TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27154357 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 20232413 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 2073669 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27627193 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17417917 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15244246 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15244246 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2869001 — Surrogate Endpoint (SUR): Blood pressure
Study 30324553 — Monitoring Biomarker (MOI): HBV DNA
Study 29263660 — Predictive Biomarker (PRD): CLN8 mRNA
Genes: CLN8; C8orf61
Study 29263660 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 29263660 — Predictive Biomarker (PRD): SKP2 mRNA
Genes: SKP2; FBXL1
Study 29263660 — Predictive Biomarker (PRD): SPTBN5 mRNA
Genes: SPTBN5; BSPECV; HUBSPECV; HUSPECV
Study 29263660 — Predictive Biomarker (PRD): C1orf115 mRNA
Genes: C1orf115; RDD1
Study 29263660 — Predictive Biomarker (PRD): RNF213 mRNA
Genes: RNF213; ALO17; C17orf27; KIAA1554; KIAA1618; MYSTR
Study 29263660 — Predictive Biomarker (PRD): PRKX mRNA
Genes: PRKX; PKX1
Study 29263660 — Predictive Biomarker (PRD): RHOQ mRNA
Genes: RHOQ; ARHQ; RASL7A; TC10
Study 29263660 — Predictive Biomarker (PRD): FBN3 mRNA
Genes: FBN3; KIAA1776
Study 26388284 — Surrogate Endpoint (SUR): Blood pressure
Study 21719695 — Surrogate Endpoint (SUR): Serum testosterone
Study 20178254 — Monitoring Biomarker (MOI): HBV DNA
Study 7493423 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1674394 — Surrogate Endpoint (SUR): Blood pressure
Study 15247338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29575406 — Surrogate Endpoint (SUR): Blood pressure
Study 20826878 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 16872795 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 10933350 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10933350 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 4042547 — Surrogate Endpoint (SUR): Blood pressure
Study 30007343 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 30007343 — Surrogate Endpoint (SUR): Bone mineral density
Study 22898365 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18602144 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30917287 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28791808 — Safety Biomarker (SAF): Hyaluronic acid
Study 23569894 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12629102 — Surrogate Endpoint (SUR): Serum calcium
Study 31853709 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 31820361 — Surrogate Endpoint (SUR): Blood pressure
Study 31820361 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31820361 — Surrogate Endpoint (SUR): Serum potassium
Study 28562541 — Surrogate Endpoint (SUR): Blood pressure
Study 11588440 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25231953 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25231953 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25231953 — Predictive Biomarker (PRD): Hormone receptor
Study 21164551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21164551 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21164551 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10208997 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2183599 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2183599 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31142441 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28196207 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 28196207 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 28196207 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 19388569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31444897 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 8776643 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 6749207 — Surrogate Endpoint (SUR): Blood pressure
Study 24573180 — Surrogate Endpoint (SUR): Blood pressure
Study 20102936 — Surrogate Endpoint (SUR): Serum creatinine
Study 15892275 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10404806 — Surrogate Endpoint (SUR): Bone mineral density
Study 2202385 — Surrogate Endpoint (SUR): Blood pressure
Study 22456951 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11113837 — Predictive Biomarker (PRD): LAX1 mRNA
Genes: LAX1; LAX
Study 3524724 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 24755192 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 24755192 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 18294482 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27067393 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 31388184 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 31388184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29702040 — Surrogate Endpoint (SUR): Blood pressure
Study 29702040 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29702040 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22134624 — Surrogate Endpoint (SUR): Bone mineral density
Study 16008934 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3918145 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22712480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22712480 — Surrogate Endpoint (SUR): Blood pressure
Study 15522901 — Surrogate Endpoint (SUR): Blood pressure
Study 12576840 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31689480 — Surrogate Endpoint (SUR): Serum creatinine
Study 27761657 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 27761657 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 27761657 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27761657 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 27761657 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 27761657 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 27761657 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18619520 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 30911917 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 29847468 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29847468 — Safety Biomarker (SAF): BDNF
Study 19396947 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 19396947 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19396947 — Safety Biomarker (SAF): Reactive oxygen species
Study 29070025 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 19629889 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16388789 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16388789 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7803945 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7803945 — Surrogate Endpoint (SUR): Blood pressure
Study 3190040 — Surrogate Endpoint (SUR): Serum creatinine
Study 29778251 — Surrogate Endpoint (SUR): Blood pressure
Study 16580422 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2822797 — Surrogate Endpoint (SUR): Blood pressure
Study 28153938 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19403954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 7667819 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25799193 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 25799193 — Surrogate Endpoint (SUR): Bone mineral density
Study 16176337 — Surrogate Endpoint (SUR): Blood pressure
Study 12939217 — Surrogate Endpoint (SUR): Blood pressure
Study 21951682 — Surrogate Endpoint (SUR): Serum creatinine
Study 18504393 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17140161 — Surrogate Endpoint (SUR): Serum creatinine
Study 20187284 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 20187284 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 20187284 — Predictive Biomarker (PRD): MYOD1 mRNA
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 18165639 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15624096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 7583806 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2179286 — Surrogate Endpoint (SUR): Blood pressure
Study 30944359 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 11254825 — Surrogate Endpoint (SUR): Bone mineral density
Study 3049338 — Surrogate Endpoint (SUR): Blood pressure
Study 11113722 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31238715 — Surrogate Endpoint (SUR): Blood pressure
Study 20129545 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27491607 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31909561 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30418217 — Surrogate Endpoint (SUR): Serum creatinine
Study 18171953 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 9892252 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 7841356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7841356 — Safety Biomarker (SAF): Interleukin 1
Study 29921730 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 29921730 — Predictive Biomarker (PRD): CACNA1G mRNA
Genes: CACNA1G; KIAA1123
Study 29921730 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 29921730 — Predictive Biomarker (PRD): RUNX3 mRNA
Genes: RUNX3; AML2; CBFA3; PEBP2A3
Study 28679643 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20356582 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 12907530 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11967720 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11967720 — Surrogate Endpoint (SUR): Blood pressure
Study 30366577 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28091446 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26106113 — Surrogate Endpoint (SUR): Blood pressure
Study 23266331 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 23266331 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 17418727 — Predictive Biomarker (PRD): FER mRNA
Genes: FER; TYK3
Study 17418727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7616279 — Surrogate Endpoint (SUR): Bone mineral density
Study 31407549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31407549 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31407549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17719314 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20979675 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8839231 — Surrogate Endpoint (SUR): Blood pressure
Study 2123819 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 23623841 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 15519288 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 11302460 — Predictive Biomarker (PRD): RBFOX2 mRNA
Genes: RBFOX2; FOX2; HRNBP2; RBM9; RTA
Study 19046249 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15531318 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 8072721 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 8072721 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8072721 — Surrogate Endpoint (SUR): Blood pressure
Study 21166722 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 16597078 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22485232 — Monitoring Biomarker (MOI): Procalcitonin
Study 15083597 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15083597 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25034387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25034387 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25034387 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 3894971 — Surrogate Endpoint (SUR): Blood pressure
Study 23203140 — Surrogate Endpoint (SUR): Blood pressure
Study 14508032 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 14508032 — Surrogate Endpoint (SUR): Blood pressure
Study 28315283 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 25688512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25688512 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 22390264 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 19205290 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 7775859 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7775859 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 121884 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23951335 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 23951335 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 11499735 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11499735 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8387151 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 8387151 — Surrogate Endpoint (SUR): Blood pressure
Study 2820329 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2820329 — Surrogate Endpoint (SUR): Blood pressure
Study 27924521 — Surrogate Endpoint (SUR): Blood pressure
Study 20459404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20459404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10598610 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20388624 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 1538559 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 29702283 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 22991405 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 20415618 — Surrogate Endpoint (SUR): Blood pressure
Study 10226125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 10226125 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8967669 — Surrogate Endpoint (SUR): Blood pressure
Study 1725890 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 1725890 — Surrogate Endpoint (SUR): Blood pressure
Study 11526363 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11526363 — Surrogate Endpoint (SUR): Blood pressure
Study 28399112 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28399112 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 23500537 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19216016 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26429398 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26429398 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22946635 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 21658884 — Surrogate Endpoint (SUR): Blood pressure
Study 11700399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8008999 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28804223 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28804223 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28804223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28804223 — Safety Biomarker (SAF): Interleukin 1
Study 28804223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28804223 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28804223 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31346609 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 29137041 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 10637151 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10637151 — Surrogate Endpoint (SUR): Blood pressure
Study 29231607 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21470248 — Surrogate Endpoint (SUR): Blood pressure
Study 9268948 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 8274720 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27629844 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 26677667 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 26677667 — Predictive Biomarker (PRD): ACTA1 mRNA
Genes: ACTA1; ACTA
Study 17139367 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 17139367 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8383874 — Surrogate Endpoint (SUR): Blood pressure
Study 26061686 — Predictive Biomarker (PRD): BTN1A1 mRNA
Genes: BTN1A1; BTN
Study 23752780 — Surrogate Endpoint (SUR): Blood pressure
Study 12411452 — Surrogate Endpoint (SUR): Blood pressure
Study 12411452 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12411452 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6411792 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9146858 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9146858 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 6498701 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 30763661 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 2487529 — Surrogate Endpoint (SUR): Blood pressure
Study 2487529 — Surrogate Endpoint (SUR): Serum potassium
Study 19929597 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20512334 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 20512334 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 20512334 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 16759924 — Predictive Biomarker (PRD): IL2RG mRNA
Genes: IL2RG
Study 16759924 — Predictive Biomarker (PRD): LOXL1 mRNA
Genes: LOXL1; LOXL
Study 14657226 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 9209644 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 9209644 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 26553236 — Surrogate Endpoint (SUR): Blood pressure
Study 17658393 — Surrogate Endpoint (SUR): Blood pressure
Study 2107743 — Surrogate Endpoint (SUR): Blood pressure
Study 30239017 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 26547351 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 14748891 — Surrogate Endpoint (SUR): Bone mineral density
Study 14748891 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 2733125 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2733125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31074844 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study 20564086 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 20564086 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 12355576 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20662726 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18760151 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 15903362 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9796239 — Surrogate Endpoint (SUR): Blood pressure
Study 2533763 — Surrogate Endpoint (SUR): Blood pressure
Study 31109415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31109415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26258314 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21751661 — Surrogate Endpoint (SUR): Serum uric acid
Study 21751661 — Surrogate Endpoint (SUR): Blood pressure
Study 9382669 — Surrogate Endpoint (SUR): Bone mineral density
Study 28974267 — Surrogate Endpoint (SUR): Bone mineral density
Study 23980737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23980737 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 23980737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2