TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22397239 — Surrogate Endpoint (SUR): Serum creatinine
Study 22397239 — Surrogate Endpoint (SUR): Blood pressure
Study 18583434 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 17509426 — Surrogate Endpoint (SUR): Serum creatinine
Study 4012373 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 4012373 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26043562 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18226669 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23735352 — Surrogate Endpoint (SUR): Serum creatinine
Study 8712143 — Surrogate Endpoint (SUR): Blood pressure
Study 1940058 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1940058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31683226 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31683226 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31683226 — Surrogate Endpoint (SUR): Blood pressure
Study 25361552 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 21733742 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 16393881 — Predictive Biomarker (PRD): KCNN3 mRNA
Genes: KCNN3; K3
Study 2223334 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 31148473 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12411537 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9283064 — Surrogate Endpoint (SUR): Blood pressure
Study 30111065 — Monitoring Biomarker (MOI): Procalcitonin
Study 24833354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22452610 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22452610 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22452610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20505271 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17594199 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7587726 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6763456 — Surrogate Endpoint (SUR): Blood pressure
Study 26293358 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19755409 — Surrogate Endpoint (SUR): Blood pressure
Study 28052014 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28052014 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18494605 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18494605 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12690946 — Surrogate Endpoint (SUR): Blood pressure
Study 30096932 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 30096932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30096932 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 30096932 — Safety Biomarker (SAF): BDNF
Study 12410456 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27672124 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23968157 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 23968157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23968157 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19142656 — Surrogate Endpoint (SUR): Blood pressure
Study 16489526 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15094102 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3046814 — Surrogate Endpoint (SUR): Blood pressure
Study 3046814 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29701288 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 29701288 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29701288 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 29701288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29498050 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19053917 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 29370829 — Surrogate Endpoint (SUR): Blood pressure
Study 17559147 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11955464 — Surrogate Endpoint (SUR): Blood pressure
Study 1555273 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15741443 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10916110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10916110 — Safety Biomarker (SAF): MTHFR
Study 8873685 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8873685 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30183743 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 30183743 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12795776 — Surrogate Endpoint (SUR): Serum potassium
Study 12795776 — Surrogate Endpoint (SUR): Blood pressure
Study 29858504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29858504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29858504 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29858504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20663148 — Surrogate Endpoint (SUR): Blood pressure
Study 20663148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17135583 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1418170 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26328056 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 21747102 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29570121 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 26656911 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 26656911 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 26656911 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 22243938 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 22243938 — Safety Biomarker (SAF): Sodium/hydrogen exchanger 3
Genes: SLC9A3; NHE3
Study 22243938 — Surrogate Endpoint (SUR): Serum creatinine
Study 22243938 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21425566 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22248760 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21333426 — Surrogate Endpoint (SUR): Total kidney volume
Study 21333426 — Surrogate Endpoint (SUR): Blood pressure
Study 17298975 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 31242924 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 31242924 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 21459791 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16776928 — Surrogate Endpoint (SUR): Blood pressure
Study 10856535 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9021345 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 9021345 — Surrogate Endpoint (SUR): Blood pressure
Study 3882735 — Surrogate Endpoint (SUR): Blood pressure
Study 28891027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20798191 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12906185 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 12906185 — Predictive Biomarker (PRD): TET1 mRNA
Genes: TET1; CXXC6; KIAA1676; LCX
Study 12452216 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12452216 — Surrogate Endpoint (SUR): Blood pressure
Study 7732154 — Surrogate Endpoint (SUR): Blood pressure
Study 24518937 — Surrogate Endpoint (SUR): Blood pressure
Study 22028408 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 19791552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9333168 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28526377 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28526377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19182698 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12453926 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30648358 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 18483232 — Surrogate Endpoint (SUR): Serum creatinine
Study 16943537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14502085 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11300369 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8982289 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8982289 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8982289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30575407 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 30575407 — Predictive Biomarker (PRD): CYBC1 mRNA
Genes: CYBC1; C17orf62; EROS
Study 26842771 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17971261 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 16896685 — Predictive Biomarker (PRD): PISD mRNA
Genes: PISD
Study 2856778 — Surrogate Endpoint (SUR): Blood pressure
Study 30059989 — Predictive Biomarker (PRD): IL27
Genes: IL-27; p28; IL27p28; IL-27A; IL27A; MGC71873
Study 24414607 — Surrogate Endpoint (SUR): Bone mineral density
Study 19752398 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study 10601507 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12407781 — Surrogate Endpoint (SUR): Blood pressure
Study 23000025 — Surrogate Endpoint (SUR): Blood pressure
Study 26301648 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19293358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10437265 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 10437265 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27748721 — Predictive Biomarker (PRD): RRM2 mRNA
Genes: RRM2; RR2
Study 27748721 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 12454842 — Monitoring Biomarker (MOI): HBV DNA
Study 10508813 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7582300 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 29752008 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 21533812 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 31552779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31552779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31552779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25496446 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 25496446 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 11429349 — Surrogate Endpoint (SUR): Blood pressure
Study 2848053 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2848053 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 22831853 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 22333618 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11103184 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11103184 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3954442 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21881597 — Surrogate Endpoint (SUR): Blood pressure
Study 20708076 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8391756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8391756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26571012 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27929530 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 18719760 — Surrogate Endpoint (SUR): Blood pressure
Study 24026142 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24026142 — Surrogate Endpoint (SUR): Blood pressure
Study 8571194 — Surrogate Endpoint (SUR): Blood pressure
Study 6886033 — Surrogate Endpoint (SUR): Serum calcium
Study 31797473 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 31797473 — Predictive Biomarker (PRD): OLR1 mRNA
Genes: OLR1; CLEC8A; LOX1
Study 31797473 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 31797473 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27693003 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27693003 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 27693003 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 27693003 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 23113833 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 23113833 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18845960 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 18845960 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 18845960 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 18845960 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 12621013 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 1462984 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30640988 — Safety Biomarker (SAF): Reactive oxygen species
Study 30371759 — Surrogate Endpoint (SUR): Blood pressure
Study 29846606 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 3307307 — Surrogate Endpoint (SUR): Blood pressure
Study 27029960 — Surrogate Endpoint (SUR): Blood pressure
Study 25564396 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 25739904 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24517060 — Safety Biomarker (SAF): Urinary total protein
Study 16963658 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 3654034 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 31724349 — Surrogate Endpoint (SUR): Blood pressure
Study 22101876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22101876 — Surrogate Endpoint (SUR): Blood pressure
Study 9631802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7874838 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31366977 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 25948208 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 25948208 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25948208 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17069814 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 28382618 — Surrogate Endpoint (SUR): Bone mineral density
Study 23647281 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16482646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16948927 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 16948927 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 14503797 — Predictive Biomarker (PRD): Hormone receptor
Study 10895224 — Surrogate Endpoint (SUR): Blood pressure
Study 28432157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28432157 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28432157 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20690864 — Safety Biomarker (SAF): Hyaluronic acid
Study 15315625 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 9076589 — Surrogate Endpoint (SUR): Bone mineral density
Study 30478089 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22334769 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26659384 — Surrogate Endpoint (SUR): Blood pressure
Study 25149384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23129602 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 23129602 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6374931 — Surrogate Endpoint (SUR): Blood pressure
Study 28046032 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28046032 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 23469685 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 23469685 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 23469685 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23469685 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 23469685 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 10912746 — Surrogate Endpoint (SUR): Blood pressure
Study 22699418 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 22699418 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 9988803 — Surrogate Endpoint (SUR): Blood pressure
Study 17926612 — Surrogate Endpoint (SUR): Blood pressure
Study 15178812 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15178812 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20446945 — Surrogate Endpoint (SUR): Blood pressure
Study 21392096 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21392096 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15126524 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26252751 — Surrogate Endpoint (SUR): Bacterial count
Study 20886231 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9088654 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11044464 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 24423366 — Surrogate Endpoint (SUR): Bone mineral density
Study 23301470 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23301470 — Safety Biomarker (SAF): Interleukin 12
Study 7529522 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 7529522 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 727423 — Surrogate Endpoint (SUR): Blood pressure
Study 26525549 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26525549 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26525549 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 24225205 — Predictive Biomarker (PRD): NR4A1 mRNA
Genes: NR4A1; GFRP1; HMR; NAK1
Study 10790574 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7755939 — Surrogate Endpoint (SUR): Blood pressure
Study 26158441 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26158441 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26158441 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 9314427 — Surrogate Endpoint (SUR): Blood pressure
Study 3524465 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 3524465 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 20675691 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 20675691 — Safety Biomarker (SAF): Hyaluronic acid
Study 20675691 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 15761945 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22187590 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 29474712 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 29474712 — Surrogate Endpoint (SUR): Blood pressure
Study 24229565 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20131262 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17