TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04640168 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03385070 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01088789 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00207389 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01601483 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04248270 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00300261 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01526070 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04616976 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02069210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00002646 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00758238 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03558906 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03558906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03558906 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study NCT03558906 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00957840 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00957840 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT00957840 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT03209154 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00543972 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT04351022 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT05386784 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00424866 — Safety Biomarker (SAF): Fibroblast growth factor 1
Genes: FGF1
Study NCT01307137 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02147665 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03799692 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01610362 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01937325 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01880086 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00005203 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01185925 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT04071353 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT00261001 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04274244 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00642551 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03299751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03299751 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02594904 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT04051788 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04260009 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03959371 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT03959371 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT00529022 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02080455 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02909491 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02469896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03388346 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02639260 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study NCT00182351 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00542529 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00106522 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03318939 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03318939 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02413385 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02475486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02211352 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02048566 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01813214 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT01813214 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study NCT03726294 — Predictive Biomarker (PRD): BMX mRNA
Genes: BMX
Study NCT03726294 — Predictive Biomarker (PRD): HDAC8 mRNA
Genes: HDAC8; HDACL1; CDA07
Study NCT01735136 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01390181 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT01390181 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study NCT01329809 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02792452 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04953039 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01721135 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02635022 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01969318 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01615250 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03482297 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00519961 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02685670 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study NCT02685670 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT02685670 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04548414 — Safety Biomarker (SAF): MTHFR
Study NCT00485160 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04174547 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study NCT00827801 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02964494 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study NCT03590158 — Predictive Biomarker (PRD): TERF1 mRNA
Genes: TERF1; PIN2; TRBF1; TRF; TRF1
Study NCT03344692 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT03406260 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03976687 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study NCT04376853 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03834987 — Predictive Biomarker (PRD): NGLY1 mRNA
Genes: NGLY1; PNG1
Study NCT01847118 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04175002 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01578109 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01790126 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01790126 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT04251130 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02977208 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study NCT03784651 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03784651 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04322942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04322942 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT04322942 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01103635 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT01103635 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study NCT02301650 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01009203 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01009203 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02039791 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02039791 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03423823 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03423823 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02853721 — Surrogate Endpoint (SUR): Serum calcium
Study NCT01966458 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01133912 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01222637 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT05291000 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04039087 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT03267277 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT00196872 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT03204006 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03227679 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study NCT03327493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01975428 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03008824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03082703 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04235036 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04235036 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00606775 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT02743819 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02743819 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT01187524 — Predictive Biomarker (PRD): FMR1 mRNA
Genes: FMR1
Study NCT02529124 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00745238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00745238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00454220 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00402558 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT03783546 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03316469 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00429936 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00931333 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01344746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01398280 — Predictive Biomarker (PRD): KLK5 mRNA
Genes: KLK5; SCTE; UNQ570/PRO1132
Study NCT03154762 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00409968 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT01329562 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT03352544 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02413749 — Predictive Biomarker (PRD): TRAF3 mRNA
Genes: TRAF3; CAP-1; CRAF1; TRAFAMN
Study NCT02413749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04445181 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00052754 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01760967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01760967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01760967 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00984035 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT01475552 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT01392144 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02216487 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02216487 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00924820 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00924820 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00375219 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00375219 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03606837 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03474016 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02330783 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01739153 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03395470 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT01987570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01306188 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01306188 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01469832 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT00976274 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03337308 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02827630 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04343508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT06618469 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT06618469 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03478150 — Surrogate Endpoint (SUR): Bacterial count
Study NCT03173924 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02712346 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT00846339 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT00300781 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00300781 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00009841 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02781272 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study NCT01774851 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01758263 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00726921 — Predictive Biomarker (PRD): DSE mRNA
Genes: DSE; SART2
Study NCT04432714 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT00065325 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00984425 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00984425 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00984425 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00984425 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00482404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02825875 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02042573 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT02042573 — Predictive Biomarker (PRD): DUSP1 mRNA
Genes: DUSP1; CL100; MKP1; PTPN10; VH1
Study NCT02827357 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01023256 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04930224 — Predictive Biomarker (PRD): GPER1 mRNA
Genes: GPER1; CEPR; CMKRL2; DRY12; GPER; GPR30
Study NCT02741583 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02838147 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03694561 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT01847521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03692767 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT00640016 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT00640016 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study NCT02885090 — Predictive Biomarker (PRD): MECP2 mRNA
Genes: MECP2
Study NCT02885090 — Predictive Biomarker (PRD): Cyclin-dependent kinase-like 5
Genes: CDKL5; STK9
Study NCT02885090 — Predictive Biomarker (PRD): FOXG1 mRNA
Genes: FOXG1; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; FOXG1A; FOXG1B; FOXG1C
Study NCT01280006 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04145531 — Surrogate Endpoint (SUR): Serum asparaginase
Study NCT03428672 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00489229 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04128059 — Surrogate Endpoint (SUR): Neutralizing antibody response
Study NCT04128059 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00484042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00484042 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT05800197 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05800197 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03201068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02481401 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00447031 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01065376 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01065376 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04209465 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04209465 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04209465 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01839500 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00261846 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study NCT00261846 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00261846 — Surrogate Endpoint (SUR): Hematologic response
Study NCT02311998 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT00809211 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03882905 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03882905 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01831297 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02406079 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02343445 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00628251 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00628251 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02234596 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02234596 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04894552 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study NCT03638648 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03638648 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03638648 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03638648 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04516291 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04516291 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study NCT02821468 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT02646748 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT02646748 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01067339 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT00006071 — Surrogate Endpoint (SUR): Blood pressure