TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04554719 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT00002539 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00570193 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05935501 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03360461 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02240355 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT00858637 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00858637 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT03403725 — Predictive Biomarker (PRD): LY75 mRNA
Genes: LY75; CD205; CLEC13B
Study NCT00000529 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01630629 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04180332 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT02896855 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01515813 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01515813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01925716 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02014857 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study NCT03070002 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02673125 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT00166439 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02396355 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01178151 — Predictive Biomarker (PRD): STK11 mRNA
Genes: STK11; LKB1; PJS
Study NCT01178151 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study NCT01013857 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04269928 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04269928 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02955537 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04601155 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01985841 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00172172 — Predictive Biomarker (PRD): ALX1 mRNA
Genes: ALX1; CART1
Study NCT00172172 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01629758 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study NCT02715089 — Predictive Biomarker (PRD): TP53INP2 mRNA
Genes: TP53INP2; C20orf110; DOR; PINH
Study NCT00003199 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03722394 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT01287260 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04198155 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01925547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01925547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01925547 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT04489472 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02411435 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00077025 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02999776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02700282 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04589923 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04345315 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03909308 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00249938 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04470596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04470596 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study NCT03813329 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01289860 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02838368 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT01539616 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT01026974 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study NCT03839862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02161991 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03255551 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03896581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00795717 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03322410 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01930838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03258775 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02758431 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001813 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT04239742 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04216472 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04216472 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03781778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00252408 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04420247 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00728091 — Surrogate Endpoint (SUR): Serum sodium
Study NCT00108316 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT02172378 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02861898 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03570177 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02116634 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00770809 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02412735 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01736813 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02032472 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00640497 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT00342849 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00288158 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03649828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03649828 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01986166 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03671330 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03671330 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01854034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03389802 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT00852904 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03355079 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02825589 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00694239 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03083301 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01732276 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01732276 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06784453 — Predictive Biomarker (PRD): TYMP mRNA
Genes: TYMP; ECGF1
Study NCT06784453 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04401241 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04401241 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01700608 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT01700608 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01700608 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01493024 — Surrogate Endpoint (SUR): Serum potassium
Study NCT04034342 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01899079 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02863640 — Predictive Biomarker (PRD): FFAR2 mRNA
Genes: FFAR2; FFA2; GPCR43; GPR43
Study NCT02276300 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03674177 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00291603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00291603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04105023 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT00651638 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01856582 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00325793 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01579708 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03700567 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study NCT03620942 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01432119 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01432119 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01843062 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT02218437 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00001651 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04398303 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03848533 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01714128 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT01714128 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03652753 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03103555 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03761901 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03761901 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02669212 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02735343 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04305171 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT04305171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00132808 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02534857 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04124705 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02877303 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT05037019 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03750929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00386906 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT03942458 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03916796 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT01603888 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02629510 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03681028 — Predictive Biomarker (PRD): RHOH mRNA
Genes: RHOH; ARHH; TTF
Study NCT03911492 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01862497 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01885247 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT00897221 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT00352430 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06330259 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01777919 — Predictive Biomarker (PRD): ALDH1A1 mRNA
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study NCT02487004 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00455221 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00455221 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02849470 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study NCT02749565 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02749565 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study NCT02749565 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02095080 — Surrogate Endpoint (SUR): Plasma ammonia
Study NCT02562755 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04112043 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03844763 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03574168 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01134640 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01134640 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01134640 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00166504 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04382209 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01188304 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04342117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01737216 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00002913 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03744507 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02628353 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01966913 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01966913 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04269876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04269876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04269876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01321372 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01991327 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01991327 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01991327 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01991327 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01991327 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04176016 — Predictive Biomarker (PRD): FZD10 mRNA
Genes: FZD10
Study NCT00897455 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00897455 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02830815 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study NCT03861832 — Predictive Biomarker (PRD): GARS1 mRNA
Genes: GARS1; GARS
Study NCT01743560 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01825967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00581477 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00371241 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study NCT01735175 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT01059422 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT02288663 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01142960 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02860676 — Predictive Biomarker (PRD): RORA
Genes: RZRA; ROR1; ROR2; ROR3; NR1F1; ROR-alpha; RORalpha; RORa1
Study NCT04479202 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04479202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04479202 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01742767 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01742767 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05456971 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01806909 — Predictive Biomarker (PRD): VTN mRNA
Genes: VTN
Study NCT02184858 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01865448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01865448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01287507 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study NCT02529046 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT05257291 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03654508 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study NCT00328419 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01712061 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT04137185 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04192110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04446754 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study NCT03761238 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study NCT02108769 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT00082550 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT03719105 — Predictive Biomarker (PRD): PRX mRNA
Genes: PRX; KIAA1620
Study NCT01610336 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01610336 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01928901 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT01689415 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03596593 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT03596593 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02590354 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02020538 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01128244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00891228 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study NCT02162602 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT02162602 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00689728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00567359 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00567359 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05033106 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00461773 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02386163 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01870115 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02533492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00005268 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02373579 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03643549 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT02529774 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study NCT02828436 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01510158 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03507166 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00990223 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02152943 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02152943 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02152943 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03822013 — Predictive Biomarker (PRD): HEXA mRNA
Genes: HEXA
Study NCT02400593 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00694109 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02534324 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01494077 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00313105 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00345865 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00218270 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03045523 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04473027 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO