TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1702449 — Predictive Biomarker (PRD): GRHL3 mRNA
Genes: GRHL3; SOM; TFCP2L4
Study 31350847 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 31350847 — Predictive Biomarker (PRD): CSF3R mRNA
Genes: CSF3R; GCSFR
Study 31350847 — Predictive Biomarker (PRD): E2F2 mRNA
Genes: E2F2
Study 31350847 — Predictive Biomarker (PRD): JUP mRNA
Genes: JUP; CTNNG; DP3
Study 31350847 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study 31350847 — Predictive Biomarker (PRD): TCF7 mRNA
Genes: TCF7; TCF1
Study 24169081 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 1704983 — Surrogate Endpoint (SUR): Blood pressure
Study 168121 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 687499 — Surrogate Endpoint (SUR): Blood pressure
Study 29963733 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 25830782 — Surrogate Endpoint (SUR): Blood pressure
Study 23998234 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 21430660 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21430660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21430660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18180893 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18180893 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11207464 — Surrogate Endpoint (SUR): Blood pressure
Study 9435413 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31468673 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31468673 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 31468673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 31468673 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31468673 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20621377 — Surrogate Endpoint (SUR): Blood pressure
Study 18416220 — Monitoring Biomarker (MOI): Procalcitonin
Study 9639442 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18349403 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 10762214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8272478 — Surrogate Endpoint (SUR): Blood pressure
Study 3802705 — Surrogate Endpoint (SUR): Blood pressure
Study 20413522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7757354 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 30681939 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27951450 — Predictive Biomarker (PRD): Hormone receptor
Study 26154930 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26154930 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26154930 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26154930 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 26154930 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 22166738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15224273 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 11423921 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11423921 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9243749 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 9243749 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 7961239 — Surrogate Endpoint (SUR): Blood pressure
Study 3591419 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3591419 — Surrogate Endpoint (SUR): Blood pressure
Study 20444849 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19040592 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19040592 — Surrogate Endpoint (SUR): Blood pressure
Study 2591463 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2591463 — Surrogate Endpoint (SUR): Blood pressure
Study 21903021 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12754885 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8815481 — Surrogate Endpoint (SUR): Serum creatinine
Study 21523325 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18204476 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16055956 — Surrogate Endpoint (SUR): Bone mineral density
Study 10469339 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10469339 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 10469339 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10469339 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 2186579 — Surrogate Endpoint (SUR): Serum sodium
Study 37747 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 37747 — Surrogate Endpoint (SUR): Serum calcium
Study 21551506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17164314 — Surrogate Endpoint (SUR): Serum calcium
Study 30398646 — Predictive Biomarker (PRD): GLO1 mRNA
Genes: GLO1
Study 20447925 — Predictive Biomarker (PRD): MCM6 mRNA
Genes: MCM6
Study 7124311 — Surrogate Endpoint (SUR): Blood pressure
Study 28743816 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28743816 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26729441 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 14750091 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14750091 — Surrogate Endpoint (SUR): Blood pressure
Study 16585662 — Surrogate Endpoint (SUR): Blood pressure
Study 25891453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25891453 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25891453 — Surrogate Endpoint (SUR): Serum creatinine
Study 20938444 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8922355 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 30887760 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 14712431 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 7986302 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7986302 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28371685 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28371685 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23635604 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 23635604 — Safety Biomarker (SAF): Reactive oxygen species
Study 10768435 — Surrogate Endpoint (SUR): Serum potassium
Study 11548874 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 11548874 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11548874 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11548874 — Surrogate Endpoint (SUR): Blood pressure
Study 30929250 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30929250 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21797975 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 16772388 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11523071 — Surrogate Endpoint (SUR): Blood pressure
Study 8380631 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 28128223 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 26200619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26200619 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1533941 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 2908814 — Surrogate Endpoint (SUR): Blood pressure
Study 27271183 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11383326 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11383326 — Surrogate Endpoint (SUR): Blood pressure
Study 8067227 — Surrogate Endpoint (SUR): Blood pressure
Study 23298135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23298135 — Surrogate Endpoint (SUR): Blood pressure
Study 27780504 — Surrogate Endpoint (SUR): Bone mineral density
Study 20826964 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 14619332 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 28139626 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 12798823 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6178592 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 6178592 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 19922896 — Surrogate Endpoint (SUR): Blood pressure
Study 10423601 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10423601 — Surrogate Endpoint (SUR): Blood pressure
Study 7943382 — Surrogate Endpoint (SUR): Blood pressure
Study 28215316 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28215316 — Surrogate Endpoint (SUR): Blood pressure
Study 23811808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10872898 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26932345 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26932345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26932345 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18272891 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 16204792 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8390084 — Surrogate Endpoint (SUR): Bone mineral density
Study 31674093 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 10619534 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 616209 — Surrogate Endpoint (SUR): Blood pressure
Study 16303780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16303780 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15504192 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2467137 — Surrogate Endpoint (SUR): Blood pressure
Study 28148474 — Surrogate Endpoint (SUR): Blood pressure
Study 23680036 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23680036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23680036 — Surrogate Endpoint (SUR): Blood pressure
Study 16271817 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 6337405 — Surrogate Endpoint (SUR): Blood pressure
Study 30286797 — Surrogate Endpoint (SUR): Blood pressure
Study 24648302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24648302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24648302 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 19660897 — Surrogate Endpoint (SUR): Blood pressure
Study 15538130 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15538130 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 25040896 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 25040896 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26585287 — Predictive Biomarker (PRD): PNOC mRNA
Genes: PNOC; OFQ
Study 26585287 — Predictive Biomarker (PRD): NOL3 mRNA
Genes: NOL3; ARC; NOP
Study 23767831 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23767831 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23767831 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 24708917 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 24708917 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20555331 — Surrogate Endpoint (SUR): Blood pressure
Study 20555331 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8910175 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 8910175 — Surrogate Endpoint (SUR): Blood pressure
Study 8910175 — Surrogate Endpoint (SUR): Serum creatinine
Study 6359947 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29666026 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29666026 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29666026 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 29666026 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28972045 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 28972045 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 28972045 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 28972045 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 17690191 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31429629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20942668 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 18219181 — Surrogate Endpoint (SUR): Bone mineral density
Study 16845627 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 16845627 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7989949 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7989949 — Surrogate Endpoint (SUR): Serum creatinine
Study 24799100 — Surrogate Endpoint (SUR): Blood pressure
Study 16368883 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 11739159 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 26813432 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26813432 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 26813432 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 23797426 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 16328487 — Surrogate Endpoint (SUR): Blood pressure
Study 9131955 — Surrogate Endpoint (SUR): Blood pressure
Study 8383769 — Surrogate Endpoint (SUR): Blood pressure
Study 8383769 — Surrogate Endpoint (SUR): Serum sodium
Study 28470118 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): miR-124
Study 28470118 — Safety Biomarker (SAF): miR-375-3p
Genes: MIR375
Study 28470118 — Safety Biomarker (SAF): miR-375
Genes: MIR375
Study 28470118 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-150
Genes: MIR150
Study 28470118 — Predictive Biomarker (PRD): miR-31
Genes: MIR31
Study 11531679 — Surrogate Endpoint (SUR): Blood pressure
Study 8315260 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8315260 — Monitoring Biomarker (MOI): HBV DNA
Study 2894218 — Surrogate Endpoint (SUR): Blood pressure
Study 23746559 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 30842392 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27739325 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 27739325 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 23490598 — Surrogate Endpoint (SUR): Blood pressure
Study 23490598 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11967790 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3914572 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 30940692 — Pharmacodynamic Biomarker (PDY): Phosphatidylinositol-trisphosphate
Study 30144891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30144891 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 7857734 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7857734 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7857734 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24744152 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22113951 — Surrogate Endpoint (SUR): Bone mineral density
Study 19134277 — Surrogate Endpoint (SUR): Serum creatinine
Study 1720217 — Surrogate Endpoint (SUR): Blood pressure
Study 1720217 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29754649 — Surrogate Endpoint (SUR): Blood pressure
Study 29754649 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17911647 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12364969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2142577 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2142577 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25636048 — Surrogate Endpoint (SUR): Bone mineral density
Study 25636048 — Surrogate Endpoint (SUR): Serum calcium
Study 21280197 — Predictive Biomarker (PRD): MTX3 mRNA
Genes: MTX3
Study 16776933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9754589 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7836943 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21302486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26464454 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 21472530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21472530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21472530 — Safety Biomarker (SAF): Interleukin 1
Study 16551312 — Surrogate Endpoint (SUR): Bone mineral density
Study 9640082 — Surrogate Endpoint (SUR): Serum creatinine
Study 29542334 — Safety Biomarker (SAF): Interleukin 1
Study 29542334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26534969 — Surrogate Endpoint (SUR): Blood pressure
Study 23109251 — Surrogate Endpoint (SUR): Bone mineral density
Study 16458213 — Surrogate Endpoint (SUR): Blood pressure
Study 14613739 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30570839 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21727201 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 21727201 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 17179200 — Surrogate Endpoint (SUR): Bone mineral density
Study 9678311 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 9678311 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 30504715 — Predictive Biomarker (PRD): Liver iron
Study 21158963 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 9534293 — Surrogate Endpoint (SUR): Blood pressure
Study 30676838 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27157293 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 14767877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14767877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7656832 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19539180 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19539180 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9480236 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 946973 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30811775 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24054187 — Surrogate Endpoint (SUR): Blood pressure
Study 29716702 — Surrogate Endpoint (SUR): Blood pressure
Study 22493422 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19087296 — Safety Biomarker (SAF): Hyaluronic acid
Study 30507731 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30507731 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28231831 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28231831 — Surrogate Endpoint (SUR): Blood pressure
Study 9730996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23021205 — Surrogate Endpoint (SUR): Blood pressure
Study 15309392 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15309392 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23916488 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD