TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00122005 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02614872 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT04287998 — Predictive Biomarker (PRD): MXRA5 mRNA
Genes: MXRA5
Study NCT04287998 — Predictive Biomarker (PRD): ANXA4 mRNA
Genes: ANXA4; ANX4
Study NCT04287998 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02099630 — Safety Biomarker (SAF): BDNF
Study NCT00931450 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT03375684 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01002534 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study NCT03264508 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03077373 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05203601 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT04355156 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03961763 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03961763 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01346163 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT03706989 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01594177 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01594177 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01416766 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02840058 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02840058 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02840058 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02988843 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT01047475 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT02662803 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02662803 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT02061722 — Predictive Biomarker (PRD): PDE10A mRNA
Genes: PDE10A
Study NCT05683769 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT05683769 — Safety Biomarker (SAF): miR-140
Genes: MIR140
Study NCT05683769 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study NCT05683769 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT05683769 — Safety Biomarker (SAF): miR-181a
Study NCT05683769 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study NCT05683769 — Monitoring Biomarker (MOI): miR-26a
Study NCT04044768 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00385450 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04741100 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study NCT04741100 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04062409 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03097393 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01509248 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01114256 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT01224808 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT01302496 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study NCT01302496 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01302496 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study NCT01302496 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00353353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00466258 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01741064 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT06534424 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT06534424 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02421367 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04256980 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT03376503 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03376503 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT00832338 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03154203 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04392271 — Safety Biomarker (SAF): Beta-N-acetylhexosaminidase
Genes: OGA; HEXC; KIAA0679; MEA5; MGEA5
Study NCT01991249 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT01991249 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study NCT01991249 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study NCT01991249 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01991249 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01991249 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study NCT01991249 — Predictive Biomarker (PRD): PAX5 mRNA
Genes: PAX5
Study NCT00152490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03324542 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03324542 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01089283 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT01089283 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT00974636 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04405323 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03924388 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01505205 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01505205 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT01505205 — Predictive Biomarker (PRD): ANO1 mRNA
Genes: ANO1; DOG1; ORAOV2; TAOS2; TMEM16A
Study NCT02087605 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01399515 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02305901 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT01151826 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT00277381 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02679001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03252028 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT02597998 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT02676986 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00108927 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04100200 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT05703308 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study NCT01466296 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT03594032 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT01714102 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00089713 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04664595 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03477786 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02198586 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01524653 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT06059326 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03209401 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00249873 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00028002 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT00028002 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study NCT01136252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02731313 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03664037 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study NCT01121939 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01121939 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01121939 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04375670 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT02590068 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01636570 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01340430 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01340430 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02668120 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study NCT04599699 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03789097 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04317469 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04317469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02068183 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03615755 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02079766 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03165721 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study NCT01658228 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02348983 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02923388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04510285 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04510285 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03365882 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02088684 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02088684 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02088684 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02088684 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02088684 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00521651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00521651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00521651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02315287 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00883480 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00883480 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00326768 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02088827 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02088827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03649321 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT00981357 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study NCT03968549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01026701 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT04523844 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03157856 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03639311 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03101878 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study NCT02853279 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01901666 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT01901666 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01901666 — Predictive Biomarker (PRD): JUN mRNA
Genes: JUN
Study NCT01901666 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT01901666 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01971489 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study NCT01971489 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04133376 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02185690 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02347501 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00005576 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00005576 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05867056 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00538941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04543370 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04024787 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03786094 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03844321 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01939730 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03101397 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT01503983 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01933347 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02216747 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04181398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04181398 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01565005 — Predictive Biomarker (PRD): ASPM mRNA
Genes: ASPM; MCPH5
Study NCT01565005 — Predictive Biomarker (PRD): MCPH1 mRNA
Genes: MCPH1
Study NCT01565005 — Predictive Biomarker (PRD): WDR62 mRNA
Genes: WDR62; C19orf14
Study NCT01565005 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study NCT01565005 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study NCT01565005 — Predictive Biomarker (PRD): PCNT mRNA
Genes: PCNT; KIAA0402; PCNT2
Study NCT01883323 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04480892 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04480892 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT05217823 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT06354504 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT00859131 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02828709 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03186326 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03186326 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03186326 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT02050022 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT05419167 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02868580 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04088760 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00963976 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00550173 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00550173 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06736353 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03820531 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study NCT03820531 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03820531 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study NCT05107245 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03395210 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01854294 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01854294 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01854294 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT01997203 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01130623 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02068248 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT02444585 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02916992 — Predictive Biomarker (PRD): FLCN mRNA
Genes: FLCN; BHD
Study NCT02188641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02188641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02188641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02188641 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT02837757 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05586737 — Predictive Biomarker (PRD): NLRP5 mRNA
Genes: NLRP5; MATER; NALP5
Study NCT03615300 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03486990 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT03486990 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00867490 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03246425 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01389063 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT01625195 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02726399 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03203447 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03311152 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00404859 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02408731 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02608385 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04414657 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02276443 — Predictive Biomarker (PRD): DCLRE1C mRNA
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study NCT03075462 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00002789 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00765648 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01418040 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00740493 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04263337 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study NCT04263337 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT03148847 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02899871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00190359 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT02587689 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT04331834 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00197431 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study NCT01276665 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04113330 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study NCT04598347 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01406210 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study NCT00880672 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00880672 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03417882 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study NCT03417882 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03417882 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03417882 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00005325 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02092038 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00186342 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study NCT04378686 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03299062 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT04413344 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study NCT04398940 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01290419 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03049488 — Surrogate Endpoint (SUR): Neutralizing antibody