TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12023684 — Surrogate Endpoint (SUR): Blood pressure
Study 31240591 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 31240591 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8406151 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 27173100 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 24997182 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12767566 — Surrogate Endpoint (SUR): Blood pressure
Study 10877197 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8892714 — Surrogate Endpoint (SUR): Bone mineral density
Study 8892714 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8892714 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21636735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21636735 — Safety Biomarker (SAF): Reactive oxygen species
Study 21636735 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1255322 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24941787 — Surrogate Endpoint (SUR): Blood pressure
Study 18206569 — Surrogate Endpoint (SUR): Bone mineral density
Study 7876659 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 2227816 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15507062 — Surrogate Endpoint (SUR): Blood pressure
Study 9722036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31206301 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 19951602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7844605 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25400681 — Surrogate Endpoint (SUR): Blood pressure
Study 17940860 — Surrogate Endpoint (SUR): Blood pressure
Study 17940860 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 1366265 — Surrogate Endpoint (SUR): Blood pressure
Study 1366265 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3888836 — Surrogate Endpoint (SUR): Blood pressure
Study 24246407 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 22124042 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15389231 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15389231 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25664602 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23388208 — Predictive Biomarker (PRD): RTN1 mRNA
Genes: RTN1; NSP
Study 28126360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28126360 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21429452 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 19479183 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19479183 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 19479183 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 19479183 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 19479183 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 19479183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19479183 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19479183 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 9745404 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 9745404 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 21982663 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30914464 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 22608783 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22608783 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 10638770 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10638770 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23286246 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19480654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19480654 — Surrogate Endpoint (SUR): Bone mineral density
Study 12536625 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29882635 — Surrogate Endpoint (SUR): Blood pressure
Study 29952159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29952159 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 29952159 — Predictive Biomarker (PRD): PRKAA1 mRNA
Genes: PRKAA1; AMPK1
Study 29952159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22098272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22098272 — Safety Biomarker (SAF): Interleukin 1
Study 22098272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21286411 — Surrogate Endpoint (SUR): Blood pressure
Study 1651993 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 1443864 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18450803 — Surrogate Endpoint (SUR): Serum creatinine
Study 7495344 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26154851 — Surrogate Endpoint (SUR): Blood pressure
Study 17379122 — Surrogate Endpoint (SUR): Blood pressure
Study 15613678 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 15613678 — Surrogate Endpoint (SUR): Bone mineral density
Study 11875051 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 11875051 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 11875051 — Predictive Biomarker (PRD): MMP12 mRNA
Genes: MMP12; HME
Study 8669887 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 475947 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 30915462 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30915462 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 30915462 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23414745 — Surrogate Endpoint (SUR): Blood pressure
Study 16800964 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16800964 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12240665 — Surrogate Endpoint (SUR): Blood pressure
Study 8305640 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30725015 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 7495392 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 27289009 — Surrogate Endpoint (SUR): Blood pressure
Study 12459934 — Surrogate Endpoint (SUR): Bone mineral density
Study 27593709 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 20479948 — Surrogate Endpoint (SUR): Blood pressure
Study 20479948 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15925862 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 10516393 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10516393 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 1934440 — Surrogate Endpoint (SUR): Blood pressure
Study 6366135 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18272912 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18272912 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18272912 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9531231 — Surrogate Endpoint (SUR): Bone mineral density
Study 30818931 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17490918 — Surrogate Endpoint (SUR): Blood pressure
Study 11524308 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 27057866 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 27057866 — Surrogate Endpoint (SUR): Blood pressure
Study 19090407 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 16632022 — Surrogate Endpoint (SUR): Blood pressure
Study 9387731 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 2991478 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 30010061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20577119 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20577119 — Predictive Biomarker (PRD): SCNN1A mRNA
Genes: SCNN1A; SCNN1
Study 2551622 — Surrogate Endpoint (SUR): Blood pressure
Study 31812289 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23547848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23547848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10986540 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10986540 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25588664 — Surrogate Endpoint (SUR): Blood pressure
Study 25397825 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 22915053 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22915053 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20860546 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12444307 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6107057 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28969715 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24029871 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15187504 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10937036 — Surrogate Endpoint (SUR): Blood pressure
Study 10937036 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2517718 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 2517718 — Surrogate Endpoint (SUR): Blood pressure
Study 24862395 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7625348 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27922453 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23079864 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 23079864 — Safety Biomarker (SAF): Reactive oxygen species
Study 23079864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21646646 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19888785 — Surrogate Endpoint (SUR): Blood pressure
Study 16920896 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16920896 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 8114057 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8114057 — Surrogate Endpoint (SUR): Blood pressure
Study 2951019 — Surrogate Endpoint (SUR): Blood pressure
Study 29450827 — Predictive Biomarker (PRD): Hormone receptor
Study 29450827 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22851563 — Predictive Biomarker (PRD): CRLF2 mRNA
Genes: CRLF2; CRL2; ILXR; TSLPR
Study 22851563 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 22851563 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 22851563 — Predictive Biomarker (PRD): PAX5 mRNA
Genes: PAX5
Study 22851563 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 22851563 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 22851563 — Predictive Biomarker (PRD): BTG1 mRNA
Genes: BTG1
Study 22851563 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 22851563 — Predictive Biomarker (PRD): P2RY8 mRNA
Genes: P2RY8
Study 19186329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19186329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19186329 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12606734 — Monitoring Biomarker (MOI): HBV DNA
Study 30347425 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23104856 — Surrogate Endpoint (SUR): Blood pressure
Study 10602891 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 10602891 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24103528 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21438171 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31106835 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19864407 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 15856361 — Surrogate Endpoint (SUR): Serum testosterone
Study 15856361 — Surrogate Endpoint (SUR): Bone mineral density
Study 10482176 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7661176 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7661176 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 25122430 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 8590551 — Surrogate Endpoint (SUR): Blood pressure
Study 20368909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16044002 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10622646 — Surrogate Endpoint (SUR): Blood pressure
Study 8620717 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8620717 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 6257941 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 19879035 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1403033 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25660356 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20525942 — Predictive Biomarker (PRD): NE
Study 20573584 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study 21545398 — Surrogate Endpoint (SUR): Blood pressure
Study 11850304 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9988956 — Surrogate Endpoint (SUR): Blood pressure
Study 31707634 — Surrogate Endpoint (SUR): Blood pressure
Study 25857500 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14971716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26928677 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 21796252 — Surrogate Endpoint (SUR): Blood pressure
Study 29661196 — Surrogate Endpoint (SUR): Blood pressure
Study 28478972 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 28478972 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 16859226 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 16859226 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10389044 — Predictive Biomarker (PRD): SMC2 mRNA
Genes: SMC2; CAPE; SMC2L1; PRO0324
Study 8912804 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26378561 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23283370 — Surrogate Endpoint (SUR): Bone mineral density
Study 9626919 — Surrogate Endpoint (SUR): Blood pressure
Study 7532742 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2894747 — Surrogate Endpoint (SUR): Blood pressure
Study 6712450 — Surrogate Endpoint (SUR): Blood pressure
Study 9792282 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9792282 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 319326 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 319326 — Surrogate Endpoint (SUR): Blood pressure
Study 16594930 — Surrogate Endpoint (SUR): Bone mineral density
Study 3390997 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8256213 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24773263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19569965 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19569965 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19569965 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19569965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17289576 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 15356502 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 12195694 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12195694 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2808261 — Surrogate Endpoint (SUR): Blood pressure
Study 27533964 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27533964 — Surrogate Endpoint (SUR): Blood pressure
Study 21332798 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15164330 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10676671 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12840090 — Surrogate Endpoint (SUR): Serum creatinine
Study 8712092 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11095473 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 25753488 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27406165 — Surrogate Endpoint (SUR): Blood pressure
Study 16213286 — Surrogate Endpoint (SUR): Serum creatinine
Study 6337285 — Surrogate Endpoint (SUR): Blood pressure
Study 25095656 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 25095656 — Surrogate Endpoint (SUR): Blood pressure
Study 25095656 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12096825 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31331552 — Surrogate Endpoint (SUR): Blood pressure
Study 27653670 — Surrogate Endpoint (SUR): Blood pressure
Study 25350366 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24332919 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24332919 — Surrogate Endpoint (SUR): Serum creatinine
Study 24332919 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17007855 — Predictive Biomarker (PRD): HSPA2 mRNA
Genes: HSPA2
Study 15096570 — Safety Biomarker (SAF): MTHFR
Study 15096570 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21627686 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 21627686 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9470829 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7895954 — Surrogate Endpoint (SUR): Blood pressure
Study 12783047 — Surrogate Endpoint (SUR): Blood pressure
Study 3758239 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28757316 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 12439841 — Surrogate Endpoint (SUR): Serum creatinine
Study 8229755 — Surrogate Endpoint (SUR): Blood pressure
Study 30246320 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 10493325 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7495583 — Surrogate Endpoint (SUR): Serum potassium
Study 28560519 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24465617 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15083365 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 11786110 — Surrogate Endpoint (SUR): Blood pressure
Study 11786110 — Surrogate Endpoint (SUR): Serum calcium
Study 22480515 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 22480515 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22480515 — Surrogate Endpoint (SUR): Blood pressure
Study 19353750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10466475 — Surrogate Endpoint (SUR): Blood pressure
Study 10466475 — Surrogate Endpoint (SUR): Serum uric acid
Study 2192585 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2192585 — Surrogate Endpoint (SUR): Blood pressure
Study 21624736 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 2297461 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11899582 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1