TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16449816 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 2881788 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 2881788 — Surrogate Endpoint (SUR): Blood pressure
Study 2881788 — Safety Biomarker (SAF): 51Cr-EDTA
Study 11063406 — Surrogate Endpoint (SUR): Blood pressure
Study 6401753 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 6401753 — Surrogate Endpoint (SUR): Blood pressure
Study 30184105 — Predictive Biomarker (PRD): GSK3B mRNA
Genes: GSK3B
Study 30184105 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 30184105 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29955768 — Predictive Biomarker (PRD): CYLD mRNA
Genes: CYLD; CYLD1; KIAA0849; HSPC057
Study 29955768 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 24279707 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 10021957 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10021957 — Surrogate Endpoint (SUR): Blood pressure
Study 18000176 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 18000176 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28260702 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11208941 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9892029 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 7985254 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23458405 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 21819545 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21819545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21819545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21819545 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7979805 — Surrogate Endpoint (SUR): Serum testosterone
Study 31098639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 23507997 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9052314 — Surrogate Endpoint (SUR): Blood pressure
Study 29771450 — Surrogate Endpoint (SUR): Blood pressure
Study 16307968 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22406101 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 16101723 — Surrogate Endpoint (SUR): Bone mineral density
Study 9683312 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9683312 — Surrogate Endpoint (SUR): Blood pressure
Study 21780209 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21780209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19455053 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19455053 — Surrogate Endpoint (SUR): Blood pressure
Study 19455053 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15272911 — Safety Biomarker (SAF): CYP11B1 mRNA
Genes: CYP11B1; S11BH
Study 29195133 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 27051055 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 20135748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20135748 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3966831 — Predictive Biomarker (PRD): MOXD1 mRNA
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 27783849 — Predictive Biomarker (PRD): KIF20A mRNA
Genes: KIF20A; MKLP2; RAB6KIFL
Study 27783849 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 27783849 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 27783849 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 23540891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19239406 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27050139 — Predictive Biomarker (PRD): FGF18 mRNA
Genes: FGF18; UNQ420/PRO856
Study 22508830 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20181970 — Surrogate Endpoint (SUR): Bone mineral density
Study 20181970 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18042015 — Surrogate Endpoint (SUR): Serum creatinine
Study 11115824 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9043839 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9043839 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15117604 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 28199364 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 28199364 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25720712 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24088416 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17516307 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 17516307 — Surrogate Endpoint (SUR): Blood pressure
Study 23611977 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16952492 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 16952492 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 16952492 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 16952492 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16952492 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15609591 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 29512200 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 12375804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12375804 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7573998 — Surrogate Endpoint (SUR): Blood pressure
Study 27399131 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23082133 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23082133 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23082133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23082133 — Surrogate Endpoint (SUR): Blood pressure
Study 11854983 — Surrogate Endpoint (SUR): Blood pressure
Study 2884861 — Surrogate Endpoint (SUR): Blood pressure
Study 2884861 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15716697 — Surrogate Endpoint (SUR): Blood pressure
Study 21747089 — Predictive Biomarker (PRD): Microsatellite instability
Study 19164269 — Surrogate Endpoint (SUR): Blood pressure
Study 19164269 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2492674 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26010632 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15166883 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 9630024 — Surrogate Endpoint (SUR): Blood pressure
Study 25123562 — Surrogate Endpoint (SUR): Bone mineral density
Study 21914136 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1439640 — Surrogate Endpoint (SUR): Blood pressure
Study 31615996 — Predictive Biomarker (PRD): MMP7 mRNA
Genes: MMP7; MPSL1; PUMP1
Study 22582911 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 17155971 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11856461 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 11856461 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28071 — Surrogate Endpoint (SUR): Blood pressure
Study 7729044 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 21860000 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 17925885 — Predictive Biomarker (PRD): PIGA mRNA
Genes: PIGA
Study 17925885 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 15514875 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31079555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31079555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31079555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19555037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17004893 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30144099 — Surrogate Endpoint (SUR): Blood pressure
Study 18159148 — Monitoring Biomarker (MOI): HBV DNA
Study 18486419 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 12775312 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20209619 — Predictive Biomarker (PRD): Hormone receptor
Study 10748449 — Predictive Biomarker (PRD): PRLR mRNA
Genes: PRLR
Study 29342453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29342453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29342453 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 29342453 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 29342453 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29342453 — Safety Biomarker (SAF): Interleukin 1
Study 29342453 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 29342453 — Predictive Biomarker (PRD): miR-21-5p
Genes: MIR21
Study 29342453 — Predictive Biomarker (PRD): miR-187
Genes: MIR187
Study 29342453 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 16186434 — Surrogate Endpoint (SUR): Blood pressure
Study 28074798 — Surrogate Endpoint (SUR): Blood pressure
Study 12784100 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 24456362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25095746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25095746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25095746 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 25095746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25095746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19363969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 19363969 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2462943 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28254959 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23529704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23529704 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21948693 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 21597981 — Surrogate Endpoint (SUR): Blood pressure
Study 11928041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11928041 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11928041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20886228 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 17035446 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10373062 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8901839 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 8901839 — Surrogate Endpoint (SUR): Blood pressure
Study 21478189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21478189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23630950 — Surrogate Endpoint (SUR): Blood pressure
Study 30636547 — Surrogate Endpoint (SUR): Blood pressure
Study 30215466 — Surrogate Endpoint (SUR): Blood pressure
Study 26579834 — Surrogate Endpoint (SUR): Blood pressure
Study 22408779 — Surrogate Endpoint (SUR): Bone mineral density
Study 12120883 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7790606 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 29220533 — Surrogate Endpoint (SUR): Blood pressure
Study 22271072 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22271072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 498698 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29100199 — Surrogate Endpoint (SUR): Blood pressure
Study 24794093 — Surrogate Endpoint (SUR): Bone mineral density
Study 15204794 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27981552 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 25071075 — Surrogate Endpoint (SUR): Blood pressure
Study 10493664 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 10493664 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8670596 — Surrogate Endpoint (SUR): Bone mineral density
Study 8670596 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2872795 — Surrogate Endpoint (SUR): Blood pressure
Study 30176543 — Predictive Biomarker (PRD): EPHA2 mRNA
Genes: EPHA2; ECK
Study 25352653 — Surrogate Endpoint (SUR): Serum creatinine
Study 21402550 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21402550 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 19858379 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 19858379 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 28389218 — Surrogate Endpoint (SUR): Blood pressure
Study 25591836 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25591836 — Predictive Biomarker (PRD): Hormone receptor
Study 12658367 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19890249 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 19890249 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 19890249 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 11896506 — Surrogate Endpoint (SUR): Blood pressure
Study 58196 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31324360 — Surrogate Endpoint (SUR): Blood pressure
Study 11509799 — Surrogate Endpoint (SUR): Blood pressure
Study 23564914 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25003117 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25003117 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 1450626 — Surrogate Endpoint (SUR): Blood pressure
Study 1450626 — Surrogate Endpoint (SUR): Serum calcium
Study 26549533 — Surrogate Endpoint (SUR): Blood pressure
Study 24672940 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17326083 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 15147247 — Surrogate Endpoint (SUR): Blood pressure
Study 28659181 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 28659181 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17010568 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 17010568 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17010568 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17010568 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17010568 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 2195054 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 25092886 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 17692112 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 15351853 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15351853 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 21545991 — Surrogate Endpoint (SUR): Serum creatinine
Study 11348956 — Surrogate Endpoint (SUR): Serum creatinine
Study 2468896 — Surrogate Endpoint (SUR): Blood pressure
Study 21292873 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 17541211 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 17541211 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11932280 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 11932280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2550046 — Surrogate Endpoint (SUR): Blood pressure
Study 779587 — Surrogate Endpoint (SUR): Blood pressure
Study 1578912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 3935869 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 3935869 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29560543 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24675955 — Surrogate Endpoint (SUR): Blood pressure
Study 12383044 — Surrogate Endpoint (SUR): Blood pressure
Study 10597550 — Surrogate Endpoint (SUR): Blood pressure
Study 15215813 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15215813 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10974371 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8136092 — Surrogate Endpoint (SUR): Blood pressure
Study 20526694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7930659 — Surrogate Endpoint (SUR): Blood pressure
Study 31350828 — Surrogate Endpoint (SUR): Blood pressure
Study 15647189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2090821 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 25761434 — Surrogate Endpoint (SUR): Bone mineral density
Study 24311451 — Surrogate Endpoint (SUR): Blood pressure
Study 22445437 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22445437 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 22445437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15373008 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 2905879 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 17103080 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31354252 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 27140710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27140710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24438754 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 24438754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8771231 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20975106 — Surrogate Endpoint (SUR): Blood pressure
Study 20735823 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 20735823 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 18370541 — Surrogate Endpoint (SUR): Blood pressure
Study 28606961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28606961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11668420 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 31607205 — Surrogate Endpoint (SUR): Blood pressure
Study 31607205 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25539895 — Surrogate Endpoint (SUR): Blood pressure
Study 11252881 — Surrogate Endpoint (SUR): Blood pressure
Study 2551988 — Surrogate Endpoint (SUR): Blood pressure
Study 2551988 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2551988 — Surrogate Endpoint (SUR): Serum potassium
Study 2551988 — Surrogate Endpoint (SUR): Serum creatinine
Study 31175747 — Surrogate Endpoint (SUR): Blood pressure
Study 21644085 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18355812 — Predictive Biomarker (PRD): UPK1B mRNA
Genes: UPK1B; TSPAN20
Study 18355812 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 23939394 — Predictive Biomarker (PRD): CPPED1 mRNA
Genes: CPPED1; CSTP1
Study 23939394 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 19491872 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 10884455 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9356091 — Surrogate Endpoint (SUR): Blood pressure
Study 21251896 — Predictive Biomarker (PRD): NEB mRNA
Genes: NEB
Study 21251896 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 9007717 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 1829918 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28624486 — Surrogate Endpoint (SUR): Blood pressure