TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16505510 — Surrogate Endpoint (SUR): Blood pressure
Study 8418030 — Surrogate Endpoint (SUR): Blood pressure
Study 8418030 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20622033 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 12564659 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 1320131 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 24721127 — Surrogate Endpoint (SUR): Serum creatinine
Study 14500805 — Surrogate Endpoint (SUR): Bone mineral density
Study 14500805 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2666140 — Surrogate Endpoint (SUR): Blood pressure
Study 23799751 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18292453 — Surrogate Endpoint (SUR): Blood pressure
Study 16531162 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21091062 — Surrogate Endpoint (SUR): Blood pressure
Study 21091062 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12626972 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 8457236 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30893271 — Predictive Biomarker (PRD): CD101 mRNA
Genes: CD101; EWI101; IGSF2; V7
Study 29954403 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 25623883 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25623883 — Surrogate Endpoint (SUR): Blood pressure
Study 15998769 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15998769 — Surrogate Endpoint (SUR): Serum creatinine
Study 8602658 — Surrogate Endpoint (SUR): Blood pressure
Study 1777174 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7324943 — Surrogate Endpoint (SUR): Serum calcium
Study 31454197 — Predictive Biomarker (PRD): CPB1 mRNA
Genes: CPB1; CPB; PCPB
Study 23413781 — Surrogate Endpoint (SUR): Serum creatinine
Study 9620911 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 2668247 — Surrogate Endpoint (SUR): Serum creatinine
Study 324566 — Surrogate Endpoint (SUR): Blood pressure
Study 29415833 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29415833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29415833 — Safety Biomarker (SAF): IL-6 and IL-10
Study 23816726 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 29452603 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 16402604 — Surrogate Endpoint (SUR): Blood pressure
Study 8061263 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 22398345 — Surrogate Endpoint (SUR): Blood pressure
Study 9212478 — Predictive Biomarker (PRD): SRY mRNA
Genes: SRY; TDF
Study 30737889 — Surrogate Endpoint (SUR): Blood pressure
Study 29364091 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29364091 — Monitoring Biomarker (MOI): HBV DNA
Study 29364091 — Surrogate Endpoint (SUR): Serum creatinine
Study 10908213 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9156659 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7798818 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 24678979 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 24678979 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24678979 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31461862 — Surrogate Endpoint (SUR): Blood pressure
Study 20565953 — Surrogate Endpoint (SUR): Pathological complete response
Study 17407241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2008870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2008870 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23403068 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22000309 — Surrogate Endpoint (SUR): Blood pressure
Study 11422014 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 8536521 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 15236012 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26083700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19663929 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 18617745 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 12788888 — Predictive Biomarker (PRD): MENT mRNA
Genes: MENT; C1orf56; UNQ547/PRO1104
Study 12788888 — Surrogate Endpoint (SUR): Bone mineral density
Study 24629400 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24629400 — Surrogate Endpoint (SUR): Blood pressure
Study 17519714 — Surrogate Endpoint (SUR): Blood pressure
Study 25968007 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 14999200 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10705305 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8565536 — Surrogate Endpoint (SUR): Serum potassium
Study 8565536 — Surrogate Endpoint (SUR): Serum calcium
Study 1759835 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 23339040 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 11942472 — Surrogate Endpoint (SUR): Blood pressure
Study 2679288 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29411724 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 26367239 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 20846715 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20846715 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24260122 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 11566619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11566619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8059693 — Surrogate Endpoint (SUR): Blood pressure
Study 29121326 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 15273918 — Surrogate Endpoint (SUR): Bone mineral density
Study 11500195 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 21835280 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21835280 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 26881447 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 25919121 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 23650294 — Surrogate Endpoint (SUR): Blood pressure
Study 18222192 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 12675866 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12675866 — Surrogate Endpoint (SUR): Blood pressure
Study 10963287 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 29193563 — Surrogate Endpoint (SUR): Serum uric acid
Study 29193563 — Surrogate Endpoint (SUR): Blood pressure
Study 25020061 — Predictive Biomarker (PRD): ULK1 mRNA
Genes: ULK1; KIAA0722
Study 25020061 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 20864555 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 1336527 — Surrogate Endpoint (SUR): Blood pressure
Study 6518669 — Surrogate Endpoint (SUR): Blood pressure
Study 10369491 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 786694 — Surrogate Endpoint (SUR): Blood pressure
Study 31234234 — Predictive Biomarker (PRD): HMMR mRNA
Genes: HMMR; IHABP; RHAMM
Study 23937692 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 22781571 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 25483598 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 25483598 — Safety Biomarker (SAF): Th2 cell
Study 20068404 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 9694611 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25984891 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9794735 — Surrogate Endpoint (SUR): Blood pressure
Study 9794735 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31512365 — Surrogate Endpoint (SUR): Blood pressure
Study 22739747 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 19001830 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17024647 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7708266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7708266 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 30613020 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 30613020 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30613020 — Surrogate Endpoint (SUR): Blood pressure
Study 18505112 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31100534 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31100534 — Predictive Biomarker (PRD): GIPR mRNA
Genes: GIPR
Study 17906182 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16135576 — Surrogate Endpoint (SUR): Blood pressure
Study 10457271 — Surrogate Endpoint (SUR): Bone mineral density
Study 31298823 — Surrogate Endpoint (SUR): Blood pressure
Study 11137745 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11137745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7930741 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28303421 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 28167746 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21692235 — Predictive Biomarker (PRD): LNX1 mRNA
Genes: LNX1; LNX; PDZRN2; UNQ574/PRO1136
Study 9223109 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 21963834 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21963834 — Surrogate Endpoint (SUR): Blood pressure
Study 21937568 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 31297962 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30165522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12799102 — Surrogate Endpoint (SUR): Blood pressure
Study 10372237 — Surrogate Endpoint (SUR): Blood pressure
Study 1839161 — Surrogate Endpoint (SUR): Blood pressure
Study 24667908 — Surrogate Endpoint (SUR): Blood pressure
Study 22871128 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 2291867 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31199705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31199705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31199705 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 28575224 — Predictive Biomarker (PRD): DHCR7 mRNA
Genes: DHCR7; D7SR
Study 28575224 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 28575224 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 28575224 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28029540 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 24929023 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 24929023 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24929023 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22344504 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22344504 — Surrogate Endpoint (SUR): Serum creatinine
Study 9356038 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 7706591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31085097 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 26927446 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19602719 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 14734438 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24129613 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 24129613 — Predictive Biomarker (PRD): CD6 mRNA
Genes: CD6
Study 25199825 — Predictive Biomarker (PRD): DDN mRNA
Genes: DDN; KIAA0749
Study 2719760 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2719760 — Surrogate Endpoint (SUR): Blood pressure
Study 2719760 — Surrogate Endpoint (SUR): Serum potassium
Study 11054200 — Surrogate Endpoint (SUR): Blood pressure
Study 23291141 — Surrogate Endpoint (SUR): Pathological complete response
Study 15634033 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26426148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23735514 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 12728489 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 22219221 — Safety Biomarker (SAF): DRD3
Study 12474069 — Surrogate Endpoint (SUR): Serum calcium
Study 12474069 — Surrogate Endpoint (SUR): Blood pressure
Study 12474069 — Surrogate Endpoint (SUR): Bone mineral density
Study 2674028 — Surrogate Endpoint (SUR): Blood pressure
Study 20473910 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 20473910 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 26041481 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26041481 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23146365 — Surrogate Endpoint (SUR): Blood pressure
Study 15630501 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7586935 — Surrogate Endpoint (SUR): Blood pressure
Study 28642340 — Surrogate Endpoint (SUR): Blood pressure
Study 21659891 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 17933414 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12774016 — Safety Biomarker (SAF): Interleukin 12
Study 9357377 — Surrogate Endpoint (SUR): Blood pressure
Study 9357377 — Surrogate Endpoint (SUR): Serum potassium
Study 1588824 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 2862995 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24661672 — Predictive Biomarker (PRD): SPARCL1 mRNA
Genes: SPARCL1
Study 14512132 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 17312210 — Surrogate Endpoint (SUR): Blood pressure
Study 28960777 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28960777 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28960777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16525138 — Monitoring Biomarker (MOI): HBV DNA
Study 31382965 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 11575224 — Surrogate Endpoint (SUR): Blood pressure
Study 8269798 — Surrogate Endpoint (SUR): Blood pressure
Study 8269798 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31522180 — Surrogate Endpoint (SUR): Serum sodium
Study 18343739 — Predictive Biomarker (PRD): ACRC mRNA
Genes: GCNA; ACRC
Study 12726869 — Surrogate Endpoint (SUR): Blood pressure
Study 25144793 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17076857 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 17076857 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12679389 — Predictive Biomarker (PRD): TPM1 mRNA
Genes: TPM1; C15orf13; TMSA
Study 25558638 — Surrogate Endpoint (SUR): Blood pressure
Study 22479542 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22479542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 785959 — Surrogate Endpoint (SUR): Serum creatinine
Study 785959 — Safety Biomarker (SAF): Urinary total protein
Study 22698005 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22698005 — Predictive Biomarker (PRD): Epithelial cadherin
Genes: CDH1; CDHE; UVO
Study 17327342 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 15467218 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 10391259 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31440799 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study 28892656 — Safety Biomarker (SAF): miR-15a
Genes: MIR15A
Study 25789421 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 31390883 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 31390883 — Predictive Biomarker (PRD): LRP1 mRNA
Genes: LRP1; A2MR; APR
Study 29725828 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 5015036 — Surrogate Endpoint (SUR): Blood pressure
Study 12755932 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10629456 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24424781 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 17087785 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12800105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29458404 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 21831167 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27342222 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 11233387 — Surrogate Endpoint (SUR): Blood pressure
Study 11233387 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7838619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28267471 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25946654 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 25946654 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 25946654 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19505293 — Surrogate Endpoint (SUR): Blood pressure
Study 16622120 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29768290 — Surrogate Endpoint (SUR): Blood pressure
Study 22713720 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28025538 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 20202859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20202859 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 20202859 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16492404 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 7625467 — Predictive Biomarker (PRD): PTK7 mRNA
Genes: PTK7; CCK4
Study 30218286 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28515164 — Predictive Biomarker (PRD): SLC39A8 mRNA
Genes: SLC39A8; BIGM103; ZIP8; PP3105
Study 28515164 — Predictive Biomarker (PRD): SLC39A1 mRNA
Genes: SLC39A1; IRT1; ZIP1; ZIRTL; CGI-08; CGI-71
Study 25312998 — Predictive Biomarker (PRD): MPST mRNA
Genes: MPST; TST2
Study 23748441 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16705487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16705487 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9232361 — Surrogate Endpoint (SUR): Blood pressure
Study 21614411 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 12831624 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12831624 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 12831624 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 12831624 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28466679 — Surrogate Endpoint (SUR): Bone mineral density
Study 28466679 — Surrogate Endpoint (SUR): Serum calcium
Study 27428671 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27428671 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 27428671 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 27428671 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 21293163 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19267407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9269788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9269788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19263034 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9205013 — Surrogate Endpoint (SUR): Blood pressure
Study 26786000 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16444450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16444450 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11774859 — Surrogate Endpoint (SUR): Blood pressure
Study 8344693 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29752304 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 22005962 — Predictive Biomarker (PRD): SLMAP mRNA
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 18284400 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18284400 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 29055489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2