TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01998100 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01998100 — Safety Biomarker (SAF): BDNF
Study NCT02819557 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT04668404 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00005472 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02204722 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02204722 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT06304064 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study NCT06304064 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02247167 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04524858 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study NCT04333368 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT04431167 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02777658 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02777658 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04270591 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02330367 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02330367 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00679939 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03292250 — Predictive Biomarker (PRD): ZFP36 mRNA
Genes: ZFP36; G0S24; NUP475; RNF162A; TIS11A; TTP
Study NCT04504071 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03273257 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT03273257 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT03626259 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02952534 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT04075877 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00521287 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00521287 — Predictive Biomarker (PRD): IL7 mRNA
Genes: IL7
Study NCT00521287 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00513383 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00513383 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04165031 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03389230 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03389230 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02767284 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT06724055 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study NCT06724055 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study NCT02960035 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03790722 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02767960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01552603 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study NCT04076280 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04631835 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04996602 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT04045327 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03198559 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01938443 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study NCT00626197 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00864201 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00864201 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04100876 — Predictive Biomarker (PRD): DNMT3A mRNA
Genes: DNMT3A
Study NCT04100876 — Predictive Biomarker (PRD): DNMT3B mRNA
Genes: DNMT3B
Study NCT01156636 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01156636 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03896152 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study NCT01384734 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT02609958 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02609958 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04706494 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01854398 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00652327 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00957879 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT01694849 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02689843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02689843 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT04199559 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study NCT00954551 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT05635435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05635435 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00396019 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT02910284 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03778268 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study NCT00001145 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04197739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04606108 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03452930 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT00473148 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT03618043 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03618043 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00354380 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT06064539 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01283516 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT00659659 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT03583853 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01752296 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study NCT00672334 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT00672334 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00672334 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02527863 — Predictive Biomarker (PRD): AVPR2 mRNA
Genes: AVPR2; ADHR; DIR; DIR3; V2R
Study NCT02598284 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04571450 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00835224 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01664962 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT01664962 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT01932710 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02367547 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study NCT02367547 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study NCT01318395 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01508130 — Predictive Biomarker (PRD): BOC mRNA
Genes: BOC; UNQ604/PRO1190
Study NCT00155779 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01173497 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT02766465 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00669279 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00151281 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02614456 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03670966 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT04974255 — Monitoring Biomarker (MOI): Tissue transglutaminase
Genes: TGM2
Study NCT00064519 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02536027 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT00027170 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03751839 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01923298 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02216656 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT04147689 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00273260 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02252146 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study NCT02283970 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study NCT01455389 — Predictive Biomarker (PRD): TUSC2 mRNA
Genes: TUSC2; C3orf11; FUS1; LGCC; PDAP2
Study NCT02103894 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00336700 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00336700 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04397614 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03555708 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT03166696 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00558922 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3
Study NCT02714790 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT01303406 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT02040740 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02124811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04402905 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT06097351 — Safety Biomarker (SAF): miR-142
Genes: MIR142
Study NCT01841905 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT04315350 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01707836 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT02629653 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT04255680 — Monitoring Biomarker (MOI): Mitochondrial frataxin
Genes: FXN; FRDA; X25
Study NCT00043719 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00518544 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04499118 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT03165227 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00837720 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02911311 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02911311 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02704858 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT04488393 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00136942 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00044265 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00044265 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00490490 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02022904 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00288184 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01724866 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT02420379 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT00911248 — Predictive Biomarker (PRD): NF2 mRNA
Genes: NF2; SCH
Study NCT00911248 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00911248 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03960216 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04606771 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04606771 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04606771 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02416843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04126902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02809547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03233529 — Predictive Biomarker (PRD): KRT16 mRNA
Genes: KRT16; KRT16A
Study NCT03233529 — Predictive Biomarker (PRD): S100A12 mRNA
Genes: S100A12
Study NCT04362956 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00800592 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01062802 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT02892695 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02435121 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01327495 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT04234919 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02393027 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT00569712 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT03976479 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03976479 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03130881 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03693326 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT03693326 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT01180205 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00005368 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04611308 — Predictive Biomarker (PRD): C1QTNF6 mRNA
Genes: C1QTNF6; CTRP6; UNQ581/PRO1151
Study NCT04611308 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04276493 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04276493 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04300556 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT00393783 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04416373 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02766699 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04080453 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study NCT00527566 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT00974324 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00974324 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02895386 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03993600 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT04411160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04179942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04179942 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT04404127 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00195468 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01026532 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03803839 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03291288 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03291288 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01475539 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01625559 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT01276379 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02958631 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03693885 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT03767582 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study NCT03767582 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT03767582 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT01704170 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02944604 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01219348 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT04973787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01544920 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT01363232 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01363232 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study NCT01363232 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01363232 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT01363232 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT01363232 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01840332 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study NCT04168658 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03813316 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT03813316 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01539473 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01994070 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00666822 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01371955 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study NCT02884024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02884024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00998465 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04439227 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04439227 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04439227 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study NCT02289326 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02926833 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03939052 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04870229 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04870229 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04332913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02520063 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02520063 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02136082 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02221882 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02221882 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02221882 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02204501 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00339859 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT03716908 — Predictive Biomarker (PRD): COCH mRNA
Genes: COCH; COCH5B2; UNQ257/PRO294
Study NCT00710177 — Predictive Biomarker (PRD): PTGS1 mRNA
Genes: PTGS1; COX1
Study NCT03377218 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT03377218 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04232917 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03248492 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01524549 — Predictive Biomarker (PRD): CYP2J2 mRNA
Genes: CYP2J2
Study NCT01524549 — Predictive Biomarker (PRD): EPHX2 mRNA
Genes: EPHX2
Study NCT00965666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2