TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29446098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22519866 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8600628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8440768 — Surrogate Endpoint (SUR): Blood pressure
Study 25635327 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21708185 — Surrogate Endpoint (SUR): Blood pressure
Study 16424784 — Surrogate Endpoint (SUR): Blood pressure
Study 25231677 — Surrogate Endpoint (SUR): Bone mineral density
Study 23652739 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16433771 — Surrogate Endpoint (SUR): Serum creatinine
Study 3222154 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31698359 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 31698359 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 31698359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28275830 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 14523272 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10801756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 24241212 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30887731 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25524798 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 25524798 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 25524798 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 11251037 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 29599478 — Surrogate Endpoint (SUR): Blood pressure
Study 19939723 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11836044 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study 7538237 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 1632402 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17949394 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 25920709 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 25146067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17464093 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 3289433 — Monitoring Biomarker (MOI): HBV DNA
Study 31084985 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study 31084985 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 31084985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31084985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28284500 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18160344 — Surrogate Endpoint (SUR): Blood pressure
Study 8688986 — Surrogate Endpoint (SUR): Blood pressure
Study 31196169 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28639119 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28639119 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 28639119 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 9709409 — Surrogate Endpoint (SUR): Blood pressure
Study 2736920 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 15228134 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 11494442 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23839107 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21172891 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 2495813 — Surrogate Endpoint (SUR): Blood pressure
Study 27005817 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 12439737 — Surrogate Endpoint (SUR): Blood pressure
Study 8557961 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8557961 — Surrogate Endpoint (SUR): Blood pressure
Study 19300110 — Surrogate Endpoint (SUR): Blood pressure
Study 19300110 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2439821 — Surrogate Endpoint (SUR): Blood pressure
Study 24394187 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18222355 — Predictive Biomarker (PRD): KIF6 mRNA
Genes: KIF6; C6orf102
Study 18222355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18222355 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11587165 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11587165 — Surrogate Endpoint (SUR): Blood pressure
Study 9396419 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22262230 — Surrogate Endpoint (SUR): Serum creatinine
Study 16138795 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 11856154 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11856154 — Predictive Biomarker (PRD): Hormone receptor
Study 25037695 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25037695 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21605716 — Surrogate Endpoint (SUR): Bone mineral density
Study 24887336 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15151839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15151839 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11831545 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23169801 — Surrogate Endpoint (SUR): Blood pressure
Study 19709689 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19709689 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7700062 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 4921284 — Surrogate Endpoint (SUR): Blood pressure
Study 27899357 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 8574175 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 31882586 — Predictive Biomarker (PRD): Hormone receptor
Study 16953261 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11465642 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11465642 — Surrogate Endpoint (SUR): Blood pressure
Study 27287832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27287832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24331381 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24331381 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15017671 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 11200367 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28256104 — Surrogate Endpoint (SUR): Blood pressure
Study 22511592 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 19935373 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 16796694 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15273706 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29778750 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18955835 — Surrogate Endpoint (SUR): Serum creatinine
Study 18955835 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16551862 — Surrogate Endpoint (SUR): Blood pressure
Study 8706298 — Surrogate Endpoint (SUR): Bone mineral density
Study 28063503 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 23810688 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23810688 — Surrogate Endpoint (SUR): Serum creatinine
Study 19291931 — Surrogate Endpoint (SUR): Bone mineral density
Study 8198981 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28494895 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28494895 — Surrogate Endpoint (SUR): Blood pressure
Study 30663788 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 30663788 — Surrogate Endpoint (SUR): Probing pocket depth
Study 30663788 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30663788 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28373523 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31207908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17095943 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22234084 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8835618 — Surrogate Endpoint (SUR): Blood pressure
Study 30038044 — Monitoring Biomarker (MOI): HBV DNA
Study 18469239 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26284393 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11265777 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11265777 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 24954607 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 15911729 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15911729 — Surrogate Endpoint (SUR): Blood pressure
Study 10475418 — Safety Biomarker (SAF): Urinary microalbumin
Study 20647390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31820546 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12955284 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 2653119 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2653119 — Surrogate Endpoint (SUR): Blood pressure
Study 902556 — Surrogate Endpoint (SUR): Blood pressure
Study 20964739 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 19017883 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17380844 — Surrogate Endpoint (SUR): Blood pressure
Study 1902298 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29727016 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 29727016 — Predictive Biomarker (PRD): TFAM mRNA
Genes: TFAM; TCF6; TCF6L2
Study 29727016 — Predictive Biomarker (PRD): DNM1L mRNA
Genes: DNM1L; DLP1; DRP1
Study 29727016 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 29727016 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 26018112 — Predictive Biomarker (PRD): Liver iron
Study 18437288 — Surrogate Endpoint (SUR): Blood pressure
Study 9176650 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29090473 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 18387054 — Monitoring Biomarker (MOI): HBV DNA
Study 14673431 — Safety Biomarker (SAF): Hyaluronic acid
Study 10545428 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26946057 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 15789316 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22926161 — Predictive Biomarker (PRD): MTRR mRNA
Genes: MTRR
Study 22926161 — Safety Biomarker (SAF): MTHFR
Study 15615740 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 9828903 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9828903 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9828903 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 9828903 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9828903 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30761459 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29530884 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29530884 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29530884 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22337760 — Surrogate Endpoint (SUR): Blood pressure
Study 22337760 — Surrogate Endpoint (SUR): Serum creatinine
Study 8596484 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10051804 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31529104 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 18278078 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11828038 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 28408798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16600583 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 10766183 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10766183 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 10766183 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10766183 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 1864787 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22805286 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15345867 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11393673 — Surrogate Endpoint (SUR): Blood pressure
Study 31219052 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23359066 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 23359066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16198451 — Predictive Biomarker (PRD): FCGR2A
Genes: CD32; CD32A; IGFR2; CDw32; Fc-gamma-RIIa; FcgammaRIIa
Study 26621483 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 24929235 — Monitoring Biomarker (MOI): HBV DNA
Study 20137789 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11949767 — Safety Biomarker (SAF): DRD2
Study 11949767 — Surrogate Endpoint (SUR): Blood pressure
Study 10505032 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16923922 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16923922 — Surrogate Endpoint (SUR): Blood pressure
Study 28744796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27053384 — Surrogate Endpoint (SUR): Blood pressure
Study 22085840 — Surrogate Endpoint (SUR): Bone mineral density
Study 20079899 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28770449 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 13678775 — Surrogate Endpoint (SUR): Bone mineral density
Study 10916115 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10023788 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 2224121 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 31277052 — Surrogate Endpoint (SUR): Blood pressure
Study 21332722 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 21332722 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 17519315 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24958282 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24958282 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 24958282 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 24958282 — Predictive Biomarker (PRD): MDM4 mRNA
Genes: MDM4; MDMX
Study 24958282 — Predictive Biomarker (PRD): TP53BP1 mRNA
Genes: TP53BP1
Study 24958282 — Predictive Biomarker (PRD): ADH1C mRNA
Genes: ADH1C; ADH3
Study 30216917 — Predictive Biomarker (PRD): CACNA1C mRNA
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 26935057 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26935057 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 18333864 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10412882 — Surrogate Endpoint (SUR): Blood pressure
Study 31641967 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31538180 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31538180 — Surrogate Endpoint (SUR): Blood pressure
Study 21976257 — Surrogate Endpoint (SUR): Blood pressure
Study 29961816 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 20420761 — Predictive Biomarker (PRD): SLC2A2 mRNA
Genes: SLC2A2; GLUT2
Study 16942867 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16259175 — Surrogate Endpoint (SUR): Bone mineral density
Study 31365109 — Surrogate Endpoint (SUR): Blood pressure
Study 25774975 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25774975 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 19734256 — Surrogate Endpoint (SUR): Blood pressure
Study 17143194 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 17143194 — Surrogate Endpoint (SUR): Blood pressure
Study 9743401 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30897995 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18029171 — Surrogate Endpoint (SUR): Bone mineral density
Study 1348403 — Surrogate Endpoint (SUR): Blood pressure
Study 3994353 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27435894 — Surrogate Endpoint (SUR): Blood pressure
Study 14969833 — Monitoring Biomarker (MOI): HBV DNA
Study 22623396 — Surrogate Endpoint (SUR): Serum calcium
Study 31521337 — Surrogate Endpoint (SUR): Serum creatinine
Study 21056606 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21056606 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26206095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23642949 — Surrogate Endpoint (SUR): Blood pressure
Study 9055905 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 2409278 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2409278 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23574148 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23574148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11917051 — Surrogate Endpoint (SUR): Blood pressure
Study 11917051 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11917051 — Surrogate Endpoint (SUR): Serum creatinine
Study 11917051 — Surrogate Endpoint (SUR): Serum potassium
Study 25960284 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 25960284 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 25960284 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25960284 — Safety Biomarker (SAF): Reactive oxygen species
Study 9337183 — Surrogate Endpoint (SUR): Serum potassium
Study 20979460 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31780332 — Surrogate Endpoint (SUR): Blood pressure
Study 23835715 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19382089 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31692553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31692553 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25117183 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25117183 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 25117183 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 25117183 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25117183 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17479946 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 820357 — Surrogate Endpoint (SUR): Blood pressure
Study 30591415 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23475405 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 17725739 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9514183 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9514183 — Surrogate Endpoint (SUR): Blood pressure
Study 9050476 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30137242 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 25494323 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 19469115 — Surrogate Endpoint (SUR): Blood pressure
Study 10472854 — Surrogate Endpoint (SUR): Bone mineral density
Study 8752759 — Surrogate Endpoint (SUR): Blood pressure
Study 12447551 — Surrogate Endpoint (SUR): Blood pressure
Study 1968731 — Surrogate Endpoint (SUR): Blood pressure
Study 1968731 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22221684 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 16426267 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 16426267 — Safety Biomarker (SAF): BDNF
Study 31699568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31699568 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27459721 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25497995 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9625847 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9625847 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 2686259 — Surrogate Endpoint (SUR): Blood pressure
Study 19317378 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 2544345 — Surrogate Endpoint (SUR): Blood pressure
Study 29179134 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29179134 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25894531 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 25894531 — Predictive Biomarker (PRD): SCNN1A mRNA
Genes: SCNN1A; SCNN1
Study 17824291 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9645829 — Surrogate Endpoint (SUR): Serum creatinine
Study 9645829 — Surrogate Endpoint (SUR): Blood pressure
Study 15998708 — Surrogate Endpoint (SUR): Blood pressure
Study 12023684 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5