TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12118904 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25736134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23128283 — Surrogate Endpoint (SUR): Blood pressure
Study 27431995 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22537281 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 27409799 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21993890 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21993890 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 21993890 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2857610 — Surrogate Endpoint (SUR): Blood pressure
Study 27357800 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27357800 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27357800 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 27357800 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27357800 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 27357800 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 24450471 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 17511187 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27919901 — Predictive Biomarker (PRD): CD101 mRNA
Genes: CD101; EWI101; IGSF2; V7
Study 2242456 — Surrogate Endpoint (SUR): Blood pressure
Study 16963261 — Surrogate Endpoint (SUR): Bone mineral density
Study 8111210 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 25267802 — Surrogate Endpoint (SUR): Blood pressure
Study 16350719 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 22547251 — Surrogate Endpoint (SUR): Blood pressure
Study 12421432 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8727946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18694444 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 1723468 — Surrogate Endpoint (SUR): Blood pressure
Study 31752522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29913229 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26786780 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26786780 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18347838 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 30252149 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28968858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24507941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22973178 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17341711 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17341711 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17341711 — Surrogate Endpoint (SUR): Blood pressure
Study 7530677 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31667685 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31667685 — Surrogate Endpoint (SUR): Serum testosterone
Study 27279471 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27279471 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11076816 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31215837 — Surrogate Endpoint (SUR): Blood pressure
Study 26423685 — Surrogate Endpoint (SUR): Serum creatinine
Study 2711155 — Surrogate Endpoint (SUR): Blood pressure
Study 2711155 — Surrogate Endpoint (SUR): Serum sodium
Study 25434635 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3080882 — Surrogate Endpoint (SUR): Blood pressure
Study 3080882 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3080882 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28295221 — Predictive Biomarker (PRD): TOX mRNA
Genes: TOX; KIAA0808
Study 25462898 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27323697 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 19785625 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8550646 — Surrogate Endpoint (SUR): Serum sodium
Study 25386945 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 19936725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15609278 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15609278 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 15609278 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15609278 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21492364 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31624391 — Surrogate Endpoint (SUR): Blood pressure
Study 20100962 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31631058 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 25140039 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9545677 — Surrogate Endpoint (SUR): Blood pressure
Study 3296295 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12806381 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 6336981 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 26993976 — Predictive Biomarker (PRD): EPHB2 mRNA
Genes: EPHB2; DRT; EPHT3; EPTH3; ERK; HEK5; TYRO5
Study 15733479 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 9550505 — Predictive Biomarker (PRD): GNS mRNA
Genes: GNS
Study 29464680 — Surrogate Endpoint (SUR): Serum creatinine
Study 27058906 — Surrogate Endpoint (SUR): Serum calcium
Study 25027749 — Surrogate Endpoint (SUR): Serum creatinine
Study 23022759 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9053970 — Safety Biomarker (SAF): 51Cr-EDTA
Study 2149912 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 2149912 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28089680 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28089680 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 25575067 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study 25575067 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25575067 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study 25575067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25575067 — Safety Biomarker (SAF): Reactive oxygen species
Study 25575067 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10480500 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 10480500 — Surrogate Endpoint (SUR): Blood pressure
Study 26499256 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 23708174 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 23708174 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 23708174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6804164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 6804164 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29558784 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 29558784 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30091945 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 15875108 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 1710741 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1710741 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31586310 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 22172907 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 24247736 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 3087709 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 18333598 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16552342 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 25463375 — Surrogate Endpoint (SUR): Blood pressure
Study 20191582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25338498 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FasL mRNA
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 15078261 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 2657616 — Safety Biomarker (SAF): Urinary total protein
Study 2657616 — Surrogate Endpoint (SUR): Serum creatinine
Study 16296701 — Surrogate Endpoint (SUR): Blood pressure
Study 6212561 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25381429 — Surrogate Endpoint (SUR): Serum creatinine
Study 11159017 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11159017 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 11159017 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 11159017 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9644630 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 23668478 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 23668478 — Surrogate Endpoint (SUR): Blood pressure
Study 23178855 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 23892922 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21350110 — Surrogate Endpoint (SUR): Blood pressure
Study 22167565 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 18277195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18277195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12946547 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 12946547 — Surrogate Endpoint (SUR): Blood pressure
Study 12946547 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12946547 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12946547 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7994166 — Surrogate Endpoint (SUR): Blood pressure
Study 19127179 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 31827679 — Surrogate Endpoint (SUR): Blood pressure
Study 31827679 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24138460 — Surrogate Endpoint (SUR): Serum creatinine
Study 20079166 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30894208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9069476 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 14634544 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 14634544 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31407311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 4015285 — Surrogate Endpoint (SUR): Blood pressure
Study 27281561 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27281561 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 27281561 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27281561 — Monitoring Biomarker (MOI): Cell-free DNA
Study 24140730 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22564837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22564837 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 22564837 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20587580 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 12214831 — Surrogate Endpoint (SUR): Blood pressure
Study 8960845 — Surrogate Endpoint (SUR): Blood pressure
Study 27323615 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Protein S100-P
Genes: S100P; S100E
Study 20339154 — Surrogate Endpoint (SUR): Blood pressure
Study 20339154 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17010609 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 7553230 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21175313 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 21175313 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 31315962 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28479016 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 24373585 — Surrogate Endpoint (SUR): Blood pressure
Study 16634072 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23672102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28498275 — Surrogate Endpoint (SUR): Blood pressure
Study 21632552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21632552 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21632552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30651321 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study 30651321 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30651321 — Surrogate Endpoint (SUR): Blood pressure
Study 28282300 — Surrogate Endpoint (SUR): Bone mineral density
Study 21134693 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15192923 — Surrogate Endpoint (SUR): Blood pressure
Study 20557327 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12689354 — Surrogate Endpoint (SUR): Blood pressure
Study 29506422 — Predictive Biomarker (PRD): DEFB1 mRNA
Genes: DEFB1; BD1; HBD1
Study 26341762 — Surrogate Endpoint (SUR): Serum creatinine
Study 16957424 — Surrogate Endpoint (SUR): Blood pressure
Study 31583611 — Surrogate Endpoint (SUR): Serum potassium
Study 24738111 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 24738111 — Surrogate Endpoint (SUR): Bone mineral density
Study 10546391 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8756737 — Surrogate Endpoint (SUR): Serum testosterone
Study 30262599 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 30262599 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26811525 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22741450 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 21960110 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study 17132650 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15918933 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 10022415 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 31628783 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 31277259 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 31277259 — Predictive Biomarker (PRD): SLC2A2 mRNA
Genes: SLC2A2; GLUT2
Study 10342783 — Surrogate Endpoint (SUR): Blood pressure
Study 2140346 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30652973 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 30652973 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28912129 — Surrogate Endpoint (SUR): Blood pressure
Study 17581195 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17581195 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 17581195 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 15363825 — Surrogate Endpoint (SUR): Blood pressure
Study 9387298 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 29851998 — Surrogate Endpoint (SUR): Blood pressure
Study 31485457 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31485457 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17521300 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 17521300 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 17521300 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17521300 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17521300 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 15363813 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15363813 — Surrogate Endpoint (SUR): Blood pressure
Study 7577850 — Surrogate Endpoint (SUR): Bone mineral density
Study 7033744 — Surrogate Endpoint (SUR): Blood pressure
Study 15573713 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15573713 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27603954 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24620447 — Surrogate Endpoint (SUR): Blood pressure
Study 22503212 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22503212 — Surrogate Endpoint (SUR): Serum calcium
Study 9663484 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9663484 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9663484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9663484 — Safety Biomarker (SAF): Interleukin 1
Study 2883990 — Surrogate Endpoint (SUR): Blood pressure
Study 21486801 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 16916336 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15518756 — Surrogate Endpoint (SUR): Serum creatinine
Study 23419987 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17184491 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 11864854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 465276 — Surrogate Endpoint (SUR): Blood pressure
Study 24356622 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24356622 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15619071 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 15619071 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 15619071 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 24714934 — Surrogate Endpoint (SUR): Bone mineral density
Study 18027255 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30678709 — Surrogate Endpoint (SUR): Blood pressure
Study 18701270 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 18701270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18701270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8139136 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3524181 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28589472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20076850 — Surrogate Endpoint (SUR): Serum creatinine
Study 15821396 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 8577017 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8577017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31950384 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31950384 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 30771790 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 30771790 — Safety Biomarker (SAF): Reactive oxygen species
Study 30771790 — Surrogate Endpoint (SUR): Sperm parameters
Study 28166118 — Surrogate Endpoint (SUR): Blood pressure
Study 12556011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12556011 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8849475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31278280 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25497362 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 20031380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20031380 — Surrogate Endpoint (SUR): Blood pressure
Study 12226038 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2670019 — Surrogate Endpoint (SUR): Bone mineral density
Study 2670019 — Surrogate Endpoint (SUR): Serum calcium
Study 2670019 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2670019 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 2670019 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 2670019 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29710336 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29710336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25247897 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16114087 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16114087 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31280470 — Surrogate Endpoint (SUR): Blood pressure