TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18303125 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 25841237 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 18073318 — Surrogate Endpoint (SUR): Blood pressure
Study 18929400 — Predictive Biomarker (PRD): RRH mRNA
Genes: RRH
Study 16444853 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31778115 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27371291 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9625132 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30954341 — Surrogate Endpoint (SUR): Blood pressure
Study 28502543 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 10188768 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10188768 — Safety Biomarker (SAF): Reactive oxygen species
Study 10188768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7493146 — Surrogate Endpoint (SUR): Blood pressure
Study 22387567 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19145426 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8052457 — Surrogate Endpoint (SUR): Bone mineral density
Study 1696670 — Surrogate Endpoint (SUR): Blood pressure
Study 18807218 — Surrogate Endpoint (SUR): Blood pressure
Study 15548718 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7946944 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15165407 — Surrogate Endpoint (SUR): Blood pressure
Study 15165407 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25892145 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24165884 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 11768727 — Surrogate Endpoint (SUR): Blood pressure
Study 16600745 — Surrogate Endpoint (SUR): Blood pressure
Study 9315415 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22297398 — Surrogate Endpoint (SUR): Bone mineral density
Study 15976341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15976341 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28329080 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28329080 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 23646475 — Monitoring Biomarker (MOI): Procalcitonin
Study 23646475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23646475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23646475 — Safety Biomarker (SAF): IL-6 and IL-10
Study 3414546 — Surrogate Endpoint (SUR): Blood pressure
Study 28523945 — Surrogate Endpoint (SUR): Bone mineral density
Study 25757964 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 24311403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24311403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24311403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16861093 — Surrogate Endpoint (SUR): Blood pressure
Study 9756109 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 27967328 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 27967328 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 23978392 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 9350661 — Surrogate Endpoint (SUR): Blood pressure
Study 7537921 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29972310 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29972310 — Surrogate Endpoint (SUR): Blood pressure
Study 22832068 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 6981173 — Surrogate Endpoint (SUR): Serum creatinine
Study 17322149 — Surrogate Endpoint (SUR): Serum creatinine
Study 9688487 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 2783352 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25577145 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 25577145 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 17467513 — Surrogate Endpoint (SUR): Blood pressure
Study 2892582 — Surrogate Endpoint (SUR): Blood pressure
Study 24394704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24394704 — Surrogate Endpoint (SUR): Blood pressure
Study 24394704 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22426371 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18536785 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16640103 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31123801 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20833738 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 20833738 — Surrogate Endpoint (SUR): Serum creatinine
Study 20833738 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16338269 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11889016 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22042958 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15161788 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 11549098 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25240692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8274414 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8274414 — Surrogate Endpoint (SUR): Serum testosterone
Study 3011048 — Surrogate Endpoint (SUR): Blood pressure
Study 16877482 — Surrogate Endpoint (SUR): Serum creatinine
Study 16877482 — Surrogate Endpoint (SUR): Blood pressure
Study 30108162 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30108162 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19512875 — Surrogate Endpoint (SUR): Blood pressure
Study 17445178 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 14514942 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 14514942 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 26577998 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25247319 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8701508 — Surrogate Endpoint (SUR): Blood pressure
Study 23866471 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23866471 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 23866471 — Surrogate Endpoint (SUR): Serum creatinine
Study 16138974 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16138974 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12012289 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8903665 — Surrogate Endpoint (SUR): Blood pressure
Study 8903665 — Surrogate Endpoint (SUR): Serum potassium
Study 18728056 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 18728056 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19786145 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19786145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21393114 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21393114 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14642699 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 14642699 — Surrogate Endpoint (SUR): Blood pressure
Study 31111250 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28985434 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 26573509 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29342248 — Predictive Biomarker (PRD): Hormone receptor
Study 27677387 — Surrogate Endpoint (SUR): Blood pressure
Study 22282478 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20104189 — Surrogate Endpoint (SUR): Blood pressure
Study 14961168 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12458652 — Surrogate Endpoint (SUR): Blood pressure
Study 9657564 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9657564 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 9657564 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9657564 — Safety Biomarker (SAF): Human leucocyte antigen
Study 9657564 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 21679485 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 12488121 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 12488121 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30119694 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 25183511 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 2038782 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 26667921 — Surrogate Endpoint (SUR): Blood pressure
Study 10759236 — Monitoring Biomarker (MOI): HBV DNA
Study 29406176 — Surrogate Endpoint (SUR): Blood pressure
Study 15992652 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12637120 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1319111 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3897044 — Surrogate Endpoint (SUR): Blood pressure
Study 20403471 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12354174 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12354174 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 12354174 — Safety Biomarker (SAF): Human leucocyte antigen
Study 12354174 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10965249 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28399620 — Safety Biomarker (SAF): Reactive oxygen species
Study 23921615 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 23921615 — Surrogate Endpoint (SUR): Bone mineral density
Study 9382123 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8282350 — Surrogate Endpoint (SUR): Blood pressure
Study 8282350 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30274540 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 26087670 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21098626 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23046599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23046599 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23046599 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20730514 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19430807 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12482564 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27994711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27994711 — Monitoring Biomarker (MOI): Procalcitonin
Study 27994711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27994711 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 27994711 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27994711 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20543740 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 20543740 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 18626566 — Surrogate Endpoint (SUR): Bone mineral density
Study 11561568 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2142580 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 6197010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26872608 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17951477 — Surrogate Endpoint (SUR): Blood pressure
Study 2669667 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2669667 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2996575 — Surrogate Endpoint (SUR): Blood pressure
Study 2996575 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20410232 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 8365381 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24907689 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 24907689 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22549281 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22549281 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16153933 — Surrogate Endpoint (SUR): Blood pressure
Study 15207898 — Surrogate Endpoint (SUR): Bone mineral density
Study 9141148 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21814218 — Surrogate Endpoint (SUR): Blood pressure
Study 28432326 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28432326 — Predictive Biomarker (PRD): APOBEC3G mRNA
Genes: APOBEC3G; MDS019
Study 28432326 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 21323294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15656396 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 18180897 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11171827 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 30962268 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30962268 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 27770397 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21569343 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 2939219 — Surrogate Endpoint (SUR): Blood pressure
Study 30027406 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30027406 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 30027406 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 26883089 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 26883089 — Predictive Biomarker (PRD): TRPA1 mRNA
Genes: TRPA1; ANKTM1
Study 26883089 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 17432675 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 30484837 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21143244 — Surrogate Endpoint (SUR): Blood pressure
Study 18212696 — Surrogate Endpoint (SUR): Serum creatinine
Study 17021320 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 17021320 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8549570 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1777370 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 9014648 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 24146070 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22683131 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9130895 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 29301558 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25143169 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25143169 — Surrogate Endpoint (SUR): Blood pressure
Study 20656748 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8610621 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29755474 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 29755474 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 18259011 — Surrogate Endpoint (SUR): Blood pressure
Study 16701922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2580172 — Surrogate Endpoint (SUR): Blood pressure
Study 2580172 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25398084 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24321171 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 2434759 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2434759 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 25715786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17962512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17962512 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12852708 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12852708 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10377209 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 21471566 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19494025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19494025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19494025 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16424644 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28394302 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28394302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28394302 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25224665 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8435991 — Surrogate Endpoint (SUR): Blood pressure
Study 26555944 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 26555944 — Surrogate Endpoint (SUR): Serum creatinine
Study 1959800 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 19337788 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19337788 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 19337788 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 19337788 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17473847 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 17473847 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17473847 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 15717138 — Surrogate Endpoint (SUR): Blood pressure
Study 11443170 — Surrogate Endpoint (SUR): Bone mineral density
Study 28720147 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19239555 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15329509 — Surrogate Endpoint (SUR): Blood pressure
Study 9283055 — Surrogate Endpoint (SUR): Blood pressure
Study 9283055 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28088925 — Predictive Biomarker (PRD): KY mRNA
Genes: KY
Study 23650800 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21091250 — Surrogate Endpoint (SUR): Blood pressure
Study 18209670 — Safety Biomarker (SAF): Reactive oxygen species
Study 12595499 — Surrogate Endpoint (SUR): Serum creatinine
Study 7512469 — Surrogate Endpoint (SUR): Blood pressure
Study 7512469 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29568976 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 27879642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27879642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27879642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20735515 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15851525 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31553517 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 31553517 — Surrogate Endpoint (SUR): Blood pressure
Study 24014349 — Surrogate Endpoint (SUR): Blood pressure
Study 1527232 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 30952505 — Surrogate Endpoint (SUR): Blood pressure
Study 30952505 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22301554 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 22301554 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 22301554 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC