TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23766359 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23766359 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 7930281 — Surrogate Endpoint (SUR): Blood pressure
Study 1219183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 7399873 — Surrogate Endpoint (SUR): Blood pressure
Study 2297191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25978169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25978169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25978169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19526798 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15033608 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11597289 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31910748 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30793412 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 25827693 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16792582 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 8231903 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26905919 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12021741 — Surrogate Endpoint (SUR): Blood pressure
Study 8651088 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26930415 — Predictive Biomarker (PRD): RHOF mRNA
Genes: RHOF; ARHF; RIF
Study 8527349 — Surrogate Endpoint (SUR): Blood pressure
Study 27548072 — Surrogate Endpoint (SUR): Blood pressure
Study 19238125 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 11765145 — Surrogate Endpoint (SUR): Blood pressure
Study 25342703 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26109009 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26109009 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17292646 — Surrogate Endpoint (SUR): Serum potassium
Study 7798653 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 397016 — Surrogate Endpoint (SUR): Blood pressure
Study 28984580 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21484237 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19057376 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9499204 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9499204 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 3207438 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 29336700 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20435447 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 16611657 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16611657 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1550435 — Surrogate Endpoint (SUR): Blood pressure
Study 12953127 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27869410 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 17868007 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9030805 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8391064 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 23453352 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28245352 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28245352 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 24681963 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 16231263 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2007851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2007851 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23129778 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23129778 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 15531034 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11417762 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9792572 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 24334183 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 21094802 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 21094802 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 21094802 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21094802 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21094802 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 10607766 — Surrogate Endpoint (SUR): Serum creatinine
Study 9193328 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3702764 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 3702764 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29987678 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 12039127 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12039127 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12039127 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 3293479 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3293479 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 26853137 — Surrogate Endpoint (SUR): Blood pressure
Study 20413122 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20413122 — Surrogate Endpoint (SUR): Blood pressure
Study 20413122 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15745138 — Surrogate Endpoint (SUR): Blood pressure
Study 26745049 — Surrogate Endpoint (SUR): Blood pressure
Study 8503246 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12646336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12646336 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10357371 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15057739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28159782 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 17320021 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3314798 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22530354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18502991 — Surrogate Endpoint (SUR): Blood pressure
Study 30422390 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 30422390 — Surrogate Endpoint (SUR): Blood pressure
Study 23389750 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19091346 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 2332814 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16706961 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10977010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2285455 — Surrogate Endpoint (SUR): Blood pressure
Study 31154292 — Surrogate Endpoint (SUR): Blood pressure
Study 2894164 — Surrogate Endpoint (SUR): Blood pressure
Study 29883974 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29883974 — Surrogate Endpoint (SUR): Blood pressure
Study 24126611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24126611 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18306109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10977001 — Surrogate Endpoint (SUR): Bone mineral density
Study 10977001 — Surrogate Endpoint (SUR): Serum creatinine
Study 9358940 — Predictive Biomarker (PRD): MPZ mRNA
Genes: MPZ
Study 1490453 — Surrogate Endpoint (SUR): Blood pressure
Study 3885979 — Surrogate Endpoint (SUR): Serum potassium
Study 27691979 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 27691979 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 27691979 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 22357140 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 15848699 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 15848699 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 20363847 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 18699801 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10917990 — Surrogate Endpoint (SUR): Blood pressure
Study 8815753 — Surrogate Endpoint (SUR): Serum creatinine
Study 30590701 — Predictive Biomarker (PRD): AGO2 mRNA
Genes: AGO2; EIF2C2
Study 17707724 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 30171349 — Surrogate Endpoint (SUR): Blood pressure
Study 20033622 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 10442679 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30668228 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8847295 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 3880523 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3880523 — Surrogate Endpoint (SUR): Blood pressure
Study 24742508 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11245027 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11245027 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 3277481 — Surrogate Endpoint (SUR): Blood pressure
Study 15571424 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22850914 — Surrogate Endpoint (SUR): Blood pressure
Study 18408560 — Predictive Biomarker (PRD): CRHR2 mRNA
Genes: CRHR2; CRF2R; CRH2R
Study 15759530 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 1791612 — Surrogate Endpoint (SUR): Blood pressure
Study 12021221 — Surrogate Endpoint (SUR): Serum creatinine
Study 7762709 — Surrogate Endpoint (SUR): Blood pressure
Study 1972611 — Surrogate Endpoint (SUR): Blood pressure
Study 418585 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 22421927 — Surrogate Endpoint (SUR): Blood pressure
Study 6532586 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 12202470 — Surrogate Endpoint (SUR): Bone mineral density
Study 25805645 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 25805645 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 25805645 — Predictive Biomarker (PRD): MAOB mRNA
Genes: MAOB
Study 25805645 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 22458865 — Surrogate Endpoint (SUR): Bone mineral density
Study 14615876 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 14615876 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 14615876 — Surrogate Endpoint (SUR): Blood pressure
Study 14615876 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 30278428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30278428 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28136072 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 28136072 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17383282 — Surrogate Endpoint (SUR): Serum creatinine
Study 18066449 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2136939 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2136939 — Surrogate Endpoint (SUR): Blood pressure
Study 30217118 — Surrogate Endpoint (SUR): Bone mineral density
Study 28395131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24916837 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 19109408 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19109408 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 19109408 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 29490090 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 21891972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21891972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21891972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12624611 — Surrogate Endpoint (SUR): Blood pressure
Study 1859762 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1970466 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30194887 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22178539 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 18637638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18637638 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29131352 — Predictive Biomarker (PRD): GRIK1 mRNA
Genes: GRIK1; GLUR5
Study 29131352 — Predictive Biomarker (PRD): GABRA2 mRNA
Genes: GABRA2
Study 24831989 — Surrogate Endpoint (SUR): Blood pressure
Study 15364757 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31359357 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25919112 — Predictive Biomarker (PRD): TAAR6 mRNA
Genes: TAAR6; TA4; TAR4; TRAR4
Study 8250106 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25901097 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17827929 — Surrogate Endpoint (SUR): Bone mineral density
Study 2901818 — Surrogate Endpoint (SUR): Blood pressure
Study 26019023 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26019023 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22366739 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 21452357 — Surrogate Endpoint (SUR): Bone mineral density
Study 9256140 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29808033 — Surrogate Endpoint (SUR): Blood pressure
Study 26329473 — Surrogate Endpoint (SUR): Blood pressure
Study 26329473 — Surrogate Endpoint (SUR): Serum uric acid
Study 12741624 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8833207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8833207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8833207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22644009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15671101 — Predictive Biomarker (PRD): SCARB1 mRNA
Genes: SCARB1; CD36L1; CLA1
Study 10391396 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10391396 — Surrogate Endpoint (SUR): Blood pressure
Study 15759454 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 15759454 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 15759454 — Predictive Biomarker (PRD): IRS2 mRNA
Genes: IRS2
Study 7732693 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7732693 — Surrogate Endpoint (SUR): Blood pressure
Study 17577003 — Surrogate Endpoint (SUR): Bone mineral density
Study 23358123 — Surrogate Endpoint (SUR): Blood pressure
Study 23358123 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15200749 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15200749 — Surrogate Endpoint (SUR): Bone mineral density
Study 9728832 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21122699 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21122699 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18295172 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8748566 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31552981 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21323872 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 15895314 — Surrogate Endpoint (SUR): Bone mineral density
Study 9815298 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7851032 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7851032 — Surrogate Endpoint (SUR): Blood pressure
Study 18440821 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 18440821 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17137905 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 6270996 — Surrogate Endpoint (SUR): Blood pressure
Study 28296581 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 23826907 — Surrogate Endpoint (SUR): Serum creatinine
Study 11529246 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 11529246 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 9631952 — Safety Biomarker (SAF): DRD2
Study 7836186 — Surrogate Endpoint (SUR): Bone mineral density
Study 23314060 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 23314060 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21187295 — Surrogate Endpoint (SUR): Bone mineral density
Study 12708602 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 24831919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24831919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22277266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16008114 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16008114 — Surrogate Endpoint (SUR): Blood pressure
Study 1914031 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27781372 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 25263017 — Surrogate Endpoint (SUR): Serum creatinine
Study 22846608 — Predictive Biomarker (PRD): SRCIN1 mRNA
Genes: SRCIN1; KIAA1684; P140; SNIP
Study 22846608 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15247115 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 6367784 — Surrogate Endpoint (SUR): Blood pressure
Study 14594344 — Surrogate Endpoint (SUR): Serum testosterone
Study 27054908 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 23027801 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 18245148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18245148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18245148 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30198828 — Surrogate Endpoint (SUR): Blood pressure
Study 20679151 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20679151 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20679151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20679151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16109532 — Surrogate Endpoint (SUR): Blood pressure
Study 12441019 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12441019 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10419077 — Surrogate Endpoint (SUR): Blood pressure
Study 2185694 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 25046624 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 30282447 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 22348439 — Surrogate Endpoint (SUR): Blood pressure
Study 17494795 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 20587101 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12034949 — Surrogate Endpoint (SUR): Serum creatinine
Study 22474066 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 14737854 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31822498 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31822498 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 31822498 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 31822498 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 6849160 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 23786900 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23786900 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23786900 — Surrogate Endpoint (SUR): Serum uric acid
Study 15940624 — Monitoring Biomarker (MOI): HBV DNA