TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04519580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02800265 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study NCT00435123 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01983462 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01983462 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04516343 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04539938 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02283268 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02682693 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT02682693 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04821180 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03301467 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT03841760 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01574053 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03876535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03876535 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT00607399 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01382498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01382498 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT04735783 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT00706771 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT02250768 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02820064 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT02820064 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT02697188 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT01615406 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT01615406 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04260945 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01558050 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04420806 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01817959 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT00923845 — Safety Biomarker (SAF): Th2 cell
Study NCT03687606 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study NCT02918357 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02484664 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT03244930 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03244930 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01831076 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02554617 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01859455 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03457974 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03457974 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study NCT03457974 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04136600 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00085449 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02439346 — Predictive Biomarker (PRD): MKNK1 mRNA
Genes: MKNK1; MNK1
Study NCT02994576 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02358863 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00439283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03993457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01117129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04689399 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01183065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02769143 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03362723 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT04815811 — Predictive Biomarker (PRD): IRAK1 mRNA
Genes: IRAK1; IRAK
Study NCT04815811 — Predictive Biomarker (PRD): IKBKG mRNA
Genes: IKBKG; FIP3; NEMO
Study NCT02134015 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02134015 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02134015 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT02134015 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study NCT02134015 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study NCT02134015 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03234712 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03234712 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03754868 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03754868 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT03754868 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT03870412 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05019586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT04334044 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study NCT04334044 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT04334044 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT04334044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04388072 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT05864937 — Safety Biomarker (SAF): MTHFR
Study NCT02358928 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03662646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01119261 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01119261 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT02522897 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02522897 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02066610 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04795505 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02346955 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study NCT03771222 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT03771222 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study NCT03771222 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04536285 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04338841 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01965171 — Predictive Biomarker (PRD): Liver iron
Study NCT00301561 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01776723 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT01776723 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00590525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02039531 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04011475 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT02084589 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02098343 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02329405 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study NCT02559830 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT02559830 — Predictive Biomarker (PRD): ARSA mRNA
Genes: ARSA
Study NCT02248584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00310687 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT04479306 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00229242 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03633266 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01271374 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01031108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01031108 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00638898 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04770701 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01427244 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04662437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04662437 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04439877 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00562991 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03588936 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01392209 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01392209 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03940118 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01183455 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00017173 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT03531203 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03531203 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03119285 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04697446 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT04101994 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study NCT04509206 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02530619 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT01648036 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00677768 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00677768 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01543035 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00946829 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00953654 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT04107207 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study NCT04107207 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03100175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03585686 — Predictive Biomarker (PRD): CD207 mRNA
Genes: CD207; CLEC4K
Study NCT02581098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT00923806 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00923806 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00923806 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02591394 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02239458 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02239458 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02021435 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01918371 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01918371 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00408642 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01082705 — Surrogate Endpoint (SUR): Hematologic response
Study NCT02352493 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT03590977 — Surrogate Endpoint (SUR): Bacterial count
Study NCT01805518 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01805518 — Safety Biomarker (SAF): BDNF
Study NCT00477711 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03495336 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03654768 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03654768 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03000764 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study NCT01670773 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT01776008 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT01776008 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01776008 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04262089 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study NCT00980759 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT03891212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03891212 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00006171 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00006171 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02427776 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02173587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00724633 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02284737 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03086954 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02664428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02664428 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03095417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03095417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03095417 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT03095417 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03095417 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02183792 — Surrogate Endpoint (SUR): Serum sodium
Study NCT00826683 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00924339 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT00924339 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00924339 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT00490074 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02667912 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02881515 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01063010 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01063010 — Predictive Biomarker (PRD): VEGF
Genes: VEGFA; VEGF-A; VPF
Study NCT01063010 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02549404 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT03821454 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03821454 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05433233 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02335593 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01413126 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT01413126 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT01413126 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03433196 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT06069453 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04544579 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03989362 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study NCT04558359 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01052194 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study NCT03028376 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT03028376 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT03803176 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT02251366 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02251366 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04344210 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02368158 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01805245 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04639986 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04639986 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04639986 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04568564 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02148978 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02148978 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04312542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04312542 — Surrogate Endpoint (SUR): Serum hemoglobin A1C
Study NCT04027530 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02926690 — Predictive Biomarker (PRD): MELK mRNA
Genes: MELK; KIAA0175
Study NCT00282607 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT03384316 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03384316 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT02642458 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03166189 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02418546 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02418546 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT02279303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02279303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03747029 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT03747029 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02237638 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02489669 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02770872 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03044704 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT03044704 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT02050984 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01568983 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01633476 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02719717 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03253653 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01095744 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01095744 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT00296140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study NCT03783559 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT04898088 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study NCT04898088 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA