TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31624333 — Predictive Biomarker (PRD): UNC13A mRNA
Genes: UNC13A; KIAA1032
Study 31624333 — Predictive Biomarker (PRD): MOBP mRNA
Genes: MOBP
Study 27906937 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 24988203 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20523253 — Surrogate Endpoint (SUR): Blood pressure
Study 16165272 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 16165272 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10858488 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6469434 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6469434 — Surrogate Endpoint (SUR): Blood pressure
Study 9465753 — Surrogate Endpoint (SUR): Blood pressure
Study 19340730 — Surrogate Endpoint (SUR): Blood pressure
Study 8675249 — Surrogate Endpoint (SUR): Blood pressure
Study 29649377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22408124 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 22408124 — Surrogate Endpoint (SUR): Bone mineral density
Study 30612116 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 22381043 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22381043 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17636152 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17636152 — Surrogate Endpoint (SUR): Blood pressure
Study 9920517 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9920517 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2078483 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28402353 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25906791 — Surrogate Endpoint (SUR): Bone mineral density
Study 15579192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9757170 — Surrogate Endpoint (SUR): Blood pressure
Study 21620782 — Predictive Biomarker (PRD): ARHGEF5 mRNA
Genes: ARHGEF5; TIM
Study 26799126 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25618966 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20453655 — Surrogate Endpoint (SUR): Blood pressure
Study 15124680 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 9886723 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9886723 — Surrogate Endpoint (SUR): Blood pressure
Study 8290176 — Surrogate Endpoint (SUR): Blood pressure
Study 8290176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18241283 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 2906344 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2906344 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30840530 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26021996 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19217817 — Surrogate Endpoint (SUR): Bone mineral density
Study 17196811 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9152189 — Surrogate Endpoint (SUR): Serum calcium
Study 8239794 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16159645 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11966737 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23712970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11575340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12766604 — Safety Biomarker (SAF): 51Cr-EDTA
Study 8983335 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8983335 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 22305828 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20226286 — Surrogate Endpoint (SUR): Bone mineral density
Study 6347752 — Surrogate Endpoint (SUR): Blood pressure
Study 24347519 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24347519 — Predictive Biomarker (PRD): Hormone receptor
Study 11586699 — Surrogate Endpoint (SUR): Blood pressure
Study 17976724 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17976724 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 6586395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 24952700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24952700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24952700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24952700 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 24952700 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15641091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28914592 — Safety Biomarker (SAF): Hyaluronic acid
Study 27085637 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 15580062 — Surrogate Endpoint (SUR): Blood pressure
Study 8003095 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20976769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30991720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30991720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30991720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30991720 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 26336926 — Safety Biomarker (SAF): Reactive oxygen species
Study 2190013 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 29180855 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 21466532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21466532 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17298695 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 14662708 — Surrogate Endpoint (SUR): Blood pressure
Study 11703963 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11703963 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11703963 — Surrogate Endpoint (SUR): Blood pressure
Study 9390726 — Safety Biomarker (SAF): DRD2
Study 3309653 — Surrogate Endpoint (SUR): Blood pressure
Study 11818769 — Surrogate Endpoint (SUR): Blood pressure
Study 7492104 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1826989 — Surrogate Endpoint (SUR): Blood pressure
Study 30292773 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 25085517 — Predictive Biomarker (PRD): DBNL mRNA
Genes: DBNL; CMAP; SH3P7; PP5423
Study 27055965 — Surrogate Endpoint (SUR): Blood pressure
Study 27055965 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27055965 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20954287 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 20954287 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 16107961 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 7539852 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7539852 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7539852 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10928302 — Surrogate Endpoint (SUR): Blood pressure
Study 4001836 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21144938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21144938 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12198044 — Surrogate Endpoint (SUR): Blood pressure
Study 11575576 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18465343 — Surrogate Endpoint (SUR): Bone mineral density
Study 1391258 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16762982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 13678868 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30638985 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28853992 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19122552 — Surrogate Endpoint (SUR): Blood pressure
Study 12872150 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11091498 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11091498 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3454368 — Surrogate Endpoint (SUR): Blood pressure
Study 27941973 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 27941973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24888857 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 20307657 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 18593715 — Predictive Biomarker (PRD): CHRNB2 mRNA
Genes: CHRNB2
Study 8891515 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 1747959 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25847941 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 22822075 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 22822075 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22822075 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 16310576 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16310576 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2718706 — Surrogate Endpoint (SUR): Blood pressure
Study 2718706 — Surrogate Endpoint (SUR): Serum creatinine
Study 31285228 — Surrogate Endpoint (SUR): Serum creatinine
Study 17721103 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14562945 — Monitoring Biomarker (MOI): HBV DNA
Study 10477361 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 1655223 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 29528499 — Surrogate Endpoint (SUR): Serum sodium
Study 27464860 — Surrogate Endpoint (SUR): Blood pressure
Study 23431348 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18633426 — Surrogate Endpoint (SUR): Blood pressure
Study 8606901 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2015727 — Surrogate Endpoint (SUR): Blood pressure
Study 31553833 — Safety Biomarker (SAF): Interleukin 12
Study 15191261 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 31307913 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31307913 — Surrogate Endpoint (SUR): Serum hemoglobin A1C
Study 31307913 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28645227 — Surrogate Endpoint (SUR): Blood pressure
Study 28645227 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25643928 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 10573618 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8706070 — Surrogate Endpoint (SUR): Blood pressure
Study 8706070 — Surrogate Endpoint (SUR): Serum uric acid
Study 6918402 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18552616 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 23044236 — Monitoring Biomarker (MOI): HBV DNA
Study 11916440 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 11916440 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11861034 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 10455479 — Surrogate Endpoint (SUR): Blood pressure
Study 18218295 — Surrogate Endpoint (SUR): Blood pressure
Study 17050889 — Surrogate Endpoint (SUR): Bone mineral density
Study 10933118 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 3246212 — Predictive Biomarker (PRD): BLOC1S4 mRNA
Genes: BLOC1S4; CNO
Study 30900815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30900815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18046666 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14730412 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 1338525 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24344160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11472461 — Surrogate Endpoint (SUR): Blood pressure
Study 11472461 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2930837 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2930837 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28448688 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23868627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8236505 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22464647 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 22464647 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 16360994 — Surrogate Endpoint (SUR): Serum creatinine
Study 28550080 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 26494444 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 26494444 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21148765 — Surrogate Endpoint (SUR): Blood pressure
Study 16669849 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12792293 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12792293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11111206 — Surrogate Endpoint (SUR): Blood pressure
Study 8975873 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20146168 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18780883 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 9122732 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3781681 — Surrogate Endpoint (SUR): Blood pressure
Study 27502865 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25335328 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25335328 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25335328 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22215753 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11776606 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 8874334 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17532829 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10440916 — Surrogate Endpoint (SUR): Blood pressure
Study 30991718 — Surrogate Endpoint (SUR): Blood pressure
Study 30991718 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25592197 — Surrogate Endpoint (SUR): Blood pressure
Study 21368320 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 21368320 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17498486 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17498486 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27736846 — Predictive Biomarker (PRD): FGD4 mRNA
Genes: FGD4; FRABP; ZFYVE6
Study 27736846 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27736846 — Predictive Biomarker (PRD): TUBB2A mRNA
Genes: TUBB2A; TUBB2
Study 27736846 — Predictive Biomarker (PRD): EPHA5 mRNA
Genes: EPHA5; BSK; EHK1; HEK7; TYRO4
Study 17635371 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28445888 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22204993 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22204993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22204993 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29020689 — Predictive Biomarker (PRD): TPPP mRNA
Genes: TPPP; TPPP1
Study 24038561 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30390699 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 24897342 — Safety Biomarker (SAF): RYR1
Genes: RYR; PPP1R137
Study 24897342 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24897342 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24897342 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8642232 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8642232 — Surrogate Endpoint (SUR): Blood pressure
Study 7840022 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18430270 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18430270 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18430270 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2772857 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31165721 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 12385860 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15743000 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 9040746 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 9040746 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 7684155 — Surrogate Endpoint (SUR): Serum sodium
Study 30672232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30672232 — Safety Biomarker (SAF): Interleukin 1
Study 30672232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17627404 — Surrogate Endpoint (SUR): Bone mineral density
Study 11152019 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1505560 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2426934 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 12374900 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12374900 — Surrogate Endpoint (SUR): Blood pressure
Study 2680273 — Surrogate Endpoint (SUR): Blood pressure
Study 31132893 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 29331037 — Surrogate Endpoint (SUR): Blood pressure
Study 26786929 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 22873651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22873651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22873651 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12037148 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12404164 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16860807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16860807 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16860807 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16860807 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 14969666 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 24166522 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17708161 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11521723 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 3285731 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25111236 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 25111236 — Surrogate Endpoint (SUR): Blood pressure
Study 21954530 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 11153551 — Surrogate Endpoint (SUR): Blood pressure
Study 9342546 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 3939740 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 26042474 — Predictive Biomarker (PRD): OPRD1 mRNA
Genes: OPRD1; OPRD
Study 26042474 — Predictive Biomarker (PRD): OPRK1 mRNA
Genes: OPRK1; OPRK
Study 9282973 — Safety Biomarker (SAF): 51Cr-EDTA
Study 27006510 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24736279 — Surrogate Endpoint (SUR): Blood pressure
Study 17681081 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 15117739 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9263140 — Surrogate Endpoint (SUR): Bone mineral density
Study 3545273 — Surrogate Endpoint (SUR): Blood pressure
Study 27657514 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 24183837 — Surrogate Endpoint (SUR): Total kidney volume
Study 24183837 — Surrogate Endpoint (SUR): Serum creatinine
Study 20525992 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 17928878 — Surrogate Endpoint (SUR): Blood pressure
Study 6148522 — Surrogate Endpoint (SUR): Blood pressure
Study 21902692 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 21902692 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 21902692 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 8854471 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 1291184 — Predictive Biomarker (PRD): SI mRNA
Genes: SI