TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7594155 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1428381 — Surrogate Endpoint (SUR): Blood pressure
Study 28786530 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20375180 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10397563 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7547093 — Safety Biomarker (SAF): CYP2C9
Genes: P450IIC9
Study 17228021 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 11939614 — Surrogate Endpoint (SUR): Blood pressure
Study 9637639 — Surrogate Endpoint (SUR): Blood pressure
Study 21146460 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 21146460 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 22825497 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 694829 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30905157 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 30155718 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29269731 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29668213 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26913411 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26913411 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 7948450 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 10853616 — Surrogate Endpoint (SUR): Blood pressure
Study 10929902 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9352392 — Surrogate Endpoint (SUR): Blood pressure
Study 12702735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10680106 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30836804 — Surrogate Endpoint (SUR): Blood pressure
Study 21946392 — Surrogate Endpoint (SUR): Blood pressure
Study 21946392 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17721009 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31581815 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 21147163 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 15088870 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8675159 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31740426 — Predictive Biomarker (PRD): TXNIP mRNA
Genes: TXNIP; VDUP1
Study 31740426 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 21950312 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21950312 — Surrogate Endpoint (SUR): Blood pressure
Study 15637459 — Surrogate Endpoint (SUR): Blood pressure
Study 15637459 — Surrogate Endpoint (SUR): Serum creatinine
Study 27907978 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 18457886 — Surrogate Endpoint (SUR): Blood pressure
Study 10705179 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 24793816 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 1460750 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 23763990 — Safety Biomarker (SAF): RAS pathway
Study 19595251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19595251 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19595251 — Safety Biomarker (SAF): Human leucocyte antigen
Study 16817289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16850006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11230282 — Surrogate Endpoint (SUR): Blood pressure
Study 14663654 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 11380294 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9409274 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9409274 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3681277 — Surrogate Endpoint (SUR): Blood pressure
Study 31647775 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 2498449 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 24358625 — Predictive Biomarker (PRD): RARS1 mRNA
Genes: RARS1; RARS
Study 21685533 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 21685533 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21685533 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22686081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22686081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22686081 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22686081 — Safety Biomarker (SAF): IL-6 and IL-10
Study 28013381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28013381 — Surrogate Endpoint (SUR): Serum calcium
Study 31533605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31533605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31533605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29071928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24985376 — Surrogate Endpoint (SUR): Bone mineral density
Study 3535565 — Surrogate Endpoint (SUR): Blood pressure
Study 24184313 — Surrogate Endpoint (SUR): Bone mineral density
Study 18408387 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16485514 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10030287 — Surrogate Endpoint (SUR): Serum creatinine
Study 8719169 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2036244 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 20924392 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18250365 — Surrogate Endpoint (SUR): Blood pressure
Study 30169607 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30169607 — Predictive Biomarker (PRD): LTA4H mRNA
Genes: LTA4H; LTA4
Study 30169607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30169607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25183453 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 25183453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22021535 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17201073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17201073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9342580 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 9342580 — Surrogate Endpoint (SUR): Blood pressure
Study 27217455 — Predictive Biomarker (PRD): Hormone receptor
Study 30388905 — Surrogate Endpoint (SUR): Blood pressure
Study 28506387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28506387 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25559011 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 25559011 — Surrogate Endpoint (SUR): Blood pressure
Study 16144822 — Predictive Biomarker (PRD): RETN mRNA
Genes: RETN; FIZZ3; HXCP1; RSTN; UNQ407/PRO1199
Study 16144822 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 21787450 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 19488608 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15165944 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 23801867 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21795442 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 18198636 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18198636 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18198636 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7552649 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28002685 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 20634639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20634639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7705677 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16432463 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16596054 — Surrogate Endpoint (SUR): Bone mineral density
Study 1442643 — Surrogate Endpoint (SUR): Blood pressure
Study 31751012 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29576358 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 24918372 — Surrogate Endpoint (SUR): Blood pressure
Study 17689171 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 3314458 — Surrogate Endpoint (SUR): Blood pressure
Study 30697986 — Safety Biomarker (SAF): Th2 cell
Study 20368068 — Surrogate Endpoint (SUR): Blood pressure
Study 15807187 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15807187 — Surrogate Endpoint (SUR): Serum calcium
Study 15807187 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30337921 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21806617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16388329 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 12032877 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22827167 — Surrogate Endpoint (SUR): Blood pressure
Study 22827167 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17645387 — Surrogate Endpoint (SUR): Blood pressure
Study 11689736 — Surrogate Endpoint (SUR): Blood pressure
Study 30076156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22905971 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19634510 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 22174811 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22174811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17334239 — Surrogate Endpoint (SUR): Blood pressure
Study 11795352 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1928811 — Surrogate Endpoint (SUR): Blood pressure
Study 27305192 — Monitoring Biomarker (MOI): HBV DNA
Study 23288176 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 20234158 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 19284086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19284086 — Surrogate Endpoint (SUR): Blood pressure
Study 15818697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15818697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31655890 — Predictive Biomarker (PRD): CLCN1 mRNA
Genes: CLCN1; CLC1
Study 19923377 — Surrogate Endpoint (SUR): Blood pressure
Study 19923377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15871014 — Surrogate Endpoint (SUR): Urinary oxalate
Study 4010979 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 4010979 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16194199 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31594077 — Monitoring Biomarker (MOI): HBV DNA
Study 26427105 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22256738 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22256738 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 16890673 — Surrogate Endpoint (SUR): Bone mineral density
Study 3476732 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 22592092 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 12756407 — Surrogate Endpoint (SUR): Blood pressure
Study 29730659 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20854630 — Surrogate Endpoint (SUR): Blood pressure
Study 15057672 — Surrogate Endpoint (SUR): Blood pressure
Study 11434650 — Surrogate Endpoint (SUR): Blood pressure
Study 11434650 — Surrogate Endpoint (SUR): Serum creatinine
Study 31652688 — Surrogate Endpoint (SUR): Blood pressure
Study 17213752 — Surrogate Endpoint (SUR): Bone mineral density
Study 7923645 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2468874 — Surrogate Endpoint (SUR): Blood pressure
Study 30883517 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 30883517 — Predictive Biomarker (PRD): CD8A mRNA
Genes: CD8A; MAL
Study 30883517 — Predictive Biomarker (PRD): NCR1 mRNA
Genes: NCR1; LY94
Study 30883517 — Predictive Biomarker (PRD): TNFRSF4 mRNA
Genes: TNFRSF4; TXGP1L
Study 30883517 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 28258520 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 28258520 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 28258520 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 28258520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28258520 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 11052960 — Surrogate Endpoint (SUR): Blood pressure
Study 3936739 — Surrogate Endpoint (SUR): Blood pressure
Study 25986427 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25986427 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study 25986427 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25986427 — Surrogate Endpoint (SUR): Blood pressure
Study 15963202 — Surrogate Endpoint (SUR): Blood pressure
Study 11207870 — Surrogate Endpoint (SUR): Blood pressure
Study 28121706 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28121706 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26780276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28057652 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 25174865 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 18360014 — Surrogate Endpoint (SUR): Blood pressure
Study 26912438 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17075991 — Monitoring Biomarker (MOI): HBV DNA
Study 11342470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9412887 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3436104 — Surrogate Endpoint (SUR): Blood pressure
Study 25341548 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24347531 — Predictive Biomarker (PRD): HPN mRNA
Genes: HPN; TMPRSS1
Study 21905270 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19064988 — Predictive Biomarker (PRD): ESR1
Genes: NR3A1; Era; ER-alpha
Study 19064988 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19064988 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19064988 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12123209 — Surrogate Endpoint (SUR): Serum uric acid
Study 12123209 — Surrogate Endpoint (SUR): Serum potassium
Study 7778534 — Surrogate Endpoint (SUR): Blood pressure
Study 17319827 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 10710012 — Surrogate Endpoint (SUR): Blood pressure
Study 11322246 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6138058 — Surrogate Endpoint (SUR): Blood pressure
Study 17237316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8990684 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 1424620 — Surrogate Endpoint (SUR): Blood pressure
Study 20530107 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 17090953 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17090953 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9395805 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7957520 — Surrogate Endpoint (SUR): Blood pressure
Study 31230088 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 28554939 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17018656 — Surrogate Endpoint (SUR): Bone mineral density
Study 11166015 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30919997 — Surrogate Endpoint (SUR): Bone mineral density
Study 22980301 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 15802780 — Surrogate Endpoint (SUR): Bone mineral density
Study 2407875 — Surrogate Endpoint (SUR): Blood pressure
Study 3146197 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23604333 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 14668275 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 14668275 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31456498 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 21934055 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 26178508 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 26178508 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 26178508 — Predictive Biomarker (PRD): F9 mRNA
Genes: F9
Study 22669334 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15587828 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 2955804 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28736944 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26247037 — Safety Biomarker (SAF): MTHFR
Study 2090557 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28856940 — Surrogate Endpoint (SUR): Blood pressure
Study 9212969 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9212969 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9212969 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2447432 — Surrogate Endpoint (SUR): Blood pressure
Study 29952503 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20555294 — Predictive Biomarker (PRD): STK39 mRNA
Genes: STK39; SPAK
Study 15932522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12874489 — Surrogate Endpoint (SUR): Blood pressure
Study 29052245 — Predictive Biomarker (PRD): FAIM mRNA
Genes: FAIM; FAIM1
Study 22882843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22882843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20156339 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 20156339 — Surrogate Endpoint (SUR): Blood pressure
Study 8556396 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29483383 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29483383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20837887 — Surrogate Endpoint (SUR): Blood pressure
Study 16135590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28017524 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28017524 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 26780394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26780394 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26780394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26780394 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23171573 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23171573 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30660136 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30660136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30660136 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 30660136 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF