TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11276371 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11276371 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 11276371 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30566760 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29092078 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 25307674 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 25307674 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 25307674 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23811682 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23811682 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 23811682 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20740300 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 20740300 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20740300 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12011966 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31957601 — Surrogate Endpoint (SUR): Blood pressure
Study 22610178 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 22610178 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18460957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18460957 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3325395 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29720161 — Surrogate Endpoint (SUR): Blood pressure
Study 18762707 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18762707 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14658975 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27803925 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 27803925 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 27803925 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Amyloid beta A4 protein
Genes: APP; A4; AD1
Study 24815948 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 24815948 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 2160665 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2160665 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 26306902 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18612053 — Surrogate Endpoint (SUR): Blood pressure
Study 18612053 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11918762 — Surrogate Endpoint (SUR): Serum creatinine
Study 21975558 — Surrogate Endpoint (SUR): Bone mineral density
Study 16118802 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12358871 — Surrogate Endpoint (SUR): Blood pressure
Study 31404106 — Predictive Biomarker (PRD): PARK7 mRNA
Genes: PARK7
Study 31404106 — Predictive Biomarker (PRD): TARDBP mRNA
Genes: TARDBP; TDP43
Study 31404106 — Predictive Biomarker (PRD): TLN1 mRNA
Genes: TLN1; KIAA1027; TLN
Study 31404106 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 28306591 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21701421 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 27866517 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 23327958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23327958 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9196161 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1542854 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 1542854 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9556142 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30595477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29229110 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 25367164 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 20945064 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 22291076 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 9856918 — Surrogate Endpoint (SUR): Blood pressure
Study 2214868 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31325257 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25552367 — Predictive Biomarker (PRD): MCAM mRNA
Genes: MCAM; MUC18
Study 30224319 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18922117 — Predictive Biomarker (PRD): Hormone receptor
Study 18922117 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15797962 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 8594954 — Surrogate Endpoint (SUR): Blood pressure
Study 26299229 — Surrogate Endpoint (SUR): Blood pressure
Study 3234516 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8614419 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3027267 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24579221 — Safety Biomarker (SAF): Hyaluronic acid
Study 7616988 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24987193 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 24987193 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 1941407 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 30535871 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30535871 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30535871 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30535871 — Surrogate Endpoint (SUR): Blood pressure
Study 29030697 — Surrogate Endpoint (SUR): Blood pressure
Study 20381870 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 20381870 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 20381870 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 20381870 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 20381870 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 20381870 — Predictive Biomarker (PRD): HTRA1 mRNA
Genes: HTRA1; HTRA; PRSS11
Study 15798915 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12461401 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 12461401 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 10757273 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10757273 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29960810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25137874 — Surrogate Endpoint (SUR): Blood pressure
Study 20146169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17909315 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16184581 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26859236 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26859236 — Safety Biomarker (SAF): BDNF
Study 11817991 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8785399 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29121350 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 24565591 — Surrogate Endpoint (SUR): Blood pressure
Study 15247107 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28011757 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17561009 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11795345 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9732298 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 3054641 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 28319586 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28319586 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 28319586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28319586 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 28319586 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 28319586 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 14993506 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 2944924 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24674975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17278979 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17278979 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 639430 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30985725 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 30985725 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29911792 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26228672 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11405833 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 9210608 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7957341 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 11340365 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9175051 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 9175051 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30613057 — Surrogate Endpoint (SUR): Blood pressure
Study 27005766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31706345 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 22541418 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10729387 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 28627930 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28627930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14742367 — Surrogate Endpoint (SUR): Blood pressure
Study 10967152 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22590530 — Predictive Biomarker (PRD): C6orf15 mRNA
Genes: C6orf15; STG; UNQ1840/PRO3566
Study 18957124 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10648315 — Surrogate Endpoint (SUR): Blood pressure
Study 31831364 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 30600702 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30600702 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30600702 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28587609 — Surrogate Endpoint (SUR): Blood pressure
Study 25891091 — Predictive Biomarker (PRD): TRIM32 mRNA
Genes: TRIM32; HT2A
Study 21875859 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17593025 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 12468610 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 12468610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7639163 — Surrogate Endpoint (SUR): Blood pressure
Study 26100336 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 26100336 — Predictive Biomarker (PRD): AQP9 mRNA
Genes: AQP9; SSC1
Study 21729566 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21729566 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19383225 — Safety Biomarker (SAF): Reactive oxygen species
Study 19383225 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9376990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9376990 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 9376990 — Safety Biomarker (SAF): Interleukin 1
Study 9376990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25886707 — Safety Biomarker (SAF): Reactive oxygen species
Study 20521033 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 20521033 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31654573 — Monitoring Biomarker (MOI): HBV DNA
Study 25380901 — Surrogate Endpoint (SUR): Serum creatinine
Study 19594741 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 11947915 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10487682 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1872266 — Surrogate Endpoint (SUR): Blood pressure
Study 29338073 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 29338073 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29338073 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 25979762 — Safety Biomarker (SAF): miR-34c
Genes: MIR34C
Study 22595020 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 22595020 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 22595020 — Safety Biomarker (SAF): Reactive oxygen species
Study 1920698 — Surrogate Endpoint (SUR): Blood pressure
Study 31840813 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 31840813 — Surrogate Endpoint (SUR): Blood pressure
Study 22835219 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22835219 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10836730 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10836730 — Surrogate Endpoint (SUR): Blood pressure
Study 16822279 — Surrogate Endpoint (SUR): Blood pressure
Study 19151303 — Surrogate Endpoint (SUR): Blood pressure
Study 16864812 — Surrogate Endpoint (SUR): Serum creatinine
Study 8456759 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20521985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20521985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10764316 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 10764316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9034259 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8287667 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30178092 — Surrogate Endpoint (SUR): Serum creatinine
Study 30178092 — Surrogate Endpoint (SUR): Serum sodium
Study 30178092 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28143522 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 28143522 — Predictive Biomarker (PRD): HPGD mRNA
Genes: HPGD; PGDH1; SDR36C1
Study 28143522 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 14761117 — Predictive Biomarker (PRD): FCGR2B
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study 14761117 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 20178064 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 20178064 — Surrogate Endpoint (SUR): Blood pressure
Study 20178064 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8469914 — Surrogate Endpoint (SUR): Blood pressure
Study 26954313 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 12792504 — Surrogate Endpoint (SUR): Serum creatinine
Study 12792504 — Surrogate Endpoint (SUR): Blood pressure
Study 12792504 — Surrogate Endpoint (SUR): Serum uric acid
Study 1364978 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31446803 — Surrogate Endpoint (SUR): Blood pressure
Study 1575821 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 1575821 — Surrogate Endpoint (SUR): Serum triglycerides
Study 1575821 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30040791 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22355401 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22355401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22355401 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 22355401 — Surrogate Endpoint (SUR): Blood pressure
Study 9620900 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31665578 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 29186198 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 11699169 — Surrogate Endpoint (SUR): Blood pressure
Study 30157946 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20354760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18552688 — Surrogate Endpoint (SUR): Blood pressure
Study 15780531 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17261503 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 9666879 — Surrogate Endpoint (SUR): Bone mineral density
Study 3140622 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 18638603 — Predictive Biomarker (PRD): Liver iron
Study 8776678 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3881209 — Surrogate Endpoint (SUR): Blood pressure
Study 31101977 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 31101977 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31101977 — Surrogate Endpoint (SUR): Serum testosterone
Study 27082551 — Surrogate Endpoint (SUR): Blood pressure
Study 22286528 — Surrogate Endpoint (SUR): Blood pressure
Study 9673558 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 25487027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25487027 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24070809 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24070809 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 24070809 — Predictive Biomarker (PRD): FZD4 mRNA
Genes: FZD4
Study 24070809 — Predictive Biomarker (PRD): HTRA1 mRNA
Genes: HTRA1; HTRA; PRSS11
Study 24070809 — Predictive Biomarker (PRD): EPAS1 mRNA
Genes: EPAS1; BHLHE73; HIF2A; MOP2; PASD2
Study 24070809 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18728936 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 30250134 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30250134 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17712585 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 319922 — Surrogate Endpoint (SUR): Blood pressure
Study 27483410 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 27483410 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 27483410 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17112853 — Surrogate Endpoint (SUR): Blood pressure
Study 14988972 — Surrogate Endpoint (SUR): Blood pressure
Study 28561039 — Predictive Biomarker (PRD): LIPA mRNA
Genes: LIPA
Study 11093050 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11093050 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 29314659 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 29314659 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26854246 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22880097 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20956902 — Surrogate Endpoint (SUR): Blood pressure
Study 10828084 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 10828084 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10828084 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 10828084 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6345370 — Surrogate Endpoint (SUR): Blood pressure
Study 25493193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25493193 — Surrogate Endpoint (SUR): Blood pressure
Study 25493193 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25493193 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22516310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29126292 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6378988 — Surrogate Endpoint (SUR): Blood pressure
Study 26681752 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 26681752 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24375159 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24375159 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15068495 — Surrogate Endpoint (SUR): Bone mineral density
Study 31923768 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23577699 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20078390 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34