TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26857391 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 24612546 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24612546 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24612546 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 2681410 — Surrogate Endpoint (SUR): Blood pressure
Study 31860387 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 2956874 — Surrogate Endpoint (SUR): Blood pressure
Study 31396995 — Predictive Biomarker (PRD): PBK mRNA
Genes: PBK; TOPK
Study 15312348 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15312348 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11514693 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 9297994 — Surrogate Endpoint (SUR): Blood pressure
Study 30322408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26420761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26420761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3519243 — Surrogate Endpoint (SUR): Blood pressure
Study 24989702 — Surrogate Endpoint (SUR): Blood pressure
Study 22544010 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 8527263 — Surrogate Endpoint (SUR): Blood pressure
Study 15117982 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15117982 — Predictive Biomarker (PRD): Hormone receptor
Study 8198411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2898256 — Surrogate Endpoint (SUR): Blood pressure
Study 16404409 — Surrogate Endpoint (SUR): Blood pressure
Study 16404409 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8962903 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 6738373 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6738373 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21610154 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19596163 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 19596163 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19596163 — Surrogate Endpoint (SUR): Serum calcium
Study 19596163 — Surrogate Endpoint (SUR): Serum creatinine
Study 15767241 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10150325 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24158335 — Predictive Biomarker (PRD): SRY mRNA
Genes: SRY; TDF
Study 21130593 — Safety Biomarker (SAF): Protein AMBP
Genes: AMBP; HCP; ITIL
Study 21130593 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 25601966 — Safety Biomarker (SAF): CDA
Genes: CDD
Study 19922995 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16630454 — Surrogate Endpoint (SUR): Blood pressure
Study 14652125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8404438 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18441323 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18441323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30380038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3100145 — Surrogate Endpoint (SUR): Blood pressure
Study 3100145 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30732125 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25156125 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16940448 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15234826 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24621826 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 25010538 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 20133929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20133929 — Surrogate Endpoint (SUR): Blood pressure
Study 16344321 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15199622 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 15199622 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3948547 — Surrogate Endpoint (SUR): Serum potassium
Study 19203904 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30307614 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 12560305 — Surrogate Endpoint (SUR): Blood pressure
Study 28502609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25559299 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25559299 — Surrogate Endpoint (SUR): Blood pressure
Study 23807273 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14966943 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8134674 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9766410 — Surrogate Endpoint (SUR): Serum calcium
Study 3047526 — Surrogate Endpoint (SUR): Blood pressure
Study 23778768 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 26253728 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 18458892 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9590313 — Surrogate Endpoint (SUR): Blood pressure
Study 3392755 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 28095412 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28095412 — Surrogate Endpoint (SUR): Blood pressure
Study 15367188 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 15367188 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17339618 — Surrogate Endpoint (SUR): Bone mineral density
Study 9726242 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6815696 — Surrogate Endpoint (SUR): Blood pressure
Study 20386477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20386477 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20386477 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18757262 — Predictive Biomarker (PRD): Hormone receptor
Study 12571256 — Surrogate Endpoint (SUR): Serum creatinine
Study 10320237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10320237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10320237 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 10320237 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10320237 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30246715 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30246715 — Safety Biomarker (SAF): BDNF
Study 21234767 — Surrogate Endpoint (SUR): Blood pressure
Study 9354852 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 9354852 — Surrogate Endpoint (SUR): Blood pressure
Study 9000046 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9000046 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 26762368 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 24696417 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 24696417 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 21122199 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16164385 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10227567 — Surrogate Endpoint (SUR): Blood pressure
Study 10227567 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27100401 — Surrogate Endpoint (SUR): Blood pressure
Study 21965229 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 17094530 — Surrogate Endpoint (SUR): Blood pressure
Study 11321236 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11321236 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24992652 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23436915 — Surrogate Endpoint (SUR): Bone mineral density
Study 21753776 — Surrogate Endpoint (SUR): Blood pressure
Study 9221964 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 25008885 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20569928 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16351509 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 10196730 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31589645 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 31589645 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23858000 — Surrogate Endpoint (SUR): Blood pressure
Study 23858000 — Surrogate Endpoint (SUR): Serum sodium
Study 19795771 — Safety Biomarker (SAF): Hyaluronic acid
Study 11507005 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 6325044 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 6325044 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22157367 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16256861 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16256861 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22692651 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22692651 — Surrogate Endpoint (SUR): Blood pressure
Study 24821457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19207720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19207720 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17259403 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study 17259403 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 12082657 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12082657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8006395 — Monitoring Biomarker (MOI): HBV DNA
Study 19190211 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 16794504 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 9506009 — Surrogate Endpoint (SUR): Serum testosterone
Study 28577668 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26280823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26280823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26280823 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26280823 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23766338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20638827 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20638827 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30586750 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30586750 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27557300 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27557300 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24300595 — Surrogate Endpoint (SUR): Blood pressure
Study 3046889 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23730838 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23730838 — Predictive Biomarker (PRD): ISG15 mRNA
Genes: ISG15; G1P2; UCRP
Study 19942469 — Surrogate Endpoint (SUR): Bone mineral density
Study 19095129 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15888560 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10613617 — Surrogate Endpoint (SUR): Serum calcium
Study 10613617 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 10613617 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 7604798 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7604798 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29654893 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 9058493 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 3017401 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 15707563 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11239530 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 3051991 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3051991 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3051991 — Surrogate Endpoint (SUR): Blood pressure
Study 2908306 — Surrogate Endpoint (SUR): Blood pressure
Study 31974637 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 30299482 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 25933197 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21129866 — Surrogate Endpoint (SUR): Bone mineral density
Study 15308998 — Surrogate Endpoint (SUR): Blood pressure
Study 15308998 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9877264 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9877264 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9877264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9877264 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8066937 — Surrogate Endpoint (SUR): Blood pressure
Study 25520278 — Surrogate Endpoint (SUR): Blood pressure
Study 17122137 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17122137 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11736743 — Predictive Biomarker (PRD): BCAR1 mRNA
Genes: BCAR1; CAS; CASS1; CRKAS
Study 8095980 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6375703 — Surrogate Endpoint (SUR): Blood pressure
Study 29923299 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26685074 — Surrogate Endpoint (SUR): Serum creatinine
Study 20030435 — Safety Biomarker (SAF): Hyaluronic acid
Study 14654762 — Surrogate Endpoint (SUR): Blood pressure
Study 14654762 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 836153 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24368725 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24368725 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17885079 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 16584506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16584506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22133521 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22133521 — Safety Biomarker (SAF): BDNF
Study 18702965 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18702965 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6627695 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 30113395 — Surrogate Endpoint (SUR): Blood pressure
Study 20497186 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 11230779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11230779 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 7908610 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3171039 — Surrogate Endpoint (SUR): Blood pressure
Study 24409029 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 9266139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25802980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24670088 — Surrogate Endpoint (SUR): Serum calcium
Study 12070645 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 12070645 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12070645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 356598 — Surrogate Endpoint (SUR): Blood pressure
Study 30328153 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 19672253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15794388 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 15794388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 6255982 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29232436 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 21241793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15363816 — Surrogate Endpoint (SUR): Blood pressure
Study 11603173 — Surrogate Endpoint (SUR): Blood pressure
Study 2631971 — Surrogate Endpoint (SUR): Blood pressure
Study 16442368 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16442368 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16442368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11348664 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9686803 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25439558 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25439558 — Surrogate Endpoint (SUR): Blood pressure
Study 25439558 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19349322 — Surrogate Endpoint (SUR): Blood pressure
Study 16675238 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16675238 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31177714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31177714 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10637238 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 10637238 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29215955 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24131637 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 23006660 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 30068766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30068766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23130818 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16313111 — Predictive Biomarker (PRD): GAPDH mRNA
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 16313111 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 10487973 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28713004 — Predictive Biomarker (PRD): NGB mRNA
Genes: NGB
Study 17544861 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17544861 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 15385375 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 11475845 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 11475845 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11475845 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10149758 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 19271025 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 11095261 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 8797612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29648580 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 17530947 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 7692146 — Surrogate Endpoint (SUR): Blood pressure
Study 23025511 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 19142771 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 3149400 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3149400 — Safety Biomarker (SAF): Thyroid stimulating hormone