TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18952211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21036889 — Surrogate Endpoint (SUR): Serum creatinine
Study 8952810 — Surrogate Endpoint (SUR): Blood pressure
Study 25025854 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 20801567 — Surrogate Endpoint (SUR): Serum creatinine
Study 20801567 — Surrogate Endpoint (SUR): Blood pressure
Study 27626136 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15564721 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 8747407 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 2233115 — Surrogate Endpoint (SUR): Blood pressure
Study 15226683 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 15226683 — Safety Biomarker (SAF): Interleukin 1
Study 15226683 — Safety Biomarker (SAF): Hyaluronic acid
Study 9684909 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9684909 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 31226684 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 29157765 — Surrogate Endpoint (SUR): Blood pressure
Study 12421482 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7854376 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24915175 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18085138 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 14967451 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30707138 — Surrogate Endpoint (SUR): Blood pressure
Study 27004462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27004462 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17673811 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 29982728 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 14521597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2442543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2442543 — Surrogate Endpoint (SUR): Blood pressure
Study 27321596 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 27321596 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 27321596 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27321596 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23873670 — Surrogate Endpoint (SUR): Bone mineral density
Study 19762071 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17684522 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15968885 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15968885 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 11307227 — Predictive Biomarker (PRD): TP53INP1 mRNA
Genes: TP53INP1; P53DINP1; SIP
Study 8402734 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16507374 — Surrogate Endpoint (SUR): Serum uric acid
Study 10593375 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10593375 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28028984 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25493120 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21655909 — Predictive Biomarker (PRD): NANOS1 mRNA
Genes: NANOS1; NOS1
Study 21655909 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 21655909 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21655909 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 11862965 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7617349 — Surrogate Endpoint (SUR): Blood pressure
Study 334315 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31385001 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 19188550 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26254752 — Surrogate Endpoint (SUR): Blood pressure
Study 20701479 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 15030300 — Safety Biomarker (SAF): Reactive oxygen species
Study 22674470 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 23958264 — Surrogate Endpoint (SUR): Blood pressure
Study 17416453 — Surrogate Endpoint (SUR): Serum sodium
Study 9699568 — Surrogate Endpoint (SUR): Blood pressure
Study 2760214 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 20971975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9726444 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15514193 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8497284 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28859868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28859868 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16446313 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30298556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24962875 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 27368672 — Safety Biomarker (SAF): Sodium/hydrogen exchanger 3
Genes: SLC9A3; NHE3
Study 26574871 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26574871 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 26574871 — Surrogate Endpoint (SUR): Blood pressure
Study 19034332 — Surrogate Endpoint (SUR): Blood pressure
Study 16819567 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 16819567 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14600515 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10898421 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8882962 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28026777 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 16948861 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9139271 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 9139271 — Predictive Biomarker (PRD): HES1 mRNA
Genes: HES1; BHLHB39; HL; HRY
Study 6291832 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6291832 — Surrogate Endpoint (SUR): Blood pressure
Study 28581397 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 21925996 — Surrogate Endpoint (SUR): Blood pressure
Study 22768174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19180484 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 21944697 — Surrogate Endpoint (SUR): Blood pressure
Study 19583930 — Surrogate Endpoint (SUR): Blood pressure
Study 8311599 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31574878 — Monitoring Biomarker (MOI): Procalcitonin
Study 27789297 — Predictive Biomarker (PRD): M6PR mRNA
Genes: M6PR; MPR46; MPRD
Study 11434165 — Safety Biomarker (SAF): Reactive oxygen species
Study 8299318 — Surrogate Endpoint (SUR): Blood pressure
Study 31670603 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 11522187 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11522187 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11192866 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 11192866 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9452280 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 30443924 — Surrogate Endpoint (SUR): Blood pressure
Study 6294699 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 10587334 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9193426 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30037778 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26540028 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11783322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31857431 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study 26841085 — Surrogate Endpoint (SUR): Bone mineral density
Study 23782950 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23782950 — Predictive Biomarker (PRD): Hormone receptor
Study 16772525 — Surrogate Endpoint (SUR): Blood pressure
Study 9366499 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18227177 — Surrogate Endpoint (SUR): Serum creatinine
Study 6361988 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 3382764 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30467695 — Surrogate Endpoint (SUR): Serum creatinine
Study 28460246 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 15539971 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18242413 — Surrogate Endpoint (SUR): Platelet count response
Study 10199862 — Surrogate Endpoint (SUR): Blood pressure
Study 20671 — Surrogate Endpoint (SUR): Blood pressure
Study 30239421 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21677052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19434759 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 1620810 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1620810 — Surrogate Endpoint (SUR): Blood pressure
Study 24760382 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16250265 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 16250265 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 16250265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12020980 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12020980 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26874974 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24182347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24182347 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study 22373720 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 20560112 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 10470387 — Surrogate Endpoint (SUR): Blood pressure
Study 31274187 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31274187 — Surrogate Endpoint (SUR): Serum creatinine
Study 31274187 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25756064 — Predictive Biomarker (PRD): DOCK3 mRNA
Genes: DOCK3; KIAA0299; MOCA
Study 11248761 — Surrogate Endpoint (SUR): Blood pressure
Study 7750598 — Surrogate Endpoint (SUR): Sperm parameters
Study 27866454 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 25412116 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 25412116 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19188184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19188184 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23003916 — Predictive Biomarker (PRD): MCF2 mRNA
Genes: MCF2; DBL
Study 21300712 — Surrogate Endpoint (SUR): Blood pressure
Study 8404115 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2957569 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28306636 — Surrogate Endpoint (SUR): Blood pressure
Study 15888038 — Surrogate Endpoint (SUR): Serum creatinine
Study 12218418 — Surrogate Endpoint (SUR): Blood pressure
Study 30284018 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24615047 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 19650674 — Surrogate Endpoint (SUR): Serum potassium
Study 29379143 — Surrogate Endpoint (SUR): Blood pressure
Study 15860237 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15860237 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 19939373 — Safety Biomarker (SAF): Hyaluronic acid
Study 18540734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15846228 — Surrogate Endpoint (SUR): Bone mineral density
Study 23706048 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20102772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20102772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9495222 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8053737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8053737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19284663 — Surrogate Endpoint (SUR): Blood pressure
Study 27622998 — Surrogate Endpoint (SUR): Serum sodium
Study 19361872 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 18287162 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8403911 — Safety Biomarker (SAF): Reactive oxygen species
Study 20449532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 6137327 — Surrogate Endpoint (SUR): Blood pressure
Study 6137327 — Surrogate Endpoint (SUR): Serum potassium
Study 6137327 — Surrogate Endpoint (SUR): Serum uric acid
Study 24769332 — Surrogate Endpoint (SUR): Serum calcium
Study 21701082 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21701082 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 21701082 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 17470830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11510062 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9669006 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26420199 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 17208334 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 12460519 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7700763 — Surrogate Endpoint (SUR): Blood pressure
Study 2199618 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 276963 — Surrogate Endpoint (SUR): Blood pressure
Study 31112273 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 31112273 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31112273 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study 31112273 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 31112273 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 31112273 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 31112273 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 31112273 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 31112273 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 31112273 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 31112273 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 24337619 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23891702 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 23891702 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 23891702 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23891702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8334344 — Predictive Biomarker (PRD): NELFE mRNA
Genes: NELFE; RD; RDBP
Study 28470563 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26114234 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 20838991 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15596636 — Surrogate Endpoint (SUR): Serum creatinine
Study 15596636 — Surrogate Endpoint (SUR): Serum uric acid
Study 11387278 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 11387278 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11387278 — Safety Biomarker (SAF): Reactive oxygen species
Study 30993934 — Surrogate Endpoint (SUR): Serum creatinine
Study 28422346 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28422346 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28422346 — Surrogate Endpoint (SUR): Blood pressure
Study 16510122 — Safety Biomarker (SAF): XRCC1
Genes: RCC
Study 16510122 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 16510122 — Predictive Biomarker (PRD): XRCC3 mRNA
Genes: XRCC3
Study 3085261 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3085261 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11558795 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 29986023 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 29986023 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 29986023 — Safety Biomarker (SAF): Cytochrome c
Study 20950476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12419297 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12419297 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17526862 — Surrogate Endpoint (SUR): Hematologic response
Study 26372487 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16875796 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31450964 — Surrogate Endpoint (SUR): Blood pressure
Study 23226426 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23226426 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23226426 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17539738 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 15610365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 10845823 — Surrogate Endpoint (SUR): Blood pressure
Study 3545686 — Surrogate Endpoint (SUR): Blood pressure
Study 22803404 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22803404 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18036290 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 18036290 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28209624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23609792 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23609792 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9256120 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 30282375 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 16408674 — Surrogate Endpoint (SUR): Blood pressure
Study 29020174 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 29020174 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26194691 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26194691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26194691 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15289960 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8088691 — Surrogate Endpoint (SUR): Blood pressure
Study 26844764 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9369422 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 9369422 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 9369422 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 8239585 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7967425 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25792808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25792808 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17084257 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17084257 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9741608 — Surrogate Endpoint (SUR): Blood pressure
Study 3132853 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20175801 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31155698 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 11386927 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7837160 — Surrogate Endpoint (SUR): Bone mineral density