TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24201169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 24201169 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 24201169 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 17398194 — Surrogate Endpoint (SUR): Blood pressure
Study 17398194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17398194 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8722747 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1818543 — Surrogate Endpoint (SUR): Serum creatinine
Study 22415888 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 22415888 — Surrogate Endpoint (SUR): Blood pressure
Study 19855266 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 19855266 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7586113 — Surrogate Endpoint (SUR): Blood pressure
Study 24768112 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20455705 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20455705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17039265 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2146060 — Surrogate Endpoint (SUR): Blood pressure
Study 23635771 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 12001178 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 30053863 — Surrogate Endpoint (SUR): Blood pressure
Study 11022056 — Surrogate Endpoint (SUR): Blood pressure
Study 21289522 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9663178 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30720697 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26585940 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 24251363 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 24251363 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 18182665 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26875003 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25400472 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18397680 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 18397680 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 11879258 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19836995 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 17082240 — Surrogate Endpoint (SUR): Blood pressure
Study 17082240 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15021839 — Surrogate Endpoint (SUR): Blood pressure
Study 7924757 — Surrogate Endpoint (SUR): Blood pressure
Study 2867260 — Surrogate Endpoint (SUR): Blood pressure
Study 25692350 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20042475 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22049171 — Surrogate Endpoint (SUR): Blood pressure
Study 20464816 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 26919870 — Surrogate Endpoint (SUR): Blood pressure
Study 24060523 — Surrogate Endpoint (SUR): Blood pressure
Study 15766828 — Surrogate Endpoint (SUR): Blood pressure
Study 12183711 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21175981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21175981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21175981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15095806 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11407078 — Safety Biomarker (SAF): Hyaluronic acid
Study 9921004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9480464 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 9480464 — Predictive Biomarker (PRD): PIR mRNA
Genes: PIR
Study 9480464 — Surrogate Endpoint (SUR): Bone mineral density
Study 9480464 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30409085 — Surrogate Endpoint (SUR): Blood pressure
Study 30905230 — Safety Biomarker (SAF): Reactive oxygen species
Study 22101698 — Surrogate Endpoint (SUR): Bone mineral density
Study 11317194 — Surrogate Endpoint (SUR): Blood pressure
Study 3362176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3362176 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9231892 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9231892 — Surrogate Endpoint (SUR): Blood pressure
Study 30571562 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30571562 — Surrogate Endpoint (SUR): Serum creatinine
Study 25251676 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25251676 — Surrogate Endpoint (SUR): Blood pressure
Study 21164045 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 29463098 — Surrogate Endpoint (SUR): Blood pressure
Study 27064030 — Surrogate Endpoint (SUR): Blood pressure
Study 20521348 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16826020 — Surrogate Endpoint (SUR): Bone mineral density
Study 12792513 — Safety Biomarker (SAF): MTHFR
Study 6377884 — Surrogate Endpoint (SUR): Blood pressure
Study 24717919 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19158225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19158225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10979879 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23757126 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 18685605 — Surrogate Endpoint (SUR): Blood pressure
Study 30299473 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 30299473 — Safety Biomarker (SAF): Reactive oxygen species
Study 18366642 — Surrogate Endpoint (SUR): Blood pressure
Study 10573236 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 31771375 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 28679741 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 20674309 — Surrogate Endpoint (SUR): Blood pressure
Study 20674309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1100535 — Surrogate Endpoint (SUR): Blood pressure
Study 24084510 — Surrogate Endpoint (SUR): Blood pressure
Study 8603261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25237124 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 10069193 — Surrogate Endpoint (SUR): Serum creatinine
Study 10069193 — Surrogate Endpoint (SUR): Blood pressure
Study 29049868 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 25627090 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 25627090 — Predictive Biomarker (PRD): HTRA1 mRNA
Genes: HTRA1; HTRA; PRSS11
Study 2134545 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31729976 — Surrogate Endpoint (SUR): Blood pressure
Study 26441396 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 31868850 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 28012977 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 24285276 — Surrogate Endpoint (SUR): Bone mineral density
Study 14977339 — Surrogate Endpoint (SUR): Blood pressure
Study 10707788 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 29137895 — Predictive Biomarker (PRD): TMPRSS13 mRNA
Genes: TMPRSS13; MSP; TMPRSS11
Study 25517279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27327441 — Surrogate Endpoint (SUR): Blood pressure
Study 15931612 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15931612 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15931612 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7473798 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30373651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24850606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20669672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12859378 — Safety Biomarker (SAF): Hyaluronic acid
Study 26429522 — Surrogate Endpoint (SUR): Serum creatinine
Study 23052890 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 9894716 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31944250 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 30958348 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24393856 — Predictive Biomarker (PRD): RNF43 mRNA
Genes: RNF43
Study 24393856 — Predictive Biomarker (PRD): TOMM34 mRNA
Genes: TOMM34; URCC3
Study 24393856 — Predictive Biomarker (PRD): FOXM1 mRNA
Genes: FOXM1; FKHL16; HFH11; MPP2; WIN
Study 24393856 — Predictive Biomarker (PRD): MELK mRNA
Genes: MELK; KIAA0175
Study 24393856 — Predictive Biomarker (PRD): HJURP mRNA
Genes: HJURP; FAKTS; FLEG1; URLC9
Study 24393856 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 24393856 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 14557884 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 31802059 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31802059 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12231575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12231575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12231575 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 10090187 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 7581096 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24318688 — Surrogate Endpoint (SUR): Blood pressure
Study 21904901 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 17440020 — Surrogate Endpoint (SUR): Bone mineral density
Study 7983959 — Surrogate Endpoint (SUR): Blood pressure
Study 970902 — Surrogate Endpoint (SUR): Serum creatinine
Study 21388938 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 21388938 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21388938 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9198716 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8464952 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 31385000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31385000 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29255930 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 27060461 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 25292137 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22378727 — Predictive Biomarker (PRD): ABCG8 mRNA
Genes: ABCG8
Study 16422247 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19185633 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16733496 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 7955813 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 25675558 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 23754711 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8688261 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1840038 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1840038 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1840038 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 1840038 — Surrogate Endpoint (SUR): Blood pressure
Study 15821920 — Safety Biomarker (SAF): Hyaluronic acid
Study 28846563 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22311517 — Surrogate Endpoint (SUR): Serum calcium
Study 22311517 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12163427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12163427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12163427 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 12163427 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30153598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30153598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27427877 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17719303 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 17719303 — Surrogate Endpoint (SUR): Serum creatinine
Study 15212623 — Surrogate Endpoint (SUR): Bone mineral density
Study 9604941 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25171664 — Surrogate Endpoint (SUR): Blood pressure
Study 1510645 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6611245 — Surrogate Endpoint (SUR): Blood pressure
Study 28119757 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28119757 — Safety Biomarker (SAF): Reactive oxygen species
Study 20080470 — Safety Biomarker (SAF): Hyaluronic acid
Study 18595261 — Surrogate Endpoint (SUR): Blood pressure
Study 18595261 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11678968 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11678968 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7526753 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24998105 — Surrogate Endpoint (SUR): Blood pressure
Study 21494228 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21494228 — Surrogate Endpoint (SUR): Blood pressure
Study 18175740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14649310 — Surrogate Endpoint (SUR): Blood pressure
Study 26497857 — Predictive Biomarker (PRD): EHF mRNA
Genes: EHF; ESE3; ESE3B; ESEJ
Study 22834417 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17662759 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7562887 — Surrogate Endpoint (SUR): Blood pressure
Study 20236174 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19560968 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 22549509 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 22549509 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 11926786 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9074719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1680616 — Surrogate Endpoint (SUR): Serum potassium
Study 27267255 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 23965751 — Surrogate Endpoint (SUR): Urine free cortisol
Study 9573535 — Surrogate Endpoint (SUR): Blood pressure
Study 19478464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19478464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15536108 — Surrogate Endpoint (SUR): Blood pressure
Study 3118453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3118453 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31504461 — Predictive Biomarker (PRD): SIGLEC5 mRNA
Genes: SIGLEC5; CD33L2; OBBP2
Study 31504461 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 27533954 — Surrogate Endpoint (SUR): Blood pressure
Study 20947211 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 11329461 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26337521 — Predictive Biomarker (PRD): BNC1 mRNA
Genes: BNC1; BNC
Study 7610928 — Surrogate Endpoint (SUR): Bone mineral density
Study 8549036 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11776302 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 11776302 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8827777 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22513288 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22513288 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22513288 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20044806 — Monitoring Biomarker (MOI): HBV DNA
Study 28974553 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 21837450 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17470161 — Surrogate Endpoint (SUR): Bone mineral density
Study 7541235 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7541235 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26270693 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 10395845 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10395845 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 10395845 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 10395845 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 7477616 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7372824 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 23432528 — Surrogate Endpoint (SUR): Platelet count response
Study 21347869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21347869 — Monitoring Biomarker (MOI): Procalcitonin
Study 9040451 — Surrogate Endpoint (SUR): Blood pressure
Study 9040451 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7935657 — Surrogate Endpoint (SUR): Serum creatinine
Study 31706622 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 25773607 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25773607 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17161766 — Surrogate Endpoint (SUR): Blood pressure
Study 17161766 — Surrogate Endpoint (SUR): Serum potassium
Study 9187435 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 24504700 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 21989324 — Surrogate Endpoint (SUR): Blood pressure
Study 19942479 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19942479 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 12695416 — Surrogate Endpoint (SUR): Blood pressure
Study 10824628 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10824628 — Surrogate Endpoint (SUR): Blood pressure
Study 8870755 — Surrogate Endpoint (SUR): Blood pressure
Study 19177538 — Surrogate Endpoint (SUR): Bone mineral density
Study 7489530 — Surrogate Endpoint (SUR): Blood pressure
Study 30762267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30762267 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30762267 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17245230 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17245230 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17245230 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15911866 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7613151 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7613151 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7613151 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23480640 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8614309 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24332687 — Surrogate Endpoint (SUR): Blood pressure
Study 19726349 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16301340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2146996 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 24145207 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 19070440 — Surrogate Endpoint (SUR): Blood pressure
Study 27080156 — Surrogate Endpoint (SUR): Blood pressure