TrialPanorama/TrialPanorama-database huggingface dataset:
Study 9208337 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9208337 — Surrogate Endpoint (SUR): Blood pressure
Study 3794134 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14505773 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8466682 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8466682 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 1776803 — Safety Biomarker (SAF): Protein AMBP
Genes: AMBP; HCP; ITIL
Study 1776803 — Surrogate Endpoint (SUR): Blood pressure
Study 6132524 — Surrogate Endpoint (SUR): Blood pressure
Study 28267790 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24387157 — Surrogate Endpoint (SUR): Blood pressure
Study 25386736 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25386736 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 25386736 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 17371783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15726550 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 12238905 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12238905 — Surrogate Endpoint (SUR): Blood pressure
Study 28682837 — Surrogate Endpoint (SUR): Blood pressure
Study 25504576 — Predictive Biomarker (PRD): SIRT3 mRNA
Genes: SIRT3; SIR2L3
Study 25504576 — Safety Biomarker (SAF): Reactive oxygen species
Study 22848080 — Surrogate Endpoint (SUR): Blood pressure
Study 9987698 — Surrogate Endpoint (SUR): Blood pressure
Study 7351286 — Surrogate Endpoint (SUR): Serum calcium
Study 31152080 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31152080 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31152080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28591543 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 15291499 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15291499 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11414349 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 11414349 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 15277374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15277374 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8215672 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 29897544 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22493913 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31711229 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 31261732 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 29036790 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29036790 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 29036790 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22938928 — Surrogate Endpoint (SUR): Bone mineral density
Study 19445546 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17855758 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 11336083 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11336083 — Surrogate Endpoint (SUR): Blood pressure
Study 9660431 — Surrogate Endpoint (SUR): Bone mineral density
Study 9660431 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9660431 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15254883 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2490828 — Surrogate Endpoint (SUR): Blood pressure
Study 1649840 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30262155 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 27495137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19845991 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 15701187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8314427 — Surrogate Endpoint (SUR): Blood pressure
Study 26545320 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 1709239 — Surrogate Endpoint (SUR): Serum potassium
Study 20044312 — Surrogate Endpoint (SUR): Blood pressure
Study 16014046 — Surrogate Endpoint (SUR): Blood pressure
Study 19561014 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 17555006 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15811355 — Surrogate Endpoint (SUR): Blood pressure
Study 23410714 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23410714 — Surrogate Endpoint (SUR): Blood pressure
Study 14759591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14759591 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 14759591 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 14759591 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 2408425 — Surrogate Endpoint (SUR): Blood pressure
Study 27379625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8584384 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 7682927 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 19289931 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19289931 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30256215 — Surrogate Endpoint (SUR): Blood pressure
Study 22410389 — Surrogate Endpoint (SUR): Blood pressure
Study 20307903 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 20307903 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22349543 — Predictive Biomarker (PRD): LHB mRNA
Genes: LHB
Study 8925521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8925521 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8925521 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19510 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 25001274 — Surrogate Endpoint (SUR): Blood pressure
Study 21734423 — Predictive Biomarker (PRD): SH2D1A mRNA
Genes: SH2D1A; DSHP; SAP
Study 8653995 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 8653995 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP2C19
Genes: P450IIC19; CPCJ
Study 22325086 — Surrogate Endpoint (SUR): Blood pressure
Study 9552059 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 15390234 — Safety Biomarker (SAF): Reactive oxygen species
Study 1097143 — Surrogate Endpoint (SUR): Serum potassium
Study 28407660 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15248139 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15248139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24803523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24803523 — Safety Biomarker (SAF): IL-6 and IL-10
Study 23474997 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 15374554 — Surrogate Endpoint (SUR): Blood pressure
Study 9431832 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 3545744 — Surrogate Endpoint (SUR): Blood pressure
Study 26886716 — Surrogate Endpoint (SUR): Serum hemoglobin A1C
Study 18457248 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18457248 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 18457248 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12229307 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7915989 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19392579 — Surrogate Endpoint (SUR): Blood pressure
Study 10602349 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8621850 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 29524000 — Predictive Biomarker (PRD): SLC2A2 mRNA
Genes: SLC2A2; GLUT2
Study 29441909 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24081158 — Predictive Biomarker (PRD): COL1A1 mRNA
Genes: COL1A1
Study 24081158 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 31799993 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 25248345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25248345 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21883001 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9791144 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9791144 — Surrogate Endpoint (SUR): Blood pressure
Study 27099247 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 22516692 — Predictive Biomarker (PRD): MCTS1 mRNA
Genes: MCTS1; MCT1
Study 20444742 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8973709 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 1282179 — Surrogate Endpoint (SUR): Blood pressure
Study 20536366 — Surrogate Endpoint (SUR): Serum creatinine
Study 2994386 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15883262 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9607039 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 7649608 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 23483198 — Safety Biomarker (SAF): DRD3
Study 21993434 — Surrogate Endpoint (SUR): Blood pressure
Study 16563397 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 3886023 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 12374512 — Surrogate Endpoint (SUR): Blood pressure
Study 30499618 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 30499618 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 21779819 — Surrogate Endpoint (SUR): Bone mineral density
Study 15826746 — Surrogate Endpoint (SUR): Bone mineral density
Study 8199810 — Surrogate Endpoint (SUR): Serum potassium
Study 8199810 — Surrogate Endpoint (SUR): Blood pressure
Study 31874497 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 31874497 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 31874497 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31874497 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31874497 — Predictive Biomarker (PRD): OPRD1 mRNA
Genes: OPRD1; OPRD
Study 31874497 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 31874497 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 31874497 — Predictive Biomarker (PRD): P2RY12 mRNA
Genes: P2RY12; HORK3
Study 16115337 — Predictive Biomarker (PRD): IPP mRNA
Genes: IPP; KLHL27
Study 16115337 — Surrogate Endpoint (SUR): Blood pressure
Study 16115337 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 3896455 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9279722 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27351217 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 25189213 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23775961 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31736187 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 31736187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31736187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31736187 — Safety Biomarker (SAF): Interleukin 1
Study 27221874 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24262967 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 24262967 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24262967 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 7897158 — Safety Biomarker (SAF): Interleukin 1
Study 7897158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7897158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15316750 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 11172188 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19543808 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28207554 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17086503 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 15483784 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 7888537 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31200019 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 8275621 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28681988 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 18795912 — Surrogate Endpoint (SUR): Bone mineral density
Study 26152773 — Surrogate Endpoint (SUR): Blood pressure
Study 8908222 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20195266 — Predictive Biomarker (PRD): PRKAR2B mRNA
Genes: PRKAR2B
Study 20195266 — Predictive Biomarker (PRD): ADGRV1 mRNA
Genes: ADGRV1; GPR98; KIAA0686; KIAA1943; MASS1; VLGR1
Study 20195266 — Predictive Biomarker (PRD): FMNL3 mRNA
Genes: FMNL3; FHOD3; FRL2; KIAA2014; WBP3
Study 20195266 — Predictive Biomarker (PRD): RNF144A mRNA
Genes: RNF144A; KIAA0161; RNF144; UBCE7IP4
Study 20195266 — Predictive Biomarker (PRD): ASTN2 mRNA
Genes: ASTN2; KIAA0634
Study 20195266 — Predictive Biomarker (PRD): SOX5 mRNA
Genes: SOX5
Study 20195266 — Predictive Biomarker (PRD): ATF7IP2 mRNA
Genes: ATF7IP2; MCAF2
Study 11223322 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24983748 — Predictive Biomarker (PRD): CIDEA mRNA
Genes: CIDEA
Study 22644026 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22644026 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 20394040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20394040 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 20394040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9546928 — Surrogate Endpoint (SUR): Blood pressure
Study 2931840 — Surrogate Endpoint (SUR): Blood pressure
Study 29808753 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 23017527 — Surrogate Endpoint (SUR): Blood pressure
Study 19781896 — Surrogate Endpoint (SUR): Blood pressure
Study 9414432 — Safety Biomarker (SAF): Reactive oxygen species
Study 2065926 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27677865 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 27677865 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 25122497 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17907106 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29788293 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 24598584 — Surrogate Endpoint (SUR): Blood pressure
Study 12597674 — Surrogate Endpoint (SUR): Blood pressure
Study 10334425 — Surrogate Endpoint (SUR): Blood pressure
Study 1721246 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30650480 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 19852290 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11589262 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28045625 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 28045625 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19539184 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15327558 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 28273855 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27411760 — Surrogate Endpoint (SUR): Blood pressure
Study 21884017 — Surrogate Endpoint (SUR): Blood pressure
Study 11738688 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 8296748 — Surrogate Endpoint (SUR): Blood pressure
Study 3046309 — Surrogate Endpoint (SUR): Blood pressure
Study 29136037 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21167685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21167685 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19183414 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 9754723 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 31826326 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 31826326 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 31826326 — Predictive Biomarker (PRD): MMP2 mRNA
Genes: MMP2; CLG4A
Study 31826326 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30611722 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25563737 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 25563737 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25563737 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 25563737 — Surrogate Endpoint (SUR): Plasma ammonia
Study 23926573 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23926573 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22136031 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 22136031 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22136031 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22136031 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21190026 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23892047 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18256870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18256870 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 18256870 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18256870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18256870 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 18256870 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22410021 — Safety Biomarker (SAF): Reactive oxygen species
Study 8918002 — Predictive Biomarker (PRD): TYMP mRNA
Genes: TYMP; ECGF1
Study 29487223 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 20723640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20723640 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20723640 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 31479717 — Predictive Biomarker (PRD): CYP2A6 mRNA
Genes: CYP2A6; CYP2A3
Study 31479717 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31479717 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 31479717 — Predictive Biomarker (PRD): RELA mRNA
Genes: RELA; NFKB3
Study 31479717 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 31479717 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 31479717 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16769916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22047971 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 16842666 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16842666 — Surrogate Endpoint (SUR): Blood pressure
Study 30151798 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 24310818 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 17565935 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18356831 — Surrogate Endpoint (SUR): Blood pressure
Study 17349164 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 17349164 — Surrogate Endpoint (SUR): Blood pressure
Study 9216958 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9216958 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 20386330 — Surrogate Endpoint (SUR): Bacterial count
Study 15494707 — Predictive Biomarker (PRD): PRODH mRNA
Genes: PRODH; PIG6; POX2; PRODH2
Study 9314638 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20691832 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31759938 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9136939 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 18276061 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30554748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28083711 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11