TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30611727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30611727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25688779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 531541 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31812890 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 28528354 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 21464293 — Surrogate Endpoint (SUR): Bone mineral density
Study 9360528 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27022118 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29150046 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26063693 — Surrogate Endpoint (SUR): Blood pressure
Study 22411387 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15208597 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 15208597 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 15208597 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 15208597 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 7960017 — Surrogate Endpoint (SUR): Blood pressure
Study 29144993 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29144993 — Surrogate Endpoint (SUR): Serum testosterone
Study 24515352 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 20647284 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10825519 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 31727910 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 25543679 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20193310 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16210717 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29371479 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 6368874 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30827470 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19889809 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9426992 — Surrogate Endpoint (SUR): Blood pressure
Study 31613965 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22198589 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 11502234 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2963742 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26714488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11804430 — Surrogate Endpoint (SUR): Serum testosterone
Study 26077237 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 26077237 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26077237 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18299548 — Surrogate Endpoint (SUR): Blood pressure
Study 16518424 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 10755495 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 13680286 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 13680286 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 26771888 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26771888 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 26771888 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26771888 — Predictive Biomarker (PRD): RNASEL mRNA
Genes: RNASEL; RNS4
Study 26771888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22934754 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17234653 — Surrogate Endpoint (SUR): Blood pressure
Study 29433562 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29433562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27455955 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15966464 — Surrogate Endpoint (SUR): Blood pressure
Study 22556176 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22556176 — Surrogate Endpoint (SUR): Blood pressure
Study 22556176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9856958 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9856958 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8568984 — Surrogate Endpoint (SUR): Blood pressure
Study 8568984 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26201190 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 21502544 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19304671 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 16963472 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12536700 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12536700 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 20227891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8853725 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26501411 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 15516697 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15516697 — Surrogate Endpoint (SUR): Blood pressure
Study 26276754 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26276754 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 14975482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3129596 — Predictive Biomarker (PRD): INA mRNA
Genes: INA; NEF5
Study 3129596 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26762075 — Surrogate Endpoint (SUR): Blood pressure
Study 23606168 — Predictive Biomarker (PRD): BCL11A mRNA
Genes: BCL11A; CTIP1; EVI9; KIAA1809; ZNF856
Study 23606168 — Predictive Biomarker (PRD): MYB mRNA
Genes: MYB
Study 23606168 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 17006323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17006323 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17006323 — Surrogate Endpoint (SUR): Serum creatinine
Study 12571666 — Safety Biomarker (SAF): MTHFR
Study 31687165 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 27253174 — Surrogate Endpoint (SUR): Serum creatinine
Study 27253174 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28531113 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 25965717 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 10722029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25056532 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15249568 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15249568 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3017174 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30868938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19095827 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 12411457 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12411457 — Surrogate Endpoint (SUR): Blood pressure
Study 9857348 — Monitoring Biomarker (MOI): HBV DNA
Study 8580556 — Surrogate Endpoint (SUR): Blood pressure
Study 26092545 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 26092545 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 11417848 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 11417848 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 11417848 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7918140 — Surrogate Endpoint (SUR): Blood pressure
Study 30535188 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30535188 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 30535188 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 30535188 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24651682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24651682 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12039991 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12039991 — Surrogate Endpoint (SUR): Serum creatinine
Study 10526897 — Surrogate Endpoint (SUR): Blood pressure
Study 10526897 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25691622 — Surrogate Endpoint (SUR): Blood pressure
Study 17192828 — Surrogate Endpoint (SUR): Serum creatinine
Study 16878328 — Predictive Biomarker (PRD): ATF1 mRNA
Genes: ATF1
Study 10813588 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31698177 — Predictive Biomarker (PRD): Anti-acetylcholine receptor antibody
Study 28482746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FBXO32 mRNA
Genes: FBXO32
Study 18824331 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 3540223 — Surrogate Endpoint (SUR): Blood pressure
Study 30109784 — Surrogate Endpoint (SUR): Serum potassium
Study 30109784 — Surrogate Endpoint (SUR): Blood pressure
Study 18579440 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30412077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30412077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30412077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26714803 — Surrogate Endpoint (SUR): Blood pressure
Study 24460799 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15848920 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 12153804 — Predictive Biomarker (PRD): ETV5 mRNA
Genes: ETV5; ERM
Study 8551652 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2285464 — Surrogate Endpoint (SUR): Serum potassium
Study 21860559 — Safety Biomarker (SAF): Reactive oxygen species
Study 10803439 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6220603 — Surrogate Endpoint (SUR): Serum creatinine
Study 30448455 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26375919 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26375919 — Safety Biomarker (SAF): BDNF
Study 23208878 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16413241 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16413241 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8232678 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28578704 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 2189617 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2189617 — Surrogate Endpoint (SUR): Blood pressure
Study 26016823 — Surrogate Endpoint (SUR): Blood pressure
Study 17183729 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 10750576 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10750576 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10750576 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15855347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30272245 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 31274231 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 31274231 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25282519 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22254067 — Surrogate Endpoint (SUR): Bone mineral density
Study 16372516 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7510510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7510510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2660519 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24146327 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24146327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20920765 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 17015817 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 7885501 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31343543 — Surrogate Endpoint (SUR): Blood pressure
Study 19318435 — Surrogate Endpoint (SUR): Blood pressure
Study 16478779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16478779 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3286039 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18154801 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18154801 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18154801 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 18154801 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 11549104 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 8150098 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22449658 — Surrogate Endpoint (SUR): Serum creatinine
Study 21606430 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 9253574 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 9253574 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29522355 — Surrogate Endpoint (SUR): Blood pressure
Study 27980499 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25319951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25319951 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25319951 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 25319951 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 22246217 — Surrogate Endpoint (SUR): Bone mineral density
Study 31978826 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 22849770 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22849770 — Surrogate Endpoint (SUR): Blood pressure
Study 1534287 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26232049 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26232049 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 26232049 — Safety Biomarker (SAF): Reactive oxygen species
Study 18940393 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18940393 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10831173 — Surrogate Endpoint (SUR): Plasma ammonia
Study 7679615 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7679615 — Surrogate Endpoint (SUR): Blood pressure
Study 7679615 — Surrogate Endpoint (SUR): Serum potassium
Study 2425159 — Surrogate Endpoint (SUR): Blood pressure
Study 23174399 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 22025377 — Surrogate Endpoint (SUR): Blood pressure
Study 10739742 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24589084 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 11994554 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 25700386 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17678657 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 11956353 — Surrogate Endpoint (SUR): Blood pressure
Study 8028511 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 241366 — Surrogate Endpoint (SUR): Blood pressure
Study 20947493 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 17309447 — Surrogate Endpoint (SUR): Blood pressure
Study 2569194 — Surrogate Endpoint (SUR): Blood pressure
Study 30721655 — Surrogate Endpoint (SUR): Blood pressure
Study 9174136 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 25472825 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23433852 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23433852 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17301824 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 17301824 — Surrogate Endpoint (SUR): Blood pressure
Study 9932142 — Surrogate Endpoint (SUR): Bone mineral density
Study 8050541 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30659070 — Surrogate Endpoint (SUR): Blood pressure
Study 25666215 — Surrogate Endpoint (SUR): Blood pressure
Study 21311168 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 19338158 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19338158 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 16412750 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16412750 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16412750 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 12587182 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 12587182 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9577356 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30355512 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 11905959 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29164399 — Safety Biomarker (SAF): Hyaluronic acid
Study 24692284 — Surrogate Endpoint (SUR): Blood pressure
Study 22687601 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12784171 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10561205 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31022110 — Surrogate Endpoint (SUR): Blood pressure
Study 22336878 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17589194 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12544376 — Surrogate Endpoint (SUR): Blood pressure
Study 8847874 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2941372 — Surrogate Endpoint (SUR): Blood pressure
Study 25643617 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 19584736 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 26920896 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26920896 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26920896 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26920896 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 22413021 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 22413021 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22413021 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 22413021 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18980783 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 12611908 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 30939189 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25147806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17953679 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24598306 — Surrogate Endpoint (SUR): Serum creatinine
Study 17150108 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 27228435 — Surrogate Endpoint (SUR): Blood pressure
Study 24687165 — Surrogate Endpoint (SUR): Blood pressure
Study 7780069 — Surrogate Endpoint (SUR): Blood pressure
Study 2109023 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2109023 — Safety Biomarker (SAF): Interleukin 1
Study 2109023 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 14979213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9220179 — Surrogate Endpoint (SUR): Serum creatinine
Study 3329738 — Surrogate Endpoint (SUR): Serum testosterone
Study 29570588 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 22672501 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22672501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2