TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17353132 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 16288118 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7734138 — Surrogate Endpoint (SUR): Blood pressure
Study 23471234 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9100162 — Surrogate Endpoint (SUR): Blood pressure
Study 8261692 — Surrogate Endpoint (SUR): Blood pressure
Study 3511691 — Surrogate Endpoint (SUR): Blood pressure
Study 30041437 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 27936999 — Surrogate Endpoint (SUR): Blood pressure
Study 25166215 — Surrogate Endpoint (SUR): Blood pressure
Study 15383088 — Surrogate Endpoint (SUR): Blood pressure
Study 15383088 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30001179 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study 24318863 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 24318863 — Predictive Biomarker (PRD); Safety Biomarker (SAF): GSTP1
Genes: GSTP
Study 2472826 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 17536122 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17536122 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 29843755 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23418958 — Surrogate Endpoint (SUR): Blood pressure
Study 22029856 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 22029856 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 22029856 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 1351888 — Surrogate Endpoint (SUR): Blood pressure
Study 6584561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29031390 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 20880729 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20880729 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 12390994 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 22985580 — Surrogate Endpoint (SUR): Bone mineral density
Study 11789395 — Surrogate Endpoint (SUR): Blood pressure
Study 11789395 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2442551 — Surrogate Endpoint (SUR): Blood pressure
Study 28899914 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22039086 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 9532410 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31576915 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7486614 — Surrogate Endpoint (SUR): Blood pressure
Study 964056 — Surrogate Endpoint (SUR): Bacterial count
Study 19667268 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 19667268 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10806696 — Surrogate Endpoint (SUR): Blood pressure
Study 1996187 — Surrogate Endpoint (SUR): Blood pressure
Study 6434435 — Surrogate Endpoint (SUR): Serum testosterone
Study 29524476 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 23307827 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 16855141 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 21533995 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 12514658 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12514658 — Surrogate Endpoint (SUR): Blood pressure
Study 8698756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17628232 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29147969 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29147969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 29147969 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 29147969 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29147969 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29147969 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24742322 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study 20805433 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 8866698 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 6438014 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25272965 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 24136890 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 16617400 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24595632 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22866767 — Surrogate Endpoint (SUR): Blood pressure
Study 12392586 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10543321 — Surrogate Endpoint (SUR): Blood pressure
Study 2125243 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26233594 — Safety Biomarker (SAF): Hyaluronic acid
Study 11996943 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15840675 — Surrogate Endpoint (SUR): Bone mineral density
Study 15840675 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29233615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29233615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21357381 — Predictive Biomarker (PRD): Microsatellite instability
Study 15253741 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3443058 — Surrogate Endpoint (SUR): Blood pressure
Study 12570114 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1902159 — Surrogate Endpoint (SUR): Blood pressure
Study 27753201 — Surrogate Endpoint (SUR): Blood pressure
Study 29143667 — Predictive Biomarker (PRD): ALAS2 mRNA
Genes: ALAS2; ALASE; ASB
Study 29143667 — Predictive Biomarker (PRD): BCL2L1 mRNA
Genes: BCL2L1; BCL2L; BCLX
Study 29143667 — Predictive Biomarker (PRD): DCAF12 mRNA
Genes: DCAF12; KIAA1892; TCC52; WDR40A
Study 29143667 — Predictive Biomarker (PRD): EPB42 mRNA
Genes: EPB42; E42P
Study 29143667 — Predictive Biomarker (PRD): GMPR mRNA
Genes: GMPR; GMPR1
Study 29143667 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 29143667 — Predictive Biomarker (PRD): TMOD1 mRNA
Genes: TMOD1; D9S57E; TMOD
Study 29143667 — Predictive Biomarker (PRD): TRIM58 mRNA
Genes: TRIM58
Study 29143667 — Predictive Biomarker (PRD): CD247 mRNA
Genes: CD247; CD3Z; T3Z; TCRZ
Study 23336474 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15281530 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 15281530 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27832977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23433430 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 23433430 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 21250913 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 19318900 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17365992 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 30719632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23736112 — Surrogate Endpoint (SUR): Blood pressure
Study 7718899 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29741558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29741558 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8815692 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3910768 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3910768 — Surrogate Endpoint (SUR): Blood pressure
Study 30486575 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30486575 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 22854666 — Monitoring Biomarker (MOI): HBV DNA
Study 16036433 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 16036433 — Safety Biomarker (SAF): BDNF
Study 10676043 — Surrogate Endpoint (SUR): Bone mineral density
Study 31801155 — Predictive Biomarker (PRD): HRC mRNA
Genes: HRC; HCP
Study 17384205 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16088080 — Surrogate Endpoint (SUR): Blood pressure
Study 12106923 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 12106923 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12106923 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10579259 — Surrogate Endpoint (SUR): Blood pressure
Study 1858944 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21209539 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21209539 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 21209539 — Surrogate Endpoint (SUR): Blood pressure
Study 31275984 — Predictive Biomarker (PRD): MUC22 mRNA
Genes: MUC22; G4; PBMUCL1
Study 31275984 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31275984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26796803 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 24525690 — Predictive Biomarker (PRD): GRIK1 mRNA
Genes: GRIK1; GLUR5
Study 15718405 — Predictive Biomarker (PRD): ACTN3 mRNA
Genes: ACTN3
Study 27919222 — Predictive Biomarker (PRD): PDPN mRNA
Genes: PDPN; GP36; PSEC0003; PSEC0025
Study 8826928 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 24983892 — Predictive Biomarker (PRD): SNAP25 mRNA
Genes: SNAP25; SNAP
Study 11095454 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 9050888 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23592605 — Surrogate Endpoint (SUR): Blood pressure
Study 20872345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20872345 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12783932 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12783932 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12783932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12783932 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12783932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22069289 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14514747 — Surrogate Endpoint (SUR): Bone mineral density
Study 9091692 — Surrogate Endpoint (SUR): Blood pressure
Study 7692636 — Surrogate Endpoint (SUR): Serum creatinine
Study 7692636 — Surrogate Endpoint (SUR): Blood pressure
Study 12142115 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12142115 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 7790321 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 31684880 — Surrogate Endpoint (SUR): Blood pressure
Study 23149871 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 15242012 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15242012 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 19049698 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 6353433 — Surrogate Endpoint (SUR): Blood pressure
Study 26068514 — Surrogate Endpoint (SUR): Blood pressure
Study 29207087 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 29207087 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28627356 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 26286137 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26286137 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26286137 — Surrogate Endpoint (SUR): Blood pressure
Study 23135868 — Surrogate Endpoint (SUR): Blood pressure
Study 21417623 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 19046244 — Surrogate Endpoint (SUR): Blood pressure
Study 12763375 — Monitoring Biomarker (MOI): HBV DNA
Study 31340094 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study 31340094 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 27239035 — Predictive Biomarker (PRD): NELFCD mRNA
Genes: NELFCD; NELFD; TH1; TH1L; HSPC130
Study 17362556 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17362556 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17362556 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16379601 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10459959 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20702754 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 7636054 — Surrogate Endpoint (SUR): Forced vital capacity
Study 322905 — Surrogate Endpoint (SUR): Blood pressure
Study 26394188 — Predictive Biomarker (PRD): AJAP1 mRNA
Genes: AJAP1; MOT8; SHREW1
Study 26394188 — Predictive Biomarker (PRD): PAX3 mRNA
Genes: PAX3; HUP2
Study 26394188 — Predictive Biomarker (PRD): EPHA4 mRNA
Genes: EPHA4; HEK8; SEK; TYRO1
Study 26394188 — Predictive Biomarker (PRD): LBX1 mRNA
Genes: LBX1; LBX1H
Study 15328251 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15328251 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 9492500 — Surrogate Endpoint (SUR): Blood pressure
Study 16133638 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 16133638 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 16133638 — Surrogate Endpoint (SUR): Bone mineral density
Study 12234091 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 26452709 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 22924372 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 22924372 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15249567 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9363379 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9363379 — Surrogate Endpoint (SUR): Blood pressure
Study 30924492 — Surrogate Endpoint (SUR): Bone mineral density
Study 29079379 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27616196 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 20697947 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 28019010 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 28019010 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 21479690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21479690 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17710800 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15125121 — Surrogate Endpoint (SUR): Bone mineral density
Study 11246059 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7512100 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 27333970 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 25042878 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25042878 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22750403 — Surrogate Endpoint (SUR): Bone mineral density
Study 19325050 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 20721651 — Surrogate Endpoint (SUR): Serum creatinine
Study 11956264 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2375296 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2375296 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23635331 — Surrogate Endpoint (SUR): Blood pressure
Study 17116511 — Surrogate Endpoint (SUR): Bone mineral density
Study 23418822 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 16927766 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 8836757 — Surrogate Endpoint (SUR): Blood pressure
Study 30537951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24211360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24211360 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21178592 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 18326593 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18326593 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28049699 — Surrogate Endpoint (SUR): Blood pressure
Study 7856290 — Predictive Biomarker (PRD): CLSTN1 mRNA
Genes: CLSTN1; CS1; KIAA0911
Study 7856290 — Predictive Biomarker (PRD): CLSTN3 mRNA
Genes: CLSTN3; CS3; KIAA0726
Study 7856290 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 30988133 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26961091 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25549193 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 28952176 — Predictive Biomarker (PRD): TRPM8 mRNA
Genes: TRPM8; LTRPC6; TRPP8
Study 25676011 — Surrogate Endpoint (SUR): Serum uric acid
Study 25676011 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 25676011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25676011 — Surrogate Endpoint (SUR): Serum creatinine
Study 31837264 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 29098426 — Surrogate Endpoint (SUR): Blood pressure
Study 28132008 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 23333772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23333772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23333772 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23333772 — Safety Biomarker (SAF): IL-6 and IL-10
Study 23333772 — Surrogate Endpoint (SUR): Blood pressure
Study 17054068 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28483270 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 17280633 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17280633 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11240976 — Surrogate Endpoint (SUR): Blood pressure
Study 8923781 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 1098177 — Predictive Biomarker (PRD): OPN1SW mRNA
Genes: OPN1SW; BCP
Study 25527736 — Safety Biomarker (SAF): Reactive oxygen species
Study 10659875 — Surrogate Endpoint (SUR): Undetectable plasma HIV RNA
Study 4063284 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22922564 — Surrogate Endpoint (SUR): Serum creatinine
Study 15252741 — Predictive Biomarker (PRD): CARD16 mRNA
Genes: CARD16; COP; COP1
Study 23411106 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 23411106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11906441 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 11906441 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 11906441 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9731794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2897812 — Surrogate Endpoint (SUR): Blood pressure
Study 31286802 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 19559401 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 19559401 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12967321 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30255188 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22486815 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 18571502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18571502 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8952311 — Predictive Biomarker (PRD): ARX mRNA
Genes: ARX
Study 8952311 — Surrogate Endpoint (SUR): Blood pressure
Study 25252624 — Predictive Biomarker (PRD): Interleukin 4 receptor alpha
Genes: IL4R; IL4RA; 582J2.1
Study 25252624 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16330788 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16330788 — Surrogate Endpoint (SUR): Serum creatinine