TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20096799 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16497598 — Surrogate Endpoint (SUR): Blood pressure
Study 10606836 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 2992264 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28812403 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21373936 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 16644317 — Surrogate Endpoint (SUR): Blood pressure
Study 16644317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29572190 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27050843 — Surrogate Endpoint (SUR): Bacterial count
Study 23088336 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23088336 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7969342 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 22246378 — Predictive Biomarker (PRD): PPARGC1A mRNA
Genes: PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1
Study 30855442 — Monitoring Biomarker (MOI): Procalcitonin
Study 25682077 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 6382991 — Surrogate Endpoint (SUR): Blood pressure
Study 22871173 — Surrogate Endpoint (SUR): Blood pressure
Study 20678689 — Surrogate Endpoint (SUR): Blood pressure
Study 20805137 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 16193890 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 25582493 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16039496 — Surrogate Endpoint (SUR): Blood pressure
Study 12525720 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 6740497 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25995301 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25995301 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15155304 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 8485068 — Surrogate Endpoint (SUR): Blood pressure
Study 18341818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18341818 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 14685056 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10590488 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21558878 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21558878 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21558878 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 21558878 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 21558878 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11508317 — Surrogate Endpoint (SUR): Blood pressure
Study 9124549 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9124549 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18824462 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18824462 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 18824462 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 16000605 — Predictive Biomarker (PRD): ALPI mRNA
Genes: ALPI
Study 9927017 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 7778023 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 7778023 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19443189 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9555866 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18028881 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8841865 — Surrogate Endpoint (SUR): Blood pressure
Study 30601161 — Surrogate Endpoint (SUR): Blood pressure
Study 26062189 — Surrogate Endpoint (SUR): Blood pressure
Study 15334503 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28794060 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19214137 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15156527 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11699048 — Surrogate Endpoint (SUR): Blood pressure
Study 10168562 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10168562 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21630126 — Surrogate Endpoint (SUR): Blood pressure
Study 16512939 — Surrogate Endpoint (SUR): Blood pressure
Study 16512939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16512939 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16512939 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3655305 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29498480 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 25737017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24040851 — Surrogate Endpoint (SUR): Blood pressure
Study 12933531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12933531 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12933531 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8268595 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12451199 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12451199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7573718 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 26313301 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 2119419 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 2119419 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2119419 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7435893 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 23473342 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 1845132 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1845132 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 6365209 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30081019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24385141 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 31928963 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31928963 — Predictive Biomarker (PRD): DIO2 mRNA
Genes: DIO2; ITDI2; TXDI2
Study 23531689 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study 23531689 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 15365580 — Predictive Biomarker (PRD): CRHR1 mRNA
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 24567516 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 24567516 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24567516 — Safety Biomarker (SAF): Vascular endothelial cadherin
Genes: CDH5
Study 24567516 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23113436 — Predictive Biomarker (PRD): APRT mRNA
Genes: APRT
Study 16213325 — Surrogate Endpoint (SUR): Serum uric acid
Study 11947912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11947912 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8574272 — Surrogate Endpoint (SUR): Blood pressure
Study 19264687 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 15466264 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 15466264 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23811645 — Surrogate Endpoint (SUR): Probing pocket depth
Study 9020426 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29081178 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26314275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23216710 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 16467100 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9312761 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27678426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27678426 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20136661 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16193347 — Surrogate Endpoint (SUR): Bone mineral density
Study 29502160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19655819 — Surrogate Endpoint (SUR): Blood pressure
Study 15222409 — Surrogate Endpoint (SUR): Blood pressure
Study 2514651 — Surrogate Endpoint (SUR): Blood pressure
Study 21048770 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21048770 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21048770 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1375873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1375873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29368187 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23061407 — Predictive Biomarker (PRD): GNB3 mRNA
Genes: GNB3
Study 15230300 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 7962669 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27103175 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 17165494 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 14592997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2042789 — Surrogate Endpoint (SUR): Blood pressure
Study 23715049 — Surrogate Endpoint (SUR): Blood pressure
Study 16606645 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 12950963 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 24439984 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24439984 — Surrogate Endpoint (SUR): Blood pressure
Study 10939029 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7033945 — Surrogate Endpoint (SUR): Blood pressure
Study 23127770 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23127770 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 23090292 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 23090292 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 20079321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8359179 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 28362327 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 28362327 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26293505 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29701119 — Surrogate Endpoint (SUR): Blood pressure
Study 20953211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18853110 — Safety Biomarker (SAF): Hyaluronic acid
Study 18853110 — Surrogate Endpoint (SUR): Serum creatinine
Study 16815741 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9640061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9640061 — Safety Biomarker (SAF): Interleukin 1
Study 31659986 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26968718 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 24631792 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24631792 — Surrogate Endpoint (SUR): Blood pressure
Study 22623389 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 22623389 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22623389 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 29665130 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 29665130 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 29665130 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 29665130 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 29665130 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 25100550 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 24075759 — Surrogate Endpoint (SUR): Blood pressure
Study 16501039 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15031570 — Surrogate Endpoint (SUR): Blood pressure
Study 9315764 — Surrogate Endpoint (SUR): Blood pressure
Study 24077325 — Safety Biomarker (SAF): Cytochrome c
Study 368088 — Surrogate Endpoint (SUR): Blood pressure
Study 24762094 — Surrogate Endpoint (SUR): Blood pressure
Study 15365963 — Surrogate Endpoint (SUR): Blood pressure
Study 10452470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10452470 — Surrogate Endpoint (SUR): Serum creatinine
Study 7872342 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7872342 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23863909 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 17082991 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 15571006 — Safety Biomarker (SAF): Hyaluronic acid
Study 26869148 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 25302852 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 25302852 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23870670 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 8762211 — Surrogate Endpoint (SUR): Blood pressure
Study 11907490 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 11907490 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 11907490 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11907490 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30392473 — Surrogate Endpoint (SUR): Blood pressure
Study 21549069 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 367457 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 29308939 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 27749236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26176044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26176044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12546581 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 6863881 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27011257 — Surrogate Endpoint (SUR): Blood pressure
Study 26338739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23110500 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23110500 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18837197 — Surrogate Endpoint (SUR): Blood pressure
Study 16247790 — Surrogate Endpoint (SUR): Blood pressure
Study 7488771 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7488771 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 7488771 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 7488771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7488771 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15642080 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15642080 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9973093 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24415271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18305954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18305954 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 18305954 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7730247 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7730247 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7730247 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31688449 — Safety Biomarker (SAF): DRD2
Study 11585103 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28655351 — Predictive Biomarker (PRD): SAGE1 mRNA
Genes: SAGE1; SAGE
Study 15608803 — Surrogate Endpoint (SUR): Blood pressure
Study 24159562 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 21367849 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21367849 — Surrogate Endpoint (SUR): Serum creatinine
Study 11967729 — Surrogate Endpoint (SUR): Blood pressure
Study 10101728 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26007202 — Surrogate Endpoint (SUR): Blood pressure
Study 12296888 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25891115 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 25891115 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21248159 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 11874551 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 17554786 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 8354027 — Surrogate Endpoint (SUR): Blood pressure
Study 27727279 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27727279 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22129171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16611307 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 12954577 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9187994 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9187994 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17593869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17593869 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17593869 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15610655 — Predictive Biomarker (PRD): HES1 mRNA
Genes: HES1; BHLHB39; HL; HRY
Study 10782751 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7735583 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20813792 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 20813792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15890561 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23368827 — Surrogate Endpoint (SUR): Blood pressure
Study 23368827 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23368827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21993710 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21993710 — Surrogate Endpoint (SUR): Serum creatinine
Study 21993710 — Surrogate Endpoint (SUR): Blood pressure
Study 18798500 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21956960 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21956960 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12077088 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7593704 — Surrogate Endpoint (SUR): Bacterial count
Study 31397702 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 21197524 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 19414940 — Surrogate Endpoint (SUR): Serum potassium
Study 7848901 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7848901 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12694150 — Surrogate Endpoint (SUR): Blood pressure
Study 10731509 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22689677 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31593081 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 28291838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26116999 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 26116999 — Surrogate Endpoint (SUR): Blood pressure
Study 9179367 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 9179367 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 9179367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9179367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9179367 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG