TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28083711 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 24735962 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 16448896 — Surrogate Endpoint (SUR): Blood pressure
Study 12883365 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10068575 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24026542 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21121833 — Predictive Biomarker (PRD): Hormone receptor
Study 10438346 — Monitoring Biomarker (MOI): HBV DNA
Study 29787472 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 10354291 — Surrogate Endpoint (SUR): Serum creatinine
Study 31819291 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 12521404 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28741050 — Surrogate Endpoint (SUR): Serum creatinine
Study 28741050 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25716539 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 25716539 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 15665769 — Surrogate Endpoint (SUR): Serum creatinine
Study 15665769 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 15665769 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15665769 — Surrogate Endpoint (SUR): Blood pressure
Study 25495887 — Predictive Biomarker (PRD): PRKACA mRNA
Genes: PRKACA; PKACA
Study 25495887 — Predictive Biomarker (PRD): PRKCI mRNA
Genes: PRKCI; DXS1179E
Study 25495887 — Predictive Biomarker (PRD): SNAP23 mRNA
Genes: SNAP23
Study 25495887 — Predictive Biomarker (PRD): TRAK2 mRNA
Genes: TRAK2; ALS2CR3; KIAA0549
Study 15939844 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7533345 — Surrogate Endpoint (SUR): Serum creatinine
Study 28522181 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23356861 — Surrogate Endpoint (SUR): Blood pressure
Study 26182059 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16734597 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 8602314 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20046170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18419949 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 10394020 — Surrogate Endpoint (SUR): Serum creatinine
Study 19479852 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19479852 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19479852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24707475 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 22144539 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17666602 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28701597 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24046430 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21929764 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9344167 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 23506581 — Surrogate Endpoint (SUR): Blood pressure
Study 21885675 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24959347 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12862135 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 8831305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8831305 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 3100312 — Surrogate Endpoint (SUR): Serum calcium
Study 3100312 — Surrogate Endpoint (SUR): Serum creatinine
Study 29596311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24958603 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 24958603 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21160258 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21160258 — Predictive Biomarker (PRD): Hormone receptor
Study 15988077 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31334793 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29584549 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22577718 — Surrogate Endpoint (SUR): Bone mineral density
Study 16274306 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 10442322 — Surrogate Endpoint (SUR): Bone mineral density
Study 17896582 — Surrogate Endpoint (SUR): Bone mineral density
Study 9625684 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9625684 — Surrogate Endpoint (SUR): Blood pressure
Study 21762177 — Surrogate Endpoint (SUR): Blood pressure
Study 14651725 — Surrogate Endpoint (SUR): Blood pressure
Study 24214919 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 19173165 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7594128 — Surrogate Endpoint (SUR): Blood pressure
Study 29152243 — Surrogate Endpoint (SUR): Blood pressure
Study 31743054 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 31743054 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 31743054 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24119227 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 21208594 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 14982509 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9286851 — Surrogate Endpoint (SUR): Blood pressure
Study 29703724 — Surrogate Endpoint (SUR): Blood pressure
Study 20723593 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 20723593 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 20723593 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 12486426 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12486426 — Surrogate Endpoint (SUR): Blood pressure
Study 4904935 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26155923 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11345514 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 31535138 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 31535138 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21355143 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 19486853 — Surrogate Endpoint (SUR): Blood pressure
Study 16750465 — Surrogate Endpoint (SUR): Blood pressure
Study 9158883 — Surrogate Endpoint (SUR): Blood pressure
Study 25012498 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 25012498 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25012498 — Surrogate Endpoint (SUR): Blood pressure
Study 19776651 — Monitoring Biomarker (MOI): Procalcitonin
Study 18714171 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 1471304 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6148960 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 6148960 — Surrogate Endpoint (SUR): Blood pressure
Study 30374040 — Surrogate Endpoint (SUR): Blood pressure
Study 25305703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12855831 — Surrogate Endpoint (SUR): Blood pressure
Study 31261584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19178574 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 19178574 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 15642666 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 9387965 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7940137 — Surrogate Endpoint (SUR): Blood pressure
Study 24977750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24977750 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24977750 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24977750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18503141 — Surrogate Endpoint (SUR): Blood pressure
Study 1530166 — Surrogate Endpoint (SUR): Blood pressure
Study 31825472 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 19741581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31665314 — Surrogate Endpoint (SUR): Bone mineral density
Study 23812892 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20875810 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 20875810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6352035 — Surrogate Endpoint (SUR): Serum creatinine
Study 31727409 — Predictive Biomarker (PRD): Hormone receptor
Study 27499458 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24334573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24334573 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17094745 — Surrogate Endpoint (SUR): Serum creatinine
Study 9669391 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27418639 — Predictive Biomarker (PRD): ANXA5 mRNA
Genes: ANXA5; ANX5; ENX2; PP4
Study 23557429 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 19904567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11673746 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 26304969 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26304969 — Surrogate Endpoint (SUR): Blood pressure
Study 16174656 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11451177 — Monitoring Biomarker (MOI): HBV DNA
Study 18086001 — Predictive Biomarker (PRD): RALBP1 mRNA
Genes: RALBP1; RLIP; RLIP1; RLIP76
Study 15345733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15345733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15345733 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10209728 — Surrogate Endpoint (SUR): Blood pressure
Study 21310559 — Surrogate Endpoint (SUR): Blood pressure
Study 31020480 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 31020480 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26660491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26660491 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20118007 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15801938 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 12579599 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 12579599 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 31739840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31739840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31739840 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31739840 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31739840 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30400840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30400840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30400840 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 30400840 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 30400840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30400840 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30400840 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26371459 — Surrogate Endpoint (SUR): Blood pressure
Study 22076751 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22076751 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22076751 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 22076751 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28784181 — Surrogate Endpoint (SUR): Blood pressure
Study 26240230 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 21974695 — Surrogate Endpoint (SUR): Serum creatinine
Study 30646139 — Surrogate Endpoint (SUR): Blood pressure
Study 24074642 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8989238 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8989238 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24351700 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24351700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24351700 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19395425 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 14526714 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 10392679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10392679 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10392679 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24467828 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 24467828 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 24467828 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24467828 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 24467828 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22781788 — Surrogate Endpoint (SUR): Blood pressure
Study 22781788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22781788 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9573908 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study 7835776 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25152207 — Monitoring Biomarker (MOI): HBV DNA
Study 23084597 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 12491829 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9143391 — Safety Biomarker (SAF): Interleukin 1
Study 22031621 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22031621 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22031621 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26032952 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 22309242 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 22309242 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22309242 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 22309242 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 22309242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22309242 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 16116154 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 12169044 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10575337 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 23020162 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11669431 — Surrogate Endpoint (SUR): Blood pressure
Study 30136704 — Monitoring Biomarker (MOI): Procalcitonin
Study 30136704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30136704 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 30136704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30136704 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26968939 — Surrogate Endpoint (SUR): Blood pressure
Study 25623903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25623903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21107264 — Surrogate Endpoint (SUR): Blood pressure
Study 18363314 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 9641366 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 22071714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16980242 — Safety Biomarker (SAF): Hyaluronic acid
Study 16807617 — Surrogate Endpoint (SUR): Blood pressure
Study 9327314 — Surrogate Endpoint (SUR): Blood pressure
Study 3671896 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 18814906 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 16154017 — Surrogate Endpoint (SUR): Blood pressure
Study 27545697 — Surrogate Endpoint (SUR): Serum creatinine
Study 19145637 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19145637 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19145637 — Surrogate Endpoint (SUR): Blood pressure
Study 11266239 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9684804 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 2968595 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2968595 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31927581 — Surrogate Endpoint (SUR): Blood pressure
Study 27486817 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26832653 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16164393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2648788 — Surrogate Endpoint (SUR): Blood pressure
Study 26049551 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 26049551 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 23410616 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19485840 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 17595593 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17595593 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 17595593 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 9544873 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9544873 — Surrogate Endpoint (SUR): Blood pressure
Study 25852125 — Monitoring Biomarker (MOI): HBV DNA
Study 17644487 — Surrogate Endpoint (SUR): Blood pressure
Study 30925499 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 30925499 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 28539646 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25583749 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 25583749 — Predictive Biomarker (PRD): ABCC4 mRNA
Genes: ABCC4; MOATB; MRP4
Study 14982197 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14982197 — Surrogate Endpoint (SUR): Blood pressure
Study 3752983 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 25280957 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15760531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15760531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15760531 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 15760531 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18172652 — Surrogate Endpoint (SUR): Bone mineral density
Study 12519412 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol