TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18552684 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12499279 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12499279 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7723402 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24165269 — Surrogate Endpoint (SUR): Blood pressure
Study 24165269 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21897113 — Surrogate Endpoint (SUR): Blood pressure
Study 21897113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20713790 — Surrogate Endpoint (SUR): Serum creatinine
Study 16001108 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 10614677 — Surrogate Endpoint (SUR): Bone mineral density
Study 19906103 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17293063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17293063 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 17293063 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17293063 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 17293063 — Predictive Biomarker (PRD): CXCL2 mRNA
Genes: CXCL2; GRO2; GROB; MIP2A; SCYB2
Study 10023308 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 12719279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8994512 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8994512 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8994512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8994512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8994512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17408407 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 16061711 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12429323 — Safety Biomarker (SAF): Hyaluronic acid
Study 22610590 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 9250102 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 9250102 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8282290 — Surrogate Endpoint (SUR): Blood pressure
Study 29982690 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11414776 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 29805306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29805306 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29805306 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27619215 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20484472 — Surrogate Endpoint (SUR): Serum testosterone
Study 16648513 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 16648513 — Predictive Biomarker (PRD): Hormone receptor
Study 12970132 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11191541 — Surrogate Endpoint (SUR): Serum creatinine
Study 9170041 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 1331788 — Surrogate Endpoint (SUR): Bone mineral density
Study 31582283 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 31582283 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26908041 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26908041 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17644545 — Surrogate Endpoint (SUR): Bone mineral density
Study 17644545 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1628722 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14705236 — Surrogate Endpoint (SUR): Bone mineral density
Study 7665805 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 25740537 — Safety Biomarker (SAF): DRD2
Study 8273616 — Surrogate Endpoint (SUR): Blood pressure
Study 28090203 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 18086800 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29793857 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 29793857 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9695717 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 9695717 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 29721714 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18697911 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 18697911 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 9931535 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26290749 — Surrogate Endpoint (SUR): Blood pressure
Study 15225192 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15225192 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15225192 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7838444 — Safety Biomarker (SAF): DRD2
Study 31974825 — Surrogate Endpoint (SUR): Blood pressure
Study 26205910 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 23527521 — Surrogate Endpoint (SUR): Blood pressure
Study 1947729 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 20050759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20050759 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 9849446 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 365391 — Surrogate Endpoint (SUR): Blood pressure
Study 15347709 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15347709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9504354 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9504354 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9504354 — Surrogate Endpoint (SUR): Blood pressure
Study 27488859 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8977510 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8977510 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 3912182 — Surrogate Endpoint (SUR): Blood pressure
Study 25115616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25825336 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19574322 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 17726081 — Surrogate Endpoint (SUR): Bone mineral density
Study 17726081 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21514398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21514398 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 12835516 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 30669280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19175929 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19175929 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17984247 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 19302559 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 29710111 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 27151508 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 20805273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18579510 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18579510 — Surrogate Endpoint (SUR): Serum testosterone
Study 11833023 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 1703909 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1703909 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 1703909 — Surrogate Endpoint (SUR): Blood pressure
Study 28724962 — Predictive Biomarker (PRD): NOD2 mRNA
Genes: NOD2; CARD15; IBD1
Study 28724962 — Predictive Biomarker (PRD): GBP5 mRNA
Genes: GBP5; UNQ2427/PRO4987
Study 28724962 — Predictive Biomarker (PRD): IFITM1 mRNA
Genes: IFITM1; CD225; IFI17
Study 28724962 — Predictive Biomarker (PRD): TNIP1 mRNA
Genes: TNIP1; KIAA0113; NAF1
Study 25755034 — Surrogate Endpoint (SUR): Blood pressure
Study 25755034 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3929308 — Surrogate Endpoint (SUR): Blood pressure
Study 29521661 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8441895 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 25148049 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20101593 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 20101593 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 20101593 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 3768929 — Surrogate Endpoint (SUR): Blood pressure
Study 3768929 — Surrogate Endpoint (SUR): Serum potassium
Study 18565100 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 18565100 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 28683994 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 25712416 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25767372 — Surrogate Endpoint (SUR): Blood pressure
Study 11431228 — Surrogate Endpoint (SUR): Blood pressure
Study 9731682 — Surrogate Endpoint (SUR): Blood pressure
Study 21085983 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9644320 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 22430270 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 20332125 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 8933850 — Surrogate Endpoint (SUR): Blood pressure
Study 6992822 — Surrogate Endpoint (SUR): Blood pressure
Study 6992822 — Surrogate Endpoint (SUR): Serum creatinine
Study 6992822 — Surrogate Endpoint (SUR): Serum potassium
Study 11056094 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22458601 — Surrogate Endpoint (SUR): Blood pressure
Study 28987237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25552526 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17612946 — Surrogate Endpoint (SUR): Blood pressure
Study 19538486 — Monitoring Biomarker (MOI): HBV DNA
Study 21438413 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 10426383 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10426383 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 10426383 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23381694 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17522388 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11350844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3582478 — Surrogate Endpoint (SUR): Plasma ammonia
Study 31188232 — Safety Biomarker (SAF): DRD2
Study 19201696 — Surrogate Endpoint (SUR): Sperm parameters
Study 10895373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8777471 — Surrogate Endpoint (SUR): Blood pressure
Study 30845829 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 19368581 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 15044507 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15044507 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 6778754 — Surrogate Endpoint (SUR): Blood pressure
Study 29803838 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study 15707560 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15707560 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1662376 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 30724002 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 30724002 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 29871676 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 27100457 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 2468913 — Surrogate Endpoint (SUR): Blood pressure
Study 25853591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25853591 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 25853591 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25853591 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22621750 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 12575377 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12575377 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28408655 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 28408655 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24278992 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 24278992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24278992 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17015551 — Surrogate Endpoint (SUR): Blood pressure
Study 25604900 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16518347 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16518347 — Surrogate Endpoint (SUR): Blood pressure
Study 1333962 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23246445 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10697395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10697395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21918905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18156033 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 7867676 — Surrogate Endpoint (SUR): Blood pressure
Study 21625085 — Surrogate Endpoint (SUR): Blood pressure
Study 23698160 — Safety Biomarker (SAF): MTHFR
Study 15998758 — Surrogate Endpoint (SUR): Blood pressure
Study 10574652 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10574652 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1715450 — Surrogate Endpoint (SUR): Blood pressure
Study 30527555 — Safety Biomarker (SAF): Hyaluronic acid
Study 19462490 — Surrogate Endpoint (SUR): Blood pressure
Study 22781864 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 15206496 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15206496 — Surrogate Endpoint (SUR): Blood pressure
Study 8207039 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 21296261 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16579706 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16579706 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 16579706 — Predictive Biomarker (PRD): NANOS1 mRNA
Genes: NANOS1; NOS1
Study 16579706 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 16579706 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16579706 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12928471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24324045 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19417110 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19417110 — Surrogate Endpoint (SUR): Blood pressure
Study 19417110 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 12599230 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12599230 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10674229 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 8456474 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 3531033 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3531033 — Surrogate Endpoint (SUR): Blood pressure
Study 28035345 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28035345 — Safety Biomarker (SAF): BDNF
Study 22892813 — Surrogate Endpoint (SUR): Blood pressure
Study 27630318 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25158772 — Surrogate Endpoint (SUR): Blood pressure
Study 12796154 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10860897 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3006981 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20143382 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 3545579 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3545579 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3545579 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29664001 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30807853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 29902295 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29902295 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24840756 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 18931201 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20974558 — Safety Biomarker (SAF): Hyaluronic acid
Study 9428493 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 788722 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24710470 — Surrogate Endpoint (SUR): Serum creatinine
Study 16103383 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11839141 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7821198 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 7821198 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26749533 — Surrogate Endpoint (SUR): Blood pressure
Study 20518225 — Surrogate Endpoint (SUR): Blood pressure
Study 17505694 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17505694 — Surrogate Endpoint (SUR): Blood pressure
Study 27998241 — Surrogate Endpoint (SUR): Bone mineral density
Study 17974502 — Surrogate Endpoint (SUR): Blood pressure
Study 10995520 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6437575 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27653164 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27653164 — Surrogate Endpoint (SUR): Blood pressure
Study 25483553 — Surrogate Endpoint (SUR): Blood pressure
Study 23242248 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9817475 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9817475 — Surrogate Endpoint (SUR): Blood pressure
Study 25792492 — Predictive Biomarker (PRD): Hormone receptor
Study 25792492 — Surrogate Endpoint (SUR): Bone mineral density
Study 23275593 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21984584 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 16501248 — Predictive Biomarker (PRD): PRDM2 mRNA
Genes: PRDM2; KMT8; RIZ
Study 16501248 — Predictive Biomarker (PRD): EHMT2 mRNA
Genes: EHMT2; BAT8; C6orf30; G9A; KMT1C; NG36
Study 10894313 — Surrogate Endpoint (SUR): Bone mineral density
Study 29518488 — Surrogate Endpoint (SUR): Blood pressure
Study 29518488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18622280 — Surrogate Endpoint (SUR): Serum creatinine
Study 16135476 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16135476 — Safety Biomarker (SAF): Interleukin 1
Study 16135476 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11812507 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11812507 — Surrogate Endpoint (SUR): Blood pressure
Study 11812507 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 10624328 — Surrogate Endpoint (SUR): Serum creatinine
Study 1935152 — Surrogate Endpoint (SUR): Serum sodium
Study 27804204 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26452988 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 17084252 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8302412 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30883516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27093702 — Surrogate Endpoint (SUR): Blood pressure