TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12679447 — Surrogate Endpoint (SUR): Blood pressure
Study 10616235 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2033429 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27744007 — Surrogate Endpoint (SUR): Blood pressure
Study 23639243 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20884893 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16338010 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10851665 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10851665 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 1917227 — Surrogate Endpoint (SUR): Blood pressure
Study 29471132 — Safety Biomarker (SAF): Interleukin 1
Study 29471132 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12461831 — Surrogate Endpoint (SUR): Blood pressure
Study 10624752 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 2109470 — Surrogate Endpoint (SUR): Blood pressure
Study 29432640 — Surrogate Endpoint (SUR): Bacterial count
Study 25467093 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25467093 — Surrogate Endpoint (SUR): Blood pressure
Study 25765696 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27914492 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25618415 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 25618415 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 21943132 — Surrogate Endpoint (SUR): Blood pressure
Study 18301974 — Surrogate Endpoint (SUR): Bone mineral density
Study 29079990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29103871 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31888745 — Surrogate Endpoint (SUR): Blood pressure
Study 24975199 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 28102098 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 28102098 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 23545926 — Safety Biomarker (SAF): Hyaluronic acid
Study 18373141 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 18373141 — Surrogate Endpoint (SUR): Blood pressure
Study 1530677 — Surrogate Endpoint (SUR): Blood pressure
Study 3968001 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30796036 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30796036 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 30796036 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30796036 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30796036 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 30796036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 15031340 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9839657 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 9839657 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27322814 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17033231 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 17033231 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 12689404 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 1412183 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1412183 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25080537 — Surrogate Endpoint (SUR): Blood pressure
Study 23463680 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 2949169 — Surrogate Endpoint (SUR): Blood pressure
Study 22983778 — Surrogate Endpoint (SUR): Blood pressure
Study 18042473 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31775403 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 31775403 — Surrogate Endpoint (SUR): Bone mineral density
Study 15353978 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21069379 — Surrogate Endpoint (SUR): Blood pressure
Study 19477353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27930383 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24057202 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 19794330 — Predictive Biomarker (PRD): HTR3A mRNA
Genes: HTR3A; 5HT3R; HTR3
Study 7924177 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7924177 — Surrogate Endpoint (SUR): Serum sodium
Study 7924177 — Surrogate Endpoint (SUR): Serum potassium
Study 7924177 — Surrogate Endpoint (SUR): Serum creatinine
Study 7924177 — Surrogate Endpoint (SUR): Blood pressure
Study 22538532 — Surrogate Endpoint (SUR): Blood pressure
Study 11049908 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11049908 — Surrogate Endpoint (SUR): Blood pressure
Study 30091061 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30091061 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30091061 — Surrogate Endpoint (SUR): Serum creatinine
Study 8595510 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2651031 — Surrogate Endpoint (SUR): Blood pressure
Study 28847751 — Predictive Biomarker (PRD): SMAD7 mRNA
Genes: SMAD7; MADH7; MADH8
Study 27306435 — Surrogate Endpoint (SUR): Blood pressure
Study 27306435 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27306435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24769270 — Surrogate Endpoint (SUR): Blood pressure
Study 18404609 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18404609 — Surrogate Endpoint (SUR): Blood pressure
Study 16162741 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 9259823 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10090111 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31663620 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 25591799 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25591799 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25618969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25618969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25618969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25618969 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25618969 — Safety Biomarker (SAF): Reactive oxygen species
Study 25618969 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25618969 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20888887 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 20888887 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 2097908 — Surrogate Endpoint (SUR): Blood pressure
Study 16356228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16356228 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12421159 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 12421159 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 29358012 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15897788 — Surrogate Endpoint (SUR): Blood pressure
Study 15897788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15897788 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19857446 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19857446 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15579914 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15579914 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 31067329 — Surrogate Endpoint (SUR): Bone mineral density
Study 21946824 — Safety Biomarker (SAF): Reactive oxygen species
Study 12032174 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 12032174 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10090350 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 26673130 — Surrogate Endpoint (SUR): Blood pressure
Study 23019945 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23019945 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23019945 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7769306 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2284577 — Surrogate Endpoint (SUR): Serum creatinine
Study 28522317 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28522317 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 23601741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17307303 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 17307303 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 30595567 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 8829162 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 8101024 — Surrogate Endpoint (SUR): Blood pressure
Study 2946838 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2946838 — Surrogate Endpoint (SUR): Serum sodium
Study 24013058 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17472022 — Surrogate Endpoint (SUR): Blood pressure
Study 12829659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12829659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29415163 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 29952453 — Safety Biomarker (SAF): Hyaluronic acid
Study 21934474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21934474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30241119 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 15567456 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 15567456 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12080647 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26955673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17978109 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11970761 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10323055 — Surrogate Endpoint (SUR): Blood pressure
Study 26051236 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20663999 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19858398 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 19858398 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 19858398 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 19858398 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 19858398 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 19858398 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 19858398 — Safety Biomarker (SAF): MTHFR
Study 16431254 — Surrogate Endpoint (SUR): Serum testosterone
Study 16431254 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 16431254 — Surrogate Endpoint (SUR): Bone mineral density
Study 22949154 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 20738171 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 25504030 — Predictive Biomarker (PRD): PCSK7 mRNA
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 22142350 — Surrogate Endpoint (SUR): Blood pressure
Study 19410462 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2236444 — Surrogate Endpoint (SUR): Blood pressure
Study 31366975 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31366975 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31366975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31366975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31366975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28264739 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22129109 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11509263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11509263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11509263 — Safety Biomarker (SAF): Reactive oxygen species
Study 19781431 — Surrogate Endpoint (SUR): Blood pressure
Study 12969156 — Surrogate Endpoint (SUR): Blood pressure
Study 9377617 — Surrogate Endpoint (SUR): Blood pressure
Study 3965001 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 18602250 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 19590194 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16520399 — Surrogate Endpoint (SUR): Blood pressure
Study 10689265 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 11071974 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11071974 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11071974 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9068933 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 3785647 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 26463420 — Surrogate Endpoint (SUR): Blood pressure
Study 23158856 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20627914 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10829989 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20446083 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15751604 — Predictive Biomarker (PRD): AIRE mRNA
Genes: AIRE; APECED
Study 15751604 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 15751604 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15751604 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15751604 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 12081605 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12081605 — Monitoring Biomarker (MOI): HBV DNA
Study 2024560 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2024560 — Surrogate Endpoint (SUR): Blood pressure
Study 26435060 — Predictive Biomarker (PRD): ENHO mRNA
Genes: ENHO; C9orf165; UNQ470/PRO830
Study 10658681 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10658681 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29117472 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25220877 — Surrogate Endpoint (SUR): Blood pressure
Study 18561878 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 25630874 — Surrogate Endpoint (SUR): Bone mineral density
Study 21857489 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21857489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21857489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18254574 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7795829 — Surrogate Endpoint (SUR): Blood pressure
Study 2393206 — Surrogate Endpoint (SUR): Serum creatinine
Study 25788197 — Monitoring Biomarker (MOI): HBV DNA
Study 21414565 — Surrogate Endpoint (SUR): Blood pressure
Study 19153265 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 10968732 — Surrogate Endpoint (SUR): Blood pressure
Study 26757788 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 26757788 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 26757788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24119318 — Surrogate Endpoint (SUR): Blood pressure
Study 20182454 — Surrogate Endpoint (SUR): Blood pressure
Study 7910836 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25873635 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19450647 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 14556922 — Predictive Biomarker (PRD): Hormone receptor
Study 18713550 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18713550 — Surrogate Endpoint (SUR): Blood pressure
Study 16410271 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 9159565 — Surrogate Endpoint (SUR): Blood pressure
Study 9695971 — Predictive Biomarker (PRD): THPO mRNA
Genes: THPO; MGDF
Study 9695971 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 2530922 — Surrogate Endpoint (SUR): Blood pressure
Study 31629371 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30582281 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27906549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27906549 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 27906549 — Safety Biomarker (SAF): Reactive oxygen species
Study 19776082 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 16060411 — Surrogate Endpoint (SUR): Blood pressure
Study 24940305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24940305 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24940305 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 24940305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21492178 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11557915 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 11557915 — Surrogate Endpoint (SUR): Blood pressure
Study 20181971 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11078178 — Surrogate Endpoint (SUR): Blood pressure
Study 11078178 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15116824 — Surrogate Endpoint (SUR): Bone mineral density
Study 10779091 — Surrogate Endpoint (SUR): Blood pressure
Study 10779091 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30286820 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30286820 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20022262 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 15851916 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study 12416946 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 29948276 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 29948276 — Predictive Biomarker (PRD): TKT mRNA
Genes: TKT
Study 19300303 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 16776576 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21936938 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14720267 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9485131 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9485131 — Surrogate Endpoint (SUR): Blood pressure
Study 23743976 — Surrogate Endpoint (SUR): Blood pressure
Study 19057983 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 14681639 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14681639 — Predictive Biomarker (PRD): FGF7 mRNA
Genes: FGF7; KGF
Study 14681639 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 14681639 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14681639 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12218523 — Surrogate Endpoint (SUR): Serum creatinine
Study 2789920 — Surrogate Endpoint (SUR): Serum calcium
Study 31785624 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 31785624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 31785624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 31785624 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 31785624 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23793945 — Surrogate Endpoint (SUR): Blood pressure
Study 23793945 — Surrogate Endpoint (SUR): Serum creatinine
Study 16186399 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11511425 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29135656 — Surrogate Endpoint (SUR): Blood pressure
Study 30824647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26124478 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 2454372 — Surrogate Endpoint (SUR): Blood pressure
Study 29032853 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 3099102 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29511780 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24724577 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 19604542 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP