TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29285709 — Predictive Biomarker (PRD): NFKB2 mRNA
Genes: NFKB2; LYT10
Study 26797632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11952443 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9863864 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9863864 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 9863864 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8549944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25435217 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 25435217 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25435217 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23295056 — Monitoring Biomarker (MOI): HBV DNA
Study 21103669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21103669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18786751 — Predictive Biomarker (PRD): ATIC mRNA
Genes: ATIC; PURH; OK/SW-cl.86
Study 26910503 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17063156 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 16203281 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12018757 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 22106979 — Surrogate Endpoint (SUR): Blood pressure
Study 19424032 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 19424032 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 17545701 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9548602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9548602 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7753427 — Surrogate Endpoint (SUR): Blood pressure
Study 30607817 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30607817 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30607817 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 30607817 — Predictive Biomarker (PRD): Hormone receptor
Study 30934155 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22158143 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12119249 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6367690 — Surrogate Endpoint (SUR): Urine free cortisol
Study 26162946 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15975304 — Surrogate Endpoint (SUR): Serum creatinine
Study 15975304 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 15975304 — Surrogate Endpoint (SUR): Blood pressure
Study 19753721 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8614136 — Surrogate Endpoint (SUR): Serum creatinine
Study 27603344 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 24879492 — Surrogate Endpoint (SUR): Blood pressure
Study 9819017 — Surrogate Endpoint (SUR): Blood pressure
Study 7707420 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 7707420 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 2547410 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9432302 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 1549030 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 4025217 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 4025217 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27464321 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 22640930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22640930 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18235121 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 17027369 — Predictive Biomarker (PRD): GDF9 mRNA
Genes: GDF9
Study 15980352 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 10868525 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28283752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28283752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16156505 — Surrogate Endpoint (SUR): Blood pressure
Study 16156505 — Surrogate Endpoint (SUR): Serum creatinine
Study 11788414 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 11788414 — Surrogate Endpoint (SUR): Blood pressure
Study 7539609 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7539609 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25775165 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 8639180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8639180 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8639180 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 24658964 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24658964 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 17914132 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17914132 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7924164 — Surrogate Endpoint (SUR): Blood pressure
Study 9919621 — Safety Biomarker (SAF): Hypoxanthine-guanine phosphoribosyltransferase
Genes: HPRT1; HPRT
Study 31259734 — Predictive Biomarker (PRD): AKR1D1 mRNA
Genes: AKR1D1; SRD5B1
Study 31259734 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 21966999 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21966999 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 21966999 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23689561 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 20487528 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 10365534 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29573098 — Surrogate Endpoint (SUR): Blood pressure
Study 23018470 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23018470 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 23018470 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 17389151 — Surrogate Endpoint (SUR): Blood pressure
Study 1764941 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1764941 — Surrogate Endpoint (SUR): Blood pressure
Study 6299620 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17405568 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15618785 — Surrogate Endpoint (SUR): Blood pressure
Study 20707784 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 18517143 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 15851647 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10501817 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29500065 — Monitoring Biomarker (MOI): Cell-free DNA
Study 12147790 — Surrogate Endpoint (SUR): Blood pressure
Study 12147790 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9504938 — Surrogate Endpoint (SUR): Blood pressure
Study 9504938 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12576441 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 7199333 — Surrogate Endpoint (SUR): Blood pressure
Study 22466997 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 22466997 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 15964561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15964561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8740103 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6351455 — Surrogate Endpoint (SUR): Blood pressure
Study 6351455 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31522562 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 26861783 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26861783 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24717964 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22458741 — Surrogate Endpoint (SUR): Blood pressure
Study 6986949 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6986949 — Surrogate Endpoint (SUR): Blood pressure
Study 31647036 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2687423 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2687423 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31326727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31326727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27878354 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 16968405 — Safety Biomarker (SAF): Interleukin 12
Study 31829907 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31829907 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 31829907 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24468539 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8638784 — Surrogate Endpoint (SUR): Blood pressure
Study 31187518 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 12 beta
Genes: IL12B; NKSF2
Study 31187518 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 25886569 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16019923 — Predictive Biomarker (PRD): SH3PXD2A mRNA
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study 27854209 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study 18692637 — Surrogate Endpoint (SUR): Blood pressure
Study 14967869 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 14967869 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 11069375 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 4019261 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 31200819 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 27543984 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23356491 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 8473716 — Surrogate Endpoint (SUR): Blood pressure
Study 2951158 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28938434 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 17321924 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17321924 — Surrogate Endpoint (SUR): Blood pressure
Study 27826127 — Surrogate Endpoint (SUR): Bone mineral density
Study 26115878 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24033362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15919846 — Surrogate Endpoint (SUR): Blood pressure
Study 8970468 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16439498 — Surrogate Endpoint (SUR): Blood pressure
Study 7401203 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 6601746 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22055480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10340839 — Surrogate Endpoint (SUR): Blood pressure
Study 11324827 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11324827 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31927325 — Surrogate Endpoint (SUR): Blood pressure
Study 24503784 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10532693 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10532693 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6998274 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23149383 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 22218098 — Surrogate Endpoint (SUR): Blood pressure
Study 23011680 — Surrogate Endpoint (SUR): Bone mineral density
Study 2929629 — Surrogate Endpoint (SUR): Blood pressure
Study 29703040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20109208 — Surrogate Endpoint (SUR): Blood pressure
Study 15918622 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 12558577 — Predictive Biomarker (PRD): SULT1A3 mRNA
Genes: SULT1A3; STM
Study 9417493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29773717 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 29773717 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29773717 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 27416024 — Surrogate Endpoint (SUR): Serum creatinine
Study 27416024 — Surrogate Endpoint (SUR): Blood pressure
Study 18303470 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 10414911 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10414911 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8358504 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 29282929 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 18550935 — Surrogate Endpoint (SUR): Blood pressure
Study 1673587 — Surrogate Endpoint (SUR): Blood pressure
Study 30801699 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25070347 — Surrogate Endpoint (SUR): Blood pressure
Study 15066470 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7825744 — Safety Biomarker (SAF): Reactive oxygen species
Study 3240842 — Surrogate Endpoint (SUR): Blood pressure
Study 21908159 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12717397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12717397 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 12717397 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 8813840 — Surrogate Endpoint (SUR): Blood pressure
Study 1566165 — Surrogate Endpoint (SUR): Bone mineral density
Study 2547950 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2547950 — Surrogate Endpoint (SUR): Blood pressure
Study 26480553 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15279041 — Predictive Biomarker (PRD): TNR mRNA
Genes: TNR
Study 9003214 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8305125 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8305125 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8305125 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 22081005 — Surrogate Endpoint (SUR): Blood pressure
Study 20171410 — Predictive Biomarker (PRD): CBLC mRNA
Genes: CBLC; CBL3; RNF57
Study 18165396 — Surrogate Endpoint (SUR): Bone mineral density
Study 8140940 — Surrogate Endpoint (SUR): Bone mineral density
Study 28626213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29735470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21180368 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8628597 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 8628597 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8628597 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30048057 — Surrogate Endpoint (SUR): Bacterial count
Study 25277457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22368149 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 21142632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 216027 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31059955 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study 31059955 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 31059955 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 31059955 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 27893331 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27893331 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18931824 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 18931824 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18931824 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11060828 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21607954 — Predictive Biomarker (PRD): SLC15A1 mRNA
Genes: SLC15A1; PEPT1
Study 2853227 — Surrogate Endpoint (SUR): Blood pressure
Study 27605969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27605969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27605969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27605969 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21150554 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10702178 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 8397997 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12732401 — Surrogate Endpoint (SUR): Blood pressure
Study 19890262 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 18477227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7232842 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 17904975 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 9676035 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9676035 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 9676035 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30305054 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26248323 — Surrogate Endpoint (SUR): Blood pressure
Study 18496261 — Surrogate Endpoint (SUR): Blood pressure
Study 12713062 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26702629 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 17559725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17559725 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23024190 — Surrogate Endpoint (SUR): Bone mineral density
Study 25850975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25850975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25850975 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25850975 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19271112 — Monitoring Biomarker (MOI): HBV DNA
Study 17298711 — Surrogate Endpoint (SUR): Blood pressure
Study 10714841 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 30864824 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 18307373 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 17000242 — Surrogate Endpoint (SUR): Bone mineral density
Study 8948303 — Surrogate Endpoint (SUR): Blood pressure
Study 1746414 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1746414 — Surrogate Endpoint (SUR): Blood pressure
Study 21791142 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 19383589 — Surrogate Endpoint (SUR): Serum creatinine
Study 12492626 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12492626 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6193350 — Surrogate Endpoint (SUR): Blood pressure
Study 21833000 — Surrogate Endpoint (SUR): Blood pressure
Study 16946455 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10677399 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30371800 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26690356 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26690356 — Predictive Biomarker (PRD): SERPINF1 mRNA
Genes: SERPINF1; PEDF; PIG35
Study 20217128 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17351370 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17351370 — Surrogate Endpoint (SUR): Blood pressure