TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18260939 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18260939 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16231621 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16231621 — Surrogate Endpoint (SUR): Blood pressure
Study 12116339 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9987705 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 2187981 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 18756880 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 8786174 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30972712 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 24293332 — Surrogate Endpoint (SUR): Blood pressure
Study 16301237 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9816887 — Predictive Biomarker (PRD): RAPH1 mRNA
Genes: RAPH1; ALS2CR18; ALS2CR9; KIAA1681; LPD; PREL2; RMO1
Study 31043161 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31043161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31043161 — Surrogate Endpoint (SUR): Blood pressure
Study 27384376 — Surrogate Endpoint (SUR): Blood pressure
Study 23981814 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23981814 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21254162 — Surrogate Endpoint (SUR): Serum creatinine
Study 21254162 — Monitoring Biomarker (MOI): HBV DNA
Study 12040766 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9701417 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7838917 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 21494635 — Surrogate Endpoint (SUR): Blood pressure
Study 3033180 — Surrogate Endpoint (SUR): Blood pressure
Study 29923305 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12104065 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12104065 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10588465 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1673616 — Surrogate Endpoint (SUR): Blood pressure
Study 29260292 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22090672 — Surrogate Endpoint (SUR): Blood pressure
Study 18477130 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18477130 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7631329 — Surrogate Endpoint (SUR): Blood pressure
Study 7631329 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29596010 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 28049139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28049139 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28049139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 28049139 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20689466 — Surrogate Endpoint (SUR): Bone mineral density
Study 9519749 — Surrogate Endpoint (SUR): Blood pressure
Study 9519749 — Surrogate Endpoint (SUR): Serum creatinine
Study 1893304 — Surrogate Endpoint (SUR): Blood pressure
Study 25645091 — Surrogate Endpoint (SUR): Serum creatinine
Study 25645091 — Surrogate Endpoint (SUR): Serum calcium
Study 25645091 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 23539907 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20931329 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20931329 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16980161 — Surrogate Endpoint (SUR): Blood pressure
Study 10774967 — Surrogate Endpoint (SUR): Blood pressure
Study 29316164 — Surrogate Endpoint (SUR): Blood pressure
Study 25622626 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 25622626 — Surrogate Endpoint (SUR): Serum creatinine
Study 23310938 — Surrogate Endpoint (SUR): Blood pressure
Study 8801446 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1430701 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 30720538 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30720538 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 30720538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30720538 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 30720538 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30720538 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 2161692 — Surrogate Endpoint (SUR): Serum calcium
Study 2161692 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23889806 — Safety Biomarker (SAF): 51Cr-EDTA
Study 21827773 — Safety Biomarker (SAF): Reactive oxygen species
Study 21827773 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9715310 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 25719441 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 25719441 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25719441 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24615500 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24615500 — Predictive Biomarker (PRD): Hormone receptor
Study 19670432 — Surrogate Endpoint (SUR): Blood pressure
Study 9935128 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 27761984 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study 24512486 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 24512486 — Predictive Biomarker (PRD): SSTR1 mRNA
Genes: SSTR1
Study 19346521 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15531660 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 11809123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24812287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23324897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23324897 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23324897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17152732 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17152732 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 17152732 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14747052 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10694774 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15714177 — Surrogate Endpoint (SUR): Bone mineral density
Study 15714177 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 12890859 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 11050579 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 31746742 — Surrogate Endpoint (SUR): Blood pressure
Study 24759125 — Surrogate Endpoint (SUR): Blood pressure
Study 21805307 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20080837 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20080837 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8417049 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12631089 — Surrogate Endpoint (SUR): Urinary oxalate
Study 28193231 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 28193231 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19489488 — Surrogate Endpoint (SUR): Blood pressure
Study 31880795 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 25050986 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 17559628 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 25403334 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25403334 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 25403334 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 25403334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21241369 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 10704621 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 8403580 — Safety Biomarker (SAF): Hyaluronic acid
Study 18398095 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16872244 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14635608 — Surrogate Endpoint (SUR): Blood pressure
Study 1731577 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 9656236 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12138261 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29615318 — Surrogate Endpoint (SUR): Serum calcium
Study 19786670 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19786670 — Predictive Biomarker (PRD): Hormone receptor
Study 16338019 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 8434556 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22397815 — Predictive Biomarker (PRD): KLK4 mRNA
Genes: KLK4; EMSP1; PRSS17; PSTS
Study 22397815 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 22397815 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27605038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27605038 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8148353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23704675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23704675 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22527287 — Safety Biomarker (SAF): RYR1
Genes: RYR; PPP1R137
Study 22527287 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22527287 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22527287 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10385662 — Monitoring Biomarker (MOI): HBV DNA
Study 6441537 — Surrogate Endpoint (SUR): Blood pressure
Study 14727947 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14727947 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10540365 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10540365 — Surrogate Endpoint (SUR): Serum calcium
Study 21131631 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 19583605 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19583605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28673363 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 28673363 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11472042 — Surrogate Endpoint (SUR): Blood pressure
Study 8049831 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 25500202 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 23363981 — Surrogate Endpoint (SUR): Serum creatinine
Study 14510756 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8409106 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29898752 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28115966 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 28115966 — Surrogate Endpoint (SUR): Blood pressure
Study 17935553 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17935553 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17935553 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15736119 — Surrogate Endpoint (SUR): Blood pressure
Study 12137603 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12137603 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2550045 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2550045 — Surrogate Endpoint (SUR): Blood pressure
Study 31052322 — Surrogate Endpoint (SUR): Blood pressure
Study 24636286 — Monitoring Biomarker (MOI): HBV DNA
Study 9064671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6145533 — Surrogate Endpoint (SUR): Blood pressure
Study 29957706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25375154 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 11115439 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9175684 — Safety Biomarker (SAF): Interleukin 1
Study 9175684 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29229342 — Predictive Biomarker (PRD): SLC25A3 mRNA
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 1328817 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30081930 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 17709169 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15986592 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10703890 — Surrogate Endpoint (SUR): Blood pressure
Study 30228368 — Surrogate Endpoint (SUR): Blood pressure
Study 21697538 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10720025 — Surrogate Endpoint (SUR): Bone mineral density
Study 3999921 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 30014331 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 12660531 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23238616 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 30269143 — Surrogate Endpoint (SUR): Blood pressure
Study 24508204 — Predictive Biomarker (PRD): PPP1R13L mRNA
Genes: PPP1R13L; IASPP; NKIP1; PPP1R13BL; RAI
Study 19996069 — Surrogate Endpoint (SUR): Blood pressure
Study 15987849 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 25491299 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20595285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20595285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7641363 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2238185 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2238185 — Surrogate Endpoint (SUR): Blood pressure
Study 31215156 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 31215156 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 26277033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26277033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7916274 — Surrogate Endpoint (SUR): Blood pressure
Study 20625342 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 18025525 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 18025525 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 18025525 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12166339 — Surrogate Endpoint (SUR): Serum calcium
Study 18645322 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 21163558 — Surrogate Endpoint (SUR): Blood pressure
Study 19570039 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12170362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7749832 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2301259 — Surrogate Endpoint (SUR): Blood pressure
Study 31918243 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21936966 — Predictive Biomarker (PRD): GPX3 mRNA
Genes: GPX3; GPXP
Study 21936966 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 11464715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9972055 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 29148175 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 9012686 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 9012686 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 31692559 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CSPG4 mRNA
Genes: CSPG4; MCSP
Study 29269513 — Predictive Biomarker (PRD): F2RL3 mRNA
Genes: F2RL3; PAR4
Study 19406976 — Safety Biomarker (SAF): Reactive oxygen species
Study 17446813 — Surrogate Endpoint (SUR): Serum creatinine
Study 23078531 — Surrogate Endpoint (SUR): Blood pressure
Study 23078531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18555517 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17031403 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17031403 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 17031403 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 17031403 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 17031403 — Predictive Biomarker (PRD): CD6 mRNA
Genes: CD6
Study 17031403 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 17031403 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 17031403 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 17031403 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7710841 — Predictive Biomarker (PRD): Liver iron
Study 3236318 — Surrogate Endpoint (SUR): Blood pressure
Study 25526733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 14535967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 10933361 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10933361 — Surrogate Endpoint (SUR): Blood pressure
Study 8299252 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3883917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29397160 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24270743 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 24270743 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16351668 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16351668 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1940682 — Surrogate Endpoint (SUR): Blood pressure
Study 22951349 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22951349 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22951349 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19317065 — Surrogate Endpoint (SUR): Serum calcium
Study 17410461 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 9849273 — Surrogate Endpoint (SUR): Blood pressure
Study 8014393 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25940759 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 11256874 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11256874 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 19924010 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1826071 — Surrogate Endpoint (SUR): Blood pressure
Study 30938760 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15333608 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 18678703 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31779786 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18228523 — Predictive Biomarker (PRD): MITF mRNA
Genes: MITF; BHLHE32
Study 16472797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16472797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1835914 — Surrogate Endpoint (SUR): Blood pressure
Study 1835914 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25330083 — Surrogate Endpoint (SUR): Blood pressure
Study 27918931 — Surrogate Endpoint (SUR): Blood pressure
Study 27918931 — Surrogate Endpoint (SUR): Serum potassium
Study 11213545 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 11213545 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3546779 — Surrogate Endpoint (SUR): Blood pressure
Study 29484548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29484548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27390150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27390150 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17941871 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17941871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1