TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02531347 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02914639 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01936571 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT01936571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01936571 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT01936571 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT01936571 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT01936571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01936571 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT01936571 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT02778893 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02061202 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01743079 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02244645 — Safety Biomarker (SAF): BDNF
Study NCT03812393 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01435083 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01722968 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03573414 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02612311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04199078 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02173548 — Safety Biomarker (SAF): Interleukin 1
Study NCT02813629 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02813629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02096406 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01087827 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01835717 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT03188159 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT05224115 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03618368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03618368 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study NCT02644486 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03480152 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT03480152 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT04693858 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study NCT01475435 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT01475435 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01856920 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02977000 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02977000 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00651664 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT02107833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03326388 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT02653131 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04002401 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00547404 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study NCT02706132 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02706132 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT04104620 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT04601389 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT04370470 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT03167333 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00701610 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT00701610 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT04647201 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT04647201 — Predictive Biomarker (PRD): PINK1 mRNA
Genes: PINK1
Study NCT02867735 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02644759 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03748966 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT04337424 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04178798 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT04178798 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00295256 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03221192 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT02390050 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04510662 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04510662 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT05035758 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04144140 — Predictive Biomarker (PRD): STING1 mRNA
Genes: STING1; ERIS; MITA; STING; TMEM173
Study NCT00614380 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01692899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02376764 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03647488 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03647488 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03647488 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04273334 — Predictive Biomarker (PRD): NEB mRNA
Genes: NEB
Study NCT00811811 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03745729 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT03745729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03745729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03206203 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT00589381 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT00665860 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02626130 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00392392 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00788307 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT03824041 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02981108 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02981108 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04561557 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03082040 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03207009 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04290936 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT04290936 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03356782 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT04918706 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03471351 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01048554 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00897312 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT04566003 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04279392 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01236365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00326833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02472964 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04276532 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT02947893 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02947893 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT02216708 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00285909 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT01393275 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01493843 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02156297 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02249546 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03742895 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT03948061 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01021449 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00795366 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT02507609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03554382 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02953522 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT02953522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01604629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03133208 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT03133208 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study NCT02476786 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04480840 — Predictive Biomarker (PRD): PLN mRNA
Genes: PLN; PLB
Study NCT02670577 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02670577 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02670577 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02488564 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01686334 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT04169789 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02140996 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT03470688 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02167308 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04403412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04403412 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02997787 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT02997787 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT00267085 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00267085 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02847247 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT01049295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01415531 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02518737 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00005695 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01459302 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01459302 — Pharmacodynamic Biomarker (PDY): Guanine nucleotide exchange factor C9orf72
Genes: C9orf72; DENND9; DENNL72
Study NCT00637065 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT00879866 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT02329470 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02329470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02329470 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00472225 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01383746 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT04356495 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03894020 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02358096 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01037348 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04572308 — Predictive Biomarker (PRD): CD7 mRNA
Genes: CD7
Study NCT03689023 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02285673 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03044613 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01092130 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01092130 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01092130 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT01338025 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00017121 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04077060 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT01160276 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT01514019 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study NCT01951586 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT01945866 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01945866 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04083976 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT03777943 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT02088450 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00419510 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03103126 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01248273 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT00887549 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT00103168 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT03459443 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT00805181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01794000 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00986973 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study NCT03433079 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04428073 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03046693 — Safety Biomarker (SAF): BDNF
Study NCT02314052 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT01912677 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00677404 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01154530 — Surrogate Endpoint (SUR): Bacterial count
Study NCT01454193 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01454193 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01771107 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT00636649 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study NCT00005933 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03659916 — Predictive Biomarker (PRD): ATP8B1 mRNA
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study NCT03431740 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT05121714 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT04547010 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01382472 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT01382472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02737085 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02689518 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01669252 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00367939 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01422421 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01422421 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02743273 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02650401 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT02650401 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT02704468 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT04487093 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02149758 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04133155 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT03063125 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00002674 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02508246 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study NCT03285802 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02034981 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00213512 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03510585 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT02035891 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05098678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00477321 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00477321 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study NCT00669890 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT04421183 — Predictive Biomarker (PRD): MUC17 mRNA
Genes: MUC17; MUC3
Study NCT01021735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02388581 — Predictive Biomarker (PRD): CYP2C18 mRNA
Genes: CYP2C18
Study NCT02388581 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04068896 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study NCT00526292 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04367350 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02137850 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT01704638 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT02597400 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study NCT03597815 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02428062 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01813916 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01365832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00136981 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT02215382 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00081497 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT01261572 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02119689 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT02119689 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01183260 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00080457 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03787056 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT00866177 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT04338685 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study NCT02987127 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT02987127 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT01970280 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT04027192 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02245477 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02245477 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01092741 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01092741 — Surrogate Endpoint (SUR): Hematologic response
Study NCT02641847 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT02611973 — Predictive Biomarker (PRD): HR mRNA
Genes: HR