TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30786829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27282852 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 10350666 — Surrogate Endpoint (SUR): Blood pressure
Study 28618772 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22975753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22975753 — Predictive Biomarker (PRD): CXCL13 mRNA
Genes: CXCL13; BCA1; BLC; SCYB13
Study 22975753 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 22975753 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 21251383 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11296098 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 19697301 — Surrogate Endpoint (SUR): Blood pressure
Study 17898344 — Predictive Biomarker (PRD): GRIA3 mRNA
Genes: GRIA3; GLUR3; GLURC
Study 14698135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12405649 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12405649 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29066159 — Surrogate Endpoint (SUR): Blood pressure
Study 26287149 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23003110 — Surrogate Endpoint (SUR): Serum sodium
Study 30820429 — Surrogate Endpoint (SUR): Bacterial count
Study 16877490 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 16877490 — Surrogate Endpoint (SUR): Serum calcium
Study 31938818 — Surrogate Endpoint (SUR): Bone mineral density
Study 22318468 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 22318468 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 23865591 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 16335787 — Surrogate Endpoint (SUR): Blood pressure
Study 12464091 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2302053 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2302053 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20207952 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20207952 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20207952 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 20207952 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 20207952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study 7768254 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2283645 — Surrogate Endpoint (SUR): Blood pressure
Study 26429974 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26429974 — Surrogate Endpoint (SUR): Blood pressure
Study 26429974 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19550210 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9003220 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9003220 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8492965 — Predictive Biomarker (PRD): DPEP1 mRNA
Genes: DPEP1; MDP; RDP
Study 31368893 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 11424018 — Safety Biomarker (SAF): Interleukin 12
Study 10268818 — Surrogate Endpoint (SUR): Blood pressure
Study 22192409 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 30360970 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 30360970 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 30360970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23360100 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 19153534 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 19153534 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17125829 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8400675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29703528 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 29703528 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 29703528 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 29703528 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29703528 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26321018 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 20237499 — Surrogate Endpoint (SUR): Blood pressure
Study 23414626 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 2807359 — Surrogate Endpoint (SUR): Blood pressure
Study 28608804 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 28608804 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 28608804 — Predictive Biomarker (PRD): SH2D1A mRNA
Genes: SH2D1A; DSHP; SAP
Study 28608804 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25882987 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 25882987 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 24384588 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24384588 — Surrogate Endpoint (SUR): Bone mineral density
Study 15007746 — Predictive Biomarker (PRD): AZIN2 mRNA
Genes: AZIN2; ADC; KIAA1945; ODCP
Study 24881803 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 15136063 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11214732 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11214732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24275775 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24275775 — Surrogate Endpoint (SUR): Blood pressure
Study 16603428 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 3531295 — Surrogate Endpoint (SUR): Blood pressure
Study 28708420 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 28708420 — Safety Biomarker (SAF): Reactive oxygen species
Study 8045961 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 2648890 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23680241 — Surrogate Endpoint (SUR): Probing pocket depth
Study 28891084 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10190788 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31460771 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31460771 — Surrogate Endpoint (SUR): Bone mineral density
Study 23353631 — Predictive Biomarker (PRD): NEDD4L mRNA
Genes: NEDD4L; KIAA0439; NEDL3
Study 16984385 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 15259289 — Surrogate Endpoint (SUR): Bone mineral density
Study 15259289 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15259289 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9071565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9071565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8379858 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 8379858 — Surrogate Endpoint (SUR): Bone mineral density
Study 29354970 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 29354970 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23305118 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23305118 — Surrogate Endpoint (SUR): Blood pressure
Study 18054621 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 14559846 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 14559846 — Predictive Biomarker (PRD): TFF1 mRNA
Genes: TFF1; BCEI; PS2
Study 14559846 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 14559846 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2856766 — Surrogate Endpoint (SUR): Blood pressure
Study 28419217 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16490580 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15085170 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 20560169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20560169 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20560169 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 20560169 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20560169 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 1325853 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29804882 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27007793 — Surrogate Endpoint (SUR): Blood pressure
Study 27007793 — Surrogate Endpoint (SUR): Serum potassium
Study 8081560 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23888001 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGA mRNA
Genes: FGA
Study 16729916 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23165810 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23165810 — Surrogate Endpoint (SUR): Blood pressure
Study 15842525 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15842525 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31707329 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25042661 — Surrogate Endpoint (SUR): Blood pressure
Study 3802928 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 17613583 — Surrogate Endpoint (SUR): Bone mineral density
Study 16236107 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 16236107 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11095442 — Surrogate Endpoint (SUR): Bone mineral density
Study 8720425 — Surrogate Endpoint (SUR): Blood pressure
Study 28350537 — Surrogate Endpoint (SUR): Blood pressure
Study 8173688 — Surrogate Endpoint (SUR): Blood pressure
Study 27203715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10717755 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 30512084 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 12486437 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29768301 — Predictive Biomarker (PRD): CDKAL1 mRNA
Genes: CDKAL1
Study 25482371 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24081186 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 24081186 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1773136 — Surrogate Endpoint (SUR): Bone mineral density
Study 21919984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11435050 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22823583 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 11440285 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11440285 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11440285 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28820857 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 23727631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26505573 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 19961836 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 18316153 — Surrogate Endpoint (SUR): Blood pressure
Study 12798827 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26647918 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10235417 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 8946232 — Surrogate Endpoint (SUR): Blood pressure
Study 31690988 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 31187612 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31187612 — Surrogate Endpoint (SUR): Blood pressure
Study 26350816 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26350816 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26350816 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23334063 — Surrogate Endpoint (SUR): Blood pressure
Study 19244376 — Surrogate Endpoint (SUR): Serum calcium
Study 19244376 — Surrogate Endpoint (SUR): Bone mineral density
Study 12767421 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12767421 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8400077 — Surrogate Endpoint (SUR): Blood pressure
Study 3081081 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29049890 — Predictive Biomarker (PRD): RUNX3 mRNA
Genes: RUNX3; AML2; CBFA3; PEBP2A3
Study 29049890 — Safety Biomarker (SAF): Nicotinamide phosphoribosyltransferase
Genes: NAMPT; PBEF; PBEF1
Study 29049890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22421983 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19962701 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 12826783 — Surrogate Endpoint (SUR): Blood pressure
Study 8782726 — Surrogate Endpoint (SUR): Bone mineral density
Study 1627943 — Surrogate Endpoint (SUR): Blood pressure
Study 7572708 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15539725 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24169807 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10069685 — Surrogate Endpoint (SUR): Blood pressure
Study 7628131 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1838693 — Surrogate Endpoint (SUR): Blood pressure
Study 26558544 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18068828 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 15194018 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15194018 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9568167 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8041179 — Safety Biomarker (SAF): Reactive oxygen species
Study 17039460 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17039460 — Predictive Biomarker (PRD): MUC2 mRNA
Genes: MUC2; SMUC
Study 9328361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9328361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7691912 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31122495 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 24494468 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16377095 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 27163717 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 22884641 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20211002 — Surrogate Endpoint (SUR): Serum potassium
Study 18596108 — Surrogate Endpoint (SUR): Blood pressure
Study 27811949 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27811949 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21824950 — Surrogate Endpoint (SUR): Bone mineral density
Study 17129981 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9550501 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2548222 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27373976 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 11235728 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11235728 — Surrogate Endpoint (SUR): Blood pressure
Study 18420965 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 18420965 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18420965 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12832707 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 12832707 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 8726593 — Surrogate Endpoint (SUR): Blood pressure
Study 31881702 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31881702 — Surrogate Endpoint (SUR): Blood pressure
Study 28917947 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 12603706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 8788532 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6403706 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6403706 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 6403706 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 3948638 — Surrogate Endpoint (SUR): Blood pressure
Study 3948638 — Surrogate Endpoint (SUR): Serum creatinine
Study 29842843 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 22634906 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9241098 — Surrogate Endpoint (SUR): Blood pressure
Study 3307404 — Surrogate Endpoint (SUR): Blood pressure
Study 26521182 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23890855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19423999 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19423999 — Surrogate Endpoint (SUR): Bone mineral density
Study 16919005 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 14726165 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 14726165 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 14726165 — Safety Biomarker (SAF): Reactive oxygen species
Study 14726165 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 14726165 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 3319646 — Surrogate Endpoint (SUR): Blood pressure
Study 18274692 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 16864749 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16864749 — Surrogate Endpoint (SUR): Blood pressure
Study 2587982 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31422111 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 28358246 — Surrogate Endpoint (SUR): Blood pressure
Study 25933495 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24468780 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 22999793 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 22999793 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15291660 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 2915763 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2915763 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31968346 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8247818 — Surrogate Endpoint (SUR): Blood pressure
Study 2859047 — Surrogate Endpoint (SUR): Blood pressure
Study 31444861 — Safety Biomarker (SAF): Hyaluronic acid
Study 20186829 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23652909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20053975 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 16132058 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16132058 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16199428 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3802604 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3802604 — Surrogate Endpoint (SUR): Blood pressure
Study 17034283 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17034283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17034283 — Safety Biomarker (SAF): IL-6 and IL-10
Study 15073259 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10424691 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 10511361 — Surrogate Endpoint (SUR): Blood pressure
Study 7867351 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 30383184 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 25400009 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 19752423 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15559871 — Surrogate Endpoint (SUR): Blood pressure
Study 26704522 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23868905 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12005465 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 19505393 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29650683 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 1995088 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 15784715 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272