TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20061337 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 20061337 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2193271 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2193271 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26914909 — Surrogate Endpoint (SUR): Serum creatinine
Study 24636483 — Surrogate Endpoint (SUR): Blood pressure
Study 26121561 — Surrogate Endpoint (SUR): Blood pressure
Study 23874572 — Predictive Biomarker (PRD): RAB8A mRNA
Genes: RAB8A; MEL; RAB8
Study 3169222 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31162898 — Surrogate Endpoint (SUR): Serum creatinine
Study 31162898 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 9126668 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9126668 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30757908 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30757908 — Surrogate Endpoint (SUR): Blood pressure
Study 17097752 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7661413 — Surrogate Endpoint (SUR): Blood pressure
Study 29316905 — Surrogate Endpoint (SUR): Blood pressure
Study 31654312 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31002283 — Surrogate Endpoint (SUR): Blood pressure
Study 21778330 — Predictive Biomarker (PRD): ETV4 mRNA
Genes: ETV4; E1AF; PEA3
Study 21778330 — Predictive Biomarker (PRD): ETV5 mRNA
Genes: ETV5; ERM
Study 21778330 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21778330 — Predictive Biomarker (PRD): DNAJC12 mRNA
Genes: DNAJC12; JDP1
Study 11748517 — Surrogate Endpoint (SUR): Blood pressure
Study 8302441 — Surrogate Endpoint (SUR): Blood pressure
Study 22005174 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 15901634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2500138 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 21813073 — Predictive Biomarker (PRD): XKR4 mRNA
Genes: XKR4; KIAA1889; XRG4
Study 21813073 — Predictive Biomarker (PRD): GRIA4 mRNA
Genes: GRIA4; GLUR4
Study 19034126 — Safety Biomarker (SAF): Hyaluronic acid
Study 16025230 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14728070 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 31132967 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 23955138 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23955138 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 17127704 — Monitoring Biomarker (MOI): HBV DNA
Study 3060429 — Surrogate Endpoint (SUR): Blood pressure
Study 3060429 — Surrogate Endpoint (SUR): Serum triglycerides
Study 3060429 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3060429 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20644014 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 18928483 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16352396 — Predictive Biomarker (PRD): GLO1 mRNA
Genes: GLO1
Study 11876692 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 6623019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1933049 — Surrogate Endpoint (SUR): Blood pressure
Study 6786895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 21900595 — Predictive Biomarker (PRD): Microsatellite instability
Study 19143021 — Predictive Biomarker (PRD): HSPA1B mRNA
Genes: HSPA1B; HSP72
Study 19143021 — Predictive Biomarker (PRD): SERPINH1 mRNA
Genes: SERPINH1; CBP1; CBP2; HSP47; SERPINH2; PIG14
Study 19143021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19143021 — Safety Biomarker (SAF): Hyaluronic acid
Study 19143021 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 28077734 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22180357 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22180357 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2856549 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22030224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22030224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14687438 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14687438 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 4025299 — Surrogate Endpoint (SUR): Blood pressure
Study 26777722 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26777722 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26777722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26777722 — Surrogate Endpoint (SUR): Blood pressure
Study 8694320 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31298705 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ADAM11 mRNA
Genes: ADAM11; MDC
Study 30641621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30641621 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30641621 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30641621 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 22019331 — Surrogate Endpoint (SUR): Serum calcium
Study 22019331 — Surrogate Endpoint (SUR): Serum creatinine
Study 22019331 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 22019331 — Surrogate Endpoint (SUR): Blood pressure
Study 15194570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3203571 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19767761 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11019420 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study 25069991 — Surrogate Endpoint (SUR): Blood pressure
Study 25069991 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25069991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25069991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16563281 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 16563281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31883845 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 31883845 — Predictive Biomarker (PRD): KRT16 mRNA
Genes: KRT16; KRT16A
Study 16600934 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 8773944 — Surrogate Endpoint (SUR): Blood pressure
Study 1729854 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30537550 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 30537550 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 30537550 — Surrogate Endpoint (SUR): Hematologic response
Study 22150098 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11864795 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11864795 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11864795 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15451907 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25801162 — Surrogate Endpoint (SUR): Blood pressure
Study 23686563 — Safety Biomarker (SAF): Reactive oxygen species
Study 9706914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24677033 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 22952648 — Predictive Biomarker (PRD): TFAP2B mRNA
Genes: TFAP2B
Study 15339465 — Predictive Biomarker (PRD): NOS3 mRNA
Genes: NOS3
Study 23667063 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 16176939 — Surrogate Endpoint (SUR): Bone mineral density
Study 9170576 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 20068365 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11281338 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9400948 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9576366 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9576366 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 26882121 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 26882121 — Predictive Biomarker (PRD): NR1I2 mRNA
Genes: NR1I2; PXR
Study 26882121 — Predictive Biomarker (PRD): NR1I2
Genes: ONR1; PXR; BXR; SXR; PAR2
Study 19480232 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 15143081 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31862436 — Surrogate Endpoint (SUR): Blood pressure
Study 10828762 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 10828762 — Predictive Biomarker (PRD): PRKD1 mRNA
Genes: PRKD1; PKD; PKD1; PRKCM
Study 21219197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21219197 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12562650 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12562650 — Predictive Biomarker (PRD): Hormone receptor
Study 9140792 — Surrogate Endpoint (SUR): Blood pressure
Study 29667902 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26815880 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 26815880 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 11591950 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11591950 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 11591950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11591950 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11591950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2686711 — Surrogate Endpoint (SUR): Blood pressure
Study 30881904 — Surrogate Endpoint (SUR): Blood pressure
Study 23460569 — Surrogate Endpoint (SUR): Blood pressure
Study 24655694 — Surrogate Endpoint (SUR): Blood pressure
Study 22453003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20038734 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19094763 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8927288 — Surrogate Endpoint (SUR): Bone mineral density
Study 6507769 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 17926466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9794352 — Surrogate Endpoint (SUR): Blood pressure
Study 2128265 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 2128265 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2128265 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 110184 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 31492784 — Surrogate Endpoint (SUR): Bone mineral density
Study 31492784 — Surrogate Endpoint (SUR): Blood pressure
Study 25827058 — Surrogate Endpoint (SUR): Blood pressure
Study 24246211 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24246211 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 21575919 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21575919 — Surrogate Endpoint (SUR): Blood pressure
Study 8193987 — Surrogate Endpoint (SUR): Blood pressure
Study 2464094 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26365445 — Surrogate Endpoint (SUR): Blood pressure
Study 24262440 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24262440 — Predictive Biomarker (PRD): GRB7 mRNA
Genes: GRB7
Study 24262440 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24262440 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study 24262440 — Predictive Biomarker (PRD): CA12 mRNA
Genes: CA12
Study 24262440 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 8190296 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 31951276 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23314743 — Surrogate Endpoint (SUR): Blood pressure
Study 22108151 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22108151 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22108151 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17197848 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15166915 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 20677606 — Surrogate Endpoint (SUR): Blood pressure
Study 15777971 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 1601764 — Surrogate Endpoint (SUR): Serum creatinine
Study 30843873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30843873 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 19013718 — Predictive Biomarker (PRD): 14-3-3 protein sigma
Genes: SFN; HME1
Study 3075406 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3075406 — Surrogate Endpoint (SUR): Blood pressure
Study 20689757 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 20689757 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 18464745 — Surrogate Endpoint (SUR): Blood pressure
Study 12946228 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8666137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29360778 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 16632108 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 10561270 — Predictive Biomarker (PRD): TOX mRNA
Genes: TOX; KIAA0808
Study 10561270 — Predictive Biomarker (PRD): TWIST1 mRNA
Genes: TWIST1; BHLHA38; TWIST
Study 29105802 — Safety Biomarker (SAF): miR-200a
Genes: MIR200A
Study 29105802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-210
Genes: MIR210
Study 29105802 — Safety Biomarker (SAF): miR-375
Genes: MIR375
Study 28870163 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20622200 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20622200 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16595163 — Predictive Biomarker (PRD): PDLIM5 mRNA
Genes: PDLIM5; ENH; L9
Study 8320445 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 3743615 — Surrogate Endpoint (SUR): Blood pressure
Study 28651844 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 19052124 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8981490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8772602 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8772602 — Predictive Biomarker (PRD): PTGDS mRNA
Genes: PTGDS; PDS
Study 26691646 — Surrogate Endpoint (SUR): Blood pressure
Study 21531124 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21531124 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22776970 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22776970 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22776970 — Surrogate Endpoint (SUR): Blood pressure
Study 27966574 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21423115 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 29190319 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25687834 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 10822898 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20056625 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 12115017 — Surrogate Endpoint (SUR): Blood pressure
Study 27572070 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25015544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25015544 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16351669 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31860160 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 18937325 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18937325 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 18937325 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11510750 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11510750 — Surrogate Endpoint (SUR): Blood pressure
Study 11510750 — Surrogate Endpoint (SUR): Serum creatinine
Study 31831886 — Surrogate Endpoint (SUR): Blood pressure
Study 25687353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20642207 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18622266 — Predictive Biomarker (PRD): CRHR1 mRNA
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 16306470 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 12682474 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29446041 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 25714132 — Surrogate Endpoint (SUR): Blood pressure
Study 27253458 — Surrogate Endpoint (SUR): Blood pressure
Study 15928258 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15928258 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31067545 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 20922542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20922542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20922542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20922542 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 20922542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31754238 — Surrogate Endpoint (SUR): Blood pressure
Study 31754238 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31718297 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31718297 — Surrogate Endpoint (SUR): Blood pressure
Study 9298381 — Surrogate Endpoint (SUR): Blood pressure
Study 30025392 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20042477 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 17947726 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 10812235 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20459883 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17609404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17609404 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17609404 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15576654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2115298 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26462480 — Surrogate Endpoint (SUR): Bone mineral density
Study 24856782 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 22114792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22114792 — Safety Biomarker (SAF): Reactive oxygen species
Study 15542043 — Surrogate Endpoint (SUR): Bone mineral density
Study 7946177 — Surrogate Endpoint (SUR): Blood pressure
Study 25696967 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 25696967 — Predictive Biomarker (PRD): SERPINB6 mRNA
Genes: SERPINB6; PI6; PTI
Study 27324882 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19367427 — Surrogate Endpoint (SUR): Blood pressure
Study 9563139 — Surrogate Endpoint (SUR): Serum testosterone
Study 31910819 — Surrogate Endpoint (SUR): Blood pressure
Study 27686283 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23638799 — Surrogate Endpoint (SUR): Blood pressure
Study 20607595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20607595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20607595 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 11360159 — Surrogate Endpoint (SUR): Blood pressure
Study 31832749 — Predictive Biomarker (PRD): BLVRA mRNA
Genes: BLVRA; BLVR; BVR
Study 24023320 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 18192839 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1