TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03166904 — Predictive Biomarker (PRD): RICTOR mRNA
Genes: RICTOR; KIAA1999
Study NCT00271973 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00331565 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00331565 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT00216060 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02404558 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02404558 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02712294 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03239145 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study NCT03944434 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03944434 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00879684 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study NCT03856697 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01021072 — Safety Biomarker (SAF): Interleukin 1
Study NCT04502667 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01204944 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT01460030 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01460030 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study NCT01460030 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT00310492 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00002592 — Predictive Biomarker (PRD): MYB mRNA
Genes: MYB
Study NCT00998478 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02733133 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02103101 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT00002730 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01995968 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT02810743 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04223596 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study NCT04223596 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03641976 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01764386 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01764386 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01764386 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01426815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02833896 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02833896 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02833896 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02833896 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT02990728 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02990728 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04327336 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01148225 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03062176 — Safety Biomarker (SAF): Interleukin 1
Study NCT04559841 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT02111109 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02341118 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02341118 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04506567 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02644538 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03756779 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT04453969 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02079363 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT01465568 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05724212 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05724212 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04423003 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00541710 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01785615 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01785615 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03782662 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03782662 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03798444 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00357955 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02891213 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT01205282 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT03605992 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04636008 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT03644043 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT01020617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01020617 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01020617 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT01833169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03004157 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00052520 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT01985724 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01987934 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT01239004 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00669435 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT04591639 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT01738945 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02334943 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03206151 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06400238 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT01169519 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00852475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03764124 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04666753 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04666753 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT01272076 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT03372317 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01937689 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02361736 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT02361736 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT02611882 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01570777 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03711721 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00236054 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01251952 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02500927 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03553862 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03553862 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00376740 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05167617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03936894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03936894 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03936894 — Safety Biomarker (SAF): Interleukin 1
Study NCT00037999 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02185963 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00050076 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT01712568 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04779424 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02444442 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02948062 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study NCT01706809 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02531490 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00230035 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04125069 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04125069 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study NCT04125069 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT04125069 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04125069 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT03904823 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03904823 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01026415 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT01026415 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03096119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00816582 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT04334850 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03609333 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04268160 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01418235 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study NCT01418235 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01085890 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00939523 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02327325 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT00907205 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00365729 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01184300 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04065490 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02196467 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00709137 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03173300 — Predictive Biomarker (PRD): PMM2 mRNA
Genes: PMM2
Study NCT03008941 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01573819 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00787605 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00515216 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT00039403 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study NCT01711567 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02627274 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT02627274 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00683592 — Predictive Biomarker (PRD): F2R mRNA
Genes: F2R; CF2R; PAR1; TR
Study NCT02022358 — Surrogate Endpoint (SUR): Plasma methotrexate
Study NCT04194151 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04190927 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02888795 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04700319 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03614455 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03104335 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00602901 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT00498537 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00498537 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01783457 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00607516 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02534844 — Predictive Biomarker (PRD): NPC1 mRNA
Genes: NPC1
Study NCT02750657 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT02350361 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02350361 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03168906 — Surrogate Endpoint (SUR): Hematologic response
Study NCT00365131 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04108962 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT03267654 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03267654 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00008398 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02390297 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02390297 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00875082 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT00875082 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study NCT03677076 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT00368082 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study NCT00001239 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05701124 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05701124 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03675893 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02183376 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00061126 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02413788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02413788 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT00748787 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06120361 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT06120361 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT01681862 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04659668 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03860740 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03860740 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03860740 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT03860740 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03860740 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04087096 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03424239 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03023137 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT03109106 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03132311 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00003615 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01170715 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT03661554 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT02870439 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02870439 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT03881683 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT03025451 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03563638 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study NCT04162327 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02597049 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04733508 — Predictive Biomarker (PRD): GLP1R mRNA
Genes: GLP1R
Study NCT01499160 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00831987 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study NCT02036060 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study NCT00173212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00173212 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT02297230 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00107016 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00107016 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03717194 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03717194 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT03717194 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00001512 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03337516 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study NCT03337516 — Safety Biomarker (SAF): CDA
Genes: CDD
Study NCT04267978 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04267978 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04326933 — Surrogate Endpoint (SUR): Hematologic response
Study NCT05306990 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01643434 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01643434 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02926937 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03712280 — Surrogate Endpoint (SUR): Plasma ammonia
Study NCT01116219 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00774241 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03161353 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00389740 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00171249 — Surrogate Endpoint (SUR): Hematologic response
Study NCT04084990 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study NCT02129062 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03394833 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00136773 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02385786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02101879 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02101879 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT02101879 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00846898 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02125006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02125006 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT02125006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02125006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01358253 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00460850 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00808158 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03129061 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03874026 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03874026 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03874026 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT03874026 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04635878 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT00725764 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00725764 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT00725764 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00725764 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00725764 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01928615 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01500005 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01186016 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT03613584 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF