TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21508089 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 21508089 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 21508089 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 21508089 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 21508125 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 21508633 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21514658 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21518322 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 21518985 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21518985 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21524193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21524193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21524193 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21524299 — Surrogate Endpoint (SUR): Blood pressure
Study 21524299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21525172 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 21525850 — Predictive Biomarker (PRD): AQP1 mRNA
Genes: AQP1; CHIP28
Study 21527026 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21527026 — Safety Biomarker (SAF): Th2 cell
Study 21527065 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21527065 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 21527169 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 21531880 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21531880 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21533229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21533229 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21533229 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21540460 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 21540460 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 21540460 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 21540460 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21540460 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21544866 — Surrogate Endpoint (SUR): Serum calcium
Study 21546328 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 21546328 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 21546328 — Surrogate Endpoint (SUR): Blood pressure
Study 21548986 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21549867 — Surrogate Endpoint (SUR): Bone mineral density
Study 21551228 — Predictive Biomarker (PRD): Chromosome 5q
Study 21551511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21551511 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21551511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21551511 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21551511 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 21551511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21555610 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21555610 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21556142 — Predictive Biomarker (PRD): ENOSF1 mRNA
Genes: ENOSF1; RTS; TYMSAS
Study 21556142 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21556142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21556950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21558401 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 21558401 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 21558987 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 21558987 — Predictive Biomarker (PRD): Hormone receptor
Study 21562341 — Predictive Biomarker (PRD): SCNN1A mRNA
Genes: SCNN1A; SCNN1
Study 21562341 — Predictive Biomarker (PRD): SCNN1G mRNA
Genes: SCNN1G
Study 21562341 — Surrogate Endpoint (SUR): Blood pressure
Study 21566092 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 21566092 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 21569559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21569596 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 21570076 — Surrogate Endpoint (SUR): Blood pressure
Study 21586165 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 21586342 — Surrogate Endpoint (SUR): Blood pressure
Study 21586342 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21592984 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21593354 — Predictive Biomarker (PRD): FLVCR1 mRNA
Genes: FLVCR1; FLVCR
Study 21593354 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 21596084 — Predictive Biomarker (PRD): TLR5 mRNA
Genes: TLR5; TIL3
Study 21596084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21606412 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 21606412 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 21606412 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 21606542 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21606542 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21609134 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 21610204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21610204 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21612781 — Surrogate Endpoint (SUR): Serum creatinine
Study 21613261 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21623265 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 21623265 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21623649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21624046 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21624046 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21628633 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 21628721 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21631213 — Surrogate Endpoint (SUR): Blood pressure
Study 21632852 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21632852 — Predictive Biomarker (PRD): C-C motif chemokine 7
Genes: CCL7; MCP3; SCYA6; SCYA7
Study 21632852 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 21632852 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 21632852 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 21632852 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 21632855 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 21633906 — Predictive Biomarker (PRD): PMAIP1 mRNA
Genes: PMAIP1; NOXA
Study 21633906 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21635145 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21635145 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21635145 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21639407 — Surrogate Endpoint (SUR): Blood pressure
Study 21642514 — Surrogate Endpoint (SUR): Pathological complete response
Study 21642685 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 21646032 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21648284 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 21651873 — Surrogate Endpoint (SUR): Blood pressure
Study 21652249 — Surrogate Endpoint (SUR): Bone mineral density
Study 21653689 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 21653689 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 21653689 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 21659625 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21659657 — Predictive Biomarker (PRD): INTS12 mRNA
Genes: INTS12; PHF22; SBBI22
Study 21659657 — Predictive Biomarker (PRD): GSTCD mRNA
Genes: GSTCD
Study 21659657 — Predictive Biomarker (PRD): NPNT mRNA
Genes: NPNT; EGFL6L; POEM; UNQ295/PRO334
Study 21659657 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 21659657 — Predictive Biomarker (PRD): PPT2 mRNA
Genes: PPT2
Study 21659657 — Predictive Biomarker (PRD): ADAM19 mRNA
Genes: ADAM19; MLTNB; FKSG34
Study 21666249 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21667134 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 21668924 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21669404 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 21670448 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 21670448 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 21670448 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 21670448 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 21670448 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 21670448 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 21670448 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study 21670448 — Predictive Biomarker (PRD): BAALC mRNA
Genes: BAALC
Study 21670448 — Predictive Biomarker (PRD): MECOM mRNA
Genes: MECOM; EVI1; MDS1; PRDM3
Study 21670448 — Predictive Biomarker (PRD): KMT2E mRNA
Genes: KMT2E; MLL5
Study 21670449 — Surrogate Endpoint (SUR): Hematologic response
Study 21673350 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 21674002 — Predictive Biomarker (PRD): GCKR mRNA
Genes: GCKR
Study 21674002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21676042 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21676217 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 21676217 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21676217 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 21676217 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 21676222 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21676394 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21677057 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21677057 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21679735 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21680644 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21680850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21680946 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21685174 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 21685174 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21685540 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21689421 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 21694639 — Predictive Biomarker (PRD): PKHD1 mRNA
Genes: PKHD1; FCYT; TIGM1
Study 21696575 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 21699369 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21699369 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21699369 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21700776 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study 21701566 — Predictive Biomarker (PRD): ACACB mRNA
Genes: ACACB; ACC2; ACCB
Study 21701566 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 21701566 — Predictive Biomarker (PRD): NKRF mRNA
Genes: NKRF; ITBA4; NRF
Study 21701566 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 21701807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21701807 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21704134 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21704134 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21704134 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21704134 — Safety Biomarker (SAF): BDNF
Study 21704784 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 21704887 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21704964 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21706288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21706316 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21706316 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 21712287 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21714604 — Surrogate Endpoint (SUR): Blood pressure
Study 21716163 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 21716260 — Surrogate Endpoint (SUR): Serum creatinine
Study 21716303 — Safety Biomarker (SAF): Fibroblast growth factor 1
Genes: FGF1
Study 21719129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21719124 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 21719418 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 21719884 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 21725047 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 21725050 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 21725050 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 21729182 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 21729732 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21730256 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21730256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21730256 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21730256 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21730256 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21730256 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 21730256 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21733227 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21733227 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 21733227 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 21733227 — Safety Biomarker (SAF): BDNF
Study 21733477 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 21735145 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21735145 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21737309 — Surrogate Endpoint (SUR): Blood pressure
Study 21738597 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21738597 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 21740673 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21741058 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21749698 — Predictive Biomarker (PRD): XRCC3 mRNA
Genes: XRCC3
Study 21749698 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 21749698 — Predictive Biomarker (PRD): GSTA1 mRNA
Genes: GSTA1
Study 21749698 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study 21752435 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 21752435 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 21752947 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21755013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21756035 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 21756035 — Predictive Biomarker (PRD): CLEC4D mRNA
Genes: CLEC4D; CLECSF8; MCL
Study 21756320 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21757572 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21757586 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21757630 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21757643 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21757643 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21760886 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 21761342 — Surrogate Endpoint (SUR): Serum testosterone
Study 21762873 — Surrogate Endpoint (SUR): Blood pressure
Study 21763168 — Predictive Biomarker (PRD): CPT1A mRNA
Genes: CPT1A; CPT1
Study 21763168 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21763653 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21764499 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 21764499 — Surrogate Endpoint (SUR): Blood pressure
Study 21765124 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21767228 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 21767331 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study 21767331 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21769849 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21772051 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21775114 — Predictive Biomarker (PRD): OLR1 mRNA
Genes: OLR1; CLEC8A; LOX1
Study 21775114 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21777076 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21777890 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 21778257 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21778257 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21782507 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21782507 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21782507 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 21784508 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 21787417 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 21787417 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21787417 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21791058 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21791415 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 21791415 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21791469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 21791513 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 21791540 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21791540 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21791540 — Surrogate Endpoint (SUR): Serum creatinine
Study 21791546 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21791546 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 21791546 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 21791546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21791591 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21791687 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 21794906 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 21794906 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 21799175 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21799175 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 21802835 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 21802881 — Surrogate Endpoint (SUR): Blood pressure
Study 21803569 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21804667 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT