TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9148019 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 9148019 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18653145 — Surrogate Endpoint (SUR): Blood pressure
Study 2178992 — Surrogate Endpoint (SUR): Blood pressure
Study 21690592 — Surrogate Endpoint (SUR): Blood pressure
Study 9927370 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 7571476 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7571476 — Surrogate Endpoint (SUR): Blood pressure
Study 18319227 — Predictive Biomarker (PRD): PCSK7 mRNA
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 8937605 — Surrogate Endpoint (SUR): Blood pressure
Study 6487462 — Surrogate Endpoint (SUR): Blood pressure
Study 26653112 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18477422 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 12370843 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26425700 — Predictive Biomarker (PRD): HOXD10 mRNA
Genes: HOXD10; HOX4D; HOX4E
Study 26425700 — Predictive Biomarker (PRD): PAX9 mRNA
Genes: PAX9
Study 26425700 — Predictive Biomarker (PRD): PTPRN2 mRNA
Genes: PTPRN2; KIAA0387
Study 26425700 — Predictive Biomarker (PRD): STAG3 mRNA
Genes: STAG3
Study 26425700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 26425700 — Monitoring Biomarker (MOI): Cell-free DNA
Study 23305245 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 23305245 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 24966150 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24966150 — Safety Biomarker (SAF): IL-6 and IL-10
Study 28768654 — Predictive Biomarker (PRD): PPM1K mRNA
Genes: PPM1K; PP2CM
Study 24584605 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 24584605 — Surrogate Endpoint (SUR): Serum calcium
Study 21257028 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21257028 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21257028 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21257028 — Surrogate Endpoint (SUR): Blood pressure
Study 9950657 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 2175584 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8925479 — Predictive Biomarker (PRD): AGL mRNA
Genes: AGL; GDE
Study 8925479 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28742614 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22515638 — Surrogate Endpoint (SUR): Blood pressure
Study 16166415 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12897994 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 12897994 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10539780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1360803 — Surrogate Endpoint (SUR): Blood pressure
Study 6386007 — Surrogate Endpoint (SUR): Blood pressure
Study 24876916 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 7933492 — Surrogate Endpoint (SUR): Blood pressure
Study 22449332 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22449332 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 22449332 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 20807664 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1706015 — Surrogate Endpoint (SUR): Blood pressure
Study 24598293 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8589000 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2474480 — Monitoring Biomarker (MOI): HBV DNA
Study 28482137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26112278 — Surrogate Endpoint (SUR): Blood pressure
Study 19827645 — Surrogate Endpoint (SUR): Blood pressure
Study 15313360 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 8077329 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 7437173 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24249359 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 24249359 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 17151592 — Surrogate Endpoint (SUR): Blood pressure
Study 9625273 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27207203 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18331364 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 18331364 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 11548979 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 11548979 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9661593 — Surrogate Endpoint (SUR): Bone mineral density
Study 8310510 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9105222 — Surrogate Endpoint (SUR): Blood pressure
Study 30815998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27184139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 20600255 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9376994 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9376994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8404785 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24165906 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15464496 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 9197354 — Surrogate Endpoint (SUR): Blood pressure
Study 9197354 — Surrogate Endpoint (SUR): Serum creatinine
Study 18469202 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 16614984 — Surrogate Endpoint (SUR): Blood pressure
Study 30562195 — Predictive Biomarker (PRD): RIT1 mRNA
Genes: RIT1; RIBB; RIT; ROC1
Study 30562195 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26537053 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23524843 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 16234518 — Predictive Biomarker (PRD): Hormone receptor
Study 16234518 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2149510 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22547421 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21276222 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 14720270 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 14720270 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8505831 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15839438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28853228 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28853228 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26458536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 22614767 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12724019 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 8726183 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 8726183 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 22267768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9311442 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 17087951 — Monitoring Biomarker (MOI): HBV DNA
Study 11123371 — Surrogate Endpoint (SUR): Blood pressure
Study 30339194 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 30339194 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30339194 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 28103611 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28103611 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28103611 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 19728370 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23060625 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 21198719 — Surrogate Endpoint (SUR): Serum creatinine
Study 10851830 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2455106 — Surrogate Endpoint (SUR): Blood pressure
Study 31498109 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29071968 — Surrogate Endpoint (SUR): Blood pressure
Study 29298077 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 21695893 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15333424 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26969754 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 26969754 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25394430 — Surrogate Endpoint (SUR): Blood pressure
Study 14572578 — Surrogate Endpoint (SUR): Bone mineral density
Study 9412432 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9412432 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 29128417 — Surrogate Endpoint (SUR): Blood pressure
Study 26847832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20113315 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20113315 — Surrogate Endpoint (SUR): Blood pressure
Study 17030155 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17030155 — Surrogate Endpoint (SUR): Blood pressure
Study 15853986 — Monitoring Biomarker (MOI): HBV DNA
Study 10220795 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 10220795 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 23567655 — Surrogate Endpoint (SUR): Serum testosterone
Study 20619353 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17656469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16807281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12891248 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12891248 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8950722 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 1549214 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20435194 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 2145407 — Surrogate Endpoint (SUR): Blood pressure
Study 394868 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 7965276 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7965276 — Surrogate Endpoint (SUR): Blood pressure
Study 10579750 — Surrogate Endpoint (SUR): Blood pressure
Study 8571305 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8571305 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2346518 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2346518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20110160 — Surrogate Endpoint (SUR): Blood pressure
Study 29124494 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25283552 — Predictive Biomarker (PRD): GNS mRNA
Genes: GNS
Study 22445512 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20159906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20159906 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9064947 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 20413969 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 18343177 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 12647599 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12647599 — Surrogate Endpoint (SUR): Blood pressure
Study 24848642 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 12926181 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 12926181 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 12926181 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 9426829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9426829 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9426829 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 9426829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8535656 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19332233 — Surrogate Endpoint (SUR): Serum calcium
Study 12631049 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11205196 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 12123126 — Surrogate Endpoint (SUR): Serum creatinine
Study 10220643 — Surrogate Endpoint (SUR): Blood pressure
Study 8558750 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17208898 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26137564 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 26137564 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 26137564 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23314982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23314982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23314982 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23314982 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23314982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23314982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22466027 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 15266308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15266308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10084558 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 379722 — Surrogate Endpoint (SUR): Blood pressure
Study 1483069 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 30959227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29107324 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 26015451 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26015451 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 22169699 — Safety Biomarker (SAF): Hyaluronic acid
Study 29870029 — Surrogate Endpoint (SUR): Blood pressure
Study 26936907 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 2921077 — Surrogate Endpoint (SUR): Blood pressure
Study 31906754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29542251 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26684819 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6538844 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 29486514 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22209773 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8622105 — Surrogate Endpoint (SUR): Serum creatinine
Study 31910850 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 31910850 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31910850 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31910850 — Surrogate Endpoint (SUR): Serum creatinine
Study 23313581 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22021025 — Surrogate Endpoint (SUR): Blood pressure
Study 22021025 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19307466 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19307466 — Surrogate Endpoint (SUR): Serum potassium
Study 9512836 — Surrogate Endpoint (SUR): Bone mineral density
Study 31956037 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 31956037 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31956037 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 24262291 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 22128078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30192751 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 24775575 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 20437555 — Surrogate Endpoint (SUR): Blood pressure
Study 30607570 — Safety Biomarker (SAF): Hyaluronic acid
Study 12011122 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29040445 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 8673548 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29342199 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 29342199 — Predictive Biomarker (PRD): SLC47A2 mRNA
Genes: SLC47A2; MATE2
Study 29342199 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 26774115 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26774115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26774115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26774115 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26774115 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25388940 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11524318 — Surrogate Endpoint (SUR): Blood pressure
Study 8512675 — Surrogate Endpoint (SUR): Blood pressure
Study 2962417 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29692602 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22899814 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21995692 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21995692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12725542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9109868 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 3995516 — Surrogate Endpoint (SUR): Blood pressure
Study 31250602 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 26808136 — Surrogate Endpoint (SUR): Serum creatinine
Study 26808136 — Surrogate Endpoint (SUR): Blood pressure
Study 16279901 — Monitoring Biomarker (MOI): HBV DNA
Study 16885196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16885196 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 15691277 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15691277 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 15691277 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 15691277 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15691277 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12019929 — Surrogate Endpoint (SUR): Blood pressure
Study 10721643 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10721643 — Surrogate Endpoint (SUR): Serum creatinine
Study 21401833 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21401833 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10642897 — Safety Biomarker (SAF): Reactive oxygen species
Study 30121944 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27306517 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22526147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16630999 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16630999 — Surrogate Endpoint (SUR): Serum sodium
Study 2008876 — Surrogate Endpoint (SUR): Blood pressure
Study 29231589 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 26757793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20436440 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 1916494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30514775 — Monitoring Biomarker (MOI): Circulating tumor DNA