TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31955525 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31290518 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 25820243 — Surrogate Endpoint (SUR): Blood pressure
Study 22669291 — Predictive Biomarker (PRD): UGT2B17 mRNA
Genes: UGT2B17
Study 31856912 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31856912 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 27033552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27033552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27033552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31238011 — Surrogate Endpoint (SUR): Blood pressure
Study 31238011 — Surrogate Endpoint (SUR): Serum sodium
Study 16305726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16305726 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16305726 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16305726 — Safety Biomarker (SAF): Interleukin 1
Study 16305726 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16305726 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 16305726 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 16305726 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16305726 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 183943 — Surrogate Endpoint (SUR): Blood pressure
Study 183943 — Surrogate Endpoint (SUR): Serum potassium
Study 29392960 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29392960 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23890196 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16037180 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16037180 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 16037180 — Surrogate Endpoint (SUR): Blood pressure
Study 28857909 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 27820648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16125525 — Safety Biomarker (SAF): Reactive oxygen species
Study 12163783 — Surrogate Endpoint (SUR): Serum creatinine
Study 8951506 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 30394494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30394494 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30394494 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22984171 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 22113535 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22113535 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20017910 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24172937 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 20212251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 12269651 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9470082 — Surrogate Endpoint (SUR): Blood pressure
Study 11728078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21493664 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21493664 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 21493664 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7608317 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1978736 — Surrogate Endpoint (SUR): Blood pressure
Study 328540 — Surrogate Endpoint (SUR): Serum potassium
Study 25656133 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24531742 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 19716598 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15143717 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9043726 — Surrogate Endpoint (SUR): Blood pressure
Study 14626183 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 8962554 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14621717 — Surrogate Endpoint (SUR): Serum creatinine
Study 24686255 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 19443679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19443679 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19443679 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19443679 — Surrogate Endpoint (SUR): Blood pressure
Study 7585287 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 7585287 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24933106 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22684355 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22684355 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8195678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8195678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28986606 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 12483729 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 21350025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14767029 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14767029 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 14767029 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 9602958 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26114996 — Surrogate Endpoint (SUR): Blood pressure
Study 9029036 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31420748 — Surrogate Endpoint (SUR): Bone mineral density
Study 16139450 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16139450 — Surrogate Endpoint (SUR): Bone mineral density
Study 26386732 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 26386732 — Surrogate Endpoint (SUR): Blood pressure
Study 21981842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14666012 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9117888 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3025246 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3025246 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 28296588 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28296588 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18339027 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 14612213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14612213 — Safety Biomarker (SAF): Interleukin 1
Study 14612213 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14612213 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19535430 — Surrogate Endpoint (SUR): Blood pressure
Study 8838483 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26685010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10412878 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10412878 — Surrogate Endpoint (SUR): Blood pressure
Study 30952509 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19787222 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12439083 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 8746642 — Surrogate Endpoint (SUR): Blood pressure
Study 29800372 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 29800372 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 29800372 — Surrogate Endpoint (SUR): Bone mineral density
Study 12510801 — Surrogate Endpoint (SUR): Bone mineral density
Study 15774170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16005883 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16005883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11725155 — Surrogate Endpoint (SUR): Blood pressure
Study 27228512 — Surrogate Endpoint (SUR): Blood pressure
Study 18953651 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8707387 — Surrogate Endpoint (SUR): Blood pressure
Study 1746418 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30694523 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 26497831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26497831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21765368 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 17342038 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9700954 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9700954 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 2528737 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 2528737 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 24512796 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 19841526 — Surrogate Endpoint (SUR): Serum creatinine
Study 8017316 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 29423177 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 26315154 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 23137103 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21450602 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21450602 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30365255 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30365255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25742759 — Surrogate Endpoint (SUR): Serum creatinine
Study 20622687 — Surrogate Endpoint (SUR): Blood pressure
Study 16874784 — Surrogate Endpoint (SUR): Bone mineral density
Study 3896716 — Surrogate Endpoint (SUR): Serum calcium
Study 3896716 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22781566 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20424219 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20424219 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 15939243 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20884622 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 20884622 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 20884622 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 10648338 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22989898 — Surrogate Endpoint (SUR): Blood pressure
Study 12296423 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9839589 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8009976 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18805154 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29402270 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26253255 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16002915 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20714166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11411817 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 8021335 — Surrogate Endpoint (SUR): Blood pressure
Study 20615632 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10880791 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 1712282 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 19387363 — Surrogate Endpoint (SUR): Blood pressure
Study 15144935 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26660000 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study 20339195 — Surrogate Endpoint (SUR): Blood pressure
Study 15882256 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30968546 — Surrogate Endpoint (SUR): Blood pressure
Study 28077221 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 3315265 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 29036504 — Surrogate Endpoint (SUR): Blood pressure
Study 18000088 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 16184062 — Surrogate Endpoint (SUR): Blood pressure
Study 28382811 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 21296248 — Surrogate Endpoint (SUR): Blood pressure
Study 17074346 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21234852 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18259123 — Surrogate Endpoint (SUR): Blood pressure
Study 9187779 — Surrogate Endpoint (SUR): Blood pressure
Study 31744458 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 29193767 — Surrogate Endpoint (SUR): Blood pressure
Study 29193767 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27999018 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26310984 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20456906 — Surrogate Endpoint (SUR): Blood pressure
Study 16904092 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15146409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10467196 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 23725301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23725301 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23725301 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 15458016 — Surrogate Endpoint (SUR): Blood pressure
Study 11442735 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8070610 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8070610 — Surrogate Endpoint (SUR): Blood pressure
Study 27864832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27864832 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21791965 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 23832575 — Surrogate Endpoint (SUR): Bone mineral density
Study 16036509 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 24632042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24632042 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15155114 — Surrogate Endpoint (SUR): Bone mineral density
Study 28124444 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 23826742 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22452928 — Predictive Biomarker (PRD): ITGAL mRNA
Genes: ITGAL; CD11A
Study 22452928 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22452928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22452928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22452928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22452928 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 22452928 — Predictive Biomarker (PRD): OGG1 mRNA
Genes: OGG1; MMH; MUTM; OGH1
Study 22452928 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16223392 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16223392 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 16223392 — Surrogate Endpoint (SUR): Blood pressure
Study 12139219 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25565364 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21775681 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 17542980 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 23056361 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 18626028 — Surrogate Endpoint (SUR): Blood pressure
Study 11938824 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 11938824 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 11938824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11938824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8957976 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19324976 — Surrogate Endpoint (SUR): Bone mineral density
Study 14961167 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 11865133 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 2194280 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2194280 — Surrogate Endpoint (SUR): Blood pressure
Study 15277911 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 7886584 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30845949 — Surrogate Endpoint (SUR): Blood pressure
Study 22139679 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3432173 — Surrogate Endpoint (SUR): Blood pressure
Study 9567231 — Surrogate Endpoint (SUR): Blood pressure
Study 28598202 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21609410 — Surrogate Endpoint (SUR): Blood pressure
Study 11576768 — Predictive Biomarker (PRD): RHOF mRNA
Genes: RHOF; ARHF; RIF
Study 7093115 — Surrogate Endpoint (SUR): Blood pressure
Study 29040598 — Surrogate Endpoint (SUR): Blood pressure
Study 25979364 — Surrogate Endpoint (SUR): Blood pressure
Study 23173821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16902069 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16902069 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16902069 — Surrogate Endpoint (SUR): Blood pressure
Study 14747646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11505349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3531560 — Surrogate Endpoint (SUR): Blood pressure
Study 21733268 — Surrogate Endpoint (SUR): Blood pressure
Study 11428734 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2454254 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 2454254 — Surrogate Endpoint (SUR): Blood pressure
Study 2454254 — Surrogate Endpoint (SUR): Serum potassium
Study 22945298 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 28542447 — Predictive Biomarker (PRD): NR2F1 mRNA
Genes: NR2F1; EAR3; ERBAL3; TFCOUP1
Study 28542447 — Predictive Biomarker (PRD): MSI1 mRNA
Genes: MSI1
Study 28542447 — Predictive Biomarker (PRD): MYH1 mRNA
Genes: MYH1
Study 28542447 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 28542447 — Predictive Biomarker (PRD): KHDRBS3 mRNA
Genes: KHDRBS3; SALP; SLM2
Study 28542447 — Predictive Biomarker (PRD): NFKBIE mRNA
Genes: NFKBIE; IKBE
Study 28542447 — Predictive Biomarker (PRD): LYZ mRNA
Genes: LYZ; LZM
Study 28542447 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 28542447 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 25939711 — Predictive Biomarker (PRD): POU2F1 mRNA
Genes: POU2F1; OCT1; OTF1
Study 21737373 — Predictive Biomarker (PRD): CD58 mRNA
Genes: CD58; LFA3
Study 15456674 — Surrogate Endpoint (SUR): Blood pressure
Study 23222369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10872566 — Surrogate Endpoint (SUR): Blood pressure
Study 24375941 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 19775763 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10580024 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 6371293 — Predictive Biomarker (PRD): TOB1 mRNA
Genes: TOB1; TOB; TROB1