TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24357473 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24357473 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20955336 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 18173340 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 15985575 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 12486283 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12486283 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 10785284 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10785284 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 10785284 — Surrogate Endpoint (SUR): Blood pressure
Study 30531690 — Surrogate Endpoint (SUR): Blood pressure
Study 30531690 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9438780 — Predictive Biomarker (PRD): PLXNA2 mRNA
Genes: PLXNA2; KIAA0463; OCT; PLXN2; UNQ209/PRO235
Study 29727545 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24143017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24143017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17175376 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 7679737 — Surrogate Endpoint (SUR): Blood pressure
Study 26549803 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22326480 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 6093979 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 12958395 — Predictive Biomarker (PRD): TSN mRNA
Genes: TSN
Study 10945387 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 22355008 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 12805389 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12805389 — Surrogate Endpoint (SUR): Serum testosterone
Study 11591618 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24595224 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28364270 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25887140 — Predictive Biomarker (PRD): NOD2 mRNA
Genes: NOD2; CARD15; IBD1
Study 11716203 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11716203 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 11716203 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 3307635 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 18811802 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 14672354 — Surrogate Endpoint (SUR): Bone mineral density
Study 8603962 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31545671 — Surrogate Endpoint (SUR): Blood pressure
Study 26213242 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 20502695 — Predictive Biomarker (PRD): RND3 mRNA
Genes: RND3; ARHE; RHO8; RHOE
Study 20502695 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 20502695 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 8839230 — Surrogate Endpoint (SUR): Blood pressure
Study 9888411 — Safety Biomarker (SAF): 51Cr-EDTA
Study 9888411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 540461 — Surrogate Endpoint (SUR): Blood pressure
Study 31436371 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 1328367 — Surrogate Endpoint (SUR): Blood pressure
Study 26702863 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20511029 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 12821428 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 12821428 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 10227007 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29440218 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 11772951 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 11772951 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 19968402 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 19968402 — Safety Biomarker (SAF): DRD2
Study 2990189 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 25378675 — Surrogate Endpoint (SUR): Blood pressure
Study 10450748 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31082790 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25946647 — Surrogate Endpoint (SUR): Serum creatinine
Study 23511339 — Surrogate Endpoint (SUR): Blood pressure
Study 20834026 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20834026 — Surrogate Endpoint (SUR): Blood pressure
Study 20834026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20834026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20834026 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11208825 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 21524156 — Surrogate Endpoint (SUR): Serum creatinine
Study 18478022 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study 15339608 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1533588 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1533588 — Surrogate Endpoint (SUR): Blood pressure
Study 1533588 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25732215 — Surrogate Endpoint (SUR): Blood pressure
Study 18441389 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 24417584 — Predictive Biomarker (PRD): RIT1 mRNA
Genes: RIT1; RIBB; RIT; ROC1
Study 20206078 — Predictive Biomarker (PRD): ERCC8 mRNA
Genes: ERCC8; CKN1; CSA
Study 16812979 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11730274 — Safety Biomarker (SAF): 51Cr-EDTA
Study 18774947 — Surrogate Endpoint (SUR): Blood pressure
Study 21429413 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8076659 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1613673 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 15446673 — Surrogate Endpoint (SUR): Blood pressure
Study 9065721 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 7386234 — Surrogate Endpoint (SUR): Blood pressure
Study 28777385 — Safety Biomarker (SAF): Hyaluronic acid
Study 3909759 — Surrogate Endpoint (SUR): Blood pressure
Study 29385062 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 29385062 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29385062 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29385062 — Safety Biomarker (SAF): Interleukin 1
Study 20184866 — Surrogate Endpoint (SUR): Bone mineral density
Study 2405789 — Surrogate Endpoint (SUR): Blood pressure
Study 30467342 — Predictive Biomarker (PRD): CRHR1 mRNA
Genes: CRHR1; CRFR; CRFR1; CRHR
Study 26831124 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26831124 — Surrogate Endpoint (SUR): Blood pressure
Study 22251408 — Surrogate Endpoint (SUR): Serum calcium
Study 22251408 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 22251408 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17951021 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 7986334 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28196533 — Safety Biomarker (SAF): Reactive oxygen species
Study 15131466 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 11237270 — Surrogate Endpoint (SUR): Bone mineral density
Study 27815605 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 25771023 — Surrogate Endpoint (SUR): Blood pressure
Study 9153367 — Predictive Biomarker (PRD): TNFRSF1A
Genes: TNF-R; TNFAR; TNFR60; TNF-R-I; CD120a; TNF-R55
Study 9153367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9153367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29502856 — Predictive Biomarker (PRD): Hormone receptor
Study 28746179 — Predictive Biomarker (PRD): NUBP1 mRNA
Genes: NUBP1; NBP; NBP1
Study 31774112 — Predictive Biomarker (PRD): BTLA mRNA
Genes: BTLA
Study 30414369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30414369 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30414369 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19287288 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 10916570 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 29172605 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 24985779 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1442757 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30626217 — Surrogate Endpoint (SUR): Blood pressure
Study 18076041 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15309442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9223886 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 8267190 — Surrogate Endpoint (SUR): Blood pressure
Study 31097085 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 22884414 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 30520013 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 9797623 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 8592594 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 19185773 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8527549 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 2273082 — Surrogate Endpoint (SUR): Blood pressure
Study 25823535 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 15079108 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 11679441 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 18952561 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30444137 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 2633082 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 29915994 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study 25581584 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 19462697 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 15001200 — Surrogate Endpoint (SUR): Blood pressure
Study 8011800 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 2475681 — Surrogate Endpoint (SUR): Blood pressure
Study 15978968 — Surrogate Endpoint (SUR): Bone mineral density
Study 11840366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11840366 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11840366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9038563 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 26607249 — Surrogate Endpoint (SUR): Blood pressure
Study 12403400 — Surrogate Endpoint (SUR): Blood pressure
Study 10454450 — Surrogate Endpoint (SUR): Blood pressure
Study 21252503 — Surrogate Endpoint (SUR): Blood pressure
Study 16143120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16143120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11865835 — Predictive Biomarker (PRD): PEX19 mRNA
Genes: PEX19; HK33; PXF; OK/SW-cl.22
Study 10206296 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 10206296 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 28918674 — Surrogate Endpoint (SUR): Blood pressure
Study 28918674 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22419733 — Predictive Biomarker (PRD): NPR3 mRNA
Genes: NPR3; ANPRC; C5orf23; NPRC
Study 2147736 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25125679 — Surrogate Endpoint (SUR): Bone mineral density
Study 9605995 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21654269 — Surrogate Endpoint (SUR): Serum uric acid
Study 19781407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7919329 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8570427 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2179650 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 30829734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30829734 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30829734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22238353 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 20846991 — Surrogate Endpoint (SUR): Blood pressure
Study 20846991 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18094424 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 12401583 — Surrogate Endpoint (SUR): Blood pressure
Study 30906300 — Safety Biomarker (SAF): HLA-DRB1
Genes: HLA-DR1B
Study 30906300 — Safety Biomarker (SAF): HLA-DQB1
Genes: IDDM1; CELIAC1
Study 21087222 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17885542 — Surrogate Endpoint (SUR): Blood pressure
Study 12050092 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 29525239 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 23536950 — Surrogate Endpoint (SUR): Blood pressure
Study 23200600 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23200600 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 9374129 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22836068 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22836068 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15958080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15958080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7553993 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7553993 — Surrogate Endpoint (SUR): Blood pressure
Study 1443441 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 31803473 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27087149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27087149 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31812681 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 19158194 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 7986457 — Surrogate Endpoint (SUR): Blood pressure
Study 21491295 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 19657294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19657294 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 17118826 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22440640 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 22440640 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22440640 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1713352 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 19170452 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 11942969 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11942969 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 11942969 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8657505 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 23377899 — Safety Biomarker (SAF): Reactive oxygen species
Study 23377899 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9781629 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19840568 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8620097 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 25643432 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22930403 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 22930403 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8466742 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8466742 — Surrogate Endpoint (SUR): Blood pressure
Study 29930023 — Surrogate Endpoint (SUR): Blood pressure
Study 21068682 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18445178 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18445178 — Surrogate Endpoint (SUR): Blood pressure
Study 22122590 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16172794 — Surrogate Endpoint (SUR): Bone mineral density
Study 16172794 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10587476 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22348388 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 7742579 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2073001 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31287117 — Surrogate Endpoint (SUR): Blood pressure
Study 21389144 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19924586 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 9296731 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30275698 — Surrogate Endpoint (SUR): Blood pressure
Study 30275698 — Surrogate Endpoint (SUR): Serum potassium
Study 22207105 — Predictive Biomarker (PRD); Safety Biomarker (SAF): OPN mRNA
Genes: SPP1; BNSP; OPN; PSEC0156
Study 9038610 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28511023 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 19
Genes: FGF19; UNQ334/PRO533
Study 25529395 — Surrogate Endpoint (SUR): Blood pressure
Study 23072637 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20957430 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8524969 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 2338695 — Surrogate Endpoint (SUR): Blood pressure
Study 23072847 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18787516 — Surrogate Endpoint (SUR): Blood pressure
Study 12407324 — Surrogate Endpoint (SUR): Bone mineral density
Study 22819555 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 22819555 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 22819555 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 9345249 — Predictive Biomarker (PRD): MLXIPL mRNA
Genes: MLXIPL; BHLHD14; MIO; WBSCR14
Study 30515403 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30515403 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30515403 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20855825 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28874133 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 23466656 — Predictive Biomarker (PRD): PRF1
Genes: PFP; P1; HPLH2
Study 11385064 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25861737 — Predictive Biomarker (PRD): PTGDR2 mRNA
Genes: PTGDR2; CRTH2; DL1R; GPR44
Study 23471101 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 15867406 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15867406 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24740547 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8115316 — Surrogate Endpoint (SUR): Blood pressure
Study 21118410 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 26237826 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 23419401 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19666435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19666435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19666435 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 2863295 — Surrogate Endpoint (SUR): Blood pressure
Study 22534255 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22534255 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 20824184 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20824184 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA