TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30664075 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12782545 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12782545 — Surrogate Endpoint (SUR): Blood pressure
Study 11243632 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20433527 — Surrogate Endpoint (SUR): Blood pressure
Study 16202859 — Surrogate Endpoint (SUR): Blood pressure
Study 24099141 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21756768 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 18283261 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 18283261 — Predictive Biomarker (PRD): FER mRNA
Genes: FER; TYK3
Study 18283261 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 26636929 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 26636929 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26636929 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25237065 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 25237065 — Predictive Biomarker (PRD): IGFBP7 mRNA
Genes: IGFBP7; MAC25; PSF
Study 12702905 — Monitoring Biomarker (MOI): HBV DNA
Study 30200935 — Surrogate Endpoint (SUR): Blood pressure
Study 24984178 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 24984178 — Surrogate Endpoint (SUR): Blood pressure
Study 20227347 — Surrogate Endpoint (SUR): Blood pressure
Study 8926014 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8926014 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 1905495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1905495 — Safety Biomarker (SAF): Interleukin 1
Study 1905495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23059701 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 17895912 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17895912 — Surrogate Endpoint (SUR): Blood pressure
Study 25761367 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 18587236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18587236 — Safety Biomarker (SAF): MTHFR
Study 8027279 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 21840164 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 31970675 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 10548673 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 31041358 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18397688 — Surrogate Endpoint (SUR): Serum creatinine
Study 31116180 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 26760174 — Safety Biomarker (SAF): Nicotinamide phosphoribosyltransferase
Genes: NAMPT; PBEF; PBEF1
Study 26760174 — Predictive Biomarker (PRD): SIRT3 mRNA
Genes: SIRT3; SIR2L3
Study 26760174 — Predictive Biomarker (PRD): SIRT7 mRNA
Genes: SIRT7; SIR2L7
Study 22136516 — Surrogate Endpoint (SUR): Blood pressure
Study 2335101 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 26119226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17470858 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17470858 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9808597 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19757993 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11678828 — Predictive Biomarker (PRD): Hormone receptor
Study 9252944 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9252944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8517932 — Surrogate Endpoint (SUR): Blood pressure
Study 25073008 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 15701468 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15701468 — Surrogate Endpoint (SUR): Blood pressure
Study 10087722 — Surrogate Endpoint (SUR): Blood pressure
Study 1971586 — Surrogate Endpoint (SUR): Blood pressure
Study 24186866 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24186866 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11687463 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 31157360 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 27748563 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 22056247 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22056247 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19560810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17710801 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11803060 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 6941670 — Surrogate Endpoint (SUR): Blood pressure
Study 24062200 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20416218 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20416218 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1909469 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 6874179 — Surrogate Endpoint (SUR): Blood pressure
Study 18372696 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12207074 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12207074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 4103277 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 28262603 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29862410 — Surrogate Endpoint (SUR): Blood pressure
Study 29862410 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29862410 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7854612 — Surrogate Endpoint (SUR): Blood pressure
Study 31326319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31326319 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21788316 — Surrogate Endpoint (SUR): Serum sodium
Study 19090788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3046332 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21569012 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 29108938 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20456291 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16647412 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 16647412 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16647412 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27134522 — Surrogate Endpoint (SUR): Serum creatinine
Study 17469045 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12575338 — Surrogate Endpoint (SUR): Blood pressure
Study 7641744 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31707829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15645323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28950430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28298244 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 17388233 — Surrogate Endpoint (SUR): Blood pressure
Study 7353381 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 19622592 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 15100507 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9643140 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8134075 — Surrogate Endpoint (SUR): Blood pressure
Study 16505417 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10551494 — Predictive Biomarker (PRD): EEF2 mRNA
Genes: EEF2; EF2
Study 10551494 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 1653362 — Pharmacodynamic Biomarker (PDY): DNA topoisomerase I
Genes: TOP1
Study 24878629 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 9593779 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23492671 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9349340 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9349340 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10565560 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 10565560 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24761313 — Predictive Biomarker (PRD): NAT8 mRNA
Genes: NAT8; CML1; GLA; TSC501
Study 17560421 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 4065432 — Surrogate Endpoint (SUR): Blood pressure
Study 10941887 — Surrogate Endpoint (SUR): Bone mineral density
Study 8937760 — Safety Biomarker (SAF): Beta-N-acetylhexosaminidase
Genes: OGA; HEXC; KIAA0679; MEA5; MGEA5
Study 29222891 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11676992 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 30202927 — Surrogate Endpoint (SUR): Blood pressure
Study 27283332 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1951871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1951871 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 31719552 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31719552 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 15795697 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 15530692 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22925988 — Surrogate Endpoint (SUR): Blood pressure
Study 9578254 — Safety Biomarker (SAF): Hyaluronic acid
Study 23204152 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 18599016 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 10091407 — Predictive Biomarker (PRD): TAL1 mRNA
Genes: TAL1; BHLHA17; SCL; TCL5
Study 10091407 — Predictive Biomarker (PRD): Microsatellite instability
Study 31229501 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 31229501 — Predictive Biomarker (PRD): COL17A1 mRNA
Genes: COL17A1; BP180; BPAG2
Study 31229501 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 22549948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22549948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24360178 — Surrogate Endpoint (SUR): Blood pressure
Study 19912686 — Monitoring Biomarker (MOI): HBV DNA
Study 15499535 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6152280 — Surrogate Endpoint (SUR): Blood pressure
Study 22951019 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 8864793 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 8864793 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 8864793 — Surrogate Endpoint (SUR): Blood pressure
Study 8864793 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1625490 — Predictive Biomarker (PRD): POMP mRNA
Genes: POMP; C13orf12; UMP1; HSPC014; HSPC036; PNAS-110
Study 22781456 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22781456 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 22781456 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19732126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19732126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19732126 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 19732126 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19732126 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25880761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25880761 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 25880761 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23469933 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21613358 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 21613358 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8024947 — Surrogate Endpoint (SUR): Blood pressure
Study 18838526 — Surrogate Endpoint (SUR): Blood pressure
Study 9177881 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8104509 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 2425168 — Surrogate Endpoint (SUR): Blood pressure
Study 29561783 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 24533064 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23052711 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 23052711 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23052711 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 23052711 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 18504215 — Surrogate Endpoint (SUR): Blood pressure
Study 20014600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17470271 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24376274 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 24376274 — Surrogate Endpoint (SUR): Serum calcium
Study 24376274 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20506062 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 20506062 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 1722443 — Surrogate Endpoint (SUR): Serum calcium
Study 30823945 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 25302456 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19363437 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19363437 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10498596 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31930894 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 16499887 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 11428472 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11428472 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30789633 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 28222379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21593803 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 21593803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21593803 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21593803 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21593803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16792608 — Surrogate Endpoint (SUR): Blood pressure
Study 12505224 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12505224 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7792558 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25926252 — Surrogate Endpoint (SUR): Blood pressure
Study 18342398 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 11115698 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11115698 — Monitoring Biomarker (MOI): HBV DNA
Study 30693609 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22962427 — Surrogate Endpoint (SUR): Blood pressure
Study 10355396 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 24475821 — Predictive Biomarker (PRD): CBR1 mRNA
Genes: CBR1; CBR; CRN; SDR21C1
Study 8150527 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2971619 — Surrogate Endpoint (SUR): Blood pressure
Study 25216510 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 25216510 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 25216510 — Surrogate Endpoint (SUR): Blood pressure
Study 3282261 — Surrogate Endpoint (SUR): Blood pressure
Study 19176272 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7640931 — Surrogate Endpoint (SUR): Bone mineral density
Study 17898169 — Predictive Biomarker (PRD): CLCA1 mRNA
Genes: CLCA1; CACC1
Study 17898169 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FKBP5 mRNA
Genes: FKBP5; AIG6; FKBP51
Study 30219433 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30219433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30317548 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Neurofilament light polypeptide
Genes: NEFL; NF68; NFL
Study 8134155 — Surrogate Endpoint (SUR): Serum calcium
Study 19058685 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 9057069 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29653636 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24238783 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 9586908 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 9586908 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 9586908 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 36250 — Surrogate Endpoint (SUR): Blood pressure
Study 17515020 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30342058 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15791376 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15791376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9071482 — Surrogate Endpoint (SUR): Bone mineral density
Study 29365351 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29365351 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10323386 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26751016 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26751016 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 26751016 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26751016 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15354105 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25791513 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15588037 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 3311571 — Surrogate Endpoint (SUR): Blood pressure
Study 31843232 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29602978 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 27825638 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 27825638 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27825638 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 27825638 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 27825638 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 12755841 — Surrogate Endpoint (SUR): Serum creatinine
Study 25514303 — Surrogate Endpoint (SUR): Blood pressure
Study 25514303 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25514303 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22462635 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 18683786 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 18683786 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 18683786 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 26552756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19386052 — Surrogate Endpoint (SUR): Blood pressure
Study 15203432 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16634738 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS