TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25418492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25418492 — Surrogate Endpoint (SUR): Blood pressure
Study 23687222 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23687222 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 20502415 — Surrogate Endpoint (SUR): Blood pressure
Study 18426826 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12865039 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25171042 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7315774 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7315774 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29633367 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 27897610 — Surrogate Endpoint (SUR): Blood pressure
Study 23989533 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11802037 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11802037 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 11802037 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11802037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11802037 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10391281 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 9351353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26233481 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21527567 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 18815937 — Surrogate Endpoint (SUR): Blood pressure
Study 3536231 — Surrogate Endpoint (SUR): Serum creatinine
Study 16735449 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8140941 — Surrogate Endpoint (SUR): Serum creatinine
Study 29537903 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 29537903 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29537903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24094907 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19234845 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19234845 — Surrogate Endpoint (SUR): Blood pressure
Study 17620776 — Safety Biomarker (SAF): Hyaluronic acid
Study 520397 — Surrogate Endpoint (SUR): Blood pressure
Study 21529314 — Surrogate Endpoint (SUR): Blood pressure
Study 18480967 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 17121193 — Surrogate Endpoint (SUR): Blood pressure
Study 25512256 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 29253140 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 11387501 — Surrogate Endpoint (SUR): Blood pressure
Study 10821345 — Surrogate Endpoint (SUR): Blood pressure
Study 1452929 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22152080 — Surrogate Endpoint (SUR): Blood pressure
Study 17494679 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 30991881 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23271615 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 23271615 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 23271615 — Surrogate Endpoint (SUR): Blood pressure
Study 29359279 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28692770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20038957 — Predictive Biomarker (PRD): SULT1C2 mRNA
Genes: SULT1C2; SULT1C1
Study 20038957 — Predictive Biomarker (PRD): CHST3 mRNA
Genes: CHST3
Study 20038957 — Predictive Biomarker (PRD): SPG7 mRNA
Genes: SPG7; CAR; CMAR; PGN
Study 20038957 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20038957 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 20038957 — Predictive Biomarker (PRD): ATP7A mRNA
Genes: ATP7A; MC1; MNK
Study 10745332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30831541 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 30831541 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25368202 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23549824 — Surrogate Endpoint (SUR): Blood pressure
Study 16673249 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16673249 — Predictive Biomarker (PRD): Hormone receptor
Study 9324340 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 18024166 — Surrogate Endpoint (SUR): Blood pressure
Study 8781005 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 26248047 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 19606937 — Surrogate Endpoint (SUR): Blood pressure
Study 4898 — Surrogate Endpoint (SUR): Blood pressure
Study 27830967 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25915168 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 25915168 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25915168 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2478790 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2478790 — Surrogate Endpoint (SUR): Blood pressure
Study 20459012 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15691863 — Surrogate Endpoint (SUR): Blood pressure
Study 12665638 — Surrogate Endpoint (SUR): Bone mineral density
Study 26603110 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 26603110 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24884504 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 2190504 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 12037733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24903467 — Surrogate Endpoint (SUR): Blood pressure
Study 20837942 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 20837942 — Predictive Biomarker (PRD): Hormone receptor
Study 11817501 — Surrogate Endpoint (SUR): Blood pressure
Study 25077418 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 16126118 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16126118 — Surrogate Endpoint (SUR): Blood pressure
Study 10408666 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27937077 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27937077 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21632072 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19497091 — Surrogate Endpoint (SUR): Serum creatinine
Study 11488772 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 9138439 — Surrogate Endpoint (SUR): Blood pressure
Study 10213434 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 29498351 — Surrogate Endpoint (SUR): Blood pressure
Study 26224203 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 26224203 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24625755 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24625755 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 22484031 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23645763 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 23645763 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 23645763 — Predictive Biomarker (PRD): GLIS2 mRNA
Genes: GLIS2; NKL
Study 23645763 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 9475648 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8582538 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 2215098 — Surrogate Endpoint (SUR): Blood pressure
Study 380941 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 30207586 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19153580 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19153580 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9764962 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 23527013 — Predictive Biomarker (PRD): TRIM27 mRNA
Genes: TRIM27; RFP; RNF76
Study 23527013 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 23527013 — Predictive Biomarker (PRD): CETN3 mRNA
Genes: CETN3; CEN3
Study 17440528 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 17440528 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10972368 — Surrogate Endpoint (SUR): Blood pressure
Study 26988798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26988798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26988798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26988798 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23444397 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21253392 — Surrogate Endpoint (SUR): Bone mineral density
Study 12678277 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 12678277 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1397674 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26714287 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 22572418 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 18047921 — Surrogate Endpoint (SUR): Blood pressure
Study 18047921 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18047921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8750365 — Surrogate Endpoint (SUR): Blood pressure
Study 8750365 — Surrogate Endpoint (SUR): Serum sodium
Study 8750365 — Surrogate Endpoint (SUR): Serum calcium
Study 8750365 — Surrogate Endpoint (SUR): Serum potassium
Study 25317545 — Surrogate Endpoint (SUR): Blood pressure
Study 20353028 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 9928755 — Surrogate Endpoint (SUR): Blood pressure
Study 6756418 — Surrogate Endpoint (SUR): Blood pressure
Study 14694168 — Surrogate Endpoint (SUR): Serum creatinine
Study 2656860 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2656860 — Surrogate Endpoint (SUR): Blood pressure
Study 28255731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21498786 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16989902 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 22507791 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 22507791 — Predictive Biomarker (PRD): CES2 mRNA
Genes: CES2; ICE
Study 15967223 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 31907007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28745674 — Predictive Biomarker (PRD): KRIT1 mRNA
Genes: KRIT1; CCM1
Study 28745674 — Predictive Biomarker (PRD): CCM2 mRNA
Genes: CCM2; C7orf22; PP10187
Study 21386706 — Surrogate Endpoint (SUR): Blood pressure
Study 28355317 — Surrogate Endpoint (SUR): Blood pressure
Study 21862934 — Surrogate Endpoint (SUR): Serum creatinine
Study 17320090 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 17320090 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 17320090 — Surrogate Endpoint (SUR): Blood pressure
Study 17320090 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12575392 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 7874375 — Surrogate Endpoint (SUR): Blood pressure
Study 31675993 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 31675993 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22581292 — Surrogate Endpoint (SUR): Bone mineral density
Study 9135733 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 7698130 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12671890 — Surrogate Endpoint (SUR): Serum sodium
Study 30912767 — Predictive Biomarker (PRD): LEF1 mRNA
Genes: LEF1
Study 30912767 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FasL mRNA
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 30912767 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 15700313 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 10844380 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7552520 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17639748 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17639748 — Surrogate Endpoint (SUR): Probing pocket depth
Study 31640977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23675619 — Surrogate Endpoint (SUR): Blood pressure
Study 19526754 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 17338713 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16422810 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 16422810 — Predictive Biomarker (PRD): SEPTIN6 mRNA
Genes: SEPTIN6; KIAA0128; SEP2; SEPT6
Study 16422810 — Predictive Biomarker (PRD): SEPTIN3 mRNA
Genes: SEPTIN3; SEP3; SEPT3
Study 10381294 — Surrogate Endpoint (SUR): Blood pressure
Study 500834 — Surrogate Endpoint (SUR): Serum calcium
Study 28005225 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 2354484 — Surrogate Endpoint (SUR): Blood pressure
Study 27503851 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27503851 — Surrogate Endpoint (SUR): Blood pressure
Study 23009149 — Surrogate Endpoint (SUR): Bone mineral density
Study 21077572 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 11828246 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11828246 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 2310247 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28109295 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28109295 — Surrogate Endpoint (SUR): Blood pressure
Study 11153017 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11153017 — Surrogate Endpoint (SUR): Blood pressure
Study 20852881 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18367379 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9104860 — Surrogate Endpoint (SUR): Blood pressure
Study 2486782 — Surrogate Endpoint (SUR): Blood pressure
Study 23021155 — Surrogate Endpoint (SUR): Blood pressure
Study 22036523 — Safety Biomarker (SAF): Interleukin 1
Study 22036523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22036523 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22036523 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22036523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22036523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16998289 — Surrogate Endpoint (SUR): Serum creatinine
Study 22947545 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 25603432 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 25603432 — Predictive Biomarker (PRD): NEB mRNA
Genes: NEB
Study 19487177 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15152060 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21806572 — Surrogate Endpoint (SUR): Blood pressure
Study 16684279 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16684279 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9224961 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7737957 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 24843061 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24843061 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18052556 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 25867415 — Surrogate Endpoint (SUR): Serum creatinine
Study 11337977 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11337977 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29544472 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 26856220 — Surrogate Endpoint (SUR): Serum creatinine
Study 24694337 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24694337 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24694337 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22319034 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 12037720 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 10404854 — Surrogate Endpoint (SUR): Blood pressure
Study 7672750 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 28079534 — Surrogate Endpoint (SUR): Blood pressure
Study 11059542 — Surrogate Endpoint (SUR): Blood pressure
Study 27398874 — Surrogate Endpoint (SUR): Blood pressure
Study 27398874 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24752908 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 24752908 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20299990 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 9772043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9772043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25465941 — Surrogate Endpoint (SUR): Blood pressure
Study 11205461 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15264116 — Monitoring Biomarker (MOI): HBV DNA
Study 12271297 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21638048 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21638048 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21638048 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21638048 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16881093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8735490 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 28927706 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 15351240 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24076063 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24076063 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21242072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20205984 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 22848074 — Surrogate Endpoint (SUR): Blood pressure
Study 19167925 — Surrogate Endpoint (SUR): Bone mineral density
Study 17391951 — Predictive Biomarker (PRD): CCN2 mRNA
Genes: CCN2; CTGF; HCS24; IGFBP8
Study 17391951 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11249725 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 9218922 — Surrogate Endpoint (SUR): Blood pressure
Study 20375028 — Surrogate Endpoint (SUR): Blood pressure
Study 20375028 — Surrogate Endpoint (SUR): Serum creatinine
Study 9717594 — Surrogate Endpoint (SUR): Blood pressure
Study 24706006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23220209 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16699359 — Surrogate Endpoint (SUR): Blood pressure
Study 9085124 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24655702 — Surrogate Endpoint (SUR): Blood pressure
Study 12740743 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12740743 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15143453 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15143453 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 11748098 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28454800 — Surrogate Endpoint (SUR): Blood pressure
Study 26054139 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26054139 — Surrogate Endpoint (SUR): Blood pressure
Study 26054139 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26054139 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20820870 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27631254 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 22317756 — Surrogate Endpoint (SUR): Blood pressure
Study 22726401 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30149148 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15017898 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11343668 — Surrogate Endpoint (SUR): Blood pressure
Study 26352805 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31272205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21091548 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21310741 — Safety Biomarker (SAF): Cystatin C
Genes: CST3