TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30389229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27748235 — Surrogate Endpoint (SUR): Blood pressure
Study 23823132 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 7912085 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3354029 — Surrogate Endpoint (SUR): Blood pressure
Study 12545845 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19674252 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 17652885 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17652885 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7772628 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23061430 — Surrogate Endpoint (SUR): Blood pressure
Study 19526756 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19526756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19526756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19526756 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16924025 — Predictive Biomarker (PRD): GABRG2 mRNA
Genes: GABRG2
Study 8198935 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27164434 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 27164434 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 25326140 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20057999 — Surrogate Endpoint (SUR): Bone mineral density
Study 30046129 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 19845969 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 9814469 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 7662600 — Surrogate Endpoint (SUR): Blood pressure
Study 23619129 — Surrogate Endpoint (SUR): Blood pressure
Study 21411612 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 21411612 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 27624670 — Surrogate Endpoint (SUR): Serum creatinine
Study 19615130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19615130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10427657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24146170 — Surrogate Endpoint (SUR): Bone mineral density
Study 21348207 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19840533 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19840533 — Surrogate Endpoint (SUR): Blood pressure
Study 18423274 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 18423274 — Surrogate Endpoint (SUR): Blood pressure
Study 25229168 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25229168 — Surrogate Endpoint (SUR): Blood pressure
Study 11475558 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11475558 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31556787 — Predictive Biomarker (PRD): OGG1 mRNA
Genes: OGG1; MMH; MUTM; OGH1
Study 31556787 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 9419752 — Surrogate Endpoint (SUR): Blood pressure
Study 55780 — Surrogate Endpoint (SUR): Blood pressure
Study 26199710 — Surrogate Endpoint (SUR): Blood pressure
Study 25598314 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 21576052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8782125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8782125 — Safety Biomarker (SAF): Hyaluronic acid
Study 29575708 — Surrogate Endpoint (SUR): Blood pressure
Study 20068568 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20068568 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 17331807 — Surrogate Endpoint (SUR): Blood pressure
Study 31902875 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study 31779678 — Surrogate Endpoint (SUR): Blood pressure
Study 25845867 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15017470 — Surrogate Endpoint (SUR): Serum creatinine
Study 31020797 — Surrogate Endpoint (SUR): Blood pressure
Study 21353104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19791551 — Surrogate Endpoint (SUR): Blood pressure
Study 10397685 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22105837 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10529039 — Surrogate Endpoint (SUR): Blood pressure
Study 21058485 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8192170 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 8192170 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8192170 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8464431 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24705391 — Surrogate Endpoint (SUR): Blood pressure
Study 3006449 — Surrogate Endpoint (SUR): Blood pressure
Study 3006449 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30459053 — Surrogate Endpoint (SUR): Blood pressure
Study 24238118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30562785 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22414688 — Surrogate Endpoint (SUR): Blood pressure
Study 18946193 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8537681 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 15023749 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 31475495 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 31475495 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 18636953 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11078240 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11078240 — Surrogate Endpoint (SUR): Blood pressure
Study 1419223 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 22249480 — Surrogate Endpoint (SUR): Blood pressure
Study 7761016 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 7761016 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26212528 — Surrogate Endpoint (SUR): Blood pressure
Study 15370722 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18679038 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 18679038 — Safety Biomarker (SAF): BDNF
Study 27560540 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 20467188 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 16892433 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16892433 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8599991 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8599991 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3931143 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31755872 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21039344 — Predictive Biomarker (PRD): FATE1 mRNA
Genes: FATE1; FATE
Study 9692122 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30075886 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29731620 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 29731620 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25252514 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19673898 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 19673898 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 16020594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16020594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2066773 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27428202 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 27428202 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 27428202 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27428202 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 27428202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16563249 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12172688 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 29979445 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 29979445 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 22446502 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 22446502 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 12833999 — Surrogate Endpoint (SUR): Blood pressure
Study 1284157 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1284157 — Surrogate Endpoint (SUR): Blood pressure
Study 14732734 — Surrogate Endpoint (SUR): Blood pressure
Study 7852749 — Surrogate Endpoint (SUR): Blood pressure
Study 2789428 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31530611 — Surrogate Endpoint (SUR): Pathological complete response
Study 113217 — Surrogate Endpoint (SUR): Blood pressure
Study 19863304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15299099 — Surrogate Endpoint (SUR): Serum creatinine
Study 25188774 — Surrogate Endpoint (SUR): Blood pressure
Study 22024920 — Surrogate Endpoint (SUR): Serum potassium
Study 10205235 — Surrogate Endpoint (SUR): Blood pressure
Study 2222941 — Surrogate Endpoint (SUR): Blood pressure
Study 17666197 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2892881 — Surrogate Endpoint (SUR): Blood pressure
Study 25453534 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 23290142 — Surrogate Endpoint (SUR): Serum creatinine
Study 10488714 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 10488714 — Predictive Biomarker (PRD): Microsatellite instability
Study 8909439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23601452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23601452 — Surrogate Endpoint (SUR): Blood pressure
Study 1699861 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1699861 — Monitoring Biomarker (MOI): HBV DNA
Study 6303793 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study 22428764 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22428764 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18838009 — Surrogate Endpoint (SUR): Blood pressure
Study 16206354 — Surrogate Endpoint (SUR): New morphometric vertebral fractures
Study 12161547 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20011855 — Surrogate Endpoint (SUR): Blood pressure
Study 9506488 — Surrogate Endpoint (SUR): Blood pressure
Study 2855220 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 21783417 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 8385180 — Surrogate Endpoint (SUR): Blood pressure
Study 8385180 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8385180 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11172955 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11172955 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 24499051 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24499051 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 23558760 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20839291 — Surrogate Endpoint (SUR): Bone mineral density
Study 20839291 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12549992 — Surrogate Endpoint (SUR): Blood pressure
Study 31997526 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 30334692 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 21692827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20601389 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20601389 — Surrogate Endpoint (SUR): Blood pressure
Study 10858176 — Predictive Biomarker (PRD): SAGE1 mRNA
Genes: SAGE1; SAGE
Study 19889508 — Surrogate Endpoint (SUR): Blood pressure
Study 18303079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18303079 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10364643 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8770708 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 23990567 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21136163 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31812949 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 31812949 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 31812949 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 22118955 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22118955 — Surrogate Endpoint (SUR): Blood pressure
Study 19758254 — Surrogate Endpoint (SUR): Bacterial count
Study 15339411 — Surrogate Endpoint (SUR): Serum uric acid
Study 29808014 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 24084586 — Surrogate Endpoint (SUR): Blood pressure
Study 22388304 — Surrogate Endpoint (SUR): Blood pressure
Study 19966092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19966092 — Surrogate Endpoint (SUR): Blood pressure
Study 19966092 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19966092 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7861018 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28193797 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22336250 — Predictive Biomarker (PRD): CYBB mRNA
Genes: CYBB; NOX2
Study 19947445 — Surrogate Endpoint (SUR): Blood pressure
Study 19947445 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31912157 — Monitoring Biomarker (MOI): HBV DNA
Study 29074717 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 22090280 — Safety Biomarker (SAF): Nicotinamide phosphoribosyltransferase
Genes: NAMPT; PBEF; PBEF1
Study 19617465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19617465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11596851 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 11596851 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28267480 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26032626 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 18426998 — Surrogate Endpoint (SUR): Blood pressure
Study 12731640 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16084853 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 8565026 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8565026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8565026 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 23562130 — Surrogate Endpoint (SUR): Bone mineral density
Study 23562130 — Predictive Biomarker (PRD): Hormone receptor
Study 19609738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11497201 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9574454 — Predictive Biomarker (PRD): F9 mRNA
Genes: F9
Study 9574454 — Predictive Biomarker (PRD): F12 mRNA
Genes: F12
Study 18327852 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17144553 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 8736458 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3875296 — Surrogate Endpoint (SUR): Blood pressure
Study 3875296 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31502749 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27018153 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 15823285 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 6117309 — Surrogate Endpoint (SUR): Blood pressure
Study 22126282 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22126282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30553130 — Surrogate Endpoint (SUR): Blood pressure
Study 18293124 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15016779 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 15016779 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15016779 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8339853 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23033992 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16111538 — Predictive Biomarker (PRD): HOXA9 mRNA
Genes: HOXA9; HOX1G
Study 1689988 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 22507979 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16054553 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6567715 — Surrogate Endpoint (SUR): Blood pressure
Study 19864449 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19864449 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 16239885 — Surrogate Endpoint (SUR): Serum sodium
Study 24756814 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 20021703 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16096435 — Surrogate Endpoint (SUR): Pathological complete response
Study 9788828 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30848803 — Surrogate Endpoint (SUR): Blood pressure
Study 20004966 — Predictive Biomarker (PRD): CHAF1A mRNA
Genes: CHAF1A; CAF; CAF1P150
Study 20004966 — Predictive Biomarker (PRD): Hormone receptor
Study 17562231 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15160563 — Surrogate Endpoint (SUR): Bone mineral density
Study 11219633 — Surrogate Endpoint (SUR): Blood pressure
Study 9728839 — Surrogate Endpoint (SUR): Blood pressure
Study 21775117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21093036 — Surrogate Endpoint (SUR): Blood pressure
Study 18533779 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 15672113 — Surrogate Endpoint (SUR): Blood pressure
Study 12804845 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10372695 — Surrogate Endpoint (SUR): Bone mineral density
Study 10372695 — Surrogate Endpoint (SUR): Serum testosterone
Study 10829968 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26966919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21537928 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3954933 — Safety Biomarker (SAF): 51Cr-EDTA
Study 25524404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25524404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25524404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10685657 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 9514403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16996860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16996860 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12200684 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 7572320 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7572320 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29477692 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 22156314 — Surrogate Endpoint (SUR): Blood pressure
Study 20167278 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18025879 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10029805 — Predictive Biomarker (PRD): LCK mRNA
Genes: LCK
Study 10526275 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400