TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30835880 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30835880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 14642140 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 14642140 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 10430112 — Surrogate Endpoint (SUR): Blood pressure
Study 11095468 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 7722967 — Surrogate Endpoint (SUR): Blood pressure
Study 25909710 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25909710 — Predictive Biomarker (PRD): TNFRSF1A mRNA
Genes: TNFRSF1A; TNFAR; TNFR1
Study 25909710 — Predictive Biomarker (PRD): TNFRSF1B mRNA
Genes: TNFRSF1B; TNFBR; TNFR2
Study 24781527 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24781527 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24781527 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study 24781527 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 24781527 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 22366136 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 22366136 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12576241 — Surrogate Endpoint (SUR): Blood pressure
Study 12692572 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12692572 — Surrogate Endpoint (SUR): Serum creatinine
Study 12692572 — Surrogate Endpoint (SUR): Blood pressure
Study 10229991 — Surrogate Endpoint (SUR): Blood pressure
Study 8298199 — Surrogate Endpoint (SUR): Bone mineral density
Study 22985572 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22985572 — Surrogate Endpoint (SUR): Blood pressure
Study 18718422 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 28325697 — Predictive Biomarker (PRD): Activated leukocyte cell adhesionmolecule
Genes: ALCAM; MEMD
Study 28325697 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 26179090 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 9852695 — Surrogate Endpoint (SUR): Blood pressure
Study 25307130 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18804330 — Surrogate Endpoint (SUR): Blood pressure
Study 9190004 — Surrogate Endpoint (SUR): Bone mineral density
Study 25348346 — Safety Biomarker (SAF): BDNF
Study 17631702 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30509850 — Pharmacodynamic Biomarker (PDY): Platelet-derived growth factor B
Genes: PDGFB; PDGF2; SIS
Study 29316154 — Surrogate Endpoint (SUR): Blood pressure
Study 27590259 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 27590259 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23238658 — Surrogate Endpoint (SUR): Blood pressure
Study 21317434 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19966913 — Surrogate Endpoint (SUR): Bone mineral density
Study 23369948 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23369948 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11688002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7955182 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 23204039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23204039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19729522 — Surrogate Endpoint (SUR): Blood pressure
Study 16974199 — Surrogate Endpoint (SUR): Blood pressure
Study 15339684 — Predictive Biomarker (PRD): HBB mRNA
Genes: HBB
Study 15339684 — Predictive Biomarker (PRD): FTL mRNA
Genes: FTL
Study 15339684 — Predictive Biomarker (PRD): ZNF423 mRNA
Genes: ZNF423; KIAA0760; NPHP14; OAZ
Study 31549519 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 21930719 — Surrogate Endpoint (SUR): Blood pressure
Study 21179729 — Predictive Biomarker (PRD): STAT4 mRNA
Genes: STAT4
Study 31724891 — Surrogate Endpoint (SUR): Blood pressure
Study 30131256 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30131256 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20438786 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20438786 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20438786 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 391257 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 23942329 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study 23942329 — Predictive Biomarker (PRD): LMO2 mRNA
Genes: LMO2; RBTN2; RBTNL1; RHOM2; TTG2
Study 25449224 — Surrogate Endpoint (SUR): Blood pressure
Study 23545347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23545347 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23545347 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 23545347 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15265255 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2965159 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2965159 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24232638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24232638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23281842 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 9285181 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9285181 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23003342 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15931642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15931642 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 20802298 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17651830 — Surrogate Endpoint (SUR): Serum creatinine
Study 15774607 — Surrogate Endpoint (SUR): Blood pressure
Study 8748192 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7282519 — Surrogate Endpoint (SUR): Blood pressure
Study 26098004 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 23535987 — Surrogate Endpoint (SUR): Blood pressure
Study 2532458 — Surrogate Endpoint (SUR): Blood pressure
Study 22746542 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6146164 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 29970184 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30835956 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 15681524 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 15681524 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12017317 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12017317 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 3094 — Surrogate Endpoint (SUR): Blood pressure
Study 3094 — Surrogate Endpoint (SUR): Serum uric acid
Study 28403018 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3517076 — Surrogate Endpoint (SUR): Blood pressure
Study 28421628 — Surrogate Endpoint (SUR): Serum creatinine
Study 28421628 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25550228 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 16202394 — Predictive Biomarker (PRD): NOS1AP mRNA
Genes: NOS1AP; CAPON; KIAA0464
Study 10541929 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 21290835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15767642 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25677920 — Surrogate Endpoint (SUR): Serum creatinine
Study 22791802 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 22791802 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 23874575 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21267804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16902841 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 26213156 — Predictive Biomarker (PRD): SLCO2B1 mRNA
Genes: SLCO2B1; KIAA0880; OATP2B1; OATPB; SLC21A9
Study 20546945 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12559781 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 12559781 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 1659189 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30745183 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 30742122 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 23499440 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 16758944 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 16758944 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16758944 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 16758944 — Surrogate Endpoint (SUR): Blood pressure
Study 15089784 — Surrogate Endpoint (SUR): Blood pressure
Study 11274311 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11274311 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11274311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9278199 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 8350363 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15262458 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29951915 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25221948 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28834259 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26291335 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 21188521 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 21188521 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18334913 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 18334913 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Cholinesterase
Genes: BCHE; CHE1
Study 20016927 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 15562907 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 11329798 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 7962672 — Surrogate Endpoint (SUR): Blood pressure
Study 26171380 — Surrogate Endpoint (SUR): Blood pressure
Study 21812891 — Surrogate Endpoint (SUR): Blood pressure
Study 16623961 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 25782319 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23059151 — Predictive Biomarker (PRD): TREH mRNA
Genes: TREH; TREA
Study 17568325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27561823 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 23002126 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18171294 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18171294 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10764713 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 25898404 — Surrogate Endpoint (SUR): Blood pressure
Study 29652273 — Surrogate Endpoint (SUR): Blood pressure
Study 20045196 — Predictive Biomarker (PRD): HTR2C mRNA
Genes: HTR2C; HTR1C
Study 16926775 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10769437 — Surrogate Endpoint (SUR): Serum calcium
Study 10769437 — Surrogate Endpoint (SUR): Bone mineral density
Study 8315266 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22693269 — Surrogate Endpoint (SUR): Blood pressure
Study 1958764 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 20519962 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 20519962 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10435374 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 10435374 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 10435374 — Predictive Biomarker (PRD): TET1 mRNA
Genes: TET1; CXXC6; KIAA1676; LCX
Study 7482625 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7482625 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 6135874 — Surrogate Endpoint (SUR): Serum potassium
Study 27592180 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 20426913 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9590494 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 22175429 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 21046773 — Surrogate Endpoint (SUR): Blood pressure
Study 15891319 — Surrogate Endpoint (SUR): Blood pressure
Study 1989427 — Surrogate Endpoint (SUR): Blood pressure
Study 11349937 — Surrogate Endpoint (SUR): Serum creatinine
Study 9589236 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 15141270 — Surrogate Endpoint (SUR): Blood pressure
Study 12972969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12972969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12972969 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 1829368 — Surrogate Endpoint (SUR): Blood pressure
Study 23682433 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18580415 — Surrogate Endpoint (SUR): Blood pressure
Study 17823083 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17823083 — Surrogate Endpoint (SUR): Bone mineral density
Study 16200917 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16200917 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 27557302 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 29471865 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 27177316 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28779304 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 7928850 — Safety Biomarker (SAF): Reactive oxygen species
Study 28637922 — Predictive Biomarker (PRD): CFI mRNA
Genes: CFI; IF
Study 28637922 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 15758246 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15758246 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 18482144 — Surrogate Endpoint (SUR): Blood pressure
Study 9010373 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8093291 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28741134 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 17284750 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16124970 — Surrogate Endpoint (SUR): Bone mineral density
Study 25885280 — Surrogate Endpoint (SUR): Bone mineral density
Study 19665588 — Surrogate Endpoint (SUR): Blood pressure
Study 19139391 — Surrogate Endpoint (SUR): Blood pressure
Study 16086932 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 282069 — Surrogate Endpoint (SUR): Blood pressure
Study 21562092 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 14711021 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30052729 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 23627026 — Monitoring Biomarker (MOI): HBV DNA
Study 12458653 — Surrogate Endpoint (SUR): Blood pressure
Study 29796934 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 20937186 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1971991 — Surrogate Endpoint (SUR): Blood pressure
Study 375690 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29857165 — Predictive Biomarker (PRD): DDN mRNA
Genes: DDN; KIAA0749
Study 28279168 — Monitoring Biomarker (MOI): HBV DNA
Study 25885732 — Surrogate Endpoint (SUR): Blood pressure
Study 11336164 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11336164 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30581161 — Monitoring Biomarker (MOI): HBV DNA
Study 26160997 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 8624267 — Surrogate Endpoint (SUR): Pathological complete response
Study 23964387 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18928387 — Surrogate Endpoint (SUR): Serum creatinine
Study 9088811 — Surrogate Endpoint (SUR): Blood pressure
Study 3528891 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3528891 — Surrogate Endpoint (SUR): Blood pressure
Study 29737802 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29737802 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27130723 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 15685254 — Surrogate Endpoint (SUR): Serum testosterone
Study 29655971 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19223546 — Predictive Biomarker (PRD): CYP1A1 mRNA
Genes: CYP1A1
Study 19223546 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 19223546 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 19223546 — Predictive Biomarker (PRD): GSTA1 mRNA
Genes: GSTA1
Study 19223546 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 19223546 — Predictive Biomarker (PRD): GSTM3 mRNA
Genes: GSTM3; GST5
Study 19223546 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 19223546 — Predictive Biomarker (PRD): SULT1A1 mRNA
Genes: SULT1A1; STP; STP1; OK/SW-cl.88
Study 19223546 — Predictive Biomarker (PRD): SULT1A2 mRNA
Genes: SULT1A2; STP2
Study 21511219 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 8309562 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study 2468912 — Surrogate Endpoint (SUR): Blood pressure
Study 25898343 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 20939913 — Surrogate Endpoint (SUR): Blood pressure
Study 20939913 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6148312 — Surrogate Endpoint (SUR): Blood pressure
Study 27644138 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9247510 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27840374 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10853566 — Surrogate Endpoint (SUR): Blood pressure
Study 2312774 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 2312774 — Surrogate Endpoint (SUR): Serum triglycerides
Study 22534669 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12952837 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 2073484 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 6366148 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 10025472 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27623133 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 21903893 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 25683748 — Surrogate Endpoint (SUR): Blood pressure
Study 23808298 — Surrogate Endpoint (SUR): Blood pressure
Study 12963561 — Surrogate Endpoint (SUR): Blood pressure
Study 30892820 — Surrogate Endpoint (SUR): Blood pressure
Study 30892820 — Surrogate Endpoint (SUR): Serum uric acid
Study 27117038 — Surrogate Endpoint (SUR): Serum creatinine
Study 23525418 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 12851527 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2830968 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31937915 — Surrogate Endpoint (SUR): Blood pressure
Study 28277432 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28277432 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21744744 — Surrogate Endpoint (SUR): Serum testosterone
Study 30123970 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 30123970 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30123970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30123970 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30123970 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 1352828 — Surrogate Endpoint (SUR): Blood pressure
Study 6371693 — Surrogate Endpoint (SUR): Blood pressure
Study 30021759 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 24577847 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 28595236 — Safety Biomarker (SAF): IL-6 and IL-10
Study 25217488 — Predictive Biomarker (PRD): MPG mRNA
Genes: MPG; AAG; ANPG; MID1
Study 1636917 — Surrogate Endpoint (SUR): Blood pressure