TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00543413 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02751840 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01675154 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT00970099 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00280761 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02061865 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02308683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03931369 — Surrogate Endpoint (SUR): Serum sodium
Study NCT04652219 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT04652219 — Predictive Biomarker (PRD): GUCY2C mRNA
Genes: GUCY2C; GUC2C; STAR
Study NCT04543006 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00976404 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02751008 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01255436 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00711191 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study NCT01211678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02803580 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00705952 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01594788 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03544762 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03544762 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT00916292 — Safety Biomarker (SAF): Fibroblast growth factor 1
Genes: FGF1
Study NCT03155620 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT00503451 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02740049 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT02740049 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT02740049 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study NCT00654862 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02670135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02670135 — Safety Biomarker (SAF): Interleukin 1
Study NCT02386150 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02342236 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT02342236 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT01344668 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00853164 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT00853164 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02366650 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02366650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04038996 — Safety Biomarker (SAF): miR-146a
Genes: MIR146A
Study NCT02296047 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02686658 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT02686658 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01387555 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02553512 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01633554 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study NCT00546052 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04502238 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04078659 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00779389 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00995501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04693962 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01877083 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT04127487 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04127487 — Predictive Biomarker (PRD): CARD8 mRNA
Genes: CARD8; DACAR; KIAA0955; NDPP1
Study NCT01238718 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00745511 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02488122 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02445898 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04479488 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03989037 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06309459 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT00399321 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03389321 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02669888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03849508 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03278132 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02999672 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02999672 — Predictive Biomarker (PRD): UBC mRNA
Genes: UBC
Study NCT03909971 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03047096 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03471663 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03163914 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02633709 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT02542319 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03269149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT03269149 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03269149 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT03269149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03269149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01313494 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00157976 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04201834 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT01256398 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01256398 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00351078 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02526875 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02467270 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02467270 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02842125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02281214 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02281214 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00795483 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04296838 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02177760 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04380012 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04249986 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03032172 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT03861871 — Predictive Biomarker (PRD): Cyclin-dependent kinase-like 5
Genes: CDKL5; STK9
Study NCT01538004 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02891135 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT06299631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00155155 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03888092 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03888092 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02532023 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01324232 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT05325905 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT00957008 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00573300 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT05373147 — Predictive Biomarker (PRD): MSLN mRNA
Genes: MSLN; MPF
Study NCT00423384 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01445028 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT03758989 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT03758989 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT04036773 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00004276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01740648 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01740648 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT05101603 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04993378 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT02268747 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02268747 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02268747 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT04690660 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04120454 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04120454 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01901861 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01901861 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00005005 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03013764 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT03013764 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04404595 — Predictive Biomarker (PRD): CLDN18 mRNA
Genes: CLDN18; UNQ778/PRO1572
Study NCT03144895 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02437539 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study NCT03527823 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03785067 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01240460 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00369356 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT02104492 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT03220152 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02962050 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02007174 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02007174 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01677819 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03516760 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT00932451 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03527563 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01290770 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study NCT01290770 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01712893 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04438863 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03477994 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01479192 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT04245085 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02190773 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT02190773 — Safety Biomarker (SAF): Interleukin 1
Study NCT04743947 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03602079 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00091715 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00914706 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00034346 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00034346 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03901872 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT03347344 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study NCT01737346 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT01518985 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT00394355 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02491775 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02491775 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01188109 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT00981058 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00981058 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04543721 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04276675 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study NCT00116376 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00116376 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00116376 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01210404 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00953758 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study NCT03202381 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02325908 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03077672 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT02765074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02765074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02765074 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT03552341 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT01188083 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01188083 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01839864 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02926950 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00993031 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02170961 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02844114 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03615443 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT01206218 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00866138 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT03353857 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01325428 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00876135 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study NCT02090400 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01908660 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00000431 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study NCT01309178 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01569750 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03993184 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04012684 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study NCT04012684 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT03655964 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02175680 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT03612986 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02355028 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02355028 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02642198 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06700369 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06700369 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00651053 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT03784040 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02448732 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02448732 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04369066 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03304938 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01594216 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02149901 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01272063 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT00705549 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT00705549 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study NCT00705549 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02055066 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT00281879 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01147484 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01147484 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00362011 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01261156 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04057339 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02272725 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02272725 — Surrogate Endpoint (SUR): Serum sodium
Study NCT05932550 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT01474148 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT02135887 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT00366119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02806544 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01122797 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study NCT01318980 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study NCT00514683 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02595281 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT01975415 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00104923 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT02416284 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04469673 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04469673 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03603262 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03603262 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02820493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00046774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01584440 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT00802945 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT00493870 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00488982 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01955720 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT03952975 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT04735055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00554632 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00554632 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF