TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15543337 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11919401 — Surrogate Endpoint (SUR): Serum creatinine
Study 11919401 — Surrogate Endpoint (SUR): Blood pressure
Study 11919401 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7013960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 7013960 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 31907006 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 367976 — Surrogate Endpoint (SUR): Blood pressure
Study 15543464 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 30133324 — Predictive Biomarker (PRD): MYH8 mRNA
Genes: MYH8
Study 23161124 — Surrogate Endpoint (SUR): Blood pressure
Study 18504551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18504551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18504551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31091508 — Surrogate Endpoint (SUR): Blood pressure
Study 28779006 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28779006 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18362931 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18362931 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25018097 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 11448899 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11448899 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 11448899 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 11448899 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11448899 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9602194 — Safety Biomarker (SAF): Interleukin 1
Study 9602194 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7985146 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25700754 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20587052 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 18398094 — Surrogate Endpoint (SUR): Pathological complete response
Study 9284854 — Surrogate Endpoint (SUR): Serum sodium
Study 9284854 — Surrogate Endpoint (SUR): Serum creatinine
Study 12677364 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 29652078 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22378736 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 20349229 — Surrogate Endpoint (SUR): Serum calcium
Study 7869560 — Surrogate Endpoint (SUR): Blood pressure
Study 30844425 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 30844425 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 28440812 — Surrogate Endpoint (SUR): Blood pressure
Study 21031343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21031343 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21031343 — Surrogate Endpoint (SUR): Blood pressure
Study 28505292 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21775113 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18040542 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 7498206 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7498206 — Surrogate Endpoint (SUR): Blood pressure
Study 24636287 — Monitoring Biomarker (MOI): HBV DNA
Study 21790238 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21790238 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 14742994 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8533005 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8533005 — Surrogate Endpoint (SUR): Blood pressure
Study 9836104 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 24471868 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 20799359 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 20799359 — Surrogate Endpoint (SUR): Blood pressure
Study 11285130 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 11285130 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 17378202 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3311619 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18053306 — Surrogate Endpoint (SUR): Blood pressure
Study 17426226 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15083445 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 11535548 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2507747 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study 27737678 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 27737678 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 15943834 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 12528021 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8916980 — Surrogate Endpoint (SUR): Bone mineral density
Study 22506940 — Surrogate Endpoint (SUR): Blood pressure
Study 8675589 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8675589 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2060433 — Surrogate Endpoint (SUR): Blood pressure
Study 6359109 — Surrogate Endpoint (SUR): Blood pressure
Study 23034965 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 23034965 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17963164 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 17963164 — Surrogate Endpoint (SUR): Bone mineral density
Study 12173164 — Surrogate Endpoint (SUR): Blood pressure
Study 10580204 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 29842903 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29842903 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29842903 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11012094 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11012094 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29394348 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29394348 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24719175 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24719175 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24719175 — Predictive Biomarker (PRD): Hormone receptor
Study 24719175 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 15372064 — Surrogate Endpoint (SUR): Blood pressure
Study 12891223 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19583931 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 19583931 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31709997 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 24714530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23664268 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23664268 — Safety Biomarker (SAF): BDNF
Study 16005496 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16005496 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10787444 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10787444 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10419079 — Surrogate Endpoint (SUR): Blood pressure
Study 27761582 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 25867814 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 24565129 — Predictive Biomarker (PRD): EMB mRNA
Genes: EMB
Study 24565129 — Surrogate Endpoint (SUR): Blood pressure
Study 10344353 — Surrogate Endpoint (SUR): Serum creatinine
Study 29880243 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 27498916 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24285251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24285251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16846547 — Surrogate Endpoint (SUR): Blood pressure
Study 1443440 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 1443440 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1443440 — Surrogate Endpoint (SUR): Blood pressure
Study 30266581 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 29562659 — Surrogate Endpoint (SUR): Blood pressure
Study 25304296 — Surrogate Endpoint (SUR): Blood pressure
Study 22405352 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15664241 — Monitoring Biomarker (MOI): HBV DNA
Study 7580637 — Surrogate Endpoint (SUR): Blood pressure
Study 6766731 — Surrogate Endpoint (SUR): Blood pressure
Study 20035395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20035395 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17122108 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11060137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3929874 — Surrogate Endpoint (SUR): Blood pressure
Study 25191771 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 17301956 — Pharmacodynamic Biomarker (PDY): Retinoblastoma-associated protein
Genes: RB1
Study 2972162 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 28115329 — Surrogate Endpoint (SUR): Serum creatinine
Study 24378148 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 17429754 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11131082 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 9364249 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 9364249 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 15498091 — Surrogate Endpoint (SUR): Blood pressure
Study 23150906 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 21423852 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21126997 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12911449 — Surrogate Endpoint (SUR): Bone mineral density
Study 12911449 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12911449 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8444274 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 30453487 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20400411 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8633817 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27267950 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 9808644 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9808644 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7631621 — Surrogate Endpoint (SUR): Blood pressure
Study 31305270 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22730040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22730040 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22730040 — Safety Biomarker (SAF): BDNF
Study 8932964 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1989742 — Surrogate Endpoint (SUR): Blood pressure
Study 31313021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31313021 — Monitoring Biomarker (MOI): Cell-free DNA
Study 25560571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25560571 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20863217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20863217 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18195111 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 18195111 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 15928933 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1915209 — Surrogate Endpoint (SUR): Blood pressure
Study 19743466 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 11118067 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31362785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31362785 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31362785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31362785 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 31362785 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 10210340 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study 1905474 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1905474 — Surrogate Endpoint (SUR): Serum triglycerides
Study 27857189 — Predictive Biomarker (PRD): KCNQ1 mRNA
Genes: KCNQ1; KCNA8; KCNA9; KVLQT1
Study 24075865 — Predictive Biomarker (PRD): VIT mRNA
Genes: VIT; UNQ647/PRO1277
Study 20082624 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 10915227 — Surrogate Endpoint (SUR): Blood pressure
Study 24811095 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 7843758 — Surrogate Endpoint (SUR): Blood pressure
Study 406627 — Surrogate Endpoint (SUR): Blood pressure
Study 30379568 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28802596 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 28802596 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 12680858 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 15147076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19435959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19435959 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17898698 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17112804 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 17112804 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 17112804 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 17112804 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 28302271 — Surrogate Endpoint (SUR): Serum creatinine
Study 12906063 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12906063 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10562579 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 10562579 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 6351988 — Surrogate Endpoint (SUR): Serum testosterone
Study 22944060 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22944060 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22944060 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20710084 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 11915378 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 31788995 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31788995 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 31788995 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 23141780 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 12745614 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 1329477 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22274951 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19099009 — Surrogate Endpoint (SUR): Blood pressure
Study 9430449 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 31666688 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30354399 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 30354399 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22931620 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22931620 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17240625 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 17240625 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 17240625 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17240625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17240625 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 8861742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8861742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1703769 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 23356210 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 23356210 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 18196620 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12143454 — Surrogate Endpoint (SUR): Blood pressure
Study 30285092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20458441 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22708798 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 22708798 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21698545 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10216089 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 28457318 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20647959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16435613 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10588996 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 8948369 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9402176 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study 9402176 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9402176 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24996416 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16184439 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 12637464 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8931083 — Surrogate Endpoint (SUR): Blood pressure
Study 21364487 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23331844 — Surrogate Endpoint (SUR): Serum testosterone
Study 21241828 — Surrogate Endpoint (SUR): Blood pressure
Study 16042028 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 18278987 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 1714018 — Surrogate Endpoint (SUR): Blood pressure
Study 20235087 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 16091636 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26884344 — Predictive Biomarker (PRD): GAPDH mRNA
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 26884344 — Predictive Biomarker (PRD): ACTB mRNA
Genes: ACTB
Study 26884344 — Predictive Biomarker (PRD): RPLP0 mRNA
Genes: RPLP0
Study 26884344 — Predictive Biomarker (PRD): IGF1R mRNA
Genes: IGF1R
Study 26884344 — Safety Biomarker (SAF): Amphiregulin
Genes: AREG; AREGB; SDGF
Study 15136218 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8094114 — Surrogate Endpoint (SUR): Serum creatinine
Study 29373476 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29373476 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 26395174 — Surrogate Endpoint (SUR): Blood pressure
Study 8863236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1321655 — Surrogate Endpoint (SUR): Blood pressure
Study 3453169 — Surrogate Endpoint (SUR): Blood pressure
Study 30169969 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 22851700 — Surrogate Endpoint (SUR): Serum creatinine
Study 18427418 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7562679 — Surrogate Endpoint (SUR): Blood pressure
Study 7562679 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20552094 — Predictive Biomarker (PRD): CPE mRNA
Genes: CPE