TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15314975 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 15314975 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8457082 — Surrogate Endpoint (SUR): Blood pressure
Study 2569214 — Surrogate Endpoint (SUR): Blood pressure
Study 31234376 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 31234376 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31234376 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25105516 — Predictive Biomarker (PRD): ISG15 mRNA
Genes: ISG15; G1P2; UCRP
Study 19231325 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31014147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31014147 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31014147 — Safety Biomarker (SAF): BDNF
Study 11343045 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17081405 — Surrogate Endpoint (SUR): Blood pressure
Study 12824787 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10825337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10825337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8677193 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1725027 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1725027 — Surrogate Endpoint (SUR): Blood pressure
Study 31027098 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2473061 — Safety Biomarker (SAF): Interleukin 1
Study 31121331 — Safety Biomarker (SAF): Hyaluronic acid
Study 21227013 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 21227013 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15526507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31791376 — Surrogate Endpoint (SUR): Blood pressure
Study 29986900 — Surrogate Endpoint (SUR): Blood pressure
Study 20375338 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 10418585 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 10418585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10418585 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10418585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1693065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26463242 — Predictive Biomarker (PRD): NCOA2 mRNA
Genes: NCOA2; BHLHE75; SRC2; TIF2
Study 23615131 — Monitoring Biomarker (MOI): HBV DNA
Study 19808840 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 19808840 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 7953882 — Surrogate Endpoint (SUR): Blood pressure
Study 27418629 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 27418629 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 27418629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27418629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27418629 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 27418629 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 19142373 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 19142373 — Surrogate Endpoint (SUR): Blood pressure
Study 16608440 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25183687 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21693037 — Surrogate Endpoint (SUR): Bone mineral density
Study 18507668 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14615107 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14615107 — Surrogate Endpoint (SUR): Blood pressure
Study 30823930 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24999004 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 30412479 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 25223231 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21272194 — Surrogate Endpoint (SUR): Blood pressure
Study 14722642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14722642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28302155 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28302155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28302155 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 28302155 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25750280 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25750280 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 16604476 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 7018846 — Surrogate Endpoint (SUR): Blood pressure
Study 31672469 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31245886 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23695205 — Safety Biomarker (SAF): MTHFR
Study 23695205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10363683 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31813230 — Safety Biomarker (SAF): GAT1
Genes: SLC6A1; GABATR; GABATHG; GAT-1; hGAT-1
Study 27893182 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 27893182 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21514308 — Surrogate Endpoint (SUR): Blood pressure
Study 11703862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11703862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29540274 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26717881 — Surrogate Endpoint (SUR): Blood pressure
Study 23095194 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29773176 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29773176 — Surrogate Endpoint (SUR): Blood pressure
Study 29773176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26854810 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 26854810 — Surrogate Endpoint (SUR): Bone mineral density
Study 15857076 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12423714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12423714 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12423714 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10412786 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10412786 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30959123 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26916483 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24968790 — Surrogate Endpoint (SUR): Serum calcium
Study 20703158 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 20703158 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31757470 — Surrogate Endpoint (SUR): Blood pressure
Study 31181973 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 16965740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16965740 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16965740 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9290168 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8497820 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29520080 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24704421 — Surrogate Endpoint (SUR): Blood pressure
Study 18790817 — Safety Biomarker (SAF): MTHFR
Study 11074805 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8826949 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1576060 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 3930437 — Safety Biomarker (SAF): 51Cr-EDTA
Study 7719242 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7719242 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7719242 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 7719242 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24997351 — Predictive Biomarker (PRD): ADRA2B mRNA
Genes: ADRA2B; ADRA2L1; ADRA2RL1
Study 21171297 — Safety Biomarker (SAF): Th2 cell
Study 9613780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24101768 — Surrogate Endpoint (SUR): Blood pressure
Study 18460557 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 16434984 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 16434984 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16434984 — Safety Biomarker (SAF): Reactive oxygen species
Study 19065902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9048259 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9048259 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16093520 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 30621529 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 29231472 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 10768912 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24833688 — Surrogate Endpoint (SUR): Blood pressure
Study 24833688 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12432322 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 1776410 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1776410 — Surrogate Endpoint (SUR): Blood pressure
Study 26194253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26194253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26194253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24400643 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 616215 — Surrogate Endpoint (SUR): Blood pressure
Study 27913872 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27913872 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24065423 — Safety Biomarker (SAF): Reactive oxygen species
Study 22641239 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 22641239 — Surrogate Endpoint (SUR): Bone mineral density
Study 20554607 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 27879359 — Surrogate Endpoint (SUR): Blood pressure
Study 10762286 — Safety Biomarker (SAF): DRD2
Study 30669022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24698199 — Surrogate Endpoint (SUR): Blood pressure
Study 24698199 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22759069 — Predictive Biomarker (PRD): RIT1 mRNA
Genes: RIT1; RIBB; RIT; ROC1
Study 22250141 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21190551 — Predictive Biomarker (PRD): NDUFV2 mRNA
Genes: NDUFV2
Study 27631883 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27631883 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25624376 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18509181 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 18509181 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 18509181 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18509181 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 18509181 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 18509181 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 18509181 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 18509181 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 18509181 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 14520110 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21907861 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16714425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2975609 — Surrogate Endpoint (SUR): Blood pressure
Study 2975609 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29695707 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 1383416 — Monitoring Biomarker (MOI): HBV DNA
Study 31211741 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30112584 — Surrogate Endpoint (SUR): Blood pressure
Study 26946077 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 26946077 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26946077 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26876066 — Surrogate Endpoint (SUR): Blood pressure
Study 22399096 — Surrogate Endpoint (SUR): Blood pressure
Study 22399096 — Surrogate Endpoint (SUR): Serum uric acid
Study 8756388 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 22377561 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15896427 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15896427 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 26176313 — Surrogate Endpoint (SUR): Serum creatinine
Study 21828378 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21828378 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28237253 — Safety Biomarker (SAF): Hyaluronic acid
Study 26247661 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 21110180 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16575715 — Surrogate Endpoint (SUR): Blood pressure
Study 29080928 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 24918560 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 18261195 — Surrogate Endpoint (SUR): Blood pressure
Study 30293937 — Surrogate Endpoint (SUR): Blood pressure
Study 30293937 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19958982 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 11549652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7932018 — Surrogate Endpoint (SUR): Probing pocket depth
Study 28224367 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25128049 — Predictive Biomarker (PRD): LGSN mRNA
Genes: LGSN; GLULD1; LGS
Study 11570432 — Surrogate Endpoint (SUR): Blood pressure
Study 10036794 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 10036794 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10036794 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31638341 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 26646596 — Surrogate Endpoint (SUR): Blood pressure
Study 24834493 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28867601 — Surrogate Endpoint (SUR): Blood pressure
Study 11938856 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31985725 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12933575 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20212271 — Surrogate Endpoint (SUR): Blood pressure
Study 17564952 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 15735660 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 10081035 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 7752627 — Surrogate Endpoint (SUR): Blood pressure
Study 28209636 — Surrogate Endpoint (SUR): Blood pressure
Study 28209636 — Surrogate Endpoint (SUR): Serum creatinine
Study 23863676 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 26044576 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 23582353 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23582353 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 20570559 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20570559 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 20570559 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20570559 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18180976 — Surrogate Endpoint (SUR): Bone mineral density
Study 18093252 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18093252 — Surrogate Endpoint (SUR): Blood pressure
Study 31144432 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31144432 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 26858430 — Surrogate Endpoint (SUR): Blood pressure
Study 26858430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26858430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26858430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19920098 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15201372 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 843418 — Surrogate Endpoint (SUR): Blood pressure
Study 19644190 — Surrogate Endpoint (SUR): Blood pressure
Study 15388510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12196773 — Surrogate Endpoint (SUR): Blood pressure
Study 2673511 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19925045 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19925045 — Surrogate Endpoint (SUR): Blood pressure
Study 19523047 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 19523047 — Predictive Biomarker (PRD): GABRB2 mRNA
Genes: GABRB2
Study 17726365 — Surrogate Endpoint (SUR): Bone mineral density
Study 23797006 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 14992738 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7956623 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 29133566 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 2052467 — Surrogate Endpoint (SUR): Blood pressure
Study 25293966 — Surrogate Endpoint (SUR): Blood pressure
Study 19848201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19848201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15665959 — Safety Biomarker (SAF): Cytochrome c
Study 2451930 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 2451930 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2451930 — Surrogate Endpoint (SUR): Blood pressure
Study 25951755 — Surrogate Endpoint (SUR): Blood pressure
Study 15121563 — Surrogate Endpoint (SUR): Bone mineral density
Study 11273796 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9509441 — Surrogate Endpoint (SUR): Blood pressure
Study 913230 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 28490529 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 28490529 — Surrogate Endpoint (SUR): Blood pressure
Study 24921623 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23505168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23505168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23505168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1996571 — Surrogate Endpoint (SUR): Serum creatinine
Study 6662170 — Surrogate Endpoint (SUR): Blood pressure
Study 31318033 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31318033 — Surrogate Endpoint (SUR): Blood pressure
Study 28240186 — Surrogate Endpoint (SUR): Blood pressure
Study 11083272 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8653991 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 6398982 — Surrogate Endpoint (SUR): Blood pressure