TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30710858 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 10368452 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 10368452 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26296069 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24437213 — Surrogate Endpoint (SUR): Blood pressure
Study 27343021 — Surrogate Endpoint (SUR): Blood pressure
Study 16651463 — Surrogate Endpoint (SUR): Blood pressure
Study 1539469 — Surrogate Endpoint (SUR): Blood pressure
Study 11192307 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 25363733 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 25363733 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 16312178 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2361594 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 29809075 — Surrogate Endpoint (SUR): Blood pressure
Study 16856976 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 16856976 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 8877664 — Surrogate Endpoint (SUR): Probing pocket depth
Study 6137293 — Surrogate Endpoint (SUR): Blood pressure
Study 15467292 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 28668276 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28668276 — Surrogate Endpoint (SUR): Blood pressure
Study 19089438 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19089438 — Surrogate Endpoint (SUR): Blood pressure
Study 2906953 — Surrogate Endpoint (SUR): Blood pressure
Study 29893790 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29893790 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20019672 — Surrogate Endpoint (SUR): Blood pressure
Study 18614956 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26657066 — Safety Biomarker (SAF): miR-22
Genes: MIR22
Study 26657066 — Predictive Biomarker (PRD): let-7b
Genes: MIRLET7B
Study 26657066 — Safety Biomarker (SAF): miR-200a
Genes: MIR200A
Study 12149660 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12149660 — Surrogate Endpoint (SUR): Blood pressure
Study 30287210 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22284340 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22284340 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19080711 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 16882108 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16882108 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31537219 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30161205 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26794168 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 25811824 — Surrogate Endpoint (SUR): Blood pressure
Study 25811824 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25811824 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22339238 — Surrogate Endpoint (SUR): Blood pressure
Study 19298023 — Safety Biomarker (SAF): PPOX
Genes: HCRT; OX
Study 15778240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9028511 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1900480 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 31634646 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24356952 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 24356952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18025884 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18025884 — Surrogate Endpoint (SUR): Bone mineral density
Study 10426837 — Surrogate Endpoint (SUR): Blood pressure
Study 11839994 — Surrogate Endpoint (SUR): Blood pressure
Study 31222379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15604915 — Predictive Biomarker (PRD): ADM2 mRNA
Genes: ADM2; AM2
Study 11289051 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11289051 — Surrogate Endpoint (SUR): Blood pressure
Study 9647874 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7847107 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 7847107 — Surrogate Endpoint (SUR): Serum calcium
Study 1971778 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31358390 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 31358390 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 2903105 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2903105 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study 24622413 — Surrogate Endpoint (SUR): Serum calcium
Study 17927495 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27484126 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 10658943 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10658943 — Surrogate Endpoint (SUR): Blood pressure
Study 8574257 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8574257 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 518286 — Surrogate Endpoint (SUR): Plasma testosterone level
Study 3110562 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29940888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29940888 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study 25245386 — Surrogate Endpoint (SUR): Blood pressure
Study 22673596 — Predictive Biomarker (PRD): GYPC mRNA
Genes: GYPC; GLPC; GPC
Study 18822979 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 18822979 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 18822979 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23747768 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20354688 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 18191056 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3905326 — Surrogate Endpoint (SUR): Serum potassium
Study 26748844 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10720024 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28202441 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 23648698 — Surrogate Endpoint (SUR): Blood pressure
Study 6361300 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6361300 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24904022 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 22442825 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19736246 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 19736246 — Surrogate Endpoint (SUR): Serum calcium
Study 19736246 — Surrogate Endpoint (SUR): Serum uric acid
Study 18932258 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 14507272 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31999530 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26872548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26872548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21030711 — Surrogate Endpoint (SUR): Blood pressure
Study 7609571 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29083331 — Surrogate Endpoint (SUR): Serum potassium
Study 29083331 — Surrogate Endpoint (SUR): Blood pressure
Study 21593114 — Surrogate Endpoint (SUR): Bone mineral density
Study 2875812 — Surrogate Endpoint (SUR): Blood pressure
Study 2875812 — Safety Biomarker (SAF): Succinate-semialdehyde dehydrogenase
Genes: ALDH5A1; SSADH
Study 29635061 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 24585406 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23109900 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 23109900 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 23109900 — Predictive Biomarker (PRD): LIPG mRNA
Genes: LIPG; UNQ387/PRO719
Study 23109900 — Predictive Biomarker (PRD): MYLIP mRNA
Genes: MYLIP; BZF1; IDOL; BM-023; PP5242
Study 23109900 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 23109900 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor delta
Genes: PPARD
Study 23109900 — Predictive Biomarker (PRD): SCARB1 mRNA
Genes: SCARB1; CD36L1; CLA1
Study 16061592 — Surrogate Endpoint (SUR): Blood pressure
Study 2148735 — Surrogate Endpoint (SUR): Blood pressure
Study 29158123 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29158123 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17493710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17493710 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16179039 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1713985 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1713985 — Surrogate Endpoint (SUR): Blood pressure
Study 15886989 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study 24497205 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8474402 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28698009 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 16633141 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 16633141 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7851061 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7851061 — Surrogate Endpoint (SUR): Blood pressure
Study 23123925 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15247013 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 14667998 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 14667998 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9678101 — Surrogate Endpoint (SUR): Bone mineral density
Study 18249330 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 11220295 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26253622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 12911777 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 2868771 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 17917707 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16873787 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10739792 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10739792 — Surrogate Endpoint (SUR): Serum creatinine
Study 1398281 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 13679933 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 13679933 — Surrogate Endpoint (SUR): Blood pressure
Study 3935203 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 21909729 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 21909729 — Surrogate Endpoint (SUR): Bone mineral density
Study 9228466 — Surrogate Endpoint (SUR): Bone mineral density
Study 28902040 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28902040 — Surrogate Endpoint (SUR): Serum creatinine
Study 28902040 — Surrogate Endpoint (SUR): Serum sodium
Study 21489086 — Surrogate Endpoint (SUR): Serum creatinine
Study 19036752 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11291999 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 3003259 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26458326 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study 26458326 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8745672 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25088940 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25088940 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17501848 — Predictive Biomarker (PRD): FAIM mRNA
Genes: FAIM; FAIM1
Study 11684631 — Surrogate Endpoint (SUR): Blood pressure
Study 30661948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16289322 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16289322 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 16289322 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16289322 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 14674205 — Surrogate Endpoint (SUR): Serum testosterone
Study 20049491 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 31786154 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 30946378 — Surrogate Endpoint (SUR): Blood pressure
Study 30946378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30946378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19454518 — Safety Biomarker (SAF): Hyaluronic acid
Study 12399074 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2699823 — Surrogate Endpoint (SUR): Blood pressure
Study 23663341 — Surrogate Endpoint (SUR): Blood pressure
Study 17109338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17109338 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3280855 — Surrogate Endpoint (SUR): Serum calcium
Study 3280855 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17995967 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 1497127 — Surrogate Endpoint (SUR): Blood pressure
Study 29130647 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 16266860 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17008634 — Surrogate Endpoint (SUR): Blood pressure
Study 12580231 — Surrogate Endpoint (SUR): Blood pressure
Study 6337801 — Surrogate Endpoint (SUR): Blood pressure