TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04267458 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00061815 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00061815 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01595789 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00367562 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03184662 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01245686 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02886507 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02379936 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT04090151 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02483442 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01421667 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00477893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02682485 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT03954275 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study NCT00940069 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01385618 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01385618 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ESR2 mRNA
Genes: ESR2; ESTRB; NR3A2
Study NCT04468412 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04468412 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04771507 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01905826 — Predictive Biomarker (PRD): GATA2 mRNA
Genes: GATA2
Study NCT01231971 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01231971 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01711658 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01711658 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00084396 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00001916 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03176888 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02966665 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study NCT02966665 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT01715194 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00640588 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03920592 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study NCT03920592 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02179268 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03790813 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT02408887 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02697305 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02644369 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00369109 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT03492866 — Predictive Biomarker (PRD): CDSN mRNA
Genes: CDSN
Study NCT01155206 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03615352 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT03559413 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00670046 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT01778907 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT05568017 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study NCT01288443 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02470585 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT01623908 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04251169 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04251169 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04251169 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04251169 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02969759 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03263988 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00862706 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03155113 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02259049 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03901989 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00142636 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT03486574 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT00819156 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00819156 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study NCT00201149 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00418795 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study NCT00540930 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00540930 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01099566 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT01480583 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03032731 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04161560 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01000441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03053440 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03053440 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study NCT04319068 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00140725 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04657887 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03218449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03218449 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT03218449 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03218449 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT05427305 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02394106 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02575924 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study NCT02477813 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT02438007 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03568409 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT00147017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00147017 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01968967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02098837 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00978419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04567979 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01567605 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04741412 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03861234 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04222894 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00930306 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT00930306 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT00930306 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00930306 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00930306 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00930306 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04623489 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00822120 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01630824 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01074359 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT03278873 — Predictive Biomarker (PRD): CNGB3 mRNA
Genes: CNGB3
Study NCT03278873 — Predictive Biomarker (PRD): CNGA3 mRNA
Genes: CNGA3; CNCG3
Study NCT00540241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00925470 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02820233 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02820233 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03046927 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT00736463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04219215 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02143375 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study NCT01232959 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01237496 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00476463 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00327119 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00062855 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04262466 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study NCT00660972 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT01745965 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01745965 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01227213 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03812874 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT04147221 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study NCT03595969 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT01646450 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02291913 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02988193 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04046159 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00902213 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03689946 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01265472 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT00540514 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT00890591 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01579318 — Safety Biomarker (SAF): Interleukin 12
Study NCT00370383 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00370383 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02109575 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02546531 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT04389385 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01503372 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01503372 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04197557 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03592199 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00600275 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02345603 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03617315 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04592185 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT01025128 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04439500 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04056702 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03777254 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01553942 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01553942 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06143709 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03842085 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02426138 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02790281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04555577 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT04290533 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study NCT04075396 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04075396 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02848105 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02848105 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02238769 — Predictive Biomarker (PRD): FECH mRNA
Genes: FECH
Study NCT02940249 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00005249 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00575419 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04354389 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02628106 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04044781 — Predictive Biomarker (PRD): PDE4D mRNA
Genes: PDE4D; DPDE3
Study NCT02586272 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05568082 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01458548 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02588443 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT06571695 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study NCT02402803 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00936416 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00936416 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02132949 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03948295 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03948295 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02915315 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00175812 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT01891370 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03220724 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00232375 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00299572 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04516226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01957332 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01957332 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01957332 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01957332 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04621435 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT00819546 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00819546 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study NCT00272831 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04566952 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT04566952 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04566952 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT05254392 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03206086 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT02262299 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00140400 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01078909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01078909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02417376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02848560 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02724501 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT00121849 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT00732966 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02645942 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00160498 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03329612 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02134262 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04461873 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03024450 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04424459 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study NCT05577624 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02821182 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02322918 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02322918 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02322918 — Safety Biomarker (SAF): BDNF
Study NCT00004978 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00004978 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04094519 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT03018535 — Predictive Biomarker (PRD): PLA2R1 mRNA
Genes: PLA2R1; CLEC13C
Study NCT03018535 — Predictive Biomarker (PRD): THSD7A mRNA
Genes: THSD7A; KIAA0960
Study NCT03018535 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03018535 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study NCT03331419 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02972034 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT02490956 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02638467 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02638467 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT02318368 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00359008 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02728050 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02674464 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00751829 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00342433 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A2 mRNA
Genes: SRD5A2
Study NCT03866005 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03866005 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03159572 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03159572 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT00457119 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study NCT01105975 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01105975 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02824198 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00021567 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04276506 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00783497 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02742233 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01291810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02191891 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00328666 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00853580 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT02108704 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT01761006 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02540824 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT00982644 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01082900 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study NCT04466137 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04466137 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT00004361 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT03317652 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00003593 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study NCT02717468 — Surrogate Endpoint (SUR): Blood pressure