TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12959311 — Surrogate Endpoint (SUR): Blood pressure
Study 30777123 — Predictive Biomarker (PRD): ZFP57 mRNA
Genes: ZFP57; C6orf40; ZNF698
Study 16538542 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10920469 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 6692287 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 20191783 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 7077546 — Surrogate Endpoint (SUR): Blood pressure
Study 23585423 — Surrogate Endpoint (SUR): Blood pressure
Study 23519055 — Predictive Biomarker (PRD): TYRP1 mRNA
Genes: TYRP1; CAS2; TYRP; TYRRP
Study 23519055 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 10687880 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10687880 — Surrogate Endpoint (SUR): Bone mineral density
Study 30257802 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24676373 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 1345141 — Surrogate Endpoint (SUR): Blood pressure
Study 26511599 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2548552 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30883882 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30883882 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28086917 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 28086917 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MMP10 mRNA
Genes: MMP10; STMY2
Study 22826530 — Surrogate Endpoint (SUR): Blood pressure
Study 17611320 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 16076946 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16076946 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15614703 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 31055568 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 28291972 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 17171863 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11361230 — Surrogate Endpoint (SUR): Blood pressure
Study 27367436 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 18628485 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10190655 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2502385 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30763730 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30763730 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30763730 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 28419124 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26123068 — Predictive Biomarker (PRD): DCLRE1C mRNA
Genes: DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C
Study 17712202 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 14739127 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14739127 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11434163 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26756859 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 11171786 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11171786 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9416986 — Surrogate Endpoint (SUR): Blood pressure
Study 9416986 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3089433 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25972532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25972532 — Surrogate Endpoint (SUR): Blood pressure
Study 27141627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27141627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24168956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19957513 — Surrogate Endpoint (SUR): Serum uric acid
Study 30500603 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20370474 — Surrogate Endpoint (SUR): Blood pressure
Study 17645592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17645592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17645592 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16030154 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8605328 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31688392 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 27261988 — Surrogate Endpoint (SUR): Blood pressure
Study 6414253 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6414253 — Surrogate Endpoint (SUR): Blood pressure
Study 29097388 — Predictive Biomarker (PRD): ALDH1A2 mRNA
Genes: ALDH1A2; RALDH2
Study 29097388 — Predictive Biomarker (PRD): AQP9 mRNA
Genes: AQP9; SSC1
Study 29097388 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 24560012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11606014 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27539273 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 12851517 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12851517 — Surrogate Endpoint (SUR): Bone mineral density
Study 12851517 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12851517 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10541926 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8672412 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29079458 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29079458 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 10669911 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23212700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 23212700 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 23212700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23212700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15266029 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 18071720 — Surrogate Endpoint (SUR): Pathological complete response
Study 30039453 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 22728692 — Monitoring Biomarker (MOI): HBV DNA
Study 9509204 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23390829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12468608 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 10202827 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27438378 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15519660 — Monitoring Biomarker (MOI): HBV DNA
Study 31327701 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 31327701 — Surrogate Endpoint (SUR): Blood pressure
Study 16179044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25070172 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 25070172 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25070172 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25070172 — Predictive Biomarker (PRD): Hormone receptor
Study 22190533 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 12846752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10714731 — Surrogate Endpoint (SUR): Bone mineral density
Study 7587700 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 23325450 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23325450 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23325450 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23325450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23325450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19190344 — Predictive Biomarker (PRD): TTPA mRNA
Genes: TTPA; TPP1
Study 19190344 — Predictive Biomarker (PRD): SEC14L2 mRNA
Genes: SEC14L2; C22orf6; KIAA1186; KIAA1658
Study 12969098 — Predictive Biomarker (PRD): ARX mRNA
Genes: ARX
Study 29246363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21149931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9605674 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7908864 — Surrogate Endpoint (SUR): Serum potassium
Study 10878692 — Surrogate Endpoint (SUR): Blood pressure
Study 10878692 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10878692 — Surrogate Endpoint (SUR): Serum potassium
Study 19175893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28963591 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 12756602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12756602 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10566921 — Surrogate Endpoint (SUR): Blood pressure
Study 1845926 — Surrogate Endpoint (SUR): Serum potassium
Study 31828274 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25138171 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17295721 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10803937 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3533562 — Surrogate Endpoint (SUR): Blood pressure
Study 31255349 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 27720066 — Surrogate Endpoint (SUR): Blood pressure
Study 20185740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20185740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6751705 — Surrogate Endpoint (SUR): Serum creatinine
Study 6751705 — Surrogate Endpoint (SUR): Blood pressure
Study 28328713 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 23057323 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17698897 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 12361192 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12361192 — Surrogate Endpoint (SUR): Blood pressure
Study 6995617 — Surrogate Endpoint (SUR): Blood pressure
Study 23646470 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17844693 — Surrogate Endpoint (SUR): Serum creatinine
Study 18195316 — Surrogate Endpoint (SUR): Blood pressure
Study 12440177 — Surrogate Endpoint (SUR): Serum creatinine
Study 28625806 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 25875387 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 14517708 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11063909 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28832630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28832630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28832630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28832630 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28832630 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28832630 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25879343 — Surrogate Endpoint (SUR): Pathological complete response
Study 23290547 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21088675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21088675 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 21088675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21088675 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 19720764 — Surrogate Endpoint (SUR): Blood pressure
Study 11161394 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9788689 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 31900997 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17006839 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9085509 — Surrogate Endpoint (SUR): Blood pressure
Study 1676891 — Surrogate Endpoint (SUR): Blood pressure
Study 10682152 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1888046 — Surrogate Endpoint (SUR): Blood pressure
Study 30236042 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 18834244 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8912502 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 7705006 — Surrogate Endpoint (SUR): Blood pressure
Study 26031901 — Predictive Biomarker (PRD): GLT1D1 mRNA
Genes: GLT1D1
Study 20217115 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 20217115 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 20217115 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 18387391 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18387391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7840730 — Surrogate Endpoint (SUR): Blood pressure
Study 28249084 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 23746666 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11473855 — Surrogate Endpoint (SUR): Blood pressure
Study 19596188 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18333866 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 23564205 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12047397 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 12047397 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 31728681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31728681 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 18565968 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18565968 — Surrogate Endpoint (SUR): Blood pressure
Study 18565968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1590574 — Surrogate Endpoint (SUR): Blood pressure
Study 19628211 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 12740676 — Safety Biomarker (SAF): Hyaluronic acid
Study 16129365 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 8778905 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26011816 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26011816 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26011816 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 22260834 — Monitoring Biomarker (MOI): HBV DNA
Study 10468801 — Surrogate Endpoint (SUR): Serum creatinine
Study 10468801 — Surrogate Endpoint (SUR): Blood pressure
Study 30359763 — Surrogate Endpoint (SUR): Bone mineral density
Study 23958473 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21030684 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 1761364 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27153942 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 15886446 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15886446 — Surrogate Endpoint (SUR): Blood pressure
Study 416763 — Surrogate Endpoint (SUR): Serum calcium
Study 22035131 — Surrogate Endpoint (SUR): Blood pressure
Study 17956153 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17956153 — Surrogate Endpoint (SUR): Blood pressure
Study 10350494 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 7851558 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 29653550 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28199752 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 28199752 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28199752 — Surrogate Endpoint (SUR): Blood pressure
Study 26233509 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26233509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26233509 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15323062 — Surrogate Endpoint (SUR): Blood pressure
Study 27528062 — Surrogate Endpoint (SUR): Blood pressure
Study 25483635 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15795438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12846271 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 12846271 — Surrogate Endpoint (SUR): Bone mineral density
Study 10975887 — Surrogate Endpoint (SUR): Blood pressure
Study 3915317 — Surrogate Endpoint (SUR): Blood pressure
Study 17898990 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 11567990 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7880511 — Surrogate Endpoint (SUR): Blood pressure
Study 28586262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23262750 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 16196417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16196417 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16196417 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9542208 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 326593 — Surrogate Endpoint (SUR): Blood pressure
Study 10099655 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31557380 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 29519921 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 26346638 — Surrogate Endpoint (SUR): Blood pressure
Study 24940656 — Predictive Biomarker (PRD): ZMYM2 mRNA
Genes: ZMYM2; FIM; RAMP; ZNF198
Study 12389594 — Safety Biomarker (SAF): IL-6 and IL-10
Study 9649908 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 9649908 — Surrogate Endpoint (SUR): Blood pressure
Study 26783978 — Safety Biomarker (SAF): Hyaluronic acid
Study 17928803 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11304505 — Surrogate Endpoint (SUR): Serum creatinine
Study 11304505 — Surrogate Endpoint (SUR): Serum uric acid
Study 9282547 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 8512659 — Surrogate Endpoint (SUR): Blood pressure
Study 3805544 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31053954 — Surrogate Endpoint (SUR): Total kidney volume
Study 31053954 — Surrogate Endpoint (SUR): Serum sodium
Study 31053954 — Surrogate Endpoint (SUR): Serum creatinine
Study 24510471 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 21261107 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11243072 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30382270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18227370 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18227370 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24801367 — Predictive Biomarker (PRD): TMPRSS6 mRNA
Genes: TMPRSS6; UNQ354/PRO618
Study 7494611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7494611 — Safety Biomarker (SAF): Interleukin 1
Study 552657 — Surrogate Endpoint (SUR): Blood pressure
Study 27591988 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 27591988 — Pharmacodynamic Biomarker (PDY): Cytokine ML-1
Genes: IL17F
Study 15983290 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12270981 — Surrogate Endpoint (SUR): Blood pressure
Study 12270981 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 10097934 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10097934 — Surrogate Endpoint (SUR): Blood pressure
Study 8947977 — Surrogate Endpoint (SUR): Blood pressure
Study 31615021 — Surrogate Endpoint (SUR): Blood pressure