TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00922584 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00922584 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01555593 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01555593 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01555593 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01555593 — Safety Biomarker (SAF): Interleukin 1
Study NCT01555593 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study NCT01555593 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01555593 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT04955535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00243399 — Surrogate Endpoint (SUR): Hematologic response
Study NCT03347604 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT03347604 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00806286 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT00845819 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03601364 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03144583 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00289536 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00289536 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT04216563 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04216563 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03509272 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03173638 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04460898 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04460898 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04460898 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04460898 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02695121 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04190537 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01149603 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00150891 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00150891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00150891 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00275938 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02140723 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02140723 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02416024 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03122106 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02733926 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT00920517 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00004363 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT00796263 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01197755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00416884 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02015559 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02015559 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04142892 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04142892 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01340326 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02263781 — Predictive Biomarker (PRD): PREPL mRNA
Genes: PREPL; KIAA0436
Study NCT03666559 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT03666559 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT03666559 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study NCT01971970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01971970 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT03551496 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00003920 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study NCT03180489 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03180489 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02748772 — Predictive Biomarker (PRD): ACRC mRNA
Genes: GCNA; ACRC
Study NCT01861288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01861288 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT03719482 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT00067080 — Predictive Biomarker (PRD): Liver iron
Study NCT02367482 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study NCT03796182 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study NCT01492283 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03220061 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00660205 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03647592 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01894035 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00886288 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00460967 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT01922583 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01922583 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01922583 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01922583 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT01922583 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT00740883 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00361127 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04015713 — Safety Biomarker (SAF): Interleukin 1
Study NCT02249312 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study NCT03789721 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT01512888 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02955381 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03770624 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01161082 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04696198 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02892565 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT00002846 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03448978 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03652558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01865240 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00340717 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT03373552 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03373552 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT03373552 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT03373552 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT03373552 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT03373552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT03373552 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study NCT03373552 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03373552 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study NCT03373552 — Predictive Biomarker (PRD): ITGB3 mRNA
Genes: ITGB3; GP3A
Study NCT03373552 — Predictive Biomarker (PRD): P2RY12 mRNA
Genes: P2RY12; HORK3
Study NCT02620644 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT04041349 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02973230 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02973230 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01968954 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02064751 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03362112 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT04251689 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05671016 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01961843 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00207675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03740412 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03740412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01267721 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT02392351 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00485563 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study NCT01951248 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02318186 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01166165 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04621669 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT04621669 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT04621669 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study NCT04301908 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT04301908 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02789397 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00980525 — Safety Biomarker (SAF): Interleukin 1
Study NCT03429517 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03429517 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04105426 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04838548 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01011985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01011985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02682095 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03696030 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03131492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03131492 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03811717 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study NCT03811717 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT03811717 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study NCT01126411 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00692510 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02790177 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01665300 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00622544 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04732910 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04732910 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study NCT02368951 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT02368951 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT00965939 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05806619 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00103610 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01764529 — Predictive Biomarker (PRD): KRIT1 mRNA
Genes: KRIT1; CCM1
Study NCT01764529 — Predictive Biomarker (PRD): CCM2 mRNA
Genes: CCM2; C7orf22; PP10187
Study NCT01764529 — Predictive Biomarker (PRD): PDCD10 mRNA
Genes: PDCD10; CCM3; TFAR15
Study NCT05835739 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00796133 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study NCT03293134 — Predictive Biomarker (PRD): FLVCR2 mRNA
Genes: FLVCR2; C14orf58
Study NCT03337165 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03520816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05841927 — Predictive Biomarker (PRD): SHANK3 mRNA
Genes: SHANK3; KIAA1650; PROSAP2; PSAP2
Study NCT05841927 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study NCT02384135 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04663113 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04051112 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT01973751 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study NCT04885153 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04885153 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02992418 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02178501 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT02473003 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study NCT03579927 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03579927 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT03579927 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study NCT01704794 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01945671 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01945671 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04779515 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01491555 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00001474 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00001474 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03401359 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03401359 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01154816 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT00961064 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT00961064 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT05178251 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03580083 — Predictive Biomarker (PRD): IDUA mRNA
Genes: IDUA
Study NCT04324541 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT05663736 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02451332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00505232 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01286506 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00511342 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02432040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04692948 — Predictive Biomarker (PRD): CD276 mRNA
Genes: CD276; B7H3; PSEC0249; UNQ309/PRO352
Study NCT04380974 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00503880 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00943982 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02078427 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT03052218 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT05300386 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03097601 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03097601 — Predictive Biomarker (PRD): CSF1 mRNA
Genes: CSF1
Study NCT03097601 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT03097601 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT03097601 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT03097601 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study NCT03394937 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01989962 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01793519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04342468 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04400318 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00186888 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00105300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01877746 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study NCT00004180 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT04304729 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02588222 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study NCT02195089 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00707382 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01630967 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT02816099 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT00642746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00001176 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01196325 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01196325 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01868893 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02338193 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02338193 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02305953 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02305953 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study NCT02305953 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT02171351 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study NCT01715298 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00388999 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT02885181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02422589 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02422589 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02422589 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00859690 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT00489242 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT03470168 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT00835926 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study NCT00950963 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04405843 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00340223 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study NCT03038399 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01700582 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01700582 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study NCT01700582 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01700582 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01700582 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02606812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02606812 — Safety Biomarker (SAF): miR-320