TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10852273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10852273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9165957 — Surrogate Endpoint (SUR): Blood pressure
Study 1376797 — Surrogate Endpoint (SUR): Blood pressure
Study 20230295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17999710 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17999710 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 12891281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12891281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12891281 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18679683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15569821 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15569821 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15569821 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 8912770 — Surrogate Endpoint (SUR): Blood pressure
Study 17460608 — Predictive Biomarker (PRD): SLC12A1 mRNA
Genes: SLC12A1; NKCC2
Study 17460608 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 17460608 — Predictive Biomarker (PRD): SCNN1A mRNA
Genes: SCNN1A; SCNN1
Study 17460608 — Predictive Biomarker (PRD): SCNN1G mRNA
Genes: SCNN1G
Study 9533424 — Surrogate Endpoint (SUR): Blood pressure
Study 8913487 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6193346 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29880491 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29880491 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26366802 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 26366802 — Safety Biomarker (SAF): HLA-DQA1 and HLA-DRB1
Study 26366802 — Safety Biomarker (SAF): HLA-DQA1
Genes: CELIAC1
Study 26366802 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 17156423 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 16840654 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16840654 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12568852 — Predictive Biomarker (PRD): GNRHR mRNA
Genes: GNRHR; GRHR
Study 29945562 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 27776761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27776761 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16219019 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16219019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7979841 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12208924 — Surrogate Endpoint (SUR): Bone mineral density
Study 9485226 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2801583 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2801583 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28584189 — Surrogate Endpoint (SUR): Blood pressure
Study 16868501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11737409 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18155448 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 21822978 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17931721 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 17931721 — Surrogate Endpoint (SUR): Blood pressure
Study 1827023 — Surrogate Endpoint (SUR): Blood pressure
Study 25840580 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 17258568 — Surrogate Endpoint (SUR): Serum creatinine
Study 16287365 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16287365 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 11348602 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9322568 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9322568 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9322568 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 9322568 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7945032 — Predictive Biomarker (PRD): EIF2AK3 mRNA
Genes: EIF2AK3; PEK; PERK
Study 3224091 — Surrogate Endpoint (SUR): Blood pressure
Study 25548141 — Surrogate Endpoint (SUR): Blood pressure
Study 15690319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25887511 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 21414216 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 19568921 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15023243 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30731480 — Surrogate Endpoint (SUR): Serum calcium
Study 30731480 — Surrogate Endpoint (SUR): Bone mineral density
Study 28759939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28759939 — Surrogate Endpoint (SUR): Blood pressure
Study 18284263 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18284263 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18284263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18284263 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 16815774 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 10946033 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10946033 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22916320 — Surrogate Endpoint (SUR): Blood pressure
Study 22916320 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9722035 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28570723 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28570723 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21263322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10783347 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10783347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10783347 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24886228 — Surrogate Endpoint (SUR): Blood pressure
Study 9705684 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7614523 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2203262 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 2203262 — Surrogate Endpoint (SUR): Serum potassium
Study 2203262 — Surrogate Endpoint (SUR): Blood pressure
Study 30630649 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 27163805 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27163805 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24447683 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12679451 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10720847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10720847 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12212211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7138750 — Surrogate Endpoint (SUR): Serum calcium
Study 26625755 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26625755 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 23660274 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21856592 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21856592 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9360784 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3870624 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30318584 — Surrogate Endpoint (SUR): Blood pressure
Study 11165585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28715298 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28715298 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 25381047 — Surrogate Endpoint (SUR): Bone mineral density
Study 19805441 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 15658645 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15658645 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7942624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29222719 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 24888429 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 24888429 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24888429 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24888429 — Surrogate Endpoint (SUR): Blood pressure
Study 24888429 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20207328 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 24525393 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22105813 — Surrogate Endpoint (SUR): Bone mineral density
Study 17509174 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31400933 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 31400933 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 11374853 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11374853 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19218618 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15774778 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 15774778 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study 8704439 — Surrogate Endpoint (SUR): Blood pressure
Study 31903600 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31903600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27856208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25572025 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 7926296 — Safety Biomarker (SAF): Protein AMBP
Genes: AMBP; HCP; ITIL
Study 7926296 — Surrogate Endpoint (SUR): Blood pressure
Study 19950299 — Predictive Biomarker (PRD): CCR1 mRNA
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 28300812 — Predictive Biomarker (PRD): OPRK1 mRNA
Genes: OPRK1; OPRK
Study 28300812 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 28300812 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 28300812 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 28300812 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 28300812 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 28300812 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 21340022 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21340022 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 21340022 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19551860 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 19551860 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 19551860 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19551860 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 19551860 — Predictive Biomarker (PRD): SULT1E1 mRNA
Genes: SULT1E1; STE
Study 19551860 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 9236451 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 3315587 — Surrogate Endpoint (SUR): Blood pressure
Study 18280205 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17009270 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 14717341 — Surrogate Endpoint (SUR): Blood pressure
Study 14717341 — Surrogate Endpoint (SUR): Serum creatinine
Study 31504554 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31504554 — Safety Biomarker (SAF): BDNF
Study 25559612 — Surrogate Endpoint (SUR): Blood pressure
Study 2405737 — Surrogate Endpoint (SUR): Blood pressure
Study 26102639 — Surrogate Endpoint (SUR): Blood pressure
Study 22105872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22105872 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20641098 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 20641098 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 28977399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26242443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26242443 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15240611 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 15240611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19472387 — Predictive Biomarker (PRD): PNN mRNA
Genes: PNN; DRS; MEMA
Study 16954440 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 16954440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16954440 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11773888 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 11773888 — Surrogate Endpoint (SUR): Serum creatinine
Study 9460599 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29933868 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29933868 — Surrogate Endpoint (SUR): Serum uric acid
Study 23682155 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 21114380 — Surrogate Endpoint (SUR): Blood pressure
Study 20128377 — Surrogate Endpoint (SUR): Blood pressure
Study 7712918 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20464480 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14535966 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 14535966 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10891987 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 8938176 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 29247452 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 1634056 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 3966411 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22123705 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 22123705 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22123705 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 31154595 — Surrogate Endpoint (SUR): Blood pressure
Study 28575010 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11211198 — Surrogate Endpoint (SUR): Blood pressure
Study 2663319 — Surrogate Endpoint (SUR): Blood pressure
Study 29129436 — Surrogate Endpoint (SUR): Bone mineral density
Study 8907587 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 28421384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26031321 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 19176684 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19176684 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 21087399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11453955 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11453955 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 16467096 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 16467096 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 27879499 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11795343 — Predictive Biomarker (PRD): ELF3 mRNA
Genes: ELF3; ERT; ESX; JEN
Study 21605000 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 16487434 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 16487434 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16487434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27554378 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 22205309 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 22205309 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10339734 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30885522 — Safety Biomarker (SAF): miR-9
Study 27636018 — Predictive Biomarker (PRD): TACR3 mRNA
Genes: TACR3; NK3R; TAC3R
Study 24831288 — Surrogate Endpoint (SUR): Blood pressure
Study 15965309 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 15965309 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 10822319 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10822319 — Surrogate Endpoint (SUR): Blood pressure
Study 15564986 — Surrogate Endpoint (SUR): Blood pressure
Study 30173287 — Surrogate Endpoint (SUR): Blood pressure
Study 30173287 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26700585 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26700585 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26700585 — Surrogate Endpoint (SUR): Blood pressure
Study 18556337 — Predictive Biomarker (PRD): PTPN22 mRNA
Genes: PTPN22; PTPN8
Study 18556337 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 18556337 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 18556337 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 19687359 — Surrogate Endpoint (SUR): Blood pressure
Study 14759614 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11334895 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 9220209 — Surrogate Endpoint (SUR): Blood pressure
Study 18845330 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11954942 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2209320 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24668358 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 20080287 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20080287 — Surrogate Endpoint (SUR): Blood pressure
Study 23761378 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 18622251 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18622251 — Surrogate Endpoint (SUR): Blood pressure
Study 26682780 — Surrogate Endpoint (SUR): Blood pressure
Study 22846643 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 22846643 — Surrogate Endpoint (SUR): Blood pressure
Study 19996308 — Surrogate Endpoint (SUR): Blood pressure
Study 19996308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19996308 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31389599 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28299764 — Surrogate Endpoint (SUR): Blood pressure
Study 23723317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23723317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17689948 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11205921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9698139 — Surrogate Endpoint (SUR): Bone mineral density
Study 7992446 — Surrogate Endpoint (SUR): Blood pressure
Study 7992446 — Surrogate Endpoint (SUR): Bone mineral density
Study 25599284 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 25599284 — Surrogate Endpoint (SUR): Bone mineral density
Study 30690825 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22031518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22031518 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22031518 — Safety Biomarker (SAF): IL-6 and IL-10