TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27279571 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21449785 — Surrogate Endpoint (SUR): Bone mineral density
Study 10052484 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7866820 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 11836674 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 16030123 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 16030123 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 8770775 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30578395 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 21030879 — Surrogate Endpoint (SUR): Blood pressure
Study 21030879 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21030879 — Surrogate Endpoint (SUR): Serum potassium
Study 16943794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16943794 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1318081 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23868944 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20544245 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11022900 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11022900 — Surrogate Endpoint (SUR): Blood pressure
Study 1352564 — Surrogate Endpoint (SUR): Serum creatinine
Study 29602791 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26582520 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 22325110 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11980678 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 1597844 — Surrogate Endpoint (SUR): Blood pressure
Study 30264178 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26216382 — Surrogate Endpoint (SUR): Serum uric acid
Study 26216382 — Surrogate Endpoint (SUR): Serum creatinine
Study 20712602 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 31774950 — Surrogate Endpoint (SUR): Serum creatinine
Study 25867847 — Safety Biomarker (SAF): Cytochrome c
Study 18317624 — Surrogate Endpoint (SUR): Blood pressure
Study 27966508 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17920365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17920365 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7668935 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2401750 — Surrogate Endpoint (SUR): Blood pressure
Study 31789006 — Surrogate Endpoint (SUR): Blood pressure
Study 15237694 — Safety Biomarker (SAF): RFC1
Genes: A1; PO-GA; RFC140; MHCBFB
Study 22776420 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22776420 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18266604 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 11416735 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30156200 — Safety Biomarker (SAF): Interleukin 1
Study 30156200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26363048 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 19012865 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19012865 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12902634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11381293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9142006 — Surrogate Endpoint (SUR): Blood pressure
Study 9142006 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16670077 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24392703 — Surrogate Endpoint (SUR): Serum testosterone
Study 12509214 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 7891796 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7891796 — Surrogate Endpoint (SUR): Blood pressure
Study 7891796 — Surrogate Endpoint (SUR): Serum potassium
Study 8420311 — Surrogate Endpoint (SUR): Bone mineral density
Study 3736737 — Surrogate Endpoint (SUR): Blood pressure
Study 31810613 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 27098150 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21123458 — Safety Biomarker (SAF): MTHFR
Study 18355770 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 16310388 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14567443 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 14567443 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 14567443 — Safety Biomarker (SAF): Reactive oxygen species
Study 1441789 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31295334 — Predictive Biomarker (PRD): PROCR mRNA
Genes: PROCR; EPCR
Study 9434647 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28846481 — Safety Biomarker (SAF): Hyaluronic acid
Study 3117566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19342295 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27381263 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 1428302 — Surrogate Endpoint (SUR): Blood pressure
Study 17671042 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3187 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21813427 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 21813427 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 11378343 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 29910024 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29910024 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18713788 — Surrogate Endpoint (SUR): Bone mineral density
Study 30768224 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28576627 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23980056 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22109762 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 16415095 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8799095 — Surrogate Endpoint (SUR): Blood pressure
Study 31477280 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 9088584 — Surrogate Endpoint (SUR): Plasma ammonia
Study 31390907 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21724681 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21724681 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 21724681 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21724681 — Surrogate Endpoint (SUR): Blood pressure
Study 21724681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21724681 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20605316 — Surrogate Endpoint (SUR): Serum sodium
Study 11057103 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19853704 — Surrogate Endpoint (SUR): Serum creatinine
Study 10421972 — Surrogate Endpoint (SUR): Blood pressure
Study 2091171 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31810731 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 16449866 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25921849 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21224369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16868887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16868887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16868887 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26951352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23137503 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23137503 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31271585 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2920497 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23935129 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23935129 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 17196132 — Monitoring Biomarker (MOI): HBV DNA
Study 17196132 — Surrogate Endpoint (SUR): Serum creatinine
Study 15333417 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15333417 — Surrogate Endpoint (SUR): Blood pressure
Study 8388285 — Surrogate Endpoint (SUR): Blood pressure
Study 29576347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11032592 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22893497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22893497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10642363 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1380721 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31444036 — Predictive Biomarker (PRD): GLRB mRNA
Genes: GLRB
Study 26775268 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26775268 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 20200383 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 11836283 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31578073 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17094981 — Safety Biomarker (SAF): Interleukin 1
Study 17094981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17094981 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 26066736 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 19186958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11260410 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8045978 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8045978 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8045978 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 23615640 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 23615640 — Surrogate Endpoint (SUR): Blood pressure
Study 23615640 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23615640 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15513442 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 29420150 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 27716246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27716246 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 20691830 — Surrogate Endpoint (SUR): Blood pressure
Study 18240203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14673036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10069525 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 10069525 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 31359519 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31359519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18160686 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27041263 — Surrogate Endpoint (SUR): Blood pressure
Study 23715407 — Surrogate Endpoint (SUR): Blood pressure
Study 23221660 — Surrogate Endpoint (SUR): Blood pressure
Study 21374895 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9013219 — Surrogate Endpoint (SUR): Blood pressure
Study 8736043 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 26568566 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26568566 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 26568566 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 22115984 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22115984 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22115984 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 22115984 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 22115984 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22115984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22115984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19237716 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18070474 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 11560871 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11560871 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 27031165 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9892586 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 31704264 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31826005 — Surrogate Endpoint (SUR): Serum creatinine
Study 28060837 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28060837 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 28060837 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 20445533 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20445533 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18349171 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10574592 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10574592 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31492716 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15921933 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 28881355 — Predictive Biomarker (PRD): CTSL mRNA
Genes: CTSL; CTSL1
Study 28881355 — Predictive Biomarker (PRD): GSK3B mRNA
Genes: GSK3B
Study 28881355 — Predictive Biomarker (PRD): MED12 mRNA
Genes: MED12; ARC240; CAGH45; HOPA; KIAA0192; TNRC11; TRAP230
Study 28881355 — Predictive Biomarker (PRD): LAMC2 mRNA
Genes: LAMC2; LAMB2T; LAMNB2
Study 22307566 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17454195 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 10100275 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 25675650 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23306000 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19058332 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 29800784 — Surrogate Endpoint (SUR): Blood pressure
Study 18796517 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 18796517 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 18796517 — Surrogate Endpoint (SUR): Bone mineral density
Study 12866745 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 27377675 — Monitoring Biomarker (MOI): Procalcitonin
Study 31125079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31125079 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 31125079 — Surrogate Endpoint (SUR): Blood pressure
Study 29141858 — Safety Biomarker (SAF): Interleukin 1
Study 29141858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19926748 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22129522 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22129522 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6117392 — Surrogate Endpoint (SUR): Blood pressure
Study 31217962 — Surrogate Endpoint (SUR): Blood pressure
Study 20190646 — Surrogate Endpoint (SUR): Blood pressure
Study 10086330 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10086330 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 10086330 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10086330 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31952174 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23670958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29501386 — Surrogate Endpoint (SUR): Blood pressure
Study 25030039 — Surrogate Endpoint (SUR): Bone mineral density
Study 8722435 — Surrogate Endpoint (SUR): Blood pressure
Study 8722435 — Surrogate Endpoint (SUR): Serum triglycerides
Study 1888693 — Surrogate Endpoint (SUR): Blood pressure
Study 31043095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16389162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16389162 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16389162 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30209017 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 27387743 — Predictive Biomarker (PRD): Hormone receptor
Study 10401802 — Surrogate Endpoint (SUR): Blood pressure
Study 25407688 — Surrogate Endpoint (SUR): Blood pressure
Study 21353462 — Predictive Biomarker (PRD): AWAT2 mRNA
Genes: AWAT2; DC4; DGAT2L4; MFAT; WS
Study 19692317 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20118792 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20118792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15676092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25469804 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 25469804 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8246577 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8187026 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 8187026 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 6510453 — Surrogate Endpoint (SUR): Blood pressure
Study 27770155 — Surrogate Endpoint (SUR): Bone mineral density
Study 12510800 — Surrogate Endpoint (SUR): Bone mineral density
Study 9049514 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12873574 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29574075 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29574075 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21858807 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30768393 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 25727941 — Surrogate Endpoint (SUR): Blood pressure
Study 10612322 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10612322 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1647183 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1647183 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 27484801 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10543484 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8912225 — Surrogate Endpoint (SUR): Blood pressure
Study 19747623 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17210735 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 4041332 — Surrogate Endpoint (SUR): Blood pressure
Study 27974693 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15202794 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 2355813 — Surrogate Endpoint (SUR): Blood pressure
Study 16731290 — Surrogate Endpoint (SUR): Blood pressure
Study 3963032 — Surrogate Endpoint (SUR): Blood pressure
Study 27281061 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20175977 — Predictive Biomarker (PRD): TTMP mRNA
Genes: TTMP; C3orf52
Study 12524662 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 12524662 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12524662 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9031710 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10146939 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6835887 — Surrogate Endpoint (SUR): Blood pressure
Study 2005231 — Surrogate Endpoint (SUR): Bacterial count
Study 29910030 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29910030 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29910030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1