TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15070944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11240978 — Safety Biomarker (SAF): Hypoxanthine-guanine phosphoribosyltransferase
Genes: HPRT1; HPRT
Study 27130167 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22552687 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9032106 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9032106 — Surrogate Endpoint (SUR): Blood pressure
Study 9032106 — Safety Biomarker (SAF): 51Cr-EDTA
Study 10148570 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 31876749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31711528 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24535415 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 28382877 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 28382877 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 28382877 — Predictive Biomarker (PRD): NADSYN1 mRNA
Genes: NADSYN1
Study 28382877 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 25773378 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25773378 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22090268 — Surrogate Endpoint (SUR): Serum calcium
Study 18175733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15920044 — Surrogate Endpoint (SUR): Blood pressure
Study 29074892 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10749030 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10749030 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10749030 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8583020 — Surrogate Endpoint (SUR): Probing pocket depth
Study 28982775 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 23424242 — Surrogate Endpoint (SUR): Blood pressure
Study 15081447 — Surrogate Endpoint (SUR): Blood pressure
Study 11394242 — Surrogate Endpoint (SUR): Serum testosterone
Study 3056503 — Surrogate Endpoint (SUR): Blood pressure
Study 15840256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15840256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31894102 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31894102 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 31894102 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 30857843 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 30857843 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 30857843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30857843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28509934 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 12732605 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10924732 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20215781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20215781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10720082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24448692 — Surrogate Endpoint (SUR): Blood pressure
Study 21781149 — Surrogate Endpoint (SUR): Blood pressure
Study 15821394 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17313001 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 6337003 — Surrogate Endpoint (SUR): Blood pressure
Study 18173139 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 28222178 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28222178 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22867975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22867975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22867975 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 21193172 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 12446059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12446059 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10473840 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31377226 — Predictive Biomarker (PRD): AQP5 mRNA
Genes: AQP5
Study 30390409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22906006 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12584670 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12584670 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 12584670 — Surrogate Endpoint (SUR): Serum creatinine
Study 12584670 — Surrogate Endpoint (SUR): Blood pressure
Study 14514397 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 29572795 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 16717300 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 3994010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19414572 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 9520826 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9520826 — Surrogate Endpoint (SUR): Serum sodium
Study 30451582 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16686906 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 15490785 — Surrogate Endpoint (SUR): Blood pressure
Study 31371114 — Surrogate Endpoint (SUR): Blood pressure
Study 20484128 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 18713923 — Surrogate Endpoint (SUR): Blood pressure
Study 16477766 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31612909 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26011779 — Surrogate Endpoint (SUR): Blood pressure
Study 23230975 — Surrogate Endpoint (SUR): Serum creatinine
Study 16490891 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16490891 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10613410 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7583255 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29429541 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 29429541 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20576419 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 20576419 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12453546 — Surrogate Endpoint (SUR): Blood pressure
Study 29800370 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22234929 — Surrogate Endpoint (SUR): Blood pressure
Study 25265255 — Surrogate Endpoint (SUR): Serum creatinine
Study 10918483 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 19917839 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17029996 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10709897 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7529606 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7529606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7529606 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 30016417 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28672073 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28672073 — Safety Biomarker (SAF): BDNF
Study 26582144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9174677 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8251730 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20567009 — Surrogate Endpoint (SUR): Bone mineral density
Study 20567009 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16042732 — Surrogate Endpoint (SUR): Serum sodium
Study 16042732 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8403135 — Surrogate Endpoint (SUR): Blood pressure
Study 4028514 — Surrogate Endpoint (SUR): Blood pressure
Study 10355479 — Surrogate Endpoint (SUR): Blood pressure
Study 17342998 — Surrogate Endpoint (SUR): Blood pressure
Study 7884745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7884745 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 28695567 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 16631435 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 4053509 — Surrogate Endpoint (SUR): Blood pressure
Study 15752943 — Surrogate Endpoint (SUR): Blood pressure
Study 12022434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1758240 — Surrogate Endpoint (SUR): Blood pressure
Study 22461375 — Surrogate Endpoint (SUR): Blood pressure
Study 20619624 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8006396 — Monitoring Biomarker (MOI): HBV DNA
Study 2573379 — Surrogate Endpoint (SUR): Blood pressure
Study 29260533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29260533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29260533 — Monitoring Biomarker (MOI): Procalcitonin
Study 29260533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29260533 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25149364 — Surrogate Endpoint (SUR): Blood pressure
Study 16791115 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 16791115 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 16791115 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 16791115 — Predictive Biomarker (PRD): ABCC4 mRNA
Genes: ABCC4; MOATB; MRP4
Study 14581931 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 28811749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23217729 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 11751710 — Surrogate Endpoint (SUR): Blood pressure
Study 9252087 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9252087 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18545068 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9148534 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29258851 — Safety Biomarker (SAF): Hyaluronic acid
Study 23006960 — Surrogate Endpoint (SUR): Blood pressure
Study 30400858 — Surrogate Endpoint (SUR): Blood pressure
Study 25715484 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17541206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17541206 — Surrogate Endpoint (SUR): Blood pressure
Study 15738287 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 22505251 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 21829501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21829501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21829501 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16758382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14561107 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10988100 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10988100 — Predictive Biomarker (PRD): RNASE2 mRNA
Genes: RNASE2; EDN; RNS2
Study 22974968 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12749830 — Surrogate Endpoint (SUR): Serum potassium
Study 12749830 — Surrogate Endpoint (SUR): Blood pressure
Study 26885697 — Surrogate Endpoint (SUR): Bone mineral density
Study 8228194 — Surrogate Endpoint (SUR): Blood pressure
Study 8228194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28992224 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28992224 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 28992224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28992224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25022840 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 25022840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25022840 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 15661551 — Predictive Biomarker (PRD): Hormone receptor
Study 28531361 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 28531361 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20103777 — Surrogate Endpoint (SUR): Serum potassium
Study 20409883 — Surrogate Endpoint (SUR): Blood pressure
Study 25347930 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 17459739 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 29658845 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 29658845 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 20888255 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19180322 — Surrogate Endpoint (SUR): Probing pocket depth
Study 30672056 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30672056 — Predictive Biomarker (PRD): Hormone receptor
Study 16216977 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16216977 — Surrogate Endpoint (SUR): Blood pressure
Study 8006923 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21975275 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9419773 — Surrogate Endpoint (SUR): Blood pressure
Study 8645022 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 23936895 — Predictive Biomarker (PRD): MSN mRNA
Genes: MSN
Study 10512913 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31500510 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 19390750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21204677 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 1905472 — Surrogate Endpoint (SUR): Serum creatinine
Study 30918032 — Safety Biomarker (SAF): Fibroblast growth factor 1
Genes: FGF1
Study 2674593 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28141698 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24432676 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 10082241 — Surrogate Endpoint (SUR): Blood pressure
Study 31260678 — Predictive Biomarker (PRD): PNPLA2 mRNA
Genes: PNPLA2; ATGL; FP17548
Study 31260678 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 31260678 — Predictive Biomarker (PRD): PLIN1 mRNA
Genes: PLIN1; PERI; PLIN
Study 31260678 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 21883530 — Surrogate Endpoint (SUR): Blood pressure
Study 21883530 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21883530 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18178245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10710121 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 25761488 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19800671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19800671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19800671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8436150 — Surrogate Endpoint (SUR): Blood pressure
Study 22897374 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 22897374 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22897374 — Surrogate Endpoint (SUR): Blood pressure
Study 20708634 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 9487427 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8398959 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2439803 — Surrogate Endpoint (SUR): Blood pressure
Study 12927624 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12927624 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 12927624 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 27634952 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 25670764 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 19903780 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19903780 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19903780 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 16518754 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 12184546 — Surrogate Endpoint (SUR): Serum calcium
Study 21310819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17179269 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 22727160 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19719551 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19719551 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 8646433 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 30004561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30004561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30004561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24834977 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7141761 — Surrogate Endpoint (SUR): Blood pressure
Study 27501160 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27501160 — Surrogate Endpoint (SUR): Blood pressure
Study 16120823 — Surrogate Endpoint (SUR): Blood pressure
Study 16120823 — Surrogate Endpoint (SUR): Serum creatinine
Study 14506391 — Monitoring Biomarker (MOI): HBV DNA
Study 29261568 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29261568 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25203878 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 7004723 — Surrogate Endpoint (SUR): Blood pressure
Study 17647293 — Monitoring Biomarker (MOI): HBV DNA
Study 12195129 — Surrogate Endpoint (SUR): Blood pressure
Study 7182376 — Surrogate Endpoint (SUR): Blood pressure
Study 24220392 — Safety Biomarker (SAF): Hyaluronic acid
Study 15303131 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 15303131 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7723546 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7035040 — Surrogate Endpoint (SUR): Blood pressure
Study 24352352 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15887425 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15887425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25735442 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8612408 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2859861 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15595331 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 12431962 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2996444 — Surrogate Endpoint (SUR): Serum potassium
Study 28229572 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22221724 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 31442336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31442336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31442336 — Safety Biomarker (SAF): IL-6 and IL-10
Study 27977057 — Predictive Biomarker (PRD): CD37 mRNA
Genes: CD37; TSPAN26
Study 11779917 — Surrogate Endpoint (SUR): Blood pressure
Study 7508219 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27017701 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27017701 — Safety Biomarker (SAF): BDNF