TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1836088 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1836088 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1836088 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27276431 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 27276431 — Predictive Biomarker (PRD): FADS2 mRNA
Genes: FADS2
Study 23765601 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30650256 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 20628884 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 15822121 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15513305 — Surrogate Endpoint (SUR): Blood pressure
Study 11757505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23563752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15966878 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10073741 — Surrogate Endpoint (SUR): Blood pressure
Study 6387888 — Surrogate Endpoint (SUR): Blood pressure
Study 26785820 — Surrogate Endpoint (SUR): Blood pressure
Study 11846197 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 11846197 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 2311595 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27502725 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8214926 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25503265 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23841295 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8607888 — Surrogate Endpoint (SUR): Bone mineral density
Study 29415145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23957715 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 7493428 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3876579 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 21941790 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17148971 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8440540 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 10503809 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10503809 — Surrogate Endpoint (SUR): Serum creatinine
Study 10503809 — Surrogate Endpoint (SUR): Blood pressure
Study 1777372 — Surrogate Endpoint (SUR): Blood pressure
Study 21295433 — Surrogate Endpoint (SUR): Blood pressure
Study 19299239 — Predictive Biomarker (PRD): Hormone receptor
Study 11600560 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9844752 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 20212518 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 16414143 — Surrogate Endpoint (SUR): Blood pressure
Study 8866086 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 8866086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8866086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31318460 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19968580 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19968580 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23633679 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15310394 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 9717064 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22990217 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 20102633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14575726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14575726 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 14575726 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14575726 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24329856 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 18277828 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9917116 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30936043 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 26335078 — Surrogate Endpoint (SUR): Blood pressure
Study 10871912 — Surrogate Endpoint (SUR): Bone mineral density
Study 10871912 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9003876 — Surrogate Endpoint (SUR): Blood pressure
Study 22795636 — Surrogate Endpoint (SUR): Blood pressure
Study 19744537 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 17162326 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11355929 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28538556 — Safety Biomarker (SAF): Hyaluronic acid
Study 24231251 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 24231251 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 21989182 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 9008249 — Surrogate Endpoint (SUR): Blood pressure
Study 8495604 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27650514 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20560909 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 20560909 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20560909 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 7437258 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 22305837 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 31849040 — Safety Biomarker (SAF): Reactive oxygen species
Study 1725029 — Surrogate Endpoint (SUR): Blood pressure
Study 19225296 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19225296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12090907 — Surrogate Endpoint (SUR): Blood pressure
Study 959765 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 21504407 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17526179 — Predictive Biomarker (PRD): PLIN2 mRNA
Genes: PLIN2; ADFP
Study 9663911 — Surrogate Endpoint (SUR): Blood pressure
Study 28169258 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 28169258 — Surrogate Endpoint (SUR): Probing pocket depth
Study 20533219 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9813559 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 828982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24458801 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24458801 — Safety Biomarker (SAF): Urinary total protein
Study 21330640 — Surrogate Endpoint (SUR): Blood pressure
Study 14699004 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14699004 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8950781 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8950781 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1850722 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 6890374 — Surrogate Endpoint (SUR): Blood pressure
Study 24923998 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23212275 — Surrogate Endpoint (SUR): Serum creatinine
Study 12490682 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 203998 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27253202 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 22500381 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 8642806 — Surrogate Endpoint (SUR): Blood pressure
Study 30946197 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23704196 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12575590 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12575590 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24067537 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16790616 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16790616 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16790616 — Surrogate Endpoint (SUR): Blood pressure
Study 30341453 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28484308 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28484308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28484308 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 28484308 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28484308 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 23874021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23874021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23874021 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 23874021 — Safety Biomarker (SAF): Interleukin 1
Study 23874021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8070990 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 3330116 — Surrogate Endpoint (SUR): Blood pressure
Study 23931044 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 16980158 — Surrogate Endpoint (SUR): Serum creatinine
Study 10687148 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2872054 — Surrogate Endpoint (SUR): Blood pressure
Study 25168488 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19674789 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10583450 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30061073 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23478695 — Surrogate Endpoint (SUR): Blood pressure
Study 19289630 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11230836 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25155998 — Surrogate Endpoint (SUR): Blood pressure
Study 11491415 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29607323 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 31296884 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 19638025 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 7865997 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30093401 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 28476923 — Surrogate Endpoint (SUR): Blood pressure
Study 30486262 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 376211 — Surrogate Endpoint (SUR): Blood pressure
Study 25983123 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 29241762 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26840330 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 20854662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20854662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19016147 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 19016147 — Surrogate Endpoint (SUR): Serum creatinine
Study 19016147 — Surrogate Endpoint (SUR): Blood pressure
Study 10781640 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29846031 — Surrogate Endpoint (SUR): Blood pressure
Study 29846031 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18687376 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 18687376 — Safety Biomarker (SAF): DRD2
Study 16162624 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16162624 — Surrogate Endpoint (SUR): Blood pressure
Study 7759412 — Surrogate Endpoint (SUR): Blood pressure
Study 23431120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23431120 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23431120 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 20587725 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20587725 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 20587725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20587725 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29952408 — Surrogate Endpoint (SUR): Blood pressure
Study 26473667 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 24446153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24446153 — Surrogate Endpoint (SUR): Blood pressure
Study 20374607 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16926382 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11251917 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 10434166 — Surrogate Endpoint (SUR): Blood pressure
Study 20061926 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10620211 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8880055 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 8880055 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8880055 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30459575 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30459575 — Safety Biomarker (SAF): BDNF
Study 24556829 — Surrogate Endpoint (SUR): Blood pressure
Study 24556829 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21931125 — Surrogate Endpoint (SUR): Blood pressure
Study 31243480 — Surrogate Endpoint (SUR): Bone mineral density
Study 24622716 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23011525 — Surrogate Endpoint (SUR): Blood pressure
Study 8013758 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24379055 — Safety Biomarker (SAF): Hyaluronic acid
Study 3065411 — Surrogate Endpoint (SUR): Blood pressure
Study 23864141 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 21600570 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 15190232 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 22388610 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 22388610 — Surrogate Endpoint (SUR): Serum potassium
Study 22388610 — Surrogate Endpoint (SUR): Serum calcium
Study 10499652 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30286625 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 25066269 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20845988 — Monitoring Biomarker (MOI): Cell-free DNA
Study 15638875 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 15638875 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15638875 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15638875 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26696093 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20501982 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 23774275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11304971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11304971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8640980 — Surrogate Endpoint (SUR): Blood pressure
Study 6596056 — Surrogate Endpoint (SUR): Blood pressure
Study 26038818 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 26038818 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26038818 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24577230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24577230 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22118780 — Surrogate Endpoint (SUR): Blood pressure
Study 17952847 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7786951 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21757938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21757938 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21757938 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19371315 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12571674 — Surrogate Endpoint (SUR): Serum calcium
Study 9181277 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9181277 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1327049 — Surrogate Endpoint (SUR): Blood pressure
Study 28920550 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 28920550 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 20562069 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 30680852 — Surrogate Endpoint (SUR): Blood pressure
Study 26360979 — Surrogate Endpoint (SUR): Blood pressure
Study 24151272 — Surrogate Endpoint (SUR): Bone mineral density
Study 21377153 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 21377153 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19688314 — Surrogate Endpoint (SUR): Blood pressure
Study 7797904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7011531 — Predictive Biomarker (PRD): POMP mRNA
Genes: POMP; C13orf12; UMP1; HSPC014; HSPC036; PNAS-110
Study 7011531 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 29914146 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21895621 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18806050 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18806050 — Surrogate Endpoint (SUR): Blood pressure
Study 25765348 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 15581196 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31584780 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 24169346 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15477795 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11229849 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27329124 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 12629246 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 7930384 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 2975291 — Surrogate Endpoint (SUR): Blood pressure
Study 20979574 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 11147929 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8629631 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8629631 — Surrogate Endpoint (SUR): Serum uric acid
Study 8629631 — Surrogate Endpoint (SUR): Blood pressure
Study 31403812 — Surrogate Endpoint (SUR): Blood pressure
Study 26891150 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19653067 — Surrogate Endpoint (SUR): Blood pressure
Study 231324 — Surrogate Endpoint (SUR): Blood pressure
Study 16769944 — Predictive Biomarker (PRD): KCNJ2 mRNA
Genes: KCNJ2; IRK1
Study 9251276 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 3493333 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 22035675 — Surrogate Endpoint (SUR): Blood pressure
Study 29079252 — Surrogate Endpoint (SUR): Blood pressure
Study 19028124 — Surrogate Endpoint (SUR): Bone mineral density
Study 11699049 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11699049 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31148332 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 31148332 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28587581 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25246074 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25246074 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25246074 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 25246074 — Safety Biomarker (SAF): Hyaluronic acid
Study 28610818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28610818 — Safety Biomarker (SAF): Interleukin 1