TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19614803 — Surrogate Endpoint (SUR): Blood pressure
Study 9660521 — Surrogate Endpoint (SUR): Blood pressure
Study 6945041 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30124941 — Surrogate Endpoint (SUR): Serum creatinine
Study 22097175 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15125032 — Surrogate Endpoint (SUR): Blood pressure
Study 6130244 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23204157 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23204157 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12850128 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 31049566 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 29500454 — Predictive Biomarker (PRD): PNPLA2 mRNA
Genes: PNPLA2; ATGL; FP17548
Study 23805175 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 12660520 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 29284427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29284427 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25706090 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25706090 — Safety Biomarker (SAF): BDNF
Study 20378644 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18777992 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 9431711 — Safety Biomarker (SAF): Hyaluronic acid
Study 25980298 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16898488 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8780660 — Surrogate Endpoint (SUR): Blood pressure
Study 1621675 — Surrogate Endpoint (SUR): Serum creatinine
Study 1621675 — Surrogate Endpoint (SUR): Blood pressure
Study 29894613 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 20838357 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 7662220 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7662220 — Surrogate Endpoint (SUR): Blood pressure
Study 7662220 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21851905 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 28654365 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 28654365 — Predictive Biomarker (PRD): Hormone receptor
Study 11773150 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30519766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30519766 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27798417 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19038356 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16886330 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8384097 — Surrogate Endpoint (SUR): Serum potassium
Study 22700860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11464446 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7735153 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 29410606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11052431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11052431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29611171 — Surrogate Endpoint (SUR): Blood pressure
Study 29611171 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10624069 — Surrogate Endpoint (SUR): Blood pressure
Study 28032435 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 22484664 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 17659837 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 14764790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14764790 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14764790 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 14764790 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9105648 — Surrogate Endpoint (SUR): Blood pressure
Study 9105648 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31259628 — Surrogate Endpoint (SUR): Blood pressure
Study 23719216 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23719216 — Surrogate Endpoint (SUR): Blood pressure
Study 29789969 — Predictive Biomarker (PRD): Hormone receptor
Study 21028997 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21028997 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21028997 — Surrogate Endpoint (SUR): Blood pressure
Study 22200382 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22200382 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 15653117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15653117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10554570 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 10580169 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28545277 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18493215 — Surrogate Endpoint (SUR): Bacterial count
Study 2874032 — Surrogate Endpoint (SUR): Blood pressure
Study 31411963 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 23796235 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8904876 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 28993335 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23681159 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 21440749 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 27749321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27749321 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26407654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26407654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26407654 — Surrogate Endpoint (SUR): Blood pressure
Study 26407654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23943839 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 22288485 — Surrogate Endpoint (SUR): Probing pocket depth
Study 12463106 — Surrogate Endpoint (SUR): Blood pressure
Study 20708393 — Surrogate Endpoint (SUR): Blood pressure
Study 29951886 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29951886 — Surrogate Endpoint (SUR): Blood pressure
Study 26246443 — Safety Biomarker (SAF): DRD3
Study 16554448 — Predictive Biomarker (PRD): HNMT mRNA
Genes: HNMT
Study 1588379 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3838405 — Surrogate Endpoint (SUR): Blood pressure
Study 29072800 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20205704 — Surrogate Endpoint (SUR): Blood pressure
Study 8724043 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30746581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15256675 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15256675 — Surrogate Endpoint (SUR): Blood pressure
Study 3036903 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 3036903 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 26325644 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26325644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26325644 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 16504528 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 7912442 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31719527 — Surrogate Endpoint (SUR): Blood pressure
Study 19934816 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16467663 — Surrogate Endpoint (SUR): Blood pressure
Study 9292585 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8308770 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8308770 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20399986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20399986 — Surrogate Endpoint (SUR): Blood pressure
Study 6406586 — Surrogate Endpoint (SUR): Blood pressure
Study 18048467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11792411 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 27614854 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8840343 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30424786 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27548026 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 27548026 — Predictive Biomarker (PRD): HPGD mRNA
Genes: HPGD; PGDH1; SDR36C1
Study 27548026 — Predictive Biomarker (PRD): PTGER4 mRNA
Genes: PTGER4; PTGER2
Study 25448495 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25448495 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25448495 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 19844694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15878930 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20585296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2856779 — Surrogate Endpoint (SUR): Blood pressure
Study 21076842 — Surrogate Endpoint (SUR): Blood pressure
Study 25468411 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 17038636 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 17038636 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 17645253 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 7595984 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2220621 — Surrogate Endpoint (SUR): Blood pressure
Study 2220621 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8605634 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27376373 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 27376373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7806733 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 7154618 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7154618 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30659924 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24002343 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24002343 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 9686324 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8004363 — Surrogate Endpoint (SUR): Blood pressure
Study 11029598 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11029598 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11029598 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11029598 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27632067 — Safety Biomarker (SAF): Hyaluronic acid
Study 26193719 — Surrogate Endpoint (SUR): Bone mineral density
Study 24192120 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 24192120 — Predictive Biomarker (PRD): TANC2 mRNA
Genes: TANC2; KIAA1148; KIAA1636
Study 24192120 — Predictive Biomarker (PRD): APCDD1 mRNA
Genes: APCDD1; DRAPC1; FP7019
Study 24192120 — Predictive Biomarker (PRD): ABCC9 mRNA
Genes: ABCC9; SUR2
Study 24192120 — Predictive Biomarker (PRD): YIPF1 mRNA
Genes: YIPF1
Study 14636907 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8757204 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28169916 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28169916 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18080748 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18080748 — Surrogate Endpoint (SUR): Pathological complete response
Study 26964730 — Safety Biomarker (SAF): miR-22
Genes: MIR22
Study 21742443 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2508167 — Surrogate Endpoint (SUR): Blood pressure
Study 184309 — Surrogate Endpoint (SUR): Blood pressure
Study 31526964 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25393158 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23579523 — Surrogate Endpoint (SUR): Blood pressure
Study 18308881 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 16669961 — Safety Biomarker (SAF): Human leucocyte antigen
Study 10772526 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9193361 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9986921 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 25135724 — Monitoring Biomarker (MOI): HBV DNA
Study 12709272 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22390816 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14766772 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 14766772 — Safety Biomarker (SAF): Reactive oxygen species
Study 9741610 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20551163 — Predictive Biomarker (PRD): HNMT mRNA
Genes: HNMT
Study 20551163 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 20551163 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20551163 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 20551163 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 10225667 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 2009148 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26602423 — Predictive Biomarker (PRD): IGFBP2 mRNA
Genes: IGFBP2; BP2; IBP2
Study 26602423 — Surrogate Endpoint (SUR): Serum calcium
Study 8210018 — Surrogate Endpoint (SUR): Blood pressure
Study 31657838 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 27760062 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 7926297 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 7926297 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 31242931 — Surrogate Endpoint (SUR): Blood pressure
Study 28396516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28396516 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 28396516 — Predictive Biomarker (PRD): COL3A1 mRNA
Genes: COL3A1
Study 21193187 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 21193187 — Surrogate Endpoint (SUR): Bone mineral density
Study 8516520 — Surrogate Endpoint (SUR): Blood pressure
Study 2434789 — Surrogate Endpoint (SUR): Blood pressure
Study 30721390 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 29800034 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24166586 — Monitoring Biomarker (MOI): HBV DNA
Study 8315261 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 20814967 — Surrogate Endpoint (SUR): Bone mineral density
Study 12965266 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 12965266 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 29357859 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 22340631 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22340631 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28628560 — Predictive Biomarker (PRD): HCAR2 mRNA
Genes: HCAR2; GPR109A; HCA2; HM74A; NIACR1
Study 28628560 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28628560 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24156189 — Surrogate Endpoint (SUR): Blood pressure
Study 17494926 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11562625 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 29180023 — Surrogate Endpoint (SUR): Serum potassium
Study 23822942 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 19393139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12873431 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 10539230 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1855327 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 6681030 — Surrogate Endpoint (SUR): Blood pressure
Study 27917802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 27302432 — Surrogate Endpoint (SUR): Blood pressure
Study 16002160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16002160 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 12796127 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3000138 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25338425 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19692216 — Surrogate Endpoint (SUR): Blood pressure
Study 11312474 — Surrogate Endpoint (SUR): Blood pressure
Study 31848169 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 19383515 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 17341866 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21054224 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 10211050 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23650412 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 23650412 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23650412 — Predictive Biomarker (PRD): Hormone receptor
Study 11789776 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9670287 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31456449 — Surrogate Endpoint (SUR): Blood pressure
Study 26630617 — Safety Biomarker (SAF): Hyaluronic acid
Study 21977856 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21977856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21977856 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21977856 — Safety Biomarker (SAF): IL-6 and IL-10
Study 31919558 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 28590957 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 28590957 — Predictive Biomarker (PRD): TPH2 mRNA
Genes: TPH2; NTPH
Study 28590957 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 22308697 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22308697 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22308697 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11696046 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 3067303 — Surrogate Endpoint (SUR): Blood pressure
Study 28587582 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28587582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25331850 — Surrogate Endpoint (SUR): Blood pressure
Study 23218699 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21774626 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 11742432 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11774933 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 9269706 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9269706 — Surrogate Endpoint (SUR): Serum creatinine
Study 8003922 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 30028241 — Surrogate Endpoint (SUR): Blood pressure
Study 18852661 — Surrogate Endpoint (SUR): Serum creatinine
Study 12352275 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6367245 — Surrogate Endpoint (SUR): Blood pressure
Study 9508171 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 9508171 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1