TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20032478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20032478 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11552015 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3185464 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 27838474 — Surrogate Endpoint (SUR): Blood pressure
Study 3141293 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 2082718 — Surrogate Endpoint (SUR): Blood pressure
Study 10094751 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10094751 — Surrogate Endpoint (SUR): Blood pressure
Study 21508180 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 28944901 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 28944901 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 11420324 — Surrogate Endpoint (SUR): Blood pressure
Study 10322818 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8215734 — Surrogate Endpoint (SUR): Serum potassium
Study 8215734 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24186676 — Surrogate Endpoint (SUR): Bone mineral density
Study 23039824 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 23039824 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 23039824 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23039824 — Surrogate Endpoint (SUR): Blood pressure
Study 22338468 — Monitoring Biomarker (MOI): Procalcitonin
Study 19444516 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 14745141 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 3297471 — Surrogate Endpoint (SUR): Blood pressure
Study 30625094 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 25710287 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 18394495 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 15292740 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 11315234 — Surrogate Endpoint (SUR): Bone mineral density
Study 31331265 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 28380313 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28380313 — Predictive Biomarker (PRD): Hormone receptor
Study 9505772 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22537244 — Surrogate Endpoint (SUR): Blood pressure
Study 15751775 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30935524 — Surrogate Endpoint (SUR): Blood pressure
Study 27543374 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 25070319 — Surrogate Endpoint (SUR): Serum calcium
Study 31357887 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31357887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24692082 — Predictive Biomarker (PRD): Hormone receptor
Study 20175427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10822073 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10822073 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10822073 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10822073 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15610250 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15610250 — Surrogate Endpoint (SUR): Serum creatinine
Study 11939936 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 24340926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18710817 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 24225450 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24225450 — Surrogate Endpoint (SUR): Serum triglycerides
Study 24225450 — Surrogate Endpoint (SUR): Serum uric acid
Study 22101910 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15983958 — Surrogate Endpoint (SUR): Serum calcium
Study 14763035 — Surrogate Endpoint (SUR): Blood pressure
Study 14763035 — Surrogate Endpoint (SUR): Serum creatinine
Study 20581660 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 20581660 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 20581660 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 20581660 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17295794 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 17295794 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17295794 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 17295794 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 12602413 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 8746877 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7094200 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 20872194 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9426077 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 29280940 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29280940 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23887656 — Surrogate Endpoint (SUR): Blood pressure
Study 19878195 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 8881668 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 27088635 — Surrogate Endpoint (SUR): Blood pressure
Study 25295737 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25295737 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12753317 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12753317 — Surrogate Endpoint (SUR): Bone mineral density
Study 12753317 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12753317 — Surrogate Endpoint (SUR): Serum triglycerides
Study 1900575 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 6823860 — Surrogate Endpoint (SUR): Blood pressure
Study 29746446 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28514618 — Surrogate Endpoint (SUR): Bone mineral density
Study 17000789 — Surrogate Endpoint (SUR): Blood pressure
Study 17000789 — Surrogate Endpoint (SUR): Serum creatinine
Study 8993489 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24739766 — Predictive Biomarker (PRD): CASQ1 mRNA
Genes: CASQ1; CASQ
Study 31583738 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 27793396 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11144995 — Safety Biomarker (SAF): RFC1
Genes: A1; PO-GA; RFC140; MHCBFB
Study 30899994 — Surrogate Endpoint (SUR): Bone mineral density
Study 19841760 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 1498073 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 10023125 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 31646460 — Surrogate Endpoint (SUR): Serum creatinine
Study 29447379 — Safety Biomarker (SAF): Reactive oxygen species
Study 25601896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20544489 — Surrogate Endpoint (SUR): Blood pressure
Study 20544489 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17953631 — Safety Biomarker (SAF): Reactive oxygen species
Study 12555375 — Surrogate Endpoint (SUR): Blood pressure
Study 23231777 — Surrogate Endpoint (SUR): Blood pressure
Study 2121150 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2121150 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19433812 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11769816 — Surrogate Endpoint (SUR): Blood pressure
Study 3076140 — Surrogate Endpoint (SUR): Blood pressure
Study 27997282 — Surrogate Endpoint (SUR): Blood pressure
Study 27997282 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23669822 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 18042591 — Surrogate Endpoint (SUR): Serum creatinine
Study 9386902 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24564262 — Surrogate Endpoint (SUR): Blood pressure
Study 22398072 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 12461494 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 1696795 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31772506 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 11763107 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11763107 — Surrogate Endpoint (SUR): Blood pressure
Study 31415827 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 25023433 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 21786187 — Surrogate Endpoint (SUR): Blood pressure
Study 8466895 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26610430 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 25445074 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17323071 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29529222 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23985706 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23985706 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23985706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23985706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28724365 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 28724365 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 18332063 — Surrogate Endpoint (SUR): Blood pressure
Study 21342915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15094401 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9749163 — Surrogate Endpoint (SUR): Blood pressure
Study 28314838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28314838 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17636399 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27180107 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 24595629 — Surrogate Endpoint (SUR): Blood pressure
Study 30777526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30777526 — Surrogate Endpoint (SUR): Serum creatinine
Study 30777526 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30777526 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22337244 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21979989 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21979989 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 21979989 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21979989 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21979989 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16581422 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 6669632 — Surrogate Endpoint (SUR): Blood pressure
Study 28645934 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 28645934 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24002511 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24002511 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24002511 — Predictive Biomarker (PRD): Hormone receptor
Study 7827349 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 26578409 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21123462 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16782488 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8131529 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2683789 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2683789 — Surrogate Endpoint (SUR): Blood pressure
Study 2683789 — Surrogate Endpoint (SUR): Serum creatinine
Study 28109128 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 798576 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 30918121 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 16984699 — Surrogate Endpoint (SUR): Blood pressure
Study 7752180 — Surrogate Endpoint (SUR): Blood pressure
Study 28864689 — Surrogate Endpoint (SUR): Blood pressure
Study 17500020 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17500020 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15012690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11058789 — Predictive Biomarker (PRD): A2M mRNA
Genes: A2M; CPAMD5; FWP007
Study 11058789 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 3578970 — Surrogate Endpoint (SUR): Blood pressure
Study 27874837 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24553973 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20448541 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31222771 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19168461 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 26700275 — Surrogate Endpoint (SUR): Blood pressure
Study 17466972 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 17466972 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9576406 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9576406 — Surrogate Endpoint (SUR): Blood pressure
Study 9576406 — Surrogate Endpoint (SUR): Serum creatinine
Study 7935702 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1592715 — Predictive Biomarker (PRD): OGT mRNA
Genes: OGT
Study 29636247 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26260216 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 21651447 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10559769 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 7576669 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2156277 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21762225 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 21762225 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11230791 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11230791 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21079818 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21079818 — Surrogate Endpoint (SUR): Blood pressure
Study 21079818 — Surrogate Endpoint (SUR): Serum creatinine
Study 10340790 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 10340790 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 1701714 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31800000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31800000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28400487 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24165392 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 15089820 — Surrogate Endpoint (SUR): Blood pressure
Study 9104896 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29660351 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31986290 — Surrogate Endpoint (SUR): Blood pressure
Study 25193793 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8806006 — Surrogate Endpoint (SUR): Bone mineral density
Study 8806006 — Surrogate Endpoint (SUR): Serum calcium
Study 22440372 — Surrogate Endpoint (SUR): Blood pressure
Study 16376748 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 8719263 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8719263 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 28224720 — Surrogate Endpoint (SUR): Blood pressure
Study 22782640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24368354 — Surrogate Endpoint (SUR): Blood pressure
Study 27302626 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27302626 — Surrogate Endpoint (SUR): Blood pressure
Study 11810082 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30138014 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 11668378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30064455 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 30064455 — Safety Biomarker (SAF): Hyaluronic acid
Study 21349184 — Surrogate Endpoint (SUR): Blood pressure
Study 18469276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18469276 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25935875 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 25935875 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 25935875 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 25935875 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25935875 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 18388897 — Surrogate Endpoint (SUR): Blood pressure
Study 16864174 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 16864174 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12356187 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 12356187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7016781 — Surrogate Endpoint (SUR): Blood pressure
Study 2523493 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 25495748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21131132 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 21131132 — Predictive Biomarker (PRD): ADGRE5 mRNA
Genes: ADGRE5; CD97
Study 15259389 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15016643 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 15016643 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9439537 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22188544 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 20159820 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7555486 — Surrogate Endpoint (SUR): Blood pressure
Study 25943532 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 14615732 — Surrogate Endpoint (SUR): Serum sodium
Study 7799046 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21239636 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21239636 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 21239636 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 7964947 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10870746 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 26830098 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 26830098 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 26830098 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26830098 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26830098 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26830098 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 24274379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24274379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24274379 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24274379 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24274379 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22227851 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12665916 — Monitoring Biomarker (MOI): HBV DNA
Study 8074071 — Surrogate Endpoint (SUR): Serum calcium
Study 21482217 — Surrogate Endpoint (SUR): Blood pressure
Study 3691557 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 27522247 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25479285 — Surrogate Endpoint (SUR): Blood pressure
Study 20028815 — Monitoring Biomarker (MOI): HBV DNA
Study 18360262 — Surrogate Endpoint (SUR): Serum creatinine
Study 28658431 — Surrogate Endpoint (SUR): Blood pressure
Study 26071836 — Surrogate Endpoint (SUR): Blood pressure
Study 19729908 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 19729908 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14760893 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4