TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17207028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15311830 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 2636644 — Safety Biomarker (SAF): 51Cr-EDTA
Study 2636644 — Surrogate Endpoint (SUR): Serum creatinine
Study 2636644 — Surrogate Endpoint (SUR): Blood pressure
Study 21522097 — Surrogate Endpoint (SUR): Blood pressure
Study 20137491 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 16885180 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9060793 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10559513 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8698011 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19017314 — Surrogate Endpoint (SUR): Blood pressure
Study 24321374 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 8791276 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8791276 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16416643 — Safety Biomarker (SAF): Hyaluronic acid
Study 12601486 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 10509569 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8984939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11264639 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 18760137 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18760137 — Surrogate Endpoint (SUR): Blood pressure
Study 12766934 — Surrogate Endpoint (SUR): Blood pressure
Study 1683422 — Safety Biomarker (SAF): Interleukin 1
Study 19863450 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19151458 — Surrogate Endpoint (SUR): Blood pressure
Study 11388472 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 11388472 — Surrogate Endpoint (SUR): Bone mineral density
Study 31088176 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19332969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11197756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7871035 — Safety Biomarker (SAF): DRD2
Study 3250315 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 3250315 — Surrogate Endpoint (SUR): Blood pressure
Study 30287671 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study 30287671 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31396815 — Surrogate Endpoint (SUR): Blood pressure
Study 23435032 — Safety Biomarker (SAF): Hyaluronic acid
Study 21912122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21912122 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21912122 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21912122 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21912122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19052054 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19052054 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14980929 — Surrogate Endpoint (SUR): Blood pressure
Study 8148356 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8148356 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 30655509 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 16961773 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9109860 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9109860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9109860 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8258118 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30064301 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10178659 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8157786 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 21640689 — Surrogate Endpoint (SUR): Blood pressure
Study 16816554 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1919633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1919633 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6925851 — Surrogate Endpoint (SUR): Blood pressure
Study 31441409 — Monitoring Biomarker (MOI): Procalcitonin
Study 26645521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26645521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26645521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26645521 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23178539 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 21465247 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28315922 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 21122658 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10561318 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29655624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17387129 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17387129 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17387129 — Surrogate Endpoint (SUR): Blood pressure
Study 11694947 — Surrogate Endpoint (SUR): Serum creatinine
Study 11720426 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9219909 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8238379 — Surrogate Endpoint (SUR): Blood pressure
Study 22305809 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22305809 — Surrogate Endpoint (SUR): Serum creatinine
Study 18807007 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18807007 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18807007 — Surrogate Endpoint (SUR): Serum creatinine
Study 14607210 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14607210 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19262464 — Surrogate Endpoint (SUR): Serum sodium
Study 16138563 — Surrogate Endpoint (SUR): Blood pressure
Study 31435005 — Surrogate Endpoint (SUR): Blood pressure
Study 26074314 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 7663574 — Safety Biomarker (SAF): Reactive oxygen species
Study 30656889 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10877165 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 7692166 — Surrogate Endpoint (SUR): Blood pressure
Study 3549869 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31015198 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 29486131 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22001664 — Surrogate Endpoint (SUR): Blood pressure
Study 9466024 — Surrogate Endpoint (SUR): Blood pressure
Study 22949583 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 20580572 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18167121 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18167121 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12623165 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12623165 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 29368537 — Surrogate Endpoint (SUR): Bone mineral density
Study 22840917 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16612708 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16612708 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26113439 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26113439 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 11309019 — Surrogate Endpoint (SUR): Blood pressure
Study 3031150 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3031150 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18568324 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 18568324 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15768198 — Surrogate Endpoint (SUR): Blood pressure
Study 22241898 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 17392721 — Predictive Biomarker (PRD): REEP5 mRNA
Genes: REEP5; C5orf18; DP1; TB2
Study 10067815 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 7564362 — Surrogate Endpoint (SUR): Blood pressure
Study 7564362 — Surrogate Endpoint (SUR): Serum uric acid
Study 29956019 — Surrogate Endpoint (SUR): Bone mineral density
Study 28596274 — Surrogate Endpoint (SUR): Blood pressure
Study 15766363 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 15766363 — Surrogate Endpoint (SUR): Probing pocket depth
Study 27830924 — Surrogate Endpoint (SUR): Blood pressure
Study 27830924 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21114791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19526394 — Surrogate Endpoint (SUR): Serum creatinine
Study 19526394 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 15453924 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 23018469 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 19910173 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 19910173 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 19910173 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16043728 — Surrogate Endpoint (SUR): Blood pressure
Study 6164789 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28291046 — Predictive Biomarker (PRD): DDN mRNA
Genes: DDN; KIAA0749
Study 28291046 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 2193475 — Surrogate Endpoint (SUR): Blood pressure
Study 6998868 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 26808827 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24774670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24774670 — Safety Biomarker (SAF): Human leucocyte antigen
Study 12571527 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1602935 — Surrogate Endpoint (SUR): Blood pressure
Study 31272502 — Surrogate Endpoint (SUR): Blood pressure
Study 10894639 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10894639 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6837336 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21080348 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 21080348 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24727234 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 1720833 — Surrogate Endpoint (SUR): Blood pressure
Study 6173518 — Surrogate Endpoint (SUR): Blood pressure
Study 9606471 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23564348 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17954367 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19271166 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19271166 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16293960 — Surrogate Endpoint (SUR): Blood pressure
Study 1659495 — Surrogate Endpoint (SUR): Blood pressure
Study 26884592 — Surrogate Endpoint (SUR): Pathological complete response
Study 25225081 — Surrogate Endpoint (SUR): Serum calcium
Study 25225081 — Surrogate Endpoint (SUR): Bone mineral density
Study 18647201 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 28941056 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 28941056 — Surrogate Endpoint (SUR): Blood pressure
Study 6753547 — Surrogate Endpoint (SUR): Blood pressure
Study 14514628 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7963115 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29723235 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 21786434 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 15080785 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15080785 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15080785 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15080785 — Surrogate Endpoint (SUR): Serum testosterone
Study 22682536 — Predictive Biomarker (PRD): CTPS1 mRNA
Genes: CTPS1; CTPS
Study 18356694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18356694 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 18356694 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18356694 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 14613023 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24607303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24607303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30845291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15620437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26746184 — Surrogate Endpoint (SUR): Blood pressure
Study 21474498 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15276394 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11352981 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 26412349 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26412349 — Predictive Biomarker (PRD): Hormone receptor
Study 23679351 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 23679351 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12786700 — Safety Biomarker (SAF): Hyaluronic acid
Study 8973725 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6385051 — Surrogate Endpoint (SUR): Blood pressure
Study 16234962 — Surrogate Endpoint (SUR): Serum calcium
Study 16234962 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 2127424 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17550489 — Safety Biomarker (SAF): Reactive oxygen species
Study 9688014 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 338851 — Surrogate Endpoint (SUR): Serum potassium
Study 27548910 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 23556995 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 7527108 — Surrogate Endpoint (SUR): Blood pressure
Study 28111980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28111980 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16681573 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 11781669 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 9264493 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9264493 — Surrogate Endpoint (SUR): Blood pressure
Study 15253730 — Surrogate Endpoint (SUR): Serum creatinine
Study 29538579 — Surrogate Endpoint (SUR): Blood pressure
Study 27496232 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27496232 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27496232 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24241495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24241495 — Safety Biomarker (SAF): IL-6 and IL-10
Study 20147896 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 20147896 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20147896 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20147896 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 14663041 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 11054627 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11054627 — Surrogate Endpoint (SUR): Blood pressure
Study 11054627 — Surrogate Endpoint (SUR): Serum creatinine
Study 1378155 — Surrogate Endpoint (SUR): Blood pressure
Study 29093302 — Surrogate Endpoint (SUR): Blood pressure
Study 25233662 — Surrogate Endpoint (SUR): Blood pressure
Study 8857017 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 19233760 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 19233760 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 17725246 — Surrogate Endpoint (SUR): Blood pressure
Study 15077101 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24612502 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19009170 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11095060 — Predictive Biomarker (PRD): TGFBI mRNA
Genes: TGFBI; BIGH3
Study 25775249 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25775249 — Surrogate Endpoint (SUR): Blood pressure
Study 23806736 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18085104 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 18085104 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 23188416 — Surrogate Endpoint (SUR): Blood pressure
Study 12855334 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 6814471 — Surrogate Endpoint (SUR): Blood pressure
Study 23343675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23343675 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23343675 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23343675 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21084270 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 21084270 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 21084270 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 17540200 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17540200 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17540200 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 3802704 — Surrogate Endpoint (SUR): Blood pressure
Study 21612468 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11472278 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11472278 — Surrogate Endpoint (SUR): Blood pressure
Study 7521724 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7521724 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 30604674 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 28498189 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18581619 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 3045028 — Surrogate Endpoint (SUR): Serum potassium
Study 22999398 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9442340 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 9048272 — Surrogate Endpoint (SUR): Blood pressure
Study 18779616 — Surrogate Endpoint (SUR): Bone mineral density
Study 2409356 — Surrogate Endpoint (SUR): Blood pressure
Study 19443132 — Surrogate Endpoint (SUR): Blood pressure
Study 15580176 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8288727 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8288727 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8288727 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30166301 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 25602687 — Surrogate Endpoint (SUR): Serum sodium
Study 24200273 — Predictive Biomarker (PRD): PTBP2 mRNA
Genes: PTBP2; NPTB; PTB; PTBLP
Study 9123736 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11395041 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 11395041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 29879606 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 23733326 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 10230328 — Surrogate Endpoint (SUR): Blood pressure
Study 8721349 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 28388294 — Surrogate Endpoint (SUR): Blood pressure
Study 24552382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24552382 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16870661 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 16870661 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3