 20931100 — Surrogate Endpoint (SUR): Blood pressure
Study 8846291 — Surrogate Endpoint (SUR): Blood pressure
Study 26901353 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 25105388 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 15115259 — Safety Biomarker (SAF): MTHFR
Study 15115259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15115259 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22099889 — Surrogate Endpoint (SUR): Blood pressure
Study 10637255 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10637255 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29094434 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29094434 — Surrogate Endpoint (SUR): Blood pressure
Study 16417414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16417414 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16417414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16417414 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 9489309 — Surrogate Endpoint (SUR): Serum creatinine
Study 22290668 — Surrogate Endpoint (SUR): Blood pressure
Study 31465307 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 18375410 — Surrogate Endpoint (SUR): Serum uric acid
Study 9129845 — Surrogate Endpoint (SUR): Blood pressure
Study 29990442 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 29934046 — Surrogate Endpoint (SUR): Sperm parameters
Study 29934046 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 25151398 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25151398 — Predictive Biomarker (PRD): ADGRE5 mRNA
Genes: ADGRE5; CD97
Study 25151398 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 18403130 — Surrogate Endpoint (SUR): Blood pressure
Study 10100083 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10100083 — Surrogate Endpoint (SUR): Blood pressure
Study 6439360 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31369593 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24172160 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22038336 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 19270108 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23141748 — Predictive Biomarker (PRD): IFIT1 mRNA
Genes: IFIT1; G10P1; IFI56; IFNAI1; ISG56
Study 23141748 — Predictive Biomarker (PRD): IFI44 mRNA
Genes: IFI44; MTAP44
Study 17160910 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17160910 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9058494 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21934521 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18600212 — Surrogate Endpoint (SUR): Blood pressure
Study 11898913 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11898913 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18532873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15378284 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8570977 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2240627 — Surrogate Endpoint (SUR): Blood pressure