TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11501455 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 2691478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27684308 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22263674 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22263674 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22263674 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22263674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22166525 — Predictive Biomarker (PRD): GLI2 mRNA
Genes: GLI2; THP
Study 17635177 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1951336 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28974849 — Surrogate Endpoint (SUR): Blood pressure
Study 21955403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21955403 — Surrogate Endpoint (SUR): Blood pressure
Study 8457237 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8457237 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 31372210 — Surrogate Endpoint (SUR): Bacterial count
Study 10381531 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 7721419 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 7721419 — Surrogate Endpoint (SUR): Blood pressure
Study 7721419 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10145317 — Predictive Biomarker (PRD): TTL mRNA
Genes: TTL
Study 11985186 — Surrogate Endpoint (SUR): Blood pressure
Study 776441 — Surrogate Endpoint (SUR): Blood pressure
Study 23731768 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21411606 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 19268410 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9477980 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16473984 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 10692524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10692524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9179687 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1422972 — Surrogate Endpoint (SUR): Bone mineral density
Study 1422972 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 1422972 — Surrogate Endpoint (SUR): Serum calcium
Study 24607301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24607301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24607301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24607301 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22952756 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2514430 — Surrogate Endpoint (SUR): Blood pressure
Study 25472509 — Surrogate Endpoint (SUR): Blood pressure
Study 23750422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23750422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23750422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19261138 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30833435 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 14694036 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 14694036 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 27232052 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27232052 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 20189517 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 18180641 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6152739 — Surrogate Endpoint (SUR): Blood pressure
Study 24383505 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27129892 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 25330671 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18824643 — Surrogate Endpoint (SUR): Serum potassium
Study 18824643 — Surrogate Endpoint (SUR): Serum creatinine
Study 10597783 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8521562 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1958433 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 17325296 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17325296 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11788172 — Surrogate Endpoint (SUR): Blood pressure
Study 7979426 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 26405092 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26405092 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26405092 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23138388 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 17192538 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17192538 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22520119 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17010979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7639806 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12476475 — Surrogate Endpoint (SUR): Blood pressure
Study 22122202 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12153608 — Surrogate Endpoint (SUR): Bone mineral density
Study 16799399 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 8355124 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 8355124 — Surrogate Endpoint (SUR): Bone mineral density
Study 31397179 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 27858072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27858072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23672570 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14629771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10735900 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30423575 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12516106 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20129825 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10150537 — Surrogate Endpoint (SUR): Blood pressure
Study 27315546 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20549829 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20549829 — Predictive Biomarker (PRD): Hormone receptor
Study 20549829 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16155261 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 1334821 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30277921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15983301 — Surrogate Endpoint (SUR): Blood pressure
Study 10877192 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 6869204 — Surrogate Endpoint (SUR): Blood pressure
Study 6869204 — Surrogate Endpoint (SUR): Serum potassium
Study 22972862 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20583949 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12527674 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 8898763 — Surrogate Endpoint (SUR): Blood pressure
Study 6325994 — Surrogate Endpoint (SUR): Blood pressure
Study 30476104 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30476104 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 30476104 — Predictive Biomarker (PRD): CYB5A mRNA
Genes: CYB5A; CYB5
Study 30476104 — Predictive Biomarker (PRD): FURIN mRNA
Genes: FURIN; FUR; PACE; PCSK3
Study 30476104 — Predictive Biomarker (PRD): GPX4 mRNA
Genes: GPX4
Study 30476104 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30476104 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 30476104 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30476104 — Predictive Biomarker (PRD): PCSK2 mRNA
Genes: PCSK2; NEC2
Study 22840353 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19792989 — Surrogate Endpoint (SUR): Serum potassium
Study 17719559 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11345374 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 21613310 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21613310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16958291 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 15193480 — Surrogate Endpoint (SUR): Sperm parameters
Study 9373765 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30833486 — Predictive Biomarker (PRD): Hormone receptor
Study 20662716 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20662716 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12172314 — Surrogate Endpoint (SUR): Blood pressure
Study 7605708 — Surrogate Endpoint (SUR): Bone mineral density
Study 31577041 — Safety Biomarker (SAF): Hyaluronic acid
Study 19683429 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19317165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19317165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1879030 — Surrogate Endpoint (SUR): Blood pressure
Study 26503370 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 23317171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8110564 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8110564 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28784453 — Surrogate Endpoint (SUR): Blood pressure
Study 11186221 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11186221 — Surrogate Endpoint (SUR): Blood pressure
Study 28329315 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 28329315 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 20924095 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12409965 — Surrogate Endpoint (SUR): Blood pressure
Study 12409965 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12409965 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16796078 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16796078 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16796078 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11259986 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3103158 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19473822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19473822 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19473822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7272178 — Surrogate Endpoint (SUR): Blood pressure
Study 31036468 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31036468 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31036468 — Predictive Biomarker (PRD): Hormone receptor
Study 21884007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19538242 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10598600 — Surrogate Endpoint (SUR): Blood pressure
Study 30776016 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 25180876 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 22056021 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21123578 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 17613279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17613279 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12005153 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 26162521 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15502721 — Surrogate Endpoint (SUR): Blood pressure
Study 15502721 — Surrogate Endpoint (SUR): Serum creatinine
Study 11684376 — Surrogate Endpoint (SUR): Blood pressure
Study 7888289 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3285878 — Surrogate Endpoint (SUR): Blood pressure
Study 28537581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28537581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25380149 — Surrogate Endpoint (SUR): Blood pressure
Study 20197560 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 12732395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12732395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12732395 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12732395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10372217 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10372217 — Surrogate Endpoint (SUR): Blood pressure
Study 9082342 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27348904 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17950182 — Surrogate Endpoint (SUR): Blood pressure
Study 20389106 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 2059758 — Predictive Biomarker (PRD): CD6 mRNA
Genes: CD6
Study 6851564 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 28229275 — Safety Biomarker (SAF): Hyaluronic acid
Study 20962623 — Surrogate Endpoint (SUR): Serum creatinine
Study 20962623 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22695185 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22695185 — Safety Biomarker (SAF): BDNF
Study 11726264 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11421505 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15177518 — Surrogate Endpoint (SUR): Blood pressure
Study 30974993 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 25201887 — Surrogate Endpoint (SUR): Blood pressure
Study 17062648 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 10493673 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 8757423 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19589010 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19589010 — Safety Biomarker (SAF): Urinary microalbumin
Study 7713273 — Surrogate Endpoint (SUR): Blood pressure
Study 28902127 — Predictive Biomarker (PRD): MZB1 mRNA
Genes: MZB1; MEDA7; PACAP; HSPC190
Study 23708326 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23708326 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9041098 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9041098 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30431378 — Surrogate Endpoint (SUR): Blood pressure
Study 9238624 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9238624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11253316 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 11281052 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19548439 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 19548439 — Predictive Biomarker (PRD): TIMM8A mRNA
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 19548439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19548439 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31303147 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31303147 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 31303147 — Surrogate Endpoint (SUR): Bone mineral density
Study 26756114 — Surrogate Endpoint (SUR): Bone mineral density
Study 26756114 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15848577 — Surrogate Endpoint (SUR): Serum creatinine
Study 7597378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28847152 — Surrogate Endpoint (SUR): Serum creatinine
Study 23890317 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11915777 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7908501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31647139 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 29232314 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 20584129 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 27560676 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19875309 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15642550 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15642550 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19283791 — Surrogate Endpoint (SUR): Bone mineral density
Study 17616536 — Surrogate Endpoint (SUR): Serum potassium
Study 17616536 — Surrogate Endpoint (SUR): Blood pressure
Study 15775731 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30219249 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30219249 — Surrogate Endpoint (SUR): Blood pressure
Study 3591604 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21118366 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 10793878 — Surrogate Endpoint (SUR): Bone mineral density
Study 9387527 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27287856 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12571693 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23348933 — Surrogate Endpoint (SUR): Blood pressure
Study 7640328 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31809601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28234053 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 25980351 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 23963546 — Surrogate Endpoint (SUR): Blood pressure
Study 17877953 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15753494 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2548548 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2548548 — Surrogate Endpoint (SUR): Blood pressure
Study 27410480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27410480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8562975 — Safety Biomarker (SAF): Interleukin 1
Study 8562975 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8562975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8562975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17955229 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 17955229 — Surrogate Endpoint (SUR): Blood pressure
Study 8701878 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6636913 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27734232 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17954173 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 17954173 — Surrogate Endpoint (SUR): Serum creatinine
Study 11825344 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11825344 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol