TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15265408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15265408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15265408 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15265408 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 15265408 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16336763 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28829051 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 31442298 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 31442298 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21982669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21982669 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8621132 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29961998 — Surrogate Endpoint (SUR): Blood pressure
Study 24257390 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3062906 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 22459275 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 8677869 — Surrogate Endpoint (SUR): Blood pressure
Study 31576697 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30032978 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15787663 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10844383 — Surrogate Endpoint (SUR): Serum creatinine
Study 10844383 — Surrogate Endpoint (SUR): Blood pressure
Study 9850354 — Surrogate Endpoint (SUR): Bone mineral density
Study 9850354 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29684999 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29684999 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 29684999 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19026808 — Surrogate Endpoint (SUR): Blood pressure
Study 12813334 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30862680 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 29894287 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 29894287 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 27688236 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25157768 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18853833 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19304555 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 17586130 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29858625 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29858625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29858625 — Surrogate Endpoint (SUR): Blood pressure
Study 29858625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28807576 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 8265877 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2949057 — Surrogate Endpoint (SUR): Blood pressure
Study 16504579 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 10024335 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10024335 — Surrogate Endpoint (SUR): Blood pressure
Study 6162599 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 27390976 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 23133602 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 9853770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9853770 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7733478 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 18981325 — Surrogate Endpoint (SUR): Blood pressure
Study 31675189 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 27379965 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27379965 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 27379965 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19650753 — Surrogate Endpoint (SUR): Serum potassium
Study 19650753 — Surrogate Endpoint (SUR): Blood pressure
Study 28929577 — Surrogate Endpoint (SUR): Blood pressure
Study 11225999 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31265730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18569914 — Surrogate Endpoint (SUR): Serum calcium
Study 11909785 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11909785 — Surrogate Endpoint (SUR): Blood pressure
Study 7503066 — Surrogate Endpoint (SUR): Blood pressure
Study 25456838 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22448480 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8104656 — Predictive Biomarker (PRD): ASPRV1 mRNA
Genes: ASPRV1; SASP
Study 8104656 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30289950 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 30289950 — Predictive Biomarker (PRD): SCARB1 mRNA
Genes: SCARB1; CD36L1; CLA1
Study 25325204 — Surrogate Endpoint (SUR): Serum calcium
Study 22543771 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 20615885 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18415679 — Monitoring Biomarker (MOI): Procalcitonin
Study 18415679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10813378 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8858355 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 30060707 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22311004 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 22311004 — Surrogate Endpoint (SUR): Blood pressure
Study 1952037 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21505984 — Surrogate Endpoint (SUR): Serum creatinine
Study 21505984 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19409038 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19409038 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19409038 — Predictive Biomarker (PRD); Safety Biomarker (SAF): EGFR
Genes: ERBB1; ERRP
Study 19409038 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18546895 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10433097 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23596781 — Predictive Biomarker (PRD): TMPRSS13 mRNA
Genes: TMPRSS13; MSP; TMPRSS11
Study 23280675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 21593301 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 28108224 — Surrogate Endpoint (SUR): Bone mineral density
Study 26054049 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26054049 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15126541 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15126541 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15126541 — Surrogate Endpoint (SUR): Blood pressure
Study 11422471 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 29906071 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29906071 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18928091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18928091 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18928091 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18928091 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28700482 — Surrogate Endpoint (SUR): Serum creatinine
Study 21714999 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15541202 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 30725537 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30725537 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18595519 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22472546 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8598838 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26138593 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11518061 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 8181115 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29319408 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 19064533 — Surrogate Endpoint (SUR): Blood pressure
Study 7030372 — Surrogate Endpoint (SUR): Blood pressure
Study 9289703 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 9289703 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27627109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27627109 — Predictive Biomarker (PRD): PLIN1 mRNA
Genes: PLIN1; PERI; PLIN
Study 27627109 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 27627109 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 27627109 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20545703 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10325264 — Predictive Biomarker (PRD): FMR1
Genes: FMRP; FRAXA; MGC87458
Study 2031913 — Predictive Biomarker (PRD): NID1 mRNA
Genes: NID1; NID
Study 29750900 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 23013369 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20171653 — Predictive Biomarker (PRD): RNASE2 mRNA
Genes: RNASE2; EDN; RNS2
Study 9218198 — Surrogate Endpoint (SUR): Blood pressure
Study 31498799 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 24956971 — Surrogate Endpoint (SUR): Blood pressure
Study 23276189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23276189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8018455 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8018455 — Surrogate Endpoint (SUR): Blood pressure
Study 20882268 — Surrogate Endpoint (SUR): Serum potassium
Study 20882268 — Surrogate Endpoint (SUR): Serum creatinine
Study 19243424 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 9824573 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 31706052 — Surrogate Endpoint (SUR): Bone mineral density
Study 21836511 — Surrogate Endpoint (SUR): Serum creatinine
Study 19680260 — Surrogate Endpoint (SUR): Blood pressure
Study 17554712 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23970363 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18847416 — Surrogate Endpoint (SUR): Blood pressure
Study 16314018 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 3904899 — Surrogate Endpoint (SUR): Blood pressure
Study 17980217 — Surrogate Endpoint (SUR): Blood pressure
Study 12006310 — Surrogate Endpoint (SUR): Blood pressure
Study 9653595 — Surrogate Endpoint (SUR): Blood pressure
Study 2480147 — Surrogate Endpoint (SUR): Blood pressure
Study 30446246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30446246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11113426 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24636395 — Surrogate Endpoint (SUR): Blood pressure
Study 23318611 — Surrogate Endpoint (SUR): Blood pressure
Study 20303352 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20303352 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18393052 — Surrogate Endpoint (SUR): Blood pressure
Study 1549632 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 2862882 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 27862904 — Surrogate Endpoint (SUR): Blood pressure
Study 25617858 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25617858 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22074711 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14676238 — Surrogate Endpoint (SUR): Blood pressure
Study 8396158 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19393999 — Safety Biomarker (SAF): Hyaluronic acid
Study 8583779 — Surrogate Endpoint (SUR): Blood pressure
Study 15168035 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15168035 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 389223 — Surrogate Endpoint (SUR): Blood pressure
Study 23297849 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 20571097 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20571097 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17449110 — Surrogate Endpoint (SUR): Blood pressure
Study 22945607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21367998 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 18604013 — Surrogate Endpoint (SUR): Blood pressure
Study 14712164 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9490600 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7817355 — Surrogate Endpoint (SUR): Blood pressure
Study 7817355 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29625762 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23726675 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 29588062 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23695648 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 23695648 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23695648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23695648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10453373 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 10453373 — Predictive Biomarker (PRD): MUC2 mRNA
Genes: MUC2; SMUC
Study 10453373 — Predictive Biomarker (PRD): MUC4 mRNA
Genes: MUC4
Study 10453373 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 10453373 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study 10453373 — Predictive Biomarker (PRD): MUC6 mRNA
Genes: MUC6
Study 2087856 — Surrogate Endpoint (SUR): Blood pressure
Study 30640654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16320926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29886470 — Surrogate Endpoint (SUR): Serum sodium
Study 29886470 — Surrogate Endpoint (SUR): Serum calcium
Study 15845879 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 29756595 — Surrogate Endpoint (SUR): Bone mineral density
Study 15831804 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28625282 — Surrogate Endpoint (SUR): Sperm parameters
Study 28625282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28625282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28625282 — Safety Biomarker (SAF): Reactive oxygen species
Study 28625282 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27484017 — Predictive Biomarker (PRD): ARHGEF5 mRNA
Genes: ARHGEF5; TIM
Study 18495456 — Safety Biomarker (SAF): MTHFR
Study 10084465 — Surrogate Endpoint (SUR): Serum potassium
Study 10084465 — Surrogate Endpoint (SUR): Blood pressure
Study 7737632 — Surrogate Endpoint (SUR): Serum alkaline phosphatase and bilirubin
Study 7737632 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31711605 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 18520275 — Surrogate Endpoint (SUR): Blood pressure
Study 1782726 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 1782726 — Surrogate Endpoint (SUR): Serum calcium
Study 7006285 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26493396 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26493396 — Surrogate Endpoint (SUR): Blood pressure
Study 24574190 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23006632 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29160925 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21169106 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 25920468 — Surrogate Endpoint (SUR): Blood pressure
Study 17695603 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 12017403 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7741372 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31508861 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 22120913 — Predictive Biomarker (PRD): Liver iron
Study 21194441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21194441 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 21194441 — Safety Biomarker (SAF): Interleukin 1
Study 12488789 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 9498410 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 2564723 — Surrogate Endpoint (SUR): Blood pressure
Study 2564723 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28058491 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 28058491 — Predictive Biomarker (PRD): OLIG2 mRNA
Genes: OLIG2; BHLHB1; BHLHE19; PRKCBP2; RACK17
Study 28058491 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28058491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 14743961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14743961 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27440671 — Predictive Biomarker (PRD): RUNX2 mRNA
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 27440671 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 22008715 — Predictive Biomarker (PRD): SLA mRNA
Genes: SLA; SLAP; SLAP1
Study 29498347 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 29498347 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 29498347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24362951 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24362951 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24362951 — Predictive Biomarker (PRD): Hormone receptor
Study 22863207 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12356611 — Monitoring Biomarker (MOI): HBV DNA
Study 26387973 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 241599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30715779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23169695 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 19166395 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 15233550 — Surrogate Endpoint (SUR): Bone mineral density
Study 27282457 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 12907822 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 10976988 — Surrogate Endpoint (SUR): Bone mineral density
Study 1506543 — Surrogate Endpoint (SUR): Blood pressure
Study 11922851 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 2148882 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30563932 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 27654012 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 27654012 — Safety Biomarker (SAF): Hyaluronic acid
Study 22205554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10872186 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9166391 — Surrogate Endpoint (SUR): Bone mineral density
Study 23865441 — Surrogate Endpoint (SUR): Blood pressure
Study 10890543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16508385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2