TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22435835 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22435835 — Surrogate Endpoint (SUR): Blood pressure
Study 17884359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8950071 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8950071 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28316174 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24379072 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 14747225 — Surrogate Endpoint (SUR): Blood pressure
Study 31013550 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 31013550 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 26450601 — Surrogate Endpoint (SUR): Blood pressure
Study 26450601 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19348600 — Surrogate Endpoint (SUR): Blood pressure
Study 11565669 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3074299 — Surrogate Endpoint (SUR): Blood pressure
Study 26725385 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31329901 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 31329901 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24604886 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 15865226 — Monitoring Biomarker (MOI): HBV DNA
Study 9651635 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 31103412 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31103412 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 3089467 — Safety Biomarker (SAF): 51Cr-EDTA
Study 15916998 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15916998 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 15916998 — Surrogate Endpoint (SUR): Blood pressure
Study 29932518 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 19915736 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 6528617 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31377477 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31377477 — Predictive Biomarker (PRD): Hormone receptor
Study 19833273 — Surrogate Endpoint (SUR): Blood pressure
Study 10595814 — Safety Biomarker (SAF): Human leucocyte antigen
Study 10595814 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29094998 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 21906521 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21906521 — Surrogate Endpoint (SUR): Serum testosterone
Study 17584010 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16139813 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 3890049 — Surrogate Endpoint (SUR): Blood pressure
Study 22686944 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7618647 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 30214066 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 19960001 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 19960001 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 28697780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16222900 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16222900 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25942482 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21505361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19740297 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16782975 — Surrogate Endpoint (SUR): Blood pressure
Study 8833208 — Surrogate Endpoint (SUR): Bone mineral density
Study 26024293 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17668564 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15189781 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15189781 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11349017 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31873788 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29664983 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29664983 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19082803 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19082803 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10862636 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2862223 — Predictive Biomarker (PRD): Hormone receptor
Study 27146650 — Surrogate Endpoint (SUR): Blood pressure
Study 15936184 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9094892 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3541168 — Surrogate Endpoint (SUR): Blood pressure
Study 30134847 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 27780198 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 24285284 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 10430720 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 6381007 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24709780 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24709780 — Surrogate Endpoint (SUR): Blood pressure
Study 22450429 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20055981 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 18076334 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 12566175 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8820894 — Surrogate Endpoint (SUR): Plasma ammonia
Study 29331036 — Predictive Biomarker (PRD): PDCD4 mRNA
Genes: PDCD4; H731
Study 29331036 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 19004194 — Surrogate Endpoint (SUR): Blood pressure
Study 14520257 — Surrogate Endpoint (SUR): Bone mineral density
Study 8699239 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 9531580 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9531580 — Surrogate Endpoint (SUR): Hematologic response
Study 11780205 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11780205 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11780205 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2859781 — Surrogate Endpoint (SUR): Blood pressure
Study 2859781 — Surrogate Endpoint (SUR): Serum potassium
Study 12351376 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 10445679 — Surrogate Endpoint (SUR): Blood pressure
Study 19141125 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 19141125 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3251497 — Surrogate Endpoint (SUR): Blood pressure
Study 23168523 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21148051 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 21148051 — Surrogate Endpoint (SUR): Blood pressure
Study 10661003 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 10661003 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 16864926 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12888781 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 9196381 — Surrogate Endpoint (SUR): Blood pressure
Study 3085612 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 23098865 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19443519 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15349002 — Surrogate Endpoint (SUR): Blood pressure
Study 11739135 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12529662 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8690109 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 17152744 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26179619 — Surrogate Endpoint (SUR): Blood pressure
Study 8733040 — Surrogate Endpoint (SUR): Blood pressure
Study 1684991 — Surrogate Endpoint (SUR): Blood pressure
Study 31056710 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 30280326 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 21551082 — Predictive Biomarker (PRD): AACS mRNA
Genes: AACS; ACSF1
Study 21551082 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 7595911 — Surrogate Endpoint (SUR): Blood pressure
Study 7595911 — Surrogate Endpoint (SUR): Serum potassium
Study 30837600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26767505 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23059199 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19570887 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 15570025 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2448408 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 28677237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 18224269 — Surrogate Endpoint (SUR): Bone mineral density
Study 10646156 — Surrogate Endpoint (SUR): Blood pressure
Study 9015118 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29516771 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 17919551 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17919551 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17919551 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15565083 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15565083 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10806662 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 179286 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18687253 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15903373 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12877794 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6501718 — Surrogate Endpoint (SUR): Blood pressure
Study 16223581 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10453931 — Monitoring Biomarker (MOI): HBV DNA
Study 7605354 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 7605354 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2447151 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 29543138 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29543138 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26752621 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 25185277 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20795819 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16356429 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11571605 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 28827229 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22013492 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 6357930 — Surrogate Endpoint (SUR): Blood pressure
Study 27107325 — Predictive Biomarker (PRD): Hormone receptor
Study 21733056 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 21733056 — Surrogate Endpoint (SUR): Blood pressure
Study 17686670 — Surrogate Endpoint (SUR): Bone mineral density
Study 15076221 — Surrogate Endpoint (SUR): Blood pressure
Study 9402540 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 2783076 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23432209 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 23432209 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 19798037 — Surrogate Endpoint (SUR): Blood pressure
Study 11776280 — Safety Biomarker (SAF): Interleukin 1
Study 10155593 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27806235 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 12730556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25253016 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17449506 — Surrogate Endpoint (SUR): Blood pressure
Study 23866300 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23866300 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16928196 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16928196 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15116057 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15136070 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15136070 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29218680 — Surrogate Endpoint (SUR): Blood pressure
Study 26307133 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 26307133 — Predictive Biomarker (PRD): CCND1 mRNA
Genes: CCND1; BCL1; PRAD1
Study 26307133 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26307133 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24481213 — Surrogate Endpoint (SUR): Blood pressure
Study 16076867 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 16076867 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 16076867 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 16076867 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 7027890 — Surrogate Endpoint (SUR): Blood pressure
Study 31553438 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31553438 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19243721 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 26243363 — Surrogate Endpoint (SUR): Bone mineral density
Study 17635940 — Predictive Biomarker (PRD): KISS1R mRNA
Genes: KISS1R; AXOR12; GPR54
Study 30305657 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 26739013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26739013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26739013 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26739013 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 26739013 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 12217597 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12217597 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28338206 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28338206 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25985708 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16014883 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12409984 — Surrogate Endpoint (SUR): Blood pressure
Study 31399275 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17073835 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 29456238 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29456238 — Surrogate Endpoint (SUR): Serum creatinine
Study 22072742 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15903123 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26039949 — Surrogate Endpoint (SUR): Blood pressure
Study 10909485 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 31881952 — Surrogate Endpoint (SUR): Blood pressure
Study 28373244 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21999406 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19084425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19084425 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15734089 — Surrogate Endpoint (SUR): Serum testosterone
Study 2405556 — Surrogate Endpoint (SUR): Blood pressure
Study 21681227 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 9472909 — Surrogate Endpoint (SUR): Blood pressure
Study 30695650 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30695650 — Predictive Biomarker (PRD): KMT2D mRNA
Genes: KMT2D; ALR; MLL2; MLL4
Study 25307295 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19384841 — Surrogate Endpoint (SUR): Blood pressure
Study 11865378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11865378 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20056803 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 12570928 — Surrogate Endpoint (SUR): Blood pressure
Study 8754408 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 8754408 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6342928 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 9817168 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2525351 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14155158 — Surrogate Endpoint (SUR): Blood pressure
Study 31013499 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 24180001 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24180001 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 19336732 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 15357562 — Surrogate Endpoint (SUR): Blood pressure
Study 11128861 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 11128861 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24249700 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18005804 — Surrogate Endpoint (SUR): Blood pressure
Study 6785100 — Surrogate Endpoint (SUR): Blood pressure
Study 23402476 — Surrogate Endpoint (SUR): Blood pressure
Study 7027891 — Surrogate Endpoint (SUR): Blood pressure
Study 21625252 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 21625252 — Safety Biomarker (SAF): CDA
Genes: CDD
Study 17984409 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 29945625 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 29945625 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 24075613 — Safety Biomarker (SAF): Hyaluronic acid
Study 21438778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21438778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21438778 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8952816 — Predictive Biomarker (PRD): AHSP mRNA
Genes: AHSP; EDRF; ERAF
Study 28388647 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28388647 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 28388647 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 25609006 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24228532 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24228532 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10760191 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 8633378 — Surrogate Endpoint (SUR): Bone mineral density
Study 22716204 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22716204 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 31349876 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 16001776 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12010228 — Surrogate Endpoint (SUR): Serum sodium
Study 7789044 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7789044 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6236952 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 6236952 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 6236952 — Predictive Biomarker (PRD): SERPINA7 mRNA
Genes: SERPINA7; TBG
Study 6236952 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 23836299 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 17889126 — Surrogate Endpoint (SUR): Serum creatinine
Study 12153599 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12153599 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 154748 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15047458 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11380284 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 11380284 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 11380284 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 2894215 — Surrogate Endpoint (SUR): Blood pressure
Study 18677023 — Surrogate Endpoint (SUR): Blood pressure
Study 19080533 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15680826 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27919633 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 26391700 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 11881062 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11881062 — Surrogate Endpoint (SUR): Blood pressure
Study 25770704 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein