TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28526870 — Safety Biomarker (SAF): miR-133a
Study 28526870 — Safety Biomarker (SAF): miR-133b
Genes: MIR133B
Study 28526870 — Safety Biomarker (SAF): miR-206
Genes: MIR206
Study 28526870 — Safety Biomarker (SAF): miR-181a
Study 28526870 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 28526870 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12110777 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9449397 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9449397 — Surrogate Endpoint (SUR): Blood pressure
Study 22947356 — Surrogate Endpoint (SUR): Blood pressure
Study 22947356 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12135935 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7072313 — Surrogate Endpoint (SUR): Blood pressure
Study 30567753 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 30567753 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 22747705 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 17062840 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 16263089 — Predictive Biomarker (PRD): TP53INP2 mRNA
Genes: TP53INP2; C20orf110; DOR; PINH
Study 11867377 — Surrogate Endpoint (SUR): Blood pressure
Study 1533186 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26636096 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 18326962 — Surrogate Endpoint (SUR): Blood pressure
Study 12657225 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 12657225 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 12657225 — Surrogate Endpoint (SUR): Blood pressure
Study 12657225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12657225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9475305 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2455115 — Surrogate Endpoint (SUR): Blood pressure
Study 18773749 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18773749 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8008680 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23814044 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19249413 — Surrogate Endpoint (SUR): Blood pressure
Study 15090706 — Surrogate Endpoint (SUR): Blood pressure
Study 8193351 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2555187 — Surrogate Endpoint (SUR): Blood pressure
Study 27813398 — Surrogate Endpoint (SUR): Bone mineral density
Study 17481705 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17481705 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17481705 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9678787 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 9678787 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9678787 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2566637 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 12875806 — Surrogate Endpoint (SUR): Blood pressure
Study 17703315 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 17703315 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 17703315 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7634883 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7634883 — Surrogate Endpoint (SUR): Blood pressure
Study 21237212 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 21237212 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15784036 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1779513 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 1779513 — Surrogate Endpoint (SUR): Blood pressure
Study 21793389 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 8033496 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 8033496 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28011037 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 12753318 — Surrogate Endpoint (SUR): Bone mineral density
Study 10618584 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11565519 — Surrogate Endpoint (SUR): Blood pressure
Study 3034018 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3034018 — Surrogate Endpoint (SUR): Blood pressure
Study 10233186 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29555790 — Surrogate Endpoint (SUR): Blood pressure
Study 19663893 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 14574348 — Surrogate Endpoint (SUR): Blood pressure
Study 14574348 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14574348 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22685122 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 22646630 — Surrogate Endpoint (SUR): Pathological complete response
Study 16135900 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31272931 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28097266 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 25340318 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16946093 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16946093 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 16946093 — Predictive Biomarker (PRD): LY96
Genes: MD-2
Study 27121444 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 27121444 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27121444 — Surrogate Endpoint (SUR): Blood pressure
Study 20235838 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31986357 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31986357 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26150412 — Predictive Biomarker (PRD): SCAMP1 mRNA
Genes: SCAMP1; SCAMP
Study 19651163 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22054688 — Surrogate Endpoint (SUR): Blood pressure
Study 16230866 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10228112 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 10228112 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 20197785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2222979 — Surrogate Endpoint (SUR): Blood pressure
Study 26688235 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23421759 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23421759 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23421759 — Surrogate Endpoint (SUR): Blood pressure
Study 21915478 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 19506099 — Surrogate Endpoint (SUR): Blood pressure
Study 19506099 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16834970 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16834970 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10445673 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15848575 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 11882931 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 10531077 — Surrogate Endpoint (SUR): Bone mineral density
Study 7789045 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7789045 — Surrogate Endpoint (SUR): Serum potassium
Study 30327952 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 29211893 — Surrogate Endpoint (SUR): Blood pressure
Study 26918556 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 7549411 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7549411 — Surrogate Endpoint (SUR): Blood pressure
Study 31020351 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 22641777 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10490438 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 16817038 — Surrogate Endpoint (SUR): Blood pressure
Study 12614804 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28453453 — Surrogate Endpoint (SUR): Bone mineral density
Study 24905629 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 24905629 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22301417 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19952998 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12218740 — Surrogate Endpoint (SUR): Blood pressure
Study 12218740 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21378155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21378155 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21378155 — Surrogate Endpoint (SUR): Blood pressure
Study 21378155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29453687 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29453687 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 18268065 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 18268065 — Surrogate Endpoint (SUR): Blood pressure
Study 18268065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18268065 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12460699 — Surrogate Endpoint (SUR): Blood pressure
Study 12460699 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10554808 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 10554808 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10554808 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 31780869 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31780869 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 25083802 — Surrogate Endpoint (SUR): Blood pressure
Study 12239432 — Safety Biomarker (SAF): Reactive oxygen species
Study 31204078 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 31204078 — Predictive Biomarker (PRD): Microsatellite instability
Study 31204078 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study 19789415 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19789415 — Surrogate Endpoint (SUR): Blood pressure
Study 17257820 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11744606 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 7990700 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28679486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28679486 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28679486 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25727857 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 19484786 — Surrogate Endpoint (SUR): Bone mineral density
Study 10410299 — Surrogate Endpoint (SUR): Blood pressure
Study 31533751 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31533751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31533751 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19753300 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17319412 — Surrogate Endpoint (SUR): Blood pressure
Study 8006914 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8006914 — Surrogate Endpoint (SUR): Serum potassium
Study 19516176 — Surrogate Endpoint (SUR): Blood pressure
Study 3207855 — Surrogate Endpoint (SUR): Blood pressure
Study 15752879 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11930309 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11930309 — Safety Biomarker (SAF): Preexisting antibody
Study 31579987 — Safety Biomarker (SAF): Hyaluronic acid
Study 29314176 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19737527 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8829023 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21600325 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 21600325 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29911909 — Predictive Biomarker (PRD): IMPA1 mRNA
Genes: IMPA1; IMPA
Study 19682803 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19682803 — Safety Biomarker (SAF): BDNF
Study 9376574 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 9376574 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11886505 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24607773 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 24607773 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17299116 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 17299116 — Surrogate Endpoint (SUR): Blood pressure
Study 17472017 — Surrogate Endpoint (SUR): Blood pressure
Study 2836565 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18053632 — Surrogate Endpoint (SUR): Blood pressure
Study 12830671 — Surrogate Endpoint (SUR): Blood pressure
Study 17418038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15229622 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15229622 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15229622 — Surrogate Endpoint (SUR): Blood pressure
Study 10431997 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 10431997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10431997 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 6499724 — Surrogate Endpoint (SUR): Blood pressure
Study 29949174 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29949174 — Surrogate Endpoint (SUR): Blood pressure
Study 15202583 — Surrogate Endpoint (SUR): Bone mineral density
Study 15202583 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17697915 — Surrogate Endpoint (SUR): Blood pressure
Study 16141420 — Surrogate Endpoint (SUR): Blood pressure
Study 9772936 — Surrogate Endpoint (SUR): Blood pressure
Study 9772936 — Surrogate Endpoint (SUR): Serum potassium
Study 7531877 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7531877 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17594856 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17594856 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29511807 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 26370220 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20073227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15269070 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 3078426 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27018313 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23956183 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 21713704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2067362 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 2067362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29030065 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23785427 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11672580 — Surrogate Endpoint (SUR): Blood pressure
Study 26329656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26329656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26686682 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26686682 — Surrogate Endpoint (SUR): Blood pressure
Study 24317556 — Surrogate Endpoint (SUR): Blood pressure
Study 24317556 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24317556 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18602824 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11195715 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27259714 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7230728 — Surrogate Endpoint (SUR): Blood pressure
Study 30411377 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10601178 — Surrogate Endpoint (SUR): Serum testosterone
Study 8554931 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 28251402 — Surrogate Endpoint (SUR): Blood pressure
Study 18240879 — Monitoring Biomarker (MOI): HBV DNA
Study 16531896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16531896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10411250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10411250 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10411250 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6990861 — Surrogate Endpoint (SUR): Serum creatinine
Study 22763465 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22763465 — Predictive Biomarker (PRD): Hormone receptor
Study 22763465 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22763465 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22790267 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 19446151 — Surrogate Endpoint (SUR): Blood pressure
Study 15042010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 12958723 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12958723 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1990794 — Surrogate Endpoint (SUR): Blood pressure
Study 31267524 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31267524 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28850021 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 20303788 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 14730323 — Surrogate Endpoint (SUR): Blood pressure
Study 25738345 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 22571552 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 22571552 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22571552 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22571552 — Surrogate Endpoint (SUR): Blood pressure
Study 18175550 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11533570 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11533570 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28125158 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22046961 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11152850 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9539282 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8088918 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8088918 — Surrogate Endpoint (SUR): Blood pressure
Study 25982297 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25982297 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25982297 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27122490 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 27122490 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27122490 — Predictive Biomarker (PRD): PGR mRNA
Genes: PGR; NR3C3
Study 27122490 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 27122490 — Predictive Biomarker (PRD): ACTA2 mRNA
Genes: ACTA2; ACTSA; ACTVS; GIG46
Study 10835439 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 10835439 — Surrogate Endpoint (SUR): Blood pressure
Study 8225149 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8225149 — Surrogate Endpoint (SUR): Blood pressure
Study 25509236 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25509236 — Surrogate Endpoint (SUR): Blood pressure
Study 12812866 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 12812866 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10827410 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG