TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29498296 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 29498923 — Predictive Biomarker (PRD): IKZF1 mRNA
Genes: IKZF1; IK1; IKAROS; LYF1; ZNFN1A1
Study 29498923 — Predictive Biomarker (PRD): PAX5 mRNA
Genes: PAX5
Study 29498923 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 29498923 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 29498923 — Predictive Biomarker (PRD): BTG1 mRNA
Genes: BTG1
Study 29498923 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 29498923 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study 29498923 — Predictive Biomarker (PRD): CDKN2B mRNA
Genes: CDKN2B; MTS2
Study 29498923 — Predictive Biomarker (PRD): CRLF2 mRNA
Genes: CRLF2; CRL2; ILXR; TSLPR
Study 29499645 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 29499723 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29500138 — Monitoring Biomarker (MOI): Cell-free DNA
Study 29501599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29502530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29502530 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29504262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 29504262 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 29506157 — Surrogate Endpoint (SUR): Bone mineral density
Study 29506392 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29506523 — Surrogate Endpoint (SUR): Blood pressure
Study 29506984 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29506984 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29506988 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29506988 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 29507077 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 29507099 — Surrogate Endpoint (SUR): Blood pressure
Study 29507732 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 29508095 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29509546 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 29510707 — Surrogate Endpoint (SUR): Blood pressure
Study 29510707 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29510755 — Predictive Biomarker (PRD): AP5B1 mRNA
Genes: AP5B1; PP1030
Study 29510755 — Predictive Biomarker (PRD): RREB1 mRNA
Genes: RREB1; FINB
Study 29510755 — Predictive Biomarker (PRD): OBSCN mRNA
Genes: OBSCN; KIAA1556; KIAA1639
Study 29510755 — Predictive Biomarker (PRD): DNAH11 mRNA
Genes: DNAH11
Study 29510755 — Predictive Biomarker (PRD): IDO2 mRNA
Genes: IDO2; INDOL1
Study 29510755 — Predictive Biomarker (PRD): IGSF3 mRNA
Genes: IGSF3; EWI3; KIAA0466
Study 29510755 — Predictive Biomarker (PRD): KNL1 mRNA
Genes: KNL1; CASC5; KIAA1570
Study 29511132 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 29512061 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 29514256 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29514604 — Monitoring Biomarker (MOI): Procalcitonin
Study 29514604 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29514604 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29514648 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29514648 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 29514663 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29514773 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 29514815 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 29515114 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 29515114 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study 29515114 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 29515114 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 29517122 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29517122 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 29517122 — Surrogate Endpoint (SUR): Blood pressure
Study 29518553 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29519925 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 29522089 — Predictive Biomarker (PRD): HDGFL2 mRNA
Genes: HDGFL2; HDGF2; HDGFRP2; HRP2; UNQ785/PRO1604
Study 29522186 — Surrogate Endpoint (SUR): Blood pressure
Study 29522361 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29523169 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 29523171 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 29524090 — Surrogate Endpoint (SUR): Blood pressure
Study 29527344 — Surrogate Endpoint (SUR): Blood pressure
Study 29529007 — Surrogate Endpoint (SUR): Serum creatinine
Study 29529147 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 29530274 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29530667 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29530935 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29530989 — Surrogate Endpoint (SUR): Blood pressure
Study 29531651 — Predictive Biomarker (PRD): SLAMF7 mRNA
Genes: SLAMF7; CS1; UNQ576/PRO1138
Study 29531651 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 29531784 — Surrogate Endpoint (SUR): Serum uric acid
Study 29531837 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29531837 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29531839 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29531839 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29532243 — Surrogate Endpoint (SUR): Bone mineral density
Study 29533369 — Predictive Biomarker (PRD): TACR3 mRNA
Genes: TACR3; NK3R; TAC3R
Study 29533458 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29533458 — Predictive Biomarker (PRD); Safety Biomarker (SAF): EGFR
Genes: ERBB1; ERRP
Study 29533755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29534171 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 29534198 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 29534721 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29535712 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 29535869 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 29536210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29536210 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 29536526 — Surrogate Endpoint (SUR): Platelet count response
Study 29538669 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29540427 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29540575 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 29541969 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 29543932 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 29544445 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29544454 — Predictive Biomarker (PRD): S100A4 mRNA
Genes: S100A4; CAPL; MTS1
Study 29544547 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 29544699 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 29545095 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29545095 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29545283 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 29546316 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 29546316 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 29546316 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 29546316 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29548277 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 29548277 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 29548300 — Surrogate Endpoint (SUR): Bone mineral density
Study 29548934 — Surrogate Endpoint (SUR): Blood pressure
Study 29549159 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 29550316 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 29550382 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 29551338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29551711 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29551775 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 29551893 — Predictive Biomarker (PRD): SFRP5 mRNA
Genes: SFRP5; FRP1B; SARP3
Study 29553382 — Predictive Biomarker (PRD): ATXN1 mRNA
Genes: ATXN1; ATX1; SCA1
Study 29553382 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study 29553382 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 29553852 — Surrogate Endpoint (SUR): Blood pressure
Study 29553852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29554265 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 29555305 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 29556416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29556418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29556418 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 29556418 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 29556418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29556418 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 29556418 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29556418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29558274 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 29559561 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29559561 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29559773 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29560093 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29561066 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29561296 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29561296 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29562855 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29563634 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29565424 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 29565424 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29566106 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 29566186 — Predictive Biomarker (PRD): TLR1 mRNA
Genes: TLR1; KIAA0012
Study 29566186 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 29566186 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 29566186 — Predictive Biomarker (PRD): TLR10 mRNA
Genes: TLR10; UNQ315/PRO358
Study 29566186 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29566186 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 29566186 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 29566186 — Predictive Biomarker (PRD): NFKB1 mRNA
Genes: NFKB1
Study 29566195 — Safety Biomarker (SAF): MTHFR
Study 29566699 — Predictive Biomarker (PRD): PSMA4 mRNA
Genes: PSMA4; HC9; PSC9
Study 29566699 — Predictive Biomarker (PRD): EGLN2 mRNA
Genes: EGLN2; EIT6
Study 29566699 — Predictive Biomarker (PRD): WNT3 mRNA
Genes: WNT3; INT4
Study 29566699 — Predictive Biomarker (PRD): DCBLD1 mRNA
Genes: DCBLD1
Study 29566762 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29567071 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): GZMB mRNA
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 29567071 — Predictive Biomarker (PRD): WARS1 mRNA
Genes: WARS1; IFI53; WARS; WRS
Study 29567071 — Predictive Biomarker (PRD): SFRP4 mRNA
Genes: SFRP4; FRPHE
Study 29567071 — Predictive Biomarker (PRD): CDX1 mRNA
Genes: CDX1
Study 29567632 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 29567632 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29567632 — Predictive Biomarker (PRD): FOXO1 mRNA
Genes: FOXO1; FKHR; FOXO1A
Study 29567785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29567798 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 29568374 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study 29568762 — Surrogate Endpoint (SUR): Blood pressure
Study 29570971 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 29570971 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 29570971 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 29570971 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29570971 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29570971 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29571601 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29571946 — Predictive Biomarker (PRD): CSF1 mRNA
Genes: CSF1
Study 29571946 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 29573889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29573889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29574070 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 29574070 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29575698 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 29578250 — Surrogate Endpoint (SUR): Blood pressure
Study 29579325 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 29579325 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 29579331 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29579370 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29579597 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 29579607 — Surrogate Endpoint (SUR): Blood pressure
Study 29580174 — Surrogate Endpoint (SUR): Serum uric acid
Study 29581554 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29581554 — Surrogate Endpoint (SUR): Blood pressure
Study 29584545 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29587656 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29587677 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 29587759 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 29587840 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29588304 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29590311 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 29590318 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29590318 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29590318 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 29590335 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29590401 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 29590547 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 29590547 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 29590547 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 29593024 — Surrogate Endpoint (SUR): Blood pressure
Study 29593099 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 29594435 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 29594435 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29594970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29596029 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 29596029 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 29596029 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 29599530 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29601264 — Surrogate Endpoint (SUR): Blood pressure
Study 29601264 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29601268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29603015 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 29603764 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29604189 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29605405 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29605405 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29605813 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29606415 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 29606415 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29606586 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 29606586 — Predictive Biomarker (PRD): NTRK2 mRNA
Genes: NTRK2; TRKB
Study 29606586 — Predictive Biomarker (PRD): NTRK3 mRNA
Genes: NTRK3; TRKC
Study 29607050 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29608508 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 29608587 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29608711 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29608809 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29609013 — Predictive Biomarker (PRD): IL17F
Genes: IL-17F; ML-1; ML1
Study 29609532 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 29609532 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 29609536 — Surrogate Endpoint (SUR): Serum sodium
Study 29609555 — Surrogate Endpoint (SUR): Blood pressure
Study 29609706 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 29609868 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 29609868 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 29609868 — Predictive Biomarker (PRD): SELENOS mRNA
Genes: SELENOS; SELS; VIMP; AD-015; SBBI8
Study 29609867 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 29610121 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 29610943 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 29611022 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 29611022 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 29613921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29614389 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 29614955 — Predictive Biomarker (PRD): ELN mRNA
Genes: ELN
Study 29614983 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 29615082 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29617822 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 29619634 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 29621747 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 29622045 — Predictive Biomarker (PRD): COTL1 mRNA
Genes: COTL1; CLP
Study 29622755 — Surrogate Endpoint (SUR): Serum uric acid
Study 29622755 — Surrogate Endpoint (SUR): Blood pressure
Study 29622755 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29622755 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29623105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29623105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29623586 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29625571 — Surrogate Endpoint (SUR): Blood pressure
Study 29626424 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO