TrialPanorama/TrialPanorama-database huggingface dataset:
Study 29846607 — Predictive Biomarker (PRD): CREB3 mRNA
Genes: CREB3; LZIP
Study 29846607 — Predictive Biomarker (PRD): PRKAR2A mRNA
Genes: PRKAR2A; PKR2; PRKAR2
Study 29846607 — Predictive Biomarker (PRD): PRKCB mRNA
Genes: PRKCB; PKCB; PRKCB1
Study 29846607 — Predictive Biomarker (PRD): PER3 mRNA
Genes: PER3; GIG13
Study 29846607 — Predictive Biomarker (PRD): CAMK2D mRNA
Genes: CAMK2D; CAMKD
Study 29846607 — Predictive Biomarker (PRD): MAPK1 mRNA
Genes: MAPK1; ERK2; PRKM1; PRKM2
Study 28199748 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12663573 — Surrogate Endpoint (SUR): Blood pressure
Study 10704275 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 2423343 — Surrogate Endpoint (SUR): Blood pressure
Study 25896352 — Surrogate Endpoint (SUR): Blood pressure
Study 23720785 — Predictive Biomarker (PRD): DMBX1 mRNA
Genes: DMBX1; MBX; OTX3; PAXB
Study 1614045 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31757218 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20336348 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19246849 — Surrogate Endpoint (SUR): Blood pressure
Study 19246849 — Surrogate Endpoint (SUR): Serum uric acid
Study 19246849 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19246849 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19246849 — Surrogate Endpoint (SUR): Serum triglycerides
Study 16725141 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 2658529 — Surrogate Endpoint (SUR): Blood pressure
Study 9217191 — Predictive Biomarker (PRD): THPO mRNA
Genes: THPO; MGDF
Study 8483855 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8483855 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3038418 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3038418 — Surrogate Endpoint (SUR): Blood pressure
Study 26742700 — Surrogate Endpoint (SUR): Blood pressure
Study 20588105 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16809807 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2905711 — Surrogate Endpoint (SUR): Serum potassium
Study 29398050 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29398050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26139745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26139745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26139745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31640757 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 23832498 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21464401 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 9014018 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 3901391 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11915093 — Surrogate Endpoint (SUR): Blood pressure
Study 23651846 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 23651846 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 17160982 — Surrogate Endpoint (SUR): Blood pressure
Study 11367649 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31995838 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 24674297 — Surrogate Endpoint (SUR): Blood pressure
Study 21987195 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 21987195 — Surrogate Endpoint (SUR): Bone mineral density
Study 9144352 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 2826549 — Surrogate Endpoint (SUR): Blood pressure
Study 25913166 — Surrogate Endpoint (SUR): Blood pressure
Study 20626664 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12648882 — Surrogate Endpoint (SUR): Bone mineral density
Study 12648882 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 10951830 — Surrogate Endpoint (SUR): Blood pressure
Study 31745072 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31745072 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31745072 — Safety Biomarker (SAF): BDNF
Study 8847044 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8847044 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30175557 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 2678309 — Surrogate Endpoint (SUR): Blood pressure
Study 16864756 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11719736 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7787215 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7787215 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 16981473 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 9215828 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30414797 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 10205312 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 3217222 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23745526 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31483964 — Predictive Biomarker (PRD): PKLR mRNA
Genes: PKLR; PK1; PKL
Study 27304428 — Predictive Biomarker (PRD): MMP12 mRNA
Genes: MMP12; HME
Study 27304428 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study 27304428 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CXCL1 mRNA
Genes: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
Study 27304428 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 21734059 — Surrogate Endpoint (SUR): Blood pressure
Study 15609886 — Surrogate Endpoint (SUR): Blood pressure
Study 15609886 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29950456 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27721228 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24781374 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 22732470 — Predictive Biomarker (PRD): SFPQ mRNA
Genes: SFPQ; PSF
Study 1742480 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11531012 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 8029811 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 27333913 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27333913 — Predictive Biomarker (PRD): STAT1 mRNA
Genes: STAT1
Study 27333913 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study 8244516 — Surrogate Endpoint (SUR): Blood pressure
Study 15013305 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 7944706 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 25387655 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11156125 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 29587288 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 29587288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20413121 — Surrogate Endpoint (SUR): Blood pressure
Study 12010586 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 12010586 — Surrogate Endpoint (SUR): Blood pressure
Study 27349705 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26944583 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 26944583 — Safety Biomarker (SAF): Reactive oxygen species
Study 21996058 — Surrogate Endpoint (SUR): Bone mineral density
Study 6089307 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6089307 — Surrogate Endpoint (SUR): Blood pressure
Study 30889043 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23269112 — Surrogate Endpoint (SUR): Blood pressure
Study 15016251 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11150970 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7910838 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16478626 — Predictive Biomarker (PRD): TYMS
Genes: Tsase; TMS; HsT422
Study 12575604 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3684126 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 25483677 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 22743596 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19667251 — Surrogate Endpoint (SUR): Blood pressure
Study 15851259 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12386569 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9537210 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 25997686 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 9783495 — Predictive Biomarker (PRD): GLI2 mRNA
Genes: GLI2; THP
Study 9783495 — Surrogate Endpoint (SUR): Serum creatinine
Study 31219027 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21518554 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study 21518554 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16740113 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 14594020 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12351481 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 24352096 — Safety Biomarker (SAF): Reactive oxygen species
Study 24352096 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1992957 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1992957 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30890061 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22858869 — Predictive Biomarker (PRD): INPP5J mRNA
Genes: INPP5J; PIB5PA; PIPP
Study 20123246 — Surrogate Endpoint (SUR): Blood pressure
Study 9832074 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9832074 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21262066 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21262066 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7903578 — Surrogate Endpoint (SUR): Blood pressure
Study 23963800 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 23823582 — Surrogate Endpoint (SUR): Blood pressure
Study 20223497 — Safety Biomarker (SAF): IL-6 and IL-10
Study 10507423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1748135 — Surrogate Endpoint (SUR): Blood pressure
Study 27670395 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22227852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22227852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22227852 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 22227852 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 22227852 — Safety Biomarker (SAF): IL-6 and IL-10
Study 20929592 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2155739 — Surrogate Endpoint (SUR): Blood pressure
Study 3502447 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 18657652 — Surrogate Endpoint (SUR): Blood pressure
Study 11322152 — Surrogate Endpoint (SUR): Blood pressure
Study 12815801 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9672123 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9672123 — Surrogate Endpoint (SUR): Blood pressure
Study 2547917 — Surrogate Endpoint (SUR): Blood pressure
Study 31221218 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 23467275 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23467275 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 1410142 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25960304 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 25960304 — Predictive Biomarker (PRD): RAPGEF5 mRNA
Genes: RAPGEF5; GFR; KIAA0277; MRGEF
Study 25960304 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25960304 — Surrogate Endpoint (SUR): Serum creatinine
Study 23805859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23805859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23805859 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 23805859 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 21164498 — Surrogate Endpoint (SUR): Blood pressure
Study 21164498 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19027483 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11216491 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11216491 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 15805999 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 9478092 — Safety Biomarker (SAF): Interleukin 1
Study 28821576 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12697884 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 8141126 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 19489872 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19489872 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 19489872 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19489872 — Predictive Biomarker (PRD): LIPC mRNA
Genes: LIPC; HTGL
Study 19489872 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 19489872 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12181401 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 8031206 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8031206 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23492458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23492458 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21211691 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 17852073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17852073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12603352 — Safety Biomarker (SAF): Hyaluronic acid
Study 12603352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12603352 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10837282 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 31005929 — Surrogate Endpoint (SUR): Blood pressure
Study 20384520 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16273791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10320530 — Surrogate Endpoint (SUR): Bone mineral density
Study 8738880 — Safety Biomarker (SAF): PPOX
Genes: HCRT; OX
Study 7049099 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31923099 — Surrogate Endpoint (SUR): Serum calcium
Study 12145026 — Surrogate Endpoint (SUR): Bone mineral density
Study 10103334 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 10103334 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26149841 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 23827100 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15691867 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15691867 — Surrogate Endpoint (SUR): Blood pressure
Study 12162933 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12162933 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 7262184 — Surrogate Endpoint (SUR): Blood pressure
Study 23795312 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23795312 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19854593 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 19854593 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10385761 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8789581 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26105170 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 19250979 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 19250979 — Surrogate Endpoint (SUR): Blood pressure
Study 29396658 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20306535 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7795836 — Surrogate Endpoint (SUR): Blood pressure
Study 30582271 — Surrogate Endpoint (SUR): Blood pressure
Study 27072821 — Predictive Biomarker (PRD): PRCC mRNA
Genes: PRCC; TPRC
Study 27072821 — Predictive Biomarker (PRD): AMACR mRNA
Genes: AMACR
Study 27072821 — Predictive Biomarker (PRD): OSCAR mRNA
Genes: OSCAR
Study 16154016 — Surrogate Endpoint (SUR): Blood pressure
Study 2991817 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26414912 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25363219 — Surrogate Endpoint (SUR): Forced vital capacity
Study 21273036 — Surrogate Endpoint (SUR): Serum creatinine
Study 19148687 — Surrogate Endpoint (SUR): Bone mineral density
Study 30422156 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30422156 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 26200526 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 3061717 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 28089784 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24010577 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 19646778 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16260197 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 10588591 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10588591 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 2179550 — Surrogate Endpoint (SUR): Serum creatinine
Study 21602713 — Surrogate Endpoint (SUR): Blood pressure
Study 15267006 — Surrogate Endpoint (SUR): Serum creatinine
Study 29134614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10961522 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23625945 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10331109 — Surrogate Endpoint (SUR): Blood pressure
Study 8759902 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25384338 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 29580796 — Surrogate Endpoint (SUR): Serum creatinine
Study 26678642 — Surrogate Endpoint (SUR): Blood pressure
Study 18708408 — Safety Biomarker (SAF): MTHFR
Study 10638900 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22239992 — Predictive Biomarker (PRD): IL10RA mRNA
Genes: IL10RA; IL10R
Study 22239992 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 12644982 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7752665 — Surrogate Endpoint (SUR): Blood pressure
Study 29247405 — Surrogate Endpoint (SUR): Blood pressure
Study 16511418 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25675798 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19104452 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11271219 — Surrogate Endpoint (SUR): Serum creatinine
Study 2597714 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19813273 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15569517 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 15569517 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 3926510 — Surrogate Endpoint (SUR): Blood pressure
Study 30035581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28376282 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 25750322 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 23855131 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 28543940 — Surrogate Endpoint (SUR): Bone mineral density
Study 21719441 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19219022 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19219022 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16179085 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16179085 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 28647788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28647788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20514986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1