TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31752769 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31752769 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22949147 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22949147 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16113803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16113803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12395212 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 30204921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17621383 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 19933408 — Surrogate Endpoint (SUR): Serum sodium
Study 15588157 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 15588157 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study 15588157 — Safety Biomarker (SAF): MTHFR
Study 2230269 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26458124 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 26458124 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21676368 — Surrogate Endpoint (SUR): Serum creatinine
Study 16940855 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1518260 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6434387 — Surrogate Endpoint (SUR): Blood pressure
Study 22727500 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 19780875 — Monitoring Biomarker (MOI): HBV DNA
Study 11887170 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9516652 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 4278358 — Surrogate Endpoint (SUR): Bacterial count
Study 17524860 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17524860 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 15073670 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11772295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2978875 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 21440948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21440948 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21440948 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21440948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15956126 — Surrogate Endpoint (SUR): Blood pressure
Study 11550967 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29226610 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22985900 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 10687264 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20799973 — Surrogate Endpoint (SUR): Bone mineral density
Study 16273666 — Surrogate Endpoint (SUR): Pathological complete response
Study 10540368 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7573781 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 31993719 — Surrogate Endpoint (SUR): Bone mineral density
Study 30663076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30663076 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23835670 — Predictive Biomarker (PRD): PEX19 mRNA
Genes: PEX19; HK33; PXF; OK/SW-cl.22
Study 19465470 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15148833 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9167210 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9167210 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28012804 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 25047089 — Surrogate Endpoint (SUR): Blood pressure
Study 29861222 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29861222 — Surrogate Endpoint (SUR): Blood pressure
Study 15702239 — Predictive Biomarker (PRD): SEPHS1 mRNA
Genes: SEPHS1; SELD; SPS; SPS1
Study 6857511 — Surrogate Endpoint (SUR): Serum sodium
Study 27826654 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 27826654 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23490255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30901380 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study 30901380 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 27240673 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 27240673 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18457617 — Surrogate Endpoint (SUR): Blood pressure
Study 12437643 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24550191 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 28716786 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26372485 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11473861 — Surrogate Endpoint (SUR): Blood pressure
Study 2968749 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16449027 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 30535217 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 30535217 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20959485 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31672143 — Surrogate Endpoint (SUR): Serum creatinine
Study 27545747 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 17566756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17566756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 31161241 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 31828275 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 18678242 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16297323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16297323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16297323 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 85106 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 17722961 — Monitoring Biomarker (MOI): HBV DNA
Study 26957836 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 26957836 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18060250 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16128945 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 7798579 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7798579 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28679681 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2998786 — Surrogate Endpoint (SUR): Serum potassium
Study 30449521 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 25867139 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24499493 — Surrogate Endpoint (SUR): Blood pressure
Study 20927112 — Surrogate Endpoint (SUR): Blood pressure
Study 17351300 — Surrogate Endpoint (SUR): Hematologic response
Study 9498439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23995469 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 23995469 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 17117016 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14665607 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2942747 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20145273 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 20145273 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 15793191 — Surrogate Endpoint (SUR): Blood pressure
Study 31234639 — Surrogate Endpoint (SUR): Blood pressure
Study 31234639 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8703659 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25253174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25253174 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25253174 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18159905 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study 18159905 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 16129209 — Surrogate Endpoint (SUR): Blood pressure
Study 7734364 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30348124 — Surrogate Endpoint (SUR): Blood pressure
Study 21842159 — Surrogate Endpoint (SUR): Blood pressure
Study 210476 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 16767525 — Surrogate Endpoint (SUR): Bone mineral density
Study 11225965 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20102890 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15999048 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15640477 — Surrogate Endpoint (SUR): Bone mineral density
Study 12047486 — Safety Biomarker (SAF): DRD2
Study 10076615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10076615 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10076615 — Safety Biomarker (SAF): Interleukin 1
Study 31597315 — Surrogate Endpoint (SUR): Serum creatinine
Study 25362220 — Surrogate Endpoint (SUR): Serum creatinine
Study 18625622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30853359 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25722948 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 19276559 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19276559 — Safety Biomarker (SAF): BDNF
Study 11678746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9576161 — Surrogate Endpoint (SUR): Blood pressure
Study 28786197 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study 21055801 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17656129 — Surrogate Endpoint (SUR): Bone mineral density
Study 8556189 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 7137550 — Surrogate Endpoint (SUR): Blood pressure
Study 31685833 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11455143 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25900027 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 25900027 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25900027 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25900027 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 24021959 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 21240530 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 18430318 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31446180 — Safety Biomarker (SAF): Nucleotide triphosphate diphosphatase NUDT15
Genes: NUDT15; MTH2
Study 31446180 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 31446180 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 31446180 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28673741 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 24007717 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 24007717 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 24007717 — Predictive Biomarker (PRD): SCARB1 mRNA
Genes: SCARB1; CD36L1; CLA1
Study 24007717 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study 9296424 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 18028472 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11465654 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2896556 — Surrogate Endpoint (SUR): Blood pressure
Study 24199982 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12653262 — Surrogate Endpoint (SUR): Bone mineral density
Study 12653262 — Surrogate Endpoint (SUR): Serum creatinine
Study 12653262 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 12653262 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29789925 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29789925 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20571894 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20571894 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 20571894 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 6721016 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 31847912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18330516 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 2534405 — Surrogate Endpoint (SUR): Blood pressure
Study 30898819 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 25126957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21272198 — Surrogate Endpoint (SUR): Blood pressure
Study 10848841 — Surrogate Endpoint (SUR): Blood pressure
Study 26495054 — Surrogate Endpoint (SUR): Blood pressure
Study 16410646 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 16410646 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12672279 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8263313 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27022068 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27022068 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27022068 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 27022068 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 27022068 — Predictive Biomarker (PRD): Hormone receptor
Study 2577474 — Surrogate Endpoint (SUR): Serum calcium
Study 18333863 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18333863 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 30959753 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26104939 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11302289 — Surrogate Endpoint (SUR): Blood pressure
Study 23099196 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 10663454 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1906434 — Surrogate Endpoint (SUR): Blood pressure
Study 21058476 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7698136 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7698136 — Surrogate Endpoint (SUR): Blood pressure
Study 699938 — Surrogate Endpoint (SUR): Blood pressure
Study 27716513 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23838912 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9788454 — Surrogate Endpoint (SUR): Serum creatinine
Study 9788454 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25029005 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 18424324 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10520053 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31116355 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31116355 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25014619 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21184622 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 15002062 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9702934 — Surrogate Endpoint (SUR): Blood pressure
Study 9247979 — Surrogate Endpoint (SUR): Blood pressure
Study 1742817 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1742817 — Surrogate Endpoint (SUR): Blood pressure
Study 21073363 — Surrogate Endpoint (SUR): Serum potassium
Study 28333860 — Surrogate Endpoint (SUR): Blood pressure
Study 12214463 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 12214463 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 22104275 — Surrogate Endpoint (SUR): Blood pressure
Study 19834012 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12789169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11288031 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 9107633 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9107633 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 9107633 — Surrogate Endpoint (SUR): Blood pressure
Study 20705220 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26011508 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16580386 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10997687 — Safety Biomarker (SAF): Reactive oxygen species
Study 23471324 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 16915076 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 12675644 — Surrogate Endpoint (SUR): Serum triglycerides
Study 3004797 — Predictive Biomarker (PRD): HM13 mRNA
Genes: HM13; H13; IMP1; PSL3; SPP; MSTP086
Study 12698515 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 28656510 — Surrogate Endpoint (SUR): Serum creatinine
Study 21730076 — Surrogate Endpoint (SUR): Blood pressure
Study 23471041 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study 16421781 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 12925034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12925034 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26346997 — Predictive Biomarker (PRD): RNPC3 mRNA
Genes: RNPC3; KIAA1839; RBM40; RNP; SNRNP65
Study 20037779 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20037779 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20037779 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20037779 — Predictive Biomarker (PRD): Hormone receptor
Study 15726659 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 10365573 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6683566 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 8984127 — Surrogate Endpoint (SUR): Blood pressure
Study 1709240 — Surrogate Endpoint (SUR): Blood pressure
Study 1709240 — Surrogate Endpoint (SUR): Serum uric acid
Study 27177231 — Surrogate Endpoint (SUR): Blood pressure
Study 19918250 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 8932953 — Predictive Biomarker (PRD): TEP1 mRNA
Genes: TEP1; TLP1; TP1
Study 1447385 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 17607078 — Surrogate Endpoint (SUR): Bone mineral density
Study 10096263 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10096263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10096263 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8641320 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8641320 — Surrogate Endpoint (SUR): Blood pressure
Study 22607870 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11960925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26399575 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 2389073 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2389073 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 2389073 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study 2389073 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31265113 — Predictive Biomarker (PRD): CTSB mRNA
Genes: CTSB; CPSB
Study 31265113 — Predictive Biomarker (PRD): VLDLR mRNA
Genes: VLDLR
Study 11691516 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11691516 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11691516 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 11691516 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10205349 — Surrogate Endpoint (SUR): Blood pressure
Study 3280614 — Surrogate Endpoint (SUR): Blood pressure
Study 22633044 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 20932523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16430773 — Surrogate Endpoint (SUR): Bone mineral density