TrialPanorama/TrialPanorama-database huggingface dataset:
Study 3687352 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23494740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23494740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15077311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15077311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30857413 — Surrogate Endpoint (SUR): Blood pressure
Study 28475671 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23725524 — Surrogate Endpoint (SUR): Blood pressure
Study 21355147 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15372846 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15372846 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27450232 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 27450232 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 9589658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9589658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28629896 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15007119 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 11095452 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29488152 — Predictive Biomarker (PRD): GPR119 mRNA
Genes: GPR119
Study 29488152 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18768350 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8198761 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 23197780 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23197780 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 1948094 — Surrogate Endpoint (SUR): Blood pressure
Study 29653 — Surrogate Endpoint (SUR): Blood pressure
Study 29653 — Surrogate Endpoint (SUR): Serum potassium
Study 9562282 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23792241 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21884956 — Surrogate Endpoint (SUR): Blood pressure
Study 19844206 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 19844206 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 19844206 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 19844206 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 19844206 — Predictive Biomarker (PRD): CRHR1 mRNA
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 19844206 — Predictive Biomarker (PRD): NTRK2 mRNA
Genes: NTRK2; TRKB
Study 15311218 — Surrogate Endpoint (SUR): Blood pressure
Study 9369265 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2417834 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30923187 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 27178047 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20473771 — Surrogate Endpoint (SUR): Blood pressure
Study 18331607 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 18331607 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8550116 — Surrogate Endpoint (SUR): Blood pressure
Study 8550116 — Surrogate Endpoint (SUR): Serum creatinine
Study 6175830 — Surrogate Endpoint (SUR): Blood pressure
Study 19689661 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 2145232 — Surrogate Endpoint (SUR): Blood pressure
Study 6994778 — Surrogate Endpoint (SUR): Blood pressure
Study 17719313 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8306750 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 11422002 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9288700 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9288700 — Surrogate Endpoint (SUR): Blood pressure
Study 29363465 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 22926209 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 12520632 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 24560350 — Surrogate Endpoint (SUR): Bone mineral density
Study 9701721 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9081959 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 28383410 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28383410 — Monitoring Biomarker (MOI): HBV DNA
Study 9377663 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 3082023 — Surrogate Endpoint (SUR): Serum creatinine
Study 27091420 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 20816593 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20816593 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16162696 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 7856527 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31648501 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31648501 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22172912 — Safety Biomarker (SAF): Hyaluronic acid
Study 10972645 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 10972645 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 27512975 — Surrogate Endpoint (SUR): Blood pressure
Study 23947915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22713691 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 22713691 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 22713691 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 22713691 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 22713691 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 20495139 — Surrogate Endpoint (SUR): Blood pressure
Study 22024027 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 30560426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28459958 — Surrogate Endpoint (SUR): Blood pressure
Study 22384550 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22384550 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16679088 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15018289 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9726810 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 9726810 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31230881 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20229041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20229041 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20229041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20229041 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 8778004 — Predictive Biomarker (PRD): ASPA mRNA
Genes: ASPA; ACY2; ASP
Study 28877913 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18695440 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16109110 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 9495394 — Predictive Biomarker (PRD): MTA2 mRNA
Genes: MTA2; MTA1L1; PID
Study 27089361 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27089361 — Surrogate Endpoint (SUR): Blood pressure
Study 31837559 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 29282633 — Surrogate Endpoint (SUR): Blood pressure
Study 20955776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20955776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16781295 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 8916812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8916812 — Safety Biomarker (SAF): Interleukin 1
Study 6819898 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 6819898 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 6819898 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 19317825 — Surrogate Endpoint (SUR): Blood pressure
Study 14747781 — Surrogate Endpoint (SUR): Blood pressure
Study 12659397 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 6791396 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27563883 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27563883 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14623061 — Surrogate Endpoint (SUR): Bone mineral density
Study 11003744 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29650408 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 8817830 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 3908316 — Surrogate Endpoint (SUR): Blood pressure
Study 29953338 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 29146277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27825007 — Predictive Biomarker (PRD): Hormone receptor
Study 11015162 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30820995 — Surrogate Endpoint (SUR): Serum potassium
Study 16239318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16239318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12672915 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10751252 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 3946247 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3946247 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3946247 — Surrogate Endpoint (SUR): Serum triglycerides
Study 14558182 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19056590 — Predictive Biomarker (PRD): KLK3 mRNA
Genes: KLK3; APS
Study 761953 — Surrogate Endpoint (SUR): Blood pressure
Study 27168361 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 17969366 — Surrogate Endpoint (SUR): Blood pressure
Study 10416208 — Predictive Biomarker (PRD): SERPINF2 mRNA
Genes: SERPINF2; AAP; PLI
Study 31588793 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31588793 — Surrogate Endpoint (SUR): Serum creatinine
Study 14634144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14634144 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1768504 — Surrogate Endpoint (SUR): Blood pressure
Study 17906429 — Surrogate Endpoint (SUR): Bacterial count
Study 8026027 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8026027 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25568167 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21190985 — Surrogate Endpoint (SUR): Blood pressure
Study 26547718 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 24740826 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12603500 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12603500 — Surrogate Endpoint (SUR): Blood pressure
Study 12603500 — Surrogate Endpoint (SUR): Serum creatinine
Study 12603500 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8228195 — Surrogate Endpoint (SUR): Blood pressure
Study 29597007 — Surrogate Endpoint (SUR): Serum uric acid
Study 26617202 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19664302 — Surrogate Endpoint (SUR): Blood pressure
Study 6316307 — Surrogate Endpoint (SUR): Blood pressure
Study 31996395 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 31996395 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 24366622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24366622 — Surrogate Endpoint (SUR): Bone mineral density
Study 19419318 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 25749595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25749595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25749595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14719181 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7707113 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 30810254 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 30810254 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 3653591 — Surrogate Endpoint (SUR): Blood pressure
Study 26598077 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17870419 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16254130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16254130 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 10920215 — Surrogate Endpoint (SUR): Bone mineral density
Study 1342819 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 31786864 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 31786864 — Monitoring Biomarker (MOI): HBV DNA
Study 28007205 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24528892 — Monitoring Biomarker (MOI): Procalcitonin
Study 20709517 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12536496 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 12536496 — Safety Biomarker (SAF): Hyaluronic acid
Study 7962520 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 7962520 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 3034372 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25090617 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 25090617 — Surrogate Endpoint (SUR): Blood pressure
Study 1306814 — Surrogate Endpoint (SUR): Blood pressure
Study 25813205 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 19744223 — Surrogate Endpoint (SUR): Serum creatinine
Study 18577791 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 7548458 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 31402509 — Surrogate Endpoint (SUR): Bone mineral density
Study 29685019 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25288325 — Surrogate Endpoint (SUR): Blood pressure
Study 17656445 — Surrogate Endpoint (SUR): Blood pressure
Study 3918196 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29231609 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 29231609 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 21992464 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 21992464 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 18328929 — Surrogate Endpoint (SUR): Blood pressure
Study 18328929 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17283866 — Surrogate Endpoint (SUR): Blood pressure
Study 29687877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29687877 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11770035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8318411 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8318411 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28728785 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 26715485 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17884346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17884346 — Safety Biomarker (SAF): Interleukin 1
Study 12126522 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21876564 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14985946 — Surrogate Endpoint (SUR): Bone mineral density
Study 6391562 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3830240 — Surrogate Endpoint (SUR): Blood pressure
Study 29722834 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22168539 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22168539 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8752186 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29796851 — Safety Biomarker (SAF): Hyaluronic acid
Study 25317619 — Surrogate Endpoint (SUR): Serum creatinine
Study 19602993 — Surrogate Endpoint (SUR): Blood pressure
Study 1359258 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16438370 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16438370 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 16438370 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 2331082 — Surrogate Endpoint (SUR): Blood pressure
Study 27564431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25947165 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16352812 — Predictive Biomarker (PRD): Liver iron
Study 16352812 — Surrogate Endpoint (SUR): Serum creatinine
Study 15197438 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9252775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9252775 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 7543781 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 24598503 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 24598503 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 17697262 — Safety Biomarker (SAF): Hyaluronic acid
Study 17620074 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 10553822 — Surrogate Endpoint (SUR): Blood pressure
Study 26537198 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15145970 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15145970 — Surrogate Endpoint (SUR): Blood pressure
Study 11586054 — Surrogate Endpoint (SUR): Blood pressure
Study 28914446 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 28914446 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23177481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23177481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23177481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18261575 — Surrogate Endpoint (SUR): Bone mineral density
Study 16645021 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24801218 — Predictive Biomarker (PRD): PDE9A mRNA
Genes: PDE9A
Study 24801218 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 2149280 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24880619 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19836952 — Predictive Biomarker (PRD): Hormone receptor
Study 16872374 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16872374 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20205490 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19119599 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 3163364 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9181655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20584776 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 15815935 — Predictive Biomarker (PRD): CRAT mRNA
Genes: CRAT; CAT1
Study 15815935 — Predictive Biomarker (PRD): PDIA3 mRNA
Genes: PDIA3; ERP57; ERP60; GRP58
Study 15815935 — Predictive Biomarker (PRD): SLC22A5 mRNA
Genes: SLC22A5; OCTN2
Study 15815935 — Predictive Biomarker (PRD): CPT1B mRNA
Genes: CPT1B; KIAA1670