TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30700349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25576240 — Surrogate Endpoint (SUR): Blood pressure
Study 23675422 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23675422 — Surrogate Endpoint (SUR): Blood pressure
Study 23675422 — Surrogate Endpoint (SUR): Serum potassium
Study 9322987 — Surrogate Endpoint (SUR): Blood pressure
Study 31729107 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 31729107 — Surrogate Endpoint (SUR): Blood pressure
Study 18179510 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 18179510 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15086645 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 26226244 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 11090557 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1530174 — Surrogate Endpoint (SUR): Blood pressure
Study 3888116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30679141 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 27083443 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27083443 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 27083443 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24870697 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 24870697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24870697 — Predictive Biomarker (PRD): XBP1 mRNA
Genes: XBP1; TREB5; XBP2
Study 24870697 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 24870697 — Predictive Biomarker (PRD): DNAJC3 mRNA
Genes: DNAJC3; P58IPK; PRKRI
Study 24870697 — Predictive Biomarker (PRD): ATF4 mRNA
Genes: ATF4; CREB2; TXREB
Study 24870697 — Predictive Biomarker (PRD): ATF3 mRNA
Genes: ATF3
Study 24870697 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 11192874 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28734660 — Surrogate Endpoint (SUR): Blood pressure
Study 26239766 — Safety Biomarker (SAF): DRD3
Study 26239766 — Surrogate Endpoint (SUR): Blood pressure
Study 23477485 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 16202717 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10599355 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28662676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25037968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23895803 — Surrogate Endpoint (SUR): Blood pressure
Study 17485711 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 17485711 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 11464225 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7995323 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7995323 — Surrogate Endpoint (SUR): Blood pressure
Study 21960694 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 21960694 — Predictive Biomarker (PRD): ADIPOR2 mRNA
Genes: ADIPOR2; PAQR2
Study 28498975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25691671 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25691671 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25691671 — Predictive Biomarker (PRD): Hormone receptor
Study 19661810 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19661810 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8471228 — Surrogate Endpoint (SUR): Blood pressure
Study 3612782 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3612782 — Surrogate Endpoint (SUR): Blood pressure
Study 15365074 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 11371692 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31629306 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27307526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16882128 — Surrogate Endpoint (SUR): Serum creatinine
Study 27334739 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 27334739 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 22712527 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22712527 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22712527 — Safety Biomarker (SAF): Reactive oxygen species
Study 22321218 — Surrogate Endpoint (SUR): Blood pressure
Study 11274092 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 28669169 — Predictive Biomarker (PRD): Hormone receptor
Study 3098417 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30527177 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25082564 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20595307 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 26568249 — Surrogate Endpoint (SUR): Blood pressure
Study 12182236 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11009276 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8776184 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29684771 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23238142 — Predictive Biomarker (PRD): Hormone receptor
Study 15832331 — Surrogate Endpoint (SUR): Blood pressure
Study 12577328 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 23983239 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 16816926 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11515884 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30945493 — Surrogate Endpoint (SUR): Blood pressure
Study 23590271 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 1735480 — Surrogate Endpoint (SUR): Serum testosterone
Study 6099055 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6266642 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 30835827 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 26952289 — Surrogate Endpoint (SUR): Serum creatinine
Study 12394765 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9783492 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9783492 — Surrogate Endpoint (SUR): Blood pressure
Study 22045098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22045098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 22045098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22045098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18783988 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10457792 — Surrogate Endpoint (SUR): Blood pressure
Study 6437954 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 6437954 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 6437954 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 6437954 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 30284065 — Surrogate Endpoint (SUR): Blood pressure
Study 24383930 — Safety Biomarker (SAF): Interleukin 1
Study 12217302 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 12217302 — Predictive Biomarker (PRD): Hormone receptor
Study 24555909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24555909 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 24555909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19910265 — Surrogate Endpoint (SUR): Blood pressure
Study 12720115 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 8857675 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28056410 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28056410 — Safety Biomarker (SAF): BDNF
Study 27298402 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15055896 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11829202 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9625398 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9625398 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3254768 — Surrogate Endpoint (SUR): Blood pressure
Study 3254768 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 3254768 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3254768 — Surrogate Endpoint (SUR): Serum calcium
Study 12490865 — Surrogate Endpoint (SUR): Serum calcium
Study 21775111 — Surrogate Endpoint (SUR): Blood pressure
Study 11942772 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10322842 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10322842 — Surrogate Endpoint (SUR): Serum creatinine
Study 29098469 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 28933745 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28933745 — Safety Biomarker (SAF): BDNF
Study 24244261 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21146636 — Surrogate Endpoint (SUR): Blood pressure
Study 16556245 — Surrogate Endpoint (SUR): Blood pressure
Study 1285270 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 27558507 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 25609549 — Surrogate Endpoint (SUR): Blood pressure
Study 25609549 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25609549 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8795090 — Surrogate Endpoint (SUR): Blood pressure
Study 31744345 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 30992195 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30992195 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24699854 — Predictive Biomarker (PRD): SLC3A2 mRNA
Genes: SLC3A2; MDU1
Study 24699854 — Predictive Biomarker (PRD): SLC38A2 mRNA
Genes: SLC38A2; ATA2; KIAA1382; SAT2; SNAT2
Study 24699854 — Predictive Biomarker (PRD): SLC36A1 mRNA
Genes: SLC36A1; PAT1
Study 24699854 — Predictive Biomarker (PRD): SLC7A1 mRNA
Genes: SLC7A1; ATRC1; ERR; REC1L
Study 16822792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16822792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16822792 — Safety Biomarker (SAF): Interleukin 1
Study 26383996 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21252061 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 19583678 — Predictive Biomarker (PRD): PLA2G7
Genes: PAFAH; LDL-PLA2
Study 15868618 — Surrogate Endpoint (SUR): Serum creatinine
Study 15868618 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2223415 — Surrogate Endpoint (SUR): Blood pressure
Study 31179500 — Surrogate Endpoint (SUR): Blood pressure
Study 23213072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23213072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28759431 — Safety Biomarker (SAF): Hyaluronic acid
Study 31366396 — Safety Biomarker (SAF): Reactive oxygen species
Study 25652757 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 25652757 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15546434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3518552 — Surrogate Endpoint (SUR): Blood pressure
Study 12854148 — Monitoring Biomarker (MOI): HBV DNA
Study 11711509 — Surrogate Endpoint (SUR): Blood pressure
Study 9164679 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 25543971 — Predictive Biomarker (PRD): MYBPC3 mRNA
Genes: MYBPC3
Study 25543971 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 6366804 — Surrogate Endpoint (SUR): Blood pressure
Study 23296812 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 21596326 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 19635898 — Surrogate Endpoint (SUR): Serum creatinine
Study 16943671 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 10170460 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30266270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28470492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20856256 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8440100 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 367794 — Surrogate Endpoint (SUR): Blood pressure
Study 25468397 — Surrogate Endpoint (SUR): Blood pressure
Study 27005290 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 20157180 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 20157180 — Predictive Biomarker (PRD): FCGR3A
Genes: CD16; CD16a; FcgammaRIIIa; FcGRIIIA
Study 8636336 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 20216563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18381791 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29512468 — Surrogate Endpoint (SUR): Blood pressure
Study 29042830 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24492985 — Surrogate Endpoint (SUR): Blood pressure
Study 15734768 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7863824 — Surrogate Endpoint (SUR): Bone mineral density
Study 20619448 — Surrogate Endpoint (SUR): Blood pressure
Study 24516621 — Surrogate Endpoint (SUR): Blood pressure
Study 20217071 — Predictive Biomarker (PRD): ICOSLG mRNA
Genes: ICOSLG; B7H2; B7RP1; ICOSL; KIAA0653
Study 20217071 — Predictive Biomarker (PRD): TCF3 mRNA
Genes: TCF3; BHLHB21; E2A; ITF1
Study 20217071 — Predictive Biomarker (PRD): VCAM1 mRNA
Genes: VCAM1
Study 20217071 — Predictive Biomarker (PRD): CCR1 mRNA
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 20217071 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 16183965 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 2466846 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28329240 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 19567927 — Surrogate Endpoint (SUR): Blood pressure
Study 15019657 — Surrogate Endpoint (SUR): Serum creatinine
Study 30645844 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30645844 — Surrogate Endpoint (SUR): Blood pressure
Study 30645844 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30645844 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15246968 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26739683 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26739683 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 17394642 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 17394642 — Safety Biomarker (SAF): Hyaluronic acid
Study 7956714 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 7956714 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25287712 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 16340944 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 16340944 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 16340944 — Surrogate Endpoint (SUR): Blood pressure
Study 15037537 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 11130772 — Surrogate Endpoint (SUR): Blood pressure
Study 11130772 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8286176 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 29330312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26916697 — Surrogate Endpoint (SUR): Blood pressure
Study 26916697 — Surrogate Endpoint (SUR): Serum potassium
Study 12860576 — Surrogate Endpoint (SUR): Blood pressure
Study 10583711 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 31755526 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18853090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15126520 — Surrogate Endpoint (SUR): Bone mineral density
Study 15126520 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9543436 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28578208 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28578208 — Safety Biomarker (SAF): BDNF
Study 8797143 — Surrogate Endpoint (SUR): Blood pressure
Study 1480537 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29696916 — Surrogate Endpoint (SUR): Blood pressure
Study 29696916 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29696916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27170340 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31669496 — Surrogate Endpoint (SUR): Bone mineral density
Study 19080093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20110750 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20110750 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11452703 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 24372522 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24372522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24372522 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24372522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12134181 — Surrogate Endpoint (SUR): Blood pressure
Study 7753965 — Surrogate Endpoint (SUR): Blood pressure
Study 19767796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14985687 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11583721 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20029334 — Surrogate Endpoint (SUR): Serum potassium
Study 17145061 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 15229337 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 15229337 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 31985099 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 31668885 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 26498227 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 21549465 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 21549465 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19438397 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9669447 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 9669447 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21228822 — Surrogate Endpoint (SUR): Blood pressure
Study 31200814 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28760787 — Predictive Biomarker (PRD): NISCH mRNA
Genes: NISCH; IRAS; KIAA0975
Study 23663881 — Monitoring Biomarker (MOI): HBV DNA
Study 17374672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17374672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9141919 — Surrogate Endpoint (SUR): Blood pressure
Study 8179165 — Surrogate Endpoint (SUR): Blood pressure
Study 25520127 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 3893343 — Surrogate Endpoint (SUR): Blood pressure
Study 8031109 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23250821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18438829 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 7861873 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22139541 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17684211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3308164 — Surrogate Endpoint (SUR): Blood pressure
Study 20804255 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8726671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1928809 — Surrogate Endpoint (SUR): Blood pressure