TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31605797 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31605797 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 26980210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22770758 — Surrogate Endpoint (SUR): Blood pressure
Study 17662090 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 16380708 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 29945245 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 29782217 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 29782217 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 26556577 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 26556577 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26547499 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 21778673 — Surrogate Endpoint (SUR): Bone mineral density
Study 11268223 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11268223 — Surrogate Endpoint (SUR): Blood pressure
Study 16626957 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25475929 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17135618 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12706934 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12706934 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24491572 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 24491572 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 11704445 — Surrogate Endpoint (SUR): Blood pressure
Study 9627365 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9627365 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3287837 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31166679 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 31166679 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31166679 — Predictive Biomarker (PRD): Hormone receptor
Study 16476114 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16476114 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30585985 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 25891697 — Surrogate Endpoint (SUR): Blood pressure
Study 20964740 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20964740 — Surrogate Endpoint (SUR): Blood pressure
Study 12034517 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12034517 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31586420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30860570 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30860570 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30860570 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21602474 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21602474 — Surrogate Endpoint (SUR): Blood pressure
Study 19635148 — Surrogate Endpoint (SUR): Blood pressure
Study 19635148 — Surrogate Endpoint (SUR): Serum creatinine
Study 12468560 — Surrogate Endpoint (SUR): Blood pressure
Study 29945920 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 29945920 — Predictive Biomarker (PRD): IKZF3 mRNA
Genes: IKZF3; ZNFN1A3
Study 29945920 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 22360996 — Surrogate Endpoint (SUR): Blood pressure
Study 31035054 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31035054 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15878754 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15878754 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25694481 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 25694481 — Surrogate Endpoint (SUR): Blood pressure
Study 23496006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18379535 — Surrogate Endpoint (SUR): Blood pressure
Study 16802519 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8095240 — Surrogate Endpoint (SUR): Blood pressure
Study 20819314 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3138441 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28520754 — Predictive Biomarker (PRD): NFKB1 mRNA
Genes: NFKB1
Study 28520754 — Predictive Biomarker (PRD): NFKB2 mRNA
Genes: NFKB2; LYT10
Study 15593020 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11437859 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11437859 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11437859 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11437859 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25327942 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 20816039 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 18427147 — Surrogate Endpoint (SUR): Bone mineral density
Study 16532712 — Surrogate Endpoint (SUR): Blood pressure
Study 16532712 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16532712 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12692113 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20039429 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 17321816 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 11605744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11605744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11819342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11819342 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30817465 — Surrogate Endpoint (SUR): Blood pressure
Study 25923550 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23889096 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12074359 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24063362 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26617135 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12560435 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18406045 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 3533561 — Surrogate Endpoint (SUR): Blood pressure
Study 25282031 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19607755 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 19607755 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 12189442 — Surrogate Endpoint (SUR): Blood pressure
Study 8596497 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8596497 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1431597 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30368585 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 27169834 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 23101480 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15452671 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23351825 — Surrogate Endpoint (SUR): Blood pressure
Study 17296460 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17296460 — Surrogate Endpoint (SUR): Blood pressure
Study 22248500 — Surrogate Endpoint (SUR): Blood pressure
Study 19070995 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 19070995 — Surrogate Endpoint (SUR): Blood pressure
Study 23587747 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 9204354 — Surrogate Endpoint (SUR): Blood pressure
Study 29236711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12447010 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9583368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9583368 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25837215 — Surrogate Endpoint (SUR): Blood pressure
Study 25837215 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18655566 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 18655566 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 16959188 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6115001 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 31090511 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study 25125635 — Surrogate Endpoint (SUR): Blood pressure
Study 9459393 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16353581 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3356082 — Surrogate Endpoint (SUR): Blood pressure
Study 27752170 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18093197 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12166353 — Surrogate Endpoint (SUR): Blood pressure
Study 2912000 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31128057 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 26329838 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 26329838 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19298231 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 19298231 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19298231 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 28154796 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 25993119 — Predictive Biomarker (PRD): IFNAR1 mRNA
Genes: IFNAR1; IFNAR
Study 21775147 — Surrogate Endpoint (SUR): Bone mineral density
Study 17584698 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 17584698 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17584698 — Surrogate Endpoint (SUR): Blood pressure
Study 15201999 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2227074 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27634419 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 24716610 — Predictive Biomarker (PRD): FGF7 mRNA
Genes: FGF7; KGF
Study 24716610 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24716610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19390327 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15450725 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 15450725 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9746769 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 9746769 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 27271190 — Surrogate Endpoint (SUR): Blood pressure
Study 18572079 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 12903826 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 12903826 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12903826 — Surrogate Endpoint (SUR): Blood pressure
Study 30336598 — Predictive Biomarker (PRD): FER mRNA
Genes: FER; TYK3
Study 11127445 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11127445 — Surrogate Endpoint (SUR): Blood pressure
Study 7746415 — Predictive Biomarker (PRD): PRF1
Genes: PFP; P1; HPLH2
Study 31875053 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28008750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28008750 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28008750 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28008750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19288149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15599835 — Surrogate Endpoint (SUR): Blood pressure
Study 11056773 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11056773 — Surrogate Endpoint (SUR): Blood pressure
Study 2976670 — Surrogate Endpoint (SUR): Blood pressure
Study 16356485 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 16356485 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16356485 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16356485 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16356485 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 16356485 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 16356485 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 16356485 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 16356485 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 16356485 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 16356485 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 8645023 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 8645023 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study 30915366 — Predictive Biomarker (PRD): MSN mRNA
Genes: MSN
Study 20025149 — Surrogate Endpoint (SUR): Blood pressure
Study 17998767 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 1221110 — Surrogate Endpoint (SUR): Blood pressure
Study 15213322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15213322 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 10074978 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 29600390 — Surrogate Endpoint (SUR): Blood pressure
Study 24570327 — Surrogate Endpoint (SUR): Serum creatinine
Study 22024226 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19195791 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 6406654 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29463485 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29463485 — Surrogate Endpoint (SUR): Blood pressure
Study 25614155 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 21508862 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21508862 — Safety Biomarker (SAF): BDNF
Study 15200652 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15200652 — Surrogate Endpoint (SUR): Blood pressure
Study 11158224 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11158224 — Surrogate Endpoint (SUR): Serum creatinine
Study 25534866 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 22088245 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22088245 — Surrogate Endpoint (SUR): Serum testosterone
Study 14506194 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 10202987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7636648 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31685356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31685356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31685356 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21334626 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15145924 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 2897763 — Surrogate Endpoint (SUR): Blood pressure
Study 27472020 — Surrogate Endpoint (SUR): Blood pressure
Study 14734593 — Surrogate Endpoint (SUR): Blood pressure
Study 9469533 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 7940682 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7940682 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28286115 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 17420513 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 15891590 — Surrogate Endpoint (SUR): Bone mineral density
Study 27184784 — Surrogate Endpoint (SUR): Blood pressure
Study 25402666 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22985565 — Surrogate Endpoint (SUR): Bone mineral density
Study 18570599 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 12478147 — Surrogate Endpoint (SUR): Serum testosterone
Study 10718909 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30623236 — Safety Biomarker (SAF): Hyaluronic acid
Study 10511390 — Surrogate Endpoint (SUR): Blood pressure
Study 26437056 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26437056 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26784137 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 20300015 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 18259010 — Surrogate Endpoint (SUR): Blood pressure
Study 11443189 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11443189 — Surrogate Endpoint (SUR): Bone mineral density
Study 11443189 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11443189 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7958119 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3314464 — Surrogate Endpoint (SUR): Blood pressure
Study 31530820 — Surrogate Endpoint (SUR): Blood pressure
Study 31530820 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29946969 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29946969 — Surrogate Endpoint (SUR): Blood pressure
Study 26573073 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12235653 — Predictive Biomarker (PRD): NOCT mRNA
Genes: NOCT; CCR4; CCRN4L; NOC
Study 10460065 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11181810 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8220653 — Predictive Biomarker (PRD): SLC6A7 mRNA
Genes: SLC6A7; PROT
Study 30071838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 8636825 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28931520 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28931520 — Safety Biomarker (SAF): Interleukin 12
Study 21411093 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 21411093 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21411093 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18775100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18775100 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 15770057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15770057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10453777 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 19147974 — Surrogate Endpoint (SUR): Bone mineral density
Study 8993250 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 8181028 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2955799 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29866187 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29866187 — Surrogate Endpoint (SUR): Serum creatinine
Study 20560981 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7979285 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31009834 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 28152251 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 779588 — Surrogate Endpoint (SUR): Blood pressure
Study 28838980 — Safety Biomarker (SAF): APC
Genes: DP2; DP3; DP2.5; PPP1R46
Study 11208880 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1515565 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28089080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7810174 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26271331 — Surrogate Endpoint (SUR): Blood pressure
Study 2412037 — Surrogate Endpoint (SUR): Blood pressure
Study 10870980 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 31200092 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 28403972 — Surrogate Endpoint (SUR): Blood pressure
Study 25450717 — Monitoring Biomarker (MOI): HBV DNA
Study 16186262 — Surrogate Endpoint (SUR): Blood pressure
Study 10769584 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1