TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12927226 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12927226 — Surrogate Endpoint (SUR): Blood pressure
Study 31825895 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27921992 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 25102685 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 9639218 — Surrogate Endpoint (SUR): Blood pressure
Study 21292168 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 17186295 — Predictive Biomarker (PRD): PDK4 mRNA
Genes: PDK4; PDHK4
Study 17186295 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 15248230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8611664 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 19468742 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 7988249 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 21445680 — Surrogate Endpoint (SUR): Blood pressure
Study 17249520 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11808059 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 23601499 — Surrogate Endpoint (SUR): Serum sodium
Study 23601499 — Surrogate Endpoint (SUR): Serum creatinine
Study 20625264 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20625264 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16325777 — Predictive Biomarker (PRD): AQP7 mRNA
Genes: AQP7; AQP7L; AQP9
Study 20495438 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15985573 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 15985573 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 8902989 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 6275987 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 27217703 — Predictive Biomarker (PRD): TBC1D17 mRNA
Genes: TBC1D17
Study 27217703 — Predictive Biomarker (PRD): CCL3L3 mRNA
Genes: CCL3L1; D17S1718; G0S19-2; SCYA3L1; CCL3L3
Study 27217703 — Predictive Biomarker (PRD): CYFIP2 mRNA
Genes: CYFIP2; KIAA1168; PIR121
Study 27217703 — Predictive Biomarker (PRD): CD6 mRNA
Genes: CD6
Study 27217703 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study 27217703 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 19114869 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30242234 — Predictive Biomarker (PRD): PCSK7 mRNA
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 19209987 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 29176684 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 23945051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21937420 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12702550 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9952363 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7294770 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 7294770 — Surrogate Endpoint (SUR): Serum creatinine
Study 21668975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30885256 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30885256 — Safety Biomarker (SAF): BDNF
Study 23493898 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 19692680 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15566590 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11130223 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15924982 — Surrogate Endpoint (SUR): Blood pressure
Study 12486284 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 8670319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24836312 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22614874 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 22614874 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19739124 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10704165 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 10704165 — Surrogate Endpoint (SUR): Blood pressure
Study 12743150 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15730366 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 27523814 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 23869585 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8983613 — Surrogate Endpoint (SUR): Serum creatinine
Study 27902622 — Surrogate Endpoint (SUR): Blood pressure
Study 31356878 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 20472865 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 20472865 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 15886380 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 15886380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8704419 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 2360920 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 2360920 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30917842 — Surrogate Endpoint (SUR): Pathological complete response
Study 29402332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24203065 — Predictive Biomarker (PRD): MYOD1 mRNA
Genes: MYOD1; BHLHC1; MYF3; MYOD
Study 24203065 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Growth/differentiation factor 8
Genes: MSTN; GDF8
Study 24203065 — Predictive Biomarker (PRD): FST mRNA
Genes: FST
Study 24203065 — Predictive Biomarker (PRD): FOXO3 mRNA
Genes: FOXO3; FKHRL1; FOXO3A
Study 24203065 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 16087950 — Predictive Biomarker (PRD): Hormone receptor
Study 1449389 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 2869574 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2869574 — Surrogate Endpoint (SUR): Blood pressure
Study 23800880 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 6399891 — Surrogate Endpoint (SUR): Blood pressure
Study 14708444 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14708444 — Surrogate Endpoint (SUR): Blood pressure
Study 8145430 — Surrogate Endpoint (SUR): Blood pressure
Study 27758064 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27758064 — Surrogate Endpoint (SUR): Blood pressure
Study 22209967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22209967 — Surrogate Endpoint (SUR): Blood pressure
Study 2790538 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12928047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11192361 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25604111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25604111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9152566 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9152566 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 29353543 — Safety Biomarker (SAF): BDNF
Study 29353543 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17851566 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 17851566 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 8934367 — Surrogate Endpoint (SUR): Blood pressure
Study 10586091 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 10586091 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26449338 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 29913528 — Surrogate Endpoint (SUR): Blood pressure
Study 27074340 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22385586 — Surrogate Endpoint (SUR): Blood pressure
Study 17198742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 2609138 — Safety Biomarker (SAF): Vitamin K-dependent protein C
Genes: PROC
Study 25868877 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 23991206 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23991206 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 23991206 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study 19248193 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19248193 — Surrogate Endpoint (SUR): Blood pressure
Study 9543148 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 12088943 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9488197 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30721948 — Predictive Biomarker (PRD): Liver iron
Study 16362784 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12528093 — Surrogate Endpoint (SUR): Blood pressure
Study 19333944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17961421 — Surrogate Endpoint (SUR): Blood pressure
Study 8092235 — Surrogate Endpoint (SUR): Blood pressure
Study 27878780 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 29652567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29652567 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 29652567 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29652567 — Safety Biomarker (SAF): Reactive oxygen species
Study 22124575 — Surrogate Endpoint (SUR): Bone mineral density
Study 15774791 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 11940756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2351367 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7014042 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 12352146 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8719015 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11264555 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27025337 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24824310 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 20181679 — Surrogate Endpoint (SUR): Blood pressure
Study 9860397 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2527546 — Surrogate Endpoint (SUR): Blood pressure
Study 3320381 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24297090 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 2809191 — Surrogate Endpoint (SUR): Blood pressure
Study 6996815 — Surrogate Endpoint (SUR): Blood pressure
Study 28330721 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 22580858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19013259 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 7736484 — Surrogate Endpoint (SUR): Blood pressure
Study 2927990 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2927990 — Surrogate Endpoint (SUR): Blood pressure
Study 2927990 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2927990 — Surrogate Endpoint (SUR): Serum potassium
Study 31825704 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 17405298 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15333852 — Surrogate Endpoint (SUR): Bone mineral density
Study 21389303 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 17909718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17909718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17909718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17909718 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 24258313 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 24258313 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24258313 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 18202091 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 14641610 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10377504 — Surrogate Endpoint (SUR): Bone mineral density
Study 30646142 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 24715706 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 15982798 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30865794 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7545214 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2523644 — Surrogate Endpoint (SUR): Blood pressure
Study 506802 — Surrogate Endpoint (SUR): Blood pressure
Study 19704401 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 11583884 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16974115 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 10998460 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10998460 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 1431312 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 1431312 — Safety Biomarker (SAF): Interleukin 1
Study 31308274 — Surrogate Endpoint (SUR): Bacterial count
Study 26659366 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 24661196 — Safety Biomarker (SAF): Reactive oxygen species
Study 17921396 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16047057 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28096758 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28096758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28096758 — Surrogate Endpoint (SUR): Blood pressure
Study 26086833 — Surrogate Endpoint (SUR): Serum creatinine
Study 22107734 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15333855 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29251282 — Safety Biomarker (SAF): DRD2
Study 28704263 — Surrogate Endpoint (SUR): Blood pressure
Study 18982918 — Surrogate Endpoint (SUR): Bone mineral density
Study 12887480 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10100557 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1746424 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7048879 — Surrogate Endpoint (SUR): Blood pressure
Study 10642289 — Surrogate Endpoint (SUR): Blood pressure
Study 8446137 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8446137 — Surrogate Endpoint (SUR): Blood pressure
Study 29488276 — Predictive Biomarker (PRD): GLP1R mRNA
Genes: GLP1R
Study 29488276 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 8862260 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1299501 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 27106721 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 18418961 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18418961 — Monitoring Biomarker (MOI): HBV DNA
Study 6596055 — Surrogate Endpoint (SUR): Blood pressure
Study 27052635 — Surrogate Endpoint (SUR): Bone mineral density
Study 37094 — Surrogate Endpoint (SUR): Blood pressure
Study 28244706 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19273709 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 19273709 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 19273709 — Predictive Biomarker (PRD): Microsatellite instability
Study 15054036 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 15054036 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11964529 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7637045 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 2515399 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28319871 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19335078 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 15306157 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 29506034 — Safety Biomarker (SAF): Hyaluronic acid
Study 22578899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22578899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17564719 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11802924 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2551242 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 26304464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21270185 — Surrogate Endpoint (SUR): Serum creatinine
Study 19922256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9819168 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 11589838 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30256548 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 11923558 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 2523769 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 28426885 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 16968715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10753829 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 27341795 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 12131602 — Predictive Biomarker (PRD): ZFYVE9 mRNA
Genes: ZFYVE9; MADHIP; SARA; SMADIP
Study 18259972 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16806442 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 9165581 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23276888 — Surrogate Endpoint (SUR): Bone mineral density
Study 16868708 — Safety Biomarker (SAF): Reactive oxygen species
Study 9316529 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 3536530 — Surrogate Endpoint (SUR): Blood pressure
Study 30832692 — Predictive Biomarker (PRD): RNF128 mRNA
Genes: RNF128
Study 30832692 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 30832692 — Predictive Biomarker (PRD): CTTN mRNA
Genes: CTTN; EMS1
Study 24818523 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 23911273 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 23911273 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 22235508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22235508 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9141585 — Surrogate Endpoint (SUR): Blood pressure
Study 8263640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26311415 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 2552717 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2552717 — Surrogate Endpoint (SUR): Blood pressure
Study 21964491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28229278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21641345 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 10930154 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15830647 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 31362189 — Surrogate Endpoint (SUR): Blood pressure
Study 12859533 — Surrogate Endpoint (SUR): Blood pressure
Study 12859533 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31425585 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31425585 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 25015021 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 25015021 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 25015021 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 8959891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8959891 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 8959891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8959891 — Safety Biomarker (SAF): Reactive oxygen species
Study 2991689 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 24885388 — Surrogate Endpoint (SUR): Blood pressure
Study 15218043 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 15218043 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 15218043 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 15218043 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 15218043 — Safety Biomarker (SAF): Interleukin 1
Study 23737646 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20649936 — Surrogate Endpoint (SUR): Blood pressure