TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10613613 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10613613 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7778068 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2140250 — Surrogate Endpoint (SUR): Blood pressure
Study 31565913 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23433601 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 23433601 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 23433601 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 23433601 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23433601 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9657576 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2764287 — Surrogate Endpoint (SUR): Blood pressure
Study 31556542 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 22249412 — Surrogate Endpoint (SUR): Blood pressure
Study 17475891 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17475891 — Predictive Biomarker (PRD): FCGR2A
Genes: CD32; CD32A; IGFR2; CDw32; Fc-gamma-RIIa; FcgammaRIIa
Study 17475891 — Predictive Biomarker (PRD): FCGR3A
Genes: CD16; CD16a; FcgammaRIIIa; FcGRIIIA
Study 15755868 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20092962 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study 31302043 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27094610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25458329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25458329 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25458329 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17466917 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 12547241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7662901 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7662901 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 30670282 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 27881395 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27881395 — Surrogate Endpoint (SUR): Blood pressure
Study 8178250 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28971609 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24250291 — Surrogate Endpoint (SUR): Blood pressure
Study 18440315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16531926 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 10907942 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1356922 — Surrogate Endpoint (SUR): Blood pressure
Study 22686073 — Surrogate Endpoint (SUR): Serum creatinine
Study 16267763 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10343521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31929136 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24104790 — Surrogate Endpoint (SUR): Blood pressure
Study 21221853 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21221853 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18413818 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 9828818 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 24961184 — Surrogate Endpoint (SUR): Blood pressure
Study 21947316 — Surrogate Endpoint (SUR): Blood pressure
Study 15222054 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15046691 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23325325 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 19570991 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18181332 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26242295 — Surrogate Endpoint (SUR): Blood pressure
Study 15940132 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15940132 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18591750 — Surrogate Endpoint (SUR): Bone mineral density
Study 16616745 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 30063488 — Surrogate Endpoint (SUR): Blood pressure
Study 15895328 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 1611017 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27349575 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 27349575 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22791755 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 22791755 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 22791755 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 22791755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22791755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15848573 — Surrogate Endpoint (SUR): Serum creatinine
Study 25091553 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 22553251 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17623016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7789138 — Predictive Biomarker (PRD): RCOR1 mRNA
Genes: RCOR1; KIAA0071; RCOR
Study 31332700 — Surrogate Endpoint (SUR): Serum creatinine
Study 19593146 — Surrogate Endpoint (SUR): Blood pressure
Study 12625607 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 27434611 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 21251363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11338008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11338008 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18665117 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29454255 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 26855018 — Surrogate Endpoint (SUR): Blood pressure
Study 20417856 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22512265 — Surrogate Endpoint (SUR): Blood pressure
Study 22512265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22512265 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20622608 — Surrogate Endpoint (SUR): Blood pressure
Study 12932604 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12932604 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23817631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31995035 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10021877 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17093898 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10484048 — Surrogate Endpoint (SUR): Blood pressure
Study 25693050 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16815489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16815489 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9372661 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1284155 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 31393834 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 27163301 — Surrogate Endpoint (SUR): Blood pressure
Study 24616451 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 24616451 — Predictive Biomarker (PRD): MGLL mRNA
Genes: MGLL
Study 16236738 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12166560 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12166560 — Surrogate Endpoint (SUR): Serum testosterone
Study 11286323 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25895202 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25895202 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 25895202 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20179914 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11122135 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11122135 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7717832 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 7314025 — Surrogate Endpoint (SUR): Blood pressure
Study 30831045 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 17768297 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 3236319 — Surrogate Endpoint (SUR): Blood pressure
Study 26335129 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 8087826 — Surrogate Endpoint (SUR): Blood pressure
Study 2969906 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25345681 — Surrogate Endpoint (SUR): Blood pressure
Study 18623908 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 18623908 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12640507 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12640507 — Surrogate Endpoint (SUR): Blood pressure
Study 31556165 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 11465336 — Surrogate Endpoint (SUR): Blood pressure
Study 24901857 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 23104122 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 18926059 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27310949 — Surrogate Endpoint (SUR): Serum uric acid
Study 27310949 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9786602 — Surrogate Endpoint (SUR): Blood pressure
Study 9786602 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8632572 — Surrogate Endpoint (SUR): Serum testosterone
Study 30633722 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 22044557 — Surrogate Endpoint (SUR): Blood pressure
Study 22044557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24077371 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24077371 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22302233 — Surrogate Endpoint (SUR): Blood pressure
Study 12835430 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 6693788 — Surrogate Endpoint (SUR): Serum creatinine
Study 29395236 — Surrogate Endpoint (SUR): Blood pressure
Study 12242455 — Surrogate Endpoint (SUR): Blood pressure
Study 30672255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30672255 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16547688 — Surrogate Endpoint (SUR): Bone mineral density
Study 1358037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1358037 — Safety Biomarker (SAF): Interleukin 1
Study 1358037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3882619 — Surrogate Endpoint (SUR): Blood pressure
Study 30994776 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 30994776 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26990892 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 21048963 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 18387931 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18387931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16794097 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14648127 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 29016474 — Surrogate Endpoint (SUR): Blood pressure
Study 25214548 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 16052297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16052297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10366112 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 8808186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8808186 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 20195641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20195641 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 15591328 — Surrogate Endpoint (SUR): Blood pressure
Study 30897686 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 26482247 — Surrogate Endpoint (SUR): Blood pressure
Study 8878758 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25857366 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25110226 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22479156 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19008494 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19008494 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 9661589 — Surrogate Endpoint (SUR): Bone mineral density
Study 8005183 — Surrogate Endpoint (SUR): Blood pressure
Study 22456329 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22456329 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17200487 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 9724685 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 23602084 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30810079 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 21048706 — Predictive Biomarker (PRD): GCG mRNA
Genes: GCG
Study 21048706 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21048706 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 2231185 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25469451 — Predictive Biomarker (PRD): CES2 mRNA
Genes: CES2; ICE
Study 25469451 — Predictive Biomarker (PRD): USP9X mRNA
Genes: USP9X; DFFRX; FAM; USP9
Study 7686471 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 18055508 — Surrogate Endpoint (SUR): Blood pressure
Study 12564608 — Safety Biomarker (SAF): DRD2
Study 1888248 — Surrogate Endpoint (SUR): Blood pressure
Study 23886255 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19854420 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study 14688377 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 14688377 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12221212 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 7587846 — Surrogate Endpoint (SUR): Blood pressure
Study 17481800 — Surrogate Endpoint (SUR): Blood pressure
Study 8187231 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 31563497 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 30817099 — Surrogate Endpoint (SUR): Blood pressure
Study 23621831 — Surrogate Endpoint (SUR): Blood pressure
Study 21566299 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9200197 — Predictive Biomarker (PRD): KCP mRNA
Genes: KCP; CRIM2; KCP1
Study 21246521 — Predictive Biomarker (PRD): INA mRNA
Genes: INA; NEF5
Study 21246521 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 21246521 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 21246521 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 15042673 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29551222 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 29551222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29551222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10881250 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9008256 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9008256 — Surrogate Endpoint (SUR): Blood pressure
Study 27395413 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21387109 — Predictive Biomarker (PRD): TPBG mRNA
Genes: TPBG; 5T4
Study 18250971 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8398588 — Surrogate Endpoint (SUR): Blood pressure
Study 10369612 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8675554 — Surrogate Endpoint (SUR): Bone mineral density
Study 20167668 — Surrogate Endpoint (SUR): Blood pressure
Study 20167668 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28132876 — Surrogate Endpoint (SUR): Blood pressure
Study 25901548 — Surrogate Endpoint (SUR): Blood pressure
Study 17716314 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 15479128 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11398153 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11398153 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3400659 — Surrogate Endpoint (SUR): Bone mineral density
Study 27228299 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27228299 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27228299 — Surrogate Endpoint (SUR): Blood pressure
Study 20511192 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 18455389 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 18455389 — Surrogate Endpoint (SUR): Serum testosterone
Study 15786818 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15786818 — Surrogate Endpoint (SUR): Serum potassium
Study 8573412 — Surrogate Endpoint (SUR): Bone mineral density
Study 8573412 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30602156 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30602156 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30602156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30602156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12542933 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31303099 — Surrogate Endpoint (SUR): Serum creatinine
Study 25216771 — Surrogate Endpoint (SUR): Blood pressure
Study 22027703 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 15266334 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 7920018 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 7920018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7920018 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7920018 — Safety Biomarker (SAF): Interleukin 1
Study 3241121 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25640470 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22029858 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15692117 — Surrogate Endpoint (SUR): Blood pressure
Study 8559495 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 7419011 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7419011 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30776476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30776476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19515536 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 9643531 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8159103 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28416195 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 22584916 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14578411 — Surrogate Endpoint (SUR): Blood pressure
Study 2859183 — Surrogate Endpoint (SUR): Blood pressure
Study 16042022 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 27466224 — Safety Biomarker (SAF): Hyaluronic acid
Study 18844764 — Surrogate Endpoint (SUR): Blood pressure
Study 10545429 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 10545429 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24443618 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17412737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26980471 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18991814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1