TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24930728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24930728 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21697747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21697747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21697747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1657799 — Surrogate Endpoint (SUR): Blood pressure
Study 1657799 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7041943 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31603565 — Surrogate Endpoint (SUR): Probing pocket depth
Study 24975467 — Surrogate Endpoint (SUR): Serum testosterone
Study 16083704 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16083704 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 16083704 — Predictive Biomarker (PRD): ABCB4 mRNA
Genes: ABCB4; MDR3; PGY3
Study 16083704 — Predictive Biomarker (PRD): ABCC4 mRNA
Genes: ABCC4; MOATB; MRP4
Study 10347293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10347293 — Safety Biomarker (SAF): Interleukin 1
Study 24724887 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 24716637 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 15110095 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15110095 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 8056578 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26518955 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 14727011 — Surrogate Endpoint (SUR): Bone mineral density
Study 2970805 — Surrogate Endpoint (SUR): Blood pressure
Study 22968306 — Surrogate Endpoint (SUR): Blood pressure
Study 17161060 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17161060 — Surrogate Endpoint (SUR): Serum creatinine
Study 7576 — Surrogate Endpoint (SUR): Blood pressure
Study 26417835 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 26417835 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 21673660 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17183151 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 22539169 — Surrogate Endpoint (SUR): Blood pressure
Study 21285133 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21285133 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21285133 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19720808 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17927859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17927859 — Safety Biomarker (SAF): IL-6 and IL-10
Study 2850132 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2850132 — Surrogate Endpoint (SUR): Blood pressure
Study 24263123 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 14991636 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 9209198 — Surrogate Endpoint (SUR): Bone mineral density
Study 2831320 — Surrogate Endpoint (SUR): Blood pressure
Study 19548448 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 10093686 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26241349 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26241349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26241349 — Safety Biomarker (SAF): BDNF
Study 9492772 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30666827 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8275477 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 24131095 — Safety Biomarker (SAF): Hyaluronic acid
Study 22814178 — Surrogate Endpoint (SUR): Blood pressure
Study 20659545 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 20659545 — Surrogate Endpoint (SUR): Serum creatinine
Study 17980273 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 29236273 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 25481673 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21926663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21926663 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21926663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19953917 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19953917 — Surrogate Endpoint (SUR): Blood pressure
Study 15131684 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 9438892 — Surrogate Endpoint (SUR): Blood pressure
Study 27861157 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27861157 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15904635 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8158888 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8158888 — Safety Biomarker (SAF): 51Cr-EDTA
Study 17524938 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 11434169 — Predictive Biomarker (PRD): GAPDH mRNA
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 11434169 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 11434169 — Predictive Biomarker (PRD): REN mRNA
Genes: REN
Study 9596205 — Surrogate Endpoint (SUR): Blood pressure
Study 3241216 — Surrogate Endpoint (SUR): Blood pressure
Study 22972399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11571237 — Surrogate Endpoint (SUR): Blood pressure
Study 8112194 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23998657 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 19628217 — Predictive Biomarker (PRD): IL2RG mRNA
Genes: IL2RG
Study 19628217 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 19628217 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 19628217 — Predictive Biomarker (PRD): LIG4 mRNA
Genes: LIG4
Study 9322808 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22254230 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 29729672 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 10235220 — Monitoring Biomarker (MOI): HBV DNA
Study 31876460 — Surrogate Endpoint (SUR): Blood pressure
Study 22677260 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20129543 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27381968 — Surrogate Endpoint (SUR): Serum creatinine
Study 25881462 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 8432915 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24072136 — Surrogate Endpoint (SUR): Serum creatinine
Study 24072136 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24072136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21902684 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18239240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14709298 — Surrogate Endpoint (SUR): Blood pressure
Study 30470229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30470229 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27798770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27798770 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20610550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15718356 — Surrogate Endpoint (SUR): Bone mineral density
Study 10216805 — Surrogate Endpoint (SUR): Blood pressure
Study 2196146 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 24107881 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 8001520 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8363067 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8363067 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3539618 — Surrogate Endpoint (SUR): Blood pressure
Study 30120066 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 28318397 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 28318397 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26854974 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26854974 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22044044 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 22044044 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 19387424 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 19387424 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 1345132 — Surrogate Endpoint (SUR): Serum creatinine
Study 25042199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20189608 — Surrogate Endpoint (SUR): Serum creatinine
Study 20189608 — Surrogate Endpoint (SUR): Blood pressure
Study 20189608 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16230877 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16230877 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12967694 — Surrogate Endpoint (SUR): Blood pressure
Study 8706296 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8706296 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21900198 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19473629 — Safety Biomarker (SAF): Urinary total protein
Study 31155953 — Predictive Biomarker (PRD): HDAC6 mRNA
Genes: HDAC6; KIAA0901; JM21
Study 31155953 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 31155953 — Predictive Biomarker (PRD): AMACR mRNA
Genes: AMACR
Study 24585506 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24585506 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22211733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 11129341 — Predictive Biomarker (PRD): FAS mRNA
Genes: FAS; APT1; FAS1; TNFRSF6
Study 11129341 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8839875 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8839875 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 20127540 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17650793 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17650793 — Surrogate Endpoint (SUR): Serum creatinine
Study 2500070 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 28679471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28679471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28679471 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22964356 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11204290 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27358210 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 17589281 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17589281 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2592583 — Surrogate Endpoint (SUR): Blood pressure
Study 29804376 — Monitoring Biomarker (MOI): HBV DNA
Study 28245911 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28245911 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study 21498674 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19080708 — Surrogate Endpoint (SUR): Blood pressure
Study 1671884 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31825025 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 29576447 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 23235967 — Surrogate Endpoint (SUR): Serum creatinine
Study 20659762 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10615220 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26756278 — Predictive Biomarker (PRD): MAVS mRNA
Genes: MAVS; IPS1; KIAA1271; VISA
Study 24713402 — Safety Biomarker (SAF): Interleukin 1
Study 20109071 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 20109071 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 20109071 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 1303482 — Surrogate Endpoint (SUR): Blood pressure
Study 24403492 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24403492 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study 24403492 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 24403492 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24403492 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8750569 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28852318 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 23630307 — Surrogate Endpoint (SUR): Blood pressure
Study 9427885 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9427885 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3504725 — Surrogate Endpoint (SUR): Serum calcium
Study 29067749 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 16553274 — Predictive Biomarker (PRD): RP9 mRNA
Genes: RP9
Study 2481787 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2481787 — Surrogate Endpoint (SUR): Blood pressure
Study 25795285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22473395 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 15111524 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15111524 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30264480 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28886437 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28886437 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 20809859 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 19298319 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 1703237 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 18046434 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18046434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18046434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26888112 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 26888112 — Predictive Biomarker (PRD): ADRB3 mRNA
Genes: ADRB3; ADRB3R; B3AR
Study 21037456 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21037456 — Surrogate Endpoint (SUR): Blood pressure
Study 17882161 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 17882161 — Predictive Biomarker (PRD): REEP5 mRNA
Genes: REEP5; C5orf18; DP1; TB2
Study 24290781 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17129220 — Surrogate Endpoint (SUR): Blood pressure
Study 20191820 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 12525736 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 10978246 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10978246 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8421798 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16184544 — Surrogate Endpoint (SUR): Serum creatinine
Study 25190617 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 19464001 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 7953888 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29154814 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29154814 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29154814 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2212394 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 346042 — Predictive Biomarker (PRD): EMP2 mRNA
Genes: EMP2; XMP
Study 28146397 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study 24355450 — Surrogate Endpoint (SUR): Blood pressure
Study 19204412 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 19204412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19204412 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8133020 — Surrogate Endpoint (SUR): Blood pressure
Study 21629200 — Predictive Biomarker (PRD): CARS1 mRNA
Genes: CARS1; CARS
Study 17723076 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9702445 — Surrogate Endpoint (SUR): Blood pressure
Study 25259546 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25259546 — Surrogate Endpoint (SUR): Blood pressure
Study 29462733 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29462733 — Safety Biomarker (SAF): BDNF
Study 29462733 — Surrogate Endpoint (SUR): Serum creatinine
Study 30007544 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 16364860 — Surrogate Endpoint (SUR): Serum creatinine
Study 7482648 — Surrogate Endpoint (SUR): Blood pressure
Study 30276532 — Predictive Biomarker (PRD): PHC1 mRNA
Genes: PHC1; EDR1; PH1
Study 24976429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24976429 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17950791 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 14769724 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10714084 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1389192 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24286801 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 24286801 — Safety Biomarker (SAF): Hyaluronic acid
Study 18641189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18641189 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18641189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18641189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8848258 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 1411403 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 1411403 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 3318897 — Surrogate Endpoint (SUR): Blood pressure
Study 26735552 — Surrogate Endpoint (SUR): Blood pressure
Study 10487482 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1762811 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14749760 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 10604327 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26024304 — Predictive Biomarker (PRD): PSMD6 mRNA
Genes: PSMD6; KIAA0107; PFAAP4
Study 21080920 — Safety Biomarker (SAF): Hyaluronic acid
Study 31757216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29771807 — Surrogate Endpoint (SUR): Serum sodium
Study 9098588 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29962178 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20634355 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16177596 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 1991923 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6109741 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31148196 — Monitoring Biomarker (MOI): miR-92a-3p
Study 21931035 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9215300 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2223687 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24256373 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 17156104 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9120502 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18773755 — Surrogate Endpoint (SUR): Blood pressure
Study 16162814 — Surrogate Endpoint (SUR): Serum creatinine
Study 10087737 — Surrogate Endpoint (SUR): Blood pressure
Study 1683682 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6982989 — Surrogate Endpoint (SUR): Blood pressure
Study 31894038 — Monitoring Biomarker (MOI): Procalcitonin