TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04082949 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04082949 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01118793 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT04019938 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study NCT04019938 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04462068 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04721054 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02780492 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00092625 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00052013 — Predictive Biomarker (PRD): VHL mRNA
Genes: VHL
Study NCT03109288 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study NCT03109288 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03737539 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01692925 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study NCT02143466 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03672474 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT03348280 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00109824 — Predictive Biomarker (PRD): DNMT1 mRNA
Genes: DNMT1; AIM; CXXC9; DNMT
Study NCT00109824 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT04657198 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03046667 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001409 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00001409 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03034148 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT03070535 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT02025543 — Predictive Biomarker (PRD): Liver iron
Study NCT02044055 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04104607 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01177527 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT03914742 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT04537962 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04748744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04748744 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03926091 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02855268 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-21
Genes: MIR21
Study NCT00645697 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00490958 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01543074 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT01980459 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00720291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00498693 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01295593 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01295593 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00713531 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00454558 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00454558 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04524689 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02047838 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT04477564 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study NCT04477564 — Predictive Biomarker (PRD): TET2 mRNA
Genes: TET2; KIAA1546; Nbla00191
Study NCT04477564 — Predictive Biomarker (PRD): ASXL1 mRNA
Genes: ASXL1; KIAA0978
Study NCT04477564 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT04477564 — Predictive Biomarker (PRD): SH2B3 mRNA
Genes: SH2B3; LNK
Study NCT01097967 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01097967 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00697242 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study NCT01902316 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01913457 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01913457 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01548911 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT01388569 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02056626 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05758467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01598077 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04489511 — Predictive Biomarker (PRD): ABCA4 mRNA
Genes: ABCA4; ABCR
Study NCT01433172 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01433172 — Predictive Biomarker (PRD): CCL21 mRNA
Genes: CCL21; SCYA21; UNQ784/PRO1600
Study NCT01914770 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT01914770 — Monitoring Biomarker (MOI): Complement C4
Study NCT03799744 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT04219124 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00914472 — Predictive Biomarker (PRD): TTPA mRNA
Genes: TTPA; TPP1
Study NCT01470456 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00532207 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01965691 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00458120 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01384799 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01384799 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04706468 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT03087136 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT02491008 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02580604 — Surrogate Endpoint (SUR): Serum calcium
Study NCT04622774 — Predictive Biomarker (PRD): ADAM9 mRNA
Genes: ADAM9; KIAA0021; MCMP; MDC9; MLTNG
Study NCT03756103 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03756103 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01813292 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03763019 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00427921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02421614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02421614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01248923 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01250574 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT04514159 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04514159 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04514159 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02829853 — Predictive Biomarker (PRD): CCDC88B mRNA
Genes: CCDC88B; BRLZ
Study NCT03127735 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT01796457 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01290432 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00528138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00528138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03192475 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03595644 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03595644 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00388843 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04014647 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT02448329 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT04114669 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00923507 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT04651868 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT00769379 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04439331 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT04439331 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT00495794 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01292603 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03612336 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00368446 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study NCT03384940 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02084732 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03730558 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00315380 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01174108 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01174108 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01174108 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03598894 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02398643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02398643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01780298 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT02825615 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01458483 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00958269 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02114242 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT02114242 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT04824079 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02179216 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04636333 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04636333 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03471260 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT03471260 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT01785329 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04679168 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04562129 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04562129 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03643510 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01037920 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03717415 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study NCT03281902 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03281902 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03281902 — Predictive Biomarker (PRD): TK1 mRNA
Genes: TK1
Study NCT03281902 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT03281902 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03281902 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04153799 — Predictive Biomarker (PRD): CXCR5 mRNA
Genes: CXCR5; BLR1; MDR15
Study NCT04153799 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04153799 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03931928 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT03931928 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01672775 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT04640792 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT02001935 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT02001935 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study NCT02450513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00293735 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02012504 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT03877523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03877523 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study NCT03877523 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT02404870 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03398005 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00461552 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT03382834 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT04442165 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00032149 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04472013 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03343626 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04022863 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00234923 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03953833 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03166241 — Predictive Biomarker (PRD): IL21
Genes: Za11; IL-21
Study NCT04533321 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04533321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02771717 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00600210 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00600210 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00270218 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03174223 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT00738777 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04807881 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04737720 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study NCT03829826 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00982358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00982358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00982358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03195257 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01358968 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT03131388 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01003691 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05173909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04362995 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02679755 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02679755 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01460134 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study NCT02975050 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01764711 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT02750670 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT05985187 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03899883 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02114346 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01559675 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03953469 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04198480 — Surrogate Endpoint (SUR): Serum calcium
Study NCT04302727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04302727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01089101 — Predictive Biomarker (PRD): KIAA1549 mRNA
Genes: KIAA1549
Study NCT01736293 — Predictive Biomarker (PRD): ABCA4 mRNA
Genes: ABCA4; ABCR
Study NCT03456908 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT04458610 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03212274 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT03212274 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT01929382 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01734681 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04313231 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study NCT04313231 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study NCT04407988 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01478568 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01860833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01860833 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04068103 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01836640 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Plasma DNA
Study NCT01836640 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01836640 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01836640 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02047019 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02952924 — Monitoring Biomarker (MOI): HBV DNA
Study NCT05336578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03623763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06775990 — Predictive Biomarker (PRD): KISS1 mRNA
Genes: KISS1; PP5098
Study NCT06775990 — Predictive Biomarker (PRD): KISS1R mRNA
Genes: KISS1R; AXOR12; GPR54
Study NCT06775990 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT06775990 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT00108862 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04223180 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04223180 — Predictive Biomarker (PRD): 5HTT
Genes: SLC6A4; 5-HTT; SERT1
Study NCT04223180 — Safety Biomarker (SAF): BDNF
Study NCT03580876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01319448 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT04569292 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT02610582 — Predictive Biomarker (PRD): CNGA3 mRNA
Genes: CNGA3; CNCG3
Study NCT02177188 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04004910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01255891 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT04398108 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00687648 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00687648 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01913067 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02990819 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19