TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23861381 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 20224007 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 10229128 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 10229128 — Pharmacodynamic Biomarker (PDY): Peripheral myelin protein 22
Genes: PMP22; GAS3
Study 31801679 — Surrogate Endpoint (SUR): Blood pressure
Study 31801679 — Surrogate Endpoint (SUR): Serum potassium
Study 21632811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8857677 — Surrogate Endpoint (SUR): Serum creatinine
Study 27669457 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 22248749 — Surrogate Endpoint (SUR): Blood pressure
Study 22248749 — Surrogate Endpoint (SUR): Serum creatinine
Study 9626770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8070481 — Surrogate Endpoint (SUR): Blood pressure
Study 8070481 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7936364 — Predictive Biomarker (PRD): NCAM1 mRNA
Genes: NCAM1; NCAM
Study 26364532 — Surrogate Endpoint (SUR): Blood pressure
Study 23884826 — Surrogate Endpoint (SUR): Blood pressure
Study 15848527 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 27491605 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 25331468 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20522795 — Surrogate Endpoint (SUR): Blood pressure
Study 1725913 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17609246 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 16306249 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 7790689 — Surrogate Endpoint (SUR): Serum creatinine
Study 29023536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29023536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17355745 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17355745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17355745 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11465656 — Surrogate Endpoint (SUR): Blood pressure
Study 9779342 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2861315 — Surrogate Endpoint (SUR): Blood pressure
Study 30404626 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 17555385 — Surrogate Endpoint (SUR): Blood pressure
Study 16378069 — Surrogate Endpoint (SUR): Serum creatinine
Study 2460291 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 27634224 — Surrogate Endpoint (SUR): Serum creatinine
Study 27634224 — Surrogate Endpoint (SUR): Blood pressure
Study 27634224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20059570 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20059570 — Surrogate Endpoint (SUR): Blood pressure
Study 10406358 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25329201 — Safety Biomarker (SAF): MTHFR
Study 23155345 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8848515 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31284490 — Surrogate Endpoint (SUR): Blood pressure
Study 31284490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31284490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31284490 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22678961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22678961 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 12052850 — Surrogate Endpoint (SUR): Blood pressure
Study 16781788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21511218 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 18383517 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16595223 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26809009 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 23083841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8726592 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8726592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 6326784 — Surrogate Endpoint (SUR): Blood pressure
Study 30983953 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 25293442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25293442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25293442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25293442 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17468667 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30282142 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27784733 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16288616 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 7797058 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 16030053 — Surrogate Endpoint (SUR): Serum calcium
Study 8955458 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 6181324 — Surrogate Endpoint (SUR): Blood pressure
Study 31489467 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 31489467 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 31489467 — Surrogate Endpoint (SUR): Bone mineral density
Study 31489467 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17585081 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 26509817 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18206857 — Surrogate Endpoint (SUR): Blood pressure
Study 10845350 — Surrogate Endpoint (SUR): Blood pressure
Study 1610539 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6428899 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20447535 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 29077149 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29077149 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16717081 — Surrogate Endpoint (SUR): Serum potassium
Study 16717081 — Surrogate Endpoint (SUR): Serum sodium
Study 15259286 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3901389 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31675674 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 9554186 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 23735647 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23735647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22270380 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20604937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18354383 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18354383 — Surrogate Endpoint (SUR): Blood pressure
Study 12149529 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12149529 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12149529 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 12149529 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 10102256 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10102256 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10102256 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10102256 — Surrogate Endpoint (SUR): Blood pressure
Study 8589555 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20705512 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 2109195 — Surrogate Endpoint (SUR): Serum creatinine
Study 29576354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31334927 — Safety Biomarker (SAF): Hyaluronic acid
Study 26774526 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 26635308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26635308 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12655280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12655280 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31369662 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27806900 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 21600128 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18655554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18655554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14502007 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10918470 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10918470 — Surrogate Endpoint (SUR): Serum uric acid
Study 3145964 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26224751 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 24877660 — Surrogate Endpoint (SUR): Serum creatinine
Study 24877660 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24877660 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20512414 — Monitoring Biomarker (MOI): HBV DNA
Study 16078322 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10636369 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 15704046 — Surrogate Endpoint (SUR): Bone mineral density
Study 4072939 — Surrogate Endpoint (SUR): Blood pressure
Study 30404563 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 30404563 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23670794 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8200250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28851800 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 11374850 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11374850 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1377484 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 6085377 — Surrogate Endpoint (SUR): Blood pressure
Study 31427869 — Safety Biomarker (SAF): Reactive oxygen species
Study 20618359 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12463482 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6758935 — Surrogate Endpoint (SUR): Blood pressure
Study 24743431 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24743431 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22052941 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 22052941 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 22052941 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 22052941 — Predictive Biomarker (PRD): S100A4 mRNA
Genes: S100A4; CAPL; MTS1
Study 22052941 — Predictive Biomarker (PRD): SERPINB9 mRNA
Genes: SERPINB9; PI9
Study 22052941 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 22052941 — Predictive Biomarker (PRD): CTSL mRNA
Genes: CTSL; CTSL1
Study 22052941 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 22052941 — Predictive Biomarker (PRD): PAEP mRNA
Genes: PAEP
Study 22052941 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 22052941 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 2572266 — Surrogate Endpoint (SUR): Blood pressure
Study 49737 — Surrogate Endpoint (SUR): Blood pressure
Study 22093054 — Safety Biomarker (SAF): Hyaluronic acid
Study 12766641 — Surrogate Endpoint (SUR): Blood pressure
Study 9291200 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21122063 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21122063 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21122063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18209255 — Surrogate Endpoint (SUR): Blood pressure
Study 10886123 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8419226 — Surrogate Endpoint (SUR): Blood pressure
Study 8419226 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11176812 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 31159778 — Surrogate Endpoint (SUR): Blood pressure
Study 10750252 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18924048 — Surrogate Endpoint (SUR): Blood pressure
Study 16858168 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31449915 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 31449915 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 8126533 — Surrogate Endpoint (SUR): Blood pressure
Study 2550402 — Surrogate Endpoint (SUR): Serum testosterone
Study 21956711 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 21956711 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 19930832 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 8699777 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8699777 — Surrogate Endpoint (SUR): Blood pressure
Study 23676961 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21886816 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16606934 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 8287573 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8287573 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 27210844 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 21178836 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 14627860 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14627860 — Surrogate Endpoint (SUR): Bone mineral density
Study 10746534 — Surrogate Endpoint (SUR): Blood pressure
Study 30326952 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 590301 — Surrogate Endpoint (SUR): Blood pressure
Study 27495295 — Surrogate Endpoint (SUR): Blood pressure
Study 10542973 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16723326 — Predictive Biomarker (PRD): AGL mRNA
Genes: AGL; GDE
Study 26123704 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 26123704 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 26123704 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 26123704 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26123704 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26123704 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12795787 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 12795787 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29428872 — Surrogate Endpoint (SUR): Serum creatinine
Study 17208410 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 28844118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28844118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23644901 — Surrogate Endpoint (SUR): Blood pressure
Study 27255431 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23777741 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23777741 — Predictive Biomarker (PRD): Hormone receptor
Study 16909131 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11302007 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8841501 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8841501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8841501 — Safety Biomarker (SAF): IL-6 and IL-10
Study 1623898 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25695403 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 25695403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14753029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14753029 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 14753029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14753029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7669532 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 26079649 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 16555056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16555056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16555056 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24999798 — Surrogate Endpoint (SUR): Blood pressure
Study 14694498 — Surrogate Endpoint (SUR): Serum creatinine
Study 31238631 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 31238631 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study 17005278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8287640 — Surrogate Endpoint (SUR): Blood pressure
Study 30053162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25110439 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12374234 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23563442 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 23563442 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23563442 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 1560429 — Surrogate Endpoint (SUR): Blood pressure
Study 2865150 — Surrogate Endpoint (SUR): Blood pressure
Study 30698629 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 22450428 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22450428 — Surrogate Endpoint (SUR): Blood pressure
Study 26551637 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 20595645 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20595645 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20595645 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18006422 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 10870037 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10870037 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 30394834 — Surrogate Endpoint (SUR): Blood pressure
Study 30394834 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27531132 — Surrogate Endpoint (SUR): Blood pressure
Study 6344591 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 30097364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26022945 — Surrogate Endpoint (SUR): Blood pressure
Study 23143842 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15918064 — Safety Biomarker (SAF): Hyaluronic acid
Study 14633753 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14633753 — Surrogate Endpoint (SUR): Blood pressure
Study 17890860 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 8068212 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30050655 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30050655 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 30050655 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 24734285 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 20110249 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 18427279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1