TrialPanorama/TrialPanorama-database huggingface dataset:
Study 3057329 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26346429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19368965 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11325461 — Surrogate Endpoint (SUR): Blood pressure
Study 7934158 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29194612 — Safety Biomarker (SAF): miR-16
Study 29194612 — Predictive Biomarker (PRD): miR-17
Genes: MIR17
Study 29194612 — Safety Biomarker (SAF): miR-128
Study 29194612 — Pharmacodynamic Biomarker (PDY): miR-132
Genes: MIR132
Study 29194612 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 29194612 — Safety Biomarker (SAF): miR-15a
Genes: MIR15A
Study 29194612 — Predictive Biomarker (PRD): miR-106b
Genes: MIR106B
Study 29194612 — Predictive Biomarker (PRD): miR-31
Genes: MIR31
Study 29194612 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-150
Genes: MIR150
Study 28753849 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 28753849 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18485309 — Surrogate Endpoint (SUR): Blood pressure
Study 17175661 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 10883417 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 10883417 — Surrogate Endpoint (SUR): Blood pressure
Study 30260551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30260551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27415448 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11577787 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 9164894 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9196864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9196864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9196864 — Safety Biomarker (SAF): Interleukin 1
Study 9196864 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1458789 — Safety Biomarker (SAF): Interleukin 1
Study 1458789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9334157 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 8420041 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 8420041 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 30379749 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 28121470 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23832863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18666468 — Surrogate Endpoint (SUR): Bone mineral density
Study 27283365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26088042 — Surrogate Endpoint (SUR): Serum sodium
Study 11489026 — Surrogate Endpoint (SUR): Blood pressure
Study 8089244 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22683294 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 22683294 — Predictive Biomarker (PRD): DSE mRNA
Genes: DSE; SART2
Study 19097507 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 15998785 — Surrogate Endpoint (SUR): Bone mineral density
Study 12122230 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31446153 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31446153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31446153 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 29064743 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17136563 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17136563 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 17136563 — Predictive Biomarker (PRD): KLRD1 mRNA
Genes: KLRD1; CD94
Study 6384455 — Surrogate Endpoint (SUR): Serum sodium
Study 21275630 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 16730271 — Predictive Biomarker (PRD): Hormone receptor
Study 29791971 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21684012 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 21684012 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 14581723 — Surrogate Endpoint (SUR): Serum creatinine
Study 29475874 — Surrogate Endpoint (SUR): Blood pressure
Study 282073 — Surrogate Endpoint (SUR): Blood pressure
Study 25569647 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 25569647 — Surrogate Endpoint (SUR): Blood pressure
Study 23052625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23052625 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9140680 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1646068 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21130598 — Surrogate Endpoint (SUR): Bone mineral density
Study 25960403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25960403 — Surrogate Endpoint (SUR): Blood pressure
Study 25960403 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24091175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24091175 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21779829 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 19786444 — Surrogate Endpoint (SUR): Blood pressure
Study 15349783 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15349783 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 11117271 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7505143 — Monitoring Biomarker (MOI): HBV DNA
Study 31491931 — Surrogate Endpoint (SUR): Blood pressure
Study 10874261 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10874261 — Surrogate Endpoint (SUR): Blood pressure
Study 8517425 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8582495 — Surrogate Endpoint (SUR): Blood pressure
Study 26394017 — Surrogate Endpoint (SUR): Blood pressure
Study 17268121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30914312 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 10874989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31054246 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 31054246 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 31054246 — Predictive Biomarker (PRD): GPR55 mRNA
Genes: GPR55
Study 31054246 — Predictive Biomarker (PRD): GPR119 mRNA
Genes: GPR119
Study 29026123 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 12487321 — Surrogate Endpoint (SUR): Blood pressure
Study 29050753 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 26086183 — Predictive Biomarker (PRD): NUBP1 mRNA
Genes: NUBP1; NBP; NBP1
Study 12818310 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17346248 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2136969 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 14966737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9455079 — Surrogate Endpoint (SUR): Blood pressure
Study 3285834 — Surrogate Endpoint (SUR): Serum creatinine
Study 25560051 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25560051 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 25560051 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 23067229 — Surrogate Endpoint (SUR): Blood pressure
Study 20671032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18520293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9748012 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 31714895 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 31714895 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26757835 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26757835 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20185006 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20185006 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20185006 — Surrogate Endpoint (SUR): Blood pressure
Study 20185006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8198976 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 19196360 — Surrogate Endpoint (SUR): Blood pressure
Study 15233977 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20345865 — Surrogate Endpoint (SUR): Bone mineral density
Study 31042791 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17211855 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 17211855 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 15356026 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7989710 — Monitoring Biomarker (MOI): HBV DNA
Study 1600494 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 24244635 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24244635 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 24244635 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 18347654 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18347654 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21999723 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 10737284 — Surrogate Endpoint (SUR): Blood pressure
Study 3260082 — Surrogate Endpoint (SUR): Blood pressure
Study 30169740 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 22707261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19033449 — Surrogate Endpoint (SUR): Blood pressure
Study 1130437 — Surrogate Endpoint (SUR): Blood pressure
Study 30240936 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 25547033 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 20405236 — Surrogate Endpoint (SUR): Blood pressure
Study 20146881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20146881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20146881 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20146881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2752395 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 2752395 — Surrogate Endpoint (SUR): Serum creatinine
Study 31646668 — Surrogate Endpoint (SUR): Bone mineral density
Study 20584756 — Surrogate Endpoint (SUR): Blood pressure
Study 20584756 — Surrogate Endpoint (SUR): Serum sodium
Study 9182472 — Surrogate Endpoint (SUR): Blood pressure
Study 9182472 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30657017 — Monitoring Biomarker (MOI): Procalcitonin
Study 30657017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30657017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28806917 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 19422140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16417639 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15246645 — Surrogate Endpoint (SUR): Blood pressure
Study 9573428 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31654276 — Surrogate Endpoint (SUR): Blood pressure
Study 28077584 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 19398602 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 19398602 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study 10563141 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 29653686 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 16261774 — Surrogate Endpoint (SUR): Blood pressure
Study 18076218 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11136298 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 10599601 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 7592202 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 1850576 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8724116 — Surrogate Endpoint (SUR): Blood pressure
Study 21705084 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 28801309 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28801309 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24398758 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 6230892 — Surrogate Endpoint (SUR): Blood pressure
Study 24776325 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24776325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10219067 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10219067 — Surrogate Endpoint (SUR): Blood pressure
Study 25863797 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19615989 — Monitoring Biomarker (MOI): Procalcitonin
Study 16705849 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16540949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16540949 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16540949 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21827441 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21827441 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 21827441 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17873492 — Surrogate Endpoint (SUR): Blood pressure
Study 8955576 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 24924267 — Safety Biomarker (SAF): Hyaluronic acid
Study 9040574 — Surrogate Endpoint (SUR): Blood pressure
Study 10573546 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8733734 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31676222 — Surrogate Endpoint (SUR): Bone mineral density
Study 28687275 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 22416600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22416600 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9550532 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9550532 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 9550532 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9550532 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26630216 — Surrogate Endpoint (SUR): Blood pressure
Study 26630216 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10746484 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10746484 — Surrogate Endpoint (SUR): Blood pressure
Study 20214205 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17249526 — Surrogate Endpoint (SUR): Blood pressure
Study 17249526 — Surrogate Endpoint (SUR): Serum creatinine
Study 31520576 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31520576 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 31520576 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 31520576 — Predictive Biomarker (PRD): HTR2C mRNA
Genes: HTR2C; HTR1C
Study 25134002 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19139296 — Predictive Biomarker (PRD): SCN1A mRNA
Genes: SCN1A; NAC1; SCN1
Study 17672892 — Surrogate Endpoint (SUR): Blood pressure
Study 27043952 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 23869890 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23869890 — Surrogate Endpoint (SUR): Blood pressure
Study 16815783 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7792744 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2143638 — Surrogate Endpoint (SUR): Blood pressure
Study 7438385 — Surrogate Endpoint (SUR): Blood pressure
Study 29891906 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15838676 — Surrogate Endpoint (SUR): Blood pressure
Study 10756890 — Surrogate Endpoint (SUR): Blood pressure
Study 30150128 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30150128 — Surrogate Endpoint (SUR): Blood pressure
Study 27161894 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 27161894 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 27161894 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 27161894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27161894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27161894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16042675 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16042675 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2124648 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30039199 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 30039199 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 28616765 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23537332 — Surrogate Endpoint (SUR): Blood pressure
Study 25744115 — Surrogate Endpoint (SUR): Blood pressure
Study 16856145 — Surrogate Endpoint (SUR): Blood pressure
Study 21884013 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20580035 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 20580035 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 20580035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20580035 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 16121967 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 11835038 — Surrogate Endpoint (SUR): Blood pressure
Study 10999124 — Surrogate Endpoint (SUR): Serum creatinine
Study 3886566 — Surrogate Endpoint (SUR): Blood pressure
Study 27258230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27258230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27258230 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22240359 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 20650346 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20650346 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23159100 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 19178808 — Surrogate Endpoint (SUR): Blood pressure
Study 25368541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12605026 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9147928 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 3975430 — Surrogate Endpoint (SUR): Blood pressure
Study 1388195 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1388195 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 4023620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24762804 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20174905 — Surrogate Endpoint (SUR): Blood pressure
Study 8828077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11791032 — Surrogate Endpoint (SUR): Blood pressure
Study 2205799 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2205799 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25616647 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25616647 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 19299777 — Surrogate Endpoint (SUR): Blood pressure
Study 14744921 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1