TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02776891 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT03080428 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00899171 — Predictive Biomarker (PRD): IRF8 mRNA
Genes: IRF8; ICSBP1
Study NCT04163419 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04325412 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00001959 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01096017 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00064285 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT03845452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03845452 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03929458 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT03929458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03929458 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05764941 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01813253 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02391779 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01958944 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01958944 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study NCT04494061 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study NCT04494061 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02027012 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00833482 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00278122 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04581954 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT02875808 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT02919228 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02322801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03224351 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT03224351 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study NCT01542437 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01542437 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01542437 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT01835938 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01835938 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03605173 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT00131027 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02441127 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT04508946 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00902590 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study NCT00902590 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study NCT02643121 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT02643121 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT01560806 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02043002 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02043002 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00797381 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05005923 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study NCT05005923 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT05005923 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT05005923 — Predictive Biomarker (PRD): IL34 mRNA
Genes: IL34; C16orf77
Study NCT04326920 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02313220 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00110110 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study NCT02693808 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00993343 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT04747717 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03465670 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00786669 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04540263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03546036 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03115138 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02179970 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT02112331 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT04731740 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT04731740 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT04731740 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT03362190 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT01573988 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT01573988 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT01344265 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00842569 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT00917683 — Predictive Biomarker (PRD): SERPINI1 mRNA
Genes: SERPINI1; PI12
Study NCT02961608 — Predictive Biomarker (PRD): FKBP1A mRNA
Genes: FKBP1A; FKBP1; FKBP12
Study NCT03358563 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT00425035 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03169127 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT04635995 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04635995 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT02726711 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03264859 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04604535 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04417673 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00028496 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00028496 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00976989 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00976989 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03244085 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00006155 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00006155 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT04473131 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01360931 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01360931 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01360931 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01360931 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study NCT03089333 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03089333 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03679039 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02655029 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03741153 — Predictive Biomarker (PRD): PHEX mRNA
Genes: PHEX; PEX
Study NCT00434005 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT01447654 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00821574 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02857517 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02857517 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01406951 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01406951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05672810 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00970801 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT04544748 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT01258608 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT03246152 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03246152 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01147042 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01719835 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT03135730 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study NCT00819598 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03361969 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT01639781 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00509184 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT04362072 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03991312 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00287495 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04001166 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT04001166 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT00584610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00584610 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT02129257 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02129257 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT04275323 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT03401307 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT03401307 — Predictive Biomarker (PRD): MPZ mRNA
Genes: MPZ
Study NCT03401307 — Pharmacodynamic Biomarker (PDY): Peripheral myelin protein 22
Genes: PMP22; GAS3
Study NCT03401307 — Safety Biomarker (SAF): BDNF
Study NCT03401307 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04354467 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT04354467 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01840007 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT00520325 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT02064491 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00682890 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00683670 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03654716 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT03654716 — Predictive Biomarker (PRD): MDM4 mRNA
Genes: MDM4; MDMX
Study NCT04303741 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01235390 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT02529722 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03575663 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01802736 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05039814 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT00016237 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01601639 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT01706458 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT02760940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02760940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03099499 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study NCT03099499 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study NCT03099499 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03099499 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study NCT04088227 — Safety Biomarker (SAF): Interleukin 1
Study NCT01472016 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02648282 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00963417 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03089268 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01430871 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02163759 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02910895 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT01312012 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00601094 — Predictive Biomarker (PRD): CCL21 mRNA
Genes: CCL21; SCYA21; UNQ784/PRO1600
Study NCT01748877 — Predictive Biomarker (PRD): NXN mRNA
Genes: NXN; NRX
Study NCT00201084 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03918655 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT03918655 — Predictive Biomarker (PRD): CD74 mRNA
Genes: CD74; DHLAG
Study NCT03918655 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT03918655 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study NCT03918655 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study NCT03918655 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03575988 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT00757341 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study NCT04222101 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT02481154 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT02481154 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT03971682 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT00329511 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02561065 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00624949 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01129466 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT01150526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01150526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01579591 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02140047 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study NCT00572377 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03977090 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT04322838 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT04322838 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03186131 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04557943 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT01047293 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01047293 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03253289 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT00757783 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03300115 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02443948 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT03882060 — Predictive Biomarker (PRD): RNF213 mRNA
Genes: RNF213; ALO17; C17orf27; KIAA1554; KIAA1618; MYSTR
Study NCT00936234 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03960541 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02788890 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02990312 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT04348760 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study NCT03808090 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT03252808 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT01213394 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00003605 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00302809 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01806220 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01806220 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01830725 — Predictive Biomarker (PRD): XDH mRNA
Genes: XDH; XDHA
Study NCT01830725 — Safety Biomarker (SAF): Hypoxanthine-guanine phosphoribosyltransferase
Genes: HPRT1; HPRT
Study NCT01830725 — Predictive Biomarker (PRD): PRPS1 mRNA
Genes: PRPS1
Study NCT01830725 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT01033240 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT00074165 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT00802295 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT05288660 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study NCT02364323 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02364323 — Predictive Biomarker (PRD): PRKCB mRNA
Genes: PRKCB; PKCB; PRKCB1
Study NCT02364323 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02007798 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02598791 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02113904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03188848 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT01436188 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02723942 — Predictive Biomarker (PRD): GPC3 mRNA
Genes: GPC3; OCI5
Study NCT02105623 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03935126 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02869100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02869100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02655848 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study NCT01257425 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT03106909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03106909 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT00552487 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT03298802 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04633551 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00918385 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02430545 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01741727 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01741727 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01795833 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01795833 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT02691819 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT02691819 — Predictive Biomarker (PRD): TNNT1 mRNA
Genes: TNNT1; TNT
Study NCT02395757 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02395757 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00071006 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00071006 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02264925 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study NCT02667977 — Surrogate Endpoint (SUR): Serum sodium
Study NCT03081637 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FLNA mRNA
Genes: FLNA; FLN; FLN1
Study NCT02774460 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02774460 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00561652 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT00905112 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT01744379 — Surrogate Endpoint (SUR): Serum uric acid