TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18520294 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15893182 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31971678 — Surrogate Endpoint (SUR): Bone mineral density
Study 23681967 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 23681967 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23659666 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11271189 — Surrogate Endpoint (SUR): Serum creatinine
Study 28893900 — Surrogate Endpoint (SUR): Blood pressure
Study 16965728 — Surrogate Endpoint (SUR): Blood pressure
Study 16965728 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16876495 — Surrogate Endpoint (SUR): Bone mineral density
Study 8529760 — Surrogate Endpoint (SUR): Blood pressure
Study 1952145 — Surrogate Endpoint (SUR): Blood pressure
Study 27574886 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9068393 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9068393 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 4009330 — Surrogate Endpoint (SUR): Serum potassium
Study 26194532 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 8739023 — Surrogate Endpoint (SUR): Blood pressure
Study 29631362 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 10386179 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 22835668 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17643772 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9526937 — Surrogate Endpoint (SUR): Blood pressure
Study 7983291 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7983291 — Surrogate Endpoint (SUR): Blood pressure
Study 7983291 — Surrogate Endpoint (SUR): Serum creatinine
Study 7983291 — Surrogate Endpoint (SUR): Serum potassium
Study 29962180 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29962180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29962180 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29962180 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10527977 — Surrogate Endpoint (SUR): Serum calcium
Study 29961920 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27455318 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27455318 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10612536 — Surrogate Endpoint (SUR): Bacterial count
Study 24285801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16112972 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16112972 — Surrogate Endpoint (SUR): Blood pressure
Study 11770708 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9037443 — Surrogate Endpoint (SUR): Blood pressure
Study 2737688 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2737688 — Surrogate Endpoint (SUR): Blood pressure
Study 21087377 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7051762 — Surrogate Endpoint (SUR): Blood pressure
Study 22728693 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 19846026 — Monitoring Biomarker (MOI): HBV DNA
Study 17561998 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 15447895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15447895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2643284 — Surrogate Endpoint (SUR): Blood pressure
Study 9504133 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31786338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29450468 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29450468 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20305865 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7776678 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21613575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21613575 — Safety Biomarker (SAF): IL-6 and IL-10
Study 3318724 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3318724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24594059 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 12795770 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 12795770 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24848975 — Safety Biomarker (SAF): Hyaluronic acid
Study 19521894 — Surrogate Endpoint (SUR): Blood pressure
Study 15084937 — Surrogate Endpoint (SUR): Serum creatinine
Study 2442559 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24093858 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 24093858 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21346065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17263129 — Predictive Biomarker (PRD): Liver iron
Study 17263129 — Surrogate Endpoint (SUR): Serum creatinine
Study 12296610 — Surrogate Endpoint (SUR): Blood pressure
Study 25729878 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 23118056 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 19258083 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17216477 — Surrogate Endpoint (SUR): Bone mineral density
Study 25029703 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24130351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9989311 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 25994179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20598444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20598444 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12720590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9076452 — Safety Biomarker (SAF): Hyaluronic acid
Study 8439828 — Surrogate Endpoint (SUR): Blood pressure
Study 10341672 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23014489 — Predictive Biomarker (PRD): LAT2 mRNA
Genes: LAT2; LAB; NTAL; WBS15; WBSCR15; WBSCR5; HSPC046
Study 23014489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17678776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17678776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22342916 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 7848930 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3907037 — Surrogate Endpoint (SUR): Serum sodium
Study 10220011 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23273538 — Predictive Biomarker (PRD): Chromosome 5q
Study 8204940 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8204940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23642372 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19451297 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10924375 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3907288 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30256758 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 17156651 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17156651 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17156651 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31407856 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 31407856 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11589384 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 31084259 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9277416 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3179922 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1163469 — Surrogate Endpoint (SUR): Serum calcium
Study 25793988 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 23706051 — Surrogate Endpoint (SUR): Blood pressure
Study 19632695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14686965 — Surrogate Endpoint (SUR): Blood pressure
Study 14686965 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23866979 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 16952987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16952987 — Surrogate Endpoint (SUR): Blood pressure
Study 16952987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11275039 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25304725 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3046385 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 28939589 — Surrogate Endpoint (SUR): Blood pressure
Study 25386711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2494397 — Surrogate Endpoint (SUR): Blood pressure
Study 56146 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 23065659 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 23065659 — Surrogate Endpoint (SUR): Blood pressure
Study 8160720 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8160720 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31892263 — Surrogate Endpoint (SUR): Blood pressure
Study 18471512 — Surrogate Endpoint (SUR): Serum creatinine
Study 25640037 — Surrogate Endpoint (SUR): Blood pressure
Study 12196659 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10503860 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24980290 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 7766324 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9613379 — Surrogate Endpoint (SUR): Blood pressure
Study 326034 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27906839 — Surrogate Endpoint (SUR): Blood pressure
Study 26041745 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26041745 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26041745 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 16113459 — Predictive Biomarker (PRD): CRHR1 mRNA
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 29324705 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29324705 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 14685749 — Surrogate Endpoint (SUR): Blood pressure
Study 8028506 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 8028506 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8028506 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21637908 — Safety Biomarker (SAF): Hyaluronic acid
Study 11824325 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 7818058 — Surrogate Endpoint (SUR): Blood pressure
Study 15915010 — Surrogate Endpoint (SUR): Blood pressure
Study 12409652 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 31769533 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28117400 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 28117400 — Surrogate Endpoint (SUR): Blood pressure
Study 23702253 — Surrogate Endpoint (SUR): Blood pressure
Study 23702253 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17953695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17953695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24565698 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 12243291 — Surrogate Endpoint (SUR): Blood pressure
Study 10328327 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1963183 — Surrogate Endpoint (SUR): Blood pressure
Study 12628531 — Surrogate Endpoint (SUR): Blood pressure
Study 7682427 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 7682427 — Predictive Biomarker (PRD): HLA-DMB mRNA
Genes: HLA-DMB; DMB; RING7
Study 27096580 — Surrogate Endpoint (SUR): Blood pressure
Study 15630410 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 15630410 — Safety Biomarker (SAF): BDNF
Study 6637574 — Surrogate Endpoint (SUR): Blood pressure
Study 31146326 — Surrogate Endpoint (SUR): Blood pressure
Study 19528843 — Predictive Biomarker (PRD): NINL mRNA
Genes: NINL; KIAA0980; NLP
Study 15600245 — Predictive Biomarker (PRD): STT3A mRNA
Genes: STT3A; ITM1; TMC
Study 9498972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9498972 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31522376 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22863660 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9626637 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9626637 — Surrogate Endpoint (SUR): Bone mineral density
Study 31954199 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30659702 — Surrogate Endpoint (SUR): Blood pressure
Study 25559659 — Safety Biomarker (SAF): Reactive oxygen species
Study 15133849 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15133849 — Monitoring Biomarker (MOI): HBV DNA
Study 11481387 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9504446 — Surrogate Endpoint (SUR): Blood pressure
Study 19633475 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16752169 — Predictive Biomarker (PRD): APOA5 mRNA
Genes: APOA5; RAP3; UNQ411/PRO773
Study 16752169 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 16752169 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11942734 — Safety Biomarker (SAF): Reactive oxygen species
Study 26853341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26853341 — Safety Biomarker (SAF): Interleukin 1
Study 18563435 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11872916 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10510145 — Surrogate Endpoint (SUR): Blood pressure
Study 11352373 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9671370 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 31578168 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23640486 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22093195 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19236773 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19236773 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 19236773 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 19236773 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 23663658 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23663658 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17346425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17346425 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 17346425 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17346425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24151693 — Surrogate Endpoint (SUR): Blood pressure
Study 14551493 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31182401 — Surrogate Endpoint (SUR): Blood pressure
Study 29242283 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25022113 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17400142 — Surrogate Endpoint (SUR): Blood pressure
Study 16264158 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 376950 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 19563586 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10698386 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10698386 — Surrogate Endpoint (SUR): Blood pressure
Study 23356032 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15593392 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17122083 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 17122083 — Predictive Biomarker (PRD): IGF2R mRNA
Genes: IGF2R; MPRI
Study 1745027 — Surrogate Endpoint (SUR): Serum creatinine
Study 31640891 — Surrogate Endpoint (SUR): Blood pressure
Study 26727115 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 24903351 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 19229988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17698116 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8677757 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8677757 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8677757 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29602597 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29602597 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25332243 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16311849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28263919 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30350398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8966498 — Surrogate Endpoint (SUR): Bone mineral density
Study 27123421 — Surrogate Endpoint (SUR): Blood pressure
Study 18161210 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12452452 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 6303106 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 27078993 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 15126518 — Surrogate Endpoint (SUR): Serum testosterone
Study 11044760 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25249036 — Surrogate Endpoint (SUR): Blood pressure
Study 23121733 — Surrogate Endpoint (SUR): Serum creatinine
Study 28901958 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 28901958 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24429202 — Surrogate Endpoint (SUR): Bone mineral density
Study 10766405 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22454189 — Surrogate Endpoint (SUR): Blood pressure
Study 22454189 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16254220 — Surrogate Endpoint (SUR): Blood pressure
Study 27762648 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27762648 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27762648 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 15542798 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15542798 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9316778 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 9316778 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 31209428 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 23030566 — Surrogate Endpoint (SUR): Blood pressure
Study 19959271 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12494164 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6781794 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 15452587 — Predictive Biomarker (PRD): GPR50 mRNA
Genes: GPR50
Study 29596951 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25639838 — Surrogate Endpoint (SUR): Bone mineral density
Study 16978159 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2691690 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2691690 — Surrogate Endpoint (SUR): Blood pressure
Study 241364 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 25190674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23232491 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 23232491 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 23232491 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 8399073 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2868549 — Surrogate Endpoint (SUR): Blood pressure
Study 22784926 — Surrogate Endpoint (SUR): Blood pressure
Study 20584682 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS