TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT05573607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01327014 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01327014 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00425451 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00748891 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02518399 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03375424 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04306419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01324076 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT05667311 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT00524797 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04001777 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00897858 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03102632 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT01692327 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study NCT01692327 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study NCT01288105 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT01564498 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02725372 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01240590 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01240590 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT01240590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01240590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01240590 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01240590 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02817256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02258698 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study NCT01367002 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00004496 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00004496 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT00269022 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT01828021 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04343417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT03417700 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT05750719 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00048932 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01701141 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT03776604 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03929471 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00466037 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03066921 — Predictive Biomarker (PRD); Safety Biomarker (SAF): NRK mRNA
Genes: NRK
Study NCT03066921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00754325 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00386685 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05019859 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT04084665 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00903864 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00296790 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01293292 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03727672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03727672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01539252 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT05977010 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03068312 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01097954 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00439218 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT04680598 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02823340 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01829711 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT02504762 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study NCT00003167 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02636114 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00162409 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00910962 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT00910962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01857999 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01857999 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03333824 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03333824 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT04653688 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study NCT04653688 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT01688505 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02418689 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01676298 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04597931 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01230970 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT02580799 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04999072 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00476294 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00476294 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00871702 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01662193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01662193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02476929 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03338166 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT05654285 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT05654285 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT01319058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01319058 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01319058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00500604 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03847727 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01498614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03560804 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00739674 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04373967 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study NCT04144088 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03553225 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01138657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01000649 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01394835 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00879632 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00879632 — Safety Biomarker (SAF): BDNF
Study NCT01961232 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT01961232 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03152435 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02368652 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02629666 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00552591 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00552591 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02442037 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04305496 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04305496 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04305496 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study NCT04305496 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04305496 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01585623 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01585623 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01585623 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01049490 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03393559 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05479565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00386399 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT01068132 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01068132 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02637063 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00201045 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01487460 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00266383 — Predictive Biomarker (PRD): SLC11A1 mRNA
Genes: SLC11A1; LSH; NRAMP; NRAMP1
Study NCT04053699 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02315118 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study NCT03282253 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT05171426 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT01208506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04417309 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04417309 — Safety Biomarker (SAF): BDNF
Study NCT02630186 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03492853 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study NCT03492853 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study NCT03492853 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study NCT03492853 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT00264888 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00578344 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03433885 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01303471 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00126867 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT02525185 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00923078 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study NCT04261309 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study NCT02173288 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT03663920 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02203799 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00681109 — Safety Biomarker (SAF): Interleukin 1
Study NCT03316690 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT04150809 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00944983 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02216084 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT01052272 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02166684 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02431169 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01790542 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01960972 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04214457 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01323790 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT02562274 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02562274 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT04101188 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01759966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study NCT01745666 — Predictive Biomarker (PRD): KCNQ1 mRNA
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study NCT01745666 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study NCT00147615 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03434600 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02138838 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT00154544 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT01666821 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00375388 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04577326 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT04577326 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00502684 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study NCT00502684 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03033667 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02002689 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study NCT02002689 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH
Study NCT01411657 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study NCT03682003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02734706 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02734706 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT03014791 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03865732 — Predictive Biomarker (PRD): PCDH19 mRNA
Genes: PCDH19; KIAA1313
Study NCT01286311 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00905294 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00486954 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00486954 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00486954 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01482325 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00780793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00239967 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00239967 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01690000 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02730091 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02730091 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03190811 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04328467 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00546156 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00546156 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00546156 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00005635 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00825318 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00003412 — Safety Biomarker (SAF): Interleukin 12
Study NCT00001899 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02959411 — Surrogate Endpoint (SUR): Serum sodium
Study NCT03006718 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01507142 — Predictive Biomarker (PRD): UCN2 mRNA
Genes: UCN2; SRP; URP
Study NCT00787475 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00787475 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04140526 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT02733484 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03676504 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03676504 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT02285088 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03860129 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT00620139 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00620139 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05662930 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001526 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02574286 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02135315 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05804955 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study NCT03150589 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04890626 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00046475 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04780607 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT00056524 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT02648555 — Safety Biomarker (SAF): BDNF
Study NCT02648555 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02648555 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT03500276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01049854 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04070937 — Predictive Biomarker (PRD): COCH mRNA
Genes: COCH; COCH5B2; UNQ257/PRO294
Study NCT01403285 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02871245 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT02565589 — Safety Biomarker (SAF): Interleukin 12
Study NCT01884571 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00453440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study NCT00424502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00213759 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03346590 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00000532 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00000532 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00000532 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03063021 — Predictive Biomarker (PRD): TOLLIP mRNA
Genes: TOLLIP
Study NCT02445404 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT00205738 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study NCT00929526 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00994708 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT04169802 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02174978 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT04671121 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02024503 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT00006084 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT01630668 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT04453488 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03006393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01005030 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT00855296 — Predictive Biomarker (PRD): F2RL3 mRNA
Genes: F2RL3; PAR4
Study NCT01670877 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00926107 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT04699578 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS