TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23660099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23660099 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23660099 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17704850 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15078472 — Monitoring Biomarker (MOI): HBV DNA
Study 11204308 — Surrogate Endpoint (SUR): Blood pressure
Study 11204308 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11204308 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2173470 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 19499738 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15213559 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23269536 — Predictive Biomarker (PRD): SLC45A3 mRNA
Genes: SLC45A3; PCANAP6; PRST
Study 23269536 — Predictive Biomarker (PRD): MSMB mRNA
Genes: MSMB; PRSP
Study 23269536 — Predictive Biomarker (PRD): KLK3 mRNA
Genes: KLK3; APS
Study 21881323 — Surrogate Endpoint (SUR): Serum creatinine
Study 22906130 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 12499885 — Safety Biomarker (SAF): Human leucocyte antigen
Study 7636320 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26479144 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 21831277 — Surrogate Endpoint (SUR): Blood pressure
Study 15312405 — Surrogate Endpoint (SUR): Blood pressure
Study 9007680 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30144037 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 26556571 — Surrogate Endpoint (SUR): Bacterial count
Study 11559968 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9241288 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 22447019 — Surrogate Endpoint (SUR): Blood pressure
Study 14578140 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 26917956 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 1639045 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6440460 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 19042044 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15925032 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 28207516 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26481293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9642517 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 9642517 — Surrogate Endpoint (SUR): Serum creatinine
Study 23933006 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 20888091 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 20888091 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20888091 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12562873 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3898930 — Surrogate Endpoint (SUR): Blood pressure
Study 12068794 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 31448737 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 29241379 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 10712710 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22857752 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 20500899 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 2246098 — Predictive Biomarker (PRD): ALPK3 mRNA
Genes: ALPK3; KIAA1330; MAK
Study 26491273 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23392463 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 24688618 — Surrogate Endpoint (SUR): Blood pressure
Study 17534745 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16886928 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 16886928 — Surrogate Endpoint (SUR): Blood pressure
Study 11112935 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31679186 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28017170 — Surrogate Endpoint (SUR): Blood pressure
Study 14973304 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 14973304 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 17318795 — Surrogate Endpoint (SUR): Blood pressure
Study 14706485 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9175946 — Predictive Biomarker (PRD): KCNH2 mRNA
Genes: KCNH2; ERG; ERG1; HERG
Study 4065179 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31566843 — Surrogate Endpoint (SUR): Pathological complete response
Study 27801825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27801825 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19929980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19929980 — Surrogate Endpoint (SUR): Blood pressure
Study 14675576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14675576 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30222541 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30222541 — Predictive Biomarker (PRD): HINT1 mRNA
Genes: HINT1; HINT; PKCI1; PRKCNH1
Study 7668311 — Surrogate Endpoint (SUR): Serum calcium
Study 29843528 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27852684 — Surrogate Endpoint (SUR): Blood pressure
Study 14531504 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 14531504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8880817 — Surrogate Endpoint (SUR): Blood pressure
Study 26902092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26902092 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 26902092 — Surrogate Endpoint (SUR): Bone mineral density
Study 16167789 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 6147300 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 23175563 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 11100000 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8775351 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 8775351 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8775351 — Surrogate Endpoint (SUR): Blood pressure
Study 6724661 — Surrogate Endpoint (SUR): Blood pressure
Study 17596273 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19207722 — Surrogate Endpoint (SUR): Blood pressure
Study 11370797 — Surrogate Endpoint (SUR): Blood pressure
Study 9198730 — Surrogate Endpoint (SUR): Blood pressure
Study 29900829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20099281 — Predictive Biomarker (PRD): MTRR mRNA
Genes: MTRR
Study 9919319 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 30322847 — Surrogate Endpoint (SUR): Serum creatinine
Study 30322847 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21332375 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 3201506 — Surrogate Endpoint (SUR): Blood pressure
Study 25808588 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16691029 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16691029 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14552534 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 31053943 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24330343 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 781495 — Surrogate Endpoint (SUR): Blood pressure
Study 28575274 — Surrogate Endpoint (SUR): Blood pressure
Study 26282657 — Surrogate Endpoint (SUR): Blood pressure
Study 22123798 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26439785 — Surrogate Endpoint (SUR): Serum creatinine
Study 25317071 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15602501 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 9802935 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 23318559 — Predictive Biomarker (PRD): CHRNA7 mRNA
Genes: CHRNA7; NACHRA7
Study 21113584 — Surrogate Endpoint (SUR): Bone mineral density
Study 14716843 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14716843 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 14716843 — Predictive Biomarker (PRD): C9 mRNA
Genes: C9
Study 14716843 — Monitoring Biomarker (MOI): HBV DNA
Study 17997313 — Surrogate Endpoint (SUR): Blood pressure
Study 24401051 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 1859490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6356900 — Surrogate Endpoint (SUR): Blood pressure
Study 20185426 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12161488 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10198397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10198397 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29511965 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 29511965 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 23079690 — Surrogate Endpoint (SUR): Bone mineral density
Study 6143188 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 24408116 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24408116 — Surrogate Endpoint (SUR): Serum potassium
Study 12061947 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 23543663 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 23543663 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 23543663 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23543663 — Surrogate Endpoint (SUR): Serum calcium
Study 23543663 — Surrogate Endpoint (SUR): Bone mineral density
Study 19787287 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11561116 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3034469 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3034469 — Surrogate Endpoint (SUR): Blood pressure
Study 25072617 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25072617 — Surrogate Endpoint (SUR): Bone mineral density
Study 28679142 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23381685 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 22180523 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 16372352 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 16372352 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 16372352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16372352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8800583 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8800583 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8800583 — Surrogate Endpoint (SUR): Blood pressure
Study 1863505 — Surrogate Endpoint (SUR): Serum creatinine
Study 1863505 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 3137605 — Surrogate Endpoint (SUR): Blood pressure
Study 29675430 — Predictive Biomarker (PRD): FGF7 mRNA
Genes: FGF7; KGF
Study 29675430 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29675430 — Predictive Biomarker (PRD): ACTA2 mRNA
Genes: ACTA2; ACTSA; ACTVS; GIG46
Study 19589122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19589122 — Surrogate Endpoint (SUR): Blood pressure
Study 19589122 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25555381 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9562159 — Surrogate Endpoint (SUR): Blood pressure
Study 8202883 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8202883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8202883 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 25330161 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15563538 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 12539211 — Safety Biomarker (SAF): DRD3
Study 10628188 — Surrogate Endpoint (SUR): Blood pressure
Study 26871379 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 21777924 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21777924 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12191852 — Surrogate Endpoint (SUR): Bone mineral density
Study 2222242 — Surrogate Endpoint (SUR): Blood pressure
Study 360819 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 28260864 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 23260855 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 8880045 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7197979 — Surrogate Endpoint (SUR): Blood pressure
Study 15121876 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 15121876 — Predictive Biomarker (PRD): LIF mRNA
Genes: LIF; HILDA
Study 15121876 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15121876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11448466 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 8822534 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 29501363 — Surrogate Endpoint (SUR): Pathological complete response
Study 27922288 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 17568245 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17568245 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9973020 — Surrogate Endpoint (SUR): Serum creatinine
Study 1960071 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7988776 — Surrogate Endpoint (SUR): Blood pressure
Study 154749 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 154749 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30952794 — Predictive Biomarker (PRD): KLK3 mRNA
Genes: KLK3; APS
Study 18401214 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16095054 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16095054 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2265248 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27687519 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28480382 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28480382 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28480382 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28480382 — Safety Biomarker (SAF): IL-6 and IL-10
Study 23301057 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 23301057 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 23301057 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11133640 — Surrogate Endpoint (SUR): Blood pressure
Study 9643276 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18303486 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 2880811 — Surrogate Endpoint (SUR): Serum creatinine
Study 18280726 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1310913 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1310913 — Surrogate Endpoint (SUR): Blood pressure
Study 18005286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 18005286 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31957838 — Predictive Biomarker (PRD): ENO1 mRNA
Genes: ENO1; ENO1L1; MBPB1; MPB1
Study 26782685 — Surrogate Endpoint (SUR): Bone mineral density
Study 22288732 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22288732 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7886648 — Surrogate Endpoint (SUR): Blood pressure
Study 23507258 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31832778 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26733110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17650794 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 17650794 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31701610 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 27329448 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 29430176 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 20964833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20964833 — Surrogate Endpoint (SUR): Bone mineral density
Study 12077742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12077742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12077742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8588499 — Surrogate Endpoint (SUR): Blood pressure
Study 27489211 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22610853 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22610853 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22610853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22610853 — Surrogate Endpoint (SUR): Serum triglycerides
Study 14679674 — Surrogate Endpoint (SUR): Blood pressure
Study 21392615 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21392615 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23447123 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 10678543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10678543 — Surrogate Endpoint (SUR): Blood pressure
Study 9549634 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9549634 — Surrogate Endpoint (SUR): Blood pressure
Study 8349942 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8349942 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 8349942 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8349942 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3484691 — Predictive Biomarker (PRD): SDC1 mRNA
Genes: SDC1; SDC
Study 26092233 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11936063 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6817771 — Surrogate Endpoint (SUR): Blood pressure
Study 18057307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18057307 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 2162875 — Surrogate Endpoint (SUR): Blood pressure
Study 7225165 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24128379 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 373395 — Surrogate Endpoint (SUR): Blood pressure
Study 31153360 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24448227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24448227 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24448227 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21917822 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 7648653 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28210090 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21994957 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 30711961 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 12573306 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 12573306 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 2885022 — Surrogate Endpoint (SUR): Blood pressure
Study 31278429 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 25324251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25324251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2