TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24612221 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24612221 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17903157 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 31351062 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study 31351062 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 30178600 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 22110589 — Surrogate Endpoint (SUR): Blood pressure
Study 9020538 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 20738062 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 1830108 — Surrogate Endpoint (SUR): Blood pressure
Study 19891698 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8549849 — Surrogate Endpoint (SUR): Blood pressure
Study 30859660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25120022 — Surrogate Endpoint (SUR): Blood pressure
Study 12837854 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 3890140 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24952868 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18315507 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15966876 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7715474 — Surrogate Endpoint (SUR): Bone mineral density
Study 21255780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21255780 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8365423 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26669642 — Surrogate Endpoint (SUR): Serum creatinine
Study 26669642 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 23265585 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 17277734 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 7666085 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 6804113 — Surrogate Endpoint (SUR): Blood pressure
Study 17674759 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 31185917 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25046055 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10024837 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10024837 — Surrogate Endpoint (SUR): Blood pressure
Study 2240002 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16728216 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27921320 — Predictive Biomarker (PRD): MBTPS1 mRNA
Genes: MBTPS1; KIAA0091; S1P; SKI1
Study 25195813 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 23449607 — Surrogate Endpoint (SUR): Blood pressure
Study 15853118 — Surrogate Endpoint (SUR): Blood pressure
Study 10640980 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12601105 — Predictive Biomarker (PRD): GAPDH mRNA
Genes: GAPDH; GAPD; CDABP0047; OK/SW-cl.12
Study 1854617 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 6147940 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24915941 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 10382127 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 1919540 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1919540 — Monitoring Biomarker (MOI): HBV DNA
Study 27196998 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 10980877 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27511452 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 15334379 — Surrogate Endpoint (SUR): Blood pressure
Study 29785872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29785872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29785872 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23175912 — Surrogate Endpoint (SUR): Blood pressure
Study 10344454 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 31024092 — Surrogate Endpoint (SUR): Blood pressure
Study 30830076 — Safety Biomarker (SAF): Hyaluronic acid
Study 25711726 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 25711726 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25711726 — Surrogate Endpoint (SUR): Blood pressure
Study 16442902 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31526206 — Safety Biomarker (SAF): DRD2
Study 27353076 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16794641 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8043291 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 31811010 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 8144779 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 8144779 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 10624454 — Surrogate Endpoint (SUR): Bone mineral density
Study 10624454 — Surrogate Endpoint (SUR): Serum calcium
Study 2172501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21244240 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19591795 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19591795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9551706 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8141156 — Surrogate Endpoint (SUR): Blood pressure
Study 8141156 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8141156 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17055858 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 12743557 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10560780 — Surrogate Endpoint (SUR): Blood pressure
Study 15599837 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27618091 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 1921737 — Surrogate Endpoint (SUR): Serum calcium
Study 1921737 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11701672 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11701672 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26380438 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21934637 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 15545150 — Surrogate Endpoint (SUR): Blood pressure
Study 26176592 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8603262 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8603262 — Safety Biomarker (SAF): Interleukin 1
Study 8603262 — Surrogate Endpoint (SUR): Serum triglycerides
Study 7044649 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7044649 — Predictive Biomarker (PRD): ABCD1 mRNA
Genes: ABCD1; ALD
Study 7044649 — Surrogate Endpoint (SUR): Blood pressure
Study 30452533 — Surrogate Endpoint (SUR): Blood pressure
Study 23913868 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19150064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7869212 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 2531718 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 28472383 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 22821223 — Surrogate Endpoint (SUR): Blood pressure
Study 26613955 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 26613955 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 26613955 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 16914369 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12173784 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 2496993 — Surrogate Endpoint (SUR): Serum creatinine
Study 18637604 — Surrogate Endpoint (SUR): Blood pressure
Study 16767526 — Surrogate Endpoint (SUR): Bone mineral density
Study 3528969 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 12482765 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12482765 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11318005 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 29980595 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29980595 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24947045 — Surrogate Endpoint (SUR): Blood pressure
Study 22104390 — Predictive Biomarker (PRD): MAVS mRNA
Genes: MAVS; IPS1; KIAA1271; VISA
Study 12445035 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 12445035 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7547823 — Surrogate Endpoint (SUR): Bone mineral density
Study 2201403 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 6996139 — Surrogate Endpoint (SUR): Blood pressure
Study 25294299 — Surrogate Endpoint (SUR): Blood pressure
Study 29354933 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 10833331 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 8441234 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 31066232 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 7834398 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6155131 — Surrogate Endpoint (SUR): Blood pressure
Study 18447631 — Surrogate Endpoint (SUR): Blood pressure
Study 9467249 — Predictive Biomarker (PRD): HBA1 mRNA
Genes: HBA1; HBA2
Study 6702613 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6702613 — Surrogate Endpoint (SUR): Blood pressure
Study 30557325 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 21076721 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 21076721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21076721 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 18690806 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12459075 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 1932973 — Surrogate Endpoint (SUR): Blood pressure
Study 1932973 — Surrogate Endpoint (SUR): Serum potassium
Study 1932973 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23697214 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 23697214 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 18157962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16024564 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16024564 — Surrogate Endpoint (SUR): Blood pressure
Study 9708607 — Surrogate Endpoint (SUR): Serum calcium
Study 28122933 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28122933 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 21292088 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 17919488 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17919488 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 17919488 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 17919488 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15490072 — Surrogate Endpoint (SUR): Bone mineral density
Study 11876011 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 29190604 — Surrogate Endpoint (SUR): Serum triglycerides
Study 29190604 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29190604 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24296748 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 8622116 — Surrogate Endpoint (SUR): Serum creatinine
Study 1708060 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1708060 — Surrogate Endpoint (SUR): Blood pressure
Study 30104867 — Surrogate Endpoint (SUR): Blood pressure
Study 8547209 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2025078 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25543854 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17560880 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15191881 — Predictive Biomarker (PRD): OMG mRNA
Genes: OMG; OMGP
Study 12692749 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12692749 — Surrogate Endpoint (SUR): Blood pressure
Study 23700142 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 22489894 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 30681490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23394896 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23394896 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17919270 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29520867 — Surrogate Endpoint (SUR): Blood pressure
Study 28794283 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11213933 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9296310 — Surrogate Endpoint (SUR): Blood pressure
Study 14617243 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16230264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16230264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16230264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17389291 — Surrogate Endpoint (SUR): Bone mineral density
Study 10460042 — Surrogate Endpoint (SUR): Serum testosterone
Study 8546997 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 318984 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 19220493 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17967650 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 10210991 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 26201709 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 15716206 — Safety Biomarker (SAF): Hyaluronic acid
Study 10076773 — Surrogate Endpoint (SUR): Blood pressure
Study 8719069 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 26427109 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 11989524 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31250180 — Predictive Biomarker (PRD): Microsatellite instability
Study 27993911 — Surrogate Endpoint (SUR): Blood pressure
Study 25951636 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 10912743 — Surrogate Endpoint (SUR): Blood pressure
Study 10912743 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9313756 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 9313756 — Predictive Biomarker (PRD): HES1 mRNA
Genes: HES1; BHLHB39; HL; HRY
Study 26739688 — Monitoring Biomarker (MOI): HBV DNA
Study 28673251 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19233181 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 9421103 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 24968251 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24308044 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 22075320 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 22075320 — Surrogate Endpoint (SUR): Blood pressure
Study 19635169 — Predictive Biomarker (PRD): HHIP mRNA
Genes: HHIP; HIP; UNQ5825/PRO19644
Study 15087552 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 8496858 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31628465 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 16039873 — Surrogate Endpoint (SUR): Serum uric acid
Study 14505813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14505813 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8805993 — Surrogate Endpoint (SUR): Bone mineral density
Study 22440854 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 22440854 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 22440854 — Predictive Biomarker (PRD): IL23A mRNA
Genes: IL23A; SGRF; UNQ2498/PRO5798
Study 22440854 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 22440854 — Predictive Biomarker (PRD): OLR1 mRNA
Genes: OLR1; CLEC8A; LOX1
Study 22440854 — Predictive Biomarker (PRD): CXCR1 mRNA
Genes: CXCR1; CMKAR1; IL8RA
Study 22440854 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 22440854 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12714816 — Monitoring Biomarker (MOI): Procalcitonin
Study 12714816 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28624695 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28624695 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study 22198902 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22198902 — Surrogate Endpoint (SUR): Blood pressure
Study 15124080 — Predictive Biomarker (PRD): LOX mRNA
Genes: LOX
Study 8174444 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8174444 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24401221 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14593853 — Surrogate Endpoint (SUR): Blood pressure
Study 25608899 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 12562651 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 28003205 — Surrogate Endpoint (SUR): Blood pressure
Study 10458353 — Surrogate Endpoint (SUR): Blood pressure
Study 28314755 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 24456367 — Surrogate Endpoint (SUR): Blood pressure
Study 17290026 — Surrogate Endpoint (SUR): Serum creatinine
Study 7907668 — Surrogate Endpoint (SUR): Blood pressure
Study 18494750 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10755205 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 31764959 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 28367952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28367952 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22014760 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21451509 — Predictive Biomarker (PRD): CCR1 mRNA
Genes: CCR1; CMKBR1; CMKR1; SCYAR1
Study 21451509 — Monitoring Biomarker (MOI): Macrophage inflammatory protein 1-alpha
Genes: CCL3; G0S19-1; MIP1A; SCYA3
Study 16622646 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 9886157 — Surrogate Endpoint (SUR): Blood pressure
Study 23375931 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 12846896 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 7528126 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 3164788 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3164788 — Surrogate Endpoint (SUR): Blood pressure
Study 30702538 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 11592603 — Monitoring Biomarker (MOI): HBV DNA
Study 7628184 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 2116086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2116086 — Safety Biomarker (SAF): Interleukin 1
Study 28012692 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 23981511 — Predictive Biomarker (PRD): CSAD mRNA
Genes: CSAD; CSD
Study 20137620 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 20137620 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11404230 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31957468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31957468 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31957468 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31477157 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 18727076 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18727076 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 10229720 — Surrogate Endpoint (SUR): Blood pressure
Study 9175240 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 4002804 — Surrogate Endpoint (SUR): Blood pressure
Study 31524143 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29609926 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 11194215 — Surrogate Endpoint (SUR): Blood pressure
Study 11194215 — Surrogate Endpoint (SUR): Serum creatinine
Study 28473063 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28473063 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 28473063 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 28473063 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28473063 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol