TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31594394 — Surrogate Endpoint (SUR): Blood pressure
Study 29053185 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 17692951 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16815780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11594525 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11594525 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8466377 — Surrogate Endpoint (SUR): Blood pressure
Study 24980650 — Surrogate Endpoint (SUR): Blood pressure
Study 31678307 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 21562068 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21562068 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15508793 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 11557163 — Safety Biomarker (SAF): DRD2
Study 11557163 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 26269563 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 26269563 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 26269563 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 26269563 — Predictive Biomarker (PRD): EN1 mRNA
Genes: EN1
Study 26269563 — Predictive Biomarker (PRD): EMX1 mRNA
Genes: EMX1
Study 26269563 — Predictive Biomarker (PRD): PCDH10 mRNA
Genes: PCDH10; KIAA1400
Study 26269563 — Predictive Biomarker (PRD); Safety Biomarker (SAF): RPRM mRNA
Genes: RPRM
Study 26269563 — Predictive Biomarker (PRD): RSPO2 mRNA
Genes: RSPO2; UNQ9384/PRO34209
Study 26269563 — Predictive Biomarker (PRD): SORCS3 mRNA
Genes: SORCS3; KIAA1059
Study 26269563 — Predictive Biomarker (PRD): ZIC1 mRNA
Genes: ZIC1; ZIC; ZNF201
Study 26269563 — Predictive Biomarker (PRD): ZNF610 mRNA
Genes: ZNF610
Study 21511222 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 2459525 — Surrogate Endpoint (SUR): Blood pressure
Study 11320947 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 19854632 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16118573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16118573 — Safety Biomarker (SAF): IL-6 and IL-10
Study 27080343 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 27080343 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 27080343 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 27080343 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27080343 — Safety Biomarker (SAF): Interleukin 1
Study 27080343 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27080343 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24622750 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 19029269 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10357338 — Surrogate Endpoint (SUR): Blood pressure
Study 8546442 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 1672870 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1672870 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31247504 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 24251120 — Predictive Biomarker (PRD): NANOS1 mRNA
Genes: NANOS1; NOS1
Study 17708607 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 15087291 — Surrogate Endpoint (SUR): Blood pressure
Study 2567740 — Surrogate Endpoint (SUR): Blood pressure
Study 182105 — Predictive Biomarker (PRD): TERF1 mRNA
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study 21904105 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 30167757 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22836071 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16154437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8895267 — Surrogate Endpoint (SUR): Blood pressure
Study 27621597 — Safety Biomarker (SAF): Th2 cell
Study 21051656 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7625665 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25271015 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23496897 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 7883133 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 18307280 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 18307280 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18307280 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 18307280 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 10716466 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10716466 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27653383 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 25639140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23686277 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 15681945 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10362454 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7723156 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7723156 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7362505 — Surrogate Endpoint (SUR): Blood pressure
Study 28779963 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18079221 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8942440 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27364372 — Safety Biomarker (SAF): Hyaluronic acid
Study 12769161 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12769161 — Surrogate Endpoint (SUR): Blood pressure
Study 30473019 — Predictive Biomarker (PRD): MPST mRNA
Genes: MPST; TST2
Study 15868442 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 8689817 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30968542 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 30968542 — Predictive Biomarker (PRD): CILP mRNA
Genes: CILP; UNQ602/PRO1188
Study 24402636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24402636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17095745 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9813583 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21840914 — Surrogate Endpoint (SUR): Blood pressure
Study 16680923 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9726718 — Surrogate Endpoint (SUR): Serum potassium
Study 27966565 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25370206 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 21640360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18963025 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 18963025 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 16880095 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 12964783 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30730346 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28126300 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23095307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21172842 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17652181 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11896478 — Surrogate Endpoint (SUR): Blood pressure
Study 28100551 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19064822 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 19499272 — Surrogate Endpoint (SUR): Bone mineral density
Study 7799337 — Safety Biomarker (SAF): Interleukin 1
Study 25146365 — Surrogate Endpoint (SUR): Blood pressure
Study 21592715 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 20664127 — Surrogate Endpoint (SUR): Blood pressure
Study 24283773 — Safety Biomarker (SAF): Interleukin 1
Study 19056900 — Surrogate Endpoint (SUR): Serum calcium
Study 16563974 — Surrogate Endpoint (SUR): Serum creatinine
Study 6751003 — Surrogate Endpoint (SUR): Blood pressure
Study 27460618 — Safety Biomarker (SAF): BDNF
Study 27460618 — Surrogate Endpoint (SUR): Blood pressure
Study 19685757 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8526620 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 2405964 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20535962 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6427714 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30998422 — Safety Biomarker (SAF): Reactive oxygen species
Study 12672711 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12672711 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12672711 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10744143 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10744143 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2413307 — Surrogate Endpoint (SUR): Blood pressure
Study 30452784 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30452784 — Surrogate Endpoint (SUR): Blood pressure
Study 27717303 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27717303 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 27717303 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27717303 — Predictive Biomarker (PRD): Hormone receptor
Study 1461544 — Surrogate Endpoint (SUR): Blood pressure
Study 26704011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18444869 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18444869 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 18444869 — Surrogate Endpoint (SUR): Bone mineral density
Study 9052302 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8379601 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 23525434 — Surrogate Endpoint (SUR): Blood pressure
Study 16622748 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 2969315 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2969315 — Surrogate Endpoint (SUR): Blood pressure
Study 31937274 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 26156941 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 17846310 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15535408 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9516068 — Surrogate Endpoint (SUR): Blood pressure
Study 7759428 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7759428 — Surrogate Endpoint (SUR): Blood pressure
Study 16546755 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 16546755 — Safety Biomarker (SAF): Reactive oxygen species
Study 10896637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10896637 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10896637 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26946333 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 21684022 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21684022 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 21684022 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 21684022 — Safety Biomarker (SAF): BDNF
Study 17388762 — Surrogate Endpoint (SUR): Blood pressure
Study 7564369 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7564369 — Surrogate Endpoint (SUR): Blood pressure
Study 29402509 — Surrogate Endpoint (SUR): Blood pressure
Study 8945675 — Surrogate Endpoint (SUR): Blood pressure
Study 28142075 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 28142075 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22595153 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 22595153 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22595153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15323595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23758279 — Surrogate Endpoint (SUR): Blood pressure
Study 18809153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10795662 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8641640 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29315212 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 29315212 — Surrogate Endpoint (SUR): Serum creatinine
Study 22805873 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 22805873 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 22805873 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9139554 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30042362 — Surrogate Endpoint (SUR): Blood pressure
Study 26760452 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24951991 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 20210614 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20210614 — Predictive Biomarker (PRD): PRSS27 mRNA
Genes: PRSS27; MPN; UNQ1884/PRO4327
Study 31277073 — Predictive Biomarker (PRD): BMPR1B mRNA
Genes: BMPR1B
Study 31277073 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study 31277073 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 31277073 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A2 mRNA
Genes: SRD5A2
Study 24341367 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 19615128 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8512099 — Surrogate Endpoint (SUR): Blood pressure
Study 22781525 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15753747 — Surrogate Endpoint (SUR): Serum sodium
Study 28816833 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 23500267 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15298946 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15298946 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11735185 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31233893 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 31233893 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study 19439813 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 19439813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31809216 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 25074639 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 16562643 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16562643 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20969664 — Safety Biomarker (SAF): Hyaluronic acid
Study 9041968 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29870868 — Surrogate Endpoint (SUR): Blood pressure
Study 20520603 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 16651305 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 12792354 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9952072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9952072 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24299019 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24299019 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21157172 — Surrogate Endpoint (SUR): Blood pressure
Study 16158081 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 23279372 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 21995804 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 18812677 — Surrogate Endpoint (SUR): Serum creatinine
Study 18812677 — Surrogate Endpoint (SUR): Blood pressure
Study 10988110 — Surrogate Endpoint (SUR): Bone mineral density
Study 26948284 — Surrogate Endpoint (SUR): Blood pressure
Study 24709636 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17889355 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17889355 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 14712432 — Surrogate Endpoint (SUR): Blood pressure
Study 11842483 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 28545589 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 21895947 — Surrogate Endpoint (SUR): Blood pressure
Study 1422320 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 1422320 — Surrogate Endpoint (SUR): Bone mineral density
Study 28961803 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study 18311576 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 14597524 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 14597524 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 1578626 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27644242 — Surrogate Endpoint (SUR): Serum uric acid
Study 25208075 — Surrogate Endpoint (SUR): Blood pressure
Study 20531106 — Surrogate Endpoint (SUR): Blood pressure
Study 20531106 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 20531106 — Surrogate Endpoint (SUR): Serum sodium
Study 24108780 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 7662225 — Surrogate Endpoint (SUR): Blood pressure
Study 2758384 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21755327 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19663689 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 19663689 — Safety Biomarker (SAF): Cytochrome c
Study 27584715 — Safety Biomarker (SAF): Hyaluronic acid
Study 20172127 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 18271430 — Surrogate Endpoint (SUR): Blood pressure
Study 30813125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28187506 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 28187506 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 28187506 — Predictive Biomarker (PRD): NR1I2 mRNA
Genes: NR1I2; PXR
Study 26125924 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19366826 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 19366826 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19366826 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19366826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 19366826 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 17190733 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17190733 — Surrogate Endpoint (SUR): Blood pressure
Study 31512815 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 24345793 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 18595436 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11863118 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 2076391 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 2076391 — Predictive Biomarker (PRD): TET1 mRNA
Genes: TET1; CXXC6; KIAA1676; LCX
Study 22143010 — Surrogate Endpoint (SUR): Blood pressure
Study 3534584 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26254196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26254196 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26254196 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19502018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11082213 — Surrogate Endpoint (SUR): Blood pressure
Study 9032569 — Surrogate Endpoint (SUR): Bone mineral density
Study 1456855 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1456855 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1456855 — Surrogate Endpoint (SUR): Blood pressure
Study 31171092 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31171092 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19046724 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19046724 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10570675 — Surrogate Endpoint (SUR): Blood pressure
Study 10570675 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10570675 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29097225 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 16052765 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 7734252 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 7734252 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22219027 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 14735048 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31492766 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31492766 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19660002 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 16537872 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26354560 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26354560 — Surrogate Endpoint (SUR): Blood pressure
Study 20184444 — Surrogate Endpoint (SUR): Blood pressure
Study 19032138 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1