TrialPanorama/TrialPanorama-database huggingface dataset:
Study 18210334 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18210334 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15492949 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15492949 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15492949 — Surrogate Endpoint (SUR): Serum creatinine
Study 9444298 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20350955 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 21385882 — Surrogate Endpoint (SUR): Pathological complete response
Study 21385882 — Predictive Biomarker (PRD): Hormone receptor
Study 18317605 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 25801891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25801891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10200896 — Surrogate Endpoint (SUR): Blood pressure
Study 26818913 — Surrogate Endpoint (SUR): Blood pressure
Study 24634346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16297755 — Surrogate Endpoint (SUR): Blood pressure
Study 11932297 — Surrogate Endpoint (SUR): Blood pressure
Study 30573480 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30573480 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 30573480 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16492915 — Predictive Biomarker (PRD): MUC13 mRNA
Genes: MUC13; DRCC1; RECC; UNQ6194/PRO20221
Study 16492915 — Predictive Biomarker (PRD): S100A10 mRNA
Genes: S100A10; ANX2LG; CAL1L; CLP11
Study 16492915 — Safety Biomarker (SAF): Fatty acid binding protein 1
Genes: FABP1; FABPL
Study 12646971 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12646971 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10883413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16641265 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16641265 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16641265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14703955 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14703955 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 1335006 — Surrogate Endpoint (SUR): Blood pressure
Study 6373586 — Surrogate Endpoint (SUR): Blood pressure
Study 30075578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30075578 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22992307 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 6863097 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15692973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15692973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10509953 — Surrogate Endpoint (SUR): Serum uric acid
Study 10509953 — Surrogate Endpoint (SUR): Serum creatinine
Study 1777377 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1777377 — Surrogate Endpoint (SUR): Blood pressure
Study 30405296 — Predictive Biomarker (PRD): FOXP3
Genes: JM2; XPID; AIID; PIDX; DIETER; SCURFIN
Study 30405296 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 30405296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30405296 — Safety Biomarker (SAF): MTHFR
Study 20226447 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MMP10 mRNA
Genes: MMP10; STMY2
Study 20226447 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 20226447 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20226447 — Predictive Biomarker (PRD): ITGA3 mRNA
Genes: ITGA3; MSK18
Study 20226447 — Predictive Biomarker (PRD): ITGA5 mRNA
Genes: ITGA5; FNRA
Study 20226447 — Predictive Biomarker (PRD): ITGB3 mRNA
Genes: ITGB3; GP3A
Study 20226447 — Predictive Biomarker (PRD): ITGB4 mRNA
Genes: ITGB4
Study 20226447 — Predictive Biomarker (PRD): LAMB3 mRNA
Genes: LAMB3; LAMNB1
Study 8041539 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 27517654 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 24386859 — Predictive Biomarker (PRD): HOXA13 mRNA
Genes: HOXA13; HOX1J
Study 19802508 — Surrogate Endpoint (SUR): Bone mineral density
Study 18156455 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 18156455 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 15716709 — Surrogate Endpoint (SUR): Blood pressure
Study 21236344 — Surrogate Endpoint (SUR): Bone mineral density
Study 15456093 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11466986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3676211 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20962212 — Safety Biomarker (SAF): Interleukin 1
Study 8843528 — Surrogate Endpoint (SUR): Blood pressure
Study 6331482 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6331482 — Surrogate Endpoint (SUR): Blood pressure
Study 23848030 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23848030 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23848030 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9028644 — Surrogate Endpoint (SUR): Blood pressure
Study 30099422 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 22423133 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20441717 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15828904 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 15828904 — Surrogate Endpoint (SUR): Serum calcium
Study 12478069 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12478069 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 7775627 — Surrogate Endpoint (SUR): Blood pressure
Study 35406 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 29982544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12126264 — Surrogate Endpoint (SUR): Blood pressure
Study 7418949 — Surrogate Endpoint (SUR): Blood pressure
Study 24916884 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 11491418 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23612508 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21375545 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19596415 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28603046 — Predictive Biomarker (PRD): EIF2AK3 mRNA
Genes: EIF2AK3; PEK; PERK
Study 28603046 — Predictive Biomarker (PRD): HSPA5 mRNA
Genes: HSPA5; GRP78
Study 28603046 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 19487905 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16469156 — Safety Biomarker (SAF): Bacterial beta-glucuronidase
Genes: uidA; gurA; gusA; b1617; JW1609
Study 8501340 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21885490 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 16936208 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 9360512 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 9360512 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 9360512 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9360512 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 3834842 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22461445 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 22461445 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22461445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30106328 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 23183751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21721475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12898201 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 11023459 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9182469 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1587067 — Surrogate Endpoint (SUR): Blood pressure
Study 3886400 — Surrogate Endpoint (SUR): Blood pressure
Study 10376483 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10376483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10376483 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31633158 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 31633158 — Predictive Biomarker (PRD): CYP21A2 mRNA
Genes: CYP21A2; CYP21; CYP21B
Study 27118812 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27118812 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 24557088 — Predictive Biomarker (PRD): GABRA2 mRNA
Genes: GABRA2
Study 10082242 — Predictive Biomarker (PRD): PTK7 mRNA
Genes: PTK7; CCK4
Study 27667464 — Predictive Biomarker (PRD): SOCS1 mRNA
Genes: SOCS1; SSI1; TIP3
Study 27667464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27667464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27667464 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 27667464 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24797938 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 24797938 — Predictive Biomarker (PRD): ATG5 mRNA
Genes: ATG5; APG5L; ASP
Study 24797938 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 24797938 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 22569857 — Safety Biomarker (SAF): Hyaluronic acid
Study 24020899 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11564829 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24930619 — Surrogate Endpoint (SUR): Blood pressure
Study 23444220 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21601481 — Surrogate Endpoint (SUR): Blood pressure
Study 11565517 — Surrogate Endpoint (SUR): Blood pressure
Study 11565517 — Surrogate Endpoint (SUR): Serum creatinine
Study 3327677 — Surrogate Endpoint (SUR): Blood pressure
Study 22709990 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18061415 — Surrogate Endpoint (SUR): Blood pressure
Study 9103485 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 7942523 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29196928 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29196928 — Surrogate Endpoint (SUR): Serum creatinine
Study 23125290 — Surrogate Endpoint (SUR): Bone mineral density
Study 9203174 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28060012 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25103870 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29788732 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 23460714 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23460714 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 23460714 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25632806 — Surrogate Endpoint (SUR): Blood pressure
Study 7030978 — Surrogate Endpoint (SUR): Blood pressure
Study 31704050 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 31704050 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 31704050 — Surrogate Endpoint (SUR): Serum calcium
Study 30247967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18230694 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18230694 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 15163387 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 15163387 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study 27231549 — Surrogate Endpoint (SUR): Serum creatinine
Study 12095381 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7671566 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2111414 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 31415003 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11004863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9486935 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9486935 — Surrogate Endpoint (SUR): Serum creatinine
Study 9486935 — Surrogate Endpoint (SUR): Blood pressure
Study 19501213 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 19501213 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23563111 — Surrogate Endpoint (SUR): Bone mineral density
Study 14714769 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 14714769 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30922373 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23416033 — Surrogate Endpoint (SUR): Blood pressure
Study 17497591 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 11441422 — Surrogate Endpoint (SUR): Blood pressure
Study 2252243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30839302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11711508 — Surrogate Endpoint (SUR): Blood pressure
Study 28766132 — Predictive Biomarker (PRD): NCOA3 mRNA
Genes: NCOA3; AIB1; BHLHE42; RAC3; TRAM1
Study 28766132 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28766132 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12600850 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 11268452 — Surrogate Endpoint (SUR): Serum creatinine
Study 6397652 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 26946613 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26946613 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15115904 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12239447 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9846584 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 8960727 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 18568800 — Surrogate Endpoint (SUR): Blood pressure
Study 30126559 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24448173 — Surrogate Endpoint (SUR): Serum uric acid
Study 30889096 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17452677 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17452677 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 10440909 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 10440909 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 10440909 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 10440909 — Predictive Biomarker (PRD): PPIC mRNA
Genes: PPIC; CYPC
Study 10440909 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 10440909 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31774842 — Surrogate Endpoint (SUR): Blood pressure
Study 19905943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19905943 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19905943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2184002 — Surrogate Endpoint (SUR): Blood pressure
Study 31670008 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31670008 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 31670008 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 28356431 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19911216 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8154629 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26780085 — Predictive Biomarker (PRD): DKK1 mRNA
Genes: DKK1; UNQ492/PRO1008
Study 26780085 — Surrogate Endpoint (SUR): Bone mineral density
Study 22563948 — Surrogate Endpoint (SUR): Blood pressure
Study 27825388 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 27825388 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9527747 — Predictive Biomarker (PRD): SH2D1A mRNA
Genes: SH2D1A; DSHP; SAP
Study 9527747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9527747 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25835438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19423109 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19423109 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 19423109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17969367 — Surrogate Endpoint (SUR): Blood pressure
Study 11477813 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 7865804 — Predictive Biomarker (PRD): HBE1 mRNA
Genes: HBE1; HBE
Study 27678433 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16075063 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12461037 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10656205 — Surrogate Endpoint (SUR): Bone mineral density
Study 6685597 — Surrogate Endpoint (SUR): Blood pressure
Study 29066122 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 26935286 — Surrogate Endpoint (SUR): Blood pressure
Study 26645514 — Predictive Biomarker (PRD): EDAR mRNA
Genes: EDAR; DL
Study 18243724 — Surrogate Endpoint (SUR): Serum creatinine
Study 6805243 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23880826 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 23880826 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23880826 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19659999 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 19659999 — Predictive Biomarker (PRD): ADRB3 mRNA
Genes: ADRB3; ADRB3R; B3AR
Study 19659999 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2109497 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2109497 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16150195 — Surrogate Endpoint (SUR): Bone mineral density
Study 28139220 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 31888751 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 26833642 — Surrogate Endpoint (SUR): Blood pressure
Study 26833642 — Surrogate Endpoint (SUR): Serum potassium
Study 25191896 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 21429799 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21429799 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21429799 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21429799 — Predictive Biomarker (PRD): Hormone receptor
Study 15264729 — Surrogate Endpoint (SUR): Blood pressure
Study 2108981 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 27428294 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27428294 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 24460655 — Predictive Biomarker (PRD): Liver iron
Study 14700505 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 28041917 — Predictive Biomarker (PRD): MCCC2 mRNA
Genes: MCCC2; MCCB
Study 16618976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16618976 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8339411 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29723578 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 26597128 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 9175147 — Surrogate Endpoint (SUR): Blood pressure
Study 8465780 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol