TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21540476 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 3207560 — Surrogate Endpoint (SUR): Blood pressure
Study 25811486 — Surrogate Endpoint (SUR): Blood pressure
Study 17239710 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 22928803 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 8467105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 3516092 — Surrogate Endpoint (SUR): Blood pressure
Study 31502387 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 25838311 — Surrogate Endpoint (SUR): Blood pressure
Study 25838311 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19126110 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15536601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9211442 — Predictive Biomarker (PRD): MPG mRNA
Genes: MPG; AAG; ANPG; MID1
Study 2527533 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30740640 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28619118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19298641 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19298641 — Surrogate Endpoint (SUR): Serum calcium
Study 12808136 — Safety Biomarker (SAF): Cytochrome c
Study 12174057 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 12174057 — Surrogate Endpoint (SUR): Serum testosterone
Study 22257645 — Surrogate Endpoint (SUR): Bone mineral density
Study 12002922 — Surrogate Endpoint (SUR): Serum creatinine
Study 8582105 — Surrogate Endpoint (SUR): Blood pressure
Study 15188323 — Surrogate Endpoint (SUR): Bone mineral density
Study 23217477 — Surrogate Endpoint (SUR): Blood pressure
Study 1403034 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23173249 — Surrogate Endpoint (SUR): Serum creatinine
Study 10444932 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 2340610 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6767648 — Surrogate Endpoint (SUR): Blood pressure
Study 24956415 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23422925 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 22027785 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 29797913 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 29797913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28169487 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 26062002 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20697940 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 15379418 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 7826821 — Surrogate Endpoint (SUR): Blood pressure
Study 3288172 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 15860712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15860712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9661647 — Surrogate Endpoint (SUR): Bone mineral density
Study 31254130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31254130 — Surrogate Endpoint (SUR): Serum calcium
Study 23142485 — Surrogate Endpoint (SUR): Blood pressure
Study 17147808 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 1418048 — Surrogate Endpoint (SUR): Blood pressure
Study 25440375 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25440375 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11916918 — Surrogate Endpoint (SUR): Blood pressure
Study 1540020 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 1540020 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 1540020 — Safety Biomarker (SAF): CDA
Genes: CDD
Study 30940833 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 11555157 — Predictive Biomarker (PRD): SERPINB3 mRNA
Genes: SERPINB3; SCCA; SCCA1
Study 30130297 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 30130297 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 28202745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28202745 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 6487508 — Surrogate Endpoint (SUR): Blood pressure
Study 6487508 — Surrogate Endpoint (SUR): Serum potassium
Study 25198487 — Surrogate Endpoint (SUR): Blood pressure
Study 6588267 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26493557 — Safety Biomarker (SAF): Hyaluronic acid
Study 24169335 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 24169335 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24169335 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 24169335 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 24169335 — Safety Biomarker (SAF): Reactive oxygen species
Study 16868892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16868892 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7957516 — Surrogate Endpoint (SUR): Blood pressure
Study 29634648 — Surrogate Endpoint (SUR): Blood pressure
Study 21457065 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11094664 — Surrogate Endpoint (SUR): Blood pressure
Study 25231836 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25231836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18777125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17152731 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 17152731 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8706769 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8706769 — Surrogate Endpoint (SUR): Blood pressure
Study 31426299 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31426299 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 31426299 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 26602073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3872304 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16956818 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 16956818 — Surrogate Endpoint (SUR): Bone mineral density
Study 10551639 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 24670086 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22803597 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10927737 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8723472 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2865712 — Surrogate Endpoint (SUR): Blood pressure
Study 21496417 — Surrogate Endpoint (SUR): Blood pressure
Study 16837676 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22372591 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20451681 — Safety Biomarker (SAF): Interleukin 1
Study 20451681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12477078 — Surrogate Endpoint (SUR): Blood pressure
Study 1575171 — Surrogate Endpoint (SUR): Blood pressure
Study 1575171 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27005470 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 25721344 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 15733808 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 10608469 — Surrogate Endpoint (SUR): Blood pressure
Study 7723358 — Surrogate Endpoint (SUR): Blood pressure
Study 8583466 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8583466 — Surrogate Endpoint (SUR): Blood pressure
Study 28116776 — Surrogate Endpoint (SUR): Blood pressure
Study 15167450 — Surrogate Endpoint (SUR): Blood pressure
Study 21689089 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8118749 — Surrogate Endpoint (SUR): Serum calcium
Study 30900008 — Surrogate Endpoint (SUR): Blood pressure
Study 18655472 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 17217711 — Surrogate Endpoint (SUR): Blood pressure
Study 17217711 — Surrogate Endpoint (SUR): Serum uric acid
Study 12662006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8097114 — Safety Biomarker (SAF): DRD2
Study 21365326 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 15827104 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 12905641 — Surrogate Endpoint (SUR): Bone mineral density
Study 9877516 — Surrogate Endpoint (SUR): Blood pressure
Study 9877516 — Surrogate Endpoint (SUR): Serum sodium
Study 9877516 — Surrogate Endpoint (SUR): Serum potassium
Study 2529370 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31813281 — Predictive Biomarker (PRD): MYH7 mRNA
Genes: MYH7; MYHCB
Study 23021320 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 11741108 — Surrogate Endpoint (SUR): Blood pressure
Study 9212953 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9212953 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9212953 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9212953 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8219660 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 8219660 — Surrogate Endpoint (SUR): Blood pressure
Study 8219660 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8219660 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2887475 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 29283450 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29283450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29283450 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26271931 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 1330962 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 16138560 — Surrogate Endpoint (SUR): Blood pressure
Study 16138560 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6294796 — Surrogate Endpoint (SUR): Serum creatinine
Study 17982122 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 17982122 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11549530 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8113548 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8113548 — Surrogate Endpoint (SUR): Blood pressure
Study 29231470 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26233501 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 27918846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25012265 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17886253 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28357504 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 21859401 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21859401 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19670623 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8083368 — Surrogate Endpoint (SUR): Blood pressure
Study 28859790 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16772251 — Surrogate Endpoint (SUR): Blood pressure
Study 15472496 — Surrogate Endpoint (SUR): Blood pressure
Study 15472496 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11379373 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 27716149 — Surrogate Endpoint (SUR): Serum creatinine
Study 14635294 — Surrogate Endpoint (SUR): Bone mineral density
Study 9093891 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9093891 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 18753076 — Surrogate Endpoint (SUR): Blood pressure
Study 15358623 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 15358623 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 12602461 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12602461 — Surrogate Endpoint (SUR): Blood pressure
Study 22001875 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24901723 — Surrogate Endpoint (SUR): Serum calcium
Study 31604477 — Surrogate Endpoint (SUR): Blood pressure
Study 22207322 — Safety Biomarker (SAF): Reactive oxygen species
Study 31314954 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 31314954 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 15138107 — Monitoring Biomarker (MOI): HBV DNA
Study 29903044 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 29903044 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 30863856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12059987 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 94637 — Surrogate Endpoint (SUR): Blood pressure
Study 18772180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18772180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7531732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15950141 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11821829 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30168613 — Predictive Biomarker (PRD): HOXA1 mRNA
Genes: HOXA1; HOX1F
Study 30168613 — Predictive Biomarker (PRD): EMX1 mRNA
Genes: EMX1
Study 30168613 — Predictive Biomarker (PRD): ECE1 mRNA
Genes: ECE1
Study 30168613 — Predictive Biomarker (PRD): PFKP mRNA
Genes: PFKP; PFKF
Study 30168613 — Predictive Biomarker (PRD): CLEC11A mRNA
Genes: CLEC11A; CLECSF3; LSLCL; SCGF
Study 30168613 — Predictive Biomarker (PRD): B3GALT6 mRNA
Genes: B3GALT6
Study 30168613 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 29849178 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20582464 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 18048574 — Surrogate Endpoint (SUR): Blood pressure
Study 18048574 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7757309 — Surrogate Endpoint (SUR): Blood pressure
Study 1554276 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31987248 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 12924540 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12924540 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10607690 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18581184 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11836010 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8573621 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 21756523 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8163252 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8163252 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11579696 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2687336 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2687336 — Surrogate Endpoint (SUR): Blood pressure
Study 31580707 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 19357529 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8573809 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23489186 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7854076 — Surrogate Endpoint (SUR): Blood pressure
Study 1826454 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26471194 — Surrogate Endpoint (SUR): Blood pressure
Study 9639376 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 9639376 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 9639376 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9639376 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9639376 — Surrogate Endpoint (SUR): Blood pressure
Study 30969032 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 21527360 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21527360 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10759711 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 27974398 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 11283429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11283429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9431285 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8507125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8507125 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20097702 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 20097702 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20097702 — Surrogate Endpoint (SUR): Blood pressure
Study 16162940 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1804644 — Surrogate Endpoint (SUR): Blood pressure
Study 27721230 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27721230 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27721230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25509696 — Surrogate Endpoint (SUR): Serum calcium
Study 18847425 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8255415 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23549522 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 21631324 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12477759 — Surrogate Endpoint (SUR): Blood pressure
Study 10951534 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 10951534 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 8858463 — Surrogate Endpoint (SUR): Serum creatinine
Study 8858463 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27357182 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27357182 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22628490 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 12165396 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7671361 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7671361 — Surrogate Endpoint (SUR): Blood pressure
Study 28476271 — Surrogate Endpoint (SUR): Blood pressure
Study 30715250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28715532 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 28715532 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 1691287 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20739720 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 15941534 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30690866 — Surrogate Endpoint (SUR): Blood pressure
Study 23104564 — Surrogate Endpoint (SUR): Serum calcium
Study 23104564 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 12505939 — Surrogate Endpoint (SUR): Blood pressure
Study 19567163 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 19567163 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 1980660 — Surrogate Endpoint (SUR): Blood pressure
Study 27935886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27935886 — Safety Biomarker (SAF): Interleukin 1
Study 27935886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27935886 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 107908 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 107908 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29735881 — Surrogate Endpoint (SUR): Blood pressure
Study 20678684 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2137653 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27283929 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 3289737 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28478985 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28478985 — Surrogate Endpoint (SUR): Probing pocket depth
Study 20601412 — Surrogate Endpoint (SUR): Serum testosterone
Study 10234582 — Surrogate Endpoint (SUR): Bone mineral density
Study 23910226 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 21989186 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 1683559 — Safety Biomarker (SAF): DRD2
Study 1683559 — Surrogate Endpoint (SUR): Blood pressure
Study 31475296 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19919396 — Surrogate Endpoint (SUR): Blood pressure
Study 16890574 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3