TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02110381 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01683188 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03386500 — Predictive Biomarker (PRD): BMX mRNA
Genes: BMX
Study NCT04237909 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00746759 — Predictive Biomarker (PRD): IDE mRNA
Genes: IDE
Study NCT01885559 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03650166 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02326220 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01620788 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02757911 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02500147 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study NCT00655499 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03140670 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT03450642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04284878 — Predictive Biomarker (PRD): PTPN22 mRNA
Genes: PTPN22; PTPN8
Study NCT04501744 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00760591 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00760591 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01064999 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01608113 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03944694 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT01227746 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01136512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02298556 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02298556 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03490032 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04463394 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01231178 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00081913 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02082652 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT03795688 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT02233556 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT01895114 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT02208843 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03331536 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02604693 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00407888 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04364230 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT01366742 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01253213 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT03154775 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04275960 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT01054859 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02109913 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02109913 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02721407 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT02721407 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT01275859 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01275859 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03652493 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00006045 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT00208273 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03278977 — Predictive Biomarker (PRD): ACHE mRNA
Genes: ACHE
Study NCT02561195 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00054938 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00880074 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01042184 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04012905 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study NCT05331872 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01144520 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03265756 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT00220805 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02802488 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT05191732 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05191732 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study NCT05191732 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01281436 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03963466 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00944541 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01540500 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT05405244 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT05405244 — Safety Biomarker (SAF): DRD2
Study NCT00075998 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01788371 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00822432 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study NCT01131546 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01529944 — Predictive Biomarker (PRD): PTPN11 mRNA
Genes: PTPN11; PTP2C; SHPTP2
Study NCT03765385 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02621541 — Predictive Biomarker (PRD): NOCT mRNA
Genes: NOCT; CCR4; CCRN4L; NOC
Study NCT01337752 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study NCT03863405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03863405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00467090 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT00608699 — Predictive Biomarker (PRD): HCAR2 mRNA
Genes: HCAR2; GPR109A; HCA2; HM74A; NIACR1
Study NCT02404844 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02404844 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02404844 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02074228 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study NCT01061307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03717207 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02234141 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT02234141 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02234141 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03080805 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01279707 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT02040870 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02969200 — Safety Biomarker (SAF): 51Cr-EDTA
Study NCT02590198 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03957850 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study NCT00231166 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT02060487 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02829008 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01781403 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT04315766 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT00143988 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00953355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00018018 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT00018018 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00711594 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00711594 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03978065 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT03978065 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study NCT03978065 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03868878 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03868878 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00005808 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01334840 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT01567007 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04156048 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04156048 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01589341 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study NCT00219193 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04873206 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT03018067 — Surrogate Endpoint (SUR): Serum potassium
Study NCT04705649 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study NCT04705649 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00489879 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01317966 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study NCT03836651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03430518 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03430518 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03146026 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT03146026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01128322 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00229034 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT02496559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00300404 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00825344 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00895596 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02640703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02640703 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT02640703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04093609 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04093609 — Predictive Biomarker (PRD): XIST
Study NCT04707807 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02656147 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00667017 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT03860454 — Predictive Biomarker (PRD): LMNA mRNA
Genes: LMNA; LMN1
Study NCT03999788 — Safety Biomarker (SAF): miR-142
Genes: MIR142
Study NCT00942344 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04365959 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01353274 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02431767 — Safety Biomarker (SAF): Interleukin 12
Study NCT02177825 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT04334252 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04224415 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02409043 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT02409043 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT02409043 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00022672 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00022672 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02136654 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02736188 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study NCT02747537 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT02747537 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT02263105 — Predictive Biomarker (PRD): GATM mRNA
Genes: GATM; AGAT
Study NCT02263105 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT05396365 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study NCT04181385 — Safety Biomarker (SAF): DRD2
Study NCT01443156 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03329950 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT02535221 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02535221 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02535221 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02065609 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04007705 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01846715 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT02624830 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study NCT04413994 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00920985 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04140292 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT00391170 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02540369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04987528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04987528 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03119740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04707820 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03809078 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03929198 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01604122 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT04745468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03679299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03392805 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03392805 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT03392805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02841449 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT01604824 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01604824 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01138384 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01138384 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03942094 — Surrogate Endpoint (SUR): Hematologic response
Study NCT03615833 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00110669 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04493359 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04493359 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05435131 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT05435131 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT00553332 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT03650543 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04377724 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00874588 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT00874588 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00874588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT03507244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04405310 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05266300 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study NCT02844959 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study NCT02844959 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study NCT02844959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03098199 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01217736 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01705756 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04254653 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00126958 — Predictive Biomarker (PRD): FGFR3 mRNA
Genes: FGFR3; JTK4
Study NCT02819999 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study NCT01439854 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02359929 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02752633 — Predictive Biomarker (PRD): APRT mRNA
Genes: APRT
Study NCT00777049 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00943969 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study NCT01130298 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT01582321 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01519141 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01709617 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study NCT02431442 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study NCT01698918 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01698918 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01698918 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01045512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01045512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01045512 — Safety Biomarker (SAF): Interleukin 1
Study NCT00849810 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00958048 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT05309057 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00250770 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00250770 — Safety Biomarker (SAF): Interleukin 1
Study NCT00250770 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02684656 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT01630486 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03807596 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02304757 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03726593 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT01794299 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03313726 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03335488 — Surrogate Endpoint (SUR): Plasma ammonia
Study NCT03696056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03696056 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT03696056 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03696056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01584648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT01933945 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT04602949 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01034488 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT04459572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04459572 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT04459572 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study NCT00068107 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT00068107 — Surrogate Endpoint (SUR): Blood pressure