TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21289263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21289263 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 31292752 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31292752 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 24948347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11784224 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11784224 — Surrogate Endpoint (SUR): Blood pressure
Study 30696387 — Surrogate Endpoint (SUR): Blood pressure
Study 29596044 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29596044 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27310969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16103236 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2407889 — Safety Biomarker (SAF): Interleukin 1
Study 30566363 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30566363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30566363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26474430 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23388562 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 11320362 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9230234 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 8121125 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8121125 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25856785 — Surrogate Endpoint (SUR): Blood pressure
Study 11380543 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 11380543 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 8820892 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15812751 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10352369 — Surrogate Endpoint (SUR): Blood pressure
Study 8547856 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8547856 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24179298 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 19745649 — Surrogate Endpoint (SUR): Blood pressure
Study 17078221 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28215130 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study 24357810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24357810 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 17413096 — Surrogate Endpoint (SUR): Blood pressure
Study 15480049 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 11843382 — Surrogate Endpoint (SUR): Bone mineral density
Study 25428209 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25428209 — Surrogate Endpoint (SUR): Blood pressure
Study 17562958 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15486408 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 11712824 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11712824 — Surrogate Endpoint (SUR): Blood pressure
Study 3195433 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23824974 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 18565233 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16497101 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14571257 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 3281463 — Surrogate Endpoint (SUR): Serum creatinine
Study 30083968 — Predictive Biomarker (PRD): CFL1 mRNA
Genes: CFL1; CFL
Study 25431336 — Surrogate Endpoint (SUR): Serum sodium
Study 25431336 — Surrogate Endpoint (SUR): Blood pressure
Study 19921623 — Predictive Biomarker (PRD): CLYBL mRNA
Genes: CLYBL; CLB
Study 10694624 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31096953 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 21219602 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 10088202 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 10088202 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25660012 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study 23374797 — Surrogate Endpoint (SUR): Serum creatinine
Study 28534476 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 21359598 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8218957 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 29931320 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29931320 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8781317 — Predictive Biomarker (PRD): GYPC mRNA
Genes: GYPC; GLPC; GPC
Study 26850805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26850805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25628416 — Surrogate Endpoint (SUR): Blood pressure
Study 25628416 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24124708 — Surrogate Endpoint (SUR): Blood pressure
Study 21905967 — Surrogate Endpoint (SUR): Blood pressure
Study 15454860 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24331152 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 29364754 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 28065217 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23312052 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26762528 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22332671 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 30533392 — Surrogate Endpoint (SUR): Blood pressure
Study 23850055 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 1613201 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 29901704 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 404962 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16224053 — Predictive Biomarker (PRD): CX3CL1 mRNA
Genes: CX3CL1; FKN; NTT; SCYD1; A-152E5.2
Study 16224053 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 16224053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21701406 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 18372036 — Surrogate Endpoint (SUR): Blood pressure
Study 11164440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11164440 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11164440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11164440 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9206670 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3707649 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30081801 — Surrogate Endpoint (SUR): Blood pressure
Study 30081801 — Surrogate Endpoint (SUR): Bone mineral density
Study 26899608 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21070920 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9581666 — Surrogate Endpoint (SUR): Blood pressure
Study 18568960 — Surrogate Endpoint (SUR): Blood pressure
Study 16423096 — Surrogate Endpoint (SUR): Blood pressure
Study 11821634 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11821634 — Surrogate Endpoint (SUR): Blood pressure
Study 29241199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17318022 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 17318022 — Surrogate Endpoint (SUR): Bone mineral density
Study 15203784 — Surrogate Endpoint (SUR): Blood pressure
Study 24050416 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 19912735 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19912735 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 17215115 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29310326 — Surrogate Endpoint (SUR): Blood pressure
Study 19632953 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9430359 — Monitoring Biomarker (MOI): HBV DNA
Study 26178282 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 21733322 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 21733322 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21733322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9166393 — Surrogate Endpoint (SUR): Bone mineral density
Study 9166393 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 20977639 — Surrogate Endpoint (SUR): Blood pressure
Study 15837256 — Surrogate Endpoint (SUR): Blood pressure
Study 11886767 — Surrogate Endpoint (SUR): Bone mineral density
Study 11886767 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11886767 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10334534 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8547939 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2041284 — Surrogate Endpoint (SUR): Blood pressure
Study 30841568 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 30841568 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 30841568 — Predictive Biomarker (PRD): LPCAT1 mRNA
Genes: LPCAT1; AYTL2; PFAAP3
Study 30841568 — Predictive Biomarker (PRD): PLA2G4A mRNA
Genes: PLA2G4A; CPLA2; PLA2G4
Study 30841568 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study 30841568 — Predictive Biomarker (PRD): PTGER3 mRNA
Genes: PTGER3
Study 30841568 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30841568 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 30841568 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 10848851 — Surrogate Endpoint (SUR): Serum creatinine
Study 9116627 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 29743334 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study 29743334 — Safety Biomarker (SAF): 51Cr-EDTA
Study 25241324 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 21474566 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10363856 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1782100 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30626939 — Predictive Biomarker (PRD): DLK1 mRNA
Genes: DLK1; DLK
Study 23313567 — Surrogate Endpoint (SUR): Blood pressure
Study 19301686 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15514264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27712015 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27712015 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 27712015 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27712015 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 27712015 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24891327 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20650046 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18614998 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18614998 — Surrogate Endpoint (SUR): Serum creatinine
Study 8772222 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 8772222 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24098467 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24098467 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19158122 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19158122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19158122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17338996 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17338996 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17338996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17338996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10711861 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10711861 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9248764 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 26429200 — Safety Biomarker (SAF): miR-192
Genes: MIR192
Study 26429200 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study 26429200 — Safety Biomarker (SAF): miR-15a
Genes: MIR15A
Study 26429200 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 20404738 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18779612 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11217593 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 3131470 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21558582 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 19705041 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15042531 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31736069 — Surrogate Endpoint (SUR): Blood pressure
Study 21901256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21901256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21901256 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21901256 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15988404 — Surrogate Endpoint (SUR): Bone mineral density
Study 15988404 — Surrogate Endpoint (SUR): Serum calcium
Study 15988404 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 7698300 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29888580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12974590 — Surrogate Endpoint (SUR): Blood pressure
Study 8677754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8677754 — Safety Biomarker (SAF): Interleukin 1
Study 1577028 — Surrogate Endpoint (SUR): Blood pressure
Study 23537008 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23537008 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23537008 — Safety Biomarker (SAF): IL-6 and IL-10
Study 14515937 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 25794890 — Predictive Biomarker (PRD): Hormone receptor
Study 23018784 — Surrogate Endpoint (SUR): Bone mineral density
Study 16816950 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 1715503 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18356253 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 14656275 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30720582 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 24401089 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18074937 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10648270 — Surrogate Endpoint (SUR): Bone mineral density
Study 22727972 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16995975 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 29798127 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26245802 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 28886907 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 19208729 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19208729 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2839019 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25740979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20176450 — Surrogate Endpoint (SUR): Blood pressure
Study 16545724 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16545724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1389714 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15071488 — Surrogate Endpoint (SUR): Blood pressure
Study 2919758 — Surrogate Endpoint (SUR): Blood pressure
Study 1313120 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 1313120 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10920832 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 9012304 — Surrogate Endpoint (SUR): Blood pressure
Study 25781214 — Surrogate Endpoint (SUR): Serum creatinine
Study 23234408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19228175 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8435972 — Surrogate Endpoint (SUR): Serum creatinine
Study 25079465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31179920 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 28841230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15266173 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7193603 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23333777 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23333777 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21392395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29529387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23866906 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 23866906 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 20593240 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 8779402 — Surrogate Endpoint (SUR): Blood pressure
Study 29601997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16187007 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10459816 — Surrogate Endpoint (SUR): Serum creatinine
Study 7541236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31881421 — Surrogate Endpoint (SUR): Blood pressure
Study 26524046 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2529294 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31924637 — Surrogate Endpoint (SUR): Blood pressure
Study 20413297 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20413297 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11958302 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8790030 — Surrogate Endpoint (SUR): Blood pressure
Study 18520806 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15637747 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12069179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8776071 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 6286734 — Surrogate Endpoint (SUR): Blood pressure
Study 6286734 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2153765 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 22441634 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20423436 — Surrogate Endpoint (SUR): Serum potassium
Study 15954959 — Surrogate Endpoint (SUR): Blood pressure
Study 30299258 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27883295 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 27883295 — Predictive Biomarker (PRD): SLC5A6 mRNA
Genes: SLC5A6; SMVT
Study 27883295 — Predictive Biomarker (PRD): ABCB4 mRNA
Genes: ABCB4; MDR3; PGY3
Study 27883295 — Predictive Biomarker (PRD): ABCC5 mRNA
Genes: ABCC5; MRP5
Study 25125580 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8