TrialPanorama/TrialPanorama-database huggingface dataset:
Study 7788682 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7788682 — Surrogate Endpoint (SUR): Blood pressure
Study 23422155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23422155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9717065 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27469583 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23798345 — Safety Biomarker (SAF): Reactive oxygen species
Study 12445223 — Surrogate Endpoint (SUR): Probing pocket depth
Study 1696669 — Surrogate Endpoint (SUR): Blood pressure
Study 31442599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31442599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15308069 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11217907 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11217907 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11069569 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 22621795 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20554983 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18612042 — Surrogate Endpoint (SUR): Blood pressure
Study 29172992 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22695488 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 27381507 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 19078903 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25426808 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28244291 — Predictive Biomarker (PRD): CR2 mRNA
Genes: CR2; C3DR
Study 24659208 — Surrogate Endpoint (SUR): Serum uric acid
Study 725 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 31238370 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 21835288 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 21835288 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Heart fatty acid-binding protein
Genes: FABP3; FABP11; MDGI
Study 21835288 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19747247 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 16675905 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16675905 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16675905 — Surrogate Endpoint (SUR): Blood pressure
Study 8491393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 8491393 — Safety Biomarker (SAF): 51Cr-EDTA
Study 30350153 — Surrogate Endpoint (SUR): Blood pressure
Study 25380167 — Surrogate Endpoint (SUR): Blood pressure
Study 25380167 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22082432 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 18450322 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 11833826 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11833826 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25205361 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 20658483 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29453769 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21116186 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17167159 — Surrogate Endpoint (SUR): Blood pressure
Study 12585099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10612483 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 10612483 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 10612483 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10612483 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 7742423 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20880870 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 3312501 — Surrogate Endpoint (SUR): Blood pressure
Study 30982743 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30982743 — Surrogate Endpoint (SUR): Serum uric acid
Study 30982743 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25402418 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25029619 — Surrogate Endpoint (SUR): Blood pressure
Study 19478337 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19478337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17225918 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9715861 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 28154006 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23784379 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 20017916 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20017916 — Surrogate Endpoint (SUR): Blood pressure
Study 12488406 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21412846 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 19365587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24956323 — Surrogate Endpoint (SUR): Blood pressure
Study 29275880 — Surrogate Endpoint (SUR): Blood pressure
Study 16990190 — Surrogate Endpoint (SUR): Blood pressure
Study 24389433 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19702079 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 25637294 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 8857071 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8857071 — Surrogate Endpoint (SUR): Blood pressure
Study 1387609 — Surrogate Endpoint (SUR): Blood pressure
Study 2687557 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 2687557 — Surrogate Endpoint (SUR): Blood pressure
Study 30920983 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 24837543 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 16254100 — Predictive Biomarker (PRD): Hormone receptor
Study 16254100 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 7799039 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2405920 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 2405920 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 2405920 — Surrogate Endpoint (SUR): Serum calcium
Study 2405920 — Surrogate Endpoint (SUR): Serum creatinine
Study 15673856 — Surrogate Endpoint (SUR): Blood pressure
Study 2072147 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 19127072 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9674632 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9674632 — Surrogate Endpoint (SUR): Blood pressure
Study 28165562 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 15019315 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 9716581 — Surrogate Endpoint (SUR): Hematologic response
Study 31399910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31399910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31399910 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28393773 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28393773 — Surrogate Endpoint (SUR): Blood pressure
Study 26381921 — Surrogate Endpoint (SUR): Blood pressure
Study 19570388 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9778079 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9778079 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 3154688 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 3154688 — Surrogate Endpoint (SUR): Blood pressure
Study 2822294 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26615516 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31597476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31597476 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29723874 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 26250501 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 1994554 — Surrogate Endpoint (SUR): Blood pressure
Study 26928962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17460714 — Surrogate Endpoint (SUR): Blood pressure
Study 12475452 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7476333 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30395051 — Surrogate Endpoint (SUR): Bone mineral density
Study 28994889 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20131372 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 27440710 — Surrogate Endpoint (SUR): Bone mineral density
Study 23990917 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23990917 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12631367 — Surrogate Endpoint (SUR): Serum creatinine
Study 12631367 — Surrogate Endpoint (SUR): Blood pressure
Study 12631367 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8891805 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28045051 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 23588865 — Surrogate Endpoint (SUR): Blood pressure
Study 9861128 — Predictive Biomarker (PRD): BAG3 mRNA
Genes: BAG3; BIS
Study 354304 — Surrogate Endpoint (SUR): Blood pressure
Study 28985278 — Surrogate Endpoint (SUR): Blood pressure
Study 22348698 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 16398429 — Predictive Biomarker (PRD): TNFRSF10A mRNA
Genes: TNFRSF10A; APO2; DR4; TRAILR1
Study 16398429 — Predictive Biomarker (PRD): TNFRSF10B mRNA
Genes: TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; UNQ160/PRO186
Study 28743315 — Surrogate Endpoint (SUR): Blood pressure
Study 23911260 — Predictive Biomarker (PRD): SLC5A1 mRNA
Genes: SLC5A1; NAGT; SGLT1
Study 23911260 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 23911260 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 2026667 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23959116 — Surrogate Endpoint (SUR): Blood pressure
Study 788002 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 9180166 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29455756 — Surrogate Endpoint (SUR): Blood pressure
Study 25456365 — Surrogate Endpoint (SUR): Bone mineral density
Study 458200 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28830251 — Surrogate Endpoint (SUR): Blood pressure
Study 23966142 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6341724 — Surrogate Endpoint (SUR): Blood pressure
Study 1792613 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 27197690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19382479 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 26358523 — Predictive Biomarker (PRD): Phospholipase A2 inhibitory protein
Genes: ANXA1; ANX1; LPC1
Study 21539525 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study 10550137 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12201967 — Predictive Biomarker (PRD): CDS1 mRNA
Genes: CDS1; CDS
Study 2223274 — Surrogate Endpoint (SUR): Blood pressure
Study 31416011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15064101 — Predictive Biomarker (PRD): TGFA mRNA
Genes: TGFA
Study 9709461 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28964720 — Surrogate Endpoint (SUR): Blood pressure
Study 20493771 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19348656 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9050976 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9050976 — Surrogate Endpoint (SUR): Blood pressure
Study 8319334 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3539617 — Surrogate Endpoint (SUR): Blood pressure
Study 10048638 — Surrogate Endpoint (SUR): Probing pocket depth
Study 28834253 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22945761 — Surrogate Endpoint (SUR): Bone mineral density
Study 19241364 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18201586 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3330986 — Surrogate Endpoint (SUR): Blood pressure
Study 5575973 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17268167 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 9494064 — Safety Biomarker (SAF): Reactive oxygen species
Study 30554193 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study 30554193 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30554193 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26778391 — Surrogate Endpoint (SUR): Probing pocket depth
Study 23479153 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study 8528638 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2305009 — Predictive Biomarker (PRD): MALT1 mRNA
Genes: MALT1; MLT
Study 31003650 — Surrogate Endpoint (SUR): Blood pressure
Study 22466810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 22466810 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 22466810 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 22466810 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22466810 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15908177 — Predictive Biomarker (PRD): FCGR2B
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study 12714861 — Surrogate Endpoint (SUR): Blood pressure
Study 1981017 — Surrogate Endpoint (SUR): Blood pressure
Study 29017395 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 25305053 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 18361314 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 10486669 — Surrogate Endpoint (SUR): Blood pressure
Study 9180976 — Surrogate Endpoint (SUR): Blood pressure
Study 30389581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30389581 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30006474 — Surrogate Endpoint (SUR): Blood pressure
Study 30006474 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30006474 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21047432 — Surrogate Endpoint (SUR): Blood pressure
Study 15578008 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 7985890 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26296850 — Surrogate Endpoint (SUR): Blood pressure
Study 25108751 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 15354209 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15354209 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12398962 — Surrogate Endpoint (SUR): Blood pressure
Study 12398962 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7794581 — Surrogate Endpoint (SUR): Blood pressure
Study 2171046 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 2171046 — Surrogate Endpoint (SUR): Blood pressure
Study 387279 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 23349099 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 14579083 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 18812629 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 1720478 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1720478 — Surrogate Endpoint (SUR): Blood pressure
Study 7326194 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28466419 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 21475971 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 9535249 — Predictive Biomarker (PRD): PRF1
Genes: PFP; P1; HPLH2
Study 9535249 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28230607 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1286524 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 1286524 — Surrogate Endpoint (SUR): Blood pressure
Study 4064569 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27179402 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27179402 — Surrogate Endpoint (SUR): Pathological complete response
Study 19560307 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15610261 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 15610261 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 8582345 — Predictive Biomarker (PRD): F10 mRNA
Genes: F10
Study 15320663 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 8588059 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 14727106 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27026043 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12657843 — Surrogate Endpoint (SUR): Blood pressure
Study 18205099 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18205099 — Surrogate Endpoint (SUR): Serum sodium
Study 12010583 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 9536924 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 8587284 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2571265 — Surrogate Endpoint (SUR): Blood pressure
Study 25616941 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 25616941 — Safety Biomarker (SAF): Hyaluronic acid
Study 23095710 — Surrogate Endpoint (SUR): Blood pressure
Study 19454187 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19454187 — Pharmacodynamic Biomarker (PDY): Interleukin 7 receptor alpha
Genes: IL7R
Study 2669225 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30871361 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2412043 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2412043 — Surrogate Endpoint (SUR): Blood pressure
Study 30536638 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 27378612 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 15618027 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10455471 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 895429 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 895429 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20057195 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 10170452 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8445848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3522422 — Surrogate Endpoint (SUR): Blood pressure
Study 17468494 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21919735 — Surrogate Endpoint (SUR): Blood pressure
Study 6493047 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6493047 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17384176 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 17384176 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 17310221 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 17310221 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17310221 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 17310221 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 11145094 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 1634645 — Surrogate Endpoint (SUR): Blood pressure
Study 23421576 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 17084264 — Surrogate Endpoint (SUR): Blood pressure
Study 17084264 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17084264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15598476 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15598476 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15598476 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30182192 — Surrogate Endpoint (SUR): Blood pressure
Study 23378454 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 23378454 — Safety Biomarker (SAF): Thyroid stimulating hormone