TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03086538 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03770676 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study NCT01679184 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00837122 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04436120 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study NCT04436120 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04318301 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT03867110 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04850625 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01990755 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study NCT00635050 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT03728686 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01686321 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00846482 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT03804255 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03804255 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03804255 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study NCT03804255 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT02214628 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01915446 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT04018703 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02225184 — Predictive Biomarker (PRD): OPRD1 mRNA
Genes: OPRD1; OPRD
Study NCT04456894 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03838367 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT00436267 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT02272699 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01027351 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study NCT00373347 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT03726879 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00686946 — Predictive Biomarker (PRD): SLC11A1 mRNA
Genes: SLC11A1; LSH; NRAMP; NRAMP1
Study NCT03928015 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study NCT06624345 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00802919 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study NCT00802919 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT05764083 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05695573 — Safety Biomarker (SAF): Uromodulin
Genes: UMOD
Study NCT04194450 — Safety Biomarker (SAF): BDNF
Study NCT00875407 — Safety Biomarker (SAF): DRD2
Study NCT02933151 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00071994 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02115672 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT03823482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03823482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06549062 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study NCT00684294 — Predictive Biomarker (PRD): TGFB2 mRNA
Genes: TGFB2
Study NCT00684294 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00019838 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study NCT02317445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01893086 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04481932 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04481932 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT03302156 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03578263 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT03474484 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03474484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03474484 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01601561 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00879372 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03713411 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01720836 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT03982173 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03982173 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT02414230 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03837769 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04726046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00067639 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03808077 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT02309567 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00692562 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT02175290 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study NCT02808611 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT03365609 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00578214 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03847012 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02543216 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study NCT01974947 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT00916526 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02395627 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02261610 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03198546 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT03877471 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01468324 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT01059279 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study NCT00428311 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03925246 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03925246 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT05214508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00567229 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03678116 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06135831 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00437866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00437866 — Safety Biomarker (SAF): Interleukin 1
Study NCT00437866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00502593 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04087746 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03601507 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT03601507 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03601507 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01025206 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT04134936 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04248452 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00092716 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04787341 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03403699 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03403699 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT00236665 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01461213 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study NCT03014414 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03353584 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03968042 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02344472 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02344472 — Predictive Biomarker (PRD): Hormone receptor
Study NCT06098352 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03435107 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study NCT00757718 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03456076 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04415151 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04159155 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT04425239 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT00603538 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT03295942 — Predictive Biomarker (PRD): TNFRSF18 mRNA
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study NCT01125228 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02434393 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05001919 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT01808170 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02687620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04537156 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01417988 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03497702 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03497702 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03992872 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03076151 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT00150566 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT05310929 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01338727 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02956148 — Predictive Biomarker (PRD): PDE10A mRNA
Genes: PDE10A
Study NCT03574363 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02180113 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04150497 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT02712866 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT03702543 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06644677 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00751036 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT00607477 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00607477 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01361165 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01384045 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01384045 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03705026 — Predictive Biomarker (PRD): HTR3A mRNA
Genes: HTR3A; 5HT3R; HTR3
Study NCT03705026 — Predictive Biomarker (PRD): TACR1 mRNA
Genes: TACR1; NK1R; TAC1R
Study NCT01824836 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01824836 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study NCT00892866 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT01588925 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00991978 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00991978 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03573089 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT02025218 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00949039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03344705 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03510715 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03510715 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03510715 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05007158 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01182454 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04026737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT04206787 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04206787 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03683082 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00804583 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04134325 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT01898676 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT01895140 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01655446 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT01063569 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00946114 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01554592 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02512939 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01893450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01893450 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02050399 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02050399 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02050399 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02440373 — Safety Biomarker (SAF): Cytochrome c
Study NCT02463435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02463435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02463435 — Predictive Biomarker (PRD): ADRB3 mRNA
Genes: ADRB3; ADRB3R; B3AR
Study NCT02463435 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01211665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04282902 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01416831 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01542944 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02383823 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03315026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00567879 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01370109 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03329131 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study NCT00001738 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00001738 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03277872 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02808884 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01840072 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01871922 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04048837 — Predictive Biomarker (PRD): A2M mRNA
Genes: A2M; CPAMD5; FWP007
Study NCT04048837 — Predictive Biomarker (PRD): CMA1 mRNA
Genes: CMA1; CYH; CYM
Study NCT04048837 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04048837 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT06322901 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT03510533 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01942460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02392169 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT02392169 — Predictive Biomarker (PRD): SULT2A1 mRNA
Genes: SULT2A1; HST; STD
Study NCT02392169 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study NCT02392169 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study NCT03809351 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01285232 — Safety Biomarker (SAF): Interleukin 1
Study NCT01323374 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study NCT01498380 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00121966 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03078231 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03601143 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02647385 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT00938340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04280783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02072057 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT02072057 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT02072057 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study NCT02072057 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study NCT00605657 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02447406 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00465751 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT02674763 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT01904279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00645060 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01145183 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT01145183 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study NCT02801578 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00829465 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT04009226 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study NCT00967252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01565759 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04265651 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT06317883 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02758626 — Predictive Biomarker (PRD): Cyclin-dependent kinase-like 5
Genes: CDKL5; STK9
Study NCT02371187 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02730169 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00928720 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03941561 — Predictive Biomarker (PRD): DIABLO mRNA
Genes: DIABLO; SMAC
Study NCT02162667 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01767987 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT03517605 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03958643 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03958643 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT01334879 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03075228 — Surrogate Endpoint (SUR): Bacterial count
Study NCT01143441 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT02694263 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01926509 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02624479 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT01427686 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05753917 — Predictive Biomarker (PRD): SATB2 mRNA
Genes: SATB2; KIAA1034