TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10404354 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7013510 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29723001 — Surrogate Endpoint (SUR): Blood pressure
Study 23422754 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19901115 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19901115 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 11079255 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8844228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8844228 — Safety Biomarker (SAF): Interleukin 1
Study 29345398 — Surrogate Endpoint (SUR): Blood pressure
Study 22845895 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 27659126 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27659126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27029553 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 11913610 — Surrogate Endpoint (SUR): Blood pressure
Study 9422174 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2137344 — Surrogate Endpoint (SUR): Blood pressure
Study 6962371 — Surrogate Endpoint (SUR): Blood pressure
Study 29737226 — Surrogate Endpoint (SUR): Blood pressure
Study 21191076 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 21191076 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 16201128 — Predictive Biomarker (PRD): FAT1 mRNA
Genes: FAT1; CDHF7; FAT
Study 16201128 — Predictive Biomarker (PRD): FAT2 mRNA
Genes: FAT2; CDHF8; KIAA0811; MEGF1
Study 30298667 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 27742802 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 27742802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27742802 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 27742802 — Predictive Biomarker (PRD): NRF1 mRNA
Genes: NRF1
Study 27742802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 27742802 — Safety Biomarker (SAF): Cytochrome c
Study 8746201 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 8746201 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8746201 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1675370 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31781230 — Predictive Biomarker (PRD): SBDS mRNA
Genes: SBDS; CGI-97
Study 20337988 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 18034853 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 10099064 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10099064 — Surrogate Endpoint (SUR): Blood pressure
Study 1057909 — Surrogate Endpoint (SUR): Blood pressure
Study 15499298 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11433707 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 10353472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10353472 — Monitoring Biomarker (MOI): Procalcitonin
Study 2213262 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 28580602 — Surrogate Endpoint (SUR): Blood pressure
Study 27559351 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21861032 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 26650380 — Surrogate Endpoint (SUR): Bone mineral density
Study 29442239 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16609019 — Predictive Biomarker (PRD): HOXB13 mRNA
Genes: HOXB13
Study 16609019 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8808722 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29753474 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 29753474 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 29753474 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 26836244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21486162 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 21486162 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15037821 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15037821 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15037821 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31930891 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 29934198 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23884638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20102859 — Surrogate Endpoint (SUR): Blood pressure
Study 18635470 — Surrogate Endpoint (SUR): Blood pressure
Study 10472359 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31401675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31401675 — Safety Biomarker (SAF): IL-6 and IL-10
Study 27586548 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22327091 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 20935080 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20935080 — Surrogate Endpoint (SUR): Blood pressure
Study 11833749 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 10517170 — Predictive Biomarker (PRD): Hormone receptor
Study 12480784 — Surrogate Endpoint (SUR): Blood pressure
Study 2697240 — Surrogate Endpoint (SUR): Blood pressure
Study 27588891 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 16427211 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9402166 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9402166 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24719063 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 22388466 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10653869 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28213188 — Surrogate Endpoint (SUR): Blood pressure
Study 25862833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19726290 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 26627641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 14562564 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 11090726 — Surrogate Endpoint (SUR): Blood pressure
Study 9373242 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9373242 — Surrogate Endpoint (SUR): Blood pressure
Study 18550081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9692843 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8025393 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31786177 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 26259134 — Surrogate Endpoint (SUR): Blood pressure
Study 10680804 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 18794104 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10475719 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 26704170 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15610695 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15610695 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27858112 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 25028999 — Surrogate Endpoint (SUR): Serum testosterone
Study 22072362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20467617 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 3933984 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 18670229 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 10663912 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 1345049 — Surrogate Endpoint (SUR): Blood pressure
Study 7437259 — Surrogate Endpoint (SUR): Blood pressure
Study 21235696 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19491283 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 10474149 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6993252 — Surrogate Endpoint (SUR): Blood pressure
Study 20806430 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 20806430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18821688 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28699628 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 19377437 — Surrogate Endpoint (SUR): Blood pressure
Study 18760145 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 15907416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 10832659 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10832659 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 10832659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10832659 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10832659 — Safety Biomarker (SAF): IL-6 and IL-10
Study 31542245 — Predictive Biomarker (PRD): CDKAL1 mRNA
Genes: CDKAL1
Study 11717611 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 28923291 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25755093 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23824699 — Predictive Biomarker (PRD): Chromosome 5q
Study 19637334 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19637334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18838533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18838533 — Surrogate Endpoint (SUR): Blood pressure
Study 12599047 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27647855 — Surrogate Endpoint (SUR): Serum creatinine
Study 30659987 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30659987 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 30659987 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 7208540 — Surrogate Endpoint (SUR): Blood pressure
Study 31752977 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 31752977 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3485203 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 30488404 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 24378101 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 28043722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28043722 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21714711 — Surrogate Endpoint (SUR): Serum uric acid
Study 21714711 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10945314 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 3811806 — Surrogate Endpoint (SUR): Blood pressure
Study 29443653 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29443653 — Predictive Biomarker (PRD): Hormone receptor
Study 27099924 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 27099924 — Predictive Biomarker (PRD): miR-135a
Study 27099924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27099924 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20378840 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20378840 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15703206 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 11783602 — Surrogate Endpoint (SUR): Blood pressure
Study 11783602 — Safety Biomarker (SAF): 51Cr-EDTA
Study 11783602 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9408691 — Surrogate Endpoint (SUR): Serum creatinine
Study 8381081 — Surrogate Endpoint (SUR): Plasma ammonia
Study 31629852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23890931 — Surrogate Endpoint (SUR): Blood pressure
Study 23890931 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15220698 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7591850 — Surrogate Endpoint (SUR): Serum creatinine
Study 16326376 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31769845 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25451384 — Surrogate Endpoint (SUR): Blood pressure
Study 23211356 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19403844 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17005078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17005078 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17005078 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 3788835 — Surrogate Endpoint (SUR): Blood pressure
Study 30103241 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23945842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23945842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1183355 — Surrogate Endpoint (SUR): Blood pressure
Study 26207902 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 23453090 — Surrogate Endpoint (SUR): Blood pressure
Study 21946848 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 27717126 — Surrogate Endpoint (SUR): Blood pressure
Study 24930512 — Surrogate Endpoint (SUR): Blood pressure
Study 21288052 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 2040933 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30938860 — Predictive Biomarker (PRD): CLDN1 mRNA
Genes: CLDN1; CLD1; SEMP1; UNQ481/PRO944
Study 30938860 — Predictive Biomarker (PRD): MUC12 mRNA
Genes: MUC12; MUC11
Study 30938860 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 25759961 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 25759961 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 7872981 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7872981 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22177808 — Surrogate Endpoint (SUR): Probing pocket depth
Study 20831528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20831528 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18711190 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9861520 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9861520 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23890493 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 21980810 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11531217 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31911667 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 31911667 — Predictive Biomarker (PRD): CREG2 mRNA
Genes: CREG2
Study 31911667 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 31911667 — Predictive Biomarker (PRD): CCBE1 mRNA
Genes: CCBE1; KIAA1983; UNQ1921/PRO4395
Study 31911667 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29465052 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29465052 — Surrogate Endpoint (SUR): Blood pressure
Study 23228348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23228348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8718542 — Surrogate Endpoint (SUR): Bone mineral density
Study 28404769 — Surrogate Endpoint (SUR): Blood pressure
Study 22796902 — Surrogate Endpoint (SUR): Blood pressure
Study 20028945 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17901959 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 11281233 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 11281233 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30658649 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study 30658649 — Predictive Biomarker (PRD): PRSS33 mRNA
Genes: PRSS33
Study 30658649 — Predictive Biomarker (PRD): FCER1A mRNA
Genes: FCER1A; FCE1A
Study 30658649 — Predictive Biomarker (PRD): HRH4 mRNA
Genes: HRH4; GPCR105
Study 30658649 — Predictive Biomarker (PRD): ADORA3 mRNA
Genes: ADORA3
Study 30658649 — Predictive Biomarker (PRD): P2RY14 mRNA
Genes: P2RY14; GPR105; KIAA0001
Study 30658649 — Predictive Biomarker (PRD): ALOX15 mRNA
Genes: ALOX15; LOG15
Study 30658649 — Predictive Biomarker (PRD): OLIG2 mRNA
Genes: OLIG2; BHLHB1; BHLHE19; PRKCBP2; RACK17
Study 30658649 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 19691834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19691834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17088909 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 17088909 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9131280 — Surrogate Endpoint (SUR): Blood pressure
Study 26874511 — Surrogate Endpoint (SUR): Blood pressure
Study 26874511 — Surrogate Endpoint (SUR): Serum creatinine
Study 26874511 — Surrogate Endpoint (SUR): Serum potassium
Study 19967558 — Surrogate Endpoint (SUR): Bone mineral density
Study 1058422 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 30390361 — Surrogate Endpoint (SUR): Blood pressure
Study 27320184 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27320184 — Surrogate Endpoint (SUR): Blood pressure
Study 9196144 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24933196 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24933196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24933196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24933196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18008221 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 7933707 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 2012295 — Surrogate Endpoint (SUR): Blood pressure
Study 16765700 — Surrogate Endpoint (SUR): Blood pressure
Study 3222686 — Surrogate Endpoint (SUR): Blood pressure
Study 26083696 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15575343 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15575343 — Surrogate Endpoint (SUR): Blood pressure
Study 18832295 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29979388 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 23646468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23646468 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15074089 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30446275 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30446275 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 29558756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29558756 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12030915 — Surrogate Endpoint (SUR): Serum testosterone
Study 18580406 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 18580406 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study 10805048 — Surrogate Endpoint (SUR): Blood pressure
Study 9894580 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 9894580 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24481688 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 29476810 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 24742970 — Safety Biomarker (SAF): Urinary total protein