TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28092795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28092795 — Surrogate Endpoint (SUR): Sperm parameters
Study 26605849 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 23218844 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 14560228 — Predictive Biomarker (PRD): FSBP mRNA
Genes: FSBP
Study 8879890 — Surrogate Endpoint (SUR): Blood pressure
Study 6465669 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 26875905 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 23190521 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23190521 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11923816 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26116614 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9250437 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12869610 — Surrogate Endpoint (SUR): Blood pressure
Study 31387158 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 31387158 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20425851 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29042392 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 29042392 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23427930 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 19797187 — Surrogate Endpoint (SUR): Blood pressure
Study 16825271 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12868253 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 31424665 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 31424665 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31424665 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 31424665 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 31424665 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 28004259 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 26697176 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23452432 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 16537662 — Surrogate Endpoint (SUR): Blood pressure
Study 23919274 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 12113544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12113544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29653652 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 22464802 — Surrogate Endpoint (SUR): Blood pressure
Study 11879528 — Surrogate Endpoint (SUR): Bone mineral density
Study 11879528 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8652236 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24389453 — Surrogate Endpoint (SUR): Blood pressure
Study 22968159 — Safety Biomarker (SAF): Hyaluronic acid
Study 17439382 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17439382 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9987143 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 29030343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15088136 — Surrogate Endpoint (SUR): Serum creatinine
Study 11427834 — Surrogate Endpoint (SUR): Blood pressure
Study 22613524 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22613524 — Surrogate Endpoint (SUR): Blood pressure
Study 8370856 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 29432644 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 10709886 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1828183 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 1828183 — Surrogate Endpoint (SUR): Serum testosterone
Study 6758745 — Surrogate Endpoint (SUR): Blood pressure
Study 25765144 — Surrogate Endpoint (SUR): Blood pressure
Study 26608978 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23142439 — Surrogate Endpoint (SUR): Bone mineral density
Study 17142523 — Surrogate Endpoint (SUR): Blood pressure
Study 17142523 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11049894 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30111216 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30111216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30111216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22491538 — Surrogate Endpoint (SUR): Blood pressure
Study 11086 — Safety Biomarker (SAF): N-acetylneuraminic acid
Study 11086 — Surrogate Endpoint (SUR): Serum creatinine
Study 27203734 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25371035 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 29547234 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16042894 — Monitoring Biomarker (MOI): HBV DNA
Study 1883793 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 21443612 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 17003366 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 16506860 — Surrogate Endpoint (SUR): Blood pressure
Study 10946879 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 6388586 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24474180 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24474180 — Surrogate Endpoint (SUR): Blood pressure
Study 22350323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20308670 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17296641 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30252061 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9843529 — Safety Biomarker (SAF): Heat shock 70 kDa
Study 31028614 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24491880 — Surrogate Endpoint (SUR): Blood pressure
Study 24491880 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24491880 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19905945 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 31014369 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 2600748 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15619966 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 11204294 — Surrogate Endpoint (SUR): Blood pressure
Study 11950706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7628885 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2487802 — Surrogate Endpoint (SUR): Blood pressure
Study 31629805 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 31629805 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 31629805 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 31629805 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 27301456 — Predictive Biomarker (PRD): PLA2G7 mRNA
Genes: PLA2G7; PAFAH
Study 25516316 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 25516316 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study 25516316 — Predictive Biomarker (PRD): TFF1 mRNA
Genes: TFF1; BCEI; PS2
Study 22883034 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 18362932 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18362932 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10923280 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10923280 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8638517 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8638517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31254596 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 26750378 — Surrogate Endpoint (SUR): Blood pressure
Study 20838372 — Surrogate Endpoint (SUR): Blood pressure
Study 17949392 — Predictive Biomarker (PRD): GABRA2 mRNA
Genes: GABRA2
Study 31480637 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31480637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31480637 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31480637 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29568003 — Surrogate Endpoint (SUR): Blood pressure
Study 23192897 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 22842368 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22842368 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22842368 — Surrogate Endpoint (SUR): Blood pressure
Study 20566009 — Surrogate Endpoint (SUR): Bone mineral density
Study 7930718 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31142294 — Surrogate Endpoint (SUR): Blood pressure
Study 21298840 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30860573 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30860573 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study 24408035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17253178 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28079600 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18287807 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18287807 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 8836914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1562097 — Surrogate Endpoint (SUR): Blood pressure
Study 3933677 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24739538 — Surrogate Endpoint (SUR): Blood pressure
Study 29080386 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29080386 — Surrogate Endpoint (SUR): Serum uric acid
Study 27869287 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27869287 — Surrogate Endpoint (SUR): Blood pressure
Study 27434393 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 27434393 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17689627 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9650737 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8077800 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31934946 — Predictive Biomarker (PRD): BTG2 mRNA
Genes: BTG2; PC3
Study 31934946 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17092978 — Surrogate Endpoint (SUR): Blood pressure
Study 15158296 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 10439887 — Surrogate Endpoint (SUR): Blood pressure
Study 23393104 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23393104 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17824470 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17824470 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24150249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11441903 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19303015 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15243278 — Surrogate Endpoint (SUR): Bone mineral density
Study 11061584 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 11061584 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22605788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22605788 — Surrogate Endpoint (SUR): Blood pressure
Study 22605788 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19758440 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19758440 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19758440 — Predictive Biomarker (PRD): Hormone receptor
Study 19758440 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24530156 — Surrogate Endpoint (SUR): Bone mineral density
Study 31574794 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31574794 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24995515 — Monitoring Biomarker (MOI): HBV DNA
Study 21078951 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28329919 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 26244978 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 24257178 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1447105 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1447105 — Surrogate Endpoint (SUR): Blood pressure
Study 25688059 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25688059 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29508689 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 1828348 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1828348 — Surrogate Endpoint (SUR): Blood pressure
Study 29470317 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29470317 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29470317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19478215 — Surrogate Endpoint (SUR): Blood pressure
Study 10624641 — Surrogate Endpoint (SUR): Blood pressure
Study 8745137 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 31216321 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22169051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18175518 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 12410054 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12410054 — Surrogate Endpoint (SUR): Blood pressure
Study 10218748 — Surrogate Endpoint (SUR): Blood pressure
Study 29733225 — Surrogate Endpoint (SUR): Blood pressure
Study 31999297 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22539379 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22539379 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8739811 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 1831059 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6642790 — Surrogate Endpoint (SUR): Blood pressure
Study 26702120 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22574737 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 22574737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11444420 — Surrogate Endpoint (SUR): Serum calcium
Study 28697767 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28697767 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28697767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19762739 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19762739 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19762739 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 19762739 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19762739 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 19762739 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 19762739 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17174222 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15185314 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9664985 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26083005 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15362963 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19349544 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16775558 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21037100 — Safety Biomarker (SAF): C-C motif chemokine 19
Genes: CCL19; ELC; MIP3B; SCYA19
Study 21037100 — Predictive Biomarker (PRD): CCL21 mRNA
Genes: CCL21; SCYA21; UNQ784/PRO1600
Study 21037100 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9381994 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30509713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30509713 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20349155 — Surrogate Endpoint (SUR): Blood pressure
Study 31067674 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31067674 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10792330 — Surrogate Endpoint (SUR): Bone mineral density
Study 2780087 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22578254 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1888800 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 22113064 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22113064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22113064 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22113064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12794818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10520056 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19892499 — Surrogate Endpoint (SUR): Bone mineral density
Study 10051289 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7670117 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 1688039 — Surrogate Endpoint (SUR): Blood pressure
Study 21991949 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31296256 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 31296256 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21146229 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 10890611 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21573819 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 17307426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9356783 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31762471 — Surrogate Endpoint (SUR): Blood pressure
Study 30790211 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9713652 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 9713652 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24884563 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 22648843 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19956970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19956970 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7566945 — Surrogate Endpoint (SUR): Bone mineral density
Study 26144908 — Surrogate Endpoint (SUR): Bone mineral density
Study 8670314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28434475 — Surrogate Endpoint (SUR): Blood pressure
Study 23296186 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 21788428 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21788428 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7706601 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31885755 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31885755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31885755 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26951335 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study 18212498 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 18212498 — Surrogate Endpoint (SUR): Serum creatinine
Study 10735703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10735703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10735703 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9187454 — Surrogate Endpoint (SUR): Bacterial count
Study 21066885 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 21066885 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17885694 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD