TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01145781 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT02886195 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03969524 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02044029 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT02306954 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00085436 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00646035 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study NCT00646035 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT02465801 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02642952 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05931354 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03965962 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01039948 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04517136 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT00767754 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study NCT03727971 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00089765 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT00089765 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02584829 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT00431444 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04134611 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03392428 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04140786 — Predictive Biomarker (PRD): Laminin subunit alpha-3
Genes: LAMA3; LAMNA
Study NCT04140786 — Predictive Biomarker (PRD): LAMB3 mRNA
Genes: LAMB3; LAMNB1
Study NCT04140786 — Predictive Biomarker (PRD): LAMC2 mRNA
Genes: LAMC2; LAMB2T; LAMNB2
Study NCT02880137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study NCT03015311 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02624258 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03068624 — Predictive Biomarker (PRD): SLC45A2 mRNA
Genes: SLC45A2; AIM1; MATP
Study NCT04105959 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study NCT01152801 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01152801 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05532228 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05762042 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01791621 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00123903 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01522794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02944760 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01918202 — Predictive Biomarker (PRD): PDE10A mRNA
Genes: PDE10A
Study NCT01412125 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01852071 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01852071 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT01852071 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT01232712 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT01232712 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00479635 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study NCT04584398 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00973115 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02320877 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01186549 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00016341 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03017625 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT00869544 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03792620 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT00972023 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02740231 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01869634 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04731948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04731948 — Safety Biomarker (SAF): MTHFR
Study NCT04626011 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT05172635 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05172635 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05172635 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05172635 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02574442 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT04245644 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00725686 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00147485 — Pharmacodynamic Biomarker (PDY): Cyclin-dependent kinase 1
Genes: CDK1; CDC2; CDC28A; CDKN1; P34CDC2
Study NCT02449811 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02449811 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04165967 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT03425734 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01066026 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04286113 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01118858 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01118858 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02708316 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT01367379 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01187654 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study NCT01491646 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03991286 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00204646 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT00767559 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02541461 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02208869 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT02208869 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study NCT02208869 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04310696 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study NCT04310696 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02681653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05001971 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT00854789 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00854789 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00153595 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02258815 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02372253 — Predictive Biomarker (PRD): TXNIP mRNA
Genes: TXNIP; VDUP1
Study NCT01232816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02366676 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02742519 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02742519 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study NCT00088413 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00088413 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT04021446 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04363242 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03638427 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03638427 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01553058 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01553058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01553058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01946659 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02150967 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT02150967 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT02508363 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03964870 — Predictive Biomarker (PRD): RYR1 mRNA
Genes: RYR1; RYDR
Study NCT04083664 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT01127984 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT02236572 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02236572 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00041470 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04791293 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04791293 — Surrogate Endpoint (SUR): Serum sodium
Study NCT06488937 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT06488937 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT06488937 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT06488937 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00191789 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00754689 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03372746 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00493649 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00507338 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT01622868 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01622868 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00105313 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study NCT04464811 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01544855 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01792934 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT04433078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02993627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03356223 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT03356223 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study NCT03356223 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT03971162 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03971162 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00255216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01119066 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00407836 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00973986 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01840748 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT01840748 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT02569463 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01148134 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00493350 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03606915 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03606915 — Safety Biomarker (SAF): BDNF
Study NCT02768545 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study NCT04413838 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02206750 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02250118 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02250118 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00553410 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00765401 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT00643890 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02421185 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT00079846 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01109498 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT02345174 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT02944188 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT03593733 — Safety Biomarker (SAF): Cytochrome c
Study NCT03593733 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03593733 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03806088 — Surrogate Endpoint (SUR): Serum potassium
Study NCT03674814 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study NCT04454151 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT04399577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03197571 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01650948 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00059046 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT00532311 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03146663 — Predictive Biomarker (PRD): NUCB1 mRNA
Genes: NUCB1; NUC
Study NCT00940524 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02850744 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03605264 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03605264 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT00243529 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT02556281 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03433690 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03284567 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03284567 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00541268 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03569358 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02308319 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01981265 — Predictive Biomarker (PRD): CSPG5 mRNA
Genes: CSPG5; CALEB; NGC
Study NCT04738994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04738994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04738994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04738994 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03819387 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01661569 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02895178 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01189630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04565119 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT01007396 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01408524 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02916342 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03774771 — Surrogate Endpoint (SUR): Serum calcium
Study NCT03774771 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT02915627 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00143949 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00077493 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT02479204 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03980496 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT02204982 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01448889 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT01488409 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01041794 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04413916 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study NCT04413916 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-150
Genes: MIR150
Study NCT04413916 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT04413916 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study NCT02231398 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00286624 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study NCT02931175 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02101281 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04431375 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03300492 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT05408273 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03263325 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04008550 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03722381 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03722381 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03417583 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01622400 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03360162 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study NCT03196882 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study NCT03196882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00522782 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00400517 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03484312 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03896854 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04089527 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT02118454 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01643408 — Surrogate Endpoint (SUR): Serum asparaginase
Study NCT02036424 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00304031 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00739531 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00269087 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04237181 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT04237181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03804580 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03804580 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00852007 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT00188617 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03470376 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02515071 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01794858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01794858 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01794858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02919449 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT04147494 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04147494 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT02040831 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01658605 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study NCT00421889 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT03062813 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03062813 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03522415 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01095822 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT04608305 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00937131 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03848572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04873388 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS