TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28933625 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 9862513 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23148500 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 23148500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21191380 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 16984797 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 9750603 — Surrogate Endpoint (SUR): Blood pressure
Study 28701596 — Surrogate Endpoint (SUR): Blood pressure
Study 24995901 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 24995901 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 24995901 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 11730260 — Surrogate Endpoint (SUR): Bone mineral density
Study 26043561 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 26043561 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 19031076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19031076 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15327407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15327407 — Surrogate Endpoint (SUR): Serum creatinine
Study 7981758 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 30185733 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 18549459 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28687 — Surrogate Endpoint (SUR): Blood pressure
Study 24583931 — Monitoring Biomarker (MOI): HBV DNA
Study 22483479 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 7033578 — Surrogate Endpoint (SUR): Blood pressure
Study 31631602 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 15866684 — Surrogate Endpoint (SUR): Serum creatinine
Study 15866684 — Surrogate Endpoint (SUR): Blood pressure
Study 15866684 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15866684 — Surrogate Endpoint (SUR): Serum testosterone
Study 10221663 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 10221663 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7759461 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7759461 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 11464260 — Surrogate Endpoint (SUR): Blood pressure
Study 11416702 — Surrogate Endpoint (SUR): Blood pressure
Study 27464593 — Surrogate Endpoint (SUR): Serum creatinine
Study 27464593 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22463698 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 28012682 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25830924 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 25830924 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8124836 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2531605 — Surrogate Endpoint (SUR): Blood pressure
Study 30261963 — Predictive Biomarker (PRD): FBN1 mRNA
Genes: FBN1; FBN
Study 17229229 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study 11665964 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 11665964 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 9680497 — Surrogate Endpoint (SUR): Blood pressure
Study 22981045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8985844 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20423913 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 16257026 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 11745931 — Monitoring Biomarker (MOI): HBV DNA
Study 9267858 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3499066 — Predictive Biomarker (PRD): PDXP mRNA
Genes: PDXP; CIN; PLP; PLPP
Study 27600061 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21190597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21190597 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 21190597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16985020 — Predictive Biomarker (PRD): MTRR mRNA
Genes: MTRR
Study 16985020 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 16985020 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 29693605 — Surrogate Endpoint (SUR): Blood pressure
Study 27208375 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27208375 — Surrogate Endpoint (SUR): Blood pressure
Study 19129749 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 17496672 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7989704 — Monitoring Biomarker (MOI): HBV DNA
Study 10813483 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 8986916 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8986916 — Surrogate Endpoint (SUR): Blood pressure
Study 31054568 — Surrogate Endpoint (SUR): Blood pressure
Study 26778006 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26778006 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 20103448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20103448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20103448 — Surrogate Endpoint (SUR): Blood pressure
Study 20103448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20103448 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20103448 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16123721 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12100762 — Surrogate Endpoint (SUR): Blood pressure
Study 29040012 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 23828112 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21138617 — Surrogate Endpoint (SUR): Blood pressure
Study 21138617 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21138617 — Surrogate Endpoint (SUR): Serum creatinine
Study 30244671 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 27729174 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10500056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10500056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21052021 — Surrogate Endpoint (SUR): Blood pressure
Study 3254831 — Surrogate Endpoint (SUR): Blood pressure
Study 18091023 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 10752681 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29678619 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22110163 — Safety Biomarker (SAF): APC
Genes: DP2; DP3; DP2.5; PPP1R46
Study 22110163 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 17846979 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 17846979 — Surrogate Endpoint (SUR): Urine free cortisol
Study 17846979 — Surrogate Endpoint (SUR): Blood pressure
Study 9678314 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28595341 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28595341 — Surrogate Endpoint (SUR): Blood pressure
Study 28595341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29557709 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29557709 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 29557709 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 20091057 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 4553613 — Surrogate Endpoint (SUR): Blood pressure
Study 25622774 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21351829 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 21351829 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 16995861 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15560538 — Surrogate Endpoint (SUR): Blood pressure
Study 9285655 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19204263 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16432273 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 9432291 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29777823 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 22537617 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22537617 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29604402 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 6664741 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 7158232 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26915841 — Surrogate Endpoint (SUR): Blood pressure
Study 2976110 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2976110 — Surrogate Endpoint (SUR): Blood pressure
Study 31822212 — Surrogate Endpoint (SUR): Bone mineral density
Study 28279368 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12955293 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 10832598 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3302150 — Surrogate Endpoint (SUR): Blood pressure
Study 31860981 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31860981 — Surrogate Endpoint (SUR): Blood pressure
Study 27799236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19485818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19485818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19485818 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28530142 — Surrogate Endpoint (SUR): Blood pressure
Study 28530142 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18492840 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 1293305 — Surrogate Endpoint (SUR): Blood pressure
Study 21532737 — Safety Biomarker (SAF): Interleukin 12
Study 9495662 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9495662 — Surrogate Endpoint (SUR): Blood pressure
Study 22552359 — Surrogate Endpoint (SUR): Serum testosterone
Study 16924568 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9075036 — Surrogate Endpoint (SUR): Blood pressure
Study 23748185 — Surrogate Endpoint (SUR): Bone mineral density
Study 16483391 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 9139168 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 9139168 — Surrogate Endpoint (SUR): Blood pressure
Study 8440356 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 20466223 — Surrogate Endpoint (SUR): Blood pressure
Study 10232312 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22938716 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 31658134 — Surrogate Endpoint (SUR): Serum creatinine
Study 31658134 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28062625 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28062625 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28062625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26440235 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15906019 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12270852 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 12270852 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 12270852 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12270852 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24373251 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 2884454 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31707498 — Predictive Biomarker (PRD): RGS4 mRNA
Genes: RGS4
Study 16935049 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10849375 — Safety Biomarker (SAF): Hypoxanthine-guanine phosphoribosyltransferase
Genes: HPRT1; HPRT
Study 19694216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19694216 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23096251 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11294048 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11294048 — Surrogate Endpoint (SUR): Blood pressure
Study 7688008 — Surrogate Endpoint (SUR): Blood pressure
Study 31608373 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29055711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9357931 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 8403788 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 6325525 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30877742 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29176386 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24671918 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 18498922 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 15711315 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12742294 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8638527 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27448700 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17283260 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2184874 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 23827078 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 23827078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23827078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11737382 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9764979 — Monitoring Biomarker (MOI): HBV DNA
Study 30058418 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30058418 — Safety Biomarker (SAF): Reactive oxygen species
Study 27401361 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 9377616 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study 2455121 — Surrogate Endpoint (SUR): Blood pressure
Study 11199329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11199329 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 11199329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17019663 — Surrogate Endpoint (SUR): Blood pressure
Study 1389517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2412041 — Surrogate Endpoint (SUR): Blood pressure
Study 31433785 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29906251 — Predictive Biomarker (PRD): SLFN11 mRNA
Genes: SLFN11
Study 29906251 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 23143762 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 14750100 — Surrogate Endpoint (SUR): Blood pressure
Study 11591234 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9702314 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7520210 — Surrogate Endpoint (SUR): Serum potassium
Study 24183196 — Surrogate Endpoint (SUR): Blood pressure
Study 22099625 — Surrogate Endpoint (SUR): Blood pressure
Study 12643410 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 2008948 — Surrogate Endpoint (SUR): Blood pressure
Study 6800869 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6800869 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22658512 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16448282 — Predictive Biomarker (PRD): PLXNB1 mRNA
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 28793772 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28793772 — Predictive Biomarker (PRD): HERPUD1 mRNA
Genes: HERPUD1; HERP; KIAA0025; MIF1
Study 19697823 — Surrogate Endpoint (SUR): Blood pressure
Study 11302274 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study 8103527 — Surrogate Endpoint (SUR): Blood pressure
Study 29735284 — Surrogate Endpoint (SUR): Blood pressure
Study 18033318 — Safety Biomarker (SAF): Human leucocyte antigen
Study 28542080 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25118999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25118999 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17339482 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 17339482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16491109 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16491109 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16491109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15488350 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26119653 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16377918 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16377918 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30701858 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 30642922 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 11908491 — Surrogate Endpoint (SUR): Bone mineral density
Study 10102784 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 19433689 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16116336 — Surrogate Endpoint (SUR): Blood pressure
Study 22742720 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22742720 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19548438 — Surrogate Endpoint (SUR): Blood pressure
Study 9655713 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 7640430 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 26269239 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 26269239 — Surrogate Endpoint (SUR): Blood pressure
Study 17349073 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 9590490 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29386007 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 16641607 — Surrogate Endpoint (SUR): Bone mineral density
Study 14640385 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1476763 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31449880 — Surrogate Endpoint (SUR): Blood pressure
Study 29330461 — Predictive Biomarker (PRD): GPR119 mRNA
Genes: GPR119
Study 29330461 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 7848788 — Surrogate Endpoint (SUR): Blood pressure
Study 3057139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7759449 — Surrogate Endpoint (SUR): Blood pressure
Study 30973544 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30973544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30973544 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15076172 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16778330 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16778330 — Surrogate Endpoint (SUR): Blood pressure
Study 11053725 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28407637 — Surrogate Endpoint (SUR): Blood pressure
Study 28407637 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 1587408 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3884409 — Surrogate Endpoint (SUR): Blood pressure
Study 3884409 — Surrogate Endpoint (SUR): Serum potassium
Study 25074984 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 23095425 — Surrogate Endpoint (SUR): Blood pressure
Study 12469706 — Surrogate Endpoint (SUR): Bone mineral density
Study 12469706 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1770568 — Surrogate Endpoint (SUR): Blood pressure
Study 25825944 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study 19265599 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 26316013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18463831 — Monitoring Biomarker (MOI): Procalcitonin
Study 20505674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20505674 — Surrogate Endpoint (SUR): Blood pressure