TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03760419 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study NCT01442935 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01442935 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT01442935 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01442935 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02757807 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT03387319 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04299230 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT00487305 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01862081 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01862081 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00473811 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00958386 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01750333 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT03417492 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT00103025 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00007956 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT00518869 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00518869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03141333 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT01951898 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03573284 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02507752 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02347436 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02384070 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT00724217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00724217 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00144144 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01527253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03024606 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study NCT01161498 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04906031 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT05007678 — Predictive Biomarker (PRD): DHODH mRNA
Genes: DHODH
Study NCT02057497 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study NCT04410510 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04410510 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00356265 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03576261 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02618486 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT01630772 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03038217 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04410159 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03316521 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT01770743 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02073162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00503425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03833154 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02797314 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05342948 — Predictive Biomarker (PRD): KDM5D mRNA
Genes: KDM5D; HY; HYA; JARID1D; KIAA0234; SMCY
Study NCT00148434 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02761408 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study NCT04496830 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03174054 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02421081 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02845063 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00773708 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT00096967 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00787033 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT03720210 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT03181763 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03181763 — Safety Biomarker (SAF): BDNF
Study NCT03181763 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03201549 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT04336241 — Predictive Biomarker (PRD): RP2 mRNA
Genes: RP2
Study NCT04336241 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03166449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03091010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03091010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00494780 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00494780 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00001304 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02264613 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02264613 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02032576 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02032576 — Safety Biomarker (SAF): BDNF
Study NCT02968472 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01147341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01471821 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00001524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02878330 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT04402957 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04402957 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03301025 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00084903 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00891930 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00891930 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00891930 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04364035 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT00661830 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00661830 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02768259 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01379014 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT00421512 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00421512 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03795649 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03795649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05741723 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT03003845 — Predictive Biomarker (PRD): S1PR1 mRNA
Genes: S1PR1; CHEDG1; EDG1
Study NCT03024424 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01147393 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT04554082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00901225 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00901225 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02433912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT03264846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03414658 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT03414658 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02713412 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04217616 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT03308812 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03377101 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03377101 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02127346 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02988817 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT00292526 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02261207 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02261207 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01377935 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02777411 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01397227 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT03521154 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03521154 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00903227 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT00003017 — Safety Biomarker (SAF): Interleukin 12
Study NCT04510454 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01576484 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00624026 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT01720550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00569855 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00208065 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT02156024 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02814422 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02814422 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02814422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02814422 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT03467256 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02379195 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04227327 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04227327 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04227327 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02644824 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT01128543 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00841035 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00841035 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04013776 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT01233024 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT02401997 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03914859 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02808585 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01353170 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01903798 — Safety Biomarker (SAF): Interleukin 1
Study NCT03943459 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT03943459 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT00866203 — Predictive Biomarker (PRD): DHDDS mRNA
Genes: DHDDS; HDS
Study NCT04414904 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT02272946 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT02272946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02272946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02272946 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT05807152 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04048135 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study NCT01677936 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01880190 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT01880190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01880190 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT01547156 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04947072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01580293 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT03185156 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01517347 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02025374 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04326218 — Predictive Biomarker (PRD): PLA2R1 mRNA
Genes: PLA2R1; CLEC13C
Study NCT04326218 — Predictive Biomarker (PRD): THSD7A mRNA
Genes: THSD7A; KIAA0960
Study NCT03047746 — Predictive Biomarker (PRD): BMF mRNA
Genes: BMF
Study NCT02073123 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT00634452 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT02389777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03204968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03277924 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT01240941 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03145480 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01720888 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01638949 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04370834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05576324 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00776451 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04558424 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03590080 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01422616 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03043768 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT04778917 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04778917 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT01544348 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03802318 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03989986 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03410966 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT03410966 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03472807 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT03472807 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT02459561 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03877003 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04062760 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00921050 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT01124734 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02508038 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00537537 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02685826 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02159625 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03529396 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT03085498 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04111705 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01035502 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study NCT01395758 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04677998 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT00524121 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00524121 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04203368 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02570542 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00548197 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03280693 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01100125 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01041417 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03226899 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02897115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00666068 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT03420742 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03420742 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT04257136 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01057537 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00644475 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03757507 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00393484 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01482195 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study NCT02307240 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02057965 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04565834 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT04565834 — Predictive Biomarker (PRD): KMO mRNA
Genes: KMO
Study NCT04565834 — Predictive Biomarker (PRD): QPRT mRNA
Genes: QPRT
Study NCT04565834 — Predictive Biomarker (PRD): IDO2 mRNA
Genes: IDO2; INDOL1
Study NCT00716924 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT02818465 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT00928213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study NCT03971175 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT01116180 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02607124 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02607124 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study NCT01118780 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03567603 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT03712930 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT01846533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00275678 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04198883 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00127881 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01355614 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT02901600 — Predictive Biomarker (PRD): DMBT1 mRNA
Genes: DMBT1; GP340
Study NCT02273102 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT02868424 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04379154 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04992156 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT04992156 — Predictive Biomarker (PRD): HR mRNA
Genes: HR