TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15730434 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20594468 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15983452 — Surrogate Endpoint (SUR): Blood pressure
Study 7493659 — Surrogate Endpoint (SUR): Blood pressure
Study 25400242 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 10675381 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9308747 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9308747 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8121306 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2518866 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 19174453 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 9127642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9127642 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9127642 — Safety Biomarker (SAF): IL-6 and IL-10
Study 24723432 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 24723432 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 24723432 — Safety Biomarker (SAF): DRD2
Study 15784480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15784480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26558994 — Surrogate Endpoint (SUR): Bone mineral density
Study 23180154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23180154 — Safety Biomarker (SAF): IL-6 and IL-10
Study 23180154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18793232 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 3392230 — Surrogate Endpoint (SUR): Blood pressure
Study 31563660 — Surrogate Endpoint (SUR): Serum creatinine
Study 18359663 — Monitoring Biomarker (MOI): HBV DNA
Study 12823591 — Monitoring Biomarker (MOI): HBV DNA
Study 31782265 — Surrogate Endpoint (SUR): Blood pressure
Study 31782265 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 21919555 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 20968017 — Predictive Biomarker (PRD): GPSM2 mRNA
Genes: GPSM2; LGN
Study 15622315 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 15622315 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15622315 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 15622315 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 26208409 — Surrogate Endpoint (SUR): Blood pressure
Study 26208409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26208409 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23764933 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 20881066 — Predictive Biomarker (PRD): HRH3 mRNA
Genes: HRH3; GPCR97
Study 10745254 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10745254 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8694202 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26787366 — Surrogate Endpoint (SUR): Blood pressure
Study 16043738 — Surrogate Endpoint (SUR): Blood pressure
Study 16043738 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10475411 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7332915 — Surrogate Endpoint (SUR): Blood pressure
Study 15024332 — Surrogate Endpoint (SUR): Serum calcium
Study 6432119 — Surrogate Endpoint (SUR): Blood pressure
Study 22158114 — Surrogate Endpoint (SUR): Blood pressure
Study 26965712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22648463 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7554973 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7554973 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 27717999 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 19237607 — Predictive Biomarker (PRD): NDRG2 mRNA
Genes: NDRG2; KIAA1248; SYLD
Study 10650302 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6423896 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24059992 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 24059992 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 9625105 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 3045295 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 23719546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23719546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31726490 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31726490 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10723515 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14503 — Surrogate Endpoint (SUR): Blood pressure
Study 28454792 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26120790 — Surrogate Endpoint (SUR): Serum testosterone
Study 21752951 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 22852485 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 22852485 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 22852485 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12890841 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study 12890841 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7766296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28641315 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28641315 — Predictive Biomarker (PRD): Hormone receptor
Study 24617000 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 16565866 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16565866 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16565866 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1296454 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 6084924 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 6084924 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24371300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18528400 — Surrogate Endpoint (SUR): Serum testosterone
Study 12792707 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1694647 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 19586656 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11595291 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29385323 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31477545 — Surrogate Endpoint (SUR): Blood pressure
Study 25466805 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 21464720 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10709673 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 10709673 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12651805 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 1910957 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31481560 — Surrogate Endpoint (SUR): Blood pressure
Study 20977850 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10479672 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 6342220 — Surrogate Endpoint (SUR): Serum creatinine
Study 31457091 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25237116 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 20924214 — Monitoring Biomarker (MOI): HBV DNA
Study 10518228 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29655700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29655700 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24297318 — Surrogate Endpoint (SUR): Blood pressure
Study 10341394 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19874051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12390854 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12390854 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7631600 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27858735 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 27858735 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 27858735 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 24629480 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 18710702 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 11784873 — Surrogate Endpoint (SUR): Urinary oxalate
Study 8553147 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29939302 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 29939302 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29939302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29939302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29939302 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23433966 — Predictive Biomarker (PRD): DSE mRNA
Genes: DSE; SART2
Study 23433966 — Surrogate Endpoint (SUR): Blood pressure
Study 8281528 — Surrogate Endpoint (SUR): Blood pressure
Study 8281528 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25092564 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 22610355 — Predictive Biomarker (PRD): NDP mRNA
Genes: NDP; EVR2
Study 7584934 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7584934 — Surrogate Endpoint (SUR): Blood pressure
Study 31089894 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 25700931 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25700931 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 27930564 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27930564 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 27930564 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 27930564 — Surrogate Endpoint (SUR): Blood pressure
Study 23124178 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 19046248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19046248 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10639539 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3898228 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20179144 — Predictive Biomarker (PRD): ARHGAP15 mRNA
Genes: ARHGAP15; BM-024; BM-030; BM-046
Study 20179144 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study 20179144 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 20179144 — Predictive Biomarker (PRD): POLK mRNA
Genes: POLK; DINB1
Study 17270578 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 17270578 — Surrogate Endpoint (SUR): Blood pressure
Study 23625328 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21799398 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11058707 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 4061268 — Surrogate Endpoint (SUR): Serum potassium
Study 2211564 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 26237520 — Surrogate Endpoint (SUR): Bone mineral density
Study 15327411 — Surrogate Endpoint (SUR): Serum creatinine
Study 29698927 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29698927 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 27279544 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27279544 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 11885789 — Surrogate Endpoint (SUR): Blood pressure
Study 10358675 — Surrogate Endpoint (SUR): Blood pressure
Study 18547173 — Safety Biomarker (SAF): Hyaluronic acid
Study 16080579 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16080579 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16080579 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16080579 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10559528 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30916121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30916121 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30392002 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30392002 — Surrogate Endpoint (SUR): Blood pressure
Study 27032700 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25599306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18476417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18476417 — Monitoring Biomarker (MOI): Procalcitonin
Study 18476417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18476417 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 18476417 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10535397 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 25132119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25132119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22219517 — Surrogate Endpoint (SUR): Blood pressure
Study 19794285 — Surrogate Endpoint (SUR): Bone mineral density
Study 30511316 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 15126514 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 15126514 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23873553 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16687907 — Surrogate Endpoint (SUR): Blood pressure
Study 27545119 — Predictive Biomarker (PRD): TNFSF14 mRNA
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study 27545119 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 21569380 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 21569380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21569380 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21569380 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17974096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14507293 — Surrogate Endpoint (SUR): Blood pressure
Study 29138200 — Surrogate Endpoint (SUR): Blood pressure
Study 16845626 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16845626 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study 1872925 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18373843 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 18373843 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9091027 — Surrogate Endpoint (SUR): Blood pressure
Study 23842110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23842110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23842110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9412256 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8241226 — Surrogate Endpoint (SUR): Blood pressure
Study 25981560 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 9366100 — Surrogate Endpoint (SUR): Serum potassium
Study 9366100 — Surrogate Endpoint (SUR): Blood pressure
Study 9366100 — Surrogate Endpoint (SUR): Serum creatinine
Study 15476910 — Surrogate Endpoint (SUR): Blood pressure
Study 8498314 — Surrogate Endpoint (SUR): Blood pressure
Study 26559015 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16126716 — Surrogate Endpoint (SUR): Blood pressure
Study 21926097 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 7866603 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7866603 — Surrogate Endpoint (SUR): Blood pressure
Study 31381364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26129900 — Predictive Biomarker (PRD): SP4 mRNA
Genes: SP4
Study 12975660 — Predictive Biomarker (PRD): Hormone receptor
Study 11079643 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8947886 — Monitoring Biomarker (MOI): HBV DNA
Study 650879 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 650879 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30649918 — Predictive Biomarker (PRD): TSTD1 mRNA
Genes: TSTD1; KAT
Study 23558806 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 23558806 — Surrogate Endpoint (SUR): Blood pressure
Study 19944358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14970962 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 10023644 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10023644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10023644 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10023644 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30973207 — Surrogate Endpoint (SUR): Blood pressure
Study 26508675 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26508675 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19383582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17223540 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 29888582 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27993811 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 18328842 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 17009230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6376484 — Surrogate Endpoint (SUR): Blood pressure
Study 27121115 — Surrogate Endpoint (SUR): Blood pressure
Study 24520782 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 16398599 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12087922 — Surrogate Endpoint (SUR): Blood pressure
Study 10617243 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10617243 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8538903 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8538903 — Surrogate Endpoint (SUR): Blood pressure
Study 31899122 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 27179796 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17146370 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12164804 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 31549356 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29341404 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 24915612 — Monitoring Biomarker (MOI): HBV DNA
Study 9706062 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30294974 — Safety Biomarker (SAF): Reactive oxygen species
Study 18378859 — Surrogate Endpoint (SUR): Blood pressure
Study 10877010 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 8193735 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8193735 — Surrogate Endpoint (SUR): Blood pressure
Study 15717211 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12760988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3404814 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21949643 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12111127 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 26517283 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 26517283 — Surrogate Endpoint (SUR): Neutralizing antibody