TrialPanorama/TrialPanorama-database huggingface dataset:
Study 8203993 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8203993 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3294814 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24823456 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 1888047 — Surrogate Endpoint (SUR): Blood pressure
Study 7158401 — Surrogate Endpoint (SUR): Blood pressure
Study 18338980 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 18338980 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18338980 — Surrogate Endpoint (SUR): Blood pressure
Study 8863008 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 8863008 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 8863008 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1521954 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 29506183 — Surrogate Endpoint (SUR): Blood pressure
Study 29506183 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7652118 — Surrogate Endpoint (SUR): Blood pressure
Study 24968737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24968737 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30550400 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21242856 — Surrogate Endpoint (SUR): Blood pressure
Study 15856433 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 15856433 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27382753 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 17006600 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15609843 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 11726725 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 25966791 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25966791 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 23496322 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 19386307 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 9122731 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 7849443 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26156797 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8245523 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30142768 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 23057533 — Safety Biomarker (SAF): Hyaluronic acid
Study 16837126 — Surrogate Endpoint (SUR): Blood pressure
Study 10906624 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31251550 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 17343554 — Surrogate Endpoint (SUR): Blood pressure
Study 12135309 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12135309 — Surrogate Endpoint (SUR): Blood pressure
Study 19143950 — Surrogate Endpoint (SUR): Blood pressure
Study 18342502 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 15386806 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 12010890 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 31742891 — Surrogate Endpoint (SUR): Blood pressure
Study 29291366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17644552 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 17644552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17644552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17644552 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 8788536 — Surrogate Endpoint (SUR): Blood pressure
Study 25427182 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11829698 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30099096 — Surrogate Endpoint (SUR): Blood pressure
Study 27638636 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 20010118 — Surrogate Endpoint (SUR): Blood pressure
Study 20010118 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16175011 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31262489 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31262489 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 19017277 — Surrogate Endpoint (SUR): Serum creatinine
Study 16960172 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 15554354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25223482 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25223482 — Surrogate Endpoint (SUR): Pathological complete response
Study 21707775 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 9660087 — Predictive Biomarker (PRD): IHH mRNA
Genes: IHH
Study 9660087 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 21450674 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9328113 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 24075505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24075505 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24075505 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24075505 — Surrogate Endpoint (SUR): Blood pressure
Study 21377273 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 8642852 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 16629781 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11028256 — Surrogate Endpoint (SUR): Blood pressure
Study 25896101 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 8117550 — Surrogate Endpoint (SUR): Blood pressure
Study 17934527 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11149501 — Surrogate Endpoint (SUR): Blood pressure
Study 23378299 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23378299 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 16218171 — Monitoring Biomarker (MOI): HBV DNA
Study 9926800 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3283172 — Surrogate Endpoint (SUR): Blood pressure
Study 29731412 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 24202399 — Surrogate Endpoint (SUR): Serum potassium
Study 20693353 — Surrogate Endpoint (SUR): Serum potassium
Study 20693353 — Surrogate Endpoint (SUR): Serum creatinine
Study 10491346 — Surrogate Endpoint (SUR): Blood pressure
Study 7049706 — Surrogate Endpoint (SUR): Blood pressure
Study 26956032 — Surrogate Endpoint (SUR): Blood pressure
Study 26956032 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24368224 — Monitoring Biomarker (MOI): HBV DNA
Study 24368224 — Surrogate Endpoint (SUR): Bone mineral density
Study 22157519 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18000167 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18000167 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15738453 — Surrogate Endpoint (SUR): Blood pressure
Study 8705151 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 8705151 — Surrogate Endpoint (SUR): Blood pressure
Study 10526899 — Surrogate Endpoint (SUR): Blood pressure
Study 7721406 — Surrogate Endpoint (SUR): Blood pressure
Study 7721406 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7721406 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2259927 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22378918 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28697860 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26710337 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 26710337 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study 26710337 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study 21047696 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27702796 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31923729 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17289172 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 7702382 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31881392 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 10679495 — Surrogate Endpoint (SUR): Blood pressure
Study 9301382 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27783027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27783027 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25876341 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 21563952 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 18677972 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 15500103 — Surrogate Endpoint (SUR): Blood pressure
Study 18476954 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12770794 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 16182733 — Surrogate Endpoint (SUR): Serum creatinine
Study 23360656 — Surrogate Endpoint (SUR): Blood pressure
Study 21092293 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 17993594 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 27120082 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 27120082 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 20606661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17256746 — Monitoring Biomarker (MOI): HBV DNA
Study 16297506 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16297506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12235448 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 12235448 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 12235448 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 12235448 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26188786 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 23864647 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19386071 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19386071 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 19386071 — Surrogate Endpoint (SUR): Blood pressure
Study 27684037 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 19565475 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19565475 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19565475 — Surrogate Endpoint (SUR): Serum creatinine
Study 20498618 — Surrogate Endpoint (SUR): Blood pressure
Study 15886236 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15886236 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12598280 — Surrogate Endpoint (SUR): Blood pressure
Study 30475777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30475777 — Monitoring Biomarker (MOI): Procalcitonin
Study 30475777 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30475777 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17999764 — Surrogate Endpoint (SUR): Blood pressure
Study 2692315 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 31004141 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 28581341 — Surrogate Endpoint (SUR): Blood pressure
Study 23495916 — Surrogate Endpoint (SUR): Blood pressure
Study 8091435 — Surrogate Endpoint (SUR): Blood pressure
Study 3053207 — Surrogate Endpoint (SUR): Serum creatinine
Study 22739107 — Predictive Biomarker (PRD): MSTN mRNA
Genes: MSTN; GDF8
Study 12168783 — Safety Biomarker (SAF): Hyaluronic acid
Study 12168783 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 8564096 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8564096 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 8564096 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 23229165 — Surrogate Endpoint (SUR): Blood pressure
Study 2468963 — Surrogate Endpoint (SUR): Blood pressure
Study 16368051 — Surrogate Endpoint (SUR): Blood pressure
Study 16368051 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16368051 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9814501 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 11368483 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11368483 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 11368483 — Predictive Biomarker (PRD): PLXNB1 mRNA
Genes: PLXNB1; KIAA0407; PLXN5; SEP
Study 20379030 — Predictive Biomarker (PRD): SRGN mRNA
Genes: SRGN; PRG; PRG1
Study 16136045 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 16136045 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27115337 — Predictive Biomarker (PRD): CYP2J2 mRNA
Genes: CYP2J2
Study 17616452 — Surrogate Endpoint (SUR): Blood pressure
Study 15812750 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11158473 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 25897569 — Surrogate Endpoint (SUR): Blood pressure
Study 21447945 — Surrogate Endpoint (SUR): Blood pressure
Study 10846514 — Surrogate Endpoint (SUR): Bone mineral density
Study 18078958 — Surrogate Endpoint (SUR): Serum creatinine
Study 2497058 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 14468 — Surrogate Endpoint (SUR): Blood pressure
Study 6163829 — Predictive Biomarker (PRD): DMA mRNA
Genes: DMA; HLA-DMA; hCG_2001572
Study 21737178 — Surrogate Endpoint (SUR): Bacterial count
Study 9718197 — Surrogate Endpoint (SUR): Bone mineral density
Study 8110727 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8110727 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 23146926 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22172779 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19223709 — Surrogate Endpoint (SUR): Blood pressure
Study 15098969 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11676995 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 11676995 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8127531 — Surrogate Endpoint (SUR): Bone mineral density
Study 2758778 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 23083114 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 15530629 — Surrogate Endpoint (SUR): Blood pressure
Study 28620891 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 1568518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26244389 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12783630 — Surrogate Endpoint (SUR): Blood pressure
Study 1312853 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10398549 — Surrogate Endpoint (SUR): Blood pressure
Study 7769811 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7769811 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7769811 — Surrogate Endpoint (SUR): Blood pressure
Study 1905672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30312214 — Surrogate Endpoint (SUR): Blood pressure
Study 24266733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24266733 — Surrogate Endpoint (SUR): Blood pressure
Study 24266733 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23300664 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23300664 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 23300664 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23300664 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15791520 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2215985 — Surrogate Endpoint (SUR): Blood pressure
Study 24659022 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 7835898 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 26138736 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 23391845 — Surrogate Endpoint (SUR): Blood pressure
Study 16475056 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 16475056 — Safety Biomarker (SAF): Reactive oxygen species
Study 16475056 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9166129 — Predictive Biomarker (PRD): ALAD mRNA
Genes: ALAD
Study 25369444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25369444 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26439052 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26439052 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 26439052 — Surrogate Endpoint (SUR): Blood pressure
Study 17074147 — Surrogate Endpoint (SUR): Blood pressure
Study 11588526 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31858865 — Predictive Biomarker (PRD): FANCC
Genes: FAC; FA3
Study 18650223 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28158579 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28158579 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28158579 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 28158579 — Predictive Biomarker (PRD): Hormone receptor
Study 18640378 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 18640378 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18640378 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 12667032 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12667032 — Surrogate Endpoint (SUR): Blood pressure
Study 9101936 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26792391 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8297448 — Surrogate Endpoint (SUR): Serum potassium
Study 3105906 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 30287704 — Surrogate Endpoint (SUR): Blood pressure
Study 28159816 — Surrogate Endpoint (SUR): Blood pressure
Study 24152375 — Surrogate Endpoint (SUR): Blood pressure
Study 24152375 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21918593 — Safety Biomarker (SAF): Urinary total protein
Study 31674641 — Surrogate Endpoint (SUR): Bone mineral density
Study 27003948 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27003948 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 14524580 — Surrogate Endpoint (SUR): Serum creatinine
Study 10739167 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 24892763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18549331 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 28934782 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 22873657 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 20528206 — Predictive Biomarker (PRD): IGFBP4 mRNA
Genes: IGFBP4; IBP4
Study 17761231 — Surrogate Endpoint (SUR): Blood pressure
Study 15801959 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 581636 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31851321 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31851321 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study 31851321 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 31444050 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 31444050 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 25380275 — Surrogate Endpoint (SUR): Blood pressure
Study 25380275 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25380275 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19836774 — Surrogate Endpoint (SUR): Bone mineral density
Study 17097943 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17097943 — Surrogate Endpoint (SUR): Serum creatinine
Study 9351879 — Surrogate Endpoint (SUR): Bone mineral density
Study 26936426 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18540252 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15723890 — Surrogate Endpoint (SUR): Blood pressure
Study 12204500 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 599107 — Surrogate Endpoint (SUR): Blood pressure