TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29959105 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 26999243 — Surrogate Endpoint (SUR): Blood pressure
Study 26999243 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10226770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10741622 — Surrogate Endpoint (SUR): Blood pressure
Study 9015467 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9015467 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1999932 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24931840 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 22735900 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10203111 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 21421179 — Surrogate Endpoint (SUR): Blood pressure
Study 18235907 — Surrogate Endpoint (SUR): Blood pressure
Study 24090685 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15974900 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8738693 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30859428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16680620 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 29921318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20033075 — Surrogate Endpoint (SUR): Blood pressure
Study 9465842 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 181978 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31200043 — Surrogate Endpoint (SUR): Blood pressure
Study 21489699 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 11063156 — Monitoring Biomarker (MOI): HBV DNA
Study 9067278 — Safety Biomarker (SAF): MTHFR
Study 21909151 — Surrogate Endpoint (SUR): Blood pressure
Study 16905783 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7964952 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 25539791 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 18455517 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 12717099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 31600365 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 26682789 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11943936 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7844609 — Safety Biomarker (SAF): Interleukin 1
Study 7844609 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7844609 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29324935 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 9605677 — Surrogate Endpoint (SUR): Blood pressure
Study 28993451 — Surrogate Endpoint (SUR): Blood pressure
Study 29067867 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 24461315 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 24461315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8577941 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9096189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9096189 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17664049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23524197 — Surrogate Endpoint (SUR): Blood pressure
Study 16894335 — Surrogate Endpoint (SUR): Blood pressure
Study 11702035 — Surrogate Endpoint (SUR): Blood pressure
Study 9143783 — Surrogate Endpoint (SUR): Blood pressure
Study 3597738 — Safety Biomarker (SAF): Hyaluronic acid
Study 19853417 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 9462474 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9462474 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 26460504 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 26460504 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26460504 — Surrogate Endpoint (SUR): Bone mineral density
Study 22739371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22739371 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22739371 — Surrogate Endpoint (SUR): Blood pressure
Study 22739371 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22739371 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 22226132 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 30846465 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 30846465 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26786346 — Surrogate Endpoint (SUR): Blood pressure
Study 11287373 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 2873966 — Surrogate Endpoint (SUR): Blood pressure
Study 12971634 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19147504 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17971178 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17971178 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28662296 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 26134371 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 12499335 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12499335 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11004144 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 31187045 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31187045 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28942334 — Surrogate Endpoint (SUR): Serum calcium
Study 26471432 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 26471432 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 26471432 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 23818758 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8373610 — Surrogate Endpoint (SUR): Blood pressure
Study 19670303 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9738734 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25715157 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23265571 — Surrogate Endpoint (SUR): Bone mineral density
Study 19833591 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19833591 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17560423 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 12590006 — Surrogate Endpoint (SUR): Bone mineral density
Study 11794823 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11794823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7992252 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7992252 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7992252 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7992252 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 4613531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 19106240 — Surrogate Endpoint (SUR): Blood pressure
Study 9647334 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9647334 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1825037 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16187243 — Surrogate Endpoint (SUR): Bone mineral density
Study 14508352 — Surrogate Endpoint (SUR): Serum creatinine
Study 31199595 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22440088 — Predictive Biomarker (PRD): MLLT3 mRNA
Genes: MLLT3; AF9; YEATS3
Study 22440088 — Predictive Biomarker (PRD): SGK1 mRNA
Genes: SGK1; SGK
Study 15637449 — Surrogate Endpoint (SUR): Blood pressure
Study 12359986 — Surrogate Endpoint (SUR): Blood pressure
Study 7954561 — Surrogate Endpoint (SUR): Blood pressure
Study 26714284 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 11502903 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 2442512 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2442512 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 2442512 — Surrogate Endpoint (SUR): Blood pressure
Study 28463904 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 19463375 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19463375 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 19463375 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19463375 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 19463375 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 14749149 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 10826396 — Surrogate Endpoint (SUR): Blood pressure
Study 29439704 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 11570617 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31585796 — Surrogate Endpoint (SUR): Blood pressure
Study 28095397 — Safety Biomarker (SAF): PPOX
Genes: HCRT; OX
Study 19996654 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19996654 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 19996654 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29396738 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 29396738 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 29396738 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 26603056 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19087842 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10069783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7584746 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23351578 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12106937 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2278365 — Surrogate Endpoint (SUR): Blood pressure
Study 17710561 — Surrogate Endpoint (SUR): Blood pressure
Study 22147075 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17382026 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15105062 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15105062 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18443351 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 12470424 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12470424 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7864411 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7864411 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7864411 — Surrogate Endpoint (SUR): Blood pressure
Study 6952022 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6952022 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28822046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26427563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20947593 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17636223 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 15553818 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15553818 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16206673 — Surrogate Endpoint (SUR): Blood pressure
Study 2544523 — Surrogate Endpoint (SUR): Blood pressure
Study 2544523 — Surrogate Endpoint (SUR): Serum creatinine
Study 29546692 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8335655 — Surrogate Endpoint (SUR): Blood pressure
Study 18696039 — Predictive Biomarker (PRD): MUC2 mRNA
Genes: MUC2; SMUC
Study 31076856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25104582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23082956 — Surrogate Endpoint (SUR): Blood pressure
Study 19681738 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17963431 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11449671 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9482129 — Surrogate Endpoint (SUR): Blood pressure
Study 8304488 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 25104262 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20507844 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18237592 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7586944 — Surrogate Endpoint (SUR): Blood pressure
Study 18927461 — Surrogate Endpoint (SUR): Blood pressure
Study 16600938 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 9264420 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27563680 — Surrogate Endpoint (SUR): Blood pressure
Study 22614285 — Safety Biomarker (SAF): Hyaluronic acid
Study 11752105 — Surrogate Endpoint (SUR): Blood pressure
Study 804397 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29037630 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 17188609 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 14767260 — Surrogate Endpoint (SUR): Blood pressure
Study 27682437 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 27682437 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21670470 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 21670470 — Predictive Biomarker (PRD): Chromosome 17p
Study 19751458 — Surrogate Endpoint (SUR): Blood pressure
Study 19751458 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7516637 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28432842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14731162 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30045185 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 12791810 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 11009288 — Surrogate Endpoint (SUR): Blood pressure
Study 7626347 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31343948 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31343948 — Surrogate Endpoint (SUR): Blood pressure
Study 23635846 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 22971323 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20795922 — Surrogate Endpoint (SUR): Blood pressure
Study 1676364 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6219403 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15470328 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9678535 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 9678535 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2648767 — Surrogate Endpoint (SUR): Blood pressure
Study 28542926 — Surrogate Endpoint (SUR): Blood pressure
Study 26698676 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 26698676 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 26698676 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24584875 — Predictive Biomarker (PRD): Hormone receptor
Study 20926027 — Surrogate Endpoint (SUR): Blood pressure
Study 10223249 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 30593693 — Predictive Biomarker (PRD): BMP2 mRNA
Genes: BMP2; BMP2A
Study 30593693 — Predictive Biomarker (PRD): BMP4 mRNA
Genes: BMP4; BMP2B; DVR4
Study 30593693 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 23692526 — Surrogate Endpoint (SUR): Blood pressure
Study 1921686 — Surrogate Endpoint (SUR): Blood pressure
Study 27707001 — Surrogate Endpoint (SUR): Blood pressure
Study 18564281 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18564281 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18564281 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31200945 — Surrogate Endpoint (SUR): Blood pressure
Study 25042896 — Surrogate Endpoint (SUR): Blood pressure
Study 22901550 — Surrogate Endpoint (SUR): Bone mineral density
Study 21104227 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 15509131 — Surrogate Endpoint (SUR): Blood pressure
Study 31272939 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31272939 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30227659 — Surrogate Endpoint (SUR): Blood pressure
Study 30227659 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30227659 — Surrogate Endpoint (SUR): Serum creatinine
Study 16278080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16278080 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 9536981 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9536981 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8021331 — Surrogate Endpoint (SUR): Blood pressure
Study 27999056 — Surrogate Endpoint (SUR): Bone mineral density
Study 7942325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7942325 — Safety Biomarker (SAF): Interleukin 1
Study 7942325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31046405 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 3143511 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 17592343 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19164351 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7589044 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7589044 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7589044 — Surrogate Endpoint (SUR): Blood pressure
Study 6124186 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 8816215 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 1487226 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2866672 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 30594222 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study 30594222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30594222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24840230 — Predictive Biomarker (PRD): Hormone receptor
Study 3539623 — Surrogate Endpoint (SUR): Blood pressure
Study 31168085 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20959555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15281970 — Surrogate Endpoint (SUR): Blood pressure
Study 11059636 — Surrogate Endpoint (SUR): Blood pressure
Study 18684855 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14685287 — Surrogate Endpoint (SUR): Blood pressure
Study 11910567 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11910567 — Surrogate Endpoint (SUR): Serum creatinine
Study 27029708 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27029708 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27029708 — Predictive Biomarker (PRD): Hormone receptor
Study 24423299 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24423299 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22753918 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22753918 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22753918 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 22753918 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 9232072 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2439783 — Surrogate Endpoint (SUR): Blood pressure
Study 25425539 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28447206 — Surrogate Endpoint (SUR): Serum uric acid
Study 28447206 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1