TrialPanorama/TrialPanorama-database huggingface dataset:
Study 23965491 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18487568 — Predictive Biomarker (PRD): FGF7 mRNA
Genes: FGF7; KGF
Study 16947782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16947782 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16947782 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27101297 — Safety Biomarker (SAF): miR-133a
Study 26153084 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 26153084 — Predictive Biomarker (PRD): ANKK1 mRNA
Genes: ANKK1; PKK2; SGK288
Study 26153084 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 3034038 — Surrogate Endpoint (SUR): Blood pressure
Study 26040438 — Surrogate Endpoint (SUR): Blood pressure
Study 11251132 — Surrogate Endpoint (SUR): Blood pressure
Study 30237264 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 19917453 — Predictive Biomarker (PRD): ABCG5 mRNA
Genes: ABCG5
Study 19917453 — Predictive Biomarker (PRD): ABCG8 mRNA
Genes: ABCG8
Study 19917453 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 31363810 — Safety Biomarker (SAF): Hyaluronic acid
Study 21829106 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 16060253 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15023669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15023669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24119521 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 18781288 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 11728983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3319147 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23786174 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 6996627 — Surrogate Endpoint (SUR): Blood pressure
Study 20414043 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22206630 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 12162469 — Surrogate Endpoint (SUR): Blood pressure
Study 29998139 — Surrogate Endpoint (SUR): Blood pressure
Study 19158209 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 15562929 — Surrogate Endpoint (SUR): Serum creatinine
Study 9338047 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9338047 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25974146 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 21374657 — Monitoring Biomarker (MOI): HBV DNA
Study 17175307 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 31791288 — Surrogate Endpoint (SUR): Serum potassium
Study 17050869 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28251755 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19661926 — Surrogate Endpoint (SUR): Blood pressure
Study 27599663 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21311065 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 3355243 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28449657 — Surrogate Endpoint (SUR): Bone mineral density
Study 25646297 — Surrogate Endpoint (SUR): Blood pressure
Study 30782680 — Safety Biomarker (SAF): Hyaluronic acid
Study 8053615 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8053615 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24919692 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 24919692 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FBXO32 mRNA
Genes: FBXO32
Study 10805507 — Surrogate Endpoint (SUR): Blood pressure
Study 8848991 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8848991 — Surrogate Endpoint (SUR): Blood pressure
Study 25959877 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 25959877 — Surrogate Endpoint (SUR): Blood pressure
Study 21617554 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16543910 — Surrogate Endpoint (SUR): Blood pressure
Study 16543910 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15017529 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15017529 — Surrogate Endpoint (SUR): Serum creatinine
Study 15017529 — Surrogate Endpoint (SUR): Blood pressure
Study 15017529 — Surrogate Endpoint (SUR): Serum potassium
Study 30915573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30915573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30915573 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29533303 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 29533303 — Surrogate Endpoint (SUR): Bone mineral density
Study 22404114 — Predictive Biomarker (PRD): IL17RD mRNA
Genes: IL17RD; IL17RLM; SEF; UNQ6115/PRO20026
Study 7793821 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 7793821 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 2354386 — Surrogate Endpoint (SUR): Serum creatinine
Study 29477817 — Surrogate Endpoint (SUR): Serum uric acid
Study 12085250 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12085250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31054484 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 26480546 — Safety Biomarker (SAF): Interleukin 1
Study 26480546 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26480546 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 26480546 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 26480546 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21747013 — Surrogate Endpoint (SUR): Blood pressure
Study 12898306 — Surrogate Endpoint (SUR): Bone mineral density
Study 10193418 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 10193418 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 10193418 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26329790 — Safety Biomarker (SAF): SLCO1B1
Genes: OATP-C; LST-1; OATP1B1
Study 26329790 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26329790 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 23484610 — Surrogate Endpoint (SUR): Blood pressure
Study 19245300 — Surrogate Endpoint (SUR): Blood pressure
Study 19245300 — Surrogate Endpoint (SUR): Serum potassium
Study 24487691 — Surrogate Endpoint (SUR): Bone mineral density
Study 22712469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17823766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22714699 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 22714699 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26070976 — Predictive Biomarker (PRD): PAG1 mRNA
Genes: PAG1; CBP; PAG
Study 23722054 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23722054 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31521831 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12162936 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7051913 — Surrogate Endpoint (SUR): Serum testosterone
Study 7051913 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 31515716 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 24868024 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20015219 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 20015219 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 20015219 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12177267 — Surrogate Endpoint (SUR): Blood pressure
Study 2112080 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 26475266 — Surrogate Endpoint (SUR): Serum creatinine
Study 26475266 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 29737805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29737805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29737805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24429175 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16043735 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 26935044 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 26935044 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 22497849 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17908974 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 31505665 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 19453313 — Surrogate Endpoint (SUR): Blood pressure
Study 7519696 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23171610 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 23171610 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 20187899 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 2220651 — Surrogate Endpoint (SUR): Blood pressure
Study 2220651 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2220651 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2220651 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27624505 — Surrogate Endpoint (SUR): Blood pressure
Study 12225701 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12225701 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9447863 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8523623 — Safety Biomarker (SAF): PPOX
Genes: HCRT; OX
Study 31351492 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21844879 — Surrogate Endpoint (SUR): Blood pressure
Study 17484348 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15115251 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11135718 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 7881705 — Surrogate Endpoint (SUR): Blood pressure
Study 2908300 — Surrogate Endpoint (SUR): Blood pressure
Study 24360050 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24360050 — Surrogate Endpoint (SUR): Blood pressure
Study 14656280 — Surrogate Endpoint (SUR): Serum creatinine
Study 10962520 — Surrogate Endpoint (SUR): Blood pressure
Study 8783393 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27066739 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12657097 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12657097 — Surrogate Endpoint (SUR): Serum testosterone
Study 10723579 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 1541084 — Surrogate Endpoint (SUR): Blood pressure
Study 29534736 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 26882043 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 26882043 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10604482 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10604482 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 20525836 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 12373046 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 12373046 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12373046 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21525141 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 7988077 — Predictive Biomarker (PRD): TNFRSF21 mRNA
Genes: TNFRSF21; DR6; UNQ437/PRO868
Study 8348277 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26496853 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26496853 — Predictive Biomarker (PRD): Microsatellite instability
Study 15914535 — Surrogate Endpoint (SUR): Bone mineral density
Study 8537688 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1907074 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 7051244 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28129130 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 9564459 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 26341595 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23237679 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11578014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11578014 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9692113 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26126940 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 19558398 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 14595084 — Surrogate Endpoint (SUR): Blood pressure
Study 9196111 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8311085 — Surrogate Endpoint (SUR): Serum creatinine
Study 31981567 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 31648099 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 31648099 — Predictive Biomarker (PRD): HRG mRNA
Genes: HRG
Study 28950289 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22796122 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22796122 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21185525 — Surrogate Endpoint (SUR): Blood pressure
Study 9126665 — Surrogate Endpoint (SUR): Serum testosterone
Study 29183782 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12887472 — Surrogate Endpoint (SUR): Serum testosterone
Study 19507458 — Surrogate Endpoint (SUR): Bone mineral density
Study 17418019 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12456630 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 12456630 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 1334126 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 1724541 — Surrogate Endpoint (SUR): Blood pressure
Study 23127169 — Surrogate Endpoint (SUR): Probing pocket depth
Study 2130823 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2130823 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 28648880 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 22474534 — Surrogate Endpoint (SUR): Blood pressure
Study 16104901 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19563641 — Surrogate Endpoint (SUR): Bone mineral density
Study 19563641 — Surrogate Endpoint (SUR): Blood pressure
Study 15241347 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 15241347 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 15241347 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 8183178 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 27895466 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 27895466 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27895466 — Surrogate Endpoint (SUR): Blood pressure
Study 12466334 — Surrogate Endpoint (SUR): Blood pressure
Study 12466334 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12466334 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8991563 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 14503053 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 14503053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 11768164 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 21677054 — Surrogate Endpoint (SUR): Blood pressure
Study 26874076 — Surrogate Endpoint (SUR): Serum creatinine
Study 11407290 — Surrogate Endpoint (SUR): Blood pressure
Study 9297265 — Predictive Biomarker (PRD): AHSP mRNA
Genes: AHSP; EDRF; ERAF
Study 8427863 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19276255 — Predictive Biomarker (PRD): CDKN1B mRNA
Genes: CDKN1B; KIP1; p27
Study 15080782 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 11306209 — Surrogate Endpoint (SUR): Bone mineral density
Study 9704773 — Safety Biomarker (SAF): Hyaluronic acid
Study 9704773 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 16538619 — Surrogate Endpoint (SUR): Bone mineral density
Study 16538619 — Surrogate Endpoint (SUR): Serum calcium
Study 22456295 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22456295 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20089783 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 15853207 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 15853207 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21360075 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11166898 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 1588830 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 12599843 — Surrogate Endpoint (SUR): Blood pressure
Study 11236244 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29261010 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26892582 — Surrogate Endpoint (SUR): Blood pressure
Study 26892582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26892582 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19370271 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 19370271 — Surrogate Endpoint (SUR): Blood pressure
Study 9199483 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1362821 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30297199 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 16093465 — Surrogate Endpoint (SUR): Bone mineral density
Study 11840179 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7214787 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25801871 — Surrogate Endpoint (SUR): Blood pressure
Study 25801871 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25801871 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18378520 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18378520 — Surrogate Endpoint (SUR): Blood pressure
Study 11434703 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 11434703 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11434703 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8311283 — Surrogate Endpoint (SUR): Blood pressure
Study 27154871 — Predictive Biomarker (PRD): BMP2 mRNA
Genes: BMP2; BMP2A
Study 27154871 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 27154871 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27154871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27154871 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27154871 — Surrogate Endpoint (SUR): Bone mineral density
Study 25146720 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 8416081 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 22704229 — Predictive Biomarker (PRD): Tetranectin
Genes: CLEC3B; TNA
Study 25163832 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 22212270 — Surrogate Endpoint (SUR): Blood pressure
Study 8742957 — Surrogate Endpoint (SUR): Serum creatinine
Study 24972577 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 17894656 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 17894656 — Safety Biomarker (SAF): ABCC3
Genes: MRP3; cMOAT2; EST90757; MLP2; MOAT-D
Study 17894656 — Predictive Biomarker (PRD): ABCC4 mRNA
Genes: ABCC4; MOATB; MRP4
Study 21482964 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20382685 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 20382685 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27477476 — Surrogate Endpoint (SUR): Blood pressure
Study 17098749 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 26882111 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 25398799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25398799 — Safety Biomarker (SAF): Interleukin 1
Study 25398799 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 18462811 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12138268 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 11475719 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 2612535 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30592662 — Surrogate Endpoint (SUR): Blood pressure
Study 23942558 — Predictive Biomarker (PRD): HRC mRNA
Genes: HRC; HCP