TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31550941 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 31550941 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 29097487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17396066 — Surrogate Endpoint (SUR): Blood pressure
Study 17396066 — Safety Biomarker (SAF): Reactive oxygen species
Study 7533343 — Surrogate Endpoint (SUR): Serum creatinine
Study 31558866 — Surrogate Endpoint (SUR): Blood pressure
Study 23482466 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 27928843 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 26433456 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26433456 — Surrogate Endpoint (SUR): Blood pressure
Study 16434455 — Surrogate Endpoint (SUR): Serum testosterone
Study 31694394 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31694394 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27182679 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 27182679 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 27182679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27182679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27182679 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27182679 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7766965 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 7586343 — Surrogate Endpoint (SUR): Blood pressure
Study 2408233 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31388104 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 30838448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22349568 — Surrogate Endpoint (SUR): Serum creatinine
Study 18084799 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 15585598 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 15585598 — Surrogate Endpoint (SUR): Blood pressure
Study 20691834 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 15781499 — Surrogate Endpoint (SUR): Blood pressure
Study 12519833 — Surrogate Endpoint (SUR): Bone mineral density
Study 29960287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29960287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15156934 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15156934 — Surrogate Endpoint (SUR): Bacterial count
Study 25951232 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9227927 — Surrogate Endpoint (SUR): Hematologic response
Study 28058750 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16420077 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18992951 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28817248 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28817248 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24942553 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24942553 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 24942553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9171947 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9171947 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9171947 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30038154 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 26718419 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 23184657 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 10599773 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 1663965 — Surrogate Endpoint (SUR): Blood pressure
Study 30998792 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 8097788 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28171220 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26553684 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 19001327 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28719155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28719155 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28719155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28719155 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25249568 — Surrogate Endpoint (SUR): Bone mineral density
Study 18611200 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 27842495 — Surrogate Endpoint (SUR): Blood pressure
Study 16901645 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 28605608 — Surrogate Endpoint (SUR): Blood pressure
Study 11168509 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28506118 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26564452 — Surrogate Endpoint (SUR): Blood pressure
Study 18305385 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29197999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29197999 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 29197999 — Surrogate Endpoint (SUR): Serum creatinine
Study 22064686 — Surrogate Endpoint (SUR): Blood pressure
Study 22064686 — Surrogate Endpoint (SUR): Serum creatinine
Study 20134098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10511320 — Surrogate Endpoint (SUR): Blood pressure
Study 30717112 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26775474 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 16821420 — Surrogate Endpoint (SUR): Blood pressure
Study 14571610 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 1578874 — Safety Biomarker (SAF): Hyaluronic acid
Study 3905210 — Surrogate Endpoint (SUR): Blood pressure
Study 26576711 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15961004 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29289538 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29289538 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24957073 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 22236405 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 28068560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7662240 — Surrogate Endpoint (SUR): Blood pressure
Study 11798012 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25827430 — Surrogate Endpoint (SUR): Blood pressure
Study 23359520 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23359520 — Surrogate Endpoint (SUR): Blood pressure
Study 14599854 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7570621 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 20419336 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9193837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1358003 — Surrogate Endpoint (SUR): Blood pressure
Study 2997306 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30887250 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30887250 — Predictive Biomarker (PRD): NOTCH3 mRNA
Genes: NOTCH3
Study 30887250 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31119173 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 25008546 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 14722542 — Surrogate Endpoint (SUR): Blood pressure
Study 3400079 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30821829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21838092 — Surrogate Endpoint (SUR): Blood pressure
Study 25966339 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25966339 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22358273 — Surrogate Endpoint (SUR): Blood pressure
Study 12708976 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 10743796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25243534 — Surrogate Endpoint (SUR): Serum creatinine
Study 17485593 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 31129907 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23448618 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 16799034 — Surrogate Endpoint (SUR): Blood pressure
Study 31174576 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20950385 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7677387 — Surrogate Endpoint (SUR): Blood pressure
Study 31116313 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31116313 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31116313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11477342 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9667249 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3289507 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25947167 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25947167 — Safety Biomarker (SAF): BDNF
Study 17806038 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15448117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12061999 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8591941 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 195328 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 28291262 — Predictive Biomarker (PRD): SLC12A2 mRNA
Genes: SLC12A2; NKCC1
Study 23668330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23668330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23668330 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 23668330 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21078615 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11783142 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28880941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12200522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12200522 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 7622767 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28233921 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30499637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26051510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17873500 — Surrogate Endpoint (SUR): Blood pressure
Study 31736381 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 31736381 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 23507227 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 19338157 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19338157 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27312565 — Surrogate Endpoint (SUR): Blood pressure
Study 25811847 — Surrogate Endpoint (SUR): Blood pressure
Study 23580602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11688589 — Surrogate Endpoint (SUR): Blood pressure
Study 30656180 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 28450138 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 12483404 — Surrogate Endpoint (SUR): Serum potassium
Study 1555463 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3886401 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20409752 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 20409752 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 31340116 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29067756 — Surrogate Endpoint (SUR): Blood pressure
Study 25073269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22822562 — Surrogate Endpoint (SUR): Blood pressure
Study 22822562 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8137684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8137684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8137684 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 19390751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15120716 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 1645634 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 1645634 — Surrogate Endpoint (SUR): Blood pressure
Study 18517168 — Surrogate Endpoint (SUR): Blood pressure
Study 10981082 — Surrogate Endpoint (SUR): Blood pressure
Study 10981082 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25719988 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 22993101 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25327884 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 11518451 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9489937 — Surrogate Endpoint (SUR): Blood pressure
Study 28794291 — Surrogate Endpoint (SUR): Serum uric acid
Study 28794291 — Surrogate Endpoint (SUR): Serum creatinine
Study 23094638 — Surrogate Endpoint (SUR): Blood pressure
Study 17182297 — Surrogate Endpoint (SUR): Bone mineral density
Study 12394199 — Surrogate Endpoint (SUR): Serum sodium
Study 26109257 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 11049921 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 10800070 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8695127 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30419828 — Surrogate Endpoint (SUR): Blood pressure
Study 30232708 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 24285336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17633360 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17633360 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17633360 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16075346 — Predictive Biomarker (PRD): SYNM mRNA
Genes: SYNM; DMN; KIAA0353; SYN
Study 31326304 — Surrogate Endpoint (SUR): Serum testosterone
Study 26051738 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7869013 — Surrogate Endpoint (SUR): Blood pressure
Study 16386812 — Predictive Biomarker (PRD): PARP9 mRNA
Genes: PARP9; BAL; BAL1
Study 14703598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14703598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14703598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14703598 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10716520 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6829944 — Surrogate Endpoint (SUR): Blood pressure
Study 31860965 — Surrogate Endpoint (SUR): Blood pressure
Study 27418682 — Surrogate Endpoint (SUR): Blood pressure
Study 20233176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16421163 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29143290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9419047 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 9419047 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 8272248 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 3525270 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21972404 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21972404 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 25418873 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18317068 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12808176 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 12808176 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 10475286 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10475286 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11981362 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10420097 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 2043500 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 2043500 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 2043500 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 31096925 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 28697991 — Safety Biomarker (SAF): IL-6 and IL-10
Study 18193497 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 1422321 — Surrogate Endpoint (SUR): Bone mineral density
Study 4045362 — Surrogate Endpoint (SUR): Blood pressure
Study 29675680 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29675680 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 29675680 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 29675680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29675680 — Predictive Biomarker (PRD): Hormone receptor
Study 29200984 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11128679 — Surrogate Endpoint (SUR): Serum uric acid
Study 1459356 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23860287 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 6156364 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31432556 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 31432556 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31432556 — Surrogate Endpoint (SUR): Blood pressure
Study 30207136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30207136 — Safety Biomarker (SAF): Reactive oxygen species
Study 30207136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23502220 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 21849374 — Surrogate Endpoint (SUR): Blood pressure
Study 8091321 — Surrogate Endpoint (SUR): Blood pressure
Study 21651652 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 21651652 — Surrogate Endpoint (SUR): Bone mineral density
Study 19793357 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19793357 — Surrogate Endpoint (SUR): Blood pressure
Study 10693916 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18492534 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31837382 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31837382 — Predictive Biomarker (PRD): MYO1G mRNA
Genes: MYO1G; HA2
Study 24423311 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17598014 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 12066012 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study 9792371 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27571420 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 26048780 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26048780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2