TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01853787 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01853787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01853787 — Safety Biomarker (SAF): Interleukin 1
Study NCT01853787 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study NCT01853787 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01853787 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02944032 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00789425 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00581802 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02599714 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02564237 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT02323867 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01999179 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT03789474 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01826877 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT02028507 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02028507 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02028507 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00525473 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study NCT00525473 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study NCT03752983 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study NCT00280267 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00002554 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT00628823 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study NCT02032225 — Predictive Biomarker (PRD): NOTCH3 mRNA
Genes: NOTCH3
Study NCT01224132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01224132 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT01132430 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00653783 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT02352974 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03887182 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study NCT03407196 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00171405 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04263220 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03499626 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT03499626 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03499626 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03499626 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study NCT03093441 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03437538 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT04571814 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study NCT00252915 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01204580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03159156 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02206659 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01910857 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04176497 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03052491 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01835678 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02383511 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00442234 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00934089 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00799383 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03552731 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03677921 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04682041 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04682041 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04682041 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00265759 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02602314 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02602314 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04511559 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03649893 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02235025 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02576002 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00004067 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00320788 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00959283 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study NCT00347542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00347542 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02386735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04326777 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01443065 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01443065 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00189982 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT04324255 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04324255 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT04324255 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT04185311 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04185311 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03066830 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00003805 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02070744 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04101149 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT04121026 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04314349 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04549636 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04568044 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03857893 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT04944251 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT00204230 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00925249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04447651 — Predictive Biomarker (PRD): U2AF1 mRNA
Genes: U2AF1; U2AF35; U2AFBP; FP793
Study NCT02098967 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT03048734 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01249664 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03131908 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03131908 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02509273 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00791570 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00791570 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00791570 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT03187275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01423201 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT04069715 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02197247 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02197247 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02197247 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01819298 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT05946148 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02476526 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00962676 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01940601 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT01202812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05517915 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04425512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02191683 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02191683 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00633750 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00633750 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01471678 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00105417 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03773263 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study NCT02728596 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02728596 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04036019 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04036019 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01018563 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT02210767 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03482544 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03320174 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT00844129 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00626223 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02258464 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02258464 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02258464 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03082781 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03082781 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00932646 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT05206578 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study NCT01096381 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00636558 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study NCT03765632 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03765632 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT03765632 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT03128411 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02030184 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study NCT00384566 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03717259 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03179657 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03179657 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01969357 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02499822 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04499339 — Predictive Biomarker (PRD): SLAMF7 mRNA
Genes: SLAMF7; CS1; UNQ576/PRO1138
Study NCT02738593 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02738593 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00237094 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001872 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02578511 — Predictive Biomarker (PRD): POMP mRNA
Genes: POMP; C13orf12; UMP1; HSPC014; HSPC036; PNAS-110
Study NCT04217720 — Predictive Biomarker (PRD): ASPH mRNA
Genes: ASPH; BAH
Study NCT03575013 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03164135 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT03164135 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04769804 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT02379156 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04755543 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01275885 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03663998 — Safety Biomarker (SAF): Interleukin 12
Study NCT01794117 — Safety Biomarker (SAF): Interleukin 1
Study NCT01795794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02959723 — Predictive Biomarker (PRD): BMPR2 mRNA
Genes: BMPR2; PPH1
Study NCT04888468 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00008203 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00008203 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00402415 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03130257 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03148132 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03148132 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00899574 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT02733432 — Predictive Biomarker (PRD): CD101 mRNA
Genes: CD101; EWI101; IGSF2; V7
Study NCT04380896 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00195715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03673852 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01921387 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT01018706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT01151007 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02155985 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01096082 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study NCT01096082 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01124669 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01124669 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03113110 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03113110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01625026 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT04726800 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00172757 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT00172757 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00172757 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01744925 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01744925 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03027687 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study NCT02019693 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02019693 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02019693 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT02019693 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03758066 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01734187 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01734187 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01734187 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02338076 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00237549 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04530916 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00678509 — Predictive Biomarker (PRD): TTK mRNA
Genes: TTK; MPS1; MPS1L1
Study NCT00678509 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT04876378 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02739594 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00786890 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00514046 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT00514046 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04407221 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01456481 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03225846 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT02369042 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02908360 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00796822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06611904 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01878370 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00638599 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00148915 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01302756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03675477 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT03675477 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study NCT00249756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study NCT02855164 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT03135704 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT00238810 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00493025 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04454294 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001849 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00005378 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01695109 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03416192 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT03416192 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT01461733 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00342056 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study NCT04114695 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04071600 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT01462214 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01462214 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT03084939 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04282590 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT04367662 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01234766 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT03918954 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01613261 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT00634907 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00634907 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT02192736 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00269048 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT03095612 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02984111 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study NCT00405171 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00330512 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02187497 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03154723 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03154723 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01248234 — Surrogate Endpoint (SUR): Blood pressure