TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27870723 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 25434303 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 19136900 — Surrogate Endpoint (SUR): Serum creatinine
Study 19136900 — Surrogate Endpoint (SUR): Blood pressure
Study 17878480 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19549996 — Surrogate Endpoint (SUR): Bone mineral density
Study 29982608 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 29982608 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19160404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19160404 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19160404 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19160404 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 19160404 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19160404 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19160404 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 11961245 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31122062 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12238431 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 9638033 — Surrogate Endpoint (SUR): Blood pressure
Study 8206809 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8206809 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 2536517 — Surrogate Endpoint (SUR): Blood pressure
Study 26269215 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 26269215 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26269215 — Surrogate Endpoint (SUR): Blood pressure
Study 23244536 — Surrogate Endpoint (SUR): Bone mineral density
Study 10910540 — Surrogate Endpoint (SUR): Serum potassium
Study 8083823 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 28985268 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 28985268 — Surrogate Endpoint (SUR): Blood pressure
Study 6308685 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6308685 — Surrogate Endpoint (SUR): Blood pressure
Study 25171056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9216117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9216117 — Surrogate Endpoint (SUR): Serum uric acid
Study 28025374 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23902874 — Predictive Biomarker (PRD): Hormone receptor
Study 18752381 — Surrogate Endpoint (SUR): Blood pressure
Study 17058629 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17058629 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17058629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29659684 — Surrogate Endpoint (SUR): Blood pressure
Study 15710335 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 10520212 — Safety Biomarker (SAF): MTHFR
Study 7554180 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 19122337 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11684627 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2689469 — Surrogate Endpoint (SUR): Blood pressure
Study 30444838 — Surrogate Endpoint (SUR): Blood pressure
Study 26073022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24125483 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 24125483 — Surrogate Endpoint (SUR): Blood pressure
Study 7667832 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 28279941 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15492789 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15492789 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8049437 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 8049437 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 8049437 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 8049437 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 8049437 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study 8049437 — Predictive Biomarker (PRD): CD9 mRNA
Genes: CD9; MIC3; TSPAN29; GIG2
Study 8049437 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8049437 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8049437 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 30131049 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12692009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12692009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7852106 — Predictive Biomarker (PRD): TOX mRNA
Genes: TOX; KIAA0808
Study 19123877 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 12871456 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 8895943 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8895943 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 24251881 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 24251881 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 21987535 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8721461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1824527 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 29572761 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19129277 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19129277 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31282954 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25399822 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 23451258 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21730007 — Surrogate Endpoint (SUR): Blood pressure
Study 19191893 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 16510864 — Surrogate Endpoint (SUR): Blood pressure
Study 8450520 — Surrogate Endpoint (SUR): Blood pressure
Study 16088104 — Surrogate Endpoint (SUR): Blood pressure
Study 16088104 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19587123 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19587123 — Surrogate Endpoint (SUR): Blood pressure
Study 18021533 — Monitoring Biomarker (MOI): HBV DNA
Study 707354 — Surrogate Endpoint (SUR): Serum sodium
Study 21366361 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 21366361 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11743900 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7950222 — Predictive Biomarker (PRD): GNS mRNA
Genes: GNS
Study 7950222 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25656169 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23021943 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10997375 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10997375 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 10997375 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8782501 — Surrogate Endpoint (SUR): Blood pressure
Study 1600777 — Surrogate Endpoint (SUR): Blood pressure
Study 17587715 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17587715 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20724131 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2059395 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2059395 — Surrogate Endpoint (SUR): Blood pressure
Study 30861219 — Surrogate Endpoint (SUR): Bone mineral density
Study 25875779 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 19820286 — Surrogate Endpoint (SUR): Serum creatinine
Study 18543495 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12014437 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12014437 — Surrogate Endpoint (SUR): Bone mineral density
Study 7174801 — Surrogate Endpoint (SUR): Blood pressure
Study 31654779 — Surrogate Endpoint (SUR): Bone mineral density
Study 26453327 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26453327 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 26453327 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 26453327 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 19300423 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19300423 — Surrogate Endpoint (SUR): Blood pressure
Study 17201808 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7946163 — Surrogate Endpoint (SUR): Serum potassium
Study 23512639 — Surrogate Endpoint (SUR): Blood pressure
Study 20518254 — Predictive Biomarker (PRD): ALPK3 mRNA
Genes: ALPK3; KIAA1330; MAK
Study 15971460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1827125 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 6261782 — Surrogate Endpoint (SUR): Blood pressure
Study 19049481 — Surrogate Endpoint (SUR): Serum sodium
Study 19049481 — Surrogate Endpoint (SUR): Serum creatinine
Study 19049481 — Surrogate Endpoint (SUR): Serum potassium
Study 8817982 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8817982 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 8817982 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8817982 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1597852 — Surrogate Endpoint (SUR): Blood pressure
Study 1375678 — Surrogate Endpoint (SUR): Blood pressure
Study 18670740 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18670740 — Surrogate Endpoint (SUR): Blood pressure
Study 16440578 — Surrogate Endpoint (SUR): Serum calcium
Study 29505471 — Predictive Biomarker (PRD): CRHR1 mRNA
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 27178257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3209280 — Surrogate Endpoint (SUR): Blood pressure
Study 25154982 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25154982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20818474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20818474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2567483 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23792400 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15072892 — Surrogate Endpoint (SUR): Serum testosterone
Study 2941267 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23039014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18353996 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18353996 — Surrogate Endpoint (SUR): Blood pressure
Study 7586783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7586783 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23642378 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23642378 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17578484 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study 15223721 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15223721 — Surrogate Endpoint (SUR): Blood pressure
Study 9161624 — Surrogate Endpoint (SUR): Blood pressure
Study 8125423 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26892006 — Surrogate Endpoint (SUR): Blood pressure
Study 22303708 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9248982 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30428134 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23439415 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 23439415 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23439415 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23439415 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28407148 — Surrogate Endpoint (SUR): Blood pressure
Study 26692347 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 22705017 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 15755572 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29790612 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 29023508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29023508 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26035431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26035431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 690225 — Surrogate Endpoint (SUR): Blood pressure
Study 31418966 — Surrogate Endpoint (SUR): Blood pressure
Study 16181380 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 16181380 — Predictive Biomarker (PRD): HLTF mRNA
Genes: HLTF; HIP116A; RNF80; SMARCA3; SNF2L3; ZBU1
Study 14566763 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 14566763 — Surrogate Endpoint (SUR): Serum calcium
Study 17909351 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 20004758 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 16625281 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 16625281 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 14659774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14659774 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2687897 — Surrogate Endpoint (SUR): Blood pressure
Study 19029466 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19029466 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19029466 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19029466 — Surrogate Endpoint (SUR): Serum sodium
Study 19029466 — Surrogate Endpoint (SUR): Serum potassium
Study 31968080 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31968080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31274110 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28892265 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 28892265 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19414437 — Surrogate Endpoint (SUR): Blood pressure
Study 19414437 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16388944 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11156281 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24488721 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 17241782 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 16189333 — Surrogate Endpoint (SUR): Blood pressure
Study 14621278 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 14621278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9007457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9007457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17609248 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8130028 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1161344 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 15219636 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1770216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31086050 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 31086050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31086050 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 25227543 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 10520778 — Surrogate Endpoint (SUR): Blood pressure
Study 30970430 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 22145450 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 16855462 — Surrogate Endpoint (SUR): Blood pressure
Study 12616671 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25524227 — Surrogate Endpoint (SUR): Bone mineral density
Study 21147414 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 17106543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17106543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17106543 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20836133 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11029555 — Safety Biomarker (SAF): Hyaluronic acid
Study 3514487 — Surrogate Endpoint (SUR): Blood pressure
Study 3514487 — Surrogate Endpoint (SUR): Serum potassium
Study 15679718 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12895452 — Safety Biomarker (SAF): Cytochrome c
Study 30599803 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 26273669 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21609640 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 27635609 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 27635609 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27635609 — Safety Biomarker (SAF): BDNF
Study 23350203 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 21950726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21950726 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7942937 — Surrogate Endpoint (SUR): Blood pressure
Study 8447567 — Surrogate Endpoint (SUR): Blood pressure
Study 3082613 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26328636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26328636 — Surrogate Endpoint (SUR): Serum uric acid
Study 26328636 — Surrogate Endpoint (SUR): Blood pressure
Study 21798556 — Surrogate Endpoint (SUR): Blood pressure
Study 11382830 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 8299238 — Surrogate Endpoint (SUR): Serum creatinine
Study 8299238 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20598373 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 19096768 — Predictive Biomarker (PRD): Hormone receptor
Study 10229430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8709356 — Surrogate Endpoint (SUR): Serum creatinine
Study 15814542 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9453014 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 9453014 — Predictive Biomarker (PRD): MOXD1 mRNA
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 9453014 — Surrogate Endpoint (SUR): Blood pressure
Study 7615046 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 31554370 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 27522630 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 24492988 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 18445142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10618463 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 22042967 — Predictive Biomarker (PRD): Hormone receptor
Study 9649964 — Surrogate Endpoint (SUR): Blood pressure
Study 28474780 — Surrogate Endpoint (SUR): Bone mineral density
Study 24576893 — Surrogate Endpoint (SUR): Serum potassium
Study 28975305 — Surrogate Endpoint (SUR): Blood pressure
Study 23343138 — Surrogate Endpoint (SUR): Blood pressure
Study 17225260 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 9587124 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA