TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20042310 — Surrogate Endpoint (SUR): Pathological complete response
Study 7579056 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31828962 — Surrogate Endpoint (SUR): Bone mineral density
Study 23249342 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 12166510 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12166510 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12166510 — Surrogate Endpoint (SUR): Serum creatinine
Study 31828291 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17976882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17976882 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17976882 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17122220 — Surrogate Endpoint (SUR): Blood pressure
Study 30522512 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27397927 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 27397927 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27397927 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27397927 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2455170 — Surrogate Endpoint (SUR): Blood pressure
Study 9154882 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 21690572 — Predictive Biomarker (PRD): Tubulin beta-3 chain
Genes: TUBB3; TUBB4
Study 11090595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11090595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11090595 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 11090595 — Safety Biomarker (SAF): Interleukin 1
Study 26078250 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 26078250 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 29023613 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21857315 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21857315 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2353184 — Surrogate Endpoint (SUR): Serum creatinine
Study 25794307 — Predictive Biomarker (PRD): DDN mRNA
Genes: DDN; KIAA0749
Study 27139255 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 22129516 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22129516 — Surrogate Endpoint (SUR): Blood pressure
Study 17672173 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 15601894 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 12521277 — Surrogate Endpoint (SUR): Serum calcium
Study 27020850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29331538 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 29331538 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 26259838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6149824 — Surrogate Endpoint (SUR): Blood pressure
Study 29530353 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 20721903 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17029631 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17029631 — Surrogate Endpoint (SUR): Blood pressure
Study 9038037 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9038037 — Surrogate Endpoint (SUR): Blood pressure
Study 15735115 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12877895 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12877895 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12877895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12877895 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1919803 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 30638739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30680401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22136963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18765182 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 15692600 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 15692600 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 7722713 — Surrogate Endpoint (SUR): Bone mineral density
Study 30650290 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 30650290 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 20008943 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 10818263 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 10818263 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 6441721 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 17912636 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12572098 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 2527993 — Surrogate Endpoint (SUR): Blood pressure
Study 25666468 — Surrogate Endpoint (SUR): Blood pressure
Study 21358389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1377307 — Surrogate Endpoint (SUR): Blood pressure
Study 3742933 — Surrogate Endpoint (SUR): Blood pressure
Study 24127467 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 18503113 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 18503113 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24859962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21030718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21030718 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21030718 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10194427 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10194427 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 8669327 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29857497 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 26417901 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 22337315 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15356671 — Surrogate Endpoint (SUR): Blood pressure
Study 2180549 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 25545543 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 23433769 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23433769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17683960 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31807750 — Surrogate Endpoint (SUR): Blood pressure
Study 16706244 — Safety Biomarker (SAF): Reactive oxygen species
Study 26004888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26004888 — Monitoring Biomarker (MOI): Procalcitonin
Study 22817768 — Predictive Biomarker (PRD): GABRG1 mRNA
Genes: GABRG1
Study 22817768 — Predictive Biomarker (PRD): GABRA2 mRNA
Genes: GABRA2
Study 19105405 — Surrogate Endpoint (SUR): Blood pressure
Study 15461995 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 15461995 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 2886821 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 21529740 — Surrogate Endpoint (SUR): Serum creatinine
Study 21529740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6366100 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30072263 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25219290 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 25219290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25219290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20211180 — Safety Biomarker (SAF): Hyaluronic acid
Study 16149365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7741341 — Surrogate Endpoint (SUR): Blood pressure
Study 2037704 — Surrogate Endpoint (SUR): Blood pressure
Study 28701501 — Surrogate Endpoint (SUR): Blood pressure
Study 24420550 — Surrogate Endpoint (SUR): Blood pressure
Study 21182510 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15964328 — Surrogate Endpoint (SUR): Blood pressure
Study 10076915 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10076915 — Surrogate Endpoint (SUR): Blood pressure
Study 9374948 — Surrogate Endpoint (SUR): Blood pressure
Study 31672939 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 31672939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30645842 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 30645842 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 25047312 — Surrogate Endpoint (SUR): Blood pressure
Study 18226581 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15976214 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 16047027 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 2209300 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2209300 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31305297 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25934853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21325445 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24861492 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 20200382 — Surrogate Endpoint (SUR): Blood pressure
Study 18056580 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 30888751 — Monitoring Biomarker (MOI): HBV DNA
Study 12575605 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14633817 — Surrogate Endpoint (SUR): Blood pressure
Study 22030947 — Surrogate Endpoint (SUR): Blood pressure
Study 18465339 — Predictive Biomarker (PRD): Hormone receptor
Study 23111127 — Surrogate Endpoint (SUR): Blood pressure
Study 21740829 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21740829 — Surrogate Endpoint (SUR): Blood pressure
Study 11157369 — Surrogate Endpoint (SUR): Blood pressure
Study 8492688 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21362764 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 8081430 — Surrogate Endpoint (SUR): Blood pressure
Study 29514693 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 25651922 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23508603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21439529 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21439529 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17138156 — Surrogate Endpoint (SUR): Blood pressure
Study 10781117 — Surrogate Endpoint (SUR): Blood pressure
Study 1731596 — Predictive Biomarker (PRD): HMX1 mRNA
Genes: HMX1; H6
Study 6150888 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 11352951 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27662442 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 21396848 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31983056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31983056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24604234 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 16637392 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 16637392 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 14695409 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10631409 — Surrogate Endpoint (SUR): Serum creatinine
Study 25148570 — Predictive Biomarker (PRD): MARCHF2 mRNA
Genes: MARCHF2; MARCH2; RNF172; HSPC240
Study 23271771 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9407413 — Safety Biomarker (SAF): Protein AMBP
Genes: AMBP; HCP; ITIL
Study 9407413 — Surrogate Endpoint (SUR): Blood pressure
Study 9407413 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25978746 — Surrogate Endpoint (SUR): Blood pressure
Study 21242555 — Surrogate Endpoint (SUR): Blood pressure
Study 10770814 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27902984 — Predictive Biomarker (PRD): SCGB1A1 mRNA
Genes: SCGB1A1; CC10; CCSP; UGB
Study 12679946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28245873 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28245873 — Safety Biomarker (SAF): Reactive oxygen species
Study 17925021 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17925021 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17925021 — Surrogate Endpoint (SUR): Blood pressure
Study 9728836 — Predictive Biomarker (PRD): SERPINI2 mRNA
Genes: SERPINI2; MEPI; PI14
Study 110504 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 11816629 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8148355 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3207070 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24559010 — Surrogate Endpoint (SUR): Blood pressure
Study 17594937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17594937 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20597268 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16627141 — Surrogate Endpoint (SUR): Bone mineral density
Study 14645424 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30666747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30666747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19463377 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 14984519 — Surrogate Endpoint (SUR): Blood pressure
Study 29229354 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 29229354 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29229354 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 27616162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27616162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27616162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27616162 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 468444 — Surrogate Endpoint (SUR): Blood pressure
Study 9527088 — Surrogate Endpoint (SUR): Blood pressure
Study 7610803 — Predictive Biomarker (PRD): GRHL3 mRNA
Genes: GRHL3; SOM; TFCP2L4
Study 28093483 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16960779 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14722635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14722635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21047567 — Surrogate Endpoint (SUR): Bone mineral density
Study 30335610 — Surrogate Endpoint (SUR): Blood pressure
Study 24979615 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24979615 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8969572 — Surrogate Endpoint (SUR): Blood pressure
Study 19880855 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 31144240 — Predictive Biomarker (PRD): GCLC mRNA
Genes: GCLC; GLCL; GLCLC
Study 31144240 — Safety Biomarker (SAF): Reactive oxygen species
Study 23646467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23646467 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23646467 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 21212932 — Surrogate Endpoint (SUR): Serum potassium
Study 19302913 — Surrogate Endpoint (SUR): Blood pressure
Study 28711472 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 11823757 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10383006 — Surrogate Endpoint (SUR): Blood pressure
Study 1757907 — Surrogate Endpoint (SUR): Serum creatinine
Study 24337078 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18551086 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 10199763 — Surrogate Endpoint (SUR): Bone mineral density
Study 10199763 — Surrogate Endpoint (SUR): Serum calcium
Study 2121060 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 25854875 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 25854875 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 25854875 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 25854875 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 24504810 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29728074 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 16184030 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28637418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28637418 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 28637418 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28637418 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28637418 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28637418 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16946127 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15464489 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17980970 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10445622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10445622 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2310660 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6196556 — Surrogate Endpoint (SUR): Blood pressure
Study 22709754 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 7608311 — Surrogate Endpoint (SUR): Blood pressure
Study 31529024 — Surrogate Endpoint (SUR): Blood pressure
Study 19474264 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 30817739 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 29685828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26309227 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 25709122 — Surrogate Endpoint (SUR): Serum creatinine
Study 25709122 — Surrogate Endpoint (SUR): Blood pressure
Study 18766426 — Safety Biomarker (SAF): Interleukin 1
Study 15172898 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 15172898 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8996762 — Monitoring Biomarker (MOI): HBV DNA
Study 25420455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22352120 — Surrogate Endpoint (SUR): Blood pressure
Study 16761467 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1316400 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30020512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30020512 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26628419 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24658390 — Surrogate Endpoint (SUR): Blood pressure
Study 11981066 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319