TrialPanorama/TrialPanorama-database huggingface dataset:
Study 12081158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11544459 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 11544459 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27783213 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 27783213 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27783213 — Surrogate Endpoint (SUR): Blood pressure
Study 23218801 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18316163 — Surrogate Endpoint (SUR): Serum testosterone
Study 9339943 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 9339943 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8416449 — Surrogate Endpoint (SUR): Blood pressure
Study 10326702 — Safety Biomarker (SAF): Interleukin 12
Study 29797109 — Surrogate Endpoint (SUR): Blood pressure
Study 14632722 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 14632722 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1857992 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 29978257 — Surrogate Endpoint (SUR): Bone mineral density
Study 24335695 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 20862944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20862944 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 20862944 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18678300 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12915664 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 16329539 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24465030 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 24465030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12045644 — Surrogate Endpoint (SUR): Blood pressure
Study 19377384 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25097102 — Surrogate Endpoint (SUR): Blood pressure
Study 19890745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12770969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 8862223 — Surrogate Endpoint (SUR): Blood pressure
Study 31265163 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27628617 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 22796581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22796581 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22796581 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15590232 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12149467 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12149467 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28430117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25545400 — Surrogate Endpoint (SUR): Blood pressure
Study 11799385 — Surrogate Endpoint (SUR): Blood pressure
Study 10182195 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7975870 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12225613 — Monitoring Biomarker (MOI): Procalcitonin
Study 30227457 — Surrogate Endpoint (SUR): Blood pressure
Study 24755148 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 22445438 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28296349 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22741260 — Safety Biomarker (SAF): Interleukin 1
Study 15670541 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study 24714360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3858912 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21519151 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17201213 — Surrogate Endpoint (SUR): Blood pressure
Study 10878703 — Surrogate Endpoint (SUR): Blood pressure
Study 2737225 — Surrogate Endpoint (SUR): Blood pressure
Study 2737225 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 28151719 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 28151719 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27132448 — Surrogate Endpoint (SUR): Blood pressure
Study 2376846 — Surrogate Endpoint (SUR): Blood pressure
Study 25752740 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12632615 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12632615 — Surrogate Endpoint (SUR): Blood pressure
Study 30795773 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 30795773 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17569144 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2197046 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 31539077 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31539077 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 27713892 — Surrogate Endpoint (SUR): Blood pressure
Study 24469620 — Surrogate Endpoint (SUR): Blood pressure
Study 30885375 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30885375 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27111221 — Predictive Biomarker (PRD): CHL1 mRNA
Genes: CHL1; CALL
Study 27111221 — Predictive Biomarker (PRD): NELL1 mRNA
Genes: NELL1; NRP1
Study 27111221 — Predictive Biomarker (PRD): GDF1 mRNA
Genes: GDF1
Study 27111221 — Predictive Biomarker (PRD): ARHGEF4 mRNA
Genes: ARHGEF4; KIAA1112
Study 27111221 — Predictive Biomarker (PRD): ITGA4 mRNA
Genes: ITGA4; CD49D
Study 27111221 — Predictive Biomarker (PRD): POLR2B mRNA
Genes: POLR2B
Study 27111221 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 27111221 — Safety Biomarker (SAF): miR-9
Study 27111221 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): miR-124
Study 21219121 — Surrogate Endpoint (SUR): Blood pressure
Study 20648004 — Surrogate Endpoint (SUR): Blood pressure
Study 15127090 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11772908 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11772908 — Surrogate Endpoint (SUR): Blood pressure
Study 29105594 — Surrogate Endpoint (SUR): Total kidney volume
Study 25373834 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23929932 — Surrogate Endpoint (SUR): Serum creatinine
Study 23929932 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 1448789 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27109947 — Surrogate Endpoint (SUR): Serum creatinine
Study 22873531 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15799919 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15755826 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15755826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 6828530 — Surrogate Endpoint (SUR): Blood pressure
Study 21979301 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19712493 — Surrogate Endpoint (SUR): Blood pressure
Study 25108907 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 19202954 — Predictive Biomarker (PRD): ABCD2 mRNA
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study 12920842 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 27463 — Surrogate Endpoint (SUR): Blood pressure
Study 30071142 — Surrogate Endpoint (SUR): Bone mineral density
Study 23358929 — Surrogate Endpoint (SUR): Pathological complete response
Study 9234024 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 29216937 — Surrogate Endpoint (SUR): Blood pressure
Study 9587911 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7912539 — Surrogate Endpoint (SUR): Blood pressure
Study 2645808 — Surrogate Endpoint (SUR): Blood pressure
Study 18444872 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study 12574791 — Surrogate Endpoint (SUR): Blood pressure
Study 25199862 — Surrogate Endpoint (SUR): Probing pocket depth
Study 9459398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9459398 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30427997 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30427997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30427997 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23743804 — Surrogate Endpoint (SUR): Blood pressure
Study 20883456 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 14596683 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 3882125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3882125 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26843092 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20511163 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16426710 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11069364 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8616014 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8616014 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25181492 — Surrogate Endpoint (SUR): Blood pressure
Study 25181492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22112608 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22112608 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9143862 — Surrogate Endpoint (SUR): Blood pressure
Study 8565538 — Safety Biomarker (SAF): Interleukin 1
Study 1827013 — Surrogate Endpoint (SUR): Blood pressure
Study 26264425 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 9059563 — Surrogate Endpoint (SUR): Bone mineral density
Study 23065684 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 18398147 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29763709 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12580941 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 29402752 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 16152828 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16152828 — Safety Biomarker (SAF): Interleukin 12
Study 10100579 — Surrogate Endpoint (SUR): Bone mineral density
Study 10100579 — Surrogate Endpoint (SUR): Serum testosterone
Study 14754569 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 7604802 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31068270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 27817944 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27817944 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17468493 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30135020 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20172704 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17490960 — Surrogate Endpoint (SUR): Blood pressure
Study 31762443 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25886327 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15572894 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11339466 — Surrogate Endpoint (SUR): Blood pressure
Study 2483828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18434722 — Surrogate Endpoint (SUR): Blood pressure
Study 8837186 — Surrogate Endpoint (SUR): Blood pressure
Study 21890793 — Surrogate Endpoint (SUR): Blood pressure
Study 12584831 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 21849081 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 19596586 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17012630 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21080844 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 11158415 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 9550632 — Surrogate Endpoint (SUR): Blood pressure
Study 29344579 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 25850881 — Surrogate Endpoint (SUR): Blood pressure
Study 21242819 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 21242819 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10686961 — Monitoring Biomarker (MOI): Procalcitonin
Study 10686961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10686961 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8662400 — Safety Biomarker (SAF): Interleukin 1
Study 8662400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8662400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8662400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31863809 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 30683137 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 1328366 — Surrogate Endpoint (SUR): Blood pressure
Study 15695780 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 1866057 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 25509255 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 25509255 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7105431 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 8651535 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11498655 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11498655 — Surrogate Endpoint (SUR): Blood pressure
Study 7994449 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 7994449 — Surrogate Endpoint (SUR): Blood pressure
Study 25006405 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25006405 — Surrogate Endpoint (SUR): Blood pressure
Study 21617914 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 12888702 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8314497 — Monitoring Biomarker (MOI): HBV DNA
Study 22093035 — Surrogate Endpoint (SUR): Bone mineral density
Study 21130382 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15576394 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 7623902 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2717986 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 31415033 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 31415033 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 31415033 — Surrogate Endpoint (SUR): Serum creatinine
Study 26116458 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23869233 — Predictive Biomarker (PRD): LIPA mRNA
Genes: LIPA
Study 16461311 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16461311 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16398654 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study 12829196 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10365634 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 8963484 — Surrogate Endpoint (SUR): Serum calcium
Study 21697535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 21697535 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21697535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16229059 — Predictive Biomarker (PRD): GYPC mRNA
Genes: GYPC; GLPC; GPC
Study 16229059 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10869264 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10869264 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10869264 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1413921 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6273009 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31542082 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24600231 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24600231 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17697903 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 9506323 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2525975 — Surrogate Endpoint (SUR): Blood pressure
Study 16312927 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 2073336 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18433946 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18433946 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14513232 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 11320561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 11320561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 24060022 — Surrogate Endpoint (SUR): Bone mineral density
Study 18753749 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 2864936 — Surrogate Endpoint (SUR): Blood pressure
Study 24818590 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 7924784 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7924784 — Surrogate Endpoint (SUR): Blood pressure
Study 20039090 — Monitoring Biomarker (MOI): Procalcitonin
Study 7845310 — Monitoring Biomarker (MOI): HBV DNA
Study 31865785 — Safety Biomarker (SAF): MTHFR
Study 24533792 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 23108883 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 19734176 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 26056191 — Surrogate Endpoint (SUR): Blood pressure
Study 18547692 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 15849842 — Surrogate Endpoint (SUR): Serum triglycerides
Study 12585167 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 12585167 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 12585167 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22692704 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 22692704 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 11503113 — Surrogate Endpoint (SUR): Bone mineral density
Study 9560874 — Surrogate Endpoint (SUR): Blood pressure
Study 24045856 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 20130487 — Surrogate Endpoint (SUR): Blood pressure
Study 9919476 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30626263 — Surrogate Endpoint (SUR): Probing pocket depth
Study 27085343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25616355 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25616355 — Predictive Biomarker (PRD): Hormone receptor
Study 11018567 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26476151 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18413705 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 10911771 — Surrogate Endpoint (SUR): Bone mineral density
Study 27888561 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 26276914 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24108261 — Surrogate Endpoint (SUR): Blood pressure
Study 21368663 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 18199130 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18199130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18199130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14662284 — Predictive Biomarker (PRD): CTNS mRNA
Genes: CTNS
Study 1395760 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1395760 — Surrogate Endpoint (SUR): Blood pressure
Study 28257107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19651872 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19651872 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19651872 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2