TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19558539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19558539 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19558539 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15456517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22856338 — Surrogate Endpoint (SUR): Blood pressure
Study 15794740 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31612193 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 8231842 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29737068 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 24996524 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH
Study 21718999 — Safety Biomarker (SAF): Hyaluronic acid
Study 19121772 — Surrogate Endpoint (SUR): Blood pressure
Study 14668568 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9833167 — Surrogate Endpoint (SUR): Blood pressure
Study 8058004 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31403327 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 19930236 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 18160753 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15485474 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30318393 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 30318393 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28280053 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24853591 — Safety Biomarker (SAF): Hyaluronic acid
Study 3310750 — Surrogate Endpoint (SUR): Blood pressure
Study 16899602 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 16899602 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28369940 — Predictive Biomarker (PRD): IRS2 mRNA
Genes: IRS2
Study 28369940 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 28369940 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 26178500 — Surrogate Endpoint (SUR): Blood pressure
Study 28982804 — Surrogate Endpoint (SUR): Blood pressure
Study 23838604 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23838604 — Predictive Biomarker (PRD): PRKCQ mRNA
Genes: PRKCQ; PRKCT
Study 23838604 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 23838604 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 21947196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21947196 — Safety Biomarker (SAF): Interleukin 1
Study 21947196 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 16926660 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3893805 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26450000 — Surrogate Endpoint (SUR): Blood pressure
Study 8555377 — Predictive Biomarker (PRD): SLC6A7 mRNA
Genes: SLC6A7; PROT
Study 21115010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21115010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24144760 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24144760 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24144760 — Surrogate Endpoint (SUR): Serum creatinine
Study 21563879 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11087152 — Surrogate Endpoint (SUR): Blood pressure
Study 30686305 — Surrogate Endpoint (SUR): Blood pressure
Study 28552382 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19696778 — Surrogate Endpoint (SUR): Blood pressure
Study 19696778 — Surrogate Endpoint (SUR): Serum uric acid
Study 19696778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19696778 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9817192 — Surrogate Endpoint (SUR): Blood pressure
Study 25406305 — Surrogate Endpoint (SUR): Blood pressure
Study 23913386 — Surrogate Endpoint (SUR): Blood pressure
Study 21306709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21306709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21306709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11421501 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 8305994 — Surrogate Endpoint (SUR): Blood pressure
Study 8305994 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8305994 — Safety Biomarker (SAF): Urinary microalbumin
Study 3828550 — Surrogate Endpoint (SUR): Blood pressure
Study 3828550 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11454883 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9743505 — Surrogate Endpoint (SUR): Blood pressure
Study 7920316 — Surrogate Endpoint (SUR): Blood pressure
Study 31650412 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 22592094 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14697462 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2656603 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25910537 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21717993 — Surrogate Endpoint (SUR): Blood pressure
Study 17701771 — Surrogate Endpoint (SUR): Bone mineral density
Study 15521894 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23196938 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23196938 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23196938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8222176 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8222176 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20447070 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 20447070 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8913316 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8913316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24316553 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24316553 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17634538 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 17634538 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 12479631 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 224478 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 224478 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 26316598 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23159435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23159435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23159435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23159435 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 23159435 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16394035 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 7640648 — Surrogate Endpoint (SUR): Blood pressure
Study 105443 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28153102 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26077375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26077375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15447818 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30220702 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28459932 — Surrogate Endpoint (SUR): Blood pressure
Study 15593037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15593037 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31484191 — Surrogate Endpoint (SUR): Blood pressure
Study 28418082 — Predictive Biomarker (PRD): TRAF3 mRNA
Genes: TRAF3; CAP-1; CRAF1; TRAFAMN
Study 28418082 — Predictive Biomarker (PRD): MAP3K14 mRNA
Genes: MAP3K14; NIK
Study 28418082 — Safety Biomarker (SAF): miR-133b
Genes: MIR133B
Study 26266387 — Surrogate Endpoint (SUR): Blood pressure
Study 18926865 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17713973 — Predictive Biomarker (PRD): CCR1 mRNA
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 17713973 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 15389187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9783305 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2969740 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2969740 — Surrogate Endpoint (SUR): Blood pressure
Study 30833375 — Surrogate Endpoint (SUR): Blood pressure
Study 28833481 — Surrogate Endpoint (SUR): Blood pressure
Study 23966058 — Surrogate Endpoint (SUR): Blood pressure
Study 20506126 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 30867017 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24564568 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 20010073 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22717305 — Surrogate Endpoint (SUR): Serum creatinine
Study 22717305 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 20027097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11991670 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 30524137 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30524137 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18038273 — Surrogate Endpoint (SUR): Bone mineral density
Study 16152821 — Surrogate Endpoint (SUR): Blood pressure
Study 12505568 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2050329 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30658483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30658483 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30658483 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 30658483 — Safety Biomarker (SAF): Hyaluronic acid
Study 25733459 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23091134 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19650424 — Safety Biomarker (SAF): Reactive oxygen species
Study 15379756 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30176835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15920042 — Surrogate Endpoint (SUR): Blood pressure
Study 3203706 — Surrogate Endpoint (SUR): Blood pressure
Study 2407810 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2407810 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31479152 — Surrogate Endpoint (SUR): Bone mineral density
Study 25826125 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 25826125 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 25826125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17597461 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 25255724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22117989 — Surrogate Endpoint (SUR): Blood pressure
Study 22117989 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16606971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16606971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2408250 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22813209 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 20367987 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16255877 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30830545 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 19342470 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17917503 — Surrogate Endpoint (SUR): Blood pressure
Study 7056273 — Surrogate Endpoint (SUR): Blood pressure
Study 20180429 — Surrogate Endpoint (SUR): Serum testosterone
Study 17587789 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17587789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24107738 — Surrogate Endpoint (SUR): Blood pressure
Study 11328423 — Surrogate Endpoint (SUR): Sperm parameters
Study 2463564 — Surrogate Endpoint (SUR): Blood pressure
Study 23052417 — Surrogate Endpoint (SUR): Blood pressure
Study 17964516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17964516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16234004 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12196491 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7778530 — Surrogate Endpoint (SUR): Blood pressure
Study 30082554 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23581458 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23581458 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19804822 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 19804822 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 12783400 — Surrogate Endpoint (SUR): Serum creatinine
Study 10981544 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 10981544 — Surrogate Endpoint (SUR): Blood pressure
Study 10981544 — Surrogate Endpoint (SUR): Serum potassium
Study 24909860 — Surrogate Endpoint (SUR): Blood pressure
Study 22015818 — Surrogate Endpoint (SUR): Bone mineral density
Study 8712867 — Surrogate Endpoint (SUR): Bone mineral density
Study 16177289 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12783702 — Surrogate Endpoint (SUR): Blood pressure
Study 9063959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9063959 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24325584 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24325584 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29461392 — Surrogate Endpoint (SUR): Blood pressure
Study 12209673 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 12209673 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 7856897 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25545380 — Surrogate Endpoint (SUR): Bone mineral density
Study 23289819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23289819 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15534490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11251475 — Surrogate Endpoint (SUR): Blood pressure
Study 9250117 — Surrogate Endpoint (SUR): Blood pressure
Study 9250117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17165349 — Surrogate Endpoint (SUR): Blood pressure
Study 10440146 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 2352762 — Surrogate Endpoint (SUR): Blood pressure
Study 18347776 — Surrogate Endpoint (SUR): Blood pressure
Study 15950139 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20527063 — Safety Biomarker (SAF): Interleukin 1
Study 20527063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20527063 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18585701 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7586616 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7586616 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 6418074 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18925521 — Safety Biomarker (SAF): Reactive oxygen species
Study 31336393 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31336393 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31336393 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11568992 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8179790 — Surrogate Endpoint (SUR): Blood pressure
Study 3067809 — Surrogate Endpoint (SUR): Blood pressure
Study 27316632 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 10913928 — Surrogate Endpoint (SUR): Bone mineral density
Study 26329381 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 24629063 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 16140677 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30711698 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23899172 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23899172 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21742102 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21742102 — Surrogate Endpoint (SUR): Blood pressure
Study 3041936 — Surrogate Endpoint (SUR): Blood pressure
Study 30760406 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28697773 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28697773 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16817738 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29490986 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 29490986 — Predictive Biomarker (PRD): FAT1 mRNA
Genes: FAT1; CDHF7; FAT
Study 29490986 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 29490986 — Predictive Biomarker (PRD): KMT2D mRNA
Genes: KMT2D; ALR; MLL2; MLL4
Study 29490986 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 29490986 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 29490986 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 29490986 — Predictive Biomarker (PRD): NOTCH2 mRNA
Genes: NOTCH2
Study 29490986 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 29490986 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 10204818 — Surrogate Endpoint (SUR): Blood pressure
Study 7481551 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6446424 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 12042267 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29247643 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study 29247643 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 29247643 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 29247643 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 21282192 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17109579 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9312206 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 2511277 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2511277 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 15983798 — Surrogate Endpoint (SUR): Blood pressure
Study 23182608 — Surrogate Endpoint (SUR): Blood pressure
Study 19201627 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 16639483 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 16639483 — Surrogate Endpoint (SUR): Bone mineral density
Study 26376111 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26376111 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 21208766 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 18670379 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15749485 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 12605581 — Surrogate Endpoint (SUR): Blood pressure
Study 6666218 — Surrogate Endpoint (SUR): Blood pressure