TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17139244 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31859211 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 24057294 — Surrogate Endpoint (SUR): Bone mineral density
Study 21765448 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study 19647670 — Surrogate Endpoint (SUR): Bone mineral density
Study 14612206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14612206 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 25295834 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 15228505 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 29106814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29106814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 707334 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30841823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21119150 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 18805249 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17079573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12941710 — Surrogate Endpoint (SUR): Blood pressure
Study 8742095 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 1418054 — Surrogate Endpoint (SUR): Blood pressure
Study 27490922 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 27490922 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27490922 — Surrogate Endpoint (SUR): Blood pressure
Study 7300705 — Surrogate Endpoint (SUR): Blood pressure
Study 30343264 — Surrogate Endpoint (SUR): Blood pressure
Study 28219190 — Monitoring Biomarker (MOI): Procalcitonin
Study 25597563 — Surrogate Endpoint (SUR): Blood pressure
Study 30672218 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22676245 — Predictive Biomarker (PRD): Hormone receptor
Study 20100026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20100026 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 2524387 — Surrogate Endpoint (SUR): Blood pressure
Study 31619483 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21646062 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 16434666 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 15117853 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 31486133 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17158426 — Predictive Biomarker (PRD): ACSM3 mRNA
Genes: ACSM3; SAH
Study 9228508 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26183139 — Surrogate Endpoint (SUR): Bone mineral density
Study 2744186 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 2744186 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 2744186 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 22574588 — Monitoring Biomarker (MOI): HBV DNA
Study 17082463 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23485078 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17470689 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29375198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30286483 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28753100 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 8110432 — Surrogate Endpoint (SUR): Blood pressure
Study 19798460 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19798460 — Surrogate Endpoint (SUR): Bone mineral density
Study 19798460 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16177941 — Surrogate Endpoint (SUR): Blood pressure
Study 30873676 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 30873676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30873676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26731191 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22431960 — Surrogate Endpoint (SUR): Serum creatinine
Study 2501817 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2501817 — Surrogate Endpoint (SUR): Blood pressure
Study 30973493 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 23936348 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23936348 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 23936348 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 23936348 — Predictive Biomarker (PRD): MAP2 mRNA
Genes: MAP2
Study 15471552 — Surrogate Endpoint (SUR): Blood pressure
Study 11287371 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11287371 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11287371 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9100581 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 3390394 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28297813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26395094 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 23393157 — Predictive Biomarker (PRD): NLGN2 mRNA
Genes: NLGN2; KIAA1366
Study 23393157 — Predictive Biomarker (PRD): NLGN4X mRNA
Genes: NLGN4X; KIAA1260; NLGN4; UNQ365/PRO701
Study 23393157 — Predictive Biomarker (PRD): NRXN1 mRNA
Genes: NRXN1
Study 23393157 — Predictive Biomarker (PRD): NRXN2 mRNA
Genes: NRXN2
Study 23393157 — Predictive Biomarker (PRD): NRXN3 mRNA
Genes: NRXN3; KIAA0743
Study 23393157 — Predictive Biomarker (PRD): ARHGEF9 mRNA
Genes: ARHGEF9; ARHDH9; KIAA0424
Study 22014698 — Predictive Biomarker (PRD): SLMAP mRNA
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 16329138 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12793617 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 30170853 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20395358 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10624765 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2167951 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 27959607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27959607 — Safety Biomarker (SAF): Interleukin 12
Study 19279975 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19279975 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 15890545 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 2209240 — Monitoring Biomarker (MOI): HBV DNA
Study 24004237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19477397 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 2067506 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2067506 — Surrogate Endpoint (SUR): Blood pressure
Study 6193349 — Surrogate Endpoint (SUR): Blood pressure
Study 20813872 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 30664020 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 27062800 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 8011000 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 376236 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 28824041 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21343556 — Surrogate Endpoint (SUR): Serum creatinine
Study 9176034 — Surrogate Endpoint (SUR): Blood pressure
Study 1376842 — Surrogate Endpoint (SUR): Blood pressure
Study 29743380 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29743380 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25113414 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25113414 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 20492655 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20492655 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19167588 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19167588 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15278749 — Surrogate Endpoint (SUR): Bone mineral density
Study 7863047 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25073921 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): VGF mRNA
Genes: VGF
Study 22442773 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 17511155 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15625210 — Surrogate Endpoint (SUR): Blood pressure
Study 10357349 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10357349 — Surrogate Endpoint (SUR): Blood pressure
Study 31762338 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25885095 — Surrogate Endpoint (SUR): Blood pressure
Study 7562888 — Surrogate Endpoint (SUR): Blood pressure
Study 17175037 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9287241 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18728266 — Surrogate Endpoint (SUR): Blood pressure
Study 18728266 — Surrogate Endpoint (SUR): Serum uric acid
Study 6435703 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 28386694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27862178 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27862178 — Monitoring Biomarker (MOI): HBV DNA
Study 1430286 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11036470 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20210615 — Surrogate Endpoint (SUR): Blood pressure
Study 18329126 — Monitoring Biomarker (MOI): HBV DNA
Study 15949731 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19158197 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9395005 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8179173 — Surrogate Endpoint (SUR): Blood pressure
Study 28959911 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 28959911 — Predictive Biomarker (PRD): FAU mRNA
Genes: FAU
Study 16532017 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 10749297 — Predictive Biomarker (PRD): PTRH1 mRNA
Genes: PTRH1; C9orf115
Study 29490101 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 28628702 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30543598 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30543598 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16133961 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 11864514 — Surrogate Endpoint (SUR): Bone mineral density
Study 7805900 — Surrogate Endpoint (SUR): Sperm parameters
Study 1952472 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1952472 — Surrogate Endpoint (SUR): Blood pressure
Study 1952472 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31770287 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 31770287 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19847078 — Surrogate Endpoint (SUR): Serum sodium
Study 20107198 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18046669 — Surrogate Endpoint (SUR): Serum calcium
Study 2208013 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21606537 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21606537 — Surrogate Endpoint (SUR): Bone mineral density
Study 19117121 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16076380 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 10072008 — Surrogate Endpoint (SUR): Blood pressure
Study 23729801 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19398651 — Surrogate Endpoint (SUR): Blood pressure
Study 10088066 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15465986 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 11145479 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11145479 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7989902 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17563401 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17563401 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 16274919 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 7729640 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2188772 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2188772 — Surrogate Endpoint (SUR): Blood pressure
Study 6771173 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 6771173 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30560679 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16060911 — Predictive Biomarker (PRD): SSTR1 mRNA
Genes: SSTR1
Study 16060911 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study 14607681 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29166140 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29166140 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26494833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24346757 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 20631210 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 18167173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18167173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18167173 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18167173 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10982347 — Predictive Biomarker (PRD): EIF2AK2 mRNA
Genes: EIF2AK2; PKR; PRKR
Study 1462021 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1462021 — Surrogate Endpoint (SUR): Blood pressure
Study 28617537 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28617537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22676856 — Surrogate Endpoint (SUR): Blood pressure
Study 23649042 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18268858 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 11790928 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10216073 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10216073 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8682055 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8682055 — Surrogate Endpoint (SUR): Serum potassium
Study 8682055 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2184556 — Surrogate Endpoint (SUR): Blood pressure
Study 31688650 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 29034644 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 22269963 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 9422299 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30367991 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 30367991 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31929371 — Safety Biomarker (SAF): MTHFR
Study 31929371 — Surrogate Endpoint (SUR): Serum creatinine
Study 31929371 — Surrogate Endpoint (SUR): Blood pressure
Study 18981464 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17125606 — Monitoring Biomarker (MOI): HBV DNA
Study 10589000 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30964435 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 23994882 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23994882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22314980 — Surrogate Endpoint (SUR): Blood pressure
Study 14769678 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 14769678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2953865 — Predictive Biomarker (PRD): C9 mRNA
Genes: C9
Study 10165114 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27258294 — Surrogate Endpoint (SUR): Blood pressure
Study 24943285 — Surrogate Endpoint (SUR): Blood pressure
Study 22564271 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 20629812 — Surrogate Endpoint (SUR): Blood pressure
Study 12020302 — Surrogate Endpoint (SUR): Bone mineral density
Study 9792383 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2541397 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 1958436 — Surrogate Endpoint (SUR): Blood pressure
Study 616212 — Surrogate Endpoint (SUR): Blood pressure
Study 17803344 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17803344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8959154 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 26644241 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 26644241 — Surrogate Endpoint (SUR): Blood pressure
Study 1952269 — Surrogate Endpoint (SUR): Blood pressure
Study 18286351 — Surrogate Endpoint (SUR): Serum creatinine
Study 17132537 — Surrogate Endpoint (SUR): Blood pressure
Study 14529881 — Surrogate Endpoint (SUR): Serum creatinine
Study 1532534 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1532534 — Surrogate Endpoint (SUR): Blood pressure
Study 1532534 — Surrogate Endpoint (SUR): Serum creatinine
Study 3921597 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30293878 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30390684 — Predictive Biomarker (PRD): CRHR1 mRNA
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 30390684 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 30390684 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 20932411 — Predictive Biomarker (PRD): Hormone receptor
Study 12386644 — Surrogate Endpoint (SUR): Blood pressure
Study 7748969 — Surrogate Endpoint (SUR): Serum creatinine
Study 30033879 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 17451796 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7542473 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30602032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30602032 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26430694 — Surrogate Endpoint (SUR): Blood pressure
Study 3132868 — Surrogate Endpoint (SUR): Blood pressure
Study 3089490 — Surrogate Endpoint (SUR): Blood pressure
Study 29330911 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 26820653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26820653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26820653 — Safety Biomarker (SAF): IL-6 and IL-10
Study 25547247 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25547247 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22459636 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 17135854 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25453395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25453395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23218100 — Surrogate Endpoint (SUR): Blood pressure
Study 23218100 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23218100 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21949049 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 21949049 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11704601 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 21794899 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 9377855 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7794289 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20721516 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3140687 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 3140687 — Surrogate Endpoint (SUR): Blood pressure
Study 30999110 — Safety Biomarker (SAF): Derived neutrophil to lymphocyte
Study 30999110 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 30999110 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25432415 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25432415 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17017486 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30353590 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30353590 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15937294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2