TrialPanorama/TrialPanorama-database huggingface dataset:
Study 10583422 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1678273 — Surrogate Endpoint (SUR): Blood pressure
Study 17919140 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 16485515 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10534683 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 10534683 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 31126557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31126557 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24998653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24998653 — Surrogate Endpoint (SUR): Blood pressure
Study 22402864 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 2402210 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 25040039 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study 25040039 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 30844623 — Surrogate Endpoint (SUR): Blood pressure
Study 25319731 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30595526 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 27422891 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23169286 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 18042508 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7540397 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15167288 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29626465 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8195908 — Surrogate Endpoint (SUR): Blood pressure
Study 27146272 — Surrogate Endpoint (SUR): Blood pressure
Study 18440179 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15170391 — Surrogate Endpoint (SUR): Blood pressure
Study 28472693 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 17407626 — Surrogate Endpoint (SUR): Blood pressure
Study 12519409 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12519409 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 31537559 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 25349227 — Surrogate Endpoint (SUR): Blood pressure
Study 23138396 — Surrogate Endpoint (SUR): Serum creatinine
Study 23138396 — Surrogate Endpoint (SUR): Blood pressure
Study 21636073 — Surrogate Endpoint (SUR): Blood pressure
Study 16311275 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 10786260 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25721305 — Surrogate Endpoint (SUR): Blood pressure
Study 29071331 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 24895566 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 8730557 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 29381666 — Surrogate Endpoint (SUR): Blood pressure
Study 16043847 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 12417271 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 1776335 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27998015 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 17765963 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17765963 — Surrogate Endpoint (SUR): Blood pressure
Study 30719450 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27641367 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 21865574 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 11843249 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 25343235 — Surrogate Endpoint (SUR): Blood pressure
Study 15145629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15145629 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8445423 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25711324 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23902955 — Surrogate Endpoint (SUR): Serum calcium
Study 28637773 — Surrogate Endpoint (SUR): Bone mineral density
Study 28637773 — Surrogate Endpoint (SUR): Blood pressure
Study 16630748 — Surrogate Endpoint (SUR): Blood pressure
Study 14600520 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6410971 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 27329400 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 26194932 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 11061655 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2877759 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 2877759 — Predictive Biomarker (PRD): GCSAM mRNA
Genes: GCSAM; GAL; GCET2
Study 18937894 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12811613 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 31356921 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 31356921 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 31356921 — Predictive Biomarker (PRD): Interleukin 4 receptor alpha
Genes: IL4R; IL4RA; 582J2.1
Study 31356921 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 31356921 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study 31356921 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 31356921 — Predictive Biomarker (PRD): CCL22 mRNA
Genes: CCL22; MDC; SCYA22; A-152E5.1
Study 31356921 — Predictive Biomarker (PRD): CCL26 mRNA
Genes: CCL26; SCYA26; UNQ216/PRO242
Study 31356921 — Predictive Biomarker (PRD): PI3 mRNA
Genes: PI3; WAP3; WFDC14
Study 31356921 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study 29301124 — Safety Biomarker (SAF): Reactive oxygen species
Study 11219162 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30366505 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 29366667 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 11292931 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22230963 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 20378080 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31238161 — Predictive Biomarker (PRD): LRBA mRNA
Genes: LRBA; BGL; CDC4L; LBA
Study 17560664 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 9855155 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9855155 — Surrogate Endpoint (SUR): Blood pressure
Study 21527660 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21527660 — Surrogate Endpoint (SUR): Serum creatinine
Study 8981141 — Predictive Biomarker (PRD): PALM mRNA
Genes: PALM; KIAA0270
Study 27799756 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11956267 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 11956267 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 11956267 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-C
Genes: HLA-JY3, D6S204, PSORS1
Study 28778185 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 16679259 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 15151263 — Surrogate Endpoint (SUR): Bone mineral density
Study 15151263 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29550238 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 27425415 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 27425415 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 24032554 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 11894976 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study 9592984 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1514709 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31968102 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 31968102 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31968102 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30002437 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30002437 — Predictive Biomarker (PRD): Hormone receptor
Study 30159738 — Safety Biomarker (SAF): Hyaluronic acid
Study 22834767 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22834767 — Surrogate Endpoint (SUR): Blood pressure
Study 21270359 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8827134 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1418778 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26466321 — Surrogate Endpoint (SUR): Blood pressure
Study 630965 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30739259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17925335 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17925335 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17925335 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16669955 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10745280 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10745280 — Surrogate Endpoint (SUR): Blood pressure
Study 31021023 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31021023 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31021023 — Safety Biomarker (SAF): IL-6 and IL-10
Study 28841431 — Surrogate Endpoint (SUR): Blood pressure
Study 16139717 — Surrogate Endpoint (SUR): Bone mineral density
Study 10540009 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 10540009 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 7599728 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31337342 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 16396865 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 27441478 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 21630255 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9734735 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 8295285 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8295285 — Surrogate Endpoint (SUR): Blood pressure
Study 30673020 — Surrogate Endpoint (SUR): Blood pressure
Study 28431534 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28431534 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28431534 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28431534 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21701422 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26983396 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 22614152 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20375709 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17656620 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11824859 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11824859 — Surrogate Endpoint (SUR): Serum sodium
Study 24154560 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 20151251 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 17684044 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10219064 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25559818 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25559818 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 25559818 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31027423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2729124 — Surrogate Endpoint (SUR): Blood pressure
Study 26025699 — Surrogate Endpoint (SUR): Blood pressure
Study 20038724 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20038724 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 20038724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 27129358 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12006958 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7532192 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1646613 — Surrogate Endpoint (SUR): Blood pressure
Study 26404365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17768459 — Surrogate Endpoint (SUR): Blood pressure
Study 10506849 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 2337209 — Surrogate Endpoint (SUR): Blood pressure
Study 19761716 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 19761716 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19761716 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 26313124 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 22926006 — Surrogate Endpoint (SUR): Blood pressure
Study 22926006 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10678268 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10678268 — Surrogate Endpoint (SUR): Blood pressure
Study 17545533 — Predictive Biomarker (PRD): ABCG2 mRNA
Genes: ABCG2; ABCP; BCRP; BCRP1; MXR
Study 8562960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1992393 — Surrogate Endpoint (SUR): Blood pressure
Study 30024999 — Surrogate Endpoint (SUR): Bacterial count
Study 17346705 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 7760093 — Surrogate Endpoint (SUR): Blood pressure
Study 23380426 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 19713172 — Surrogate Endpoint (SUR): Blood pressure
Study 12369047 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 31256724 — Surrogate Endpoint (SUR): Blood pressure
Study 15618549 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 15618549 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 29775547 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29775547 — Surrogate Endpoint (SUR): Blood pressure
Study 21843930 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12386641 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12386641 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23855973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23855973 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 8922766 — Surrogate Endpoint (SUR): Blood pressure
Study 17223409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17223409 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7977316 — Surrogate Endpoint (SUR): Blood pressure
Study 26070913 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 23933953 — Surrogate Endpoint (SUR): Blood pressure
Study 3554564 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 24323178 — Predictive Biomarker (PRD): ESD mRNA
Genes: ESD
Study 20054187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20054187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20054187 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 20054187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20054187 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 8704116 — Surrogate Endpoint (SUR): Serum calcium
Study 31919123 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29078971 — Predictive Biomarker (PRD): CD82 mRNA
Genes: CD82; KAI1; SAR2; ST6; TSPAN27
Study 29078971 — Predictive Biomarker (PRD): ST7 mRNA
Genes: ST7; FAM4A1; HELG; RAY1
Study 26160548 — Predictive Biomarker (PRD): AMY1A mRNA
Genes: AMY1A; AMY1
Study 22325080 — Surrogate Endpoint (SUR): Blood pressure
Study 19672115 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 634895 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 31670238 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 31719124 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 28111430 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 21270194 — Surrogate Endpoint (SUR): Blood pressure
Study 18377903 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25691677 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21199265 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21199265 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19112781 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12973958 — Surrogate Endpoint (SUR): Blood pressure
Study 9403260 — Surrogate Endpoint (SUR): Bacterial count
Study 2844087 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30515164 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 30515164 — Predictive Biomarker (PRD): TLR1 mRNA
Genes: TLR1; KIAA0012
Study 28349708 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20204945 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 18541328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18541328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18541328 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 15818104 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 21910714 — Safety Biomarker (SAF): Interleukin 12
Study 20216207 — Surrogate Endpoint (SUR): Blood pressure
Study 10037308 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 10037308 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10037308 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 3886256 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20482594 — Surrogate Endpoint (SUR): Serum creatinine
Study 10717776 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 10717776 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28129756 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9590631 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14671147 — Surrogate Endpoint (SUR): Serum calcium
Study 22762718 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 12239258 — Surrogate Endpoint (SUR): Serum creatinine
Study 2020314 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25045434 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 22461535 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 19414708 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19414708 — Safety Biomarker (SAF): BDNF
Study 11435719 — Predictive Biomarker (PRD): NRG1 mRNA
Genes: NRG1; GGF; HGL; HRGA; NDF; SMDF
Study 26566148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16856894 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 28369278 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18787510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3532693 — Surrogate Endpoint (SUR): Blood pressure
Study 27646425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27646425 — Surrogate Endpoint (SUR): Serum creatinine
Study 11396390 — Surrogate Endpoint (SUR): Blood pressure
Study 24601137 — Surrogate Endpoint (SUR): Serum creatinine
Study 27060151 — Predictive Biomarker (PRD): PKNOX1 mRNA
Genes: PKNOX1; PREP1
Study 27060151 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 16860051 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 17482880 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26549586 — Surrogate Endpoint (SUR): Serum asparaginase
Study 20733274 — Surrogate Endpoint (SUR): Bone mineral density
Study 16961610 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8851688 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 6369532 — Surrogate Endpoint (SUR): Serum creatinine
Study 18975334 — Surrogate Endpoint (SUR): Bone mineral density
Study 25175842 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25175842 — Surrogate Endpoint (SUR): Blood pressure
Study 23050696 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18300872 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18300872 — Surrogate Endpoint (SUR): Blood pressure
Study 16547085 — Surrogate Endpoint (SUR): Plasma phenylalanine