TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00744211 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT00744211 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT04409899 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01652482 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02771314 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02771314 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02771314 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT02131675 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study NCT04494139 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01759056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02530801 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02530801 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02448251 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02448251 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02361944 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00350168 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01701999 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00445653 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00445653 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study NCT01050413 — Predictive Biomarker (PRD): TK1 mRNA
Genes: TK1
Study NCT03479814 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00975169 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT00975169 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study NCT00975169 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study NCT01836094 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT03863171 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT03401242 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study NCT04448067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01083524 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT00175877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00226447 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02130648 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04269031 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study NCT00447265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03741101 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00348920 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT00348920 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02730052 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01937598 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01700270 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01713270 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00056537 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study NCT03470038 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02991651 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01925352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT01637909 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02019823 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04297501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01852240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01852240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01852240 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study NCT01852240 — Safety Biomarker (SAF): Interleukin 1
Study NCT01806857 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00789880 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study NCT02717884 — Predictive Biomarker (PRD): KDM1A mRNA
Genes: KDM1A; AOF2; KDM1; KIAA0601; LSD1
Study NCT04960540 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02957591 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02957591 — Safety Biomarker (SAF): Interleukin 1
Study NCT02957591 — Safety Biomarker (SAF): BDNF
Study NCT02099864 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02099864 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01591967 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02704338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02704338 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study NCT03439384 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04071327 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02009982 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03590028 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03239340 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03239340 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01033656 — Safety Biomarker (SAF): Interleukin 1
Study NCT03420079 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04667910 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02000596 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06599346 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT05219032 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03397966 — Predictive Biomarker (PRD): UCP1 mRNA
Genes: UCP1; SLC25A7; UCP
Study NCT03397966 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00827684 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03140332 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT00298129 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00589498 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00623974 — Surrogate Endpoint (SUR): Serum calcium
Study NCT00404066 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT06256133 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT06256133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02678338 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study NCT00657865 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01017367 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study NCT04351711 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04351711 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study NCT04351711 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04351711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04351711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04351711 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04351711 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT04351711 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04351711 — Safety Biomarker (SAF): Interleukin 1
Study NCT04351711 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT04351711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04351711 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT04351711 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT04351711 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT04351711 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT04351711 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study NCT03541785 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03833934 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03992456 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03905330 — Predictive Biomarker (PRD): ATP8B1 mRNA
Genes: ATP8B1; ATPIC; FIC1; PFIC
Study NCT04162301 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT02126449 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02433743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00095706 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00095706 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00095706 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03373981 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00270985 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00473551 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02080468 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02386995 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04054557 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04054557 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01193829 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02388659 — Pharmacodynamic Biomarker (PDY): 2-hydroxyglutarate
Study NCT04905238 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT01535339 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT02149277 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT02149277 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00046410 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01345721 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study NCT03808389 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT03135171 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00003757 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study NCT00334386 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04349163 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00094900 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study NCT00094900 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT00094900 — Safety Biomarker (SAF): Interleukin 1
Study NCT03093571 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00277251 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00990054 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT00990054 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03229408 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04384393 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02724215 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01817283 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01436942 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00960232 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00865904 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00865904 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study NCT02650336 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03060343 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT03060343 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study NCT03026933 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT05056740 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT04860037 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study NCT00272883 — Predictive Biomarker (PRD): SELENON mRNA
Genes: SELENON; SELN; SEPN1
Study NCT00272883 — Predictive Biomarker (PRD): RYR1 mRNA
Genes: RYR1; RYDR
Study NCT01929239 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01929239 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04353479 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02998645 — Surrogate Endpoint (SUR): Hematologic response
Study NCT02408107 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02408107 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03882203 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01621542 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT04838665 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01378104 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT02271724 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT02271724 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04045704 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02748850 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02748850 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT02896829 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02896829 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04216134 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00514774 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00759733 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03911973 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02145533 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04489251 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study NCT04489251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01550120 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01248286 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT04558567 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03716180 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03864783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03864783 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04040764 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01824238 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02000076 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study NCT00197197 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT00256217 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00256217 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00256217 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00001181 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03311321 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT02525393 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT00830245 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01692561 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02596243 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03738878 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02223156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02223156 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03569046 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06703086 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT06703086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01667536 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT00653042 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04314531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02910271 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00079859 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04484636 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Tumor mutational burden
Study NCT04484636 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT05830981 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT04582903 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01451008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04756310 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04756310 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03293615 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02968134 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03686124 — Predictive Biomarker (PRD): PRAME mRNA
Genes: PRAME; MAPE; OIP4
Study NCT02674568 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study NCT02928562 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04285736 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04285736 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02545621 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT02545621 — Predictive Biomarker (PRD): TXNIP mRNA
Genes: TXNIP; VDUP1
Study NCT02545621 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study NCT02545621 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT02263677 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03858842 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03747315 — Predictive Biomarker (PRD): MEFV mRNA
Genes: MEFV; MEF; TRIM20
Study NCT03479697 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02642003 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT04438486 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04137068 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04403646 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03853473 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00062517 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02144480 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study NCT04097470 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01650142 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01205074 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT00791258 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02840357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04062019 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02677948 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT02677948 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01368536 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03558165 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03558165 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02116504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00655954 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT01032096 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01032096 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01032096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT02594423 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02594423 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02147366 — Surrogate Endpoint (SUR): Blood pressure