TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29127510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21312072 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 21312072 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 20383871 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 2171792 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 21870979 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20584997 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6127896 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31092165 — Surrogate Endpoint (SUR): Blood pressure
Study 28727908 — Predictive Biomarker (PRD): FFAR1 mRNA
Genes: FFAR1; GPR40
Study 23566419 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23566419 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 19549430 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 19549430 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19549430 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10748306 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8729585 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8729585 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24253810 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22120090 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22120090 — Surrogate Endpoint (SUR): Serum sodium
Study 22120090 — Surrogate Endpoint (SUR): Serum potassium
Study 9333181 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7631088 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 18279058 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16780768 — Surrogate Endpoint (SUR): Blood pressure
Study 20815182 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 19083445 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12785023 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10716475 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10716475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10716475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10716475 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10716475 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 24514907 — Safety Biomarker (SAF): Cytochrome c
Study 24514907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20808314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11815322 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 24906976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24906976 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 17891043 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16866809 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27094801 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18990766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12859466 — Surrogate Endpoint (SUR): Blood pressure
Study 26629812 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 21401662 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 8839728 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31206358 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 26780033 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 24931900 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 24931900 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17921900 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 400246 — Surrogate Endpoint (SUR): Blood pressure
Study 26158794 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 20202636 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 20202636 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 20202636 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 17921409 — Surrogate Endpoint (SUR): Bone mineral density
Study 12232562 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24119605 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17602935 — Surrogate Endpoint (SUR): Blood pressure
Study 9926153 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31729990 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25391326 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 23105144 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21320217 — Surrogate Endpoint (SUR): Blood pressure
Study 12804346 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8888809 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 6210278 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 11521914 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 7978412 — Surrogate Endpoint (SUR): Blood pressure
Study 9954 — Surrogate Endpoint (SUR): Blood pressure
Study 23055051 — Predictive Biomarker (PRD): SLC9A1 mRNA
Genes: SLC9A1; APNH1; NHE1
Study 23055051 — Predictive Biomarker (PRD): TLX2 mRNA
Genes: TLX2; HOX11L1; NCX
Study 23055051 — Safety Biomarker (SAF): Cytochrome c
Study 10616841 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 9156268 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 9156268 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 9156268 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 30241504 — Surrogate Endpoint (SUR): Blood pressure
Study 30241504 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30241504 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 15915352 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24219860 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 24219860 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 22808810 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 16786236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16786236 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12539556 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 9397242 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9397242 — Surrogate Endpoint (SUR): Blood pressure
Study 2822298 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29557858 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 18200024 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 15994288 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 8558209 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25673979 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 25673979 — Safety Biomarker (SAF): Hyaluronic acid
Study 20052352 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20052352 — Surrogate Endpoint (SUR): Bone mineral density
Study 17610534 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12366619 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12366619 — Surrogate Endpoint (SUR): Blood pressure
Study 12366619 — Surrogate Endpoint (SUR): Serum creatinine
Study 12366619 — Surrogate Endpoint (SUR): Serum potassium
Study 7576743 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19166694 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15057738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21992747 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21992747 — Predictive Biomarker (PRD): IDE mRNA
Genes: IDE
Study 21992747 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 12551742 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 28718073 — Surrogate Endpoint (SUR): Urinary oxalate
Study 24152824 — Predictive Biomarker (PRD): miR-106b
Genes: MIR106B
Study 7979855 — Surrogate Endpoint (SUR): Bone mineral density
Study 25782227 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 29877199 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9159561 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3655310 — Monitoring Biomarker (MOI): HBV DNA
Study 11903319 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21611728 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16351767 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 29151102 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 29151102 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 29151102 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 25272194 — Surrogate Endpoint (SUR): Blood pressure
Study 19471949 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 19471949 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 19471949 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 19471949 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 10550446 — Surrogate Endpoint (SUR): Bone mineral density
Study 10550446 — Surrogate Endpoint (SUR): Serum calcium
Study 21929736 — Surrogate Endpoint (SUR): Blood pressure
Study 9778325 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 28328159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25754254 — Surrogate Endpoint (SUR): Blood pressure
Study 24402015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9323940 — Surrogate Endpoint (SUR): Blood pressure
Study 7954035 — Surrogate Endpoint (SUR): Blood pressure
Study 26855568 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 16286173 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 26917577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9469362 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7630200 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 20980201 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20980201 — Surrogate Endpoint (SUR): Blood pressure
Study 17464690 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 30677465 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11561769 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30630803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30630803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26614548 — Surrogate Endpoint (SUR): Pathological complete response
Study 25348723 — Surrogate Endpoint (SUR): Blood pressure
Study 25885506 — Surrogate Endpoint (SUR): Serum creatinine
Study 25885506 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16248471 — Surrogate Endpoint (SUR): Blood pressure
Study 10097253 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 10097253 — Surrogate Endpoint (SUR): Serum calcium
Study 17457187 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 11361053 — Surrogate Endpoint (SUR): Blood pressure
Study 31051499 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 31051499 — Predictive Biomarker (PRD): WRAP53 mRNA
Genes: WRAP53; TCAB1; WDR79
Study 27488933 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 27488933 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19808911 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 304478 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 27176449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27176449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12054164 — Surrogate Endpoint (SUR): Bone mineral density
Study 7767551 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2181102 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19476631 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15677729 — Predictive Biomarker (PRD): AMPD1 mRNA
Genes: AMPD1
Study 7613098 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7613098 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 2620952 — Surrogate Endpoint (SUR): Blood pressure
Study 15562040 — Surrogate Endpoint (SUR): Serum creatinine
Study 12092185 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7942489 — Surrogate Endpoint (SUR): Blood pressure
Study 28628402 — Surrogate Endpoint (SUR): Serum calcium
Study 28628402 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 24273887 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18971536 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18971536 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 18971536 — Surrogate Endpoint (SUR): Blood pressure
Study 10739171 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 2951198 — Surrogate Endpoint (SUR): Blood pressure
Study 26991772 — Surrogate Endpoint (SUR): Blood pressure
Study 1511712 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 1511712 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31383985 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22008919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22008919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22008919 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22008919 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22008919 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 22410289 — Surrogate Endpoint (SUR): Blood pressure
Study 19508973 — Surrogate Endpoint (SUR): Serum creatinine
Study 19508973 — Surrogate Endpoint (SUR): Blood pressure
Study 30170304 — Surrogate Endpoint (SUR): Blood pressure
Study 30170304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12140349 — Surrogate Endpoint (SUR): Blood pressure
Study 7589767 — Surrogate Endpoint (SUR): Blood pressure
Study 22838386 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17439512 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 30653423 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30429461 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 11874925 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 2139523 — Predictive Biomarker (PRD): Hormone receptor
Study 22300528 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 22300528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22300528 — Safety Biomarker (SAF): BDNF
Study 22300528 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19918047 — Surrogate Endpoint (SUR): Bone mineral density
Study 16959916 — Safety Biomarker (SAF): Reactive oxygen species
Study 2691174 — Surrogate Endpoint (SUR): Blood pressure
Study 29245361 — Surrogate Endpoint (SUR): Blood pressure
Study 17129461 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30557693 — Predictive Biomarker (PRD): ALAD mRNA
Genes: ALAD
Study 21749907 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21749907 — Safety Biomarker (SAF): BDNF
Study 15249503 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 3071588 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3071588 — Surrogate Endpoint (SUR): Blood pressure
Study 16861404 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 15309453 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9251504 — Surrogate Endpoint (SUR): Blood pressure
Study 9251504 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30928954 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 16269957 — Surrogate Endpoint (SUR): Blood pressure
Study 7026094 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 28893415 — Safety Biomarker (SAF): Derived neutrophil to lymphocyte
Study 28893415 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 26166613 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 7621842 — Surrogate Endpoint (SUR): Blood pressure
Study 15595587 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19046094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19046094 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 19046094 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26181707 — Surrogate Endpoint (SUR): Serum creatinine
Study 24143917 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 24628789 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22459310 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12383572 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10420746 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6716222 — Surrogate Endpoint (SUR): Serum calcium
Study 24498853 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16236737 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8845088 — Surrogate Endpoint (SUR): Blood pressure
Study 8845088 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30856 — Surrogate Endpoint (SUR): Blood pressure
Study 25466493 — Surrogate Endpoint (SUR): Blood pressure
Study 21117970 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21117970 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21117970 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21117970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16717336 — Surrogate Endpoint (SUR): Blood pressure
Study 15549367 — Surrogate Endpoint (SUR): Blood pressure
Study 8483989 — Surrogate Endpoint (SUR): Blood pressure
Study 20433766 — Surrogate Endpoint (SUR): Blood pressure
Study 12904324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10370739 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6836710 — Surrogate Endpoint (SUR): Blood pressure
Study 25088287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25088287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19589793 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28003500 — Surrogate Endpoint (SUR): Blood pressure
Study 28003500 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9663912 — Surrogate Endpoint (SUR): Blood pressure
Study 16303008 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 20849805 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17522594 — Surrogate Endpoint (SUR): Blood pressure
Study 14693058 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14693058 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 14693058 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9345020 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 9345020 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24351534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15665711 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 1345040 — Surrogate Endpoint (SUR): Blood pressure
Study 26354567 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23602068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18416473 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18416473 — Surrogate Endpoint (SUR): Blood pressure
Study 18416473 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12884990 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26365555 — Surrogate Endpoint (SUR): Blood pressure
Study 15673386 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study 30422911 — Surrogate Endpoint (SUR): Bone mineral density
Study 25375400 — Safety Biomarker (SAF): Hyaluronic acid
Study 22516910 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 30630500 — Predictive Biomarker (PRD): EHF mRNA
Genes: EHF; ESE3; ESE3B; ESEJ