TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27535783 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 27535783 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 24958563 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 22678051 — Surrogate Endpoint (SUR): Blood pressure
Study 11319711 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 22540417 — Surrogate Endpoint (SUR): Sperm parameters
Study 4911774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31709970 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19276838 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11485076 — Monitoring Biomarker (MOI): HBV DNA
Study 6108780 — Surrogate Endpoint (SUR): Blood pressure
Study 28343975 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26430724 — Predictive Biomarker (PRD): INPP5F mRNA
Genes: INPP5F; KIAA0966; SAC2; MSTP007; MSTP047
Study 26430724 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 16102623 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 16102623 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16102623 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1462277 — Surrogate Endpoint (SUR): Blood pressure
Study 15723869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15723869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9866433 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17156591 — Surrogate Endpoint (SUR): Serum creatinine
Study 29168427 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29168427 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24729102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24729102 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21106264 — Surrogate Endpoint (SUR): Serum creatinine
Study 15768050 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 12465429 — Surrogate Endpoint (SUR): Serum creatinine
Study 29380013 — Surrogate Endpoint (SUR): Bone mineral density
Study 23435876 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 18458207 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 14990264 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9052890 — Surrogate Endpoint (SUR): Serum creatinine
Study 9052890 — Surrogate Endpoint (SUR): Blood pressure
Study 7639352 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 23010608 — Surrogate Endpoint (SUR): Blood pressure
Study 21781652 — Surrogate Endpoint (SUR): Blood pressure
Study 15961217 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 30113633 — Surrogate Endpoint (SUR): Blood pressure
Study 22648836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22648836 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 14564334 — Surrogate Endpoint (SUR): Blood pressure
Study 10981255 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 8888380 — Surrogate Endpoint (SUR): Blood pressure
Study 24509027 — Surrogate Endpoint (SUR): Blood pressure
Study 11131271 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11131271 — Safety Biomarker (SAF): Urinary microalbumin
Study 11131271 — Surrogate Endpoint (SUR): Serum creatinine
Study 11131271 — Surrogate Endpoint (SUR): Blood pressure
Study 1433739 — Surrogate Endpoint (SUR): Blood pressure
Study 25223172 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 17679728 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17679728 — Predictive Biomarker (PRD): Hormone receptor
Study 29045529 — Predictive Biomarker (PRD): MKNK1 mRNA
Genes: MKNK1; MNK1
Study 15310780 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7945617 — Surrogate Endpoint (SUR): Blood pressure
Study 25537011 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25537011 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 12826500 — Surrogate Endpoint (SUR): Serum creatinine
Study 28629243 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27232378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 27232378 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 12656935 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12656935 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 12656935 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 12656935 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8739020 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8739020 — Surrogate Endpoint (SUR): Blood pressure
Study 22257685 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22257685 — Surrogate Endpoint (SUR): Serum creatinine
Study 22257685 — Surrogate Endpoint (SUR): Blood pressure
Study 22257685 — Surrogate Endpoint (SUR): Serum potassium
Study 21743374 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11400186 — Surrogate Endpoint (SUR): Blood pressure
Study 24944136 — Surrogate Endpoint (SUR): Bone mineral density
Study 12882850 — Surrogate Endpoint (SUR): Blood pressure
Study 10995003 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10995003 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 10995003 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8630632 — Surrogate Endpoint (SUR): Serum creatinine
Study 24752311 — Predictive Biomarker (PRD): PAX4 mRNA
Genes: PAX4
Study 21741883 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 6144241 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31738483 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18632258 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28626140 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 17140552 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17140552 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17140552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6103680 — Surrogate Endpoint (SUR): Blood pressure
Study 27751654 — Surrogate Endpoint (SUR): Blood pressure
Study 21135204 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study 17369118 — Surrogate Endpoint (SUR): Serum creatinine
Study 8775569 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 20507375 — Surrogate Endpoint (SUR): Probing pocket depth
Study 1736694 — Surrogate Endpoint (SUR): Blood pressure
Study 31085043 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31085043 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29698651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29698651 — Surrogate Endpoint (SUR): Sperm parameters
Study 12134102 — Surrogate Endpoint (SUR): Blood pressure
Study 30705097 — Surrogate Endpoint (SUR): Serum asparaginase
Study 15957997 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 2149053 — Surrogate Endpoint (SUR): Serum creatinine
Study 20535518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20535518 — Surrogate Endpoint (SUR): Probing pocket depth
Study 14990637 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27187047 — Surrogate Endpoint (SUR): Blood pressure
Study 19583677 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29691148 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21952034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21211387 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22982353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19383221 — Surrogate Endpoint (SUR): Blood pressure
Study 17461960 — Safety Biomarker (SAF): Hyaluronic acid
Study 31422486 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31422486 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15240411 — Surrogate Endpoint (SUR): Blood pressure
Study 9678107 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8471132 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 29503145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19087716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17112304 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17112304 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8862940 — Surrogate Endpoint (SUR): Blood pressure
Study 8862940 — Surrogate Endpoint (SUR): Serum potassium
Study 1736500 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25212457 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 16142596 — Surrogate Endpoint (SUR): Blood pressure
Study 26573431 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26573431 — Safety Biomarker (SAF): BDNF
Study 3300457 — Surrogate Endpoint (SUR): Blood pressure
Study 31597523 — Predictive Biomarker (PRD): HIPK3 mRNA
Genes: HIPK3; DYRK6; FIST3; PKY
Study 31597523 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31597523 — Predictive Biomarker (PRD): FOXM1 mRNA
Genes: FOXM1; FKHL16; HFH11; MPP2; WIN
Study 19182178 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 17483968 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 8043974 — Surrogate Endpoint (SUR): Serum creatinine
Study 8043974 — Surrogate Endpoint (SUR): Blood pressure
Study 3052785 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 25522265 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 15015440 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 7870965 — Surrogate Endpoint (SUR): Blood pressure
Study 24887018 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 21211458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21211458 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29496255 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29496255 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 22997204 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30135888 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22220807 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study 22295891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20554982 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8885957 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8885957 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28929919 — Surrogate Endpoint (SUR): Bone mineral density
Study 30037301 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 30388751 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 19996066 — Surrogate Endpoint (SUR): Blood pressure
Study 29231349 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12966367 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12966367 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10852440 — Surrogate Endpoint (SUR): Bone mineral density
Study 2895577 — Surrogate Endpoint (SUR): Blood pressure
Study 19448566 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11884296 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31587091 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31623857 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21836102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21836102 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10090926 — Surrogate Endpoint (SUR): Hematologic response
Study 2084727 — Surrogate Endpoint (SUR): Blood pressure
Study 26519 — Surrogate Endpoint (SUR): Blood pressure
Study 12084021 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 20357176 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16136044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16136044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16136044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1951878 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 20141248 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 15849806 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 15849806 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 15849806 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 15849806 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 12227681 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 12227681 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 12227681 — Surrogate Endpoint (SUR): Blood pressure
Study 3881561 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22898251 — Surrogate Endpoint (SUR): Blood pressure
Study 22898251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22898251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3315592 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22503139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22503139 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22503139 — Safety Biomarker (SAF): Interleukin 1
Study 22503139 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9419782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9419782 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23132848 — Surrogate Endpoint (SUR): Blood pressure
Study 19118825 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 19118825 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 16728231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15226097 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30840633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30840633 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 30840633 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30840633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26000301 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 18842671 — Surrogate Endpoint (SUR): Blood pressure
Study 21788625 — Surrogate Endpoint (SUR): Blood pressure
Study 9194208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27369111 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11961610 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7646913 — Surrogate Endpoint (SUR): Serum testosterone
Study 28829792 — Predictive Biomarker (PRD): IKBKB mRNA
Genes: IKBKB; IKKB
Study 28829792 — Predictive Biomarker (PRD): AK4 mRNA
Genes: AK4; AK3; AK3L1
Study 11833048 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11833048 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 11833048 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 11833048 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11833048 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23415431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23415431 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23415431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23415431 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21240901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26143444 — Monitoring Biomarker (MOI): HBV DNA
Study 17361529 — Surrogate Endpoint (SUR): Blood pressure
Study 8671551 — Surrogate Endpoint (SUR): Serum triglycerides
Study 1817621 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 22137075 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 29926695 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 29926695 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24530676 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22228743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15685250 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15685250 — Surrogate Endpoint (SUR): Blood pressure
Study 15685250 — Predictive Biomarker (PRD): NE
Study 9097708 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12728539 — Surrogate Endpoint (SUR): Blood pressure
Study 1414040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2580179 — Surrogate Endpoint (SUR): Blood pressure
Study 30569654 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 10453872 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 498720 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 498720 — Surrogate Endpoint (SUR): Blood pressure
Study 24121064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24121064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24121064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24121064 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2676257 — Surrogate Endpoint (SUR): Blood pressure
Study 25770117 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25770117 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17576863 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1110481 — Surrogate Endpoint (SUR): Blood pressure
Study 1110481 — Surrogate Endpoint (SUR): Serum sodium
Study 16019766 — Surrogate Endpoint (SUR): Blood pressure
Study 26209166 — Surrogate Endpoint (SUR): Bone mineral density
Study 22237871 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9470169 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21774822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12568942 — Surrogate Endpoint (SUR): Blood pressure
Study 10563276 — Surrogate Endpoint (SUR): Blood pressure
Study 30848023 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30848023 — Surrogate Endpoint (SUR): Blood pressure
Study 17067837 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 3341527 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16283318 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 16283318 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 102114 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29874805 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 24390777 — Surrogate Endpoint (SUR): Bone mineral density
Study 15924805 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8703644 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8703644 — Surrogate Endpoint (SUR): Blood pressure
Study 31691462 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31691462 — Surrogate Endpoint (SUR): Platelet count response
Study 28181131 — Surrogate Endpoint (SUR): Blood pressure
Study 12113380 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17335405 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 17335405 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 3284943 — Surrogate Endpoint (SUR): Blood pressure