TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20574648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20101919 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15073451 — Surrogate Endpoint (SUR): Serum creatinine
Study 3548735 — Surrogate Endpoint (SUR): Blood pressure
Study 23793042 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10724053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3926135 — Surrogate Endpoint (SUR): Blood pressure
Study 20668455 — Surrogate Endpoint (SUR): Blood pressure
Study 20668455 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11451592 — Predictive Biomarker (PRD): SCARA3 mRNA
Genes: SCARA3; CSR
Study 28880972 — Predictive Biomarker (PRD): TPBG mRNA
Genes: TPBG; 5T4
Study 9921571 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 574098 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27916987 — Predictive Biomarker (PRD): LGALS1 mRNA
Genes: LGALS1
Study 27916987 — Predictive Biomarker (PRD): ENO1 mRNA
Genes: ENO1; ENO1L1; MBPB1; MPB1
Study 27916987 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 19954721 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19954721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19954721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14722327 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14722327 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 14722327 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2925842 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 2925842 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22956434 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17145722 — Surrogate Endpoint (SUR): Blood pressure
Study 15307550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15307550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15307550 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8405743 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 27049100 — Safety Biomarker (SAF): Hyaluronic acid
Study 20516658 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 12577372 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12577372 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 22209741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22152723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22152723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20297714 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 15208585 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 24348043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24348043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24348043 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24348043 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 21513530 — Surrogate Endpoint (SUR): Blood pressure
Study 12946764 — Surrogate Endpoint (SUR): Serum sodium
Study 12946764 — Surrogate Endpoint (SUR): Serum calcium
Study 2422004 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7957532 — Surrogate Endpoint (SUR): Blood pressure
Study 3300711 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12029205 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7573090 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7573090 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19728932 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 19728932 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 7907174 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20530522 — Surrogate Endpoint (SUR): Bone mineral density
Study 16181530 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8696067 — Surrogate Endpoint (SUR): Blood pressure
Study 30787659 — Surrogate Endpoint (SUR): Blood pressure
Study 25128877 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25128877 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25128877 — Safety Biomarker (SAF): BDNF
Study 25128877 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18160764 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3906227 — Surrogate Endpoint (SUR): Blood pressure
Study 31690537 — Surrogate Endpoint (SUR): Blood pressure
Study 23390092 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17705990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 8555550 — Surrogate Endpoint (SUR): Blood pressure
Study 28428736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12661145 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11479155 — Surrogate Endpoint (SUR): Serum creatinine
Study 519960 — Surrogate Endpoint (SUR): Blood pressure
Study 31743071 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28584187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28629293 — Surrogate Endpoint (SUR): Blood pressure
Study 24934402 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 17868757 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 14551893 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8899386 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 20152998 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17043639 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 17043639 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 11371279 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 30202946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30202946 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19332456 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9631846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28937272 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 23362019 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23362019 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23362019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21599573 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10862930 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 8904521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31056884 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 25308927 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23911536 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21736808 — Surrogate Endpoint (SUR): Bone mineral density
Study 22513081 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 22513081 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 24468797 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22629839 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22629839 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 20173440 — Predictive Biomarker (PRD): MSN mRNA
Genes: MSN
Study 8655981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1515957 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1515957 — Surrogate Endpoint (SUR): Blood pressure
Study 22248028 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 18584415 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18584415 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16198422 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 12174408 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12174408 — Surrogate Endpoint (SUR): Blood pressure
Study 28338503 — Surrogate Endpoint (SUR): Blood pressure
Study 18463427 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18463427 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16415635 — Surrogate Endpoint (SUR): Blood pressure
Study 30137647 — Surrogate Endpoint (SUR): Bone mineral density
Study 27903247 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 27903247 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 27903247 — Surrogate Endpoint (SUR): Pathological complete response
Study 15632815 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10188899 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 30859961 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 28981764 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 22814294 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 19236279 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10435372 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 8771219 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9740601 — Surrogate Endpoint (SUR): Blood pressure
Study 7979291 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28829876 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18852529 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18852529 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18852529 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31136659 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 31136659 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31136659 — Surrogate Endpoint (SUR): Blood pressure
Study 28432266 — Surrogate Endpoint (SUR): Blood pressure
Study 15315996 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25071111 — Predictive Biomarker (PRD): Hormone receptor
Study 20113387 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 18204347 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 30149537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18156661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12878366 — Surrogate Endpoint (SUR): Blood pressure
Study 12878366 — Surrogate Endpoint (SUR): Serum sodium
Study 9403744 — Surrogate Endpoint (SUR): Serum creatinine
Study 8353025 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 15769683 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 9316463 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9316463 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22309902 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 18388031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18388031 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18388031 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24641883 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24641883 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 24984529 — Surrogate Endpoint (SUR): Blood pressure
Study 15986266 — Surrogate Endpoint (SUR): Serum creatinine
Study 31911641 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 22659656 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22659656 — Surrogate Endpoint (SUR): Blood pressure
Study 19070356 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7636393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7636393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7636393 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 369673 — Surrogate Endpoint (SUR): Blood pressure
Study 15496603 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 15496603 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20641058 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20641058 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 20641058 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 11770189 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11770189 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11770189 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26498404 — Surrogate Endpoint (SUR): Blood pressure
Study 18583430 — Surrogate Endpoint (SUR): Blood pressure
Study 14734060 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9821034 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 9821034 — Surrogate Endpoint (SUR): Blood pressure
Study 7651068 — Surrogate Endpoint (SUR): Serum creatinine
Study 29026141 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31181728 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 28207536 — Surrogate Endpoint (SUR): Blood pressure
Study 27547757 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25112085 — Surrogate Endpoint (SUR): Blood pressure
Study 23363065 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10789668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2779095 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2779095 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21800009 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 21036880 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18408077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18408077 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31706911 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 11443537 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11443537 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11443537 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2837262 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28893130 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 12728215 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10789595 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9162611 — Surrogate Endpoint (SUR): Blood pressure
Study 1637574 — Surrogate Endpoint (SUR): Serum calcium
Study 1637574 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 11932310 — Surrogate Endpoint (SUR): Blood pressure
Study 26217065 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17142929 — Surrogate Endpoint (SUR): Bone mineral density
Study 22081474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17992069 — Surrogate Endpoint (SUR): Blood pressure
Study 7019703 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21185503 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21185503 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19552619 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10023325 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 29334992 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28549471 — Surrogate Endpoint (SUR): Blood pressure
Study 30073471 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 17183021 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 7509383 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21358538 — Surrogate Endpoint (SUR): Blood pressure
Study 23479321 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23479321 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28150513 — Surrogate Endpoint (SUR): Bone mineral density
Study 24968129 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 17699475 — Surrogate Endpoint (SUR): Serum creatinine
Study 8984133 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8984133 — Surrogate Endpoint (SUR): Blood pressure
Study 8984133 — Surrogate Endpoint (SUR): Serum uric acid
Study 1665179 — Surrogate Endpoint (SUR): Serum potassium
Study 29915931 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 29915931 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 29915931 — Predictive Biomarker (PRD): PLOD1 mRNA
Genes: PLOD1; LLH; PLOD
Study 23060628 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 6443576 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 6443576 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24593826 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9625399 — Surrogate Endpoint (SUR): Blood pressure
Study 29741913 — Predictive Biomarker (PRD): NOVA2 mRNA
Genes: NOVA2; ANOVA; NOVA3
Study 15877991 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15877991 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15877991 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12706322 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12706322 — Surrogate Endpoint (SUR): Blood pressure
Study 12706322 — Surrogate Endpoint (SUR): Serum creatinine
Study 6111525 — Surrogate Endpoint (SUR): Blood pressure
Study 31764009 — Surrogate Endpoint (SUR): Blood pressure
Study 21560012 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 7962342 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 26241948 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23252875 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 23252875 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 8884861 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 1728634 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 24578449 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24578449 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10463681 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 7969673 — Surrogate Endpoint (SUR): Urinary oxalate
Study 8872691 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 8872691 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8872691 — Surrogate Endpoint (SUR): Blood pressure
Study 21593352 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 16834836 — Surrogate Endpoint (SUR): Blood pressure
Study 25170994 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22648289 — Surrogate Endpoint (SUR): Serum uric acid
Study 22648289 — Surrogate Endpoint (SUR): Serum creatinine
Study 21753777 — Surrogate Endpoint (SUR): Blood pressure
Study 12757533 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10482155 — Surrogate Endpoint (SUR): Blood pressure
Study 1656149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6633596 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28651249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28651249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15649285 — Surrogate Endpoint (SUR): Bone mineral density
Study 27353237 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 11293738 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24244656 — Safety Biomarker (SAF): Reactive oxygen species
Study 21124314 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 21124314 — Predictive Biomarker (PRD): SLC47A2 mRNA
Genes: SLC47A2; MATE2
Study 21124314 — Surrogate Endpoint (SUR): Serum creatinine
Study 17162316 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18302459 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 10907363 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10907363 — Surrogate Endpoint (SUR): Blood pressure