TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1951242 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 19896213 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 19896213 — Safety Biomarker (SAF): DRD2
Study 11271785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25592656 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30204244 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 19416992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15127325 — Surrogate Endpoint (SUR): Blood pressure
Study 11256540 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11256540 — Surrogate Endpoint (SUR): Serum creatinine
Study 30804129 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26143297 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 26143297 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 11421998 — Surrogate Endpoint (SUR): Blood pressure
Study 3511650 — Surrogate Endpoint (SUR): Blood pressure
Study 3511650 — Surrogate Endpoint (SUR): Serum potassium
Study 23413535 — Surrogate Endpoint (SUR): Blood pressure
Study 18443034 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 15983224 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 29056249 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29056249 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29056249 — Predictive Biomarker (PRD): CMIP mRNA
Genes: CMIP; KIAA1694; TCMIP
Study 29056249 — Predictive Biomarker (PRD): CXCR5 mRNA
Genes: CXCR5; BLR1; MDR15
Study 15752944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15752944 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2971131 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 2971131 — Surrogate Endpoint (SUR): Blood pressure
Study 27218270 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 27218270 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21707573 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22464340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17530097 — Predictive Biomarker (PRD): HSPD1 mRNA
Genes: HSPD1; HSP60
Study 1343377 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16439720 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21993599 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 802649 — Surrogate Endpoint (SUR): Blood pressure
Study 19736473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17009077 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 17009077 — Surrogate Endpoint (SUR): Serum creatinine
Study 17009077 — Surrogate Endpoint (SUR): Blood pressure
Study 26782853 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 26782853 — Surrogate Endpoint (SUR): Serum calcium
Study 17767636 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28676211 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 2301216 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19283449 — Surrogate Endpoint (SUR): Serum creatinine
Study 2191783 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 22996693 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 22996693 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 22996693 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 1751651 — Surrogate Endpoint (SUR): Blood pressure
Study 30388595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30388595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30388595 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 30388595 — Safety Biomarker (SAF): Interleukin 1
Study 30195882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15793869 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15793869 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 15793869 — Monitoring Biomarker (MOI): HBV DNA
Study 4054195 — Surrogate Endpoint (SUR): Blood pressure
Study 21700935 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21700935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17238390 — Surrogate Endpoint (SUR): Blood pressure
Study 9003815 — Surrogate Endpoint (SUR): Blood pressure
Study 3068400 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27455835 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 23011562 — Surrogate Endpoint (SUR): Blood pressure
Study 21510583 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28493293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 28493293 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 28493293 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 21863617 — Surrogate Endpoint (SUR): Blood pressure
Study 17187936 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8186281 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25747197 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25747197 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 1184719 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 19430945 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19430945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19430945 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19430945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19430945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19430945 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22457015 — Surrogate Endpoint (SUR): Blood pressure
Study 12366781 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 12366781 — Safety Biomarker (SAF): Interleukin 12
Study 12366781 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24851582 — Surrogate Endpoint (SUR): Blood pressure
Study 31264950 — Surrogate Endpoint (SUR): Serum creatinine
Study 23831913 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21183326 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9869017 — Surrogate Endpoint (SUR): Blood pressure
Study 31408531 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 31408531 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 31408531 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 28334771 — Surrogate Endpoint (SUR): Serum testosterone
Study 16582575 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16582575 — Surrogate Endpoint (SUR): Serum creatinine
Study 11789206 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11789206 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11511333 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 27525826 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27525826 — Safety Biomarker (SAF): BDNF
Study 16378562 — Surrogate Endpoint (SUR): Blood pressure
Study 29257986 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30919909 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27865639 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 27865639 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 27865639 — Predictive Biomarker (PRD): GNL3 mRNA
Genes: GNL3; E2IG3; NS
Study 27865639 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 12508046 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1517614 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 6712030 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29879048 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25027338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25027338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25027338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25027338 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 25027338 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 25027338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23636616 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 19002467 — Surrogate Endpoint (SUR): Serum creatinine
Study 2628537 — Surrogate Endpoint (SUR): Blood pressure
Study 30205020 — Surrogate Endpoint (SUR): Bone mineral density
Study 28039545 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 25738212 — Surrogate Endpoint (SUR): Blood pressure
Study 21872439 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11604622 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 11604622 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 29483080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27363733 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27363733 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24120618 — Surrogate Endpoint (SUR): Blood pressure
Study 31287010 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 29871798 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 22033897 — Safety Biomarker (SAF): Hyaluronic acid
Study 2184789 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2184789 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20540445 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20540445 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 10715786 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 7767523 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 31755959 — Predictive Biomarker (PRD): IFIH1 mRNA
Genes: IFIH1; MDA5; RH116
Study 19710199 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19710199 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15115249 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15115249 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27127117 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12871461 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 25455039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25455039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10673249 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28719717 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 28719717 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 3046815 — Surrogate Endpoint (SUR): Blood pressure
Study 3046815 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 27492015 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25475357 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 14662281 — Surrogate Endpoint (SUR): Bone mineral density
Study 31422507 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 30343028 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 30343028 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20799043 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 20799043 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 20799043 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 18830816 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27211272 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 27211272 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 17514537 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17514537 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10052485 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10052485 — Surrogate Endpoint (SUR): Blood pressure
Study 16053664 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16053664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22046862 — Surrogate Endpoint (SUR): Blood pressure
Study 2390921 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 2390921 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 25598270 — Safety Biomarker (SAF): MTHFR
Study 15046934 — Safety Biomarker (SAF): Hyaluronic acid
Study 7927488 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 19552598 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 19552598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19552598 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17349072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24990422 — Surrogate Endpoint (SUR): Blood pressure
Study 2243148 — Surrogate Endpoint (SUR): Blood pressure
Study 29667330 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25787780 — Surrogate Endpoint (SUR): Blood pressure
Study 22401327 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18729835 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15856409 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15856409 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15856409 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 15856409 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 14585254 — Predictive Biomarker (PRD): CLN3 mRNA
Genes: CLN3; BTS
Study 8112371 — Surrogate Endpoint (SUR): Blood pressure
Study 24053794 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22464673 — Predictive Biomarker (PRD): FSCN1 mRNA
Genes: FSCN1; FAN1; HSN; SNL
Study 22464673 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study 22464673 — Predictive Biomarker (PRD): NMES1 mRNA
Genes: NMES1; C15orf48
Study 22464673 — Predictive Biomarker (PRD): MX1 mRNA
Genes: MX1
Study 22464673 — Predictive Biomarker (PRD): TRAF1 mRNA
Genes: TRAF1; EBI6
Study 22464673 — Predictive Biomarker (PRD): Phospholipase A2 inhibitory protein
Genes: ANXA1; ANX1; LPC1
Study 22464673 — Predictive Biomarker (PRD): TSC22D3 mRNA
Genes: TSC22D3; DSIPI; GILZ
Study 22464673 — Predictive Biomarker (PRD): F13A1 mRNA
Genes: F13A1; F13A
Study 22464673 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 22464673 — Predictive Biomarker (PRD): STAB1 mRNA
Genes: STAB1; FEEL1; KIAA0246
Study 20973922 — Surrogate Endpoint (SUR): Serum sodium
Study 18242584 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15058795 — Predictive Biomarker (PRD): SMARCA2 mRNA
Genes: SMARCA2; BAF190B; BRM; SNF2A; SNF2L2
Study 29529897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29529897 — Safety Biomarker (SAF): T-cell specific protein RANTES
Genes: CCL5; D17S136E; SCYA5
Study 24940825 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19850944 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 7845026 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24521775 — Surrogate Endpoint (SUR): Serum creatinine
Study 19506333 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 9627948 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 8185271 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28012910 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28012910 — Surrogate Endpoint (SUR): Blood pressure
Study 11127459 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1396832 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17768460 — Surrogate Endpoint (SUR): Blood pressure
Study 15080014 — Surrogate Endpoint (SUR): Blood pressure
Study 23034957 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 20550022 — Surrogate Endpoint (SUR): Blood pressure
Study 1094320 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27399127 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 27399127 — Surrogate Endpoint (SUR): Bone mineral density
Study 27399127 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 707580 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 19183161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19183161 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9732070 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9732070 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22621316 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22621316 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17603846 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 17603846 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 17603846 — Predictive Biomarker (PRD): CCR9 mRNA
Genes: CCR9; GPR28
Study 11524061 — Surrogate Endpoint (SUR): Blood pressure
Study 8596135 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28503774 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 28503774 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28370407 — Surrogate Endpoint (SUR): Bone mineral density
Study 22290681 — Surrogate Endpoint (SUR): Blood pressure
Study 11316108 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28992127 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study 28992127 — Predictive Biomarker (PRD): PKD2 mRNA
Genes: PKD2; TRPP2
Study 28992127 — Surrogate Endpoint (SUR): Total kidney volume
Study 21393063 — Pharmacodynamic Biomarker (PDY): Peripheral myelin protein 22
Genes: PMP22; GAS3
Study 7171533 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28010246 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17827369 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29807936 — Surrogate Endpoint (SUR): Blood pressure
Study 26720473 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21509050 — Surrogate Endpoint (SUR): Blood pressure
Study 12818462 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 12818462 — Surrogate Endpoint (SUR): Bone mineral density
Study 8769685 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24536039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24536039 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18197497 — Predictive Biomarker (PRD): AQP3 mRNA
Genes: AQP3
Study 18197497 — Predictive Biomarker (PRD): AQP9 mRNA
Genes: AQP9; SSC1
Study 12630074 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30699971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30699971 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23551992 — Surrogate Endpoint (SUR): Blood pressure
Study 23551992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23551992 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 21342323 — Surrogate Endpoint (SUR): Bone mineral density
Study 21342323 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 28232237 — Predictive Biomarker (PRD): NE
Study 21878470 — Predictive Biomarker (PRD): DISC1 mRNA
Genes: DISC1; KIAA0457
Study 7744190 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2286480 — Surrogate Endpoint (SUR): Blood pressure
Study 23113482 — Surrogate Endpoint (SUR): New morphometric vertebral fractures
Study 23113482 — Surrogate Endpoint (SUR): Bone mineral density
Study 20166859 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 8703663 — Surrogate Endpoint (SUR): Blood pressure
Study 19954718 — Surrogate Endpoint (SUR): Bone mineral density
Study 19954718 — Predictive Biomarker (PRD): Intact parathyroid hormone