TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21805607 — Surrogate Endpoint (SUR): Blood pressure
Study 21809989 — Predictive Biomarker (PRD): OTX2 mRNA
Genes: OTX2
Study 21812019 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21812019 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21812736 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 21814460 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21816436 — Predictive Biomarker (PRD): Microsatellite instability
Study 21816790 — Surrogate Endpoint (SUR): Bone mineral density
Study 21816832 — Predictive Biomarker (PRD): GATA2 mRNA
Genes: GATA2
Study 21816833 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 21816912 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 21819438 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21819507 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21819507 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 21819507 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21820136 — Surrogate Endpoint (SUR): Blood pressure
Study 21821014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21821340 — Surrogate Endpoint (SUR): Blood pressure
Study 21823120 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21823912 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 21824458 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 21826527 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21827541 — Surrogate Endpoint (SUR): Blood pressure
Study 21828124 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 21828134 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study 21828134 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study 21828134 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 21828134 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 21828134 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21828134 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 21828134 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 21828134 — Predictive Biomarker (PRD): JAK2
Genes: JTK10
Study 21828141 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21828142 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 21828142 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 21828157 — Surrogate Endpoint (SUR): Blood pressure
Study 21831685 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 21832276 — Surrogate Endpoint (SUR): Platelet count response
Study 21833452 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21833452 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 21835005 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 21836143 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21836147 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21838881 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 21844482 — Surrogate Endpoint (SUR): Blood pressure
Study 21846339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21846636 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21849486 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 21851846 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21851846 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21852114 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 21856867 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 21857286 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21857490 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 21857490 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21859692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21860347 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21860347 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 21862407 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 21862407 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 21865328 — Predictive Biomarker (PRD): AFM mRNA
Genes: AFM; ALB2; ALBA
Study 21865328 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 21865328 — Surrogate Endpoint (SUR): Bone mineral density
Study 21865346 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 21865361 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 21865561 — Predictive Biomarker (PRD): TCN2 mRNA
Genes: TCN2; TC2
Study 21867843 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21868014 — Predictive Biomarker (PRD): ATP2B1 mRNA
Genes: ATP2B1; PMCA1
Study 21868014 — Predictive Biomarker (PRD): DMPK mRNA
Genes: DMPK; DM1PK; MDPK
Study 21868463 — Predictive Biomarker (PRD): TBP mRNA
Genes: TBP; GTF2D1; TF2D; TFIID
Study 21868463 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21868572 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21868778 — Predictive Biomarker (PRD): LGSN mRNA
Genes: LGSN; GLULD1; LGS
Study 21871057 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 21871057 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study 21871057 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21871057 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21873548 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 21873548 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 21876119 — Predictive Biomarker (PRD): BCL11A mRNA
Genes: BCL11A; CTIP1; EVI9; KIAA1809; ZNF856
Study 21876119 — Surrogate Endpoint (SUR): Serum creatinine
Study 21877169 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 21877895 — Predictive Biomarker (PRD): GALNS mRNA
Genes: GALNS
Study 21880642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21880803 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 21880803 — Surrogate Endpoint (SUR): Blood pressure
Study 21883440 — Surrogate Endpoint (SUR): Blood pressure
Study 21884592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21884947 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21884947 — Surrogate Endpoint (SUR): Blood pressure
Study 21885599 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21885601 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 21885725 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21885891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21885891 — Surrogate Endpoint (SUR): Blood pressure
Study 21885891 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21885891 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21889330 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21889574 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21889574 — Safety Biomarker (SAF): BDNF
Study 21890147 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21890643 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 21890643 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 21900113 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21900113 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21900186 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 21900189 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 21901296 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21904575 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21904575 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21904575 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21906204 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21909986 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 21911742 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21911884 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 21912102 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 21913066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21915260 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study 21917607 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 21917625 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21917625 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21917896 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 21917896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21917896 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21920328 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 21921092 — Predictive Biomarker (PRD): FGF7 mRNA
Genes: FGF7; KGF
Study 21926283 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 21931113 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 21931113 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 21931541 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 21931634 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 21931634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21931634 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21931634 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 21933749 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 21933749 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21934446 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21937701 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 21937701 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 21939529 — Surrogate Endpoint (SUR): Blood pressure
Study 21944261 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21945953 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21947381 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21948234 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 21948234 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21953248 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21953248 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21953248 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21956423 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 21956423 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21956423 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21956423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21958326 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21958326 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21960318 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21965374 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21965374 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21965374 — Surrogate Endpoint (SUR): Blood pressure
Study 21966356 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 21966427 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 21969340 — Surrogate Endpoint (SUR): Blood pressure
Study 21969517 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 21974763 — Surrogate Endpoint (SUR): Blood pressure
Study 21976132 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 21976132 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21976540 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21976540 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 21976674 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21982342 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21984804 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21987241 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 21987241 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21989407 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 21991891 — Predictive Biomarker (PRD): GLCCI1 mRNA
Genes: GLCCI1
Study 21991892 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 21993671 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study 21994418 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21994418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21994418 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21994418 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 21994964 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21994964 — Surrogate Endpoint (SUR): Blood pressure
Study 21998698 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 21998698 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21998698 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22002488 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22003071 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22003107 — Predictive Biomarker (PRD): PRPH2 mRNA
Genes: PRPH2; PRPH; RDS; TSPAN22
Study 22003383 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22003383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22003411 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22005144 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 22005709 — Monitoring Biomarker (MOI): Cell-free DNA
Study 22005709 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study 22005912 — Predictive Biomarker (PRD): GSDMB mRNA
Genes: GSDMB; GSDML; PP4052; PRO2521
Study 22006113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22007612 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 22007612 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 22007612 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 22009536 — Predictive Biomarker (PRD): AXIN2 mRNA
Genes: AXIN2
Study 22011297 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 22011297 — Monitoring Biomarker (MOI): HBV DNA
Study 22011459 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22014006 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 22014006 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22016484 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22016786 — Predictive Biomarker (PRD): TRPV4 mRNA
Genes: TRPV4; VRL2; VROAC
Study 22016786 — Surrogate Endpoint (SUR): Blood pressure
Study 22019221 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 22019221 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22019225 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22020850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22021369 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22021722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22021757 — Surrogate Endpoint (SUR): Blood pressure
Study 22022448 — Predictive Biomarker (PRD): TMPRSS13 mRNA
Genes: TMPRSS13; MSP; TMPRSS11
Study 22022448 — Predictive Biomarker (PRD): MCF2 mRNA
Genes: MCF2; DBL
Study 22023158 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22023777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22023777 — Monitoring Biomarker (MOI): Procalcitonin
Study 22023777 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22023777 — Surrogate Endpoint (SUR): Serum creatinine
Study 22024527 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22025196 — Surrogate Endpoint (SUR): Serum testosterone
Study 22025453 — Predictive Biomarker (PRD): PRKRA mRNA
Genes: PRKRA; PACT; RAX; HSD-14; HSD14
Study 22025453 — Predictive Biomarker (PRD): TARBP1 mRNA
Genes: TARBP1; TRM3; TRP185
Study 22025453 — Predictive Biomarker (PRD): TARBP2 mRNA
Genes: TARBP2; TRBP
Study 22025453 — Predictive Biomarker (PRD): AGO2 mRNA
Genes: AGO2; EIF2C2
Study 22025778 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 22025778 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22025778 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22025778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22025778 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22026962 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22028492 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22029910 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22029981 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22030252 — Surrogate Endpoint (SUR): Blood pressure
Study 22031271 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 22033999 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22033999 — Surrogate Endpoint (SUR): Blood pressure
Study 22035573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22036135 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22036135 — Surrogate Endpoint (SUR): Serum uric acid
Study 22036634 — Predictive Biomarker (PRD): SKI mRNA
Genes: SKI
Study 22038064 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 22039246 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 22039246 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 22039246 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 22039493 — Surrogate Endpoint (SUR): Blood pressure
Study 22040109 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22045986 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 22047558 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 22050987 — Surrogate Endpoint (SUR): Serum creatinine
Study 22051930 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22052619 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 22054035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22054035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22054035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22055846 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 22056644 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22057876 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 22057876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22058217 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 22058217 — Surrogate Endpoint (SUR): Minimal residual disease response rate
Study 22058220 — Predictive Biomarker (PRD): DKC1 mRNA
Genes: DKC1; NOLA4
Study 22058220 — Predictive Biomarker (PRD): TINF2 mRNA
Genes: TINF2; TIN2
Study 22068586 — Predictive Biomarker (PRD): ABCA3 mRNA
Genes: ABCA3; ABC3
Study 22068813 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study 22069461 — Surrogate Endpoint (SUR): Blood pressure
Study 22071596 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1