TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23584298 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23584298 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23584298 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21697819 — Surrogate Endpoint (SUR): Blood pressure
Study 21697819 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14748761 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 29454501 — Predictive Biomarker (PRD): TREM1 mRNA
Genes: TREM1
Study 29454501 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 25402403 — Surrogate Endpoint (SUR): Blood pressure
Study 26051567 — Surrogate Endpoint (SUR): Blood pressure
Study 24016218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8790569 — Monitoring Biomarker (MOI): HBV DNA
Study 30503831 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30503831 — Monitoring Biomarker (MOI): miR-145-5p
Genes: MIR145
Study 30503831 — Safety Biomarker (SAF): miR-192-5p
Genes: MIR192
Study 30503831 — Safety Biomarker (SAF): miR-192
Genes: MIR192
Study 30503831 — Monitoring Biomarker (MOI): miR-195-5p
Genes: MIR195
Study 30503831 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-320b
Study 18063399 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 18063399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15580349 — Surrogate Endpoint (SUR): Bone mineral density
Study 12841703 — Surrogate Endpoint (SUR): Blood pressure
Study 27647071 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9764720 — Surrogate Endpoint (SUR): Blood pressure
Study 25124303 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 18071731 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18071731 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11835076 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11835076 — Surrogate Endpoint (SUR): Blood pressure
Study 27386641 — Monitoring Biomarker (MOI): HBV DNA
Study 23189083 — Surrogate Endpoint (SUR): Blood pressure
Study 23189083 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28945060 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28945060 — Safety Biomarker (SAF): Interleukin 1
Study 28945060 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28945060 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14565594 — Surrogate Endpoint (SUR): Bone mineral density
Study 11230031 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 7684457 — Surrogate Endpoint (SUR): Blood pressure
Study 31670794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18334815 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9322828 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9322828 — Surrogate Endpoint (SUR): Blood pressure
Study 7690462 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22218122 — Surrogate Endpoint (SUR): Serum creatinine
Study 31821349 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 24528686 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24528686 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17621463 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17621463 — Surrogate Endpoint (SUR): Bone mineral density
Study 236810 — Surrogate Endpoint (SUR): Blood pressure
Study 30853361 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 25774838 — Surrogate Endpoint (SUR): Blood pressure
Study 19084016 — Monitoring Biomarker (MOI): HBV DNA
Study 16915367 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 10598606 — Surrogate Endpoint (SUR): Blood pressure
Study 24066672 — Surrogate Endpoint (SUR): Blood pressure
Study 21852698 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 29141719 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 23965321 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 14707788 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11595607 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27638847 — Surrogate Endpoint (SUR): Blood pressure
Study 16478814 — Surrogate Endpoint (SUR): Bone mineral density
Study 28368521 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28368521 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 28368521 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 28005440 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9538647 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 18701642 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 12818461 — Surrogate Endpoint (SUR): Bone mineral density
Study 10083765 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10083765 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7729302 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23505172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23505172 — Surrogate Endpoint (SUR): Blood pressure
Study 23505172 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7218393 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7881645 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2364920 — Surrogate Endpoint (SUR): Blood pressure
Study 31099188 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 31099188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31099188 — Surrogate Endpoint (SUR): Bone mineral density
Study 31099188 — Surrogate Endpoint (SUR): Blood pressure
Study 28364091 — Surrogate Endpoint (SUR): Blood pressure
Study 21480207 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 21480207 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 14736627 — Surrogate Endpoint (SUR): Bone mineral density
Study 8035590 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8035590 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 8035590 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 8035590 — Surrogate Endpoint (SUR): Blood pressure
Study 23395779 — Surrogate Endpoint (SUR): Blood pressure
Study 12653877 — Surrogate Endpoint (SUR): Blood pressure
Study 19786378 — Safety Biomarker (SAF): RYR1
Genes: RYR; PPP1R137
Study 19786378 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19786378 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15577134 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18258639 — Surrogate Endpoint (SUR): Bone mineral density
Study 16377385 — Surrogate Endpoint (SUR): Serum uric acid
Study 16377385 — Surrogate Endpoint (SUR): Blood pressure
Study 16377385 — Surrogate Endpoint (SUR): Serum creatinine
Study 7886558 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2429076 — Surrogate Endpoint (SUR): Blood pressure
Study 15706463 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 29249583 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29249583 — Surrogate Endpoint (SUR): Blood pressure
Study 21963214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8540713 — Surrogate Endpoint (SUR): Serum creatinine
Study 7794079 — Predictive Biomarker (PRD): TICAM2 mRNA
Genes: TICAM2; TIRAP3; TIRP; TRAM
Study 22795617 — Predictive Biomarker (PRD): IRF1 mRNA
Genes: IRF1
Study 11682661 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11682661 — Surrogate Endpoint (SUR): Serum creatinine
Study 28807030 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 14973088 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 30882151 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 30882151 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 30882151 — Predictive Biomarker (PRD): CHRNB4 mRNA
Genes: CHRNB4
Study 24758521 — Predictive Biomarker (PRD): ERF mRNA
Genes: ERF
Study 20160655 — Surrogate Endpoint (SUR): Blood pressure
Study 31078191 — Predictive Biomarker (PRD): CCNP mRNA
Genes: CCNP; CNTD2
Study 23536583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23536583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23536583 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18810398 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17971947 — Monitoring Biomarker (MOI): HBV DNA
Study 11368294 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28378467 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 21500996 — Surrogate Endpoint (SUR): Bone mineral density
Study 29868911 — Surrogate Endpoint (SUR): Blood pressure
Study 26940938 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23553866 — Surrogate Endpoint (SUR): Bone mineral density
Study 7786658 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7786658 — Surrogate Endpoint (SUR): Blood pressure
Study 11737400 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11737400 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12750166 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 12750166 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 12750166 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1514500 — Surrogate Endpoint (SUR): Blood pressure
Study 31448837 — Surrogate Endpoint (SUR): Probing pocket depth
Study 2220176 — Predictive Biomarker (PRD): Hormone receptor
Study 730416 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 30626425 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 30626425 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30626425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30626425 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 17397559 — Predictive Biomarker (PRD): FURIN mRNA
Genes: FURIN; FUR; PACE; PCSK3
Study 16619162 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28191913 — Surrogate Endpoint (SUR): Blood pressure
Study 31068943 — Safety Biomarker (SAF): miR-181a
Study 31068943 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 31068943 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 31068943 — Predictive Biomarker (PRD): miR-181a-5p
Study 26367500 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 26367500 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 26367500 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 26367500 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 26367500 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 26367500 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 26367500 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 31711219 — Surrogate Endpoint (SUR): Blood pressure
Study 21760473 — Surrogate Endpoint (SUR): Blood pressure
Study 21760473 — Surrogate Endpoint (SUR): Serum creatinine
Study 19641358 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 15894896 — Surrogate Endpoint (SUR): Blood pressure
Study 6804625 — Surrogate Endpoint (SUR): Blood pressure
Study 30213052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30213052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22323869 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20661198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23097096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19108988 — Surrogate Endpoint (SUR): Blood pressure
Study 17209672 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17209672 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 17209672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17209672 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17209672 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3415889 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8498894 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31787433 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 31445354 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29234057 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23401618 — Surrogate Endpoint (SUR): Blood pressure
Study 15955900 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22901697 — Surrogate Endpoint (SUR): Blood pressure
Study 22901697 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 12390425 — Surrogate Endpoint (SUR): Serum creatinine
Study 12390425 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 7739278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7739278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1697283 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11792333 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11792333 — Surrogate Endpoint (SUR): Blood pressure
Study 10069784 — Surrogate Endpoint (SUR): Blood pressure
Study 30985704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30985704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26691413 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26691413 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22198452 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC18A2 mRNA
Genes: SLC18A2; SVMT; VMAT2
Study 20633266 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20633266 — Surrogate Endpoint (SUR): Blood pressure
Study 17414459 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29288137 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27382816 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27382816 — Surrogate Endpoint (SUR): Blood pressure
Study 25801892 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25801892 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 25801892 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 10808170 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8497871 — Surrogate Endpoint (SUR): Serum creatinine
Study 15728401 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15728401 — Surrogate Endpoint (SUR): Blood pressure
Study 15728401 — Surrogate Endpoint (SUR): Serum creatinine
Study 24266780 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28039505 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 22674191 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 22674191 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31331572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28434633 — Surrogate Endpoint (SUR): Blood pressure
Study 28434633 — Surrogate Endpoint (SUR): Serum testosterone
Study 24922664 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 17198918 — Surrogate Endpoint (SUR): Blood pressure
Study 16651204 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31101184 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31101184 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28175316 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 25533774 — Surrogate Endpoint (SUR): Blood pressure
Study 17053058 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11991446 — Surrogate Endpoint (SUR): Bone mineral density
Study 2550634 — Surrogate Endpoint (SUR): Blood pressure
Study 31183442 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 10528662 — Surrogate Endpoint (SUR): Blood pressure
Study 31162597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31162597 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 31162597 — Surrogate Endpoint (SUR): Blood pressure
Study 20051095 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11505129 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23828160 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10856733 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10856733 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9062490 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22821660 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22821660 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 26546612 — Predictive Biomarker (PRD): AZGP1 mRNA
Genes: AZGP1; ZAG; ZNGP1
Study 26546612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26546612 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18294333 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8706775 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 31689118 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12575232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30829619 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 28301671 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 28301671 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 12603713 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28280319 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 19449756 — Surrogate Endpoint (SUR): Blood pressure
Study 12357478 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9681285 — Surrogate Endpoint (SUR): Blood pressure
Study 8006886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19167078 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 29238675 — Surrogate Endpoint (SUR): Blood pressure
Study 20653677 — Surrogate Endpoint (SUR): Serum creatinine
Study 18662152 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 9405024 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9405024 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3450521 — Surrogate Endpoint (SUR): Blood pressure
Study 30873633 — Safety Biomarker (SAF): L-acetylcarnitine
Study 30873633 — Surrogate Endpoint (SUR): Sperm parameters
Study 2891531 — Surrogate Endpoint (SUR): Blood pressure
Study 31015068 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29023319 — Surrogate Endpoint (SUR): Blood pressure
Study 19783714 — Surrogate Endpoint (SUR): Plasma methotrexate
Study 11103749 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 1473073 — Surrogate Endpoint (SUR): Serum testosterone
Study 6702646 — Surrogate Endpoint (SUR): Blood pressure
Study 31205087 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15589006 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9028689 — Surrogate Endpoint (SUR): Blood pressure
Study 9028689 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23253702 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20855671 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 16884979 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9287446 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16936417 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12968843 — Surrogate Endpoint (SUR): Serum sodium
Study 8707483 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8707483 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 1514711 — Surrogate Endpoint (SUR): Blood pressure
Study 6096193 — Surrogate Endpoint (SUR): Blood pressure
Study 24383508 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24383508 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20851295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 7235806 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24903195 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 7848022 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein