TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25592188 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 25592188 — Surrogate Endpoint (SUR): Blood pressure
Study 21075062 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15724223 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9475269 — Surrogate Endpoint (SUR): Blood pressure
Study 7609572 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9580255 — Monitoring Biomarker (MOI): HBV DNA
Study 25891173 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 10599981 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 10599981 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 29275344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29275344 — Surrogate Endpoint (SUR): Blood pressure
Study 19525856 — Surrogate Endpoint (SUR): Blood pressure
Study 18163098 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 9509973 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 14531810 — Surrogate Endpoint (SUR): Blood pressure
Study 9013470 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9013470 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3698464 — Surrogate Endpoint (SUR): Blood pressure
Study 29652758 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28915853 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study 25325208 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25325208 — Surrogate Endpoint (SUR): Serum creatinine
Study 14512205 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 1627434 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22443213 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11600576 — Predictive Biomarker (PRD); Safety Biomarker (SAF): OPN mRNA
Genes: SPP1; BNSP; OPN; PSEC0156
Study 11600576 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22592586 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15772332 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20495811 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 15963359 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9671874 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31305329 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 23173252 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 11181472 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29276925 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26193177 — Surrogate Endpoint (SUR): Bone mineral density
Study 8677916 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1848618 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22455413 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 6407500 — Surrogate Endpoint (SUR): Blood pressure
Study 31320597 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 23257033 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27179167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28774367 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28774367 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 3884627 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30285187 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30285187 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25975643 — Surrogate Endpoint (SUR): Pathological complete response
Study 11778969 — Surrogate Endpoint (SUR): Serum creatinine
Study 11778969 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20478865 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16209246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16209246 — Safety Biomarker (SAF): Interleukin 1
Study 10800498 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24935230 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 24935230 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20060711 — Predictive Biomarker (PRD): Hormone receptor
Study 18337008 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 11965831 — Surrogate Endpoint (SUR): Blood pressure
Study 1922250 — Surrogate Endpoint (SUR): Blood pressure
Study 28327089 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15469788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15469788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11567815 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9586915 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31420057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25733157 — Predictive Biomarker (PRD): ISG15 mRNA
Genes: ISG15; G1P2; UCRP
Study 25733157 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25733157 — Monitoring Biomarker (MOI): HBV DNA
Study 9346275 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27547135 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25911076 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8060544 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3051873 — Surrogate Endpoint (SUR): Blood pressure
Study 25014687 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 6937648 — Surrogate Endpoint (SUR): Blood pressure
Study 28710178 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 28710178 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28710178 — Surrogate Endpoint (SUR): Blood pressure
Study 26051571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26051571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26051571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26051571 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15289213 — Surrogate Endpoint (SUR): Blood pressure
Study 11450766 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9389781 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9389781 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28893921 — Surrogate Endpoint (SUR): Serum potassium
Study 25851691 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8297222 — Surrogate Endpoint (SUR): Blood pressure
Study 31315908 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 26026502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19752340 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 11199954 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 226840 — Surrogate Endpoint (SUR): Blood pressure
Study 28715286 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 22568247 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 17469006 — Surrogate Endpoint (SUR): Blood pressure
Study 7529535 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1164007 — Surrogate Endpoint (SUR): Serum creatinine
Study 17255126 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17255126 — Surrogate Endpoint (SUR): Serum potassium
Study 3169112 — Surrogate Endpoint (SUR): Blood pressure
Study 30047573 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 30047573 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14872246 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14872246 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 14872246 — Surrogate Endpoint (SUR): Blood pressure
Study 8305412 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 8305412 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26370445 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3733491 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8230572 — Surrogate Endpoint (SUR): Blood pressure
Study 26447668 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21041914 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16808310 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16808310 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 3389898 — Surrogate Endpoint (SUR): Blood pressure
Study 354829 — Surrogate Endpoint (SUR): Blood pressure
Study 354829 — Surrogate Endpoint (SUR): Serum creatinine
Study 26360837 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 26360837 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26360837 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21339244 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 30578013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24220555 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 7868799 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7868799 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7868799 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 21296694 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15254792 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 8257887 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25457929 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 20605499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20605499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20605499 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8950072 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8950072 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28732480 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 28732480 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 2340210 — Surrogate Endpoint (SUR): Blood pressure
Study 31915163 — Predictive Biomarker (PRD): CSAD mRNA
Genes: CSAD; CSD
Study 19291119 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17522570 — Surrogate Endpoint (SUR): Blood pressure
Study 11788176 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9711425 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9711425 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2731120 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19776222 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 19776222 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30120069 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 26980389 — Safety Biomarker (SAF): Hyaluronic acid
Study 10817585 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22251483 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 22251483 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 16332666 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17914032 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9274891 — Surrogate Endpoint (SUR): Bone mineral density
Study 23715754 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 10526701 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7795096 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22934858 — Predictive Biomarker (PRD): XCL1 mRNA
Genes: XCL1; LTN; SCYC1
Study 19900154 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 10636271 — Surrogate Endpoint (SUR): Blood pressure
Study 29322610 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24697877 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24697877 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24697877 — Surrogate Endpoint (SUR): Blood pressure
Study 12795771 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25450583 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 12592333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1860749 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24837306 — Surrogate Endpoint (SUR): Bone mineral density
Study 8758833 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8758833 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 2523770 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16416230 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25893930 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 25893930 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study 25893930 — Monitoring Biomarker (MOI): miR-92a-3p
Study 9125276 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 25549192 — Surrogate Endpoint (SUR): Blood pressure
Study 22179601 — Surrogate Endpoint (SUR): Blood pressure
Study 17364234 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 8560901 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3389862 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 31407230 — Predictive Biomarker (PRD): FAT3 mRNA
Genes: FAT3; CDHF15; KIAA1989
Study 31407230 — Predictive Biomarker (PRD): PKHD1 mRNA
Genes: PKHD1; FCYT; TIGM1
Study 31407230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 31407230 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 31407230 — Predictive Biomarker (PRD): PARP4 mRNA
Genes: PARP4; ADPRTL1; KIAA0177; PARPL
Study 31407230 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 21381497 — Safety Biomarker (SAF): Hyaluronic acid
Study 27384040 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17379017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17379017 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 3056085 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 3056085 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 28619175 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 25877694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18710330 — Surrogate Endpoint (SUR): Blood pressure
Study 8903382 — Safety Biomarker (SAF): Hyaluronic acid
Study 27083135 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25096822 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 12460330 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12460330 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2174320 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30709694 — Surrogate Endpoint (SUR): Probing pocket depth
Study 20517667 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20517667 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22104363 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15918104 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15918104 — Surrogate Endpoint (SUR): Blood pressure
Study 8769362 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22297666 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22297666 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10811588 — Surrogate Endpoint (SUR): Blood pressure
Study 10969367 — Surrogate Endpoint (SUR): Blood pressure
Study 3534592 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29198406 — Surrogate Endpoint (SUR): Blood pressure
Study 8717532 — Surrogate Endpoint (SUR): Bone mineral density
Study 23552126 — Surrogate Endpoint (SUR): Blood pressure
Study 19555390 — Predictive Biomarker (PRD): CLDN4 mRNA
Genes: CLDN4; CPER; CPETR1; WBSCR8
Study 19555390 — Predictive Biomarker (PRD): CLDN3 mRNA
Genes: CLDN3; C7orf1; CPETR2
Study 11474160 — Surrogate Endpoint (SUR): Blood pressure
Study 8574271 — Surrogate Endpoint (SUR): Serum testosterone
Study 8574271 — Surrogate Endpoint (SUR): Blood pressure
Study 2159509 — Surrogate Endpoint (SUR): Blood pressure
Study 31272550 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31272550 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 14607455 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 14607455 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 14607455 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20728210 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20129212 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10567956 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1751794 — Surrogate Endpoint (SUR): Blood pressure
Study 21380536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19056656 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17888974 — Predictive Biomarker (PRD): CSAD mRNA
Genes: CSAD; CSD
Study 28800765 — Surrogate Endpoint (SUR): Blood pressure
Study 18093792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18093792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18093792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6361299 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29258367 — Surrogate Endpoint (SUR): Serum testosterone
Study 29258367 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26606967 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9356538 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 25266547 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20067654 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20067654 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1906893 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 21971406 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 11575229 — Surrogate Endpoint (SUR): Blood pressure
Study 26966279 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 26966279 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25955191 — Surrogate Endpoint (SUR): Blood pressure
Study 23509106 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22321227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22321227 — Surrogate Endpoint (SUR): Serum creatinine
Study 22321227 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19382480 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 27160157 — Predictive Biomarker (PRD): SEPTIN3 mRNA
Genes: SEPTIN3; SEP3; SEPT3
Study 25403606 — Surrogate Endpoint (SUR): Blood pressure
Study 19280097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19280097 — Surrogate Endpoint (SUR): Bone mineral density
Study 19280097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26497961 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18506924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18506924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17323614 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17077322 — Predictive Biomarker (PRD): SERPINB9 mRNA
Genes: SERPINB9; PI9
Study 17077322 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 30005743 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30005743 — Surrogate Endpoint (SUR): Blood pressure
Study 26759468 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23594858 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23594858 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 20873905 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 9190980 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 27154357 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4