TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25288176 — Surrogate Endpoint (SUR): Blood pressure
Study 28479852 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 28479852 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 1729935 — Surrogate Endpoint (SUR): Blood pressure
Study 29278428 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26991619 — Surrogate Endpoint (SUR): Blood pressure
Study 9681726 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9681726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2572699 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 23057058 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8115195 — Surrogate Endpoint (SUR): Blood pressure
Study 793706 — Surrogate Endpoint (SUR): Serum creatinine
Study 793706 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28923573 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28923573 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28923573 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 21784378 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21784378 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15487693 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study 10024902 — Surrogate Endpoint (SUR): Bone mineral density
Study 10024902 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8002124 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30498758 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 16046716 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 16046716 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24362488 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20197194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11857045 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 7564082 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22091554 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19284108 — Surrogate Endpoint (SUR): Blood pressure
Study 2879733 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28335697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28335697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27339453 — Surrogate Endpoint (SUR): Blood pressure
Study 16276166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16276166 — Safety Biomarker (SAF): Interleukin 1
Study 16276166 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23131078 — Surrogate Endpoint (SUR): Serum creatinine
Study 10622346 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 29890569 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22682022 — Surrogate Endpoint (SUR): Serum creatinine
Study 15894592 — Surrogate Endpoint (SUR): Blood pressure
Study 30633202 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18554182 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10617008 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 19017751 — Predictive Biomarker (PRD): ENPP1 mRNA
Genes: ENPP1; M6S1; NPPS; PC1; PDNP1
Study 11266197 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11266197 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11266197 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7987882 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2547465 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26496720 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 23680766 — Surrogate Endpoint (SUR): Blood pressure
Study 11028740 — Surrogate Endpoint (SUR): Blood pressure
Study 16464637 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16464637 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 14500473 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 10710869 — Surrogate Endpoint (SUR): Bone mineral density
Study 8992904 — Surrogate Endpoint (SUR): Serum creatinine
Study 30530284 — Surrogate Endpoint (SUR): Blood pressure
Study 19840063 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19840063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15361517 — Surrogate Endpoint (SUR): Blood pressure
Study 6141317 — Surrogate Endpoint (SUR): Blood pressure
Study 22864525 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 6848299 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 27649854 — Safety Biomarker (SAF): miR-30c
Study 27649854 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 23161305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18780501 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 19859781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19859781 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19859781 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12414852 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8961992 — Surrogate Endpoint (SUR): Serum creatinine
Study 1742507 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 31931762 — Surrogate Endpoint (SUR): Blood pressure
Study 19757215 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8822535 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 1532613 — Surrogate Endpoint (SUR): Blood pressure
Study 22960288 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 20456282 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17265078 — Predictive Biomarker (PRD): SLC6A1 mRNA
Genes: SLC6A1; GABATR; GABT1; GAT1
Study 24267043 — Surrogate Endpoint (SUR): Blood pressure
Study 24267043 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22384541 — Predictive Biomarker (PRD): ACTA1 mRNA
Genes: ACTA1; ACTA
Study 11403751 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26968165 — Surrogate Endpoint (SUR): Bone mineral density
Study 28362562 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 28362562 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 16736432 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 16736432 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 16736432 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10082852 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 10082852 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 10082852 — Safety Biomarker (SAF): BDNF
Study 23019939 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7005474 — Surrogate Endpoint (SUR): Blood pressure
Study 27885763 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 21437363 — Surrogate Endpoint (SUR): Blood pressure
Study 18035430 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30597578 — Predictive Biomarker (PRD): PER2 mRNA
Genes: PER2; KIAA0347
Study 30597578 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 27079717 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 22990330 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16967682 — Surrogate Endpoint (SUR): Serum calcium
Study 3057674 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24354929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24354929 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24354929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22733462 — Surrogate Endpoint (SUR): Blood pressure
Study 22733462 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 26062916 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 23588439 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20378504 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20378504 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17037284 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17037284 — Surrogate Endpoint (SUR): Blood pressure
Study 7575771 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7870911 — Surrogate Endpoint (SUR): Blood pressure
Study 24474396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28077588 — Predictive Biomarker (PRD): SLA mRNA
Genes: SLA; SLAP; SLAP1
Study 24241092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24241092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19846849 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19846849 — Surrogate Endpoint (SUR): Blood pressure
Study 17584910 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 9580247 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 9580247 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 9580247 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20530505 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 16608040 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16608040 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30452713 — Predictive Biomarker (PRD): RNASE2 mRNA
Genes: RNASE2; EDN; RNS2
Study 26868849 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 26868849 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 15836710 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10480285 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 8728306 — Surrogate Endpoint (SUR): Blood pressure
Study 24463448 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 17646219 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15142875 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 11161543 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 27919627 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23475636 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16476851 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 15379272 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8992351 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31978565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24998617 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24998617 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 24998617 — Surrogate Endpoint (SUR): Blood pressure
Study 23163616 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 23163616 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 11390253 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27393499 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27393499 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27393499 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27393499 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 27393499 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 9568663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9568663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9568663 — Surrogate Endpoint (SUR): Bacterial count
Study 16864931 — Surrogate Endpoint (SUR): Blood pressure
Study 9335081 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9335081 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22854050 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22854050 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 1281046 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 29489681 — Surrogate Endpoint (SUR): Blood pressure
Study 20175053 — Surrogate Endpoint (SUR): Serum creatinine
Study 9485250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9485250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9485250 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28347975 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 30473185 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 28295686 — Predictive Biomarker (PRD): FAU mRNA
Genes: FAU
Study 27240787 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17064200 — Surrogate Endpoint (SUR): Blood pressure
Study 9327820 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 23189232 — Surrogate Endpoint (SUR): Blood pressure
Study 25002389 — Surrogate Endpoint (SUR): Blood pressure
Study 20568303 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18502512 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 10081520 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2309606 — Surrogate Endpoint (SUR): Blood pressure
Study 25755212 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 25755212 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9762797 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27545871 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 20049753 — Monitoring Biomarker (MOI): HBV DNA
Study 9822445 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9822445 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9822445 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2661843 — Surrogate Endpoint (SUR): Serum sodium
Study 20605427 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19424052 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 1572248 — Surrogate Endpoint (SUR): Blood pressure
Study 27645694 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 1766577 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 25197738 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 9734472 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 9734472 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1894852 — Surrogate Endpoint (SUR): Blood pressure
Study 31996108 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 31996108 — Surrogate Endpoint (SUR): Blood pressure
Study 31996108 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14605050 — Surrogate Endpoint (SUR): Serum creatinine
Study 15908660 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21421014 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29705466 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 29705466 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 7569093 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 7569093 — Surrogate Endpoint (SUR): Blood pressure
Study 352097 — Surrogate Endpoint (SUR): Serum creatinine
Study 26271132 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 15257956 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11565838 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11565838 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11565838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10169297 — Surrogate Endpoint (SUR): Blood pressure
Study 10989958 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20571299 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 30580680 — Surrogate Endpoint (SUR): Blood pressure
Study 21444807 — Predictive Biomarker (PRD): CNTF mRNA
Genes: CNTF
Study 19802659 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9014956 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3553496 — Surrogate Endpoint (SUR): Blood pressure
Study 22142346 — Surrogate Endpoint (SUR): Blood pressure
Study 24101169 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 20386332 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17327864 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14653832 — Surrogate Endpoint (SUR): Bone mineral density
Study 6150320 — Surrogate Endpoint (SUR): Serum creatinine
Study 24736197 — Surrogate Endpoint (SUR): Bone mineral density
Study 22810435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20938172 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 15745927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8382712 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30293597 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 30293597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30293597 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30293597 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 27528547 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 24743579 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24743579 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17023874 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15863490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19939445 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9397059 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25056277 — Surrogate Endpoint (SUR): Blood pressure
Study 22059803 — Surrogate Endpoint (SUR): Blood pressure
Study 11533291 — Surrogate Endpoint (SUR): Bone mineral density
Study 30170305 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 21752292 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 21752292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 8810610 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31857506 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31857506 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21843929 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 21843929 — Predictive Biomarker (PRD): NOS3 mRNA
Genes: NOS3
Study 17438403 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17438403 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22409923 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20820124 — Surrogate Endpoint (SUR): Blood pressure
Study 14640996 — Surrogate Endpoint (SUR): Blood pressure
Study 15545509 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 7814228 — Surrogate Endpoint (SUR): Probing pocket depth
Study 791332 — Surrogate Endpoint (SUR): Blood pressure
Study 28921414 — Surrogate Endpoint (SUR): Blood pressure
Study 21947289 — Surrogate Endpoint (SUR): Blood pressure
Study 27436224 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27436224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20951370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12410536 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12410536 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7617555 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28079572 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 29729189 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24496202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24496202 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 24496202 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24496202 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 24496202 — Safety Biomarker (SAF): IL-6 and IL-10