TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19166443 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 19166443 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19166443 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19166443 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23069315 — Monitoring Biomarker (MOI): HBV DNA
Study 17898183 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 31339232 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22187792 — Surrogate Endpoint (SUR): Blood pressure
Study 19001516 — Surrogate Endpoint (SUR): Blood pressure
Study 19001516 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19001516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22094092 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22094092 — Surrogate Endpoint (SUR): Blood pressure
Study 3546611 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 3546611 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12825092 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 15882879 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 19194341 — Surrogate Endpoint (SUR): Blood pressure
Study 16014067 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 6184567 — Surrogate Endpoint (SUR): Blood pressure
Study 20636634 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 9871427 — Surrogate Endpoint (SUR): Blood pressure
Study 8563674 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30937600 — Safety Biomarker (SAF): IL-6 and IL-10
Study 26299324 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 24060577 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24060577 — Surrogate Endpoint (SUR): Pathological complete response
Study 21119518 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18069178 — Surrogate Endpoint (SUR): Probing pocket depth
Study 27368430 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26556688 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study 26556688 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 20592389 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9893539 — Surrogate Endpoint (SUR): Blood pressure
Study 15164336 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 15164336 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 15164336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28687830 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21252053 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17000366 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29724499 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24088680 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12716076 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12716076 — Surrogate Endpoint (SUR): Blood pressure
Study 22830016 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 7768497 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24382970 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16673014 — Surrogate Endpoint (SUR): Blood pressure
Study 1679661 — Surrogate Endpoint (SUR): Blood pressure
Study 18635497 — Surrogate Endpoint (SUR): Serum creatinine
Study 10627728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10627728 — Surrogate Endpoint (SUR): Bone mineral density
Study 2537560 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2537560 — Surrogate Endpoint (SUR): Blood pressure
Study 20438562 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 15988144 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 15988144 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 2505642 — Surrogate Endpoint (SUR): Blood pressure
Study 28639445 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 28639445 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16378790 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31476826 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 1282602 — Surrogate Endpoint (SUR): Blood pressure
Study 1282602 — Surrogate Endpoint (SUR): Serum potassium
Study 22790403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22790403 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 22790403 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 22790403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22790403 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22790403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19932167 — Predictive Biomarker (PRD): MUTYH mRNA
Genes: MUTYH; MYH
Study 19932167 — Safety Biomarker (SAF): Interleukin 1
Study 17380213 — Surrogate Endpoint (SUR): Blood pressure
Study 17380213 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15674307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20632462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20632462 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20632462 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8227917 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8227917 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23443332 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 23147689 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23147689 — Surrogate Endpoint (SUR): Blood pressure
Study 20879881 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20879881 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23784346 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 25677679 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23305631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15961340 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31896134 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 28324167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18495735 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18495735 — Surrogate Endpoint (SUR): Bone mineral density
Study 18495735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18495735 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16343085 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 12475462 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 8944402 — Surrogate Endpoint (SUR): Blood pressure
Study 23648056 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 30720733 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19018087 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 29959802 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20947383 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18536386 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 15023658 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 26903143 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 21937520 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20040875 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12028174 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 7879787 — Surrogate Endpoint (SUR): Blood pressure
Study 7879787 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30635159 — Predictive Biomarker (PRD): NAGLU mRNA
Genes: NAGLU; UFHSD1
Study 19099160 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30120476 — Monitoring Biomarker (MOI): Cell-free DNA
Study 21211299 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10988281 — Surrogate Endpoint (SUR): Blood pressure
Study 30523133 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 15292314 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11133904 — Surrogate Endpoint (SUR): Serum testosterone
Study 29351791 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 14673725 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28921841 — Predictive Biomarker (PRD): L1CAM mRNA
Genes: L1CAM; CAML1; MIC5
Study 28921841 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 26499146 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21325456 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 21325456 — Surrogate Endpoint (SUR): Serum calcium
Study 21325456 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 21325456 — Surrogate Endpoint (SUR): Serum creatinine
Study 15040783 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15040783 — Surrogate Endpoint (SUR): Blood pressure
Study 11828273 — Surrogate Endpoint (SUR): Bone mineral density
Study 27814282 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27814282 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25948027 — Surrogate Endpoint (SUR): Blood pressure
Study 22954665 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29133605 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29133605 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28195970 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28195970 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23839771 — Predictive Biomarker (PRD): CSMD1 mRNA
Genes: CSMD1; KIAA1890; UNQ5952/PRO19863
Study 21447413 — Surrogate Endpoint (SUR): Bone mineral density
Study 22562554 — Surrogate Endpoint (SUR): Serum potassium
Study 16182674 — Surrogate Endpoint (SUR): Blood pressure
Study 8932548 — Predictive Biomarker (PRD): NAPA mRNA
Genes: NAPA; SNAPA
Study 6732679 — Surrogate Endpoint (SUR): Serum potassium
Study 6732679 — Surrogate Endpoint (SUR): Serum sodium
Study 31984508 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 31984508 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 31984508 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20398352 — Surrogate Endpoint (SUR): Bone mineral density
Study 20398352 — Predictive Biomarker (PRD): Hormone receptor
Study 17357850 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 8412202 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 23527715 — Safety Biomarker (SAF): Hyaluronic acid
Study 16947783 — Predictive Biomarker (PRD): AMPD1 mRNA
Genes: AMPD1
Study 16947783 — Predictive Biomarker (PRD): ATIC mRNA
Genes: ATIC; PURH; OK/SW-cl.86
Study 16947783 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 16947783 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 16947783 — Predictive Biomarker (PRD): MTRR mRNA
Genes: MTRR
Study 30194992 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 30194992 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 30194992 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 30194992 — Predictive Biomarker (PRD): CCL26 mRNA
Genes: CCL26; SCYA26; UNQ216/PRO242
Study 30194992 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 30194992 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 30194992 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 30194992 — Predictive Biomarker (PRD): LORICRIN mRNA
Genes: LORICRIN; LOR; LRN
Study 22356267 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 22356267 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22356267 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15895312 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22744627 — Surrogate Endpoint (SUR): Serum creatinine
Study 17461735 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2066757 — Predictive Biomarker (PRD): MIOS mRNA
Genes: MIOS
Study 31347669 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9315984 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 3533203 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 21458721 — Surrogate Endpoint (SUR): Serum testosterone
Study 14513073 — Surrogate Endpoint (SUR): Blood pressure
Study 14513073 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10904510 — Surrogate Endpoint (SUR): Blood pressure
Study 3712636 — Surrogate Endpoint (SUR): Blood pressure
Study 3712636 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3712636 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31596971 — Surrogate Endpoint (SUR): Blood pressure
Study 25583272 — Surrogate Endpoint (SUR): Blood pressure
Study 17205821 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25390761 — Surrogate Endpoint (SUR): Blood pressure
Study 25390761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6774674 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26317662 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 20725056 — Surrogate Endpoint (SUR): Blood pressure
Study 3621989 — Surrogate Endpoint (SUR): Blood pressure
Study 22079797 — Safety Biomarker (SAF): Interleukin 1
Study 22079797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22079797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20044087 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20044087 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 20044087 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 20044087 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10516451 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10150489 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 27400374 — Predictive Biomarker (PRD): Cadherin-13
Genes: CDH13; CDHH
Study 27400374 — Predictive Biomarker (PRD): TFPI2 mRNA
Genes: TFPI2
Study 27400374 — Predictive Biomarker (PRD): FSTL1 mRNA
Genes: FSTL1; FRP
Study 24766239 — Surrogate Endpoint (SUR): Blood pressure
Study 17233861 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 15782501 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 12149108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12149108 — Safety Biomarker (SAF): Reactive oxygen species
Study 27061732 — Surrogate Endpoint (SUR): Blood pressure
Study 25792627 — Surrogate Endpoint (SUR): Bone mineral density
Study 27515331 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 22543981 — Predictive Biomarker (PRD): ADRA2C mRNA
Genes: ADRA2C; ADRA2L2; ADRA2RL2
Study 22543981 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 22543981 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 22543981 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19556358 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 17402274 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17402274 — Surrogate Endpoint (SUR): Blood pressure
Study 15613923 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 21989146 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 23176073 — Predictive Biomarker (PRD): MAOB mRNA
Genes: MAOB
Study 20885016 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20885016 — Surrogate Endpoint (SUR): Blood pressure
Study 24412053 — Safety Biomarker (SAF): miR-9
Study 24412053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 24412053 — Predictive Biomarker (PRD): miR-31
Genes: MIR31
Study 24412053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-34a
Genes: MIR34A
Study 24412053 — Safety Biomarker (SAF): miR-137
Genes: MIR137
Study 21895939 — Safety Biomarker (SAF): Hyaluronic acid
Study 3469982 — Surrogate Endpoint (SUR): Blood pressure
Study 3469982 — Surrogate Endpoint (SUR): Serum calcium
Study 3469982 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31629353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16619217 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10966839 — Predictive Biomarker (PRD): GYPC mRNA
Genes: GYPC; GLPC; GPC
Study 22051419 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8683251 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30383670 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30383670 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30383670 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9199818 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 9199818 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9199818 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31131629 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 31131629 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28842727 — Surrogate Endpoint (SUR): Bone mineral density
Study 23897585 — Predictive Biomarker (PRD): SFTPB mRNA
Genes: SFTPB; SFTP3
Study 15315111 — Surrogate Endpoint (SUR): Blood pressure
Study 11692092 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28482877 — Safety Biomarker (SAF): Epiregulin
Genes: EREG
Study 17907228 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 17907228 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17907228 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 17907228 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6995513 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25833066 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10469856 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 6577782 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30520691 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16488299 — Surrogate Endpoint (SUR): Serum creatinine
Study 8409070 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21903895 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21903895 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 16324850 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 1827086 — Surrogate Endpoint (SUR): Blood pressure
Study 28242040 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28242040 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 28242040 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 25762461 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 23650397 — Predictive Biomarker (PRD): SGK1 mRNA
Genes: SGK1; SGK
Study 9028540 — Surrogate Endpoint (SUR): Bone mineral density
Study 29920123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21310284 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 28400200 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 14987306 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8697308 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6141724 — Surrogate Endpoint (SUR): Blood pressure
Study 26530743 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24084072 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24084072 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21961181 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 21961181 — Predictive Biomarker (PRD): SAT2 mRNA
Genes: SAT2; SSAT2
Study 10895372 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25262434 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25262434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15908647 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 12935395 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 11214769 — Surrogate Endpoint (SUR): Blood pressure
Study 6343656 — Surrogate Endpoint (SUR): Blood pressure
Study 31322833 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 20823391 — Surrogate Endpoint (SUR): Blood pressure
Study 15805799 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 22231536 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 15110130 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15110130 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11260540 — Surrogate Endpoint (SUR): Blood pressure
Study 11260540 — Surrogate Endpoint (SUR): Serum creatinine
Study 19013293 — Safety Biomarker (SAF): Thyroid stimulating hormone