TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04033965 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study NCT04562740 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03650140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00952159 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT00912392 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00996606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03451383 — Predictive Biomarker (PRD): CCDC88A mRNA
Genes: CCDC88A; APE; GRDN; KIAA1212
Study NCT02702180 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02352753 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04345679 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01106144 — Predictive Biomarker (PRD): XRCC4 mRNA
Genes: XRCC4
Study NCT01106144 — Predictive Biomarker (PRD): LIG4 mRNA
Genes: LIG4
Study NCT01106144 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study NCT01106144 — Predictive Biomarker (PRD): XRCC2 mRNA
Genes: XRCC2
Study NCT01106144 — Predictive Biomarker (PRD): XRCC3 mRNA
Genes: XRCC3
Study NCT01106144 — Predictive Biomarker (PRD): RAD51B mRNA
Genes: RAD51B; RAD51L1; REC2
Study NCT01106144 — Predictive Biomarker (PRD): RAD51C mRNA
Genes: RAD51C; RAD51L2
Study NCT03455270 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03455270 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03874884 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01440816 — Safety Biomarker (SAF): Interleukin 12
Study NCT04084444 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00264771 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT01800877 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01331980 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00609570 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03055312 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04759729 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03386487 — Pharmacodynamic Biomarker (PDY): Fatty acid amide hydrolase 1
Genes: FAAH; FAAH1
Study NCT05033236 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT02764658 — Predictive Biomarker (PRD): PRG4 mRNA
Genes: PRG4; MSF; SZP
Study NCT02600312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02600312 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT02828111 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study NCT02781480 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT02329171 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT02049853 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00501657 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00800995 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT01511068 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04179032 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03942029 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01530581 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01530581 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT02288169 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study NCT04339712 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02238509 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04298957 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00153049 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04642638 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04642638 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01782989 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02633384 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study NCT02633384 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT01678469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00827034 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01023360 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study NCT04887519 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01919801 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00248807 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01762111 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01081847 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT00276809 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04526041 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study NCT03204370 — Predictive Biomarker (PRD): GALNS mRNA
Genes: GALNS
Study NCT00785473 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02387463 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00421499 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03682692 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03682692 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02687139 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01360151 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03225703 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01304537 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT00145574 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04087720 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03776591 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03776591 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00463814 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study NCT03760562 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00004787 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00851461 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00637221 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study NCT04396067 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study NCT04396067 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04396067 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05155566 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT05155566 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05155566 — Predictive Biomarker (PRD): Hormone receptor
Study NCT05155566 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03809403 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT04923360 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study NCT02571088 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02571088 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT03455101 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00790400 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT00672685 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02410239 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03797404 — Predictive Biomarker (PRD): IL3RA mRNA
Genes: IL3RA; IL3R
Study NCT00519181 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT02451462 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04163302 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04163302 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04163302 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study NCT06783738 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00825903 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02477631 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03327740 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT03467035 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT01811693 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02200510 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02048085 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study NCT02569151 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00653809 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT02582294 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT00768365 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00954356 — Predictive Biomarker (PRD): DNA repair endonuclease XPF
Genes: ERCC4; ERCC11; XPF
Study NCT04269057 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT00033514 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04119193 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02606799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03910127 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01972243 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04286659 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT04035369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04035369 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04119232 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01900652 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01372189 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01372189 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03099902 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study NCT04950101 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00380068 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04207190 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT01365494 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01556113 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study NCT02313012 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study NCT02267382 — Predictive Biomarker (PRD): CYP51A1 mRNA
Genes: CYP51A1; CYP51
Study NCT01736540 — Predictive Biomarker (PRD): Liver iron
Study NCT05094960 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00345774 — Predictive Biomarker (PRD): PRX mRNA
Genes: PRX; KIAA1620
Study NCT00069914 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01370655 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03273842 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03838692 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT04071210 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00246701 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03576859 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study NCT00292422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04121637 — Predictive Biomarker (PRD): FNDC5 mRNA
Genes: FNDC5; FRCP2
Study NCT03145922 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03448146 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT02767752 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT04010877 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT01769196 — Predictive Biomarker (PRD): LOXL2 mRNA
Genes: LOXL2
Study NCT01769196 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02010489 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03181776 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01408160 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01408160 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT00974857 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01732770 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01715883 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study NCT01754350 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00354874 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00336986 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study NCT04414982 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02653482 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03230916 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study NCT00610311 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01206582 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT03431753 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study NCT01362062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03223649 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03020342 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03536234 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00444639 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00444639 — Surrogate Endpoint (SUR): Plasma testosterone level
Study NCT04930133 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04930133 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01544868 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02289391 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study NCT02289391 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT04647123 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT04647123 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT05175963 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03814642 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01425242 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00504777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02873039 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00377208 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00655980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02235896 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03039062 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study NCT02597322 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00811681 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT03318497 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study NCT01927315 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT01186055 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT04674189 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02595255 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT02624895 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04212351 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00116805 — Monitoring Biomarker (MOI): HBV DNA
Study NCT03879174 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03879174 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01838915 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03850028 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04084509 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT04084509 — Predictive Biomarker (PRD): PINK1 mRNA
Genes: PINK1
Study NCT00478192 — Surrogate Endpoint (SUR): Serum sodium
Study NCT00500344 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00953615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03468790 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT04471506 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT04471506 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04471506 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT04038164 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT01966952 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04073680 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT04073680 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04073680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT00869232 — Predictive Biomarker (PRD): RAB8A mRNA
Genes: RAB8A; MEL; RAB8
Study NCT03557164 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02719028 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04518540 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00352365 — Predictive Biomarker (PRD): Chromosome 5q
Study NCT03566745 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study NCT00269867 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05770687 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03425149 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03116919 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01895387 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT03727750 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT00311272 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00708344 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02434562 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT02434562 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT00917007 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study NCT01973998 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01973998 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT02672462 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01378442 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03882658 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01178099 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT04189549 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02255084 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03263572 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03263572 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02546297 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT01388114 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT00551200 — Predictive Biomarker (PRD): HPN mRNA
Genes: HPN; TMPRSS1
Study NCT00107536 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00107536 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01263743 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00803647 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04207593 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01540123 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02575092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02575092 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02575092 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03718728 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02054624 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01070511 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT02776436 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04492267 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04524013 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT00951912 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00951912 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01478724 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04093440 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04374695 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04374695 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01439477 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00004050 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00379912 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05570604 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT02397382 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02397382 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT02397382 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT02397382 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02397382 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT02038387 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT05141942 — Surrogate Endpoint (SUR): Serum alkaline phosphatase