TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20921430 — Surrogate Endpoint (SUR): Blood pressure
Study 15854167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12878616 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10235439 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 10235439 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8909067 — Surrogate Endpoint (SUR): Blood pressure
Study 30160043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22318996 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22318996 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27430941 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27430941 — Surrogate Endpoint (SUR): Blood pressure
Study 18778469 — Surrogate Endpoint (SUR): Blood pressure
Study 16171525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16171525 — Surrogate Endpoint (SUR): Bone mineral density
Study 19623188 — Surrogate Endpoint (SUR): Blood pressure
Study 1387500 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1387500 — Surrogate Endpoint (SUR): Blood pressure
Study 29613826 — Predictive Biomarker (PRD): HBEGF mRNA
Genes: HBEGF; DTR; DTS; HEGFL
Study 24485487 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22894958 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17662087 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 17662087 — Surrogate Endpoint (SUR): Serum creatinine
Study 15761089 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23640485 — Safety Biomarker (SAF): Reactive oxygen species
Study 23640485 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15234287 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11576883 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 11576883 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11576883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11576883 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11576883 — Surrogate Endpoint (SUR): Serum calcium
Study 31654593 — Surrogate Endpoint (SUR): Serum creatinine
Study 26100988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19347770 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 10550466 — Surrogate Endpoint (SUR): Bone mineral density
Study 2081141 — Surrogate Endpoint (SUR): Blood pressure
Study 22613545 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 22613545 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 22613545 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17274711 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 22996743 — Surrogate Endpoint (SUR): Bone mineral density
Study 22192583 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14674905 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 28131423 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27318344 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 27318344 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12527544 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 28185274 — Safety Biomarker (SAF): Reactive oxygen species
Study 24496201 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 18356552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 18356552 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17162709 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10445623 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2347116 — Surrogate Endpoint (SUR): Blood pressure
Study 2347116 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31980448 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15794385 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 12425728 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12425728 — Surrogate Endpoint (SUR): Plasma sitosterol and campesterol
Study 9928724 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24590773 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study 19886838 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28926855 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26805750 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 8354735 — Surrogate Endpoint (SUR): Blood pressure
Study 26909786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26909786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26909786 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21055963 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 12627041 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 30427246 — Surrogate Endpoint (SUR): Blood pressure
Study 25499536 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 23466709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19685113 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 11376827 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11376827 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 23216900 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 21249489 — Predictive Biomarker (PRD): VPS13C mRNA
Genes: VPS13C; KIAA1421
Study 21249489 — Predictive Biomarker (PRD): C2CD4A mRNA
Genes: C2CD4A; FAM148A; NLF1
Study 21249489 — Predictive Biomarker (PRD): C2CD4B mRNA
Genes: C2CD4B; FAM148B; NLF2
Study 8959423 — Surrogate Endpoint (SUR): Blood pressure
Study 1525903 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 30244288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30244288 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 15752881 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2404052 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23559402 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 23559402 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 23559402 — Predictive Biomarker (PRD): GSTM3 mRNA
Genes: GSTM3; GST5
Study 23559402 — Predictive Biomarker (PRD): GRIN2B mRNA
Genes: GRIN2B; NMDAR2B
Study 23559402 — Predictive Biomarker (PRD): HTR2A mRNA
Genes: HTR2A; HTR2
Study 23559402 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23559402 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 23559402 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 29703289 — Safety Biomarker (SAF): Hyaluronic acid
Study 11920355 — Surrogate Endpoint (SUR): Serum sodium
Study 20536946 — Surrogate Endpoint (SUR): Blood pressure
Study 7675936 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7675936 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 23975474 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19535242 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28640168 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 21295742 — Surrogate Endpoint (SUR): Bone mineral density
Study 15278681 — Safety Biomarker (SAF): Interleukin 1
Study 15278681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15278681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10030393 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 26471236 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 15068719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15068719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17346524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9756115 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 7848600 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7848600 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8573993 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 791564 — Surrogate Endpoint (SUR): Blood pressure
Study 30734702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20460257 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 14621036 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31599200 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 24511017 — Predictive Biomarker (PRD): YAP1 mRNA
Genes: YAP1; YAP65
Study 22219013 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 16283062 — Surrogate Endpoint (SUR): Bone mineral density
Study 6352951 — Surrogate Endpoint (SUR): Blood pressure
Study 26946735 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9294113 — Surrogate Endpoint (SUR): Bone mineral density
Study 24496312 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 3285485 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 3285485 — Surrogate Endpoint (SUR): Serum testosterone
Study 31257177 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31257177 — Predictive Biomarker (PRD): Hormone receptor
Study 22980307 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22980307 — Surrogate Endpoint (SUR): Blood pressure
Study 20195181 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9935020 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29195602 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 24381278 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 17449580 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17449580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8814495 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19332493 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 14711459 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29294154 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 14760090 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 9923580 — Surrogate Endpoint (SUR): Blood pressure
Study 8087824 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30508863 — Predictive Biomarker (PRD): KIR2DS4 mRNA
Genes: KIR2DS4; CD158I; KKA3; NKAT8
Study 30508863 — Predictive Biomarker (PRD): KIR3DL1 mRNA
Genes: KIR3DL1; CD158E; NKAT3; NKB1
Study 28202885 — Surrogate Endpoint (SUR): Serum creatinine
Study 17900783 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 15120509 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 15120509 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15120509 — Safety Biomarker (SAF): Reactive oxygen species
Study 15120509 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10204813 — Surrogate Endpoint (SUR): Blood pressure
Study 25881079 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 25881079 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21435103 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 14762367 — Surrogate Endpoint (SUR): Blood pressure
Study 15464318 — Surrogate Endpoint (SUR): Serum creatinine
Study 9849693 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9849693 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7889637 — Surrogate Endpoint (SUR): Serum calcium
Study 26625194 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 17115389 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15518603 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 31216210 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 21536090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19499294 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 3535012 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3535012 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 26046585 — Surrogate Endpoint (SUR): Blood pressure
Study 25013997 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18474811 — Safety Biomarker (SAF): Interleukin 1
Study 18474811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18474811 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18474811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8869862 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 19864243 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16979857 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11682380 — Surrogate Endpoint (SUR): Blood pressure
Study 2835195 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2835195 — Surrogate Endpoint (SUR): Blood pressure
Study 26245216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30791871 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28236978 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 28236978 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 23089999 — Surrogate Endpoint (SUR): Blood pressure
Study 8523053 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26510851 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 19218306 — Predictive Biomarker (PRD): Hormone receptor
Study 19218306 — Surrogate Endpoint (SUR): Bone mineral density
Study 7851592 — Surrogate Endpoint (SUR): Sperm parameters
Study 31711752 — Monitoring Biomarker (MOI): HBV DNA
Study 23303903 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 7742745 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 30707360 — Predictive Biomarker (PRD): HRC mRNA
Genes: HRC; HCP
Study 24644139 — Surrogate Endpoint (SUR): Blood pressure
Study 17942381 — Surrogate Endpoint (SUR): Bone mineral density
Study 31740722 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 28471973 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 23264555 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 19943976 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 9393270 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24730354 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22502790 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22502790 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12846760 — Surrogate Endpoint (SUR): Blood pressure
Study 22752379 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 15167592 — Surrogate Endpoint (SUR): Serum calcium
Study 15167592 — Surrogate Endpoint (SUR): Bone mineral density
Study 11411734 — Surrogate Endpoint (SUR): Blood pressure
Study 24460649 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 19531226 — Surrogate Endpoint (SUR): Blood pressure
Study 7635580 — Surrogate Endpoint (SUR): Blood pressure
Study 9801975 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 30786861 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 28005705 — Surrogate Endpoint (SUR): Blood pressure
Study 23237479 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 16342231 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 16342231 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 14597948 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 10227336 — Surrogate Endpoint (SUR): Serum potassium
Study 10227336 — Surrogate Endpoint (SUR): Blood pressure
Study 9156929 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 1914371 — Surrogate Endpoint (SUR): Blood pressure
Study 29797914 — Surrogate Endpoint (SUR): Bone mineral density
Study 26151336 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 16546473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12712350 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10856736 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8674324 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29136227 — Surrogate Endpoint (SUR): Blood pressure
Study 23727146 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23727146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23727146 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23727146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23727146 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23155956 — Surrogate Endpoint (SUR): Blood pressure
Study 18833819 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 10733041 — Surrogate Endpoint (SUR): Blood pressure
Study 8866628 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 6093182 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31283957 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26603744 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22185496 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 22185496 — Surrogate Endpoint (SUR): Blood pressure
Study 24401239 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 24401239 — Safety Biomarker (SAF): Reactive oxygen species
Study 19730107 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 1798280 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24385328 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22742885 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 20460548 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28255756 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 25746670 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23917585 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21712241 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 21712241 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16682305 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 2509267 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25910473 — Predictive Biomarker (PRD): NXN mRNA
Genes: NXN; NRX
Study 18344556 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17162891 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 8777274 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8777274 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 8777274 — Safety Biomarker (SAF): Interleukin 1
Study 30528951 — Surrogate Endpoint (SUR): Blood pressure
Study 15361773 — Surrogate Endpoint (SUR): Blood pressure
Study 9863121 — Predictive Biomarker (PRD): RTEL1 mRNA
Genes: RTEL1; C20orf41; KIAA1088; NHL
Study 24045440 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 20949292 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 10051728 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28892233 — Safety Biomarker (SAF): Hyaluronic acid
Study 21747052 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 19269895 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 16817177 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 25856225 — Surrogate Endpoint (SUR): Bone mineral density
Study 15796091 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26141306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22776860 — Surrogate Endpoint (SUR): Bone mineral density
Study 31919319 — Predictive Biomarker (PRD): HCG22 mRNA
Genes: HCG22; G2; PBMUCL2
Study 20682687 — Safety Biomarker (SAF): MATE1
Genes: SLC47A1; FLJ10847
Study 20682687 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 20682687 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 20682687 — Predictive Biomarker (PRD): PRKAA1 mRNA
Genes: PRKAA1; AMPK1
Study 20682687 — Predictive Biomarker (PRD): PRKAA2 mRNA
Genes: PRKAA2; AMPK; AMPK2
Study 20682687 — Predictive Biomarker (PRD): SLC22A1 mRNA
Genes: SLC22A1; OCT1
Study 20682687 — Predictive Biomarker (PRD): PRKAG2 mRNA
Genes: PRKAG2
Study 17335299 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study 16034448 — Surrogate Endpoint (SUR): Blood pressure