TrialPanorama/TrialPanorama-database huggingface dataset:
Study 6366151 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27128667 — Surrogate Endpoint (SUR): Blood pressure
Study 20467874 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 20467874 — Safety Biomarker (SAF): BDNF
Study 29031778 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29031778 — Predictive Biomarker (PRD): Hormone receptor
Study 26156156 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 27039236 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20106824 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20106824 — Surrogate Endpoint (SUR): Blood pressure
Study 17394248 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19416224 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19416224 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15693087 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15693087 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15693087 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7665720 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 25494871 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25494871 — Safety Biomarker (SAF): BDNF
Study 15181066 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 2144260 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 11709782 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 11709782 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 11709782 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11709782 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 1643938 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 26933897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26933897 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 17365993 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 7906288 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23331518 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17719763 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11350501 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 11350501 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22038464 — Predictive Biomarker (PRD): PPARGC1B mRNA
Genes: PPARGC1B; PERC; PGC1; PGC1B; PPARGC1
Study 11897207 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9471927 — Surrogate Endpoint (SUR): Bone mineral density
Study 2369475 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25623393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25623393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2215615 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2215615 — Surrogate Endpoint (SUR): Blood pressure
Study 24429536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22664560 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30585832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30585832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30585832 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30585832 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28330649 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26491284 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22045675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 22045675 — Safety Biomarker (SAF): miR-192
Genes: MIR192
Study 8172088 — Surrogate Endpoint (SUR): Serum calcium
Study 2963793 — Surrogate Endpoint (SUR): Blood pressure
Study 23897243 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23897243 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20220045 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 2192406 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 96459 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 19917869 — Predictive Biomarker (PRD): CD3D mRNA
Genes: CD3D; T3D
Study 19917869 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 2198635 — Surrogate Endpoint (SUR): Blood pressure
Study 31155415 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 23642856 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23642856 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17223996 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 30557099 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 17708864 — Surrogate Endpoint (SUR): Bone mineral density
Study 9439556 — Surrogate Endpoint (SUR): Blood pressure
Study 27062851 — Surrogate Endpoint (SUR): Bone mineral density
Study 24739260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3084015 — Surrogate Endpoint (SUR): Bone mineral density
Study 29351885 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 9042663 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 9042663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22230474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20124517 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 1319523 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27006189 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25269900 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 17933438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16277797 — Surrogate Endpoint (SUR): Blood pressure
Study 16277797 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7767538 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 26805529 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 26805529 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Lung surfactant protein D
Genes: SFTPD; COLEC7; PSPD; SFTP4
Study 21880336 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14998944 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16495245 — Monitoring Biomarker (MOI): HBV DNA
Study 8444719 — Surrogate Endpoint (SUR): Blood pressure
Study 3097726 — Surrogate Endpoint (SUR): Blood pressure
Study 30242809 — Predictive Biomarker (PRD): NPSR1 mRNA
Genes: NPSR1; GPR154; GPRA; PGR14
Study 26810768 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22775412 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18779512 — Predictive Biomarker (PRD): CACNA1A mRNA
Genes: CACNA1A; CACH4; CACN3; CACNL1A4
Study 18779512 — Predictive Biomarker (PRD): ATP1A2 mRNA
Genes: ATP1A2; KIAA0778
Study 8722429 — Surrogate Endpoint (SUR): Blood pressure
Study 30209126 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30209126 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15167303 — Surrogate Endpoint (SUR): Bone mineral density
Study 21304095 — Surrogate Endpoint (SUR): Blood pressure
Study 7930717 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 7930717 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24846511 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19501210 — Surrogate Endpoint (SUR): Bone mineral density
Study 16584059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 14667178 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8618436 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24793176 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 22537767 — Surrogate Endpoint (SUR): Blood pressure
Study 20666584 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17346816 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7963710 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7963710 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23584130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23584130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16924028 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 26976420 — Surrogate Endpoint (SUR): Serum creatinine
Study 22921891 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22921891 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22921891 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22921891 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17585311 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 24317968 — Surrogate Endpoint (SUR): Bone mineral density
Study 30325658 — Predictive Biomarker (PRD): CIDEC mRNA
Genes: CIDEC; FSP27
Study 15654716 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 26142578 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 31927748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31927748 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31927748 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16197666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6999291 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6999291 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23642941 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22729015 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12460706 — Surrogate Endpoint (SUR): Blood pressure
Study 8842510 — Surrogate Endpoint (SUR): Blood pressure
Study 1345755 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31115592 — Surrogate Endpoint (SUR): Bone mineral density
Study 16491208 — Surrogate Endpoint (SUR): Blood pressure
Study 11551003 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 3129362 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3129362 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 25262675 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21499725 — Safety Biomarker (SAF): Hyaluronic acid
Study 24962851 — Surrogate Endpoint (SUR): Blood pressure
Study 11524323 — Surrogate Endpoint (SUR): Blood pressure
Study 25966929 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25966929 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24072967 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24072967 — Surrogate Endpoint (SUR): Blood pressure
Study 11720830 — Surrogate Endpoint (SUR): Bone mineral density
Study 27564555 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 23154578 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23154578 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 23154578 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23154578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23154578 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23154578 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19493418 — Surrogate Endpoint (SUR): Blood pressure
Study 11426093 — Surrogate Endpoint (SUR): Blood pressure
Study 7589598 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2141109 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 18045306 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1719655 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1719655 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30561237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30561237 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 25554997 — Surrogate Endpoint (SUR): Blood pressure
Study 19705345 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8783673 — Surrogate Endpoint (SUR): Serum creatinine
Study 25591469 — Surrogate Endpoint (SUR): Serum potassium
Study 25591469 — Surrogate Endpoint (SUR): Blood pressure
Study 22650125 — Surrogate Endpoint (SUR): Blood pressure
Study 19651919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19651919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16840742 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12756385 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12756385 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31924632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31924632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9628521 — Surrogate Endpoint (SUR): Bone mineral density
Study 7511753 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7511753 — Surrogate Endpoint (SUR): Blood pressure
Study 9110123 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30178240 — Surrogate Endpoint (SUR): Blood pressure
Study 27529625 — Surrogate Endpoint (SUR): Blood pressure
Study 11641292 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11641292 — Surrogate Endpoint (SUR): Blood pressure
Study 7978396 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2692407 — Surrogate Endpoint (SUR): Serum calcium
Study 22027717 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19059524 — Surrogate Endpoint (SUR): Bone mineral density
Study 15371986 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15371986 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 7991070 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 7991070 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2663151 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 15752392 — Surrogate Endpoint (SUR): Blood pressure
Study 19807887 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19807887 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 19807887 — Surrogate Endpoint (SUR): Blood pressure
Study 9822268 — Predictive Biomarker (PRD): CCL11 mRNA
Genes: CCL11; SCYA11
Study 21654270 — Surrogate Endpoint (SUR): Serum uric acid
Study 19344008 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24382690 — Monitoring Biomarker (MOI): HBV DNA
Study 8644660 — Surrogate Endpoint (SUR): Blood pressure
Study 11739447 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7684118 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 3320786 — Surrogate Endpoint (SUR): Blood pressure
Study 28566070 — Surrogate Endpoint (SUR): Blood pressure
Study 28566070 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15315724 — Predictive Biomarker (PRD): SLC4A2 mRNA
Genes: SLC4A2; AE2; EPB3L1; HKB3; MPB3L
Study 11167103 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9266276 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8281717 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 29803589 — Surrogate Endpoint (SUR): Blood pressure
Study 12577416 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25463092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22515587 — Safety Biomarker (SAF): Hyaluronic acid
Study 18614926 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18614926 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18614926 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18614926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18614926 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 18614926 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18614926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30126153 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 30126153 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26003334 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16402229 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8122716 — Safety Biomarker (SAF): Hyaluronic acid
Study 28974567 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28974567 — Surrogate Endpoint (SUR): Blood pressure
Study 23972966 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 23972966 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 23972966 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 16508577 — Surrogate Endpoint (SUR): Blood pressure
Study 25683060 — Surrogate Endpoint (SUR): Blood pressure
Study 9280322 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 27072903 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 27072903 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 22639289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22639289 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22639289 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 8171949 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25146070 — Surrogate Endpoint (SUR): Blood pressure
Study 16050413 — Surrogate Endpoint (SUR): Serum calcium
Study 22289106 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 7594124 — Surrogate Endpoint (SUR): Blood pressure
Study 26493588 — Surrogate Endpoint (SUR): Pathological complete response
Study 23800161 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 25222607 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 23176879 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18456678 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18456678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18456678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14871033 — Surrogate Endpoint (SUR): Blood pressure
Study 8922358 — Surrogate Endpoint (SUR): Blood pressure
Study 15235348 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31305011 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 7840317 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21648282 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 21648282 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 19422580 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 9447569 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 8162662 — Surrogate Endpoint (SUR): Blood pressure
Study 8162662 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 3258200 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31856812 — Predictive Biomarker (PRD): Hormone receptor
Study 25418186 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21567262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21567262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11208407 — Surrogate Endpoint (SUR): Blood pressure
Study 19016938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19016938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21245238 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 21245238 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 21138531 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 8972009 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer