TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00402090 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study NCT02793739 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03868085 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01860599 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01201720 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02108561 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01559025 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02384746 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04577378 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04577378 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT04577378 — Predictive Biomarker (PRD): IFNAR1 mRNA
Genes: IFNAR1; IFNAR
Study NCT04577378 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study NCT04577378 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01698502 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00430768 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT03617276 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT01205022 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01292187 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03466047 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT01669486 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02691559 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study NCT02133898 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study NCT02133898 — Predictive Biomarker (PRD): MTRR mRNA
Genes: MTRR
Study NCT02133898 — Safety Biomarker (SAF): MTHFR
Study NCT02693028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00230750 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02339532 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study NCT02339532 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00631904 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT00631904 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT01863147 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01448577 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT01448577 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01371695 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT04126200 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT02483039 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02318082 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00463190 — Surrogate Endpoint (SUR): Bacterial count
Study NCT02921243 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT03312556 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05523648 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03622736 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03616548 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study NCT00723619 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study NCT03701568 — Predictive Biomarker (PRD): TK2 mRNA
Genes: TK2
Study NCT02729766 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02729766 — Surrogate Endpoint (SUR): Serum sodium
Study NCT02078440 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01187628 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03738475 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT00004863 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT02552030 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01384162 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00927134 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04367064 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01022320 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00350038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00350038 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00003877 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02332460 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03486067 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT01298011 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study NCT04372199 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study NCT04372199 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT02718131 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00667823 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01492374 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04385186 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01354158 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02725632 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study NCT02725632 — Predictive Biomarker (PRD): RBM25 mRNA
Genes: RBM25; RNPC7
Study NCT02725632 — Predictive Biomarker (PRD): LUC7L3 mRNA
Genes: LUC7L3; CREAP1; CROP; O48
Study NCT02725632 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT03857659 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study NCT02952521 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT00441259 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01613209 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04277884 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01682265 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study NCT01298661 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02944279 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study NCT01139632 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT00310089 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03427151 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study NCT01042561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00252525 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03698253 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03698253 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00536653 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00536653 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01280487 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01408953 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01408953 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01848873 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01364337 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00154531 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT03804177 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03769142 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02102438 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03805789 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT04297839 — Surrogate Endpoint (SUR): Serum calcium
Study NCT04297839 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00013689 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03411759 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT04215445 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02418000 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02418000 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT02418000 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study NCT03557671 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT01114880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04033302 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT02408991 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT06725342 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03780738 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study NCT01074086 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study NCT02935335 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04522986 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02576067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04602325 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT04602325 — Predictive Biomarker (PRD): UCHL1 mRNA
Genes: UCHL1
Study NCT00868439 — Surrogate Endpoint (SUR): Serum potassium
Study NCT01521221 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04047472 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03020030 — Surrogate Endpoint (SUR): Serum asparaginase
Study NCT01985191 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02500849 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02500849 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02626455 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00325468 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04478968 — Predictive Biomarker (PRD): MMP7 mRNA
Genes: MMP7; MPSL1; PUMP1
Study NCT04478968 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT03732209 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02660034 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00422942 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01622062 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT05025306 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT00673335 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00673335 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02257489 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00657982 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT00657982 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00657982 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT00071461 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT03090529 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02508012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03765554 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study NCT03765554 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT03765554 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study NCT03884751 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT01049425 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01049425 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02987465 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02729441 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03192202 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT01038830 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03529604 — Predictive Biomarker (PRD): SERPINB3 mRNA
Genes: SERPINB3; SCCA; SCCA1
Study NCT03529604 — Predictive Biomarker (PRD): TACSTD2 mRNA
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT02959437 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT02959437 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT00068757 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01388816 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT01388816 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01388816 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06748040 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study NCT00576069 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02999906 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02363946 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00825188 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01937676 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT00020917 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00020917 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01161316 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02346461 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study NCT02346461 — Safety Biomarker (SAF): N-acetylneuraminic acid
Study NCT01243138 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02120274 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02688686 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT04278144 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03245125 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01262859 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01262859 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03674112 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03674112 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04219111 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04219111 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00732875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04109391 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03666871 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT03666871 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04266587 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01249066 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT03772067 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT03772067 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT03772067 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02620592 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02549261 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02549261 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03013114 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT03754348 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT03911557 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT00952016 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study NCT02569268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02569268 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03899792 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01909999 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT01909999 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT00433979 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01247727 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01892072 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02275663 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00530127 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT03480334 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03545438 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04647747 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03192462 — Predictive Biomarker (PRD): MAGEA4 mRNA
Genes: MAGEA4; MAGE4
Study NCT03192462 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study NCT02859077 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04358432 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04358432 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04158947 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04356053 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study NCT02666664 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04805723 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04491877 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01622894 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study NCT01622894 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study NCT03749746 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02223234 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02223234 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02223234 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02355964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04806971 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT04806971 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study NCT04806971 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study NCT03626792 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02208713 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01574235 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02657226 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02847429 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT04747600 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03460223 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01664182 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01664182 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03836768 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04293185 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02677870 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01886651 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study NCT01290614 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04747847 — Safety Biomarker (SAF): Interleukin 1
Study NCT05214872 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT05214872 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT05214872 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05214872 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT05214872 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT05214872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05214872 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT05214872 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02906150 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00509470 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01883362 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT03104179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03104179 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT00529880 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04676295 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01951560 — Pharmacodynamic Biomarker (PDY): Valproic acid