TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02372864 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00265707 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04067882 — Predictive Biomarker (PRD): SAP30 mRNA
Genes: SAP30
Study NCT04067882 — Predictive Biomarker (PRD): UHRF1 mRNA
Genes: UHRF1; ICBP90; NP95; RNF106
Study NCT04067882 — Predictive Biomarker (PRD): PPP1CB mRNA
Genes: PPP1CB
Study NCT04067882 — Predictive Biomarker (PRD): SLFN11 mRNA
Genes: SLFN11
Study NCT04067882 — Predictive Biomarker (PRD): RECQL mRNA
Genes: RECQL; RECQ1; RECQL1
Study NCT04067882 — Predictive Biomarker (PRD): TRPC1 mRNA
Genes: TRPC1; TRP1
Study NCT04067882 — Predictive Biomarker (PRD): DNAH6 mRNA
Genes: DNAH6; DNAHC6; DNHL1; HL2; KIAA1697
Study NCT04067882 — Predictive Biomarker (PRD): GNL3L mRNA
Genes: GNL3L
Study NCT04067882 — Predictive Biomarker (PRD): SLC36A2 mRNA
Genes: SLC36A2; PAT2; TRAMD1
Study NCT04067882 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT04067882 — Predictive Biomarker (PRD): PUS7L mRNA
Genes: PUS7L
Study NCT04067882 — Predictive Biomarker (PRD): CCDC89 mRNA
Genes: CCDC89; BOIP
Study NCT04067882 — Predictive Biomarker (PRD): PLEKHG1 mRNA
Genes: PLEKHG1; KIAA1209
Study NCT04067882 — Predictive Biomarker (PRD): FAM111B mRNA
Genes: FAM111B; CANP
Study NCT04067882 — Predictive Biomarker (PRD): RPRD2 mRNA
Genes: RPRD2; KIAA0460; HSPC099
Study NCT04160533 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00341055 — Surrogate Endpoint (SUR): Hematologic response
Study NCT01042678 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01896037 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01896037 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02482363 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01270581 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study NCT01723657 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00003148 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00174616 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01183403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02243969 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02514174 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02514174 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04529915 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02210923 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01222624 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT03274219 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03299153 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01370603 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00304239 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT02759497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02154529 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03006172 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT00640861 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT01515878 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04344548 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study NCT04344548 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT04344548 — Predictive Biomarker (PRD): KLRC1 mRNA
Genes: KLRC1; NKG2A
Study NCT01997853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00001765 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04560881 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04552613 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00306189 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01306019 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01306019 — Predictive Biomarker (PRD): LMO2 mRNA
Genes: LMO2; RBTN2; RBTNL1; RHOM2; TTG2
Study NCT01306019 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01052376 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT01628705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01628705 — Predictive Biomarker (PRD): TNFA mRNA
Genes: TNF; TNFA; TNFSF2
Study NCT03431766 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study NCT03029442 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04485650 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03608683 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01078662 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT01078662 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03363659 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT01858376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02679534 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01286727 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT06620159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02409082 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02495831 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT01134393 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02829255 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01669265 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT01669265 — Predictive Biomarker (PRD): TTL mRNA
Genes: TTL
Study NCT01409434 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01409434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03804515 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03804515 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00892190 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study NCT02292810 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT03804996 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02898870 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01596283 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01614977 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT01743300 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00140257 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04487210 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03046953 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02924233 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02922218 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02922218 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT01349088 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01349088 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04402918 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00240682 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03344367 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03407859 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT01252381 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT02520830 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00224705 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study NCT00615108 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00003759 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00003759 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study NCT02494921 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02029001 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT02029001 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study NCT02029001 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study NCT02321501 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01123460 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04033172 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04033172 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04033172 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04033172 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study NCT00553202 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01596374 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study NCT01596374 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00594048 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01578707 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04478981 — Predictive Biomarker (PRD): SELENON mRNA
Genes: SELENON; SELN; SEPN1
Study NCT04478981 — Predictive Biomarker (PRD): LAMA2 mRNA
Genes: LAMA2; LAMM
Study NCT02865694 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT02865694 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00709657 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00709657 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04145440 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT02650635 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study NCT00498953 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00569465 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00569465 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT00569465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00569465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00569465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04371250 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01393236 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT00892398 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00892398 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01387620 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04040010 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study NCT04040010 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03722069 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01757327 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01757327 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01757327 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01950169 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02758314 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02758314 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01739309 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02806245 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT03928158 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02593305 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03969732 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03969732 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04435587 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02847975 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study NCT02847975 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study NCT01625377 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02497937 — Predictive Biomarker (PRD): TRPV4 mRNA
Genes: TRPV4; VRL2; VROAC
Study NCT02621736 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT03356158 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03356158 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01828190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01868035 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00199875 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT01420783 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT01672008 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02256592 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00492531 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01555320 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00005802 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02824237 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study NCT02399371 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00365222 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT02721641 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06150105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02465645 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT02028819 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01590459 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study NCT02797977 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02797977 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT00767598 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT02472262 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study NCT03583697 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT05269784 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT01508026 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02028364 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03845920 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT04604249 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03681652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04626024 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04626024 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04314167 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04314167 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT01056887 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT02540252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02540252 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT02540252 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT02540252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02540252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01745185 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT05816876 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04606563 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04606563 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00034840 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04151537 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02017678 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01182233 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01519583 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00004533 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03650712 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02506062 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05274373 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02328300 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT02390908 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03464071 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT02994069 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00600795 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study NCT03978884 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00523692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02761460 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01780129 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04069143 — Predictive Biomarker (PRD): LPAR1 mRNA
Genes: LPAR1; EDG2; LPA1
Study NCT02076347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02076347 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02727036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02727036 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00629720 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study NCT00113087 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04402060 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT04945577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04945577 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT04945577 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT03992378 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study NCT03992378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04601584 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01842321 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01254032 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT04495933 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00004307 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT04326829 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05283278 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study NCT00939640 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04205981 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04205981 — Safety Biomarker (SAF): BDNF
Study NCT06747481 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT06747481 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT04557436 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04557436 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT01716390 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT04730687 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT04730687 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT05645861 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04647513 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00092638 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01254331 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00858806 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00858806 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00098956 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study NCT00399620 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT02629549 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT04127409 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02665897 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL