TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10774766 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7721921 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1790147 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23958221 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23958221 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23958221 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 23958221 — Predictive Biomarker (PRD): Hormone receptor
Study 23181690 — Surrogate Endpoint (SUR): Blood pressure
Study 7921858 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7921858 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 7921858 — Surrogate Endpoint (SUR): Blood pressure
Study 31713184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24284618 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11132743 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9296895 — Surrogate Endpoint (SUR): Blood pressure
Study 3946161 — Surrogate Endpoint (SUR): Blood pressure
Study 23104611 — Safety Biomarker (SAF): Hyaluronic acid
Study 16234118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17397003 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 17397003 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 8745496 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 28945869 — Predictive Biomarker (PRD): STC2 mRNA
Genes: STC2
Study 28945869 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 26323489 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23622911 — Safety Biomarker (SAF): Reactive oxygen species
Study 1534716 — Surrogate Endpoint (SUR): Blood pressure
Study 31364875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28088806 — Safety Biomarker (SAF): Hyaluronic acid
Study 22356799 — Surrogate Endpoint (SUR): Blood pressure
Study 26074359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21235787 — Surrogate Endpoint (SUR): Blood pressure
Study 30801532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30840384 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 22695241 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22695241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2643282 — Surrogate Endpoint (SUR): Blood pressure
Study 31034084 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 27988142 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 27988142 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 27988142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27988142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24165696 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22204799 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 8064075 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31828287 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22583007 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 17550933 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26289076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18360018 — Surrogate Endpoint (SUR): Blood pressure
Study 18360018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11445757 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 11445757 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 3285833 — Surrogate Endpoint (SUR): Blood pressure
Study 3285833 — Surrogate Endpoint (SUR): Serum potassium
Study 15090799 — Surrogate Endpoint (SUR): Blood pressure
Study 9743817 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 20508338 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 20508338 — Surrogate Endpoint (SUR): Serum calcium
Study 18829995 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 8579031 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 25995282 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 17524997 — Surrogate Endpoint (SUR): Bone mineral density
Study 15545824 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 15545824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15545824 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 11350567 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11350567 — Surrogate Endpoint (SUR): Blood pressure
Study 2139843 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 2139843 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 28983938 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 27657522 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27657522 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27874299 — Surrogate Endpoint (SUR): Blood pressure
Study 24780728 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 27481881 — Surrogate Endpoint (SUR): Blood pressure
Study 23488690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23488690 — Surrogate Endpoint (SUR): Blood pressure
Study 17425758 — Surrogate Endpoint (SUR): Blood pressure
Study 17425758 — Surrogate Endpoint (SUR): Serum creatinine
Study 17425758 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15781019 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28685542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28685542 — Safety Biomarker (SAF): IL-6 and IL-10
Study 28685542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28685542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10782840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9324342 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 22105574 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17220631 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 17220631 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11122756 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7930385 — Surrogate Endpoint (SUR): Blood pressure
Study 23710960 — Safety Biomarker (SAF): Hyaluronic acid
Study 21838913 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11433674 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 7599759 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 359215 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31804894 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24232362 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 16996948 — Surrogate Endpoint (SUR): Blood pressure
Study 14535968 — Surrogate Endpoint (SUR): Blood pressure
Study 30865796 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17379047 — Surrogate Endpoint (SUR): Blood pressure
Study 10190880 — Surrogate Endpoint (SUR): Blood pressure
Study 11527135 — Surrogate Endpoint (SUR): Blood pressure
Study 6127907 — Surrogate Endpoint (SUR): Blood pressure
Study 31500444 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 31500444 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7795397 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7795397 — Surrogate Endpoint (SUR): Blood pressure
Study 23172127 — Surrogate Endpoint (SUR): Blood pressure
Study 23172127 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21889769 — Predictive Biomarker (PRD): APOA5 mRNA
Genes: APOA5; RAP3; UNQ411/PRO773
Study 21889769 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21889769 — Predictive Biomarker (PRD): ZPR1 mRNA
Genes: ZPR1; ZNF259
Study 21889769 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21889769 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18066566 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 12780945 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8882114 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6501237 — Surrogate Endpoint (SUR): Blood pressure
Study 24645800 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24645800 — Predictive Biomarker (PRD): NDRG4 mRNA
Genes: NDRG4; BDM1; KIAA1180
Study 24645800 — Predictive Biomarker (PRD): BMP3 mRNA
Genes: BMP3; BMP3A
Study 22503057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17587750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17587750 — Surrogate Endpoint (SUR): Blood pressure
Study 29083477 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 26906034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26906034 — Safety Biomarker (SAF): Interleukin 1
Study 24694077 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 12516831 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 11938780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8572785 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27886382 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27886382 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26186444 — Surrogate Endpoint (SUR): Blood pressure
Study 15320983 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9118772 — Surrogate Endpoint (SUR): Blood pressure
Study 24799608 — Surrogate Endpoint (SUR): Blood pressure
Study 22650119 — Surrogate Endpoint (SUR): Blood pressure
Study 22650119 — Surrogate Endpoint (SUR): Serum creatinine
Study 20980427 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20980427 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18614167 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12027564 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23650416 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21741642 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 19359813 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 15858257 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11062381 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31812946 — Surrogate Endpoint (SUR): Blood pressure
Study 28230639 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11560566 — Surrogate Endpoint (SUR): Blood pressure
Study 23032417 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20919540 — Surrogate Endpoint (SUR): Blood pressure
Study 18431264 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17075113 — Predictive Biomarker (PRD): Hormone receptor
Study 11200917 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 11200917 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1377118 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1377118 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31005969 — Surrogate Endpoint (SUR): Serum calcium
Study 19449344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11208681 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8500862 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29587666 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18639628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18639628 — Surrogate Endpoint (SUR): Blood pressure
Study 31795482 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 22293126 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 22293126 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22293126 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 22293126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22293126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22293126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22293126 — Surrogate Endpoint (SUR): Bone mineral density
Study 17234506 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17234506 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16847182 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11030848 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29763373 — Surrogate Endpoint (SUR): Blood pressure
Study 18245179 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 1643676 — Surrogate Endpoint (SUR): Blood pressure
Study 31171878 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 24628035 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 24628035 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19200119 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 3533567 — Surrogate Endpoint (SUR): Blood pressure
Study 20884014 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20884014 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 17317388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 3723158 — Surrogate Endpoint (SUR): Blood pressure
Study 24560278 — Predictive Biomarker (PRD): MT1F mRNA
Genes: MT1F; PRO0376
Study 24560278 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 22527372 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 10995004 — Predictive Biomarker (PRD): RARS1 mRNA
Genes: RARS1; RARS
Study 26963952 — Surrogate Endpoint (SUR): Serum testosterone
Study 1290634 — Surrogate Endpoint (SUR): Serum calcium
Study 3937509 — Surrogate Endpoint (SUR): Blood pressure
Study 30785667 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 16038474 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10708161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9396090 — Surrogate Endpoint (SUR): Blood pressure
Study 2680795 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 25458645 — Surrogate Endpoint (SUR): Blood pressure
Study 17542406 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 29864505 — Surrogate Endpoint (SUR): Blood pressure
Study 9790269 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 29239982 — Surrogate Endpoint (SUR): Blood pressure
Study 28731609 — Surrogate Endpoint (SUR): Blood pressure
Study 25434837 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 22762449 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 19627212 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10741628 — Surrogate Endpoint (SUR): Blood pressure
Study 10100788 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23546553 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23546553 — Predictive Biomarker (PRD): Hormone receptor
Study 20031847 — Surrogate Endpoint (SUR): Blood pressure
Study 31106666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28639089 — Surrogate Endpoint (SUR): Blood pressure
Study 26940720 — Surrogate Endpoint (SUR): Bone mineral density
Study 22533447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7705375 — Surrogate Endpoint (SUR): Bone mineral density
Study 23538020 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20655105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14573327 — Surrogate Endpoint (SUR): Blood pressure
Study 14573327 — Surrogate Endpoint (SUR): Serum creatinine
Study 30113051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22115970 — Surrogate Endpoint (SUR): Blood pressure
Study 18771430 — Surrogate Endpoint (SUR): Serum creatinine
Study 18322604 — Monitoring Biomarker (MOI): HBV DNA
Study 15010365 — Surrogate Endpoint (SUR): Bone mineral density
Study 11588457 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11588457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1639051 — Surrogate Endpoint (SUR): Blood pressure
Study 16471172 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12742806 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25350851 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17917517 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10427933 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31931928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31931928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31931928 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 24844352 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 16878429 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8888663 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8888663 — Surrogate Endpoint (SUR): Blood pressure
Study 8888663 — Surrogate Endpoint (SUR): Serum potassium
Study 8888663 — Surrogate Endpoint (SUR): Serum creatinine
Study 28645983 — Surrogate Endpoint (SUR): Bone mineral density
Study 25890643 — Safety Biomarker (SAF): DRD2
Study 18423151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18423151 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18423151 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 18423151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18423151 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 18423151 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19051099 — Surrogate Endpoint (SUR): Blood pressure
Study 14694529 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 14694529 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12586855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12586855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15952055 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12575964 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 12037652 — Surrogate Endpoint (SUR): Blood pressure
Study 10194172 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25837980 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 25837980 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 25837980 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 25837980 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25837980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21439397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11920277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23828452 — Surrogate Endpoint (SUR): Blood pressure
Study 20335146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18710018 — Surrogate Endpoint (SUR): Blood pressure
Study 15625368 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3934948 — Surrogate Endpoint (SUR): Blood pressure