TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26437613 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20346304 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31190621 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 31190621 — Predictive Biomarker (PRD): Hormone receptor
Study 31390590 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 15074084 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 2822879 — Surrogate Endpoint (SUR): Blood pressure
Study 29862395 — Surrogate Endpoint (SUR): Blood pressure
Study 11121919 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9125681 — Surrogate Endpoint (SUR): Blood pressure
Study 3689613 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28620941 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23786500 — Surrogate Endpoint (SUR): Blood pressure
Study 3931943 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27368012 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 25053182 — Surrogate Endpoint (SUR): Serum creatinine
Study 30965275 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30965275 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 30965275 — Safety Biomarker (SAF): BDNF
Study 26091197 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 23435530 — Surrogate Endpoint (SUR): Sperm parameters
Study 11061530 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11061530 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11061530 — Surrogate Endpoint (SUR): Bone mineral density
Study 2573364 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26049123 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16769471 — Surrogate Endpoint (SUR): Blood pressure
Study 12897375 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 2868573 — Surrogate Endpoint (SUR): Blood pressure
Study 27863207 — Surrogate Endpoint (SUR): Serum testosterone
Study 24190902 — Surrogate Endpoint (SUR): Blood pressure
Study 24390887 — Surrogate Endpoint (SUR): Blood pressure
Study 22848481 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22848481 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 19276983 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15359921 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 11176735 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11176735 — Surrogate Endpoint (SUR): Blood pressure
Study 9608581 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 15486848 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26897130 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25690407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24136138 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20504977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20504977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20504977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20504977 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15717460 — Surrogate Endpoint (SUR): Blood pressure
Study 6342165 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 6342165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12393661 — Safety Biomarker (SAF): Interleukin 1
Study 12393661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12393661 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10214857 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24170325 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 2533187 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 2533187 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 972133 — Surrogate Endpoint (SUR): Blood pressure
Study 31174403 — Surrogate Endpoint (SUR): Serum calcium
Study 23588240 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 15618599 — Surrogate Endpoint (SUR): Bone mineral density
Study 10360370 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24354651 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 23001587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8004839 — Surrogate Endpoint (SUR): Blood pressure
Study 25665096 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19413407 — Safety Biomarker (SAF): DRD2
Study 17892999 — Surrogate Endpoint (SUR): Blood pressure
Study 14706203 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 14706203 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11685384 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31313547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27928454 — Surrogate Endpoint (SUR): Serum calcium
Study 27928454 — Surrogate Endpoint (SUR): Blood pressure
Study 27928454 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19624730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18370544 — Surrogate Endpoint (SUR): Blood pressure
Study 29071946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19563287 — Predictive Biomarker (PRD): TKT mRNA
Genes: TKT
Study 7797808 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2150640 — Surrogate Endpoint (SUR): Blood pressure
Study 533742 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30829609 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 15347773 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15347773 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2789447 — Surrogate Endpoint (SUR): Blood pressure
Study 6721127 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 25084070 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20506504 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12547850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12547850 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8618160 — Surrogate Endpoint (SUR): Bone mineral density
Study 20723636 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12358339 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 23416800 — Surrogate Endpoint (SUR): Blood pressure
Study 19568709 — Surrogate Endpoint (SUR): Serum testosterone
Study 14753131 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 29909091 — Safety Biomarker (SAF): UGT1A1
Genes: UGT1A
Study 23833854 — Surrogate Endpoint (SUR): Blood pressure
Study 18756940 — Surrogate Endpoint (SUR): Serum creatinine
Study 27378823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16168630 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 12689685 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12689685 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 12689685 — Surrogate Endpoint (SUR): Bone mineral density
Study 12689685 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18039987 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18039987 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30150014 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24679550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24679550 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8878253 — Surrogate Endpoint (SUR): Blood pressure
Study 22466910 — Surrogate Endpoint (SUR): Serum creatinine
Study 9204220 — Surrogate Endpoint (SUR): Blood pressure
Study 7957457 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26585988 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 26585988 — Surrogate Endpoint (SUR): Bone mineral density
Study 25581656 — Predictive Biomarker (PRD): GRIK1 mRNA
Genes: GRIK1; GLUR5
Study 10700443 — Safety Biomarker (SAF): Reactive oxygen species
Study 27226182 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 27226182 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22325903 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 17418730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12572376 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 23298374 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21572305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19620495 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19620495 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19620495 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19620495 — Predictive Biomarker (PRD): Hormone receptor
Study 9165550 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1375485 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29703793 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 19261825 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 19261825 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19261825 — Surrogate Endpoint (SUR): Serum calcium
Study 1103207 — Surrogate Endpoint (SUR): Blood pressure
Study 12477995 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7701450 — Surrogate Endpoint (SUR): Serum potassium
Study 2634111 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2634111 — Surrogate Endpoint (SUR): Blood pressure
Study 24690589 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28244897 — Surrogate Endpoint (SUR): Blood pressure
Study 23721363 — Surrogate Endpoint (SUR): Blood pressure
Study 11583718 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29069370 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29069370 — Predictive Biomarker (PRD): Hormone receptor
Study 12527500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12527500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12527500 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9703374 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 10702886 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 2009147 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2009147 — Surrogate Endpoint (SUR): Blood pressure
Study 29027667 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 29027667 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 29027667 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29027667 — Predictive Biomarker (PRD): CD244 mRNA
Genes: CD244; 2B4
Study 10636472 — Surrogate Endpoint (SUR): Serum testosterone
Study 26520926 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26520926 — Surrogate Endpoint (SUR): Bone mineral density
Study 16891758 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16891758 — Surrogate Endpoint (SUR): Blood pressure
Study 30219823 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27630212 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16843192 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16843192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11164436 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25154706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19368899 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19368899 — Safety Biomarker (SAF): BDNF
Study 16600924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16600924 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8725679 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15725943 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15725943 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29990690 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27604335 — Surrogate Endpoint (SUR): Serum creatinine
Study 25439449 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23110676 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 22944145 — Predictive Biomarker (PRD): UBC mRNA
Genes: UBC
Study 16424843 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 12856386 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 10212170 — Surrogate Endpoint (SUR): Blood pressure
Study 31124147 — Surrogate Endpoint (SUR): Probing pocket depth
Study 28701288 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26664151 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29389692 — Predictive Biomarker (PRD): SUCO mRNA
Genes: SUCO; C1orf9; CH1; OPT; SLP1
Study 26481764 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 12097688 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12097688 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12097688 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10424318 — Surrogate Endpoint (SUR): Blood pressure
Study 24428733 — Predictive Biomarker (PRD): CHRNA4 mRNA
Genes: CHRNA4; NACRA4
Study 17636280 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 17636280 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 14657616 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3401284 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 29165355 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29165355 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29165355 — Surrogate Endpoint (SUR): Blood pressure
Study 29165355 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 24304733 — Surrogate Endpoint (SUR): Blood pressure
Study 16983180 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 23546172 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 19608589 — Surrogate Endpoint (SUR): Blood pressure
Study 22188532 — Surrogate Endpoint (SUR): Blood pressure
Study 1899365 — Predictive Biomarker (PRD): TIE1 mRNA
Genes: TIE1; TIE
Study 31051504 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26802147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20236788 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 20236788 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20236788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17639302 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 9649710 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 9649710 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 28836279 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24163397 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15450559 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9832480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9832480 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31642586 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31642586 — Surrogate Endpoint (SUR): Bone mineral density
Study 31272568 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31272568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25681059 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 25681059 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 25681059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8148217 — Surrogate Endpoint (SUR): Blood pressure
Study 2659002 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23213101 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19887477 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19887477 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 19887477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19887477 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 19887477 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 11421999 — Surrogate Endpoint (SUR): Blood pressure
Study 8482046 — Surrogate Endpoint (SUR): Blood pressure
Study 20171424 — Surrogate Endpoint (SUR): Blood pressure
Study 18394874 — Surrogate Endpoint (SUR): Blood pressure
Study 22729307 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15875154 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 15875154 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 12519867 — Surrogate Endpoint (SUR): Blood pressure
Study 12519867 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31928076 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31928076 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 31928076 — Predictive Biomarker (PRD): IL16 mRNA
Genes: IL16
Study 31928076 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31928076 — Safety Biomarker (SAF): IL16
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 30630783 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 6410898 — Surrogate Endpoint (SUR): Serum calcium
Study 29871849 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 9279199 — Surrogate Endpoint (SUR): Blood pressure
Study 12971419 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 8917741 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 26382279 — Monitoring Biomarker (MOI): HBV DNA
Study 24510496 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 20064185 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 20950940 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 17084249 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17084249 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17084249 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17084249 — Surrogate Endpoint (SUR): Blood pressure
Study 9280206 — Surrogate Endpoint (SUR): Blood pressure
Study 21520588 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18623165 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 8157946 — Surrogate Endpoint (SUR): Blood pressure
Study 25106447 — Predictive Biomarker (PRD): DARS1 mRNA
Genes: DARS1; DARS; PIG40
Study 11850090 — Surrogate Endpoint (SUR): Blood pressure
Study 2660893 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30676666 — Predictive Biomarker (PRD): HADHA mRNA
Genes: HADHA; HADH
Study 30676666 — Predictive Biomarker (PRD): QDPR mRNA
Genes: QDPR; DHPR; SDR33C1
Study 29911772 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 3096633 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 3096633 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 3096633 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3096633 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21919543 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19883295 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 19883295 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11734672 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 11734672 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11734672 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8060578 — Surrogate Endpoint (SUR): Blood pressure
Study 8060578 — Surrogate Endpoint (SUR): Serum sodium
Study 2054714 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 24450390 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24450390 — Surrogate Endpoint (SUR): Blood pressure
Study 21714897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1