TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20119859 — Predictive Biomarker (PRD): IL15 mRNA
Genes: IL15
Study 18606034 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 12417283 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2200382 — Surrogate Endpoint (SUR): Blood pressure
Study 25980737 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 15519020 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7805356 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 23850318 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12865453 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 12865453 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 8269444 — Surrogate Endpoint (SUR): Blood pressure
Study 22878857 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 22092126 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 22092126 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17035445 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9430084 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9430084 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27687373 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 22759324 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 20083352 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 31482404 — Surrogate Endpoint (SUR): Blood pressure
Study 29409133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20115931 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7898095 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7898095 — Surrogate Endpoint (SUR): Blood pressure
Study 3390235 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26392152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9607117 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7638994 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31780025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31780025 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31780025 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21679318 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18094013 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16877299 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 16877299 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18772807 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18279829 — Safety Biomarker (SAF): Hyaluronic acid
Study 16921034 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 8592524 — Safety Biomarker (SAF): Interleukin 1
Study 1955630 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28976863 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 17151364 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 17151364 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 27542791 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 24401928 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24401928 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20060191 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC2A4 mRNA
Genes: SLC2A4; GLUT4
Study 15486001 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 15486001 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7781792 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 16385874 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 16385874 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 11285326 — Surrogate Endpoint (SUR): Blood pressure
Study 2892336 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 31431112 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 24308728 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17165348 — Surrogate Endpoint (SUR): Blood pressure
Study 17165348 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17062965 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7992901 — Surrogate Endpoint (SUR): Blood pressure
Study 30896603 — Surrogate Endpoint (SUR): Blood pressure
Study 26074331 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19406402 — Safety Biomarker (SAF): c-Jun N-terminal kinase
Study 19406402 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7723344 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 2048592 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28120446 — Surrogate Endpoint (SUR): Blood pressure
Study 25212456 — Predictive Biomarker (PRD): Liver iron
Study 23689577 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23689577 — Surrogate Endpoint (SUR): Serum creatinine
Study 22164271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17244850 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 17244850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15531491 — Surrogate Endpoint (SUR): Bone mineral density
Study 15531491 — Surrogate Endpoint (SUR): Serum calcium
Study 3354541 — Surrogate Endpoint (SUR): Blood pressure
Study 3354541 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31409509 — Surrogate Endpoint (SUR): Blood pressure
Study 26902043 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 23744953 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 20927038 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20927038 — Surrogate Endpoint (SUR): Serum creatinine
Study 19133220 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 19133220 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 14559046 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 1316584 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 1316584 — Surrogate Endpoint (SUR): Blood pressure
Study 14745070 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 21355441 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12580236 — Surrogate Endpoint (SUR): Blood pressure
Study 22240495 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 18796619 — Surrogate Endpoint (SUR): Blood pressure
Study 31172667 — Surrogate Endpoint (SUR): Blood pressure
Study 16837887 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11376503 — Surrogate Endpoint (SUR): Blood pressure
Study 9262843 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8111816 — Surrogate Endpoint (SUR): Blood pressure
Study 20829712 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29508470 — Predictive Biomarker (PRD): FTCD mRNA
Genes: FTCD
Study 22027579 — Surrogate Endpoint (SUR): Serum sodium
Study 22027579 — Surrogate Endpoint (SUR): Serum creatinine
Study 23706413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23706413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15475635 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 10030554 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10030554 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7802191 — Surrogate Endpoint (SUR): Blood pressure
Study 23636649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17161243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17161243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30203756 — Surrogate Endpoint (SUR): Blood pressure
Study 12114340 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study 30571288 — Predictive Biomarker (PRD): SDHA mRNA
Genes: SDHA; SDH2; SDHF
Study 30571288 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 24720551 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24720551 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31886744 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 31886744 — Surrogate Endpoint (SUR): Blood pressure
Study 31886744 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24106806 — Surrogate Endpoint (SUR): Blood pressure
Study 22728905 — Surrogate Endpoint (SUR): Blood pressure
Study 16485521 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16485521 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1866069 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30005843 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 18551024 — Surrogate Endpoint (SUR): Blood pressure
Study 18551024 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15843449 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 15843449 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 12392871 — Surrogate Endpoint (SUR): Blood pressure
Study 23079898 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 16410944 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11845867 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10082500 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10082500 — Surrogate Endpoint (SUR): Serum creatinine
Study 10082500 — Surrogate Endpoint (SUR): Blood pressure
Study 2344090 — Surrogate Endpoint (SUR): Bacterial count
Study 29860057 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 25548124 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 21833720 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 21833720 — Predictive Biomarker (PRD): CASP9 mRNA
Genes: CASP9; MCH6
Study 16713432 — Surrogate Endpoint (SUR): Bone mineral density
Study 24039173 — Predictive Biomarker (PRD): ADAMTS16 mRNA
Genes: ADAMTS16; KIAA2029
Study 21505058 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 18261731 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10470699 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6131760 — Surrogate Endpoint (SUR): Blood pressure
Study 25350119 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16160590 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17516492 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 7763199 — Surrogate Endpoint (SUR): Blood pressure
Study 7028356 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 7028356 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25105367 — Predictive Biomarker (PRD): FCGR2C mRNA
Genes: FCGR2C; CD32; FCG2; IGFR2
Study 22299661 — Surrogate Endpoint (SUR): Blood pressure
Study 22940056 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 22940056 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17047615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17047615 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17047615 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3578255 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 19394473 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16567606 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8442970 — Surrogate Endpoint (SUR): Blood pressure
Study 29943702 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22495111 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10228814 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 18596958 — Monitoring Biomarker (MOI): HBV DNA
Study 12412676 — Surrogate Endpoint (SUR): Serum potassium
Study 10357919 — Safety Biomarker (SAF): Coagulation factor IIa
Genes: F2
Study 29466592 — Predictive Biomarker (PRD): HLF mRNA
Genes: HLF
Study 27197287 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 27197287 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 27197287 — Predictive Biomarker (PRD): SOD3 mRNA
Genes: SOD3
Study 27197287 — Predictive Biomarker (PRD): TXNRD2 mRNA
Genes: TXNRD2; KIAA1652; TRXR2
Study 27197287 — Predictive Biomarker (PRD): SEC14L2 mRNA
Genes: SEC14L2; C22orf6; KIAA1186; KIAA1658
Study 16376753 — Predictive Biomarker (PRD): MXD1 mRNA
Genes: MXD1; MAD
Study 23690338 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23690338 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 8213508 — Surrogate Endpoint (SUR): Serum creatinine
Study 29723592 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29723592 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 29723592 — Surrogate Endpoint (SUR): Blood pressure
Study 29723592 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29723592 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18959679 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10720167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10720167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10720167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1380197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1380197 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 25550337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8789469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8789469 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 383195 — Surrogate Endpoint (SUR): Blood pressure
Study 31754697 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31152327 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31152327 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31152327 — Predictive Biomarker (PRD): Hormone receptor
Study 2688602 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 2688602 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2688602 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25798680 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 11343441 — Surrogate Endpoint (SUR): Blood pressure
Study 27774892 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26442402 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26442402 — Surrogate Endpoint (SUR): Blood pressure
Study 16357312 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16357312 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16357312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16357312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9066316 — Surrogate Endpoint (SUR): Blood pressure
Study 28284202 — Surrogate Endpoint (SUR): Blood pressure
Study 21807618 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 17005501 — Surrogate Endpoint (SUR): Blood pressure
Study 8370370 — Surrogate Endpoint (SUR): Blood pressure
Study 30175329 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30175329 — Surrogate Endpoint (SUR): Probing pocket depth
Study 8730004 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8730004 — Safety Biomarker (SAF): Human leucocyte antigen
Study 21036667 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 21036667 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 8564625 — Surrogate Endpoint (SUR): Blood pressure
Study 31669427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27829371 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20373477 — Predictive Biomarker (PRD): INSIG2 mRNA
Genes: INSIG2
Study 1282465 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 21248294 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 21248294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6117516 — Surrogate Endpoint (SUR): Blood pressure
Study 26647424 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 26647424 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 26647424 — Surrogate Endpoint (SUR): Bone mineral density
Study 25701373 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 12610022 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12610022 — Surrogate Endpoint (SUR): Serum creatinine
Study 28384735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25918454 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 25918454 — Safety Biomarker (SAF): BDNF
Study 21836044 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 10968496 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 9280188 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8315953 — Surrogate Endpoint (SUR): Serum creatinine
Study 8315953 — Surrogate Endpoint (SUR): Blood pressure
Study 27429618 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15326131 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 27815511 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 25837219 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9753527 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 16331635 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 14616412 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 14616412 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 14616412 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19008099 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 19008099 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19008099 — Safety Biomarker (SAF): Interleukin 1
Study 19008099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15081441 — Surrogate Endpoint (SUR): Blood pressure
Study 15081441 — Surrogate Endpoint (SUR): Serum potassium
Study 28609330 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17263930 — Surrogate Endpoint (SUR): Blood pressure
Study 2200253 — Surrogate Endpoint (SUR): Blood pressure
Study 15837247 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 11844743 — Surrogate Endpoint (SUR): Bone mineral density
Study 10357325 — Surrogate Endpoint (SUR): Blood pressure
Study 31658058 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 24211751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14734002 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18191071 — Surrogate Endpoint (SUR): Blood pressure
Study 18191071 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17190179 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1573032 — Surrogate Endpoint (SUR): Blood pressure
Study 27020669 — Predictive Biomarker (PRD): SGK1 mRNA
Genes: SGK1; SGK
Study 19832854 — Surrogate Endpoint (SUR): Bone mineral density
Study 10332129 — Surrogate Endpoint (SUR): Blood pressure
Study 1763923 — Surrogate Endpoint (SUR): Blood pressure
Study 30186817 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 28954926 — Monitoring Biomarker (MOI): HBV DNA
Study 11601117 — Surrogate Endpoint (SUR): Serum creatinine
Study 11601117 — Surrogate Endpoint (SUR): Blood pressure
Study 7740450 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 28485320 — Surrogate Endpoint (SUR): Serum creatinine
Study 15222407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9218208 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2952213 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 26253453 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 26253453 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 26253453 — Safety Biomarker (SAF): miR-1
Study 26253453 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study 23897769 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22739373 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 16046950 — Surrogate Endpoint (SUR): Blood pressure
Study 30796855 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 28489856 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25582225 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 19628651 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16358341 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16358341 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10822123 — Surrogate Endpoint (SUR): Blood pressure
Study 27173369 — Surrogate Endpoint (SUR): Serum creatinine