TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03014232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03263559 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01292278 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT00098566 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03871114 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT00124280 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00124280 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00199979 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00848640 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT00119678 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01036659 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02704247 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00453414 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04664725 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT04045899 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02229734 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03181113 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00047658 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02671513 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT00321126 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02931643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03089385 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03267485 — Predictive Biomarker (PRD): TET1 mRNA
Genes: TET1; CXXC6; KIAA1676; LCX
Study NCT01664000 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01664000 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study NCT01664000 — Predictive Biomarker (PRD): BBC3 mRNA
Genes: BBC3; PUMA
Study NCT01679171 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT00827138 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00827138 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00827138 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00827138 — Predictive Biomarker (PRD): LYN mRNA
Genes: LYN; JTK8
Study NCT00827138 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT03692416 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT00946218 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study NCT00439738 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04411563 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04411563 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT04411563 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): miR-124
Study NCT04411563 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study NCT04411563 — Predictive Biomarker (PRD): miR-19a
Genes: MIR19A
Study NCT04411563 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study NCT04411563 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT04411563 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study NCT04411563 — Safety Biomarker (SAF): miR-9
Study NCT04453735 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study NCT02559492 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT02559492 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT02559492 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02466646 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT00367679 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00029328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03693560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03693560 — Safety Biomarker (SAF): Interleukin 1
Study NCT01030666 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT02764541 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01990261 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01806662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00161590 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study NCT03198689 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00483756 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study NCT01730248 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01837459 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01837459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03135405 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04339309 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT03904368 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02658383 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02108925 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01725269 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03749980 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT03749980 — Predictive Biomarker (PRD): FLCN mRNA
Genes: FLCN; BHD
Study NCT03454165 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01495884 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01596062 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT03072602 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study NCT02908542 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study NCT00991679 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study NCT00991679 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT00991679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study NCT00991679 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study NCT02342834 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03345056 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04503408 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01769937 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02453815 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00325078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03246828 — Predictive Biomarker (PRD): HNF4A mRNA
Genes: HNF4A; HNF4; NR2A1; TCF14
Study NCT03767270 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT03455673 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00977509 — Predictive Biomarker (PRD): SH3PXD2A mRNA
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study NCT03346330 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT00990028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00990028 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02189902 — Surrogate Endpoint (SUR): Serum calcium
Study NCT03244059 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study NCT00582556 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT00582556 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03919643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03919643 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT03919643 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study NCT00700856 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04953871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04587128 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04587128 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02159807 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00303368 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00894959 — Predictive Biomarker (PRD): TTPA mRNA
Genes: TTPA; TPP1
Study NCT00175383 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03129308 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00450944 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00450944 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT00008190 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02080533 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02080533 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02080533 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT02080533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02080533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03969784 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03969784 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT03180814 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03374280 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02646293 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01970176 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study NCT03345186 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00010231 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT03554044 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03554044 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00123058 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01185314 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01185314 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02109016 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02109016 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03328884 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01097031 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01120743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02796755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01697540 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01697540 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study NCT02495571 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00179205 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01327313 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT01510535 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02536287 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT03844243 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT01196702 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT00982761 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01964157 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT01964157 — Predictive Biomarker (PRD): SLC34A2 mRNA
Genes: SLC34A2
Study NCT01964157 — Predictive Biomarker (PRD): CD74 mRNA
Genes: CD74; DHLAG
Study NCT01964157 — Predictive Biomarker (PRD): SDC4 mRNA
Genes: SDC4
Study NCT01964157 — Predictive Biomarker (PRD): LRIG3 mRNA
Genes: LRIG3; LIG3; UNQ287/PRO326/PRO335
Study NCT00455091 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04150926 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03359018 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02382484 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05731089 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05731089 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03806426 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT00393419 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00393419 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01648556 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT00313066 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study NCT00313066 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT00570726 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00570024 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03844711 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03816540 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04605705 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04605705 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03627039 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03729323 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00493181 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study NCT00191373 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01488253 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT04405466 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03002974 — Safety Biomarker (SAF): Interleukin 1
Study NCT06103214 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT00682058 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00754156 — Predictive Biomarker (PRD): ABRA mRNA
Genes: ABRA
Study NCT03921996 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03719794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03719794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01546792 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02093455 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00831818 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT03360864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02525003 — Surrogate Endpoint (SUR): Serum calcium
Study NCT03798288 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT03074214 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT00435045 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04311593 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04311593 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04311593 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02561663 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04355585 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study NCT04667026 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03294577 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT02707458 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04301427 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02316509 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02316509 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02316509 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00146601 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00651196 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04121078 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT04121078 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study NCT00260364 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00260364 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03483129 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05567523 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02787239 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02924701 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT02535364 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01384292 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT00100360 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT03065829 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00872183 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00872183 — Safety Biomarker (SAF): BDNF
Study NCT01675089 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02452086 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02452086 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00937222 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01452646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03234153 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT00971685 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00971685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00971685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00971685 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01814995 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00079144 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04562298 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT00054132 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00823641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01309828 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03323788 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study NCT03246841 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00454207 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04182438 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02553135 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study NCT01625286 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT01625286 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03883074 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04813913 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04813913 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03152994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03152994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03152994 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT02965157 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT01551745 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03884465 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03884465 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00299273 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00827359 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study NCT01357811 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1