TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29859385 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29859385 — Safety Biomarker (SAF): Interleukin 1
Study 29859385 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24420547 — Surrogate Endpoint (SUR): Blood pressure
Study 16928483 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 21142442 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24073995 — Surrogate Endpoint (SUR): Blood pressure
Study 11779901 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29635951 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 18800457 — Surrogate Endpoint (SUR): Blood pressure
Study 18800457 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18800457 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18800457 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28453838 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 9735661 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25728587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11549430 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 9820373 — Predictive Biomarker (PRD): Microsatellite instability
Study 2845011 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24943283 — Surrogate Endpoint (SUR): Blood pressure
Study 20921347 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 12578870 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12578870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8250364 — Surrogate Endpoint (SUR): Blood pressure
Study 29205049 — Surrogate Endpoint (SUR): Blood pressure
Study 29205049 — Surrogate Endpoint (SUR): Serum creatinine
Study 15309420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25051124 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21715537 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 21715537 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21715537 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21715537 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10881828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10881828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18716298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17719932 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24043395 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 20557937 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17184595 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 30550892 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30550892 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 12354426 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30303923 — Predictive Biomarker (PRD): Hormone receptor
Study 30303923 — Surrogate Endpoint (SUR): Bone mineral density
Study 8842502 — Surrogate Endpoint (SUR): Blood pressure
Study 24084344 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 24084344 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 24084344 — Predictive Biomarker (PRD): EPHX1 mRNA
Genes: EPHX1; EPHX; EPOX
Study 24084344 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 24084344 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 21820130 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19730391 — Surrogate Endpoint (SUR): Blood pressure
Study 27647662 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24076297 — Surrogate Endpoint (SUR): Serum creatinine
Study 28103388 — Predictive Biomarker (PRD): CRABP2 mRNA
Genes: CRABP2
Study 28103388 — Predictive Biomarker (PRD): LORICRIN mRNA
Genes: LORICRIN; LOR; LRN
Study 28103388 — Predictive Biomarker (PRD): KRT4 mRNA
Genes: KRT4; CYK4
Study 23039968 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 11034112 — Surrogate Endpoint (SUR): Blood pressure
Study 9365082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9365082 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31970414 — Predictive Biomarker (PRD): HDAC8 mRNA
Genes: HDAC8; HDACL1; CDA07
Study 31970414 — Predictive Biomarker (PRD): SMAD3 mRNA
Genes: SMAD3; MADH3
Study 31970414 — Predictive Biomarker (PRD): SIRT7 mRNA
Genes: SIRT7; SIR2L7
Study 31970414 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study 10486645 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 10486645 — Surrogate Endpoint (SUR): Blood pressure
Study 8735683 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31990350 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 31990350 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 31990350 — Predictive Biomarker (PRD): TLR1 mRNA
Genes: TLR1; KIAA0012
Study 31990350 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31990350 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7946179 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7946179 — Surrogate Endpoint (SUR): Blood pressure
Study 26314530 — Surrogate Endpoint (SUR): Blood pressure
Study 10370677 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28264692 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28264692 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 28264692 — Surrogate Endpoint (SUR): Blood pressure
Study 23332183 — Safety Biomarker (SAF): Interleukin 1
Study 23332183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23332183 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 3246316 — Surrogate Endpoint (SUR): Blood pressure
Study 29590407 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18077218 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 1328364 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1328364 — Surrogate Endpoint (SUR): Blood pressure
Study 6108817 — Surrogate Endpoint (SUR): Blood pressure
Study 27853163 — Surrogate Endpoint (SUR): Blood pressure
Study 20390272 — Predictive Biomarker (PRD): GDA mRNA
Genes: GDA; KIAA1258
Study 28549665 — Surrogate Endpoint (SUR): Blood pressure
Study 18487628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8840941 — Surrogate Endpoint (SUR): Blood pressure
Study 17959578 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17959578 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29028973 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29028973 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25200399 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 20048183 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18221472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18221472 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16635225 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 2024739 — Surrogate Endpoint (SUR): Blood pressure
Study 30636832 — Surrogate Endpoint (SUR): Blood pressure
Study 29063309 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27743448 — Surrogate Endpoint (SUR): Probing pocket depth
Study 27743448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27743448 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25373733 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25373733 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 22674882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21677123 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21677123 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21677123 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21677123 — Surrogate Endpoint (SUR): Blood pressure
Study 15704045 — Surrogate Endpoint (SUR): Bone mineral density
Study 12036186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12036186 — Surrogate Endpoint (SUR): Blood pressure
Study 31891694 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23470315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23470315 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20932656 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 8256886 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 8256886 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 23897106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23897106 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24721240 — Monitoring Biomarker (MOI): HBV DNA
Study 15894667 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31295009 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26346590 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 26346590 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 24269033 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 24269033 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22702508 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 22702508 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28050914 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 14530912 — Surrogate Endpoint (SUR): Bone mineral density
Study 8330466 — Surrogate Endpoint (SUR): Serum uric acid
Study 20021624 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7341285 — Surrogate Endpoint (SUR): Blood pressure
Study 28865493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28865493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26650562 — Surrogate Endpoint (SUR): Blood pressure
Study 21212911 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1571851 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 31752260 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 31752260 — Predictive Biomarker (PRD): ULK1 mRNA
Genes: ULK1; KIAA0722
Study 31752260 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study 21357805 — Surrogate Endpoint (SUR): Blood pressure
Study 30605397 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30605397 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22964716 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 22964716 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22964716 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 14998852 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 11514369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 11514369 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 11514369 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study 11514369 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 9700472 — Surrogate Endpoint (SUR): Bone mineral density
Study 9700472 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 9700472 — Surrogate Endpoint (SUR): Serum calcium
Study 8077368 — Surrogate Endpoint (SUR): Blood pressure
Study 23219787 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20309015 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20309015 — Predictive Biomarker (PRD): SULT1A1 mRNA
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 20309015 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15390350 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7890014 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10931390 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23771450 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14640465 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14640465 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8383638 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21256606 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20392970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26525102 — Predictive Biomarker (PRD): PLA2G4A mRNA
Genes: PLA2G4A; CPLA2; PLA2G4
Study 26525102 — Predictive Biomarker (PRD): PLA2G6 mRNA
Genes: PLA2G6; PLPLA9
Study 26525102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23674289 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 18413554 — Surrogate Endpoint (SUR): Blood pressure
Study 18413554 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10601051 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 10601051 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23567070 — Surrogate Endpoint (SUR): Bone mineral density
Study 9024171 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 9024171 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 31362299 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30282670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24164001 — Surrogate Endpoint (SUR): Blood pressure
Study 8612412 — Surrogate Endpoint (SUR): Blood pressure
Study 24270198 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 19249429 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 19249429 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 15097437 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30762945 — Surrogate Endpoint (SUR): Blood pressure
Study 30340488 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27806634 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 1953212 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24488700 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 24488700 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24488700 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12398998 — Predictive Biomarker (PRD): DACH1 mRNA
Genes: DACH1; DACH
Study 9534093 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25075773 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25075773 — Surrogate Endpoint (SUR): Serum creatinine
Study 25075773 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25075773 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 17471343 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23799553 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19322744 — Surrogate Endpoint (SUR): Bone mineral density
Study 17911549 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28644114 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 18250972 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 18250972 — Monitoring Biomarker (MOI): HBV DNA
Study 15035763 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1606067 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 1606067 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 30099933 — Surrogate Endpoint (SUR): Blood pressure
Study 20727522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20727522 — Surrogate Endpoint (SUR): Blood pressure
Study 15630488 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 15630488 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12859158 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12859158 — Surrogate Endpoint (SUR): Blood pressure
Study 27718369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26202488 — Surrogate Endpoint (SUR): Bone mineral density
Study 23176888 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11070330 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 28780559 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28780559 — Surrogate Endpoint (SUR): Blood pressure
Study 27883269 — Predictive Biomarker (PRD): LUM mRNA
Genes: LUM; LDC; SLRR2D
Study 26016869 — Surrogate Endpoint (SUR): Blood pressure
Study 26016869 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26016869 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21901330 — Surrogate Endpoint (SUR): Blood pressure
Study 8014294 — Predictive Biomarker (PRD): ADAM8 mRNA
Genes: ADAM8; MS2
Study 29720209 — Surrogate Endpoint (SUR): Blood pressure
Study 26482278 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 7986838 — Surrogate Endpoint (SUR): Blood pressure
Study 3291559 — Surrogate Endpoint (SUR): Blood pressure
Study 31622131 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31622131 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31622131 — Predictive Biomarker (PRD): Hormone receptor
Study 21435876 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 18491311 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11213546 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 11213546 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18036451 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 9893073 — Surrogate Endpoint (SUR): Bone mineral density
Study 28346569 — Surrogate Endpoint (SUR): Serum creatinine
Study 20938670 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11318966 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29698111 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 29698111 — Predictive Biomarker (PRD): ITGAM mRNA
Genes: ITGAM; CD11B; CR3A
Study 29698111 — Predictive Biomarker (PRD): ELANE mRNA
Genes: ELANE; ELA2
Study 29698111 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29698111 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27430267 — Surrogate Endpoint (SUR): Blood pressure
Study 17048434 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8230265 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 8230265 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31950482 — Surrogate Endpoint (SUR): Blood pressure
Study 29122559 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20689074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8649053 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 8649053 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 1960378 — Monitoring Biomarker (MOI): HBV DNA
Study 24717626 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 2913775 — Surrogate Endpoint (SUR): Blood pressure
Study 2913775 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30452928 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 29212477 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29212477 — Surrogate Endpoint (SUR): Blood pressure
Study 21272196 — Surrogate Endpoint (SUR): Blood pressure
Study 10228190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30472236 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21332299 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17338714 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17338714 — Surrogate Endpoint (SUR): Blood pressure
Study 11180995 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell