TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17984108 — Surrogate Endpoint (SUR): Blood pressure
Study 12542609 — Monitoring Biomarker (MOI): HBV DNA
Study 25038314 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25038314 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 22422386 — Surrogate Endpoint (SUR): Blood pressure
Study 21146749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 17605023 — Surrogate Endpoint (SUR): Bone mineral density
Study 11522879 — Surrogate Endpoint (SUR): Serum creatinine
Study 11522879 — Surrogate Endpoint (SUR): Serum sodium
Study 9565804 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 10917002 — Surrogate Endpoint (SUR): Bone mineral density
Study 10917002 — Surrogate Endpoint (SUR): Serum calcium
Study 30819098 — Surrogate Endpoint (SUR): Blood pressure
Study 29931092 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24125844 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 24125844 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24125844 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 8141692 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31889148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29275580 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29275580 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23274145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28446644 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 2426514 — Surrogate Endpoint (SUR): Blood pressure
Study 28513852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26701110 — Surrogate Endpoint (SUR): Blood pressure
Study 9065248 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27977472 — Surrogate Endpoint (SUR): Blood pressure
Study 20651608 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11162695 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 12164876 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9205027 — Surrogate Endpoint (SUR): Blood pressure
Study 11989838 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 10521743 — Surrogate Endpoint (SUR): Blood pressure
Study 20574649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15883634 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 12379164 — Surrogate Endpoint (SUR): Blood pressure
Study 31821750 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 31196032 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25719991 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12780746 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9354348 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9354348 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 9354348 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 8222508 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8222508 — Surrogate Endpoint (SUR): Blood pressure
Study 8222508 — Surrogate Endpoint (SUR): Serum potassium
Study 27858150 — Surrogate Endpoint (SUR): Blood pressure
Study 15811048 — Surrogate Endpoint (SUR): Bacterial count
Study 1714950 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 28423301 — Safety Biomarker (SAF): Interleukin 12
Study 21114607 — Surrogate Endpoint (SUR): Blood pressure
Study 14970135 — Surrogate Endpoint (SUR): Blood pressure
Study 16848777 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 11422727 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 15811704 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 31037288 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28158243 — Surrogate Endpoint (SUR): Blood pressure
Study 23681294 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 11742271 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11742271 — Surrogate Endpoint (SUR): Serum potassium
Study 26137702 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18242128 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18242128 — Surrogate Endpoint (SUR): Serum creatinine
Study 12708605 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1731547 — Surrogate Endpoint (SUR): Blood pressure
Study 9278828 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27982198 — Surrogate Endpoint (SUR): Blood pressure
Study 12796760 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24591201 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 1815225 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 27025186 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24696091 — Predictive Biomarker (PRD): ENTPD1 mRNA
Genes: ENTPD1; CD39
Study 24696091 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 24696091 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27295811 — Surrogate Endpoint (SUR): Blood pressure
Study 27295811 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17498388 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 9717676 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 905483 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9130130 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 7910028 — Surrogate Endpoint (SUR): Blood pressure
Study 22695506 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22695506 — Surrogate Endpoint (SUR): Blood pressure
Study 31564585 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 21333698 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17602156 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17602156 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17602156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31868699 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 28179351 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 23783025 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23795576 — Surrogate Endpoint (SUR): Blood pressure
Study 6306711 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30608440 — Monitoring Biomarker (MOI): HBV DNA
Study 7654944 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 23040887 — Predictive Biomarker (PRD): FIP1L1 mRNA
Genes: FIP1L1; FIP1; RHE
Study 23040887 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 11423497 — Surrogate Endpoint (SUR): Blood pressure
Study 8388332 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 8388332 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8388332 — Surrogate Endpoint (SUR): Blood pressure
Study 3812308 — Surrogate Endpoint (SUR): Blood pressure
Study 30641827 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23780458 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8768852 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1993796 — Surrogate Endpoint (SUR): Blood pressure
Study 16467018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26633806 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26633806 — Surrogate Endpoint (SUR): Pathological complete response
Study 21377179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21377179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21377179 — Surrogate Endpoint (SUR): Blood pressure
Study 10761802 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2671502 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20606150 — Surrogate Endpoint (SUR): Blood pressure
Study 20606150 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29528692 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 26797700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17923463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17923463 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12127609 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7552926 — Surrogate Endpoint (SUR): Blood pressure
Study 31461355 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 26467096 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11137102 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11137102 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9853084 — Surrogate Endpoint (SUR): Bone mineral density
Study 8061852 — Surrogate Endpoint (SUR): Blood pressure
Study 3243924 — Surrogate Endpoint (SUR): Blood pressure
Study 27022799 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18809622 — Surrogate Endpoint (SUR): Blood pressure
Study 12892455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10230189 — Surrogate Endpoint (SUR): Blood pressure
Study 1991366 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 29687335 — Safety Biomarker (SAF): Hyaluronic acid
Study 22278094 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 15060773 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 9696456 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 7656919 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15041394 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 30242918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27873502 — Surrogate Endpoint (SUR): Blood pressure
Study 27873502 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16952155 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9416883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18787222 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 15116008 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15116008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15116008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15116008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27714002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16376202 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 12555509 — Surrogate Endpoint (SUR): Blood pressure
Study 9430987 — Surrogate Endpoint (SUR): Serum calcium
Study 9430987 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 9430987 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 8007703 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 18419948 — Surrogate Endpoint (SUR): Blood pressure
Study 9506266 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8352874 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 12871780 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10329064 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1929608 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1929608 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1929608 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6753893 — Surrogate Endpoint (SUR): Blood pressure
Study 30093398 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 30093398 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 28378369 — Predictive Biomarker (PRD): REEP5 mRNA
Genes: REEP5; C5orf18; DP1; TB2
Study 17720383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17720383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17720383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3291150 — Surrogate Endpoint (SUR): Blood pressure
Study 25681277 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 10784627 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 10784627 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 10784627 — Surrogate Endpoint (SUR): Serum creatinine
Study 16583964 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29708829 — Surrogate Endpoint (SUR): Serum testosterone
Study 24530176 — Surrogate Endpoint (SUR): Blood pressure
Study 20591807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20591807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20591807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16618841 — Surrogate Endpoint (SUR): Blood pressure
Study 17999333 — Surrogate Endpoint (SUR): Serum creatinine
Study 17999333 — Surrogate Endpoint (SUR): Serum uric acid
Study 17999333 — Surrogate Endpoint (SUR): Serum calcium
Study 7887118 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 7887118 — Predictive Biomarker (PRD): ANTXR1 mRNA
Genes: ANTXR1; ATR; TEM8
Study 31506292 — Predictive Biomarker (PRD): MAP3K5 mRNA
Genes: MAP3K5; ASK1; MAPKKK5; MEKK5
Study 16235834 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1977371 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 28244495 — Safety Biomarker (SAF): Sodium/hydrogen exchanger 3
Genes: SLC9A3; NHE3
Study 21871113 — Surrogate Endpoint (SUR): Blood pressure
Study 19720797 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7817832 — Surrogate Endpoint (SUR): Bone mineral density
Study 14985565 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 14755377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14755377 — Safety Biomarker (SAF): IL16
Genes: LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
Study 19843490 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 31498885 — Predictive Biomarker (PRD): CTPS1 mRNA
Genes: CTPS1; CTPS
Study 28528342 — Safety Biomarker (SAF): Hyaluronic acid
Study 23220477 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23220477 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 23220477 — Safety Biomarker (SAF): IL-6 and IL-10
Study 25090744 — Surrogate Endpoint (SUR): Blood pressure
Study 11289484 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 11289484 — Surrogate Endpoint (SUR): Blood pressure
Study 9398709 — Surrogate Endpoint (SUR): Blood pressure
Study 9398709 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24957485 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 15073842 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11842947 — Predictive Biomarker (PRD): MRAS mRNA
Genes: MRAS; RRAS3
Study 11842947 — Surrogate Endpoint (SUR): Serum creatinine
Study 8094308 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30139501 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24250451 — Surrogate Endpoint (SUR): Blood pressure
Study 18398809 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 18398809 — Surrogate Endpoint (SUR): Blood pressure
Study 18398809 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30301241 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2580156 — Surrogate Endpoint (SUR): Blood pressure
Study 16042796 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 16042796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10081632 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7574046 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7574046 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27628045 — Surrogate Endpoint (SUR): Bone mineral density
Study 19264972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15154938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15154938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18668535 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 18668535 — Safety Biomarker (SAF): Interleukin 1
Study 18668535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26115560 — Surrogate Endpoint (SUR): Blood pressure
Study 26115560 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26115560 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26115560 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15505128 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15505128 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9924223 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 22776014 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20057364 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15867184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15867184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30899947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30899947 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20354448 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 20354448 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 20354448 — Predictive Biomarker (PRD): ADGRE5 mRNA
Genes: ADGRE5; CD97
Study 20354448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20354448 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17452762 — Surrogate Endpoint (SUR): Bone mineral density
Study 15494721 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 31356678 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31356678 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 31451521 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 31198076 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 21386036 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21386036 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21386036 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18535196 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9074572 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9074572 — Surrogate Endpoint (SUR): Serum creatinine
Study 3532694 — Surrogate Endpoint (SUR): Blood pressure
Study 16378639 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23436922 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 23436922 — Surrogate Endpoint (SUR): Bone mineral density
Study 16381626 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7555502 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 6158861 — Surrogate Endpoint (SUR): Blood pressure
Study 9412655 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3690230 — Surrogate Endpoint (SUR): Blood pressure
Study 26121878 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26121878 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12534148 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 6120346 — Surrogate Endpoint (SUR): Blood pressure
Study 31957521 — Surrogate Endpoint (SUR): Blood pressure
Study 26219281 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 11350400 — Predictive Biomarker (PRD): P2RX1 mRNA
Genes: P2RX1; P2X1
Study 11350400 — Predictive Biomarker (PRD): P2RX2 mRNA
Genes: P2RX2; P2X2
Study 11350400 — Predictive Biomarker (PRD): P2RX5 mRNA
Genes: P2RX5; P2X5