TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31265338 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 23602843 — Safety Biomarker (SAF): Hyaluronic acid
Study 18785544 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10982541 — Surrogate Endpoint (SUR): Blood pressure
Study 21141077 — Surrogate Endpoint (SUR): Blood pressure
Study 16140593 — Surrogate Endpoint (SUR): Blood pressure
Study 12145765 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 7638685 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7638685 — Surrogate Endpoint (SUR): Serum creatinine
Study 7638685 — Surrogate Endpoint (SUR): Blood pressure
Study 7638685 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 31270297 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 25722381 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 25722381 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study 25722381 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 7865492 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 8777337 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8777337 — Safety Biomarker (SAF): Urinary microalbumin
Study 1836220 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27422216 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25341673 — Safety Biomarker (SAF): Hyaluronic acid
Study 22870265 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12392825 — Safety Biomarker (SAF): Reactive oxygen species
Study 12392825 — Surrogate Endpoint (SUR): Serum creatinine
Study 8697727 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 8697727 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 8697727 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 2179754 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 2179754 — Surrogate Endpoint (SUR): Serum creatinine
Study 2179754 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19144734 — Surrogate Endpoint (SUR): Blood pressure
Study 30204768 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30204768 — Surrogate Endpoint (SUR): Blood pressure
Study 27424036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30474011 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 24380397 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17609401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28005623 — Safety Biomarker (SAF): Hyaluronic acid
Study 22333250 — Surrogate Endpoint (SUR): Serum creatinine
Study 8310977 — Surrogate Endpoint (SUR): Blood pressure
Study 24094008 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 7576676 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7576676 — Surrogate Endpoint (SUR): Blood pressure
Study 31501084 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29847486 — Surrogate Endpoint (SUR): Blood pressure
Study 20102927 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7605858 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 28202686 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24070181 — Surrogate Endpoint (SUR): Blood pressure
Study 9854471 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9854471 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 9854471 — Predictive Biomarker (PRD): CDKN1A mRNA
Genes: CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1
Study 2132641 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 20638463 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 15269313 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9751064 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10806282 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27178854 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 23579106 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 1583761 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 17922666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16111487 — Surrogate Endpoint (SUR): Blood pressure
Study 12098721 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24192386 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23326213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23326213 — Surrogate Endpoint (SUR): Blood pressure
Study 2913776 — Surrogate Endpoint (SUR): Blood pressure
Study 2913776 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30449812 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25268878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25268878 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 25268878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25268878 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16850439 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 9247755 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9247755 — Surrogate Endpoint (SUR): Blood pressure
Study 8100928 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28606702 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28606702 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27574999 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 24597465 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24597465 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 10651074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10651074 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10651074 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 8754409 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 8754409 — Predictive Biomarker (PRD): NAAA mRNA
Genes: NAAA; ASAHL; PLT
Study 8754409 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11912561 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11912561 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8880382 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28103819 — Monitoring Biomarker (MOI): HBV DNA
Study 26016867 — Surrogate Endpoint (SUR): Blood pressure
Study 20926968 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 20926968 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15650348 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15650348 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11562516 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30942033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28197716 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 25770758 — Surrogate Endpoint (SUR): Blood pressure
Study 19192991 — Surrogate Endpoint (SUR): Serum potassium
Study 14530858 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29058057 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22289248 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 22289248 — Surrogate Endpoint (SUR): Blood pressure
Study 21480491 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 18615232 — Surrogate Endpoint (SUR): Bone mineral density
Study 20132529 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17132920 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 23965522 — Surrogate Endpoint (SUR): Serum creatinine
Study 16171667 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16171667 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16171667 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31952131 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22011409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22011409 — Surrogate Endpoint (SUR): Blood pressure
Study 19293069 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15902475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15902475 — Safety Biomarker (SAF): Interleukin 1
Study 15902475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15902475 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15902475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1533168 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1533168 — Surrogate Endpoint (SUR): Blood pressure
Study 19229379 — Surrogate Endpoint (SUR): Blood pressure
Study 23450052 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 10073783 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24329913 — Monitoring Biomarker (MOI): HBV DNA
Study 18797697 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15736995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10525131 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2373273 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22545565 — Predictive Biomarker (PRD): TAL1 mRNA
Genes: TAL1; BHLHA17; SCL; TCL5
Study 21279932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16238586 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16238586 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 16238586 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12030918 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 12030918 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 12030918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12030918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12030918 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31927716 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28538111 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 28538111 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28538111 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12637625 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9232087 — Surrogate Endpoint (SUR): Bone mineral density
Study 2676174 — Surrogate Endpoint (SUR): Blood pressure
Study 26023227 — Surrogate Endpoint (SUR): Blood pressure
Study 23473847 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16846551 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15670201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15670201 — Surrogate Endpoint (SUR): Serum testosterone
Study 15670201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15670201 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15670201 — Surrogate Endpoint (SUR): Serum triglycerides
Study 3294920 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 26805417 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 17058827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17058827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17058827 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17058827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8314358 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8314358 — Surrogate Endpoint (SUR): Blood pressure
Study 30539289 — Predictive Biomarker (PRD): IMMT mRNA
Genes: IMMT; HMP; MIC60; MINOS2; PIG4; PIG52
Study 17715049 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7889236 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 28853303 — Surrogate Endpoint (SUR): Blood pressure
Study 23562009 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 23562009 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19921354 — Surrogate Endpoint (SUR): Blood pressure
Study 9129961 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6445225 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26341820 — Surrogate Endpoint (SUR): Blood pressure
Study 22668675 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 31595044 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 8617907 — Surrogate Endpoint (SUR): Blood pressure
Study 1320536 — Surrogate Endpoint (SUR): Blood pressure
Study 24702987 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24702987 — Safety Biomarker (SAF): BDNF
Study 9088587 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3883843 — Surrogate Endpoint (SUR): Blood pressure
Study 30234415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30234415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30234415 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18983246 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23592676 — Surrogate Endpoint (SUR): Blood pressure
Study 15279069 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 15279069 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17130203 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17130203 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 3317340 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3317340 — Surrogate Endpoint (SUR): Blood pressure
Study 2528492 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 28807505 — Surrogate Endpoint (SUR): Serum testosterone
Study 21347224 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10225169 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28128967 — Surrogate Endpoint (SUR): Blood pressure
Study 15517308 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15517308 — Surrogate Endpoint (SUR): Blood pressure
Study 7574044 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7574044 — Surrogate Endpoint (SUR): Serum uric acid
Study 31769212 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 30583949 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30583949 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30583949 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 9398007 — Monitoring Biomarker (MOI): HBV DNA
Study 8177627 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3221935 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 28671712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28671712 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 28671712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19073509 — Surrogate Endpoint (SUR): Bone mineral density
Study 23822684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2820920 — Surrogate Endpoint (SUR): Blood pressure
Study 26834213 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 24315152 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20607528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20607528 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20607528 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10952955 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3781687 — Safety Biomarker (SAF): L-acetylcarnitine
Study 18089703 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30761720 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27647021 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27647021 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 27647021 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27647021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26544853 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22351480 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 30253197 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30253197 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 30253197 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 31656094 — Surrogate Endpoint (SUR): Blood pressure
Study 22137666 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11291084 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11291084 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11291084 — Pharmacodynamic Biomarker (PDY): RAS peptides
Study 1093464 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 19365652 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16704952 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15081455 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 15081455 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15081455 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7899862 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 28049642 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study 28049642 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 23063625 — Safety Biomarker (SAF): Hyaluronic acid
Study 21750266 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 21750266 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19401659 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 15290395 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 9469797 — Surrogate Endpoint (SUR): Blood pressure
Study 9469797 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8194494 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21906391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21906391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3883767 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19037084 — Surrogate Endpoint (SUR): Blood pressure
Study 9551877 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9551877 — Surrogate Endpoint (SUR): Blood pressure
Study 26873681 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26873681 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 26873681 — Surrogate Endpoint (SUR): Blood pressure
Study 25046547 — Surrogate Endpoint (SUR): Bone mineral density
Study 16866686 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 3937598 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22613197 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 7491697 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 7491697 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25719984 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25093483 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 2888417 — Surrogate Endpoint (SUR): Blood pressure
Study 31986451 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31986451 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 31986451 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 27248716 — Surrogate Endpoint (SUR): Blood pressure
Study 21347737 — Surrogate Endpoint (SUR): Blood pressure
Study 12749508 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23179471 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21502083 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21502083 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 21502083 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 17848760 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29359480 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 29359480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29359480 — Safety Biomarker (SAF): Interleukin 1