TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03256136 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01245231 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study NCT00425945 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04389268 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT01099761 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01099761 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04533516 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT02797470 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02797470 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00730210 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03604289 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04112355 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study NCT04112355 — Safety Biomarker (SAF): Interleukin 1
Study NCT00899860 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study NCT02652546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04135664 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study NCT02450123 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT02450123 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT00634088 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00634088 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01896414 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03840200 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04428983 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT00014495 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT01414023 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02845999 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02845999 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00168168 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03824964 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03824964 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT01819428 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03209986 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02448797 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02110225 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT00962221 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02592746 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02592746 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01911897 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05593094 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01359891 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT01359891 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study NCT01359891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00640315 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00640315 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00640315 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00199147 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00455156 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study NCT02802904 — Safety Biomarker (SAF): Glycerol backbone
Study NCT02802904 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT06063525 — Predictive Biomarker (PRD): PRKN mRNA
Genes: PRKN; PARK2
Study NCT04010552 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01747824 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02756741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02160327 — Predictive Biomarker (PRD): SLK mRNA
Genes: SLK; KIAA0204; STK2
Study NCT02274506 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02274506 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03096158 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03096158 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03335514 — Predictive Biomarker (PRD): GALNT4 mRNA
Genes: GALNT4
Study NCT03335514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01461538 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT04413201 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01791465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01791465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00403585 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00441220 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01966991 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT01966991 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02532309 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02533076 — Predictive Biomarker (PRD): CTNS mRNA
Genes: CTNS
Study NCT02533076 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT02106234 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02808416 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT01240486 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00411411 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00411411 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02163668 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00459043 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00459043 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT00459043 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00459043 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02982837 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04176276 — Safety Biomarker (SAF): miR-192
Genes: MIR192
Study NCT04176276 — Predictive Biomarker (PRD): miR-25
Genes: MIR25
Study NCT02798588 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT03438019 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT01783886 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03305367 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01525524 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00006073 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT00006073 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00006073 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00006073 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study NCT01806571 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT00347386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02552121 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT02430480 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02430480 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03440125 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT00316758 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study NCT00425204 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02368418 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00739063 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00739063 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00931645 — Predictive Biomarker (PRD): ZAP70 mRNA
Genes: ZAP70; SRK
Study NCT00931645 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT01301729 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02537691 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02537691 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT04317092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01377818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01377818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02921113 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study NCT04174612 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT03660280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04201197 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT04201197 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04201197 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT04201197 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02829476 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study NCT04064944 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT00588380 — Predictive Biomarker (PRD): GLP1R mRNA
Genes: GLP1R
Study NCT03748420 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00928044 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00039091 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00341393 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03698929 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01442090 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00736450 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT04383535 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03649139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00184067 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02118636 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03458988 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01921699 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02046603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02046603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03552900 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00470977 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00470977 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02899195 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00663689 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00763607 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study NCT01462591 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03582865 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01464398 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02353325 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00270855 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00270855 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04201730 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT02879344 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT04520919 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01108627 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study NCT03718923 — Predictive Biomarker (PRD): FOXP1 mRNA
Genes: FOXP1; HSPC215
Study NCT05472376 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05472376 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00131599 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT02076243 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT03140657 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03140657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03140657 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT03140657 — Predictive Biomarker (PRD): miR-17
Genes: MIR17
Study NCT03140657 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study NCT00945269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT00176072 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT02240992 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02583711 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00419835 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03797885 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03797885 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05151289 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02129608 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01319045 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00706056 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02062970 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT01973387 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03557502 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06409507 — Predictive Biomarker (PRD): FKBP1A mRNA
Genes: FKBP1A; FKBP1; FKBP12
Study NCT02096471 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT04864327 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05478967 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06107790 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01446991 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT02907411 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study NCT02669446 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01892241 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04050215 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02128958 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study NCT01266070 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT04462978 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT01328769 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01328769 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00802724 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT02314286 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02433691 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03632915 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00112567 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02245880 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04062006 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02082665 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT02082665 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT05155839 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04410835 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03339830 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00257322 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04446494 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT04446494 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT00574366 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study NCT00574366 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03146104 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03705741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03705741 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04450004 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03210467 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study NCT00948194 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study NCT03718468 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT04264910 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study NCT03288623 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study NCT03288623 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT00921570 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study NCT00921570 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study NCT00921570 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01095939 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00442130 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01737138 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00384449 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00732472 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03557229 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT02253394 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01968083 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02117791 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03336203 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT01307046 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03052465 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT03052465 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT01040728 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00415623 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02637167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01751204 — Surrogate Endpoint (SUR): Serum calcium
Study NCT04685655 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02545517 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01495260 — Predictive Biomarker (PRD): AMN mRNA
Genes: AMN; UNQ513/PRO1028
Study NCT00289614 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02986867 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study NCT02978872 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT03968211 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00004141 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04639505 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01952613 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT04255992 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00871195 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT02736929 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04233840 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03872336 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02743975 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02743975 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02967640 — Predictive Biomarker (PRD): GRIN1 mRNA
Genes: GRIN1; NMDAR1
Study NCT03216980 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00796549 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01522196 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01522196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00596895 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00951119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00954824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2