TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9010696 — Surrogate Endpoint (SUR): Blood pressure
Study 10482998 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 31551213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12113669 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 2829262 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15216449 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 15216449 — Surrogate Endpoint (SUR): Blood pressure
Study 9754991 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 137921 — Surrogate Endpoint (SUR): Blood pressure
Study 28876367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28876367 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25877855 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25877855 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23841259 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23841259 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19958861 — Surrogate Endpoint (SUR): Blood pressure
Study 15490272 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26604649 — Monitoring Biomarker (MOI): HBV DNA
Study 21199833 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21199833 — Surrogate Endpoint (SUR): Serum sodium
Study 12374713 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30700347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30700347 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18553045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3718170 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 27773665 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21903737 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18367240 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 6349160 — Surrogate Endpoint (SUR): Blood pressure
Study 31489420 — Surrogate Endpoint (SUR): Blood pressure
Study 30856079 — Predictive Biomarker (PRD): SFRP5 mRNA
Genes: SFRP5; FRP1B; SARP3
Study 30856079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29210957 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 26124486 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 19114204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10971307 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8855175 — Monitoring Biomarker (MOI): HBV DNA
Study 28237867 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 28237867 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28237867 — Predictive Biomarker (PRD): HRAS mRNA
Genes: HRAS; HRAS1
Study 28237867 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28237867 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26233808 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 15329068 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 20442758 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12034036 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16467232 — Predictive Biomarker (PRD): Hormone receptor
Study 3528889 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25364946 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25364946 — Safety Biomarker (SAF): BDNF
Study 20645484 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16027336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16027336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3026690 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16401239 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 16401239 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10386189 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 10386189 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 19709328 — Surrogate Endpoint (SUR): Serum creatinine
Study 14732826 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9842820 — Surrogate Endpoint (SUR): Blood pressure
Study 8128188 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29188883 — Surrogate Endpoint (SUR): Blood pressure
Study 25985245 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 24034093 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24034093 — Surrogate Endpoint (SUR): Serum creatinine
Study 3518773 — Surrogate Endpoint (SUR): Blood pressure
Study 29469206 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27591767 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 15930221 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15930221 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31219771 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 31219771 — Surrogate Endpoint (SUR): Blood pressure
Study 23547209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23547209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21470404 — Surrogate Endpoint (SUR): Serum potassium
Study 21470404 — Surrogate Endpoint (SUR): Blood pressure
Study 28402745 — Surrogate Endpoint (SUR): Blood pressure
Study 23868508 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 21606533 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 16970162 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 16970162 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 11061497 — Surrogate Endpoint (SUR): Bone mineral density
Study 9051387 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9310283 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 25774646 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 25850425 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 21120518 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 19248105 — Safety Biomarker (SAF): Hyaluronic acid
Study 11723147 — Surrogate Endpoint (SUR): Blood pressure
Study 9340918 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8033658 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8033658 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25987072 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25987072 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 19384840 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19384840 — Surrogate Endpoint (SUR): Blood pressure
Study 14623807 — Surrogate Endpoint (SUR): Blood pressure
Study 29807228 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 29605103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29798036 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24947722 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17988728 — Surrogate Endpoint (SUR): Blood pressure
Study 15628051 — Surrogate Endpoint (SUR): Blood pressure
Study 9313601 — Surrogate Endpoint (SUR): Blood pressure
Study 19506392 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14607207 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31693879 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 29202563 — Safety Biomarker (SAF): Hyaluronic acid
Study 9833595 — Surrogate Endpoint (SUR): Blood pressure
Study 30953792 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31944221 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 23837833 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 31234806 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 31234806 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 15198873 — Surrogate Endpoint (SUR): Blood pressure
Study 8988940 — Surrogate Endpoint (SUR): Blood pressure
Study 2904474 — Surrogate Endpoint (SUR): Blood pressure
Study 10761807 — Surrogate Endpoint (SUR): Blood pressure
Study 28822166 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28822166 — Surrogate Endpoint (SUR): Blood pressure
Study 28822166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23582671 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 7827218 — Surrogate Endpoint (SUR): Blood pressure
Study 3415803 — Safety Biomarker (SAF): 51Cr-EDTA
Study 3415803 — Surrogate Endpoint (SUR): Blood pressure
Study 12925049 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12925049 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12925049 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 20153487 — Surrogate Endpoint (SUR): Blood pressure
Study 14673126 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 31147254 — Surrogate Endpoint (SUR): Blood pressure
Study 28646804 — Surrogate Endpoint (SUR): Blood pressure
Study 27339107 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 25456116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25456116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1927301 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20555371 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 20555371 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19228402 — Surrogate Endpoint (SUR): Blood pressure
Study 11553000 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11553000 — Safety Biomarker (SAF): Human leucocyte antigen
Study 23999933 — Surrogate Endpoint (SUR): Blood pressure
Study 18490229 — Surrogate Endpoint (SUR): Blood pressure
Study 18490229 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8136096 — Surrogate Endpoint (SUR): Blood pressure
Study 29328639 — Safety Biomarker (SAF): Hyaluronic acid
Study 22948448 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 21115926 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 16805934 — Surrogate Endpoint (SUR): Blood pressure
Study 18505746 — Surrogate Endpoint (SUR): Blood pressure
Study 24305063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24305063 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31728894 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15586301 — Surrogate Endpoint (SUR): Blood pressure
Study 11141143 — Surrogate Endpoint (SUR): Blood pressure
Study 8989179 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23686894 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23686894 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18667923 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16313110 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 16313110 — Safety Biomarker (SAF): Urinary microalbumin
Study 11875324 — Surrogate Endpoint (SUR): Blood pressure
Study 11426528 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 11426528 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2552802 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 2552802 — Surrogate Endpoint (SUR): Serum creatinine
Study 2552802 — Surrogate Endpoint (SUR): Serum uric acid
Study 29058175 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29058175 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29058175 — Predictive Biomarker (PRD): Hormone receptor
Study 29079475 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 27418817 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 22246943 — Surrogate Endpoint (SUR): Blood pressure
Study 20465146 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 15732035 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 1657528 — Surrogate Endpoint (SUR): Blood pressure
Study 27483130 — Surrogate Endpoint (SUR): Blood pressure
Study 15848906 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8738665 — Surrogate Endpoint (SUR): Serum creatinine
Study 8738665 — Surrogate Endpoint (SUR): Blood pressure
Study 2883677 — Surrogate Endpoint (SUR): Blood pressure
Study 27098404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16168734 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12706640 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 12706640 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 24960665 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 21036891 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 21036891 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 2653621 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2653621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31630035 — Predictive Biomarker (PRD): CBX1 mRNA
Genes: CBX1; CBX
Study 26391131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24259978 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 20195183 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 7884951 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20638322 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 12100060 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12100060 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10791216 — Surrogate Endpoint (SUR): Serum creatinine
Study 29168044 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21054769 — Surrogate Endpoint (SUR): Blood pressure
Study 8529777 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22753310 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 22753310 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 16954134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26451761 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9828907 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9828907 — Surrogate Endpoint (SUR): Serum testosterone
Study 24246119 — Surrogate Endpoint (SUR): Serum sodium
Study 19029469 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19029469 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19029469 — Surrogate Endpoint (SUR): Blood pressure
Study 19029469 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26579947 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 21317148 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3025927 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27098820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27098820 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27098820 — Surrogate Endpoint (SUR): Blood pressure
Study 24490888 — Surrogate Endpoint (SUR): Blood pressure
Study 22569236 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 18823658 — Surrogate Endpoint (SUR): Blood pressure
Study 25544738 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 25544738 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 17879532 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15536655 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 2757878 — Surrogate Endpoint (SUR): Blood pressure
Study 18678578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10336577 — Surrogate Endpoint (SUR): Blood pressure
Study 29587831 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 29587831 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 22940462 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 6982626 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28963290 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 22886490 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 22886490 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 22886490 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 22886490 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17446997 — Surrogate Endpoint (SUR): Blood pressure
Study 8737755 — Surrogate Endpoint (SUR): Blood pressure
Study 6741192 — Surrogate Endpoint (SUR): Blood pressure
Study 19920081 — Surrogate Endpoint (SUR): Blood pressure
Study 11302475 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31370223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25970229 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10685239 — Surrogate Endpoint (SUR): Serum sodium
Study 8596489 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3155939 — Surrogate Endpoint (SUR): Blood pressure
Study 17922939 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17922939 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30634204 — Surrogate Endpoint (SUR): Serum calcium
Study 21841087 — Predictive Biomarker (PRD): TNC mRNA
Genes: TNC; HXB
Study 21841087 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 24875671 — Surrogate Endpoint (SUR): Blood pressure
Study 24875671 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 24875671 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21978663 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 27789120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23548455 — Surrogate Endpoint (SUR): Bone mineral density
Study 15152874 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23774331 — Surrogate Endpoint (SUR): Blood pressure
Study 15253739 — Safety Biomarker (SAF): Reactive oxygen species
Study 2881320 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30407354 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28608398 — Predictive Biomarker (PRD): RUNX2 mRNA
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 28608398 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28608398 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22431415 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 21909502 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17519147 — Surrogate Endpoint (SUR): Blood pressure
Study 803203 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 28502503 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28502503 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26134988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26134988 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23375799 — Surrogate Endpoint (SUR): Bone mineral density
Study 1728930 — Surrogate Endpoint (SUR): Blood pressure
Study 22208555 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22208555 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 22208555 — Safety Biomarker (SAF): BDNF
Study 20466742 — Surrogate Endpoint (SUR): Total kidney volume
Study 10963288 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 12859157 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26489028 — Surrogate Endpoint (SUR): Serum creatinine
Study 24338058 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 658870 — Surrogate Endpoint (SUR): Blood pressure
Study 31096728 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 15786695 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 17244442 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10371654 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1894888 — Surrogate Endpoint (SUR): Blood pressure
Study 31502856 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 10443671 — Surrogate Endpoint (SUR): Serum calcium
Study 7847975 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7658777 — Surrogate Endpoint (SUR): Blood pressure
Study 79709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12