TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26417057 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26417057 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 26417057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24614012 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12452403 — Surrogate Endpoint (SUR): Blood pressure
Study 23043951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 1299590 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1299590 — Surrogate Endpoint (SUR): Blood pressure
Study 27156934 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27156934 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29336389 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15815753 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30954486 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30954486 — Predictive Biomarker (PRD): KLF2 mRNA
Genes: KLF2; LKLF
Study 30954486 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24955290 — Surrogate Endpoint (SUR): Blood pressure
Study 20168107 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 7863827 — Surrogate Endpoint (SUR): Bone mineral density
Study 23793032 — Surrogate Endpoint (SUR): Blood pressure
Study 11703440 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3429683 — Surrogate Endpoint (SUR): Blood pressure
Study 21622980 — Surrogate Endpoint (SUR): Blood pressure
Study 21622980 — Surrogate Endpoint (SUR): Serum creatinine
Study 16880100 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26135803 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 26135803 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 14630680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25444793 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 25444793 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 11194527 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11194527 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 11194527 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23884439 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 23884439 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 29165732 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19531608 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 10955790 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10955790 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 10955790 — Predictive Biomarker (PRD): CDKN1A mRNA
Genes: CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1
Study 10955790 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21887727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20134178 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 20134178 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12225329 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 9799034 — Surrogate Endpoint (SUR): Blood pressure
Study 28327172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23410231 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28652127 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24458541 — Surrogate Endpoint (SUR): Blood pressure
Study 22362844 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15644045 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27883159 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 16222899 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16222899 — Surrogate Endpoint (SUR): Blood pressure
Study 9797077 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 9797077 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 9797077 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 25736975 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 16798209 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8939177 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8939177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8939177 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8939177 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 16164922 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16164922 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 23485996 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23485996 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15327428 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 11466099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11466099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31383718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24080439 — Surrogate Endpoint (SUR): Blood pressure
Study 16081469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2283674 — Surrogate Endpoint (SUR): Blood pressure
Study 30955220 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 30955220 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 25528262 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 2567114 — Surrogate Endpoint (SUR): Blood pressure
Study 25244700 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23715820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23715820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10719404 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10719404 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9013266 — Surrogate Endpoint (SUR): Blood pressure
Study 22753904 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20444847 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 29754666 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 26176643 — Surrogate Endpoint (SUR): Blood pressure
Study 24762158 — Predictive Biomarker (PRD): SLMAP mRNA
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 17057049 — Surrogate Endpoint (SUR): Blood pressure
Study 17057049 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12635025 — Surrogate Endpoint (SUR): Blood pressure
Study 9166162 — Surrogate Endpoint (SUR): Bone mineral density
Study 22673017 — Surrogate Endpoint (SUR): Blood pressure
Study 2141110 — Surrogate Endpoint (SUR): Serum creatinine
Study 24534317 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20376076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3961029 — Surrogate Endpoint (SUR): Blood pressure
Study 31112543 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20705561 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18192851 — Surrogate Endpoint (SUR): Blood pressure
Study 27000071 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 26690313 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25155931 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 23121377 — Surrogate Endpoint (SUR): Total kidney volume
Study 23121377 — Surrogate Endpoint (SUR): Serum creatinine
Study 31655508 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24121184 — Monitoring Biomarker (MOI): Procalcitonin
Study 14517707 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 14517707 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 24637411 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 24637411 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31070702 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31694631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15231013 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9733025 — Surrogate Endpoint (SUR): Serum uric acid
Study 8289481 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3188048 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25404086 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 25404086 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 17307447 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11274935 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11274935 — Surrogate Endpoint (SUR): Blood pressure
Study 11274935 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9844956 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 22990513 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 30489151 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 25273912 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22850442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22850442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30628526 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28866370 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 25739842 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 18077945 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18077945 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18077945 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18077945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1833165 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1833165 — Surrogate Endpoint (SUR): Blood pressure
Study 17638305 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 11934348 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 25001269 — Surrogate Endpoint (SUR): Blood pressure
Study 8911861 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29397850 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 19887462 — Surrogate Endpoint (SUR): Blood pressure
Study 17699009 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 11999090 — Surrogate Endpoint (SUR): Blood pressure
Study 1692926 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1692926 — Surrogate Endpoint (SUR): Blood pressure
Study 31406538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26188833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26188833 — Surrogate Endpoint (SUR): Blood pressure
Study 20804269 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 18978165 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10053176 — Surrogate Endpoint (SUR): Blood pressure
Study 26494529 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15680718 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31272285 — Predictive Biomarker (PRD): FGF5 mRNA
Genes: FGF5
Study 31272285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31272285 — Predictive Biomarker (PRD): miR-145
Genes: MIR145
Study 31272285 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31272285 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 26782835 — Surrogate Endpoint (SUR): Blood pressure
Study 24421302 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 2684174 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 786689 — Surrogate Endpoint (SUR): Blood pressure
Study 26072017 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9425400 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 25588130 — Surrogate Endpoint (SUR): Blood pressure
Study 9252517 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9252517 — Safety Biomarker (SAF): CCKAR
Study 30871496 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 20953593 — Surrogate Endpoint (SUR): Serum calcium
Study 10807190 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8794812 — Surrogate Endpoint (SUR): Blood pressure
Study 1536438 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 1536438 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10553163 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10553163 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26474174 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19100061 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 15790932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2054278 — Surrogate Endpoint (SUR): Blood pressure
Study 12208796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31432689 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18821872 — Surrogate Endpoint (SUR): Blood pressure
Study 25613747 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22447467 — Surrogate Endpoint (SUR): Blood pressure
Study 22447467 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19000959 — Surrogate Endpoint (SUR): Blood pressure
Study 14587237 — Predictive Biomarker (PRD): Microsatellite instability
Study 30824408 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 26847219 — Surrogate Endpoint (SUR): Blood pressure
Study 9150971 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3006414 — Surrogate Endpoint (SUR): Blood pressure
Study 28029752 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17258926 — Surrogate Endpoint (SUR): Blood pressure
Study 9814473 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2468927 — Surrogate Endpoint (SUR): Blood pressure
Study 25868059 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22509642 — Safety Biomarker (SAF): Hyaluronic acid
Study 15365066 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23547079 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 2024911 — Surrogate Endpoint (SUR): Blood pressure
Study 6421007 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29924642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29924642 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29924642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29924642 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 29924642 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29924642 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22158330 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 30563042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30563042 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30563042 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 30563042 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 30563042 — Safety Biomarker (SAF): Reactive oxygen species
Study 25017345 — Surrogate Endpoint (SUR): Blood pressure
Study 10193676 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7479625 — Surrogate Endpoint (SUR): Blood pressure
Study 30475762 — Predictive Biomarker (PRD): MYB mRNA
Genes: MYB
Study 8935302 — Surrogate Endpoint (SUR): Blood pressure
Study 26902403 — Predictive Biomarker (PRD): CTSG mRNA
Genes: CTSG
Study 26902403 — Predictive Biomarker (PRD): TACR1 mRNA
Genes: TACR1; NK1R; TAC1R
Study 26902403 — Predictive Biomarker (PRD): HSPG2 mRNA
Genes: HSPG2
Study 26902403 — Predictive Biomarker (PRD): HYAL1 mRNA
Genes: HYAL1; LUCA1
Study 26902403 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 26902403 — Surrogate Endpoint (SUR): Bone mineral density
Study 19663089 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 15801939 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18320208 — Safety Biomarker (SAF): Reactive oxygen species
Study 19996072 — Surrogate Endpoint (SUR): Blood pressure
Study 18036291 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 18036291 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 11453909 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 17952446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17952446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22445187 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15892437 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21820871 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21820871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21820871 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11751803 — Surrogate Endpoint (SUR): Blood pressure
Study 152681 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 26541328 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16758046 — Surrogate Endpoint (SUR): Serum creatinine
Study 9388047 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9388047 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9388047 — Surrogate Endpoint (SUR): Blood pressure
Study 7955922 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7955922 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21696537 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 11716192 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9173971 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 27302672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18334918 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 10801253 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30843231 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26656679 — Surrogate Endpoint (SUR): Blood pressure
Study 12087350 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12087350 — Surrogate Endpoint (SUR): Blood pressure
Study 12087350 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 31339827 — Predictive Biomarker (PRD): Hormone receptor
Study 18942777 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 26259133 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 23447647 — Surrogate Endpoint (SUR): Blood pressure
Study 26544615 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 26544615 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16549463 — Surrogate Endpoint (SUR): Blood pressure
Study 29862568 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24378099 — Predictive Biomarker (PRD): Hormone receptor
Study 9467472 — Surrogate Endpoint (SUR): Blood pressure
Study 25327949 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 6105713 — Surrogate Endpoint (SUR): Blood pressure
Study 28231265 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 24225216 — Monitoring Biomarker (MOI): Procalcitonin
Study 24363547 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21910334 — Predictive Biomarker (PRD): ACSM3 mRNA
Genes: ACSM3; SAH
Study 1361240 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30544237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30544237 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30544237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7654482 — Surrogate Endpoint (SUR): Blood pressure