TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17701188 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17701188 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29846283 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 27378787 — Surrogate Endpoint (SUR): Blood pressure
Study 27378787 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23602289 — Surrogate Endpoint (SUR): Blood pressure
Study 17699491 — Surrogate Endpoint (SUR): Urinary oxalate
Study 18552237 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 18552237 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 18552237 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18552237 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18552237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10731543 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 10731543 — Surrogate Endpoint (SUR): Bone mineral density
Study 8736459 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8736459 — Surrogate Endpoint (SUR): Blood pressure
Study 8736459 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23230755 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 23230755 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 23230755 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 18418336 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 16185033 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 27595181 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 7715908 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25994074 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25994074 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 25994074 — Predictive Biomarker (PRD): GIPR mRNA
Genes: GIPR
Study 25994074 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9294990 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9294990 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26669912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20399985 — Surrogate Endpoint (SUR): Blood pressure
Study 30979939 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30979939 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study 30979939 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27894601 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18467316 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 16321132 — Surrogate Endpoint (SUR): Bone mineral density
Study 22248672 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20010070 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14582440 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10380088 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 2072372 — Surrogate Endpoint (SUR): Blood pressure
Study 30053212 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 30053212 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1590373 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21868372 — Predictive Biomarker (PRD): MECP2 mRNA
Genes: MECP2
Study 15866550 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12208409 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12208409 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12208409 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12208409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12208409 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31976519 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31976519 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31976519 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30642053 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 28445600 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2913765 — Surrogate Endpoint (SUR): Blood pressure
Study 9798805 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 28245280 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 16460562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16460562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16460562 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8497434 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20458045 — Predictive Biomarker (PRD): Hormone receptor
Study 20458045 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15852994 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 1825969 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1825969 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 17664952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9677501 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 8305420 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8305420 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16452593 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11465759 — Surrogate Endpoint (SUR): Blood pressure
Study 22648253 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 25879244 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 25879244 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 24325609 — Surrogate Endpoint (SUR): Blood pressure
Study 24325609 — Surrogate Endpoint (SUR): Serum creatinine
Study 24325609 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9655770 — Surrogate Endpoint (SUR): Blood pressure
Study 2653765 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 388401 — Surrogate Endpoint (SUR): Blood pressure
Study 388401 — Surrogate Endpoint (SUR): Serum uric acid
Study 388401 — Surrogate Endpoint (SUR): Serum potassium
Study 31947040 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 25229268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25229268 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 25229268 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ADAM11 mRNA
Genes: ADAM11; MDC
Study 25229268 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2539929 — Surrogate Endpoint (SUR): Serum creatinine
Study 21953471 — Surrogate Endpoint (SUR): Bone mineral density
Study 21526669 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21526669 — Surrogate Endpoint (SUR): Blood pressure
Study 31740727 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 23021113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22725836 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 22725836 — Predictive Biomarker (PRD): SLC35A2 mRNA
Genes: SLC35A2; UGALT; UGT; UGTL
Study 21631380 — Predictive Biomarker (PRD): BNIP3 mRNA
Genes: BNIP3; NIP3
Study 21631380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9407253 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 7957538 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7957538 — Surrogate Endpoint (SUR): Blood pressure
Study 7957538 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22248223 — Predictive Biomarker (PRD): CST9 mRNA
Genes: CST9; CLM; CTES7A
Study 11956511 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31601466 — Safety Biomarker (SAF): Hyaluronic acid
Study 21672211 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 19419445 — Predictive Biomarker (PRD): RGR mRNA
Genes: RGR
Study 16398727 — Predictive Biomarker (PRD): NAAA mRNA
Genes: NAAA; ASAHL; PLT
Study 15674006 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26098847 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 15104206 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11439290 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23822141 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15883282 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15883282 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 15883282 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 15883282 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 15883282 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 15883282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15883282 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15883282 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19105579 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19105579 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 12791814 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11069197 — Surrogate Endpoint (SUR): Bone mineral density
Study 12402733 — Predictive Biomarker (PRD): SH2D1A mRNA
Genes: SH2D1A; DSHP; SAP
Study 24158248 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24158248 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20395860 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 11699613 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9591497 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25381393 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 20115947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20115947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16011291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11836281 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 11836281 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1974502 — Surrogate Endpoint (SUR): Blood pressure
Study 15450574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15450574 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 15450574 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15450574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8109545 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8109545 — Surrogate Endpoint (SUR): Blood pressure
Study 30839405 — Surrogate Endpoint (SUR): Serum potassium
Study 30839405 — Surrogate Endpoint (SUR): Blood pressure
Study 26817181 — Surrogate Endpoint (SUR): Blood pressure
Study 31065701 — Predictive Biomarker (PRD): NEB mRNA
Genes: NEB
Study 21669426 — Surrogate Endpoint (SUR): Blood pressure
Study 21669426 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12658027 — Surrogate Endpoint (SUR): Blood pressure
Study 12658027 — Surrogate Endpoint (SUR): Serum creatinine
Study 28551590 — Surrogate Endpoint (SUR): Blood pressure
Study 17687273 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17687273 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17687273 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 17687273 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 28734907 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28734907 — Safety Biomarker (SAF): BDNF
Study 25204295 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 21072892 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7442081 — Surrogate Endpoint (SUR): Blood pressure
Study 23713604 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23587162 — Predictive Biomarker (PRD): IGFBP6 mRNA
Genes: IGFBP6; IBP6
Study 23587162 — Predictive Biomarker (PRD): TSPOAP1 mRNA
Genes: TSPOAP1; BZRAP1; KIAA0612; RBP1; RIMBP1
Study 23587162 — Predictive Biomarker (PRD): PRB4 mRNA
Genes: PRB4
Study 23587162 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 23587162 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 23587162 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 23587162 — Predictive Biomarker (PRD): GPRC5A mRNA
Genes: GPRC5A; GPCR5A; RAI3; RAIG1
Study 23587162 — Predictive Biomarker (PRD): CYP26B1 mRNA
Genes: CYP26B1; CYP26A2; P450RAI2
Study 23587162 — Predictive Biomarker (PRD): PDGFC mRNA
Genes: PDGFC; SCDGF; UNQ174/PRO200
Study 19820031 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 19820031 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17078309 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 15020363 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 15020363 — Surrogate Endpoint (SUR): Bone mineral density
Study 10762505 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 20919542 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15811141 — Surrogate Endpoint (SUR): Blood pressure
Study 19501215 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19501215 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23051684 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 2711919 — Safety Biomarker (SAF): 51Cr-EDTA
Study 24744384 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 26035319 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26035319 — Monitoring Biomarker (MOI): HBV DNA
Study 23930028 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23930028 — Surrogate Endpoint (SUR): Blood pressure
Study 8829017 — Surrogate Endpoint (SUR): Blood pressure
Study 31122994 — Surrogate Endpoint (SUR): Blood pressure
Study 22473250 — Surrogate Endpoint (SUR): Blood pressure
Study 22473250 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30609439 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26310513 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 26254056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21422117 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18512789 — Surrogate Endpoint (SUR): Bone mineral density
Study 16598442 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28351093 — Predictive Biomarker (PRD): ANGPTL8 mRNA
Genes: ANGPTL8; C19orf80; RIFL; UNQ599/PRO1185
Study 23791215 — Predictive Biomarker (PRD): BNC1 mRNA
Genes: BNC1; BNC
Study 17076224 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17076224 — Surrogate Endpoint (SUR): Blood pressure
Study 11770190 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2941206 — Surrogate Endpoint (SUR): Blood pressure
Study 9488190 — Surrogate Endpoint (SUR): Blood pressure
Study 25902885 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19700099 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 16720102 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 15261312 — Surrogate Endpoint (SUR): Blood pressure
Study 24861411 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11008905 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 2693915 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2693915 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 2693915 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2693915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2693915 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28078090 — Surrogate Endpoint (SUR): Blood pressure
Study 26466483 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 22117606 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 17717203 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 9704777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9704777 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 1726988 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TBX2 mRNA
Genes: TBX2
Study 1726988 — Surrogate Endpoint (SUR): Blood pressure
Study 28350787 — Predictive Biomarker (PRD): TOX mRNA
Genes: TOX; KIAA0808
Study 28350787 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study 25247433 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16325937 — Predictive Biomarker (PRD): VPS39 mRNA
Genes: VPS39; KIAA0770; TLP; VAM6
Study 11244389 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1466329 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1466329 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1466329 — Surrogate Endpoint (SUR): Serum creatinine
Study 31690051 — Safety Biomarker (SAF): Reactive oxygen species
Study 2868744 — Surrogate Endpoint (SUR): Blood pressure
Study 6204149 — Surrogate Endpoint (SUR): Blood pressure
Study 29924507 — Surrogate Endpoint (SUR): Blood pressure
Study 27371719 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27371719 — Surrogate Endpoint (SUR): Blood pressure
Study 25453520 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 20619139 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15585567 — Surrogate Endpoint (SUR): Blood pressure
Study 10468758 — Surrogate Endpoint (SUR): Serum creatinine
Study 19842242 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 16785477 — Surrogate Endpoint (SUR): Blood pressure
Study 14555255 — Surrogate Endpoint (SUR): Bone mineral density
Study 10983646 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8227900 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8227900 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 15001596 — Surrogate Endpoint (SUR): Bone mineral density
Study 11331169 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3107602 — Surrogate Endpoint (SUR): Serum potassium
Study 3107602 — Surrogate Endpoint (SUR): Serum calcium
Study 25903109 — Surrogate Endpoint (SUR): Blood pressure
Study 23660180 — Surrogate Endpoint (SUR): Serum creatinine
Study 22489903 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22489903 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 22489903 — Surrogate Endpoint (SUR): Blood pressure
Study 20351325 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 17506785 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15474697 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 7920872 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 2899062 — Surrogate Endpoint (SUR): Blood pressure
Study 24044216 — Monitoring Biomarker (MOI): HBV DNA
Study 17951035 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 17951035 — Surrogate Endpoint (SUR): Blood pressure
Study 12860336 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2127537 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 19808342 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17996561 — Surrogate Endpoint (SUR): Serum potassium
Study 17996561 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3325220 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31366262 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20724949 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20724949 — Surrogate Endpoint (SUR): Blood pressure
Study 20724949 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11487753 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21939502 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21939502 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21939502 — Surrogate Endpoint (SUR): Blood pressure
Study 19108791 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19108791 — Surrogate Endpoint (SUR): Blood pressure
Study 31811383 — Surrogate Endpoint (SUR): Blood pressure
Study 14698649 — Predictive Biomarker (PRD): MAP3K8 mRNA
Genes: MAP3K8; COT; ESTF
Study 2059298 — Surrogate Endpoint (SUR): Serum creatinine
Study 24140166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18561728 — Surrogate Endpoint (SUR): Serum creatinine
Study 15564950 — Surrogate Endpoint (SUR): Blood pressure
Study 9486510 — Surrogate Endpoint (SUR): Blood pressure
Study 8397516 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8397516 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29900538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22231540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22231540 — Surrogate Endpoint (SUR): Blood pressure