TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19930866 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19930866 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16825591 — Predictive Biomarker (PRD): PDE4D mRNA
Genes: PDE4D; DPDE3
Study 26650153 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23908086 — Surrogate Endpoint (SUR): Blood pressure
Study 23908086 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23908086 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23908086 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21890003 — Predictive Biomarker (PRD): SULT1A3 mRNA
Genes: SULT1A3; STM
Study 9237640 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 25434315 — Monitoring Biomarker (MOI): HBV DNA
Study 18619828 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18619828 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9148226 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16122909 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 29981250 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25577762 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21257003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21257003 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21257003 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19415804 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 23340588 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20931221 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9404747 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3422105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28053714 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 24078975 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12810502 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 8672321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8672321 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27787547 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 12898792 — Surrogate Endpoint (SUR): Serum testosterone
Study 1746428 — Surrogate Endpoint (SUR): Blood pressure
Study 31772615 — Surrogate Endpoint (SUR): Blood pressure
Study 9822096 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27072928 — Surrogate Endpoint (SUR): Blood pressure
Study 11677363 — Surrogate Endpoint (SUR): Blood pressure
Study 29704456 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 6278914 — Surrogate Endpoint (SUR): Blood pressure
Study 28026727 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 24678939 — Surrogate Endpoint (SUR): Blood pressure
Study 19147138 — Surrogate Endpoint (SUR): Blood pressure
Study 17071945 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 30460598 — Surrogate Endpoint (SUR): Blood pressure
Study 17537217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17537217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17537217 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10928463 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 10928463 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 9483810 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23181634 — Surrogate Endpoint (SUR): Blood pressure
Study 24585444 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 21652619 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 476231 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 29190761 — Surrogate Endpoint (SUR): Blood pressure
Study 23948862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21208928 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9669460 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 18311126 — Surrogate Endpoint (SUR): Blood pressure
Study 6115999 — Surrogate Endpoint (SUR): Serum potassium
Study 23359067 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15533869 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15533869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11287377 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 15718040 — Predictive Biomarker (PRD): SLC1A3 mRNA
Genes: SLC1A3; EAAT1; GLAST; GLAST1
Study 23943468 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16496019 — Surrogate Endpoint (SUR): Blood pressure
Study 31362877 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31362877 — Surrogate Endpoint (SUR): Blood pressure
Study 28558139 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 11877068 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9626635 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23577799 — Surrogate Endpoint (SUR): Blood pressure
Study 7625415 — Surrogate Endpoint (SUR): Blood pressure
Study 29898452 — Surrogate Endpoint (SUR): Blood pressure
Study 23563134 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21070457 — Safety Biomarker (SAF): Hyaluronic acid
Study 16564798 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16564798 — Surrogate Endpoint (SUR): Blood pressure
Study 12548091 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11007152 — Surrogate Endpoint (SUR): Blood pressure
Study 1548570 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26270552 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study 26270552 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 23963138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23963138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17006711 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 17006711 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8650428 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8650428 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25327602 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 14710168 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8435362 — Surrogate Endpoint (SUR): Blood pressure
Study 23364390 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 23364390 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19112496 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 1832291 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29215302 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20156032 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20156032 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20156032 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18587307 — Surrogate Endpoint (SUR): Blood pressure
Study 15687321 — Surrogate Endpoint (SUR): Bone mineral density
Study 8725495 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15607123 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 25641452 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29738412 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 29738412 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 26994987 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25265572 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 31247674 — Surrogate Endpoint (SUR): Blood pressure
Study 21272190 — Surrogate Endpoint (SUR): Blood pressure
Study 19812809 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20309682 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 10822318 — Surrogate Endpoint (SUR): Blood pressure
Study 29138201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2988769 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12830470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7595137 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29701801 — Surrogate Endpoint (SUR): Blood pressure
Study 3276167 — Surrogate Endpoint (SUR): Blood pressure
Study 12364634 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28953776 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28953776 — Safety Biomarker (SAF): BDNF
Study 21247431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21247431 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21247431 — Surrogate Endpoint (SUR): Serum creatinine
Study 19140906 — Surrogate Endpoint (SUR): Blood pressure
Study 9920070 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9920070 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7703390 — Surrogate Endpoint (SUR): Blood pressure
Study 25593284 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 25593284 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21817821 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16886114 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9275110 — Surrogate Endpoint (SUR): Serum creatinine
Study 2646315 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 2646315 — Surrogate Endpoint (SUR): Blood pressure
Study 28609567 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 19949272 — Surrogate Endpoint (SUR): Bone mineral density
Study 17044661 — Surrogate Endpoint (SUR): Blood pressure
Study 11181371 — Predictive Biomarker (PRD): MPG mRNA
Genes: MPG; AAG; ANPG; MID1
Study 8282435 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26281326 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 8704064 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 6748070 — Surrogate Endpoint (SUR): Blood pressure
Study 29750632 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 18034867 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8746602 — Surrogate Endpoint (SUR): Blood pressure
Study 27840301 — Surrogate Endpoint (SUR): Bone mineral density
Study 24691140 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19543672 — Surrogate Endpoint (SUR): Blood pressure
Study 9558774 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 19885850 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 24694667 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 15740629 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 15740629 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22831916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22831916 — Safety Biomarker (SAF): IL-6 and IL-10
Study 1326318 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30058112 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 30058112 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 19864941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19864941 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 19864941 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19864941 — Safety Biomarker (SAF): Interleukin 12
Study 17571741 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15661814 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 15661814 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 15661814 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 15661814 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2148326 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 27866347 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 25562579 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 25562579 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17045352 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17045352 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15325679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2459516 — Surrogate Endpoint (SUR): Blood pressure
Study 21354122 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12967481 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10882962 — Surrogate Endpoint (SUR): Blood pressure
Study 1382623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1382623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 4005083 — Surrogate Endpoint (SUR): Blood pressure
Study 3505604 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 27621026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27621026 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 20924261 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9144368 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29794482 — Surrogate Endpoint (SUR): Blood pressure
Study 16982961 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 16982961 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 16982961 — Surrogate Endpoint (SUR): Blood pressure
Study 15309217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15309217 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 11555394 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11555394 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3060987 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 18306871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18306871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9661597 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2729123 — Surrogate Endpoint (SUR): Blood pressure
Study 18813182 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18813182 — Surrogate Endpoint (SUR): Blood pressure
Study 16543714 — Surrogate Endpoint (SUR): Serum calcium
Study 14526263 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8982557 — Surrogate Endpoint (SUR): Serum creatinine
Study 1468827 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 1468827 — Surrogate Endpoint (SUR): Blood pressure
Study 26557703 — Surrogate Endpoint (SUR): Blood pressure
Study 23053266 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 8129324 — Surrogate Endpoint (SUR): Blood pressure
Study 26215945 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26215945 — Predictive Biomarker (PRD): Hormone receptor
Study 26215945 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 2116817 — Surrogate Endpoint (SUR): Serum calcium
Study 2116817 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 16618293 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27956763 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27956763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15605190 — Surrogate Endpoint (SUR): Bone mineral density
Study 29545413 — Safety Biomarker (SAF): Human leucocyte antigen
Study 30072191 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22146491 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 20637495 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20637495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10673673 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3519766 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3519766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11155088 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9059953 — Surrogate Endpoint (SUR): Bone mineral density
Study 29528986 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18372218 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 27925283 — Safety Biomarker (SAF): DRD2
Study 26156311 — Predictive Biomarker (PRD): TBCA mRNA
Genes: TBCA
Study 19554090 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18093504 — Surrogate Endpoint (SUR): Bone mineral density
Study 11748341 — Surrogate Endpoint (SUR): Bone mineral density
Study 28093041 — Predictive Biomarker (PRD): ISM1 mRNA
Genes: ISM1; C20orf82; ISM
Study 19583077 — Surrogate Endpoint (SUR): Blood pressure
Study 11722052 — Surrogate Endpoint (SUR): Serum creatinine
Study 9142583 — Surrogate Endpoint (SUR): Blood pressure
Study 29360932 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29360932 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28656452 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 24862944 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 19120717 — Surrogate Endpoint (SUR): Blood pressure
Study 14599408 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24336915 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24336915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24336915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24336915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16365072 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 14551359 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14551359 — Surrogate Endpoint (SUR): Blood pressure
Study 18057309 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8464662 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20204340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20204340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20204340 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7546497 — Surrogate Endpoint (SUR): Blood pressure
Study 31111678 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22174431 — Surrogate Endpoint (SUR): Blood pressure
Study 19047289 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 10457212 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10457212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8547546 — Surrogate Endpoint (SUR): Blood pressure
Study 19252142 — Surrogate Endpoint (SUR): Bone mineral density
Study 17106312 — Surrogate Endpoint (SUR): Blood pressure
Study 7197978 — Surrogate Endpoint (SUR): Blood pressure
Study 31418881 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 25618516 — Predictive Biomarker (PRD): FGF5 mRNA
Genes: FGF5
Study 25618516 — Predictive Biomarker (PRD): ATP2B1 mRNA
Genes: ATP2B1; PMCA1
Study 21873796 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 15522140 — Surrogate Endpoint (SUR): Blood pressure
Study 29987109 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 29987109 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29987109 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26778538 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25019209 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 25019209 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 12185609 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9466021 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23864786 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 9614361 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 1920344 — Surrogate Endpoint (SUR): Blood pressure
Study 20634651 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20634651 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16037885 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1