TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT03889080 — Predictive Biomarker (PRD): SCN9A mRNA
Genes: SCN9A; NENA
Study NCT01030900 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT01030900 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02744456 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02557997 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT02557997 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study NCT02557997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02557997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00549055 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01978158 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT03240016 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03240016 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02838420 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01200680 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT01788982 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01788982 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01788982 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01788982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03351270 — Predictive Biomarker (PRD): MTM1 mRNA
Genes: MTM1; CG2
Study NCT03351270 — Predictive Biomarker (PRD): DNM2 mRNA
Genes: DNM2; DYN2
Study NCT04131738 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT00855543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06552221 — Predictive Biomarker (PRD): CKS1B mRNA
Genes: CKS1B; CKS1; PNAS-143; PNAS-16
Study NCT06552221 — Predictive Biomarker (PRD): CDKN2C mRNA
Genes: CDKN2C; CDKN6
Study NCT00468832 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00685776 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03437837 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03437837 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03437837 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04706377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT06374719 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study NCT01853800 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00641615 — Predictive Biomarker (PRD): RNF43 mRNA
Genes: RNF43
Study NCT03050216 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02523014 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH
Study NCT02523014 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT02523014 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT00542308 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02191644 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT04375124 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00193648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02369198 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02369198 — Safety Biomarker (SAF): miR-16
Study NCT00189930 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04069858 — Monitoring Biomarker (MOI): HBV DNA
Study NCT02764736 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01033331 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT04948918 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04243616 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04243616 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04243616 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04243616 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04243616 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03935438 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT03935438 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study NCT03935438 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03935438 — Predictive Biomarker (PRD): LEPR mRNA
Genes: LEPR; DB; OBR
Study NCT03935438 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03935438 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02834273 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04204473 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04204473 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04952818 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT04952818 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04952818 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study NCT04952818 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01653717 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01653717 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02987452 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02987452 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT01137994 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01982448 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT05937737 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT01771458 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03637686 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01546285 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01541267 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03991884 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT01926210 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study NCT04391816 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03128021 — Predictive Biomarker (PRD): IKBKG mRNA
Genes: IKBKG; FIP3; NEMO
Study NCT02479490 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03696433 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02640144 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01396239 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01114373 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03668392 — Surrogate Endpoint (SUR): Serum asparaginase
Study NCT04146376 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04495621 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04495621 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04495621 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03302897 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study NCT03448393 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03448393 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT03497442 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study NCT03927638 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05984446 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT03518606 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03087071 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00148798 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00148798 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT06337682 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02373241 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04040699 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00835419 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study NCT02347150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01345799 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT01951950 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01791270 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03249831 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00984867 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00984867 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04912999 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04608435 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT02433717 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT02433717 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02433717 — Predictive Biomarker (PRD): RGS4 mRNA
Genes: RGS4
Study NCT02433717 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT01777646 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01946945 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT02152254 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT04545736 — Predictive Biomarker (PRD): ABCA4 mRNA
Genes: ABCA4; ABCR
Study NCT03493867 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02263495 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01856933 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02299999 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02593240 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03609021 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02740634 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT04752059 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03765983 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03095053 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study NCT00794508 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT02794870 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02882308 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study NCT02040441 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02208739 — Surrogate Endpoint (SUR): Bacterial count
Study NCT02208739 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT01928849 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT04229667 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02065557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03531905 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03083678 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01051947 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03025204 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study NCT03323762 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03823625 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03823625 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03823625 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04802044 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04802044 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04556071 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study NCT00425373 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01459042 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT04260087 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04510168 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02264912 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study NCT03742596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03742596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03742596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03742596 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT03742596 — Safety Biomarker (SAF): Interleukin 1
Study NCT03742596 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03336346 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT01298258 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03147963 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03056924 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05249452 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04792762 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00576446 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03267901 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03267901 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02070406 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01841138 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01841138 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02865460 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01855828 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01021280 — Predictive Biomarker (PRD): CASR mRNA
Genes: CASR; GPRC2A; PCAR1
Study NCT04613492 — Safety Biomarker (SAF): Interleukin 12
Study NCT03756675 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03756675 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02826512 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02826512 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00879411 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01532089 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01532089 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01377012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00005175 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04739098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03007238 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03007238 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00004137 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02056912 — Predictive Biomarker (PRD): AGPAT2 mRNA
Genes: AGPAT2
Study NCT02056912 — Predictive Biomarker (PRD): LMNA mRNA
Genes: LMNA; LMN1
Study NCT00031343 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03968341 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02006225 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT03747003 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT03874273 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03874273 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT00043628 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00340678 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04590352 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03203681 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02125721 — Surrogate Endpoint (SUR): Urinary cystine
Study NCT04204057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04240873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03886883 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT02077361 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study NCT00920790 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study NCT03727880 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT01534130 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT01124240 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT04539652 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00551018 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02467478 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02467478 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01954745 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01954745 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT03978767 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03765788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03035929 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study NCT03035929 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study NCT03035929 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03020589 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT02335918 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study NCT03389815 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03389815 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT03389815 — Predictive Biomarker (PRD): ALK
Genes: CD246; ALK1
Study NCT03011450 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03452787 — Predictive Biomarker (PRD): APOA2 mRNA
Genes: APOA2
Study NCT03311750 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03311750 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03311750 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03665545 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT04202055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04202055 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT04202055 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT04202055 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT04202055 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT00880789 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01614704 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00097227 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01130597 — Surrogate Endpoint (SUR): Serum potassium
Study NCT04167540 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study NCT02794246 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02335944 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01806493 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01806493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03623347 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03691532 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study NCT03503045 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00339885 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03737422 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00627861 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00627861 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01266031 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01266031 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03526159 — Predictive Biomarker (PRD): Laminin subunit alpha-3
Genes: LAMA3; LAMNA
Study NCT03526159 — Predictive Biomarker (PRD): LAMB3 mRNA
Genes: LAMB3; LAMNB1