TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04257656 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02119559 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02119559 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03471143 — Predictive Biomarker (PRD): NPC1 mRNA
Genes: NPC1
Study NCT03471143 — Predictive Biomarker (PRD): NPC2 mRNA
Genes: NPC2; HE1
Study NCT04570124 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00059358 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02510963 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01282372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02862522 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03740724 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study NCT03740724 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study NCT04954560 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT03283774 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03294694 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03294694 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03294694 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03294694 — Predictive Biomarker (PRD): Hormone receptor
Study NCT01334424 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02225119 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study NCT01253642 — Predictive Biomarker (PRD): MAOA mRNA
Genes: MAOA
Study NCT01826474 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01849692 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT04589234 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00218439 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01527760 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03297463 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00783276 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study NCT00542321 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01882543 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study NCT03395977 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03164694 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03164694 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03164694 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT00154934 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT00201903 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT02084563 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study NCT01711164 — Predictive Biomarker (PRD): FGL2 mRNA
Genes: FGL2
Study NCT03565029 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT04411693 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02119429 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01461876 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01461876 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT01461876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04734743 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02988050 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03017820 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT04249622 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02978378 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00938678 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT02133222 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT02133222 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT03753685 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03974386 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT05448040 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FGG mRNA
Genes: FGG; PRO2061
Study NCT03051906 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03051906 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03051906 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT00841217 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT00334464 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00334464 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT04200001 — Predictive Biomarker (PRD): Hormone receptor
Study NCT02858895 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study NCT03831932 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04606225 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02701374 — Pharmacodynamic Biomarker (PDY): Tropomyosin-related kinase A
Genes: NTRK1; MTC; TRK; TRKA
Study NCT04958642 — Predictive Biomarker (PRD): NPC1 mRNA
Genes: NPC1
Study NCT02988115 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01573546 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00381004 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00960453 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01145209 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01035645 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study NCT01648517 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study NCT01648517 — Predictive Biomarker (PRD): Ribonucleoside-diphosphate reductase large subunit
Genes: RRM1; RR1
Study NCT04076787 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01535807 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study NCT03859245 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03859245 — Safety Biomarker (SAF): Cytochrome c
Study NCT04436575 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02472990 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT05635942 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT03952052 — Predictive Biomarker (PRD): MYD88 mRNA
Genes: MYD88
Study NCT02577107 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02577107 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04210167 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04224857 — Predictive Biomarker (PRD): AMT mRNA
Genes: AMT; GCST
Study NCT00897702 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00897702 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02208362 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03892174 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT02971761 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT04814966 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00228358 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02860975 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02925598 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00085462 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00085462 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01056718 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01237041 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT01367639 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01367639 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02548442 — Predictive Biomarker (PRD): CAMP mRNA
Genes: CAMP; CAP18; FALL39; HSD26
Study NCT00516217 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study NCT01768507 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT03896620 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00700778 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00591851 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01862250 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01148160 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03588559 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04180319 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT02019667 — Safety Biomarker (SAF): Succinate-semialdehyde dehydrogenase
Genes: ALDH5A1; SSADH
Study NCT00934635 — Safety Biomarker (SAF): DRD2
Study NCT04385108 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02899455 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04152200 — Predictive Biomarker (PRD): PHC1 mRNA
Genes: PHC1; EDR1; PH1
Study NCT04152200 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT02563314 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03775486 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03775486 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03775486 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04235348 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00659113 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT03868033 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00566423 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study NCT00784940 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01322490 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02103400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02103400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03270280 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study NCT03270280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01277757 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT01277757 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02314481 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT02314481 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02314481 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02314481 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT02874755 — Predictive Biomarker (PRD): PPIA mRNA
Genes: PPIA; CYPA
Study NCT04690140 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT00587158 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02356172 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03788603 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study NCT01256424 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study NCT01256424 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03324243 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01852565 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study NCT01852565 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03150706 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study NCT01763398 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01763398 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01637805 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT00350350 — Predictive Biomarker (PRD): OGT mRNA
Genes: OGT
Study NCT04660136 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04586764 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01956253 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01956253 — Predictive Biomarker (PRD): GRB7 mRNA
Genes: GRB7
Study NCT01097122 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03927339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03927339 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01402453 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03287999 — Predictive Biomarker (PRD): SHB mRNA
Genes: SHB
Study NCT00878956 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00878956 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02438787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00323934 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT00899327 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study NCT04088552 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04027127 — Safety Biomarker (SAF): Netrin-1
Genes: NTN1; NTN1L
Study NCT01773460 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT01773460 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04955457 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04640649 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03315871 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT04217863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04217863 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04217863 — Safety Biomarker (SAF): BDNF
Study NCT04217863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04064034 — Predictive Biomarker (PRD): QSOX1 mRNA
Genes: QSOX1; QSCN6; UNQ2520/PRO6013
Study NCT01658527 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03752684 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT03433963 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00988078 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT02210117 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00022659 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03473691 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT03473691 — Predictive Biomarker (PRD): GDF11 mRNA
Genes: GDF11; BMP11
Study NCT04456816 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04538937 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study NCT05483738 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT05141240 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT01728818 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01728818 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01728818 — Predictive Biomarker (PRD): ERBB4 mRNA
Genes: ERBB4; HER4
Study NCT00251953 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT03640312 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03371017 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01873027 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT03093103 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT01925118 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03943472 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT00920075 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02406586 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02702115 — Predictive Biomarker (PRD): IDUA mRNA
Genes: IDUA
Study NCT03430674 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT03803124 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT03803124 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT02185638 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT00862719 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02643420 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT01928186 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01928186 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01928186 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04223518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04223518 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00574587 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00005707 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04073121 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT00324116 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03878277 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00357331 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01496235 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03525392 — Predictive Biomarker (PRD); Safety Biomarker (SAF): NTSR1 mRNA
Genes: NTSR1; NTRR
Study NCT00088660 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03641690 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT03576807 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT03111836 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01402401 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03393936 — Predictive Biomarker (PRD): AXL mRNA
Genes: AXL; UFO
Study NCT01528345 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01528345 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03698903 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02910050 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02910050 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02910050 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00000526 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study NCT03997461 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00349349 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT02769286 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02769286 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT02769286 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04149405 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Sclerostin
Genes: SOST; UNQ2976/PRO7455/PRO7476
Study NCT01242878 — Predictive Biomarker (PRD): MARCKS mRNA
Genes: MARCKS; MACS; PRKCSL
Study NCT01577459 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02707549 — Surrogate Endpoint (SUR): Serum sodium
Study NCT03909334 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03909334 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00294606 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT04301557 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT00682539 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01664910 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT00854230 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04113317 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04113317 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01291459 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02639832 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT01725490 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT02109965 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT02109965 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT04713254 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT04713254 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT04713254 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02145260 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01262027 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04809597 — Predictive Biomarker (PRD): SNAI2 mRNA
Genes: SNAI2; SLUG; SLUGH
Study NCT04809597 — Predictive Biomarker (PRD): TAL1 mRNA
Genes: TAL1; BHLHA17; SCL; TCL5
Study NCT04041453 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03400228 — Surrogate Endpoint (SUR): Serum creatinine