TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28440046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28440046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28440046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28441111 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28441695 — Surrogate Endpoint (SUR): Blood pressure
Study 28442212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28445112 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28445112 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28445112 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 28445112 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 28445112 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 28445112 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 28445112 — Predictive Biomarker (PRD): FOXA1 mRNA
Genes: FOXA1; HNF3A; TCF3A
Study 28445112 — Predictive Biomarker (PRD): BCL11A mRNA
Genes: BCL11A; CTIP1; EVI9; KIAA1809; ZNF856
Study 28446495 — Surrogate Endpoint (SUR): Blood pressure
Study 28448562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28448562 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28448594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28448594 — Safety Biomarker (SAF): Human leucocyte antigen
Study 28448594 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 28448594 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 28448594 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 28449674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28449809 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 28449809 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 28450567 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 28450567 — Monitoring Biomarker (MOI): Cell-free DNA
Study 28453532 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 28453692 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28453697 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28453697 — Predictive Biomarker (PRD): Microsatellite instability
Study 28453704 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28453704 — Predictive Biomarker (PRD): GRB7 mRNA
Genes: GRB7
Study 28453702 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 28453773 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28454122 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 28454530 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28454530 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28454530 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28454531 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28454531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28455281 — Surrogate Endpoint (SUR): Blood pressure
Study 28458180 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 28460066 — Predictive Biomarker (PRD): FGF3 mRNA
Genes: FGF3; INT2
Study 28460066 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 28461298 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28464817 — Predictive Biomarker (PRD): MYOZ1 mRNA
Genes: MYOZ1; MYOZ
Study 28465125 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28466557 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 28466557 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 28468890 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 28470739 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 28470739 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 28471445 — Surrogate Endpoint (SUR): Bone mineral density
Study 28471765 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28472067 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28472366 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28472366 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 28472437 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 28472509 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 28472509 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 28472974 — Surrogate Endpoint (SUR): Blood pressure
Study 28473206 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28473406 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 28475704 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28476440 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 28476913 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28477848 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28479237 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28479237 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28480049 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28480334 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28481639 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28481639 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 28482007 — Predictive Biomarker (PRD): EGFL6 mRNA
Genes: EGFL6; MAEG; PP648; UNQ281/PRO320
Study 28482007 — Predictive Biomarker (PRD): FSTL3 mRNA
Genes: FSTL3; FLRG; UNQ674/PRO1308
Study 28482007 — Predictive Biomarker (PRD): CRYAB mRNA
Genes: CRYAB; CRYA2; HSPB5
Study 28482007 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 28482007 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 28482007 — Predictive Biomarker (PRD): USP53 mRNA
Genes: USP53; KIAA1350
Study 28482146 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 28483761 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 28484421 — Monitoring Biomarker (MOI): Procalcitonin
Study 28486646 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28486646 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28486646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28487034 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28487491 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 28487491 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 28489488 — Predictive Biomarker (PRD): RHOF mRNA
Genes: RHOF; ARHF; RIF
Study 28489510 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28490433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28493866 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 28494071 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 28494506 — Predictive Biomarker (PRD): AADAC mRNA
Genes: AADAC; DAC
Study 28494788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28494812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28495804 — Predictive Biomarker (PRD): SLMAP mRNA
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 28495896 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 28497070 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 28497757 — Surrogate Endpoint (SUR): Pathological complete response
Study 28498190 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28498618 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 28499389 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 28501139 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 28502892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28502892 — Monitoring Biomarker (MOI): Procalcitonin
Study 28503188 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28505327 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28505327 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 28505327 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 28506446 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study 28513244 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28514281 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 28514281 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28514773 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28515099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28515099 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28515269 — Predictive Biomarker (PRD): DSP mRNA
Genes: DSP
Study 28515791 — Surrogate Endpoint (SUR): Bone mineral density
Study 28521737 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 28521737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28521888 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 28522574 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 28522574 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 28522574 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 28525389 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 28525389 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 28525886 — Surrogate Endpoint (SUR): Blood pressure
Study 28526489 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28526489 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28528200 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 28528200 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 28528200 — Predictive Biomarker (PRD): NLRC4 mRNA
Genes: NLRC4; CARD12; CLAN; CLAN1; IPAF; UNQ6189/PRO20215
Study 28528200 — Predictive Biomarker (PRD): IL1RL1 mRNA
Genes: IL1RL1; DER4; ST2; T1
Study 28528767 — Surrogate Endpoint (SUR): Serum creatinine
Study 28528875 — Surrogate Endpoint (SUR): Blood pressure
Study 28531175 — Surrogate Endpoint (SUR): Serum creatinine
Study 28531309 — Surrogate Endpoint (SUR): Bone mineral density
Study 28533941 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 28533941 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28537061 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28538136 — Predictive Biomarker (PRD): ANGPTL3 mRNA
Genes: ANGPTL3; ANGPT5; UNQ153/PRO179
Study 28538136 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28542350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28545575 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28547918 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 28547918 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 28550039 — Surrogate Endpoint (SUR): Hematologic response
Study 28552512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28552987 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28554226 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 28554585 — Surrogate Endpoint (SUR): Serum creatinine
Study 28554936 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study 28559019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28560656 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 28566335 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 28567369 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 28567369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 11
Genes: CXCL11; ITAC; SCYB11; SCYB9B
Study 28567369 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 28567688 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 28570796 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 28571639 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28572079 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28575201 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28576398 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28577957 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28578664 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 28578691 — Surrogate Endpoint (SUR): Blood pressure
Study 28578705 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 28579823 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 28580793 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28580793 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 28583305 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 28583617 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28587613 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28587667 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28589492 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 28592297 — Surrogate Endpoint (SUR): Serum creatinine
Study 28592319 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 28592319 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28592434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28592572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28592616 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28592615 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 28593789 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28594442 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 28594711 — Surrogate Endpoint (SUR): Blood pressure
Study 28595189 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28596770 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 28598206 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28600132 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 28601826 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 28602520 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28602520 — Predictive Biomarker (PRD): RIT1 mRNA
Genes: RIT1; RIBB; RIT; ROC1
Study 28602585 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 28602585 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 28602585 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 28603514 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study 28606598 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28606966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28607686 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28607686 — Surrogate Endpoint (SUR): Blood pressure
Study 28611125 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 28613220 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28614154 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28614791 — Predictive Biomarker (PRD): ACKR1 mRNA
Genes: ACKR1; DARC; FY; GPD
Study 28614995 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 28615304 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 28616291 — Surrogate Endpoint (SUR): Blood pressure
Study 28617144 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28619014 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28619014 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28619117 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 28619117 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 28620382 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28620471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28620471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28620471 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 28622454 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28623902 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28624608 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 28625503 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28625629 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28625629 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28625777 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28625834 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28626781 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28629333 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 28629333 — Predictive Biomarker (PRD): PSMB7 mRNA
Genes: PSMB7; Z
Study 28630120 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 28631283 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 28633365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 28633425 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28633425 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 28636901 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28637738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28640364 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28640364 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28644056 — Predictive Biomarker (PRD): ZMYM2 mRNA
Genes: ZMYM2; FIM; RAMP; ZNF198
Study 28645324 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 28645776 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 28645867 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28645867 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 28645867 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 28648122 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 28648475 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28649644 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28651368 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 28651368 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 28653250 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28655452 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28657941 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28657941 — Predictive Biomarker (PRD): Hormone receptor
Study 28658601 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 28658601 — Surrogate Endpoint (SUR): Bone mineral density
Study 28662235 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 28662235 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 28664507 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28664507 — Predictive Biomarker (PRD): Hormone receptor
Study 28664507 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 28666281 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 28666775 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 28666990 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 28667569 — Surrogate Endpoint (SUR): Blood pressure