TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00991666 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02984189 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT02984189 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00569296 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00569296 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02626364 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT02141282 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02211573 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01718847 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04900831 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study NCT00842686 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00760877 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT01388608 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02637700 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study NCT00002733 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02063490 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT00712829 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT02069509 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT00511615 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00511615 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT02492620 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02492620 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03928847 — Predictive Biomarker (PRD): LOXL2 mRNA
Genes: LOXL2
Study NCT04284592 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT04881851 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT04881851 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01881230 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03678532 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00652236 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT04268433 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00849407 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study NCT01474044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04265274 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04265274 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02397421 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT01057420 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT01057420 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00590447 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03806959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01589445 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study NCT01466023 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT01466023 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02351063 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02284711 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02617511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02617511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02617511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03501758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03371992 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03371992 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02192255 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02003131 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00415233 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02083731 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01661192 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00674453 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01471106 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02571972 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02571972 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01337219 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01092182 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT01092182 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01831154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04568980 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04568980 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study NCT04568980 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study NCT00701441 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00322842 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03947255 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT03560531 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03560531 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03560531 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02496455 — Predictive Biomarker (PRD): SCN9A mRNA
Genes: SCN9A; NENA
Study NCT04495127 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT02304263 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04571710 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03527199 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04197414 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03975907 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT01631058 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT01631058 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00939913 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT00911677 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT05048810 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT05373420 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01477060 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01477060 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT01477060 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study NCT01477060 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01932229 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01932229 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01907555 — Predictive Biomarker (PRD): VPS13B mRNA
Genes: VPS13B; CHS1; COH1; KIAA0532
Study NCT01852942 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00691535 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00691535 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT00691535 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study NCT00654173 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01227772 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT03669692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00660582 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00660582 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03054857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03054857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02479087 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02910219 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03679910 — Predictive Biomarker (PRD): CEMIP mRNA
Genes: CEMIP; KIAA1199
Study NCT03679910 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03318315 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02109120 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT00441844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01086540 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03164928 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT03164928 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01295515 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02133950 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT05028439 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT01454570 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05511883 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT05511883 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT04390477 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05880927 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03720496 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00003147 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT04184531 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study NCT04184531 — Predictive Biomarker (PRD): WDR19 mRNA
Genes: WDR19; IFT144; KIAA1638
Study NCT04184531 — Predictive Biomarker (PRD): WDR35 mRNA
Genes: WDR35; IFT121; KIAA1336
Study NCT01317745 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01007045 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01476696 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01153243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01153243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04337983 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00353912 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01617915 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT01617915 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01741181 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02377752 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT03274531 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04135833 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT02340598 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04225299 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT03297385 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT03065244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01285245 — Safety Biomarker (SAF): Interleukin 1
Study NCT00556608 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02031198 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03380000 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02691481 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02691481 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02691481 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT04581070 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01117025 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02391974 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02391974 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00457756 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT01674985 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01793714 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT03723330 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00207012 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00672295 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT00672295 — Predictive Biomarker (PRD): CRK mRNA
Genes: CRK
Study NCT04353375 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study NCT04353375 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT06211452 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT06211452 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study NCT06211452 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYH11 mRNA
Genes: MYH11; KIAA0866
Study NCT06211452 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02379403 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03391076 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02451488 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02451488 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT00328887 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT01797315 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study NCT01425749 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03731546 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03379259 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03067844 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03067844 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03156855 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01078870 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study NCT01227109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04401904 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04401904 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT04401904 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01498458 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01498458 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01498458 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01498458 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study NCT01498458 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01400516 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03226340 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00422903 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02023450 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT02023450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02023450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04382469 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03470311 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT03186261 — Surrogate Endpoint (SUR): Bacterial count
Study NCT03581682 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00431496 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01450696 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02786147 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01930851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04571775 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study NCT04898257 — Safety Biomarker (SAF): 51Cr-EDTA
Study NCT01655979 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03325738 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03325738 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00462761 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT04599374 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04599374 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04599374 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT01697423 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02393833 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02393833 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study NCT02393833 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02393833 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02341807 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study NCT03061812 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study NCT02959047 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT02959047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02959047 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00119392 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02448238 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02448238 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT02448238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02448238 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01791842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01962129 — Predictive Biomarker (PRD): OFD1 mRNA
Genes: OFD1; CXorf5
Study NCT01559896 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01559896 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03897400 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02879409 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT04681924 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT04681924 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04681924 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02258126 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02004028 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT02773927 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02773927 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00284479 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00885755 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04467879 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01378299 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study NCT00101114 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT00100243 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00629499 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01393808 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00908726 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study NCT02078154 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01271920 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00791518 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03071458 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03618485 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study NCT03618485 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study NCT03618485 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT03618485 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT03841734 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT04163861 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT03638115 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01225172 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04244513 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT02271581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01324388 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00597623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2