TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20739445 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1816218 — Surrogate Endpoint (SUR): Blood pressure
Study 29125915 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 29125915 — Safety Biomarker (SAF): Reactive oxygen species
Study 29125915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 19962986 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A2 mRNA
Genes: SRD5A2
Study 19962986 — Surrogate Endpoint (SUR): Serum testosterone
Study 17121034 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 13679479 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 13679479 — Surrogate Endpoint (SUR): Serum creatinine
Study 13679479 — Surrogate Endpoint (SUR): Blood pressure
Study 10693638 — Surrogate Endpoint (SUR): Serum creatinine
Study 8394847 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31128916 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 15841103 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 15841103 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 11864781 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31423921 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27886020 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27886020 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 27886020 — Safety Biomarker (SAF): BDNF
Study 19998456 — Predictive Biomarker (PRD): CD24 mRNA
Genes: CD24; CD24A
Study 19998456 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study 15708175 — Surrogate Endpoint (SUR): Blood pressure
Study 11998992 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24297687 — Surrogate Endpoint (SUR): Serum potassium
Study 21102210 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12742480 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 12742480 — Surrogate Endpoint (SUR): Serum creatinine
Study 27804067 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 1931399 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 6214264 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31743169 — Surrogate Endpoint (SUR): Blood pressure
Study 30253746 — Surrogate Endpoint (SUR): Blood pressure
Study 17409317 — Surrogate Endpoint (SUR): Blood pressure
Study 8039152 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25744196 — Surrogate Endpoint (SUR): Blood pressure
Study 21327867 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21327867 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 15536458 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 15536458 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15536458 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 15536458 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19091394 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15149346 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14607575 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 14607575 — Surrogate Endpoint (SUR): Blood pressure
Study 14607575 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14607575 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8848411 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30678657 — Predictive Biomarker (PRD): PHLPP2 mRNA
Genes: PHLPP2; KIAA0931; PHLPPL
Study 30678657 — Predictive Biomarker (PRD): BBS9 mRNA
Genes: BBS9; PTHB1
Study 30678657 — Predictive Biomarker (PRD): DUSP4 mRNA
Genes: DUSP4; MKP2; VH2
Study 30678657 — Predictive Biomarker (PRD): HSPA8 mRNA
Genes: HSPA8; HSC70; HSP73; HSPA10
Study 30572163 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 25046949 — Surrogate Endpoint (SUR): Blood pressure
Study 7946588 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 7946588 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20565333 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17689932 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 17689932 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 17689932 — Predictive Biomarker (PRD): CD83 mRNA
Genes: CD83
Study 17689932 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 27266362 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27266362 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 27266362 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 27266362 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27266362 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23474109 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21113612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11231032 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 9855514 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 16763820 — Predictive Biomarker (PRD): SSTR2 mRNA
Genes: SSTR2
Study 18362297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18362297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18362297 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16520053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16520053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12948258 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 16645969 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8840633 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 1458144 — Surrogate Endpoint (SUR): Blood pressure
Study 26803595 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 16258100 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7194063 — Surrogate Endpoint (SUR): Serum uric acid
Study 19526752 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 15668544 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19514 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31031095 — Surrogate Endpoint (SUR): Blood pressure
Study 26330362 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26330362 — Monitoring Biomarker (MOI): HBV DNA
Study 18341678 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18341678 — Surrogate Endpoint (SUR): Blood pressure
Study 8615351 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18596311 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18596311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18596311 — Safety Biomarker (SAF): IL-6 and IL-10
Study 18596311 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1961956 — Surrogate Endpoint (SUR): Blood pressure
Study 7042481 — Surrogate Endpoint (SUR): Blood pressure
Study 11893366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11893366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9916601 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 9916601 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9916601 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 9916601 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 23259702 — Surrogate Endpoint (SUR): Bone mineral density
Study 23259702 — Surrogate Endpoint (SUR): New morphometric vertebral fractures
Study 19054188 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 1619382 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1619382 — Surrogate Endpoint (SUR): Blood pressure
Study 30634657 — Surrogate Endpoint (SUR): Blood pressure
Study 30634657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21570531 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 21570531 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 21570531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21570531 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21570531 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19420019 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16397363 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 15075170 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11157685 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11157685 — Surrogate Endpoint (SUR): Blood pressure
Study 3334056 — Surrogate Endpoint (SUR): Blood pressure
Study 21041839 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 12589396 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 12589396 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 1378156 — Surrogate Endpoint (SUR): Blood pressure
Study 6692648 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 26771913 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 18492416 — Surrogate Endpoint (SUR): Pathological complete response
Study 12923400 — Surrogate Endpoint (SUR): Blood pressure
Study 1443511 — Surrogate Endpoint (SUR): Blood pressure
Study 26329584 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25355484 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11527057 — Surrogate Endpoint (SUR): Bone mineral density
Study 9032647 — Predictive Biomarker (PRD): AGL mRNA
Genes: AGL; GDE
Study 8391569 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8391569 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30876827 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 29957664 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 20878408 — Surrogate Endpoint (SUR): Serum creatinine
Study 15644641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15644641 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 15644641 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15644641 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 7799895 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7799895 — Surrogate Endpoint (SUR): Serum calcium
Study 27038098 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 25351220 — Safety Biomarker (SAF): Hyaluronic acid
Study 20458051 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20458051 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1711250 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 24965569 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 24965569 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 20171420 — Surrogate Endpoint (SUR): Blood pressure
Study 15132403 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15132403 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11298622 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11298622 — Safety Biomarker (SAF): Human leucocyte antigen
Study 11298622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9307639 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20702747 — Surrogate Endpoint (SUR): Blood pressure
Study 6466531 — Surrogate Endpoint (SUR): Serum potassium
Study 31714912 — Surrogate Endpoint (SUR): Serum testosterone
Study 29183257 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 17584828 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 17584828 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16225604 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8638525 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 29231546 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21228609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21228609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21228609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12972896 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 31521118 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 31521118 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 23597156 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23597156 — Surrogate Endpoint (SUR): Blood pressure
Study 20843951 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 20843951 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18841158 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 12541166 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27278477 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 23288353 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23288353 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23288353 — Safety Biomarker (SAF): IL-6 and IL-10
Study 20709569 — Surrogate Endpoint (SUR): Blood pressure
Study 16755160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16755160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24990426 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 15677796 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 15677796 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 15677796 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 1642662 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 26088568 — Surrogate Endpoint (SUR): Blood pressure
Study 25953193 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10634836 — Surrogate Endpoint (SUR): Serum sodium
Study 8859725 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 8859725 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29253154 — Surrogate Endpoint (SUR): Serum testosterone
Study 29253154 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29253154 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29253154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29253154 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26540163 — Surrogate Endpoint (SUR): Blood pressure
Study 14507273 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 1998792 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 21415838 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 21415838 — Surrogate Endpoint (SUR): Blood pressure
Study 8936895 — Predictive Biomarker (PRD): LAX1 mRNA
Genes: LAX1; LAX
Study 8936895 — Predictive Biomarker (PRD): SLC22A4 mRNA
Genes: SLC22A4; ETT; OCTN1; UT2H
Study 8936895 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 30092157 — Surrogate Endpoint (SUR): Bone mineral density
Study 2650730 — Surrogate Endpoint (SUR): Blood pressure
Study 23663287 — Predictive Biomarker (PRD): PPP6R3 mRNA
Genes: PPP6R3; C11orf23; KIAA1558; PP6R3; SAPL; SAPS3
Study 15652899 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21756276 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21756276 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16995327 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 29390298 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19549431 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22305830 — Surrogate Endpoint (SUR): Blood pressure
Study 18222389 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18222389 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 18222389 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 18222389 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 24964348 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 24964348 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17311061 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17311061 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30324895 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 30324895 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 30324895 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31682574 — Surrogate Endpoint (SUR): Blood pressure
Study 15169694 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 25246569 — Predictive Biomarker (PRD): CA3 mRNA
Genes: CA3
Study 22211956 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 30816331 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 26077176 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24717838 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 20643186 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 17013636 — Surrogate Endpoint (SUR): Blood pressure
Study 25826741 — Surrogate Endpoint (SUR): Blood pressure
Study 23404145 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21830407 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 19286361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7611178 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study 29332743 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 27348762 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26756390 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 16605566 — Surrogate Endpoint (SUR): Blood pressure
Study 9802528 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 22362401 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 14725610 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 14725610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11774270 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9419169 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27558280 — Surrogate Endpoint (SUR): Blood pressure
Study 15494274 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study 24895810 — Surrogate Endpoint (SUR): Plasma ammonia
Study 20543666 — Surrogate Endpoint (SUR): Blood pressure
Study 15900355 — Surrogate Endpoint (SUR): Blood pressure
Study 12611560 — Safety Biomarker (SAF): Reactive oxygen species
Study 8897030 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8897030 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 26573456 — Surrogate Endpoint (SUR): Blood pressure
Study 16367882 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12635001 — Surrogate Endpoint (SUR): Blood pressure
Study 23178916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31325962 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 27548249 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 27548249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10732589 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8023589 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8023589 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8023589 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 29211509 — Surrogate Endpoint (SUR): Blood pressure