TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21936956 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21936956 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25644388 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25644388 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25644388 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9292253 — Surrogate Endpoint (SUR): Blood pressure
Study 29166130 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 27190009 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 27190009 — Safety Biomarker (SAF): DRD2
Study 20375907 — Surrogate Endpoint (SUR): Blood pressure
Study 8733877 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 1706531 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 21798863 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 16964364 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9394314 — Surrogate Endpoint (SUR): Blood pressure
Study 9312762 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9312762 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9312762 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 9312762 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7589029 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 24398649 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study 22568596 — Surrogate Endpoint (SUR): Blood pressure
Study 19710188 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 802071 — Surrogate Endpoint (SUR): Blood pressure
Study 26529159 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21809439 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 21809439 — Safety Biomarker (SAF): Reactive oxygen species
Study 21809439 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8755685 — Surrogate Endpoint (SUR): Blood pressure
Study 1389702 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29678772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29678772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27126487 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25159234 — Surrogate Endpoint (SUR): Blood pressure
Study 22479327 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 22479327 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28338180 — Surrogate Endpoint (SUR): Blood pressure
Study 24167370 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 12577420 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9264433 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8221271 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29663363 — Predictive Biomarker (PRD): TAFA4 mRNA
Genes: TAFA4; FAM19A4
Study 18662629 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30586113 — Surrogate Endpoint (SUR): Blood pressure
Study 30586113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30586113 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30586113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23139215 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 23139215 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 23139215 — Predictive Biomarker (PRD): SIGIRR mRNA
Genes: SIGIRR; UNQ301/PRO342
Study 18386615 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 18386615 — Surrogate Endpoint (SUR): Serum creatinine
Study 18386615 — Surrogate Endpoint (SUR): Serum sodium
Study 6222710 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6222710 — Surrogate Endpoint (SUR): Serum creatinine
Study 27457968 — Surrogate Endpoint (SUR): Blood pressure
Study 24468081 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 11008920 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 11008920 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 23430667 — Surrogate Endpoint (SUR): Blood pressure
Study 18029165 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10800878 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30579763 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27825009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21180275 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22029980 — Safety Biomarker (SAF): Interleukin 12
Study 11598313 — Pharmacodynamic Biomarker (PDY): Neuromodulin
Genes: GAP43
Study 21968267 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 16864930 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9416409 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 21041815 — Surrogate Endpoint (SUR): Serum uric acid
Study 2636645 — Surrogate Endpoint (SUR): Blood pressure
Study 24817417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20298399 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16621879 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1937993 — Surrogate Endpoint (SUR): Blood pressure
Study 30607616 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 11789275 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11789275 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 1312233 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 1312233 — Surrogate Endpoint (SUR): Blood pressure
Study 24637789 — Surrogate Endpoint (SUR): Blood pressure
Study 10344365 — Surrogate Endpoint (SUR): Blood pressure
Study 7047170 — Surrogate Endpoint (SUR): Blood pressure
Study 21946121 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10052667 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10052667 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26585118 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study 8141177 — Surrogate Endpoint (SUR): Serum creatinine
Study 31047956 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25468387 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 25468387 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20957342 — Surrogate Endpoint (SUR): Blood pressure
Study 16912060 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 26270341 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 11023927 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10677983 — Predictive Biomarker (PRD): IL17RD mRNA
Genes: IL17RD; IL17RLM; SEF; UNQ6115/PRO20026
Study 10677983 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 7699214 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24782115 — Safety Biomarker (SAF): Interleukin 1
Study 19957031 — Monitoring Biomarker (MOI): HBV DNA
Study 12957441 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 12957441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12957441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12957441 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29193350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29193350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27508851 — Surrogate Endpoint (SUR): Blood pressure
Study 15673390 — Surrogate Endpoint (SUR): Blood pressure
Study 10549839 — Surrogate Endpoint (SUR): Blood pressure
Study 8524727 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8524727 — Surrogate Endpoint (SUR): Blood pressure
Study 1837120 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7073460 — Surrogate Endpoint (SUR): Blood pressure
Study 27737408 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 22708952 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28452620 — Surrogate Endpoint (SUR): Blood pressure
Study 19308439 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17308218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11577835 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11577835 — Surrogate Endpoint (SUR): Blood pressure
Study 8942398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 8942398 — Predictive Biomarker (PRD): SLC2A5 mRNA
Genes: SLC2A5; GLUT5
Study 8942398 — Safety Biomarker (SAF): Cytochrome c
Study 30378203 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 18812670 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 2736420 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2736420 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16513447 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15568664 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 23898989 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21120297 — Surrogate Endpoint (SUR): Blood pressure
Study 26741127 — Surrogate Endpoint (SUR): Blood pressure
Study 22585090 — Surrogate Endpoint (SUR): Serum calcium
Study 17469105 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 17469105 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 17469105 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 17469105 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 24176784 — Surrogate Endpoint (SUR): Blood pressure
Study 18575447 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 16542200 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9189734 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 1337458 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25560366 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 22296034 — Predictive Biomarker (PRD): PAX4 mRNA
Genes: PAX4
Study 19018143 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19018143 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19018143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31894028 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 29273067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27107326 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18188711 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18188711 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 6129364 — Surrogate Endpoint (SUR): Blood pressure
Study 12844392 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 16146546 — Surrogate Endpoint (SUR): Serum creatinine
Study 16146546 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8873109 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 23982929 — Predictive Biomarker (PRD): NCF4 mRNA
Genes: NCF4; SH3PXD4
Study 22751874 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17389290 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23799356 — Surrogate Endpoint (SUR): Bone mineral density
Study 17684468 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9577944 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23915518 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23915518 — Surrogate Endpoint (SUR): Serum potassium
Study 15149872 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15149872 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31284794 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 16368364 — Surrogate Endpoint (SUR): Blood pressure
Study 12736396 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12736396 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10733466 — Predictive Biomarker (PRD): PLA2G7
Genes: PAFAH; LDL-PLA2
Study 31079509 — Surrogate Endpoint (SUR): Bone mineral density
Study 31079509 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23735472 — Predictive Biomarker (PRD): DCLRE1C mRNA
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study 16213468 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 11772293 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 11772293 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7954528 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 24674654 — Predictive Biomarker (PRD): TMPRSS13 mRNA
Genes: TMPRSS13; MSP; TMPRSS11
Study 20216560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31493178 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 31493178 — Predictive Biomarker (PRD): SLC35A2 mRNA
Genes: SLC35A2; UGALT; UGT; UGTL
Study 29400671 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 15505487 — Surrogate Endpoint (SUR): Blood pressure
Study 20160654 — Surrogate Endpoint (SUR): Blood pressure
Study 656778 — Surrogate Endpoint (SUR): Blood pressure
Study 25869385 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 25869385 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 23110683 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23110683 — Surrogate Endpoint (SUR): Blood pressure
Study 16137049 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 16137049 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 29085969 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 24673716 — Surrogate Endpoint (SUR): Serum creatinine
Study 18614570 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18614570 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10428307 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 10428307 — Surrogate Endpoint (SUR): Blood pressure
Study 7026693 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17445751 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15117727 — Surrogate Endpoint (SUR): Blood pressure
Study 30157771 — Surrogate Endpoint (SUR): Blood pressure
Study 26796612 — Surrogate Endpoint (SUR): Blood pressure
Study 15975103 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15975103 — Surrogate Endpoint (SUR): Blood pressure
Study 14703409 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 14703409 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 14703409 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14703409 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10350103 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31309232 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9440565 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 9440565 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 25956613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25956613 — Safety Biomarker (SAF): Hyaluronic acid
Study 25956613 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 12419715 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 9195520 — Surrogate Endpoint (SUR): Serum creatinine
Study 27676085 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 27676085 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27676085 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 27676085 — Surrogate Endpoint (SUR): Serum calcium
Study 28685934 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 22883036 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 22883036 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22883036 — Surrogate Endpoint (SUR): Blood pressure
Study 15642701 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 8647062 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 1972313 — Surrogate Endpoint (SUR): Blood pressure
Study 116856 — Surrogate Endpoint (SUR): Blood pressure
Study 31830014 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 28692531 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 31853550 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 26553692 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 19052197 — Predictive Biomarker (PRD): TPH2 mRNA
Genes: TPH2; NTPH
Study 6263072 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6263072 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31074791 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31074791 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12616104 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12616104 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8345498 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20409671 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 195201 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30768860 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 9718051 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9718051 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24441734 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 19234720 — Predictive Biomarker (PRD): PDE4B mRNA
Genes: PDE4B; DPDE4
Study 18184536 — Surrogate Endpoint (SUR): Blood pressure
Study 15369506 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24903985 — Surrogate Endpoint (SUR): Blood pressure
Study 16385751 — Surrogate Endpoint (SUR): Bone mineral density
Study 8584072 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 19875761 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 12019107 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30096107 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 23829785 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22563020 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22563020 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15732871 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9805219 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9805219 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3963 — Surrogate Endpoint (SUR): Blood pressure
Study 10988186 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29793595 — Surrogate Endpoint (SUR): Blood pressure
Study 31183378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1899776 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22211798 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22211798 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22211798 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21258125 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16255377 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 3121928 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18500609 — Surrogate Endpoint (SUR): Blood pressure
Study 12939207 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1365017 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26473281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26473281 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26473281 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 24496805 — Surrogate Endpoint (SUR): Blood pressure
Study 20158620 — Surrogate Endpoint (SUR): Blood pressure
Study 31227390 — Surrogate Endpoint (SUR): Bone mineral density
Study 18922851 — Safety Biomarker (SAF): Human leucocyte antigen
Study 18922851 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12660387 — Surrogate Endpoint (SUR): Blood pressure
Study 29728334 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 23788684 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27091532 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 27091532 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 27091532 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15314976 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16103328 — Surrogate Endpoint (SUR): Serum creatinine
Study 12065555 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 26063677 — Surrogate Endpoint (SUR): Blood pressure
Study 22772328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17111305 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11697810 — Surrogate Endpoint (SUR): Bone mineral density
Study 18219225 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF