TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10193730 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10193730 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10193730 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10193730 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10193730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21901396 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11856085 — Surrogate Endpoint (SUR): Blood pressure
Study 7788232 — Surrogate Endpoint (SUR): Bone mineral density
Study 25463545 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21327673 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 19617815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19617815 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19617815 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26803236 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19161949 — Surrogate Endpoint (SUR): Blood pressure
Study 9495267 — Surrogate Endpoint (SUR): Blood pressure
Study 29628151 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 18175665 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 20945066 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 19114188 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16543907 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16543907 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16543907 — Surrogate Endpoint (SUR): Blood pressure
Study 12941708 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24594552 — Surrogate Endpoint (SUR): Blood pressure
Study 22001114 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28711476 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 17549472 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15995044 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 15995044 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 15995044 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25943350 — Predictive Biomarker (PRD): Hormone receptor
Study 25943350 — Surrogate Endpoint (SUR): Pathological complete response
Study 25943350 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16279294 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 16279294 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16279294 — Surrogate Endpoint (SUR): Blood pressure
Study 4064576 — Surrogate Endpoint (SUR): Blood pressure
Study 31144591 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22835498 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22835498 — Surrogate Endpoint (SUR): Blood pressure
Study 28977340 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 8698630 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 8698630 — Surrogate Endpoint (SUR): Serum creatinine
Study 31699709 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22383508 — Surrogate Endpoint (SUR): Blood pressure
Study 15390067 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 11453971 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9764996 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8158539 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1889777 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 23181455 — Surrogate Endpoint (SUR): Blood pressure
Study 22454089 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20942279 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18090872 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15950631 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 8306268 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24585202 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 15638236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11442865 — Surrogate Endpoint (SUR): Blood pressure
Study 24102986 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 20797476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20797476 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18580877 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8797128 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8797128 — Surrogate Endpoint (SUR): Blood pressure
Study 16835746 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 3219852 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 3219852 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28802628 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 28802628 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21091245 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17078213 — Surrogate Endpoint (SUR): Blood pressure
Study 26558731 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 26558731 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9927098 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7485698 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 31613055 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 11003743 — Safety Biomarker (SAF): Cardiac troponin T
Genes: TNNT2
Study 11003743 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31346789 — Surrogate Endpoint (SUR): Blood pressure
Study 17126974 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 16375203 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23395257 — Surrogate Endpoint (SUR): Serum calcium
Study 10447232 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30967640 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 23637831 — Surrogate Endpoint (SUR): Blood pressure
Study 23637831 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23637831 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30224341 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 30224341 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25879524 — Surrogate Endpoint (SUR): Blood pressure
Study 9592045 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 24150784 — Surrogate Endpoint (SUR): Blood pressure
Study 7571984 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7571984 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17403002 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 20522733 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 8970345 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 1944944 — Surrogate Endpoint (SUR): Blood pressure
Study 19760932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19760932 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 25561577 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25561577 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 9257203 — Surrogate Endpoint (SUR): Blood pressure
Study 7647223 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7647223 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 31283365 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31283365 — Surrogate Endpoint (SUR): Blood pressure
Study 24451696 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 21526889 — Predictive Biomarker (PRD): DNAAF11 mRNA
Genes: DNAAF11; LRRC6; LRTP; TSLRP
Study 7504387 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26792419 — Surrogate Endpoint (SUR): Blood pressure
Study 8881952 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24861192 — Surrogate Endpoint (SUR): Blood pressure
Study 20550533 — Surrogate Endpoint (SUR): Blood pressure
Study 16390890 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21668387 — Surrogate Endpoint (SUR): Bone mineral density
Study 19192976 — Surrogate Endpoint (SUR): Blood pressure
Study 16723303 — Surrogate Endpoint (SUR): Bone mineral density
Study 15523323 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18077795 — Surrogate Endpoint (SUR): Blood pressure
Study 18077795 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1901199 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 31532574 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 23805813 — Predictive Biomarker (PRD): PTGER3 mRNA
Genes: PTGER3
Study 24286456 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 24286456 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15992231 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12790212 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 8181027 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21054767 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21054767 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 17120180 — Surrogate Endpoint (SUR): Bone mineral density
Study 9632123 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28889724 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 22011432 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 8772586 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8772586 — Surrogate Endpoint (SUR): Blood pressure
Study 23203358 — Surrogate Endpoint (SUR): Blood pressure
Study 21047406 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21903907 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16792136 — Surrogate Endpoint (SUR): Serum calcium
Study 1729064 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20876405 — Surrogate Endpoint (SUR): Blood pressure
Study 20876405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8722438 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8722438 — Surrogate Endpoint (SUR): Blood pressure
Study 1723447 — Surrogate Endpoint (SUR): Blood pressure
Study 25017924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25017924 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 25017924 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15272511 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11603386 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 25564143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25564143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25564143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21856767 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 21856767 — Surrogate Endpoint (SUR): Serum calcium
Study 19726374 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15487709 — Safety Biomarker (SAF): Hyaluronic acid
Study 15487709 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29659967 — Predictive Biomarker (PRD): RGR mRNA
Genes: RGR
Study 16971666 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16971666 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 27903341 — Surrogate Endpoint (SUR): Blood pressure
Study 24990091 — Surrogate Endpoint (SUR): Blood pressure
Study 22048884 — Surrogate Endpoint (SUR): Blood pressure
Study 12716662 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 12716662 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12716662 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30202873 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 25765835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25765835 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25159238 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25159238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11570639 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23025273 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21403548 — Predictive Biomarker (PRD): TIFA mRNA
Genes: TIFA; T2BP
Study 21403548 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 16802483 — Surrogate Endpoint (SUR): Blood pressure
Study 3519058 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24843115 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 24843115 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 18637601 — Surrogate Endpoint (SUR): Serum methemoglobin
Study 16567825 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 12592052 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8166055 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29536284 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23980734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18199920 — Surrogate Endpoint (SUR): Blood pressure
Study 12750250 — Predictive Biomarker (PRD): NOCT mRNA
Genes: NOCT; CCR4; CCRN4L; NOC
Study 10893688 — Surrogate Endpoint (SUR): Bone mineral density
Study 31517759 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 17216681 — Surrogate Endpoint (SUR): Bone mineral density
Study 9562222 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30660443 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 21870317 — Safety Biomarker (SAF): Cytochrome c
Study 12227482 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 2644531 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7890006 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7890006 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7656926 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 351570 — Surrogate Endpoint (SUR): Blood pressure
Study 25542416 — Surrogate Endpoint (SUR): Blood pressure
Study 23884017 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 29183347 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 14990633 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7539182 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 336306 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30820962 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27326658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27326658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14621837 — Surrogate Endpoint (SUR): Serum creatinine
Study 22303706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9294121 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 3011530 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23117133 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 23117133 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15902990 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 15155715 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 28145413 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21054216 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11506058 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11506058 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30545915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 30545915 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30545915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25702095 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25639139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31001997 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 24352294 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 21195592 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11923036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11923036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26529006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20689328 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20689328 — Surrogate Endpoint (SUR): Serum calcium
Study 20689328 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 19801040 — Surrogate Endpoint (SUR): Blood pressure
Study 15644572 — Surrogate Endpoint (SUR): Blood pressure
Study 3038722 — Monitoring Biomarker (MOI): HBV DNA
Study 29717197 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 29717197 — Predictive Biomarker (PRD): KLB mRNA
Genes: KLB
Study 29717197 — Predictive Biomarker (PRD): FGFR4 mRNA
Genes: FGFR4; JTK2; TKF
Study 16008071 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 2288833 — Surrogate Endpoint (SUR): Blood pressure
Study 14675406 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 14675406 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31638433 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 31638433 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24000874 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17081832 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17081832 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19942303 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19942303 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 19942303 — Surrogate Endpoint (SUR): Blood pressure
Study 19629514 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9738637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2856543 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 23546631 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 12794835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12794835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24281981 — Surrogate Endpoint (SUR): Blood pressure
Study 18478481 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study 12496528 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10910855 — Surrogate Endpoint (SUR): Blood pressure
Study 1381018 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 1381018 — Surrogate Endpoint (SUR): Blood pressure
Study 1381018 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6347498 — Surrogate Endpoint (SUR): Blood pressure
Study 24144212 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 8636753 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31504908 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29701621 — Safety Biomarker (SAF): Hyaluronic acid
Study 8847680 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31802692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31802692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31802692 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31802692 — Safety Biomarker (SAF): IL-6 and IL-10
Study 26324406 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 26324406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19791830 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19791830 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9143084 — Surrogate Endpoint (SUR): Bone mineral density
Study 3539306 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 22538270 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 10373752 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 27176122 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS