TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27904554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18492125 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 14688560 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29455372 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 29455372 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16021438 — Surrogate Endpoint (SUR): Blood pressure
Study 8834418 — Predictive Biomarker (PRD): HPDL mRNA
Genes: HPDL; GLOXD1
Study 4017421 — Surrogate Endpoint (SUR): Blood pressure
Study 27863809 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25003166 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 20367560 — Surrogate Endpoint (SUR): Blood pressure
Study 12699301 — Surrogate Endpoint (SUR): Bone mineral density
Study 10626559 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 8665546 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8665546 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 16500361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16500361 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16500361 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10996336 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 10996336 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 2527542 — Surrogate Endpoint (SUR): Blood pressure
Study 26471240 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28899951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28899951 — Safety Biomarker (SAF): Interleukin 12
Study 28899951 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 1627437 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25153936 — Surrogate Endpoint (SUR): Blood pressure
Study 2253661 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2253661 — Surrogate Endpoint (SUR): Urine free cortisol
Study 23890352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 23890352 — Surrogate Endpoint (SUR): Bone mineral density
Study 22186252 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 22186252 — Predictive Biomarker (PRD): OAF mRNA
Genes: OAF; NS5ATP13TP2
Study 12850387 — Surrogate Endpoint (SUR): Blood pressure
Study 22212248 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 11686823 — Surrogate Endpoint (SUR): Probing pocket depth
Study 30055974 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27034624 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27034624 — Surrogate Endpoint (SUR): Blood pressure
Study 22241810 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 17534855 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 8712137 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8712137 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29727332 — Predictive Biomarker (PRD): Microsatellite instability
Study 29051561 — Predictive Biomarker (PRD): MAGT1 mRNA
Genes: MAGT1; IAG2; PSEC0084; UNQ628/PRO1244
Study 29051561 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 29051561 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 1289512 — Surrogate Endpoint (SUR): Blood pressure
Study 30091443 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 27103031 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 20166008 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1684154 — Surrogate Endpoint (SUR): Blood pressure
Study 26644369 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7743684 — Surrogate Endpoint (SUR): Blood pressure
Study 28590358 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9575677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 9575677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 2907823 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26892612 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 26892612 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20578534 — Surrogate Endpoint (SUR): Blood pressure
Study 18234086 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 18234086 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9170421 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8400752 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 8400752 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2891369 — Surrogate Endpoint (SUR): Blood pressure
Study 23026132 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 16918591 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27297843 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 23350191 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23350191 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12145072 — Surrogate Endpoint (SUR): Blood pressure
Study 10335872 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10335872 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 7780060 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7780060 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2081012 — Surrogate Endpoint (SUR): Blood pressure
Study 14998841 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 27560256 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27560256 — Surrogate Endpoint (SUR): Blood pressure
Study 27560256 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27560256 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27755543 — Surrogate Endpoint (SUR): Blood pressure
Study 3987071 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30418164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15374489 — Surrogate Endpoint (SUR): Blood pressure
Study 31755550 — Surrogate Endpoint (SUR): Blood pressure
Study 14602740 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14602740 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1361935 — Surrogate Endpoint (SUR): Blood pressure
Study 29156378 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29156378 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23144467 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 23144467 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 20229018 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 15757934 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 3127028 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30610781 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 19717480 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15966880 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22244160 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22244160 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16022847 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12243438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 799558 — Surrogate Endpoint (SUR): Blood pressure
Study 31441836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31441836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26055067 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 23075691 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27849355 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27849355 — Safety Biomarker (SAF): BDNF
Study 24859364 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24859364 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 27072796 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 27072796 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 19583673 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29033108 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 29033108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7511501 — Surrogate Endpoint (SUR): Blood pressure
Study 23053269 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 23053269 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9181181 — Surrogate Endpoint (SUR): Blood pressure
Study 2994577 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 29956072 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 29985447 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 27018037 — Surrogate Endpoint (SUR): Bone mineral density
Study 23856575 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 9366281 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18839777 — Surrogate Endpoint (SUR): Serum creatinine
Study 8773910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8773910 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8773910 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8773910 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 8773910 — Safety Biomarker (SAF): Interleukin 1
Study 1312854 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31493297 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31102396 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 20635176 — Surrogate Endpoint (SUR): Blood pressure
Study 12040140 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19854960 — Safety Biomarker (SAF): Hyaluronic acid
Study 11418255 — Surrogate Endpoint (SUR): Blood pressure
Study 20127562 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 18318082 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15942467 — Surrogate Endpoint (SUR): Blood pressure
Study 22245891 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22245891 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22245891 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22245891 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11918884 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22872229 — Surrogate Endpoint (SUR): Blood pressure
Study 6463176 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 14984925 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 14984925 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23990706 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23990706 — Surrogate Endpoint (SUR): Blood pressure
Study 16729277 — Surrogate Endpoint (SUR): Bone mineral density
Study 11343737 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11343737 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 7988783 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 23592479 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28807031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26331623 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17947500 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17947500 — Pharmacodynamic Biomarker (PDY): Pyruvate dehydrogenase kinase 1
Genes: PDK1; PDHK1
Study 12831948 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12831948 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10232311 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1988077 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1988077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1988077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1988077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2876664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30054049 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28662222 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28662222 — Predictive Biomarker (PRD): Hormone receptor
Study 21196894 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10770187 — Surrogate Endpoint (SUR): Bone mineral density
Study 8393108 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18847422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16635293 — Monitoring Biomarker (MOI): HBV DNA
Study 31237044 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31237044 — Predictive Biomarker (PRD): E2F1 mRNA
Genes: E2F1; RBBP3
Study 31237044 — Predictive Biomarker (PRD): PSMD8 mRNA
Genes: PSMD8
Study 31237044 — Predictive Biomarker (PRD): AXIN1 mRNA
Genes: AXIN1; AXIN
Study 31237044 — Predictive Biomarker (PRD): GAB2 mRNA
Genes: GAB2; KIAA0571
Study 16875919 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16875919 — Surrogate Endpoint (SUR): Blood pressure
Study 9177376 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9177376 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9177376 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9177376 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26559681 — Safety Biomarker (SAF): MTHFR
Study 26559681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24655701 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24655701 — Surrogate Endpoint (SUR): Blood pressure
Study 21088807 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16372585 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 16372585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11497156 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8221579 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 30289006 — Surrogate Endpoint (SUR): Blood pressure
Study 29873709 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29873709 — Surrogate Endpoint (SUR): Blood pressure
Study 22854402 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22854402 — Surrogate Endpoint (SUR): Blood pressure
Study 10476945 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29753661 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 29753661 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 26902276 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 26902276 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 26902276 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25465181 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23769863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23769863 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10620000 — Surrogate Endpoint (SUR): Blood pressure
Study 8620093 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8620093 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24946630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24946630 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24946630 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 24946630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24946630 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 24946630 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24946630 — Safety Biomarker (SAF): IL-6 and IL-10
Study 23066737 — Surrogate Endpoint (SUR): Blood pressure
Study 16116046 — Surrogate Endpoint (SUR): Blood pressure
Study 9576125 — Surrogate Endpoint (SUR): Blood pressure
Study 8584772 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2236433 — Surrogate Endpoint (SUR): Blood pressure
Study 30497684 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30497684 — Surrogate Endpoint (SUR): Blood pressure
Study 27986549 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 27986549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27986549 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20135132 — Safety Biomarker (SAF): Hyaluronic acid
Study 11402910 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11402910 — Surrogate Endpoint (SUR): Blood pressure
Study 22585884 — Surrogate Endpoint (SUR): Blood pressure
Study 17645076 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 29169838 — Surrogate Endpoint (SUR): Blood pressure
Study 23269286 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 23269286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11902023 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21982649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19238654 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 19238654 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 10882574 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8807623 — Surrogate Endpoint (SUR): Bone mineral density
Study 31256445 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20061913 — Surrogate Endpoint (SUR): Serum creatinine
Study 16051709 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 11973410 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20926021 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10597554 — Surrogate Endpoint (SUR): Serum sodium
Study 8605791 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7649596 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 26058489 — Surrogate Endpoint (SUR): Bone mineral density
Study 23834132 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 21745625 — Surrogate Endpoint (SUR): Blood pressure
Study 19880459 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 19880459 — Predictive Biomarker (PRD): GRIK4 mRNA
Genes: GRIK4; GRIK
Study 19880459 — Predictive Biomarker (PRD): KCNAB2 mRNA
Genes: KCNAB2; KCNA2B; KCNK2
Study 19880459 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 19880459 — Predictive Biomarker (PRD): PDE11A mRNA
Genes: PDE11A
Study 19880459 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19880459 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 19880459 — Predictive Biomarker (PRD): GRIA3 mRNA
Genes: GRIA3; GLUR3; GLURC
Study 19880459 — Predictive Biomarker (PRD): PAPLN mRNA
Genes: PAPLN; UNQ2420/PRO4977
Study 1544289 — Surrogate Endpoint (SUR): Blood pressure
Study 4054204 — Surrogate Endpoint (SUR): Blood pressure
Study 29914666 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29914666 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29914666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29914666 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 29914666 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 29914666 — Surrogate Endpoint (SUR): Blood pressure
Study 9856962 — Surrogate Endpoint (SUR): Blood pressure
Study 30265586 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 28069040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28069040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8437596 — Safety Biomarker (SAF): Interleukin 1
Study 18341673 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10606361 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 31865336 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 31865336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1