TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10815894 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30781529 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30781529 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 23017669 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19203899 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17381504 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8383057 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8383057 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 8383057 — Surrogate Endpoint (SUR): Blood pressure
Study 8383057 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21541781 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15121737 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 10419902 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 10419902 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study 10419902 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 31469923 — Safety Biomarker (SAF): Hyaluronic acid
Study 12972673 — Surrogate Endpoint (SUR): Blood pressure
Study 12972673 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12972673 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10973445 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8793044 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 2944434 — Surrogate Endpoint (SUR): Blood pressure
Study 20522841 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15998756 — Surrogate Endpoint (SUR): Blood pressure
Study 6478732 — Surrogate Endpoint (SUR): Blood pressure
Study 9002329 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 1623865 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 18503008 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 12442928 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 227618 — Surrogate Endpoint (SUR): Serum triglycerides
Study 227618 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31688649 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 21970950 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 8181576 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23562364 — Surrogate Endpoint (SUR): Bone mineral density
Study 22417659 — Surrogate Endpoint (SUR): Blood pressure
Study 1357927 — Surrogate Endpoint (SUR): Blood pressure
Study 23155130 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 21059213 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21059213 — Surrogate Endpoint (SUR): Blood pressure
Study 27821644 — Surrogate Endpoint (SUR): Serum uric acid
Study 27821644 — Surrogate Endpoint (SUR): Serum creatinine
Study 25175734 — Surrogate Endpoint (SUR): Blood pressure
Study 24038026 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 24038026 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 20061435 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 6298103 — Surrogate Endpoint (SUR): Blood pressure
Study 30948273 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 6997218 — Surrogate Endpoint (SUR): Blood pressure
Study 15189627 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15189627 — Surrogate Endpoint (SUR): Blood pressure
Study 27335114 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study 15023160 — Surrogate Endpoint (SUR): Serum creatinine
Study 15023160 — Surrogate Endpoint (SUR): Blood pressure
Study 11697809 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 4025156 — Surrogate Endpoint (SUR): Blood pressure
Study 30180806 — Surrogate Endpoint (SUR): Serum sodium
Study 27484436 — Surrogate Endpoint (SUR): Bone mineral density
Study 24263075 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22534814 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 10938493 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10938493 — Surrogate Endpoint (SUR): Serum creatinine
Study 10938493 — Surrogate Endpoint (SUR): Blood pressure
Study 10938493 — Surrogate Endpoint (SUR): Serum uric acid
Study 30895694 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29698955 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29698955 — Surrogate Endpoint (SUR): Blood pressure
Study 29453751 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 16186005 — Surrogate Endpoint (SUR): Blood pressure
Study 7485681 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 26091023 — Surrogate Endpoint (SUR): Blood pressure
Study 18987287 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15978753 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8665771 — Surrogate Endpoint (SUR): Blood pressure
Study 1893805 — Surrogate Endpoint (SUR): Plasma ammonia
Study 30604577 — Surrogate Endpoint (SUR): Blood pressure
Study 23245807 — Surrogate Endpoint (SUR): Blood pressure
Study 11682399 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24289887 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 24289887 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 18427724 — Surrogate Endpoint (SUR): Bone mineral density
Study 3031260 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 26598750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19729663 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1173830 — Surrogate Endpoint (SUR): Blood pressure
Study 31821098 — Surrogate Endpoint (SUR): Serum creatinine
Study 31165710 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 28825957 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 21539680 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21539680 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18997675 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 7484820 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23954997 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 23954997 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 23954997 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 23954997 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 23954997 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 23954997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 23954997 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 23954997 — Predictive Biomarker (PRD): TNFRSF18 mRNA
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study 23954997 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 23954997 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 12957685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11037041 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27488183 — Surrogate Endpoint (SUR): Blood pressure
Study 18297259 — Surrogate Endpoint (SUR): Blood pressure
Study 11865427 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11501128 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30704982 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2851388 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2851388 — Surrogate Endpoint (SUR): Blood pressure
Study 2851388 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2851388 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18777606 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 16108731 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16108731 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 4074614 — Surrogate Endpoint (SUR): Blood pressure
Study 3481635 — Surrogate Endpoint (SUR): Blood pressure
Study 7843782 — Surrogate Endpoint (SUR): Blood pressure
Study 20610229 — Surrogate Endpoint (SUR): Serum creatinine
Study 17262997 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 17262997 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 17262997 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 17262997 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FasL mRNA
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 17262997 — Predictive Biomarker (PRD): FAS mRNA
Genes: FAS; APT1; FAS1; TNFRSF6
Study 8902310 — Surrogate Endpoint (SUR): Blood pressure
Study 8902310 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1511566 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1511566 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30824339 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 22480799 — Surrogate Endpoint (SUR): Blood pressure
Study 20416390 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17651636 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12219782 — Predictive Biomarker (PRD): PITRM1 mRNA
Genes: PITRM1; KIAA1104; MP1; PREP
Study 30369062 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30369062 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28438121 — Surrogate Endpoint (SUR): Blood pressure
Study 24443923 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14694252 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 14694252 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11165421 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11165421 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 7391988 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28029485 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28029485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28029485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26496327 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 24397355 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 11559721 — Safety Biomarker (SAF): Interleukin 12
Study 11559721 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9834891 — Surrogate Endpoint (SUR): Blood pressure
Study 2543223 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2543223 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29255347 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29255347 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19720913 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29114847 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 16110136 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31621838 — Surrogate Endpoint (SUR): Bone mineral density
Study 23706949 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16648502 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3230278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3230278 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 3230278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27312076 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9302491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26780184 — Surrogate Endpoint (SUR): Blood pressure
Study 25172198 — Surrogate Endpoint (SUR): Blood pressure
Study 10869917 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10869917 — Surrogate Endpoint (SUR): Blood pressure
Study 31818329 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 21220471 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21220471 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21220471 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 19728200 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19728200 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10839593 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9387720 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 16387120 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30762290 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 3641693 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21246843 — Surrogate Endpoint (SUR): Blood pressure
Study 22956531 — Surrogate Endpoint (SUR): Blood pressure
Study 18797455 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 16042878 — Monitoring Biomarker (MOI): HBV DNA
Study 11819181 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10574107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31781298 — Safety Biomarker (SAF): miR-1
Study 31781298 — Safety Biomarker (SAF): miR-133a
Study 29426362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25497747 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25497747 — Surrogate Endpoint (SUR): Blood pressure
Study 16014055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7894098 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30308615 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 21992993 — Surrogate Endpoint (SUR): Blood pressure
Study 27450646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27450646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27450646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11479245 — Surrogate Endpoint (SUR): Blood pressure
Study 9340698 — Surrogate Endpoint (SUR): Blood pressure
Study 3789649 — Surrogate Endpoint (SUR): Serum potassium
Study 29354973 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 15018018 — Surrogate Endpoint (SUR): Serum calcium
Study 9402292 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31729108 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29898827 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23908141 — Predictive Biomarker (PRD): MCPH1 mRNA
Genes: MCPH1
Study 23908141 — Predictive Biomarker (PRD): FYN mRNA
Genes: FYN
Study 23908141 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 23908141 — Predictive Biomarker (PRD): PRKCA mRNA
Genes: PRKCA; PKCA; PRKACA
Study 23908141 — Predictive Biomarker (PRD): SNW1 mRNA
Genes: SNW1; SKIIP; SKIP
Study 19322976 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 10507591 — Surrogate Endpoint (SUR): Blood pressure
Study 30044302 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28176386 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 16545510 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 3462423 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3462423 — Surrogate Endpoint (SUR): Blood pressure
Study 24980265 — Surrogate Endpoint (SUR): Blood pressure
Study 17999977 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17999977 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 17999977 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17999977 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14662267 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1528502 — Predictive Biomarker (PRD): ADCY10 mRNA
Genes: ADCY10; SAC
Study 25719429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25719429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25719429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21345843 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8884833 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31820603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22197455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15199625 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15199625 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 15199625 — Predictive Biomarker (PRD): SLURP1 mRNA
Genes: SLURP1; ARS
Study 12173815 — Surrogate Endpoint (SUR): Serum creatinine
Study 12173815 — Safety Biomarker (SAF): Urinary microalbumin
Study 9027784 — Safety Biomarker (SAF): Interleukin 1
Study 28729302 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 10517737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7861022 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23031366 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17453967 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17453967 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31818787 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 3903786 — Surrogate Endpoint (SUR): Blood pressure
Study 24515764 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22140123 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20090545 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9802367 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26012937 — Surrogate Endpoint (SUR): Bone mineral density
Study 22462232 — Monitoring Biomarker (MOI): HBV DNA
Study 3602267 — Surrogate Endpoint (SUR): Blood pressure
Study 30765508 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 26873336 — Surrogate Endpoint (SUR): Blood pressure
Study 2092324 — Surrogate Endpoint (SUR): Serum calcium
Study 24166518 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 24166518 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 3261548 — Surrogate Endpoint (SUR): Blood pressure
Study 31839571 — Surrogate Endpoint (SUR): Blood pressure
Study 27713964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31328463 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 31328463 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22541894 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30076613 — Surrogate Endpoint (SUR): Probing pocket depth
Study 25047649 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 28501736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28501736 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 20836726 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 18312806 — Surrogate Endpoint (SUR): Blood pressure
Study 2497634 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 385023 — Surrogate Endpoint (SUR): Blood pressure
Study 29040119 — Predictive Biomarker (PRD): SECTM1 mRNA
Genes: SECTM1; K12
Study 11517825 — Surrogate Endpoint (SUR): Blood pressure
Study 11517825 — Surrogate Endpoint (SUR): Serum uric acid
Study 27000324 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 18974654 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 7798614 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3044666 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3044666 — Surrogate Endpoint (SUR): Blood pressure
Study 24781571 — Surrogate Endpoint (SUR): Blood pressure
Study 1619996 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6714820 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30064991 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31868987 — Surrogate Endpoint (SUR): Blood pressure
Study 11430552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23986778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21173495 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15070944 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 15070944 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15070944 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15070944 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1