TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24527605 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22613427 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8548058 — Predictive Biomarker (PRD): GCSAM mRNA
Genes: GCSAM; GAL; GCET2
Study 1978443 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 30683457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30683457 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22172725 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 12002492 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 2192405 — Surrogate Endpoint (SUR): Blood pressure
Study 8210915 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22909147 — Surrogate Endpoint (SUR): Blood pressure
Study 15994852 — Surrogate Endpoint (SUR): Blood pressure
Study 14616169 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 10805221 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10805221 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16231758 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16231758 — Surrogate Endpoint (SUR): Blood pressure
Study 10199878 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30659073 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 9272406 — Surrogate Endpoint (SUR): Blood pressure
Study 3069882 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 12732600 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10976551 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10976551 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10976551 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 10976551 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10976551 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25842933 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 16356801 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10715368 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2026464 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 2026464 — Surrogate Endpoint (SUR): Blood pressure
Study 24152421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26864436 — Predictive Biomarker (PRD): PLIN5 mRNA
Genes: PLIN5; LSDP5; OXPAT; PAT-1
Study 22517217 — Surrogate Endpoint (SUR): Blood pressure
Study 22517217 — Surrogate Endpoint (SUR): Serum creatinine
Study 8839902 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1401309 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1401309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26994949 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 12151999 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2184794 — Surrogate Endpoint (SUR): Blood pressure
Study 9610787 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 8387254 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8387254 — Surrogate Endpoint (SUR): Blood pressure
Study 21034597 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3698513 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22057309 — Surrogate Endpoint (SUR): Blood pressure
Study 11078175 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11078175 — Surrogate Endpoint (SUR): Blood pressure
Study 12803585 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 8866410 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30475942 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30521699 — Surrogate Endpoint (SUR): Blood pressure
Study 25919474 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 23682163 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23682163 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 19343062 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28870848 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 24552852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24552852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24552852 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16857655 — Surrogate Endpoint (SUR): Blood pressure
Study 16857655 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16857655 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31648006 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28894068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28894068 — Surrogate Endpoint (SUR): Blood pressure
Study 27346964 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31411383 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26351350 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21943352 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21943352 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 21943352 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 19782784 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8862639 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12950328 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1442656 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27240158 — Surrogate Endpoint (SUR): Blood pressure
Study 18155993 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18155993 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16362853 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 12431318 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10226853 — Surrogate Endpoint (SUR): Blood pressure
Study 6617066 — Surrogate Endpoint (SUR): Blood pressure
Study 21127883 — Safety Biomarker (SAF): Reactive oxygen species
Study 11724204 — Surrogate Endpoint (SUR): Blood pressure
Study 9425876 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 30957736 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 25710288 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15013268 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10374272 — Surrogate Endpoint (SUR): Blood pressure
Study 23444203 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 14699304 — Surrogate Endpoint (SUR): Bone mineral density
Study 26129915 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12531808 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8969721 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8969721 — Surrogate Endpoint (SUR): Blood pressure
Study 6391658 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 22238398 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 389175 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 25769083 — Surrogate Endpoint (SUR): Bone mineral density
Study 21637031 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21111980 — Surrogate Endpoint (SUR): Serum creatinine
Study 21111980 — Surrogate Endpoint (SUR): Serum potassium
Study 10762510 — Predictive Biomarker (PRD): FCGR2A
Genes: CD32; CD32A; IGFR2; CDw32; Fc-gamma-RIIa; FcgammaRIIa
Study 12297477 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18299686 — Surrogate Endpoint (SUR): Serum creatinine
Study 25792830 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25792830 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7542819 — Surrogate Endpoint (SUR): Blood pressure
Study 26331434 — Surrogate Endpoint (SUR): Blood pressure
Study 15109503 — Surrogate Endpoint (SUR): Blood pressure
Study 11313669 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25943647 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 25089513 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 10791109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10791109 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10791109 — Safety Biomarker (SAF): IL-6 and IL-10
Study 20472116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 7560238 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26368562 — Surrogate Endpoint (SUR): Blood pressure
Study 23418922 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 20580779 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20580779 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8046781 — Surrogate Endpoint (SUR): Blood pressure
Study 8046781 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20423740 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20423740 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20423740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20423740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28911684 — Surrogate Endpoint (SUR): Blood pressure
Study 28911684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26315684 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11253418 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7880151 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 7880151 — Surrogate Endpoint (SUR): Blood pressure
Study 31026118 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31026118 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31026118 — Predictive Biomarker (PRD): Hormone receptor
Study 27771276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28871021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28871021 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9607830 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26044933 — Surrogate Endpoint (SUR): Serum sodium
Study 29544870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27353607 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10409572 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30102686 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29282360 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16140230 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10445599 — Safety Biomarker (SAF): Reactive oxygen species
Study 19667111 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 19667111 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 9431857 — Surrogate Endpoint (SUR): Blood pressure
Study 8099804 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8099804 — Surrogate Endpoint (SUR): Blood pressure
Study 30361237 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 30361237 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 23899930 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23899930 — Surrogate Endpoint (SUR): Blood pressure
Study 19423515 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11744466 — Surrogate Endpoint (SUR): Blood pressure
Study 29878382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29878382 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 22508366 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20634300 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1416418 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 3933317 — Surrogate Endpoint (SUR): Blood pressure
Study 19477351 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16902840 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 16902840 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11405326 — Surrogate Endpoint (SUR): Bone mineral density
Study 15855014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15855014 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10616257 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 7431199 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 31870417 — Surrogate Endpoint (SUR): Serum creatinine
Study 23371492 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 19735771 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 25212601 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 19462544 — Surrogate Endpoint (SUR): Blood pressure
Study 24461313 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24461313 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22012469 — Safety Biomarker (SAF): Hyaluronic acid
Study 11894974 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11407439 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 11407439 — Safety Biomarker (SAF): DRD2
Study 9510490 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9510490 — Surrogate Endpoint (SUR): Plasma testosterone level
Study 9510490 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7812682 — Predictive Biomarker (PRD): CEACAM6 mRNA
Genes: CEACAM6; NCA
Study 14978593 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 9732910 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8151317 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 8151317 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8151317 — Predictive Biomarker (PRD): DUSP3 mRNA
Genes: DUSP3; VHR
Study 3047215 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 19225038 — Surrogate Endpoint (SUR): Blood pressure
Study 16988008 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14682408 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8061853 — Surrogate Endpoint (SUR): Blood pressure
Study 24006669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19153649 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19153649 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16384626 — Predictive Biomarker (PRD): PIN1 mRNA
Genes: PIN1
Study 31708447 — Surrogate Endpoint (SUR): Blood pressure
Study 22896670 — Predictive Biomarker (PRD): RXRA mRNA
Genes: RXRA; NR2B1
Study 22896670 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 20668372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10418851 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17023289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17023289 — Surrogate Endpoint (SUR): Serum creatinine
Study 25246609 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 27436422 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 26420196 — Surrogate Endpoint (SUR): Blood pressure
Study 9446004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2963213 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31771940 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 29288162 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 20386017 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20386017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22888768 — Surrogate Endpoint (SUR): Blood pressure
Study 8941061 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 27893676 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27893676 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25300112 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21328517 — Surrogate Endpoint (SUR): Bone mineral density
Study 12779109 — Surrogate Endpoint (SUR): Blood pressure
Study 18925524 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 16612068 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 6609243 — Surrogate Endpoint (SUR): Blood pressure
Study 30991399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12062222 — Surrogate Endpoint (SUR): Blood pressure
Study 31746327 — Surrogate Endpoint (SUR): Serum calcium
Study 7505970 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19819724 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 19819724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1400877 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 1400877 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1400877 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25441591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25441591 — Surrogate Endpoint (SUR): Blood pressure
Study 16430721 — Surrogate Endpoint (SUR): Blood pressure
Study 16430721 — Surrogate Endpoint (SUR): Serum creatinine
Study 25153486 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 18719669 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 8747374 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22700717 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19962941 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 19962941 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 17377856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24411819 — Predictive Biomarker (PRD): FANCE mRNA
Genes: FANCE; FACE
Study 29066452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29066452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19777213 — Surrogate Endpoint (SUR): Blood pressure
Study 17580150 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 15446319 — Surrogate Endpoint (SUR): Serum creatinine
Study 24867603 — Surrogate Endpoint (SUR): Serum testosterone
Study 15468370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15468370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15468370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31673103 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10695822 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20600604 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 1927942 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27587605 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 8609242 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8609242 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 31010126 — Predictive Biomarker (PRD): TMPRSS6 mRNA
Genes: TMPRSS6; UNQ354/PRO618
Study 29098257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23602881 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23602881 — Safety Biomarker (SAF): BDNF
Study 19589139 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 26807536 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 12667600 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6372934 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22031510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22031510 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 18519174 — Predictive Biomarker (PRD): RASL12 mRNA
Genes: RASL12; RIS
Study 31593559 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1