TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04097704 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT04221308 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00278083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02810392 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02060604 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01537744 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT03303378 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT03522974 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03195543 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03195543 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT01687959 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT02945033 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01834014 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02042248 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01721421 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03282188 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03043989 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01519960 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00954902 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05125510 — Predictive Biomarker (PRD): ZMYM2 mRNA
Genes: ZMYM2; FIM; RAMP; ZNF198
Study NCT05125510 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study NCT05125510 — Predictive Biomarker (PRD): BCAR1 mRNA
Genes: BCAR1; CAS; CASS1; CRKAS
Study NCT03301038 — Predictive Biomarker (PRD): CYP24A1 mRNA
Genes: CYP24A1; CYP24
Study NCT03301038 — Surrogate Endpoint (SUR): Serum calcium
Study NCT04830787 — Predictive Biomarker (PRD): MYBPC3 mRNA
Genes: MYBPC3
Study NCT04830787 — Predictive Biomarker (PRD): MYH7 mRNA
Genes: MYH7; MYHCB
Study NCT04830787 — Predictive Biomarker (PRD): ACTC1 mRNA
Genes: ACTC1; ACTC
Study NCT01375777 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00230464 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT00230464 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00230464 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03839212 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01857466 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT03540147 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02750592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03512314 — Predictive Biomarker (PRD): NLRC4 mRNA
Genes: NLRC4; CARD12; CLAN; CLAN1; IPAF; UNQ6189/PRO20215
Study NCT03512314 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study NCT00562939 — Predictive Biomarker (PRD): TLR9
Genes: CD289
Study NCT00366158 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT05757921 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT02576561 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study NCT02615054 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03287804 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT00226954 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01411709 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00456547 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study NCT04061811 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study NCT00961844 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT00749372 — Predictive Biomarker (PRD): Liver iron
Study NCT00641862 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT03402685 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05008250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01019642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04977089 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04977089 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04977089 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04768491 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04275674 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT01272388 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT00647452 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00647452 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00947804 — Predictive Biomarker (PRD): SACS mRNA
Genes: SACS; KIAA0730
Study NCT03539497 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT03539497 — Safety Biomarker (SAF): Cytochrome c
Study NCT03944499 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01233193 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01608919 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT03861286 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT01645397 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00739700 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02775123 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02775123 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT03869411 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study NCT00358722 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT00608387 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02030847 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02444884 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT00003588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01995565 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00664924 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05145088 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00049751 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02389335 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT02389335 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02551926 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00464932 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT00765921 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03823261 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02469454 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study NCT00310531 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02484963 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00947479 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03347006 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00866684 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study NCT02045576 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02951156 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03582020 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04573595 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01946373 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT05476341 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT05476341 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT05546047 — Predictive Biomarker (PRD): DNAJB9 mRNA
Genes: DNAJB9; MDG1; UNQ743/PRO1471
Study NCT03879382 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03879382 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03741660 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05348161 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03106155 — Predictive Biomarker (PRD): RICTOR mRNA
Genes: RICTOR; KIAA1999
Study NCT00495833 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02218710 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00199927 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02493673 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01843764 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT02576288 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT04424017 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00946712 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04562285 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03110250 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT03144674 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT01848756 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03158051 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00428441 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00480272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03060239 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study NCT00254540 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03480659 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study NCT03597854 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04577937 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT03796780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03796780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03674918 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02165020 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04463550 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT04463550 — Predictive Biomarker (PRD): AQP4 mRNA
Genes: AQP4
Study NCT00002546 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT03854617 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00687765 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT02347267 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00946426 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02044744 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00531024 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00531024 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01273402 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT03760796 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01388088 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01384604 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study NCT00144937 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00144937 — Surrogate Endpoint (SUR): Serum triglycerides
Study NCT04037709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04037709 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00226096 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02322905 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00003183 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04387942 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01679652 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06328465 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06328465 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00314210 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT01089270 — Pharmacodynamic Biomarker (PDY): Leucine-rich repeat kinase 2
Genes: LRRK2; PARK8
Study NCT01089270 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study NCT02100189 — Predictive Biomarker (PRD): SH3PXD2A mRNA
Genes: SH3PXD2A; FISH; KIAA0418; SH3MD1; TKS5
Study NCT00669292 — Predictive Biomarker (PRD): TTK mRNA
Genes: TTK; MPS1; MPS1L1
Study NCT00669292 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT00975130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03205410 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT03205410 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04164615 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04164615 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT02877823 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01730209 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT01730209 — Predictive Biomarker (PRD): TSC1
Genes: KIAA0243; LAM; hamartin
Study NCT03134027 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03233906 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03189758 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02308254 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04007861 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02115711 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04407312 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03089606 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study NCT01482247 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02426073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02426073 — Safety Biomarker (SAF): Interleukin 1
Study NCT02426073 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02426073 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study NCT02426073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00129493 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04097093 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT04097093 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study NCT02692781 — Predictive Biomarker (PRD): GCG mRNA
Genes: GCG
Study NCT04142554 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04142554 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02176850 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03439670 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02283047 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02225756 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02526940 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02526940 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00458523 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT03623100 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT01116830 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study NCT03792841 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00586807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00877500 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03322449 — Predictive Biomarker (PRD): APOA2 mRNA
Genes: APOA2
Study NCT02152995 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT01754545 — Predictive Biomarker (PRD): ADAMTS13 mRNA
Genes: ADAMTS13; C9orf8; UNQ6102/PRO20085
Study NCT01015794 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02518659 — Predictive Biomarker (PRD): TRPM6 mRNA
Genes: TRPM6; CHAK2
Study NCT02390752 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT03672253 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT04340076 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study NCT00999817 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT04022876 — Predictive Biomarker (PRD): MDM4 mRNA
Genes: MDM4; MDMX
Study NCT04022876 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT04022876 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01181570 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03875924 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02884622 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT00610857 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03703492 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT03703492 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT03809871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04547504 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT04547504 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04547504 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03379688 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04045587 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT04635241 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03152474 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00884793 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03663699 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02579941 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT03379428 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00768716 — Predictive Biomarker (PRD): SULT1A1 mRNA
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study NCT00768716 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study NCT01509937 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04232085 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study NCT01883297 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04611048 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study NCT03108222 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT01812707 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01812707 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00362258 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03761849 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT00965302 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02655536 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04399798 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study NCT02873442 — Predictive Biomarker (PRD): ADAM17 mRNA
Genes: ADAM17; CSVP; TACE
Study NCT01323335 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01154842 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01523678 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04457245 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00789295 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study NCT02971527 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04364711 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00292955 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00292955 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00631618 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT04605159 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00603850 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT05007223 — Predictive Biomarker (PRD): ATP2C1 mRNA
Genes: ATP2C1; KIAA1347; PMR1L; HUSSY-28
Study NCT04355026 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT04355026 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03000686 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT03000686 — Pharmacodynamic Biomarker (PDY): RAS peptides
Study NCT01785108 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00225212 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00100646 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02532569 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02726334 — Predictive Biomarker (PRD): LGR5 mRNA
Genes: LGR5; GPR49; GPR67
Study NCT03919006 — Safety Biomarker (SAF): Netrin-1
Genes: NTN1; NTN1L