TrialPanorama/TrialPanorama-database huggingface dataset:
Study 27841912 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24568907 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8562273 — Surrogate Endpoint (SUR): Blood pressure
Study 22118442 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 29754582 — Predictive Biomarker (PRD): MAEA mRNA
Genes: MAEA; EMP; HLC10; PIG5
Study 29754582 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 8935693 — Surrogate Endpoint (SUR): Blood pressure
Study 29678523 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 25065337 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 24721893 — Surrogate Endpoint (SUR): Total kidney volume
Study 15948790 — Surrogate Endpoint (SUR): Blood pressure
Study 12911202 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12911202 — Surrogate Endpoint (SUR): Blood pressure
Study 1925193 — Surrogate Endpoint (SUR): Blood pressure
Study 28027794 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25863661 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27612046 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22872467 — Predictive Biomarker (PRD): NANOS3 mRNA
Genes: NANOS3; NOS3
Study 16008680 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 12747278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12747278 — Surrogate Endpoint (SUR): Bone mineral density
Study 4061119 — Surrogate Endpoint (SUR): Blood pressure
Study 7528908 — Monitoring Biomarker (MOI): HBV DNA
Study 25311256 — Safety Biomarker (SAF): Hyaluronic acid
Study 17009253 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 17009253 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 9077495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3114548 — Surrogate Endpoint (SUR): Blood pressure
Study 24029546 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 20503023 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 28753098 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 25510856 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25510856 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8104070 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8104070 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 3006471 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19363237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19363237 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 19363237 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24705588 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 24705588 — Predictive Biomarker (PRD): ENPP1 mRNA
Genes: ENPP1; M6S1; NPPS; PC1; PDNP1
Study 15840994 — Surrogate Endpoint (SUR): Blood pressure
Study 17161670 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 2888547 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 2847454 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31353479 — Surrogate Endpoint (SUR): Blood pressure
Study 30032171 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28791477 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 26043025 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study 26043025 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26043025 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19104004 — Surrogate Endpoint (SUR): Blood pressure
Study 24152821 — Surrogate Endpoint (SUR): Blood pressure
Study 16673837 — Surrogate Endpoint (SUR): Blood pressure
Study 10865417 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 14710262 — Surrogate Endpoint (SUR): Blood pressure
Study 26606990 — Surrogate Endpoint (SUR): Bone mineral density
Study 9849385 — Surrogate Endpoint (SUR): Bone mineral density
Study 31605208 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31605208 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 27522605 — Surrogate Endpoint (SUR): Blood pressure
Study 25929560 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25929560 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 25929560 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 16079649 — Safety Biomarker (SAF): Cytochrome c
Study 949102 — Surrogate Endpoint (SUR): Blood pressure
Study 25227967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21777013 — Surrogate Endpoint (SUR): Blood pressure
Study 11207321 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26699871 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 14521759 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15642811 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 12146001 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 7768238 — Surrogate Endpoint (SUR): Plasma ammonia
Study 19203712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15131531 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3280484 — Surrogate Endpoint (SUR): Blood pressure
Study 29908345 — Surrogate Endpoint (SUR): Blood pressure
Study 8469785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8469785 — Safety Biomarker (SAF): Urinary microalbumin
Study 30713722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29203893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29203893 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 29203893 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 24067745 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24067745 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23469595 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 20038536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20038536 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 20038536 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20038536 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2536516 — Surrogate Endpoint (SUR): Blood pressure
Study 30944162 — Predictive Biomarker (PRD): CD1C mRNA
Genes: CD1C
Study 30944162 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 30944162 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22099238 — Surrogate Endpoint (SUR): Blood pressure
Study 19440788 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31005993 — Surrogate Endpoint (SUR): Blood pressure
Study 27857631 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 20965712 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 17346628 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2238169 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 8535669 — Safety Biomarker (SAF): 51Cr-EDTA
Study 25867865 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 19548028 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29320587 — Safety Biomarker (SAF): Hyaluronic acid
Study 27097354 — Surrogate Endpoint (SUR): Serum creatinine
Study 15080821 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9249114 — Surrogate Endpoint (SUR): Blood pressure
Study 31703936 — Predictive Biomarker (PRD): CTBS mRNA
Genes: CTBS; CTB
Study 31703936 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 18389900 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11524351 — Surrogate Endpoint (SUR): Blood pressure
Study 8395761 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8395761 — Surrogate Endpoint (SUR): Blood pressure
Study 25461690 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 21298358 — Surrogate Endpoint (SUR): Blood pressure
Study 14610236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14610236 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11391341 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8280188 — Surrogate Endpoint (SUR): Blood pressure
Study 8280188 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9857536 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30659811 — Surrogate Endpoint (SUR): Blood pressure
Study 17076980 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17076980 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17076980 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17076980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9540024 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 7972294 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7972294 — Surrogate Endpoint (SUR): Blood pressure
Study 2585731 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17622942 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 17622942 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 17622942 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 17622942 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 17622942 — Predictive Biomarker (PRD): IL1R1 mRNA
Genes: IL1R1; IL1R; IL1RA; IL1RT1
Study 17622942 — Predictive Biomarker (PRD): IL12RB2 mRNA
Genes: IL12RB2
Study 17622942 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 12095383 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2029180 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 31474119 — Surrogate Endpoint (SUR): Blood pressure
Study 31474119 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22832540 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 19779025 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 8608488 — Predictive Biomarker (PRD): TRO mRNA
Genes: TRO; KIAA1114; MAGED3
Study 31383503 — Surrogate Endpoint (SUR): Blood pressure
Study 31383503 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25887557 — Surrogate Endpoint (SUR): Blood pressure
Study 9888867 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 9888867 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 9888867 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9888867 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 7718754 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7718754 — Surrogate Endpoint (SUR): Blood pressure
Study 22748098 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15906030 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 30536081 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 30239794 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23137494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23137494 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7807658 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7807658 — Surrogate Endpoint (SUR): Blood pressure
Study 7807658 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2947465 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25818388 — Surrogate Endpoint (SUR): Blood pressure
Study 21868617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21868617 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11755325 — Surrogate Endpoint (SUR): Blood pressure
Study 18502107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27471815 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 27471815 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 25816720 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25816720 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 25816720 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19733721 — Surrogate Endpoint (SUR): Blood pressure
Study 15262827 — Predictive Biomarker (PRD): SLC52A2 mRNA
Genes: SLC52A2; GPR172A; PAR1; RFT3
Study 7978091 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28460544 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25441397 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25441397 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 25441397 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 22692637 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 10206309 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study 10829909 — Safety Biomarker (SAF): Beta-N-acetylhexosaminidase
Genes: OGA; HEXC; KIAA0679; MEA5; MGEA5
Study 31222188 — Surrogate Endpoint (SUR): Blood pressure
Study 25066012 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 23363492 — Predictive Biomarker (PRD): SLBP mRNA
Genes: SLBP; HBP
Study 21876296 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 9407447 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27801789 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27801789 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27801789 — Safety Biomarker (SAF): IL-6 and IL-10
Study 23683751 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 23174584 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23174584 — Surrogate Endpoint (SUR): Serum creatinine
Study 23174584 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23132262 — Surrogate Endpoint (SUR): Blood pressure
Study 31451013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 20673141 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20673141 — Surrogate Endpoint (SUR): Blood pressure
Study 23510037 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29193877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23449351 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23449351 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23449351 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22281801 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 30569416 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 25801942 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 19107948 — Predictive Biomarker (PRD): SGTA mRNA
Genes: SGTA; SGT; SGT1
Study 12684305 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 9365968 — Surrogate Endpoint (SUR): Blood pressure
Study 1526090 — Surrogate Endpoint (SUR): Blood pressure
Study 26433318 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 15084178 — Surrogate Endpoint (SUR): Blood pressure
Study 8004831 — Surrogate Endpoint (SUR): Serum creatinine
Study 30225992 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26436207 — Surrogate Endpoint (SUR): Blood pressure
Study 24228894 — Surrogate Endpoint (SUR): Blood pressure
Study 10513866 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26189647 — Predictive Biomarker (PRD): SHC1 mRNA
Genes: SHC1; SHC; SHCA
Study 25014766 — Surrogate Endpoint (SUR): Blood pressure
Study 20594464 — Surrogate Endpoint (SUR): Blood pressure
Study 11818701 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11818701 — Surrogate Endpoint (SUR): Blood pressure
Study 29126212 — Predictive Biomarker (PRD): CYP7B1 mRNA
Genes: CYP7B1
Study 19050053 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 6542243 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25936338 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 9462904 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8778745 — Surrogate Endpoint (SUR): Blood pressure
Study 1104284 — Surrogate Endpoint (SUR): Blood pressure
Study 31266035 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 26265231 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29625605 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16213293 — Surrogate Endpoint (SUR): Serum creatinine
Study 12455359 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7558928 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7558928 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7558928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31464773 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22912941 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22912941 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22912941 — Surrogate Endpoint (SUR): Blood pressure
Study 15573395 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 10430979 — Surrogate Endpoint (SUR): Blood pressure
Study 10430979 — Surrogate Endpoint (SUR): Serum creatinine
Study 10430979 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31371115 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 20585102 — Surrogate Endpoint (SUR): Blood pressure
Study 17369808 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12193097 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9860785 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 4471965 — Surrogate Endpoint (SUR): Blood pressure
Study 11135797 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30912414 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30912414 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 1648142 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 30945320 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 30119145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8961074 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8961074 — Surrogate Endpoint (SUR): Blood pressure
Study 2509064 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26077768 — Surrogate Endpoint (SUR): Blood pressure
Study 21663428 — Surrogate Endpoint (SUR): Blood pressure
Study 11075988 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11075988 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10484572 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8835619 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8835619 — Surrogate Endpoint (SUR): Blood pressure
Study 28054389 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28054389 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 23921777 — Surrogate Endpoint (SUR): Blood pressure
Study 23921777 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21292760 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8034203 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 786673 — Surrogate Endpoint (SUR): Blood pressure
Study 25863779 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 25863779 — Predictive Biomarker (PRD): MMP13 mRNA
Genes: MMP13
Study 25863779 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 23211475 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 23211475 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 23211475 — Surrogate Endpoint (SUR): Bone mineral density
Study 21255472 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15798546 — Surrogate Endpoint (SUR): Blood pressure
Study 1631878 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24614605 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2