TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19014354 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 19014354 — Surrogate Endpoint (SUR): Blood pressure
Study 19014354 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11451621 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7872725 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22109683 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 18543381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6176796 — Surrogate Endpoint (SUR): Blood pressure
Study 31189759 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31189759 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31437816 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31437816 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 24249423 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 9716580 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 22431170 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 9540946 — Surrogate Endpoint (SUR): Blood pressure
Study 25034935 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25034935 — Surrogate Endpoint (SUR): Blood pressure
Study 9258175 — Predictive Biomarker (PRD): MEOX2 mRNA
Genes: MEOX2; GAX; MOX2
Study 3333524 — Surrogate Endpoint (SUR): Blood pressure
Study 19401423 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19401423 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3537248 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29068453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29068453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29068453 — Safety Biomarker (SAF): IL-6 and IL-10
Study 26846284 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 18596740 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 8523873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8523873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8523873 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8523873 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 24326088 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 24326088 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study 12843357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1704026 — Surrogate Endpoint (SUR): Blood pressure
Study 24642950 — Surrogate Endpoint (SUR): Blood pressure
Study 24642950 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20694731 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12644728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 4077795 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20086031 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20086031 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18044335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19283886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 25299740 — Safety Biomarker (SAF): Hyaluronic acid
Study 7939468 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 7939468 — Surrogate Endpoint (SUR): Serum testosterone
Study 21742071 — Surrogate Endpoint (SUR): Serum calcium
Study 15308882 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15308882 — Surrogate Endpoint (SUR): Blood pressure
Study 11787984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8311225 — Surrogate Endpoint (SUR): Blood pressure
Study 3291161 — Predictive Biomarker (PRD): LUM mRNA
Genes: LUM; LDC; SLRR2D
Study 30791747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30791747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30791747 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24157403 — Surrogate Endpoint (SUR): Bone mineral density
Study 10957752 — Surrogate Endpoint (SUR): Bone mineral density
Study 10957752 — Surrogate Endpoint (SUR): Blood pressure
Study 3914075 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 19250841 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 11715158 — Surrogate Endpoint (SUR): Blood pressure
Study 9138166 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9138166 — Predictive Biomarker (PRD): BRCA2
Genes: FAD; FAD1; BRCC2; XRCC11
Study 22018129 — Predictive Biomarker (PRD): NDC80 mRNA
Genes: NDC80; HEC; HEC1; KNTC2
Study 22018129 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 22018129 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 22018129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11369167 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9398695 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31073087 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23515219 — Surrogate Endpoint (SUR): Blood pressure
Study 15585624 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15585624 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11322841 — Surrogate Endpoint (SUR): Blood pressure
Study 9032045 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9032045 — Surrogate Endpoint (SUR): Blood pressure
Study 29631804 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 27602906 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 16109780 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 10399791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19960970 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 11585356 — Surrogate Endpoint (SUR): Serum calcium
Study 31125274 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 26892777 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 26892777 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 26892777 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 26892777 — Predictive Biomarker (PRD): NR1I2 mRNA
Genes: NR1I2; PXR
Study 16272960 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 16272960 — Predictive Biomarker (PRD): GRIN1 mRNA
Genes: GRIN1; NMDAR1
Study 24144222 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 20350170 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 16752282 — Surrogate Endpoint (SUR): Bone mineral density
Study 9052578 — Surrogate Endpoint (SUR): Bone mineral density
Study 22525670 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 20036404 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7588925 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30955912 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 26141263 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 21321461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17257478 — Surrogate Endpoint (SUR): Blood pressure
Study 11508581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11508581 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11508581 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2825820 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20028728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12627998 — Surrogate Endpoint (SUR): Blood pressure
Study 31222044 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31222044 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31313548 — Surrogate Endpoint (SUR): Blood pressure
Study 22282500 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22282500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22282500 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22282500 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 22282500 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 17324657 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 17324657 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 28437278 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28437278 — Surrogate Endpoint (SUR): Blood pressure
Study 16818564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25029426 — Surrogate Endpoint (SUR): Blood pressure
Study 25029426 — Surrogate Endpoint (SUR): Serum potassium
Study 11247198 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 31387629 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28862373 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18260172 — Surrogate Endpoint (SUR): Bone mineral density
Study 15639293 — Monitoring Biomarker (MOI): HBV DNA
Study 12189483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12189483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2140160 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21275446 — Surrogate Endpoint (SUR): Blood pressure
Study 16406239 — Predictive Biomarker (PRD): GJB2 mRNA
Genes: GJB2
Study 16406239 — Predictive Biomarker (PRD): GJB3 mRNA
Genes: GJB3; CX31
Study 16406239 — Predictive Biomarker (PRD): GJB6 mRNA
Genes: GJB6
Study 9018183 — Surrogate Endpoint (SUR): Blood pressure
Study 29419875 — Predictive Biomarker (PRD): KIR2DL4 mRNA
Genes: KIR2DL4; CD158D; KIR103AS
Study 27512827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20728875 — Predictive Biomarker (PRD): CHRNA7 mRNA
Genes: CHRNA7; NACHRA7
Study 22019438 — Surrogate Endpoint (SUR): Blood pressure
Study 10787430 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10787430 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15913168 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 9579503 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28804801 — Predictive Biomarker (PRD): INA mRNA
Genes: INA; NEF5
Study 24698195 — Surrogate Endpoint (SUR): Serum creatinine
Study 19058059 — Surrogate Endpoint (SUR): Bone mineral density
Study 8195853 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 19651631 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29750828 — Surrogate Endpoint (SUR): Bone mineral density
Study 23403530 — Surrogate Endpoint (SUR): Bone mineral density
Study 20516425 — Surrogate Endpoint (SUR): Blood pressure
Study 6784976 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 6784976 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 6784976 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31711489 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 20813019 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12500883 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2715089 — Surrogate Endpoint (SUR): Blood pressure
Study 25037854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19256180 — Surrogate Endpoint (SUR): Blood pressure
Study 27793125 — Surrogate Endpoint (SUR): Bone mineral density
Study 10464529 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1867297 — Surrogate Endpoint (SUR): Serum creatinine
Study 28266821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8217026 — Surrogate Endpoint (SUR): Blood pressure
Study 29700636 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 24925270 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 24925270 — Surrogate Endpoint (SUR): Blood pressure
Study 24925270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24925270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20724431 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31427688 — Surrogate Endpoint (SUR): Serum creatinine
Study 22588803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22588803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22588803 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22588803 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9920138 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28385185 — Safety Biomarker (SAF): HLA-DQA1
Genes: CELIAC1
Study 6872409 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6872409 — Surrogate Endpoint (SUR): Blood pressure
Study 20863238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12756020 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8797150 — Surrogate Endpoint (SUR): Blood pressure
Study 22435948 — Surrogate Endpoint (SUR): Serum creatinine
Study 22435948 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16186073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16186073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9074912 — Surrogate Endpoint (SUR): Blood pressure
Study 15847101 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30615007 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30983008 — Predictive Biomarker (PRD): CLEC4D mRNA
Genes: CLEC4D; CLECSF8; MCL
Study 22046271 — Surrogate Endpoint (SUR): Blood pressure
Study 21317165 — Surrogate Endpoint (SUR): Blood pressure
Study 18835434 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18835434 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9268221 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9268221 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 19804570 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15905896 — Surrogate Endpoint (SUR): Blood pressure
Study 8733437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27958220 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 20175014 — Surrogate Endpoint (SUR): Blood pressure
Study 10533471 — Predictive Biomarker (PRD): MGAM mRNA
Genes: MGAM; MGA; MGAML
Study 19703819 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18025296 — Surrogate Endpoint (SUR): Blood pressure
Study 11038407 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 24132900 — Predictive Biomarker (PRD): CHN2 mRNA
Genes: CHN2; ARHGAP3; BCH
Study 24132900 — Predictive Biomarker (PRD): CPVL mRNA
Genes: CPVL; VLP; PSEC0124; UNQ197/PRO223
Study 24132900 — Predictive Biomarker (PRD): COL21A1 mRNA
Genes: COL21A1; COL1AL; FP633
Study 24132900 — Predictive Biomarker (PRD): PYGL mRNA
Genes: PYGL
Study 24132900 — Predictive Biomarker (PRD): TRIM9 mRNA
Genes: TRIM9; KIAA0282; RNF91
Study 12709127 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 15462690 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15462690 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15462690 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8390369 — Surrogate Endpoint (SUR): Blood pressure
Study 22774206 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2193318 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 9772944 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9772944 — Surrogate Endpoint (SUR): Blood pressure
Study 26797697 — Safety Biomarker (SAF): Hyaluronic acid
Study 26797697 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18676693 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 19489494 — Surrogate Endpoint (SUR): Serum uric acid
Study 12527970 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 12527970 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 12527970 — Predictive Biomarker (PRD): PSMA1 mRNA
Genes: PSMA1; HC2; NU; PROS30; PSC2
Study 27596132 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27596132 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11830339 — Monitoring Biomarker (MOI): HBV DNA
Study 23911864 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 23911864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23911864 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 23911864 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15250255 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15250255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15250255 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15250255 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15250255 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9315414 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27572290 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21878082 — Surrogate Endpoint (SUR): Blood pressure
Study 19407662 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 14871464 — Surrogate Endpoint (SUR): Bone mineral density
Study 11728960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11728960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9210707 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25641242 — Surrogate Endpoint (SUR): Blood pressure
Study 16669959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11728290 — Surrogate Endpoint (SUR): Blood pressure
Study 8126257 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 8126257 — Surrogate Endpoint (SUR): Serum potassium
Study 8126257 — Surrogate Endpoint (SUR): Serum sodium
Study 3110681 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29618011 — Surrogate Endpoint (SUR): Blood pressure
Study 28589493 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12554889 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24048485 — Surrogate Endpoint (SUR): Blood pressure
Study 18388881 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 9814476 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9814476 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ESR1 mRNA
Genes: ESR1; ESR; NR3A1
Study 2802123 — Surrogate Endpoint (SUR): Blood pressure
Study 26222559 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 21875546 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18001802 — Surrogate Endpoint (SUR): Bone mineral density
Study 8443481 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 8443481 — Surrogate Endpoint (SUR): Blood pressure
Study 29792287 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18927301 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18927301 — Predictive Biomarker (PRD): NDRG1 mRNA
Genes: NDRG1; CAP43; DRG1; RTP
Study 18927301 — Predictive Biomarker (PRD): SLC7A5 mRNA
Genes: SLC7A5; CD98LC; LAT1; MPE16
Study 18927301 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 18927301 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1472833 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26850265 — Surrogate Endpoint (SUR): Bone mineral density
Study 2169371 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27770279 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24035872 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 19132882 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31256036 — Safety Biomarker (SAF): Human leucocyte antigen
Study 28291622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25735400 — Surrogate Endpoint (SUR): Blood pressure
Study 23267856 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219