TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26416897 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26416897 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 26416897 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 26416897 — Predictive Biomarker (PRD): NFKB1 mRNA
Genes: NFKB1
Study 26416897 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 26416897 — Pharmacodynamic Biomarker (PDY): Interferon regulatory factor 3
Genes: IRF3
Study 26416897 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26416897 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26416897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 26417268 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 26417268 — Surrogate Endpoint (SUR): Blood pressure
Study 26419198 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 26420684 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26420854 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study 26420854 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 26423721 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 26423749 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 26423811 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26423989 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 26423989 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26424605 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 26425877 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26425877 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 26427420 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 26427534 — Surrogate Endpoint (SUR): Blood pressure
Study 26427727 — Predictive Biomarker (PRD): Chromosome 5q
Study 26428846 — Predictive Biomarker (PRD): PPP6R3 mRNA
Genes: PPP6R3; C11orf23; KIAA1558; PP6R3; SAPL; SAPS3
Study 26428987 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26429296 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26430171 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26430465 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 26430465 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 26430465 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 26430892 — Surrogate Endpoint (SUR): Serum calcium
Study 26432046 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 26432046 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 26432046 — Surrogate Endpoint (SUR): Serum creatinine
Study 26435425 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26436448 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 26437664 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26438201 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26439440 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 26440706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 26440706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26441570 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26444282 — Safety Biomarker (SAF): Interleukin 1
Study 26445642 — Surrogate Endpoint (SUR): Blood pressure
Study 26445642 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26445924 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26446126 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 26446491 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26446491 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26446943 — Monitoring Biomarker (MOI): Cell-free DNA
Study 26447149 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26447158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26448724 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26448868 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 26449490 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26449993 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26451310 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 26452027 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26452027 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 26452027 — Monitoring Biomarker (MOI): Cell-free DNA
Study 26452397 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26452561 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 26454362 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 26454612 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26455892 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 26458804 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 26459220 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26459812 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26459812 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 26459812 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26459932 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 26460303 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 26460303 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26460303 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26460303 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 26460303 — Predictive Biomarker (PRD): Microsatellite instability
Study 26464715 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study 26464803 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26465780 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26466682 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26467555 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 26467555 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 26468228 — Predictive Biomarker (PRD): SOX2 mRNA
Genes: SOX2
Study 26468228 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26472401 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26472401 — Monitoring Biomarker (MOI): Procalcitonin
Study 26472629 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 26472751 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 26473643 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26473643 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 26473643 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26473643 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 26474455 — Predictive Biomarker (PRD): HDAC9 mRNA
Genes: HDAC9; HDAC7; HDAC7B; HDRP; KIAA0744; MITR
Study 26474455 — Predictive Biomarker (PRD): AVEN mRNA
Genes: AVEN
Study 26474455 — Predictive Biomarker (PRD): SEMA3C mRNA
Genes: SEMA3C; SEMAE
Study 26474455 — Predictive Biomarker (PRD): IKBKB mRNA
Genes: IKBKB; IKKB
Study 26474455 — Predictive Biomarker (PRD): GSTA3 mRNA
Genes: GSTA3
Study 26474455 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 26474455 — Predictive Biomarker (PRD): SLC15A1 mRNA
Genes: SLC15A1; PEPT1
Study 26474455 — Predictive Biomarker (PRD): PSMB10 mRNA
Genes: PSMB10; LMP10; MECL1
Study 26474455 — Predictive Biomarker (PRD): TNFRSF10D mRNA
Genes: TNFRSF10D; DCR2; TRAILR4; TRUNDD; UNQ251/PRO288
Study 26474455 — Predictive Biomarker (PRD): PSMB2 mRNA
Genes: PSMB2
Study 26475140 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 26476290 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 26476503 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 26477337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26477337 — Surrogate Endpoint (SUR): Serum potassium
Study 26477497 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 26477820 — Predictive Biomarker (PRD): NFKBIA mRNA
Genes: NFKBIA; IKBA; MAD3; NFKBI
Study 26481915 — Surrogate Endpoint (SUR): Blood pressure
Study 26482301 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 26482895 — Surrogate Endpoint (SUR): Blood pressure
Study 26482997 — Surrogate Endpoint (SUR): Serum creatinine
Study 26483108 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26483516 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26485680 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 26488758 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 26489933 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 26490103 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26490103 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 26492847 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 26492847 — Predictive Biomarker (PRD): LGSN mRNA
Genes: LGSN; GLULD1; LGS
Study 26492921 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 26492921 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26494259 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26494259 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 26495926 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26495926 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26499223 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 26500687 — Predictive Biomarker (PRD): FABP4 mRNA
Genes: FABP4
Study 26502894 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study 26507836 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26507877 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 26508901 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 26509071 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26509074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26510020 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 26510020 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study 26510020 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 26510696 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 26511652 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 26511652 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26511835 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 26516010 — Predictive Biomarker (PRD): APOC3 mRNA
Genes: APOC3
Study 26520062 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26523525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26525557 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26526622 — Surrogate Endpoint (SUR): Serum potassium
Study 26527780 — Predictive Biomarker (PRD): NRM mRNA
Genes: NRM; NRM29; UNQ555/PRO1112
Study 26528500 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 26528879 — Monitoring Biomarker (MOI): Procalcitonin
Study 26528879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26529238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26529255 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 26529255 — Predictive Biomarker (PRD): SIRT3 mRNA
Genes: SIRT3; SIR2L3
Study 26530268 — Surrogate Endpoint (SUR): Blood pressure
Study 26530268 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26531748 — Predictive Biomarker (PRD): MAPK8IP2 mRNA
Genes: MAPK8IP2; IB2; JIP2; PRKM8IPL
Study 26535134 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 26535134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26535134 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 26536893 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study 26537529 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 26537529 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 26537529 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 26537851 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 26538309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26538309 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26538477 — Surrogate Endpoint (SUR): Blood pressure
Study 26539981 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26540234 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26540612 — Surrogate Endpoint (SUR): Blood pressure
Study 26542378 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 26543510 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26543765 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26543765 — Predictive Biomarker (PRD): TCAP mRNA
Genes: TCAP
Study 26543765 — Predictive Biomarker (PRD): GSDMB mRNA
Genes: GSDMB; GSDML; PP4052; PRO2521
Study 26543906 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 26544725 — Surrogate Endpoint (SUR): Blood pressure
Study 26545911 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26545911 — Safety Biomarker (SAF): MTHFR
Study 26546259 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 26547188 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26552419 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 26552419 — Predictive Biomarker (PRD): Microsatellite instability
Study 26553695 — Predictive Biomarker (PRD): RUNX2 mRNA
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 26553695 — Predictive Biomarker (PRD): CACNA1C mRNA
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 26553837 — Predictive Biomarker (PRD): ZDHHC2 mRNA
Genes: ZDHHC2; REAM; REC; ZNF372
Study 26554876 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 26555635 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 26555635 — Surrogate Endpoint (SUR): Bone mineral density
Study 26555635 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26558819 — Surrogate Endpoint (SUR): Blood pressure
Study 26562836 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26562836 — Surrogate Endpoint (SUR): Serum creatinine
Study 26565381 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 26565381 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study 26565813 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 26565813 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 26565813 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 26565813 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 26566914 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 26567113 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 26567120 — Surrogate Endpoint (SUR): Blood pressure
Study 26567860 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26567860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26567860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26568833 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26569533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26571268 — Predictive Biomarker (PRD): KCNN1 mRNA
Genes: KCNN1; SK
Study 26571311 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26573078 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 26574583 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 26574583 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 26575422 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26576546 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 26576744 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26576744 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26577132 — Surrogate Endpoint (SUR): Blood pressure
Study 26577754 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 26578201 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 26578201 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 26578401 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26578722 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26578731 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26579227 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26579227 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26579227 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 26579227 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 26579227 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 26579723 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 26579723 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 26581547 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26583585 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 26583585 — Predictive Biomarker (PRD): COL3A1 mRNA
Genes: COL3A1
Study 26583585 — Predictive Biomarker (PRD): COL6A1 mRNA
Genes: COL6A1
Study 26583585 — Predictive Biomarker (PRD): COL6A2 mRNA
Genes: COL6A2
Study 26583585 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study 26583585 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 26583585 — Predictive Biomarker (PRD): LOXL4 mRNA
Genes: LOXL4; LOXC
Study 26584787 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26584787 — Surrogate Endpoint (SUR): Serum creatinine
Study 26585432 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26588924 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 26589752 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 26589752 — Surrogate Endpoint (SUR): Hematologic response
Study 26590174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26590194 — Predictive Biomarker (PRD): BMP7 mRNA
Genes: BMP7; OP1
Study 26590194 — Predictive Biomarker (PRD): PROX1 mRNA
Genes: PROX1
Study 26596948 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 26597180 — Predictive Biomarker (PRD): NE
Study 26597824 — Surrogate Endpoint (SUR): Blood pressure
Study 26598545 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26599244 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 26599344 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26602013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 26602164 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 26602164 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 26602164 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 26602164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 26605506 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26605506 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 26606398 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26606398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26608460 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26612873 — Surrogate Endpoint (SUR): Serum creatinine
Study 26614268 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 26614268 — Surrogate Endpoint (SUR): Serum creatinine
Study 26614807 — Predictive Biomarker (PRD): LRRN3 mRNA
Genes: LRRN3; Nbla10363; UNQ194/PRO220
Study 26614807 — Predictive Biomarker (PRD): SASH1 mRNA
Genes: SASH1; KIAA0790; PEPE1
Study 26614807 — Predictive Biomarker (PRD): PALLD mRNA
Genes: PALLD; KIAA0992; CGI-151
Study 26614807 — Predictive Biomarker (PRD): RGL1 mRNA
Genes: RGL1; KIAA0959; RGL
Study 26614807 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 26614807 — Predictive Biomarker (PRD): CDKN1C mRNA
Genes: CDKN1C; KIP2
Study 26614807 — Predictive Biomarker (PRD): JCHAIN mRNA
Genes: JCHAIN; IGCJ; IGJ
Study 26614807 — Predictive Biomarker (PRD): RRM2 mRNA
Genes: RRM2; RR2
Study 26614807 — Predictive Biomarker (PRD): ID3 mRNA
Genes: ID3; 1R21; BHLHB25; HEIR1