TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25999707 — Predictive Biomarker (PRD): EPHX1 mRNA
Genes: EPHX1; EPHX; EPOX
Study 23733779 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 19064840 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 12559680 — Surrogate Endpoint (SUR): Blood pressure
Study 12559680 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31352795 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 31352795 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27908347 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22402955 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19075279 — Predictive Biomarker (PRD): CLEC4D mRNA
Genes: CLEC4D; CLECSF8; MCL
Study 19075279 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12588354 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26519538 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 7589764 — Surrogate Endpoint (SUR): Blood pressure
Study 6971551 — Surrogate Endpoint (SUR): Serum calcium
Study 24112999 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 18065585 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1424409 — Surrogate Endpoint (SUR): Blood pressure
Study 22492697 — Predictive Biomarker (PRD): SHFL mRNA
Genes: SHFL; C19orf66; FLJ11286; IRAV; RYDEN; SFL
Study 1676251 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20682597 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 23932933 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22077933 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 17968381 — Surrogate Endpoint (SUR): Blood pressure
Study 17968381 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2148150 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31260565 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study 31260565 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 28708873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10858838 — Surrogate Endpoint (SUR): Blood pressure
Study 9350069 — Surrogate Endpoint (SUR): Blood pressure
Study 22453571 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22453571 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20041414 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20041414 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15816106 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10754618 — Surrogate Endpoint (SUR): Blood pressure
Study 6726012 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18663543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18663543 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16453051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11502782 — Surrogate Endpoint (SUR): Bone mineral density
Study 8124913 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 24231454 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 24231454 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 24231454 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24231454 — Predictive Biomarker (PRD): Microsatellite instability
Study 11305512 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 11305512 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 11305512 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 7898065 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7898065 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7898065 — Surrogate Endpoint (SUR): Blood pressure
Study 27485028 — Predictive Biomarker (PRD): PER1 mRNA
Genes: PER1; KIAA0482; PER; RIGUI
Study 27485028 — Predictive Biomarker (PRD): PER2 mRNA
Genes: PER2; KIAA0347
Study 27485028 — Predictive Biomarker (PRD): PER3 mRNA
Genes: PER3; GIG13
Study 24999075 — Surrogate Endpoint (SUR): Pathological complete response
Study 22651256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11742882 — Predictive Biomarker (PRD): SLC10A2 mRNA
Genes: SLC10A2; ASBT; ISBT; NTCP2
Study 27214600 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25271207 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 27760719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27760719 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23099972 — Surrogate Endpoint (SUR): Blood pressure
Study 17903693 — Surrogate Endpoint (SUR): Blood pressure
Study 10025832 — Surrogate Endpoint (SUR): Serum creatinine
Study 8862377 — Surrogate Endpoint (SUR): Blood pressure
Study 1606999 — Surrogate Endpoint (SUR): Blood pressure
Study 20685951 — Surrogate Endpoint (SUR): Blood pressure
Study 19066755 — Surrogate Endpoint (SUR): Bone mineral density
Study 16860894 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 16860894 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 12564610 — Safety Biomarker (SAF): DRD2
Study 3544689 — Surrogate Endpoint (SUR): Blood pressure
Study 29718556 — Surrogate Endpoint (SUR): Blood pressure
Study 27394191 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24456823 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 19268053 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3864227 — Surrogate Endpoint (SUR): Blood pressure
Study 7741287 — Surrogate Endpoint (SUR): Blood pressure
Study 28379486 — Surrogate Endpoint (SUR): Serum creatinine
Study 26485128 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 23408577 — Surrogate Endpoint (SUR): Bone mineral density
Study 17038641 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 23218961 — Predictive Biomarker (PRD): DSE mRNA
Genes: DSE; SART2
Study 18398080 — Surrogate Endpoint (SUR): Blood pressure
Study 18398080 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30508408 — Predictive Biomarker (PRD): SPG7 mRNA
Genes: SPG7; CAR; CMAR; PGN
Study 30508408 — Predictive Biomarker (PRD): ZFYVE26 mRNA
Genes: ZFYVE26; KIAA0321
Study 30796110 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 26125807 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26125807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26125807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26125807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9354343 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3006368 — Surrogate Endpoint (SUR): Blood pressure
Study 3006368 — Surrogate Endpoint (SUR): Serum triglycerides
Study 3006368 — Surrogate Endpoint (SUR): Serum sodium
Study 30139771 — Surrogate Endpoint (SUR): Blood pressure
Study 27193497 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 9667605 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study 2510253 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28235817 — Surrogate Endpoint (SUR): Blood pressure
Study 24436950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24436950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24436950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9772600 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22270487 — Surrogate Endpoint (SUR): Blood pressure
Study 19604523 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19604523 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15047004 — Surrogate Endpoint (SUR): Bone mineral density
Study 15047004 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 15047004 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9679526 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8024910 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28042685 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 7753573 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 7753573 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 7753573 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25519996 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24079282 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24079282 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17579892 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7696887 — Surrogate Endpoint (SUR): Bone mineral density
Study 22490197 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22490197 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9577947 — Surrogate Endpoint (SUR): Blood pressure
Study 26089677 — Surrogate Endpoint (SUR): Blood pressure
Study 19370040 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 3026273 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 3026273 — Surrogate Endpoint (SUR): Blood pressure
Study 11320359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9236502 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24060199 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19745564 — Surrogate Endpoint (SUR): Blood pressure
Study 11502787 — Surrogate Endpoint (SUR): Bone mineral density
Study 8484558 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 18399768 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 29739378 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15811479 — Surrogate Endpoint (SUR): Blood pressure
Study 15811479 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15811479 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15811479 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8974213 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14621733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26962396 — Safety Biomarker (SAF): Reactive oxygen species
Study 19817934 — Surrogate Endpoint (SUR): Blood pressure
Study 19817934 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17047290 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 7957349 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3310576 — Surrogate Endpoint (SUR): Blood pressure
Study 9395363 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3555585 — Surrogate Endpoint (SUR): Blood pressure
Study 31703750 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16413753 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12826020 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 25821315 — Safety Biomarker (SAF): Hyaluronic acid
Study 19767527 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 27014353 — Surrogate Endpoint (SUR): Blood pressure
Study 26843588 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 26843588 — Surrogate Endpoint (SUR): Blood pressure
Study 24789057 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 22447415 — Surrogate Endpoint (SUR): Serum sodium
Study 30641006 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 2279257 — Surrogate Endpoint (SUR): Blood pressure
Study 6775520 — Predictive Biomarker (PRD): FAM53B mRNA
Genes: FAM53B; KIAA0140; SMP
Study 19369667 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8484698 — Surrogate Endpoint (SUR): Bone mineral density
Study 28960914 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21464154 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 18210954 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8985850 — Surrogate Endpoint (SUR): Serum calcium
Study 31551229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31551229 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26818059 — Surrogate Endpoint (SUR): Blood pressure
Study 17015004 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 9829381 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20473880 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 20473880 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 20473880 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 28867267 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21944629 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 19857081 — Surrogate Endpoint (SUR): Blood pressure
Study 8147630 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28628970 — Surrogate Endpoint (SUR): Blood pressure
Study 28628970 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28628970 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28628970 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18972731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12717239 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1608680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24383431 — Surrogate Endpoint (SUR): Blood pressure
Study 24383431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20093665 — Surrogate Endpoint (SUR): Blood pressure
Study 16470490 — Surrogate Endpoint (SUR): Blood pressure
Study 7690383 — Surrogate Endpoint (SUR): Blood pressure
Study 29169968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29169968 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23453448 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23453448 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 23453448 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 23453448 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18347974 — Surrogate Endpoint (SUR): Blood pressure
Study 16418802 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16418802 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9052337 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8466349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12711121 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 8832309 — Surrogate Endpoint (SUR): Blood pressure
Study 24903207 — Surrogate Endpoint (SUR): Bone mineral density
Study 22420890 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 31278194 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31278194 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 17515857 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 16264051 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15563438 — Surrogate Endpoint (SUR): Bone mineral density
Study 28181363 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 8607723 — Surrogate Endpoint (SUR): Blood pressure
Study 8607723 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25163906 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 19648823 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19648823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17452676 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24988438 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 15613828 — Surrogate Endpoint (SUR): Blood pressure
Study 11691521 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 3436102 — Surrogate Endpoint (SUR): Blood pressure
Study 28341782 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 28341782 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28341782 — Surrogate Endpoint (SUR): Serum creatinine
Study 15116086 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10993625 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8843757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1346414 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24018711 — Surrogate Endpoint (SUR): Serum testosterone
Study 1632401 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25359382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23526739 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 23526739 — Predictive Biomarker (PRD): PAX3 mRNA
Genes: PAX3; HUP2
Study 23526739 — Predictive Biomarker (PRD): PAX7 mRNA
Genes: PAX7; HUP1
Study 17092365 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 10912846 — Surrogate Endpoint (SUR): Bone mineral density
Study 25923274 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23506314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23506314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16810109 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16571279 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16571279 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16571279 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7750187 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31417681 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 16638862 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29169011 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29169011 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26792822 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 22285278 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 14629852 — Surrogate Endpoint (SUR): Blood pressure
Study 14629852 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30634203 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30634203 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23996496 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23996496 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23996496 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 23996496 — Predictive Biomarker (PRD): NCAM1 mRNA
Genes: NCAM1; NCAM
Study 18677177 — Surrogate Endpoint (SUR): Blood pressure
Study 18677177 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18677177 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12182909 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12182909 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10469772 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1725549 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17906163 — Surrogate Endpoint (SUR): Blood pressure
Study 9451062 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7658056 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28830529 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25381858 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12882844 — Surrogate Endpoint (SUR): Blood pressure
Study 23185756 — Surrogate Endpoint (SUR): Serum creatinine
Study 16335686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7787918 — Surrogate Endpoint (SUR): Blood pressure
Study 21460356 — Surrogate Endpoint (SUR): Urinary oxalate
Study 23928094 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 23928094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23928094 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17545850 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9591926 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29748350 — Surrogate Endpoint (SUR): Serum creatinine
Study 28376921 — Surrogate Endpoint (SUR): Blood pressure
Study 28631250 — Surrogate Endpoint (SUR): Probing pocket depth
Study 20386463 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16051499 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 11518831 — Surrogate Endpoint (SUR): Bone mineral density
Study 7933659 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 30141180 — Surrogate Endpoint (SUR): Serum calcium
Study 25502081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27345158 — Surrogate Endpoint (SUR): Bone mineral density
Study 9251452 — Surrogate Endpoint (SUR): Serum creatinine
Study 17846548 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 28540893 — Surrogate Endpoint (SUR): Serum sodium