TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02391792 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT03637192 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04636411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01424917 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT04082364 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01564914 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03489148 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00203879 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study NCT02906085 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT03992885 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01250119 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01250119 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01788488 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT00227448 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01355562 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01506258 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01957774 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study NCT01497431 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01763827 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03218332 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03048084 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02317484 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03870100 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT02418429 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT04382300 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02391701 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02391701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02391701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02391701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02835742 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04525352 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04525352 — Predictive Biomarker (PRD): TCIRG1 mRNA
Genes: TCIRG1; ATP6N1C; ATP6V0A3
Study NCT02811809 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02811809 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01141673 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02025322 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00766025 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04213729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03653338 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00027807 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01453361 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00098254 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03323827 — Predictive Biomarker (PRD): SLC25A4 mRNA
Genes: SLC25A4; AAC1; ANT1
Study NCT04505631 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04505631 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03316417 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01457573 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT03599388 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04213482 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03609125 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT04806230 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT04806230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT00890058 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01570296 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01570296 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04192513 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study NCT03786796 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03786796 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03786796 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT03786796 — Predictive Biomarker (PRD): CHEK2 mRNA
Genes: CHEK2; CDS1; CHK2; RAD53
Study NCT03786796 — Predictive Biomarker (PRD): RAD51C mRNA
Genes: RAD51C; RAD51L2
Study NCT03786796 — Predictive Biomarker (PRD): BARD1 mRNA
Genes: BARD1
Study NCT03786796 — Predictive Biomarker (PRD): CHEK1 mRNA
Genes: CHEK1; CHK1
Study NCT03786796 — Predictive Biomarker (PRD): FANCL mRNA
Genes: FANCL; PHF9
Study NCT03786796 — Predictive Biomarker (PRD): RAD51B mRNA
Genes: RAD51B; RAD51L1; REC2
Study NCT02693119 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study NCT01213446 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02051842 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03333304 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT00087789 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04482907 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT04482907 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04482907 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00932126 — Predictive Biomarker (PRD): PAK4 mRNA
Genes: PAK4; KIAA1142
Study NCT00066365 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03944031 — Safety Biomarker (SAF): Beta-N-acetylhexosaminidase
Genes: OGA; HEXC; KIAA0679; MEA5; MGEA5
Study NCT03977584 — Predictive Biomarker (PRD): PSEN1 mRNA
Genes: PSEN1; AD3; PS1; PSNL1
Study NCT03977584 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03344133 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT03344133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02272478 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01754454 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00968864 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03867344 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02233114 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02106975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02106975 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study NCT00400764 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01338103 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00651391 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00651391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00651391 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00651391 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03918148 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03918148 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02187744 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02067130 — Predictive Biomarker (PRD): Liver iron
Study NCT00855673 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00519467 — Predictive Biomarker (PRD): CDA mRNA
Genes: CDA; CDD
Study NCT04603963 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02938156 — Predictive Biomarker (PRD): SHB mRNA
Genes: SHB
Study NCT03766074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03748784 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03625700 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03222453 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study NCT00902889 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00902889 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study NCT01083940 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03851523 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03851523 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00332761 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02393781 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study NCT02178826 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT00999609 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT00999609 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT02212925 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00450255 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02298530 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00981201 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT03543176 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT01358045 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study NCT01358045 — Predictive Biomarker (PRD): Protein patched homolog 1
Genes: PTCH1; PTCH
Study NCT01358045 — Predictive Biomarker (PRD): SMO mRNA
Genes: SMO; SMOH
Study NCT03370965 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT01324479 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00981370 — Predictive Biomarker (PRD): Liver iron
Study NCT03846804 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02535507 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02211079 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02211079 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT02211079 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02211079 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT03708913 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT02462538 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02899364 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT02793219 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00824941 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00242216 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01675791 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT04534283 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study NCT04534283 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT04534283 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT04534283 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01219998 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00413400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03319173 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT00239538 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04607824 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05343156 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05343156 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03616275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02428023 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03925753 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT03925753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03787602 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT03787602 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT00125060 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01360788 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00546104 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT00725374 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT02768415 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04422366 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03476993 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT02997839 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT01930435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01930435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02846584 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03095885 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT01024933 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02899130 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03695744 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT04384783 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study NCT00902083 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02718495 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01596647 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01596647 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01596647 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01596647 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02503579 — Safety Biomarker (SAF): BDNF
Study NCT02540395 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04418713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04418713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04418713 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04641936 — Predictive Biomarker (PRD): TP53INP2 mRNA
Genes: TP53INP2; C20orf110; DOR; PINH
Study NCT00408629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01946165 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT02430818 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02364492 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03084302 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03454087 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03340792 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01821898 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00692640 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study NCT00692640 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00692640 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00303173 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02162758 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study NCT03593096 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04337268 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study NCT02385578 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT03218709 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT04267666 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03840174 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01857856 — Predictive Biomarker (PRD): PLN mRNA
Genes: PLN; PLB
Study NCT01136642 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02144077 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT04261179 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT02141100 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study NCT02141100 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02270788 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT02270788 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT02248701 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03982966 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT00924469 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01362569 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT01362569 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT01362569 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03015090 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT02441946 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02441946 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT02441946 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02441946 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT05264233 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05685823 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT00989261 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00806832 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04549064 — Safety Biomarker (SAF): Amphiregulin
Genes: AREG; AREGB; SDGF
Study NCT04549064 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01345214 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT04493372 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01611090 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT02646657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01170143 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01170143 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT04465110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01380990 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT01380990 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01380990 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT01522248 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01522248 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT03352427 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT01180595 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00617110 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02191137 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02343679 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00144196 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01836627 — Predictive Biomarker (PRD): LAMA2 mRNA
Genes: LAMA2; LAMM
Study NCT01434433 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01521546 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01521546 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04191564 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04516850 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HSD3B1 mRNA
Genes: HSD3B1; 3BH; HSDB3A
Study NCT02581787 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study NCT04188587 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01058655 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01058655 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02436746 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT02507882 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT02507882 — Predictive Biomarker (PRD): IFNL3
Genes: IL-28B; IL28C
Study NCT04626999 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study NCT01617577 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01827956 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1