TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19836626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19836626 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19836626 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31266826 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 19734628 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 17634482 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17634482 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9144027 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2831788 — Surrogate Endpoint (SUR): Blood pressure
Study 2831788 — Surrogate Endpoint (SUR): Serum potassium
Study 15016559 — Surrogate Endpoint (SUR): Blood pressure
Study 1081905 — Predictive Biomarker (PRD): PRCP mRNA
Genes: PRCP; PCP
Study 24482301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24482301 — Safety Biomarker (SAF): Interleukin 12
Study 22677045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7712689 — Surrogate Endpoint (SUR): Blood pressure
Study 309031 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25842727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23926681 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8021909 — Surrogate Endpoint (SUR): Blood pressure
Study 9300474 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 9300474 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 29929437 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18392039 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 10807619 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8806933 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10475317 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10475317 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 10475317 — Surrogate Endpoint (SUR): Blood pressure
Study 10467840 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 540702 — Surrogate Endpoint (SUR): Blood pressure
Study 30799401 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 17557990 — Surrogate Endpoint (SUR): Blood pressure
Study 8535099 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8535099 — Surrogate Endpoint (SUR): Blood pressure
Study 28430910 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17485449 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19939481 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19181821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19181821 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8845664 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 334217 — Surrogate Endpoint (SUR): Blood pressure
Study 24226492 — Surrogate Endpoint (SUR): Blood pressure
Study 29773326 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 27940181 — Surrogate Endpoint (SUR): Blood pressure
Study 6283753 — Surrogate Endpoint (SUR): Blood pressure
Study 19363607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15520323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29710042 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29710042 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26704028 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 18164894 — Surrogate Endpoint (SUR): Blood pressure
Study 12714026 — Surrogate Endpoint (SUR): Blood pressure
Study 11091497 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 11091497 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8925996 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16170182 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11994348 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24783926 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 19933120 — Surrogate Endpoint (SUR): Blood pressure
Study 18482026 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 11470150 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 11470150 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9604591 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 2544249 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 2544249 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 2544249 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 23240909 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 15450558 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7529155 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7529155 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 7529155 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 23481666 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23481666 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 19781316 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19781316 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17206703 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11238498 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11238498 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11238498 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11238498 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3245292 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29466682 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29466682 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 15679716 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 15679716 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12887127 — Surrogate Endpoint (SUR): Blood pressure
Study 10365610 — Surrogate Endpoint (SUR): Blood pressure
Study 31823654 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 27450438 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 27450438 — Safety Biomarker (SAF): BDNF
Study 24188894 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 24188894 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24188894 — Surrogate Endpoint (SUR): Blood pressure
Study 17255277 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 17255277 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 15767638 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 15767638 — Predictive Biomarker (PRD): Hormone receptor
Study 1858160 — Surrogate Endpoint (SUR): Serum creatinine
Study 30940012 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 5472756 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27320903 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 23980090 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20881867 — Surrogate Endpoint (SUR): Blood pressure
Study 16845347 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 27575731 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27575731 — Safety Biomarker (SAF): Cyclin-dependent kinase inhibitor 1
Genes: CDKN1A
Study 12429856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12429856 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12429856 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10518249 — Surrogate Endpoint (SUR): Serum creatinine
Study 30591959 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30591959 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27984535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27984535 — Safety Biomarker (SAF): IL-6 and IL-10
Study 20603439 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 18318099 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 15965673 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 11988609 — Surrogate Endpoint (SUR): Blood pressure
Study 7625342 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7625342 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23760009 — Surrogate Endpoint (SUR): Blood pressure
Study 23760009 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19487381 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28606084 — Surrogate Endpoint (SUR): Blood pressure
Study 28606084 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28606084 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28606084 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20885188 — Surrogate Endpoint (SUR): Blood pressure
Study 15894775 — Surrogate Endpoint (SUR): Serum creatinine
Study 1462882 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17870203 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 17870203 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17870203 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14666763 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9064258 — Predictive Biomarker (PRD): PTPRC
Genes: LCA; T200; GP180
Study 9064258 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 9064258 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 22997787 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 17521315 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 17521315 — Safety Biomarker (SAF): Cytochrome c
Study 18761816 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 18761816 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18761816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12595863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12595863 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1693042 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 23365108 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 19389471 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 19389471 — Safety Biomarker (SAF): Reactive oxygen species
Study 27974055 — Safety Biomarker (SAF): 51Cr-EDTA
Study 23523116 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 2389649 — Surrogate Endpoint (SUR): Blood pressure
Study 26912555 — Surrogate Endpoint (SUR): Total kidney volume
Study 18852339 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18852339 — Predictive Biomarker (PRD): CD209 mRNA
Genes: CD209; CLEC4L
Study 8973753 — Surrogate Endpoint (SUR): Blood pressure
Study 8973753 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 29037769 — Predictive Biomarker (PRD): DIAPH2 mRNA
Genes: DIAPH2; DIA
Study 22719060 — Surrogate Endpoint (SUR): Blood pressure
Study 20150526 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26121432 — Safety Biomarker (SAF): Clusterin
Genes: CLU; APOJ; CLI; KUB1; AAG4
Study 25270214 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study 25270214 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 25270214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25270214 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25270214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25270214 — Safety Biomarker (SAF): Reactive oxygen species
Study 2452997 — Surrogate Endpoint (SUR): Blood pressure
Study 30830474 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 30474426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29761211 — Safety Biomarker (SAF): Hyaluronic acid
Study 28780563 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24565712 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15345738 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 27678438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27678438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27678438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21937526 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 21937526 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 15885167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15885167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15885167 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15885167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2277475 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 396083 — Surrogate Endpoint (SUR): Blood pressure
Study 396083 — Surrogate Endpoint (SUR): Serum uric acid
Study 19661450 — Surrogate Endpoint (SUR): Blood pressure
Study 8013155 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 30758314 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 22999988 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 12689610 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 6754131 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18414202 — Predictive Biomarker (PRD): PNKP mRNA
Genes: PNKP
Study 12493339 — Surrogate Endpoint (SUR): Blood pressure
Study 17026489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15576973 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2646619 — Surrogate Endpoint (SUR): Blood pressure
Study 30270543 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27720273 — Surrogate Endpoint (SUR): Blood pressure
Study 27720273 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27720273 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15492764 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 15492764 — Safety Biomarker (SAF): DRD2
Study 22834565 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19278806 — Surrogate Endpoint (SUR): Blood pressure
Study 9329702 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 27169838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20613459 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28000468 — Surrogate Endpoint (SUR): Blood pressure
Study 23916935 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23916935 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6138939 — Surrogate Endpoint (SUR): Serum potassium
Study 6138939 — Surrogate Endpoint (SUR): Serum triglycerides
Study 6138939 — Surrogate Endpoint (SUR): Blood pressure
Study 26164621 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 12645718 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12645718 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11057406 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 8966497 — Surrogate Endpoint (SUR): Bone mineral density
Study 31208943 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 31208943 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 28753851 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 28753851 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 20218940 — Surrogate Endpoint (SUR): Blood pressure
Study 12354129 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 12354129 — Surrogate Endpoint (SUR): Blood pressure
Study 12354129 — Surrogate Endpoint (SUR): Urine free cortisol
Study 15857327 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15857327 — Surrogate Endpoint (SUR): Blood pressure
Study 10847255 — Surrogate Endpoint (SUR): Blood pressure
Study 6392119 — Surrogate Endpoint (SUR): Blood pressure
Study 22666496 — Predictive Biomarker (PRD): DNAJC5B mRNA
Genes: DNAJC5B; CSPBETA
Study 18508833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15889132 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 17002927 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 10807748 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 8285776 — Surrogate Endpoint (SUR): Blood pressure
Study 22878749 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12688625 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 2407957 — Surrogate Endpoint (SUR): Bone mineral density
Study 31500588 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22552034 — Surrogate Endpoint (SUR): Blood pressure
Study 16325696 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 30949182 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30949182 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 30949182 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 30949182 — Predictive Biomarker (PRD): KLRC2 mRNA
Genes: KLRC2; NKG2C
Study 27119829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9540144 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8062609 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8062609 — Safety Biomarker (SAF): Urinary microalbumin
Study 8062609 — Surrogate Endpoint (SUR): Serum creatinine
Study 8062609 — Surrogate Endpoint (SUR): Blood pressure
Study 2643042 — Surrogate Endpoint (SUR): Serum creatinine
Study 31175814 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 25387489 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23352954 — Surrogate Endpoint (SUR): Bone mineral density
Study 7824963 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 27012822 — Surrogate Endpoint (SUR): Blood pressure
Study 18728054 — Surrogate Endpoint (SUR): Blood pressure
Study 15243282 — Surrogate Endpoint (SUR): Bone mineral density
Study 31649376 — Predictive Biomarker (PRD): INHBA mRNA
Genes: INHBA
Study 31649376 — Predictive Biomarker (PRD): ACVR2B mRNA
Genes: ACVR2B
Study 31649376 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 31649376 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 31649376 — Predictive Biomarker (PRD): GDF10 mRNA
Genes: GDF10; BMP3B
Study 31649376 — Safety Biomarker (SAF): C-X-C motif chemokine 5
Genes: CXCL5; ENA78; SCYB5
Study 31649376 — Predictive Biomarker (PRD): FGF2 mRNA
Genes: FGF2; FGFB
Study 31649376 — Predictive Biomarker (PRD): FGF12 mRNA
Genes: FGF12; FGF12B; FHF1
Study 31649376 — Predictive Biomarker (PRD): OLR1 mRNA
Genes: OLR1; CLEC8A; LOX1
Study 31649376 — Predictive Biomarker (PRD): MMP13 mRNA
Genes: MMP13
Study 31649376 — Predictive Biomarker (PRD): IL23A mRNA
Genes: IL23A; SGRF; UNQ2498/PRO5798
Study 22056854 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17258146 — Surrogate Endpoint (SUR): Bone mineral density
Study 15059509 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 12042982 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 12042982 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25739031 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10676676 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16556241 — Predictive Biomarker (PRD): GDNF mRNA
Genes: GDNF
Study 14636820 — Surrogate Endpoint (SUR): Blood pressure
Study 16995862 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9715184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6817772 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26628415 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 10023503 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 8522632 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2401129 — Surrogate Endpoint (SUR): Blood pressure
Study 2401129 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2401129 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31273763 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS