TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22127691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22127691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9291301 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29667496 — Surrogate Endpoint (SUR): Blood pressure
Study 27043671 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 27043671 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 27043671 — Surrogate Endpoint (SUR): Blood pressure
Study 15819388 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15819388 — Surrogate Endpoint (SUR): Blood pressure
Study 24008055 — Surrogate Endpoint (SUR): Blood pressure
Study 21549352 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 21792642 — Surrogate Endpoint (SUR): Blood pressure
Study 19278902 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 9690055 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30973970 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 21940785 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 17324239 — Safety Biomarker (SAF): Reactive oxygen species
Study 23591294 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 23591294 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23591294 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 10229291 — Surrogate Endpoint (SUR): Blood pressure
Study 6293712 — Surrogate Endpoint (SUR): Serum creatinine
Study 31409394 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 22989819 — Surrogate Endpoint (SUR): Blood pressure
Study 20589313 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20589313 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 28004415 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28004415 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25607117 — Surrogate Endpoint (SUR): Blood pressure
Study 21901395 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21901395 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 2439782 — Surrogate Endpoint (SUR): Blood pressure
Study 24944041 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20122630 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9106787 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30230266 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30230266 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23147875 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9700674 — Surrogate Endpoint (SUR): Blood pressure
Study 31714323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31714323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25540268 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16573800 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 2387667 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2387667 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28751226 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25199059 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 19526589 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 19526589 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 16493377 — Safety Biomarker (SAF): Reactive oxygen species
Study 31574087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31574087 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 31574087 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16478794 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 16478794 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 29066876 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25138579 — Surrogate Endpoint (SUR): Serum sodium
Study 9370179 — Surrogate Endpoint (SUR): Serum creatinine
Study 2877131 — Surrogate Endpoint (SUR): Serum testosterone
Study 25100892 — Surrogate Endpoint (SUR): Blood pressure
Study 22888676 — Surrogate Endpoint (SUR): Blood pressure
Study 19250082 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 2270581 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 28249614 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22275471 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 22275471 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 22275471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22275471 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11477461 — Surrogate Endpoint (SUR): Blood pressure
Study 9700713 — Surrogate Endpoint (SUR): Blood pressure
Study 2913770 — Surrogate Endpoint (SUR): Blood pressure
Study 2913770 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2913770 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26307616 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 346292 — Surrogate Endpoint (SUR): Blood pressure
Study 23358230 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 30840130 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29235300 — Surrogate Endpoint (SUR): Serum creatinine
Study 29235300 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 9620358 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9620358 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23596780 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 7945477 — Surrogate Endpoint (SUR): Serum creatinine
Study 29723220 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26216383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26216383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22218118 — Surrogate Endpoint (SUR): Serum creatinine
Study 21137665 — Predictive Biomarker (PRD): UROD mRNA
Genes: UROD
Study 21137665 — Surrogate Endpoint (SUR): Blood pressure
Study 2698748 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30866056 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 12151429 — Surrogate Endpoint (SUR): Serum testosterone
Study 16083511 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 25460033 — Surrogate Endpoint (SUR): Blood pressure
Study 21600005 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16685052 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15273083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11763409 — Surrogate Endpoint (SUR): Bone mineral density
Study 30150651 — Surrogate Endpoint (SUR): Blood pressure
Study 20680689 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 17889580 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 17277852 — Surrogate Endpoint (SUR): Blood pressure
Study 1355099 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 29907153 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 26979631 — Predictive Biomarker (PRD): PRKCA mRNA
Genes: PRKCA; PKCA; PRKACA
Study 26979631 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 26979631 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 26979631 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study 26979631 — Predictive Biomarker (PRD): IL16 mRNA
Genes: IL16
Study 26979631 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 26979631 — Predictive Biomarker (PRD): LIFR mRNA
Genes: LIFR
Study 26979631 — Safety Biomarker (SAF): IL16
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 22339485 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22339485 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16084150 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10565454 — Surrogate Endpoint (SUR): Bone mineral density
Study 1836422 — Surrogate Endpoint (SUR): Blood pressure
Study 7195247 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 23625541 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 12774471 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 27841047 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11576461 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9521254 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31618910 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 10221371 — Surrogate Endpoint (SUR): Blood pressure
Study 2145236 — Surrogate Endpoint (SUR): Blood pressure
Study 28853994 — Surrogate Endpoint (SUR): Blood pressure
Study 21856809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21856809 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17548664 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 15114031 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15114031 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 15114031 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 26102258 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24444439 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22967451 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22967451 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 22967451 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31954884 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 7137874 — Surrogate Endpoint (SUR): Blood pressure
Study 31182369 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 24438599 — Surrogate Endpoint (SUR): Blood pressure
Study 15138759 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 15138759 — Safety Biomarker (SAF): DRD2
Study 11266685 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 11266685 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25961456 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23514584 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 9205931 — Surrogate Endpoint (SUR): Blood pressure
Study 25643020 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 23721984 — Surrogate Endpoint (SUR): Blood pressure
Study 17044575 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 1425888 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 24852569 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 24852569 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 21856760 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29668860 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 25918184 — Surrogate Endpoint (SUR): Blood pressure
Study 18405147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2686956 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 497671 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 497671 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25403846 — Surrogate Endpoint (SUR): Bone mineral density
Study 24283768 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19411814 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17192117 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30597042 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 20074388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17038247 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17038247 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 8315799 — Surrogate Endpoint (SUR): Blood pressure
Study 20664906 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 20664906 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 1829439 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 6360178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30127374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30127374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24633366 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 2070512 — Surrogate Endpoint (SUR): Blood pressure
Study 6311774 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27333022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27333022 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27333022 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25103909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23095799 — Surrogate Endpoint (SUR): Blood pressure
Study 17681970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8599066 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24211400 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study 24211400 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 23494053 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 15994145 — Surrogate Endpoint (SUR): Serum creatinine
Study 11937566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11937566 — Safety Biomarker (SAF): IL-6 and IL-10
Study 11937566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 350248 — Surrogate Endpoint (SUR): Blood pressure
Study 9164223 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 7524907 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23756360 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23756360 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 23756360 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 20628233 — Surrogate Endpoint (SUR): Bone mineral density
Study 31588504 — Surrogate Endpoint (SUR): Blood pressure
Study 30473097 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27225316 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 18561718 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 14602752 — Surrogate Endpoint (SUR): Bone mineral density
Study 30381011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30381011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27694568 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21077775 — Surrogate Endpoint (SUR): Blood pressure
Study 3529351 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 29352461 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15452683 — Surrogate Endpoint (SUR): Blood pressure
Study 1838923 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1838923 — Surrogate Endpoint (SUR): Blood pressure
Study 25768849 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 16048250 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10073749 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 11679149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28460409 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27078269 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 18394567 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23941761 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 23941761 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 12824212 — Safety Biomarker (SAF): Preexisting antibody
Study 12212115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12212115 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1582788 — Surrogate Endpoint (SUR): Blood pressure
Study 4015065 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 4015065 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1441866 — Surrogate Endpoint (SUR): Blood pressure
Study 11564991 — Surrogate Endpoint (SUR): Blood pressure
Study 30720640 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24641624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 24641624 — Predictive Biomarker (PRD): ATF4 mRNA
Genes: ATF4; CREB2; TXREB
Study 16782174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16782174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15157691 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 7992902 — Surrogate Endpoint (SUR): Blood pressure
Study 18779378 — Surrogate Endpoint (SUR): Blood pressure
Study 18779378 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 29754651 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26880010 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 18395902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31488360 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 11837987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9522322 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 9522322 — Surrogate Endpoint (SUR): Bone mineral density
Study 25308804 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15610309 — Monitoring Biomarker (MOI): HBV DNA
Study 11502614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20473229 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20473229 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24508841 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 2673316 — Surrogate Endpoint (SUR): Blood pressure
Study 19174696 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17096684 — Surrogate Endpoint (SUR): Serum uric acid
Study 7781205 — Predictive Biomarker (PRD): AHSP mRNA
Genes: AHSP; EDRF; ERAF
Study 7781205 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 7781205 — Surrogate Endpoint (SUR): Blood pressure
Study 8525439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18835437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18835437 — Surrogate Endpoint (SUR): Blood pressure
Study 17920287 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15534166 — Surrogate Endpoint (SUR): Blood pressure
Study 2906897 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2906897 — Surrogate Endpoint (SUR): Blood pressure
Study 10916893 — Surrogate Endpoint (SUR): Blood pressure
Study 1569622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1569622 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1569622 — Surrogate Endpoint (SUR): Serum creatinine
Study 2868899 — Surrogate Endpoint (SUR): Blood pressure
Study 20642326 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12421891 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 31724170 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26588807 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19651803 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8968267 — Surrogate Endpoint (SUR): Blood pressure
Study 23864363 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 16175767 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 31262348 — Surrogate Endpoint (SUR): Blood pressure
Study 22402934 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22402934 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10529464 — Surrogate Endpoint (SUR): Bone mineral density
Study 10847421 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 11302109 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8363165 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8363165 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol