TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27908967 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 17519152 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 15219640 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 15219640 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 15219640 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11579345 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30037818 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 30037818 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 30037818 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 28182502 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 24094463 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 18086050 — Safety Biomarker (SAF): Hyaluronic acid
Study 15537681 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15537681 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9632998 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28627793 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 28627793 — Surrogate Endpoint (SUR): Blood pressure
Study 16253026 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16253026 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 16253026 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 29246219 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 29246219 — Predictive Biomarker (PRD): MMP13 mRNA
Genes: MMP13
Study 29246219 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 25937516 — Surrogate Endpoint (SUR): Blood pressure
Study 22097612 — Monitoring Biomarker (MOI): HBV DNA
Study 16537846 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11203813 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 26955982 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 12777360 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10857365 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11835027 — Surrogate Endpoint (SUR): Serum testosterone
Study 11835027 — Surrogate Endpoint (SUR): Blood pressure
Study 3034034 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3034034 — Surrogate Endpoint (SUR): Blood pressure
Study 24398888 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24398888 — Surrogate Endpoint (SUR): Blood pressure
Study 15919007 — Surrogate Endpoint (SUR): Blood pressure
Study 1920782 — Surrogate Endpoint (SUR): Blood pressure
Study 8005815 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10953 — Surrogate Endpoint (SUR): Blood pressure
Study 28395180 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18840027 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12574793 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12574793 — Surrogate Endpoint (SUR): Blood pressure
Study 27520400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27520400 — Surrogate Endpoint (SUR): Blood pressure
Study 27520400 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27520400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22425507 — Surrogate Endpoint (SUR): Bone mineral density
Study 19024795 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28597302 — Surrogate Endpoint (SUR): Blood pressure
Study 19350266 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16458092 — Surrogate Endpoint (SUR): Blood pressure
Study 15303255 — Surrogate Endpoint (SUR): Blood pressure
Study 9813876 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31821741 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study 23061976 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 25411740 — Surrogate Endpoint (SUR): Probing pocket depth
Study 3082257 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 31520633 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 21296957 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study 19467834 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17088135 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 17088135 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 16368340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16368340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12600870 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 29659116 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 27572136 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 24699248 — Predictive Biomarker (PRD): GPR119 mRNA
Genes: GPR119
Study 24699248 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 24699248 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21337116 — Surrogate Endpoint (SUR): Blood pressure
Study 8904257 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9322826 — Surrogate Endpoint (SUR): Blood pressure
Study 16834839 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 10693734 — Surrogate Endpoint (SUR): Blood pressure
Study 9490144 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 9490144 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18682410 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15591298 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12616317 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12616317 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28514624 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 28514624 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21542721 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 17205817 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10966540 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1713484 — Surrogate Endpoint (SUR): Plasma ammonia
Study 31725942 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 31050355 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 23389112 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17540191 — Surrogate Endpoint (SUR): Blood pressure
Study 11451215 — Surrogate Endpoint (SUR): Blood pressure
Study 15602503 — Surrogate Endpoint (SUR): Blood pressure
Study 5320590 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 5320590 — Surrogate Endpoint (SUR): Blood pressure
Study 30753377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19034493 — Monitoring Biomarker (MOI): Procalcitonin
Study 9240877 — Surrogate Endpoint (SUR): Bone mineral density
Study 24282608 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 14561238 — Surrogate Endpoint (SUR): Blood pressure
Study 10971167 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21616737 — Surrogate Endpoint (SUR): Blood pressure
Study 15882280 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11172138 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2455099 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 14680665 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24118885 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 24118885 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 20409605 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 18331385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12582393 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 10684406 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6404404 — Surrogate Endpoint (SUR): Blood pressure
Study 28743343 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 25567758 — Surrogate Endpoint (SUR): Blood pressure
Study 19623782 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 22189199 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 22189199 — Predictive Biomarker (PRD): NR1H3 mRNA
Genes: NR1H3; LXRA
Study 22189199 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19958238 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 19958238 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19958238 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 17400672 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 17400672 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9471040 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2375235 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 31298405 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24981180 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24981180 — Surrogate Endpoint (SUR): Blood pressure
Study 7611822 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7611822 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31441893 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 27683185 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 27683185 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 27683185 — Predictive Biomarker (PRD): CYP27B1 mRNA
Genes: CYP27B1; CYP1ALPHA; CYP27B
Study 15532847 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15532847 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21076278 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16290928 — Predictive Biomarker (PRD): TAC1 mRNA
Genes: TAC1; NKA; NKNA; TAC2
Study 16290928 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 19735754 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 19735754 — Surrogate Endpoint (SUR): Bone mineral density
Study 21880792 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30052315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8471083 — Surrogate Endpoint (SUR): Blood pressure
Study 26081066 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21298384 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 19695188 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29944164 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 9861597 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 31985313 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 7977125 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 7977125 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7977125 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30595354 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 23073950 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15934992 — Surrogate Endpoint (SUR): Serum potassium
Study 10075273 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8598548 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8598548 — Predictive Biomarker (PRD): SPINK1 mRNA
Genes: SPINK1; PSTI
Study 27852036 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27852036 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 27852036 — Predictive Biomarker (PRD): GALE mRNA
Genes: GALE
Study 10073771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10073771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10073771 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31221225 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 31221225 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31221225 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 31221225 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18670855 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 10498160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8869791 — Predictive Biomarker (PRD): C9 mRNA
Genes: C9
Study 26216648 — Safety Biomarker (SAF): Interleukin 1
Study 26216648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25135060 — Safety Biomarker (SAF): 51Cr-EDTA
Study 19059660 — Surrogate Endpoint (SUR): Blood pressure
Study 29326420 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 22051332 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22051332 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 8062314 — Surrogate Endpoint (SUR): Blood pressure
Study 18524823 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18524823 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18524823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18524823 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30617786 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 27411333 — Surrogate Endpoint (SUR): Blood pressure
Study 20500126 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20500126 — Surrogate Endpoint (SUR): Blood pressure
Study 2699147 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 91778 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 22760005 — Predictive Biomarker (PRD): MAG mRNA
Genes: MAG; GMA
Study 21204103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21204103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19138505 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 8504634 — Surrogate Endpoint (SUR): Plasma ammonia
Study 7305608 — Surrogate Endpoint (SUR): Blood pressure
Study 24611442 — Surrogate Endpoint (SUR): Blood pressure
Study 10373219 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 10373219 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21454149 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 10782811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10782811 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 10782811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31481453 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26920601 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 26920601 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26920601 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11160538 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 14650363 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1460749 — Surrogate Endpoint (SUR): Blood pressure
Study 3520308 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 3520308 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12904517 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12904517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28340157 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 23677817 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 19934707 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8724107 — Surrogate Endpoint (SUR): Blood pressure
Study 2035283 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2035283 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 28143413 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 19433778 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19433778 — Surrogate Endpoint (SUR): Blood pressure
Study 17766632 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11222463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7912097 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2680274 — Surrogate Endpoint (SUR): Blood pressure
Study 7019840 — Surrogate Endpoint (SUR): Blood pressure
Study 21876071 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 21876071 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 21876071 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6375889 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6375889 — Surrogate Endpoint (SUR): Blood pressure
Study 24064970 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 24064970 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study 19295325 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11350409 — Predictive Biomarker (PRD): GAPDH mRNA
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 11350409 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23497981 — Surrogate Endpoint (SUR): Blood pressure
Study 12601631 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10604887 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 25354581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17555530 — Surrogate Endpoint (SUR): Bone mineral density
Study 10080586 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1776591 — Surrogate Endpoint (SUR): Blood pressure
Study 29566104 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16710349 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 16710349 — Predictive Biomarker (PRD): CD2AP mRNA
Genes: CD2AP
Study 16710349 — Predictive Biomarker (PRD): NPHS1 mRNA
Genes: NPHS1; NPHN
Study 16710349 — Predictive Biomarker (PRD): NPHS2 mRNA
Genes: NPHS2
Study 11127083 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 26212672 — Surrogate Endpoint (SUR): Serum sodium
Study 23315907 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19136369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31002537 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 16965241 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8349326 — Surrogate Endpoint (SUR): Blood pressure
Study 24162762 — Safety Biomarker (SAF): Hyaluronic acid
Study 20649975 — Predictive Biomarker (PRD): HOXB13 mRNA
Genes: HOXB13
Study 20649975 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10375338 — Surrogate Endpoint (SUR): Bone mineral density
Study 30307514 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 9701277 — Surrogate Endpoint (SUR): Blood pressure
Study 23204161 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21421658 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22154650 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 8403797 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27134062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27134062 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 20937148 — Surrogate Endpoint (SUR): Blood pressure
Study 24969712 — Surrogate Endpoint (SUR): Blood pressure
Study 16762801 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10453433 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23637967 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 14683737 — Surrogate Endpoint (SUR): Blood pressure
Study 31470806 — Surrogate Endpoint (SUR): Blood pressure
Study 25295719 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17563739 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17563739 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15712603 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8668449 — Surrogate Endpoint (SUR): Blood pressure
Study 20336302 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 7588508 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 31948926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23512440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23512440 — Surrogate Endpoint (SUR): Blood pressure
Study 10552270 — Surrogate Endpoint (SUR): Blood pressure
Study 9505937 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27342888 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27342888 — Surrogate Endpoint (SUR): Blood pressure