TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9823478 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19897470 — Surrogate Endpoint (SUR): Blood pressure
Study 19453396 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27005463 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 27005463 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 6128451 — Surrogate Endpoint (SUR): Blood pressure
Study 22526529 — Surrogate Endpoint (SUR): Blood pressure
Study 1847023 — Surrogate Endpoint (SUR): Blood pressure
Study 1847023 — Safety Biomarker (SAF): 51Cr-EDTA
Study 24572590 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22525773 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22525773 — Surrogate Endpoint (SUR): Blood pressure
Study 15760426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15760426 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12409657 — Surrogate Endpoint (SUR): Serum calcium
Study 26659706 — Predictive Biomarker (PRD): BOC mRNA
Genes: BOC; UNQ604/PRO1190
Study 10550566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29469022 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 29469022 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 17492590 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 16198334 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12195347 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12195347 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 12195347 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31671060 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20154213 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18277935 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10534084 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 27080315 — Surrogate Endpoint (SUR): Blood pressure
Study 8897029 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8897029 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10234493 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6261607 — Surrogate Endpoint (SUR): Serum potassium
Study 17848425 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15250199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15250199 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15250199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12583341 — Monitoring Biomarker (MOI): HBV DNA
Study 29089370 — Surrogate Endpoint (SUR): Blood pressure
Study 18516457 — Surrogate Endpoint (SUR): Blood pressure
Study 18516457 — Surrogate Endpoint (SUR): Serum sodium
Study 18516457 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 16517330 — Surrogate Endpoint (SUR): Blood pressure
Study 29971397 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 24573909 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 25183657 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 12414853 — Surrogate Endpoint (SUR): Bone mineral density
Study 28161303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14557456 — Surrogate Endpoint (SUR): Blood pressure
Study 14557456 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23828194 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 23828194 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 20934602 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 19017831 — Surrogate Endpoint (SUR): Blood pressure
Study 16539632 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8549030 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 31452928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31452928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28270164 — Predictive Biomarker (PRD): CYLD mRNA
Genes: CYLD; CYLD1; KIAA0849; HSPC057
Study 28270164 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 21649843 — Surrogate Endpoint (SUR): Blood pressure
Study 10634368 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25909612 — Surrogate Endpoint (SUR): Blood pressure
Study 22276745 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28183443 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24039715 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 9493076 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 2474103 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2474103 — Surrogate Endpoint (SUR): Blood pressure
Study 30058460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26333778 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11313245 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 3373659 — Surrogate Endpoint (SUR): Blood pressure
Study 19108789 — Surrogate Endpoint (SUR): Blood pressure
Study 6705280 — Safety Biomarker (SAF): 51Cr-EDTA
Study 23515142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26823208 — Surrogate Endpoint (SUR): Blood pressure
Study 18476433 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 10228115 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30307902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30307902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30307902 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20649426 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7494615 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21706943 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16421476 — Surrogate Endpoint (SUR): Serum creatinine
Study 16421476 — Surrogate Endpoint (SUR): Blood pressure
Study 16421476 — Surrogate Endpoint (SUR): Serum potassium
Study 16002558 — Surrogate Endpoint (SUR): Blood pressure
Study 15673691 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15673691 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15673691 — Surrogate Endpoint (SUR): Serum calcium
Study 10573697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23635809 — Surrogate Endpoint (SUR): Blood pressure
Study 23635809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12891252 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12891252 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10367605 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10367605 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9638315 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 31154571 — Safety Biomarker (SAF): BDNF
Study 25968598 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19085178 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 11069570 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24073873 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 19965647 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 19965647 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 19965647 — Predictive Biomarker (PRD): MN1 mRNA
Genes: MN1
Study 8880369 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 23230962 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 21848963 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 9794174 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 654409 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23286418 — Surrogate Endpoint (SUR): Blood pressure
Study 16682681 — Surrogate Endpoint (SUR): Blood pressure
Study 11210397 — Surrogate Endpoint (SUR): Blood pressure
Study 3037863 — Surrogate Endpoint (SUR): Serum calcium
Study 31262189 — Surrogate Endpoint (SUR): Blood pressure
Study 28488912 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25944283 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 25944283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25944283 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 21525688 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18029218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18029218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16439507 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study 16439507 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16439507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12643400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12643400 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 12643400 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2567667 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28279499 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21664298 — Surrogate Endpoint (SUR): Blood pressure
Study 10837944 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9024957 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 30136633 — Surrogate Endpoint (SUR): Bone mineral density
Study 29736609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25162447 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 8659783 — Surrogate Endpoint (SUR): Blood pressure
Study 2150907 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21900585 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 16457894 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 10634454 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8957200 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8957200 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 1382156 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27546011 — Surrogate Endpoint (SUR): Pathological complete response
Study 24753507 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24753507 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12701935 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 10214535 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 220656 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27562137 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27562137 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26591359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15132728 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 2777438 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31178152 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20629665 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17039234 — Predictive Biomarker (PRD): TCF3 mRNA
Genes: TCF3; BHLHB21; E2A; ITF1
Study 17039234 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 17039234 — Predictive Biomarker (PRD): AFF1 mRNA
Genes: AFF1; AF4; FEL; MLLT2; PBM1
Study 8836273 — Surrogate Endpoint (SUR): Blood pressure
Study 30140899 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 26808146 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 24699551 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 11913886 — Surrogate Endpoint (SUR): Blood pressure
Study 9466539 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22424623 — Predictive Biomarker (PRD): SLC30A8 mRNA
Genes: SLC30A8; ZNT8
Study 17991660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17991660 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17991660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31308630 — Surrogate Endpoint (SUR): Serum creatinine
Study 29131002 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18647810 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 10535609 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10535609 — Safety Biomarker (SAF): IL16
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 31609296 — Surrogate Endpoint (SUR): Blood pressure
Study 30707881 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30707881 — Surrogate Endpoint (SUR): Blood pressure
Study 27083930 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30275526 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 30275526 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 30275526 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 30275526 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30275526 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 30275526 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 18024309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15655011 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 28695641 — Predictive Biomarker (PRD): MAPK8IP1 mRNA
Genes: MAPK8IP1; IB1; JIP1; PRKM8IP
Study 14760324 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 14760324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14760324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12213991 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9644739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9644739 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12917854 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 31254051 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11514041 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16889053 — Surrogate Endpoint (SUR): Blood pressure
Study 26997378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19643947 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 19643947 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9255202 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3912619 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28687908 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 28687908 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 24098072 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9171066 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7954259 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27529533 — Surrogate Endpoint (SUR): Serum uric acid
Study 21703613 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 31339011 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31303277 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 29258520 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24142686 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22515416 — Surrogate Endpoint (SUR): Blood pressure
Study 17459221 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 7547226 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 7547226 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26718418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26718418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25148458 — Predictive Biomarker (PRD): CTSZ mRNA
Genes: CTSZ
Study 25148458 — Predictive Biomarker (PRD): PRELID3B mRNA
Genes: PRELID3B; C20orf45; SLMO2; CGI-107
Study 25148458 — Predictive Biomarker (PRD): ATP5F1E mRNA
Genes: ATP5F1E; ATP5E
Study 25148458 — Predictive Biomarker (PRD): TRAM2 mRNA
Genes: TRAM2; KIAA0057
Study 25148458 — Predictive Biomarker (PRD): TMEM14A mRNA
Genes: TMEM14A; C6orf73; PTD011
Study 25148458 — Predictive Biomarker (PRD): MAP4K4 mRNA
Genes: MAP4K4; HGK; KIAA0687; NIK
Study 25148458 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19033818 — Surrogate Endpoint (SUR): Blood pressure
Study 1336526 — Surrogate Endpoint (SUR): Blood pressure
Study 30115553 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30115553 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 6678385 — Surrogate Endpoint (SUR): Blood pressure
Study 26875922 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26875922 — Surrogate Endpoint (SUR): Blood pressure
Study 12592686 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8564726 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8564726 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8564726 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 28392271 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28392271 — Safety Biomarker (SAF): BDNF
Study 25495666 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 20885182 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17074328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17074328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27723281 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 21688163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19357642 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19357642 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19357642 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2964980 — Safety Biomarker (SAF): 51Cr-EDTA
Study 2964980 — Surrogate Endpoint (SUR): Blood pressure
Study 27733252 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25568533 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25568533 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16499954 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16499954 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23003668 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 11778075 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9191824 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22149003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22149003 — Surrogate Endpoint (SUR): Blood pressure
Study 22149003 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10576122 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 10576122 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10576122 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3083467 — Surrogate Endpoint (SUR): Blood pressure
Study 16809802 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 14570793 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 14570793 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1360277 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26616678 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 26616678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26616678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17512550 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 15459914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15459914 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8535682 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA