TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28540893 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17000354 — Predictive Biomarker (PRD): PNOC mRNA
Genes: PNOC; OFQ
Study 10884864 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30127143 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 30127143 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12003435 — Surrogate Endpoint (SUR): Bone mineral density
Study 27236344 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 22730693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24953015 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19568208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19568208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12569977 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12569977 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 793848 — Surrogate Endpoint (SUR): Blood pressure
Study 21838410 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 21838410 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 11497193 — Surrogate Endpoint (SUR): Blood pressure
Study 30267738 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30267738 — Predictive Biomarker (PRD): GCLC mRNA
Genes: GCLC; GLCL; GLCLC
Study 30267738 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10654498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10654498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10654498 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 10654498 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2582828 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27939230 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27939230 — Surrogate Endpoint (SUR): Blood pressure
Study 20137285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20689320 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19938906 — Predictive Biomarker (PRD): CDK7 mRNA
Genes: CDK7; CAK; CAK1; CDKN7; MO15; STK1
Study 19938906 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 25846350 — Surrogate Endpoint (SUR): Blood pressure
Study 3071459 — Surrogate Endpoint (SUR): Blood pressure
Study 29714034 — Surrogate Endpoint (SUR): Blood pressure
Study 24825515 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24825515 — Surrogate Endpoint (SUR): Serum creatinine
Study 15635344 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15635344 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30773497 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 21569165 — Predictive Biomarker (PRD): TCP1 mRNA
Genes: TCP1; CCT1; CCTA
Study 12603251 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27316778 — Predictive Biomarker (PRD): CRNN mRNA
Genes: CRNN; C1orf10; DRC1; PDRC1; SEP53
Study 27316778 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 15071260 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19723906 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 17703139 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29192741 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 27517517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27517517 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 27517517 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 6131164 — Surrogate Endpoint (SUR): Blood pressure
Study 19190916 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 2666139 — Surrogate Endpoint (SUR): Blood pressure
Study 201593 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29548285 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 27815344 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 29584548 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 23046564 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 23046564 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23046564 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 23046564 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 19890271 — Surrogate Endpoint (SUR): Serum creatinine
Study 12147537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12147537 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12147537 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15201942 — Safety Biomarker (SAF): Interleukin 1
Study 8266382 — Surrogate Endpoint (SUR): Blood pressure
Study 3307521 — Surrogate Endpoint (SUR): Blood pressure
Study 23733095 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 12536506 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 9403579 — Surrogate Endpoint (SUR): Blood pressure
Study 3315677 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31915153 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28601965 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 12827403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12827403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11523062 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9190554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26571496 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8755850 — Predictive Biomarker (PRD): INSR mRNA
Genes: INSR
Study 30661488 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30661488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28446500 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 26694596 — Surrogate Endpoint (SUR): Bone mineral density
Study 25212703 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17713157 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 17713157 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 9758732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9758732 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9758732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28603098 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 17121873 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 17121873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17121873 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30676635 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30676635 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29953876 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 29953876 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25764376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25764376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16426959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16426959 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7033947 — Surrogate Endpoint (SUR): Blood pressure
Study 18985374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17891560 — Surrogate Endpoint (SUR): Blood pressure
Study 25947301 — Surrogate Endpoint (SUR): Blood pressure
Study 24135599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21711517 — Surrogate Endpoint (SUR): Blood pressure
Study 10966240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10966240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10966240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10966240 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6219578 — Surrogate Endpoint (SUR): Serum calcium
Study 30538099 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A1 mRNA
Genes: SRD5A1
Study 20879853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15077082 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7956625 — Surrogate Endpoint (SUR): Blood pressure
Study 31941544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23175674 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23175674 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18791486 — Surrogate Endpoint (SUR): Bone mineral density
Study 16773412 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 10597759 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10597759 — Surrogate Endpoint (SUR): Blood pressure
Study 26332193 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 20473736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20473736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18322252 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 18322252 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 6994764 — Surrogate Endpoint (SUR): Blood pressure
Study 27454856 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10248157 — Surrogate Endpoint (SUR): Blood pressure
Study 17135639 — Predictive Biomarker (PRD): Hormone receptor
Study 11104591 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8513849 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8513849 — Surrogate Endpoint (SUR): Blood pressure
Study 16540710 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24185212 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24185212 — Surrogate Endpoint (SUR): Blood pressure
Study 22085595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22085595 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 18595975 — Surrogate Endpoint (SUR): Bone mineral density
Study 31384878 — Predictive Biomarker (PRD): USP9X mRNA
Genes: USP9X; DFFRX; FAM; USP9
Study 20426644 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25393622 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18953854 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18953854 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18953854 — Surrogate Endpoint (SUR): Blood pressure
Study 8875970 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1725202 — Surrogate Endpoint (SUR): Blood pressure
Study 7200722 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7200722 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26293682 — Surrogate Endpoint (SUR): Bone mineral density
Study 24643055 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21138499 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16150550 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 2865721 — Surrogate Endpoint (SUR): Blood pressure
Study 23907995 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 9347433 — Surrogate Endpoint (SUR): Blood pressure
Study 3440987 — Surrogate Endpoint (SUR): Blood pressure
Study 29944308 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 22529301 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7034161 — Surrogate Endpoint (SUR): Serum testosterone
Study 17520791 — Predictive Biomarker (PRD): SCARA3 mRNA
Genes: SCARA3; CSR
Study 17520791 — Predictive Biomarker (PRD): PPP1R13L mRNA
Genes: PPP1R13L; IASPP; NKIP1; PPP1R13BL; RAI
Study 17466593 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9034269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 3554943 — Surrogate Endpoint (SUR): Blood pressure
Study 11056241 — Surrogate Endpoint (SUR): Bone mineral density
Study 30137193 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 30137193 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 30137193 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27437913 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 3743153 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18672629 — Surrogate Endpoint (SUR): Blood pressure
Study 27868366 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25336730 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 19295955 — Surrogate Endpoint (SUR): Serum sodium
Study 17077623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17077623 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17077623 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 17077623 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17077623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29438682 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21390318 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 18309945 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 17136298 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 6860527 — Surrogate Endpoint (SUR): Blood pressure
Study 18848176 — Surrogate Endpoint (SUR): Blood pressure
Study 7127998 — Surrogate Endpoint (SUR): Blood pressure
Study 7127998 — Surrogate Endpoint (SUR): Serum potassium
Study 9585310 — Surrogate Endpoint (SUR): Blood pressure
Study 2719293 — Surrogate Endpoint (SUR): Blood pressure
Study 23358971 — Predictive Biomarker (PRD): Hormone receptor
Study 16840386 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10709792 — Surrogate Endpoint (SUR): Blood pressure
Study 8221740 — Surrogate Endpoint (SUR): Blood pressure
Study 12947437 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12947437 — Surrogate Endpoint (SUR): Blood pressure
Study 31916533 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30593551 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 30593551 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 30593551 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30593551 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 30593551 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24984177 — Surrogate Endpoint (SUR): Blood pressure
Study 12475578 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 30920117 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 31156913 — Surrogate Endpoint (SUR): Blood pressure
Study 15311146 — Surrogate Endpoint (SUR): Blood pressure
Study 1979615 — Surrogate Endpoint (SUR): Blood pressure
Study 30885012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30885012 — Monitoring Biomarker (MOI): Procalcitonin
Study 30885012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30885012 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30885012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30885012 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26491122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26491122 — Surrogate Endpoint (SUR): Blood pressure
Study 23382975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21620765 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 18081728 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 9195694 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31222586 — Surrogate Endpoint (SUR): Blood pressure
Study 28392340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28392340 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28392340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28392340 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28392340 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23332680 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 16817277 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16817277 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16817277 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9110115 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9110115 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1530434 — Surrogate Endpoint (SUR): Blood pressure
Study 31410465 — Predictive Biomarker (PRD): XPC mRNA
Genes: XPC; XPCC
Study 31410465 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 18029326 — Surrogate Endpoint (SUR): Blood pressure
Study 25134779 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 16924565 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9129851 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9129851 — Surrogate Endpoint (SUR): Blood pressure
Study 23434724 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 10840174 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 17324976 — Surrogate Endpoint (SUR): Blood pressure
Study 7805711 — Surrogate Endpoint (SUR): Serum testosterone
Study 30980691 — Surrogate Endpoint (SUR): Blood pressure
Study 23354313 — Surrogate Endpoint (SUR): Blood pressure
Study 15562200 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 6991095 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17762738 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 17762738 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31650255 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 31650255 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 11230288 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7968419 — Predictive Biomarker (PRD): MAP3K14 mRNA
Genes: MAP3K14; NIK
Study 7968419 — Predictive Biomarker (PRD): INVS mRNA
Genes: INVS; INV; NPHP2
Study 2889391 — Surrogate Endpoint (SUR): Blood pressure
Study 12750879 — Surrogate Endpoint (SUR): Bone mineral density
Study 10531155 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 25222001 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 25222001 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 19651277 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19651277 — Surrogate Endpoint (SUR): Blood pressure
Study 3793849 — Surrogate Endpoint (SUR): Serum testosterone
Study 30559106 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30559106 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 26100557 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 24952855 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9535416 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11802678 — Surrogate Endpoint (SUR): Blood pressure