TrialPanorama/TrialPanorama-database huggingface dataset:
Study 3386845 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 31512258 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 21534244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21534244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21534244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16548084 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9931882 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24005546 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 9432196 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 22692758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20210368 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 6387286 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25675560 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21917634 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 7305784 — Surrogate Endpoint (SUR): Blood pressure
Study 28273933 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 22257422 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19463133 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19463133 — Surrogate Endpoint (SUR): Blood pressure
Study 17963316 — Surrogate Endpoint (SUR): Blood pressure
Study 15359902 — Surrogate Endpoint (SUR): Blood pressure
Study 7862918 — Surrogate Endpoint (SUR): Blood pressure
Study 2570604 — Surrogate Endpoint (SUR): Blood pressure
Study 79761 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 23672672 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17086470 — Surrogate Endpoint (SUR): Bone mineral density
Study 9217756 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9217756 — Surrogate Endpoint (SUR): Blood pressure
Study 8424508 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27090436 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27090436 — Surrogate Endpoint (SUR): Blood pressure
Study 21849206 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18353618 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 16249698 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study 16249698 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 21967254 — Surrogate Endpoint (SUR): Serum creatinine
Study 19567088 — Predictive Biomarker (PRD): GJB2 mRNA
Genes: GJB2
Study 9669421 — Surrogate Endpoint (SUR): Serum creatinine
Study 21931019 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 10589889 — Surrogate Endpoint (SUR): Blood pressure
Study 25675559 — Surrogate Endpoint (SUR): Blood pressure
Study 10812288 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31757794 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 29733520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19965540 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19965540 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 19965540 — Surrogate Endpoint (SUR): Serum calcium
Study 15864137 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 12645717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24392491 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19253522 — Surrogate Endpoint (SUR): Blood pressure
Study 16012079 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 28067075 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22011265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16089138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16089138 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16089138 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16089138 — Safety Biomarker (SAF): IL-6 and IL-10
Study 29874199 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29874199 — Surrogate Endpoint (SUR): Blood pressure
Study 17461854 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15351193 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2504171 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28712113 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28712113 — Surrogate Endpoint (SUR): Blood pressure
Study 28712113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26158605 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 22067312 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22103452 — Surrogate Endpoint (SUR): Blood pressure
Study 10420149 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 8076658 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11340104 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30203440 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30203440 — Surrogate Endpoint (SUR): Blood pressure
Study 24231272 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 7808833 — Surrogate Endpoint (SUR): Blood pressure
Study 2573295 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29561428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28205449 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 28205449 — Predictive Biomarker (PRD): NTRK2 mRNA
Genes: NTRK2; TRKB
Study 28205449 — Predictive Biomarker (PRD): NTRK
Study 17716779 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 15533546 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15533546 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1741639 — Surrogate Endpoint (SUR): Blood pressure
Study 29433682 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 25706622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25706622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25706622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8936492 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29808819 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22385548 — Safety Biomarker (SAF): RYR1
Genes: RYR; PPP1R137
Study 22385548 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22385548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1305042 — Surrogate Endpoint (SUR): Blood pressure
Study 30872116 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 23764683 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 8989196 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 29602140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29602140 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 29602140 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28606915 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 23830392 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 16781218 — Surrogate Endpoint (SUR): Blood pressure
Study 9844098 — Surrogate Endpoint (SUR): Bone mineral density
Study 7536619 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 6993253 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28835058 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28835058 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 28835058 — Surrogate Endpoint (SUR): Blood pressure
Study 21425738 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21425738 — Safety Biomarker (SAF): Reactive oxygen species
Study 23048018 — Predictive Biomarker (PRD): ENPP2 mRNA
Genes: ENPP2; ATX; PDNP2
Study 10336576 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7482386 — Surrogate Endpoint (SUR): Blood pressure
Study 31368282 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31368282 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 31368282 — Safety Biomarker (SAF): BDNF
Study 21085635 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21085635 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 18635912 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22302887 — Surrogate Endpoint (SUR): Blood pressure
Study 402275 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20353858 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 26385164 — Surrogate Endpoint (SUR): Blood pressure
Study 18417739 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study 12534646 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31018921 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 31018921 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26766564 — Surrogate Endpoint (SUR): Blood pressure
Study 2820626 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25258014 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20722556 — Surrogate Endpoint (SUR): Blood pressure
Study 12823127 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28665937 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 28665937 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 9205017 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9205017 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28679683 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 28679683 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 28679683 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 23505198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23505198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23505198 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 14987325 — Surrogate Endpoint (SUR): Bone mineral density
Study 26659934 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 21869712 — Safety Biomarker (SAF): Hyaluronic acid
Study 16865869 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 10853878 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9115000 — Surrogate Endpoint (SUR): Blood pressure
Study 20144066 — Surrogate Endpoint (SUR): Blood pressure
Study 25824543 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25824543 — Surrogate Endpoint (SUR): Blood pressure
Study 21145923 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29987566 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 29923614 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27311493 — Surrogate Endpoint (SUR): Blood pressure
Study 1335388 — Surrogate Endpoint (SUR): Blood pressure
Study 22747856 — Predictive Biomarker (PRD): DLST mRNA
Genes: DLST; DLTS
Study 18768511 — Safety Biomarker (SAF): MTHFR
Study 10625862 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6517242 — Surrogate Endpoint (SUR): Blood pressure
Study 22441566 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 15672797 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15672797 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 18053317 — Surrogate Endpoint (SUR): Plasma sitosterol and campesterol
Study 1528786 — Surrogate Endpoint (SUR): Blood pressure
Study 26450534 — Surrogate Endpoint (SUR): Blood pressure
Study 3114794 — Surrogate Endpoint (SUR): Blood pressure
Study 17647003 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 17647003 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 17647003 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 10480473 — Surrogate Endpoint (SUR): Blood pressure
Study 26308780 — Surrogate Endpoint (SUR): Blood pressure
Study 19023644 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 19023644 — Predictive Biomarker (PRD): STT3A mRNA
Genes: STT3A; ITM1; TMC
Study 3070032 — Surrogate Endpoint (SUR): Blood pressure
Study 26188211 — Surrogate Endpoint (SUR): Serum creatinine
Study 9109608 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 20358155 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20358155 — Surrogate Endpoint (SUR): Blood pressure
Study 15911935 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 10477530 — Surrogate Endpoint (SUR): Blood pressure
Study 2213375 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17047932 — Surrogate Endpoint (SUR): Blood pressure
Study 9009112 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3107289 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 25437221 — Surrogate Endpoint (SUR): Serum creatinine
Study 7487145 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7487145 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1840344 — Surrogate Endpoint (SUR): Blood pressure
Study 26754343 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 19648157 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19648157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15195212 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 15195212 — Surrogate Endpoint (SUR): Serum calcium
Study 11274903 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11274903 — Surrogate Endpoint (SUR): Blood pressure
Study 9588097 — Surrogate Endpoint (SUR): Blood pressure
Study 1066150 — Predictive Biomarker (PRD): LUC7L3 mRNA
Genes: LUC7L3; CREAP1; CROP; O48
Study 27993829 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 27993829 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 27993829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17213596 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9206057 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2996028 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22592665 — Surrogate Endpoint (SUR): Blood pressure
Study 22592665 — Surrogate Endpoint (SUR): Serum creatinine
Study 20348368 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 18547853 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15805751 — Surrogate Endpoint (SUR): Bone mineral density
Study 10599356 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7551841 — Surrogate Endpoint (SUR): Blood pressure
Study 25227774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23845016 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 21873264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21873264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15104556 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31741136 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28235206 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 29059442 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 23181989 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 14564313 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31367914 — Surrogate Endpoint (SUR): Serum sodium
Study 24448121 — Safety Biomarker (SAF): PRSs score
Study 22512461 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12809960 — Surrogate Endpoint (SUR): Blood pressure
Study 12809960 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12809960 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1797999 — Surrogate Endpoint (SUR): Blood pressure
Study 24297663 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 23207332 — Monitoring Biomarker (MOI): HBV DNA
Study 20709087 — Safety Biomarker (SAF): Reactive oxygen species
Study 20709087 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9088582 — Surrogate Endpoint (SUR): Blood pressure
Study 10792383 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23270288 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 23270288 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 20231536 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15883418 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15883418 — Surrogate Endpoint (SUR): Blood pressure
Study 20339846 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 16522696 — Surrogate Endpoint (SUR): Serum sodium
Study 16522696 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25497694 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23928867 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20708320 — Surrogate Endpoint (SUR): Blood pressure
Study 2659104 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 2659104 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22018187 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 11742887 — Surrogate Endpoint (SUR): Blood pressure
Study 9459076 — Surrogate Endpoint (SUR): Blood pressure
Study 27219124 — Surrogate Endpoint (SUR): Blood pressure
Study 1718694 — Surrogate Endpoint (SUR): Serum creatinine
Study 31294447 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22080021 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31958985 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 24844332 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8399631 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8399631 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3528611 — Surrogate Endpoint (SUR): Serum creatinine
Study 3528611 — Surrogate Endpoint (SUR): Serum potassium
Study 3528611 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31375879 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 12220769 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12220769 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12220769 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23953384 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 23696676 — Surrogate Endpoint (SUR): Blood pressure
Study 18154823 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1547191 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21839467 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 20141565 — Surrogate Endpoint (SUR): Blood pressure
Study 12799091 — Surrogate Endpoint (SUR): Blood pressure
Study 2662830 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 30745260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23604570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23107346 — Surrogate Endpoint (SUR): Blood pressure
Study 18167502 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 16173965 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 30621047 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 30621047 — Predictive Biomarker (PRD): ARG2 mRNA
Genes: ARG2
Study 30621047 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30621047 — Predictive Biomarker (PRD): SUCLG1 mRNA
Genes: SUCLG1
Study 30621047 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 30621047 — Surrogate Endpoint (SUR): Blood pressure
Study 20112368 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18173153 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 1761331 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10633642 — Surrogate Endpoint (SUR): Blood pressure
Study 7546499 — Surrogate Endpoint (SUR): Blood pressure
Study 28060921 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 9611669 — Predictive Biomarker (PRD): TRIM32 mRNA
Genes: TRIM32; HT2A
Study 29735019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27195316 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15986953 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12414399 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15134695 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 11157009 — Predictive Biomarker (PRD): Hormone receptor
Study 9579818 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7991067 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2522008 — Surrogate Endpoint (SUR): Blood pressure
Study 23024150 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT