TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00961701 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00434486 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study NCT03922685 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03244943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00317252 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02327416 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01460381 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04074551 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01743014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02019394 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT03081234 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03081234 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02442674 — Surrogate Endpoint (SUR): Serum sodium
Study NCT04108013 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01983917 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00085423 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02735850 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00004816 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03901261 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study NCT02747862 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT01246011 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study NCT03903926 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03359694 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02608151 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT04920435 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT04400994 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01824017 — Predictive Biomarker (PRD): RALBP1 mRNA
Genes: RALBP1; RLIP; RLIP1; RLIP76
Study NCT02153918 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT00128063 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01950234 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01140854 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01551641 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03201250 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00896909 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01889212 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01889212 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03168945 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02406820 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03424135 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03578042 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03978624 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT02723110 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study NCT04674618 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT00802971 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT05244395 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04273490 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study NCT04273490 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04273490 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02524938 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT02524938 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01774526 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01774526 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01774526 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01774526 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01774526 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01737801 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03972267 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT02493959 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT04284904 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT04284904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01908816 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02717897 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT03449836 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT00523211 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02394834 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02394834 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT02751099 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02434432 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00288834 — Predictive Biomarker (PRD): SEMG1 mRNA
Genes: SEMG1; SEMG
Study NCT05617105 — Predictive Biomarker (PRD): TFE3 mRNA
Genes: TFE3; BHLHE33
Study NCT01475058 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03311906 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03724526 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04642937 — Predictive Biomarker (PRD): CD200 mRNA
Genes: CD200; MOX1; MOX2; My033
Study NCT02737332 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00337883 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04152499 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04152499 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04152499 — Predictive Biomarker (PRD): TACSTD2 mRNA
Genes: TACSTD2; GA733-1; M1S1; TROP2
Study NCT05645991 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04675853 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00003875 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03860155 — Predictive Biomarker (PRD): ABCB5 mRNA
Genes: ABCB5
Study NCT00076804 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02716935 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT01097941 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00540293 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02944383 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02944383 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT02208674 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00804713 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT00804713 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02915965 — Predictive Biomarker (PRD): DCX mRNA
Genes: DCX; DBCN; LISX
Study NCT03173144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01356836 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study NCT01356836 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT02075827 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02889978 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02443259 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT02038907 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT00348088 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study NCT01142479 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00195234 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03915730 — Predictive Biomarker (PRD): PGLYRP
Genes: PGLYRP1; TAG7; PGRP; PGRP-S; PGRPS
Study NCT02643277 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00698893 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT03310567 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT00302718 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04477772 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study NCT03758404 — Predictive Biomarker (PRD): CNGA3 mRNA
Genes: CNGA3; CNCG3
Study NCT04819399 — Predictive Biomarker (PRD): EPCAM mRNA
Genes: EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Study NCT00399256 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT00399256 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT05476120 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03320044 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04243278 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04347226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00915928 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01094288 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT02291770 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01574963 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT01574963 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT01574963 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02454660 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00010192 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00675753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00675753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01983709 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03293784 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01219413 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01007942 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03844958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02687672 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04384744 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study NCT00398996 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01965470 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02636192 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT01760525 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01760525 — Predictive Biomarker (PRD): MDM2
Genes: HDM2; MGC5370
Study NCT01709838 — Predictive Biomarker (PRD): Liver iron
Study NCT01164345 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02322736 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02322736 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT02601066 — Predictive Biomarker (PRD): LMNA mRNA
Genes: LMNA; LMN1
Study NCT00894738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02145312 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01925638 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00805753 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01592669 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01206049 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03097224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00487084 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT02822404 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT01753466 — Surrogate Endpoint (SUR): Serum sodium
Study NCT04243434 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT01935466 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT01258374 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT03011736 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT00681200 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02345824 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02345824 — Predictive Biomarker (PRD): CDK6 mRNA
Genes: CDK6; CDKN6
Study NCT04428333 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01271751 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT01271751 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT01271751 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02279537 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02279537 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03775720 — Predictive Biomarker (PRD): SLC4A5 mRNA
Genes: SLC4A5; NBC4
Study NCT04193306 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04193306 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00134693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04366427 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02143635 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT05619562 — Predictive Biomarker (PRD): EPCAM mRNA
Genes: EPCAM; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Study NCT03001310 — Predictive Biomarker (PRD): CNGB3 mRNA
Genes: CNGB3
Study NCT03310411 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00548093 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00548093 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00986063 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT00300625 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03888950 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00813527 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00813527 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00397059 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01612299 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT01494935 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03192072 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04356417 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00309894 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02456896 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02456896 — Safety Biomarker (SAF): BDNF
Study NCT03525925 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00139685 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02578264 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02767531 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT00314223 — Predictive Biomarker (PRD): HCN1 mRNA
Genes: HCN1; BCNG1
Study NCT00314223 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study NCT00314223 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study NCT02851329 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01700036 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT03802955 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT02035124 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00001918 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01020344 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03805581 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01948388 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT04059224 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT01953328 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03810755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03046407 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT00148824 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03205891 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT02175316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00237783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01938963 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02114554 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT00517179 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00621452 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02378350 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03884452 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT04413864 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02424695 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study NCT02424695 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02770677 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00075075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02768987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02768987 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT06137690 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT02082821 — Predictive Biomarker (PRD): P2RX1 mRNA
Genes: P2RX1; P2X1
Study NCT00244530 — Safety Biomarker (SAF): 51Cr-EDTA
Study NCT02302547 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00150943 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02951442 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01440036 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study NCT02939833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00539747 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03677895 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01278719 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03253211 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02696798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00565864 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT03512860 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study NCT03512860 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT03579888 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03329651 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT00118508 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04376606 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01267994 — Safety Biomarker (SAF): Interleukin 1
Study NCT00191971 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT00632541 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02170714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00384631 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00384631 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05174494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02276014 — Predictive Biomarker (PRD): BCO1 mRNA
Genes: BCO1; BCDO; BCDO1; BCMO1
Study NCT00617318 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02008786 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01879267 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study NCT01789827 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00257218 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04242849 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT04242849 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT00314145 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01794468 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study NCT04140110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00081692 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00171314 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01205451 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02713672 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02713672 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19