TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8739928 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 8739928 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27418594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11788184 — Surrogate Endpoint (SUR): Bone mineral density
Study 22285857 — Surrogate Endpoint (SUR): Blood pressure
Study 27179738 — Surrogate Endpoint (SUR): Blood pressure
Study 22893166 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 27661412 — Safety Biomarker (SAF): miR-16
Study 27661412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27661412 — Predictive Biomarker (PRD): miR-106a
Genes: MIR106A
Study 27661412 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-223
Genes: MIR223
Study 27661412 — Safety Biomarker (SAF): miR-652
Genes: MIR652
Study 27661412 — Safety Biomarker (SAF): miR-18a
Genes: MIR18A
Study 14639584 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 31257591 — Predictive Biomarker (PRD): CST9 mRNA
Genes: CST9; CLM; CTES7A
Study 12042231 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 7762855 — Surrogate Endpoint (SUR): Blood pressure
Study 1702899 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 1702899 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1702899 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 1702899 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 1702899 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 1702899 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 1702899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1702899 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25596266 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 25596266 — Predictive Biomarker (PRD): FCGR2A mRNA
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 25596266 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 30388194 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 12532901 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12532901 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 12532901 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28349667 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 28349667 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 28349667 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 28349667 — Predictive Biomarker (PRD): CPT1B mRNA
Genes: CPT1B; KIAA1670
Study 24050377 — Surrogate Endpoint (SUR): Blood pressure
Study 17910386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17910386 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16254264 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 12440605 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10208143 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2515940 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27756786 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 27756786 — Predictive Biomarker (PRD): AMACR mRNA
Genes: AMACR
Study 29392002 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 14691415 — Surrogate Endpoint (SUR): Blood pressure
Study 22332908 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 22332908 — Predictive Biomarker (PRD): CCND2 mRNA
Genes: CCND2
Study 27803139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10826565 — Surrogate Endpoint (SUR): Blood pressure
Study 8858747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1515637 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27463412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27463412 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19609570 — Surrogate Endpoint (SUR): Blood pressure
Study 1906441 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 30902753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30902753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30902753 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23260261 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23260261 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17644340 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11233386 — Surrogate Endpoint (SUR): Blood pressure
Study 19262561 — Surrogate Endpoint (SUR): Bone mineral density
Study 16412224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16412224 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 25584002 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21523806 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 16935774 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 16935774 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 16935774 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29677687 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22305632 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12830442 — Surrogate Endpoint (SUR): Blood pressure
Study 30103738 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30103738 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 24910976 — Predictive Biomarker (PRD): FLCN mRNA
Genes: FLCN; BHD
Study 19133217 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19133217 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 16364669 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 14605526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14605526 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 14605526 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 14605526 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21592475 — Monitoring Biomarker (MOI): HBV DNA
Study 15090314 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 26250745 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 23878833 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 23878833 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 20568431 — Surrogate Endpoint (SUR): Bone mineral density
Study 1822255 — Surrogate Endpoint (SUR): Blood pressure
Study 20235224 — Predictive Biomarker (PRD): SHD mRNA
Genes: SHD
Study 12166344 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8292907 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE
Study 12536743 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 23303870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15983311 — Surrogate Endpoint (SUR): Blood pressure
Study 6335905 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 31462554 — Monitoring Biomarker (MOI): HBV DNA
Study 25680689 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 30208601 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30208601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30208601 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10449104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8960851 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8960851 — Surrogate Endpoint (SUR): Blood pressure
Study 24576401 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 24576401 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 24576401 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17986164 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 9707026 — Surrogate Endpoint (SUR): Serum creatinine
Study 6119685 — Surrogate Endpoint (SUR): Blood pressure
Study 6119685 — Surrogate Endpoint (SUR): Serum uric acid
Study 31713733 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28859947 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 8021578 — Surrogate Endpoint (SUR): Blood pressure
Study 2686488 — Surrogate Endpoint (SUR): Blood pressure
Study 25464260 — Surrogate Endpoint (SUR): Blood pressure
Study 27323347 — Surrogate Endpoint (SUR): Pathological complete response
Study 25939514 — Predictive Biomarker (PRD): ARVCF mRNA
Genes: ARVCF
Study 21095135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18240145 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 14610014 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 14610014 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 14610014 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14610014 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8817142 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 26787023 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26787023 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 19733931 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 19733931 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 19733931 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 1467386 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 17517342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9036306 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26290435 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 26290435 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 23104705 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11034431 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31877910 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 31877910 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 21877927 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8792921 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 22762147 — Surrogate Endpoint (SUR): Bone mineral density
Study 16279568 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 16279568 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 7930300 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21925942 — Surrogate Endpoint (SUR): Blood pressure
Study 24728665 — Surrogate Endpoint (SUR): Blood pressure
Study 21545606 — Predictive Biomarker (PRD): SLC10A2 mRNA
Genes: SLC10A2; ASBT; ISBT; NTCP2
Study 21545606 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 19644896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19644896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17380548 — Surrogate Endpoint (SUR): Serum creatinine
Study 25760679 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21362268 — Predictive Biomarker (PRD): MCM2 mRNA
Genes: MCM2; BM28; CCNL1; CDCL1; KIAA0030
Study 8027275 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 26580673 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21068341 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9500558 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2565687 — Surrogate Endpoint (SUR): Blood pressure
Study 28918754 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 28918754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28918754 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25038558 — Surrogate Endpoint (SUR): Blood pressure
Study 7917532 — Surrogate Endpoint (SUR): Serum calcium
Study 7917532 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 7917532 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 19769477 — Surrogate Endpoint (SUR): Blood pressure
Study 16784179 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16784179 — Surrogate Endpoint (SUR): Blood pressure
Study 23425564 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23425564 — Predictive Biomarker (PRD): Hormone receptor
Study 17465257 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27882820 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 27882820 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 24386809 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 24386809 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21481871 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21481871 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 21481871 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21481871 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21481871 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 19190265 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 25223844 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 23887901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16248380 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8259772 — Surrogate Endpoint (SUR): Bone mineral density
Study 29885375 — Predictive Biomarker (PRD): Hormone receptor
Study 28177189 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 15960556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30406819 — Surrogate Endpoint (SUR): Blood pressure
Study 22927115 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 19534294 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 14760320 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14760320 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9549270 — Surrogate Endpoint (SUR): Blood pressure
Study 2656774 — Surrogate Endpoint (SUR): Blood pressure
Study 21413940 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 19188680 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12575547 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1703327 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 17922461 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 17922461 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 16135353 — Surrogate Endpoint (SUR): Blood pressure
Study 12161491 — Surrogate Endpoint (SUR): Bone mineral density
Study 10434215 — Surrogate Endpoint (SUR): Serum creatinine
Study 23554029 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23554029 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17967583 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 7622850 — Surrogate Endpoint (SUR): Blood pressure
Study 22589376 — Predictive Biomarker (PRD): CCR1 mRNA
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 22589376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11391320 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9578521 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7526056 — Surrogate Endpoint (SUR): Blood pressure
Study 29321134 — Surrogate Endpoint (SUR): Blood pressure
Study 29321134 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22731679 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22731679 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19795993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18378030 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 10525492 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1013693 — Surrogate Endpoint (SUR): Blood pressure
Study 28582885 — Predictive Biomarker (PRD): PNMA2 mRNA
Genes: PNMA2; KIAA0883; MA2
Study 21592370 — Surrogate Endpoint (SUR): Pathological complete response
Study 11338763 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study 9212125 — Surrogate Endpoint (SUR): Blood pressure
Study 31780201 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31780201 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 14691426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14691426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14691426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8310991 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3337484 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27569003 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 26677669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1323926 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 6507905 — Surrogate Endpoint (SUR): Blood pressure
Study 6507905 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20939113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20939113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20939113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10372241 — Surrogate Endpoint (SUR): Blood pressure
Study 31928474 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24154863 — Predictive Biomarker (PRD): RNH1 mRNA
Genes: RNH1; PRI; RNH
Study 24154863 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 20854964 — Surrogate Endpoint (SUR): Blood pressure
Study 30540701 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 22248750 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16336059 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16336059 — Surrogate Endpoint (SUR): Blood pressure
Study 11887131 — Surrogate Endpoint (SUR): Blood pressure
Study 2195704 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26887213 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23359185 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22097348 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30115007 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 21087499 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14501856 — Surrogate Endpoint (SUR): Serum creatinine
Study 8794438 — Surrogate Endpoint (SUR): Bone mineral density
Study 8794438 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31157663 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24675102 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17919549 — Surrogate Endpoint (SUR): Bone mineral density
Study 1771968 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29986268 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 28427456 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 14613435 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 21699953 — Safety Biomarker (SAF): Reactive oxygen species
Study 21699953 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10959482 — Monitoring Biomarker (MOI): HBV DNA
Study 1284331 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 17925417 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8794822 — Surrogate Endpoint (SUR): Blood pressure