TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12753351 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 18061416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10516931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10516931 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20840194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16197446 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 12629090 — Surrogate Endpoint (SUR): Bone mineral density
Study 2004846 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 27339607 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 19097962 — Safety Biomarker (SAF): Reactive oxygen species
Study 22093888 — Surrogate Endpoint (SUR): Blood pressure
Study 16464383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16464383 — Safety Biomarker (SAF): Interleukin 1
Study 16041153 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12020958 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 30783814 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25182625 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18005494 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10025601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10025601 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 10025601 — Safety Biomarker (SAF): IL-6 and IL-10
Study 7582381 — Surrogate Endpoint (SUR): Serum uric acid
Study 31646650 — Surrogate Endpoint (SUR): Blood pressure
Study 31646650 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31646650 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31646650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31646650 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9422123 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 15115901 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7989942 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3185315 — Surrogate Endpoint (SUR): Blood pressure
Study 29119246 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 29119246 — Predictive Biomarker (PRD): SLC16A4 mRNA
Genes: SLC16A4; MCT4; MCT5
Study 29119246 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 27130911 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 27130911 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27130911 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 27130911 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 27130911 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 27130911 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 27130911 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27130911 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15899030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15899030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31323005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14765699 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 31664909 — Surrogate Endpoint (SUR): Blood pressure
Study 21068707 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16545641 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29956503 — Surrogate Endpoint (SUR): Blood pressure
Study 27097959 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25138574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22142309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22142309 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 22142309 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9825232 — Surrogate Endpoint (SUR): Blood pressure
Study 7666093 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7666093 — Safety Biomarker (SAF): Interleukin 1
Study 28588322 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 23561229 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 21964877 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21964877 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 14514977 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 14514977 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1539732 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11781629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11781629 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11781629 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11781629 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29705992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21569168 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9080303 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9080303 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 9080303 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3812881 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 26987887 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24893214 — Surrogate Endpoint (SUR): Blood pressure
Study 22586483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22586483 — Surrogate Endpoint (SUR): Blood pressure
Study 20828221 — Surrogate Endpoint (SUR): Blood pressure
Study 17420604 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17726611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12166713 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26316026 — Surrogate Endpoint (SUR): Blood pressure
Study 31912860 — Surrogate Endpoint (SUR): Blood pressure
Study 28693563 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 23910795 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 20093975 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 15483465 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9315596 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9315596 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3550455 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 28734822 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23351824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19453893 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 7906386 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2780003 — Surrogate Endpoint (SUR): Blood pressure
Study 7989469 — Surrogate Endpoint (SUR): Bone mineral density
Study 27036112 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 9543445 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25328886 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8698279 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8381935 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 17493509 — Surrogate Endpoint (SUR): Serum creatinine
Study 31474439 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 21732195 — Surrogate Endpoint (SUR): Blood pressure
Study 16498057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20525230 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9884380 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 19786940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19786940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19786940 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 19786940 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19786940 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 7820043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16894240 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 16894240 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 16894240 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 12953340 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7625364 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2506337 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 26101142 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27482610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26643240 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26643240 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26224765 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12743669 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12743669 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12743669 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 21669298 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 15699772 — Surrogate Endpoint (SUR): Serum creatinine
Study 12850361 — Predictive Biomarker (PRD): PRF1
Genes: PFP; P1; HPLH2
Study 10100251 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 19288005 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31948302 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31948302 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25988762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25988762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25988762 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 25988762 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25988762 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23160364 — Surrogate Endpoint (SUR): Blood pressure
Study 1347103 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6734045 — Surrogate Endpoint (SUR): Blood pressure
Study 25889308 — Surrogate Endpoint (SUR): Serum creatinine
Study 15521923 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15521923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31801814 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31801814 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study 21714932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16551889 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16551889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16551889 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16551889 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 14535902 — Surrogate Endpoint (SUR): Blood pressure
Study 28074804 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21372608 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 17135672 — Predictive Biomarker (PRD): LRBA mRNA
Genes: LRBA; BGL; CDC4L; LBA
Study 12707865 — Surrogate Endpoint (SUR): Blood pressure
Study 6486080 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20043083 — Predictive Biomarker (PRD): HPGD mRNA
Genes: HPGD; PGDH1; SDR36C1
Study 26039929 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23943213 — Surrogate Endpoint (SUR): Blood pressure
Study 21288520 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 6195981 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27336154 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22878381 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 12417278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10356076 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1723455 — Surrogate Endpoint (SUR): Blood pressure
Study 31380297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31380297 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25851155 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23380438 — Predictive Biomarker (PRD): SH2D1A mRNA
Genes: SH2D1A; DSHP; SAP
Study 23380438 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 22100606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22100606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22100606 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18597602 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 10329340 — Surrogate Endpoint (SUR): Blood pressure
Study 29462969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12655514 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 12655514 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 12655514 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 2661700 — Surrogate Endpoint (SUR): Blood pressure
Study 30728218 — Surrogate Endpoint (SUR): Blood pressure
Study 17935647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18942523 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10703934 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10703934 — Surrogate Endpoint (SUR): Bone mineral density
Study 30031217 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 22928495 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 26414645 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 16413134 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14643578 — Surrogate Endpoint (SUR): Blood pressure
Study 1608850 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25055880 — Surrogate Endpoint (SUR): Blood pressure
Study 22889512 — Surrogate Endpoint (SUR): Blood pressure
Study 16868056 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16868056 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12620262 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12620262 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12620262 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10856147 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10856147 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27092785 — Predictive Biomarker (PRD): Hormone receptor
Study 20855682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20855682 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20855682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20855682 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 20855682 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31421033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22506794 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15123532 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7648243 — Surrogate Endpoint (SUR): Blood pressure
Study 2523665 — Surrogate Endpoint (SUR): Blood pressure
Study 31350753 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 28165543 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26390898 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7522395 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25405132 — Surrogate Endpoint (SUR): Blood pressure
Study 19083405 — Surrogate Endpoint (SUR): Serum creatinine
Study 19083405 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 9421356 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 3691592 — Surrogate Endpoint (SUR): Blood pressure
Study 18377682 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 16488689 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16488689 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3552358 — Surrogate Endpoint (SUR): Blood pressure
Study 18788218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18788218 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 18788218 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28668422 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 25523287 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 21367884 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21367884 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18510613 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 8180725 — Surrogate Endpoint (SUR): Blood pressure
Study 11238542 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9574640 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2971597 — Predictive Biomarker (PRD): Hormone receptor
Study 2971597 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30077810 — Surrogate Endpoint (SUR): Blood pressure
Study 18477161 — Surrogate Endpoint (SUR): Bone mineral density
Study 18477161 — Surrogate Endpoint (SUR): Serum calcium
Study 16546214 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 23306715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23306715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10680303 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7104913 — Surrogate Endpoint (SUR): Blood pressure
Study 31122926 — Surrogate Endpoint (SUR): Blood pressure
Study 11916777 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 23177514 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19565824 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17014518 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15486373 — Surrogate Endpoint (SUR): Bone mineral density
Study 28374931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28374931 — Safety Biomarker (SAF): Platelet to lymphocyte
Study 17460178 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17460178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10893282 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34