TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21527594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21527594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18467280 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 17518666 — Safety Biomarker (SAF): Hyaluronic acid
Study 22911284 — Surrogate Endpoint (SUR): Bone mineral density
Study 8946272 — Surrogate Endpoint (SUR): Blood pressure
Study 8946272 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29516257 — Surrogate Endpoint (SUR): Blood pressure
Study 27484673 — Safety Biomarker (SAF): Cytochrome c
Study 6123343 — Surrogate Endpoint (SUR): Blood pressure
Study 27797683 — Surrogate Endpoint (SUR): Blood pressure
Study 26029855 — Predictive Biomarker (PRD): GNL3 mRNA
Genes: GNL3; E2IG3; NS
Study 26029855 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21442805 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9390588 — Surrogate Endpoint (SUR): Blood pressure
Study 7910722 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7910722 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 14586387 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 14586387 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 9176539 — Surrogate Endpoint (SUR): Blood pressure
Study 29773846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29773846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26581199 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8391072 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25668345 — Surrogate Endpoint (SUR): Blood pressure
Study 16886964 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3299441 — Surrogate Endpoint (SUR): Blood pressure
Study 14594787 — Surrogate Endpoint (SUR): Bone mineral density
Study 8781012 — Surrogate Endpoint (SUR): Blood pressure
Study 1395211 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6347233 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6347233 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 11122299 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 9491847 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26011424 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26011424 — Safety Biomarker (SAF): BDNF
Study 24263115 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28304147 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28028947 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25552038 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15570414 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 15570414 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15570414 — Surrogate Endpoint (SUR): Serum calcium
Study 18760153 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 12821556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12821556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12821556 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8929748 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 84532 — Predictive Biomarker (PRD): CNDP2 mRNA
Genes: CNDP2; CN2; CPGL; HEL-S-13; PEPA
Study 26996196 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11692899 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 29466268 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 19769420 — Surrogate Endpoint (SUR): Blood pressure
Study 23763455 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23763455 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19933744 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19933744 — Predictive Biomarker (PRD): AGBL2 mRNA
Genes: AGBL2; CCP2
Study 18949179 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12632438 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 12632438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29594819 — Safety Biomarker (SAF): IL16
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 21815126 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9277046 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 25903742 — Surrogate Endpoint (SUR): Serum creatinine
Study 21357827 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20037682 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9509952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18413218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31409981 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26936782 — Surrogate Endpoint (SUR): Blood pressure
Study 20828304 — Surrogate Endpoint (SUR): Bone mineral density
Study 15576836 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8273801 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 10499749 — Surrogate Endpoint (SUR): Blood pressure
Study 9030391 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22878451 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22878451 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20805299 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 653509 — Surrogate Endpoint (SUR): Serum calcium
Study 25449654 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23842127 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21968873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16461819 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16461819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11159890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11159890 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11159890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7889644 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study 17884515 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 3026264 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3026264 — Surrogate Endpoint (SUR): Blood pressure
Study 15531004 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29641467 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 24296323 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 24296323 — Surrogate Endpoint (SUR): Blood pressure
Study 27832025 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 23158561 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8067560 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24103632 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24103632 — Safety Biomarker (SAF): BDNF
Study 22364739 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 17659757 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 16374010 — Predictive Biomarker (PRD): ADGRE5 mRNA
Genes: ADGRE5; CD97
Study 16374010 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 9595977 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 26126810 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 26126810 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 26126810 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 23237936 — Surrogate Endpoint (SUR): Serum potassium
Study 23237936 — Surrogate Endpoint (SUR): Serum sodium
Study 21767149 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 19498098 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 11785712 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7707164 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7707164 — Surrogate Endpoint (SUR): Blood pressure
Study 23571515 — Predictive Biomarker (PRD): GAS6 mRNA
Genes: GAS6; AXLLG
Study 23571515 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23571515 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23571515 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21640879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21640879 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9292243 — Surrogate Endpoint (SUR): Blood pressure
Study 9244644 — Surrogate Endpoint (SUR): Blood pressure
Study 31202270 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 28431047 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 26314902 — Surrogate Endpoint (SUR): Blood pressure
Study 23351633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23351633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26986803 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24886378 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 18611339 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12460329 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 12460329 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12460329 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7568792 — Surrogate Endpoint (SUR): Blood pressure
Study 22520542 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 22520542 — Safety Biomarker (SAF): Interleukin 1
Study 22520542 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22520542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9923586 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9923586 — Surrogate Endpoint (SUR): Blood pressure
Study 2784257 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29580871 — Surrogate Endpoint (SUR): Blood pressure
Study 19048842 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 30843767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30843767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25515657 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 11297000 — Surrogate Endpoint (SUR): Blood pressure
Study 8873932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15749623 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7552316 — Predictive Biomarker (PRD): ELF4 mRNA
Genes: ELF4; ELFR; MEF
Study 26513698 — Surrogate Endpoint (SUR): Blood pressure
Study 24410903 — Predictive Biomarker (PRD): GCG mRNA
Genes: GCG
Study 19672601 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 16876249 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16876249 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30465635 — Surrogate Endpoint (SUR): Blood pressure
Study 16264050 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10494875 — Surrogate Endpoint (SUR): Bone mineral density
Study 1773454 — Predictive Biomarker (PRD): KCP mRNA
Genes: KCP; CRIM2; KCP1
Study 15031565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29091516 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 29091516 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 29091516 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 22998461 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 21150855 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 29061128 — Surrogate Endpoint (SUR): Blood pressure
Study 24283931 — Surrogate Endpoint (SUR): Blood pressure
Study 21374690 — Monitoring Biomarker (MOI): HBV DNA
Study 18171701 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8793417 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24472731 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 17332474 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3288957 — Surrogate Endpoint (SUR): Blood pressure
Study 20632490 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 1703608 — Surrogate Endpoint (SUR): Blood pressure
Study 27572248 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 26052984 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19056596 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 19056596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19056596 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19056596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 217894 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23422332 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17086091 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8798310 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31694410 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 23750778 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16875978 — Predictive Biomarker (PRD): NE
Study 16875978 — Surrogate Endpoint (SUR): Blood pressure
Study 30389673 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 24645985 — Surrogate Endpoint (SUR): Blood pressure
Study 12417540 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 12417540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10360655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31586784 — Surrogate Endpoint (SUR): Blood pressure
Study 21794114 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21794114 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29948444 — Surrogate Endpoint (SUR): Blood pressure
Study 25111385 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8873738 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31500524 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31500524 — Surrogate Endpoint (SUR): Blood pressure
Study 19800931 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 1881831 — Surrogate Endpoint (SUR): Blood pressure
Study 20932900 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20932900 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17006439 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9926240 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31520741 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 28039291 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28039291 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28039291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19401880 — Surrogate Endpoint (SUR): Blood pressure
Study 9291856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29431125 — Surrogate Endpoint (SUR): Blood pressure
Study 20830870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20830870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20830870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20830870 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18761242 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18761242 — Surrogate Endpoint (SUR): Serum creatinine
Study 16368820 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12821954 — Surrogate Endpoint (SUR): Blood pressure
Study 28729040 — Surrogate Endpoint (SUR): Blood pressure
Study 11896507 — Surrogate Endpoint (SUR): Blood pressure
Study 9564748 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 8180671 — Surrogate Endpoint (SUR): Blood pressure
Study 29683855 — Surrogate Endpoint (SUR): Bone mineral density
Study 18252784 — Surrogate Endpoint (SUR): Bone mineral density
Study 16368298 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 16368298 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12525717 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 1522692 — Surrogate Endpoint (SUR): Blood pressure
Study 24252035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19332659 — Surrogate Endpoint (SUR): Blood pressure
Study 19332659 — Surrogate Endpoint (SUR): Serum creatinine
Study 9084795 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15926874 — Surrogate Endpoint (SUR): Blood pressure
Study 8589322 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27776269 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 17923015 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 12039485 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 2539403 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2539403 — Surrogate Endpoint (SUR): Serum creatinine
Study 25722382 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 23430455 — Surrogate Endpoint (SUR): Blood pressure
Study 23430455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12200354 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 342625 — Safety Biomarker (SAF): Preexisting antibody
Study 23950585 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11556937 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9623507 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17426086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2393075 — Surrogate Endpoint (SUR): Blood pressure
Study 26714164 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20623180 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17624687 — Surrogate Endpoint (SUR): Blood pressure
Study 24271261 — Predictive Biomarker (PRD): HPX mRNA
Genes: HPX
Study 18771886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18771886 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19412007 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 17242315 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12575591 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9595973 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 7887107 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2463559 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31477164 — Surrogate Endpoint (SUR): Blood pressure
Study 25792638 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24192471 — Surrogate Endpoint (SUR): Blood pressure
Study 9443587 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20073428 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 16359878 — Surrogate Endpoint (SUR): Blood pressure
Study 29315019 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29315019 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12848585 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 10841825 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11068483 — Predictive Biomarker (PRD): TSHR mRNA
Genes: TSHR; LGR3
Study 8817007 — Surrogate Endpoint (SUR): Blood pressure
Study 31663816 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838