TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20387250 — Surrogate Endpoint (SUR): Blood pressure
Study 10805056 — Surrogate Endpoint (SUR): Blood pressure
Study 27302510 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8758093 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8758093 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20554790 — Surrogate Endpoint (SUR): Bone mineral density
Study 24219579 — Surrogate Endpoint (SUR): Serum uric acid
Study 14504184 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14504184 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11099761 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 27015578 — Surrogate Endpoint (SUR): Blood pressure
Study 24662864 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24662864 — Surrogate Endpoint (SUR): Blood pressure
Study 8569975 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 28383400 — Surrogate Endpoint (SUR): Blood pressure
Study 24078335 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 24078335 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 19204301 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15045504 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 12654211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28791787 — Surrogate Endpoint (SUR): Blood pressure
Study 25293480 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20226843 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8831918 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 8831918 — Predictive Biomarker (PRD): HES1 mRNA
Genes: HES1; BHLHB39; HL; HRY
Study 27888575 — Surrogate Endpoint (SUR): Blood pressure
Study 15312097 — Surrogate Endpoint (SUR): Probing pocket depth
Study 27439969 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 27439969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18271842 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 15693603 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 6990946 — Surrogate Endpoint (SUR): Blood pressure
Study 26476086 — Surrogate Endpoint (SUR): Blood pressure
Study 2724027 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 24829088 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24829088 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22689678 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22689678 — Safety Biomarker (SAF): Reactive oxygen species
Study 16087995 — Surrogate Endpoint (SUR): Bone mineral density
Study 30689664 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 28903122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24793535 — Surrogate Endpoint (SUR): Serum calcium
Study 22551909 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 7598995 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 7598995 — Predictive Biomarker (PRD): BSN mRNA
Genes: BSN; KIAA0434; ZNF231
Study 23294500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18997444 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9231890 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9231890 — Surrogate Endpoint (SUR): Blood pressure
Study 29043411 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19486119 — Surrogate Endpoint (SUR): Blood pressure
Study 8320430 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25023786 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 22960764 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 22960764 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18362764 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 25156987 — Surrogate Endpoint (SUR): Blood pressure
Study 25156987 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6164480 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 6164480 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 27777261 — Surrogate Endpoint (SUR): Blood pressure
Study 10681340 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 9192194 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30073585 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23318610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15939519 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31530055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31530055 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22858806 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19203563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15172263 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8462317 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 30145817 — Predictive Biomarker (PRD): LGALSL mRNA
Genes: LGALSL; GRP; HSPC159
Study 10403616 — Surrogate Endpoint (SUR): Blood pressure
Study 7720941 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 2039640 — Surrogate Endpoint (SUR): Blood pressure
Study 27631821 — Surrogate Endpoint (SUR): Serum creatinine
Study 26445777 — Surrogate Endpoint (SUR): Serum sodium
Study 26445777 — Surrogate Endpoint (SUR): Serum potassium
Study 31339677 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28182218 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 19519298 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 3806153 — Surrogate Endpoint (SUR): Blood pressure
Study 25494205 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25494205 — Surrogate Endpoint (SUR): Blood pressure
Study 22118569 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 2889306 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 16409560 — Surrogate Endpoint (SUR): Blood pressure
Study 16409560 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9480237 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8201970 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 22313587 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12898439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12898439 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 12898439 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2772038 — Surrogate Endpoint (SUR): Blood pressure
Study 799927 — Surrogate Endpoint (SUR): Blood pressure
Study 31864519 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 1327051 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1327051 — Surrogate Endpoint (SUR): Blood pressure
Study 28453765 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 28453765 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26641456 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 29528792 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 28126333 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 8944697 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8944697 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 6758743 — Surrogate Endpoint (SUR): Blood pressure
Study 31301436 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24075621 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 31594196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27418545 — Surrogate Endpoint (SUR): Blood pressure
Study 9252738 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16440115 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11419768 — Surrogate Endpoint (SUR): Blood pressure
Study 11419768 — Surrogate Endpoint (SUR): Serum creatinine
Study 23306362 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 23306362 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 21688030 — Surrogate Endpoint (SUR): Blood pressure
Study 16615978 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 22494866 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19398001 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1781822 — Surrogate Endpoint (SUR): Serum creatinine
Study 7293938 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19641980 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19641980 — Surrogate Endpoint (SUR): Blood pressure
Study 8283895 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8283895 — Surrogate Endpoint (SUR): Blood pressure
Study 28393317 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 21812820 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18504447 — Surrogate Endpoint (SUR): Blood pressure
Study 12707160 — Surrogate Endpoint (SUR): Blood pressure
Study 15878467 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 9616258 — Surrogate Endpoint (SUR): Blood pressure
Study 24351495 — Surrogate Endpoint (SUR): Blood pressure
Study 18469248 — Surrogate Endpoint (SUR): Urinary oxalate
Study 10437188 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20581392 — Surrogate Endpoint (SUR): Total kidney volume
Study 12657404 — Surrogate Endpoint (SUR): Blood pressure
Study 27797674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27797674 — Surrogate Endpoint (SUR): Blood pressure
Study 26001289 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study 26001289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26001289 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19194127 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27058964 — Safety Biomarker (SAF): Hyaluronic acid
Study 22846453 — Surrogate Endpoint (SUR): Blood pressure
Study 22846453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11994561 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 30215460 — Surrogate Endpoint (SUR): Blood pressure
Study 22823027 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 22823027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22823027 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19106322 — Surrogate Endpoint (SUR): Blood pressure
Study 15492316 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 15492316 — Predictive Biomarker (PRD): AGTR2 mRNA
Genes: AGTR2
Study 15492316 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15492316 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 23998969 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26360770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26360770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11811547 — Surrogate Endpoint (SUR): Blood pressure
Study 9515998 — Surrogate Endpoint (SUR): Blood pressure
Study 7775548 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24955456 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 24955456 — Monitoring Biomarker (MOI): HBV DNA
Study 17140970 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27310943 — Safety Biomarker (SAF): DRD3
Study 22033719 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 15674316 — Surrogate Endpoint (SUR): Serum creatinine
Study 15674316 — Surrogate Endpoint (SUR): Serum calcium
Study 15674316 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 15674316 — Surrogate Endpoint (SUR): Serum phosphate
Study 31878810 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17855483 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15881863 — Monitoring Biomarker (MOI): HBV DNA
Study 12053586 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 12053586 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29499728 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 31362773 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 21404051 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21404051 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 21665421 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 10412777 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10412777 — Surrogate Endpoint (SUR): Serum creatinine
Study 29282336 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12736841 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1939943 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 30918320 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30918320 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30918320 — Surrogate Endpoint (SUR): Serum creatinine
Study 788743 — Surrogate Endpoint (SUR): Blood pressure
Study 21292602 — Surrogate Endpoint (SUR): Blood pressure
Study 16759923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16759923 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15099277 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9803197 — Surrogate Endpoint (SUR): Blood pressure
Study 30653851 — Predictive Biomarker (PRD): S100A4 mRNA
Genes: S100A4; CAPL; MTS1
Study 6094104 — Surrogate Endpoint (SUR): Blood pressure
Study 6988713 — Surrogate Endpoint (SUR): Serum creatinine
Study 26924303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26924303 — Surrogate Endpoint (SUR): Blood pressure
Study 26924303 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26924303 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26924303 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26506968 — Surrogate Endpoint (SUR): Blood pressure
Study 26506968 — Surrogate Endpoint (SUR): Serum creatinine
Study 21221773 — Surrogate Endpoint (SUR): Bone mineral density
Study 19369178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7752863 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30116543 — Surrogate Endpoint (SUR): Serum creatinine
Study 22362918 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17350856 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16298736 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25741153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18979719 — Surrogate Endpoint (SUR): Blood pressure
Study 16984212 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10969351 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10969351 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8956766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14642684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14642684 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 14642684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22490404 — Surrogate Endpoint (SUR): Blood pressure
Study 20602497 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 20108171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20108171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20108171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11926969 — Surrogate Endpoint (SUR): Blood pressure
Study 12088811 — Surrogate Endpoint (SUR): Blood pressure
Study 31481110 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 26545677 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18801802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18801802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18801802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18801802 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29696921 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 24718282 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 8839667 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 28595367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24419307 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 12405434 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10091789 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22850760 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 22850760 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 1376847 — Surrogate Endpoint (SUR): Blood pressure
Study 22449251 — Monitoring Biomarker (MOI): HBV DNA
Study 18698234 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 11438563 — Predictive Biomarker (PRD): Hormone receptor
Study 8000218 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 23193009 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21972403 — Surrogate Endpoint (SUR): Serum creatinine
Study 19928484 — Surrogate Endpoint (SUR): Bone mineral density
Study 15221928 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 9296944 — Surrogate Endpoint (SUR): Blood pressure
Study 27577546 — Predictive Biomarker (PRD): SHANK3 mRNA
Genes: SHANK3; KIAA1650; PROSAP2; PSAP2
Study 25240121 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 14504627 — Surrogate Endpoint (SUR): Blood pressure
Study 6846212 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6846212 — Surrogate Endpoint (SUR): Blood pressure
Study 6846212 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30540689 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30540689 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20350641 — Predictive Biomarker (PRD): SPTB mRNA
Genes: SPTB; SPTB1
Study 12435472 — Surrogate Endpoint (SUR): Blood pressure
Study 6138934 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2984397 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 2984397 — Monitoring Biomarker (MOI): Complement C4
Study 24315894 — Surrogate Endpoint (SUR): Blood pressure
Study 16472379 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 26497960 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26497960 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26497960 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19528562 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19528562 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17151968 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10338218 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 20538669 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19018915 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7113949 — Surrogate Endpoint (SUR): Serum calcium
Study 7113949 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30702971 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 30702971 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25872531 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23645323 — Surrogate Endpoint (SUR): Blood pressure
Study 20528697 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 12867685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18653575 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28187400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22527138 — Surrogate Endpoint (SUR): Bone mineral density
Study 22073889 — Predictive Biomarker (PRD): SI mRNA
Genes: SI