TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22784287 — Safety Biomarker (SAF): Interleukin 1
Study 22784287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22784287 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19960971 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 27733248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27733248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20171784 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14694042 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 28380132 — Surrogate Endpoint (SUR): Blood pressure
Study 9317068 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 27433065 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24788377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10357730 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10357730 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8770627 — Surrogate Endpoint (SUR): Bone mineral density
Study 1963191 — Surrogate Endpoint (SUR): Blood pressure
Study 1963191 — Surrogate Endpoint (SUR): Serum creatinine
Study 15771277 — Surrogate Endpoint (SUR): Blood pressure
Study 9667257 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 9667257 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2687193 — Surrogate Endpoint (SUR): Blood pressure
Study 17639095 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17639095 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 17639095 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17639095 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 1703598 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 1703598 — Surrogate Endpoint (SUR): Blood pressure
Study 1703598 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29985679 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22247720 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22247720 — Surrogate Endpoint (SUR): Blood pressure
Study 11158416 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 27513822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23672928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 23672928 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 23672928 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 12526313 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9395275 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19491335 — Surrogate Endpoint (SUR): Blood pressure
Study 9438777 — Surrogate Endpoint (SUR): Blood pressure
Study 22790107 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 10232438 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10232438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1909086 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29958706 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 29958706 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 29958706 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 29958706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29958706 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 29958706 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19176240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1827006 — Surrogate Endpoint (SUR): Blood pressure
Study 21303402 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 21303402 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19800722 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19800722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12738464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29568771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29568771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22442168 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22442168 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18706998 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11039260 — Surrogate Endpoint (SUR): Serum calcium
Study 6394349 — Surrogate Endpoint (SUR): Blood pressure
Study 6394349 — Surrogate Endpoint (SUR): Serum potassium
Study 23776431 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 31551206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17389707 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17389707 — Predictive Biomarker (PRD): PDE3B mRNA
Genes: PDE3B
Study 17389707 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 15466769 — Surrogate Endpoint (SUR): Blood pressure
Study 27200393 — Predictive Biomarker (PRD): RHOJ mRNA
Genes: RHOJ; ARHJ; RASL7B; RHOI; TCL
Study 22330964 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9880379 — Surrogate Endpoint (SUR): Blood pressure
Study 1771216 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31977634 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28855077 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 28855077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28855077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26159458 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 26159458 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 19329835 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 11444081 — Surrogate Endpoint (SUR): Bone mineral density
Study 31348334 — Safety Biomarker (SAF): Hyaluronic acid
Study 28524025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28524025 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28524025 — Safety Biomarker (SAF): IL-6 and IL-10
Study 30395878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30395878 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15635849 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9205634 — Surrogate Endpoint (SUR): Bone mineral density
Study 27686002 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 18485668 — Surrogate Endpoint (SUR): Blood pressure
Study 18485668 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29122253 — Surrogate Endpoint (SUR): Blood pressure
Study 15599677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11310517 — Surrogate Endpoint (SUR): Blood pressure
Study 9636952 — Surrogate Endpoint (SUR): Bone mineral density
Study 2765272 — Surrogate Endpoint (SUR): Blood pressure
Study 27888416 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 23759474 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 21683485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21683485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23650301 — Surrogate Endpoint (SUR): Blood pressure
Study 19149837 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19149837 — Surrogate Endpoint (SUR): Blood pressure
Study 17017752 — Surrogate Endpoint (SUR): Blood pressure
Study 17017752 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23279918 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 9760818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7533224 — Surrogate Endpoint (SUR): Blood pressure
Study 29193419 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 29193419 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 23278371 — Predictive Biomarker (PRD): MLXIP mRNA
Genes: MLXIP; BHLHE36; KIAA0867; MIR; MONDOA
Study 17434171 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16868496 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8712737 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1781870 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21543293 — Surrogate Endpoint (SUR): Blood pressure
Study 16508254 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 11126172 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 3490992 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3490992 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24941835 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 24941835 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24941835 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22512510 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 18254721 — Surrogate Endpoint (SUR): Blood pressure
Study 24937510 — Surrogate Endpoint (SUR): Blood pressure
Study 20499203 — Predictive Biomarker (PRD): PDPR mRNA
Genes: PDPR; KIAA1990
Study 9052357 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3670227 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31373922 — Surrogate Endpoint (SUR): Blood pressure
Study 21948782 — Surrogate Endpoint (SUR): Blood pressure
Study 25190051 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 14679153 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29121979 — Predictive Biomarker (PRD): PSD4 mRNA
Genes: PSD4; EFA6B; TIC
Study 21251179 — Surrogate Endpoint (SUR): Blood pressure
Study 15034229 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 26561314 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 18721739 — Surrogate Endpoint (SUR): Blood pressure
Study 18721739 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11039742 — Surrogate Endpoint (SUR): Blood pressure
Study 4035232 — Surrogate Endpoint (SUR): Blood pressure
Study 30021886 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30021886 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30021886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 30021886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 30021886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 30641625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30641625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30641625 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 20173020 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20173020 — Surrogate Endpoint (SUR): Blood pressure
Study 20173020 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20173020 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12443837 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12443837 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2571203 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23060056 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 21903774 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21903774 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 12862201 — Surrogate Endpoint (SUR): Blood pressure
Study 12862201 — Surrogate Endpoint (SUR): Serum hemoglobin A1C
Study 24389520 — Surrogate Endpoint (SUR): Blood pressure
Study 11187868 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 11187868 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 28201994 — Surrogate Endpoint (SUR): Bone mineral density
Study 30105266 — Safety Biomarker (SAF): Interleukin 1
Study 30105266 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 26653067 — Surrogate Endpoint (SUR): Blood pressure
Study 20121764 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7023522 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7023522 — Surrogate Endpoint (SUR): Blood pressure
Study 29935595 — Predictive Biomarker (PRD): CHRM3 mRNA
Genes: CHRM3
Study 20619512 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 25934044 — Monitoring Biomarker (MOI): Procalcitonin
Study 10359410 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1850691 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6121836 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23054802 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 8294618 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 18469237 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18469237 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17472154 — Surrogate Endpoint (SUR): Blood pressure
Study 16388166 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16388166 — Surrogate Endpoint (SUR): Blood pressure
Study 31584516 — Surrogate Endpoint (SUR): Blood pressure
Study 26626993 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26626993 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 26626993 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 26626993 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 26626993 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 25574674 — Surrogate Endpoint (SUR): Bone mineral density
Study 22716474 — Predictive Biomarker (PRD): NRXN3 mRNA
Genes: NRXN3; KIAA0743
Study 20401289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 6088019 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 27656953 — Surrogate Endpoint (SUR): Blood pressure
Study 21040410 — Monitoring Biomarker (MOI): HBV DNA
Study 12237663 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12237663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 28000620 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 20144207 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 20144207 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18194848 — Predictive Biomarker (PRD): POLI mRNA
Genes: POLI; RAD30B
Study 15938033 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 15938033 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12736473 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24857051 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9799980 — Surrogate Endpoint (SUR): Blood pressure
Study 30657120 — Surrogate Endpoint (SUR): Blood pressure
Study 26123919 — Surrogate Endpoint (SUR): Bone mineral density
Study 19594864 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23350342 — Surrogate Endpoint (SUR): Bone mineral density
Study 12441260 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 12441260 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 10515844 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1723464 — Surrogate Endpoint (SUR): Blood pressure
Study 27930529 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24584549 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24584549 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15763054 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15763054 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12428174 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28028150 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 10418043 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31863599 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31863599 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 27779456 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27779456 — Surrogate Endpoint (SUR): Blood pressure
Study 7986467 — Surrogate Endpoint (SUR): Blood pressure
Study 26296647 — Surrogate Endpoint (SUR): Blood pressure
Study 30067600 — Surrogate Endpoint (SUR): Bone mineral density
Study 19422355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2872717 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30124726 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 26795846 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26795846 — Safety Biomarker (SAF): BDNF
Study 20890191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20890191 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 20890191 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20890191 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20890191 — Safety Biomarker (SAF): Interleukin 12
Study 20890191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16194413 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16194413 — Surrogate Endpoint (SUR): Serum creatinine
Study 16194413 — Surrogate Endpoint (SUR): Blood pressure
Study 2983910 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30245755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30245755 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 30245755 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30245755 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 24903081 — Surrogate Endpoint (SUR): Blood pressure
Study 20145666 — Surrogate Endpoint (SUR): Blood pressure
Study 10486663 — Surrogate Endpoint (SUR): Blood pressure
Study 29953482 — Safety Biomarker (SAF): RYR1
Genes: RYR; PPP1R137
Study 22797934 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 2392791 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28574408 — Surrogate Endpoint (SUR): Bone mineral density
Study 21441444 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21441444 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17275744 — Surrogate Endpoint (SUR): Blood pressure
Study 11730653 — Surrogate Endpoint (SUR): Blood pressure
Study 28959813 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18787327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16669846 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12797494 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 12797494 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31113362 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 15675575 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2206036 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2206036 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28768451 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 23415311 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23459334 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12631051 — Surrogate Endpoint (SUR): Blood pressure
Study 10671927 — Surrogate Endpoint (SUR): Blood pressure
Study 4030197 — Surrogate Endpoint (SUR): Blood pressure
Study 18508946 — Surrogate Endpoint (SUR): Serum creatinine
Study 2647051 — Surrogate Endpoint (SUR): Blood pressure
Study 25450818 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 25450818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16948809 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11380515 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein