TrialPanorama/TrialPanorama-database huggingface dataset:
Study 22231540 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9323645 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22743177 — Monitoring Biomarker (MOI): C-C motif chemokine 4
Genes: CCL4; LAG1; MIP1B; SCYA4
Study 22743177 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25447444 — Surrogate Endpoint (SUR): Serum creatinine
Study 25447444 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 10660149 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 1325831 — Surrogate Endpoint (SUR): Blood pressure
Study 29356827 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22382148 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 22382148 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19462314 — Surrogate Endpoint (SUR): Blood pressure
Study 11226654 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study 23430672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23430672 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23430672 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23430672 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25528311 — Surrogate Endpoint (SUR): Blood pressure
Study 18357530 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26761970 — Surrogate Endpoint (SUR): Blood pressure
Study 8864420 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 6679507 — Surrogate Endpoint (SUR): Blood pressure
Study 15492491 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 20605876 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 20605876 — Surrogate Endpoint (SUR): Blood pressure
Study 11966747 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9863502 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24417563 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 24417563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24417563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18777489 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16454155 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27405968 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 27405968 — Predictive Biomarker (PRD): TFAM mRNA
Genes: TFAM; TCF6; TCF6L2
Study 27405968 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 27405968 — Safety Biomarker (SAF): Reactive oxygen species
Study 18203070 — Surrogate Endpoint (SUR): Blood pressure
Study 15557391 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15557391 — Surrogate Endpoint (SUR): Blood pressure
Study 31394172 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25587059 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 8418273 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26940692 — Surrogate Endpoint (SUR): Serum calcium
Study 12860493 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10527826 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 24960402 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 2963522 — Surrogate Endpoint (SUR): Blood pressure
Study 11743267 — Surrogate Endpoint (SUR): Blood pressure
Study 11743267 — Surrogate Endpoint (SUR): Serum creatinine
Study 28657396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25386830 — Surrogate Endpoint (SUR): Blood pressure
Study 16453248 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 9413749 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 25910632 — Monitoring Biomarker (MOI): Procalcitonin
Study 24192332 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21932025 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 16646033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24530788 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 22550117 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12105117 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11816697 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study 11816697 — Safety Biomarker (SAF): Interleukin 1
Study 17012443 — Surrogate Endpoint (SUR): Blood pressure
Study 11078487 — Predictive Biomarker (PRD): Hormone receptor
Study 1330942 — Surrogate Endpoint (SUR): Blood pressure
Study 24841020 — Surrogate Endpoint (SUR): Blood pressure
Study 23545284 — Surrogate Endpoint (SUR): Pathological complete response
Study 16573311 — Surrogate Endpoint (SUR): Blood pressure
Study 12783039 — Predictive Biomarker (PRD): MYF5 mRNA
Genes: MYF5; BHLHC2
Study 15915396 — Surrogate Endpoint (SUR): Blood pressure
Study 7899535 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28551167 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21656149 — Surrogate Endpoint (SUR): Blood pressure
Study 31254047 — Safety Biomarker (SAF): Hyaluronic acid
Study 11861668 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 11861668 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10417035 — Surrogate Endpoint (SUR): Blood pressure
Study 10417035 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2281392 — Predictive Biomarker (PRD): SIGLEC1 mRNA
Genes: SIGLEC1; SN
Study 31676252 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 17532786 — Monitoring Biomarker (MOI): HBV DNA
Study 10100060 — Surrogate Endpoint (SUR): Blood pressure
Study 1649539 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31852816 — Surrogate Endpoint (SUR): Blood pressure
Study 31091374 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31091374 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31091374 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31091374 — Predictive Biomarker (PRD): Hormone receptor
Study 25737487 — Surrogate Endpoint (SUR): Blood pressure
Study 11273211 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11273211 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 11273211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3779498 — Surrogate Endpoint (SUR): Blood pressure
Study 18301313 — Surrogate Endpoint (SUR): Serum creatinine
Study 22162245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22162245 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 16290961 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16290961 — Surrogate Endpoint (SUR): Serum creatinine
Study 16290961 — Surrogate Endpoint (SUR): Serum potassium
Study 29679637 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28271623 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25681139 — Surrogate Endpoint (SUR): Blood pressure
Study 20508537 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20508537 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23126367 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10919939 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9285143 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19021282 — Surrogate Endpoint (SUR): Serum creatinine
Study 17313873 — Monitoring Biomarker (MOI): HBV DNA
Study 21886949 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17687267 — Surrogate Endpoint (SUR): Blood pressure
Study 14750577 — Predictive Biomarker (PRD): NFIC mRNA
Genes: NFIC; NFI
Study 31121365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31121365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 31121365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31121365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31121365 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31121365 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31121365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27136447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27136447 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 27136447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27136447 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27136447 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27136447 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16485864 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 16485864 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20212249 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 20212249 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18035198 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18035198 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19755476 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 19755476 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18980082 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16184835 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 6846435 — Surrogate Endpoint (SUR): Blood pressure
Study 29560937 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26764419 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 26764419 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 26764419 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 7711149 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 2523656 — Surrogate Endpoint (SUR): Blood pressure
Study 23709457 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9541518 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 9541518 — Surrogate Endpoint (SUR): Bone mineral density
Study 7534716 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7534716 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 2502935 — Surrogate Endpoint (SUR): Blood pressure
Study 25961283 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25961283 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25961283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19022642 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7696598 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 20541301 — Surrogate Endpoint (SUR): Serum creatinine
Study 20541301 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 9395900 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30591656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27574788 — Predictive Biomarker (PRD): CXCR2 mRNA
Genes: CXCR2; IL8RB
Study 28552090 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 10489492 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 1874210 — Surrogate Endpoint (SUR): Blood pressure
Study 24914244 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17457375 — Predictive Biomarker (PRD): NLRP1 mRNA
Genes: NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1
Study 11869770 — Predictive Biomarker (PRD): MSN mRNA
Genes: MSN
Study 28383927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16131513 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 26342706 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 14605041 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 14605041 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 19657359 — Surrogate Endpoint (SUR): Blood pressure
Study 19657359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11560567 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8156520 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 3280114 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 28238606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26890997 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26890997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10451477 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29514368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29514368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28840662 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 22831953 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22831953 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22831953 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22831953 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22831953 — Surrogate Endpoint (SUR): Blood pressure
Study 16776753 — Surrogate Endpoint (SUR): Blood pressure
Study 1532616 — Surrogate Endpoint (SUR): Blood pressure
Study 4029242 — Surrogate Endpoint (SUR): Blood pressure
Study 31415655 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16697307 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 3046816 — Surrogate Endpoint (SUR): Blood pressure
Study 25357214 — Surrogate Endpoint (SUR): Blood pressure
Study 19140039 — Surrogate Endpoint (SUR): Blood pressure
Study 11694150 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 30938127 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 28163108 — Predictive Biomarker (PRD): NR1H3 mRNA
Genes: NR1H3; LXRA
Study 28163108 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 28163108 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 28163108 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 19277420 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 15012646 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12393567 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 29291706 — Surrogate Endpoint (SUR): Blood pressure
Study 24120032 — Surrogate Endpoint (SUR): Serum triglycerides
Study 17716943 — Surrogate Endpoint (SUR): Blood pressure
Study 14530471 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28858981 — Surrogate Endpoint (SUR): Blood pressure
Study 28858981 — Surrogate Endpoint (SUR): Serum creatinine
Study 22613740 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22613740 — Surrogate Endpoint (SUR): Blood pressure
Study 10047626 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7744265 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2116690 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 26202595 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 19626470 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 15593198 — Surrogate Endpoint (SUR): Bone mineral density
Study 9562516 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19406258 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 17388667 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 15457579 — Monitoring Biomarker (MOI): HBV DNA
Study 9547681 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24772585 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20861205 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22285316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22285316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30594892 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30594892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30594892 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25796267 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20346089 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20346089 — Surrogate Endpoint (SUR): Blood pressure
Study 25816544 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 8422744 — Surrogate Endpoint (SUR): Blood pressure
Study 18830037 — Surrogate Endpoint (SUR): Bone mineral density
Study 11875365 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 11875365 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 10359022 — Predictive Biomarker (PRD): LCP1 mRNA
Genes: LCP1; PLS2
Study 10359022 — Predictive Biomarker (PRD): LCP2 mRNA
Genes: LCP2
Study 30646890 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 30646890 — Predictive Biomarker (PRD): CPQ mRNA
Genes: CPQ; LCH1; PGCP
Study 26510464 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 17397061 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 8387912 — Surrogate Endpoint (SUR): Serum calcium
Study 26305570 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 26305570 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 26305570 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24281460 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16541853 — Surrogate Endpoint (SUR): Blood pressure
Study 31124409 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 28156185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 28156185 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 2890021 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31900080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31900080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23782587 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18230277 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10979796 — Surrogate Endpoint (SUR): Bone mineral density
Study 28735463 — Surrogate Endpoint (SUR): Bone mineral density
Study 22153012 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17101639 — Surrogate Endpoint (SUR): Blood pressure
Study 17101639 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16169367 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 16169367 — Surrogate Endpoint (SUR): Blood pressure
Study 31369124 — Surrogate Endpoint (SUR): Blood pressure
Study 29484638 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study 20298323 — Predictive Biomarker (PRD): Small-inducible cytokine A11
Genes: CCL11; SCYA11
Study 1846331 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 7082538 — Surrogate Endpoint (SUR): Serum calcium
Study 22278344 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22278344 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15293895 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30541217 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30541217 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27998236 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 27998236 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22212621 — Surrogate Endpoint (SUR): Blood pressure
Study 24527605 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341