TrialPanorama/TrialPanorama-database huggingface dataset:
Study 2194029 — Surrogate Endpoint (SUR): Blood pressure
Study 18930646 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14751650 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14751650 — Surrogate Endpoint (SUR): Blood pressure
Study 8453190 — Surrogate Endpoint (SUR): Bone mineral density
Study 21169142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10364782 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 22796064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21476029 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 30292589 — Surrogate Endpoint (SUR): Serum creatinine
Study 26848931 — Surrogate Endpoint (SUR): Blood pressure
Study 22943927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11477926 — Surrogate Endpoint (SUR): Blood pressure
Study 18334528 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 18334528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18334528 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12571210 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 1680600 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 25926410 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 15648502 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 30863047 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24899597 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15836660 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29450988 — Safety Biomarker (SAF): Hyaluronic acid
Study 19640384 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19640384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9811286 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9811286 — Surrogate Endpoint (SUR): Blood pressure
Study 7815239 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7815239 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27881709 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24351803 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24351803 — Surrogate Endpoint (SUR): Blood pressure
Study 27117531 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20617288 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12450890 — Surrogate Endpoint (SUR): Blood pressure
Study 12450890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23051949 — Surrogate Endpoint (SUR): Blood pressure
Study 23051949 — Surrogate Endpoint (SUR): Serum sodium
Study 9792309 — Surrogate Endpoint (SUR): Serum creatinine
Study 9613405 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9613405 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3450519 — Surrogate Endpoint (SUR): Blood pressure
Study 3450519 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20507651 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8704690 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15046711 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20834105 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20834105 — Monitoring Biomarker (MOI): HBV DNA
Study 17982752 — Surrogate Endpoint (SUR): Sperm parameters
Study 10392481 — Surrogate Endpoint (SUR): Blood pressure
Study 1652386 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31740551 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 28371488 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 28371488 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 24094827 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24094827 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 24094827 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 14762496 — Surrogate Endpoint (SUR): Blood pressure
Study 29703606 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29703606 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 8699054 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30941562 — Surrogate Endpoint (SUR): Serum testosterone
Study 27055643 — Surrogate Endpoint (SUR): Blood pressure
Study 19462315 — Predictive Biomarker (PRD): INSR mRNA
Genes: INSR
Study 17468814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2468957 — Surrogate Endpoint (SUR): Blood pressure
Study 25746399 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16966303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25214069 — Surrogate Endpoint (SUR): Bone mineral density
Study 18813412 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17059329 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8337206 — Surrogate Endpoint (SUR): Blood pressure
Study 30048006 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 30048006 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27797708 — Surrogate Endpoint (SUR): Blood pressure
Study 19880291 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17912634 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17912634 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17912634 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17912634 — Predictive Biomarker (PRD): Hormone receptor
Study 17912634 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12070712 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12070712 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12070712 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8828743 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3913273 — Surrogate Endpoint (SUR): Blood pressure
Study 10480474 — Surrogate Endpoint (SUR): Blood pressure
Study 28325826 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 28325826 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28325826 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 30015629 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 24610876 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25231632 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18654768 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 3946803 — Surrogate Endpoint (SUR): Blood pressure
Study 25792707 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 20545389 — Surrogate Endpoint (SUR): Blood pressure
Study 15692526 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12942146 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 10333102 — Predictive Biomarker (PRD): CTSD mRNA
Genes: CTSD; CPSD
Study 19279561 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 17192761 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 17192761 — Surrogate Endpoint (SUR): Blood pressure
Study 2403834 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31127818 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26011337 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30251598 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30251598 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30251598 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 30251598 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 30251598 — Predictive Biomarker (PRD): HTR2C mRNA
Genes: HTR2C; HTR1C
Study 30251598 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 25427999 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 25427999 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 25427999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25427999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25427999 — Predictive Biomarker (PRD): TICAM1 mRNA
Genes: TICAM1; PRVTIRB; TRIF
Study 25427999 — Predictive Biomarker (PRD): IRF7 mRNA
Genes: IRF7
Study 25427999 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 25427999 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 18487886 — Surrogate Endpoint (SUR): Blood pressure
Study 11641316 — Surrogate Endpoint (SUR): Blood pressure
Study 9410284 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 25777669 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24366034 — Surrogate Endpoint (SUR): Blood pressure
Study 23158073 — Surrogate Endpoint (SUR): Blood pressure
Study 20490904 — Surrogate Endpoint (SUR): Blood pressure
Study 16113620 — Surrogate Endpoint (SUR): Blood pressure
Study 1653660 — Surrogate Endpoint (SUR): Blood pressure
Study 6344265 — Surrogate Endpoint (SUR): Blood pressure
Study 26400416 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22828556 — Surrogate Endpoint (SUR): Blood pressure
Study 10780242 — Surrogate Endpoint (SUR): Blood pressure
Study 31270740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31270740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31270740 — Safety Biomarker (SAF): IL-6 and IL-10
Study 25403582 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21314924 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 11132749 — Surrogate Endpoint (SUR): Blood pressure
Study 8406060 — Surrogate Endpoint (SUR): Blood pressure
Study 21840915 — Surrogate Endpoint (SUR): Blood pressure
Study 9408302 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31148210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20186843 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25047825 — Surrogate Endpoint (SUR): Serum sodium
Study 12724125 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 24553695 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 18215589 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 1856305 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31214178 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31214178 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 31214178 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 31214178 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 15116254 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7977327 — Surrogate Endpoint (SUR): Blood pressure
Study 818818 — Predictive Biomarker (PRD): GMCL2 mRNA
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 21644312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21644312 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21644312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18840368 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18840368 — Surrogate Endpoint (SUR): Blood pressure
Study 15741556 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 12939564 — Surrogate Endpoint (SUR): Blood pressure
Study 1531095 — Surrogate Endpoint (SUR): Serum creatinine
Study 6238116 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 6238116 — Surrogate Endpoint (SUR): Serum testosterone
Study 30860000 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 30860000 — Predictive Biomarker (PRD): CYBC1 mRNA
Genes: CYBC1; C17orf62; EROS
Study 11917239 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11917239 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25707477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9783800 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 29630101 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31692152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26059332 — Predictive Biomarker (PRD): GNAQ mRNA
Genes: GNAQ; GAQ
Study 26059332 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 23493728 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23493728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23493728 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 23493728 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 16699660 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 11770869 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 26865496 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 26865496 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16513681 — Predictive Biomarker (PRD): XPAC mRNA
Genes: XPA; XPAC
Study 30857410 — Surrogate Endpoint (SUR): Blood pressure
Study 29435996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29435996 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20415698 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 20415698 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9931532 — Surrogate Endpoint (SUR): Bone mineral density
Study 7772643 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26183257 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 20569998 — Surrogate Endpoint (SUR): Blood pressure
Study 20569998 — Surrogate Endpoint (SUR): Serum creatinine
Study 20569998 — Surrogate Endpoint (SUR): Serum uric acid
Study 31236810 — Surrogate Endpoint (SUR): Blood pressure
Study 21292059 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 9573545 — Surrogate Endpoint (SUR): Blood pressure
Study 29499675 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 21604926 — Predictive Biomarker (PRD): FANCI mRNA
Genes: FANCI; KIAA1794
Study 29589138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 29589138 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 29589138 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 29589138 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 29589138 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 28516793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15889524 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28933798 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 24989721 — Safety Biomarker (SAF): Reactive oxygen species
Study 23772021 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 15513323 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15513323 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 15513323 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15513323 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15513323 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11216925 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31297965 — Surrogate Endpoint (SUR): Blood pressure
Study 28550977 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28550977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22382875 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8694309 — Surrogate Endpoint (SUR): Blood pressure
Study 28066111 — Surrogate Endpoint (SUR): Blood pressure
Study 30183338 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 30183338 — Safety Biomarker (SAF): Reactive oxygen species
Study 24739445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24739445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24739445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24739445 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17712763 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9807603 — Surrogate Endpoint (SUR): Blood pressure
Study 28352657 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28352657 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 17602732 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9338882 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 3775141 — Surrogate Endpoint (SUR): Blood pressure
Study 14557435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10389531 — Surrogate Endpoint (SUR): Blood pressure
Study 6407812 — Surrogate Endpoint (SUR): Blood pressure
Study 28558697 — Surrogate Endpoint (SUR): Serum sodium
Study 22153707 — Safety Biomarker (SAF): Hyaluronic acid
Study 20980359 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20980359 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 20980359 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 20980359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1298620 — Surrogate Endpoint (SUR): Serum calcium
Study 29351658 — Surrogate Endpoint (SUR): Blood pressure
Study 23116881 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11775412 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11775412 — Surrogate Endpoint (SUR): Blood pressure
Study 1581948 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20842406 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 16095449 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16095449 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 16095449 — Surrogate Endpoint (SUR): Blood pressure
Study 10089261 — Surrogate Endpoint (SUR): Blood pressure
Study 10089261 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28679686 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21112655 — Monitoring Biomarker (MOI): HBV DNA
Study 8147091 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 18437130 — Surrogate Endpoint (SUR): Blood pressure
Study 16169315 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 10593636 — Surrogate Endpoint (SUR): Blood pressure
Study 9431482 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20136458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20136458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11504166 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3597168 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 25539779 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7967359 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 3602281 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30701750 — Surrogate Endpoint (SUR): Blood pressure
Study 23040595 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 21969495 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 10987607 — Surrogate Endpoint (SUR): Blood pressure
Study 8617895 — Surrogate Endpoint (SUR): Blood pressure
Study 1333903 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 15675184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 28962635 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 18693158 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 16725264 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16725264 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 22906847 — Surrogate Endpoint (SUR): Blood pressure