TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27958255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16340523 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 28114928 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 14624050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14624050 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9200390 — Surrogate Endpoint (SUR): Blood pressure
Study 26786576 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26786576 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24770617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 11897925 — Surrogate Endpoint (SUR): Blood pressure
Study 7148839 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25401456 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 19441869 — Predictive Biomarker (PRD): PEBP1 mRNA
Genes: PEBP1; PBP; PEBP
Study 9360143 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 24421289 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 16483699 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16231622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16231622 — Safety Biomarker (SAF): Interleukin 1
Study 16231622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16231622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7788039 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7788039 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7788039 — Surrogate Endpoint (SUR): Blood pressure
Study 12097666 — Surrogate Endpoint (SUR): Blood pressure
Study 2108908 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11872106 — Surrogate Endpoint (SUR): Blood pressure
Study 3134397 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29438092 — Predictive Biomarker (PRD): EGFL7 mRNA
Genes: EGFL7; MEGF7; UNQ187/PRO1449
Study 29438092 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27374839 — Surrogate Endpoint (SUR): Serum creatinine
Study 22410113 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 7778170 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 7778170 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7778170 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 21036355 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16351564 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17251695 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 10937517 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 1353350 — Surrogate Endpoint (SUR): Blood pressure
Study 31179743 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 31179743 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PLA2G5 mRNA
Genes: PLA2G5
Study 24989892 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24989892 — Predictive Biomarker (PRD): FCGR2A mRNA
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 24989892 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 24989892 — Predictive Biomarker (PRD): FCGR2B mRNA
Genes: FCGR2B; CD32; FCG2; IGFR2
Study 1993497 — Monitoring Biomarker (MOI): HBV DNA
Study 23624296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23624296 — Predictive Biomarker (PRD): HNF4A mRNA
Genes: HNF4A; HNF4; NR2A1; TCF14
Study 23624296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11549629 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11549629 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11549629 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7785133 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 28872526 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 2446078 — Surrogate Endpoint (SUR): Blood pressure
Study 26036434 — Surrogate Endpoint (SUR): Bone mineral density
Study 15066931 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29160303 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 29160303 — Predictive Biomarker (PRD): TM6SF2 mRNA
Genes: TM6SF2
Study 29160303 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28945881 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 28945881 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 8467321 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23233650 — Predictive Biomarker (PRD): FOXM1 mRNA
Genes: FOXM1; FKHL16; HFH11; MPP2; WIN
Study 23233650 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23233650 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18636367 — Surrogate Endpoint (SUR): Blood pressure
Study 31755321 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 31755321 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 16544318 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12719802 — Safety Biomarker (SAF): Reactive oxygen species
Study 12719802 — Surrogate Endpoint (SUR): Serum creatinine
Study 31908438 — Surrogate Endpoint (SUR): Bone mineral density
Study 25431052 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 25431052 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 16917950 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 9251545 — Surrogate Endpoint (SUR): Blood pressure
Study 9251545 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23889039 — Surrogate Endpoint (SUR): Blood pressure
Study 11823753 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 2920503 — Surrogate Endpoint (SUR): Blood pressure
Study 27756322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22556178 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 22556178 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22556178 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22556178 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16152823 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16152823 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16152823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8993243 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8993243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8993243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8993243 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 8993243 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2962617 — Surrogate Endpoint (SUR): Blood pressure
Study 23725684 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 23725684 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17192957 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study 11170981 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31049139 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 31049139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 31049139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31049139 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31049139 — Safety Biomarker (SAF): Interleukin 1
Study 31049139 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 31049139 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28434116 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 28434116 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 28434116 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28434116 — Monitoring Biomarker (MOI): Procalcitonin
Study 25350981 — Surrogate Endpoint (SUR): Blood pressure
Study 23404689 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18581891 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 18581891 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 18581891 — Surrogate Endpoint (SUR): Bone mineral density
Study 18581891 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 18581891 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 18581891 — Surrogate Endpoint (SUR): Serum calcium
Study 10800798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10800798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10575530 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30420448 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 23478743 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18355658 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16736344 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14508028 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1360793 — Surrogate Endpoint (SUR): Blood pressure
Study 31366601 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 27138794 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22041458 — Predictive Biomarker (PRD): SACM1L mRNA
Genes: SACM1L; KIAA0851; SAC1
Study 22041458 — Predictive Biomarker (PRD): MAGI2 mRNA
Genes: MAGI2; ACVRINP1; AIP1; KIAA0705
Study 22041458 — Predictive Biomarker (PRD): WDFY4 mRNA
Genes: WDFY4; C10orf64; KIAA1607
Study 22041458 — Predictive Biomarker (PRD): CHL1 mRNA
Genes: CHL1; CALL
Study 19743503 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 11849464 — Surrogate Endpoint (SUR): Blood pressure
Study 15494430 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 12076551 — Surrogate Endpoint (SUR): Blood pressure
Study 7840291 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7840291 — Predictive Biomarker (PRD): ADCY10 mRNA
Genes: ADCY10; SAC
Study 7840291 — Surrogate Endpoint (SUR): Blood pressure
Study 1849532 — Surrogate Endpoint (SUR): Blood pressure
Study 23660849 — Surrogate Endpoint (SUR): Blood pressure
Study 9916609 — Surrogate Endpoint (SUR): Blood pressure
Study 7830855 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27798211 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23824420 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23824420 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23824420 — Surrogate Endpoint (SUR): Blood pressure
Study 26725406 — Surrogate Endpoint (SUR): Forced vital capacity
Study 13680555 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 13680555 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 13680555 — Surrogate Endpoint (SUR): Blood pressure
Study 19637650 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 19277899 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 15565824 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28572159 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 21533568 — Surrogate Endpoint (SUR): Blood pressure
Study 12577414 — Predictive Biomarker (PRD): ALPK1 mRNA
Genes: ALPK1; KIAA1527; LAK
Study 9442148 — Surrogate Endpoint (SUR): Serum creatinine
Study 3063783 — Surrogate Endpoint (SUR): Blood pressure
Study 30139780 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28031704 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 26336957 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26336957 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26336957 — Surrogate Endpoint (SUR): Blood pressure
Study 24565342 — Surrogate Endpoint (SUR): Blood pressure
Study 21779784 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21779784 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18626722 — Surrogate Endpoint (SUR): Blood pressure
Study 11155900 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24796937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24796937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28335413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19458139 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 11208838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31264770 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 21198740 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9873961 — Surrogate Endpoint (SUR): Blood pressure
Study 12836710 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25150116 — Surrogate Endpoint (SUR): Blood pressure
Study 9809932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9809932 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8689742 — Surrogate Endpoint (SUR): Probing pocket depth
Study 2667523 — Surrogate Endpoint (SUR): Blood pressure
Study 2667523 — Surrogate Endpoint (SUR): Serum sodium
Study 1934867 — Surrogate Endpoint (SUR): Blood pressure
Study 31161217 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31161217 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 335789 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 31441769 — Surrogate Endpoint (SUR): Blood pressure
Study 31441769 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26363409 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23474315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3908121 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22143221 — Surrogate Endpoint (SUR): Blood pressure
Study 9284853 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9284853 — Safety Biomarker (SAF): Interleukin 1
Study 9284853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31928523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31928523 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10955773 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 8694306 — Surrogate Endpoint (SUR): Blood pressure
Study 21095484 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30803542 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study 24338514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17518923 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 9704737 — Predictive Biomarker (PRD): ROPN1L mRNA
Genes: ROPN1L; ASP; RSPH11
Study 2480613 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 18614861 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15747448 — Surrogate Endpoint (SUR): Bone mineral density
Study 10520081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10520081 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12150629 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 7884424 — Surrogate Endpoint (SUR): Serum creatinine
Study 23506972 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 20629698 — Surrogate Endpoint (SUR): Serum potassium
Study 18714934 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7723663 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 23347259 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 16923414 — Surrogate Endpoint (SUR): Blood pressure
Study 9597417 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11691520 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2906018 — Surrogate Endpoint (SUR): Blood pressure
Study 30545242 — Safety Biomarker (SAF): Hyaluronic acid
Study 19139427 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 17198089 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17198089 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 17198089 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12140732 — Surrogate Endpoint (SUR): Blood pressure
Study 22540523 — Surrogate Endpoint (SUR): Blood pressure
Study 22540523 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22540523 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24453078 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 24453078 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 12804926 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 12804926 — Surrogate Endpoint (SUR): Blood pressure
Study 3905064 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 19857542 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10202575 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 28904053 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28904053 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16954712 — Surrogate Endpoint (SUR): Blood pressure
Study 30045336 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 30045336 — Surrogate Endpoint (SUR): Blood pressure
Study 30045336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23588255 — Safety Biomarker (SAF): IL-6 and IL-10
Study 20487410 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 1849160 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16556072 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29458407 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 24064461 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 8640295 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 29422384 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 23743811 — Surrogate Endpoint (SUR): Blood pressure
Study 16508131 — Surrogate Endpoint (SUR): Bone mineral density
Study 18484901 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12194927 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 7198413 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7198413 — Surrogate Endpoint (SUR): Blood pressure
Study 29166256 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 15543326 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9952092 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 25697217 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 19125992 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 1465079 — Surrogate Endpoint (SUR): Blood pressure
Study 25583761 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 18649055 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18649055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20160157 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16583990 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 16583990 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 12131102 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 19617879 — Surrogate Endpoint (SUR): Blood pressure
Study 2741218 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 22943577 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21431424 — Surrogate Endpoint (SUR): Blood pressure
Study 21431424 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17598639 — Surrogate Endpoint (SUR): Blood pressure
Study 29406853 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 25620436 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23725919 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12934464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12934464 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 12934464 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 10868643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10868643 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG