TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15751670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15751670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21124328 — Surrogate Endpoint (SUR): Blood pressure
Study 19455340 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20189754 — Surrogate Endpoint (SUR): Blood pressure
Study 18332472 — Predictive Biomarker (PRD): Hormone receptor
Study 20819525 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17393238 — Predictive Biomarker (PRD): RNASE2 mRNA
Genes: RNASE2; EDN; RNS2
Study 17393238 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15763644 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 7629756 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7629756 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 7629756 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 28708930 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19765430 — Surrogate Endpoint (SUR): Serum creatinine
Study 16751166 — Safety Biomarker (SAF): Hyaluronic acid
Study 8096373 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12723461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11730394 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9213324 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2455105 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2455105 — Surrogate Endpoint (SUR): Blood pressure
Study 29549005 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 29549005 — Surrogate Endpoint (SUR): Blood pressure
Study 28288974 — Surrogate Endpoint (SUR): Blood pressure
Study 23160180 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 23160180 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 16290043 — Safety Biomarker (SAF): Hyaluronic acid
Study 15518675 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 9122733 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25142196 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 7648374 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11319723 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31208472 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 31208472 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31208472 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 31208472 — Predictive Biomarker (PRD): CD70 mRNA
Genes: CD70; CD27L; CD27LG; TNFSF7
Study 18066962 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 15906077 — Surrogate Endpoint (SUR): Blood pressure
Study 12581422 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30819457 — Predictive Biomarker (PRD): EBP mRNA
Genes: EBP
Study 26056021 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 24495633 — Surrogate Endpoint (SUR): Blood pressure
Study 12117084 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 30636632 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 27831502 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20943783 — Surrogate Endpoint (SUR): Serum calcium
Study 20943783 — Surrogate Endpoint (SUR): Bone mineral density
Study 20943783 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 19364963 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11231439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7468987 — Surrogate Endpoint (SUR): Blood pressure
Study 7468987 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26003169 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23218591 — Surrogate Endpoint (SUR): Blood pressure
Study 9248985 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 4207965 — Surrogate Endpoint (SUR): Serum calcium
Study 26561784 — Predictive Biomarker (PRD): OPN1SW mRNA
Genes: OPN1SW; BCP
Study 20884344 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20884344 — Predictive Biomarker (PRD): KLRG1 mRNA
Genes: KLRG1; CLEC15A; MAFA; MAFAL
Study 20884344 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 20884344 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 20884344 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20884344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17582289 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 15364316 — Surrogate Endpoint (SUR): Blood pressure
Study 28279967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21188654 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21188654 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 21188654 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15188805 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7915733 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7915733 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2917701 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2917701 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30142037 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 17498020 — Surrogate Endpoint (SUR): Blood pressure
Study 7978187 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31409915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31409915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12828724 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8291869 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 3034016 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3034016 — Surrogate Endpoint (SUR): Blood pressure
Study 29790415 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 2309640 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16753975 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9286741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2887190 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2887190 — Surrogate Endpoint (SUR): Blood pressure
Study 16875724 — Surrogate Endpoint (SUR): Blood pressure
Study 12954465 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 12954465 — Predictive Biomarker (PRD): MGAT1 mRNA
Genes: MGAT1; GGNT1; GLCT1; GLYT1; MGAT
Study 15365570 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 11239541 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7508194 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7508194 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7508194 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 19854114 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18435852 — Surrogate Endpoint (SUR): Blood pressure
Study 17158431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24887381 — Predictive Biomarker (PRD): NRM mRNA
Genes: NRM; NRM29; UNQ555/PRO1112
Study 22305998 — Surrogate Endpoint (SUR): Blood pressure
Study 19806530 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 11884902 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 2195013 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2931232 — Surrogate Endpoint (SUR): Blood pressure
Study 2011075 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2011075 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25896330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25896330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9692778 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28922340 — Surrogate Endpoint (SUR): Blood pressure
Study 23454404 — Surrogate Endpoint (SUR): Serum sodium
Study 16339157 — Predictive Biomarker (PRD): SDC1 mRNA
Genes: SDC1; SDC
Study 26325557 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26325557 — Surrogate Endpoint (SUR): Serum potassium
Study 22484413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21527115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18958842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12663295 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 8633815 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29554535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28718233 — Surrogate Endpoint (SUR): Blood pressure
Study 19549691 — Surrogate Endpoint (SUR): Serum creatinine
Study 16700815 — Surrogate Endpoint (SUR): Blood pressure
Study 9512843 — Predictive Biomarker (PRD): EBP mRNA
Genes: EBP
Study 23998910 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17198589 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 12595509 — Surrogate Endpoint (SUR): Serum creatinine
Study 1683196 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21742465 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17072689 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 10618560 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 24314907 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 8607684 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 8607684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8607684 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8607684 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22736737 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 20589733 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 20589733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20589733 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 20589733 — Safety Biomarker (SAF): Reactive oxygen species
Study 18330955 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10480626 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 6282790 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 9164822 — Surrogate Endpoint (SUR): Bone mineral density
Study 28034894 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 27485453 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20622657 — Surrogate Endpoint (SUR): Sperm parameters
Study 2953224 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2953224 — Surrogate Endpoint (SUR): Blood pressure
Study 18808338 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 16835748 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 823828 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 823828 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31934821 — Surrogate Endpoint (SUR): Blood pressure
Study 21472620 — Surrogate Endpoint (SUR): Serum testosterone
Study 17881186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24090588 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 21432860 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 14689411 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8799526 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 16490844 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3530417 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26118143 — Surrogate Endpoint (SUR): Blood pressure
Study 11408340 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9252801 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 29240541 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29240541 — Surrogate Endpoint (SUR): Serum testosterone
Study 22647783 — Surrogate Endpoint (SUR): Blood pressure
Study 8249851 — Surrogate Endpoint (SUR): Blood pressure
Study 18765698 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6850722 — Surrogate Endpoint (SUR): Blood pressure
Study 29182407 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 29182407 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 24799181 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 24799181 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9498512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9498512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22168642 — Surrogate Endpoint (SUR): Blood pressure
Study 22168642 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22168642 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23860961 — Surrogate Endpoint (SUR): Serum creatinine
Study 23860961 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16623075 — Surrogate Endpoint (SUR): Blood pressure
Study 29064872 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 29064872 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21427078 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 27142170 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 27142170 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 15678619 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 23199009 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14556865 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 9381549 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9381549 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9381549 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15504288 — Monitoring Biomarker (MOI): HBV DNA
Study 24101860 — Safety Biomarker (SAF): Hyaluronic acid
Study 20923537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20923537 — Surrogate Endpoint (SUR): Blood pressure
Study 17885297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23980349 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23980349 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 23980349 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23980349 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12809971 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16269641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2688405 — Surrogate Endpoint (SUR): Serum creatinine
Study 2688405 — Surrogate Endpoint (SUR): Serum potassium
Study 2688405 — Surrogate Endpoint (SUR): Blood pressure
Study 21050539 — Surrogate Endpoint (SUR): Blood pressure
Study 22983369 — Surrogate Endpoint (SUR): Blood pressure
Study 11864664 — Surrogate Endpoint (SUR): Blood pressure
Study 11864664 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7566021 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7566021 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31299087 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 28024935 — Surrogate Endpoint (SUR): Blood pressure
Study 16709386 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11776446 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 27092703 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 30233000 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 30233000 — Surrogate Endpoint (SUR): Serum creatinine
Study 11361048 — Predictive Biomarker (PRD): RNH1 mRNA
Genes: RNH1; PRI; RNH
Study 9732337 — Surrogate Endpoint (SUR): Blood pressure
Study 9732337 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17362049 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17362049 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9650129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31487546 — Surrogate Endpoint (SUR): Blood pressure
Study 11777176 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 2516523 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25771141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21584666 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1164334 — Surrogate Endpoint (SUR): Blood pressure
Study 31166706 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31166706 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31166706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26976659 — Surrogate Endpoint (SUR): Blood pressure
Study 26268362 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 23529166 — Surrogate Endpoint (SUR): Blood pressure
Study 21166600 — Surrogate Endpoint (SUR): Blood pressure
Study 21166600 — Surrogate Endpoint (SUR): Serum creatinine
Study 29398871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29398871 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29398871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12208797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30488367 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17364581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15068414 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8507888 — Monitoring Biomarker (MOI): HBV DNA
Study 28318938 — Surrogate Endpoint (SUR): Blood pressure
Study 12851604 — Surrogate Endpoint (SUR): Blood pressure
Study 25099464 — Surrogate Endpoint (SUR): Blood pressure
Study 2392793 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27272805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27272805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11890101 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 1014769 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 28548587 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 25479022 — Surrogate Endpoint (SUR): Blood pressure
Study 23771796 — Surrogate Endpoint (SUR): Bone mineral density
Study 25432467 — Surrogate Endpoint (SUR): Blood pressure
Study 9428558 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9428558 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7851857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30760190 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30760190 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 21411557 — Surrogate Endpoint (SUR): Bone mineral density
Study 19146606 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19146606 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 16831410 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16831410 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 27642077 — Predictive Biomarker (PRD): TACR1 mRNA
Genes: TACR1; NK1R; TAC1R
Study 30341095 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17468196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1