TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11709366 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28302543 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 28302543 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 28302543 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 15080578 — Surrogate Endpoint (SUR): Blood pressure
Study 12243437 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8109552 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 21569094 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15175795 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 15175795 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11521726 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11521726 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27717405 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 22232134 — Surrogate Endpoint (SUR): Blood pressure
Study 11855559 — Monitoring Biomarker (MOI): HBV DNA
Study 2260546 — Surrogate Endpoint (SUR): Blood pressure
Study 15295 — Surrogate Endpoint (SUR): Blood pressure
Study 19548434 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 17679725 — Predictive Biomarker (PRD): Hormone receptor
Study 15910745 — Predictive Biomarker (PRD): SAA4 mRNA
Genes: SAA4; CSAA
Study 9874055 — Surrogate Endpoint (SUR): Blood pressure
Study 22196835 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17717534 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12441039 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 30328241 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30328241 — Safety Biomarker (SAF): BDNF
Study 2645550 — Surrogate Endpoint (SUR): Blood pressure
Study 29360701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29360701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29360701 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20934573 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 16115151 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 12146000 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 10586564 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 2375291 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 25872126 — Surrogate Endpoint (SUR): Blood pressure
Study 19462320 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15257848 — Surrogate Endpoint (SUR): Blood pressure
Study 21476961 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19593175 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9112219 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9112219 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7901248 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 3306128 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 31820537 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28553078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28553078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28553078 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26169960 — Surrogate Endpoint (SUR): Blood pressure
Study 20393176 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 20393176 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20393176 — Surrogate Endpoint (SUR): Blood pressure
Study 11870127 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9758298 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29883070 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 29883070 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 29883070 — Predictive Biomarker (PRD): RORC mRNA
Genes: RORC; NR1F3; RORG; RZRG
Study 29883070 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 2906290 — Surrogate Endpoint (SUR): Blood pressure
Study 10747531 — Surrogate Endpoint (SUR): Blood pressure
Study 25048074 — Surrogate Endpoint (SUR): Bone mineral density
Study 16193197 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12642354 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10590183 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9081272 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15860465 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 9510492 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23381968 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 19453846 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 29179781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29179781 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29179781 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 29179781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26069170 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19368788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9133547 — Surrogate Endpoint (SUR): Blood pressure
Study 7883836 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 10576237 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30900158 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30900158 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 10892523 — Surrogate Endpoint (SUR): Blood pressure
Study 8808432 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 8403157 — Surrogate Endpoint (SUR): Blood pressure
Study 26818228 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26818228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20448287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1826095 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1826095 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30683848 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30683848 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30683848 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study 29524536 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27377073 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30476963 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28209169 — Predictive Biomarker (PRD): VIT mRNA
Genes: VIT; UNQ647/PRO1277
Study 20107201 — Predictive Biomarker (PRD): NR1I2 mRNA
Genes: NR1I2; PXR
Study 19736596 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12768117 — Surrogate Endpoint (SUR): Blood pressure
Study 10705267 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27270872 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22014381 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22014381 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 22014381 — Predictive Biomarker (PRD): Hormone receptor
Study 22014381 — Surrogate Endpoint (SUR): Bone mineral density
Study 12621741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12621741 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7582060 — Surrogate Endpoint (SUR): Blood pressure
Study 2476039 — Surrogate Endpoint (SUR): Blood pressure
Study 17597037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17597037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11799368 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11799368 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31053570 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29089038 — Surrogate Endpoint (SUR): Serum creatinine
Study 29089038 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23350584 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19223168 — Surrogate Endpoint (SUR): Blood pressure
Study 8076921 — Surrogate Endpoint (SUR): Bone mineral density
Study 2676651 — Surrogate Endpoint (SUR): Blood pressure
Study 25797356 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11726433 — Surrogate Endpoint (SUR): Serum creatinine
Study 29257028 — Safety Biomarker (SAF): Hyaluronic acid
Study 27322401 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18723437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12830992 — Surrogate Endpoint (SUR): Serum creatinine
Study 9591486 — Surrogate Endpoint (SUR): Bone mineral density
Study 31418989 — Surrogate Endpoint (SUR): Blood pressure
Study 25808980 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23506356 — Safety Biomarker (SAF): Hyaluronic acid
Study 21679977 — Surrogate Endpoint (SUR): Bone mineral density
Study 18507878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18507878 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15327191 — Surrogate Endpoint (SUR): Blood pressure
Study 8218764 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 31675478 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31675478 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18217460 — Surrogate Endpoint (SUR): Blood pressure
Study 11207173 — Surrogate Endpoint (SUR): Serum sodium
Study 7872728 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29635505 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22927555 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15869351 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 10598762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1936753 — Surrogate Endpoint (SUR): Blood pressure
Study 26432128 — Safety Biomarker (SAF): Hyaluronic acid
Study 23567660 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9500689 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2186630 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2186630 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12796126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12796126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12796126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10666136 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31212365 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29425373 — Surrogate Endpoint (SUR): Blood pressure
Study 27529510 — Surrogate Endpoint (SUR): Urinary oxalate
Study 17397435 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17719472 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 14764771 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 14764771 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15019739 — Surrogate Endpoint (SUR): Bacterial count
Study 9486679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23564803 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6123760 — Surrogate Endpoint (SUR): Blood pressure
Study 31054140 — Safety Biomarker (SAF): Reactive oxygen species
Study 26086066 — Safety Biomarker (SAF): Reactive oxygen species
Study 26086066 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23841265 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 19339779 — Predictive Biomarker (PRD): DCN mRNA
Genes: DCN; SLRR1B
Study 19339779 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 7911921 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 7911921 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25451890 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25451890 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22061864 — Surrogate Endpoint (SUR): Bone mineral density
Study 12921554 — Surrogate Endpoint (SUR): Blood pressure
Study 9383256 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28317149 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 28317149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28317149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28317149 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28317149 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28317149 — Predictive Biomarker (PRD): MSR1 mRNA
Genes: MSR1; SCARA1
Study 28317149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24105694 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24105694 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 3685399 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3289598 — Surrogate Endpoint (SUR): Blood pressure
Study 23457535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23457535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23457535 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21273177 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19446148 — Surrogate Endpoint (SUR): Bone mineral density
Study 7021992 — Surrogate Endpoint (SUR): Blood pressure
Study 29508046 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 28692723 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 16681480 — Surrogate Endpoint (SUR): Serum testosterone
Study 15566420 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 11406907 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11406907 — Surrogate Endpoint (SUR): Blood pressure
Study 3277436 — Surrogate Endpoint (SUR): Blood pressure
Study 27993154 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 27993154 — Safety Biomarker (SAF): Hyaluronic acid
Study 24872223 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 24324573 — Monitoring Biomarker (MOI): HBV DNA
Study 18929735 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20182022 — Surrogate Endpoint (SUR): Blood pressure
Study 20182022 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18303097 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2170963 — Surrogate Endpoint (SUR): Blood pressure
Study 1091391 — Surrogate Endpoint (SUR): Serum triglycerides
Study 25581612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19930853 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27501928 — Surrogate Endpoint (SUR): Blood pressure
Study 20586028 — Predictive Biomarker (PRD): SERPINB3 mRNA
Genes: SERPINB3; SCCA; SCCA1
Study 20586028 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20586028 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 10516450 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7492123 — Surrogate Endpoint (SUR): Serum creatinine
Study 1958445 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 1958445 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31868632 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23734250 — Surrogate Endpoint (SUR): Blood pressure
Study 7589011 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 7589011 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7589011 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1771612 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17261960 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11772811 — Surrogate Endpoint (SUR): Blood pressure
Study 2672898 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15975314 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27403931 — Predictive Biomarker (PRD): FMO3 mRNA
Genes: FMO3
Study 27403931 — Predictive Biomarker (PRD): UGT2B15 mRNA
Genes: UGT2B15; UGT2B8
Study 27403931 — Predictive Biomarker (PRD): CYP51A1 mRNA
Genes: CYP51A1; CYP51
Study 16460244 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 8354894 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8354894 — Safety Biomarker (SAF): Interleukin 1
Study 30891654 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 25992488 — Surrogate Endpoint (SUR): Blood pressure
Study 25992488 — Surrogate Endpoint (SUR): Serum uric acid
Study 25992488 — Surrogate Endpoint (SUR): Serum potassium
Study 16960515 — Surrogate Endpoint (SUR): Blood pressure
Study 7948054 — Surrogate Endpoint (SUR): Blood pressure
Study 28192629 — Surrogate Endpoint (SUR): Serum potassium
Study 15232813 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9609271 — Surrogate Endpoint (SUR): Blood pressure
Study 7611580 — Surrogate Endpoint (SUR): Blood pressure
Study 2794058 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11680667 — Surrogate Endpoint (SUR): Blood pressure
Study 27702747 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 27702747 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24500611 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19777316 — Surrogate Endpoint (SUR): Bone mineral density
Study 10098761 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22997780 — Surrogate Endpoint (SUR): Blood pressure
Study 16350718 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10438352 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2253196 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7114512 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7114512 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30933867 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 26375599 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 25086636 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25086636 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 25086636 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-210
Genes: MIR210
Study 17244786 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11706524 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11706524 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 3591644 — Predictive Biomarker (PRD): TNFSF14 mRNA
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study 27746370 — Predictive Biomarker (PRD): PDPN mRNA
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 8581790 — Surrogate Endpoint (SUR): Blood pressure
Study 21334033 — Surrogate Endpoint (SUR): Blood pressure
Study 17721096 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17721096 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 14994390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11773161 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30442551 — Surrogate Endpoint (SUR): Blood pressure
Study 24378475 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22765978 — Predictive Biomarker (PRD): CPOX mRNA
Genes: CPOX; CPO; CPX
Study 18066957 — Surrogate Endpoint (SUR): Blood pressure
Study 11907350 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 28844508 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22647413 — Surrogate Endpoint (SUR): Blood pressure
Study 10471565 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 10471565 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 10471565 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 8853530 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 31877117 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 26543357 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23601899 — Safety Biomarker (SAF): RYR1
Genes: RYR; PPP1R137
Study 16990660 — Surrogate Endpoint (SUR): Blood pressure
Study 7899678 — Surrogate Endpoint (SUR): Blood pressure
Study 19806358 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19806358 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14658397 — Surrogate Endpoint (SUR): Blood pressure
Study 9853926 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 7863813 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2488472 — Surrogate Endpoint (SUR): Serum calcium