TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26024532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10825372 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 10825372 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 10825372 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 10825372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 10825372 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 10825372 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20444448 — Surrogate Endpoint (SUR): Bone mineral density
Study 12539003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12539003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12539003 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 12539003 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12539003 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8884643 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 28216550 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24100259 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 19214890 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 3902176 — Surrogate Endpoint (SUR): Blood pressure
Study 26148364 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 22785001 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 18186265 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 14669282 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 30557342 — Predictive Biomarker (PRD): C1QTNF3 mRNA
Genes: C1QTNF3; CTRP3; UNQ753/PRO1484
Study 30557342 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 30557342 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27095446 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21805294 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21805294 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15309001 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12040470 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28044948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20977584 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20977584 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15794797 — Surrogate Endpoint (SUR): Serum creatinine
Study 8767527 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 8767527 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 1678570 — Surrogate Endpoint (SUR): Blood pressure
Study 22865778 — Predictive Biomarker (PRD): Microsatellite instability
Study 31550915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23438946 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 15054349 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15054349 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15054349 — Surrogate Endpoint (SUR): Blood pressure
Study 29044725 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 20602260 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9683118 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9160569 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 31134657 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 24045099 — Surrogate Endpoint (SUR): Blood pressure
Study 11498312 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17111013 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 17111013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 17111013 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17111013 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17111013 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11329095 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11329095 — Surrogate Endpoint (SUR): Blood pressure
Study 7753432 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 21745769 — Surrogate Endpoint (SUR): Bacterial count
Study 23683569 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 19615135 — Monitoring Biomarker (MOI): Procalcitonin
Study 19615135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19615135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2972540 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19230906 — Predictive Biomarker (PRD): PRPH2 mRNA
Genes: PRPH2; PRPH; RDS; TSPAN22
Study 6100260 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3033966 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23615823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23615823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14576512 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2072368 — Surrogate Endpoint (SUR): Blood pressure
Study 27059799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18628618 — Predictive Biomarker (PRD): NOS3 mRNA
Genes: NOS3
Study 11315826 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11315826 — Surrogate Endpoint (SUR): Blood pressure
Study 7868871 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7868871 — Surrogate Endpoint (SUR): Blood pressure
Study 23834402 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 23834402 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 21756382 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 21756382 — Surrogate Endpoint (SUR): Serum testosterone
Study 21756382 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 19629060 — Surrogate Endpoint (SUR): Bone mineral density
Study 16611682 — Surrogate Endpoint (SUR): Serum creatinine
Study 16611682 — Surrogate Endpoint (SUR): Blood pressure
Study 320955 — Surrogate Endpoint (SUR): Blood pressure
Study 25349107 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 22285168 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31349110 — Surrogate Endpoint (SUR): Blood pressure
Study 22458939 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2506490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30844048 — Surrogate Endpoint (SUR): Serum uric acid
Study 22732180 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18042311 — Surrogate Endpoint (SUR): Bone mineral density
Study 11179910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26588809 — Surrogate Endpoint (SUR): Bone mineral density
Study 19851858 — Predictive Biomarker (PRD): Microsatellite instability
Study 11861035 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9732842 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30557370 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24081439 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 31955013 — Surrogate Endpoint (SUR): Blood pressure
Study 31955013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31955013 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23265352 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 27397838 — Predictive Biomarker (PRD): EBP mRNA
Genes: EBP
Study 10450289 — Surrogate Endpoint (SUR): Blood pressure
Study 1746296 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1746296 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30724405 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 6117576 — Surrogate Endpoint (SUR): Blood pressure
Study 21136310 — Predictive Biomarker (PRD): MPG mRNA
Genes: MPG; AAG; ANPG; MID1
Study 21136310 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9081852 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22811376 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22811376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15036828 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26202994 — Surrogate Endpoint (SUR): Blood pressure
Study 9051332 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 10515442 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10515442 — Surrogate Endpoint (SUR): Blood pressure
Study 29471922 — Surrogate Endpoint (SUR): Blood pressure
Study 16103896 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 16103896 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12370520 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7572006 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7572006 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7270401 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7270401 — Surrogate Endpoint (SUR): Blood pressure
Study 22402068 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18663625 — Surrogate Endpoint (SUR): Blood pressure
Study 18663625 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18663625 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3853254 — Surrogate Endpoint (SUR): Blood pressure
Study 21999138 — Safety Biomarker (SAF): Hyaluronic acid
Study 6496995 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12850395 — Surrogate Endpoint (SUR): Blood pressure
Study 10593371 — Surrogate Endpoint (SUR): Blood pressure
Study 19961932 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16903931 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 29384321 — Surrogate Endpoint (SUR): Blood pressure
Study 29384321 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16120821 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11865366 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 492050 — Surrogate Endpoint (SUR): Blood pressure
Study 25889304 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15533488 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9659838 — Surrogate Endpoint (SUR): Blood pressure
Study 28067195 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 26031921 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22350036 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12692182 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 12692182 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18779278 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1934591 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1934591 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30689402 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28166116 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19132412 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15448032 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10353887 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6627819 — Surrogate Endpoint (SUR): Blood pressure
Study 25247320 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22770926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2720018 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30556110 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 9496202 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 28019134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19276275 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 9163261 — Surrogate Endpoint (SUR): Blood pressure
Study 3108429 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3108429 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 18482245 — Surrogate Endpoint (SUR): Blood pressure
Study 23025844 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19674927 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 27510285 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 20932272 — Surrogate Endpoint (SUR): Bone mineral density
Study 10102462 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10102462 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12639763 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 12639763 — Surrogate Endpoint (SUR): Blood pressure
Study 10928223 — Surrogate Endpoint (SUR): Bone mineral density
Study 26890438 — Surrogate Endpoint (SUR): Blood pressure
Study 24055515 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 22057579 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22057579 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 22057579 — Predictive Biomarker (PRD): HSPA1A mRNA
Genes: HSPA1A; HSP72; HSPA1; HSX70
Study 22057579 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 19288181 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8852495 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8852495 — Surrogate Endpoint (SUR): Blood pressure
Study 31004340 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 23857036 — Surrogate Endpoint (SUR): Blood pressure
Study 22633423 — Surrogate Endpoint (SUR): Blood pressure
Study 17678487 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27781388 — Surrogate Endpoint (SUR): Blood pressure
Study 20820817 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17869297 — Surrogate Endpoint (SUR): Serum sodium
Study 8111799 — Surrogate Endpoint (SUR): Blood pressure
Study 27823800 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26056336 — Surrogate Endpoint (SUR): Blood pressure
Study 15113814 — Surrogate Endpoint (SUR): Blood pressure
Study 9150899 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 3500051 — Surrogate Endpoint (SUR): Plasma methotrexate
Study 19259830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24531602 — Surrogate Endpoint (SUR): Blood pressure
Study 22374408 — Predictive Biomarker (PRD): FFAR1 mRNA
Genes: FFAR1; GPR40
Study 11015237 — Surrogate Endpoint (SUR): Blood pressure
Study 31175052 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24872326 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17852827 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17852827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8879847 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 22392817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22392817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15855258 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15855258 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10374456 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 7837152 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7837152 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3534593 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18098237 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7040955 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30069803 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24387048 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 17237312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10368879 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10368879 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7046434 — Surrogate Endpoint (SUR): Serum creatinine
Study 31092172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29223955 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29223955 — Surrogate Endpoint (SUR): Serum creatinine
Study 25339309 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 14713325 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14713325 — Surrogate Endpoint (SUR): Blood pressure
Study 9118514 — Surrogate Endpoint (SUR): Blood pressure
Study 8419392 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30866659 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 17381970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14980936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11446564 — Surrogate Endpoint (SUR): Bone mineral density
Study 30646422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 30646422 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 30646422 — Surrogate Endpoint (SUR): Blood pressure
Study 9834590 — Surrogate Endpoint (SUR): Blood pressure
Study 28902073 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28902073 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 26168736 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26168736 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26168736 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 26168736 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 26168736 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 21600129 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 21600129 — Surrogate Endpoint (SUR): Blood pressure
Study 12904840 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 12904840 — Surrogate Endpoint (SUR): Bone mineral density
Study 4103276 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 7503838 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17679044 — Surrogate Endpoint (SUR): Blood pressure
Study 17679044 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15385805 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9829346 — Surrogate Endpoint (SUR): Blood pressure
Study 9829346 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29335039 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29335039 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 19067474 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2442538 — Surrogate Endpoint (SUR): Blood pressure
Study 14604194 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9148240 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 29713800 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29713800 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 29713800 — Surrogate Endpoint (SUR): Blood pressure
Study 27658756 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 26351027 — Surrogate Endpoint (SUR): Blood pressure
Study 15129927 — Surrogate Endpoint (SUR): Bone mineral density
Study 11304901 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 9345339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9345339 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2