TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19039596 — Predictive Biomarker (PRD): PDPR mRNA
Genes: PDPR; KIAA1990
Study 17503885 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12373268 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26761561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19910566 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 19910566 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19910566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19910566 — Safety Biomarker (SAF): Hyaluronic acid
Study 19910566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19910566 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19910566 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19910566 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 15515332 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 29578097 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18364502 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16293958 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12749746 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7744141 — Surrogate Endpoint (SUR): Serum testosterone
Study 25592552 — Safety Biomarker (SAF): RFC1
Genes: A1; PO-GA; RFC140; MHCBFB
Study 9474311 — Surrogate Endpoint (SUR): Blood pressure
Study 7940435 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 25622729 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 25622729 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23052930 — Surrogate Endpoint (SUR): Bone mineral density
Study 18223611 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1279279 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1279279 — Surrogate Endpoint (SUR): Blood pressure
Study 22333698 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 18319360 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18319360 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 18319360 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 11990003 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7477168 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7444552 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26997243 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 18033754 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 18033754 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 27825616 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 26397228 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10971248 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12676074 — Surrogate Endpoint (SUR): Blood pressure
Study 1829372 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1829372 — Surrogate Endpoint (SUR): Blood pressure
Study 29880047 — Predictive Biomarker (PRD): PRKRA mRNA
Genes: PRKRA; PACT; RAX; HSD-14; HSD14
Study 27253829 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11329231 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11329231 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9291302 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11555165 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22549090 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22549090 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 19733353 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 30043183 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 30043183 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 30043183 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 30043183 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25198268 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21148614 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29505867 — Surrogate Endpoint (SUR): Blood pressure
Study 12384647 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27630504 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23249098 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 11914244 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 2605801 — Surrogate Endpoint (SUR): Blood pressure
Study 26047470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18390917 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17342002 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28800067 — Surrogate Endpoint (SUR): Blood pressure
Study 23243212 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8738724 — Monitoring Biomarker (MOI): HBV DNA
Study 12849808 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 28674348 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21535498 — Predictive Biomarker (PRD): SDC1 mRNA
Genes: SDC1; SDC
Study 17606812 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 2864073 — Surrogate Endpoint (SUR): Blood pressure
Study 31391682 — Surrogate Endpoint (SUR): Blood pressure
Study 21599820 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 18843436 — Surrogate Endpoint (SUR): Bone mineral density
Study 7942575 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 29200983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25689594 — Surrogate Endpoint (SUR): Blood pressure
Study 30091135 — Surrogate Endpoint (SUR): Blood pressure
Study 20199265 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 16490430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16490430 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 16490430 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20808333 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16236854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16236854 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 14601482 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9925124 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28330794 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 16231754 — Surrogate Endpoint (SUR): Blood pressure
Study 12228843 — Surrogate Endpoint (SUR): Blood pressure
Study 8527710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8527710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24284498 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24284498 — Surrogate Endpoint (SUR): Blood pressure
Study 10574640 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 10574640 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30590387 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11322052 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 3115445 — Surrogate Endpoint (SUR): Blood pressure
Study 30510080 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 30510080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 27849563 — Surrogate Endpoint (SUR): Blood pressure
Study 23777763 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23777763 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 11726440 — Surrogate Endpoint (SUR): Blood pressure
Study 24553365 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22562977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7841754 — Predictive Biomarker (PRD): FYN mRNA
Genes: FYN
Study 7841754 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 7841754 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 7841754 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10757621 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 15665146 — Surrogate Endpoint (SUR): Blood pressure
Study 7852539 — Surrogate Endpoint (SUR): Blood pressure
Study 2182170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26712981 — Surrogate Endpoint (SUR): Blood pressure
Study 15355745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15355745 — Safety Biomarker (SAF): Interleukin 1
Study 8033771 — Surrogate Endpoint (SUR): Serum uric acid
Study 8033771 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22014807 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22014807 — Surrogate Endpoint (SUR): Bone mineral density
Study 19151449 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19151449 — Surrogate Endpoint (SUR): Blood pressure
Study 28643374 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 28643374 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21272186 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 7702198 — Surrogate Endpoint (SUR): Blood pressure
Study 19661447 — Surrogate Endpoint (SUR): Blood pressure
Study 18835927 — Surrogate Endpoint (SUR): Blood pressure
Study 17973988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9683389 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28173786 — Surrogate Endpoint (SUR): Blood pressure
Study 25782429 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 17878479 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17878479 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8461475 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22799753 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 14508234 — Surrogate Endpoint (SUR): Blood pressure
Study 10834421 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 11308250 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27805273 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 14691440 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17190951 — Predictive Biomarker (PRD): CDIP1 mRNA
Genes: CDIP1; C16orf5; CDIP; LITAFL
Study 9231885 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9231885 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 3074300 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3074300 — Surrogate Endpoint (SUR): Blood pressure
Study 31627907 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 31345792 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31345792 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26266385 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 1307517 — Predictive Biomarker (PRD): SFPQ mRNA
Genes: SFPQ; PSF
Study 3834227 — Safety Biomarker (SAF): Reactive oxygen species
Study 17702126 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12188443 — Surrogate Endpoint (SUR): Serum uric acid
Study 12188443 — Surrogate Endpoint (SUR): Serum creatinine
Study 24099724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24099724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24099724 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18833115 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 15684256 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 7597269 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 25472578 — Surrogate Endpoint (SUR): Blood pressure
Study 19409095 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15170922 — Safety Biomarker (SAF): Interleukin 1
Study 1975426 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28734705 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 21784403 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8454808 — Surrogate Endpoint (SUR): Blood pressure
Study 3022785 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 24141036 — Surrogate Endpoint (SUR): Bone mineral density
Study 22301925 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10555025 — Surrogate Endpoint (SUR): Bone mineral density
Study 22848508 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 22848508 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 22848508 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 30868576 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30868576 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11677930 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25530341 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 23873291 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 14573329 — Surrogate Endpoint (SUR): Blood pressure
Study 30584459 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27662495 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 18359648 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 6143505 — Surrogate Endpoint (SUR): Blood pressure
Study 27687032 — Safety Biomarker (SAF): DRD2
Study 10421228 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22794223 — Predictive Biomarker (PRD): KCNN3 mRNA
Genes: KCNN3; K3
Study 20700793 — Predictive Biomarker (PRD): CTSD mRNA
Genes: CTSD; CPSD
Study 19203070 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19203070 — Surrogate Endpoint (SUR): Blood pressure
Study 19203070 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 15708700 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15708700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2030065 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 12074178 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 12074178 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 2556456 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9489517 — Surrogate Endpoint (SUR): Blood pressure
Study 30279194 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30279194 — Monitoring Biomarker (MOI): Cell-free DNA
Study 18855992 — Predictive Biomarker (PRD): SOBP mRNA
Genes: SOBP; JXC1
Study 3067179 — Surrogate Endpoint (SUR): Blood pressure
Study 20865582 — Surrogate Endpoint (SUR): Blood pressure
Study 20139785 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 20139785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31796304 — Surrogate Endpoint (SUR): Blood pressure
Study 1959410 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25222305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29806081 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 12923146 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 28986164 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 24127651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24127651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24993981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20887614 — Surrogate Endpoint (SUR): Blood pressure
Study 11789238 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8815119 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1504127 — Surrogate Endpoint (SUR): Blood pressure
Study 6091245 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 18971897 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 18602742 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12819322 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3217807 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29875101 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 26150601 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 9764968 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9764968 — Surrogate Endpoint (SUR): Blood pressure
Study 2238184 — Surrogate Endpoint (SUR): Blood pressure
Study 30691153 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 16724576 — Surrogate Endpoint (SUR): Blood pressure
Study 14606098 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 14606098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 14606098 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14606098 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10206118 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10206118 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7540413 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7150174 — Surrogate Endpoint (SUR): Blood pressure
Study 28163000 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23439606 — Surrogate Endpoint (SUR): Serum uric acid
Study 23439606 — Surrogate Endpoint (SUR): Blood pressure
Study 15020607 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9762483 — Surrogate Endpoint (SUR): Blood pressure
Study 12872393 — Predictive Biomarker (PRD): DHDDS mRNA
Genes: DHDDS; HDS
Study 10561764 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8885761 — Surrogate Endpoint (SUR): Blood pressure
Study 23176112 — Safety Biomarker (SAF): Hyaluronic acid
Study 12091332 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10599711 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31335881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31335881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23167925 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 22082582 — Surrogate Endpoint (SUR): Blood pressure
Study 10645920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8436156 — Surrogate Endpoint (SUR): Blood pressure
Study 3256414 — Surrogate Endpoint (SUR): Blood pressure
Study 20497513 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 20497513 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 18617483 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16416313 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 16416313 — Surrogate Endpoint (SUR): Blood pressure
Study 16416313 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 16416313 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23435143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18294318 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 15808240 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15808240 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 12554899 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8814494 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 1323324 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31841498 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 31841498 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 6760680 — Surrogate Endpoint (SUR): Blood pressure
Study 31149870 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22378036 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1737667 — Surrogate Endpoint (SUR): Blood pressure
Study 6483118 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 6483118 — Surrogate Endpoint (SUR): Blood pressure
Study 18420096 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 10815894 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10815894 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10815894 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF