TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7836219 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7836219 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28298397 — Surrogate Endpoint (SUR): Blood pressure
Study 18635268 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31183921 — Surrogate Endpoint (SUR): Blood pressure
Study 31183921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25249300 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17305268 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 3554084 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 24812901 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24812901 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 31638594 — Predictive Biomarker (PRD): TKTL1 mRNA
Genes: TKTL1; TKR; TKT2
Study 20212264 — Surrogate Endpoint (SUR): Blood pressure
Study 20212264 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27342501 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 19174783 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 29154060 — Safety Biomarker (SAF): RYR1
Genes: RYR; PPP1R137
Study 29154060 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23077975 — Surrogate Endpoint (SUR): Blood pressure
Study 31390641 — Surrogate Endpoint (SUR): Blood pressure
Study 30043039 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18313127 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3009292 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20102356 — Surrogate Endpoint (SUR): Serum sodium
Study 17262795 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 17663101 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28011099 — Surrogate Endpoint (SUR): Blood pressure
Study 27100753 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25715047 — Surrogate Endpoint (SUR): Blood pressure
Study 11834948 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2287048 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30927252 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23867729 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 21458815 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21458815 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16817048 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 11708608 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 30289105 — Surrogate Endpoint (SUR): Blood pressure
Study 19952843 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 16846409 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12848279 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10726893 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 363254 — Predictive Biomarker (PRD): BANF1 mRNA
Genes: BANF1; BAF; BCRG1
Study 25694383 — Surrogate Endpoint (SUR): Bone mineral density
Study 12885707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2017011 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7318344 — Surrogate Endpoint (SUR): Blood pressure
Study 31318879 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27933348 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 23713736 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 21107432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21107432 — Surrogate Endpoint (SUR): Blood pressure
Study 21107432 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21107432 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 15209480 — Surrogate Endpoint (SUR): Blood pressure
Study 26104969 — Surrogate Endpoint (SUR): Blood pressure
Study 10216796 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10216796 — Surrogate Endpoint (SUR): Blood pressure
Study 20446828 — Surrogate Endpoint (SUR): Bone mineral density
Study 29255190 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 22215654 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 16274036 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9466469 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 9466469 — Safety Biomarker (SAF): Cytochrome c
Study 7623370 — Surrogate Endpoint (SUR): Blood pressure
Study 28668204 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8740511 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8740511 — Surrogate Endpoint (SUR): Blood pressure
Study 31922425 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26840067 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20664618 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 12020184 — Surrogate Endpoint (SUR): Bone mineral density
Study 1536410 — Surrogate Endpoint (SUR): Serum potassium
Study 29254987 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27373605 — Surrogate Endpoint (SUR): Blood pressure
Study 25287144 — Surrogate Endpoint (SUR): Blood pressure
Study 21659904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16075782 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 8357360 — Surrogate Endpoint (SUR): Blood pressure
Study 8357360 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29455212 — Predictive Biomarker (PRD): CGN mRNA
Genes: CGN; KIAA1319
Study 29455212 — Surrogate Endpoint (SUR): Blood pressure
Study 27221567 — Surrogate Endpoint (SUR): Blood pressure
Study 24366937 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24366937 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 29383896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29383896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29383896 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27798895 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 25023200 — Surrogate Endpoint (SUR): Serum creatinine
Study 20497432 — Surrogate Endpoint (SUR): Blood pressure
Study 8651227 — Surrogate Endpoint (SUR): Blood pressure
Study 18356109 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11192323 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11192323 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8791185 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 24983262 — Surrogate Endpoint (SUR): Blood pressure
Study 22876442 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22876442 — Surrogate Endpoint (SUR): Blood pressure
Study 22876442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15860240 — Surrogate Endpoint (SUR): Blood pressure
Study 12537209 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 12537209 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8656502 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1658975 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1658975 — Surrogate Endpoint (SUR): Blood pressure
Study 11897208 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11897208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8548055 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 2122514 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 30721997 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30721997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30721997 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9542607 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28882371 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23873559 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 11767316 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3793280 — Surrogate Endpoint (SUR): Blood pressure
Study 25141250 — Surrogate Endpoint (SUR): Blood pressure
Study 15982504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15982504 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1414927 — Surrogate Endpoint (SUR): Blood pressure
Study 30207844 — Predictive Biomarker (PRD): CDON mRNA
Genes: CDON; CDO
Study 26374194 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 26194374 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26194374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26194374 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26194374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19248698 — Surrogate Endpoint (SUR): Blood pressure
Study 25218597 — Predictive Biomarker (PRD): MNT mRNA
Genes: MNT; BHLHD3; ROX
Study 25218597 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20177797 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 10096928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10096928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22792813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6329547 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28552878 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 24330691 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 28857461 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26948252 — Surrogate Endpoint (SUR): Serum creatinine
Study 26948252 — Surrogate Endpoint (SUR): Serum sodium
Study 22357522 — Surrogate Endpoint (SUR): Blood pressure
Study 10594483 — Predictive Biomarker (PRD): BANF1 mRNA
Genes: BANF1; BAF; BCRG1
Study 10594483 — Predictive Biomarker (PRD): BLVRA mRNA
Genes: BLVRA; BLVR; BVR
Study 8546738 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1986287 — Surrogate Endpoint (SUR): Blood pressure
Study 10442852 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 30916575 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 30916575 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 30916575 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 28551058 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 7816261 — Surrogate Endpoint (SUR): Serum creatinine
Study 31845487 — Predictive Biomarker (PRD): TTN mRNA
Genes: TTN
Study 26924265 — Surrogate Endpoint (SUR): Bone mineral density
Study 23073171 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 21626077 — Surrogate Endpoint (SUR): Blood pressure
Study 16634837 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 16634837 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 16634837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16634837 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14519707 — Surrogate Endpoint (SUR): Bone mineral density
Study 10534147 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1871692 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22748458 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 18195164 — Surrogate Endpoint (SUR): Blood pressure
Study 1734572 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20978259 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20978259 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 18482101 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 31829910 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19191674 — Surrogate Endpoint (SUR): Blood pressure
Study 17121197 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 17121197 — Predictive Biomarker (PRD): PLXNB1 mRNA
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 11744584 — Surrogate Endpoint (SUR): Blood pressure
Study 3511689 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3511689 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23517509 — Surrogate Endpoint (SUR): Bone mineral density
Study 2885298 — Surrogate Endpoint (SUR): Blood pressure
Study 31925811 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 18825157 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18825157 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18825157 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12678140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10781759 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10781759 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24549105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23259270 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 18507721 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2781119 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 28882919 — Surrogate Endpoint (SUR): Blood pressure
Study 23578552 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23578552 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 23578552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14626567 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20133508 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16435076 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 16435076 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 16435076 — Surrogate Endpoint (SUR): Bone mineral density
Study 6367406 — Surrogate Endpoint (SUR): Blood pressure
Study 12006904 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 2225715 — Surrogate Endpoint (SUR): Blood pressure
Study 25967707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25967707 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24037015 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15089807 — Surrogate Endpoint (SUR): Blood pressure
Study 19837094 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19837094 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 27862950 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27862950 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ESR2 mRNA
Genes: ESR2; ESTRB; NR3A2
Study 27862950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16636528 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8429800 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 8429800 — Surrogate Endpoint (SUR): Blood pressure
Study 27742464 — Surrogate Endpoint (SUR): Blood pressure
Study 12538037 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12538037 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12538037 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12538037 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12538037 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26844926 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 26844926 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 28790113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): NTSR1 mRNA
Genes: NTSR1; NTRR
Study 28790113 — Predictive Biomarker (PRD): NTS mRNA
Genes: NTS
Study 3338249 — Predictive Biomarker (PRD): CPA6 mRNA
Genes: CPA6; CPAH
Study 23523641 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16820579 — Predictive Biomarker (PRD): ADRB1 mRNA
Genes: ADRB1; ADRB1R; B1AR
Study 16820579 — Predictive Biomarker (PRD): PLB1 mRNA
Genes: PLB1; PLB
Study 1975196 — Surrogate Endpoint (SUR): Blood pressure
Study 10098223 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1911582 — Surrogate Endpoint (SUR): Blood pressure
Study 7126388 — Surrogate Endpoint (SUR): Blood pressure
Study 30883766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30883766 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28273285 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 21737486 — Surrogate Endpoint (SUR): Blood pressure
Study 2992562 — Surrogate Endpoint (SUR): Blood pressure
Study 25377592 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30448246 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 19178404 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 23803334 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 8801192 — Safety Biomarker (SAF): Reactive oxygen species
Study 1377455 — Surrogate Endpoint (SUR): Blood pressure
Study 30235384 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 12198065 — Surrogate Endpoint (SUR): Blood pressure
Study 29421065 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 22936334 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22936334 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 22936334 — Safety Biomarker (SAF): BDNF
Study 22936334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22936334 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23146280 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23146280 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23146280 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 23146280 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23146280 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20703222 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study 17387131 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17387131 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17387131 — Surrogate Endpoint (SUR): Blood pressure
Study 9572995 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31882376 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29266308 — Predictive Biomarker (PRD): TYK2 mRNA
Genes: TYK2
Study 29266308 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 29266308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23672267 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 18520292 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12687554 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12687554 — Surrogate Endpoint (SUR): Bone mineral density
Study 8911782 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 6109798 — Surrogate Endpoint (SUR): Blood pressure
Study 16715780 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 3121343 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15065482 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 24650839 — Surrogate Endpoint (SUR): Blood pressure
Study 9594263 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23404916 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23876862 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17237480 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 7872717 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 31443939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15058213 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15058213 — Surrogate Endpoint (SUR): Serum calcium
Study 10194144 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 22926460 — Surrogate Endpoint (SUR): Forced vital capacity