TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16607077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11025358 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 21444883 — Surrogate Endpoint (SUR): Blood pressure
Study 19429451 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 19429451 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12777437 — Surrogate Endpoint (SUR): Blood pressure
Study 14587651 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14587651 — Surrogate Endpoint (SUR): Blood pressure
Study 23939544 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17387446 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9060541 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9806669 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 31592939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26781763 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 25401501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22863643 — Surrogate Endpoint (SUR): Blood pressure
Study 31088784 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 20625738 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12794408 — Surrogate Endpoint (SUR): Blood pressure
Study 23774460 — Surrogate Endpoint (SUR): Serum creatinine
Study 20736298 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15836977 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 26502371 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 25329228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20014183 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 18550438 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 12154423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12154423 — Safety Biomarker (SAF): IL-6 and IL-10
Study 7536072 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7536072 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24549027 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 16840576 — Surrogate Endpoint (SUR): Blood pressure
Study 16840576 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10879665 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3014925 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 18313286 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18313286 — Surrogate Endpoint (SUR): Blood pressure
Study 12447291 — Surrogate Endpoint (SUR): Blood pressure
Study 17543201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25617625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25617625 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 16526986 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10920581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29298160 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29298160 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22152078 — Surrogate Endpoint (SUR): Blood pressure
Study 20473861 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29241359 — Predictive Biomarker (PRD): CRHBP mRNA
Genes: CRHBP; CRFBP
Study 26925867 — Surrogate Endpoint (SUR): Blood pressure
Study 17077344 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 17077344 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 16222402 — Surrogate Endpoint (SUR): Bone mineral density
Study 12174698 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 27821673 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 31434507 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28288972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28288972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28288972 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16336993 — Surrogate Endpoint (SUR): Bone mineral density
Study 8511727 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18587715 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15752376 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 3895545 — Predictive Biomarker (PRD): ACTA1 mRNA
Genes: ACTA1; ACTA
Study 20484012 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 9015418 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6345161 — Surrogate Endpoint (SUR): Blood pressure
Study 24998117 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 14611917 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 8993768 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 1535505 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 28683796 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 16573707 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12773645 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19033823 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8887038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8887038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31901082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11740295 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11740295 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 25089351 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25089351 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17078981 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 9454229 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31648505 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 31648505 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 30278560 — Surrogate Endpoint (SUR): Blood pressure
Study 28393775 — Surrogate Endpoint (SUR): Blood pressure
Study 26152838 — Surrogate Endpoint (SUR): Blood pressure
Study 31838498 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17370487 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 12740311 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6135989 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27555178 — Surrogate Endpoint (SUR): Blood pressure
Study 18684843 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 18684843 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18684843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18684843 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 8976353 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25306809 — Surrogate Endpoint (SUR): Serum sodium
Study 21251359 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19898698 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27009938 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 11233879 — Surrogate Endpoint (SUR): Serum creatinine
Study 9031957 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 7838644 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 699788 — Surrogate Endpoint (SUR): Serum potassium
Study 30633058 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30633058 — Surrogate Endpoint (SUR): Blood pressure
Study 31223480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31223480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23168366 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18379357 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18379357 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14673218 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 14673218 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 20464263 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 14685040 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 29354932 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 20461068 — Monitoring Biomarker (MOI): HBV DNA
Study 30153782 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 30153782 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 30153782 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 15799079 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 7707111 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 7707111 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11091188 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 11091188 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11091188 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 2895171 — Surrogate Endpoint (SUR): Blood pressure
Study 31570566 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25456710 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25456710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25456710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20167117 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 12834362 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12834362 — Surrogate Endpoint (SUR): Blood pressure
Study 31631029 — Surrogate Endpoint (SUR): Blood pressure
Study 29917190 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29917190 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26833462 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study 20975266 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18476420 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10024334 — Surrogate Endpoint (SUR): Blood pressure
Study 28348190 — Predictive Biomarker (PRD): TP53INP1 mRNA
Genes: TP53INP1; P53DINP1; SIP
Study 20626736 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 20626736 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 17052775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17052775 — Safety Biomarker (SAF): MTHFR
Study 30096354 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23072926 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 23072926 — Safety Biomarker (SAF): Reactive oxygen species
Study 9554816 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9593458 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2664628 — Surrogate Endpoint (SUR): Blood pressure
Study 30916203 — Surrogate Endpoint (SUR): Blood pressure
Study 23331443 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23331443 — Surrogate Endpoint (SUR): Blood pressure
Study 21273355 — Predictive Biomarker (PRD): SCARA3 mRNA
Genes: SCARA3; CSR
Study 19671411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19671411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11705848 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 11705848 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9146313 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20435231 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 19863407 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8365971 — Surrogate Endpoint (SUR): Plasma ammonia
Study 8365971 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22735495 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28242714 — Surrogate Endpoint (SUR): Blood pressure
Study 25968576 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25968576 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 17969887 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 17969887 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17969887 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 17969887 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 24067081 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26258821 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 22160369 — Predictive Biomarker (PRD): PRDX1 mRNA
Genes: PRDX1; PAGA; PAGB; TDPX2
Study 22160369 — Predictive Biomarker (PRD): PRDX2 mRNA
Genes: PRDX2; NKEFB; TDPX1
Study 9142510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9142510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7944932 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17161050 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17161050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21982652 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30845731 — Surrogate Endpoint (SUR): Serum uric acid
Study 11224816 — Surrogate Endpoint (SUR): Blood pressure
Study 12235693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7591530 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2196085 — Surrogate Endpoint (SUR): Blood pressure
Study 2196085 — Surrogate Endpoint (SUR): Serum creatinine
Study 31155138 — Surrogate Endpoint (SUR): Blood pressure
Study 28770893 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 28770893 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 17261662 — Surrogate Endpoint (SUR): Blood pressure
Study 8798046 — Surrogate Endpoint (SUR): Blood pressure
Study 30944040 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 20401662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1431013 — Surrogate Endpoint (SUR): Blood pressure
Study 21802266 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21802266 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 20430934 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20430934 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 18557690 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 15872036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15872036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15872036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10697623 — Safety Biomarker (SAF): 51Cr-EDTA
Study 26468123 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 26468123 — Predictive Biomarker (PRD): GPX3 mRNA
Genes: GPX3; GPXP
Study 23926583 — Surrogate Endpoint (SUR): Probing pocket depth
Study 9710685 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 9710685 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 2499150 — Surrogate Endpoint (SUR): Serum testosterone
Study 25326831 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23281041 — Surrogate Endpoint (SUR): Bone mineral density
Study 1666179 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1666179 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 23816513 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9393518 — Surrogate Endpoint (SUR): Blood pressure
Study 15552635 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 29366988 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28644348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26564807 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 12560759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8407387 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24174172 — Surrogate Endpoint (SUR): Blood pressure
Study 15156070 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 3290356 — Surrogate Endpoint (SUR): Blood pressure
Study 25761552 — Surrogate Endpoint (SUR): Serum calcium
Study 15478388 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 15478388 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 15478388 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15280530 — Surrogate Endpoint (SUR): Serum creatinine
Study 10572674 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 20709866 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15878496 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 7599449 — Surrogate Endpoint (SUR): Bone mineral density
Study 12765424 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12765424 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 12765424 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10648040 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 3333017 — Surrogate Endpoint (SUR): Serum calcium
Study 29242350 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18443191 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18443191 — Surrogate Endpoint (SUR): Blood pressure
Study 11789260 — Safety Biomarker (SAF): Hyaluronic acid
Study 29313286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18713505 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15007396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15007396 — Surrogate Endpoint (SUR): Blood pressure
Study 27389186 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 10913814 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18564698 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 19825916 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16040619 — Surrogate Endpoint (SUR): Blood pressure
Study 7977730 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 16832680 — Surrogate Endpoint (SUR): Serum creatinine
Study 18848109 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15747447 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 9856715 — Surrogate Endpoint (SUR): Blood pressure
Study 8390232 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8390232 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31203233 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 31203233 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 31203233 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 30401004 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30401004 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 22395643 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 22395643 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 16730335 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 16226614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6421243 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 16931506 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 7505351 — Surrogate Endpoint (SUR): Blood pressure
Study 3100466 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T