TrialPanorama/TrialPanorama-database huggingface dataset:
Study 16118910 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 1691385 — Surrogate Endpoint (SUR): Blood pressure
Study 20817750 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8097802 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8097802 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 3316564 — Surrogate Endpoint (SUR): Serum creatinine
Study 27569936 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 22439742 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 18432175 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22683252 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15777680 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11994976 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11994976 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9414143 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19158153 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17192771 — Surrogate Endpoint (SUR): Blood pressure
Study 25644275 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 25644275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10720881 — Surrogate Endpoint (SUR): Blood pressure
Study 29068321 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 29068321 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 26686695 — Surrogate Endpoint (SUR): Bone mineral density
Study 16706692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11103185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16391587 — Surrogate Endpoint (SUR): Bone mineral density
Study 16391587 — Surrogate Endpoint (SUR): Serum calcium
Study 26520140 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 23735703 — Surrogate Endpoint (SUR): Pathological complete response
Study 18842740 — Surrogate Endpoint (SUR): Blood pressure
Study 10425883 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 22149464 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 22149464 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20798227 — Surrogate Endpoint (SUR): Blood pressure
Study 16135896 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 16135896 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11906322 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 8206687 — Monitoring Biomarker (MOI): HBV DNA
Study 2541740 — Surrogate Endpoint (SUR): Serum creatinine
Study 4837835 — Predictive Biomarker (PRD): OGT mRNA
Genes: OGT
Study 26202452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21861995 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 21861995 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 16680924 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 16680924 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16680924 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2766180 — Surrogate Endpoint (SUR): Blood pressure
Study 7604138 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 23547816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7984597 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 29898853 — Surrogate Endpoint (SUR): Blood pressure
Study 24530944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19411667 — Surrogate Endpoint (SUR): Blood pressure
Study 17311540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17311540 — Surrogate Endpoint (SUR): Serum sodium
Study 29848776 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 29848776 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 6764605 — Surrogate Endpoint (SUR): Blood pressure
Study 19451213 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 19451213 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 19451213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19451213 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12879472 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 12879472 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 23000080 — Surrogate Endpoint (SUR): Blood pressure
Study 21784767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21784767 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16364829 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16364829 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16364829 — Surrogate Endpoint (SUR): Blood pressure
Study 12059866 — Surrogate Endpoint (SUR): Blood pressure
Study 6139346 — Surrogate Endpoint (SUR): Blood pressure
Study 22374556 — Safety Biomarker (SAF): Urinary microalbumin
Study 22374556 — Surrogate Endpoint (SUR): Serum creatinine
Study 20131188 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29745434 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 30650286 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30650286 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15684293 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 31242976 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25344383 — Predictive Biomarker (PRD): ADAM10 mRNA
Genes: ADAM10; KUZ; MADM
Study 25344383 — Pharmacodynamic Biomarker (PDY): Amyloid beta peptide (1-40)
Genes: APP; A4; AD1
Study 12911186 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8287938 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21466389 — Surrogate Endpoint (SUR): Blood pressure
Study 18543485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18543485 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18284032 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 28903738 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24378824 — Predictive Biomarker (PRD): S100A8 mRNA
Genes: S100A8; CAGA; CFAG; MRP8
Study 24378824 — Predictive Biomarker (PRD): Calgranulin B
Genes: S100A9; CAGB; CFAG; MRP14
Study 15709663 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 6812230 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31780429 — Surrogate Endpoint (SUR): Blood pressure
Study 30611335 — Safety Biomarker (SAF): Hyaluronic acid
Study 9990362 — Surrogate Endpoint (SUR): Serum creatinine
Study 7835207 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 23670354 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23670354 — Surrogate Endpoint (SUR): Blood pressure
Study 23670354 — Surrogate Endpoint (SUR): Serum potassium
Study 21107585 — Surrogate Endpoint (SUR): Blood pressure
Study 21107585 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21107585 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11334097 — Surrogate Endpoint (SUR): Blood pressure
Study 31911179 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 31911179 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 31911179 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31911179 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 21480939 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 21480939 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 21480939 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21480939 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 19797730 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 6517973 — Surrogate Endpoint (SUR): Blood pressure
Study 11248773 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 25943912 — Predictive Biomarker (PRD): AKTIP mRNA
Genes: AKTIP; FTS
Study 17940144 — Predictive Biomarker (PRD): SLMAP mRNA
Genes: SLMAP; KIAA1601; SLAP; UNQ1847/PRO3577
Study 16798472 — Predictive Biomarker (PRD): NAPA mRNA
Genes: NAPA; SNAPA
Study 30446398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 28479909 — Surrogate Endpoint (SUR): Blood pressure
Study 28479909 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10981083 — Surrogate Endpoint (SUR): Blood pressure
Study 31726494 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 25773496 — Predictive Biomarker (PRD): HCAR2 mRNA
Genes: HCAR2; GPR109A; HCA2; HM74A; NIACR1
Study 17222813 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17222813 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study 11740293 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9241004 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 31625041 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 31625041 — Surrogate Endpoint (SUR): Blood pressure
Study 6851195 — Surrogate Endpoint (SUR): Blood pressure
Study 26332293 — Surrogate Endpoint (SUR): Serum creatinine
Study 19282374 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 16961669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16961669 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 16961669 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15717708 — Surrogate Endpoint (SUR): Blood pressure
Study 11762556 — Surrogate Endpoint (SUR): Blood pressure
Study 25711332 — Surrogate Endpoint (SUR): Bone mineral density
Study 19544679 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16635205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10933570 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10933570 — Surrogate Endpoint (SUR): Blood pressure
Study 9192124 — Surrogate Endpoint (SUR): Blood pressure
Study 9192124 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7901342 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15931231 — Safety Biomarker (SAF): Interleukin 1 alpha
Genes: IL1A; IL1F1
Study 15931231 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 10532204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10532204 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10532204 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8679463 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 8679463 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 22296885 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 22296885 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21434529 — Monitoring Biomarker (MOI): HBV DNA
Study 15670485 — Predictive Biomarker (PRD): CEACAM6 mRNA
Genes: CEACAM6; NCA
Study 2142858 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31841744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31841744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27967294 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 12439363 — Predictive Biomarker (PRD): RCN1 mRNA
Genes: RCN1; RCN
Study 9129960 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 7893582 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7893582 — Surrogate Endpoint (SUR): Blood pressure
Study 2850682 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2850682 — Surrogate Endpoint (SUR): Serum sodium
Study 2850682 — Surrogate Endpoint (SUR): Serum creatinine
Study 27676398 — Surrogate Endpoint (SUR): Serum calcium
Study 22651572 — Surrogate Endpoint (SUR): Blood pressure
Study 9698957 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 26609965 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26609965 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26609965 — Surrogate Endpoint (SUR): Blood pressure
Study 23912917 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17784949 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 7768135 — Surrogate Endpoint (SUR): Blood pressure
Study 3263812 — Surrogate Endpoint (SUR): Blood pressure
Study 26055239 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 20467622 — Safety Biomarker (SAF): Hyaluronic acid
Study 8647479 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25482832 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16776916 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 16776916 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15600384 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12469157 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6511154 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23281382 — Monitoring Biomarker (MOI): HBV DNA
Study 20179232 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 20179232 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 2146885 — Surrogate Endpoint (SUR): Blood pressure
Study 10025899 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 7740509 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 31597662 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31597662 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 31597662 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 8919037 — Predictive Biomarker (PRD): Phospholipase A2 inhibitory protein
Genes: ANXA1; ANX1; LPC1
Study 31443692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11791023 — Surrogate Endpoint (SUR): Blood pressure
Study 10347347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 1934538 — Surrogate Endpoint (SUR): Blood pressure
Study 24836205 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study 22854665 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 17040921 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 15090932 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 1558774 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31767581 — Surrogate Endpoint (SUR): Blood pressure
Study 31767581 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31767581 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26831541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9856375 — Surrogate Endpoint (SUR): Blood pressure
Study 7654468 — Surrogate Endpoint (SUR): Bone mineral density
Study 10225080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30697471 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 30697471 — Surrogate Endpoint (SUR): Blood pressure
Study 30697471 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30081574 — Surrogate Endpoint (SUR): Blood pressure
Study 25064674 — Surrogate Endpoint (SUR): Blood pressure
Study 25064674 — Surrogate Endpoint (SUR): Serum creatinine
Study 22863216 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 22863216 — Predictive Biomarker (PRD): IL12A mRNA
Genes: IL12A; NKSF1
Study 22863216 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 12 beta
Genes: IL12B; NKSF2
Study 22863216 — Safety Biomarker (SAF): Interleukin 12
Study 19604407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19604407 — Surrogate Endpoint (SUR): Blood pressure
Study 19604407 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17805239 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17805239 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16617930 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11333173 — Predictive Biomarker (PRD): SCN5A mRNA
Genes: SCN5A
Study 25525743 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25525743 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 25525743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 6247656 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 27409593 — Surrogate Endpoint (SUR): Blood pressure
Study 20459744 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 20459744 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20459744 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20459744 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 20459744 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 20459744 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 20459744 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 20459744 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 17623763 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 30687550 — Surrogate Endpoint (SUR): Blood pressure
Study 22544914 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18672990 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 8967667 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1653773 — Predictive Biomarker (PRD): LTB mRNA
Genes: LTB; TNFC; TNFSF3
Study 1653773 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25211703 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 25211703 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 25211703 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 7653448 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30738047 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30738047 — Safety Biomarker (SAF): miR-30a-5p
Genes: MIR30A
Study 30738047 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 30738047 — Safety Biomarker (SAF): miR-200a
Genes: MIR200A
Study 30738047 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study 30738047 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30738047 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 30738047 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 18551007 — Surrogate Endpoint (SUR): Blood pressure
Study 1457695 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28523988 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 19417018 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15899921 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 12645187 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9594864 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 12475460 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12475460 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12475460 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12475460 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9808096 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9808096 — Surrogate Endpoint (SUR): Blood pressure
Study 30715214 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 30715214 — Predictive Biomarker (PRD): ZFPM2 mRNA
Genes: ZFPM2; FOG2; ZNF89B
Study 30715214 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30715214 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 30715214 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30715214 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-143
Genes: MIR143
Study 30715214 — Predictive Biomarker (PRD): miR-145
Genes: MIR145
Study 26123789 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21866656 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 8198625 — Surrogate Endpoint (SUR): Blood pressure
Study 26177348 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 23635560 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL