TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25795948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25795948 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19711135 — Surrogate Endpoint (SUR): Blood pressure
Study 30018370 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9589226 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2917924 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26082625 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 23365106 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23365106 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23365106 — Surrogate Endpoint (SUR): Blood pressure
Study 21274983 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 17053350 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29566095 — Safety Biomarker (SAF): IL-6 and IL-10
Study 26879069 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25915488 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25915488 — Surrogate Endpoint (SUR): Blood pressure
Study 16882185 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8678277 — Surrogate Endpoint (SUR): Blood pressure
Study 2932514 — Surrogate Endpoint (SUR): Blood pressure
Study 29807159 — Surrogate Endpoint (SUR): Blood pressure
Study 23918683 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 23918683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 23918683 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 23918683 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 10792094 — Surrogate Endpoint (SUR): Sperm parameters
Study 8704686 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23726175 — Surrogate Endpoint (SUR): Blood pressure
Study 11686543 — Surrogate Endpoint (SUR): Serum potassium
Study 22142767 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12738015 — Surrogate Endpoint (SUR): Blood pressure
Study 15917336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19043252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19043252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12747340 — Surrogate Endpoint (SUR): Blood pressure
Study 8580386 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2550642 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23277250 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 23277250 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16437269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16437269 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16437269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16437269 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8681595 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 6395323 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31074700 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 28545189 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19273701 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19273701 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11167370 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9129487 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3729666 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 22412041 — Surrogate Endpoint (SUR): Bone mineral density
Study 22412041 — Predictive Biomarker (PRD): Hormone receptor
Study 18072873 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16794892 — Surrogate Endpoint (SUR): Blood pressure
Study 12634875 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30379814 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 23514685 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 23514685 — Surrogate Endpoint (SUR): Blood pressure
Study 16248952 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16248952 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28968735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28968735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12713766 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7828254 — Surrogate Endpoint (SUR): Blood pressure
Study 23751021 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 19661244 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9595647 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7945475 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2835890 — Surrogate Endpoint (SUR): Blood pressure
Study 2835890 — Surrogate Endpoint (SUR): Serum potassium
Study 2835890 — Surrogate Endpoint (SUR): Serum creatinine
Study 28855173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28855173 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29019365 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 29019365 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29019365 — Safety Biomarker (SAF): Reactive oxygen species
Study 24365871 — Surrogate Endpoint (SUR): Blood pressure
Study 9647493 — Surrogate Endpoint (SUR): Blood pressure
Study 9647493 — Surrogate Endpoint (SUR): Serum creatinine
Study 9340029 — Surrogate Endpoint (SUR): Blood pressure
Study 2777011 — Surrogate Endpoint (SUR): Blood pressure
Study 24612734 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18718737 — Predictive Biomarker (PRD): SDC1 mRNA
Genes: SDC1; SDC
Study 24659064 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15892276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15892276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15262838 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9734727 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 3402466 — Surrogate Endpoint (SUR): Blood pressure
Study 3402466 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8336373 — Surrogate Endpoint (SUR): Blood pressure
Study 3459351 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3459351 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 3459351 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3459351 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19307503 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 19307503 — Safety Biomarker (SAF): MTHFR
Study 11134438 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 21295507 — Surrogate Endpoint (SUR): Bone mineral density
Study 21295507 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21295507 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16966690 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10699943 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 29530933 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 29530933 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29530933 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 29530933 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 19853420 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 19853420 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 7916403 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20594330 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 20594330 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9477056 — Surrogate Endpoint (SUR): Blood pressure
Study 7890075 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 1854108 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27687644 — Surrogate Endpoint (SUR): Blood pressure
Study 22137512 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15037490 — Surrogate Endpoint (SUR): Blood pressure
Study 21834489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8353046 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 8353046 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25801652 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21696241 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11728044 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8493292 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29676972 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25029008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25029008 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25029008 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 25029008 — Safety Biomarker (SAF): Interleukin 1
Study 16171665 — Safety Biomarker (SAF): IL-6 and IL-10
Study 19638647 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 821075 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 18339606 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 18339606 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18339606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18339606 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 3354431 — Surrogate Endpoint (SUR): Blood pressure
Study 28126600 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24689056 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 24689056 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16118079 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22166241 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30215545 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25027335 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 25027335 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25027335 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 15834239 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 10778622 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8580384 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8580384 — Safety Biomarker (SAF): Interleukin 1
Study 8580384 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8580384 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23778325 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 23778325 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study 23778325 — Predictive Biomarker (PRD): ALOX12 mRNA
Genes: ALOX12; 12LO; LOG12
Study 23778325 — Predictive Biomarker (PRD): PTGES mRNA
Genes: PTGES; MGST1L1; MPGES1; PGES; PIG12
Study 23778325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23778325 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 23778325 — Predictive Biomarker (PRD): GPX3 mRNA
Genes: GPX3; GPXP
Study 21262886 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 17324745 — Surrogate Endpoint (SUR): Blood pressure
Study 15054155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2658886 — Surrogate Endpoint (SUR): Blood pressure
Study 31819387 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26698120 — Surrogate Endpoint (SUR): Blood pressure
Study 24026599 — Surrogate Endpoint (SUR): Blood pressure
Study 12698670 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12698670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12698670 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8616947 — Surrogate Endpoint (SUR): Blood pressure
Study 1412677 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 2637586 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 29768118 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21778912 — Surrogate Endpoint (SUR): Blood pressure
Study 21778912 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16938161 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 16938161 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2035380 — Surrogate Endpoint (SUR): Blood pressure
Study 28252827 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 16322283 — Predictive Biomarker (PRD): ELAPOR1 mRNA
Genes: ELAPOR1; EIG121; KIAA1324; UNQ2426/PRO4985
Study 12081832 — Safety Biomarker (SAF): MTHFR
Study 7871564 — Surrogate Endpoint (SUR): Blood pressure
Study 27984005 — Surrogate Endpoint (SUR): Blood pressure
Study 3161422 — Surrogate Endpoint (SUR): Blood pressure
Study 29799668 — Predictive Biomarker (PRD): TKTL1 mRNA
Genes: TKTL1; TKR; TKT2
Study 19487582 — Surrogate Endpoint (SUR): Blood pressure
Study 3530447 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 3530447 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24650009 — Surrogate Endpoint (SUR): Bone mineral density
Study 12566361 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12566361 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 12566361 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10225081 — Surrogate Endpoint (SUR): Serum sodium
Study 29042662 — Monitoring Biomarker (MOI): HBV DNA
Study 22824097 — Surrogate Endpoint (SUR): Bone mineral density
Study 19615091 — Surrogate Endpoint (SUR): Blood pressure
Study 15073704 — Surrogate Endpoint (SUR): Blood pressure
Study 9509951 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 9509951 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27651218 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27651218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27651218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27651218 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10918423 — Predictive Biomarker (PRD): THPO mRNA
Genes: THPO; MGDF
Study 19927151 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study 19927151 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19927151 — Surrogate Endpoint (SUR): Blood pressure
Study 10663062 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 8851595 — Surrogate Endpoint (SUR): Serum creatinine
Study 22984233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20733134 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 9848502 — Surrogate Endpoint (SUR): Bone mineral density
Study 9848502 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 31129587 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 29525602 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29525602 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26404015 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 17261329 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 11669361 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20921462 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20921462 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 8614068 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9683043 — Surrogate Endpoint (SUR): Blood pressure
Study 26314389 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 21544559 — Surrogate Endpoint (SUR): Blood pressure
Study 18438876 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 10882619 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29450636 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 26826547 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11973420 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10361110 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8729953 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1710823 — Surrogate Endpoint (SUR): Blood pressure
Study 22338959 — Surrogate Endpoint (SUR): Bone mineral density
Study 16986228 — Surrogate Endpoint (SUR): Blood pressure
Study 30772975 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8530644 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 27745532 — Predictive Biomarker (PRD): VASH1 mRNA
Genes: VASH1; KIAA1036; VASH
Study 23115085 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 23115085 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study 23115085 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 31393378 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 18596668 — Surrogate Endpoint (SUR): Bone mineral density
Study 16926119 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15083986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9496526 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2647270 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30159779 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 30159779 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 30159779 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 30159779 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 25408735 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7586436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7586436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7586436 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22326504 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 22326504 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2994148 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2994148 — Surrogate Endpoint (SUR): Blood pressure
Study 30832742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30832742 — Safety Biomarker (SAF): Human leucocyte antigen
Study 20375405 — Surrogate Endpoint (SUR): Serum creatinine
Study 10843434 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28953631 — Surrogate Endpoint (SUR): Blood pressure
Study 3059852 — Surrogate Endpoint (SUR): Blood pressure
Study 24079465 — Surrogate Endpoint (SUR): Bone mineral density
Study 28623954 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28623954 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21185229 — Surrogate Endpoint (SUR): Blood pressure
Study 19695029 — Surrogate Endpoint (SUR): Blood pressure
Study 11986408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11986408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28467150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28467150 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16927283 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 3310159 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 7676778 — Surrogate Endpoint (SUR): Blood pressure