TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22031518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19189517 — Surrogate Endpoint (SUR): Blood pressure
Study 8661977 — Surrogate Endpoint (SUR): Bone mineral density
Study 20438307 — Surrogate Endpoint (SUR): Blood pressure
Study 11910262 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10327575 — Safety Biomarker (SAF): IL-6 and IL-10
Study 30376747 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 26664304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19903982 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19903982 — Surrogate Endpoint (SUR): Blood pressure
Study 12916666 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27709360 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14607573 — Safety Biomarker (SAF): MTHFR
Study 8018144 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10070170 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10070170 — Surrogate Endpoint (SUR): Blood pressure
Study 31517505 — Surrogate Endpoint (SUR): Blood pressure
Study 25622599 — Predictive Biomarker (PRD): ACY3 mRNA
Genes: ACY3; ASPA2
Study 25622599 — Predictive Biomarker (PRD): NPHS1 mRNA
Genes: NPHS1; NPHN
Study 25622599 — Predictive Biomarker (PRD): ALDH1A3 mRNA
Genes: ALDH1A3; ALDH6
Study 25622599 — Predictive Biomarker (PRD): CLIC5 mRNA
Genes: CLIC5
Study 9286238 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31563820 — Predictive Biomarker (PRD): VARS1 mRNA
Genes: VARS1; G7A; VARS; VARS2
Study 15974489 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 12324914 — Safety Biomarker (SAF): Reactive oxygen species
Study 7862660 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6115104 — Surrogate Endpoint (SUR): Serum creatinine
Study 28415975 — Surrogate Endpoint (SUR): Blood pressure
Study 23117205 — Predictive Biomarker (PRD): VASH1 mRNA
Genes: VASH1; KIAA1036; VASH
Study 15802775 — Surrogate Endpoint (SUR): Bone mineral density
Study 29108091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24417761 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 24417761 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 24417761 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22650767 — Surrogate Endpoint (SUR): Blood pressure
Study 12525719 — Surrogate Endpoint (SUR): Blood pressure
Study 8730607 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25979975 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 23417317 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 11548448 — Surrogate Endpoint (SUR): Blood pressure
Study 7921924 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21531233 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11581068 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7888231 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7888231 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 3345623 — Surrogate Endpoint (SUR): Blood pressure
Study 23901664 — Surrogate Endpoint (SUR): Blood pressure
Study 23901664 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14660990 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2663164 — Surrogate Endpoint (SUR): Blood pressure
Study 18496196 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 18496196 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 9167099 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27557561 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 27557561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 10418841 — Surrogate Endpoint (SUR): Blood pressure
Study 2048514 — Surrogate Endpoint (SUR): Blood pressure
Study 24128075 — Surrogate Endpoint (SUR): Blood pressure
Study 18092260 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21916908 — Surrogate Endpoint (SUR): Bone mineral density
Study 19673711 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 9407512 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8100152 — Surrogate Endpoint (SUR): Blood pressure
Study 22976604 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 19470037 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10448289 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 373100 — Surrogate Endpoint (SUR): Blood pressure
Study 373100 — Surrogate Endpoint (SUR): Serum sodium
Study 373100 — Surrogate Endpoint (SUR): Serum potassium
Study 373100 — Surrogate Endpoint (SUR): Serum calcium
Study 373100 — Surrogate Endpoint (SUR): Serum creatinine
Study 373100 — Surrogate Endpoint (SUR): Serum uric acid
Study 17543781 — Surrogate Endpoint (SUR): Serum creatinine
Study 15480108 — Surrogate Endpoint (SUR): Blood pressure
Study 26240957 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 23396206 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17679043 — Surrogate Endpoint (SUR): Blood pressure
Study 17679043 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15060258 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15060258 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 17447116 — Surrogate Endpoint (SUR): Bone mineral density
Study 26423649 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19142802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11257560 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 23719547 — Surrogate Endpoint (SUR): Bone mineral density
Study 19449238 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8458113 — Surrogate Endpoint (SUR): Blood pressure
Study 28238045 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 18554243 — Monitoring Biomarker (MOI): HBV DNA
Study 1392698 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 19648781 — Predictive Biomarker (PRD): CRABP2 mRNA
Genes: CRABP2
Study 19648781 — Predictive Biomarker (PRD): HBEGF mRNA
Genes: HBEGF; DTR; DTS; HEGFL
Study 11916359 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11916359 — Surrogate Endpoint (SUR): Blood pressure
Study 2904881 — Surrogate Endpoint (SUR): Blood pressure
Study 9692538 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 25563714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20199815 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 27817096 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 11915588 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 1830287 — Surrogate Endpoint (SUR): Blood pressure
Study 22093775 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 22093775 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10404423 — Predictive Biomarker (PRD): DMTN mRNA
Genes: DMTN; DMT; EPB49
Study 10404423 — Predictive Biomarker (PRD): TCHH mRNA
Genes: TCHH; THH; THL; TRHY
Study 26372211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26372211 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28087807 — Predictive Biomarker (PRD): LAMB2 mRNA
Genes: LAMB2; LAMS
Study 19765449 — Surrogate Endpoint (SUR): Blood pressure
Study 19765449 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19765449 — Surrogate Endpoint (SUR): Serum creatinine
Study 19765449 — Surrogate Endpoint (SUR): Serum potassium
Study 19765449 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14984856 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 28821686 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 28821686 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 28821686 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17106267 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29429057 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 29429057 — Predictive Biomarker (PRD): ZDHHC2 mRNA
Genes: ZDHHC2; REAM; REC; ZNF372
Study 24448757 — Surrogate Endpoint (SUR): Serum creatinine
Study 24448757 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21900941 — Surrogate Endpoint (SUR): Blood pressure
Study 18954260 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 18954260 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 12488271 — Surrogate Endpoint (SUR): Blood pressure
Study 20088738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20088738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10225478 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10225478 — Surrogate Endpoint (SUR): Blood pressure
Study 95728 — Surrogate Endpoint (SUR): Blood pressure
Study 21256308 — Surrogate Endpoint (SUR): Serum creatinine
Study 7828793 — Surrogate Endpoint (SUR): Blood pressure
Study 30113526 — Surrogate Endpoint (SUR): Blood pressure
Study 30113526 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25516338 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22951014 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22951014 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18256841 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18256841 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7491837 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7491837 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 7491837 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28031424 — Predictive Biomarker (PRD): ALK
Genes: CD246; ALK1
Study 28031424 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 8960715 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26702991 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 12634965 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1888238 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31892609 — Surrogate Endpoint (SUR): Serum calcium
Study 25376940 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 12860772 — Safety Biomarker (SAF): DRD2
Study 24374073 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 24374073 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23529990 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 12212923 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25481791 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 25481791 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 19004023 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 9589245 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9589245 — Surrogate Endpoint (SUR): Blood pressure
Study 2644175 — Surrogate Endpoint (SUR): Serum potassium
Study 30826452 — Surrogate Endpoint (SUR): Blood pressure
Study 17052581 — Surrogate Endpoint (SUR): Blood pressure
Study 10381854 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10381854 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10381854 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7037664 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28412650 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 28412650 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 25416687 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 24554598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24554598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24554598 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7576677 — Surrogate Endpoint (SUR): Blood pressure
Study 18667054 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 15177704 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 23211514 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 10668942 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 6344715 — Surrogate Endpoint (SUR): Serum creatinine
Study 30794084 — Surrogate Endpoint (SUR): Serum testosterone
Study 22581994 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 10798126 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 29910795 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 29910795 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24625530 — Surrogate Endpoint (SUR): Bone mineral density
Study 3882583 — Surrogate Endpoint (SUR): Blood pressure
Study 30336580 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 30336580 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30336580 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18843564 — Surrogate Endpoint (SUR): Blood pressure
Study 8881809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30156758 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30351407 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18812486 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18812486 — Surrogate Endpoint (SUR): Bone mineral density
Study 29161531 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25627338 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12754273 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12754273 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 12754273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12754273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12754273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12754273 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 11063956 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9042265 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 9042265 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 7538658 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30969323 — Surrogate Endpoint (SUR): Blood pressure
Study 23432777 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19200542 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8562296 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30842065 — Predictive Biomarker (PRD): JMJD1C mRNA
Genes: JMJD1C; JHDM2C; KIAA1380; TRIP8
Study 30842065 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24083696 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10958384 — Safety Biomarker (SAF): Reactive oxygen species
Study 10958384 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12011664 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12011664 — Surrogate Endpoint (SUR): Blood pressure
Study 12011664 — Surrogate Endpoint (SUR): Serum creatinine
Study 6407638 — Surrogate Endpoint (SUR): Blood pressure
Study 30410653 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study 23645068 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 6896672 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 30235385 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 30235385 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 26598747 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 24339179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19189371 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 9688295 — Predictive Biomarker (PRD): TIMM8A mRNA
Genes: TIMM8A; DDP; DDP1; TIM8A
Study 15882713 — Surrogate Endpoint (SUR): Serum creatinine
Study 3882364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26633188 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 26633188 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26633188 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 25035603 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12764986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3020960 — Surrogate Endpoint (SUR): Serum calcium
Study 29573247 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 18641716 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 18641716 — Predictive Biomarker (PRD): ABCG8 mRNA
Genes: ABCG8
Study 18641716 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study 18641716 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30878487 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26639151 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22641493 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17501954 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 25446217 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 11347287 — Surrogate Endpoint (SUR): Blood pressure
Study 3693583 — Surrogate Endpoint (SUR): Blood pressure
Study 20718826 — Surrogate Endpoint (SUR): Serum creatinine
Study 17339866 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1103724 — Surrogate Endpoint (SUR): Serum creatinine
Study 17302248 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10729390 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 10729390 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 9013080 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25236915 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9389897 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 9389897 — Surrogate Endpoint (SUR): Blood pressure
Study 3370401 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29467025 — Surrogate Endpoint (SUR): Blood pressure
Study 25690266 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 25690266 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 12679174 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 12679174 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29532078 — Surrogate Endpoint (SUR): Blood pressure
Study 27002003 — Surrogate Endpoint (SUR): Blood pressure
Study 20357370 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 15793608 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1823632 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 6367857 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11232529 — Surrogate Endpoint (SUR): Blood pressure
Study 1572085 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10952732 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 10952732 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 10354193 — Surrogate Endpoint (SUR): Blood pressure
Study 23684734 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19631705 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 10746493 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8930946 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 12699480 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12699480 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8938538 — Predictive Biomarker (PRD): Liver iron
Study 23377167 — Surrogate Endpoint (SUR): Blood pressure
Study 23739436 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 20620200 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 11154093 — Predictive Biomarker (PRD): PRX mRNA
Genes: PRX; KIAA1620
Study 11154093 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 27461877 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 12571616 — Surrogate Endpoint (SUR): Blood pressure
Study 6794796 — Surrogate Endpoint (SUR): Blood pressure
Study 28181738 — Surrogate Endpoint (SUR): Blood pressure
Study 28181738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23803704 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23803704 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402