TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31865336 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31865336 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31865336 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21878067 — Surrogate Endpoint (SUR): Blood pressure
Study 21878067 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12525260 — Surrogate Endpoint (SUR): Serum testosterone
Study 30583542 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 23327881 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23327881 — Surrogate Endpoint (SUR): Serum creatinine
Study 16189764 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 11823664 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 23843881 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 18952082 — Predictive Biomarker (PRD): MTOR mRNA
Genes: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Study 11213534 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3969876 — Surrogate Endpoint (SUR): Blood pressure
Study 26773737 — Surrogate Endpoint (SUR): Blood pressure
Study 12383815 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 794022 — Surrogate Endpoint (SUR): Blood pressure
Study 28235493 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 17894896 — Surrogate Endpoint (SUR): Serum creatinine
Study 3291529 — Surrogate Endpoint (SUR): Blood pressure
Study 22563215 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 19017764 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 25407798 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25407798 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16159809 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16159809 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31159750 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31159750 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26012783 — Surrogate Endpoint (SUR): Blood pressure
Study 9390335 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9390335 — Surrogate Endpoint (SUR): Serum calcium
Study 12522893 — Surrogate Endpoint (SUR): Blood pressure
Study 30340505 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30340505 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30340505 — Predictive Biomarker (PRD): Hormone receptor
Study 18417963 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18417963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12431854 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30167807 — Surrogate Endpoint (SUR): Blood pressure
Study 15579724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 7607199 — Surrogate Endpoint (SUR): Blood pressure
Study 18547287 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 18547287 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study 18547287 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 18547287 — Predictive Biomarker (PRD): MUC4 mRNA
Genes: MUC4
Study 22170807 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19875277 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10232443 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 27631091 — Surrogate Endpoint (SUR): New morphometric vertebral fractures
Study 27631091 — Surrogate Endpoint (SUR): Bone mineral density
Study 26458336 — Surrogate Endpoint (SUR): Serum uric acid
Study 25675721 — Surrogate Endpoint (SUR): Blood pressure
Study 25303096 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8308716 — Surrogate Endpoint (SUR): Blood pressure
Study 29746376 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16309684 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 12775735 — Predictive Biomarker (PRD): Hormone receptor
Study 29767743 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29767743 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 29767743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31565781 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22745272 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24016248 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24016248 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18596116 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15764730 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 15764730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15764730 — Safety Biomarker (SAF): Reactive oxygen species
Study 22136711 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24675910 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 22089177 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16645532 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 6762167 — Surrogate Endpoint (SUR): Blood pressure
Study 29370424 — Surrogate Endpoint (SUR): Blood pressure
Study 29370424 — Surrogate Endpoint (SUR): Serum creatinine
Study 25559494 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 25559494 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 25559494 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25559494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16601362 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 10754612 — Predictive Biomarker (PRD): PPIA mRNA
Genes: PPIA; CYPA
Study 3908125 — Surrogate Endpoint (SUR): Blood pressure
Study 3908125 — Surrogate Endpoint (SUR): Serum potassium
Study 3908125 — Surrogate Endpoint (SUR): Serum sodium
Study 15957830 — Surrogate Endpoint (SUR): Serum creatinine
Study 7552524 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7552524 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25381629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25381629 — Safety Biomarker (SAF): Reactive oxygen species
Study 25381629 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10883412 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10883412 — Surrogate Endpoint (SUR): Blood pressure
Study 24720919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24720919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11641310 — Surrogate Endpoint (SUR): Blood pressure
Study 9588696 — Surrogate Endpoint (SUR): Blood pressure
Study 31113932 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 31113932 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 25433580 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 25433580 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25433580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25433580 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25433580 — Safety Biomarker (SAF): Interleukin 1
Study 25433580 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25015740 — Predictive Biomarker (PRD): Hormone receptor
Study 10880799 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10880799 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 6106148 — Surrogate Endpoint (SUR): Blood pressure
Study 24613434 — Surrogate Endpoint (SUR): Blood pressure
Study 24613434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24613434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22804104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8948610 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7768073 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 2382605 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31898874 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19779491 — Surrogate Endpoint (SUR): Blood pressure
Study 30792342 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29086478 — Surrogate Endpoint (SUR): Blood pressure
Study 29086478 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 25637602 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 25637602 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25637602 — Predictive Biomarker (PRD): MYH6 mRNA
Genes: MYH6; MYHCA
Study 25637602 — Predictive Biomarker (PRD): ATP2A2 mRNA
Genes: ATP2A2; ATP2B
Study 25637602 — Predictive Biomarker (PRD): PLN mRNA
Genes: PLN; PLB
Study 25637602 — Predictive Biomarker (PRD): RYR2 mRNA
Genes: RYR2
Study 25637602 — Predictive Biomarker (PRD): ADRA1D mRNA
Genes: ADRA1D; ADRA1A
Study 25637602 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 25637602 — Predictive Biomarker (PRD): MYL3 mRNA
Genes: MYL3
Study 25637602 — Predictive Biomarker (PRD): PDHX mRNA
Genes: PDHX; PDX1
Study 25637602 — Predictive Biomarker (PRD): CPT1B mRNA
Genes: CPT1B; KIAA1670
Study 16962720 — Surrogate Endpoint (SUR): Blood pressure
Study 25053587 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 9086127 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29361981 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22969845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17713431 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15075539 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11838566 — Surrogate Endpoint (SUR): Blood pressure
Study 9483586 — Safety Biomarker (SAF): Th2 cell
Study 23886280 — Predictive Biomarker (PRD): PITRM1 mRNA
Genes: PITRM1; KIAA1104; MP1; PREP
Study 12716689 — Surrogate Endpoint (SUR): Bone mineral density
Study 1574976 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 29576369 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25077916 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 25077916 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 19535219 — Safety Biomarker (SAF): Hyaluronic acid
Study 12909505 — Surrogate Endpoint (SUR): Bone mineral density
Study 6349668 — Surrogate Endpoint (SUR): Blood pressure
Study 17397305 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 15086925 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15086925 — Surrogate Endpoint (SUR): Serum creatinine
Study 15086925 — Surrogate Endpoint (SUR): Blood pressure
Study 15086925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19189 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 31911130 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26406293 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 21540233 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 23296097 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 8489354 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28007133 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 25876338 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21557265 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 20536517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19856616 — Surrogate Endpoint (SUR): Blood pressure
Study 3293872 — Surrogate Endpoint (SUR): Blood pressure
Study 28220486 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25332252 — Predictive Biomarker (PRD): Hormone receptor
Study 25332252 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21478777 — Surrogate Endpoint (SUR): Blood pressure
Study 18855558 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30239830 — Predictive Biomarker (PRD): FUT2 mRNA
Genes: FUT2; SEC2
Study 11149624 — Surrogate Endpoint (SUR): Blood pressure
Study 20822968 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 20822968 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 20822968 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15848713 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28618724 — Surrogate Endpoint (SUR): Blood pressure
Study 12877903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12877903 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12877903 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25968470 — Surrogate Endpoint (SUR): Blood pressure
Study 17003295 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17003295 — Surrogate Endpoint (SUR): Serum creatinine
Study 15302082 — Surrogate Endpoint (SUR): Serum creatinine
Study 18299694 — Surrogate Endpoint (SUR): Bone mineral density
Study 9366102 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9366102 — Surrogate Endpoint (SUR): Blood pressure
Study 416322 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2147909 — Surrogate Endpoint (SUR): Blood pressure
Study 28183547 — Predictive Biomarker (PRD): PSG1 mRNA
Genes: PSG1; B1G1; PSBG1; PSGGA
Study 28183547 — Predictive Biomarker (PRD): PSG2 mRNA
Genes: PSG2; PSBG2
Study 28183547 — Predictive Biomarker (PRD): PSG3 mRNA
Genes: PSG3
Study 2845349 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 31675124 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 31675124 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study 31675124 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 6467800 — Surrogate Endpoint (SUR): Blood pressure
Study 27052122 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 22415232 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 25521275 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 19885944 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 19885944 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 8923850 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3888229 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3888229 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16317014 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 14528069 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31170926 — Surrogate Endpoint (SUR): Blood pressure
Study 19488607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19488607 — Surrogate Endpoint (SUR): Blood pressure
Study 15832031 — Predictive Biomarker (PRD): SLBP mRNA
Genes: SLBP; HBP
Study 6351148 — Surrogate Endpoint (SUR): Blood pressure
Study 25918755 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1500686 — Monitoring Biomarker (MOI): HBV DNA
Study 30536163 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 9054246 — Surrogate Endpoint (SUR): Blood pressure
Study 15545877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9450166 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 9450166 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29322434 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23141812 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 23141812 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 2140489 — Surrogate Endpoint (SUR): Blood pressure
Study 2140489 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17023769 — Surrogate Endpoint (SUR): Blood pressure
Study 22535754 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22535754 — Predictive Biomarker (PRD): TNFRSF1A
Genes: TNF-R; TNFAR; TNFR60; TNF-R-I; CD120a; TNF-R55
Study 22535754 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 22535754 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 14745756 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 11756577 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 27317093 — Surrogate Endpoint (SUR): Serum uric acid
Study 10952840 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10952840 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9062836 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27450552 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27450552 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27450552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10674617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10674617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6382172 — Surrogate Endpoint (SUR): Blood pressure
Study 19121921 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19121921 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28566194 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28566194 — Surrogate Endpoint (SUR): Blood pressure
Study 26202097 — Surrogate Endpoint (SUR): Blood pressure
Study 11918129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11918129 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2503295 — Surrogate Endpoint (SUR): Blood pressure
Study 31290017 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 31290017 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 23793133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23793133 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23793133 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23793133 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23793133 — Surrogate Endpoint (SUR): Serum uric acid
Study 15451390 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 15451390 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29580220 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 26846860 — Surrogate Endpoint (SUR): Blood pressure
Study 22441774 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18716735 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10829398 — Surrogate Endpoint (SUR): Blood pressure
Study 8800586 — Surrogate Endpoint (SUR): Blood pressure
Study 30610038 — Predictive Biomarker (PRD): Microsatellite instability
Study 22102090 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 22102090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18815843 — Surrogate Endpoint (SUR): Blood pressure
Study 15902994 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10505693 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1752019 — Surrogate Endpoint (SUR): Blood pressure
Study 23904472 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22484799 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22484799 — Surrogate Endpoint (SUR): Bone mineral density
Study 15821654 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 8471416 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 8471416 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31448793 — Surrogate Endpoint (SUR): Blood pressure
Study 26861608 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 16164886 — Surrogate Endpoint (SUR): Blood pressure
Study 28109057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25643050 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 17600607 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 17600607 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 12004990 — Predictive Biomarker (PRD): KCNQ1 mRNA
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study 7788955 — Surrogate Endpoint (SUR): Blood pressure
Study 29158664 — Surrogate Endpoint (SUR): Blood pressure
Study 19465142 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9460336 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL