TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25666295 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25666295 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 21857944 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21857944 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21857944 — Surrogate Endpoint (SUR): Blood pressure
Study 19039620 — Surrogate Endpoint (SUR): Blood pressure
Study 26330412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26330412 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8824693 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8824693 — Surrogate Endpoint (SUR): Blood pressure
Study 30964824 — Surrogate Endpoint (SUR): Blood pressure
Study 20949133 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20949133 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 20949133 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 20949133 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20949133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16263208 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29107562 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19188504 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 23211335 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 23211335 — Surrogate Endpoint (SUR): Serum calcium
Study 19456248 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19456248 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12482562 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12482562 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 12482562 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3298387 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29193662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30944029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30944029 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22298600 — Surrogate Endpoint (SUR): Blood pressure
Study 27255456 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15958836 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7674270 — Surrogate Endpoint (SUR): Blood pressure
Study 29154056 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29154056 — Surrogate Endpoint (SUR): Blood pressure
Study 23611083 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21936251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21936251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29318860 — Surrogate Endpoint (SUR): Blood pressure
Study 21817116 — Predictive Biomarker (PRD): BBC3 mRNA
Genes: BBC3; PUMA
Study 21817116 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 14976885 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 25524543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21360924 — Predictive Biomarker (PRD): SERPINF2 mRNA
Genes: SERPINF2; AAP; PLI
Study 16281491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10464060 — Surrogate Endpoint (SUR): Blood pressure
Study 2210987 — Surrogate Endpoint (SUR): Serum creatinine
Study 2210987 — Surrogate Endpoint (SUR): Blood pressure
Study 2210987 — Surrogate Endpoint (SUR): Serum potassium
Study 26683599 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18410584 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15838561 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15838561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12000008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12000008 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 12000008 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12000008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8670316 — Safety Biomarker (SAF): Interleukin 1
Study 8670316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30632413 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 6835735 — Surrogate Endpoint (SUR): Blood pressure
Study 18670735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2883908 — Surrogate Endpoint (SUR): Blood pressure
Study 25388906 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 9458147 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24799686 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19902046 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16909188 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 15072506 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 15072506 — Surrogate Endpoint (SUR): Serum creatinine
Study 23744513 — Surrogate Endpoint (SUR): Bone mineral density
Study 30699039 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 2826066 — Surrogate Endpoint (SUR): Blood pressure
Study 28629344 — Surrogate Endpoint (SUR): Bone mineral density
Study 23647406 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16776894 — Surrogate Endpoint (SUR): Blood pressure
Study 12830438 — Surrogate Endpoint (SUR): Blood pressure
Study 1588829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27061991 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12449158 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21400790 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 25778445 — Surrogate Endpoint (SUR): Blood pressure
Study 25778445 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31015098 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22313171 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22313171 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10480508 — Surrogate Endpoint (SUR): Blood pressure
Study 30957443 — Surrogate Endpoint (SUR): Blood pressure
Study 26003804 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23172931 — Surrogate Endpoint (SUR): Blood pressure
Study 19366957 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 19366957 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8102918 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 25519029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25519029 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 20025554 — Surrogate Endpoint (SUR): Blood pressure
Study 15946554 — Monitoring Biomarker (MOI): HBV DNA
Study 10388978 — Surrogate Endpoint (SUR): Blood pressure
Study 11803613 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7870633 — Surrogate Endpoint (SUR): Blood pressure
Study 2846455 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12450711 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 2285584 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31884320 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 10566550 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 6185788 — Surrogate Endpoint (SUR): Blood pressure
Study 28107276 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 28107276 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26253567 — Surrogate Endpoint (SUR): Blood pressure
Study 18051724 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18051724 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 18051724 — Surrogate Endpoint (SUR): Blood pressure
Study 16052334 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 11985388 — Predictive Biomarker (PRD): CACNA1A mRNA
Genes: CACNA1A; CACH4; CACN3; CACNL1A4
Study 8545141 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 1901528 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19403719 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 15459610 — Safety Biomarker (SAF): Reactive oxygen species
Study 10363944 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 26156073 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 24447434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 24447434 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 24447434 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10211629 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 14680725 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17361522 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11712434 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8805994 — Surrogate Endpoint (SUR): Serum calcium
Study 19115636 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11369627 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12881348 — Surrogate Endpoint (SUR): Blood pressure
Study 27009515 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18534276 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18534276 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 18534276 — Surrogate Endpoint (SUR): Blood pressure
Study 12459658 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 23285026 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 11807777 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 11807777 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 30043934 — Safety Biomarker (SAF): Interleukin 1
Study 19819486 — Surrogate Endpoint (SUR): Blood pressure
Study 16875159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16875159 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 16875159 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16875159 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12499050 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 17445831 — Surrogate Endpoint (SUR): Blood pressure
Study 2705441 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30552937 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30882476 — Surrogate Endpoint (SUR): Serum creatinine
Study 3524929 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 3524929 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 25796146 — Surrogate Endpoint (SUR): Blood pressure
Study 9186252 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 4026357 — Surrogate Endpoint (SUR): Serum sodium
Study 26811189 — Surrogate Endpoint (SUR): Blood pressure
Study 18390395 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18390395 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 18390395 — Surrogate Endpoint (SUR): Blood pressure
Study 12657405 — Surrogate Endpoint (SUR): Blood pressure
Study 11271340 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 29504187 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 27599039 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 25409371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15975977 — Surrogate Endpoint (SUR): Blood pressure
Study 8828788 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 8828788 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28084062 — Surrogate Endpoint (SUR): Bone mineral density
Study 20938662 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 11398878 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8584300 — Surrogate Endpoint (SUR): Bone mineral density
Study 2127076 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 28681205 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8845601 — Surrogate Endpoint (SUR): Bone mineral density
Study 8845601 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23748166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22002336 — Surrogate Endpoint (SUR): Blood pressure
Study 11751715 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11751715 — Surrogate Endpoint (SUR): Blood pressure
Study 2884059 — Surrogate Endpoint (SUR): Blood pressure
Study 29680006 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18573839 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 16095053 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10599951 — Surrogate Endpoint (SUR): Blood pressure
Study 30784924 — Predictive Biomarker (PRD): Activated leukocyte cell adhesionmolecule
Genes: ALCAM; MEMD
Study 15741208 — Surrogate Endpoint (SUR): Serum creatinine
Study 8491498 — Surrogate Endpoint (SUR): Blood pressure
Study 30378311 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30378311 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12865102 — Surrogate Endpoint (SUR): Serum potassium
Study 10805059 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 8644690 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 8644690 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27605407 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 16085556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10707784 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 11836286 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11836286 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10094169 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23906938 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23906938 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19728118 — Surrogate Endpoint (SUR): Bone mineral density
Study 9692412 — Surrogate Endpoint (SUR): Blood pressure
Study 2468862 — Surrogate Endpoint (SUR): Blood pressure
Study 30554386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30554386 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27832384 — Surrogate Endpoint (SUR): Serum uric acid
Study 25963425 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 18038208 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 16839319 — Predictive Biomarker (PRD): MC3R mRNA
Genes: MC3R
Study 10636260 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25669177 — Surrogate Endpoint (SUR): Blood pressure
Study 25669177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18344711 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11208501 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27334434 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 27334434 — Predictive Biomarker (PRD): SLC2A1 mRNA
Genes: SLC2A1; GLUT1
Study 9141121 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29047215 — Surrogate Endpoint (SUR): Blood pressure
Study 18447091 — Surrogate Endpoint (SUR): Blood pressure
Study 7649339 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1106204 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 1421390 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29767227 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 25719344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25719344 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 20869358 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 17030751 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 15895715 — Predictive Biomarker (PRD): ALAS2 mRNA
Genes: ALAS2; ALASE; ASB
Study 7699233 — Surrogate Endpoint (SUR): Plasma ammonia
Study 21633719 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 1790087 — Predictive Biomarker (PRD): PLAGL1 mRNA
Genes: PLAGL1; LOT1; ZAC
Study 1790087 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 20579524 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 1816597 — Surrogate Endpoint (SUR): Blood pressure
Study 23055587 — Surrogate Endpoint (SUR): Bacterial count
Study 15811060 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15811060 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29726480 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29726480 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20670466 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20670466 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17695946 — Surrogate Endpoint (SUR): Blood pressure
Study 15805229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7506172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7506172 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7506172 — Surrogate Endpoint (SUR): Blood pressure
Study 31268481 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21660675 — Surrogate Endpoint (SUR): Blood pressure
Study 21660675 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 14751651 — Surrogate Endpoint (SUR): Blood pressure
Study 3575022 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7974348 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7974348 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2493869 — Surrogate Endpoint (SUR): Blood pressure
Study 30668274 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 28526798 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8772223 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30459099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26599332 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study 21182345 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 12535809 — Surrogate Endpoint (SUR): Blood pressure
Study 25277543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19129262 — Surrogate Endpoint (SUR): Blood pressure
Study 12684358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12684358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12684358 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 12684358 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 12684358 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1524994 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31587925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29509769 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 18593651 — Surrogate Endpoint (SUR): Blood pressure
Study 3989392 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31504118 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 28747330 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28747330 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15365277 — Surrogate Endpoint (SUR): Blood pressure
Study 27137950 — Surrogate Endpoint (SUR): Blood pressure
Study 22192144 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 20430947 — Predictive Biomarker (PRD): TNF-related weak inducer of apoptosis
Genes: TNFSF12; APO3L; DR3LG; UNQ181/PRO207
Study 20430947 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 11966765 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 11966765 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30875097 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30875097 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10451461 — Surrogate Endpoint (SUR): Serum calcium
Study 10451461 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2141491 — Surrogate Endpoint (SUR): Blood pressure
Study 2141491 — Surrogate Endpoint (SUR): Serum creatinine
Study 695649 — Surrogate Endpoint (SUR): Blood pressure
Study 19690349 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15550144 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4