TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11111813 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 11111813 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24622426 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 24622426 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24622426 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18236300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7971477 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27402560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 749854 — Predictive Biomarker (PRD): CBX1 mRNA
Genes: CBX1; CBX
Study 26611120 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22094449 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 19539099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19539099 — Surrogate Endpoint (SUR): Blood pressure
Study 16432050 — Surrogate Endpoint (SUR): Blood pressure
Study 9158080 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 31634178 — Surrogate Endpoint (SUR): Pathological complete response
Study 22706623 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 19169336 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6369883 — Surrogate Endpoint (SUR): Blood pressure
Study 6369883 — Surrogate Endpoint (SUR): Serum potassium
Study 29343012 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30525226 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 30525226 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 30525226 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 27809345 — Surrogate Endpoint (SUR): Blood pressure
Study 21914365 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20456838 — Surrogate Endpoint (SUR): Blood pressure
Study 20456838 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17157857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11789243 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1734794 — Surrogate Endpoint (SUR): Blood pressure
Study 20547017 — Surrogate Endpoint (SUR): Bone mineral density
Study 15531566 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 15531566 — Surrogate Endpoint (SUR): Blood pressure
Study 17311305 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 17311305 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 7921429 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25499302 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23446962 — Surrogate Endpoint (SUR): Blood pressure
Study 11464255 — Surrogate Endpoint (SUR): Blood pressure
Study 22781642 — Surrogate Endpoint (SUR): Pathological complete response
Study 2434802 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 2434802 — Surrogate Endpoint (SUR): Blood pressure
Study 30963205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15577135 — Surrogate Endpoint (SUR): Bone mineral density
Study 15577135 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2888736 — Surrogate Endpoint (SUR): Blood pressure
Study 22565005 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22565005 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12128107 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30663593 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 29448072 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29448072 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 10830255 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1727807 — Predictive Biomarker (PRD): RAB8A mRNA
Genes: RAB8A; MEL; RAB8
Study 1727807 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 16101180 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7717184 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2149509 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2149509 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 16901714 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15113716 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11795364 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9555667 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20200547 — Surrogate Endpoint (SUR): Blood pressure
Study 8335833 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2967855 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 31517396 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Chitinase-3-like protein 1
Genes: CHI3L1
Study 14734879 — Surrogate Endpoint (SUR): Serum creatinine
Study 14734879 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28259853 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 31912198 — Safety Biomarker (SAF): Human leucocyte antigen
Study 7915501 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31504596 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17426000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17426000 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7879930 — Surrogate Endpoint (SUR): Blood pressure
Study 7613114 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7613114 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 2152972 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11805557 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7510078 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 2133624 — Predictive Biomarker (PRD): RETREG2 mRNA
Genes: RETREG2; C2orf17; FAM134A; MAG2
Study 30311367 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 28588304 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 21804623 — Surrogate Endpoint (SUR): Blood pressure
Study 21804623 — Surrogate Endpoint (SUR): Serum potassium
Study 23731498 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 23731498 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16901644 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 16901644 — Safety Biomarker (SAF): DRD2
Study 14604600 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 14604600 — Surrogate Endpoint (SUR): Blood pressure
Study 31228006 — Surrogate Endpoint (SUR): Blood pressure
Study 24096771 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 11153048 — Surrogate Endpoint (SUR): Blood pressure
Study 29371133 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 27347698 — Surrogate Endpoint (SUR): Blood pressure
Study 27347698 — Surrogate Endpoint (SUR): Serum potassium
Study 29906425 — Surrogate Endpoint (SUR): Blood pressure
Study 22197980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22197980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12002714 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 25460556 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24060891 — Surrogate Endpoint (SUR): Blood pressure
Study 10506613 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15790691 — Surrogate Endpoint (SUR): Blood pressure
Study 31756496 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 25388434 — Surrogate Endpoint (SUR): Blood pressure
Study 25388434 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22762896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21522004 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15459836 — Surrogate Endpoint (SUR): Bone mineral density
Study 23624785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23624785 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 23624785 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16813176 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 12932752 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 11038198 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11038198 — Predictive Biomarker (PRD): Hormone receptor
Study 8777834 — Surrogate Endpoint (SUR): Blood pressure
Study 27893473 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27893473 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22770377 — Safety Biomarker (SAF): Reactive oxygen species
Study 20581169 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 20581169 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15129736 — Surrogate Endpoint (SUR): Blood pressure
Study 22935440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 22935440 — Surrogate Endpoint (SUR): Blood pressure
Study 25116461 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 2350628 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 30259172 — Surrogate Endpoint (SUR): Serum creatinine
Study 17261465 — Surrogate Endpoint (SUR): Blood pressure
Study 15037412 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24085261 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21392603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10556107 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 8818828 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1823530 — Surrogate Endpoint (SUR): Blood pressure
Study 1823530 — Surrogate Endpoint (SUR): Serum creatinine
Study 6827129 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 6827129 — Safety Biomarker (SAF): Succinate-semialdehyde dehydrogenase
Genes: ALDH5A1; SSADH
Study 27035157 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 19540162 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31079533 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 28497384 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23331510 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6398984 — Surrogate Endpoint (SUR): Blood pressure
Study 10724301 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30712923 — Surrogate Endpoint (SUR): Blood pressure
Study 22182296 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 7506007 — Surrogate Endpoint (SUR): Blood pressure
Study 7506007 — Surrogate Endpoint (SUR): Serum potassium
Study 2554357 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25501057 — Surrogate Endpoint (SUR): Blood pressure
Study 15153576 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 7957495 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7957495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28857425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28857425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28857425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23617712 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 28858247 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15817818 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 2898901 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1420630 — Surrogate Endpoint (SUR): Blood pressure
Study 27509600 — Surrogate Endpoint (SUR): Blood pressure
Study 2043298 — Surrogate Endpoint (SUR): Blood pressure
Study 2043298 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6461999 — Surrogate Endpoint (SUR): Blood pressure
Study 31348595 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16718798 — Surrogate Endpoint (SUR): Blood pressure
Study 30916364 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30216191 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 2095345 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 30452776 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 23735727 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 16671435 — Surrogate Endpoint (SUR): Blood pressure
Study 31623638 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27866873 — Surrogate Endpoint (SUR): Serum creatinine
Study 11169032 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9504950 — Surrogate Endpoint (SUR): Bone mineral density
Study 20525274 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 12441212 — Surrogate Endpoint (SUR): Blood pressure
Study 6104874 — Surrogate Endpoint (SUR): Blood pressure
Study 17602978 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24570078 — Surrogate Endpoint (SUR): Serum creatinine
Study 16186280 — Surrogate Endpoint (SUR): Blood pressure
Study 11018196 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1320241 — Surrogate Endpoint (SUR): Blood pressure
Study 30970186 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 28339668 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 21892586 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19647104 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 9159839 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17403837 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8584771 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28385543 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 28385543 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 25281416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23448846 — Surrogate Endpoint (SUR): Blood pressure
Study 12536732 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 25050884 — Surrogate Endpoint (SUR): Blood pressure
Study 23333252 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 12567389 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12567389 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10680790 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 29784057 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 24328800 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 23302603 — Surrogate Endpoint (SUR): Blood pressure
Study 21272091 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 19541816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8361890 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26198283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25448515 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27401037 — Surrogate Endpoint (SUR): Serum calcium
Study 27401037 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 16821204 — Surrogate Endpoint (SUR): Bone mineral density
Study 16821204 — Surrogate Endpoint (SUR): Serum calcium
Study 11918754 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2789932 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 29432772 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29432772 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 29432772 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29432772 — Surrogate Endpoint (SUR): Blood pressure
Study 26555123 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23216520 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 20137557 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 20137557 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20137557 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20137557 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17367658 — Surrogate Endpoint (SUR): Blood pressure
Study 15253102 — Surrogate Endpoint (SUR): Blood pressure
Study 15253102 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11454260 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31980145 — Surrogate Endpoint (SUR): Pathological complete response
Study 25400085 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 24576194 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21253451 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10150320 — Surrogate Endpoint (SUR): Blood pressure
Study 28231660 — Monitoring Biomarker (MOI): HBV DNA
Study 23273588 — Surrogate Endpoint (SUR): Serum sodium
Study 30509268 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30509268 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18514620 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12074417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12074417 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12074417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10385780 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10385780 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28298024 — Safety Biomarker (SAF): Interleukin 1
Study 28298024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24517632 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20170522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11911720 — Surrogate Endpoint (SUR): Bone mineral density
Study 29023938 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21573987 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 15235901 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7649670 — Surrogate Endpoint (SUR): Blood pressure
Study 17465506 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17465506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17465506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25300285 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25300285 — Surrogate Endpoint (SUR): Blood pressure
Study 25300285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25300285 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 25300285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25300285 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26859091 — Surrogate Endpoint (SUR): Bacterial count
Study 26859091 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22948092 — Surrogate Endpoint (SUR): Blood pressure
Study 22948092 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22948092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22948092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11232964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30396037 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26807502 — Surrogate Endpoint (SUR): Serum creatinine
Study 17687719 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31003676 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31003676 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25740387 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23497452 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22020892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22020892 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1