TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03250702 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01856751 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT02062307 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01860456 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01860456 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT01860456 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT01860456 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study NCT04134247 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00870363 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01613781 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study NCT01959542 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT02286934 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01301872 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT02908685 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT03948373 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00588445 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00588445 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00005169 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03666507 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02061969 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01761318 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00898924 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00898924 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04539522 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02671539 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study NCT01571661 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00479908 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02979613 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02209948 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT02416427 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study NCT02416427 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT03846882 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study NCT01485900 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01485900 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04355533 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01814501 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01814501 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT04339400 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT02559869 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT04033159 — Predictive Biomarker (PRD): DNM2 mRNA
Genes: DNM2; DYN2
Study NCT04033159 — Predictive Biomarker (PRD): MTM1 mRNA
Genes: MTM1; CG2
Study NCT02156089 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02983071 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02983071 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02877628 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT02877628 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT04134000 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04601051 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT03619109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01452139 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01452139 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT03838991 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study NCT00570583 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT00570583 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT00570583 — Predictive Biomarker (PRD): TPH2 mRNA
Genes: TPH2; NTPH
Study NCT00570583 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study NCT02644707 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT02667483 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03114137 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03224650 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00003294 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT01504633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01555359 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02244580 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02244580 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02244580 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT00188851 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03538184 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03538184 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study NCT03538184 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03538184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT03538184 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01317186 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02038595 — Predictive Biomarker (PRD): NE
Study NCT03824275 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03032614 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT01669421 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT02094001 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT05058521 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00457938 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT03517709 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01466699 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01163773 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01813721 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04124107 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04082988 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT02112825 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02769702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02699450 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02699450 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02177643 — Safety Biomarker (SAF): Interleukin 1
Study NCT03334279 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT00355342 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02688582 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03829046 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT04334499 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT04568122 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01243346 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT02838277 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study NCT03712033 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01572038 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00489853 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01437007 — Predictive Biomarker (PRD): PLK1 mRNA
Genes: PLK1; PLK
Study NCT00438854 — Predictive Biomarker (PRD): LYN mRNA
Genes: LYN; JTK8
Study NCT00046163 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01556776 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT00554398 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT03033017 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01879566 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03504241 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03100812 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01223898 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01223898 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03207945 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03481712 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03155009 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01468766 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT01468766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01468766 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02935465 — Predictive Biomarker (PRD): CNBP mRNA
Genes: CNBP; RNF163; ZNF9
Study NCT03693963 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03848845 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04111094 — Predictive Biomarker (PRD): DKK3 mRNA
Genes: DKK3; REIC; UNQ258/PRO295
Study NCT02584504 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02584504 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02584504 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03890679 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study NCT02242838 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00017134 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT00283439 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT02047799 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02965443 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02965443 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00941083 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT04143165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02850536 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04155515 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04174300 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study NCT02822378 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01289769 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02614807 — Surrogate Endpoint (SUR): Serum sodium
Study NCT00423891 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02821377 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT02821377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00202618 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00639834 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03690388 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02984358 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03464903 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02632201 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02632201 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02372708 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02442453 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT02442453 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT06267235 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT04547062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01757223 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00907374 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00993109 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02736656 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study NCT01262014 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT04209179 — Surrogate Endpoint (SUR): Serum calcium
Study NCT04224272 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04224272 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04224272 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01026051 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study NCT00872846 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01882517 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT05516784 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03751410 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03751410 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03886558 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03958656 — Predictive Biomarker (PRD): SLAMF7 mRNA
Genes: SLAMF7; CS1; UNQ576/PRO1138
Study NCT03958656 — Predictive Biomarker (PRD): F7 mRNA
Genes: F7
Study NCT03984149 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study NCT03984149 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study NCT03984149 — Predictive Biomarker (PRD): LIPA mRNA
Genes: LIPA
Study NCT03984149 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03856762 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03599817 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03599817 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00159913 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00533065 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT03488212 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01787578 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT02319538 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT01482767 — Predictive Biomarker (PRD): BOC mRNA
Genes: BOC; UNQ604/PRO1190
Study NCT02823184 — Predictive Biomarker (PRD): XBP1 mRNA
Genes: XBP1; TREB5; XBP2
Study NCT02387164 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00028431 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT00028431 — Safety Biomarker (SAF): Interleukin 12
Study NCT04333953 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01867593 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01358617 — Predictive Biomarker (PRD): UCHL1 mRNA
Genes: UCHL1
Study NCT02617550 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04212468 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05854875 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT04174313 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00900146 — Safety Biomarker (SAF): Interleukin 1
Study NCT03425721 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT05215015 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT03195959 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04952038 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03164083 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04222738 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02864173 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02864173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00001625 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02259153 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05730647 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05730647 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03503292 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01540409 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00637325 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00043823 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00043823 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03182595 — Predictive Biomarker (PRD): SULT1A1 mRNA
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study NCT01887119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03451877 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study NCT03451877 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT04642924 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03146234 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT00743912 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03810066 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04498793 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00726570 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00002882 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02042924 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT02761577 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT02761577 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00229580 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT03001570 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03001570 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02103374 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study NCT02633956 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04565054 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04565054 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02714361 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT02727348 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03455868 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03755141 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03211026 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01768156 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT01400295 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02868450 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study NCT00162461 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT04312607 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02408354 — Predictive Biomarker (PRD): ATP1A3 mRNA
Genes: ATP1A3
Study NCT02763475 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT06074107 — Predictive Biomarker (PRD): TP53INP2 mRNA
Genes: TP53INP2; C20orf110; DOR; PINH
Study NCT02639481 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT02435680 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00262548 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00262548 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01996267 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04391595 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03640637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03012997 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04382911 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT04382911 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00361699 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00673023 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT00523835 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00554619 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02088073 — Surrogate Endpoint (SUR): Serum potassium
Study NCT04211337 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT02615951 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01946399 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03057028 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00925483 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00367172 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02022228 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study NCT01933906 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01933906 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03139890 — Surrogate Endpoint (SUR): Blood pressure