TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19746242 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 11488132 — Surrogate Endpoint (SUR): Blood pressure
Study 2897785 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 2897785 — Surrogate Endpoint (SUR): Plasma ammonia
Study 16616744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16616744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16616744 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 14669258 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9085939 — Safety Biomarker (SAF): Interleukin 1
Study 9085939 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9085939 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1493941 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3159197 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10407502 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29024278 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 8797613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1632683 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30641007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30641007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30641007 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30641007 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22124360 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 25858261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25858261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21142946 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21142946 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21142946 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19172254 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19172254 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11334901 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20800340 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12792559 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27898732 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 27898732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12657163 — Surrogate Endpoint (SUR): Blood pressure
Study 29975565 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29975565 — Surrogate Endpoint (SUR): Blood pressure
Study 26559450 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26559450 — Surrogate Endpoint (SUR): Blood pressure
Study 9793813 — Surrogate Endpoint (SUR): Blood pressure
Study 2628637 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23535165 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 23535165 — Predictive Biomarker (PRD): SCARA3 mRNA
Genes: SCARA3; CSR
Study 21818634 — Predictive Biomarker (PRD): TNFRSF1A
Genes: TNF-R; TNFAR; TNFR60; TNF-R-I; CD120a; TNF-R55
Study 6364879 — Surrogate Endpoint (SUR): Blood pressure
Study 12092742 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12092742 — Surrogate Endpoint (SUR): Blood pressure
Study 12092742 — Surrogate Endpoint (SUR): Serum potassium
Study 26021226 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 26021226 — Safety Biomarker (SAF): Interleukin 1
Study 26021226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26021226 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9544865 — Surrogate Endpoint (SUR): Blood pressure
Study 31518640 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 31518640 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28329334 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18043700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 3404500 — Surrogate Endpoint (SUR): Blood pressure
Study 21929307 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 8292702 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8292702 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24430787 — Surrogate Endpoint (SUR): Blood pressure
Study 10852458 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 8449049 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24878942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24878942 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24878942 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20190383 — Surrogate Endpoint (SUR): Bone mineral density
Study 21868730 — Surrogate Endpoint (SUR): Blood pressure
Study 19154802 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 19154802 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 28110412 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 8070497 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8070497 — Surrogate Endpoint (SUR): Blood pressure
Study 15578470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15578470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11453957 — Surrogate Endpoint (SUR): Bone mineral density
Study 9209724 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28268074 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 26536057 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 17012141 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7015795 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20717875 — Surrogate Endpoint (SUR): Blood pressure
Study 20717875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12851876 — Monitoring Biomarker (MOI): HBV DNA
Study 8740244 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 28209040 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19573637 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 23388527 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 17012419 — Surrogate Endpoint (SUR): Bone mineral density
Study 9235470 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 1604411 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 22867101 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7553405 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7553405 — Surrogate Endpoint (SUR): Blood pressure
Study 27241125 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 27241125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27241125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27241125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24935272 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22343498 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 16224157 — Monitoring Biomarker (MOI): HBV DNA
Study 21088595 — Surrogate Endpoint (SUR): Blood pressure
Study 15470213 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28190788 — Surrogate Endpoint (SUR): Blood pressure
Study 16504957 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15575830 — Surrogate Endpoint (SUR): Forced vital capacity
Study 6439759 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 6439759 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10657535 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 10657535 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8527287 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 8527287 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 30835822 — Safety Biomarker (SAF): BDNF
Study 22232815 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 1540729 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1540729 — Surrogate Endpoint (SUR): Blood pressure
Study 30429415 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21832111 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 15289792 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31786810 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 28715540 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 28715540 — Predictive Biomarker (PRD): MACF1 mRNA
Genes: MACF1; KIAA0754
Study 28715540 — Predictive Biomarker (PRD): SPRY2 mRNA
Genes: SPRY2
Study 28715540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15898218 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28543873 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 28543873 — Surrogate Endpoint (SUR): Bone mineral density
Study 22832429 — Predictive Biomarker (PRD): IRF7 mRNA
Genes: IRF7
Study 9072600 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27207965 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22944873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15377472 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9590570 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9590570 — Surrogate Endpoint (SUR): Blood pressure
Study 24656288 — Surrogate Endpoint (SUR): Serum uric acid
Study 22410401 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 15723993 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11137103 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11137103 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8059505 — Surrogate Endpoint (SUR): Sperm parameters
Study 27468867 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27468867 — Monitoring Biomarker (MOI): Cell-free DNA
Study 26233572 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19110788 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 8471818 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3402353 — Surrogate Endpoint (SUR): Blood pressure
Study 28097295 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17299064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17299064 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17299064 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17299064 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7750429 — Surrogate Endpoint (SUR): Blood pressure
Study 31883223 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30509771 — Predictive Biomarker (PRD): Hormone receptor
Study 30509771 — Surrogate Endpoint (SUR): Bone mineral density
Study 30292279 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 26808474 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24471979 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 16297748 — Surrogate Endpoint (SUR): Blood pressure
Study 9705040 — Surrogate Endpoint (SUR): Blood pressure
Study 24095239 — Safety Biomarker (SAF): Hyaluronic acid
Study 21970555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21970555 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 21970555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21970555 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21970555 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10868823 — Surrogate Endpoint (SUR): Blood pressure
Study 8844349 — Safety Biomarker (SAF): Hyaluronic acid
Study 1321186 — Surrogate Endpoint (SUR): Blood pressure
Study 1321186 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 23770470 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 16553675 — Surrogate Endpoint (SUR): Blood pressure
Study 2853764 — Surrogate Endpoint (SUR): Blood pressure
Study 12769163 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12769163 — Surrogate Endpoint (SUR): Blood pressure
Study 16099715 — Surrogate Endpoint (SUR): Blood pressure
Study 20067609 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 21945258 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 11896424 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11896424 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3178370 — Surrogate Endpoint (SUR): Blood pressure
Study 16035956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12514674 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17963865 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 15987488 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 15987488 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 2545454 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2545454 — Surrogate Endpoint (SUR): Blood pressure
Study 8345497 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 3453186 — Surrogate Endpoint (SUR): Blood pressure
Study 27091810 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22108774 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22108774 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 15516364 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 14533141 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31051056 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 11113721 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24838809 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 24838809 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study 10430348 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 22643131 — Predictive Biomarker (PRD): SLC12A2 mRNA
Genes: SLC12A2; NKCC1
Study 9503102 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25948437 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18946064 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 8986493 — Surrogate Endpoint (SUR): Blood pressure
Study 2172535 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30957213 — Surrogate Endpoint (SUR): Serum potassium
Study 11588409 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11588409 — Surrogate Endpoint (SUR): Blood pressure
Study 11588409 — Surrogate Endpoint (SUR): Serum creatinine
Study 9632325 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 2574084 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 31533093 — Surrogate Endpoint (SUR): Serum creatinine
Study 26468478 — Surrogate Endpoint (SUR): Blood pressure
Study 8269183 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8269183 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2994988 — Surrogate Endpoint (SUR): Blood pressure
Study 25925484 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23049590 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 14624393 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14624393 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8260371 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25436661 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 20732526 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 20732526 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20732526 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 16192766 — Surrogate Endpoint (SUR): Blood pressure
Study 12814476 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10385641 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 10385641 — Predictive Biomarker (PRD): RNASE2 mRNA
Genes: RNASE2; EDN; RNS2
Study 11818522 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 2117147 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 26204331 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26204331 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23709289 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11253161 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11253161 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9200286 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 30993861 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9630109 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28407408 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study 12894480 — Monitoring Biomarker (MOI): HBV DNA
Study 8508009 — Surrogate Endpoint (SUR): Blood pressure
Study 24728578 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24728578 — Surrogate Endpoint (SUR): Pathological complete response
Study 20185595 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 20185595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28760693 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 27237598 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21691934 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17356308 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 8125421 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8125421 — Surrogate Endpoint (SUR): Blood pressure
Study 23848184 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9814449 — Surrogate Endpoint (SUR): Bone mineral density
Study 9814449 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2574045 — Surrogate Endpoint (SUR): Blood pressure
Study 18380771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18380771 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 14620923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14620923 — Surrogate Endpoint (SUR): Blood pressure
Study 8630662 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8630662 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16317760 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 9140705 — Surrogate Endpoint (SUR): Blood pressure
Study 23951825 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 21914162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10354218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10354218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8877260 — Surrogate Endpoint (SUR): Blood pressure
Study 8877260 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7113575 — Surrogate Endpoint (SUR): Blood pressure
Study 8834645 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 24440167 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 24440167 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16389742 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 9052903 — Surrogate Endpoint (SUR): Blood pressure
Study 8306902 — Surrogate Endpoint (SUR): Blood pressure
Study 21593349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16965910 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16965910 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 16965910 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 10899363 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 29329233 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP