TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9102590 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25720808 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 15304576 — Surrogate Endpoint (SUR): Blood pressure
Study 9762782 — Surrogate Endpoint (SUR): Blood pressure
Study 9762782 — Surrogate Endpoint (SUR): Serum potassium
Study 17917501 — Surrogate Endpoint (SUR): Blood pressure
Study 5763957 — Surrogate Endpoint (SUR): Blood pressure
Study 26867199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25711318 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7850232 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28711577 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 19468216 — Surrogate Endpoint (SUR): Blood pressure
Study 2942062 — Surrogate Endpoint (SUR): Blood pressure
Study 28351962 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 15097300 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15097300 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11594571 — Safety Biomarker (SAF): Interleukin 12
Study 7989456 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 2919093 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 30700344 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27776372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27776372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10509160 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10509160 — Predictive Biomarker (PRD): VEGFC mRNA
Genes: VEGFC
Study 10509160 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 10509160 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24767614 — Surrogate Endpoint (SUR): Blood pressure
Study 22679718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22679718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22679718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10352334 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 11296164 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9311490 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2878745 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 28111428 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23967632 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 8884896 — Safety Biomarker (SAF): Reactive oxygen species
Study 1414398 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30045749 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 26295868 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27372560 — Surrogate Endpoint (SUR): Blood pressure
Study 24404797 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16462818 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12478093 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12478093 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12478093 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10735889 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10735889 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10735889 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8774551 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 30094725 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30094725 — Surrogate Endpoint (SUR): Blood pressure
Study 26228276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25012934 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22528165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18482525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25108482 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 21960369 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 19838130 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 19838130 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16284465 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 25355722 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8643884 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 27177587 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 7774741 — Surrogate Endpoint (SUR): Blood pressure
Study 2191071 — Surrogate Endpoint (SUR): Blood pressure
Study 2191071 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26285020 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24343092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24343092 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 24343092 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24343092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19615730 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9402612 — Surrogate Endpoint (SUR): Blood pressure
Study 17573492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17573492 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17573492 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16213352 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30476217 — Surrogate Endpoint (SUR): Bone mineral density
Study 23437909 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 23437909 — Surrogate Endpoint (SUR): Blood pressure
Study 21300674 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11199186 — Surrogate Endpoint (SUR): Bone mineral density
Study 18953082 — Surrogate Endpoint (SUR): Blood pressure
Study 6111438 — Surrogate Endpoint (SUR): Serum potassium
Study 9579771 — Surrogate Endpoint (SUR): Blood pressure
Study 20507969 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 27835613 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19106767 — Surrogate Endpoint (SUR): Blood pressure
Study 17049767 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15147428 — Surrogate Endpoint (SUR): Serum creatinine
Study 15147428 — Surrogate Endpoint (SUR): Blood pressure
Study 7759715 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30708350 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29098244 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 25935771 — Surrogate Endpoint (SUR): Serum uric acid
Study 25935771 — Surrogate Endpoint (SUR): Blood pressure
Study 2199148 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21997315 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 21997315 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 11693335 — Monitoring Biomarker (MOI): HBV DNA
Study 9469525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2907519 — Surrogate Endpoint (SUR): Blood pressure
Study 28994705 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21692281 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22922507 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22922507 — Surrogate Endpoint (SUR): Blood pressure
Study 18678836 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1846940 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22128083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15805203 — Surrogate Endpoint (SUR): Bone mineral density
Study 12578811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 1748137 — Surrogate Endpoint (SUR): Blood pressure
Study 23321257 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 23321257 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 20872043 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 20872043 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 10945486 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 10945486 — Surrogate Endpoint (SUR): Serum creatinine
Study 24275841 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 14708413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14708413 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 14708413 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 11236258 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11236258 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11236258 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8640161 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8640161 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20473991 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1817898 — Surrogate Endpoint (SUR): Blood pressure
Study 28274246 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28274246 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23032742 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 12226037 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9381718 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 3768492 — Surrogate Endpoint (SUR): Blood pressure
Study 28988765 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30355323 — Safety Biomarker (SAF): Hyaluronic acid
Study 12791430 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 7503006 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1820293 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31755915 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 31755915 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 25788320 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23600363 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19404617 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16940077 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8379674 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31356703 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 21875880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21875880 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26522083 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 16186270 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23299714 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23299714 — Surrogate Endpoint (SUR): Serum potassium
Study 23299714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23299714 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20606776 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11134441 — Predictive Biomarker (PRD): HRC mRNA
Genes: HRC; HCP
Study 11134441 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11134441 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 31500854 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 28476766 — Predictive Biomarker (PRD): SLC25A20 mRNA
Genes: SLC25A20; CAC; CACT
Study 21270370 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19697824 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8526836 — Surrogate Endpoint (SUR): Blood pressure
Study 2487539 — Surrogate Endpoint (SUR): Blood pressure
Study 31404668 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 21995887 — Predictive Biomarker (PRD): RHCE mRNA
Genes: RHCE; RHC; RHE
Study 11729513 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 31079530 — Surrogate Endpoint (SUR): Blood pressure
Study 26387142 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26387142 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26387142 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26387142 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 26387142 — Predictive Biomarker (PRD): PDCD1LG2 mRNA
Genes: PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2
Study 26387142 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 26387142 — Predictive Biomarker (PRD): CD8A mRNA
Genes: CD8A; MAL
Study 23942540 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 21673612 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 31077873 — Predictive Biomarker (PRD): CHRM3 mRNA
Genes: CHRM3
Study 31077873 — Predictive Biomarker (PRD): IL2RB mRNA
Genes: IL2RB; IL15RB
Study 31077873 — Predictive Biomarker (PRD): KCNB2 mRNA
Genes: KCNB2
Study 31077873 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 31077873 — Predictive Biomarker (PRD): HTR3A mRNA
Genes: HTR3A; 5HT3R; HTR3
Study 31647774 — Surrogate Endpoint (SUR): Blood pressure
Study 23301548 — Monitoring Biomarker (MOI): HBV DNA
Study 15349912 — Monitoring Biomarker (MOI): HBV DNA
Study 10759446 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10759446 — Surrogate Endpoint (SUR): Blood pressure
Study 20197607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20197607 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16145640 — Surrogate Endpoint (SUR): Blood pressure
Study 8194628 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31626156 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 23709583 — Surrogate Endpoint (SUR): Blood pressure
Study 19704066 — Predictive Biomarker (PRD): Hormone receptor
Study 22029963 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22029963 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 30422319 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22791766 — Surrogate Endpoint (SUR): Bone mineral density
Study 17586184 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 15642679 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study 15642679 — Surrogate Endpoint (SUR): Hematologic response
Study 15463835 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 15463835 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8950783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8950783 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30646822 — Surrogate Endpoint (SUR): Blood pressure
Study 21175274 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15108766 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 15108766 — Surrogate Endpoint (SUR): Serum creatinine
Study 11411908 — Surrogate Endpoint (SUR): Serum creatinine
Study 31448116 — Predictive Biomarker (PRD): MSR1 mRNA
Genes: MSR1; SCARA1
Study 31448116 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 31448116 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 31448116 — Predictive Biomarker (PRD): INSIG1 mRNA
Genes: INSIG1
Study 31448116 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 31448116 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 31448116 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study 24266299 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21410733 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 14633563 — Surrogate Endpoint (SUR): Blood pressure
Study 30261738 — Predictive Biomarker (PRD): PTBP2 mRNA
Genes: PTBP2; NPTB; PTB; PTBLP
Study 19124398 — Surrogate Endpoint (SUR): Blood pressure
Study 9451066 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 9451066 — Surrogate Endpoint (SUR): Serum creatinine
Study 2527473 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2527473 — Surrogate Endpoint (SUR): Blood pressure
Study 31943297 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 31943297 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study 10676687 — Surrogate Endpoint (SUR): Blood pressure
Study 29108664 — Surrogate Endpoint (SUR): Blood pressure
Study 26545726 — Safety Biomarker (SAF): Interleukin 1
Study 26545726 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20513863 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 8227449 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 3762014 — Surrogate Endpoint (SUR): Blood pressure
Study 25657183 — Surrogate Endpoint (SUR): Blood pressure
Study 21508090 — Safety Biomarker (SAF): MTHFR
Study 19540137 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 16282699 — Surrogate Endpoint (SUR): Bone mineral density
Study 16282699 — Surrogate Endpoint (SUR): Serum calcium
Study 11287080 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 11287080 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11287080 — Surrogate Endpoint (SUR): Blood pressure
Study 27665225 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27665225 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 24643340 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 24643340 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 24643340 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 24643340 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 16020407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16020407 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16020407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12501950 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 12501950 — Surrogate Endpoint (SUR): Blood pressure
Study 15951873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10068580 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10068580 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28030716 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26340807 — Safety Biomarker (SAF): Hyaluronic acid
Study 23582742 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 1764497 — Surrogate Endpoint (SUR): Blood pressure
Study 7123111 — Surrogate Endpoint (SUR): Blood pressure
Study 31638491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 31638491 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25541333 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24285582 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19532100 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19532100 — Surrogate Endpoint (SUR): Blood pressure
Study 17431603 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 11354304 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 26514192 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26514192 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18082233 — Predictive Biomarker (PRD): DHFR mRNA
Genes: DHFR
Study 18082233 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 3739582 — Surrogate Endpoint (SUR): Blood pressure
Study 27126957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27126957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27126957 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22520791 — Surrogate Endpoint (SUR): Blood pressure
Study 19643310 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19643310 — Surrogate Endpoint (SUR): Blood pressure
Study 7753739 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29615077 — Predictive Biomarker (PRD): UBC mRNA
Genes: UBC
Study 29615077 — Surrogate Endpoint (SUR): Pathological complete response
Study 18793361 — Surrogate Endpoint (SUR): Bacterial count
Study 1732896 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16326671 — Surrogate Endpoint (SUR): Blood pressure
Study 22367128 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP