TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30474740 — Surrogate Endpoint (SUR): Bone mineral density
Study 30474740 — Surrogate Endpoint (SUR): Blood pressure
Study 29937430 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 29937430 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27085076 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 27085076 — Surrogate Endpoint (SUR): Blood pressure
Study 22128082 — Surrogate Endpoint (SUR): Serum creatinine
Study 31773485 — Predictive Biomarker (PRD): SLC39A13 mRNA
Genes: SLC39A13; ZIP13
Study 31773485 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29157592 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23537980 — Surrogate Endpoint (SUR): Blood pressure
Study 15848534 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 27965111 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study 11325074 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11325074 — Surrogate Endpoint (SUR): Serum creatinine
Study 11325074 — Surrogate Endpoint (SUR): Blood pressure
Study 7956637 — Surrogate Endpoint (SUR): Blood pressure
Study 28737251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24022862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23757053 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 20733306 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19053918 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 7772012 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7772012 — Surrogate Endpoint (SUR): Bone mineral density
Study 27989018 — Safety Biomarker (SAF): Hyaluronic acid
Study 16679098 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8822354 — Surrogate Endpoint (SUR): Bone mineral density
Study 22853865 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20164809 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 30699446 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 1959887 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 26934084 — Safety Biomarker (SAF): MTHFR
Study 26934084 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17495205 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 14630619 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29703576 — Predictive Biomarker (PRD): HRC mRNA
Genes: HRC; HCP
Study 21186071 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 18316562 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18316562 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16179584 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16179584 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 26486166 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26486166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23628600 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 17174223 — Predictive Biomarker (PRD): PLA2G7 mRNA
Genes: PLA2G7; PAFAH
Study 15095048 — Surrogate Endpoint (SUR): Blood pressure
Study 3262857 — Safety Biomarker (SAF): Preexisting antibody
Study 28712786 — Surrogate Endpoint (SUR): Serum testosterone
Study 21633086 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 16245263 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3108527 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3108527 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29189215 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 16282544 — Surrogate Endpoint (SUR): Blood pressure
Study 25175981 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8061851 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8061851 — Surrogate Endpoint (SUR): Blood pressure
Study 3058238 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23590301 — Predictive Biomarker (PRD): FOXP1 mRNA
Genes: FOXP1; HSPC215
Study 23590301 — Predictive Biomarker (PRD): TCF7 mRNA
Genes: TCF7; TCF1
Study 23590301 — Predictive Biomarker (PRD): ASAH1 mRNA
Genes: ASAH1; ASAH; HSD-33; HSD33
Study 20459731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20459731 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19808428 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19808428 — Surrogate Endpoint (SUR): Blood pressure
Study 16650165 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 16650165 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12118963 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 23470116 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 20357375 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20357375 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20357375 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20357375 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 3555355 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15929961 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31371432 — Surrogate Endpoint (SUR): Blood pressure
Study 31371432 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21418260 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9526933 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31619654 — Surrogate Endpoint (SUR): Bone mineral density
Study 25894894 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 23562359 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15220018 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15220018 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15220018 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26264550 — Surrogate Endpoint (SUR): Blood pressure
Study 19245687 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 27184046 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 11904107 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8706195 — Surrogate Endpoint (SUR): Blood pressure
Study 30829137 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 30829137 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 30829137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29986492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29986492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26908432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25559753 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 25559753 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 19138241 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31475493 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31475493 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 31475493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31475493 — Safety Biomarker (SAF): BDNF
Study 28682897 — Predictive Biomarker (PRD): ARHGEF5 mRNA
Genes: ARHGEF5; TIM
Study 28682897 — Predictive Biomarker (PRD): EDAR mRNA
Genes: EDAR; DL
Study 10878624 — Predictive Biomarker (PRD): PURA mRNA
Genes: PURA; PUR1
Study 3534590 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8561065 — Surrogate Endpoint (SUR): Blood pressure
Study 8561065 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17465499 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17465499 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 11207001 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29377592 — Safety Biomarker (SAF): miR-133a
Study 29377592 — Safety Biomarker (SAF): miR-16
Study 29377592 — Safety Biomarker (SAF): let-7a
Study 29377592 — Safety Biomarker (SAF): miR-1
Study 29377592 — Predictive Biomarker (PRD): let-7b
Genes: MIRLET7B
Study 11997276 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 8536154 — Surrogate Endpoint (SUR): Blood pressure
Study 28730418 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12461419 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31633520 — Surrogate Endpoint (SUR): Blood pressure
Study 24460645 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22832965 — Safety Biomarker (SAF): DRD2
Study 12145118 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 29442057 — Surrogate Endpoint (SUR): Blood pressure
Study 11914029 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 8123395 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12918543 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 11708573 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30663869 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 30663869 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 27846612 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31895298 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23114833 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 23114833 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 20456839 — Surrogate Endpoint (SUR): Blood pressure
Study 9569951 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 27099232 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15015273 — Predictive Biomarker (PRD): STT3A mRNA
Genes: STT3A; ITM1; TMC
Study 1884876 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 1884876 — Surrogate Endpoint (SUR): Blood pressure
Study 14970281 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7796237 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 26493989 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 20609098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18206407 — Predictive Biomarker (PRD): SRGN mRNA
Genes: SRGN; PRG; PRG1
Study 16339924 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 30266466 — Safety Biomarker (SAF): Hyaluronic acid
Study 17823365 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17823365 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17823365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17823365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8363164 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9638718 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 3057851 — Surrogate Endpoint (SUR): Blood pressure
Study 23370314 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 19548858 — Surrogate Endpoint (SUR): Blood pressure
Study 8247951 — Surrogate Endpoint (SUR): Blood pressure
Study 31329288 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 12519083 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12519083 — Surrogate Endpoint (SUR): Serum sodium
Study 10486683 — Surrogate Endpoint (SUR): Blood pressure
Study 21185738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21185738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7651074 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2668325 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 29527345 — Surrogate Endpoint (SUR): Blood pressure
Study 26799692 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 16926184 — Predictive Biomarker (PRD): ASPRV1 mRNA
Genes: ASPRV1; SASP
Study 9357940 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8453557 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 27920153 — Surrogate Endpoint (SUR): Total kidney volume
Study 19898644 — Surrogate Endpoint (SUR): Blood pressure
Study 17205144 — Surrogate Endpoint (SUR): Blood pressure
Study 9143861 — Surrogate Endpoint (SUR): Blood pressure
Study 9143861 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9143861 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20667993 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 20667993 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 20667993 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 20667993 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 27680990 — Surrogate Endpoint (SUR): Blood pressure
Study 16698259 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29778856 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 8848318 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 8848318 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 27063315 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 15928250 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2126361 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2126361 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 832432 — Surrogate Endpoint (SUR): Blood pressure
Study 29667507 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 29667507 — Predictive Biomarker (PRD): PPP1R12A mRNA
Genes: PPP1R12A; MBS; MYPT1
Study 27323445 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 18984430 — Surrogate Endpoint (SUR): Blood pressure
Study 11918749 — Surrogate Endpoint (SUR): Blood pressure
Study 11918749 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23846810 — Surrogate Endpoint (SUR): Blood pressure
Study 8708510 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17224198 — Surrogate Endpoint (SUR): Blood pressure
Study 2693686 — Surrogate Endpoint (SUR): Blood pressure
Study 323705 — Surrogate Endpoint (SUR): Blood pressure
Study 27919362 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24534599 — Surrogate Endpoint (SUR): Blood pressure
Study 24534599 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24534599 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20868963 — Surrogate Endpoint (SUR): Blood pressure
Study 7662221 — Surrogate Endpoint (SUR): Blood pressure
Study 2527541 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2527541 — Surrogate Endpoint (SUR): Blood pressure
Study 28612547 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 21475137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21475137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21475137 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21475137 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21475137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14998850 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 30442080 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19738135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19738135 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8408529 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 2880597 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27325848 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 20439295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18633045 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2265371 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23357523 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23357523 — Surrogate Endpoint (SUR): Blood pressure
Study 17596103 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17596103 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31180297 — Surrogate Endpoint (SUR): Blood pressure
Study 16681436 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9771317 — Surrogate Endpoint (SUR): Blood pressure
Study 7827234 — Surrogate Endpoint (SUR): Probing pocket depth
Study 3063797 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3063797 — Surrogate Endpoint (SUR): Blood pressure
Study 8201490 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21167330 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 14645173 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study 14645173 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 10594624 — Surrogate Endpoint (SUR): Blood pressure
Study 2363300 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24271 — Surrogate Endpoint (SUR): Blood pressure
Study 12572377 — Surrogate Endpoint (SUR): Blood pressure
Study 12572377 — Surrogate Endpoint (SUR): Serum creatinine
Study 12800417 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12800417 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8872850 — Surrogate Endpoint (SUR): Blood pressure
Study 17347809 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 16123680 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27321790 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21791141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21791141 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 17156836 — Surrogate Endpoint (SUR): Blood pressure
Study 8714736 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30461602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30461602 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18835506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18835506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12034156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12034156 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 329406 — Surrogate Endpoint (SUR): Bone mineral density
Study 29752009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27620862 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 25137844 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7799030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7799030 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7799030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 371643 — Surrogate Endpoint (SUR): Blood pressure
Study 17309996 — Safety Biomarker (SAF): Hyaluronic acid
Study 15115710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9862512 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8541104 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19232887 — Surrogate Endpoint (SUR): Bone mineral density
Study 11950697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11950697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 611325 — Surrogate Endpoint (SUR): Blood pressure
Study 23302544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18808335 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18808335 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31030100 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R