TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11043855 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11043855 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11043855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11043855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11043855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8129540 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8129540 — Surrogate Endpoint (SUR): Blood pressure
Study 7852918 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27525386 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 27525386 — Predictive Biomarker (PRD): HRAS mRNA
Genes: HRAS; HRAS1
Study 27525386 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27525386 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 20705558 — Predictive Biomarker (PRD): Hormone receptor
Study 15985482 — Predictive Biomarker (PRD): PLIN1 mRNA
Genes: PLIN1; PERI; PLIN
Study 2458159 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22128442 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17493196 — Surrogate Endpoint (SUR): Bone mineral density
Study 7639104 — Surrogate Endpoint (SUR): Bone mineral density
Study 2560289 — Surrogate Endpoint (SUR): Blood pressure
Study 30840024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30840024 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29044000 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26512456 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26512456 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23798006 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9648703 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 30803706 — Surrogate Endpoint (SUR): Blood pressure
Study 25140597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9420339 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 23579517 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 23579517 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15229100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9244941 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 23834653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23834653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23834653 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15663681 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30641005 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24378144 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 9551739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30986442 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30672249 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11035135 — Surrogate Endpoint (SUR): Blood pressure
Study 9385122 — Surrogate Endpoint (SUR): Bone mineral density
Study 9385122 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9385122 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30895697 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 30895697 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16430566 — Surrogate Endpoint (SUR): Blood pressure
Study 14679434 — Surrogate Endpoint (SUR): Bone mineral density
Study 18382126 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 15819586 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 21871427 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 8877126 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23701917 — Safety Biomarker (SAF): CREM mRNA
Genes: CREM
Study 21986180 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 10512253 — Surrogate Endpoint (SUR): Blood pressure
Study 29864379 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17611335 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17611335 — Surrogate Endpoint (SUR): Blood pressure
Study 12152252 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19636603 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 19636603 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 19636603 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 29754829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29754829 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25942015 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20587350 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 20587350 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 18261569 — Surrogate Endpoint (SUR): Serum creatinine
Study 1355149 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21890591 — Safety Biomarker (SAF): DRD2
Study 17386348 — Surrogate Endpoint (SUR): Blood pressure
Study 11431653 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2690316 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 2690316 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9589675 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9589675 — Safety Biomarker (SAF): Connecting peptide
Genes: AHSG; FETUA; PRO2743
Study 7604796 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7604796 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19470469 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 9718191 — Surrogate Endpoint (SUR): Serum calcium
Study 17108815 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 17108815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17108815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31959167 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27786516 — Predictive Biomarker (PRD): HYLS1 mRNA
Genes: HYLS1; HLS
Study 22575081 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1726003 — Surrogate Endpoint (SUR): Blood pressure
Study 26758677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21182350 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18353886 — Predictive Biomarker (PRD): IL1R1 mRNA
Genes: IL1R1; IL1R; IL1RA; IL1RT1
Study 18353886 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 18353886 — Predictive Biomarker (PRD): CEBPD mRNA
Genes: CEBPD
Study 18353886 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 1593511 — Surrogate Endpoint (SUR): Blood pressure
Study 23134888 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23134888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19195454 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12215586 — Predictive Biomarker (PRD): COL3A1 mRNA
Genes: COL3A1
Study 10563066 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10563066 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29230663 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27222508 — Predictive Biomarker (PRD): ABCC8 mRNA
Genes: ABCC8; HRINS; SUR; SUR1
Study 25234339 — Surrogate Endpoint (SUR): Blood pressure
Study 11807358 — Safety Biomarker (SAF): Hyaluronic acid
Study 10450295 — Surrogate Endpoint (SUR): Blood pressure
Study 19000540 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 19000540 — Surrogate Endpoint (SUR): Serum calcium
Study 15940616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28109729 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 19340550 — Surrogate Endpoint (SUR): Blood pressure
Study 23754735 — Safety Biomarker (SAF): DRD2
Study 21788353 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 29805981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27823695 — Surrogate Endpoint (SUR): Blood pressure
Study 25015176 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 17112855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17112855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17112855 — Safety Biomarker (SAF): IL-6 and IL-10
Study 27327779 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 19943060 — Surrogate Endpoint (SUR): Blood pressure
Study 23661337 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23661337 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23661337 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11177119 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9394322 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 10958177 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22704860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18782657 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18782657 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15111373 — Surrogate Endpoint (SUR): Bone mineral density
Study 15111373 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15111373 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3203661 — Surrogate Endpoint (SUR): Blood pressure
Study 26214772 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 26214772 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 14641992 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16115830 — Surrogate Endpoint (SUR): Blood pressure
Study 2261943 — Surrogate Endpoint (SUR): Blood pressure
Study 2207419 — Surrogate Endpoint (SUR): Blood pressure
Study 24857519 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 17109595 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8988939 — Surrogate Endpoint (SUR): Blood pressure
Study 29776990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29776990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29776990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25338053 — Surrogate Endpoint (SUR): Blood pressure
Study 20723651 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10450290 — Surrogate Endpoint (SUR): Blood pressure
Study 6261677 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 25381300 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 22541738 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 17850560 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12372131 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29183574 — Safety Biomarker (SAF): Interleukin 1
Study 26374297 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 26374297 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 26374297 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26374297 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 26374297 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26374297 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19110026 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19110026 — Safety Biomarker (SAF): BDNF
Study 29114907 — Surrogate Endpoint (SUR): Bone mineral density
Study 27296360 — Surrogate Endpoint (SUR): Blood pressure
Study 27325795 — Surrogate Endpoint (SUR): Serum calcium
Study 25294886 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 17826777 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 25680887 — Surrogate Endpoint (SUR): Blood pressure
Study 25680887 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28351060 — Surrogate Endpoint (SUR): Blood pressure
Study 8287317 — Surrogate Endpoint (SUR): Bone mineral density
Study 25079365 — Safety Biomarker (SAF): Interleukin 1
Study 25079365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21710402 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 21710402 — Surrogate Endpoint (SUR): Blood pressure
Study 15144688 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 15144688 — Surrogate Endpoint (SUR): Bone mineral density
Study 8401150 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 30921804 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16504691 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 9313603 — Surrogate Endpoint (SUR): Blood pressure
Study 8383396 — Surrogate Endpoint (SUR): Blood pressure
Study 3536151 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31591117 — Surrogate Endpoint (SUR): Serum creatinine
Study 19086814 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7503087 — Surrogate Endpoint (SUR): Bone mineral density
Study 7503087 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 30117365 — Safety Biomarker (SAF): Cytochrome c
Study 25138127 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 19783715 — Surrogate Endpoint (SUR): Blood pressure
Study 2666249 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 20143531 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14967062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1833301 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 1833301 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 1833301 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 28174353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24293094 — Surrogate Endpoint (SUR): Bone mineral density
Study 22854880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22854880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18634706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18634706 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18634706 — Surrogate Endpoint (SUR): Blood pressure
Study 17961422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9824387 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 23666460 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21857144 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 28838263 — Predictive Biomarker (PRD): GSTK1 mRNA
Genes: GSTK1; HDCMD47P
Study 28838263 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 28838263 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 28838263 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 18823395 — Surrogate Endpoint (SUR): Bone mineral density
Study 12563567 — Surrogate Endpoint (SUR): Blood pressure
Study 2643865 — Surrogate Endpoint (SUR): Blood pressure
Study 27358638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27358638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27358638 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 27358638 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27358638 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7662752 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7662752 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 19684472 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 14681846 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 9833177 — Surrogate Endpoint (SUR): Blood pressure
Study 16505046 — Surrogate Endpoint (SUR): Blood pressure
Study 15599834 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9062618 — Surrogate Endpoint (SUR): Blood pressure
Study 29266290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 29266290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 27130705 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24012684 — Surrogate Endpoint (SUR): Blood pressure
Study 23406818 — Surrogate Endpoint (SUR): Blood pressure
Study 1324011 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6734705 — Surrogate Endpoint (SUR): Serum creatinine
Study 30957673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22891782 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 22891782 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22891782 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25803626 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 19784816 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15198784 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11465516 — Surrogate Endpoint (SUR): Serum testosterone
Study 25528430 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 25528430 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 19217460 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17313292 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 11593094 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11593094 — Surrogate Endpoint (SUR): Blood pressure
Study 28517955 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9523210 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 7907073 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29042358 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 22445501 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22445501 — Safety Biomarker (SAF): Interleukin 1
Study 22445501 — Safety Biomarker (SAF): IL-6 and IL-10
Study 28681387 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26373676 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 26373676 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 26373676 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study 28864749 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 28864749 — Surrogate Endpoint (SUR): Serum creatinine
Study 16322487 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study 23277897 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21593294 — Surrogate Endpoint (SUR): Blood pressure
Study 19879995 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 15521842 — Surrogate Endpoint (SUR): Bone mineral density
Study 9331018 — Surrogate Endpoint (SUR): Blood pressure
Study 6383654 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26817502 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 26817502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23257132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23257132 — Surrogate Endpoint (SUR): Bone mineral density
Study 10432323 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27785095 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF