TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17213873 — Surrogate Endpoint (SUR): Serum creatinine
Study 105656 — Surrogate Endpoint (SUR): Serum potassium
Study 26880570 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 10585387 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7538555 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27977473 — Surrogate Endpoint (SUR): Blood pressure
Study 17222848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29941520 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 29941520 — Surrogate Endpoint (SUR): Blood pressure
Study 29941520 — Surrogate Endpoint (SUR): Serum sodium
Study 29941520 — Surrogate Endpoint (SUR): Serum potassium
Study 25033919 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 20728565 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 31900148 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 3813189 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23041092 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 23041092 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21474219 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 17947225 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15106359 — Surrogate Endpoint (SUR): Bone mineral density
Study 18426457 — Surrogate Endpoint (SUR): Blood pressure
Study 12634260 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 11388815 — Surrogate Endpoint (SUR): Blood pressure
Study 9252945 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3326920 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3326920 — Surrogate Endpoint (SUR): Blood pressure
Study 31683617 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 25799208 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21235822 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15205083 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25986600 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 25986600 — Predictive Biomarker (PRD): CYP2J2 mRNA
Genes: CYP2J2
Study 25986600 — Predictive Biomarker (PRD): EPHX2 mRNA
Genes: EPHX2
Study 19228414 — Surrogate Endpoint (SUR): Blood pressure
Study 9203932 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7869908 — Surrogate Endpoint (SUR): Blood pressure
Study 7869908 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 367576 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 31629881 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28089917 — Predictive Biomarker (PRD): DICER1 mRNA
Genes: DICER1; DICER; HERNA; KIAA0928
Study 28089917 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 28089917 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 22785005 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12153960 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 12153960 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12153960 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30207807 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 1546861 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 1546861 — Surrogate Endpoint (SUR): Serum creatinine
Study 16827248 — Surrogate Endpoint (SUR): Blood pressure
Study 11106211 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21799442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21799442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27329547 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 23106931 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 31679946 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 23375165 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8362600 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27849566 — Surrogate Endpoint (SUR): Blood pressure
Study 27849566 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27849566 — Surrogate Endpoint (SUR): Serum sodium
Study 21227601 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 16480471 — Surrogate Endpoint (SUR): Blood pressure
Study 8237748 — Surrogate Endpoint (SUR): Blood pressure
Study 29033381 — Surrogate Endpoint (SUR): Bone mineral density
Study 17655686 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28925467 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21546500 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20214327 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20214327 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2657428 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21867540 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 11325088 — Surrogate Endpoint (SUR): Serum creatinine
Study 29903120 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22776750 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22776750 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 8576819 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 2663800 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26568588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23223314 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 11687611 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10423615 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8175218 — Surrogate Endpoint (SUR): Blood pressure
Study 30172948 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30172948 — Surrogate Endpoint (SUR): Blood pressure
Study 24193868 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 23879079 — Surrogate Endpoint (SUR): Serum calcium
Study 18065810 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 18065810 — Surrogate Endpoint (SUR): Serum creatinine
Study 16427266 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14688490 — Surrogate Endpoint (SUR): Blood pressure
Study 3707675 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29266564 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 18279468 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 18279468 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18279468 — Predictive Biomarker (PRD): AGTR1 mRNA
Genes: AGTR1; AGTR1A; AGTR1B; AT2R1; AT2R1B
Study 18279468 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 18279468 — Predictive Biomarker (PRD): BDKRB2 mRNA
Genes: BDKRB2; BKR2
Study 11372005 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 3687360 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21097793 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 3436157 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27317442 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25256183 — Surrogate Endpoint (SUR): Blood pressure
Study 11521797 — Surrogate Endpoint (SUR): Pathological complete response
Study 9846284 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8279372 — Surrogate Endpoint (SUR): Blood pressure
Study 18576337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18576337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27004617 — Surrogate Endpoint (SUR): Blood pressure
Study 11712808 — Predictive Biomarker (PRD): UBC mRNA
Genes: UBC
Study 11712808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9222938 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9222938 — Surrogate Endpoint (SUR): Blood pressure
Study 8381164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 19321581 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 11318080 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22554294 — Predictive Biomarker (PRD): CLIC1 mRNA
Genes: CLIC1; G6; NCC27
Study 18053320 — Surrogate Endpoint (SUR): Blood pressure
Study 12571543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1458072 — Surrogate Endpoint (SUR): Serum creatinine
Study 31641322 — Surrogate Endpoint (SUR): Blood pressure
Study 24793078 — Predictive Biomarker (PRD): ALKBH1 mRNA
Genes: ALKBH1; ABH; ABH1; ALKBH
Study 18574656 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 24401815 — Surrogate Endpoint (SUR): Blood pressure
Study 18191112 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 15696076 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15696076 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8542158 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24705587 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 24705587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15638899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15638899 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8489308 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8489308 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 16630553 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 16630553 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15012730 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21887804 — Surrogate Endpoint (SUR): Blood pressure
Study 18021136 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 11191041 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11191041 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10780258 — Surrogate Endpoint (SUR): Blood pressure
Study 7828296 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7828296 — Surrogate Endpoint (SUR): Blood pressure
Study 2240382 — Surrogate Endpoint (SUR): Blood pressure
Study 29083219 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 19821969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11743506 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8168332 — Surrogate Endpoint (SUR): Blood pressure
Study 1546065 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 29886815 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 29886815 — Surrogate Endpoint (SUR): Bone mineral density
Study 23288914 — Surrogate Endpoint (SUR): Blood pressure
Study 16626573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16626573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30129666 — Surrogate Endpoint (SUR): Blood pressure
Study 23527347 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 9266623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17762286 — Safety Biomarker (SAF): Interleukin 1
Study 11865274 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 8786245 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2079571 — Monitoring Biomarker (MOI): HBV DNA
Study 31082269 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9507512 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31289983 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27856633 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20731006 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12094254 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12094254 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 12094254 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26460886 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 19546252 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 14682411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1622739 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 1622739 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1622739 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1622739 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30805949 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 28528859 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23458037 — Surrogate Endpoint (SUR): Blood pressure
Study 11345755 — Surrogate Endpoint (SUR): Blood pressure
Study 31779791 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22782463 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18948612 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18948612 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10967612 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8864962 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6084139 — Surrogate Endpoint (SUR): Blood pressure
Study 6084139 — Surrogate Endpoint (SUR): Serum uric acid
Study 27300579 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22672148 — Surrogate Endpoint (SUR): Blood pressure
Study 7540965 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 762813 — Surrogate Endpoint (SUR): Blood pressure
Study 23986780 — Surrogate Endpoint (SUR): Blood pressure
Study 21845243 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 7933838 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 10769276 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 28302952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16875647 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3318455 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3318455 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3318455 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 29934374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7588456 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7588456 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7588456 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2121394 — Surrogate Endpoint (SUR): Serum testosterone
Study 582772 — Surrogate Endpoint (SUR): Blood pressure
Study 27810347 — Surrogate Endpoint (SUR): Blood pressure
Study 23299013 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8288160 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8288160 — Surrogate Endpoint (SUR): Blood pressure
Study 27863277 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 27863277 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 27863277 — Predictive Biomarker (PRD): IGFBP1 mRNA
Genes: IGFBP1; IBP1
Study 24332524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24332524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24332524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24332524 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18315510 — Surrogate Endpoint (SUR): Blood pressure
Study 12362231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10399995 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8991841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12427056 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9112275 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 1742583 — Surrogate Endpoint (SUR): Bone mineral density
Study 7038189 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 28251822 — Surrogate Endpoint (SUR): Serum sodium
Study 20412274 — Surrogate Endpoint (SUR): Blood pressure
Study 9627917 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23179024 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 21349479 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21349479 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10971327 — Surrogate Endpoint (SUR): Bacterial count
Study 20605871 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17433950 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26578308 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 18438407 — Predictive Biomarker (PRD): MRPS30 mRNA
Genes: MRPS30; PDCD9; BM-047
Study 18438407 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 18438407 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15774846 — Predictive Biomarker (PRD): SCGB1A1 mRNA
Genes: SCGB1A1; CC10; CCSP; UGB
Study 1975995 — Surrogate Endpoint (SUR): Blood pressure
Study 23624336 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 20859301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20859301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20859301 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28155101 — Surrogate Endpoint (SUR): Blood pressure
Study 26848765 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 26848765 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17008798 — Surrogate Endpoint (SUR): Blood pressure
Study 16120091 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9451475 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9451475 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28600309 — Surrogate Endpoint (SUR): Blood pressure
Study 26749228 — Surrogate Endpoint (SUR): Blood pressure
Study 19366978 — Surrogate Endpoint (SUR): Blood pressure
Study 8431048 — Safety Biomarker (SAF): Interleukin 1
Study 8431048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8431048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30671061 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 30671061 — Predictive Biomarker (PRD): CD300LF mRNA
Genes: CD300LF; CD300F; CLM1; IGSF13; IREM1; NKIR; UNQ3105/PRO10111
Study 26466937 — Surrogate Endpoint (SUR): Bone mineral density
Study 19908105 — Surrogate Endpoint (SUR): Blood pressure
Study 10376571 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31011758 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19093205 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17893038 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 15108115 — Surrogate Endpoint (SUR): Blood pressure
Study 11672828 — Safety Biomarker (SAF): Interleukin 12
Study 11672828 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11672828 — Monitoring Biomarker (MOI): HBV DNA
Study 28632487 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 25580869 — Surrogate Endpoint (SUR): Blood pressure
Study 16500336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16500336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8968014 — Surrogate Endpoint (SUR): Blood pressure
Study 29901417 — Predictive Biomarker (PRD): SIRT6 mRNA
Genes: SIRT6; SIR2L6
Study 26335787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26335787 — Safety Biomarker (SAF): Interleukin 12
Study 26335787 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 16796157 — Surrogate Endpoint (SUR): Serum sodium
Study 8471122 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 29859385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1