TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19481079 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10414879 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24025143 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17161227 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17161227 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17161227 — Surrogate Endpoint (SUR): Blood pressure
Study 2514653 — Surrogate Endpoint (SUR): Blood pressure
Study 18306243 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 11177402 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9638980 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 24206823 — Surrogate Endpoint (SUR): Blood pressure
Study 24206823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24206823 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 22309805 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22309805 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31393082 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 19531592 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19531592 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 19531592 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 17569044 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 15104197 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24804483 — Surrogate Endpoint (SUR): Bone mineral density
Study 20167686 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1575169 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1575169 — Surrogate Endpoint (SUR): Blood pressure
Study 3918178 — Surrogate Endpoint (SUR): Sperm parameters
Study 29872803 — Predictive Biomarker (PRD): PTPRC
Genes: LCA; T200; GP180
Study 27048871 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 27048871 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27048871 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 27048871 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25254489 — Surrogate Endpoint (SUR): Serum creatinine
Study 25254489 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21717449 — Predictive Biomarker (PRD): Hormone receptor
Study 19521657 — Surrogate Endpoint (SUR): Bone mineral density
Study 7719245 — Predictive Biomarker (PRD): ZBTB16 mRNA
Genes: ZBTB16; PLZF; ZNF145
Study 29969577 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25629739 — Surrogate Endpoint (SUR): Blood pressure
Study 22899580 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 16396729 — Surrogate Endpoint (SUR): Blood pressure
Study 8465834 — Surrogate Endpoint (SUR): Blood pressure
Study 23017329 — Surrogate Endpoint (SUR): Blood pressure
Study 17140874 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 11580868 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 8427339 — Surrogate Endpoint (SUR): Blood pressure
Study 22152750 — Surrogate Endpoint (SUR): Blood pressure
Study 19307994 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 16391383 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9711053 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 15893170 — Surrogate Endpoint (SUR): Blood pressure
Study 22358586 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 20850365 — Surrogate Endpoint (SUR): Bone mineral density
Study 10331614 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 10331614 — Predictive Biomarker (PRD): FMR1
Genes: FMRP; FRAXA; MGC87458
Study 10331614 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2186058 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2186058 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 11820148 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 11820148 — Surrogate Endpoint (SUR): Blood pressure
Study 1695314 — Surrogate Endpoint (SUR): Blood pressure
Study 28988307 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 9718120 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31627408 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31627408 — Safety Biomarker (SAF): BDNF
Study 31627408 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2537003 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12477770 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12477770 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11022927 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8792046 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 22614887 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18841263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18841263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18841263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18841263 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 18841263 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11834429 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31744060 — Surrogate Endpoint (SUR): Blood pressure
Study 28915283 — Safety Biomarker (SAF): Hyaluronic acid
Study 23112214 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 8487239 — Surrogate Endpoint (SUR): Bone mineral density
Study 29227377 — Surrogate Endpoint (SUR): Blood pressure
Study 22237061 — Surrogate Endpoint (SUR): Serum calcium
Study 22237061 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 1900687 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 21602517 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21602517 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 19105762 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15470331 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 15470331 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25904602 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 19087569 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 14626640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12032039 — Safety Biomarker (SAF): Reactive oxygen species
Study 31151363 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 31151363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31151363 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23021318 — Surrogate Endpoint (SUR): Blood pressure
Study 21921285 — Predictive Biomarker (PRD): Hormone receptor
Study 29992150 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 29992150 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 7554782 — Surrogate Endpoint (SUR): Blood pressure
Study 27992063 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 19463396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19463396 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17462482 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11452676 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9684851 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26431823 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 8362533 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31865333 — Surrogate Endpoint (SUR): Blood pressure
Study 31865333 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31865333 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28233944 — Surrogate Endpoint (SUR): Blood pressure
Study 25957544 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 15956010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10803472 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 17227905 — Safety Biomarker (SAF): XRCC1
Genes: RCC
Study 17227905 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2659995 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31228618 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 28378301 — Surrogate Endpoint (SUR): Blood pressure
Study 18930987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29330660 — Surrogate Endpoint (SUR): Blood pressure
Study 31913578 — Surrogate Endpoint (SUR): Blood pressure
Study 28169880 — Surrogate Endpoint (SUR): Blood pressure
Study 20179652 — Predictive Biomarker (PRD): F2R mRNA
Genes: F2R; CF2R; PAR1; TR
Study 19907103 — Surrogate Endpoint (SUR): Blood pressure
Study 10644808 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10644808 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 10644808 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10644808 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10644808 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 30770758 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30770758 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30770758 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 30770758 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30770758 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30770758 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23945460 — Surrogate Endpoint (SUR): Blood pressure
Study 17534246 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12904193 — Surrogate Endpoint (SUR): Blood pressure
Study 7854171 — Surrogate Endpoint (SUR): Blood pressure
Study 6801079 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27001281 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25494175 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 25510746 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21036778 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19044214 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 6345421 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22938660 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22938660 — Surrogate Endpoint (SUR): Serum creatinine
Study 18441457 — Surrogate Endpoint (SUR): Blood pressure
Study 15915547 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10606114 — Surrogate Endpoint (SUR): Blood pressure
Study 6114503 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29578880 — Surrogate Endpoint (SUR): Blood pressure
Study 23925451 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18335328 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 10500005 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8961085 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8961085 — Surrogate Endpoint (SUR): Blood pressure
Study 12911553 — Surrogate Endpoint (SUR): Blood pressure
Study 31676303 — Surrogate Endpoint (SUR): Blood pressure
Study 31676303 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31676303 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31676303 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24551257 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 8340055 — Monitoring Biomarker (MOI): HBV DNA
Study 23259002 — Surrogate Endpoint (SUR): Blood pressure
Study 18183613 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 28029189 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 23441809 — Surrogate Endpoint (SUR): Blood pressure
Study 15799932 — Predictive Biomarker (PRD): RITA1 mRNA
Genes: RITA1; C12orf52; RITA; PSEC0043
Study 10902462 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 3799443 — Surrogate Endpoint (SUR): Blood pressure
Study 28549637 — Surrogate Endpoint (SUR): Bone mineral density
Study 18617377 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12729523 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10671303 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8841206 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8841206 — Surrogate Endpoint (SUR): Blood pressure
Study 31560700 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25130226 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 19328268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19328268 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11046101 — Surrogate Endpoint (SUR): Blood pressure
Study 9333103 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23100282 — Predictive Biomarker (PRD): CELSR2 mRNA
Genes: CELSR2; CDHF10; EGFL2; KIAA0279; MEGF3
Study 23100282 — Predictive Biomarker (PRD): PSRC1 mRNA
Genes: PSRC1; DDA3; FP3214
Study 23100282 — Predictive Biomarker (PRD): SORT1 mRNA
Genes: SORT1
Study 23100282 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 23100282 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23100282 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 18647814 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18647814 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 10675071 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10675071 — Surrogate Endpoint (SUR): Blood pressure
Study 30529836 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 23532306 — Surrogate Endpoint (SUR): Blood pressure
Study 22152650 — Surrogate Endpoint (SUR): Blood pressure
Study 22152650 — Surrogate Endpoint (SUR): Serum uric acid
Study 19013235 — Surrogate Endpoint (SUR): Blood pressure
Study 15047035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12501759 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 9798587 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23665965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15280342 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 15280342 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 11204586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11204586 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11204586 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9458824 — Surrogate Endpoint (SUR): Blood pressure
Study 2973132 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28786220 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11349388 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 9203655 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7960505 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7960505 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7960505 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7960505 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29248711 — Predictive Biomarker (PRD): TKT mRNA
Genes: TKT
Study 9416930 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 9416930 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30598522 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-150
Genes: MIR150
Study 30598522 — Safety Biomarker (SAF): miR-15a
Genes: MIR15A
Study 30598522 — Safety Biomarker (SAF): miR-375
Genes: MIR375
Study 30598522 — Safety Biomarker (SAF): miR-30a-5p
Genes: MIR30A
Study 3513269 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18837799 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10931123 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 2942844 — Surrogate Endpoint (SUR): Blood pressure
Study 9661091 — Surrogate Endpoint (SUR): Blood pressure
Study 23439744 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23439744 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8380131 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 31074654 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 30684325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30684325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30684325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 241600 — Surrogate Endpoint (SUR): Serum uric acid
Study 29313279 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 29313279 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 29313279 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 16137951 — Surrogate Endpoint (SUR): Bone mineral density
Study 30297258 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 20593910 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 10588452 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 10588452 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 10588452 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 31267366 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 17699311 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31298927 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 18198311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18198311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9101424 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21998703 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9284985 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 8367775 — Predictive Biomarker (PRD): SFPQ mRNA
Genes: SFPQ; PSF
Study 24521021 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 20510247 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20510247 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10910856 — Surrogate Endpoint (SUR): Blood pressure
Study 3924617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 30908082 — Predictive Biomarker (PRD): IL1R2 mRNA
Genes: IL1R2; IL1RB
Study 30908082 — Predictive Biomarker (PRD): ITGB3 mRNA
Genes: ITGB3; GP3A
Study 30908082 — Predictive Biomarker (PRD): CAVIN2 mRNA
Genes: CAVIN2; SDPR
Study 30908082 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 30908082 — Predictive Biomarker (PRD): ZBTB16 mRNA
Genes: ZBTB16; PLZF; ZNF145
Study 30908082 — Predictive Biomarker (PRD): DDIT4 mRNA
Genes: DDIT4; REDD1; RTP801
Study 26016363 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 28929560 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22235821 — Surrogate Endpoint (SUR): Blood pressure
Study 9875835 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31796073 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31796073 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 31796073 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31796073 — Predictive Biomarker (PRD): Hormone receptor
Study 27194364 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26027861 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 26027861 — Safety Biomarker (SAF): Hyaluronic acid
Study 27982478 — Surrogate Endpoint (SUR): Bone mineral density
Study 12770652 — Surrogate Endpoint (SUR): Blood pressure
Study 8886294 — Surrogate Endpoint (SUR): Blood pressure
Study 23408763 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 23408763 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10942162 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2994698 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2994698 — Surrogate Endpoint (SUR): Blood pressure
Study 2994698 — Surrogate Endpoint (SUR): Serum potassium
Study 26924770 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 24809264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24809264 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24809264 — Surrogate Endpoint (SUR): Serum creatinine
Study 22340541 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22340541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22340541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2