TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10922430 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8757514 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 17217710 — Surrogate Endpoint (SUR): Blood pressure
Study 8349327 — Surrogate Endpoint (SUR): Blood pressure
Study 26964731 — Surrogate Endpoint (SUR): Bone mineral density
Study 22437412 — Surrogate Endpoint (SUR): Blood pressure
Study 18495838 — Surrogate Endpoint (SUR): Blood pressure
Study 17302259 — Monitoring Biomarker (MOI): HBV DNA
Study 10750762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26323809 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 26323809 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26323809 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 12875064 — Surrogate Endpoint (SUR): Bone mineral density
Study 9124058 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 27873388 — Surrogate Endpoint (SUR): Blood pressure
Study 25421976 — Surrogate Endpoint (SUR): Blood pressure
Study 14962687 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 14962687 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14962687 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9598253 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3280493 — Surrogate Endpoint (SUR): Blood pressure
Study 24002278 — Surrogate Endpoint (SUR): Blood pressure
Study 24002278 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30614406 — Predictive Biomarker (PRD): ATF4 mRNA
Genes: ATF4; CREB2; TXREB
Study 30614406 — Predictive Biomarker (PRD): XBP1 mRNA
Genes: XBP1; TREB5; XBP2
Study 30614406 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 30614406 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 27456910 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 27456910 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 27456910 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27456910 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 9435408 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12142560 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8698787 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 19645851 — Safety Biomarker (SAF): Reactive oxygen species
Study 23846872 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 10671847 — Surrogate Endpoint (SUR): Blood pressure
Study 30597865 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 24253615 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 24253615 — Surrogate Endpoint (SUR): Blood pressure
Study 1314260 — Surrogate Endpoint (SUR): Blood pressure
Study 23928836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23928836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23928836 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 10867543 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 10867543 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 10867543 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 9327192 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27821114 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 8772558 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 26791606 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 9576151 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28259610 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28259610 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 28259610 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 24481570 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22104618 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 19577277 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 27095167 — Surrogate Endpoint (SUR): Blood pressure
Study 26775373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14740953 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 10674459 — Surrogate Endpoint (SUR): Serum creatinine
Study 2645914 — Surrogate Endpoint (SUR): Blood pressure
Study 26089546 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9112894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31784345 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29631782 — Surrogate Endpoint (SUR): Bone mineral density
Study 16224525 — Surrogate Endpoint (SUR): Blood pressure
Study 12005077 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 12005077 — Surrogate Endpoint (SUR): Bone mineral density
Study 10068928 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10068928 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20857170 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17434599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17434599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7938398 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7938398 — Surrogate Endpoint (SUR): Blood pressure
Study 7938398 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27267081 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18063394 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 15910557 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10473054 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 2667865 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 30765033 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25799356 — Surrogate Endpoint (SUR): Blood pressure
Study 24195548 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9869105 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25692251 — Surrogate Endpoint (SUR): Blood pressure
Study 7594512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7594512 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 2299797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2299797 — Safety Biomarker (SAF): Interleukin 1
Study 28803925 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29048238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25394438 — Surrogate Endpoint (SUR): Serum creatinine
Study 15460215 — Surrogate Endpoint (SUR): Blood pressure
Study 9161933 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 27605403 — Surrogate Endpoint (SUR): Blood pressure
Study 8675938 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 1801057 — Surrogate Endpoint (SUR): Blood pressure
Study 25124998 — Safety Biomarker (SAF): miR-652
Genes: MIR652
Study 25124998 — Safety Biomarker (SAF): miR-103
Study 17546496 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11772148 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11772148 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11772148 — Surrogate Endpoint (SUR): Serum uric acid
Study 7948822 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27873046 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 27873046 — Surrogate Endpoint (SUR): Bone mineral density
Study 26934167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26934167 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24376273 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 8582132 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31407967 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 31407967 — Predictive Biomarker (PRD): Hormone receptor
Study 11447496 — Surrogate Endpoint (SUR): Blood pressure
Study 30948215 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 23787721 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29171486 — Safety Biomarker (SAF): BDNF
Study 23273292 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16565627 — Surrogate Endpoint (SUR): Blood pressure
Study 8617132 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 1418064 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1418064 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 17535971 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17535971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7363678 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31275980 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15522364 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 9213204 — Surrogate Endpoint (SUR): Blood pressure
Study 20515959 — Surrogate Endpoint (SUR): Blood pressure
Study 17092412 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 31197507 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 31197507 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study 31197507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31197507 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 15974350 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31552704 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31552704 — Surrogate Endpoint (SUR): Blood pressure
Study 31501887 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24451954 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24451954 — Surrogate Endpoint (SUR): Serum creatinine
Study 24451954 — Surrogate Endpoint (SUR): Blood pressure
Study 23019074 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 23019074 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 23019074 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 23019074 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 9089428 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30894206 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27039080 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 16310021 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16310021 — Surrogate Endpoint (SUR): Blood pressure
Study 8912751 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8373975 — Surrogate Endpoint (SUR): Blood pressure
Study 27154174 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 27154174 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23402387 — Surrogate Endpoint (SUR): Serum potassium
Study 19527323 — Surrogate Endpoint (SUR): Blood pressure
Study 9234829 — Surrogate Endpoint (SUR): Blood pressure
Study 27710915 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 27710915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27710915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25048345 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22203755 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 22203755 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 16013010 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 16013010 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16013010 — Surrogate Endpoint (SUR): Serum creatinine
Study 22853848 — Surrogate Endpoint (SUR): Blood pressure
Study 1965403 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1965403 — Surrogate Endpoint (SUR): Blood pressure
Study 31443893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22055504 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 22055504 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 22055504 — Surrogate Endpoint (SUR): Blood pressure
Study 16925756 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 14517191 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 1410164 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 3935346 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 25073857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25073857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25073857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15385809 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 24267730 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24267730 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24267730 — Predictive Biomarker (PRD): Hormone receptor
Study 21603651 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21603651 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11996476 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23057495 — Surrogate Endpoint (SUR): Pathological complete response
Study 20577750 — Safety Biomarker (SAF): Hyaluronic acid
Study 19344224 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 16281654 — Surrogate Endpoint (SUR): Bone mineral density
Study 9204353 — Surrogate Endpoint (SUR): Blood pressure
Study 9829838 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9829838 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9829838 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9829838 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 25600248 — Surrogate Endpoint (SUR): Serum uric acid
Study 24405838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24405838 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 17414581 — Surrogate Endpoint (SUR): Blood pressure
Study 10472217 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 10472217 — Surrogate Endpoint (SUR): Serum creatinine
Study 1833901 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 6315025 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27310905 — Surrogate Endpoint (SUR): Blood pressure
Study 10354967 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28485429 — Predictive Biomarker (PRD): SERPINB1 mRNA
Genes: SERPINB1; ELANH2; MNEI; PI2
Study 22082198 — Surrogate Endpoint (SUR): Blood pressure
Study 26583672 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 23269596 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22136261 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 22136261 — Surrogate Endpoint (SUR): Blood pressure
Study 2760919 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2760919 — Surrogate Endpoint (SUR): Blood pressure
Study 23603862 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23603862 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 23603862 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study 23603862 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 8941027 — Surrogate Endpoint (SUR): Blood pressure
Study 12810609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12810609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12810609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27930697 — Surrogate Endpoint (SUR): Blood pressure
Study 12874742 — Safety Biomarker (SAF): Prognostic nutrition index
Study 8539676 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 2146231 — Surrogate Endpoint (SUR): Blood pressure
Study 31931884 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10832765 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20075788 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18296130 — Predictive Biomarker (PRD): MAG mRNA
Genes: MAG; GMA
Study 7742578 — Surrogate Endpoint (SUR): Bone mineral density
Study 7742578 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2258784 — Surrogate Endpoint (SUR): Blood pressure
Study 7836717 — Surrogate Endpoint (SUR): Serum creatinine
Study 27056738 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17012867 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 2877953 — Surrogate Endpoint (SUR): Blood pressure
Study 23481576 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 26755229 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26755229 — Surrogate Endpoint (SUR): Blood pressure
Study 14716631 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6761136 — Surrogate Endpoint (SUR): Blood pressure
Study 21810843 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20623976 — Predictive Biomarker (PRD): PHLDA2 mRNA
Genes: PHLDA2; BWR1C; HLDA2; IPL; TSSC3
Study 10460524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10460524 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7876922 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22448010 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 22448010 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14607201 — Surrogate Endpoint (SUR): Blood pressure
Study 1932613 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 21617191 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 21617191 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21617191 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8031419 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8031419 — Surrogate Endpoint (SUR): Blood pressure
Study 27669638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23490388 — Monitoring Biomarker (MOI): HBV DNA
Study 49472 — Surrogate Endpoint (SUR): Blood pressure
Study 21183937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21183937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19933787 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29459111 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 1536156 — Surrogate Endpoint (SUR): Blood pressure
Study 25222285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20186971 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 28295985 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17596432 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17596432 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17596432 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17596432 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 2831117 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2831117 — Surrogate Endpoint (SUR): Blood pressure
Study 2831117 — Surrogate Endpoint (SUR): Serum potassium
Study 30105460 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30105460 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 14564144 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9186890 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 24192331 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24192331 — Predictive Biomarker (PRD): Hormone receptor
Study 16843075 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10391417 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6873132 — Surrogate Endpoint (SUR): Blood pressure
Study 26961929 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 26961929 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 26961929 — Predictive Biomarker (PRD): PLIN2 mRNA
Genes: PLIN2; ADFP
Study 24505290 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22062358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20710062 — Predictive Biomarker (PRD): TG mRNA
Genes: TG