TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15834703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15834703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9822137 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9822137 — Surrogate Endpoint (SUR): Blood pressure
Study 25505238 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18807247 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18807247 — Safety Biomarker (SAF): BDNF
Study 6996121 — Surrogate Endpoint (SUR): Serum testosterone
Study 22040532 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17508621 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16285996 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16285996 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17149760 — Surrogate Endpoint (SUR): Pathological complete response
Study 15894479 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15894479 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15894479 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7999488 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2904310 — Surrogate Endpoint (SUR): Blood pressure
Study 18358927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18358927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10916812 — Surrogate Endpoint (SUR): Bone mineral density
Study 23620937 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 9095079 — Surrogate Endpoint (SUR): Blood pressure
Study 9095079 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3780818 — Surrogate Endpoint (SUR): Blood pressure
Study 20693886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20693886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20693886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20693886 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20693886 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20693886 — Safety Biomarker (SAF): Interleukin 1
Study 18842789 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16076683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16076683 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 1555623 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31486700 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31486700 — Surrogate Endpoint (SUR): Blood pressure
Study 31486700 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31486700 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31486700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31486700 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27016644 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 18573392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18573392 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18573392 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 18573392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7582326 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 22771129 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8106759 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 28733656 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 23032085 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30165429 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 30165429 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 25286702 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 23072093 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 23072093 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23072093 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8777468 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 30669763 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 26444729 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 26444729 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15049885 — Surrogate Endpoint (SUR): Bone mineral density
Study 12515414 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21870630 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26987376 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24887013 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24887013 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22346753 — Predictive Biomarker (PRD): ALDH1A2 mRNA
Genes: ALDH1A2; RALDH2
Study 17898702 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 31648988 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 15293891 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28475816 — Safety Biomarker (SAF): Interleukin 1
Study 9303380 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25871479 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25130629 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27631634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27631634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30099602 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17333244 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11185023 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 9008662 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 9008662 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30409776 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 30409776 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21859750 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21859750 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19758618 — Surrogate Endpoint (SUR): Bone mineral density
Study 26963423 — Surrogate Endpoint (SUR): Blood pressure
Study 23602059 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19652968 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12027469 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10845393 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 7009310 — Monitoring Biomarker (MOI): HBV DNA
Study 30641678 — Surrogate Endpoint (SUR): Blood pressure
Study 16845641 — Surrogate Endpoint (SUR): Blood pressure
Study 15616893 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 15616893 — Surrogate Endpoint (SUR): Bone mineral density
Study 12777950 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8723170 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8723170 — Surrogate Endpoint (SUR): Blood pressure
Study 3892993 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26181014 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29045207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21899843 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31916648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31916648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30173153 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 30173153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25394429 — Surrogate Endpoint (SUR): Serum creatinine
Study 30964381 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 27135478 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2673620 — Surrogate Endpoint (SUR): Blood pressure
Study 23186950 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 23186950 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8986931 — Surrogate Endpoint (SUR): Blood pressure
Study 27798397 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 25359150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25359150 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 25359150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18614424 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 18614424 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 11918715 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11918715 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11918715 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8621019 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21512162 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21512162 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21512162 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15208492 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 8448744 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20509997 — Monitoring Biomarker (MOI): HBV DNA
Study 24261229 — Surrogate Endpoint (SUR): Blood pressure
Study 27716478 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24781960 — Surrogate Endpoint (SUR): Blood pressure
Study 24781960 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1850142 — Surrogate Endpoint (SUR): Blood pressure
Study 26138472 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 26138472 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 5343357 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 16467234 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16467234 — Surrogate Endpoint (SUR): Blood pressure
Study 16467234 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29196825 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26889737 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 20176771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29025227 — Safety Biomarker (SAF): Hyaluronic acid
Study 17224217 — Monitoring Biomarker (MOI): HBV DNA
Study 31119846 — Surrogate Endpoint (SUR): Serum creatinine
Study 15983390 — Surrogate Endpoint (SUR): Bone mineral density
Study 15983390 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31074161 — Safety Biomarker (SAF): Hyaluronic acid
Study 22003058 — Surrogate Endpoint (SUR): Blood pressure
Study 19665606 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11895913 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7719395 — Surrogate Endpoint (SUR): Blood pressure
Study 31653513 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30152298 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 25698197 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25698197 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25698197 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 21896879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11839457 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9737646 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27669730 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27669730 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27669730 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 27669730 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 27669730 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 24070164 — Predictive Biomarker (PRD): BTC mRNA
Genes: BTC
Study 8751016 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8751016 — Surrogate Endpoint (SUR): Blood pressure
Study 23244709 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 17950038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3534333 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3534333 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3285877 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20665468 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 17663307 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15313942 — Surrogate Endpoint (SUR): Serum sodium
Study 24295879 — Surrogate Endpoint (SUR): Blood pressure
Study 9706373 — Surrogate Endpoint (SUR): Blood pressure
Study 12621274 — Surrogate Endpoint (SUR): Blood pressure
Study 9174835 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 3980239 — Surrogate Endpoint (SUR): Blood pressure
Study 28834086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28834086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28834086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27958622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27958622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25219200 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17261244 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11517136 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2906118 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 794661 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20108073 — Surrogate Endpoint (SUR): Blood pressure
Study 20108073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20108073 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20108073 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7880945 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 26032843 — Surrogate Endpoint (SUR): Blood pressure
Study 15685822 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16309749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 1532127 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23342969 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14969403 — Surrogate Endpoint (SUR): Bone mineral density
Study 22190678 — Predictive Biomarker (PRD): NDUFB6 mRNA
Genes: NDUFB6
Study 20459820 — Surrogate Endpoint (SUR): Blood pressure
Study 12022597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12022597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8275793 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 31888740 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 29100193 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 1339054 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30577864 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16042029 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 12079501 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 6799913 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 17145226 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31092727 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 29400576 — Surrogate Endpoint (SUR): Blood pressure
Study 28078860 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15389228 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 28098099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28098099 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28098099 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19828711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16760795 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16760795 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12386642 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7576325 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19124628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26002493 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16839845 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16839845 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16839845 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9310126 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9310126 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25182161 — Surrogate Endpoint (SUR): Blood pressure
Study 12744488 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12744488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12744488 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25495490 — Predictive Biomarker (PRD): Hormone receptor
Study 19379098 — Surrogate Endpoint (SUR): Bacterial count
Study 16489082 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16489082 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31676953 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21490326 — Surrogate Endpoint (SUR): Blood pressure
Study 21490326 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26762524 — Surrogate Endpoint (SUR): Blood pressure
Study 26762524 — Surrogate Endpoint (SUR): Serum creatinine
Study 11347747 — Surrogate Endpoint (SUR): Blood pressure
Study 7951238 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 22424458 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28134225 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 20939799 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15533493 — Surrogate Endpoint (SUR): Blood pressure
Study 14740593 — Surrogate Endpoint (SUR): Blood pressure
Study 18451229 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18451229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18451229 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10553182 — Surrogate Endpoint (SUR): Blood pressure
Study 25140396 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17974149 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 17974149 — Surrogate Endpoint (SUR): Serum creatinine
Study 31564529 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 26376093 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 23650408 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23868287 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 24415868 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23111478 — Surrogate Endpoint (SUR): Blood pressure
Study 24224448 — Surrogate Endpoint (SUR): Blood pressure