TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25295500 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25301151 — Predictive Biomarker (PRD): IDE mRNA
Genes: IDE
Study 25301367 — Predictive Biomarker (PRD): FCGR2B
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study 25301708 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25301783 — Surrogate Endpoint (SUR): Serum creatinine
Study 25303490 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 25305705 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25305705 — Surrogate Endpoint (SUR): Blood pressure
Study 25306425 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25306425 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 25306425 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 25308138 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25312589 — Surrogate Endpoint (SUR): Bone mineral density
Study 25313095 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 25313914 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 25314291 — Predictive Biomarker (PRD): CD300LG mRNA
Genes: CD300LG; CLM9; TREM4; UNQ422/PRO846
Study 25314291 — Surrogate Endpoint (SUR): Blood pressure
Study 25315258 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25316810 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 25317870 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25317870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25318437 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25319501 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25319501 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 25320355 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 25323230 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 25323764 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 25324042 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25324042 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25324042 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 25324042 — Surrogate Endpoint (SUR): Blood pressure
Study 25326543 — Surrogate Endpoint (SUR): Blood pressure
Study 25328681 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25328681 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25328681 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25329038 — Surrogate Endpoint (SUR): Blood pressure
Study 25329562 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 25330000 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25330000 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 25330000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25330984 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 25331113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25331113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25331535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25331535 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25332322 — Surrogate Endpoint (SUR): Blood pressure
Study 25336464 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25336464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25336940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25338318 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 25338318 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25340778 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25340778 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25341798 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25341798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25341798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25341798 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25342141 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25344522 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25345578 — Surrogate Endpoint (SUR): Blood pressure
Study 25345697 — Predictive Biomarker (PRD): Liver iron
Study 25348520 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 25348609 — Predictive Biomarker (PRD): SLC30A8 mRNA
Genes: SLC30A8; ZNT8
Study 25349073 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25349960 — Surrogate Endpoint (SUR): Bone mineral density
Study 25349968 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 25349968 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25349968 — Surrogate Endpoint (SUR): Blood pressure
Study 25353072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25353072 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25355590 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 25355716 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 25355844 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25357043 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25357043 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 25358868 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25358868 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 25358868 — Predictive Biomarker (PRD): SPATS2L mRNA
Genes: SPATS2L; DNAPTP6; SP1224
Study 25358868 — Safety Biomarker (SAF): BDNF
Study 25359432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25359988 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 25359994 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 25359994 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 25359994 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 25360888 — Predictive Biomarker (PRD): PEAR1 mRNA
Genes: PEAR1; MEGF12
Study 25361837 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 25361837 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 25363329 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25363329 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25363329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25368957 — Monitoring Biomarker (MOI): HBV DNA
Study 25370510 — Predictive Biomarker (PRD): GMCL2 mRNA
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 25370513 — Predictive Biomarker (PRD): GMCL2 mRNA
Genes: GMCL2; GCL; GMCL1L; GMCL1P1
Study 25371447 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 25371817 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 25373117 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 25374386 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25375983 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25376399 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25376618 — Predictive Biomarker (PRD): SSTR5 mRNA
Genes: SSTR5
Study 25378645 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25380582 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 25380654 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25380748 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 25381092 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 25385099 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25385103 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 25385345 — Predictive Biomarker (PRD): ATP2B1 mRNA
Genes: ATP2B1; PMCA1
Study 25385409 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25385439 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 25385439 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25385737 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25387261 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 25387261 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 25387993 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25388167 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study 25392649 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 25393536 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25393640 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 25393648 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25394029 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25394040 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 25394040 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 25394054 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25394093 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25394116 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25394537 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 25394537 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 25394537 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 25394537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25395187 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25395260 — Monitoring Biomarker (MOI): HBV DNA
Study 25395425 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25395429 — Predictive Biomarker (PRD): CDK5 mRNA
Genes: CDK5; CDKN5; PSSALRE
Study 25396060 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25396065 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 25397516 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25397516 — Surrogate Endpoint (SUR): Serum creatinine
Study 25397527 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25401382 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 25402221 — Surrogate Endpoint (SUR): Serum creatinine
Study 25403217 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25404952 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 25404952 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 25405275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25405351 — Predictive Biomarker (PRD): TNFSF14 mRNA
Genes: TNFSF14; HVEML; LIGHT; UNQ391/PRO726
Study 25405497 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 25405497 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 25405500 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 25405619 — Surrogate Endpoint (SUR): Blood pressure
Study 25405619 — Surrogate Endpoint (SUR): Serum creatinine
Study 25405724 — Predictive Biomarker (PRD): TMPRSS13 mRNA
Genes: TMPRSS13; MSP; TMPRSS11
Study 25407698 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 25408112 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 25408147 — Predictive Biomarker (PRD): SFRP4 mRNA
Genes: SFRP4; FRPHE
Study 25411038 — Predictive Biomarker (PRD): HDGFL2 mRNA
Genes: HDGFL2; HDGF2; HDGFRP2; HRP2; UNQ785/PRO1604
Study 25411038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25411281 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 25411281 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 25411281 — Predictive Biomarker (PRD): COL22A1 mRNA
Genes: COL22A1
Study 25411281 — Predictive Biomarker (PRD): CDO1 mRNA
Genes: CDO1
Study 25411281 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 25412225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25413133 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25415228 — Predictive Biomarker (PRD): MCTS1 mRNA
Genes: MCTS1; MCT1
Study 25416807 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 25416807 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 25416807 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 25421091 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 25423261 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25424529 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25424783 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25425230 — Surrogate Endpoint (SUR): Blood pressure
Study 25427282 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 25427282 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 25427282 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25427282 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25428504 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 25428504 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 25428504 — Predictive Biomarker (PRD): NELFCD mRNA
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 25428504 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 25428504 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 25428650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25428714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25428714 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25430934 — Pharmacodynamic Biomarker (PDY): Peripheral myelin protein 22
Genes: PMP22; GAS3
Study 25430934 — Predictive Biomarker (PRD): GJB1 mRNA
Genes: GJB1; CX32
Study 25430934 — Predictive Biomarker (PRD): MPZ mRNA
Genes: MPZ
Study 25432492 — Safety Biomarker (SAF): MTHFR
Study 25432492 — Surrogate Endpoint (SUR): Blood pressure
Study 25432592 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 25435886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25436806 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 25438151 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25439094 — Surrogate Endpoint (SUR): Blood pressure
Study 25439094 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25441108 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 25441108 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 25441679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25441726 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 25441734 — Surrogate Endpoint (SUR): Bone mineral density
Study 25441735 — Monitoring Biomarker (MOI): Procalcitonin
Study 25441735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25441924 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 25442084 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 25442074 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 25444147 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 25444527 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 25444527 — Predictive Biomarker (PRD): ABCG8 mRNA
Genes: ABCG8
Study 25444722 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 25444722 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 25444722 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 25444781 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 25444781 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25444781 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 25444781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25447728 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25449569 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 25450031 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 25450031 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25450151 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 25451051 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 25452198 — Surrogate Endpoint (SUR): Blood pressure
Study 25452867 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25452867 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25453890 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 25453890 — Surrogate Endpoint (SUR): Blood pressure
Study 25456362 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25456368 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25456368 — Surrogate Endpoint (SUR): Pathological complete response
Study 25457633 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study 25457633 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 25459109 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25459109 — Surrogate Endpoint (SUR): Serum creatinine
Study 25460357 — Predictive Biomarker (PRD): TNC mRNA
Genes: TNC; HXB
Study 25460357 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 25461821 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 25461821 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 25461821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25461821 — Safety Biomarker (SAF): IL16
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 25461821 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 25464386 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 25464386 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 25466382 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25466382 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25466513 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25466778 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 25470338 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25470338 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25472823 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25472874 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25473804 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25473804 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25474185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25474373 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25475068 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25478017 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25479121 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 25480498 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25481712 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25481820 — Surrogate Endpoint (SUR): Blood pressure
Study 25482239 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 25482239 — Predictive Biomarker (PRD): PDCD1LG2 mRNA
Genes: PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2
Study 25482239 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 25486412 — Predictive Biomarker (PRD): DNAJB1 mRNA
Genes: DNAJB1; DNAJ1; HDJ1; HSPF1
Study 25486412 — Predictive Biomarker (PRD): PRKACA mRNA
Genes: PRKACA; PKACA
Study 25488930 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1