TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29301785 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29301785 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24593225 — Surrogate Endpoint (SUR): Blood pressure
Study 24593225 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21751770 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 27655440 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 11758232 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 11758232 — Safety Biomarker (SAF): MTHFR
Study 24635880 — Surrogate Endpoint (SUR): Blood pressure
Study 22076708 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 22076708 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study 22076708 — Predictive Biomarker (PRD): ERCC5 mRNA
Genes: ERCC5; ERCM2; XPG; XPGC
Study 22076708 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 22076708 — Predictive Biomarker (PRD): XPAC mRNA
Genes: XPA; XPAC
Study 22076708 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 22076708 — Predictive Biomarker (PRD): XRCC3 mRNA
Genes: XRCC3
Study 22076708 — Predictive Biomarker (PRD): DNMT3B mRNA
Genes: DNMT3B
Study 22076708 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 22076708 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 22076708 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 11728258 — Surrogate Endpoint (SUR): Blood pressure
Study 16877536 — Surrogate Endpoint (SUR): Blood pressure
Study 9088591 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29860917 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29860917 — Predictive Biomarker (PRD): Hormone receptor
Study 26280319 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Growth/differentiation factor 8
Genes: MSTN; GDF8
Study 26280319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26280319 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22261295 — Surrogate Endpoint (SUR): Blood pressure
Study 20417659 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 12220692 — Predictive Biomarker (PRD): ACSL1 mRNA
Genes: ACSL1; FACL1; FACL2; LACS; LACS1; LACS2
Study 31290715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24385202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15556056 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15556056 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9625848 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 7877082 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24608200 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 10210973 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2196060 — Surrogate Endpoint (SUR): Blood pressure
Study 8567517 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8567517 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 19840529 — Surrogate Endpoint (SUR): Blood pressure
Study 9863541 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 8574712 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23469599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 4014191 — Surrogate Endpoint (SUR): Blood pressure
Study 27356102 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 24204790 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18434733 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 20048486 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20048486 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11560366 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 11560366 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 17178796 — Monitoring Biomarker (MOI): HBV DNA
Study 7986518 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7986518 — Surrogate Endpoint (SUR): Blood pressure
Study 23099620 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 23099620 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23099620 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29996476 — Surrogate Endpoint (SUR): Blood pressure
Study 16075984 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9883435 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 2195734 — Surrogate Endpoint (SUR): Serum creatinine
Study 154624 — Surrogate Endpoint (SUR): Blood pressure
Study 28158981 — Surrogate Endpoint (SUR): Blood pressure
Study 26232911 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26232911 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21427431 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12423709 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30554073 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 30554073 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 30554073 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 22859343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22859343 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19958854 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19958854 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15207957 — Surrogate Endpoint (SUR): Blood pressure
Study 956798 — Surrogate Endpoint (SUR): Blood pressure
Study 22761006 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 22165113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 16801465 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9082341 — Surrogate Endpoint (SUR): Blood pressure
Study 1797696 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 1797696 — Surrogate Endpoint (SUR): Blood pressure
Study 31419271 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29228436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29228436 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29228436 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26435087 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26435087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26435087 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22933498 — Safety Biomarker (SAF): Hyaluronic acid
Study 17890171 — Surrogate Endpoint (SUR): Blood pressure
Study 15337535 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21034274 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 8712391 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8712391 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 8712391 — Surrogate Endpoint (SUR): Blood pressure
Study 20636227 — Safety Biomarker (SAF): RYR1
Genes: RYR; PPP1R137
Study 14528656 — Surrogate Endpoint (SUR): Blood pressure
Study 21526663 — Surrogate Endpoint (SUR): Blood pressure
Study 9931171 — Surrogate Endpoint (SUR): Blood pressure
Study 2175139 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 18602635 — Surrogate Endpoint (SUR): Blood pressure
Study 10814600 — Surrogate Endpoint (SUR): Blood pressure
Study 29796596 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 26802087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26802087 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 26802087 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 15911902 — Surrogate Endpoint (SUR): Blood pressure
Study 12409329 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1975746 — Predictive Biomarker (PRD): TEP1 mRNA
Genes: TEP1; TLP1; TP1
Study 1975746 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31987116 — Surrogate Endpoint (SUR): Blood pressure
Study 31987116 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30367257 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23405158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21941411 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21941411 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 28627349 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21448267 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 22222469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11841067 — Surrogate Endpoint (SUR): Serum creatinine
Study 21050549 — Safety Biomarker (SAF): Human leucocyte antigen
Study 21050549 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21050549 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17698724 — Surrogate Endpoint (SUR): Blood pressure
Study 15703502 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1695308 — Surrogate Endpoint (SUR): Blood pressure
Study 30971174 — Surrogate Endpoint (SUR): Blood pressure
Study 30971174 — Surrogate Endpoint (SUR): Serum creatinine
Study 27230030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22142348 — Surrogate Endpoint (SUR): Blood pressure
Study 19197536 — Predictive Biomarker (PRD): TGM1 mRNA
Genes: TGM1; KTG
Study 19197536 — Predictive Biomarker (PRD): CYP26A1 mRNA
Genes: CYP26A1; CYP26; P450RAI1
Study 19197536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19197536 — Predictive Biomarker (PRD): KRT2 mRNA
Genes: KRT2; KRT2A; KRT2E
Study 19197536 — Predictive Biomarker (PRD): KRT4 mRNA
Genes: KRT4; CYK4
Study 14601047 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 30679232 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 30679232 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 30679232 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 30679232 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 28199463 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 20126902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20126902 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17003306 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7770136 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26882609 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 26882609 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 11958590 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11958590 — Safety Biomarker (SAF): Interleukin 12
Study 30536047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17621237 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12381833 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 10022995 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2283650 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2283650 — Surrogate Endpoint (SUR): Blood pressure
Study 29541862 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 29541862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29757889 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study 29757889 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29757889 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 10096462 — Surrogate Endpoint (SUR): Bone mineral density
Study 19632524 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7818835 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2977328 — Surrogate Endpoint (SUR): Blood pressure
Study 29127458 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 29127458 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 29127458 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26443242 — Surrogate Endpoint (SUR): Serum sodium
Study 8101772 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8101772 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3565301 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 28959471 — Surrogate Endpoint (SUR): Blood pressure
Study 28959471 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23047595 — Surrogate Endpoint (SUR): Blood pressure
Study 16484911 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 10669333 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7067184 — Surrogate Endpoint (SUR): Blood pressure
Study 21764840 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19167143 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 3042841 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 25402372 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25402372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9364693 — Monitoring Biomarker (MOI): HBV DNA
Study 17923653 — Surrogate Endpoint (SUR): Blood pressure
Study 16275486 — Surrogate Endpoint (SUR): Blood pressure
Study 7598920 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7598920 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 7598920 — Surrogate Endpoint (SUR): Blood pressure
Study 31129929 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26480548 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 26480548 — Safety Biomarker (SAF): BDNF
Study 15090391 — Predictive Biomarker (PRD): SLMAP mRNA
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 2900901 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 31932932 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 27334418 — Surrogate Endpoint (SUR): Blood pressure
Study 26636178 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 30621948 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30621948 — Surrogate Endpoint (SUR): Blood pressure
Study 26681684 — Predictive Biomarker (PRD): PHACTR3 mRNA
Genes: PHACTR3; C20orf101; SCAPIN1
Study 25194287 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 25194287 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20573405 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 20573405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17659926 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17659926 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10362152 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26921746 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 26921746 — Surrogate Endpoint (SUR): Serum potassium
Study 18678766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31955410 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31955410 — Surrogate Endpoint (SUR): Blood pressure
Study 2079570 — Monitoring Biomarker (MOI): HBV DNA
Study 24740134 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 15129731 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 15129731 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 9697664 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9697664 — Surrogate Endpoint (SUR): Serum calcium
Study 9697664 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 7924122 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 28380474 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 10215436 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26802979 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 21055277 — Surrogate Endpoint (SUR): Blood pressure
Study 1329479 — Surrogate Endpoint (SUR): Blood pressure
Study 3933397 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8758159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1949258 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17061673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21979801 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15051614 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 11551875 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11551875 — Surrogate Endpoint (SUR): Blood pressure
Study 30574801 — Safety Biomarker (SAF): BDNF
Study 23283449 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8672820 — Surrogate Endpoint (SUR): Serum creatinine
Study 31833259 — Predictive Biomarker (PRD): SLC13A5 mRNA
Genes: SLC13A5; NACT
Study 24634631 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 19576353 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19576353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15128701 — Predictive Biomarker (PRD): CRHR1 mRNA
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 15186523 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16416305 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16416305 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 8847321 — Surrogate Endpoint (SUR): Blood pressure
Study 30121304 — Surrogate Endpoint (SUR): Blood pressure
Study 7671893 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2073911 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27672029 — Surrogate Endpoint (SUR): Blood pressure
Study 11896977 — Predictive Biomarker (PRD): Fibroblast growth factor 10
Genes: FGF10
Study 19493959 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19493959 — Safety Biomarker (SAF): BDNF
Study 12086353 — Surrogate Endpoint (SUR): Bone mineral density
Study 8596098 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 8596098 — Surrogate Endpoint (SUR): Blood pressure
Study 1124532 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1124532 — Surrogate Endpoint (SUR): Blood pressure
Study 30691468 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 22079151 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 1971751 — Surrogate Endpoint (SUR): Blood pressure
Study 17679132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3904335 — Surrogate Endpoint (SUR): Blood pressure
Study 3904335 — Surrogate Endpoint (SUR): Serum potassium
Study 24484540 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19617849 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28630081 — Predictive Biomarker (PRD): CASR mRNA
Genes: CASR; GPRC2A; PCAR1
Study 28630081 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 28630081 — Surrogate Endpoint (SUR): Serum calcium
Study 26188787 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 29096777 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 26296794 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26296794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12409281 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11022421 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27795558 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 24461523 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9780616 — Surrogate Endpoint (SUR): Blood pressure
Study 16600927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16600927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3882058 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25299401 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 22512843 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 10979901 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10979901 — Safety Biomarker (SAF): Interleukin 12
Study 10979901 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8761839 — Surrogate Endpoint (SUR): Blood pressure
Study 1564133 — Surrogate Endpoint (SUR): Blood pressure
Study 29949175 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 29949175 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22452356 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 22452356 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1