TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15833934 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 31023524 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 9531028 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 30869182 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30869182 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29162572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 23736109 — Surrogate Endpoint (SUR): Blood pressure
Study 10832071 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10832071 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 25613938 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25613938 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21807052 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11120907 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29442148 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29442148 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 25668998 — Surrogate Endpoint (SUR): Serum creatinine
Study 24622263 — Surrogate Endpoint (SUR): Blood pressure
Study 20834187 — Surrogate Endpoint (SUR): Blood pressure
Study 11124689 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11124689 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30277862 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 30277862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16444998 — Predictive Biomarker (PRD): GRAMD4 mRNA
Genes: GRAMD4; DIP; KIAA0767
Study 29728286 — Surrogate Endpoint (SUR): Blood pressure
Study 29753321 — Monitoring Biomarker (MOI): Procalcitonin
Study 10821130 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10821130 — Surrogate Endpoint (SUR): Blood pressure
Study 26136534 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 21550532 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 17805217 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 29202568 — Safety Biomarker (SAF): Hyaluronic acid
Study 26518870 — Surrogate Endpoint (SUR): Blood pressure
Study 26518870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19748675 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7719394 — Surrogate Endpoint (SUR): Blood pressure
Study 31550958 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 28847206 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 28847206 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16696911 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2433653 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 24754065 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1326165 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22243564 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18581941 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25662861 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10611136 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 29381993 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21208909 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21208909 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 21208909 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21208909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1359998 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1359998 — Surrogate Endpoint (SUR): Blood pressure
Study 460026 — Surrogate Endpoint (SUR): Blood pressure
Study 20805430 — Surrogate Endpoint (SUR): Serum creatinine
Study 18279051 — Safety Biomarker (SAF): Interleukin 1
Study 18279051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15689918 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 6320622 — Surrogate Endpoint (SUR): Blood pressure
Study 25895948 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 25895948 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 22735869 — Surrogate Endpoint (SUR): Blood pressure
Study 16350383 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9857535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12858356 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12858356 — Predictive Biomarker (PRD): TGFB1I1 mRNA
Genes: TGFB1I1; ARA55
Study 10928252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10928252 — Safety Biomarker (SAF): IL-6 and IL-10
Study 27383395 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 14764424 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3492975 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22890910 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 16642920 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 1279288 — Surrogate Endpoint (SUR): Blood pressure
Study 29459468 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23404724 — Surrogate Endpoint (SUR): Blood pressure
Study 18057480 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8875379 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8875379 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31335805 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27187101 — Predictive Biomarker (PRD): RAB11FIP1 mRNA
Genes: RAB11FIP1; RCP
Study 22522918 — Monitoring Biomarker (MOI): HBV DNA
Study 20127230 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21161742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21161742 — Safety Biomarker (SAF): Interleukin 1
Study 31838148 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 26125923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26125923 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26125923 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 22775239 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 21156319 — Surrogate Endpoint (SUR): Blood pressure
Study 29900565 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 29900565 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 24325778 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24325778 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23038702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19301936 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19301936 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19301936 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21529957 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12451325 — Surrogate Endpoint (SUR): Blood pressure
Study 2172178 — Surrogate Endpoint (SUR): Blood pressure
Study 30477789 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 20575400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10824236 — Surrogate Endpoint (SUR): Bone mineral density
Study 25339455 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 22678562 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18188658 — Surrogate Endpoint (SUR): Bone mineral density
Study 12029990 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2455141 — Surrogate Endpoint (SUR): Blood pressure
Study 11004028 — Surrogate Endpoint (SUR): Blood pressure
Study 23635012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23635012 — Surrogate Endpoint (SUR): Blood pressure
Study 23635012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23635012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17058225 — Monitoring Biomarker (MOI): HBV DNA
Study 9475650 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9475650 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 2239903 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20729619 — Monitoring Biomarker (MOI): HBV DNA
Study 6112411 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29454587 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29454587 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24134405 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24134405 — Safety Biomarker (SAF): BDNF
Study 1670591 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6606153 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 20380653 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 20380653 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 20380653 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8214416 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 24206869 — Surrogate Endpoint (SUR): Bone mineral density
Study 16009884 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10069556 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 9700034 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15366324 — Surrogate Endpoint (SUR): Blood pressure
Study 14992906 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31095973 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 21088862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29286560 — Surrogate Endpoint (SUR): Bone mineral density
Study 28043418 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 18805335 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 7951008 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30120478 — Surrogate Endpoint (SUR): Blood pressure
Study 20096399 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18202581 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10943584 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 26259517 — Surrogate Endpoint (SUR): Blood pressure
Study 19583742 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 11059637 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8729667 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 1362888 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 30425105 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 30425105 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 19289623 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17239712 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9132031 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 20686900 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12521655 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 22948416 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12700707 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12959290 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 3475429 — Surrogate Endpoint (SUR): Blood pressure
Study 17921381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16140232 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20428608 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 20428608 — Surrogate Endpoint (SUR): Blood pressure
Study 18803991 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 6662724 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28122931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25689146 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 8252492 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21791491 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21791491 — Surrogate Endpoint (SUR): Blood pressure
Study 3276865 — Surrogate Endpoint (SUR): Blood pressure
Study 26047957 — Surrogate Endpoint (SUR): Blood pressure
Study 24018103 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 2417648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26858092 — Surrogate Endpoint (SUR): Blood pressure
Study 23545909 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18405146 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 7560474 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7141686 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 4056259 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29461654 — Surrogate Endpoint (SUR): Blood pressure
Study 16791287 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16791287 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30445718 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 12823643 — Safety Biomarker (SAF): Reactive oxygen species
Study 12823643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10910802 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8955969 — Surrogate Endpoint (SUR): Blood pressure
Study 16281062 — Surrogate Endpoint (SUR): Serum uric acid
Study 16281062 — Surrogate Endpoint (SUR): Blood pressure
Study 8605558 — Surrogate Endpoint (SUR): Serum creatinine
Study 4087290 — Surrogate Endpoint (SUR): Blood pressure
Study 29740768 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 19295388 — Surrogate Endpoint (SUR): Blood pressure
Study 15055251 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15055251 — Surrogate Endpoint (SUR): Blood pressure
Study 30653262 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30653262 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23295789 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 15645954 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15645954 — Surrogate Endpoint (SUR): Blood pressure
Study 15645954 — Surrogate Endpoint (SUR): Serum creatinine
Study 15645954 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15645954 — Surrogate Endpoint (SUR): Serum potassium
Study 30184091 — Surrogate Endpoint (SUR): Blood pressure
Study 23184077 — Surrogate Endpoint (SUR): Serum creatinine
Study 20352618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25623462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25623462 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 25623462 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22827780 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22827780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22827780 — Surrogate Endpoint (SUR): Blood pressure
Study 9702472 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 25974723 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 18445174 — Surrogate Endpoint (SUR): Blood pressure
Study 16564934 — Surrogate Endpoint (SUR): Serum creatinine
Study 1536441 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20566677 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 12528325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12528325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8124121 — Surrogate Endpoint (SUR): Blood pressure
Study 28651927 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8362997 — Surrogate Endpoint (SUR): Blood pressure
Study 12078939 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9698776 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9698776 — Surrogate Endpoint (SUR): Blood pressure
Study 30629187 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30629187 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 30629187 — Surrogate Endpoint (SUR): Blood pressure
Study 28396887 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 28396887 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24339703 — Surrogate Endpoint (SUR): Blood pressure
Study 24339703 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16844625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16844625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16844625 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12727963 — Surrogate Endpoint (SUR): Blood pressure
Study 8853138 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31587950 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24639426 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 24639426 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 1512341 — Surrogate Endpoint (SUR): Blood pressure
Study 6421013 — Surrogate Endpoint (SUR): Blood pressure
Study 27041244 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27041244 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27041244 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22010847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22010847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22010847 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20467879 — Surrogate Endpoint (SUR): Blood pressure
Study 17880478 — Surrogate Endpoint (SUR): Blood pressure
Study 17880478 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10402248 — Predictive Biomarker (PRD): Microsatellite instability
Study 8626261 — Surrogate Endpoint (SUR): Serum creatinine
Study 29179666 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29179666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29179666 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24828621 — Surrogate Endpoint (SUR): Blood pressure
Study 9599191 — Surrogate Endpoint (SUR): Bone mineral density
Study 8023348 — Surrogate Endpoint (SUR): Blood pressure
Study 21518686 — Surrogate Endpoint (SUR): Serum creatinine
Study 29731160 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 23859303 — Surrogate Endpoint (SUR): Blood pressure
Study 8087937 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31779056 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 29851024 — Surrogate Endpoint (SUR): Blood pressure
Study 26293163 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 22961832 — Surrogate Endpoint (SUR): Blood pressure
Study 18559291 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 3970647 — Surrogate Endpoint (SUR): Blood pressure
Study 20232751 — Safety Biomarker (SAF): Reactive oxygen species
Study 10412269 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 10412269 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 10412269 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 28498207 — Safety Biomarker (SAF): Hyaluronic acid
Study 23748819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11906645 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11906645 — Surrogate Endpoint (SUR): Serum creatinine
Study 10958254 — Surrogate Endpoint (SUR): Blood pressure
Study 3209716 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 3209716 — Surrogate Endpoint (SUR): Blood pressure