TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1518433 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 1518433 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 30007559 — Surrogate Endpoint (SUR): Blood pressure
Study 24343353 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 8869897 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 6655288 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29066841 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29066841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21791651 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16421461 — Safety Biomarker (SAF): DRD3
Study 16791717 — Surrogate Endpoint (SUR): Blood pressure
Study 10549447 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8896646 — Surrogate Endpoint (SUR): Blood pressure
Study 1725028 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29320971 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 29320971 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 24792382 — Predictive Biomarker (PRD): ALLC mRNA
Genes: ALLC
Study 15812738 — Surrogate Endpoint (SUR): Blood pressure
Study 1760824 — Surrogate Endpoint (SUR): Blood pressure
Study 31767518 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 31767518 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31767518 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29130954 — Surrogate Endpoint (SUR): Serum sodium
Study 19720909 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 11443156 — Predictive Biomarker (PRD): Hormone receptor
Study 9875631 — Monitoring Biomarker (MOI): HBV DNA
Study 2730280 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 28349250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28349250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23296629 — Monitoring Biomarker (MOI): Procalcitonin
Study 23296629 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 23296629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21955225 — Surrogate Endpoint (SUR): Blood pressure
Study 19393142 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 16289171 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 16372578 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17655695 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16338252 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 16338252 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16338252 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17055561 — Surrogate Endpoint (SUR): Blood pressure
Study 15475599 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10445557 — Monitoring Biomarker (MOI): HBV DNA
Study 8695970 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 8695970 — Surrogate Endpoint (SUR): Bone mineral density
Study 8695970 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2392980 — Surrogate Endpoint (SUR): Blood pressure
Study 31087185 — Surrogate Endpoint (SUR): Bone mineral density
Study 22658571 — Surrogate Endpoint (SUR): Blood pressure
Study 22136279 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 22136279 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22136279 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 22136279 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22136279 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 17347071 — Surrogate Endpoint (SUR): Blood pressure
Study 7741850 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16669842 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2996342 — Surrogate Endpoint (SUR): Serum creatinine
Study 18095949 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2870533 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 23078878 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18669816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28759129 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28759129 — Surrogate Endpoint (SUR): Blood pressure
Study 28759129 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20519876 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20519876 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17118684 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11004033 — Surrogate Endpoint (SUR): Blood pressure
Study 27575565 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15657223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25701454 — Surrogate Endpoint (SUR): Blood pressure
Study 25701454 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23225026 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17761356 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 8743519 — Surrogate Endpoint (SUR): Blood pressure
Study 9375319 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 1554114 — Surrogate Endpoint (SUR): Blood pressure
Study 25140908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2124027 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7004624 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31778314 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 15118486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31692870 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31692870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26423732 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 26423732 — Predictive Biomarker (PRD): ARNT mRNA
Genes: ARNT; BHLHE2
Study 26423732 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 26423732 — Predictive Biomarker (PRD): JUN mRNA
Genes: JUN
Study 26423732 — Predictive Biomarker (PRD): NFAM1 mRNA
Genes: NFAM1; CNAIP
Study 26423732 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 26423732 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study 1648849 — Surrogate Endpoint (SUR): Serum calcium
Study 29018989 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17581200 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26918815 — Surrogate Endpoint (SUR): Bone mineral density
Study 26918815 — Surrogate Endpoint (SUR): Blood pressure
Study 22789310 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12970329 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12970329 — Safety Biomarker (SAF): Reactive oxygen species
Study 9370111 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 1283591 — Surrogate Endpoint (SUR): Blood pressure
Study 1283591 — Surrogate Endpoint (SUR): Serum creatinine
Study 2691476 — Surrogate Endpoint (SUR): Serum creatinine
Study 25504487 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 23779114 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19845513 — Surrogate Endpoint (SUR): Blood pressure
Study 29797519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24257725 — Surrogate Endpoint (SUR): Blood pressure
Study 18172059 — Surrogate Endpoint (SUR): Blood pressure
Study 31884075 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31884075 — Surrogate Endpoint (SUR): Blood pressure
Study 26137956 — Safety Biomarker (SAF): Reactive oxygen species
Study 17584058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29748349 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 29748349 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27537209 — Predictive Biomarker (PRD): DDN mRNA
Genes: DDN; KIAA0749
Study 19723080 — Surrogate Endpoint (SUR): Blood pressure
Study 16951956 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 11559545 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8152348 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8152348 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28836493 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 26633830 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 30126028 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9733365 — Surrogate Endpoint (SUR): Blood pressure
Study 29726939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22840987 — Safety Biomarker (SAF): Hyaluronic acid
Study 15715686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15715686 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8672354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29310899 — Surrogate Endpoint (SUR): Bone mineral density
Study 20145598 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 7840079 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 29996800 — Surrogate Endpoint (SUR): Serum creatinine
Study 22130403 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 20442386 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18403672 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8985076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8985076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8501777 — Surrogate Endpoint (SUR): Urinary oxalate
Study 25280032 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17369518 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 9988543 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7859244 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7859244 — Surrogate Endpoint (SUR): Blood pressure
Study 23481908 — Surrogate Endpoint (SUR): Blood pressure
Study 16864741 — Surrogate Endpoint (SUR): Blood pressure
Study 12588772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1770275 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 25148839 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25148839 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 25148839 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25148839 — Surrogate Endpoint (SUR): Blood pressure
Study 16189630 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16189630 — Surrogate Endpoint (SUR): Serum creatinine
Study 12202465 — Surrogate Endpoint (SUR): Bone mineral density
Study 9036798 — Surrogate Endpoint (SUR): Serum creatinine
Study 9316182 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8487647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8487647 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8487647 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 8487647 — Surrogate Endpoint (SUR): Serum testosterone
Study 2681882 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 19826135 — Safety Biomarker (SAF): Reactive oxygen species
Study 8355460 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8355460 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8355460 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8355460 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17555526 — Surrogate Endpoint (SUR): Serum testosterone
Study 6167116 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29890048 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24198300 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24198300 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24198300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19395585 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 9536925 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2469243 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28685560 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 23815742 — Surrogate Endpoint (SUR): Blood pressure
Study 21528596 — Surrogate Endpoint (SUR): Bone mineral density
Study 19210013 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 19210013 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 16845799 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 9815589 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 30633331 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 30633331 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 26011677 — Surrogate Endpoint (SUR): Serum potassium
Study 10460069 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30696533 — Safety Biomarker (SAF): Hyaluronic acid
Study 25091379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25091379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9610786 — Predictive Biomarker (PRD): GGN mRNA
Genes: GGN
Study 9610786 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31286736 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31286736 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 15565481 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8582541 — Surrogate Endpoint (SUR): Blood pressure
Study 30096704 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 19913325 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16118293 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16118293 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17594775 — Surrogate Endpoint (SUR): Bone mineral density
Study 7697252 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 21418799 — Surrogate Endpoint (SUR): Blood pressure
Study 18222258 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 3885850 — Surrogate Endpoint (SUR): Serum creatinine
Study 31721447 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27552990 — Predictive Biomarker (PRD): DOCK3 mRNA
Genes: DOCK3; KIAA0299; MOCA
Study 21090334 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21090334 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21090334 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14719195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30569662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28650204 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 25905795 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 23943734 — Surrogate Endpoint (SUR): Blood pressure
Study 21257977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27843047 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19852289 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19852289 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24092940 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17661847 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17661847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2125252 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2125252 — Surrogate Endpoint (SUR): Serum creatinine
Study 19631773 — Predictive Biomarker (PRD): RUNX2 mRNA
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 7707108 — Predictive Biomarker (PRD): Hormone receptor
Study 19609048 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19609048 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8574256 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8574256 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 8574256 — Surrogate Endpoint (SUR): Blood pressure
Study 30027768 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20386309 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12675869 — Surrogate Endpoint (SUR): Blood pressure
Study 1827418 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9719037 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 3190800 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26386786 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 1310497 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 17344588 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17344588 — Surrogate Endpoint (SUR): Serum creatinine
Study 17344588 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7884791 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7884791 — Surrogate Endpoint (SUR): Blood pressure
Study 28260202 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21596605 — Surrogate Endpoint (SUR): Blood pressure
Study 18000659 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18000659 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 17010056 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9094871 — Surrogate Endpoint (SUR): Blood pressure
Study 9094871 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29490310 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24472084 — Surrogate Endpoint (SUR): Serum uric acid
Study 17907112 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28887690 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 28887690 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 21456017 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30694011 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29044764 — Surrogate Endpoint (SUR): Blood pressure
Study 25116230 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19761536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15990127 — Surrogate Endpoint (SUR): Blood pressure
Study 7821124 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26476943 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23775260 — Surrogate Endpoint (SUR): Blood pressure
Study 22841432 — Surrogate Endpoint (SUR): Blood pressure
Study 8684686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 1904892 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 29171848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29171848 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16636540 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12559795 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8987040 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8427660 — Surrogate Endpoint (SUR): Blood pressure
Study 30665819 — Surrogate Endpoint (SUR): Bone mineral density
Study 24856575 — Surrogate Endpoint (SUR): Blood pressure
Study 21199306 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 11854123 — Surrogate Endpoint (SUR): Blood pressure
Study 11898768 — Safety Biomarker (SAF): Reactive oxygen species
Study 10211862 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10211862 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 10211862 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 27273879 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study 7892259 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 7892259 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31469710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27584910 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53