TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25483979 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25483979 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19068785 — Surrogate Endpoint (SUR): Bone mineral density
Study 19068785 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19233930 — Predictive Biomarker (PRD): PLXNB1 mRNA
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 15673635 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25888414 — Surrogate Endpoint (SUR): Blood pressure
Study 17263761 — Surrogate Endpoint (SUR): Blood pressure
Study 17263761 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2508417 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2508417 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31562800 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study 23934680 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 23934680 — Safety Biomarker (SAF): Reactive oxygen species
Study 21272992 — Safety Biomarker (SAF): Hyaluronic acid
Study 9140155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26749451 — Surrogate Endpoint (SUR): Blood pressure
Study 30515573 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 24969551 — Surrogate Endpoint (SUR): Blood pressure
Study 22431426 — Surrogate Endpoint (SUR): Bone mineral density
Study 8592249 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2650524 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7419959 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 25264565 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 25264565 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 18035733 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 18035733 — Surrogate Endpoint (SUR): Blood pressure
Study 15720582 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 7768380 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9932756 — Surrogate Endpoint (SUR): Blood pressure
Study 22584554 — Surrogate Endpoint (SUR): Blood pressure
Study 15871132 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 10455474 — Surrogate Endpoint (SUR): Blood pressure
Study 2231320 — Surrogate Endpoint (SUR): Blood pressure
Study 12352271 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 28129020 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28129020 — Surrogate Endpoint (SUR): Blood pressure
Study 22941095 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 10223454 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 594788 — Surrogate Endpoint (SUR): Blood pressure
Study 16499796 — Surrogate Endpoint (SUR): Blood pressure
Study 3134518 — Surrogate Endpoint (SUR): Blood pressure
Study 14594526 — Surrogate Endpoint (SUR): Blood pressure
Study 3911735 — Surrogate Endpoint (SUR): Blood pressure
Study 3911735 — Surrogate Endpoint (SUR): Serum potassium
Study 3911735 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28318688 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25001475 — Surrogate Endpoint (SUR): Blood pressure
Study 28573499 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25084009 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25084009 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 31997577 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 20642580 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 17419879 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10430341 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 30718622 — Surrogate Endpoint (SUR): Blood pressure
Study 21879101 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 17134960 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 17134960 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17134960 — Surrogate Endpoint (SUR): Blood pressure
Study 27604241 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 24912053 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 12870776 — Surrogate Endpoint (SUR): Blood pressure
Study 31167875 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 26944692 — Surrogate Endpoint (SUR): Blood pressure
Study 22075192 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 12495391 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16547531 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10619792 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 10619792 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6091248 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6091248 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31200638 — Surrogate Endpoint (SUR): Blood pressure
Study 9626212 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 3339217 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28665340 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 10866043 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 30740936 — Predictive Biomarker (PRD): ROPN1L mRNA
Genes: ROPN1L; ASP; RSPH11
Study 20200346 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31851385 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22003000 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 30707002 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 27477289 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study 27477289 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 27477289 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 18925413 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12523681 — Surrogate Endpoint (SUR): Blood pressure
Study 31498682 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 28826192 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 26125298 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 22926634 — Surrogate Endpoint (SUR): Blood pressure
Study 19144760 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17551149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11773919 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24119734 — Monitoring Biomarker (MOI): HBV DNA
Study 18271226 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 18271226 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 18271226 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15952402 — Surrogate Endpoint (SUR): Bone mineral density
Study 7596123 — Surrogate Endpoint (SUR): Blood pressure
Study 6489764 — Surrogate Endpoint (SUR): Blood pressure
Study 6489764 — Surrogate Endpoint (SUR): Serum creatinine
Study 15677779 — Surrogate Endpoint (SUR): Blood pressure
Study 11865416 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23905374 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20659908 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 20659908 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16542205 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 16542205 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 16542205 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 16542205 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 15264506 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 9233903 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 3102211 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18700624 — Surrogate Endpoint (SUR): Blood pressure
Study 18558509 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 18558509 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10369196 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23485514 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18163196 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18163196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18163196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18163196 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8144825 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2843314 — Surrogate Endpoint (SUR): Blood pressure
Study 28522759 — Surrogate Endpoint (SUR): Blood pressure
Study 26226987 — Surrogate Endpoint (SUR): Bone mineral density
Study 21216518 — Predictive Biomarker (PRD): CISH mRNA
Genes: CISH; G18
Study 3937367 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29055814 — Surrogate Endpoint (SUR): Blood pressure
Study 22240497 — Surrogate Endpoint (SUR): Blood pressure
Study 11704703 — Surrogate Endpoint (SUR): Blood pressure
Study 2830895 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2830895 — Surrogate Endpoint (SUR): Blood pressure
Study 27110711 — Surrogate Endpoint (SUR): Blood pressure
Study 24727261 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24727261 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30362839 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 28733214 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study 17712121 — Predictive Biomarker (PRD): NPY5R mRNA
Genes: NPY5R; NPYR5
Study 17712121 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 10030325 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10030325 — Surrogate Endpoint (SUR): Blood pressure
Study 8767350 — Surrogate Endpoint (SUR): Blood pressure
Study 6314747 — Surrogate Endpoint (SUR): Blood pressure
Study 30019634 — Surrogate Endpoint (SUR): Blood pressure
Study 24260180 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21131371 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17022853 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8227340 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25385727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 16891991 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 10950398 — Surrogate Endpoint (SUR): Blood pressure
Study 27550880 — Predictive Biomarker (PRD): SP9 mRNA
Genes: SP9
Study 15505637 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11950190 — Predictive Biomarker (PRD): RABGAP1L mRNA
Genes: RABGAP1L; HHL; KIAA0471
Study 791605 — Surrogate Endpoint (SUR): Blood pressure
Study 31831564 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 19386610 — Surrogate Endpoint (SUR): Bone mineral density
Study 15117983 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21029674 — Surrogate Endpoint (SUR): Serum creatinine
Study 15797147 — Surrogate Endpoint (SUR): Blood pressure
Study 8531896 — Surrogate Endpoint (SUR): Blood pressure
Study 22577270 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 22577270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22577270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9781523 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 1108706 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25989270 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 12764804 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 21871667 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 9747746 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9747746 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2265113 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28635557 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28635557 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28635557 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25668581 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 6784982 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 9508013 — Surrogate Endpoint (SUR): Urinary oxalate
Study 8001541 — Surrogate Endpoint (SUR): Plasma ammonia
Study 16784923 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16784923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16784923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9093599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9093599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9093599 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 18198640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18198640 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 9468746 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 7637923 — Surrogate Endpoint (SUR): Blood pressure
Study 9026840 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9026840 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30789207 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 24152086 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22044753 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22044753 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14663300 — Surrogate Endpoint (SUR): Blood pressure
Study 28969887 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 26291594 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 22920158 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 12631373 — Surrogate Endpoint (SUR): Blood pressure
Study 2416297 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 25721356 — Surrogate Endpoint (SUR): Blood pressure
Study 12183217 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 18443134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18443134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18443134 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12544374 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25669214 — Surrogate Endpoint (SUR): Blood pressure
Study 31356558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23931889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21757141 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 11357168 — Safety Biomarker (SAF): Interleukin 1
Study 7525422 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 29549464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29549464 — Surrogate Endpoint (SUR): Serum uric acid
Study 29549464 — Surrogate Endpoint (SUR): Blood pressure
Study 18976959 — Predictive Biomarker (PRD): Hormone receptor
Study 26475166 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 23018435 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23018435 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 23018435 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 20386508 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17084411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17084411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12569761 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25117820 — Predictive Biomarker (PRD): SV2C mRNA
Genes: SV2C; KIAA1054
Study 10774806 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 10774806 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 10774806 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8858279 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19615160 — Predictive Biomarker (PRD): Microsatellite instability
Study 17307663 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 8615057 — Surrogate Endpoint (SUR): Serum triglycerides
Study 15229304 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11249054 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9722129 — Surrogate Endpoint (SUR): Bone mineral density
Study 433813 — Surrogate Endpoint (SUR): Serum sodium
Study 27647261 — Surrogate Endpoint (SUR): Bone mineral density
Study 3513687 — Surrogate Endpoint (SUR): Blood pressure
Study 17481946 — Surrogate Endpoint (SUR): Blood pressure
Study 7607715 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7607715 — Surrogate Endpoint (SUR): Blood pressure
Study 19733706 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19733706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17762662 — Surrogate Endpoint (SUR): Blood pressure
Study 9406880 — Predictive Biomarker (PRD): IL13
Genes: P600; IL-13; ALRH; BHR1; MGC116786; MGC116788; MGC116789
Study 9406880 — Predictive Biomarker (PRD): SEPHS1 mRNA
Genes: SEPHS1; SELD; SPS; SPS1
Study 29539616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12773137 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 24220352 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20726843 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20726843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12023504 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 10463960 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10463960 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 7751683 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 23195668 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 18842392 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12050246 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 10332942 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10332942 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 15196110 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 7838618 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3362274 — Surrogate Endpoint (SUR): Serum potassium
Study 31149841 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31149841 — Surrogate Endpoint (SUR): Blood pressure
Study 19124524 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24986061 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19379491 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 15006949 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 23736111 — Surrogate Endpoint (SUR): Blood pressure
Study 18639296 — Surrogate Endpoint (SUR): Blood pressure
Study 7957001 — Surrogate Endpoint (SUR): Bone mineral density
Study 3592329 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 3592329 — Surrogate Endpoint (SUR): Blood pressure
Study 14557356 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 14557356 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 8930424 — Surrogate Endpoint (SUR): Blood pressure
Study 3771472 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29506504 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 22886853 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 1504055 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27519769 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 27519769 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 7547654 — Surrogate Endpoint (SUR): Blood pressure
Study 11601567 — Surrogate Endpoint (SUR): Serum testosterone
Study 9685822 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 9685822 — Surrogate Endpoint (SUR): Blood pressure
Study 7322958 — Surrogate Endpoint (SUR): Blood pressure
Study 25592188 — Predictive Biomarker (PRD): HR mRNA
Genes: HR