TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1310464 — Surrogate Endpoint (SUR): Blood pressure
Study 21570271 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19634546 — Surrogate Endpoint (SUR): Blood pressure
Study 10856732 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29027352 — Surrogate Endpoint (SUR): Serum creatinine
Study 25702786 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 25702786 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 25702786 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 25702786 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 24737923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12584671 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12584671 — Surrogate Endpoint (SUR): Blood pressure
Study 1975189 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1975189 — Surrogate Endpoint (SUR): Blood pressure
Study 28374907 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 17804673 — Surrogate Endpoint (SUR): Blood pressure
Study 12667363 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 12667363 — Surrogate Endpoint (SUR): Bone mineral density
Study 12667363 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 7818118 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7818118 — Surrogate Endpoint (SUR): Blood pressure
Study 28446631 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28446631 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 6084754 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 6084754 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 26654244 — Surrogate Endpoint (SUR): Blood pressure
Study 20820148 — Surrogate Endpoint (SUR): Serum creatinine
Study 17085378 — Surrogate Endpoint (SUR): Blood pressure
Study 17085378 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10805047 — Surrogate Endpoint (SUR): Blood pressure
Study 30613964 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16271337 — Predictive Biomarker (PRD): FBL mRNA
Genes: FBL; FIB1; FLRN
Study 20393508 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 19673331 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16840747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11273875 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 3057832 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30883000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7838921 — Surrogate Endpoint (SUR): Blood pressure
Study 3414514 — Surrogate Endpoint (SUR): Blood pressure
Study 16360267 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 8937798 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17916662 — Safety Biomarker (SAF): Reactive oxygen species
Study 17916662 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8619011 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 29131124 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 21248398 — Safety Biomarker (SAF): Hyaluronic acid
Study 10731735 — Surrogate Endpoint (SUR): Serum creatinine
Study 30582447 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23356124 — Surrogate Endpoint (SUR): Blood pressure
Study 22042366 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22042366 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 20381283 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20381283 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 18060244 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12766123 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29551346 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24509697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28011809 — Surrogate Endpoint (SUR): Bone mineral density
Study 24961753 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 24961753 — Surrogate Endpoint (SUR): Blood pressure
Study 21983371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21983371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21983371 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19578220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11314833 — Surrogate Endpoint (SUR): Blood pressure
Study 28228162 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 28228162 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 21068346 — Surrogate Endpoint (SUR): Blood pressure
Study 28810 — Surrogate Endpoint (SUR): Blood pressure
Study 31542876 — Predictive Biomarker (PRD): Hormone receptor
Study 26103654 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 15138475 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 17339189 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17339189 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11295361 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 25935793 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25935793 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16337368 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 19118910 — Surrogate Endpoint (SUR): Blood pressure
Study 17727860 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14646367 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14646367 — Surrogate Endpoint (SUR): Serum creatinine
Study 25306677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25306677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25306677 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 25306677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24748338 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23735004 — Surrogate Endpoint (SUR): Blood pressure
Study 23735004 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23735004 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17133193 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9024265 — Surrogate Endpoint (SUR): Bone mineral density
Study 30712954 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 20972900 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17950795 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17242663 — Predictive Biomarker (PRD): Chromosome 5q
Study 10804778 — Surrogate Endpoint (SUR): Blood pressure
Study 30898204 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30898204 — Surrogate Endpoint (SUR): Serum testosterone
Study 1418836 — Surrogate Endpoint (SUR): Blood pressure
Study 30004900 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26976418 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16359503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16359503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9551874 — Surrogate Endpoint (SUR): Blood pressure
Study 29311763 — Surrogate Endpoint (SUR): Blood pressure
Study 30415610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30415610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25900168 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 25900168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25900168 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21450597 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 11960657 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 28199814 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 28199814 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 28199814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28199814 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19349290 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20075530 — Surrogate Endpoint (SUR): Blood pressure
Study 2144018 — Safety Biomarker (SAF): XRCC1
Genes: RCC
Study 27616331 — Surrogate Endpoint (SUR): Blood pressure
Study 26453532 — Surrogate Endpoint (SUR): Blood pressure
Study 25128296 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 21905981 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1618244 — Surrogate Endpoint (SUR): Blood pressure
Study 23992160 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 14551370 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 9409567 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2442558 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2442558 — Surrogate Endpoint (SUR): Blood pressure
Study 27099270 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 22503720 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22503720 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 2891798 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 28473464 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 16683215 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16683215 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11467090 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7833222 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17171860 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28258664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28258664 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28258664 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25486333 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 10949722 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 8766611 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17541072 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 31653603 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 23589556 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23589556 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19581850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19581850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12098150 — Predictive Biomarker (PRD): SERPINB6 mRNA
Genes: SERPINB6; PI6; PTI
Study 10023509 — Surrogate Endpoint (SUR): Blood pressure
Study 29982770 — Surrogate Endpoint (SUR): Blood pressure
Study 25671826 — Monitoring Biomarker (MOI): HBV DNA
Study 17722824 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30480533 — Surrogate Endpoint (SUR): Blood pressure
Study 18176118 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30084882 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8476620 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22710649 — Surrogate Endpoint (SUR): Blood pressure
Study 19748210 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10600919 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 1771945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27566855 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17221036 — Surrogate Endpoint (SUR): Blood pressure
Study 26849923 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23681364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23681364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1886157 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 6229567 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 19497197 — Monitoring Biomarker (MOI): HBV DNA
Study 7541448 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2473880 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 19573556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19573556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17380560 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 14679114 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19719910 — Monitoring Biomarker (MOI): HBV DNA
Study 12223140 — Monitoring Biomarker (MOI): HBV DNA
Study 11557486 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31924955 — Surrogate Endpoint (SUR): Blood pressure
Study 31924955 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25620034 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17403707 — Surrogate Endpoint (SUR): Blood pressure
Study 14978366 — Surrogate Endpoint (SUR): Blood pressure
Study 2503945 — Surrogate Endpoint (SUR): Blood pressure
Study 30995312 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26066063 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26066063 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23862647 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 21209124 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 18305082 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18305082 — Surrogate Endpoint (SUR): Serum creatinine
Study 18305082 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18305082 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12207105 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 26471311 — Surrogate Endpoint (SUR): Serum calcium
Study 12964946 — Surrogate Endpoint (SUR): Blood pressure
Study 27855097 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 29343076 — Surrogate Endpoint (SUR): Serum creatinine
Study 29343076 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 22351696 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15237710 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 15237710 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 9862573 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21635359 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15194910 — Surrogate Endpoint (SUR): Blood pressure
Study 11897984 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11897984 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17717132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15039514 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22406074 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 28057126 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 28057126 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21574984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12698776 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29155861 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29155861 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9059545 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 9059545 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 9059545 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16331118 — Surrogate Endpoint (SUR): Blood pressure
Study 1281442 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17179910 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 9797644 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 22607734 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 21851643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21851643 — Surrogate Endpoint (SUR): Blood pressure
Study 19148642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19148642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17214932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17214932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17214932 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 17214932 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24595568 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 24595568 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 24595568 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 30407328 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12957433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8862762 — Surrogate Endpoint (SUR): Serum calcium
Study 1340807 — Surrogate Endpoint (SUR): Blood pressure
Study 17577134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17577134 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17577134 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11880130 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 2277574 — Surrogate Endpoint (SUR): Serum potassium
Study 21489817 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15033254 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29118031 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29118031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21636566 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21636566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21636566 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 10651259 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 31421670 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 31421670 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 27893184 — Predictive Biomarker (PRD): CACNA1C mRNA
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 23880960 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 17967584 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17967584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25817289 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 25817289 — Surrogate Endpoint (SUR): Blood pressure
Study 22082795 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22082795 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 22695134 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18946298 — Surrogate Endpoint (SUR): Blood pressure
Study 12824967 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11938811 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 11938811 — Surrogate Endpoint (SUR): Blood pressure
Study 29242281 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29242281 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 25522424 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25522424 — Safety Biomarker (SAF): BDNF