TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10196011 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21854162 — Surrogate Endpoint (SUR): Blood pressure
Study 19957871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9327037 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9040027 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 16784930 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16784930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16784930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22057829 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17432690 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 29869903 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 29869903 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 29869903 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19092349 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 19092349 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19092349 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 19092349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19092349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19092349 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21237718 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9543281 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26650626 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 26650626 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 17701405 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8653534 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26496331 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24852180 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 24852180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24852180 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 24852180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24852180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24852180 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20600033 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 17850684 — Surrogate Endpoint (SUR): Blood pressure
Study 15220247 — Surrogate Endpoint (SUR): Blood pressure
Study 9209004 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3578544 — Surrogate Endpoint (SUR): Blood pressure
Study 19540739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27334521 — Surrogate Endpoint (SUR): Blood pressure
Study 21277062 — Surrogate Endpoint (SUR): Blood pressure
Study 16488953 — Safety Biomarker (SAF): Hyaluronic acid
Study 15602823 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15602823 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27770188 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27770188 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 24490949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17689142 — Surrogate Endpoint (SUR): Blood pressure
Study 26927249 — Surrogate Endpoint (SUR): Bone mineral density
Study 22332914 — Surrogate Endpoint (SUR): Blood pressure
Study 10978986 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1610863 — Surrogate Endpoint (SUR): Serum creatinine
Study 24626733 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24626733 — Surrogate Endpoint (SUR): Blood pressure
Study 21053992 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23614849 — Surrogate Endpoint (SUR): Blood pressure
Study 16549465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31146305 — Surrogate Endpoint (SUR): Blood pressure
Study 19894656 — Surrogate Endpoint (SUR): Blood pressure
Study 11405344 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 28838583 — Safety Biomarker (SAF): DRD2
Study 23335369 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 23335369 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 23335369 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 6144266 — Surrogate Endpoint (SUR): Blood pressure
Study 29867230 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23440143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23440143 — Surrogate Endpoint (SUR): Blood pressure
Study 26152757 — Surrogate Endpoint (SUR): Blood pressure
Study 22465650 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 20565999 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 17629719 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 30393104 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10501246 — Predictive Biomarker (PRD): HEXIM2 mRNA
Genes: HEXIM2; L3
Study 8689808 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30366115 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 21805588 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 30730896 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 25139195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21628399 — Predictive Biomarker (PRD): Liver iron
Study 9314346 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 3521767 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30307466 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 30307466 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30307466 — Surrogate Endpoint (SUR): Pathological complete response
Study 22544891 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 6151343 — Surrogate Endpoint (SUR): Blood pressure
Study 28744111 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 21730017 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18946429 — Surrogate Endpoint (SUR): Blood pressure
Study 30791735 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 2541159 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2541159 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 31561272 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 25759378 — Predictive Biomarker (PRD): CLDN7 mRNA
Genes: CLDN7; CEPTRL2; CPETRL2
Study 21947374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11585004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25742888 — Surrogate Endpoint (SUR): Serum uric acid
Study 23004926 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1571205 — Surrogate Endpoint (SUR): Serum creatinine
Study 15829577 — Surrogate Endpoint (SUR): Bone mineral density
Study 25736283 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25736283 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25736283 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23444983 — Surrogate Endpoint (SUR): Serum testosterone
Study 10975476 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 12716487 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12716487 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11134132 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15157751 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15157751 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15157751 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9305603 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2423807 — Surrogate Endpoint (SUR): Blood pressure
Study 31975638 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26072289 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 26072289 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18789492 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 18789492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18789492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18789492 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16305570 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9708557 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study 2225366 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 2225366 — Surrogate Endpoint (SUR): Blood pressure
Study 23985260 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30170956 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31590924 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 25661195 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 23417515 — Safety Biomarker (SAF): DRD2
Study 11232592 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 11232592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18000094 — Surrogate Endpoint (SUR): Bone mineral density
Study 12796135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12796135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31620886 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31620886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24857206 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20357732 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20357732 — Surrogate Endpoint (SUR): Blood pressure
Study 15616085 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15616085 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15616085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2231883 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study 26303520 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 12919178 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12919178 — Surrogate Endpoint (SUR): Serum testosterone
Study 813053 — Surrogate Endpoint (SUR): Blood pressure
Study 23355629 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23355629 — Surrogate Endpoint (SUR): Blood pressure
Study 17710816 — Predictive Biomarker (PRD): FAS mRNA
Genes: FAS; APT1; FAS1; TNFRSF6
Study 6321674 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22845337 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 16940886 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15236618 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9379661 — Surrogate Endpoint (SUR): Blood pressure
Study 21654755 — Surrogate Endpoint (SUR): Blood pressure
Study 21654755 — Surrogate Endpoint (SUR): Serum creatinine
Study 16949481 — Surrogate Endpoint (SUR): Serum creatinine
Study 9180240 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9180240 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26154338 — Surrogate Endpoint (SUR): Blood pressure
Study 16541243 — Surrogate Endpoint (SUR): Blood pressure
Study 12704403 — Surrogate Endpoint (SUR): Blood pressure
Study 9283061 — Surrogate Endpoint (SUR): Blood pressure
Study 29373432 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 26522923 — Surrogate Endpoint (SUR): Bone mineral density
Study 24439972 — Surrogate Endpoint (SUR): Blood pressure
Study 20212299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8942420 — Surrogate Endpoint (SUR): Blood pressure
Study 27084855 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 27084855 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24799054 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22814329 — Surrogate Endpoint (SUR): Serum creatinine
Study 2524360 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2524360 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27582078 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27582078 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 16882163 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 16882163 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 16882163 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 16882163 — Predictive Biomarker (PRD): CYP2C18 mRNA
Genes: CYP2C18
Study 16882163 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 16882163 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 16882163 — Predictive Biomarker (PRD): CYP26A1 mRNA
Genes: CYP26A1; CYP26; P450RAI1
Study 16882163 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 12928710 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 11211541 — Surrogate Endpoint (SUR): Blood pressure
Study 6829481 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6829481 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15887009 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9799756 — Surrogate Endpoint (SUR): Bone mineral density
Study 28588021 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25881936 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2198211 — Predictive Biomarker (PRD): SULT1A3 mRNA
Genes: SULT1A3; STM
Study 333869 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28012035 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 19786646 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 19786646 — Surrogate Endpoint (SUR): Blood pressure
Study 9099655 — Surrogate Endpoint (SUR): Blood pressure
Study 30111294 — Surrogate Endpoint (SUR): Blood pressure
Study 26692193 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 22421745 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 15070939 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 15070939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29431520 — Surrogate Endpoint (SUR): Blood pressure
Study 29431520 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29431520 — Safety Biomarker (SAF): Reactive oxygen species
Study 27611858 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27611858 — Predictive Biomarker (PRD): AZGP1 mRNA
Genes: AZGP1; ZAG; ZNGP1
Study 27611858 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25281710 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 8903111 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 8903111 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 31794512 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19531929 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19531929 — Surrogate Endpoint (SUR): Bone mineral density
Study 15465622 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 11204435 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 11204435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7905730 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1463155 — Surrogate Endpoint (SUR): Blood pressure
Study 23945905 — Surrogate Endpoint (SUR): Blood pressure
Study 10891823 — Surrogate Endpoint (SUR): Blood pressure
Study 8937963 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 8937963 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2868748 — Surrogate Endpoint (SUR): Blood pressure
Study 30388041 — Surrogate Endpoint (SUR): Blood pressure
Study 20074276 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17609872 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 12229137 — Surrogate Endpoint (SUR): Blood pressure
Study 7752567 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15166130 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 7974375 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7974375 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 4580022 — Surrogate Endpoint (SUR): Blood pressure
Study 15540297 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19271169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19271169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16620350 — Surrogate Endpoint (SUR): Blood pressure
Study 15006431 — Surrogate Endpoint (SUR): Blood pressure
Study 9184265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9184265 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9184265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9184265 — Safety Biomarker (SAF): IL-6 and IL-10
Study 30326764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28455782 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 23379741 — Surrogate Endpoint (SUR): Blood pressure
Study 15543449 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 3052167 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31785175 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15288411 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 28689453 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26537218 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 14977817 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 20545993 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20545993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12067917 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 31464525 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24666696 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 23082701 — Monitoring Biomarker (MOI): HBV DNA
Study 14680343 — Surrogate Endpoint (SUR): Blood pressure
Study 14680343 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14680343 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24631057 — Surrogate Endpoint (SUR): Blood pressure
Study 22588047 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22588047 — Surrogate Endpoint (SUR): Blood pressure
Study 18391640 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1659253 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31364872 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 3108355 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 3108355 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 1833897 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26674998 — Surrogate Endpoint (SUR): Blood pressure
Study 19852292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19852292 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 791319 — Surrogate Endpoint (SUR): Blood pressure
Study 29348183 — Predictive Biomarker (PRD): Neuromedin-U
Genes: NMU
Study 27912875 — Surrogate Endpoint (SUR): Blood pressure
Study 24462735 — Monitoring Biomarker (MOI): HBV DNA
Study 21122701 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18294814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16796928 — Surrogate Endpoint (SUR): Pulmonary vascular resistance