TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31022160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31022160 — Surrogate Endpoint (SUR): Blood pressure
Study 31022160 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24419562 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 24419562 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 9918907 — Surrogate Endpoint (SUR): Blood pressure
Study 20306476 — Surrogate Endpoint (SUR): Serum calcium
Study 10084467 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 9738692 — Surrogate Endpoint (SUR): Blood pressure
Study 20051692 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10225069 — Surrogate Endpoint (SUR): Blood pressure
Study 8952812 — Surrogate Endpoint (SUR): Blood pressure
Study 8519216 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31140940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21738622 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 12507707 — Surrogate Endpoint (SUR): Blood pressure
Study 31618540 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15277331 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 8301727 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23415171 — Surrogate Endpoint (SUR): Blood pressure
Study 16948481 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27757803 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11477202 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7978176 — Predictive Biomarker (PRD): NELFCD mRNA
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 23593327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20621562 — Surrogate Endpoint (SUR): Blood pressure
Study 24798767 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20362710 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20362710 — Surrogate Endpoint (SUR): Blood pressure
Study 8847861 — Surrogate Endpoint (SUR): Blood pressure
Study 1562095 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 6320945 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27042750 — Surrogate Endpoint (SUR): Bone mineral density
Study 24201089 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24201089 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24201089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24201089 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22454414 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12490735 — Predictive Biomarker (PRD): Hormone receptor
Study 1938279 — Surrogate Endpoint (SUR): Blood pressure
Study 28360116 — Safety Biomarker (SAF): MTHFR
Study 24038736 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 22004512 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 27865566 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 15309445 — Predictive Biomarker (PRD): OGG1 mRNA
Genes: OGG1; MMH; MUTM; OGH1
Study 2318105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12118266 — Surrogate Endpoint (SUR): Blood pressure
Study 19231545 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 19231545 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 15179026 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 16218198 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 10471456 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18535115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11103752 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26062785 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 24940052 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 30844053 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 30844053 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23184565 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2949585 — Surrogate Endpoint (SUR): Blood pressure
Study 29624463 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19432501 — Surrogate Endpoint (SUR): Blood pressure
Study 9745150 — Surrogate Endpoint (SUR): Blood pressure
Study 11403539 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15840681 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 2112184 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 100129 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21910947 — Surrogate Endpoint (SUR): Blood pressure
Study 9506749 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30169980 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 30987551 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30987551 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30987551 — Safety Biomarker (SAF): Reactive oxygen species
Study 26802793 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 25942341 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7719894 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7719894 — Surrogate Endpoint (SUR): Serum potassium
Study 7719894 — Surrogate Endpoint (SUR): Blood pressure
Study 26955912 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11209104 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 3398697 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 31920008 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24797760 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24192751 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 7769049 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 19285833 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19285833 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11463772 — Surrogate Endpoint (SUR): Blood pressure
Study 9879155 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 31028038 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 12002198 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11422108 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 11422108 — Surrogate Endpoint (SUR): Bone mineral density
Study 28645949 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28645949 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21445287 — Predictive Biomarker (PRD): SELENOW mRNA
Genes: SELENOW; SELW; SEPW1
Study 19419670 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11509081 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 26834211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22176998 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21519359 — Surrogate Endpoint (SUR): Bone mineral density
Study 21519359 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16278367 — Surrogate Endpoint (SUR): Serum testosterone
Study 12709719 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 23043563 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9737475 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7921469 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 23230135 — Predictive Biomarker (PRD): NCOA3 mRNA
Genes: NCOA3; AIB1; BHLHE42; RAC3; TRAM1
Study 23230135 — Predictive Biomarker (PRD): PAX2 mRNA
Genes: PAX2
Study 30712740 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 1357152 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1357152 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 29566934 — Surrogate Endpoint (SUR): Serum sodium
Study 29566934 — Surrogate Endpoint (SUR): Blood pressure
Study 26272586 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 24819761 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 11801426 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 15374060 — Surrogate Endpoint (SUR): Blood pressure
Study 30753625 — Surrogate Endpoint (SUR): Blood pressure
Study 18987053 — Surrogate Endpoint (SUR): Blood pressure
Study 8616760 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 22708917 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 10364997 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1911428 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1911428 — Surrogate Endpoint (SUR): Serum testosterone
Study 29099947 — Surrogate Endpoint (SUR): Serum calcium
Study 22776430 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28398692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9042130 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2835964 — Surrogate Endpoint (SUR): Blood pressure
Study 25645567 — Surrogate Endpoint (SUR): Blood pressure
Study 25645567 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25645567 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23870798 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23870798 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18855244 — Surrogate Endpoint (SUR): Blood pressure
Study 29968686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29968686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22953754 — Surrogate Endpoint (SUR): Blood pressure
Study 25277459 — Safety Biomarker (SAF): Reactive oxygen species
Study 19201295 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9536833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2397544 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 23787550 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29317896 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 29317896 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 23590265 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 21149654 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 18348888 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18348888 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 10866914 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 2876573 — Surrogate Endpoint (SUR): Serum uric acid
Study 2876573 — Surrogate Endpoint (SUR): Blood pressure
Study 22622452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8773915 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 8773915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8773915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6560420 — Surrogate Endpoint (SUR): Blood pressure
Study 20167702 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 20167702 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20167702 — Surrogate Endpoint (SUR): Serum creatinine
Study 7655833 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24588789 — Surrogate Endpoint (SUR): Blood pressure
Study 8730431 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 27068631 — Surrogate Endpoint (SUR): Serum creatinine
Study 27068631 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17916078 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10322043 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 9086318 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9086318 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9086318 — Surrogate Endpoint (SUR): Blood pressure
Study 25012240 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25012240 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2019135 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31841599 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31841599 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 21211560 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18753466 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11353965 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11353965 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 31300879 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31300879 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 18458163 — Surrogate Endpoint (SUR): Blood pressure
Study 11191537 — Surrogate Endpoint (SUR): Blood pressure
Study 21664286 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19403950 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 12401850 — Surrogate Endpoint (SUR): Serum creatinine
Study 9832182 — Surrogate Endpoint (SUR): Blood pressure
Study 15233837 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9241548 — Surrogate Endpoint (SUR): Serum calcium
Study 9241548 — Surrogate Endpoint (SUR): Serum sodium
Study 24806568 — Surrogate Endpoint (SUR): Blood pressure
Study 25810595 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29526457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29526457 — Safety Biomarker (SAF): Interleukin 1
Study 10606935 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 1501967 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 27143319 — Surrogate Endpoint (SUR): Blood pressure
Study 23726630 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14759617 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 9778666 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28342967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12816748 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 20629630 — Surrogate Endpoint (SUR): Bone mineral density
Study 31675621 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 23895631 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19153263 — Surrogate Endpoint (SUR): Blood pressure
Study 12684362 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 30109404 — Safety Biomarker (SAF): Hyaluronic acid
Study 18751689 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17900462 — Predictive Biomarker (PRD): ADCY10 mRNA
Genes: ADCY10; SAC
Study 15006018 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 27113485 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 27113485 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 27113485 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24168514 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18343261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16299878 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 12572927 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8521118 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 30969260 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29716784 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 19641360 — Surrogate Endpoint (SUR): Serum sodium
Study 17469136 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 17469136 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 17469136 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 26921523 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 26921523 — Predictive Biomarker (PRD): ITFG1 mRNA
Genes: ITFG1; LNKN-1; TIP; CDA08
Study 25117466 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18019394 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 22673937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22673937 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22673937 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17634479 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17634479 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17634479 — Predictive Biomarker (PRD): Hormone receptor
Study 17634479 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22398088 — Surrogate Endpoint (SUR): Bone mineral density
Study 20196149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20196149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9348446 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 15081453 — Surrogate Endpoint (SUR): Blood pressure
Study 19722799 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 11572292 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 9280178 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9280178 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8393884 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3089519 — Surrogate Endpoint (SUR): Blood pressure
Study 16298441 — Surrogate Endpoint (SUR): Serum creatinine
Study 16298441 — Surrogate Endpoint (SUR): Blood pressure
Study 9109757 — Predictive Biomarker (PRD): INVS mRNA
Genes: INVS; INV; NPHP2
Study 25540298 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 12571159 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8174967 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8174967 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 25398288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25398288 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17577462 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12542882 — Surrogate Endpoint (SUR): Serum sodium
Study 31301293 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31301293 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25329681 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7539635 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7539635 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 7539635 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18563062 — Surrogate Endpoint (SUR): Blood pressure
Study 11117247 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 920841 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 920841 — Surrogate Endpoint (SUR): Blood pressure
Study 23891363 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23891363 — Surrogate Endpoint (SUR): Serum creatinine
Study 2008110 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22428485 — Surrogate Endpoint (SUR): Blood pressure
Study 17312229 — Surrogate Endpoint (SUR): Blood pressure
Study 7906384 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1982648 — Predictive Biomarker (PRD): EHF mRNA
Genes: EHF; ESE3; ESE3B; ESEJ
Study 9231834 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9231834 — Surrogate Endpoint (SUR): Blood pressure
Study 9231834 — Surrogate Endpoint (SUR): Serum potassium
Study 23711620 — Surrogate Endpoint (SUR): Bone mineral density
Study 22052452 — Surrogate Endpoint (SUR): Bone mineral density
Study 17452893 — Surrogate Endpoint (SUR): Blood pressure
Study 27059671 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 17548672 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17548672 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 17548672 — Safety Biomarker (SAF): Reactive oxygen species
Study 9578817 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 193359 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15266206 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10667721 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27626492 — Predictive Biomarker (PRD): PROX1 mRNA
Genes: PROX1
Study 27626492 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 25024177 — Surrogate Endpoint (SUR): Blood pressure
Study 18512085 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 16128369 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26170625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26170625 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26170625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9457935 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG