TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03464981 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03547999 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01168440 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT01214941 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01214941 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03846219 — Predictive Biomarker (PRD): DHODH mRNA
Genes: DHODH
Study NCT03283618 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02200575 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04698486 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04086459 — Safety Biomarker (SAF): DRD2
Study NCT00754039 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02839460 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study NCT01117441 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study NCT01117441 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT01441414 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study NCT01441414 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study NCT02902315 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02902315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04339972 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study NCT03123055 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT02580071 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study NCT03615534 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04318418 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04318418 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT00327132 — Predictive Biomarker (PRD): CYP2C18 mRNA
Genes: CYP2C18
Study NCT04462757 — Safety Biomarker (SAF): Interleukin 1
Study NCT01035307 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01035307 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT01319370 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT02659228 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT04078542 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00736788 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02508207 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02508207 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study NCT02371252 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03066076 — Predictive Biomarker (PRD): TSHR mRNA
Genes: TSHR; LGR3
Study NCT03066076 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01051752 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT01186419 — Predictive Biomarker (PRD): Liver iron
Study NCT01882790 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04072185 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01810549 — Safety Biomarker (SAF): Interleukin 1
Study NCT00514917 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT03556176 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03556176 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study NCT04479384 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00999076 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT02868775 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT00819195 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT00536614 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03878459 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04049565 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT04049565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04197986 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT01408498 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02186067 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02016508 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00311805 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02663440 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01799278 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT02993458 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01767389 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00006515 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03556748 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00002718 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00002718 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00330096 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01258855 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01258855 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00382070 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00879359 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00879359 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study NCT00879359 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01850940 — Surrogate Endpoint (SUR): Serum sodium
Study NCT04045626 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT03225937 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01648829 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01648829 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00739570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00739570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03149224 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT00368849 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01926639 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02691611 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT03422718 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04791852 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02510482 — Safety Biomarker (SAF): Cardiac troponin T
Genes: TNNT2
Study NCT02510482 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT04261595 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study NCT04261595 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01729650 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01667614 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01667614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02277522 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02810327 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT03611270 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT03611270 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01967875 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT01281306 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01609192 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT02296801 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02296801 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03166956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03166956 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT02079870 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00132483 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01131650 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00307242 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03565653 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02040064 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02487888 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT02487888 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02705768 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT03053310 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT01454479 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01454479 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01454479 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00348413 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02817204 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01557764 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00676793 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT04627012 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01992848 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01899677 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT01899677 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01899677 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT02422082 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02083211 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02083211 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00106561 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02763995 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02763995 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00318864 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00318864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04483947 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study NCT03408145 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00425477 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00515593 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00476996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01609387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01746875 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01746875 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00654745 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02770313 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02337946 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01390831 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02980536 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02980536 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01784536 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01784536 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01784536 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01784536 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT02150382 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03360669 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01121575 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01121575 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT01121575 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01121575 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02823041 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02823041 — Safety Biomarker (SAF): BDNF
Study NCT03529149 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02195934 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01959971 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01959971 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01959971 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00409760 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00129896 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04432584 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT04457570 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02787603 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT04578132 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02862548 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04851002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04851002 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT04851002 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT04038398 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03555344 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04405388 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04358562 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00145327 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01359384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01359384 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study NCT01359384 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT04393428 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study NCT01526369 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00066924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03561740 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04049084 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT04130854 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04130854 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01666314 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00008268 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00732693 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00732693 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00868270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT06391515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06391515 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT01050842 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT06447896 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03536962 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02082093 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01140139 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04249739 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00428077 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00428077 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03729479 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02966925 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01032278 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00647023 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02294695 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02325687 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02325687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02325687 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02325687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02325687 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03730701 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01895647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01895647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01895647 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT01895647 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT02697422 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03758950 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00645658 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00729807 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00729807 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT00360854 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03061318 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study NCT03061318 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study NCT03061318 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT03061318 — Predictive Biomarker (PRD): CLDN1 mRNA
Genes: CLDN1; CLD1; SEMP1; UNQ481/PRO944
Study NCT03061318 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT03061318 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study NCT03994393 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03019588 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01582256 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT01993758 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03317262 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03624036 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT02708706 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02774278 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02774278 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02774278 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01725256 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT01725256 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02979470 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study NCT02979470 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT02979470 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT03897192 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03169972 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT05362539 — Predictive Biomarker (PRD): GATA4 mRNA
Genes: GATA4
Study NCT05362539 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT05362539 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study NCT05362539 — Pharmacodynamic Biomarker (PDY): CD99 antigen
Genes: CD99; MIC2; MIC2X; MIC2Y
Study NCT00294567 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02717962 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00909935 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03343574 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04538898 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT00552058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00795405 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04259242 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03604627 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03149861 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02196909 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study NCT00489372 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00298857 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00003107 — Safety Biomarker (SAF): Interleukin 12
Study NCT01507727 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01590966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2