TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25215556 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 25215556 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 20031551 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 20031551 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 20031551 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31606860 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31606860 — Safety Biomarker (SAF): BDNF
Study 29368594 — Surrogate Endpoint (SUR): Blood pressure
Study 22386229 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16350679 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16350679 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10232529 — Surrogate Endpoint (SUR): Serum sodium
Study 1926985 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1926985 — Surrogate Endpoint (SUR): Blood pressure
Study 29341471 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12472369 — Surrogate Endpoint (SUR): Blood pressure
Study 7604808 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7604808 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26802969 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 12016098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27632069 — Safety Biomarker (SAF): Hyaluronic acid
Study 17456571 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17456571 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20846920 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20846920 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 20846920 — Predictive Biomarker (PRD): Hormone receptor
Study 30290775 — Predictive Biomarker (PRD): TMEM37 mRNA
Genes: TMEM37; PR
Study 24299021 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 14509153 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14509153 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10204589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2671247 — Surrogate Endpoint (SUR): Blood pressure
Study 24254557 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19091331 — Surrogate Endpoint (SUR): Serum testosterone
Study 31682461 — Predictive Biomarker (PRD): APOA1 mRNA
Genes: APOA1
Study 9219047 — Surrogate Endpoint (SUR): Blood pressure
Study 30047584 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 12114432 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 7850941 — Surrogate Endpoint (SUR): Blood pressure
Study 25500935 — Predictive Biomarker (PRD): PER1 mRNA
Genes: PER1; KIAA0482; PER; RIGUI
Study 25500935 — Predictive Biomarker (PRD): PER2 mRNA
Genes: PER2; KIAA0347
Study 25500935 — Predictive Biomarker (PRD): BMAL1 mRNA
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study 22890582 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 26798983 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 17903073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17903073 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16131023 — Surrogate Endpoint (SUR): Bone mineral density
Study 26721648 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 26721648 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 23173697 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 20438867 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12574218 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31964380 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 19299790 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19299790 — Surrogate Endpoint (SUR): Blood pressure
Study 10357955 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29911741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29139301 — Surrogate Endpoint (SUR): Blood pressure
Study 20453546 — Safety Biomarker (SAF): Hyaluronic acid
Study 8740798 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21795458 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19464414 — Surrogate Endpoint (SUR): Blood pressure
Study 2645845 — Surrogate Endpoint (SUR): Blood pressure
Study 28450262 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19958541 — Predictive Biomarker (PRD): SP3 mRNA
Genes: SP3
Study 23010962 — Surrogate Endpoint (SUR): Bone mineral density
Study 12355200 — Predictive Biomarker (PRD): LYST mRNA
Genes: LYST; CHS; CHS1
Study 2229278 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 31926846 — Predictive Biomarker (PRD): KCNT1 mRNA
Genes: KCNT1; KIAA1422
Study 28963455 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21385401 — Surrogate Endpoint (SUR): Blood pressure
Study 14871466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7970234 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24625415 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 31323662 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 25918933 — Safety Biomarker (SAF): Reactive oxygen species
Study 25918933 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 1355923 — Surrogate Endpoint (SUR): Blood pressure
Study 17540991 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 17540991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17540991 — Monitoring Biomarker (MOI): Complement C4
Study 11844821 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 1691416 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10713313 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10713313 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27594841 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 15792815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11865276 — Safety Biomarker (SAF): Hyaluronic acid
Study 11257272 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 11367647 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28536866 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 26673577 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23780578 — Surrogate Endpoint (SUR): Blood pressure
Study 27502729 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27502729 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22895449 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19211712 — Surrogate Endpoint (SUR): Serum creatinine
Study 19211712 — Surrogate Endpoint (SUR): Serum potassium
Study 15895882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12703866 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8704237 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 30953836 — Predictive Biomarker (PRD): SIGLEC1 mRNA
Genes: SIGLEC1; SN
Study 24936937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24936937 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24936937 — Safety Biomarker (SAF): Interleukin 1
Study 19819118 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11093007 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 22561658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22561658 — Safety Biomarker (SAF): Interleukin 1
Study 22561658 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 10392984 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9836062 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23559220 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11098244 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 11098244 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 11098244 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1768820 — Surrogate Endpoint (SUR): Blood pressure
Study 27912940 — Surrogate Endpoint (SUR): Blood pressure
Study 1723461 — Surrogate Endpoint (SUR): Blood pressure
Study 30422259 — Surrogate Endpoint (SUR): Blood pressure
Study 23950601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23950601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23950601 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19647431 — Predictive Biomarker (PRD): SERPINB6 mRNA
Genes: SERPINB6; PI6; PTI
Study 8725414 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19907100 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17115015 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 9500318 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9500318 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8961972 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30048858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22652556 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 15879923 — Surrogate Endpoint (SUR): Bone mineral density
Study 28665556 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 11994058 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 17586596 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 2745390 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 20202971 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16791665 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 20002085 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20002085 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 29421687 — Surrogate Endpoint (SUR): Blood pressure
Study 23969907 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11498721 — Surrogate Endpoint (SUR): Blood pressure
Study 8814 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 24259042 — Surrogate Endpoint (SUR): Blood pressure
Study 19571282 — Surrogate Endpoint (SUR): Blood pressure
Study 14769732 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 14769732 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 14769732 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28247635 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 10601537 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 7851545 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 7851545 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7851545 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21544980 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21544980 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 21544980 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17446439 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17446439 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11205963 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11205963 — Surrogate Endpoint (SUR): Blood pressure
Study 26490089 — Surrogate Endpoint (SUR): Blood pressure
Study 22653220 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9056614 — Surrogate Endpoint (SUR): Blood pressure
Study 9056614 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30197313 — Predictive Biomarker (PRD): CLPB mRNA
Genes: CLPB; HSP78; SKD3
Study 12860578 — Surrogate Endpoint (SUR): Blood pressure
Study 12860578 — Surrogate Endpoint (SUR): Serum creatinine
Study 12860578 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10375935 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10375935 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30307410 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 20825615 — Surrogate Endpoint (SUR): Blood pressure
Study 17879531 — Surrogate Endpoint (SUR): Bone mineral density
Study 26016870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23436260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17293085 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 16990657 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 29402762 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27609408 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 22234043 — Surrogate Endpoint (SUR): Blood pressure
Study 18086760 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 2159694 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29768119 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 16320790 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 29455482 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 25563584 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 25563584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1799922 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1799922 — Surrogate Endpoint (SUR): Blood pressure
Study 6274473 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 6274473 — Surrogate Endpoint (SUR): Blood pressure
Study 26736024 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 21917440 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15198477 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15198477 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 30138384 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27009936 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12771603 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12771603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12771603 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1316401 — Surrogate Endpoint (SUR): Blood pressure
Study 26613768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26613768 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26613768 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26613768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21427425 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18834717 — Safety Biomarker (SAF): DRD2
Study 17555947 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7936513 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26337539 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 26337539 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26337539 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21138462 — Surrogate Endpoint (SUR): Serum testosterone
Study 15760313 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 11962564 — Surrogate Endpoint (SUR): Blood pressure
Study 27553181 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18549330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1954075 — Surrogate Endpoint (SUR): Blood pressure
Study 22896665 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12372673 — Surrogate Endpoint (SUR): Blood pressure
Study 9822045 — Surrogate Endpoint (SUR): Blood pressure
Study 8017470 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8017470 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31555976 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31555976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16469323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16469323 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20601897 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 20601897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31924332 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23731996 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 8004841 — Surrogate Endpoint (SUR): Blood pressure
Study 20592644 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 15913800 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15913800 — Safety Biomarker (SAF): Th2 cell
Study 9926970 — Surrogate Endpoint (SUR): Bone mineral density
Study 7489963 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7489963 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 17372126 — Surrogate Endpoint (SUR): Bone mineral density
Study 25388643 — Safety Biomarker (SAF): Hyaluronic acid
Study 22381051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22381051 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6794083 — Surrogate Endpoint (SUR): Blood pressure
Study 15476485 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 2565995 — Surrogate Endpoint (SUR): Blood pressure
Study 23921307 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23921307 — Surrogate Endpoint (SUR): Blood pressure
Study 23921307 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10434906 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8140873 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 3555604 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 3555604 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 21478817 — Surrogate Endpoint (SUR): Blood pressure
Study 2856785 — Surrogate Endpoint (SUR): Blood pressure
Study 2856785 — Surrogate Endpoint (SUR): Serum sodium
Study 30650326 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 19175372 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12375395 — Predictive Biomarker (PRD): ACSL4 mRNA
Genes: ACSL4; ACS4; FACL4; LACS4
Study 8605054 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 813411 — Surrogate Endpoint (SUR): Blood pressure
Study 27333986 — Surrogate Endpoint (SUR): Blood pressure
Study 19380449 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 19380449 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19380449 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 17050503 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14524646 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14524646 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 14524646 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 14524646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9066355 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 9066355 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27399197 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20964867 — Surrogate Endpoint (SUR): Bone mineral density
Study 12584032 — Surrogate Endpoint (SUR): Bone mineral density
Study 7687716 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 7687716 — Surrogate Endpoint (SUR): Blood pressure
Study 27285349 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27285349 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 18243665 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 18243665 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ADAM11 mRNA
Genes: ADAM11; MDC
Study 18243665 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 18243665 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 18243665 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 18243665 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG