TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17993728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17993728 — Safety Biomarker (SAF): Interleukin 1
Study 15379365 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28728744 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25789519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15286543 — Predictive Biomarker (PRD): SERPINF2 mRNA
Genes: SERPINF2; AAP; PLI
Study 25497998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19114376 — Surrogate Endpoint (SUR): Serum creatinine
Study 9207619 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21998053 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21998053 — Surrogate Endpoint (SUR): Blood pressure
Study 10817849 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8911839 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19237895 — Surrogate Endpoint (SUR): Serum creatinine
Study 19237895 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19237895 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11413078 — Surrogate Endpoint (SUR): Blood pressure
Study 24327720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24327720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24327720 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15860853 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15860853 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12475151 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 7635420 — Safety Biomarker (SAF): Interleukin 1
Study 1071698 — Surrogate Endpoint (SUR): Blood pressure
Study 30657576 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30657576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30657576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30657576 — Predictive Biomarker (PRD): VLDLR mRNA
Genes: VLDLR
Study 30657576 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30657576 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30657576 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11759742 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 31449975 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31449975 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 31449975 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 31449975 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28851933 — Predictive Biomarker (PRD): RAB8A mRNA
Genes: RAB8A; MEL; RAB8
Study 28851933 — Surrogate Endpoint (SUR): Blood pressure
Study 19636163 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16784965 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16784965 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31819201 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31819201 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31819201 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28361576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26182387 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 17521776 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 27098971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22041253 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 28711423 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 25809579 — Surrogate Endpoint (SUR): Blood pressure
Study 23650431 — Surrogate Endpoint (SUR): Blood pressure
Study 19595037 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9761517 — Surrogate Endpoint (SUR): Blood pressure
Study 7834862 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20056003 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 20056003 — Surrogate Endpoint (SUR): Bone mineral density
Study 18684793 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29101521 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 22746973 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 10544378 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 31167726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27243803 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 23034262 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8612440 — Surrogate Endpoint (SUR): Blood pressure
Study 28549278 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25546413 — Predictive Biomarker (PRD): SIRT3 mRNA
Genes: SIRT3; SIR2L3
Study 25546413 — Safety Biomarker (SAF): Reactive oxygen species
Study 7035299 — Surrogate Endpoint (SUR): Serum creatinine
Study 22728413 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20670325 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 16238677 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16238677 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16238677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16238677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21863263 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 10440971 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 29789410 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 29789410 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 21173006 — Surrogate Endpoint (SUR): Blood pressure
Study 15868003 — Surrogate Endpoint (SUR): Blood pressure
Study 14506498 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 10584722 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 31567876 — Predictive Biomarker (PRD): MIAT
Study 19464166 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25519680 — Pharmacodynamic Biomarker (PDY): Peripheral myelin protein 22
Genes: PMP22; GAS3
Study 20441458 — Surrogate Endpoint (SUR): Blood pressure
Study 3743194 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30732648 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24053153 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 21387176 — Surrogate Endpoint (SUR): Bone mineral density
Study 15894837 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15894837 — Surrogate Endpoint (SUR): Blood pressure
Study 8506890 — Surrogate Endpoint (SUR): Blood pressure
Study 8506890 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8506890 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8506890 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26442648 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 12127929 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1697824 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30590412 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20122814 — Predictive Biomarker (PRD): MARCKSL1 mRNA
Genes: MARCKSL1; MLP; MRP
Study 20848164 — Surrogate Endpoint (SUR): Blood pressure
Study 7793585 — Surrogate Endpoint (SUR): Serum creatinine
Study 27091540 — Surrogate Endpoint (SUR): Blood pressure
Study 31589177 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 29017158 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 29017158 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17719312 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 17719312 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8805965 — Surrogate Endpoint (SUR): Blood pressure
Study 1625204 — Surrogate Endpoint (SUR): Blood pressure
Study 17936411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3087678 — Surrogate Endpoint (SUR): Blood pressure
Study 11743379 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 30455761 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 30455761 — Surrogate Endpoint (SUR): Blood pressure
Study 24944132 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21095278 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21095278 — Predictive Biomarker (PRD): CPOX mRNA
Genes: CPOX; CPO; CPX
Study 16444031 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2143687 — Predictive Biomarker (PRD): ITGAM mRNA
Genes: ITGAM; CD11B; CR3A
Study 3186777 — Surrogate Endpoint (SUR): Blood pressure
Study 30369297 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 28435054 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23148981 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 31034455 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21257657 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29624476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2044332 — Surrogate Endpoint (SUR): Blood pressure
Study 7016300 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 27683798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20004781 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16613765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10859453 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 8889853 — Surrogate Endpoint (SUR): Bone mineral density
Study 10426171 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10426171 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 90270 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21692283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 29874228 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21054464 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21054464 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 21054464 — Safety Biomarker (SAF): Interleukin 1
Study 9622282 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7933456 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7933456 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7933456 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27515885 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 23489742 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 12911589 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12911589 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12911589 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19731175 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 21865569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19967149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19967149 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11113085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1549966 — Surrogate Endpoint (SUR): Blood pressure
Study 24758073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15964928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15964928 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28379800 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15246890 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15246890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25968578 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 12600864 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10343208 — Surrogate Endpoint (SUR): Blood pressure
Study 1834443 — Surrogate Endpoint (SUR): Blood pressure
Study 18780503 — Surrogate Endpoint (SUR): Blood pressure
Study 30982782 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30982782 — Surrogate Endpoint (SUR): Blood pressure
Study 23390192 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23390192 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19379993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19379993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16924018 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 8828742 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8828742 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 1345900 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28100469 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28100469 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28100469 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11699608 — Surrogate Endpoint (SUR): Blood pressure
Study 9814459 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 9814459 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9814459 — Surrogate Endpoint (SUR): Serum calcium
Study 31507219 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 2994512 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2994512 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27085561 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22967972 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 19087695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19087695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12243636 — Surrogate Endpoint (SUR): Blood pressure
Study 29556866 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 15625351 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 8597874 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24856027 — Surrogate Endpoint (SUR): Serum creatinine
Study 22382482 — Surrogate Endpoint (SUR): Bone mineral density
Study 14960217 — Surrogate Endpoint (SUR): Blood pressure
Study 15603207 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 28419379 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 11423999 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11423999 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8873964 — Surrogate Endpoint (SUR): Bone mineral density
Study 769527 — Surrogate Endpoint (SUR): Blood pressure
Study 26096296 — Predictive Biomarker (PRD): Hormone receptor
Study 11045858 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 30997482 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15056829 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2671449 — Surrogate Endpoint (SUR): Blood pressure
Study 28403644 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28403644 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25415245 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10805050 — Surrogate Endpoint (SUR): Blood pressure
Study 9132505 — Surrogate Endpoint (SUR): Blood pressure
Study 20367516 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 12482559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8446743 — Surrogate Endpoint (SUR): Blood pressure
Study 3011834 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17694505 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 30844812 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 20228401 — Surrogate Endpoint (SUR): Blood pressure
Study 17355281 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 2240675 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2240675 — Surrogate Endpoint (SUR): Blood pressure
Study 10548198 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22857721 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 25029806 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 17721997 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9661596 — Surrogate Endpoint (SUR): Bone mineral density
Study 12359676 — Predictive Biomarker (PRD): NE
Study 27457818 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20413040 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20413040 — Surrogate Endpoint (SUR): Blood pressure
Study 11286371 — Surrogate Endpoint (SUR): Blood pressure
Study 8803961 — Surrogate Endpoint (SUR): Blood pressure
Study 3892676 — Surrogate Endpoint (SUR): Blood pressure
Study 30344180 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31841795 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31841795 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12392588 — Surrogate Endpoint (SUR): Blood pressure
Study 18308753 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 1833682 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1833682 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25225000 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 23249810 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16136646 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 31809985 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31809985 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31809985 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 18543100 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16440357 — Monitoring Biomarker (MOI): HBV DNA
Study 8421182 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8421182 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24989060 — Surrogate Endpoint (SUR): Serum creatinine
Study 24989060 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10229311 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 6574528 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30371190 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23357715 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 1101614 — Surrogate Endpoint (SUR): Blood pressure
Study 15995958 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 15995958 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27225334 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17587389 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17587389 — Surrogate Endpoint (SUR): Blood pressure
Study 7547368 — Surrogate Endpoint (SUR): Blood pressure
Study 7284971 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30740695 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 15897583 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 8452271 — Surrogate Endpoint (SUR): Blood pressure
Study 15716665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25854593 — Surrogate Endpoint (SUR): Sperm parameters
Study 25854593 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 23723410 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 23723410 — Predictive Biomarker (PRD): ROPN1L mRNA
Genes: ROPN1L; ASP; RSPH11