TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15714213 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12093062 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30537846 — Surrogate Endpoint (SUR): Blood pressure
Study 30537846 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24786925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12057861 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 7734353 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 7734353 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 27274715 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 10439009 — Predictive Biomarker (PRD): DAZ1 mRNA
Genes: DAZ1; DAZ; SPGY
Study 7541358 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 22440336 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 22440336 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22440336 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 22440336 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 17898251 — Surrogate Endpoint (SUR): Blood pressure
Study 8003098 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 19917850 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 19917850 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16825703 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 24039182 — Predictive Biomarker (PRD): DYRK1A mRNA
Genes: DYRK1A; DYRK; MNB; MNBH
Study 22183086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22183086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22183086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18448328 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 18448328 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 9081105 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9081105 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8228636 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8228636 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 20864814 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24205043 — Surrogate Endpoint (SUR): Blood pressure
Study 22177466 — Surrogate Endpoint (SUR): Blood pressure
Study 16728212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16728212 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11704596 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 9393380 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28863595 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 12631604 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12631604 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26818781 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18855530 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18855530 — Surrogate Endpoint (SUR): Blood pressure
Study 12196747 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 7864722 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2532463 — Surrogate Endpoint (SUR): Blood pressure
Study 28366698 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): GZMB mRNA
Genes: GZMB; CGL1; CSPB; CTLA1; GRB
Study 28366698 — Predictive Biomarker (PRD): PRF1 mRNA
Genes: PRF1; PFP
Study 28366698 — Predictive Biomarker (PRD): PRF1
Genes: PFP; P1; HPLH2
Study 28366698 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22739125 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study 8467026 — Surrogate Endpoint (SUR): Blood pressure
Study 22117892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20179007 — Surrogate Endpoint (SUR): Serum creatinine
Study 20179007 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18568325 — Predictive Biomarker (PRD): PCLAF mRNA
Genes: PCLAF; KIAA0101; NS5ATP9; PAF; L5
Study 10353071 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10353071 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8207740 — Surrogate Endpoint (SUR): Blood pressure
Study 24372225 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 18706557 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18706557 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18706557 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 18706557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17127043 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 20451585 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 20451585 — Predictive Biomarker (PRD): EDAR mRNA
Genes: EDAR; DL
Study 15520843 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 7676685 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 24658473 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 21068096 — Safety Biomarker (SAF): Hyaluronic acid
Study 17534686 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17534686 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16701925 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16701925 — Safety Biomarker (SAF): Interleukin 12
Study 1825503 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31455871 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 31455871 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 24366288 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23078196 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 11452249 — Predictive Biomarker (PRD): Hormone receptor
Study 21338535 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 10404804 — Surrogate Endpoint (SUR): Bone mineral density
Study 8527541 — Surrogate Endpoint (SUR): Serum creatinine
Study 31888713 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 23408834 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study 19371934 — Surrogate Endpoint (SUR): Blood pressure
Study 15093992 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 15093992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15093992 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 11250999 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9385483 — Surrogate Endpoint (SUR): Blood pressure
Study 8487048 — Predictive Biomarker (PRD): PSD4 mRNA
Genes: PSD4; EFA6B; TIC
Study 3440390 — Surrogate Endpoint (SUR): Blood pressure
Study 2403586 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2403586 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30541021 — Predictive Biomarker (PRD): UST mRNA
Genes: UST; DS2ST
Study 30541021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27911486 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25935165 — Predictive Biomarker (PRD): LAT mRNA
Genes: LAT
Study 22288296 — Surrogate Endpoint (SUR): Blood pressure
Study 29232323 — Predictive Biomarker (PRD): TKTL1 mRNA
Genes: TKTL1; TKR; TKT2
Study 26338457 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 11978257 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 10319057 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7611579 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31542304 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 31542304 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 30012675 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study 27718847 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 27718847 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 25201708 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11932266 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31667987 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28317660 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 25290743 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 15376463 — Surrogate Endpoint (SUR): Blood pressure
Study 6749348 — Surrogate Endpoint (SUR): Blood pressure
Study 29059253 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26362564 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24363555 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10432132 — Surrogate Endpoint (SUR): Bone mineral density
Study 25770310 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 20498215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8555493 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 8555493 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 8555493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7002524 — Surrogate Endpoint (SUR): Blood pressure
Study 30585438 — Predictive Biomarker (PRD): SPATS2L mRNA
Genes: SPATS2L; DNAPTP6; SP1224
Study 26714385 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7974373 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31331789 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15154956 — Surrogate Endpoint (SUR): Blood pressure
Study 9516090 — Surrogate Endpoint (SUR): Forced vital capacity
Study 4394369 — Surrogate Endpoint (SUR): Blood pressure
Study 26660720 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16284584 — Predictive Biomarker (PRD): SRM mRNA
Genes: SRM; SPS1; SRML1
Study 7716196 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 23933545 — Surrogate Endpoint (SUR): Blood pressure
Study 1488568 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23811290 — Safety Biomarker (SAF): Reactive oxygen species
Study 20206794 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 20206794 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 20513105 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 15812204 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 12459648 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 7503007 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30426192 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 21035513 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19738091 — Surrogate Endpoint (SUR): Serum creatinine
Study 19738091 — Surrogate Endpoint (SUR): Blood pressure
Study 11226092 — Surrogate Endpoint (SUR): Serum sodium
Study 2846291 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 1097149 — Surrogate Endpoint (SUR): Blood pressure
Study 25944732 — Surrogate Endpoint (SUR): Serum creatinine
Study 21771973 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 18957811 — Surrogate Endpoint (SUR): Blood pressure
Study 29949330 — Monitoring Biomarker (MOI): Procalcitonin
Study 24162556 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15877288 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15877288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14749150 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 14749150 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8859934 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8859934 — Surrogate Endpoint (SUR): Blood pressure
Study 1516991 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 1516991 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 12945134 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 1534089 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 16940700 — Surrogate Endpoint (SUR): Blood pressure
Study 16940700 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16940700 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11173715 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 1490224 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 29354672 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21450995 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21450995 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 12835081 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12835081 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12835081 — Surrogate Endpoint (SUR): Serum creatinine
Study 29945674 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20202105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20202105 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10335722 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 8951188 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31786279 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 31786279 — Predictive Biomarker (PRD): UBC mRNA
Genes: UBC
Study 17224471 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17224471 — Surrogate Endpoint (SUR): Blood pressure
Study 14962150 — Surrogate Endpoint (SUR): Blood pressure
Study 11130603 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30833371 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 11127759 — Surrogate Endpoint (SUR): Bone mineral density
Study 10577432 — Surrogate Endpoint (SUR): Blood pressure
Study 2614056 — Surrogate Endpoint (SUR): Blood pressure
Study 305734 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 31863561 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 28390688 — Safety Biomarker (SAF): Hyaluronic acid
Study 15014015 — Predictive Biomarker (PRD): GATM mRNA
Genes: GATM; AGAT
Study 16855170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16855170 — Predictive Biomarker (PRD): CHGA mRNA
Genes: CHGA
Study 11286539 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11286539 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 3263890 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 3263890 — Surrogate Endpoint (SUR): Serum calcium
Study 3263890 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 25567656 — Surrogate Endpoint (SUR): Blood pressure
Study 21443994 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12911327 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3300762 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21120152 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 17846044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17846044 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12743142 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22130786 — Surrogate Endpoint (SUR): Serum calcium
Study 22130786 — Surrogate Endpoint (SUR): Bone mineral density
Study 19875998 — Surrogate Endpoint (SUR): Blood pressure
Study 19875998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2091623 — Surrogate Endpoint (SUR): Blood pressure
Study 31038809 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 31038809 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 28688514 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 28688514 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 1574966 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 26372451 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 19364291 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 19364291 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 19364291 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 19364291 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 16133044 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 10628766 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 26805435 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 7641409 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 7641409 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21235821 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 15900307 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15900307 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15900307 — Surrogate Endpoint (SUR): Blood pressure
Study 12802453 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9796889 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9796889 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27965180 — Surrogate Endpoint (SUR): Blood pressure
Study 23477506 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23477506 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21566054 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8989173 — Surrogate Endpoint (SUR): Serum triglycerides
Study 3318461 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 29540324 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 29540324 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 27042193 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 27042193 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 11095657 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 11095657 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 9123711 — Surrogate Endpoint (SUR): Blood pressure
Study 29921153 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27095306 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 8703646 — Surrogate Endpoint (SUR): Blood pressure
Study 26403745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26403745 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26403745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 7942668 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 22187388 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22187388 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22187388 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17805230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17805230 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 2951823 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26227186 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24079283 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24079283 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29926514 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9651905 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29501590 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 29501590 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 29501590 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26799247 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26799247 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 16002030 — Surrogate Endpoint (SUR): Blood pressure
Study 25851383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25851383 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF