TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10606227 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A2 mRNA
Genes: SRD5A2
Study 8959943 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2977404 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2977404 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2977404 — Surrogate Endpoint (SUR): Blood pressure
Study 31020392 — Predictive Biomarker (PRD); Safety Biomarker (SAF): STAR mRNA
Genes: STAR; STARD1
Study 30113228 — Predictive Biomarker (PRD): NBL1 mRNA
Genes: NBL1; DAN; DAND1
Study 30113228 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 19022322 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9591000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23582626 — Surrogate Endpoint (SUR): Blood pressure
Study 17062213 — Surrogate Endpoint (SUR): Blood pressure
Study 10969352 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24782083 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24782083 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20150294 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 11912262 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11912262 — Surrogate Endpoint (SUR): Blood pressure
Study 20865421 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20218030 — Surrogate Endpoint (SUR): Blood pressure
Study 7509619 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 25850708 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22079655 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 19920107 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19920107 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 15187818 — Surrogate Endpoint (SUR): Blood pressure
Study 15187818 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2427841 — Surrogate Endpoint (SUR): Blood pressure
Study 17028508 — Surrogate Endpoint (SUR): Blood pressure
Study 12756930 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 1973591 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17653960 — Surrogate Endpoint (SUR): Blood pressure
Study 8084808 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 806790 — Surrogate Endpoint (SUR): Blood pressure
Study 11230783 — Surrogate Endpoint (SUR): Blood pressure
Study 31954186 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31954186 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31954186 — Safety Biomarker (SAF): BDNF
Study 31954186 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28707086 — Safety Biomarker (SAF): Hyaluronic acid
Study 24936126 — Monitoring Biomarker (MOI): HBV DNA
Study 7603605 — Surrogate Endpoint (SUR): Bone mineral density
Study 19828234 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 15639697 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22230825 — Surrogate Endpoint (SUR): Blood pressure
Study 22230825 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18263673 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11053824 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8805887 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 1640003 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 6234015 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 24561732 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 19237681 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15126526 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3388180 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27085251 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study 27085251 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 18568181 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7180061 — Surrogate Endpoint (SUR): Blood pressure
Study 12714876 — Surrogate Endpoint (SUR): Blood pressure
Study 24836352 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 24836352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24836352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10230249 — Surrogate Endpoint (SUR): Blood pressure
Study 8691860 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28927961 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 10374220 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27901117 — Surrogate Endpoint (SUR): Serum uric acid
Study 22964150 — Monitoring Biomarker (MOI): HBV DNA
Study 11222785 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31711153 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29382478 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 25157676 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 22766391 — Predictive Biomarker (PRD): CHRNA7 mRNA
Genes: CHRNA7; NACHRA7
Study 21472661 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9335405 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9335405 — Surrogate Endpoint (SUR): Blood pressure
Study 15585690 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 15585690 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 15585690 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 15585690 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11961504 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30525347 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30525347 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24374246 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 20637539 — Predictive Biomarker (PRD): PCA3
Study 17761004 — Predictive Biomarker (PRD): CRCP mRNA
Genes: CRCP
Study 31090673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31090673 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 24824408 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 24824408 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17998507 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1766047 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 25882604 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 25882604 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25882604 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study 25882604 — Safety Biomarker (SAF): MTHFR
Study 24149738 — Surrogate Endpoint (SUR): Blood pressure
Study 11331213 — Predictive Biomarker (PRD): TSHR mRNA
Genes: TSHR; LGR3
Study 7970996 — Surrogate Endpoint (SUR): Serum uric acid
Study 238810 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 28478093 — Predictive Biomarker (PRD): TKFC mRNA
Genes: TKFC; DAK
Study 28478093 — Surrogate Endpoint (SUR): Blood pressure
Study 15686716 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15686716 — Surrogate Endpoint (SUR): Blood pressure
Study 31157962 — Predictive Biomarker (PRD): Hormone receptor
Study 25078879 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 7983235 — Surrogate Endpoint (SUR): Blood pressure
Study 2512486 — Surrogate Endpoint (SUR): Serum creatinine
Study 2512486 — Surrogate Endpoint (SUR): Blood pressure
Study 16618834 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16618834 — Surrogate Endpoint (SUR): Blood pressure
Study 12510011 — Surrogate Endpoint (SUR): Serum testosterone
Study 9200991 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23906400 — Surrogate Endpoint (SUR): Blood pressure
Study 19595142 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study 16563905 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9675383 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26766905 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 15862370 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 31179339 — Safety Biomarker (SAF): Reactive oxygen species
Study 31179339 — Surrogate Endpoint (SUR): Serum creatinine
Study 25216597 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25216597 — Surrogate Endpoint (SUR): Blood pressure
Study 25216597 — Surrogate Endpoint (SUR): Serum uric acid
Study 22180403 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 11101062 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11101062 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31324597 — Predictive Biomarker (PRD): SACS mRNA
Genes: SACS; KIAA0730
Study 30345905 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 30345905 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30345905 — Predictive Biomarker (PRD): Hormone receptor
Study 19189783 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 11740974 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11740974 — Safety Biomarker (SAF): IL-6 and IL-10
Study 20620713 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29111391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15917384 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12526955 — Surrogate Endpoint (SUR): Blood pressure
Study 10563070 — Surrogate Endpoint (SUR): Blood pressure
Study 8730416 — Surrogate Endpoint (SUR): Blood pressure
Study 17913961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10726107 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7862217 — Surrogate Endpoint (SUR): Blood pressure
Study 220889 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11168516 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 30488350 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 26258451 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24124451 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9149330 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 2906343 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20406217 — Surrogate Endpoint (SUR): Blood pressure
Study 18925531 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18925531 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 7596116 — Surrogate Endpoint (SUR): Serum sodium
Study 7596116 — Surrogate Endpoint (SUR): Blood pressure
Study 23140261 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23140261 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9498287 — Safety Biomarker (SAF): Reactive oxygen species
Study 26378681 — Surrogate Endpoint (SUR): Blood pressure
Study 23826645 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 16151030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16151030 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7783313 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 2128828 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 31250758 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 31250758 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 31250758 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 31250758 — Predictive Biomarker (PRD): TIMP2 mRNA
Genes: TIMP2
Study 18844508 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study 9373050 — Surrogate Endpoint (SUR): Serum creatinine
Study 9373050 — Surrogate Endpoint (SUR): Blood pressure
Study 18433425 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 18433425 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12045679 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9528731 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9528731 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9528731 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2104939 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2104939 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29386335 — Surrogate Endpoint (SUR): Blood pressure
Study 20594395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20594395 — Surrogate Endpoint (SUR): Blood pressure
Study 12418945 — Surrogate Endpoint (SUR): Blood pressure
Study 12418945 — Surrogate Endpoint (SUR): Serum creatinine
Study 7737719 — Surrogate Endpoint (SUR): Blood pressure
Study 7021994 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 23603204 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21093145 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19275490 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19275490 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19275490 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19275490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1921253 — Surrogate Endpoint (SUR): Blood pressure
Study 6354604 — Surrogate Endpoint (SUR): Blood pressure
Study 18822974 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 18822974 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 10606107 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 17959958 — Surrogate Endpoint (SUR): Blood pressure
Study 31126331 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 17909201 — Monitoring Biomarker (MOI): HBV DNA
Study 27290958 — Surrogate Endpoint (SUR): Blood pressure
Study 22538219 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30576866 — Surrogate Endpoint (SUR): Bone mineral density
Study 15167310 — Surrogate Endpoint (SUR): Bone mineral density
Study 282081 — Surrogate Endpoint (SUR): Blood pressure
Study 21917481 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 31848294 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 31848294 — Surrogate Endpoint (SUR): Serum potassium
Study 18194116 — Surrogate Endpoint (SUR): Serum creatinine
Study 18194116 — Surrogate Endpoint (SUR): Blood pressure
Study 31985301 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 26990279 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 23937421 — Surrogate Endpoint (SUR): Bone mineral density
Study 23937421 — Surrogate Endpoint (SUR): Serum creatinine
Study 17430984 — Predictive Biomarker (PRD): LIFR mRNA
Genes: LIFR
Study 1352246 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30037035 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23625867 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 15867235 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15867235 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15867235 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30893060 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 30893060 — Predictive Biomarker (PRD): SIRT2 mRNA
Genes: SIRT2; SIR2L; SIR2L2
Study 30893060 — Predictive Biomarker (PRD): AXIN1 mRNA
Genes: AXIN1; AXIN
Study 28931981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23288035 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 8614385 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1451343 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 7617817 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1975483 — Surrogate Endpoint (SUR): Blood pressure
Study 15907417 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 15907417 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9806660 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10649920 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31358017 — Predictive Biomarker (PRD): ZFYVE9 mRNA
Genes: ZFYVE9; MADHIP; SARA; SMADIP
Study 28686822 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 21448303 — Surrogate Endpoint (SUR): Bone mineral density
Study 18502257 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15673893 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 9024515 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 7862826 — Surrogate Endpoint (SUR): Blood pressure
Study 2890591 — Surrogate Endpoint (SUR): Blood pressure
Study 15860688 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 31694220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31694220 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14683738 — Surrogate Endpoint (SUR): Blood pressure
Study 9468065 — Surrogate Endpoint (SUR): Blood pressure
Study 7893035 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 2575480 — Surrogate Endpoint (SUR): Blood pressure
Study 28535400 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21243736 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10764900 — Surrogate Endpoint (SUR): Blood pressure
Study 23044768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21039208 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19576339 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 2900132 — Surrogate Endpoint (SUR): Blood pressure
Study 31019123 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 15229392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18191645 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31532137 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 26467531 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26467531 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 26467531 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 26467531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26467531 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 26467531 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 7964860 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 31301533 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 19842940 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 19842940 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 10972632 — Surrogate Endpoint (SUR): Blood pressure
Study 10972632 — Surrogate Endpoint (SUR): Serum creatinine
Study 12580211 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 1612530 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 24388920 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8501579 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31958337 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 27922950 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 23187726 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 21996393 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 14676787 — Surrogate Endpoint (SUR): Hematologic response
Study 3752487 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 31658396 — Safety Biomarker (SAF): Interleukin 1
Study 27891663 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 27891663 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25686055 — Safety Biomarker (SAF): Reactive oxygen species
Study 21527519 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 1642185 — Surrogate Endpoint (SUR): Blood pressure
Study 6463180 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 22343483 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 8637449 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 8637449 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 8637449 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 2206032 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22170972 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 10465068 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7494809 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31731005 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 31093755 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 31093755 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 18785846 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 16626571 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11239180 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR