TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01077648 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03417674 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01131208 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT04030728 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04030728 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00365456 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01925573 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01925573 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02071082 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02048072 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02520687 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04176354 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04176354 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03011268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01540253 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00441974 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02085369 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study NCT02085369 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03205761 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03205761 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02522676 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT02522676 — Safety Biomarker (SAF): Netrin-1
Genes: NTN1; NTN1L
Study NCT05281107 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT01541189 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03655795 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02730585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01971723 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT01796197 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01007331 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03803514 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02380573 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT04643990 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04643990 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00881803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04185753 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03747211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02127671 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00986609 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT00513578 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02843529 — Predictive Biomarker (PRD): NMI mRNA
Genes: NMI
Study NCT03169764 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00995475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00995475 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT04044950 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02800070 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02800070 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT03995368 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT01502293 — Safety Biomarker (SAF): Interleukin 12
Study NCT04768738 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03557749 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT03160261 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00003149 — Safety Biomarker (SAF): Interleukin 12
Study NCT06183762 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00775840 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02305095 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study NCT01833611 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02208661 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT01617824 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01391962 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01391962 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04291781 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01513109 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT02361541 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03815929 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03114826 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00005221 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00627653 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT04437927 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03687567 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study NCT00481052 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00481052 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02572674 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02374099 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02374099 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03774654 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT02898181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02898181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02898181 — Safety Biomarker (SAF): Interleukin 1
Study NCT02898181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02898181 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT02898181 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT02284789 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT02800278 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03227471 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03227471 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study NCT04714242 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00861120 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00203359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03871777 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01227122 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04229537 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT04419610 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03765840 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03765840 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study NCT03587961 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03366688 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03366688 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04363528 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03789942 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00791362 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00054704 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03118700 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00612950 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02633462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04660461 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study NCT00549939 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study NCT02490475 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00603460 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT00139282 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02902354 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01613898 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study NCT01613898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03533972 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT03533972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03533972 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03533972 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT02057874 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT05063721 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT00721370 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT00752843 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02943850 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study NCT04565886 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT01104038 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00143663 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03049774 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study NCT04344782 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03428763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00005757 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03221751 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00131469 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01664988 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04424862 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00289887 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00243386 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT06604650 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01618201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00454103 — Safety Biomarker (SAF): CYP11B1 mRNA
Genes: CYP11B1; S11BH
Study NCT00058812 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03913052 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02958020 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02336659 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02336659 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT03382964 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04364802 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04535674 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02579954 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00444691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00253643 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study NCT01431196 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03387735 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00164112 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT00164112 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00164112 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00164112 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00975338 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT03488368 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03488368 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03313388 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04088890 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT04503213 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study NCT01939470 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01939470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01939470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04338009 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04338009 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02839265 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02580708 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00948363 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04158076 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00778128 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT02159703 — Predictive Biomarker (PRD): SERPINB3 mRNA
Genes: SERPINB3; SCCA; SCCA1
Study NCT05190250 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study NCT05190250 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study NCT05190250 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT04529499 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00861731 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02330978 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01614626 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT01614626 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04968977 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT04390074 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04116086 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00501124 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04670497 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02554747 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02592551 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01692210 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00971165 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02967081 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT03015675 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04522765 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04641767 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study NCT02956954 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT00402649 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study NCT03264404 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT00522145 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00522145 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01465100 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04628637 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study NCT02224716 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study NCT01330368 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00126490 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03837067 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03837067 — Safety Biomarker (SAF): DRD2
Study NCT01592292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03476629 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01125709 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04372836 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02311205 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT02445313 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02225730 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT02640833 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02285569 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01624857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02527759 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04410900 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00843388 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04469465 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT01010880 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT01010880 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02859220 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT02116348 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT01671111 — Predictive Biomarker (PRD): Liver iron
Study NCT01852877 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00530270 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00039585 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT03238885 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT03085095 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT03646461 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04412200 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01328951 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01328951 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03140527 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00262184 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04385277 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02162836 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03295877 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01390272 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03525717 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03096951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00841568 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT04178694 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06433492 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00379795 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04960982 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT01857284 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT04182100 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT00914849 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01995708 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT02102217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00948298 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00091104 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03415139 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT01567657 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00248755 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT04721470 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT01252745 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT04227899 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT02802748 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02802748 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02802748 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00336024 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT01666431 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01666431 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01666431 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03433313 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01294202 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT00846300 — Surrogate Endpoint (SUR): Blood pressure