TrialPanorama/TrialPanorama-database huggingface dataset:
Study 3471304 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 14557449 — Surrogate Endpoint (SUR): Bone mineral density
Study 11099619 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27009620 — Surrogate Endpoint (SUR): Blood pressure
Study 27009620 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20142543 — Surrogate Endpoint (SUR): Blood pressure
Study 20142543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10703876 — Surrogate Endpoint (SUR): Blood pressure
Study 1718158 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 9227164 — Surrogate Endpoint (SUR): Bone mineral density
Study 7958497 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 7958497 — Surrogate Endpoint (SUR): Blood pressure
Study 30977767 — Surrogate Endpoint (SUR): Serum sodium
Study 30977767 — Surrogate Endpoint (SUR): Blood pressure
Study 12796026 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12796026 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 6941637 — Surrogate Endpoint (SUR): Blood pressure
Study 18244953 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 12591752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8671971 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 8671971 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8671971 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1768565 — Surrogate Endpoint (SUR): Blood pressure
Study 8500867 — Surrogate Endpoint (SUR): Blood pressure
Study 30789808 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 30789808 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 18294323 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 3516077 — Surrogate Endpoint (SUR): Serum creatinine
Study 19699885 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11873095 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8141163 — Surrogate Endpoint (SUR): Blood pressure
Study 1920342 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 26684708 — Surrogate Endpoint (SUR): Blood pressure
Study 19386744 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 16690701 — Predictive Biomarker (PRD): PLN mRNA
Genes: PLN; PLB
Study 26286662 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 26286662 — Predictive Biomarker (PRD): MARCKS mRNA
Genes: MARCKS; MACS; PRKCSL
Study 2904373 — Surrogate Endpoint (SUR): Blood pressure
Study 11443568 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 11443568 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 31625947 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 19023677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15017629 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9347286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 30944103 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 24687088 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 15973964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15973964 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18593759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11453961 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 7687717 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24217262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16525677 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 16525677 — Safety Biomarker (SAF): IL-6 and IL-10
Study 30111284 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23078110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23078110 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 23078110 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23078110 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 9268188 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9268188 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9268188 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10588299 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1713753 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1713753 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31409388 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 19247842 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 19247842 — Surrogate Endpoint (SUR): Blood pressure
Study 15657667 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22865266 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 22865266 — Predictive Biomarker (PRD): TNC mRNA
Genes: TNC; HXB
Study 8514613 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8514613 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8514613 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8514613 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27088277 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10439886 — Surrogate Endpoint (SUR): Blood pressure
Study 7876852 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 18491 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 26171113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26171113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26171113 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 6147080 — Surrogate Endpoint (SUR): Blood pressure
Study 27238057 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 9704788 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 29398646 — Predictive Biomarker (PRD): SUB1 mRNA
Genes: SUB1; PC4; RPO2TC1
Study 26823503 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 19171717 — Surrogate Endpoint (SUR): Blood pressure
Study 18940490 — Surrogate Endpoint (SUR): Blood pressure
Study 12444941 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10702653 — Surrogate Endpoint (SUR): Blood pressure
Study 6184569 — Surrogate Endpoint (SUR): Blood pressure
Study 6184569 — Surrogate Endpoint (SUR): Serum creatinine
Study 30287324 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30287324 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11351771 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 11351771 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9684796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9684796 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9684796 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7802318 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29432877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27473162 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24521425 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15702341 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 25884155 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 3335117 — Surrogate Endpoint (SUR): Blood pressure
Study 10994902 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19942984 — Surrogate Endpoint (SUR): Blood pressure
Study 9576634 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24103043 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24103043 — Surrogate Endpoint (SUR): Blood pressure
Study 10759821 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9322481 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 26967831 — Surrogate Endpoint (SUR): Blood pressure
Study 20156908 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20156908 — Predictive Biomarker (PRD): Hormone receptor
Study 681543 — Surrogate Endpoint (SUR): Blood pressure
Study 31053619 — Surrogate Endpoint (SUR): Blood pressure
Study 17132719 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 29304245 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 29304245 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 19440326 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16477653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16477653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16477653 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 16477653 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30193001 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19660597 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23205751 — Surrogate Endpoint (SUR): Blood pressure
Study 27021514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22945604 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 19951722 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19951722 — Surrogate Endpoint (SUR): Blood pressure
Study 18191521 — Surrogate Endpoint (SUR): Serum creatinine
Study 30790446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23906656 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18503138 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 17027358 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 12551795 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8254650 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28884881 — Surrogate Endpoint (SUR): Bone mineral density
Study 30700069 — Surrogate Endpoint (SUR): Bone mineral density
Study 15488868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15488868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15488868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3061819 — Surrogate Endpoint (SUR): Blood pressure
Study 30088288 — Surrogate Endpoint (SUR): Bone mineral density
Study 12817175 — Surrogate Endpoint (SUR): Blood pressure
Study 25509895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21911650 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study 20089951 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9661575 — Surrogate Endpoint (SUR): Blood pressure
Study 20505749 — Surrogate Endpoint (SUR): Blood pressure
Study 8018112 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 8018112 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1031487 — Surrogate Endpoint (SUR): Blood pressure
Study 31932495 — Predictive Biomarker (PRD): NDRG1 mRNA
Genes: NDRG1; CAP43; DRG1; RTP
Study 29590007 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18755584 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 12490967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12490967 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 12490967 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12490967 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12490967 — Surrogate Endpoint (SUR): Serum creatinine
Study 31481084 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 16729379 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 14673543 — Surrogate Endpoint (SUR): Serum potassium
Study 28651304 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28651304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28651304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26252195 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 19738166 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19738166 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19738166 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 19738166 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 16827066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3463571 — Surrogate Endpoint (SUR): Probing pocket depth
Study 26917604 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 24614693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23512638 — Safety Biomarker (SAF): Interleukin 12
Study 15515187 — Surrogate Endpoint (SUR): Blood pressure
Study 29452204 — Monitoring Biomarker (MOI): HBV DNA
Study 22592102 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 24026478 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7697476 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2192696 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 2192696 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31528100 — Monitoring Biomarker (MOI): HBV DNA
Study 10826397 — Surrogate Endpoint (SUR): Blood pressure
Study 25689953 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 15622367 — Surrogate Endpoint (SUR): Serum creatinine
Study 29172403 — Surrogate Endpoint (SUR): Serum creatinine
Study 11230476 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 30788847 — Predictive Biomarker (PRD): THEMIS mRNA
Genes: THEMIS; C6orf190; C6orf207
Study 22384544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22384544 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 25047762 — Predictive Biomarker (PRD): ALDH1A1 mRNA
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study 18757085 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18757085 — Surrogate Endpoint (SUR): Blood pressure
Study 10558453 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31428820 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31428820 — Surrogate Endpoint (SUR): Pathological complete response
Study 16723518 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 8015504 — Surrogate Endpoint (SUR): Blood pressure
Study 2597712 — Surrogate Endpoint (SUR): Blood pressure
Study 27698953 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27698953 — Safety Biomarker (SAF): Reactive oxygen species
Study 27698953 — Safety Biomarker (SAF): Cytochrome c
Study 17140647 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17140647 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17140647 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17140647 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 28923138 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 15111763 — Predictive Biomarker (PRD): Hormone receptor
Study 11230723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23288553 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 21275549 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2853934 — Surrogate Endpoint (SUR): Serum testosterone
Study 29694384 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 10769525 — Surrogate Endpoint (SUR): Blood pressure
Study 3214682 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 14598189 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 14598189 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 8479126 — Surrogate Endpoint (SUR): Serum creatinine
Study 21170205 — Surrogate Endpoint (SUR): Blood pressure
Study 17684475 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17684475 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 31612147 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29443664 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 27908454 — Predictive Biomarker (PRD): Hormone receptor
Study 22422103 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1093758 — Surrogate Endpoint (SUR): Blood pressure
Study 1093758 — Surrogate Endpoint (SUR): Serum uric acid
Study 1093758 — Surrogate Endpoint (SUR): Serum potassium
Study 1093758 — Surrogate Endpoint (SUR): Serum creatinine
Study 27766711 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 27766711 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 12624570 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22874536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22874536 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22874536 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 22874536 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study 22874536 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 22874536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11858475 — Surrogate Endpoint (SUR): Bone mineral density
Study 25581063 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17352768 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17352768 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2535678 — Surrogate Endpoint (SUR): Blood pressure
Study 28529147 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23760736 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 12665914 — Monitoring Biomarker (MOI): HBV DNA
Study 8600607 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8600607 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8600607 — Surrogate Endpoint (SUR): Blood pressure
Study 2510562 — Surrogate Endpoint (SUR): Blood pressure
Study 15647969 — Surrogate Endpoint (SUR): Bone mineral density
Study 25775686 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study 15475141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23884391 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18481390 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 1312888 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 29418016 — Surrogate Endpoint (SUR): Bone mineral density
Study 12173072 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25461393 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25461393 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 25461393 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25461393 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 10772372 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17003082 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3359548 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15541014 — Surrogate Endpoint (SUR): Blood pressure
Study 8491246 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8491246 — Surrogate Endpoint (SUR): Blood pressure
Study 23373662 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23373662 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 9796841 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 871634 — Surrogate Endpoint (SUR): Blood pressure
Study 30664736 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25290091 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 25290091 — Predictive Biomarker (PRD): IGF2 mRNA
Genes: IGF2; PP1446
Study 12851279 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 8902992 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8902992 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30137664 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24467549 — Surrogate Endpoint (SUR): Serum uric acid
Study 15857205 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7838634 — Surrogate Endpoint (SUR): Serum sodium
Study 19081265 — Surrogate Endpoint (SUR): Blood pressure
Study 15196297 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 15196297 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 1702449 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 1702449 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 1702449 — Predictive Biomarker (PRD): GCSAM mRNA
Genes: GCSAM; GAL; GCET2