TrialPanorama/TrialPanorama-database huggingface dataset:
Study 1409461 — Surrogate Endpoint (SUR): Blood pressure
Study 1409461 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1409461 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 4010387 — Surrogate Endpoint (SUR): Blood pressure
Study 31298269 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26052866 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31627998 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31627998 — Surrogate Endpoint (SUR): Blood pressure
Study 28808144 — Surrogate Endpoint (SUR): Blood pressure
Study 21571150 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12727970 — Predictive Biomarker (PRD): ALDH1A2 mRNA
Genes: ALDH1A2; RALDH2
Study 12727970 — Predictive Biomarker (PRD): CYP26A1 mRNA
Genes: CYP26A1; CYP26; P450RAI1
Study 12727970 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 11429666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9134634 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 15498183 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15498183 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8131544 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 817373 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 15179339 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8968295 — Surrogate Endpoint (SUR): Blood pressure
Study 15811482 — Surrogate Endpoint (SUR): Blood pressure
Study 11821456 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 11821456 — Predictive Biomarker (PRD): SDC1 mRNA
Genes: SDC1; SDC
Study 8828946 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24037036 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15163108 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 26540369 — Surrogate Endpoint (SUR): Blood pressure
Study 24742658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20496736 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 1449335 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21729789 — Surrogate Endpoint (SUR): Blood pressure
Study 15327583 — Surrogate Endpoint (SUR): Blood pressure
Study 3005384 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3005384 — Surrogate Endpoint (SUR): Blood pressure
Study 16461202 — Surrogate Endpoint (SUR): Blood pressure
Study 7956751 — Predictive Biomarker (PRD): TRIM32 mRNA
Genes: TRIM32; HT2A
Study 2455104 — Surrogate Endpoint (SUR): Blood pressure
Study 7982295 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30640206 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 16968570 — Safety Biomarker (SAF): Interleukin 12
Study 11291826 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 2872805 — Surrogate Endpoint (SUR): Blood pressure
Study 9459535 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2671517 — Surrogate Endpoint (SUR): Bone mineral density
Study 19197823 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 16478902 — Surrogate Endpoint (SUR): Blood pressure
Study 10755315 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8891856 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17931461 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 15826726 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 7710954 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 26444986 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 19695030 — Surrogate Endpoint (SUR): Blood pressure
Study 9627292 — Surrogate Endpoint (SUR): Bone mineral density
Study 27697703 — Predictive Biomarker (PRD): RNASE2 mRNA
Genes: RNASE2; EDN; RNS2
Study 7461567 — Surrogate Endpoint (SUR): Serum uric acid
Study 20391324 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study 18992248 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 14984497 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14984497 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9507791 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 9507791 — Surrogate Endpoint (SUR): Blood pressure
Study 3370986 — Surrogate Endpoint (SUR): Serum potassium
Study 16501249 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16501249 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 16501249 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 14665655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27032570 — Surrogate Endpoint (SUR): Blood pressure
Study 12575551 — Surrogate Endpoint (SUR): Blood pressure
Study 28068681 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28068681 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11316648 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8076711 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 27707817 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 20378841 — Surrogate Endpoint (SUR): Blood pressure
Study 18691293 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 18691293 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study 18691293 — Predictive Biomarker (PRD): CCR4 mRNA
Genes: CCR4; CMKBR4
Study 11273876 — Safety Biomarker (SAF): MTHFR
Study 27776679 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 15703163 — Surrogate Endpoint (SUR): Blood pressure
Study 11174795 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 799559 — Surrogate Endpoint (SUR): Blood pressure
Study 31119578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31119578 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11587253 — Surrogate Endpoint (SUR): Bone mineral density
Study 8162479 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 27916783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19500693 — Monitoring Biomarker (MOI): HBV DNA
Study 11451173 — Monitoring Biomarker (MOI): HBV DNA
Study 31404750 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31404750 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 26302885 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26302885 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26302885 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 26480544 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26480544 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14752676 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 3916444 — Surrogate Endpoint (SUR): Blood pressure
Study 25524052 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23028596 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15000754 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 10073836 — Surrogate Endpoint (SUR): Blood pressure
Study 2071085 — Surrogate Endpoint (SUR): Blood pressure
Study 31504709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25025992 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25025992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21111985 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11674982 — Surrogate Endpoint (SUR): Blood pressure
Study 29035394 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 1356175 — Surrogate Endpoint (SUR): Serum creatinine
Study 3893195 — Surrogate Endpoint (SUR): Blood pressure
Study 26771294 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9685104 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 9685104 — Surrogate Endpoint (SUR): Forced vital capacity
Study 799560 — Surrogate Endpoint (SUR): Blood pressure
Study 23885658 — Predictive Biomarker (PRD): SLPI mRNA
Genes: SLPI; WAP4; WFDC4
Study 23885658 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 23885658 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 16392437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12351451 — Surrogate Endpoint (SUR): Blood pressure
Study 8775856 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2148223 — Surrogate Endpoint (SUR): Blood pressure
Study 23448396 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23448396 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 20965292 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 21577028 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 15361775 — Surrogate Endpoint (SUR): Blood pressure
Study 9313673 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 18480687 — Surrogate Endpoint (SUR): Blood pressure
Study 31232139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31232139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31232139 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31232139 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31232139 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26929396 — Surrogate Endpoint (SUR): Forced vital capacity
Study 18981033 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9295821 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31764785 — Surrogate Endpoint (SUR): Blood pressure
Study 25398453 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25398453 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 25398453 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25398453 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study 25398453 — Safety Biomarker (SAF): Epiregulin
Genes: EREG
Study 21985749 — Surrogate Endpoint (SUR): Blood pressure
Study 18270369 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11164441 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27357093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27357093 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22435370 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22435370 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9389813 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 27302208 — Surrogate Endpoint (SUR): Bone mineral density
Study 27302208 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 22381643 — Surrogate Endpoint (SUR): Blood pressure
Study 19515415 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19515415 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 17475412 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 1692944 — Surrogate Endpoint (SUR): Blood pressure
Study 31471421 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 11524048 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11524048 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15931654 — Surrogate Endpoint (SUR): Serum calcium
Study 12851616 — Surrogate Endpoint (SUR): Serum creatinine
Study 1678372 — Surrogate Endpoint (SUR): Serum calcium
Study 17418297 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16720149 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 1524757 — Surrogate Endpoint (SUR): Blood pressure
Study 26542467 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 23636235 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10948356 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 4014120 — Surrogate Endpoint (SUR): Blood pressure
Study 30921552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30921552 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28858387 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28858387 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20925938 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21635243 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24418359 — Surrogate Endpoint (SUR): Pathological complete response
Study 10895027 — Surrogate Endpoint (SUR): Blood pressure
Study 8826608 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26053726 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26053726 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 17373905 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 17373905 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 17373905 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23804385 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21633800 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study 9576635 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 7889886 — Surrogate Endpoint (SUR): Bone mineral density
Study 16395251 — Safety Biomarker (SAF): Reactive oxygen species
Study 7974894 — Safety Biomarker (SAF): XRCC1
Genes: RCC
Study 24710974 — Predictive Biomarker (PRD): RNPEP mRNA
Genes: RNPEP; APB
Study 16155368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16155368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16155368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9920522 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 26523836 — Predictive Biomarker (PRD): Liver iron
Study 22236402 — Surrogate Endpoint (SUR): Blood pressure
Study 22236402 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15723741 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15723741 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14607208 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1325348 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30985536 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 10100056 — Surrogate Endpoint (SUR): Blood pressure
Study 30850957 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25160859 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 25160859 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21296315 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 24463131 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16086938 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8643415 — Surrogate Endpoint (SUR): Bone mineral density
Study 25377933 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 2210807 — Surrogate Endpoint (SUR): Blood pressure
Study 30678465 — Predictive Biomarker (PRD): ALOX5 mRNA
Genes: ALOX5; LOG5
Study 28520849 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31285738 — Predictive Biomarker (PRD): CD79A mRNA
Genes: CD79A; IGA; MB1
Study 31285738 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28341918 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 28341918 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 15261932 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15261932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15261932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15261932 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 15261932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11600825 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8038980 — Surrogate Endpoint (SUR): Blood pressure
Study 27788579 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study 23996211 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23996211 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 14685005 — Surrogate Endpoint (SUR): Serum creatinine
Study 18172860 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 18172860 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 16980867 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 14610472 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 11302008 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3883972 — Surrogate Endpoint (SUR): Blood pressure
Study 30439313 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17593236 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 2678308 — Surrogate Endpoint (SUR): Blood pressure
Study 25670361 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25670361 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9174299 — Surrogate Endpoint (SUR): Blood pressure
Study 29258938 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 7687708 — Surrogate Endpoint (SUR): Blood pressure
Study 2442513 — Surrogate Endpoint (SUR): Blood pressure
Study 29505101 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 27807925 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16088265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12017349 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11783213 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29330071 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 29330071 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 19058232 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2650582 — Surrogate Endpoint (SUR): Blood pressure
Study 24777970 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17485971 — Surrogate Endpoint (SUR): Blood pressure
Study 2150533 — Surrogate Endpoint (SUR): Blood pressure
Study 28165768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28165768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28165768 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28165768 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 28165768 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8518774 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25556355 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15083754 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31486399 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26818484 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 24325931 — Surrogate Endpoint (SUR): Blood pressure
Study 22121130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22121130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22121130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31092043 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 26567256 — Surrogate Endpoint (SUR): Blood pressure
Study 23652896 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 20175775 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20175775 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 20175775 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 12814453 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8320924 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30541220 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19799592 — Surrogate Endpoint (SUR): Blood pressure
Study 18613992 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11927123 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7604788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein