TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9597405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2643934 — Surrogate Endpoint (SUR): Blood pressure
Study 18502235 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2252771 — Surrogate Endpoint (SUR): Blood pressure
Study 31425577 — Surrogate Endpoint (SUR): Serum testosterone
Study 28558718 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18978628 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9226551 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 22445776 — Safety Biomarker (SAF): DRD3
Study 24605899 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9701186 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 7917149 — Surrogate Endpoint (SUR): Blood pressure
Study 24459762 — Surrogate Endpoint (SUR): Serum calcium
Study 22196471 — Surrogate Endpoint (SUR): Blood pressure
Study 12494116 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2758767 — Surrogate Endpoint (SUR): Serum calcium
Study 2758767 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17894827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15319390 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 15319390 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15319390 — Predictive Biomarker (PRD): KLRD1 mRNA
Genes: KLRD1; CD94
Study 16051891 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12103384 — Safety Biomarker (SAF): Urinary microalbumin
Study 7476052 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18362294 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2162437 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 2162437 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 31511288 — Surrogate Endpoint (SUR): Blood pressure
Study 26255794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23073216 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8488694 — Surrogate Endpoint (SUR): Blood pressure
Study 23129412 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 23129412 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 23129412 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20118767 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17058823 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 17058823 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17058823 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12730149 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10391422 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10391422 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19050388 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19548437 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 14707013 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9432096 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15929052 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 15761783 — Safety Biomarker (SAF): Reactive oxygen species
Study 12847065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22119634 — Surrogate Endpoint (SUR): Blood pressure
Study 19221727 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 28264429 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25835492 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28103427 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20852871 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20852871 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 19014770 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26387946 — Predictive Biomarker (PRD): JAG1 mRNA
Genes: JAG1; JAGL1
Study 26387946 — Predictive Biomarker (PRD): NOTCH4 mRNA
Genes: NOTCH4; INT3
Study 26387946 — Predictive Biomarker (PRD): ALDH1A1 mRNA
Genes: ALDH1A1; ALDC; ALDH1; PUMB1
Study 23750462 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 11574180 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30209561 — Predictive Biomarker (PRD): MINPP1 mRNA
Genes: MINPP1; MIPP; UNQ900/PRO1917
Study 30209561 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 10322817 — Surrogate Endpoint (SUR): Blood pressure
Study 27974311 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26654448 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15136972 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15136972 — Surrogate Endpoint (SUR): Blood pressure
Study 11591569 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22648717 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 20614483 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 17244352 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 17244352 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17244352 — Predictive Biomarker (PRD): SULT1A1 mRNA
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 17244352 — Predictive Biomarker (PRD): UGT2B15 mRNA
Genes: UGT2B15; UGT2B8
Study 15998903 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15998903 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7486178 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21396307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21396307 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 21396307 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21396307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21396307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16550733 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16550733 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10880410 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10880410 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20401689 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 20401689 — Predictive Biomarker (PRD): ADRB3 mRNA
Genes: ADRB3; ADRB3R; B3AR
Study 20401689 — Predictive Biomarker (PRD): ADRA2B mRNA
Genes: ADRA2B; ADRA2L1; ADRA2RL1
Study 11754126 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 9249234 — Surrogate Endpoint (SUR): Blood pressure
Study 9797854 — Safety Biomarker (SAF): PPOX
Genes: HCRT; OX
Study 25872588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17028986 — Surrogate Endpoint (SUR): Bone mineral density
Study 10392868 — Surrogate Endpoint (SUR): Blood pressure
Study 10392868 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10392868 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21470388 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 29543933 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25288473 — Predictive Biomarker (PRD): NAIP mRNA
Genes: NAIP; BIRC1
Study 25288473 — Predictive Biomarker (PRD): GDF9 mRNA
Genes: GDF9
Study 22712670 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22712670 — Surrogate Endpoint (SUR): Blood pressure
Study 11748093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9291905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9291905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25725192 — Surrogate Endpoint (SUR): Blood pressure
Study 19358785 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 19643661 — Surrogate Endpoint (SUR): Blood pressure
Study 19643661 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15164108 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 2561145 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2561145 — Surrogate Endpoint (SUR): Blood pressure
Study 31238961 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 31238961 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19842887 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 17030532 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11352132 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 27407018 — Predictive Biomarker (PRD): SLC22A1 mRNA
Genes: SLC22A1; OCT1
Study 28336242 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 28336242 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 23216707 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 27030352 — Surrogate Endpoint (SUR): Blood pressure
Study 18264992 — Predictive Biomarker (PRD): NELFE mRNA
Genes: NELFE; RD; RDBP
Study 25139208 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20550764 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10579472 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10579472 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10579472 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 572996 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20110022 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20110022 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18003666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12909221 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 8886549 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2037068 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DAND5 mRNA
Genes: DAND5; CER2; CKTSF1B3; GREM3; SP1
Study 6132082 — Surrogate Endpoint (SUR): Blood pressure
Study 21081550 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10562937 — Surrogate Endpoint (SUR): Blood pressure
Study 17952842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17952842 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12169865 — Surrogate Endpoint (SUR): Blood pressure
Study 12082498 — Surrogate Endpoint (SUR): Blood pressure
Study 29746150 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 23588309 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 20367136 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 368538 — Surrogate Endpoint (SUR): Blood pressure
Study 23010344 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 20597872 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11041314 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31285357 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 11853795 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 7670005 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28449320 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 3593990 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19436693 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9508204 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31850603 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 29099972 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 19154992 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 17216347 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 31554005 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 18083750 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18083750 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6254720 — Surrogate Endpoint (SUR): Blood pressure
Study 25012765 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20483042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20483042 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study 20483042 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20483042 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 11247401 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18645193 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 18645193 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 18645193 — Surrogate Endpoint (SUR): Serum testosterone
Study 18645193 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 12877888 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12877888 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12877888 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10360185 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7740525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19927011 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19927011 — Surrogate Endpoint (SUR): Blood pressure
Study 10334524 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 8960857 — Surrogate Endpoint (SUR): Blood pressure
Study 8960857 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1661765 — Surrogate Endpoint (SUR): Blood pressure
Study 23257098 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20854139 — Surrogate Endpoint (SUR): Blood pressure
Study 12077744 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9596232 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27356083 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 12360175 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12360175 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12360175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10432959 — Surrogate Endpoint (SUR): Bone mineral density
Study 19679248 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19679248 — Surrogate Endpoint (SUR): Blood pressure
Study 15051598 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 20205646 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 2120785 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16487501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16487501 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8155388 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8155388 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3279769 — Surrogate Endpoint (SUR): Bone mineral density
Study 24997863 — Surrogate Endpoint (SUR): Blood pressure
Study 19929694 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19929694 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2024567 — Surrogate Endpoint (SUR): Serum potassium
Study 7740465 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 2965633 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2965633 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 23235922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23235922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23235922 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23235922 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10627439 — Surrogate Endpoint (SUR): Serum creatinine
Study 10627439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10627439 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 12185402 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 12185402 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30942613 — Predictive Biomarker (PRD): CIB1 mRNA
Genes: CIB1; CIB; KIP; PRKDCIP
Study 30942613 — Pharmacodynamic Biomarker (PDY): Cyclin-dependent kinase 1
Genes: CDK1; CDC2; CDC28A; CDKN1; P34CDC2
Study 30942613 — Surrogate Endpoint (SUR): Sperm parameters
Study 16928473 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 8457776 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2878175 — Surrogate Endpoint (SUR): Blood pressure
Study 29356462 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19804441 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10715760 — Surrogate Endpoint (SUR): Blood pressure
Study 7150458 — Surrogate Endpoint (SUR): Blood pressure
Study 24449558 — Surrogate Endpoint (SUR): Blood pressure
Study 16400465 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8103382 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 25398670 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 12953145 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29769060 — Safety Biomarker (SAF): Hyaluronic acid
Study 17176801 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9867068 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21733413 — Surrogate Endpoint (SUR): Blood pressure
Study 21733413 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21733413 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15798822 — Predictive Biomarker (PRD): SESTD1 mRNA
Genes: SESTD1; SOLO
Study 8586807 — Surrogate Endpoint (SUR): Blood pressure
Study 23329881 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17277036 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30997730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30997730 — Surrogate Endpoint (SUR): Blood pressure
Study 28035016 — Surrogate Endpoint (SUR): Blood pressure
Study 26165688 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 26165688 — Predictive Biomarker (PRD): Tubulin beta-3 chain
Genes: TUBB3; TUBB4
Study 23475823 — Surrogate Endpoint (SUR): Blood pressure
Study 1586061 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 12099160 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12099160 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12099160 — Surrogate Endpoint (SUR): Blood pressure
Study 31055875 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 17914548 — Surrogate Endpoint (SUR): Blood pressure
Study 8442918 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19171004 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 25942434 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29735587 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20035347 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31980201 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study 25888246 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25888246 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25888246 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 25888246 — Predictive Biomarker (PRD): Hormone receptor
Study 25888246 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9004827 — Surrogate Endpoint (SUR): Blood pressure
Study 28881339 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 26314293 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 11037800 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30571591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30571591 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27982160 — Surrogate Endpoint (SUR): Blood pressure
Study 26234491 — Safety Biomarker (SAF): Hyaluronic acid
Study 11719836 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31544950 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 31544950 — Safety Biomarker (SAF): BDNF
Study 19700948 — Surrogate Endpoint (SUR): Blood pressure
Study 15307699 — Surrogate Endpoint (SUR): Blood pressure
Study 11175492 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11175492 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3667024 — Surrogate Endpoint (SUR): Blood pressure
Study 30152415 — Surrogate Endpoint (SUR): Blood pressure
Study 23277307 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 21623673 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16492920 — Predictive Biomarker (PRD): XPC mRNA
Genes: XPC; XPCC
Study 16492920 — Predictive Biomarker (PRD): RAD23B mRNA
Genes: RAD23B
Study 16492920 — Predictive Biomarker (PRD): ERCC6 mRNA
Genes: ERCC6
Study 16492920 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC