TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18713548 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 18713548 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17065354 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 10910888 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10910888 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 10910888 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1568692 — Surrogate Endpoint (SUR): Blood pressure
Study 30059843 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30059843 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26033126 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 26033126 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 14614579 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 9397236 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9397236 — Surrogate Endpoint (SUR): Blood pressure
Study 7966514 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29402521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19159590 — Predictive Biomarker (PRD): KIR2DL3 mRNA
Genes: KIR2DL3; CD158B2; KIRCL23; NKAT2
Study 19159590 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 8314499 — Monitoring Biomarker (MOI): HBV DNA
Study 2876497 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 19056135 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19056135 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19056135 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 19056135 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 10826412 — Surrogate Endpoint (SUR): Blood pressure
Study 26914986 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21807638 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21807638 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21590466 — Surrogate Endpoint (SUR): Serum creatinine
Study 24297949 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 9042123 — Surrogate Endpoint (SUR): Blood pressure
Study 23335089 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21741804 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21741804 — Safety Biomarker (SAF): BDNF
Study 15324486 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 3553492 — Surrogate Endpoint (SUR): Blood pressure
Study 31992840 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study 31992840 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 31992840 — Predictive Biomarker (PRD): JAK3 mRNA
Genes: JAK3
Study 31992840 — Predictive Biomarker (PRD): STAT5B mRNA
Genes: STAT5B
Study 28320081 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25425058 — Surrogate Endpoint (SUR): Blood pressure
Study 30730838 — Surrogate Endpoint (SUR): Blood pressure
Study 17563214 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 12145915 — Surrogate Endpoint (SUR): Blood pressure
Study 11913409 — Surrogate Endpoint (SUR): Blood pressure
Study 31093662 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 27933333 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25331843 — Surrogate Endpoint (SUR): Blood pressure
Study 19301378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 29926653 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29926653 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 29926653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7698030 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7698030 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7698030 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24156019 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 17971715 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6747766 — Surrogate Endpoint (SUR): Blood pressure
Study 27658873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10080612 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 7742676 — Surrogate Endpoint (SUR): Blood pressure
Study 9582556 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 7812699 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28853979 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 28498501 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 11220553 — Surrogate Endpoint (SUR): Blood pressure
Study 9123738 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 9123738 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27245783 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 19119067 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19119067 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18087561 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18087561 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18087561 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24451221 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 11904593 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10935831 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31806543 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31806543 — Predictive Biomarker (PRD): Hormone receptor
Study 26634615 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 26634615 — Surrogate Endpoint (SUR): Blood pressure
Study 31325379 — Predictive Biomarker (PRD): CPT1A mRNA
Genes: CPT1A; CPT1
Study 30621105 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 30621105 — Surrogate Endpoint (SUR): Serum uric acid
Study 30621105 — Surrogate Endpoint (SUR): Blood pressure
Study 23064222 — Predictive Biomarker (PRD): BOC mRNA
Genes: BOC; UNQ604/PRO1190
Study 16281636 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 9327830 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18548088 — Surrogate Endpoint (SUR): Blood pressure
Study 23118893 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9847269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9847269 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17077421 — Surrogate Endpoint (SUR): Blood pressure
Study 17077421 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9496009 — Predictive Biomarker (PRD): F10 mRNA
Genes: F10
Study 3372432 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10073421 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31836196 — Surrogate Endpoint (SUR): Blood pressure
Study 12114917 — Surrogate Endpoint (SUR): Blood pressure
Study 7586985 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31661171 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 29104459 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 29104459 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 29104459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29104459 — Predictive Biomarker (PRD): UVRAG mRNA
Genes: UVRAG
Study 29104459 — Predictive Biomarker (PRD): SQSTM1 mRNA
Genes: SQSTM1; ORCA; OSIL
Study 29104459 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 23440253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23440253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19524329 — Surrogate Endpoint (SUR): Blood pressure
Study 8546911 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 8546911 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 1884746 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31525174 — Surrogate Endpoint (SUR): Blood pressure
Study 29370756 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 22045039 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 29190605 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 17473001 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 17473001 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 7993161 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25434574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25434574 — Surrogate Endpoint (SUR): Blood pressure
Study 25434574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14743580 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1349492 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1349492 — Surrogate Endpoint (SUR): Blood pressure
Study 25135729 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 17912637 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17912637 — Predictive Biomarker (PRD): Hormone receptor
Study 2597598 — Surrogate Endpoint (SUR): Blood pressure
Study 29805491 — Monitoring Biomarker (MOI): Procalcitonin
Study 29805491 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12040355 — Surrogate Endpoint (SUR): Serum creatinine
Study 10069278 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30719237 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 25496958 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 20853602 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15338100 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27662551 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8757561 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8757561 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 1550481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1550481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16765589 — Predictive Biomarker (PRD): Hormone receptor
Study 1958387 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26258860 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 26258860 — Surrogate Endpoint (SUR): Blood pressure
Study 11588120 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 11588120 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31453902 — Safety Biomarker (SAF): Hyaluronic acid
Study 31504139 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31504139 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 26409117 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 19173846 — Surrogate Endpoint (SUR): Blood pressure
Study 29455305 — Safety Biomarker (SAF): Reactive oxygen species
Study 27578220 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 23939415 — Surrogate Endpoint (SUR): Blood pressure
Study 18257143 — Surrogate Endpoint (SUR): Bone mineral density
Study 8864317 — Predictive Biomarker (PRD): ASPRV1 mRNA
Genes: ASPRV1; SASP
Study 8864317 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15653291 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 30106636 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30106636 — Predictive Biomarker (PRD): Hormone receptor
Study 27401244 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 31489650 — Surrogate Endpoint (SUR): Blood pressure
Study 28723843 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 25355640 — Predictive Biomarker (PRD): XRCC2 mRNA
Genes: XRCC2
Study 11291296 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 23782622 — Surrogate Endpoint (SUR): Blood pressure
Study 21346095 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18501066 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18501066 — Predictive Biomarker (PRD): Hormone receptor
Study 18501066 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17575805 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10894877 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30077574 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11788642 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6785790 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 21894690 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8393637 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 26901242 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26901242 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26901242 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12225549 — Surrogate Endpoint (SUR): Blood pressure
Study 9857278 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7883833 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 21609212 — Safety Biomarker (SAF): Hyaluronic acid
Study 30191781 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 28225313 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28225313 — Surrogate Endpoint (SUR): Serum testosterone
Study 19114909 — Surrogate Endpoint (SUR): Serum creatinine
Study 10483132 — Surrogate Endpoint (SUR): Blood pressure
Study 2193640 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25919061 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27187451 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27187451 — Surrogate Endpoint (SUR): Blood pressure
Study 20184572 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 31427862 — Surrogate Endpoint (SUR): Blood pressure
Study 31427862 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24526141 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 23964444 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 23964444 — Safety Biomarker (SAF): Interleukin 1
Study 23964444 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20185666 — Surrogate Endpoint (SUR): Serum sodium
Study 17657838 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15662503 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11792748 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22950641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22950641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22950641 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22950641 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17517832 — Monitoring Biomarker (MOI): HBV DNA
Study 11481357 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11481357 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28446376 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 26042933 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15617458 — Surrogate Endpoint (SUR): Blood pressure
Study 11320384 — Surrogate Endpoint (SUR): Blood pressure
Study 19586971 — Surrogate Endpoint (SUR): Blood pressure
Study 9800180 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 24239156 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 3089491 — Surrogate Endpoint (SUR): Blood pressure
Study 11109313 — Surrogate Endpoint (SUR): Blood pressure
Study 9195357 — Surrogate Endpoint (SUR): Blood pressure
Study 30269900 — Surrogate Endpoint (SUR): Serum creatinine
Study 27327024 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 27327024 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27327024 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 27327024 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 24293578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24293578 — Safety Biomarker (SAF): Interleukin 1
Study 24293578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12822009 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 7867183 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25828994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23713032 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16733237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16733237 — Surrogate Endpoint (SUR): Blood pressure
Study 16733237 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25678098 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21921249 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 16978997 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16978997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16978997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6859790 — Surrogate Endpoint (SUR): Blood pressure
Study 15893293 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 28915981 — Predictive Biomarker (PRD): SP8 mRNA
Genes: SP8
Study 28915981 — Predictive Biomarker (PRD): CA1 mRNA
Genes: CA1
Study 28915981 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 22836615 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 14648009 — Surrogate Endpoint (SUR): Bone mineral density
Study 31108918 — Surrogate Endpoint (SUR): Blood pressure
Study 16447105 — Surrogate Endpoint (SUR): Serum creatinine
Study 1738926 — Surrogate Endpoint (SUR): Serum creatinine
Study 25060541 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16416642 — Safety Biomarker (SAF): Hyaluronic acid
Study 10530413 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 31444180 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1331443 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1331443 — Surrogate Endpoint (SUR): Blood pressure
Study 18664303 — Surrogate Endpoint (SUR): Blood pressure
Study 12118026 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12118026 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 8710065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30277850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11907491 — Surrogate Endpoint (SUR): Blood pressure
Study 1915205 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28490565 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26062822 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 19770395 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9566654 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25955225 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 25955225 — Surrogate Endpoint (SUR): Serum calcium
Study 25955225 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 19402938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19402938 — Surrogate Endpoint (SUR): Blood pressure
Study 19402938 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19402938 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9683400 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2974769 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2974769 — Surrogate Endpoint (SUR): Blood pressure
Study 28012242 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 16571285 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 9175690 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9175690 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 20347369 — Surrogate Endpoint (SUR): Bone mineral density
Study 9373766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3894279 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15373933 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 21224289 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 16036075 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8738691 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 1540597 — Surrogate Endpoint (SUR): Serum creatinine
Study 20374034 — Predictive Biomarker (PRD): SOBP mRNA
Genes: SOBP; JXC1
Study 20374034 — Predictive Biomarker (PRD): RAB4A mRNA
Genes: RAB4A; RAB4
Study 20374034 — Predictive Biomarker (PRD): Hormone receptor