TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27547421 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 17595249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24798861 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 24798861 — Surrogate Endpoint (SUR): Blood pressure
Study 23054692 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19541737 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12584829 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12584829 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25791145 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 25791145 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 25791145 — Surrogate Endpoint (SUR): Blood pressure
Study 23397566 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21808398 — Surrogate Endpoint (SUR): Blood pressure
Study 11529281 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7877584 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 19861516 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 19861516 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 16611155 — Safety Biomarker (SAF): Reactive oxygen species
Study 11733267 — Predictive Biomarker (PRD): PEBP1 mRNA
Genes: PEBP1; PBP; PEBP
Study 7898090 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7898090 — Surrogate Endpoint (SUR): Blood pressure
Study 19318984 — Surrogate Endpoint (SUR): Blood pressure
Study 11431729 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 19309347 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 16679086 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16679086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16679086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29121431 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22519736 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20447617 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7595729 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2151889 — Surrogate Endpoint (SUR): Blood pressure
Study 28370357 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 21718471 — Predictive Biomarker (PRD): IKZF2 mRNA
Genes: IKZF2; HELIOS; ZNFN1A2
Study 21718471 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19092694 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12775279 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7380205 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27347034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 22413874 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17995698 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31654487 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 23413101 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 23413101 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17268414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11793034 — Surrogate Endpoint (SUR): Blood pressure
Study 18268396 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 18268396 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18268396 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18268396 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 18268396 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18268396 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17133610 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 17133610 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8857479 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8857479 — Surrogate Endpoint (SUR): Blood pressure
Study 31919749 — Monitoring Biomarker (MOI): HBV DNA
Study 23522322 — Predictive Biomarker (PRD): IL18RAP mRNA
Genes: IL18RAP; IL1R7
Study 23522322 — Predictive Biomarker (PRD): IL18R1 mRNA
Genes: IL18R1; IL1RRP
Study 23522322 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 23522322 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 21644315 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21644315 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20108857 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 29940980 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26468947 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26468947 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17159974 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 16868345 — Surrogate Endpoint (SUR): Blood pressure
Study 14521274 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 2871492 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27876084 — Monitoring Biomarker (MOI): Cell-free DNA
Study 16117979 — Surrogate Endpoint (SUR): Blood pressure
Study 16117979 — Surrogate Endpoint (SUR): Serum uric acid
Study 8567109 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1427129 — Surrogate Endpoint (SUR): Blood pressure
Study 24840638 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 23094708 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20823434 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17680841 — Surrogate Endpoint (SUR): Blood pressure
Study 16273650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11812714 — Surrogate Endpoint (SUR): Blood pressure
Study 16368447 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 16368447 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16368447 — Safety Biomarker (SAF): Reactive oxygen species
Study 16368447 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16368447 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9463746 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8590792 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8590792 — Surrogate Endpoint (SUR): Blood pressure
Study 31866533 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 26181538 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 16750670 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7968593 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7968593 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 7968593 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7968593 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7968593 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7968593 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20798226 — Surrogate Endpoint (SUR): Blood pressure
Study 8498367 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25034548 — Predictive Biomarker (PRD): CPTP mRNA
Genes: CPTP; GLTPD1
Study 20032570 — Surrogate Endpoint (SUR): Blood pressure
Study 20032570 — Surrogate Endpoint (SUR): Serum creatinine
Study 7839377 — Surrogate Endpoint (SUR): Blood pressure
Study 30301829 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28367891 — Surrogate Endpoint (SUR): Probing pocket depth
Study 9610348 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9610348 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31711707 — Surrogate Endpoint (SUR): Serum testosterone
Study 31711707 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24249434 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27040576 — Surrogate Endpoint (SUR): Serum uric acid
Study 20844462 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 14504183 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25607608 — Surrogate Endpoint (SUR): Bone mineral density
Study 23340810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16461847 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11684280 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 22837190 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22837190 — Surrogate Endpoint (SUR): Blood pressure
Study 22837190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18227326 — Predictive Biomarker (PRD): SERPINA2 mRNA
Genes: SERPINA2; ARGS; ATR; PIL; SERPINA2P
Study 16186374 — Surrogate Endpoint (SUR): Blood pressure
Study 8902152 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 20538134 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20538134 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17933700 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29903591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20953062 — Surrogate Endpoint (SUR): Blood pressure
Study 26486256 — Surrogate Endpoint (SUR): Blood pressure
Study 23939663 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 15065831 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15065831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15065831 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 30666834 — Predictive Biomarker (PRD): Microsatellite instability
Study 7859140 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7859140 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 30042516 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 30042516 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30042516 — Predictive Biomarker (PRD): ODC1 mRNA
Genes: ODC1
Study 17157479 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 31021123 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24396060 — Surrogate Endpoint (SUR): Blood pressure
Study 27189595 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21968546 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 21968546 — Predictive Biomarker (PRD): TET1 mRNA
Genes: TET1; CXXC6; KIAA1676; LCX
Study 21968546 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 15727386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15727386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15727386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15727386 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12548530 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 10588224 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25149894 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25149894 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22573845 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27537387 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 9757196 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 1467634 — Surrogate Endpoint (SUR): Blood pressure
Study 30450642 — Surrogate Endpoint (SUR): Blood pressure
Study 9812659 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28165812 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 18272842 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 7000296 — Surrogate Endpoint (SUR): Blood pressure
Study 28379536 — Surrogate Endpoint (SUR): Total kidney volume
Study 24618326 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 30569216 — Surrogate Endpoint (SUR): Bone mineral density
Study 28333288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28333288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9856966 — Surrogate Endpoint (SUR): Blood pressure
Study 6089950 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30028519 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 12569384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 12569384 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12569384 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 19958076 — Surrogate Endpoint (SUR): Blood pressure
Study 17503172 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21626296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8986932 — Surrogate Endpoint (SUR): Blood pressure
Study 8986932 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29862877 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 28457847 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19506195 — Surrogate Endpoint (SUR): Blood pressure
Study 15671911 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 368852 — Surrogate Endpoint (SUR): Blood pressure
Study 25813765 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9660430 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 30369370 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30369370 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19539385 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 11834878 — Surrogate Endpoint (SUR): Serum potassium
Study 10428996 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30948567 — Surrogate Endpoint (SUR): Blood pressure
Study 25650503 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15259323 — Predictive Biomarker (PRD): SPDEF mRNA
Genes: SPDEF; PDEF; PSE
Study 8320931 — Surrogate Endpoint (SUR): Blood pressure
Study 31473291 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28819782 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 28819782 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 23848219 — Surrogate Endpoint (SUR): Blood pressure
Study 23848219 — Surrogate Endpoint (SUR): Serum uric acid
Study 23027887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15856430 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 11919725 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 11252079 — Surrogate Endpoint (SUR): Blood pressure
Study 25008392 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 22825089 — Surrogate Endpoint (SUR): Blood pressure
Study 20032964 — Surrogate Endpoint (SUR): Serum creatinine
Study 12868185 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 27756583 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21482968 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 19071236 — Surrogate Endpoint (SUR): Bone mineral density
Study 412613 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 23449826 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23449826 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 22066891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22066891 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22066891 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22066891 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16141462 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 3950827 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 10749463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8932983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21768463 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 21768463 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21768463 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19755462 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19755462 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 19755462 — Surrogate Endpoint (SUR): Serum creatinine
Study 19755462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15310009 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 9154286 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 9154286 — Surrogate Endpoint (SUR): Blood pressure
Study 9154286 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29243965 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 29243965 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 29243965 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study 25405014 — Predictive Biomarker (PRD): MAP9 mRNA
Genes: MAP9; ASAP
Study 15223865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15223865 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15223865 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15223865 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8318241 — Surrogate Endpoint (SUR): Blood pressure
Study 31972249 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study 31972249 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 31972249 — Predictive Biomarker (PRD): KRT16 mRNA
Genes: KRT16; KRT16A
Study 31972249 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 31972249 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 30907230 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 27390168 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 19597879 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11339485 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28281738 — Surrogate Endpoint (SUR): Serum creatinine
Study 23483064 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18981044 — Surrogate Endpoint (SUR): Blood pressure
Study 10939175 — Predictive Biomarker (PRD): SCGB1A1 mRNA
Genes: SCGB1A1; CC10; CCSP; UGB
Study 20215710 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19469273 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 1319109 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31525580 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21146673 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 3101502 — Safety Biomarker (SAF): Hyaluronic acid
Study 21257787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21257787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2439800 — Surrogate Endpoint (SUR): Blood pressure
Study 23301468 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23301468 — Safety Biomarker (SAF): BDNF
Study 9163278 — Surrogate Endpoint (SUR): Blood pressure
Study 18640991 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2138973 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2138973 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27688475 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 27688475 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19254211 — Surrogate Endpoint (SUR): Serum creatinine
Study 16442924 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 16442924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15630287 — Surrogate Endpoint (SUR): Bone mineral density
Study 15630287 — Surrogate Endpoint (SUR): Blood pressure
Study 2667859 — Surrogate Endpoint (SUR): Blood pressure
Study 23855681 — Predictive Biomarker (PRD): SH3PXD2A mRNA
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study 11737512 — Surrogate Endpoint (SUR): Probing pocket depth
Study 9227247 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 12959311 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12959311 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR