TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31295270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26426352 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 26426352 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 16466172 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 12833109 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12833109 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1998314 — Monitoring Biomarker (MOI): HBV DNA
Study 20634742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31000233 — Predictive Biomarker (PRD): GDA mRNA
Genes: GDA; KIAA1258
Study 7715258 — Surrogate Endpoint (SUR): Blood pressure
Study 2516609 — Surrogate Endpoint (SUR): Blood pressure
Study 28124585 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 16780258 — Surrogate Endpoint (SUR): Blood pressure
Study 15515752 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 2022477 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22838957 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 22838957 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 2688071 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 31594690 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31594690 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 30537153 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 30537153 — Surrogate Endpoint (SUR): Blood pressure
Study 28456108 — Surrogate Endpoint (SUR): Blood pressure
Study 22706585 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19935143 — Surrogate Endpoint (SUR): Blood pressure
Study 15763433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15763433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11452241 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 30919036 — Predictive Biomarker (PRD): RGS2 mRNA
Genes: RGS2; G0S8; GIG31
Study 30919036 — Safety Biomarker (SAF): Reactive oxygen species
Study 29546297 — Surrogate Endpoint (SUR): Blood pressure
Study 29546297 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 24651746 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 30507875 — Surrogate Endpoint (SUR): Bone mineral density
Study 25415807 — Surrogate Endpoint (SUR): Serum potassium
Study 14707470 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 14707470 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 6394890 — Surrogate Endpoint (SUR): Blood pressure
Study 26001339 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25034652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25034652 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12409326 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 2020274 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 2020274 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16842977 — Surrogate Endpoint (SUR): Blood pressure
Study 14998561 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 14998561 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30499511 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30499511 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 20151772 — Surrogate Endpoint (SUR): Blood pressure
Study 9172968 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31096121 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 26194270 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8703460 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23336248 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 21315203 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16987384 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8381800 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 26631000 — Surrogate Endpoint (SUR): Blood pressure
Study 9106558 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 25483416 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 28680858 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 22152833 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 12576412 — Surrogate Endpoint (SUR): Blood pressure
Study 11910049 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2044652 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 31353759 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 26976426 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 26976426 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26976426 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 26976426 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26976426 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18760765 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 10814631 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21739259 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 21739259 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21739259 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20950883 — Surrogate Endpoint (SUR): Blood pressure
Study 17659159 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17659159 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23022464 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21807321 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21807321 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21807321 — Surrogate Endpoint (SUR): Serum creatinine
Study 21807321 — Surrogate Endpoint (SUR): Blood pressure
Study 12745612 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11081892 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 11081892 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 3159163 — Surrogate Endpoint (SUR): Blood pressure
Study 20498393 — Predictive Biomarker (PRD): Microsatellite instability
Study 18356346 — Surrogate Endpoint (SUR): Blood pressure
Study 11228380 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30441880 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 30441880 — Surrogate Endpoint (SUR): Blood pressure
Study 10634839 — Surrogate Endpoint (SUR): Blood pressure
Study 30208394 — Surrogate Endpoint (SUR): Blood pressure
Study 24889399 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 11903856 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 9477010 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9477010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19945857 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19945857 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12545147 — Surrogate Endpoint (SUR): Serum calcium
Study 10535881 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 7974899 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 28770947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20689465 — Surrogate Endpoint (SUR): Bone mineral density
Study 2479187 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28762527 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 28762527 — Surrogate Endpoint (SUR): Bone mineral density
Study 8222651 — Surrogate Endpoint (SUR): Blood pressure
Study 26591200 — Surrogate Endpoint (SUR): Blood pressure
Study 21627558 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 12679710 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9457388 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15877992 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29630134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29630134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24256699 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1489073 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 1489073 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17653859 — Predictive Biomarker (PRD): Hormone receptor
Study 10729389 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 10729389 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10729389 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28801122 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 28801122 — Surrogate Endpoint (SUR): Bone mineral density
Study 28801122 — Surrogate Endpoint (SUR): Serum calcium
Study 28801122 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20705902 — Surrogate Endpoint (SUR): Blood pressure
Study 17403578 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20705534 — Surrogate Endpoint (SUR): Blood pressure
Study 10567626 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 30352291 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27612281 — Predictive Biomarker (PRD): PTH1R mRNA
Genes: PTH1R; PTHR; PTHR1
Study 27612281 — Surrogate Endpoint (SUR): Bone mineral density
Study 27612281 — Surrogate Endpoint (SUR): New morphometric vertebral fractures
Study 26257021 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19397693 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19397693 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19397693 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15114043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28898104 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 26399868 — Surrogate Endpoint (SUR): Blood pressure
Study 24617124 — Surrogate Endpoint (SUR): Blood pressure
Study 25605283 — Surrogate Endpoint (SUR): Sputum culture conversion to negative
Study 9345375 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 6297363 — Surrogate Endpoint (SUR): Blood pressure
Study 21785107 — Surrogate Endpoint (SUR): Blood pressure
Study 9397322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2124925 — Surrogate Endpoint (SUR): Blood pressure
Study 30221400 — Predictive Biomarker (PRD): OLFM4 mRNA
Genes: OLFM4; GW112; UNQ362/PRO698
Study 28241356 — Surrogate Endpoint (SUR): Serum testosterone
Study 24281841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22157845 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20231228 — Surrogate Endpoint (SUR): Blood pressure
Study 17664059 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17664059 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16297753 — Surrogate Endpoint (SUR): Blood pressure
Study 6122098 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17608790 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 17608790 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8076564 — Surrogate Endpoint (SUR): Blood pressure
Study 9013264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3877283 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 27391818 — Surrogate Endpoint (SUR): Blood pressure
Study 17637782 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 15699445 — Surrogate Endpoint (SUR): Blood pressure
Study 19726310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19726310 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 15496643 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17987059 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 17987059 — Safety Biomarker (SAF): BDNF
Study 11454106 — Surrogate Endpoint (SUR): Blood pressure
Study 31352829 — Surrogate Endpoint (SUR): Blood pressure
Study 25640526 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 18028460 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12716519 — Monitoring Biomarker (MOI): HBV DNA
Study 15705013 — Surrogate Endpoint (SUR): Blood pressure
Study 12546641 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12546641 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12546641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10844830 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8872838 — Surrogate Endpoint (SUR): Blood pressure
Study 29804469 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 19766403 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9346384 — Surrogate Endpoint (SUR): Serum creatinine
Study 9346384 — Surrogate Endpoint (SUR): Blood pressure
Study 9346384 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28891228 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 15959784 — Safety Biomarker (SAF): Hyaluronic acid
Study 29203153 — Surrogate Endpoint (SUR): Blood pressure
Study 22075751 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22075751 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12897561 — Surrogate Endpoint (SUR): Blood pressure
Study 10581665 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8721800 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8721800 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14613759 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14613759 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14613759 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8602586 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8602586 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30616912 — Predictive Biomarker (PRD): IKBKG mRNA
Genes: IKBKG; FIP3; NEMO
Study 21329501 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 17286150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17286150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11118395 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 9701523 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 26059225 — Surrogate Endpoint (SUR): Serum potassium
Study 24228710 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 24228710 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21624699 — Safety Biomarker (SAF): Hyaluronic acid
Study 18774180 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22246377 — Surrogate Endpoint (SUR): Blood pressure
Study 20436265 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 20436265 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 27598855 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 23659362 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 17545881 — Surrogate Endpoint (SUR): Blood pressure
Study 30672619 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23154591 — Surrogate Endpoint (SUR): Serum creatinine
Study 23154591 — Surrogate Endpoint (SUR): Blood pressure
Study 21252014 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21252014 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11125686 — Surrogate Endpoint (SUR): Blood pressure
Study 9235523 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9235523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19841160 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19841160 — Surrogate Endpoint (SUR): Blood pressure
Study 19841160 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19841160 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19841160 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18764914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18764914 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 14646710 — Surrogate Endpoint (SUR): Bone mineral density
Study 28116649 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28116649 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24956970 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24956970 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19380868 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19380868 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study 2700773 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 166929 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 24720526 — Surrogate Endpoint (SUR): Blood pressure
Study 24720526 — Surrogate Endpoint (SUR): Bone mineral density
Study 9290118 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 8365385 — Surrogate Endpoint (SUR): Blood pressure
Study 3602015 — Surrogate Endpoint (SUR): Blood pressure
Study 25462913 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 10349922 — Surrogate Endpoint (SUR): Blood pressure
Study 12595492 — Surrogate Endpoint (SUR): Serum calcium
Study 11042235 — Surrogate Endpoint (SUR): Blood pressure
Study 30606259 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29445928 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26334249 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 23069270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23069270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20497416 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20497416 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 29105521 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25147328 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12587107 — Surrogate Endpoint (SUR): Serum calcium
Study 2471025 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 169536 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31871140 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 10757556 — Surrogate Endpoint (SUR): Serum creatinine
Study 11940375 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 11940375 — Surrogate Endpoint (SUR): Bone mineral density
Study 11107582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8571309 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8571309 — Predictive Biomarker (PRD): PPIC mRNA
Genes: PPIC; CYPC
Study 8571309 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1748139 — Surrogate Endpoint (SUR): Blood pressure
Study 6760679 — Surrogate Endpoint (SUR): Blood pressure
Study 30923313 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 12042891 — Surrogate Endpoint (SUR): Blood pressure
Study 22106341 — Surrogate Endpoint (SUR): Bone mineral density
Study 19843623 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 12117445 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 8568293 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29893313 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 27454135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27454135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31240711 — Surrogate Endpoint (SUR): Blood pressure
Study 28321566 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 19148110 — Predictive Biomarker (PRD): TNFA
Genes: TNF; TNFSF2; DIF; TNF-alpha
Study 19148110 — Surrogate Endpoint (SUR): Blood pressure
Study 3525055 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 3525055 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26631904 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27543500 — Surrogate Endpoint (SUR): Blood pressure
Study 27543500 — Surrogate Endpoint (SUR): Serum calcium