TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17344507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17344507 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1884880 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19365786 — Predictive Biomarker (PRD): C4A mRNA
Genes: C4A; CO4; CPAMD2
Study 19365786 — Monitoring Biomarker (MOI): Complement C4
Study 15526723 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11424516 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 7712308 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 21508208 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11401930 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11401930 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 11401930 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 11401930 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28760751 — Surrogate Endpoint (SUR): Serum creatinine
Study 18999981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18999981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31287198 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31287198 — Predictive Biomarker (PRD): Hormone receptor
Study 29500541 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 21090335 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 7040192 — Predictive Biomarker (PRD): LYN mRNA
Genes: LYN; JTK8
Study 7040192 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30967869 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 30967869 — Predictive Biomarker (PRD): FCN2 mRNA
Genes: FCN2; FCNL
Study 27381286 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27381286 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17577027 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 17577027 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17577027 — Predictive Biomarker (PRD): Hormone receptor
Study 31319165 — Surrogate Endpoint (SUR): Serum creatinine
Study 18050378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14672962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29141665 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 12841798 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12841798 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10822931 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 1626799 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 1626799 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1626799 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 28786423 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 17384453 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 7482412 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7482412 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25082741 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 17606725 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12189358 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 678389 — Surrogate Endpoint (SUR): Serum uric acid
Study 26375464 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20535607 — Surrogate Endpoint (SUR): Bone mineral density
Study 20535607 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15872336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10576182 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10576182 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31901799 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 24947034 — Predictive Biomarker (PRD): MMP12 mRNA
Genes: MMP12; HME
Study 17460697 — Predictive Biomarker (PRD): CDKAL1 mRNA
Genes: CDKAL1
Study 17460697 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 9536449 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31017556 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 21252252 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21252252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16413556 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 10269521 — Surrogate Endpoint (SUR): Blood pressure
Study 26758532 — Surrogate Endpoint (SUR): Blood pressure
Study 17604363 — Monitoring Biomarker (MOI): HBV DNA
Study 11692352 — Surrogate Endpoint (SUR): Blood pressure
Study 29903093 — Safety Biomarker (SAF): Reactive oxygen species
Study 15042359 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 11948037 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7616869 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30500939 — Predictive Biomarker (PRD): DSE mRNA
Genes: DSE; SART2
Study 30500939 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30500939 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30500939 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 30500939 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25424601 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 25424601 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25424601 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21140164 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21140164 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21140164 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 21140164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21140164 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21140164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29659887 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27598803 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24670328 — Surrogate Endpoint (SUR): Blood pressure
Study 8773862 — Surrogate Endpoint (SUR): Blood pressure
Study 6641534 — Surrogate Endpoint (SUR): Serum creatinine
Study 30151903 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 9753292 — Surrogate Endpoint (SUR): Blood pressure
Study 7822563 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31307674 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 1794360 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31777547 — Predictive Biomarker (PRD): miR-106b
Genes: MIR106B
Study 27473749 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 27473749 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 22978414 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 2575367 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19911481 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26786148 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20610444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18825581 — Surrogate Endpoint (SUR): Blood pressure
Study 26156412 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26156412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26156412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21779958 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 12475391 — Surrogate Endpoint (SUR): Serum testosterone
Study 8160616 — Surrogate Endpoint (SUR): Blood pressure
Study 14624699 — Surrogate Endpoint (SUR): Blood pressure
Study 8925993 — Surrogate Endpoint (SUR): Blood pressure
Study 27955682 — Surrogate Endpoint (SUR): Blood pressure
Study 8524604 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 21784309 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 21784309 — Surrogate Endpoint (SUR): Bone mineral density
Study 18795291 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18795291 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18795291 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15553594 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22863265 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 16304303 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9717598 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28794253 — Surrogate Endpoint (SUR): Blood pressure
Study 12630068 — Surrogate Endpoint (SUR): Blood pressure
Study 9527278 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9527278 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9527278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 390339 — Surrogate Endpoint (SUR): Blood pressure
Study 30836637 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26511146 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11699043 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 9042633 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9042633 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 3285838 — Surrogate Endpoint (SUR): Blood pressure
Study 24725169 — Surrogate Endpoint (SUR): Blood pressure
Study 17127698 — Surrogate Endpoint (SUR): Serum creatinine
Study 15894902 — Surrogate Endpoint (SUR): Blood pressure
Study 16531889 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1725022 — Surrogate Endpoint (SUR): Blood pressure
Study 26663712 — Surrogate Endpoint (SUR): Blood pressure
Study 1714670 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31336633 — Surrogate Endpoint (SUR): Blood pressure
Study 30380279 — Surrogate Endpoint (SUR): Blood pressure
Study 20214224 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3332574 — Surrogate Endpoint (SUR): Blood pressure
Study 26449739 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19338146 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 21077943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21077943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21077943 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21077943 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11392465 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9589227 — Surrogate Endpoint (SUR): Blood pressure
Study 2548553 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 780059 — Surrogate Endpoint (SUR): Blood pressure
Study 24156702 — Surrogate Endpoint (SUR): Serum creatinine
Study 24156702 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24156702 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24156702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12556655 — Surrogate Endpoint (SUR): Blood pressure
Study 10953181 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25236873 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25236873 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18677174 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18677174 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18677174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16816482 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 16816482 — Surrogate Endpoint (SUR): Bone mineral density
Study 9952390 — Predictive Biomarker (PRD): RNASE2 mRNA
Genes: RNASE2; EDN; RNS2
Study 8603281 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 16791013 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10780755 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 7871065 — Surrogate Endpoint (SUR): Blood pressure
Study 18794896 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18794896 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 12139807 — Safety Biomarker (SAF): Hyaluronic acid
Study 2031393 — Surrogate Endpoint (SUR): Blood pressure
Study 7111875 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20200198 — Surrogate Endpoint (SUR): Serum uric acid
Study 16078088 — Surrogate Endpoint (SUR): Blood pressure
Study 12384826 — Surrogate Endpoint (SUR): Blood pressure
Study 9766253 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24452393 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 24452393 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8517952 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31783028 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 19833271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25500887 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17190104 — Surrogate Endpoint (SUR): Serum calcium
Study 9253878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9253878 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9253878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9253878 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9253878 — Safety Biomarker (SAF): Interleukin 1
Study 9253878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28546852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28546852 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 23532686 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 30685386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29765212 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 29765212 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24374936 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 6127890 — Surrogate Endpoint (SUR): Blood pressure
Study 31563406 — Surrogate Endpoint (SUR): Blood pressure
Study 27254743 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 24478050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24478050 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17209660 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 17209660 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 17209660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2073165 — Surrogate Endpoint (SUR): Blood pressure
Study 30488229 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 17347471 — Surrogate Endpoint (SUR): Blood pressure
Study 14990013 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23910581 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21142788 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 21142788 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 21142788 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21142788 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 19695193 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 9141918 — Surrogate Endpoint (SUR): Blood pressure
Study 9141918 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7894222 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7894222 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22981306 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 18720323 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 20400005 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20400005 — Surrogate Endpoint (SUR): Blood pressure
Study 28923692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27942103 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 25640401 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 12904894 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 31924544 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31924544 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25138758 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 23334732 — Surrogate Endpoint (SUR): Bone mineral density
Study 8866496 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 31532902 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 31532902 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23015655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9468459 — Surrogate Endpoint (SUR): Blood pressure
Study 8181121 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27163358 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 19726302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19726302 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7951402 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7951402 — Surrogate Endpoint (SUR): Bone mineral density
Study 19751459 — Surrogate Endpoint (SUR): Blood pressure
Study 17456720 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 17456720 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 26370515 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23948351 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18950332 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18950332 — Surrogate Endpoint (SUR): Blood pressure
Study 17163246 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1071672 — Surrogate Endpoint (SUR): Blood pressure
Study 24140326 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20875186 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19017760 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17712643 — Surrogate Endpoint (SUR): Serum creatinine
Study 17712643 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15104196 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9848301 — Surrogate Endpoint (SUR): Serum testosterone
Study 2344168 — Surrogate Endpoint (SUR): Bacterial count
Study 7002691 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17197435 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 17197435 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 17197435 — Predictive Biomarker (PRD): XRCC3 mRNA
Genes: XRCC3
Study 11395033 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 3574137 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 15295720 — Surrogate Endpoint (SUR): Blood pressure
Study 31621189 — Safety Biomarker (SAF): Hyaluronic acid
Study 19960974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19960974 — Surrogate Endpoint (SUR): Serum creatinine
Study 8975854 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25743819 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 25743819 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30415432 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29686818 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 24647464 — Predictive Biomarker (PRD): Hormone receptor
Study 20032478 — Surrogate Endpoint (SUR): Blood pressure
Study 20032478 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE