TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22587593 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22587593 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22587593 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 22587593 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 6994771 — Surrogate Endpoint (SUR): Blood pressure
Study 12162603 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6465510 — Surrogate Endpoint (SUR): Blood pressure
Study 27672108 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 27672108 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 27672108 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 19880803 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 18945992 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12634581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11314239 — Surrogate Endpoint (SUR): Bone mineral density
Study 8070823 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29280076 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 16444910 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16444910 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12750868 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 10496201 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1676246 — Surrogate Endpoint (SUR): Blood pressure
Study 30015250 — Surrogate Endpoint (SUR): Blood pressure
Study 25160013 — Surrogate Endpoint (SUR): Serum uric acid
Study 31415883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18272933 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1473445 — Surrogate Endpoint (SUR): Blood pressure
Study 31680600 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31680600 — Safety Biomarker (SAF): BDNF
Study 23810881 — Surrogate Endpoint (SUR): Serum potassium
Study 23810881 — Surrogate Endpoint (SUR): Blood pressure
Study 19597054 — Surrogate Endpoint (SUR): Blood pressure
Study 7706609 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31373782 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27699890 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 21766512 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18848434 — Surrogate Endpoint (SUR): Blood pressure
Study 18848434 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18240698 — Surrogate Endpoint (SUR): Blood pressure
Study 18240698 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18240698 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30400876 — Predictive Biomarker (PRD): ABCD2 mRNA
Genes: ABCD2; ALD1; ALDL1; ALDR; ALDRP
Study 18173144 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 18173144 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15711601 — Surrogate Endpoint (SUR): Blood pressure
Study 11801552 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10422932 — Surrogate Endpoint (SUR): Blood pressure
Study 11300425 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8322777 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8322777 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18422590 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 18422590 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 18422590 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 18422590 — Surrogate Endpoint (SUR): Bone mineral density
Study 14976882 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 14976882 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14976882 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 14976882 — Safety Biomarker (SAF): Hyaluronic acid
Study 3609849 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 30701878 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8501142 — Surrogate Endpoint (SUR): Bone mineral density
Study 3687038 — Surrogate Endpoint (SUR): Blood pressure
Study 23077042 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 15746650 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15746650 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15746650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23720950 — Surrogate Endpoint (SUR): Blood pressure
Study 21890226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21890226 — Surrogate Endpoint (SUR): Blood pressure
Study 21890226 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2523660 — Surrogate Endpoint (SUR): Blood pressure
Study 2523660 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 848803 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 21252704 — Surrogate Endpoint (SUR): Serum creatinine
Study 11049104 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 9350846 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 29406835 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study 23613810 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 23613810 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 31373648 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27666380 — Surrogate Endpoint (SUR): Blood pressure
Study 23532097 — Surrogate Endpoint (SUR): Serum creatinine
Study 18227766 — Safety Biomarker (SAF): Hyaluronic acid
Study 16595356 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26085515 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 9207618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9207618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21700944 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8639796 — Predictive Biomarker (PRD): CLEC4D mRNA
Genes: CLEC4D; CLECSF8; MCL
Study 27650051 — Surrogate Endpoint (SUR): Blood pressure
Study 18347544 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 10652047 — Surrogate Endpoint (SUR): Bone mineral density
Study 10652047 — Surrogate Endpoint (SUR): Serum creatinine
Study 24667140 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28489775 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 21565138 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15117407 — Predictive Biomarker (PRD): FGF4 mRNA
Genes: FGF4; HST; HSTF1; KS3
Study 9241103 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22079391 — Surrogate Endpoint (SUR): Serum uric acid
Study 18386567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18386567 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15723737 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15723737 — Safety Biomarker (SAF): Reactive oxygen species
Study 8340155 — Surrogate Endpoint (SUR): Blood pressure
Study 3032537 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28033130 — Surrogate Endpoint (SUR): Blood pressure
Study 23819344 — Surrogate Endpoint (SUR): Serum creatinine
Study 25596179 — Monitoring Biomarker (MOI): HBV DNA
Study 24449105 — Surrogate Endpoint (SUR): Blood pressure
Study 15043687 — Surrogate Endpoint (SUR): Blood pressure
Study 25780062 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23304686 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 23304686 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17341565 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 15761754 — Safety Biomarker (SAF): 51Cr-EDTA
Study 15761754 — Surrogate Endpoint (SUR): Blood pressure
Study 10207208 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 2140961 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2140961 — Surrogate Endpoint (SUR): Blood pressure
Study 23894865 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 21646599 — Surrogate Endpoint (SUR): Blood pressure
Study 16410677 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 28830428 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28830428 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 9223734 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9223734 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 3072419 — Surrogate Endpoint (SUR): Blood pressure
Study 3072419 — Surrogate Endpoint (SUR): Serum potassium
Study 3072419 — Surrogate Endpoint (SUR): Serum creatinine
Study 30324975 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2285641 — Surrogate Endpoint (SUR): Blood pressure
Study 29146139 — Surrogate Endpoint (SUR): Serum creatinine
Study 17704027 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12602532 — Surrogate Endpoint (SUR): Blood pressure
Study 12602532 — Surrogate Endpoint (SUR): Serum calcium
Study 22966894 — Surrogate Endpoint (SUR): Blood pressure
Study 16195478 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 16195478 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24806033 — Surrogate Endpoint (SUR): Serum creatinine
Study 23257888 — Surrogate Endpoint (SUR): Blood pressure
Study 21329495 — Surrogate Endpoint (SUR): Blood pressure
Study 19253124 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 6310241 — Surrogate Endpoint (SUR): Serum creatinine
Study 6310241 — Surrogate Endpoint (SUR): Serum calcium
Study 20135645 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16046714 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 11783152 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26689707 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 16139403 — Surrogate Endpoint (SUR): Bone mineral density
Study 3061400 — Surrogate Endpoint (SUR): Blood pressure
Study 29709643 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 29709643 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28933961 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 28933961 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28933961 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 28933961 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 19956091 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 11320369 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11320369 — Surrogate Endpoint (SUR): Blood pressure
Study 10322821 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8494577 — Surrogate Endpoint (SUR): Blood pressure
Study 8494577 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 25829142 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20005355 — Surrogate Endpoint (SUR): Serum creatinine
Study 22329591 — Surrogate Endpoint (SUR): Blood pressure
Study 7760888 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7760888 — Surrogate Endpoint (SUR): Blood pressure
Study 85937 — Surrogate Endpoint (SUR): Blood pressure
Study 21851461 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 21851461 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21851461 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17239888 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17239888 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27161750 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8606813 — Surrogate Endpoint (SUR): Serum potassium
Study 8606813 — Surrogate Endpoint (SUR): Blood pressure
Study 26899019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 26899019 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 22608107 — Surrogate Endpoint (SUR): Blood pressure
Study 20573633 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 6191948 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 25376639 — Surrogate Endpoint (SUR): Blood pressure
Study 11597376 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30012391 — Surrogate Endpoint (SUR): Blood pressure
Study 27618090 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27618090 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25172950 — Predictive Biomarker (PRD): CACNA1C mRNA
Genes: CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1
Study 10319076 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8732324 — Surrogate Endpoint (SUR): Blood pressure
Study 8517385 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8517385 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26860807 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 25130788 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25130788 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25130788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25130788 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25130788 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 19342701 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 23477205 — Surrogate Endpoint (SUR): Bone mineral density
Study 20942666 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2164204 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17565634 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19237249 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 26486702 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26486702 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 24199974 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24199974 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8557971 — Surrogate Endpoint (SUR): Blood pressure
Study 8657524 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 1632391 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31375452 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27236883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15861352 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15861352 — Surrogate Endpoint (SUR): Blood pressure
Study 15861352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10196731 — Surrogate Endpoint (SUR): Blood pressure
Study 31513088 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21297287 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1531952 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26987589 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16146472 — Surrogate Endpoint (SUR): Blood pressure
Study 11246561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11246561 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 11246561 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 9566100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7827399 — Surrogate Endpoint (SUR): Serum calcium
Study 12540551 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28514347 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 25560575 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25560575 — Predictive Biomarker (PRD): DEF6 mRNA
Genes: DEF6; IBP
Study 25560575 — Surrogate Endpoint (SUR): Blood pressure
Study 23621161 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 6356628 — Surrogate Endpoint (SUR): Blood pressure
Study 25697725 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 21434341 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 21434341 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 21434341 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21434341 — Safety Biomarker (SAF): IL-6 and IL-10
Study 9094151 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3510088 — Surrogate Endpoint (SUR): Blood pressure
Study 30054920 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30054920 — Surrogate Endpoint (SUR): Serum creatinine
Study 30054920 — Surrogate Endpoint (SUR): Blood pressure
Study 25223724 — Surrogate Endpoint (SUR): Blood pressure
Study 27804174 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 7391628 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 26721134 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26721134 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22405557 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16311300 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 16311300 — Predictive Biomarker (PRD): CASP3 mRNA
Genes: CASP3; CPP32
Study 16311300 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 16311300 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22535748 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 20685495 — Surrogate Endpoint (SUR): Blood pressure
Study 16503317 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16503317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16503317 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12094185 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31483891 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 21226820 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 21226820 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23337366 — Surrogate Endpoint (SUR): Bone mineral density
Study 20088416 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20088416 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7634504 — Surrogate Endpoint (SUR): Bone mineral density
Study 26343717 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26343717 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23835687 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 10229297 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 3892794 — Surrogate Endpoint (SUR): Serum creatinine
Study 12888137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2060557 — Surrogate Endpoint (SUR): Blood pressure
Study 19816415 — Surrogate Endpoint (SUR): Blood pressure
Study 10770345 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8914032 — Surrogate Endpoint (SUR): Serum creatinine
Study 8914032 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27788949 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 17272375 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31821506 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27102504 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17030687 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12747268 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12747268 — Surrogate Endpoint (SUR): Bone mineral density
Study 8166061 — Surrogate Endpoint (SUR): Blood pressure
Study 31792945 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 28400411 — Predictive Biomarker (PRD): FAU mRNA
Genes: FAU
Study 23519371 — Surrogate Endpoint (SUR): Blood pressure
Study 15289018 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 30659035 — Predictive Biomarker (PRD): ZDHHC2 mRNA
Genes: ZDHHC2; REAM; REC; ZNF372
Study 30101851 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30101851 — Surrogate Endpoint (SUR): Serum uric acid
Study 25316503 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 2654171 — Surrogate Endpoint (SUR): Serum testosterone
Study 9431839 — Surrogate Endpoint (SUR): Blood pressure
Study 31174535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31174535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28834553 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 23343686 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 14713761 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 14713761 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14713761 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18955670 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 12795786 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10969261 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2