TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18672194 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 12742805 — Surrogate Endpoint (SUR): Blood pressure
Study 9689551 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9689551 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9689551 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7737258 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28603225 — Surrogate Endpoint (SUR): Serum uric acid
Study 28603225 — Surrogate Endpoint (SUR): Serum creatinine
Study 28603225 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28603225 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28603225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27399077 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18797304 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 16189173 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10657578 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 10657578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10657578 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10657578 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8866634 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 1593512 — Surrogate Endpoint (SUR): Blood pressure
Study 29923286 — Surrogate Endpoint (SUR): Blood pressure
Study 22398753 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 22398753 — Surrogate Endpoint (SUR): Blood pressure
Study 30906562 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 30906562 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 30906562 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 30906562 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 21669016 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31434809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26267590 — Surrogate Endpoint (SUR): Blood pressure
Study 21222064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21222064 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21222064 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21222064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21222064 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16533286 — Predictive Biomarker (PRD): NAAA mRNA
Genes: NAAA; ASAHL; PLT
Study 29387874 — Predictive Biomarker (PRD): POU5F1 mRNA
Genes: POU5F1; OCT3; OCT4; OTF3
Study 20593350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20593350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20593350 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 16689755 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15558071 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 25362163 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20449538 — Surrogate Endpoint (SUR): Blood pressure
Study 14738209 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29239867 — Surrogate Endpoint (SUR): Blood pressure
Study 25549485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25549485 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25549485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30856652 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 23363643 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 23363643 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 19476583 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31678224 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 31678224 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 31369355 — Surrogate Endpoint (SUR): Blood pressure
Study 31369355 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24858257 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 24858257 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 11158042 — Surrogate Endpoint (SUR): Bone mineral density
Study 11158042 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11158042 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11158042 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9764965 — Surrogate Endpoint (SUR): Blood pressure
Study 15531006 — Surrogate Endpoint (SUR): Blood pressure
Study 29091527 — Surrogate Endpoint (SUR): Blood pressure
Study 23683266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23683266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7425697 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 27375714 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26242117 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study 26242117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19302901 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15449752 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 15449752 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15449752 — Surrogate Endpoint (SUR): Blood pressure
Study 189333 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19114797 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 11739308 — Surrogate Endpoint (SUR): Blood pressure
Study 1565758 — Surrogate Endpoint (SUR): Blood pressure
Study 16036492 — Surrogate Endpoint (SUR): Blood pressure
Study 30614616 — Surrogate Endpoint (SUR): Blood pressure
Study 30614616 — Surrogate Endpoint (SUR): Bone mineral density
Study 12192890 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 7898521 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 2716162 — Surrogate Endpoint (SUR): Blood pressure
Study 28182127 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22145448 — Surrogate Endpoint (SUR): Bone mineral density
Study 19451819 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12637461 — Predictive Biomarker (PRD): Hormone receptor
Study 8898515 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 1381024 — Surrogate Endpoint (SUR): Blood pressure
Study 6387631 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 30786187 — Surrogate Endpoint (SUR): Serum creatinine
Study 7786657 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9072885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21438412 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21438412 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12107665 — Surrogate Endpoint (SUR): Bone mineral density
Study 26124797 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26124797 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23791619 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 16169314 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10577444 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11397963 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11397963 — Surrogate Endpoint (SUR): Serum creatinine
Study 7904930 — Surrogate Endpoint (SUR): Serum potassium
Study 20169461 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15321934 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 20563833 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 8959115 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 28982882 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11165422 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2892430 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2892430 — Surrogate Endpoint (SUR): Blood pressure
Study 30121291 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 30121291 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 30121291 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 30121291 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 30121291 — Predictive Biomarker (PRD): DEFB4A mRNA
Genes: DEFB4A; DEFB102; DEFB2; DEFB4; DEFB4B
Study 16678543 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 16678543 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 15217657 — Surrogate Endpoint (SUR): Blood pressure
Study 16598777 — Surrogate Endpoint (SUR): Serum creatinine
Study 1346172 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 12611766 — Surrogate Endpoint (SUR): Blood pressure
Study 8732695 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27502850 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20697803 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18318083 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25645978 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 24685998 — Surrogate Endpoint (SUR): Blood pressure
Study 30217513 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 24446238 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 24446238 — Surrogate Endpoint (SUR): Blood pressure
Study 12419087 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31655788 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 27997064 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21054770 — Surrogate Endpoint (SUR): Blood pressure
Study 27117004 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 19865105 — Surrogate Endpoint (SUR): Serum uric acid
Study 19865105 — Surrogate Endpoint (SUR): Blood pressure
Study 31388185 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study 31388185 — Predictive Biomarker (PRD): CD8A mRNA
Genes: CD8A; MAL
Study 24499136 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20709302 — Surrogate Endpoint (SUR): Bone mineral density
Study 17547799 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 16362147 — Surrogate Endpoint (SUR): Bone mineral density
Study 26360825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20878389 — Surrogate Endpoint (SUR): Bone mineral density
Study 17182805 — Surrogate Endpoint (SUR): Blood pressure
Study 1583252 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18090458 — Predictive Biomarker (PRD): ELOVL6 mRNA
Genes: ELOVL6; FACE; LCE
Study 31874050 — Surrogate Endpoint (SUR): Serum calcium
Study 29891272 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23299716 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 18283386 — Surrogate Endpoint (SUR): Serum calcium
Study 16093267 — Surrogate Endpoint (SUR): Serum testosterone
Study 16093267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8793613 — Surrogate Endpoint (SUR): Blood pressure
Study 16105050 — Surrogate Endpoint (SUR): Blood pressure
Study 15157949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9478090 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24597534 — Surrogate Endpoint (SUR): Blood pressure
Study 16973692 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 556111 — Surrogate Endpoint (SUR): Blood pressure
Study 19447369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19447369 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 2531184 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2531184 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 2531184 — Surrogate Endpoint (SUR): Blood pressure
Study 31556131 — Surrogate Endpoint (SUR): Blood pressure
Study 23845522 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29133549 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 25105458 — Safety Biomarker (SAF): Reactive oxygen species
Study 18714238 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18714238 — Surrogate Endpoint (SUR): Blood pressure
Study 8410924 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3011885 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29029053 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23648372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11712308 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31594062 — Predictive Biomarker (PRD): TAL1 mRNA
Genes: TAL1; BHLHA17; SCL; TCL5
Study 31594062 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29451912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 29451912 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 29451912 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 29451912 — Predictive Biomarker (PRD): E2F1 mRNA
Genes: E2F1; RBBP3
Study 29451912 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 29451912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29451912 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 29451912 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 29451912 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 29451912 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 22252353 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11872654 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 11872654 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 10195381 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 10195381 — Surrogate Endpoint (SUR): Blood pressure
Study 25888343 — Surrogate Endpoint (SUR): Blood pressure
Study 28450193 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 28450193 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24898537 — Surrogate Endpoint (SUR): Bone mineral density
Study 30265045 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26885819 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 12131074 — Surrogate Endpoint (SUR): Blood pressure
Study 7573997 — Surrogate Endpoint (SUR): Blood pressure
Study 15824055 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10220741 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 110211 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 27328681 — Surrogate Endpoint (SUR): Blood pressure
Study 22340793 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 22340793 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 15716195 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 31073737 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 22260080 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16891677 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 6487947 — Surrogate Endpoint (SUR): Blood pressure
Study 26751765 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23585666 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 20937051 — Surrogate Endpoint (SUR): Serum creatinine
Study 18384418 — Predictive Biomarker (PRD): CACNA1A mRNA
Genes: CACNA1A; CACH4; CACN3; CACNL1A4
Study 18384418 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 16730418 — Surrogate Endpoint (SUR): Bone mineral density
Study 14680611 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 14680611 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26332311 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 20579405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16182039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23039030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23039030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21142812 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21142812 — Surrogate Endpoint (SUR): Blood pressure
Study 21142812 — Surrogate Endpoint (SUR): Serum creatinine
Study 12953850 — Surrogate Endpoint (SUR): Blood pressure
Study 12953850 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10703679 — Surrogate Endpoint (SUR): Blood pressure
Study 7870914 — Surrogate Endpoint (SUR): Blood pressure
Study 29574518 — Surrogate Endpoint (SUR): Bone mineral density
Study 18356403 — Surrogate Endpoint (SUR): Blood pressure
Study 2056262 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2056262 — Surrogate Endpoint (SUR): Serum uric acid
Study 15175435 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11753186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11753186 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 29471124 — Surrogate Endpoint (SUR): Bone mineral density
Study 23147684 — Surrogate Endpoint (SUR): Blood pressure
Study 24959618 — Surrogate Endpoint (SUR): Blood pressure
Study 15832830 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12875727 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 12875727 — Surrogate Endpoint (SUR): Bone mineral density
Study 2145212 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30755574 — Surrogate Endpoint (SUR): Blood pressure
Study 22814367 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22814367 — Surrogate Endpoint (SUR): Blood pressure
Study 22814367 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10446945 — Surrogate Endpoint (SUR): Serum creatinine
Study 10446945 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28082335 — Surrogate Endpoint (SUR): Blood pressure
Study 25474535 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 3092610 — Surrogate Endpoint (SUR): Blood pressure
Study 29622823 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29622823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3978827 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26339899 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 17083352 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17083352 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 14660453 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 14660453 — Surrogate Endpoint (SUR): Blood pressure
Study 7938556 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3130175 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11296186 — Surrogate Endpoint (SUR): Serum creatinine
Study 26029985 — Surrogate Endpoint (SUR): Bone mineral density
Study 15024300 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15024300 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11122839 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 11122839 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22889406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22889406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22889406 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22889406 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 8872133 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1518317 — Surrogate Endpoint (SUR): Blood pressure
Study 22784777 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 7935654 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16003735 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28832393 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18208600 — Safety Biomarker (SAF): Hyaluronic acid
Study 10883868 — Surrogate Endpoint (SUR): Probing pocket depth
Study 1580284 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1580284 — Surrogate Endpoint (SUR): Blood pressure
Study 29340321 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 29340321 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 24127838 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8582783 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17489733 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 25159300 — Surrogate Endpoint (SUR): Blood pressure