TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11011341 — Surrogate Endpoint (SUR): Blood pressure
Study 20884464 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 18447225 — Surrogate Endpoint (SUR): Blood pressure
Study 16390570 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11340886 — Surrogate Endpoint (SUR): Blood pressure
Study 30809967 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 30809967 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30303516 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30303516 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30303516 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27650287 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 20153570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11954880 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 2113611 — Surrogate Endpoint (SUR): Bone mineral density
Study 12620440 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12620440 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9878944 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9878944 — Surrogate Endpoint (SUR): Blood pressure
Study 1902264 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 25998198 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25998198 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23906374 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 21817188 — Safety Biomarker (SAF): Hyaluronic acid
Study 15780528 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 15780528 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31525702 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 24494279 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21555816 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21555816 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17113564 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8583482 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2698570 — Surrogate Endpoint (SUR): Blood pressure
Study 25266246 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25266246 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16110353 — Safety Biomarker (SAF): Reactive oxygen species
Study 16110353 — Surrogate Endpoint (SUR): Sperm parameters
Study 12520750 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2506751 — Surrogate Endpoint (SUR): Blood pressure
Study 31833569 — Surrogate Endpoint (SUR): Blood pressure
Study 2757958 — Surrogate Endpoint (SUR): Blood pressure
Study 31479045 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 31574097 — Surrogate Endpoint (SUR): Bone mineral density
Study 26204844 — Surrogate Endpoint (SUR): Bone mineral density
Study 17394957 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28879445 — Surrogate Endpoint (SUR): Bone mineral density
Study 19415120 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29128692 — Safety Biomarker (SAF): Reactive oxygen species
Study 21814138 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 15488341 — Surrogate Endpoint (SUR): Blood pressure
Study 11681631 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 7524313 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 7524313 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31758375 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 28954802 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 16434457 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 14688031 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11768323 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9390976 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9390976 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27025240 — Predictive Biomarker (PRD): MKRN3 mRNA
Genes: MKRN3; D15S9; RNF63; ZNF127
Study 22980293 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 11527119 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11527119 — Surrogate Endpoint (SUR): Blood pressure
Study 26407272 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 25211490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25211490 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 25211490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25211490 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20465648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 18022044 — Predictive Biomarker (PRD): SCAMP1 mRNA
Genes: SCAMP1; SCAMP
Study 15983242 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12551867 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 24287601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24287601 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22169459 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16170758 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9920062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9920062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7589392 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2123791 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2123791 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31288859 — Predictive Biomarker (PRD): MME mRNA
Genes: MME; EPN
Study 25674699 — Surrogate Endpoint (SUR): Blood pressure
Study 25374269 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1827007 — Surrogate Endpoint (SUR): Blood pressure
Study 1827007 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27623234 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 27623234 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 27623234 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27623234 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 9860093 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study 25881456 — Surrogate Endpoint (SUR): Serum creatinine
Study 21335417 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21335417 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 18570223 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 15593039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15593039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2505631 — Surrogate Endpoint (SUR): Blood pressure
Study 25213566 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 20298497 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28726510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18503840 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 18503840 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 12748498 — Surrogate Endpoint (SUR): Blood pressure
Study 12748498 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10921707 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2485053 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2485053 — Surrogate Endpoint (SUR): Blood pressure
Study 31172685 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 16485522 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 16485522 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 16485522 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19852201 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20701121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8775936 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29121274 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 21592719 — Predictive Biomarker (PRD): ITPA mRNA
Genes: ITPA; C20orf37; My049; OK/SW-cl.9
Study 17979860 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 14717945 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 14717945 — Surrogate Endpoint (SUR): Bone mineral density
Study 9639500 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31855303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31855303 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 31855303 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31855303 — Safety Biomarker (SAF): Interleukin 1
Study 31855303 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31855303 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31855303 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 29620663 — Surrogate Endpoint (SUR): Blood pressure
Study 28963313 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 28963313 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 14698679 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 14698679 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 23743209 — Surrogate Endpoint (SUR): Blood pressure
Study 10381666 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 21246185 — Surrogate Endpoint (SUR): Blood pressure
Study 18471454 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24428467 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 19847185 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 12354701 — Surrogate Endpoint (SUR): Blood pressure
Study 23990660 — Surrogate Endpoint (SUR): Blood pressure
Study 15753500 — Surrogate Endpoint (SUR): Blood pressure
Study 29573038 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 28830365 — Safety Biomarker (SAF): Hyaluronic acid
Study 18330518 — Predictive Biomarker (PRD): RAD1 mRNA
Genes: RAD1; REC1
Study 18330518 — Predictive Biomarker (PRD): FEN1 mRNA
Genes: FEN1; RAD2
Study 17126776 — Surrogate Endpoint (SUR): Blood pressure
Study 7914795 — Surrogate Endpoint (SUR): Blood pressure
Study 9266922 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 1623653 — Surrogate Endpoint (SUR): Blood pressure
Study 6206316 — Surrogate Endpoint (SUR): Serum potassium
Study 6206316 — Surrogate Endpoint (SUR): Serum uric acid
Study 6206316 — Surrogate Endpoint (SUR): Blood pressure
Study 22231705 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22231705 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 17980418 — Predictive Biomarker (PRD): FCER2 mRNA
Genes: FCER2; CD23A; CLEC4J; FCE2; IGEBF
Study 14700510 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12473867 — Surrogate Endpoint (SUR): Blood pressure
Study 9440779 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 19940299 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 19940299 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 14599046 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 26306970 — Surrogate Endpoint (SUR): Serum calcium
Study 2675668 — Surrogate Endpoint (SUR): Serum potassium
Study 788751 — Surrogate Endpoint (SUR): Blood pressure
Study 9400905 — Surrogate Endpoint (SUR): Blood pressure
Study 28872915 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17503753 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27778642 — Predictive Biomarker (PRD): IRS2 mRNA
Genes: IRS2
Study 21480966 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8268648 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24709256 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 15914508 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7913730 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31651843 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31651843 — Safety Biomarker (SAF): BDNF
Study 28692485 — Surrogate Endpoint (SUR): Blood pressure
Study 21508145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21508145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16014759 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27323902 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 27323902 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 27323902 — Predictive Biomarker (PRD): PARP1 mRNA
Genes: PARP1; ADPRT; PPOL
Study 23870160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23870160 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 23870160 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23870160 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23870160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1909052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24142804 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22865782 — Predictive Biomarker (PRD): Hormone receptor
Study 20128336 — Surrogate Endpoint (SUR): Blood pressure
Study 24149180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24149180 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24149180 — Predictive Biomarker (PRD): NRP1 mRNA
Genes: NRP1; NRP; VEGF165R
Study 24149180 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16876497 — Safety Biomarker (SAF): Hyaluronic acid
Study 25499937 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25499937 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18176291 — Surrogate Endpoint (SUR): Serum potassium
Study 12519877 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8777997 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12631097 — Surrogate Endpoint (SUR): Bone mineral density
Study 10570622 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 7633695 — Predictive Biomarker (PRD): SCARA3 mRNA
Genes: SCARA3; CSR
Study 2745343 — Surrogate Endpoint (SUR): Blood pressure
Study 31370154 — Predictive Biomarker (PRD): LANCL2 mRNA
Genes: LANCL2; GPR69B; TASP
Study 28365118 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 23088524 — Safety Biomarker (SAF): Hyaluronic acid
Study 21282661 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 16770728 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7837147 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7837147 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7837147 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 28582279 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28582279 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 28582279 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 12697917 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12697917 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12697917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21867844 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28928170 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9205816 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 23707316 — Predictive Biomarker (PRD): ABCG8 mRNA
Genes: ABCG8
Study 23707316 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 18379356 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16699663 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 3541596 — Surrogate Endpoint (SUR): Blood pressure
Study 29419917 — Surrogate Endpoint (SUR): Blood pressure
Study 22112818 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20694775 — Surrogate Endpoint (SUR): Blood pressure
Study 20694775 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 18471409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27491224 — Surrogate Endpoint (SUR): Blood pressure
Study 21367473 — Surrogate Endpoint (SUR): Blood pressure
Study 16361624 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27509187 — Surrogate Endpoint (SUR): Blood pressure
Study 14551366 — Surrogate Endpoint (SUR): Serum potassium
Study 14551366 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11256554 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9164896 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10999784 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31038442 — Surrogate Endpoint (SUR): Blood pressure
Study 21926186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29348326 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 17074269 — Surrogate Endpoint (SUR): Serum calcium
Study 17074269 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11762560 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 26101276 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26101276 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26101276 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26101276 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17534460 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17534460 — Surrogate Endpoint (SUR): Blood pressure
Study 11588128 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10051942 — Predictive Biomarker (PRD): CSRP3 mRNA
Genes: CSRP3; CLP; MLP
Study 7987837 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31273298 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11477810 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 11477810 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 334436 — Surrogate Endpoint (SUR): Blood pressure
Study 334436 — Surrogate Endpoint (SUR): Serum potassium
Study 18277196 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 6392936 — Surrogate Endpoint (SUR): Blood pressure
Study 22685234 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16208081 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16208081 — Surrogate Endpoint (SUR): Blood pressure
Study 12370850 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 12370850 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 17127227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17127227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25073573 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 20511606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15087034 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 21518460 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15558391 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 26669200 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23234302 — Monitoring Biomarker (MOI): HBV DNA
Study 15734344 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31987998 — Predictive Biomarker (PRD): GSR mRNA
Genes: GSR; GLUR; GRD1
Study 17344507 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10