TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00300469 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00300469 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03136185 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT04485078 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT01697800 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01247220 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01247220 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04013490 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04013490 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02310971 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT01030016 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03402373 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02274649 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study NCT01688622 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study NCT02610218 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02610218 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT01627067 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT01627067 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00682799 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT00682799 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03532893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00019006 — Pharmacodynamic Biomarker (PDY): RAS peptides
Study NCT03449537 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT01728805 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study NCT01644474 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01644474 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03320460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03837821 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT01822548 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03387514 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03607903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03799679 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00904150 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study NCT00904150 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00904150 — Predictive Biomarker (PRD): SYNE1 mRNA
Genes: SYNE1; C6orf98; KIAA0796; KIAA1262; KIAA1756; MYNE1
Study NCT04466085 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01751321 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00876512 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT05744076 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00904826 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT03820167 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT00975221 — Surrogate Endpoint (SUR): Serum calcium
Study NCT05833919 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03613714 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03319030 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02037828 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT03145805 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study NCT03000140 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03002545 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00783471 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02951910 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02171429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01657669 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03443375 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02037802 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00303238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01949194 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03365375 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00289237 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00505726 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03055247 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04023409 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT00005200 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01677780 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT00975572 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study NCT00005763 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01957423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04367402 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT00005207 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT05515926 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02256189 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02720510 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02766153 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02013973 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02487537 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01013376 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02316691 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02316691 — Predictive Biomarker (PRD): CXCR5 mRNA
Genes: CXCR5; BLR1; MDR15
Study NCT04127084 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04127084 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04215185 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01565200 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03668665 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02684578 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03663777 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00956280 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03363867 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03363867 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01554943 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study NCT01201070 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT01968096 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT04386564 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04386564 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01291329 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03071224 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00818883 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02005536 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01438112 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04478539 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00659607 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02066350 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03943056 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01468922 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT03443765 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT01989546 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01989546 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT01989546 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT01989546 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT01989546 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study NCT01989546 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study NCT01777594 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03292146 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04279080 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study NCT00735943 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03297229 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00088751 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00088751 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT03462446 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT02683915 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT02683915 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT04836143 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01588145 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00807846 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02343588 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02343588 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02343588 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02861677 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02861677 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04270305 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT03877705 — Surrogate Endpoint (SUR): Bacterial count
Study NCT01894711 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01894711 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00303108 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01734850 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01734850 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02512666 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05437224 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00632463 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04263090 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03010995 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03010995 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02834611 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study NCT01029262 — Predictive Biomarker (PRD): Chromosome 5q
Study NCT03299400 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00284089 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03728439 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04238442 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02233699 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT00370006 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00620048 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03892369 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT01778491 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01592279 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03295734 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00760266 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04397731 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study NCT02973360 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03910348 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00556374 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00005948 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00005948 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00749801 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02422927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01335295 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00921661 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01221805 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00745641 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03050437 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03050437 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02980978 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04448236 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study NCT01272908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01222000 — Predictive Biomarker (PRD): TGM1 mRNA
Genes: TGM1; KTG
Study NCT01222000 — Predictive Biomarker (PRD): ABCA12 mRNA
Genes: ABCA12; ABC12
Study NCT01222000 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study NCT03577093 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT03577093 — Predictive Biomarker (PRD): UBE2L6 mRNA
Genes: UBE2L6; UBCH8
Study NCT03577093 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT03577093 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03577093 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study NCT03577093 — Pharmacodynamic Biomarker (PDY): Cyclin-dependent kinase 1
Genes: CDK1; CDC2; CDC28A; CDKN1; P34CDC2
Study NCT03577093 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study NCT03577093 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT04396223 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02131064 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02690012 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04118478 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02183870 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT00535808 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02460926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01081873 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01904968 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01904968 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01565096 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01724502 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study NCT03901469 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03901469 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03901469 — Predictive Biomarker (PRD): TACSTD2 mRNA
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT03273738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01452958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04352322 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02282319 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02166216 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT03257085 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03663803 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03212404 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00252213 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02083510 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02083510 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02328690 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02011204 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT01776684 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01776684 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT00678990 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT01425632 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02963688 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01717105 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01717105 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00298064 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00948519 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04398784 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04398784 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02843958 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT04250051 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT02701751 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02268500 — Surrogate Endpoint (SUR): Serum antibody concentration
Study NCT04164771 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03839394 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03839394 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01830192 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT00910364 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT02462304 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02462304 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01119274 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01119274 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT00710229 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00710229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04438005 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT02267070 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02267070 — Safety Biomarker (SAF): BDNF
Study NCT01651936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01651936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02769208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02769208 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02769208 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02199392 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03904537 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04913909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01700673 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00827151 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01534455 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01384838 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02927509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03795363 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03559439 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01856309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01799720 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study NCT00002720 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02394899 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01502540 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01900041 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT01578837 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03164772 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02920996 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02920996 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA