TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26069290 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 31256014 — Predictive Biomarker (PRD): ZMYM2 mRNA
Genes: ZMYM2; FIM; RAMP; ZNF198
Study 22446171 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 22446171 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 16646004 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11381289 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30016335 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 30016335 — Monitoring Biomarker (MOI): HBV DNA
Study 22522403 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 22522403 — Surrogate Endpoint (SUR): Blood pressure
Study 30318065 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20415638 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6367368 — Surrogate Endpoint (SUR): Serum uric acid
Study 6367368 — Surrogate Endpoint (SUR): Blood pressure
Study 19778661 — Surrogate Endpoint (SUR): Blood pressure
Study 8141172 — Surrogate Endpoint (SUR): Blood pressure
Study 8141172 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30160543 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16527863 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16527863 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 16527863 — Predictive Biomarker (PRD): SPR mRNA
Genes: SPR
Study 10965516 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26674992 — Surrogate Endpoint (SUR): Blood pressure
Study 23524367 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 12642710 — Surrogate Endpoint (SUR): Bone mineral density
Study 28891251 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 22178274 — Safety Biomarker (SAF): Hyaluronic acid
Study 11704586 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11704586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 11704586 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 12810925 — Predictive Biomarker (PRD): NOD2 mRNA
Genes: NOD2; CARD15; IBD1
Study 7847434 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27458060 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14739797 — Surrogate Endpoint (SUR): Blood pressure
Study 3357722 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24753831 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 21769731 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19329822 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19329822 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14704596 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3081148 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3081148 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9497790 — Surrogate Endpoint (SUR): Blood pressure
Study 19209184 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19209184 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9543170 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23456697 — Surrogate Endpoint (SUR): Blood pressure
Study 19665275 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9271481 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31237187 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 20145786 — Safety Biomarker (SAF): Hyaluronic acid
Study 16768551 — Surrogate Endpoint (SUR): Blood pressure
Study 15076173 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15076173 — Surrogate Endpoint (SUR): Blood pressure
Study 11126502 — Surrogate Endpoint (SUR): Blood pressure
Study 9333514 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 9333514 — Surrogate Endpoint (SUR): Blood pressure
Study 9333514 — Surrogate Endpoint (SUR): Serum potassium
Study 8475234 — Surrogate Endpoint (SUR): Blood pressure
Study 28185407 — Surrogate Endpoint (SUR): Blood pressure
Study 19651171 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9854507 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24732290 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21848172 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 14976881 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 14976881 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 14976881 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8633187 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8633187 — Surrogate Endpoint (SUR): Blood pressure
Study 2568838 — Surrogate Endpoint (SUR): Blood pressure
Study 31378394 — Surrogate Endpoint (SUR): Blood pressure
Study 24647908 — Safety Biomarker (SAF): Reactive oxygen species
Study 19944392 — Surrogate Endpoint (SUR): Serum creatinine
Study 11858491 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 24020372 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15502050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28987470 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 28987470 — Safety Biomarker (SAF): Interleukin 1
Study 9440743 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 2914540 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 4736626 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31776293 — Predictive Biomarker (PRD): DGAT2 mRNA
Genes: DGAT2; HMFN1045; UNQ738/PRO1433
Study 19927026 — Safety Biomarker (SAF): Cytochrome c
Study 19927026 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 7639505 — Surrogate Endpoint (SUR): Blood pressure
Study 7639505 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 736633 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 15023936 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 15023936 — Surrogate Endpoint (SUR): Blood pressure
Study 11772257 — Predictive Biomarker (PRD): PDE4D mRNA
Genes: PDE4D; DPDE3
Study 11772257 — Predictive Biomarker (PRD): PDE4A mRNA
Genes: PDE4A; DPDE2
Study 26489030 — Predictive Biomarker (PRD): KCNE1 mRNA
Genes: KCNE1
Study 16390351 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11174009 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11174009 — Surrogate Endpoint (SUR): Blood pressure
Study 8299431 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8299431 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27040132 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27040132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27040132 — Surrogate Endpoint (SUR): Blood pressure
Study 20861207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20861207 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11789208 — Surrogate Endpoint (SUR): Blood pressure
Study 20152239 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1719708 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1719708 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25872972 — Surrogate Endpoint (SUR): Bone mineral density
Study 19462498 — Surrogate Endpoint (SUR): Blood pressure
Study 17261454 — Surrogate Endpoint (SUR): Blood pressure
Study 15161690 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 15161690 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15161690 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9872248 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31912780 — Surrogate Endpoint (SUR): Blood pressure
Study 19342206 — Surrogate Endpoint (SUR): Blood pressure
Study 11593098 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24659472 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 17701685 — Surrogate Endpoint (SUR): Blood pressure
Study 14980748 — Surrogate Endpoint (SUR): Blood pressure
Study 9524044 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9524044 — Surrogate Endpoint (SUR): Blood pressure
Study 31785830 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25969453 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 22339103 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 22339103 — Surrogate Endpoint (SUR): Blood pressure
Study 8736278 — Surrogate Endpoint (SUR): Bone mineral density
Study 25877812 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 20671330 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 28564127 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 10686803 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6125181 — Surrogate Endpoint (SUR): Blood pressure
Study 15326115 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15326115 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 9690480 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 27403851 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 27403851 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 27403851 — Safety Biomarker (SAF): DRD2
Study 25060669 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26734954 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26734954 — Surrogate Endpoint (SUR): Blood pressure
Study 26734954 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26734954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22848584 — Surrogate Endpoint (SUR): Blood pressure
Study 16045013 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 16045013 — Surrogate Endpoint (SUR): Blood pressure
Study 27225338 — Surrogate Endpoint (SUR): Serum calcium
Study 18616780 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 7519032 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 20644943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20644943 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15140780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9821562 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 23368826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23368826 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20579847 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 19279365 — Predictive Biomarker (PRD): P4HB mRNA
Genes: P4HB; ERBA2L; PDI; PDIA1; PO4DB
Study 11463988 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22550196 — Surrogate Endpoint (SUR): Blood pressure
Study 15744147 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27681572 — Surrogate Endpoint (SUR): Blood pressure
Study 6357901 — Surrogate Endpoint (SUR): Blood pressure
Study 17484872 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 31036580 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study 22196270 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 15682684 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15682684 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 29191585 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10671339 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22901955 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20536619 — Surrogate Endpoint (SUR): Blood pressure
Study 12145999 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 30677646 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19196111 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8352424 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3112727 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 27192969 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 27192969 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 20570883 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20570883 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12803737 — Surrogate Endpoint (SUR): Blood pressure
Study 15886669 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 12097537 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27183922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27183922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22855206 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22855206 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 19661927 — Surrogate Endpoint (SUR): Blood pressure
Study 2282920 — Surrogate Endpoint (SUR): Blood pressure
Study 22083873 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12529549 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 12529549 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12529549 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 12529549 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 10949811 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 4072599 — Safety Biomarker (SAF): Hyaluronic acid
Study 26575158 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 25063191 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 18360068 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12593493 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12593493 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10593132 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30328108 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 28078862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28078862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28078862 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28078862 — Surrogate Endpoint (SUR): Blood pressure
Study 28078862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17413560 — Surrogate Endpoint (SUR): Blood pressure
Study 29202488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29202488 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29202488 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29202488 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29202488 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22027699 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9188761 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9188761 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 8442581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27622723 — Predictive Biomarker (PRD): UGT2B15 mRNA
Genes: UGT2B15; UGT2B8
Study 18575626 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 16042882 — Monitoring Biomarker (MOI): HBV DNA
Study 31077181 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21360715 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25226311 — Surrogate Endpoint (SUR): Blood pressure
Study 16728541 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 16728541 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 16728541 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 10620131 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10620131 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28024961 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28024961 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 1839430 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25158081 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 12444212 — Predictive Biomarker (PRD): CLCN5 mRNA
Genes: CLCN5; CLCK2
Study 9660361 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17097995 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31834549 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 16299646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16299646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12577189 — Surrogate Endpoint (SUR): Bone mineral density
Study 26903399 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26903399 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23877659 — Predictive Biomarker (PRD): TPBG mRNA
Genes: TPBG; 5T4
Study 23877659 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 14974908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14974908 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10801290 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18622656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18622656 — Predictive Biomarker (PRD): CBLIF mRNA
Genes: CBLIF; GIF; IFMH
Study 9704681 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29325594 — Predictive Biomarker (PRD): IFT122 mRNA
Genes: IFT122; SPG; WDR10; WDR140
Study 8522681 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23602205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23602205 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23602205 — Safety Biomarker (SAF): BDNF
Study 23602205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22473155 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 12972682 — Surrogate Endpoint (SUR): Blood pressure
Study 8804944 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19327952 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 16169399 — Surrogate Endpoint (SUR): Sperm parameters
Study 8678279 — Surrogate Endpoint (SUR): Blood pressure
Study 23971720 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23971720 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12740739 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 6510544 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6510544 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30825465 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 12651660 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 9215287 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3315270 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 22092475 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 11110737 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8334029 — Surrogate Endpoint (SUR): Serum creatinine
Study 26367325 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22682911 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 22682911 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 17606861 — Surrogate Endpoint (SUR): Blood pressure
Study 10192750 — Surrogate Endpoint (SUR): Blood pressure
Study 2182945 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 232017 — Surrogate Endpoint (SUR): Blood pressure
Study 232017 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30058344 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 21671413 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 9657627 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9657627 — Surrogate Endpoint (SUR): Blood pressure
Study 12891310 — Surrogate Endpoint (SUR): Blood pressure
Study 6405346 — Surrogate Endpoint (SUR): Blood pressure
Study 28319467 — Surrogate Endpoint (SUR): Blood pressure
Study 23446330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11578293 — Surrogate Endpoint (SUR): Serum creatinine
Study 11578293 — Surrogate Endpoint (SUR): Blood pressure
Study 21329776 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8832535 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4