TrialPanorama/TrialPanorama-database huggingface dataset:
Study 14992872 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 6148868 — Surrogate Endpoint (SUR): Blood pressure
Study 30717815 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 21505910 — Surrogate Endpoint (SUR): Bone mineral density
Study 11323536 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 7909525 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9442429 — Surrogate Endpoint (SUR): Probing pocket depth
Study 3339790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26958799 — Surrogate Endpoint (SUR): Blood pressure
Study 23110878 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21612625 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11741555 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7587599 — Monitoring Biomarker (MOI): HBV DNA
Study 31013820 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 9443459 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 9443459 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17329276 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 17329276 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17329276 — Surrogate Endpoint (SUR): Blood pressure
Study 9893219 — Surrogate Endpoint (SUR): Blood pressure
Study 27865949 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27865949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27865949 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23594787 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27594122 — Surrogate Endpoint (SUR): Blood pressure
Study 10434235 — Surrogate Endpoint (SUR): Blood pressure
Study 7607582 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21545485 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9037324 — Surrogate Endpoint (SUR): Blood pressure
Study 22569889 — Surrogate Endpoint (SUR): Blood pressure
Study 20975026 — Surrogate Endpoint (SUR): Blood pressure
Study 12543884 — Surrogate Endpoint (SUR): Blood pressure
Study 12543884 — Surrogate Endpoint (SUR): Serum creatinine
Study 12959304 — Safety Biomarker (SAF): Hypoxanthine-guanine phosphoribosyltransferase
Genes: HPRT1; HPRT
Study 19267711 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19267711 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21092030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21092030 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10472341 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24935879 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 22548646 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 10353069 — Surrogate Endpoint (SUR): Blood pressure
Study 10353069 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30520566 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 30520566 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23040570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20020412 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15053242 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10561336 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31727687 — Surrogate Endpoint (SUR): Serum creatinine
Study 30725411 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 12622925 — Surrogate Endpoint (SUR): Bone mineral density
Study 21974699 — Surrogate Endpoint (SUR): Blood pressure
Study 8346826 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22330753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15990003 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 29898788 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 27840257 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 23598957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23598957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20863432 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20863432 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20863432 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15883431 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9174874 — Surrogate Endpoint (SUR): Blood pressure
Study 22409295 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 24499010 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10583435 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10583435 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8904612 — Surrogate Endpoint (SUR): Blood pressure
Study 1678925 — Surrogate Endpoint (SUR): Blood pressure
Study 28395936 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 23748507 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29849032 — Surrogate Endpoint (SUR): Blood pressure
Study 20520293 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16192477 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16192477 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 17595259 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 17595259 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 17595259 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 14734000 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9810957 — Surrogate Endpoint (SUR): Serum sodium
Study 21651908 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 21651908 — Surrogate Endpoint (SUR): Blood pressure
Study 19288084 — Surrogate Endpoint (SUR): Blood pressure
Study 1881978 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 6578752 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 6578752 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30544716 — Surrogate Endpoint (SUR): Blood pressure
Study 20660224 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 16132323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16132323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24382030 — Surrogate Endpoint (SUR): Blood pressure
Study 24382030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22039165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19131212 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10609905 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16182162 — Surrogate Endpoint (SUR): Blood pressure
Study 7657740 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 31109313 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 28236981 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 23403268 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 23403268 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14510624 — Surrogate Endpoint (SUR): Blood pressure
Study 9074702 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9074702 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9074702 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16482073 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 8426204 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 20026784 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 20026784 — Surrogate Endpoint (SUR): Blood pressure
Study 20026784 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12649629 — Surrogate Endpoint (SUR): Blood pressure
Study 2427840 — Surrogate Endpoint (SUR): Blood pressure
Study 25151098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10385633 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8689882 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8689882 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 8689882 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8689882 — Surrogate Endpoint (SUR): Blood pressure
Study 8689882 — Surrogate Endpoint (SUR): Serum testosterone
Study 30460483 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 2181565 — Surrogate Endpoint (SUR): Blood pressure
Study 28418102 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 9744982 — Surrogate Endpoint (SUR): Bone mineral density
Study 26364276 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 24267039 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24267039 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24267039 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 17996819 — Surrogate Endpoint (SUR): Serum creatinine
Study 17996819 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7657008 — Surrogate Endpoint (SUR): Serum sodium
Study 26401986 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12215958 — Surrogate Endpoint (SUR): Plasma ammonia
Study 23290835 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11357021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11357021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29235659 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29235659 — Surrogate Endpoint (SUR): Blood pressure
Study 25145693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17092242 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 25173199 — Surrogate Endpoint (SUR): Blood pressure
Study 20691689 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 20691689 — Predictive Biomarker (PRD): FGFR4 mRNA
Genes: FGFR4; JTK2; TKF
Study 16538529 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22198242 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10364900 — Predictive Biomarker (PRD): ASPRV1 mRNA
Genes: ASPRV1; SASP
Study 28371942 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 22189672 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 22189672 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 22189672 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22189672 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11795350 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9018407 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23123065 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 23123065 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 26272450 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 16827766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16827766 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8896514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29883839 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 29883839 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29883839 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 29883839 — Predictive Biomarker (PRD): Interleukin 4 receptor alpha
Genes: IL4R; IL4RA; 582J2.1
Study 15875189 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31636243 — Surrogate Endpoint (SUR): Blood pressure
Study 30298411 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 24386911 — Surrogate Endpoint (SUR): Hematologic response
Study 17452505 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17452505 — Surrogate Endpoint (SUR): Blood pressure
Study 15054428 — Safety Biomarker (SAF): Reactive oxygen species
Study 18779281 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12886239 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 12886239 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 8436631 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 17185007 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 17185007 — Safety Biomarker (SAF): BDNF
Study 282082 — Surrogate Endpoint (SUR): Blood pressure
Study 30689258 — Monitoring Biomarker (MOI): HBV DNA
Study 25670362 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25670362 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25670362 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21835287 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9569113 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30884808 — Surrogate Endpoint (SUR): Blood pressure
Study 26417002 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 19122170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24636695 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 12652992 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7968646 — Surrogate Endpoint (SUR): Bone mineral density
Study 12723015 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12723015 — Surrogate Endpoint (SUR): Blood pressure
Study 8438914 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 29856928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15111165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15111165 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18454257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18454257 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18454257 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16911289 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 12821233 — Surrogate Endpoint (SUR): Serum creatinine
Study 1517792 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 28658080 — Surrogate Endpoint (SUR): Blood pressure
Study 9661080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31216961 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 23211042 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7616872 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 7616872 — Surrogate Endpoint (SUR): Bone mineral density
Study 28681535 — Surrogate Endpoint (SUR): Blood pressure
Study 21030499 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15053888 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 2907877 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 2907877 — Surrogate Endpoint (SUR): Serum creatinine
Study 20827028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20827028 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10081544 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7752178 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28838685 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23278283 — Surrogate Endpoint (SUR): Serum creatinine
Study 16459222 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16459222 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16459222 — Surrogate Endpoint (SUR): Blood pressure
Study 4051271 — Surrogate Endpoint (SUR): Blood pressure
Study 20039425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20039425 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 16257877 — Surrogate Endpoint (SUR): Blood pressure
Study 8547961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2180849 — Surrogate Endpoint (SUR): Blood pressure
Study 31126121 — Surrogate Endpoint (SUR): Bone mineral density
Study 26694929 — Surrogate Endpoint (SUR): Blood pressure
Study 15953714 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 8697548 — Surrogate Endpoint (SUR): Blood pressure
Study 12150702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8074068 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2698940 — Surrogate Endpoint (SUR): Blood pressure
Study 25589220 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7046543 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 7046543 — Surrogate Endpoint (SUR): Serum creatinine
Study 31603998 — Surrogate Endpoint (SUR): Bone mineral density
Study 23318347 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 17786707 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 2906874 — Surrogate Endpoint (SUR): Blood pressure
Study 28284557 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 28284557 — Predictive Biomarker (PRD): IKBKG mRNA
Genes: IKBKG; FIP3; NEMO
Study 20803855 — Surrogate Endpoint (SUR): Blood pressure
Study 16253158 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16253158 — Surrogate Endpoint (SUR): Blood pressure
Study 9874863 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 23702931 — Surrogate Endpoint (SUR): Bone mineral density
Study 11806433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11806433 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7519191 — Surrogate Endpoint (SUR): Blood pressure
Study 7519191 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12372669 — Surrogate Endpoint (SUR): Blood pressure
Study 10399796 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 24331774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24331774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12823855 — Surrogate Endpoint (SUR): Bone mineral density
Study 10948785 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20398481 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 11957809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7192146 — Surrogate Endpoint (SUR): Blood pressure
Study 21459942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11267717 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study 2595106 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 4402080 — Surrogate Endpoint (SUR): Blood pressure
Study 26333366 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21876298 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 15051841 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9440482 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11723020 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 3521443 — Surrogate Endpoint (SUR): Blood pressure
Study 3521443 — Surrogate Endpoint (SUR): Serum potassium
Study 3521443 — Surrogate Endpoint (SUR): Serum sodium
Study 20467286 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1599636 — Surrogate Endpoint (SUR): Blood pressure
Study 31039482 — Predictive Biomarker (PRD): HTR2C mRNA
Genes: HTR2C; HTR1C
Study 27687377 — Surrogate Endpoint (SUR): Blood pressure
Study 26198931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20301014 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20301014 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16634903 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 12477710 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12477710 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 12477710 — Surrogate Endpoint (SUR): Blood pressure
Study 31816432 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2