TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12411644 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 12411644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 357455 — Surrogate Endpoint (SUR): Blood pressure
Study 27838874 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28270498 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 11558484 — Surrogate Endpoint (SUR): Blood pressure
Study 11558484 — Surrogate Endpoint (SUR): Serum creatinine
Study 11558484 — Surrogate Endpoint (SUR): Serum uric acid
Study 27428476 — Safety Biomarker (SAF): BDNF
Study 21138476 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 21138476 — Surrogate Endpoint (SUR): Blood pressure
Study 21138476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21138476 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21138476 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12913035 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8095779 — Surrogate Endpoint (SUR): Blood pressure
Study 30825525 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27001189 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20810159 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 7780057 — Surrogate Endpoint (SUR): Blood pressure
Study 6244198 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10578225 — Surrogate Endpoint (SUR): Blood pressure
Study 10578225 — Surrogate Endpoint (SUR): Serum uric acid
Study 31600397 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 31600397 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28391289 — Surrogate Endpoint (SUR): Blood pressure
Study 6373154 — Surrogate Endpoint (SUR): Blood pressure
Study 28033279 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 20833658 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 18821668 — Surrogate Endpoint (SUR): Serum calcium
Study 2217349 — Surrogate Endpoint (SUR): Blood pressure
Study 11350752 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9036201 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8373897 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29302744 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 18192897 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 18192897 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 18192897 — Predictive Biomarker (PRD): IL18RAP mRNA
Genes: IL18RAP; IL1R7
Study 18192897 — Predictive Biomarker (PRD): FCGR2A mRNA
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 18192897 — Predictive Biomarker (PRD): PGGT1B mRNA
Genes: PGGT1B
Study 8792796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6486124 — Surrogate Endpoint (SUR): Blood pressure
Study 29940668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29940668 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16325968 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 3080101 — Surrogate Endpoint (SUR): Blood pressure
Study 3080101 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 9008243 — Surrogate Endpoint (SUR): Blood pressure
Study 3549757 — Surrogate Endpoint (SUR): Blood pressure
Study 24034658 — Surrogate Endpoint (SUR): Blood pressure
Study 12947433 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21419560 — Surrogate Endpoint (SUR): Blood pressure
Study 26979712 — Surrogate Endpoint (SUR): Blood pressure
Study 30595323 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 30595323 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30595323 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25039318 — Safety Biomarker (SAF): Interleukin 1
Study 15755829 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 14749241 — Surrogate Endpoint (SUR): Bone mineral density
Study 29518432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29518432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29518432 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 16620333 — Predictive Biomarker (PRD): KY mRNA
Genes: KY
Study 517118 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27379904 — Surrogate Endpoint (SUR): Blood pressure
Study 18812659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1976052 — Surrogate Endpoint (SUR): Blood pressure
Study 24989688 — Predictive Biomarker (PRD): CCL26 mRNA
Genes: CCL26; SCYA26; UNQ216/PRO242
Study 24989688 — Predictive Biomarker (PRD): CCL24 mRNA
Genes: CCL24; MPIF2; SCYA24
Study 17644475 — Surrogate Endpoint (SUR): Blood pressure
Study 26338890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26338890 — Surrogate Endpoint (SUR): Blood pressure
Study 23670706 — Predictive Biomarker (PRD): BCL2L1 mRNA
Genes: BCL2L1; BCL2L; BCLX
Study 21516368 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21516368 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 29615049 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 23279603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29090731 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 21088973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21088973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11513305 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8582131 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 645073 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 23053764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21739205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16728551 — Surrogate Endpoint (SUR): Blood pressure
Study 10938022 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10938022 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10938022 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30038151 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 18487744 — Predictive Biomarker (PRD): PPP6R2 mRNA
Genes: PPP6R2; KIAA0685; PP6R2; SAPS2
Study 7868973 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28899735 — Surrogate Endpoint (SUR): Blood pressure
Study 1495748 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23445797 — Surrogate Endpoint (SUR): Blood pressure
Study 17522901 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 11424663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6501724 — Surrogate Endpoint (SUR): Blood pressure
Study 24213914 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 24213914 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 16758243 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16758243 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 24591191 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12467997 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 31801712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31801712 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31801712 — Surrogate Endpoint (SUR): Serum creatinine
Study 31801712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25291499 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25291499 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25291499 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21798658 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 18465191 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31395505 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31395505 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19537837 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19537837 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15175438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15175438 — Surrogate Endpoint (SUR): Blood pressure
Study 15175438 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27596801 — Predictive Biomarker (PRD): LSP1 mRNA
Genes: LSP1; WP34
Study 27596801 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 27596801 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 22385118 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 22385118 — Surrogate Endpoint (SUR): Serum testosterone
Study 8655902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17935933 — Surrogate Endpoint (SUR): Blood pressure
Study 31581926 — Surrogate Endpoint (SUR): Blood pressure
Study 31581926 — Surrogate Endpoint (SUR): Serum creatinine
Study 26092821 — Surrogate Endpoint (SUR): Blood pressure
Study 15677573 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 8767528 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 27634557 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25942487 — Surrogate Endpoint (SUR): Blood pressure
Study 25942487 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25882910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19415820 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 19415820 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 19415820 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 19415820 — Predictive Biomarker (PRD): F12 mRNA
Genes: F12
Study 8553675 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 8553675 — Surrogate Endpoint (SUR): Blood pressure
Study 12715685 — Surrogate Endpoint (SUR): Blood pressure
Study 30541065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17609490 — Surrogate Endpoint (SUR): Blood pressure
Study 23282123 — Surrogate Endpoint (SUR): Blood pressure
Study 12751337 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3371847 — Monitoring Biomarker (MOI): HBV DNA
Study 11948038 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11948038 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22480275 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 7715294 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29493163 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23328126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23328126 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21806837 — Surrogate Endpoint (SUR): Bone mineral density
Study 19836709 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17086021 — Surrogate Endpoint (SUR): Blood pressure
Study 17086021 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9661649 — Predictive Biomarker (PRD): CYP21A2 mRNA
Genes: CYP21A2; CYP21; CYP21B
Study 22691828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20831680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20831680 — Surrogate Endpoint (SUR): Blood pressure
Study 20831680 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20831680 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20831680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20831680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1382539 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29746294 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29746294 — Surrogate Endpoint (SUR): Bone mineral density
Study 29746294 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 23924587 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23924587 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 8973871 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24478399 — Safety Biomarker (SAF): miR-140
Genes: MIR140
Study 24478399 — Safety Biomarker (SAF): miR-142
Genes: MIR142
Study 24478399 — Safety Biomarker (SAF): miR-423
Genes: MIR423
Study 24478399 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study 24478399 — Safety Biomarker (SAF): miR-192
Genes: MIR192
Study 24478399 — Monitoring Biomarker (MOI): miR-195-5p
Genes: MIR195
Study 16248984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8789468 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8789468 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 22271868 — Surrogate Endpoint (SUR): Blood pressure
Study 19934286 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 19934286 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 14660044 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 8251901 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2871185 — Surrogate Endpoint (SUR): Blood pressure
Study 22016263 — Surrogate Endpoint (SUR): Blood pressure
Study 18360186 — Surrogate Endpoint (SUR): Blood pressure
Study 8620703 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 31526108 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31526108 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21163806 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 7703623 — Surrogate Endpoint (SUR): Bone mineral density
Study 1064725 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 31392401 — Surrogate Endpoint (SUR): Bone mineral density
Study 28290296 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20137594 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20137594 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 25977995 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23908160 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10918945 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10918945 — Surrogate Endpoint (SUR): Blood pressure
Study 9405898 — Surrogate Endpoint (SUR): Blood pressure
Study 20825715 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 16988134 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31732180 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 10730531 — Surrogate Endpoint (SUR): Serum creatinine
Study 8602477 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 1974628 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31559410 — Surrogate Endpoint (SUR): Blood pressure
Study 22958738 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17970234 — Surrogate Endpoint (SUR): Serum creatinine
Study 17970234 — Surrogate Endpoint (SUR): Serum uric acid
Study 6158263 — Predictive Biomarker (PRD): NAPA mRNA
Genes: NAPA; SNAPA
Study 26885107 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 26885107 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26885107 — Surrogate Endpoint (SUR): Serum creatinine
Study 19576320 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10720518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10720518 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10720518 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9167106 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26970335 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 20608895 — Surrogate Endpoint (SUR): Blood pressure
Study 15255625 — Surrogate Endpoint (SUR): Blood pressure
Study 10682127 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1747216 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1747216 — Surrogate Endpoint (SUR): Blood pressure
Study 31161498 — Surrogate Endpoint (SUR): Blood pressure
Study 10543293 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7818568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7818568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7818568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2678231 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30175433 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 24287284 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16088423 — Surrogate Endpoint (SUR): Serum calcium
Study 7788147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7788147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31298333 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 11074738 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11074738 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8873543 — Surrogate Endpoint (SUR): Blood pressure
Study 4016786 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31551218 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 25348087 — Safety Biomarker (SAF): Hyaluronic acid
Study 28904172 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 9187023 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 8387806 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8387806 — Surrogate Endpoint (SUR): Blood pressure
Study 25033066 — Surrogate Endpoint (SUR): Bone mineral density
Study 22735163 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22735163 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26496265 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19604522 — Surrogate Endpoint (SUR): Blood pressure
Study 19604522 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28075147 — Surrogate Endpoint (SUR): Blood pressure
Study 9244210 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9244210 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2244446 — Surrogate Endpoint (SUR): Blood pressure
Study 30058959 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 20083961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20083961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17340137 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17340137 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17340137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 17340137 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study 17340137 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 17340137 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 17340137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10218737 — Surrogate Endpoint (SUR): Blood pressure
Study 6354385 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 25393645 — Surrogate Endpoint (SUR): Bone mineral density
Study 11704092 — Surrogate Endpoint (SUR): Blood pressure
Study 10719133 — Surrogate Endpoint (SUR): Blood pressure
Study 22339105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22339105 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21519296 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8752162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8752162 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 6323185 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1