TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22989086 — Surrogate Endpoint (SUR): Blood pressure
Study 22989086 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19028052 — Surrogate Endpoint (SUR): Serum creatinine
Study 9626838 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 26857949 — Surrogate Endpoint (SUR): Serum potassium
Study 25659589 — Surrogate Endpoint (SUR): Blood pressure
Study 21223712 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 18371487 — Surrogate Endpoint (SUR): Serum creatinine
Study 18371487 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31871045 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 6345374 — Surrogate Endpoint (SUR): Blood pressure
Study 29336388 — Surrogate Endpoint (SUR): Blood pressure
Study 27574437 — Surrogate Endpoint (SUR): Blood pressure
Study 27574437 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27574437 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 848704 — Surrogate Endpoint (SUR): Serum sodium
Study 19330241 — Surrogate Endpoint (SUR): Blood pressure
Study 26509984 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 23028039 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19493408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19493408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19493408 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 19493408 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 1979092 — Surrogate Endpoint (SUR): Blood pressure
Study 25022125 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25022125 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20878849 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 11442535 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9879412 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7986713 — Surrogate Endpoint (SUR): Serum calcium
Study 11327191 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 7514874 — Surrogate Endpoint (SUR): Total kidney volume
Study 7514874 — Surrogate Endpoint (SUR): Blood pressure
Study 29769203 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27124177 — Predictive Biomarker (PRD): Hormone receptor
Study 25703119 — Surrogate Endpoint (SUR): Serum creatinine
Study 10494457 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 1848169 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 31675538 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 31675538 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 29604599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29604599 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19721013 — Predictive Biomarker (PRD): Liver iron
Study 17352516 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11157138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9626844 — Surrogate Endpoint (SUR): Blood pressure
Study 23899829 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23899829 — Surrogate Endpoint (SUR): Blood pressure
Study 19651674 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 21723781 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 14747423 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14747423 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11392657 — Predictive Biomarker (PRD): SOAT1 mRNA
Genes: SOAT1; ACACT; ACACT1; ACAT; ACAT1; SOAT; STAT
Study 10367611 — Surrogate Endpoint (SUR): Blood pressure
Study 8889266 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25349333 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23786930 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21784046 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 13679494 — Surrogate Endpoint (SUR): Serum uric acid
Study 13679494 — Surrogate Endpoint (SUR): Blood pressure
Study 20137091 — Surrogate Endpoint (SUR): Blood pressure
Study 17432674 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 17432674 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 17432674 — Safety Biomarker (SAF): BDNF
Study 17432674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7742723 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31870424 — Surrogate Endpoint (SUR): Blood pressure
Study 3312933 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31189655 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27609846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27609846 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 18400709 — Surrogate Endpoint (SUR): Blood pressure
Study 1748037 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7258126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31173468 — Monitoring Biomarker (MOI): HBV DNA
Study 22264599 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 22264599 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 17211096 — Surrogate Endpoint (SUR): Bone mineral density
Study 17211096 — Surrogate Endpoint (SUR): Serum calcium
Study 9784078 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 28985328 — Surrogate Endpoint (SUR): Blood pressure
Study 25352300 — Monitoring Biomarker (MOI): HBV DNA
Study 23314393 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 17186003 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17186003 — Surrogate Endpoint (SUR): Blood pressure
Study 11928585 — Surrogate Endpoint (SUR): Blood pressure
Study 12669132 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 12669132 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 10550467 — Surrogate Endpoint (SUR): Bone mineral density
Study 27367723 — Surrogate Endpoint (SUR): Blood pressure
Study 23484910 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 23484910 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 17512232 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17512232 — Surrogate Endpoint (SUR): Serum sodium
Study 26655163 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26655163 — Surrogate Endpoint (SUR): Blood pressure
Study 20130660 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11193281 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9033197 — Surrogate Endpoint (SUR): Blood pressure
Study 1670744 — Surrogate Endpoint (SUR): Blood pressure
Study 6138086 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30944048 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28355198 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 16586188 — Surrogate Endpoint (SUR): Bone mineral density
Study 28185708 — Predictive Biomarker (PRD): RUNX2 mRNA
Genes: RUNX2; AML3; CBFA1; OSF2; PEBP2A
Study 28185708 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28185708 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23712068 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 18196202 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24792735 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21707914 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17693145 — Predictive Biomarker (PRD): SLC22A5 mRNA
Genes: SLC22A5; OCTN2
Study 14684587 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15762 — Surrogate Endpoint (SUR): Blood pressure
Study 21971743 — Surrogate Endpoint (SUR): Blood pressure
Study 19463339 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1277749 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31423869 — Surrogate Endpoint (SUR): Blood pressure
Study 15223402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15223402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15223402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31536766 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 22152079 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9583482 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7657029 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28677982 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28677982 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24617605 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 24617605 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 17470740 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17470740 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17470740 — Predictive Biomarker (PRD): Hormone receptor
Study 15697102 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24218517 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 24218517 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 21753226 — Surrogate Endpoint (SUR): Blood pressure
Study 19164401 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 17086095 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 26303694 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26303694 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21451458 — Surrogate Endpoint (SUR): Blood pressure
Study 19483355 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9517371 — Surrogate Endpoint (SUR): Blood pressure
Study 7527104 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7527104 — Surrogate Endpoint (SUR): Blood pressure
Study 27936084 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25607702 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 3745103 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3745103 — Surrogate Endpoint (SUR): Blood pressure
Study 26679060 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 24879495 — Surrogate Endpoint (SUR): Blood pressure
Study 15994038 — Surrogate Endpoint (SUR): Serum testosterone
Study 12585143 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 6788282 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30188800 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30188800 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15803263 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study 9643568 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 9643568 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9643568 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 3063328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 24885377 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 20359612 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 2662100 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 23840043 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23840043 — Safety Biomarker (SAF): Interleukin 12
Study 23532240 — Surrogate Endpoint (SUR): Serum creatinine
Study 18761646 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 10457270 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 10457270 — Surrogate Endpoint (SUR): Bone mineral density
Study 30593689 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27220840 — Surrogate Endpoint (SUR): Blood pressure
Study 27220840 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15767219 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31535143 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31535143 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25003812 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 25003812 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study 2260146 — Surrogate Endpoint (SUR): Blood pressure
Study 6779673 — Surrogate Endpoint (SUR): Blood pressure
Study 28217871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28217871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21212059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19186961 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 2529108 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 1068646 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 14734517 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 28722766 — Surrogate Endpoint (SUR): Bone mineral density
Study 27457257 — Surrogate Endpoint (SUR): Blood pressure
Study 16841676 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11036121 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11036121 — Surrogate Endpoint (SUR): Serum creatinine
Study 8858271 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8858271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20535920 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30627845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30627845 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study 27811204 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27811204 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27811204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23689036 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 23689036 — Predictive Biomarker (PRD): SLC2A5 mRNA
Genes: SLC2A5; GLUT5
Study 17356110 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 2892458 — Surrogate Endpoint (SUR): Blood pressure
Study 27294814 — Surrogate Endpoint (SUR): Blood pressure
Study 24552320 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24552320 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23750033 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23750033 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30249121 — Surrogate Endpoint (SUR): Blood pressure
Study 27160246 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27160246 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18158849 — Surrogate Endpoint (SUR): Serum uric acid
Study 16316352 — Surrogate Endpoint (SUR): Blood pressure
Study 7962441 — Surrogate Endpoint (SUR): Sperm parameters
Study 3688927 — Surrogate Endpoint (SUR): Blood pressure
Study 27576169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24786217 — Surrogate Endpoint (SUR): Blood pressure
Study 24786217 — Surrogate Endpoint (SUR): Serum creatinine
Study 16192247 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8626943 — Surrogate Endpoint (SUR): Blood pressure
Study 31505974 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 21830844 — Surrogate Endpoint (SUR): Blood pressure
Study 7657919 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31273244 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25689743 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22126115 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30768490 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 28774856 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 28774856 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 11740191 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9758086 — Surrogate Endpoint (SUR): Blood pressure
Study 29603591 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 12823389 — Surrogate Endpoint (SUR): Blood pressure
Study 9685441 — Surrogate Endpoint (SUR): Blood pressure
Study 10026839 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10026839 — Surrogate Endpoint (SUR): Blood pressure
Study 29077152 — Safety Biomarker (SAF): Hyaluronic acid
Study 21613972 — Surrogate Endpoint (SUR): Bone mineral density
Study 13678770 — Surrogate Endpoint (SUR): Bone mineral density
Study 29112963 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24270132 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11579891 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 15253956 — Surrogate Endpoint (SUR): Serum testosterone
Study 15253956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11849859 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11849859 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16728696 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6497518 — Surrogate Endpoint (SUR): Serum potassium
Study 21070297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21070297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21070297 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21070297 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14720615 — Surrogate Endpoint (SUR): Blood pressure
Study 9114758 — Surrogate Endpoint (SUR): Blood pressure
Study 8625548 — Predictive Biomarker (PRD): LGSN mRNA
Genes: LGSN; GLULD1; LGS
Study 1340743 — Surrogate Endpoint (SUR): Blood pressure
Study 30178515 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 27553581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24554512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24554512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15321222 — Surrogate Endpoint (SUR): Blood pressure
Study 7923256 — Surrogate Endpoint (SUR): Blood pressure
Study 3136963 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 26445075 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19293355 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19293355 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19293355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26517587 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 11312481 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7717370 — Predictive Biomarker (PRD): RARS1 mRNA
Genes: RARS1; RARS
Study 26482865 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 26482865 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 26482865 — Predictive Biomarker (PRD): TFAM mRNA
Genes: TFAM; TCF6; TCF6L2
Study 26482865 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 26482865 — Safety Biomarker (SAF): Reactive oxygen species
Study 22180452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22180452 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19566585 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 16253583 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16253583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17264952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17264952 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17264952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGB mRNA
Genes: FGB
Study 11583477 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26082611 — Surrogate Endpoint (SUR): Blood pressure
Study 19694343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30203153 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST