TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22855271 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 28293470 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26430826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26430826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21830124 — Surrogate Endpoint (SUR): Blood pressure
Study 17309575 — Surrogate Endpoint (SUR): Blood pressure
Study 15112344 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 15112344 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9660327 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23344468 — Surrogate Endpoint (SUR): Blood pressure
Study 19258723 — Surrogate Endpoint (SUR): Blood pressure
Study 9165360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9165360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9165360 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 3315282 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 21109115 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15910869 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 12714865 — Surrogate Endpoint (SUR): Blood pressure
Study 26048730 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21716593 — Surrogate Endpoint (SUR): Bone mineral density
Study 19347740 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30211823 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 22172243 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18586898 — Surrogate Endpoint (SUR): Blood pressure
Study 10494584 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30783735 — Surrogate Endpoint (SUR): Blood pressure
Study 7754988 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28976249 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 16809571 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12777860 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 12777860 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 8603263 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29804552 — Surrogate Endpoint (SUR): Bacterial count
Study 22057726 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16785075 — Surrogate Endpoint (SUR): Bone mineral density
Study 18192779 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12911201 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12911201 — Surrogate Endpoint (SUR): Blood pressure
Study 23039403 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23039403 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16422313 — Surrogate Endpoint (SUR): Blood pressure
Study 10584041 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 10584041 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2009789 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 7010650 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22972168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15118187 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9498442 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28566363 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25376930 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Cholinesterase
Genes: BCHE; CHE1
Study 25376930 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24195218 — Surrogate Endpoint (SUR): Blood pressure
Study 17046467 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20885427 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7656956 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28654304 — Predictive Biomarker (PRD): CDON mRNA
Genes: CDON; CDO
Study 25453567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16780979 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 31217344 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31217344 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31217344 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 14704262 — Surrogate Endpoint (SUR): Blood pressure
Study 11412219 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9220037 — Surrogate Endpoint (SUR): Blood pressure
Study 8432777 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11174477 — Surrogate Endpoint (SUR): Blood pressure
Study 22972566 — Surrogate Endpoint (SUR): Blood pressure
Study 18959799 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 18959799 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 9055055 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9055055 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16988138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26873229 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 26873229 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24509626 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 12195876 — Monitoring Biomarker (MOI): HBV DNA
Study 7534055 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 678387 — Surrogate Endpoint (SUR): Blood pressure
Study 30309970 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 25710801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25710801 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 4014048 — Surrogate Endpoint (SUR): Blood pressure
Study 30184110 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27931551 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24200748 — Surrogate Endpoint (SUR): Blood pressure
Study 23332861 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21715530 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 19228745 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12775857 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 12905476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9797093 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9797093 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24743444 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24743444 — Surrogate Endpoint (SUR): Blood pressure
Study 15777442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11949775 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 28408372 — Safety Biomarker (SAF): Reactive oxygen species
Study 28000127 — Surrogate Endpoint (SUR): Blood pressure
Study 16556888 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 1620416 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25934015 — Surrogate Endpoint (SUR): Blood pressure
Study 25135383 — Surrogate Endpoint (SUR): Blood pressure
Study 29492753 — Predictive Biomarker (PRD): Hormone receptor
Study 15244109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10172084 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 22717018 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 22717018 — Predictive Biomarker (PRD): HTR1B mRNA
Genes: HTR1B; HTR1DB
Study 18224344 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10505694 — Safety Biomarker (SAF): Interleukin 12
Study 10505694 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31902653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31902653 — Surrogate Endpoint (SUR): Blood pressure
Study 31498922 — Surrogate Endpoint (SUR): Bone mineral density
Study 27262086 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 17665244 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15799006 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12002769 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12002769 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study 12002769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25934864 — Surrogate Endpoint (SUR): Blood pressure
Study 25934864 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18844082 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18844082 — Surrogate Endpoint (SUR): Bone mineral density
Study 8773636 — Surrogate Endpoint (SUR): Serum calcium
Study 1734637 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15753963 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9886795 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9886795 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 9886795 — Surrogate Endpoint (SUR): Serum creatinine
Study 9886795 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2516122 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 31980512 — Surrogate Endpoint (SUR): Blood pressure
Study 2890268 — Surrogate Endpoint (SUR): Blood pressure
Study 2890268 — Surrogate Endpoint (SUR): Serum potassium
Study 16284462 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 387329 — Surrogate Endpoint (SUR): Blood pressure
Study 31950134 — Surrogate Endpoint (SUR): Blood pressure
Study 28207168 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21330034 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11049793 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24667381 — Surrogate Endpoint (SUR): Blood pressure
Study 22645201 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22645201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22645201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22645201 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19960352 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19960352 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 3105477 — Surrogate Endpoint (SUR): Blood pressure
Study 16449618 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16449618 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 16522693 — Predictive Biomarker (PRD): Hormone receptor
Study 16522693 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16522693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16531613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16554527 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 16681848 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16681848 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16709929 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 16758521 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16758521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16758521 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16775234 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 16775234 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 16775235 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 16775235 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 16855264 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 16864722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16882711 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 16885550 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study 16899778 — Safety Biomarker (SAF): Interleukin 1
Study 16899778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16905786 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16921041 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 16925569 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 16925569 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 16943394 — Surrogate Endpoint (SUR): Blood pressure
Study 16952304 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 16952304 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 16952304 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 16959033 — Surrogate Endpoint (SUR): Blood pressure
Study 17010801 — Predictive Biomarker (PRD): PLN mRNA
Genes: PLN; PLB
Study 17021321 — Predictive Biomarker (PRD): Chromosome 5q
Study 17130304 — Surrogate Endpoint (SUR): Blood pressure
Study 17161253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17161253 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17161253 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17164793 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17164793 — Predictive Biomarker (PRD): FANCA mRNA
Genes: FANCA; FAA; FACA; FANCH
Study 17242628 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17251666 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17258088 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 17276184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17278106 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 17278106 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17296644 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17310025 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17310025 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17332146 — Safety Biomarker (SAF): MTHFR
Study 17351381 — Surrogate Endpoint (SUR): Serum creatinine
Study 17351381 — Surrogate Endpoint (SUR): Blood pressure
Study 17356709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17362525 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 17362525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17362525 — Monitoring Biomarker (MOI): Procalcitonin
Study 17379851 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17395103 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 17418291 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17418291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17431579 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor delta
Genes: PPARD
Study 17436219 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17450048 — Predictive Biomarker (PRD): MAP9 mRNA
Genes: MAP9; ASAP
Study 17462825 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 17498579 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17512363 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17519207 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17536019 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 17536019 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 17541653 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 17544766 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17557758 — Surrogate Endpoint (SUR): Bone mineral density
Study 17558345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17558345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17559726 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17559726 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 17560635 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 17562873 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study 17573503 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17573882 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 17579195 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17586030 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17586305 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17591525 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17592632 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17592632 — Surrogate Endpoint (SUR): Blood pressure
Study 17596541 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 17596541 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 17597266 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17609424 — Predictive Biomarker (PRD): PSMB9 mRNA
Genes: PSMB9; LMP2; PSMB6i; RING12
Study 17626713 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17626713 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17634466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17635942 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17635942 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17635942 — Surrogate Endpoint (SUR): Blood pressure
Study 17643576 — Surrogate Endpoint (SUR): Serum creatinine
Study 17646603 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17647221 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17662149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17662149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17662149 — Surrogate Endpoint (SUR): Bone mineral density
Study 17673691 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17679671 — Predictive Biomarker (PRD): Tripeptidyl-peptidase I
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study 17679729 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 17679729 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17686822 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17699416 — Surrogate Endpoint (SUR): Serum creatinine
Study 17704543 — Surrogate Endpoint (SUR): Blood pressure
Study 17707182 — Predictive Biomarker (PRD): SFPQ mRNA
Genes: SFPQ; PSF
Study 17707182 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17709602 — Predictive Biomarker (PRD): FIP1L1 mRNA
Genes: FIP1L1; FIP1; RHE
Study 17709602 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 17713466 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17713466 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17713466 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ESR2 mRNA
Genes: ESR2; ESTRB; NR3A2
Study 17715389 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 17715389 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 17727882 — Predictive Biomarker (PRD): SLC22A3 mRNA
Genes: SLC22A3; EMTH; OCT3
Study 17761710 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 17822557 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17846226 — Safety Biomarker (SAF): Interleukin 12
Study 17846226 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17875804 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 17875804 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17892636 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17892636 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17893227 — Predictive Biomarker (PRD): Chromosome 5q
Study 17910637 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34