TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18408611 — Surrogate Endpoint (SUR): Blood pressure
Study 23569138 — Surrogate Endpoint (SUR): Serum creatinine
Study 23569138 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22173365 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22173365 — Surrogate Endpoint (SUR): Blood pressure
Study 14732723 — Surrogate Endpoint (SUR): Blood pressure
Study 11712625 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 31064847 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 29409143 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 29409143 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 25002832 — Surrogate Endpoint (SUR): Blood pressure
Study 8683249 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30883050 — Surrogate Endpoint (SUR): Blood pressure
Study 15172423 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 15172423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15172423 — Safety Biomarker (SAF): Reactive oxygen species
Study 20881001 — Predictive Biomarker (PRD): TPBG mRNA
Genes: TPBG; 5T4
Study 20881001 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30608390 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27296705 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24810181 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24810181 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10654204 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1858733 — Surrogate Endpoint (SUR): Serum calcium
Study 1858733 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 1858733 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 1858733 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29178024 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 8698440 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8698440 — Surrogate Endpoint (SUR): Blood pressure
Study 31707982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29411495 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26822582 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26822582 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26822582 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22301929 — Surrogate Endpoint (SUR): Blood pressure
Study 9569128 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 9569128 — Safety Biomarker (SAF): Reactive oxygen species
Study 28720715 — Surrogate Endpoint (SUR): Blood pressure
Study 19832818 — Predictive Biomarker (PRD): LNX1 mRNA
Genes: LNX1; LNX; PDZRN2; UNQ574/PRO1136
Study 2692332 — Surrogate Endpoint (SUR): Blood pressure
Study 2692332 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28446804 — Surrogate Endpoint (SUR): Blood pressure
Study 28446804 — Surrogate Endpoint (SUR): Serum uric acid
Study 30954969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20079220 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 14982911 — Surrogate Endpoint (SUR): Blood pressure
Study 8285181 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24553426 — Predictive Biomarker (PRD): ADH1B mRNA
Genes: ADH1B; ADH2
Study 17706223 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10585065 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 22781792 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 20193551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20193551 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11593916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18801781 — Surrogate Endpoint (SUR): Blood pressure
Study 17081623 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17081623 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17081623 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 14996484 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14996484 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9489643 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19935778 — Predictive Biomarker (PRD): KRT6A mRNA
Genes: KRT6A; K6A; KRT6D
Study 17397308 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study 7486603 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 30302786 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 24495792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24495792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24495792 — Surrogate Endpoint (SUR): Blood pressure
Study 24495792 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 17927554 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17927554 — Surrogate Endpoint (SUR): Blood pressure
Study 16371925 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 16371925 — Surrogate Endpoint (SUR): Serum creatinine
Study 23981400 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 21856226 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 21856226 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 9719164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9719164 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9719164 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2673623 — Surrogate Endpoint (SUR): Blood pressure
Study 1273208 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 31354513 — Surrogate Endpoint (SUR): Bone mineral density
Study 29020329 — Surrogate Endpoint (SUR): Bone mineral density
Study 20513595 — Surrogate Endpoint (SUR): Serum creatinine
Study 20513595 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18062901 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7614911 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 24549371 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331
Study 16336830 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 16336830 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11673584 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7948796 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3358596 — Surrogate Endpoint (SUR): Blood pressure
Study 28017787 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18936474 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18936474 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16476120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12897047 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10650326 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29080119 — Surrogate Endpoint (SUR): Serum creatinine
Study 24619763 — Surrogate Endpoint (SUR): Bone mineral density
Study 20707886 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7813254 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30286855 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19713152 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 12032117 — Surrogate Endpoint (SUR): Blood pressure
Study 9836078 — Surrogate Endpoint (SUR): Bone mineral density
Study 2591258 — Monitoring Biomarker (MOI): HBV DNA
Study 1098888 — Surrogate Endpoint (SUR): Blood pressure
Study 21606192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21606192 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21606192 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21606192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16948972 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 16948972 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16948972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9435196 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9435196 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21730216 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21730216 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 17341994 — Surrogate Endpoint (SUR): Blood pressure
Study 22308289 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18693743 — Safety Biomarker (SAF): Reactive oxygen species
Study 25567682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25567682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20570237 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16009446 — Surrogate Endpoint (SUR): Serum creatinine
Study 16009446 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12492585 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 21717516 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21717516 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21717516 — Surrogate Endpoint (SUR): Blood pressure
Study 17544845 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 17544845 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10553915 — Surrogate Endpoint (SUR): Blood pressure
Study 18205096 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18205096 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 28724309 — Surrogate Endpoint (SUR): Blood pressure
Study 9570426 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25633584 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 16531797 — Surrogate Endpoint (SUR): Blood pressure
Study 1412113 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24758075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18953863 — Monitoring Biomarker (MOI): HBV DNA
Study 12149106 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12149106 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7721636 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29117336 — Predictive Biomarker (PRD): TUBB2A mRNA
Genes: TUBB2A; TUBB2
Study 29117336 — Predictive Biomarker (PRD): CEP72 mRNA
Genes: CEP72; KIAA1519
Study 29117336 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 29117336 — Predictive Biomarker (PRD): GSK3B mRNA
Genes: GSK3B
Study 24432669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17166358 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8214944 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31115739 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31880807 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 17163237 — Surrogate Endpoint (SUR): Bone mineral density
Study 30496705 — Safety Biomarker (SAF): Reactive oxygen species
Study 28760225 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28760225 — Surrogate Endpoint (SUR): Blood pressure
Study 28760225 — Surrogate Endpoint (SUR): Serum creatinine
Study 20524999 — Surrogate Endpoint (SUR): Bone mineral density
Study 17768587 — Surrogate Endpoint (SUR): Bone mineral density
Study 16624969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 30387335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30387335 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30387335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30387335 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27339806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24365797 — Surrogate Endpoint (SUR): Blood pressure
Study 8534464 — Surrogate Endpoint (SUR): Blood pressure
Study 28479118 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 28479118 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21258206 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21258206 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 7879322 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 20002082 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16804951 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10807761 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10807761 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18584266 — Surrogate Endpoint (SUR): Blood pressure
Study 795441 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 12715722 — Safety Biomarker (SAF): Interleukin 1
Study 29795141 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12214263 — Surrogate Endpoint (SUR): Blood pressure
Study 8527266 — Surrogate Endpoint (SUR): Blood pressure
Study 25926562 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 6234335 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1686250 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 1686250 — Predictive Biomarker (PRD): PTK7 mRNA
Genes: PTK7; CCK4
Study 30453889 — Predictive Biomarker (PRD): MEST mRNA
Genes: MEST; PEG1
Study 18317375 — Predictive Biomarker (PRD): DDIT4 mRNA
Genes: DDIT4; REDD1; RTP801
Study 18317375 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 18317375 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 18317375 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 10862158 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9322569 — Surrogate Endpoint (SUR): Blood pressure
Study 18781853 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16755268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15307693 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15307693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15307693 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 15307693 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3080693 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27133819 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 22064737 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 8458057 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8458057 — Surrogate Endpoint (SUR): Blood pressure
Study 2957124 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 23801158 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21807330 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19027814 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 9476456 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9476456 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 3584738 — Surrogate Endpoint (SUR): Blood pressure
Study 10690940 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10690940 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7662242 — Surrogate Endpoint (SUR): Blood pressure
Study 31929469 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 17140398 — Surrogate Endpoint (SUR): Blood pressure
Study 16297751 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16297751 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16297751 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 16297751 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9719019 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7078717 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 31641767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26051874 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 16714852 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27490921 — Surrogate Endpoint (SUR): Blood pressure
Study 20199367 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12847071 — Surrogate Endpoint (SUR): Blood pressure
Study 11783243 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 25414593 — Surrogate Endpoint (SUR): Blood pressure
Study 14522414 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 14522414 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14522414 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14522414 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1623802 — Surrogate Endpoint (SUR): Serum potassium
Study 30007061 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 19450896 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 19450896 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 12228789 — Surrogate Endpoint (SUR): Blood pressure
Study 27010995 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 3658285 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3658285 — Surrogate Endpoint (SUR): Blood pressure
Study 27484224 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22494852 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21168619 — Surrogate Endpoint (SUR): Serum creatinine
Study 11040177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15753149 — Surrogate Endpoint (SUR): Blood pressure
Study 11728984 — Surrogate Endpoint (SUR): Serum creatinine
Study 27166718 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 16624686 — Surrogate Endpoint (SUR): Serum potassium
Study 16624686 — Surrogate Endpoint (SUR): Serum creatinine
Study 14661009 — Surrogate Endpoint (SUR): Blood pressure
Study 2124180 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 6153846 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27503905 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 27503905 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 7837215 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7837215 — Surrogate Endpoint (SUR): Blood pressure
Study 30738706 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26431662 — Monitoring Biomarker (MOI): HBV DNA
Study 23422375 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20700581 — Surrogate Endpoint (SUR): Bone mineral density
Study 15155117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12414877 — Surrogate Endpoint (SUR): Blood pressure
Study 12414877 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28675067 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 24844580 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 22019520 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 22019520 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8326288 — Surrogate Endpoint (SUR): Blood pressure
Study 2661065 — Surrogate Endpoint (SUR): Serum creatinine
Study 23322818 — Surrogate Endpoint (SUR): Bone mineral density
Study 19084935 — Monitoring Biomarker (MOI): HBV DNA
Study 16404492 — Surrogate Endpoint (SUR): Bone mineral density
Study 11244343 — Safety Biomarker (SAF): Hyaluronic acid
Study 9256118 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 12848770 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 10574604 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10574604 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 10574604 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 19855926 — Surrogate Endpoint (SUR): Bone mineral density