TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30018118 — Predictive Biomarker (PRD): CDX2 mRNA
Genes: CDX2; CDX3
Study 6986893 — Surrogate Endpoint (SUR): Blood pressure
Study 23375753 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31310919 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 25847553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25847553 — Surrogate Endpoint (SUR): Blood pressure
Study 23361504 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 23361504 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 9088589 — Surrogate Endpoint (SUR): Blood pressure
Study 8227803 — Surrogate Endpoint (SUR): Blood pressure
Study 3100446 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 14694037 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 3803413 — Surrogate Endpoint (SUR): Blood pressure
Study 30181085 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 30181085 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study 25464446 — Surrogate Endpoint (SUR): Blood pressure
Study 19774841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17469765 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17469765 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10030097 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8047525 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8047525 — Surrogate Endpoint (SUR): Blood pressure
Study 7865685 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7865685 — Surrogate Endpoint (SUR): Blood pressure
Study 7865685 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31784483 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 28137734 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 21104041 — Surrogate Endpoint (SUR): Blood pressure
Study 17126767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17126767 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11451296 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8918495 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6810904 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 24378016 — Surrogate Endpoint (SUR): Blood pressure
Study 21699447 — Surrogate Endpoint (SUR): Blood pressure
Study 12488649 — Surrogate Endpoint (SUR): Blood pressure
Study 27836866 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25861467 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 25861467 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15311169 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15311169 — Surrogate Endpoint (SUR): Blood pressure
Study 2952095 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 23252284 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23252284 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19336536 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15151614 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 25108889 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22412073 — Surrogate Endpoint (SUR): Blood pressure
Study 17386092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12138952 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12138952 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12138952 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28235526 — Surrogate Endpoint (SUR): Blood pressure
Study 26032587 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26032587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15147430 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 15147430 — Surrogate Endpoint (SUR): Blood pressure
Study 20126911 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10943869 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29798500 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 25009971 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18674411 — Surrogate Endpoint (SUR): Blood pressure
Study 30693979 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 30693979 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16198653 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 1787651 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 19947365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19947365 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17456483 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 31584063 — Surrogate Endpoint (SUR): Blood pressure
Study 31584063 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 31584063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19687522 — Surrogate Endpoint (SUR): Blood pressure
Study 11929022 — Predictive Biomarker (PRD): CMC2 mRNA
Genes: CMC2; C16orf61; DC13
Study 11929022 — Predictive Biomarker (PRD): CMC4 mRNA
Genes: CMC4; C6.1B; MTCP1; MTCP1NB
Study 19076110 — Surrogate Endpoint (SUR): Blood pressure
Study 15051744 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 31115462 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28291866 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15182772 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7905143 — Surrogate Endpoint (SUR): Blood pressure
Study 24674676 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24674676 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1974484 — Predictive Biomarker (PRD): ABL2 mRNA
Genes: ABL2; ABLL; ARG
Study 28447625 — Surrogate Endpoint (SUR): Blood pressure
Study 21777972 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12536495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3453385 — Surrogate Endpoint (SUR): Blood pressure
Study 22922591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19695390 — Surrogate Endpoint (SUR): Blood pressure
Study 11511139 — Surrogate Endpoint (SUR): Serum creatinine
Study 26739393 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25128203 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25128203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25128203 — Safety Biomarker (SAF): BDNF
Study 25128203 — Safety Biomarker (SAF): IL-6 and IL-10
Study 26526623 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 26526623 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26526623 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21399536 — Surrogate Endpoint (SUR): Blood pressure
Study 18097109 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1154272 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29225313 — Surrogate Endpoint (SUR): Blood pressure
Study 26514447 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26514447 — Safety Biomarker (SAF): BDNF
Study 22462558 — Surrogate Endpoint (SUR): Blood pressure
Study 10227808 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10227808 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 10227808 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24643636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24643636 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24643636 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 24643636 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12200521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28335893 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 1810018 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 6285503 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30730862 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23896791 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8005300 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 28368486 — Surrogate Endpoint (SUR): Serum testosterone
Study 24026893 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 24026893 — Surrogate Endpoint (SUR): Blood pressure
Study 21566104 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 12548298 — Surrogate Endpoint (SUR): Serum calcium
Study 25504080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12414334 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 10078679 — Surrogate Endpoint (SUR): Blood pressure
Study 24338139 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 332471 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 332471 — Surrogate Endpoint (SUR): Serum testosterone
Study 24195786 — Surrogate Endpoint (SUR): Blood pressure
Study 19957508 — Surrogate Endpoint (SUR): Blood pressure
Study 16886116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 27180949 — Surrogate Endpoint (SUR): Blood pressure
Study 1619181 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12783111 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12783111 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29869004 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 21117407 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10953902 — Surrogate Endpoint (SUR): Serum creatinine
Study 29634086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31512143 — Surrogate Endpoint (SUR): Blood pressure
Study 28223262 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 23662815 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 19473560 — Surrogate Endpoint (SUR): Blood pressure
Study 17636114 — Predictive Biomarker (PRD): SLC2A2 mRNA
Genes: SLC2A2; GLUT2
Study 17636114 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 12374678 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 12374678 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10075594 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10075594 — Surrogate Endpoint (SUR): Serum creatinine
Study 30951917 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 19763132 — Surrogate Endpoint (SUR): Blood pressure
Study 17088140 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11349183 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18608042 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12358335 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 7572651 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7572651 — Surrogate Endpoint (SUR): Blood pressure
Study 31797310 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 27415612 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27415612 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 22442826 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18508290 — Surrogate Endpoint (SUR): Serum sodium
Study 10979946 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8774389 — Surrogate Endpoint (SUR): Blood pressure
Study 12797909 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30310979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27386642 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27386642 — Monitoring Biomarker (MOI): HBV DNA
Study 22681643 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9729596 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24265819 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21943318 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 17136943 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10877734 — Surrogate Endpoint (SUR): Serum sodium
Study 20981001 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15701465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15701465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19560257 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 15001970 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15001970 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3544754 — Surrogate Endpoint (SUR): Blood pressure
Study 11156732 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 30871934 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 21940789 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2202247 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 25468506 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 22267336 — Predictive Biomarker (PRD): IGF2R mRNA
Genes: IGF2R; MPRI
Study 11813228 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31074115 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 23801589 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 325301 — Surrogate Endpoint (SUR): Blood pressure
Study 28056936 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 24692821 — Surrogate Endpoint (SUR): Blood pressure
Study 15670788 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 12765846 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 12765846 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10580781 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10580781 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10580781 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2366533 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 39387 — Surrogate Endpoint (SUR): Blood pressure
Study 20014653 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27039242 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 24683583 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24683583 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 1462581 — Surrogate Endpoint (SUR): Blood pressure
Study 25263326 — Surrogate Endpoint (SUR): Blood pressure
Study 9739036 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21084796 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 8912545 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31782408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31782408 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 31782408 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31782408 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31782408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31782408 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31782408 — Safety Biomarker (SAF): BDNF
Study 24732714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24732714 — Surrogate Endpoint (SUR): Blood pressure
Study 19608684 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 19608684 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 10798801 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10798801 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1676117 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16433247 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8546552 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6196821 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 6196821 — Predictive Biomarker (PRD): SPINK1 mRNA
Genes: SPINK1; PSTI
Study 25311633 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21038647 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 12140351 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12140351 — Surrogate Endpoint (SUR): Bone mineral density
Study 12140351 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22950654 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 18854568 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 8869864 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8869864 — Surrogate Endpoint (SUR): Blood pressure
Study 1504052 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30818032 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30818032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30818032 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30818032 — Safety Biomarker (SAF): IL-6 and IL-10
Study 29324303 — Predictive Biomarker (PRD): Hormone receptor
Study 27871510 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 27871510 — Surrogate Endpoint (SUR): Blood pressure
Study 19852540 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 18395326 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 16164192 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 16164192 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 16164192 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 12749519 — Surrogate Endpoint (SUR): Blood pressure
Study 26758039 — Surrogate Endpoint (SUR): Serum creatinine
Study 7776913 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27066188 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 27066188 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 27066188 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17996511 — Surrogate Endpoint (SUR): Blood pressure
Study 15743365 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7174 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25156269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25156269 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21842996 — Surrogate Endpoint (SUR): Blood pressure
Study 1909152 — Surrogate Endpoint (SUR): Blood pressure
Study 31132509 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 23713294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23713294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23713294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21606263 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 15042546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15042546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15042546 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15042546 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15042546 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19531591 — Surrogate Endpoint (SUR): Bone mineral density
Study 28940312 — Predictive Biomarker (PRD): TRIM32 mRNA
Genes: TRIM32; HT2A
Study 10857970 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 9120161 — Safety Biomarker (SAF): Cytochrome c
Study 26762911 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 29584458 — Surrogate Endpoint (SUR): Blood pressure
Study 23220077 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17018708 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16326641 — Predictive Biomarker (PRD): PALM mRNA
Genes: PALM; KIAA0270
Study 7597662 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE