TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26803754 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 26806010 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26808671 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26810133 — Predictive Biomarker (PRD): ABCC3 mRNA
Genes: ABCC3; CMOAT2; MLP2; MRP3
Study 26811129 — Surrogate Endpoint (SUR): Blood pressure
Study 26812968 — Surrogate Endpoint (SUR): Blood pressure
Study 26813675 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 26813675 — Predictive Biomarker (PRD): CD200 mRNA
Genes: CD200; MOX1; MOX2; My033
Study 26813675 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 26817280 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26818566 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26819054 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26819054 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 26819054 — Predictive Biomarker (PRD): CSF1R mRNA
Genes: CSF1R; FMS
Study 26819296 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 26819748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26819752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26822149 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 26822149 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 26822279 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26822963 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 26823971 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 26825170 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26826134 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26826513 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 26828531 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 26829377 — Predictive Biomarker (PRD): PPP1R15A mRNA
Genes: PPP1R15A; GADD34
Study 26829441 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26829444 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26830967 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study 26830967 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 26831232 — Monitoring Biomarker (MOI): HBV DNA
Study 26832194 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26832367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26834058 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26835225 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26835225 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26835906 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 26836193 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 26836193 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 26839475 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26839476 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26842272 — Surrogate Endpoint (SUR): Blood pressure
Study 26843560 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 26844283 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26844283 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 26845282 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26849144 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 26850626 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26852658 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 26852658 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 26853180 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26853249 — Predictive Biomarker (PRD): SLC25A3 mRNA
Genes: SLC25A3; PHC; OK/SW-cl.48
Study 26853647 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 26853647 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26853647 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 26853647 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 26857702 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26858124 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 26859103 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 26859103 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26859761 — Predictive Biomarker (PRD): FCER2 mRNA
Genes: FCER2; CD23A; CLEC4J; FCE2; IGEBF
Study 26859761 — Predictive Biomarker (PRD): LY86 mRNA
Genes: LY86; MD1
Study 26861458 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26861602 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26861602 — Predictive Biomarker (PRD): Hormone receptor
Study 26861905 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 26863635 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26864794 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26864794 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26865277 — Predictive Biomarker (PRD): IQGAP2 mRNA
Genes: IQGAP2
Study 26865277 — Predictive Biomarker (PRD): KLF4 mRNA
Genes: KLF4; EZF; GKLF
Study 26865594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26865594 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26865594 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 26867061 — Surrogate Endpoint (SUR): Blood pressure
Study 26868433 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 26868433 — Predictive Biomarker (PRD): ENPP1 mRNA
Genes: ENPP1; M6S1; NPPS; PC1; PDNP1
Study 26868433 — Predictive Biomarker (PRD): TRIB3 mRNA
Genes: TRIB3; C20orf97; NIPK; SKIP3; TRB3
Study 26869376 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26869631 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 26870387 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 26870801 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 26871197 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 26871197 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 26871769 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 26872154 — Predictive Biomarker (PRD): PKP3 mRNA
Genes: PKP3
Study 26872154 — Predictive Biomarker (PRD): SIGIRR mRNA
Genes: SIGIRR; UNQ301/PRO342
Study 26872154 — Predictive Biomarker (PRD): ANO9 mRNA
Genes: ANO9; PIG5; TMEM16J; TP53I5
Study 26872154 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 26872154 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 26873642 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 26873642 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study 26873693 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26873693 — Surrogate Endpoint (SUR): Blood pressure
Study 26874378 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26874395 — Surrogate Endpoint (SUR): Blood pressure
Study 26876245 — Surrogate Endpoint (SUR): Serum creatinine
Study 26879849 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 26879979 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26880104 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 26880104 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26880668 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26882402 — Predictive Biomarker (PRD): MUC2 mRNA
Genes: MUC2; SMUC
Study 26882402 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 26882402 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study 26882907 — Surrogate Endpoint (SUR): Pathological complete response
Study 26883583 — Predictive Biomarker (PRD): EZH2 mRNA
Genes: EZH2; KMT6
Study 26883583 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study 26883583 — Monitoring Biomarker (MOI): Cell-free DNA
Study 26884591 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 26884591 — Predictive Biomarker (PRD): NTRK3 mRNA
Genes: NTRK3; TRKC
Study 26884591 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study 26888382 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26888535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26888535 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26888975 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26888975 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26889973 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26891037 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26892510 — Surrogate Endpoint (SUR): Blood pressure
Study 26892510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26893500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26895792 — Surrogate Endpoint (SUR): Blood pressure
Study 26897675 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 26898568 — Safety Biomarker (SAF): UGT1A1
Genes: UGT1A
Study 26898607 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26899665 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study 26902643 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 26902643 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26902761 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26902828 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26903311 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study 26903799 — Predictive Biomarker (PRD): VIM mRNA
Genes: VIM
Study 26903799 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 26903799 — Surrogate Endpoint (SUR): Blood pressure
Study 26904207 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 26904404 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 26907630 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 26908786 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26911310 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26911408 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26911408 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 26911408 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26911477 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26911519 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26911583 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26912134 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 26912492 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26915009 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26915709 — Surrogate Endpoint (SUR): Blood pressure
Study 26916582 — Surrogate Endpoint (SUR): Blood pressure
Study 26917438 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26917615 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 26918032 — Surrogate Endpoint (SUR): Blood pressure
Study 26919403 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 26919403 — Predictive Biomarker (PRD): PCA3
Study 26920728 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 26921148 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26924680 — Predictive Biomarker (PRD): DDC mRNA
Genes: DDC; AADC
Study 26925252 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26926297 — Safety Biomarker (SAF): Hyaluronic acid
Study 26926676 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 26926676 — Predictive Biomarker (PRD): Hormone receptor
Study 26926676 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 26926676 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26927285 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 26927285 — Predictive Biomarker (PRD): ABCC4 mRNA
Genes: ABCC4; MOATB; MRP4
Study 26928328 — Predictive Biomarker (PRD): TLR8 mRNA
Genes: TLR8; UNQ249/PRO286
Study 26928328 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study 26928328 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 26928328 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26930208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26930208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26930208 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 26930208 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 26930208 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 26930627 — Surrogate Endpoint (SUR): Serum creatinine
Study 26931143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26931143 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26933421 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26933507 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 26933507 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 26934750 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 26937680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26937680 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 26937680 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 26940214 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 26940214 — Surrogate Endpoint (SUR): Blood pressure
Study 26941415 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26942886 — Predictive Biomarker (PRD): Tubulin beta-3 chain
Genes: TUBB3; TUBB4
Study 26942886 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 26942886 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 26942886 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study 26944198 — Predictive Biomarker (PRD): ZFYVE16 mRNA
Genes: ZFYVE16; KIAA0305
Study 26945673 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 26945673 — Predictive Biomarker (PRD): AVPR1A mRNA
Genes: AVPR1A; AVPR1
Study 26945673 — Predictive Biomarker (PRD): GCH1 mRNA
Genes: GCH1; DYT5; GCH
Study 26945673 — Predictive Biomarker (PRD): KCNS1 mRNA
Genes: KCNS1
Study 26945673 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 26945673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26945673 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26945843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26946290 — Predictive Biomarker (PRD): HMGCR mRNA
Genes: HMGCR
Study 26946290 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 26946290 — Predictive Biomarker (PRD): APOB mRNA
Genes: APOB
Study 26946290 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 26946290 — Predictive Biomarker (PRD): NPC1L1 mRNA
Genes: NPC1L1
Study 26948580 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 26948683 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26951396 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 26951635 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26951635 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 26951820 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26951820 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 26951967 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26952546 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26958364 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26960790 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 26961146 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 26961932 — Surrogate Endpoint (SUR): Blood pressure
Study 26962183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26962183 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26962183 — Predictive Biomarker (PRD): ADGRE1 mRNA
Genes: ADGRE1; EMR1; TM7LN3
Study 26962183 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 26962189 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 26966027 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 26966029 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 26967692 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 26968708 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26970832 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26970832 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26971488 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 26971680 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 26972567 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26972567 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26973142 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26973324 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 26973538 — Predictive Biomarker (PRD): DSPP mRNA
Genes: DSPP
Study 26974332 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26974430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26974430 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 26974430 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26974526 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 26975189 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26980207 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 26980473 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26981247 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26981247 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26982511 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 26983912 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 26983912 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 26984361 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 26984445 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26984642 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2