TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23727264 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 23727264 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18822906 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14519634 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 14519634 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 1358922 — Surrogate Endpoint (SUR): Blood pressure
Study 29498348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29498348 — Surrogate Endpoint (SUR): Blood pressure
Study 10047624 — Surrogate Endpoint (SUR): Blood pressure
Study 31725473 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 22223180 — Safety Biomarker (SAF): Interleukin 1
Study 25796408 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17160911 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12585144 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2736968 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2736968 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 26086641 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 23941313 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 23941313 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 23941313 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 23941313 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 21623607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21623607 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21623607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21623607 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9234828 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9234828 — Surrogate Endpoint (SUR): Blood pressure
Study 29669529 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 19664210 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15377480 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15377480 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11486241 — Surrogate Endpoint (SUR): Serum uric acid
Study 3394909 — Surrogate Endpoint (SUR): Blood pressure
Study 31971449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28654562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25231109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14980942 — Surrogate Endpoint (SUR): Blood pressure
Study 7633693 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7633693 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 2675377 — Surrogate Endpoint (SUR): Blood pressure
Study 21844392 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14748914 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 14748914 — Surrogate Endpoint (SUR): Blood pressure
Study 14748914 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8125422 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22768459 — Surrogate Endpoint (SUR): Serum creatinine
Study 2081142 — Surrogate Endpoint (SUR): Blood pressure
Study 24075772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19146605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19146605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16567815 — Surrogate Endpoint (SUR): Blood pressure
Study 16380690 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 16380690 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10326147 — Surrogate Endpoint (SUR): Blood pressure
Study 8603632 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 31720795 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28514613 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 21208446 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22564540 — Predictive Biomarker (PRD): PCA3
Study 20150839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20150839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20150839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20150839 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20150839 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11384572 — Surrogate Endpoint (SUR): Blood pressure
Study 31801600 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 31801600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27028190 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 23805979 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23805979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23805979 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 20953959 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 20953959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20953959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20953959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16916668 — Surrogate Endpoint (SUR): Blood pressure
Study 22372531 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 2967184 — Surrogate Endpoint (SUR): Blood pressure
Study 22322195 — Surrogate Endpoint (SUR): Blood pressure
Study 16128472 — Surrogate Endpoint (SUR): Blood pressure
Study 30367647 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 30367647 — Surrogate Endpoint (SUR): Serum creatinine
Study 27605966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27605966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23681396 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 19282169 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 2180861 — Surrogate Endpoint (SUR): Blood pressure
Study 23799528 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 23799528 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 23799528 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 23799528 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 11208222 — Surrogate Endpoint (SUR): Blood pressure
Study 23462343 — Surrogate Endpoint (SUR): Blood pressure
Study 12024594 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8865711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17241859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15896617 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15896617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15896617 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17872899 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 17872899 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7919903 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31988343 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21483491 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19483372 — Surrogate Endpoint (SUR): Bone mineral density
Study 18036365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18036365 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31433518 — Surrogate Endpoint (SUR): Bone mineral density
Study 6387059 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 6387059 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 30523756 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30523756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23157899 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 17622289 — Surrogate Endpoint (SUR): Blood pressure
Study 17622289 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17622289 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11849412 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 11849412 — Predictive Biomarker (PRD): FBN1 mRNA
Genes: FBN1; FBN
Study 14759615 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27136912 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 27136912 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 9186240 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15932840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 9523857 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31448392 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 23730848 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23963438 — Surrogate Endpoint (SUR): Blood pressure
Study 23963438 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20672447 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 17933470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17933470 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 17933470 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 7477217 — Monitoring Biomarker (MOI): HBV DNA
Study 31260548 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 15110370 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15110370 — Surrogate Endpoint (SUR): Blood pressure
Study 19543664 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 15611462 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 11321866 — Surrogate Endpoint (SUR): Blood pressure
Study 8512162 — Surrogate Endpoint (SUR): Blood pressure
Study 27871598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24829298 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 24829298 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20538738 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8005121 — Surrogate Endpoint (SUR): Blood pressure
Study 2511239 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 23333201 — Surrogate Endpoint (SUR): Blood pressure
Study 21666065 — Predictive Biomarker (PRD): UGT2B15 mRNA
Genes: UGT2B15; UGT2B8
Study 16551910 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15142871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1395119 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1395119 — Surrogate Endpoint (SUR): Blood pressure
Study 29138181 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22179955 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 22179955 — Predictive Biomarker (PRD): LYPLAL1 mRNA
Genes: LYPLAL1
Study 22179955 — Predictive Biomarker (PRD): GNPDA2 mRNA
Genes: GNPDA2; GNP2
Study 22179955 — Predictive Biomarker (PRD): NEGR1 mRNA
Genes: NEGR1; IGLON4; UNQ2433/PRO4993
Study 22179955 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 22179955 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 16087822 — Surrogate Endpoint (SUR): Bone mineral density
Study 17997890 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17997890 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9633944 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26226139 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 26226139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9207344 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 3415398 — Surrogate Endpoint (SUR): Blood pressure
Study 12152004 — Surrogate Endpoint (SUR): Blood pressure
Study 7912878 — Surrogate Endpoint (SUR): Blood pressure
Study 31504336 — Surrogate Endpoint (SUR): Blood pressure
Study 31504336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28832978 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28832978 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16810760 — Monitoring Biomarker (MOI): HBV DNA
Study 10707786 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 24452810 — Predictive Biomarker (PRD): CTRC mRNA
Genes: CTRC; CLCR
Study 16286578 — Surrogate Endpoint (SUR): Blood pressure
Study 16286578 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10490723 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24355210 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24355210 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24355210 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21371166 — Surrogate Endpoint (SUR): Blood pressure
Study 17874530 — Surrogate Endpoint (SUR): Blood pressure
Study 9223108 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9223108 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21908036 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 21908036 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21908036 — Surrogate Endpoint (SUR): Blood pressure
Study 10516413 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2248921 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25489056 — Surrogate Endpoint (SUR): Blood pressure
Study 10407503 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28849773 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25670366 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25670366 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17376293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17376293 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17376293 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15199325 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20639391 — Surrogate Endpoint (SUR): Blood pressure
Study 7032533 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 31932201 — Monitoring Biomarker (MOI): HBV DNA
Study 20446847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20446847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9197875 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9197875 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9197875 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23611825 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11095136 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 30909333 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 21300083 — Surrogate Endpoint (SUR): Blood pressure
Study 19583067 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 19583067 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17456491 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8079827 — Surrogate Endpoint (SUR): Bone mineral density
Study 25732417 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 25732417 — Surrogate Endpoint (SUR): Serum creatinine
Study 19067726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19067726 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 19067726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19067726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15142013 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3279725 — Surrogate Endpoint (SUR): Blood pressure
Study 23406684 — Surrogate Endpoint (SUR): Blood pressure
Study 17581217 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17581217 — Surrogate Endpoint (SUR): Blood pressure
Study 15699266 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 15699266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2272957 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16691061 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 11350571 — Surrogate Endpoint (SUR): Blood pressure
Study 29091530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23759461 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12563672 — Safety Biomarker (SAF): Interleukin 1
Study 10100069 — Surrogate Endpoint (SUR): Blood pressure
Study 9156926 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14973308 — Safety Biomarker (SAF): DRD2
Study 7946592 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 2840000 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28940037 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 12388895 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 6237051 — Predictive Biomarker (PRD): INSM1 mRNA
Genes: INSM1; IA1
Study 26048144 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25182544 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24445367 — Surrogate Endpoint (SUR): Serum creatinine
Study 15062908 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 28703374 — Surrogate Endpoint (SUR): Serum creatinine
Study 10866899 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10866899 — Surrogate Endpoint (SUR): Blood pressure
Study 1530680 — Predictive Biomarker (PRD): ACKR1 mRNA
Genes: ACKR1; DARC; FY; GPD
Study 23743487 — Surrogate Endpoint (SUR): Serum sodium
Study 18063490 — Surrogate Endpoint (SUR): Bone mineral density
Study 8603758 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 31714353 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30366971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30366971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30366971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27183835 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 24840045 — Surrogate Endpoint (SUR): Blood pressure
Study 18695931 — Surrogate Endpoint (SUR): Blood pressure
Study 10805546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10805546 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10805546 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10805546 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 2353864 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2353864 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31558739 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 27485237 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 15649287 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 8207741 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16569546 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 16569546 — Surrogate Endpoint (SUR): Blood pressure
Study 9071201 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8369985 — Surrogate Endpoint (SUR): Bone mineral density
Study 3505530 — Surrogate Endpoint (SUR): Forced vital capacity