TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21234528 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 11831117 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11831117 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8639722 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8639722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30747707 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11920412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31164429 — Surrogate Endpoint (SUR): Blood pressure
Study 20107424 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12126174 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26489022 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 26489022 — Surrogate Endpoint (SUR): Blood pressure
Study 24480677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24480677 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21761705 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 25801872 — Surrogate Endpoint (SUR): Blood pressure
Study 14671251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14671251 — Surrogate Endpoint (SUR): Serum uric acid
Study 14671251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14671251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11704025 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 11704025 — Surrogate Endpoint (SUR): Blood pressure
Study 2467139 — Surrogate Endpoint (SUR): Blood pressure
Study 12472790 — Surrogate Endpoint (SUR): Serum calcium
Study 10716688 — Monitoring Biomarker (MOI): HBV DNA
Study 29512481 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22723310 — Surrogate Endpoint (SUR): Bone mineral density
Study 9730792 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 7518981 — Surrogate Endpoint (SUR): Blood pressure
Study 7518981 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21355157 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11896626 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 11896626 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 11896626 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 90215 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23289548 — Safety Biomarker (SAF): BDNF
Study 14703595 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1832516 — Surrogate Endpoint (SUR): Blood pressure
Study 7046331 — Surrogate Endpoint (SUR): Blood pressure
Study 24315572 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 20142023 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 20142023 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20142023 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 18388356 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2454359 — Surrogate Endpoint (SUR): Blood pressure
Study 17101625 — Surrogate Endpoint (SUR): Bone mineral density
Study 11889149 — Surrogate Endpoint (SUR): Bone mineral density
Study 9462526 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 22374183 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12670837 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 9139272 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 29907211 — Surrogate Endpoint (SUR): Blood pressure
Study 26917157 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 18418433 — Surrogate Endpoint (SUR): Blood pressure
Study 10782623 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 8877661 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31325499 — Surrogate Endpoint (SUR): Blood pressure
Study 31325499 — Surrogate Endpoint (SUR): Serum sodium
Study 25631734 — Surrogate Endpoint (SUR): Blood pressure
Study 1885274 — Surrogate Endpoint (SUR): Blood pressure
Study 11334210 — Surrogate Endpoint (SUR): Serum creatinine
Study 28345814 — Surrogate Endpoint (SUR): Blood pressure
Study 26041602 — Surrogate Endpoint (SUR): Blood pressure
Study 26310670 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 23850610 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31131671 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 31131671 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 31131671 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 31131671 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 31131671 — Surrogate Endpoint (SUR): Blood pressure
Study 11982838 — Surrogate Endpoint (SUR): Blood pressure
Study 28822563 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 21372264 — Surrogate Endpoint (SUR): Blood pressure
Study 30922878 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24641328 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 20118387 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20118387 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7898092 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7898092 — Surrogate Endpoint (SUR): Blood pressure
Study 14615726 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10771453 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30006015 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17711511 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10790350 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 11317490 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8615360 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30616442 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20863994 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 20863994 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20863994 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 15998659 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15998659 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 15998659 — Predictive Biomarker (PRD): TCHH mRNA
Genes: TCHH; THH; THL; TRHY
Study 30934066 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 9345396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9345396 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22263337 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15015442 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22451470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22451470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18828769 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 18828769 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 18828769 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 18828769 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18828769 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 18828769 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 18828769 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16583932 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 22465268 — Surrogate Endpoint (SUR): Bone mineral density
Study 6358654 — Surrogate Endpoint (SUR): Serum creatinine
Study 31930897 — Surrogate Endpoint (SUR): Blood pressure
Study 20012296 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 20012296 — Surrogate Endpoint (SUR): Bacterial count
Study 10365639 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 31913428 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 26689589 — Predictive Biomarker (PRD): APLP1 mRNA
Genes: APLP1
Study 10867091 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9772413 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9772413 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8246027 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31450983 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16995870 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3276185 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3276185 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3276185 — Surrogate Endpoint (SUR): Blood pressure
Study 31372823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31372823 — Surrogate Endpoint (SUR): Blood pressure
Study 26439700 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 14551526 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29433963 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29433963 — Predictive Biomarker (PRD): Hormone receptor
Study 1672967 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6130595 — Surrogate Endpoint (SUR): Blood pressure
Study 19473807 — Surrogate Endpoint (SUR): Bone mineral density
Study 10915751 — Monitoring Biomarker (MOI): HBV DNA
Study 28429577 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24030130 — Surrogate Endpoint (SUR): Blood pressure
Study 21149662 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17461873 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6796322 — Surrogate Endpoint (SUR): Blood pressure
Study 23484369 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18579230 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7920892 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study 7537110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7537110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7049582 — Surrogate Endpoint (SUR): Blood pressure
Study 26684265 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 25351765 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 11181655 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16564254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16564254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14602763 — Surrogate Endpoint (SUR): Bone mineral density
Study 14602763 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8775350 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8775350 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31905348 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 28695815 — Surrogate Endpoint (SUR): Blood pressure
Study 23223867 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 23223867 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19382426 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16906286 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27163986 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30102872 — Surrogate Endpoint (SUR): Bone mineral density
Study 23972276 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19474134 — Predictive Biomarker (PRD): CFLAR mRNA
Genes: CFLAR; CASH; CASP8AP1; CLARP; MRIT
Study 29381374 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 28277490 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 26590242 — Surrogate Endpoint (SUR): Blood pressure
Study 20092961 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 20092961 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 14521760 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31574029 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 26705327 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 18050245 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 7671564 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27417920 — Surrogate Endpoint (SUR): Serum creatinine
Study 11443192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11443192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11443192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11443192 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11443192 — Surrogate Endpoint (SUR): Serum testosterone
Study 8033141 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8033141 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 8033141 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21524316 — Surrogate Endpoint (SUR): Blood pressure
Study 16573163 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 29606109 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29606109 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29606109 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 29606109 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29606109 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 24191305 — Surrogate Endpoint (SUR): Serum potassium
Study 24191305 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24191305 — Surrogate Endpoint (SUR): Serum creatinine
Study 24191305 — Surrogate Endpoint (SUR): Blood pressure
Study 22301410 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22301410 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 22301410 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8583467 — Surrogate Endpoint (SUR): Blood pressure
Study 24739759 — Predictive Biomarker (PRD): LY75 mRNA
Genes: LY75; CD205; CLEC13B
Study 24739759 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 24739759 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 19065903 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 10892945 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1329478 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1329478 — Surrogate Endpoint (SUR): Blood pressure
Study 3864225 — Surrogate Endpoint (SUR): Blood pressure
Study 29860922 — Predictive Biomarker (PRD): Hormone receptor
Study 29860922 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19660268 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7590390 — Safety Biomarker (SAF): Cytochrome c
Study 7590390 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23743803 — Monitoring Biomarker (MOI): Procalcitonin
Study 23743803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23743803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23743803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20426759 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 20426759 — Safety Biomarker (SAF): Cytochrome c
Study 26559637 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24496699 — Surrogate Endpoint (SUR): Blood pressure
Study 19103535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19103535 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 19103535 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31774468 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 16676791 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 27636922 — Surrogate Endpoint (SUR): Blood pressure
Study 17950857 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 17950857 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 16258094 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 12079437 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12079437 — Surrogate Endpoint (SUR): Blood pressure
Study 8062153 — Surrogate Endpoint (SUR): Bone mineral density
Study 8062153 — Surrogate Endpoint (SUR): Serum calcium
Study 25641537 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24154787 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 22707609 — Safety Biomarker (SAF): Preexisting antibody
Study 9013103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9013103 — Safety Biomarker (SAF): Interleukin 1
Study 9013103 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 9013103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9013103 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21269578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19713451 — Surrogate Endpoint (SUR): Blood pressure
Study 16042672 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7840686 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 3122698 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 22834968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10556990 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10556990 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8753945 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1861487 — Surrogate Endpoint (SUR): Serum creatinine
Study 31689513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26493094 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26493094 — Predictive Biomarker (PRD): Hormone receptor
Study 20699022 — Predictive Biomarker (PRD): Microsatellite instability
Study 19220774 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 19220774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9572419 — Surrogate Endpoint (SUR): Sperm parameters
Study 17868436 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9374947 — Surrogate Endpoint (SUR): Blood pressure
Study 22245954 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22245954 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 22245954 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 15716696 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15716696 — Surrogate Endpoint (SUR): Blood pressure
Study 26607361 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 26607361 — Surrogate Endpoint (SUR): Blood pressure
Study 22329914 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11796177 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11796177 — Surrogate Endpoint (SUR): Blood pressure
Study 7486076 — Surrogate Endpoint (SUR): Blood pressure
Study 2178381 — Surrogate Endpoint (SUR): Blood pressure
Study 31455832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31455832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31455832 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31455832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24831447 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20632065 — Surrogate Endpoint (SUR): Bone mineral density
Study 27550959 — Surrogate Endpoint (SUR): Serum testosterone
Study 15857272 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15857272 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7758568 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11758006 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9750937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28841916 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 23726291 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30466845 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16896953 — Safety Biomarker (SAF): DRD3
Study 19609054 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19609054 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16003539 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1