TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29969473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29969473 — Safety Biomarker (SAF): IL-6 and IL-10
Study 26407603 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26407603 — Surrogate Endpoint (SUR): Blood pressure
Study 22683955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22683955 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11177189 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 26477027 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29264937 — Monitoring Biomarker (MOI): Procalcitonin
Study 11247403 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 9262430 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9262430 — Surrogate Endpoint (SUR): Blood pressure
Study 9262430 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30144513 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 30144513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12929292 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 8843769 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 21057977 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 282700 — Surrogate Endpoint (SUR): Blood pressure
Study 16480566 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 12871871 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30849931 — Surrogate Endpoint (SUR): Blood pressure
Study 27697868 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20501479 — Surrogate Endpoint (SUR): Blood pressure
Study 8522408 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2678209 — Surrogate Endpoint (SUR): Blood pressure
Study 7837863 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 11230838 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3055923 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31811995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31811995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23277482 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 8670317 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 30426791 — Surrogate Endpoint (SUR): Bone mineral density
Study 27347650 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 31855906 — Safety Biomarker (SAF): Hyaluronic acid
Study 28886992 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 28886992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28886992 — Surrogate Endpoint (SUR): Blood pressure
Study 26123410 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 28598231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28598231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17853751 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 30458778 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24239324 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 28343659 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 12603860 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10934653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10934653 — Safety Biomarker (SAF): Interleukin 1
Study 10934653 — Surrogate Endpoint (SUR): Bone mineral density
Study 8165610 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8165610 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8165610 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 19255393 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17061441 — Surrogate Endpoint (SUR): Blood pressure
Study 11697840 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10970684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10970684 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8792771 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 1467127 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 6419809 — Surrogate Endpoint (SUR): Blood pressure
Study 16000966 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 29209783 — Surrogate Endpoint (SUR): Blood pressure
Study 8554929 — Surrogate Endpoint (SUR): Blood pressure
Study 2316590 — Surrogate Endpoint (SUR): Blood pressure
Study 6299842 — Predictive Biomarker (PRD): NFU1 mRNA
Genes: NFU1; HIRIP5; CGI-33
Study 19327620 — Surrogate Endpoint (SUR): Blood pressure
Study 16447051 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17805229 — Surrogate Endpoint (SUR): Blood pressure
Study 16148211 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 12790209 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9023716 — Surrogate Endpoint (SUR): Blood pressure
Study 9023716 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7505008 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2881786 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27504914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19404392 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11149996 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7584951 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 7584951 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 31027477 — Surrogate Endpoint (SUR): Blood pressure
Study 25791173 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 3743860 — Surrogate Endpoint (SUR): Blood pressure
Study 27955663 — Surrogate Endpoint (SUR): Blood pressure
Study 21132128 — Surrogate Endpoint (SUR): Blood pressure
Study 1730841 — Safety Biomarker (SAF): Reactive oxygen species
Study 6486559 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30270639 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 30270639 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21095280 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10781471 — Surrogate Endpoint (SUR): Blood pressure
Study 3883734 — Surrogate Endpoint (SUR): Blood pressure
Study 20087785 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 12479668 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 31149842 — Surrogate Endpoint (SUR): Blood pressure
Study 14640255 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14640255 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26066335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26066335 — Safety Biomarker (SAF): BDNF
Study 24476477 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24476477 — Safety Biomarker (SAF): BDNF
Study 19364302 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9364979 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29567321 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24475777 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study 22268125 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18180567 — Safety Biomarker (SAF): Hyaluronic acid
Study 12512229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12512229 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7695972 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24045793 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 19549707 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 7870637 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7870637 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20643762 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 15937580 — Surrogate Endpoint (SUR): Serum testosterone
Study 8899091 — Monitoring Biomarker (MOI): HBV DNA
Study 30431588 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 30431588 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 21913966 — Surrogate Endpoint (SUR): Blood pressure
Study 20225658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7598919 — Surrogate Endpoint (SUR): Blood pressure
Study 31888605 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9281254 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9281254 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8193733 — Surrogate Endpoint (SUR): Blood pressure
Study 29508153 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29508153 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 7898088 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7898088 — Surrogate Endpoint (SUR): Blood pressure
Study 11049919 — Surrogate Endpoint (SUR): Serum creatinine
Study 11049919 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30201310 — Predictive Biomarker (PRD): TCP1 mRNA
Genes: TCP1; CCT1; CCTA
Study 23257008 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23257008 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2045865 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31261967 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17520105 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17520105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11336714 — Surrogate Endpoint (SUR): Blood pressure
Study 31406997 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31406997 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 31406997 — Predictive Biomarker (PRD): TLR5 mRNA
Genes: TLR5; TIL3
Study 31406997 — Predictive Biomarker (PRD): MAP3K7 mRNA
Genes: MAP3K7; TAK1
Study 31406997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31406997 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 24625704 — Safety Biomarker (SAF): BDNF
Study 7752862 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31525164 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25986458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12820919 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1794742 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 1794742 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1794742 — Surrogate Endpoint (SUR): Blood pressure
Study 30947751 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23184120 — Surrogate Endpoint (SUR): Blood pressure
Study 29445029 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 29445029 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 14498766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10875526 — Surrogate Endpoint (SUR): Bone mineral density
Study 29330008 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 15139775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11773939 — Surrogate Endpoint (SUR): Blood pressure
Study 2674713 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2674713 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31177183 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25637266 — Predictive Biomarker (PRD): NE
Study 2285608 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 28166816 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 26063161 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18758699 — Surrogate Endpoint (SUR): Blood pressure
Study 16644608 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8651712 — Surrogate Endpoint (SUR): Serum creatinine
Study 22891946 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 22891946 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22891946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20164553 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 7461012 — Surrogate Endpoint (SUR): Blood pressure
Study 31744796 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 31744796 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26001320 — Surrogate Endpoint (SUR): Blood pressure
Study 26866954 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 26866954 — Surrogate Endpoint (SUR): Bone mineral density
Study 1577054 — Surrogate Endpoint (SUR): Serum uric acid
Study 21944176 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21944176 — Surrogate Endpoint (SUR): Blood pressure
Study 16846541 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7840053 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7840053 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2369312 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18524974 — Surrogate Endpoint (SUR): Serum creatinine
Study 14653835 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23925644 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15958628 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10501821 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 30499486 — Surrogate Endpoint (SUR): Blood pressure
Study 17628912 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17882685 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15083368 — Surrogate Endpoint (SUR): Bone mineral density
Study 15083368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27771172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27771172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24467669 — Surrogate Endpoint (SUR): Bone mineral density
Study 24467669 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24297381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24297381 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30120894 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 23140661 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23709432 — Surrogate Endpoint (SUR): Serum creatinine
Study 21849080 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21849080 — Surrogate Endpoint (SUR): Serum creatinine
Study 21849080 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24374004 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 24374004 — Surrogate Endpoint (SUR): Blood pressure
Study 11691515 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9176870 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 9176870 — Safety Biomarker (SAF): Cytochrome c
Study 27276373 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 20958228 — Surrogate Endpoint (SUR): Blood pressure
Study 17191025 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2860992 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22818869 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28633996 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 28633996 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 20819537 — Surrogate Endpoint (SUR): Serum potassium
Study 8698278 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8698278 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31747864 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23698545 — Surrogate Endpoint (SUR): Blood pressure
Study 17381974 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 17381974 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17381974 — Surrogate Endpoint (SUR): Blood pressure
Study 17381974 — Surrogate Endpoint (SUR): Serum uric acid
Study 9481529 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 2096212 — Surrogate Endpoint (SUR): Blood pressure
Study 31940039 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28434547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30242335 — Surrogate Endpoint (SUR): Serum uric acid
Study 30242335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15964290 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 15964290 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 15964290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 2258142 — Monitoring Biomarker (MOI): HBV DNA
Study 20975267 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15786427 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 31038621 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 19225065 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17535997 — Surrogate Endpoint (SUR): Bone mineral density
Study 11040240 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 9083899 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8409183 — Surrogate Endpoint (SUR): Blood pressure
Study 31097858 — Surrogate Endpoint (SUR): Bone mineral density
Study 22933433 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7864916 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16556138 — Surrogate Endpoint (SUR): Bone mineral density
Study 8207316 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 3430969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26025383 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 23925377 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 23925377 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16608033 — Monitoring Biomarker (MOI): HBV DNA
Study 1921738 — Surrogate Endpoint (SUR): Bone mineral density
Study 20722752 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20722752 — Surrogate Endpoint (SUR): Bone mineral density
Study 12569218 — Surrogate Endpoint (SUR): Blood pressure
Study 31238312 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29880427 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9110111 — Surrogate Endpoint (SUR): Blood pressure
Study 3906163 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31230119 — Safety Biomarker (SAF): Hyaluronic acid
Study 10753249 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10753249 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21846985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17926624 — Surrogate Endpoint (SUR): Blood pressure
Study 26351332 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24905061 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23479456 — Surrogate Endpoint (SUR): Blood pressure
Study 29546309 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 29546309 — Predictive Biomarker (PRD): NFKB1 mRNA
Genes: NFKB1
Study 29546309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29546309 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26979085 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 25548744 — Surrogate Endpoint (SUR): Blood pressure
Study 15093982 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26962828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25315207 — Surrogate Endpoint (SUR): Blood pressure
Study 17628197 — Surrogate Endpoint (SUR): Blood pressure
Study 9534100 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9534100 — Surrogate Endpoint (SUR): Blood pressure
Study 31017657 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1