TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04273932 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT00397592 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00397592 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01547832 — Predictive Biomarker (PRD): PRKN mRNA
Genes: PRKN; PARK2
Study NCT01928654 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT01928654 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03793075 — Safety Biomarker (SAF): Interleukin 1
Study NCT03793075 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03263091 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study NCT04300959 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT01974570 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01974570 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00934856 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT02555800 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00410137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01501487 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01911780 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01239901 — Predictive Biomarker (PRD): Liver iron
Study NCT01322581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00932087 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02588456 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT02262637 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06521034 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02662608 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study NCT01974765 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01915927 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04700267 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT02481479 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00001803 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT00251602 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00912665 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00852332 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00437372 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04701125 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT01898663 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT04405232 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02884635 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04195126 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04195126 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT03754049 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study NCT03044639 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study NCT03103815 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT03103815 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01360255 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT04508387 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03486145 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02081170 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT02547727 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00695734 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02675478 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02734901 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04172675 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT04390685 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02038322 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT06165588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00047242 — Predictive Biomarker (PRD): UCN mRNA
Genes: UCN
Study NCT02767622 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study NCT00686803 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01931631 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT02173262 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00869297 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03206593 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03206593 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT01439841 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05385029 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00159497 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03396042 — Predictive Biomarker (PRD): CEP290 mRNA
Genes: CEP290; BBS14; KIAA0373; NPHP6
Study NCT01042509 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT01042509 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01280201 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01280201 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01392833 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02440854 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02440854 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03243279 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01642121 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study NCT01642121 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study NCT01642121 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01642121 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT01661257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02691598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00548288 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02864680 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study NCT00098787 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01887743 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01887743 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00001237 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01860118 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT00805233 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00503399 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01960933 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study NCT03671590 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT02498210 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study NCT01633437 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04089215 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02594345 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT01779531 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01779531 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01532076 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02732795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02732795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02732795 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT01400438 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02480725 — Pharmacodynamic Biomarker (PDY): Major prion protein
Genes: PRNP; ALTPRP; PRIP; PRP
Study NCT03374618 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03773445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00005335 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study NCT00005335 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT04049227 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study NCT04106024 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT04106024 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study NCT02483871 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03839888 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study NCT00339846 — Predictive Biomarker (PRD): EFNB1 mRNA
Genes: EFNB1; EFL3; EPLG2; LERK2
Study NCT00710190 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01252238 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01920373 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02491541 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03168529 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04598854 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT01453920 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00676520 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT00924170 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT01590849 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03293680 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01778244 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04291365 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01213667 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01213667 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02623400 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study NCT05324527 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04089280 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04056507 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study NCT01153399 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00819676 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study NCT00819676 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03967119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02344810 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT03032588 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study NCT03032588 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02799472 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00477087 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01040715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01935427 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00873236 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02425865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01564784 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT00663949 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00964795 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00964795 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01032473 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00298753 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT00407680 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02270567 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study NCT01076179 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT00875368 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00875368 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT03894176 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study NCT01137162 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01137162 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04531631 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study NCT02194166 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03304457 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03304457 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT03304457 — Safety Biomarker (SAF): BDNF
Study NCT03889483 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT01824615 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT01824615 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT06180967 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT06180967 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study NCT06180967 — Predictive Biomarker (PRD): SLCO1B3 mRNA
Genes: SLCO1B3; LST2; OATP1B3; OATP8; SLC21A8
Study NCT02097459 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02097459 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03590860 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03590860 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00938587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01830777 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT04441385 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01262430 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02994888 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02994888 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04083495 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT01296594 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00170976 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01437800 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study NCT04337190 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT03783195 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03783195 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT03783195 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study NCT03783195 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02249741 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04790942 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01739855 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00004386 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study NCT04627740 — Predictive Biomarker (PRD): ALPP mRNA
Genes: ALPP; PLAP
Study NCT00643513 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00260611 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT04619407 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT05300412 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT03707561 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00202553 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00272961 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00796159 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03397186 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03397186 — Safety Biomarker (SAF): Th2 cell
Study NCT01779908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01779908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04566445 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00000157 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01925131 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT06556108 — Predictive Biomarker (PRD): ALPP mRNA
Genes: ALPP; PLAP
Study NCT06556108 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01696929 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04148898 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04148898 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04148898 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04148898 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02804100 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02342093 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04938414 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT02220387 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study NCT02220387 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study NCT02220387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02220387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02220387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01375010 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00755885 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT00507728 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT04197687 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03790423 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study NCT01264081 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study NCT02397252 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03784378 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01547780 — Predictive Biomarker (PRD): TSPO mRNA
Genes: TSPO; BZRP; MBR
Study NCT00603590 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00137839 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00359515 — Predictive Biomarker (PRD): OCRL mRNA
Genes: OCRL; OCRL1
Study NCT02871882 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02871882 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study NCT02694432 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02421198 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02113202 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02113202 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01122394 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01122394 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT02682342 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02122211 — Predictive Biomarker (PRD): CHDH mRNA
Genes: CHDH
Study NCT03774095 — Predictive Biomarker (PRD): GPR119 mRNA
Genes: GPR119
Study NCT03774095 — Predictive Biomarker (PRD): FFAR1 mRNA
Genes: FFAR1; GPR40
Study NCT03774095 — Predictive Biomarker (PRD): FFAR4 mRNA
Genes: FFAR4; GPR120; GPR129; O3FAR1; PGR4
Study NCT03774095 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT04207814 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study NCT03893344 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study NCT04073550 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT04073550 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT01422967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01397825 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT00014755 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01856101 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02142010 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00652691 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04179890 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04179890 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04622202 — Surrogate Endpoint (SUR): Blood pressure