TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18997196 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10202985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10202985 — Safety Biomarker (SAF): Interleukin 1
Study 7595908 — Surrogate Endpoint (SUR): Blood pressure
Study 28803124 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 23437966 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 21752726 — Surrogate Endpoint (SUR): Blood pressure
Study 12798881 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1475511 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 6383615 — Surrogate Endpoint (SUR): Blood pressure
Study 6383615 — Surrogate Endpoint (SUR): Serum sodium
Study 27491226 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18574391 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18574391 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 18574391 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 18574391 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 20453626 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 20453626 — Surrogate Endpoint (SUR): Bone mineral density
Study 29262841 — Surrogate Endpoint (SUR): Blood pressure
Study 26427627 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 8989740 — Surrogate Endpoint (SUR): Blood pressure
Study 26733011 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 17429836 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 17429836 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 16338283 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12380231 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28449368 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21225090 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21225090 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8844442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1321198 — Surrogate Endpoint (SUR): Blood pressure
Study 23661492 — Surrogate Endpoint (SUR): Bone mineral density
Study 24423369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 14632678 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9197949 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 15889392 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 11938860 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 3426824 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25257752 — Surrogate Endpoint (SUR): Blood pressure
Study 25346595 — Surrogate Endpoint (SUR): Blood pressure
Study 15087294 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 15087294 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15087294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15087294 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9309457 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20164363 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 20164363 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 18682511 — Surrogate Endpoint (SUR): Bone mineral density
Study 27722092 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12766967 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10631440 — Surrogate Endpoint (SUR): Blood pressure
Study 2256719 — Predictive Biomarker (PRD): Hormone receptor
Study 25284266 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15673408 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 26073353 — Surrogate Endpoint (SUR): Blood pressure
Study 22089106 — Surrogate Endpoint (SUR): Blood pressure
Study 9010697 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18502300 — Surrogate Endpoint (SUR): Blood pressure
Study 12972476 — Surrogate Endpoint (SUR): Bone mineral density
Study 31660706 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 31660706 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 31660706 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 27571889 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 23312069 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23312069 — Safety Biomarker (SAF): BDNF
Study 15286547 — Surrogate Endpoint (SUR): Blood pressure
Study 29543566 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29543566 — Predictive Biomarker (PRD): Hormone receptor
Study 15585311 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15585311 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 8689881 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30866943 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25577869 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 25577869 — Surrogate Endpoint (SUR): Blood pressure
Study 25577869 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21295843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 17686164 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 3428346 — Surrogate Endpoint (SUR): Serum potassium
Study 8860097 — Surrogate Endpoint (SUR): Blood pressure
Study 1512524 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 1512524 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TBX2 mRNA
Genes: TBX2
Study 30803503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30803503 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25823387 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 10648311 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8712329 — Surrogate Endpoint (SUR): Blood pressure
Study 29300100 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 29300100 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 24169242 — Surrogate Endpoint (SUR): Blood pressure
Study 21915866 — Monitoring Biomarker (MOI): HBV DNA
Study 18249219 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 18249219 — Predictive Biomarker (PRD): ADRB3 mRNA
Genes: ADRB3; ADRB3R; B3AR
Study 18249219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18249219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18249219 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 18249219 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 18249219 — Predictive Biomarker (PRD): LEPROT mRNA
Genes: LEPROT; LEPR; OBR
Study 11128360 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11128360 — Surrogate Endpoint (SUR): Blood pressure
Study 31146772 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 31146772 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 28032641 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26444022 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 23660094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23660094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23660094 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23660094 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17350370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21725053 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 21725053 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 12638099 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 23503652 — Predictive Biomarker (PRD): E2F3 mRNA
Genes: E2F3; KIAA0075
Study 23503652 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-125b
Study 20600025 — Monitoring Biomarker (MOI): HBV DNA
Study 8874257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15310639 — Surrogate Endpoint (SUR): Blood pressure
Study 11781224 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28911141 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 23638898 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21195942 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30530462 — Surrogate Endpoint (SUR): Blood pressure
Study 17336254 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 8726096 — Surrogate Endpoint (SUR): Blood pressure
Study 6795915 — Surrogate Endpoint (SUR): Blood pressure
Study 28045958 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17358099 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9809620 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20561878 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19231245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2728827 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24672937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15959616 — Surrogate Endpoint (SUR): Bone mineral density
Study 214866 — Surrogate Endpoint (SUR): Blood pressure
Study 22703536 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 26039911 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26039911 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 26039911 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19065655 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 19065655 — Safety Biomarker (SAF): DRD2
Study 23221984 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23221984 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19712983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17848804 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 17848804 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 17848804 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 17848804 — Safety Biomarker (SAF): Th2 cell
Study 6794075 — Surrogate Endpoint (SUR): Blood pressure
Study 29030692 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15990669 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 15990669 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 21540202 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study 14729239 — Surrogate Endpoint (SUR): Blood pressure
Study 2649864 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17873305 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11518846 — Surrogate Endpoint (SUR): Blood pressure
Study 22134388 — Surrogate Endpoint (SUR): Blood pressure
Study 30206618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27690741 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27690741 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 14668709 — Surrogate Endpoint (SUR): Serum creatinine
Study 6308996 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6308996 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30454724 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30615489 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30615489 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21733988 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21733988 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 17089153 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 12215207 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12215207 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 10786501 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 27480383 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 23926586 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 23926586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 21068351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26321469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26321469 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 25168637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21029014 — Surrogate Endpoint (SUR): Blood pressure
Study 10619581 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10619581 — Surrogate Endpoint (SUR): Blood pressure
Study 31125701 — Surrogate Endpoint (SUR): Blood pressure
Study 25546556 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11516602 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31003735 — Predictive Biomarker (PRD): PPP3CA mRNA
Genes: PPP3CA; CALNA; CNA
Study 9346997 — Surrogate Endpoint (SUR): Serum sodium
Study 3098950 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 30345850 — Surrogate Endpoint (SUR): Blood pressure
Study 24050764 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24050764 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18083065 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 2045530 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2045530 — Surrogate Endpoint (SUR): Blood pressure
Study 24907403 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 9192239 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26231133 — Surrogate Endpoint (SUR): Blood pressure
Study 8878342 — Safety Biomarker (SAF): DRD2
Study 1447078 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1447078 — Surrogate Endpoint (SUR): Serum sodium
Study 24038028 — Predictive Biomarker (PRD): APAF1 mRNA
Genes: APAF1; KIAA0413
Study 24038028 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 24038028 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 24038028 — Predictive Biomarker (PRD): Induced myeloid leukemia cell differentiation protein Mcl-1
Genes: MCL1; BCL2L3
Study 24038028 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study 24038028 — Predictive Biomarker (PRD): BCL2L1 mRNA
Genes: BCL2L1; BCL2L; BCLX
Study 24038028 — Predictive Biomarker (PRD): ENDOG mRNA
Genes: ENDOG
Study 24038028 — Predictive Biomarker (PRD): YWHAB mRNA
Genes: YWHAB
Study 24038028 — Predictive Biomarker (PRD): YWHAQ mRNA
Genes: YWHAQ
Study 20028946 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1330434 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 25262260 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10980827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7669490 — Surrogate Endpoint (SUR): Blood pressure
Study 7026073 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19278844 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19278844 — Surrogate Endpoint (SUR): Blood pressure
Study 31092142 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 26374448 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 22269592 — Surrogate Endpoint (SUR): Blood pressure
Study 10690132 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21704242 — Predictive Biomarker (PRD): SLC38A3 mRNA
Genes: SLC38A3; G17; NAT1; SN1; SNAT3
Study 21704242 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 21704242 — Surrogate Endpoint (SUR): Blood pressure
Study 19428083 — Safety Biomarker (SAF): Reactive oxygen species
Study 19428083 — Surrogate Endpoint (SUR): Sperm parameters
Study 15948098 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12841537 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 2693691 — Safety Biomarker (SAF): Hyaluronic acid
Study 12426514 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 12426514 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12426514 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30471795 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 30471795 — Predictive Biomarker (PRD): TLR6 mRNA
Genes: TLR6
Study 30471795 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 30471795 — Safety Biomarker (SAF): Interleukin 1
Study 11096166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31726485 — Surrogate Endpoint (SUR): Blood pressure
Study 28137609 — Surrogate Endpoint (SUR): Blood pressure
Study 28137609 — Surrogate Endpoint (SUR): Serum potassium
Study 8336864 — Surrogate Endpoint (SUR): Bone mineral density
Study 3528119 — Surrogate Endpoint (SUR): Blood pressure
Study 21050796 — Surrogate Endpoint (SUR): Bone mineral density
Study 16596114 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 16596114 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16596114 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 12575402 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study 29119483 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 24600214 — Surrogate Endpoint (SUR): Blood pressure
Study 20435291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20435291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20435291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11046211 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11046211 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3024826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 30913065 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 28391875 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28391875 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28391875 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19111610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15259281 — Surrogate Endpoint (SUR): Bone mineral density
Study 31872213 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31872213 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25601933 — Surrogate Endpoint (SUR): Blood pressure
Study 16287453 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16287453 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 16287453 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29902061 — Surrogate Endpoint (SUR): Blood pressure
Study 23924446 — Predictive Biomarker (PRD): GLI2 mRNA
Genes: GLI2; THP
Study 29532734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29532734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29436152 — Surrogate Endpoint (SUR): Blood pressure
Study 22773291 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 19965548 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 8675360 — Surrogate Endpoint (SUR): Serum creatinine
Study 1677616 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 25008950 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25008950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25008950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25008950 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25008950 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31248843 — Safety Biomarker (SAF): Human leucocyte antigen
Study 24996030 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 24996030 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20473067 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 11874442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11874442 — Surrogate Endpoint (SUR): Blood pressure
Study 2185342 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF