TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16027532 — Surrogate Endpoint (SUR): Blood pressure
Study 10327509 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10327509 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8723394 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8723394 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 8723394 — Surrogate Endpoint (SUR): Blood pressure
Study 8723394 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27025001 — Surrogate Endpoint (SUR): Blood pressure
Study 25460030 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 22903517 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24186848 — Surrogate Endpoint (SUR): Blood pressure
Study 30961956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15914128 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10069630 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10069630 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 10069630 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 10069630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10069630 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 10069630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8535309 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25210881 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18940395 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28761118 — Surrogate Endpoint (SUR): Serum creatinine
Study 25315887 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25315887 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 25315887 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17586303 — Surrogate Endpoint (SUR): Blood pressure
Study 15883561 — Surrogate Endpoint (SUR): Serum calcium
Study 9506313 — Predictive Biomarker (PRD): CORT mRNA
Genes: CORT; UNQ307/PRO350
Study 9506313 — Surrogate Endpoint (SUR): Blood pressure
Study 23234631 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23234631 — Surrogate Endpoint (SUR): Bone mineral density
Study 12723054 — Surrogate Endpoint (SUR): Blood pressure
Study 19651449 — Surrogate Endpoint (SUR): Blood pressure
Study 9049578 — Surrogate Endpoint (SUR): Blood pressure
Study 29509641 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 31865423 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31865423 — Surrogate Endpoint (SUR): Blood pressure
Study 31865423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28497325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23963965 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18795965 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10449279 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2260046 — Surrogate Endpoint (SUR): Blood pressure
Study 26872295 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 26872295 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26872295 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26872295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26872295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26872295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10416558 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31358387 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 19650425 — Surrogate Endpoint (SUR): Blood pressure
Study 15111679 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 9814494 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21712835 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18494727 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 14521739 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 8960446 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 2467134 — Surrogate Endpoint (SUR): Blood pressure
Study 27442085 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 15963746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15963746 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28836866 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 28836866 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 16383037 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 16383037 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 28855224 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 21813074 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21813074 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 21813074 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20001608 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20001608 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15448205 — Predictive Biomarker (PRD): ZMYM2 mRNA
Genes: ZMYM2; FIM; RAMP; ZNF198
Study 15448205 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 15448205 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 15448205 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 7957502 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3661642 — Surrogate Endpoint (SUR): Blood pressure
Study 28431543 — Predictive Biomarker (PRD): GARS1 mRNA
Genes: GARS1; GARS
Study 15944423 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30079814 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23295313 — Surrogate Endpoint (SUR): Serum uric acid
Study 7627485 — Surrogate Endpoint (SUR): Bone mineral density
Study 29869444 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 18277020 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12588635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12588635 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28685553 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 28685553 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 16292592 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 15061398 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 15061398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9413087 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 2939221 — Surrogate Endpoint (SUR): Blood pressure
Study 11683039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21323540 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17214343 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 10881252 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 30971374 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30971374 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29953441 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 29953441 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 29953441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): RASSF1A
Genes: RASSF1; NORE2A; REH3P21; RDA32; 123F2
Study 24126172 — Surrogate Endpoint (SUR): Blood pressure
Study 6391154 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 30318624 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 24176529 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24176529 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31765956 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30426311 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28318624 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25487082 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25487082 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 25487082 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 23172889 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 21492400 — Surrogate Endpoint (SUR): Serum testosterone
Study 12809566 — Predictive Biomarker (PRD): TNFA
Genes: TNF; TNFSF2; DIF; TNF-alpha
Study 6828617 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25559914 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25559914 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 21619917 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 16894950 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 29727013 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 14550817 — Surrogate Endpoint (SUR): Bone mineral density
Study 25831408 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 25335329 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 25335329 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 25335329 — Surrogate Endpoint (SUR): Bone mineral density
Study 30173089 — Predictive Biomarker (PRD): SPTB mRNA
Genes: SPTB; SPTB1
Study 18528794 — Surrogate Endpoint (SUR): Blood pressure
Study 16136931 — Surrogate Endpoint (SUR): Blood pressure
Study 15142864 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11355925 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 7949797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7949797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3148036 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27626242 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24670418 — Surrogate Endpoint (SUR): Blood pressure
Study 18786299 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8908384 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24928832 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11341486 — Surrogate Endpoint (SUR): Blood pressure
Study 30826774 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 26100253 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19847908 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 9771949 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31801395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30671976 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27780368 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21617168 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 8980952 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18946626 — Surrogate Endpoint (SUR): Bone mineral density
Study 15908335 — Predictive Biomarker (PRD): SOBP mRNA
Genes: SOBP; JXC1
Study 7552876 — Surrogate Endpoint (SUR): Blood pressure
Study 19534587 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 19534587 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 15375791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9726499 — Surrogate Endpoint (SUR): Blood pressure
Study 7859801 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7859801 — Surrogate Endpoint (SUR): Blood pressure
Study 2735626 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27289411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27289411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20484759 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20484759 — Surrogate Endpoint (SUR): Blood pressure
Study 2358837 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28272299 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 21586838 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1331558 — Surrogate Endpoint (SUR): Blood pressure
Study 26727506 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26727506 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26727506 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 26727506 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 22160483 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 22160483 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 1436129 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25292072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25292072 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23019943 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20110554 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14693180 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 26701796 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 26701796 — Surrogate Endpoint (SUR): Bone mineral density
Study 21502892 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 9356089 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26302900 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 18081357 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8201222 — Monitoring Biomarker (MOI): HBV DNA
Study 28754483 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 28754483 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 22585294 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20032493 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 11823078 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11823078 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28986203 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10777184 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 29570467 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21147707 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 18204158 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 15716689 — Surrogate Endpoint (SUR): Blood pressure
Study 29886499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28034693 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20533214 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15080373 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15080373 — Surrogate Endpoint (SUR): Blood pressure
Study 24061999 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 31227466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31227466 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31227466 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11696471 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11696471 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11696471 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2467116 — Surrogate Endpoint (SUR): Blood pressure
Study 27179830 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27179830 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21838789 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10493456 — Surrogate Endpoint (SUR): Bone mineral density
Study 10493456 — Surrogate Endpoint (SUR): Serum calcium
Study 1717782 — Surrogate Endpoint (SUR): Blood pressure
Study 6635104 — Surrogate Endpoint (SUR): Blood pressure
Study 30817466 — Surrogate Endpoint (SUR): Blood pressure
Study 25701337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25701337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30885800 — Predictive Biomarker (PRD): ST8SIA4 mRNA
Genes: ST8SIA4; PST; PST1; SIAT8D
Study 19647859 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 7706702 — Surrogate Endpoint (SUR): Blood pressure
Study 2689970 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 2689970 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 2689970 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 2689970 — Predictive Biomarker (PRD): TP53INP1 mRNA
Genes: TP53INP1; P53DINP1; SIP
Study 23550251 — Surrogate Endpoint (SUR): Blood pressure
Study 19928397 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 16700202 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29511994 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2442552 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2442552 — Surrogate Endpoint (SUR): Blood pressure
Study 27113628 — Surrogate Endpoint (SUR): Bone mineral density
Study 24845171 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1482268 — Surrogate Endpoint (SUR): Blood pressure
Study 24273568 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 24273568 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 24273568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 20693157 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15842142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15842142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15842142 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 15842142 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30295335 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 27022111 — Predictive Biomarker (PRD): Hormone receptor
Study 17631800 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17631800 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17631800 — Surrogate Endpoint (SUR): Blood pressure
Study 21179917 — Surrogate Endpoint (SUR): Blood pressure
Study 8534483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1810682 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1810682 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29507752 — Surrogate Endpoint (SUR): Blood pressure
Study 11196521 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 7916401 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25600221 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 25600221 — Surrogate Endpoint (SUR): Blood pressure
Study 15213896 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 16677162 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16677162 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9091555 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 7037661 — Surrogate Endpoint (SUR): Blood pressure
Study 30782917 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24903197 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 17301557 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30993344 — Safety Biomarker (SAF): Bacteroidetes phylum
Study 11061574 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 9352161 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 3709018 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29027324 — Pharmacodynamic Biomarker (PDY): miR-132
Genes: MIR132
Study 20442540 — Surrogate Endpoint (SUR): Serum creatinine
Study 12600228 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 12600228 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 12600228 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 1718369 — Surrogate Endpoint (SUR): Serum LDL cholesterol