TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31027457 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24858870 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 24858870 — Predictive Biomarker (PRD): DSE mRNA
Genes: DSE; SART2
Study 22067410 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 22067410 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 22067410 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9815203 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7813605 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 2700321 — Surrogate Endpoint (SUR): Blood pressure
Study 30955978 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 30955978 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28525305 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 28525305 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 28525305 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 23187956 — Surrogate Endpoint (SUR): Blood pressure
Study 23187956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23187956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23187956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23187956 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16530578 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 3332119 — Surrogate Endpoint (SUR): Serum creatinine
Study 29306057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29306057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12139873 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31044748 — Monitoring Biomarker (MOI): HBV DNA
Study 30616740 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 30616740 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 18842668 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 3311119 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25615445 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 6423063 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27049176 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27049176 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27049176 — Surrogate Endpoint (SUR): Serum creatinine
Study 22377540 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20350990 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8622076 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24657555 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24657555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17319791 — Surrogate Endpoint (SUR): Blood pressure
Study 3094355 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3094355 — Surrogate Endpoint (SUR): Blood pressure
Study 10382190 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study 8730971 — Surrogate Endpoint (SUR): Blood pressure
Study 23360820 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 18025996 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 7737631 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19690618 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 9041214 — Surrogate Endpoint (SUR): Blood pressure
Study 9041214 — Surrogate Endpoint (SUR): Serum sodium
Study 26061222 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 23884332 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 12324677 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12324677 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 8963481 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 18421281 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 18421281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18421281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18421281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12640069 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29617523 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26721833 — Predictive Biomarker (PRD): HDGFL2 mRNA
Genes: HDGFL2; HDGF2; HDGFRP2; HRP2; UNQ785/PRO1604
Study 10571797 — Surrogate Endpoint (SUR): Serum uric acid
Study 1428437 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20473737 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20473737 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20473737 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14990557 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25727860 — Surrogate Endpoint (SUR): Serum creatinine
Study 22048712 — Surrogate Endpoint (SUR): Blood pressure
Study 11379675 — Surrogate Endpoint (SUR): Blood pressure
Study 3606929 — Surrogate Endpoint (SUR): Blood pressure
Study 23988791 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23988791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23988791 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 15481651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10343151 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 10343151 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 7498102 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 18533934 — Surrogate Endpoint (SUR): Bone mineral density
Study 9715775 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9715775 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 28472101 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14999204 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11707555 — Surrogate Endpoint (SUR): Blood pressure
Study 14605518 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10394887 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26164864 — Surrogate Endpoint (SUR): Blood pressure
Study 26164864 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23657083 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23657083 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 23657083 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19628934 — Surrogate Endpoint (SUR): Blood pressure
Study 29650764 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 29650764 — Predictive Biomarker (PRD): SNN mRNA
Genes: SNN
Study 29650764 — Predictive Biomarker (PRD): TXNDC11 mRNA
Genes: TXNDC11; EFP1
Study 29650764 — Predictive Biomarker (PRD): CHD9 mRNA
Genes: CHD9; KIAA0308; KISH2; PRIC320; AD-013; x0008
Study 29650764 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 29650764 — Surrogate Endpoint (SUR): Blood pressure
Study 20467269 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10759875 — Surrogate Endpoint (SUR): Blood pressure
Study 30789801 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10837289 — Surrogate Endpoint (SUR): Hematologic response
Study 1671471 — Surrogate Endpoint (SUR): Serum creatinine
Study 6468768 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30253712 — Surrogate Endpoint (SUR): Blood pressure
Study 26620123 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17617807 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 8876936 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8876936 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 1524654 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30745277 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 18625518 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 10429977 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10429977 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10429977 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10429977 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7481190 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 18850387 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14535021 — Safety Biomarker (SAF): Hyaluronic acid
Study 22551036 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 22551036 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 19703824 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17038243 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17038243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12812018 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 3299016 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28624696 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9034258 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30700946 — Safety Biomarker (SAF): 51Cr-EDTA
Study 30376755 — Predictive Biomarker (PRD): INPP5K mRNA
Genes: INPP5K; PPS; SKIP
Study 10559703 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 18001178 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 805050 — Surrogate Endpoint (SUR): Blood pressure
Study 28617807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19713654 — Surrogate Endpoint (SUR): Blood pressure
Study 17908769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17908769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17908769 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17908769 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 17908769 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 21663696 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21663696 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19067057 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19067057 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 3912001 — Surrogate Endpoint (SUR): Blood pressure
Study 22265923 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 22265923 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31654328 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 28026912 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9072981 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29482662 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 26215765 — Surrogate Endpoint (SUR): Blood pressure
Study 16549077 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 16549077 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 1957404 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31393225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27785737 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 27785737 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 27785737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 21742400 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21742400 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21742400 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16772765 — Surrogate Endpoint (SUR): Blood pressure
Study 7769367 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7769367 — Surrogate Endpoint (SUR): Serum sodium
Study 2178657 — Surrogate Endpoint (SUR): Blood pressure
Study 11713439 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6372133 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21368391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19357525 — Safety Biomarker (SAF): L-acetylcarnitine
Study 15159241 — Surrogate Endpoint (SUR): Blood pressure
Study 3098772 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 20843737 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 18946458 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 12673143 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8842828 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 8471375 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8471375 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 30275282 — Surrogate Endpoint (SUR): Blood pressure
Study 27130973 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24351072 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24351072 — Surrogate Endpoint (SUR): Blood pressure
Study 8982555 — Surrogate Endpoint (SUR): Bone mineral density
Study 8982555 — Surrogate Endpoint (SUR): Serum calcium
Study 31539378 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31539378 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12082590 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7595759 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17634167 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17634167 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 17634167 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 17634167 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17634167 — Surrogate Endpoint (SUR): Serum uric acid
Study 26695077 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 8538187 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 38678 — Surrogate Endpoint (SUR): Blood pressure
Study 21857276 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 8076486 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11136688 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28025372 — Surrogate Endpoint (SUR): Serum creatinine
Study 21075373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17554242 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2181858 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 463054 — Surrogate Endpoint (SUR): Blood pressure
Study 31919583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30594190 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 16643492 — Surrogate Endpoint (SUR): Serum creatinine
Study 14657545 — Surrogate Endpoint (SUR): Serum sodium
Study 10816186 — Safety Biomarker (SAF): DRD2
Study 1452381 — Surrogate Endpoint (SUR): Blood pressure
Study 27438995 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20713879 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20713879 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20713879 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 8568294 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16202258 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16202258 — Surrogate Endpoint (SUR): Serum creatinine
Study 29558967 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 23159258 — Surrogate Endpoint (SUR): Blood pressure
Study 22257480 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19152958 — Surrogate Endpoint (SUR): Blood pressure
Study 11879862 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11879862 — Surrogate Endpoint (SUR): Blood pressure
Study 11879862 — Surrogate Endpoint (SUR): Serum creatinine
Study 10439732 — Surrogate Endpoint (SUR): Blood pressure
Study 2240380 — Surrogate Endpoint (SUR): Serum creatinine
Study 323297 — Surrogate Endpoint (SUR): Blood pressure
Study 22178855 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30888478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30888478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30888478 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27591157 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18089329 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18089329 — Surrogate Endpoint (SUR): Serum creatinine
Study 16258087 — Predictive Biomarker (PRD): Hormone receptor
Study 24473436 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 24473436 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 24473436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17397005 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 6777458 — Surrogate Endpoint (SUR): Blood pressure
Study 19065670 — Monitoring Biomarker (MOI): HBV DNA
Study 9854458 — Surrogate Endpoint (SUR): Blood pressure
Study 28682922 — Surrogate Endpoint (SUR): Blood pressure
Study 24298779 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8951977 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8951977 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 6755527 — Surrogate Endpoint (SUR): Blood pressure
Study 27155740 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10503054 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 10503054 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7477143 — Surrogate Endpoint (SUR): Bone mineral density
Study 26683986 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 26683986 — Surrogate Endpoint (SUR): Blood pressure
Study 23404211 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23404211 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23404211 — Predictive Biomarker (PRD): Hormone receptor
Study 20047626 — Surrogate Endpoint (SUR): Blood pressure
Study 15629218 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 1574973 — Surrogate Endpoint (SUR): Blood pressure
Study 31308004 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 29031409 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 18175148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18175148 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18175148 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18175148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16918262 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16918262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 16918262 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30150756 — Predictive Biomarker (PRD): ADGRL4 mRNA
Genes: ADGRL4; ELTD1; ETL; UNQ202/PRO228
Study 24750839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24750839 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24750839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30592948 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26686755 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26686755 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12195192 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12195192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31067546 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 16840383 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12617264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2