TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02309983 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03119922 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03050307 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT02812615 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT02812615 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01306604 — Predictive Biomarker (PRD): NPC1 mRNA
Genes: NPC1
Study NCT01306604 — Predictive Biomarker (PRD): NPC2 mRNA
Genes: NPC2; HE1
Study NCT03613168 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT05427864 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT00249912 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01877291 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT02322255 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT02936362 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02461849 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT04728009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01877005 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study NCT01877005 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT02467660 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01775800 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02388672 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT02388672 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01362972 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02279160 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02279160 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01525108 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01606774 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00472043 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02352090 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02602704 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02663115 — Predictive Biomarker (PRD): CALD1 mRNA
Genes: CALD1; CAD; CDM
Study NCT05764811 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT05764811 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study NCT02142972 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT00224497 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study NCT00464620 — Predictive Biomarker (PRD): SRC mRNA
Genes: SRC; SRC1
Study NCT03716856 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03860844 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT03028532 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT04324021 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT04324021 — Safety Biomarker (SAF): Interleukin 1
Study NCT02253147 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00486525 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02497053 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01023646 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01023646 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00003056 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00098605 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00444587 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02072733 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study NCT06343129 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00916643 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00169585 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study NCT03371589 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03364062 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02591836 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02591836 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02591836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02591836 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00572312 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00572312 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01296178 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01296178 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study NCT00317603 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00825734 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02535689 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02771769 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02541968 — Predictive Biomarker (PRD): PSMB6 mRNA
Genes: PSMB6; LMPY; Y
Study NCT01769456 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01769456 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02788617 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03334773 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00625677 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study NCT03640416 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01718015 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT01718015 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01718015 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT01718015 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01580007 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT04331015 — Predictive Biomarker (PRD): COCH mRNA
Genes: COCH; COCH5B2; UNQ257/PRO294
Study NCT02411773 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01864304 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01513278 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study NCT04753762 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00805974 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02651376 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03697824 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT03137056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03137056 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01723514 — Pharmacodynamic Biomarker (PDY): Dermal blood flow
Study NCT04685369 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01094548 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT00919009 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00919009 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01829685 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00502983 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study NCT00502983 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study NCT00502983 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study NCT00502983 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study NCT00502983 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT00481546 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT01666990 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01666990 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT01666990 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03521401 — Safety Biomarker (SAF): BDNF
Study NCT02456571 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT00409396 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02108522 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01160224 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CCR3 mRNA
Genes: CCR3; CMKBR3
Study NCT01253941 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01253941 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03838601 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02921906 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study NCT01245127 — Safety Biomarker (SAF): Interleukin 1
Study NCT01037140 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03813199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01380600 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04093466 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT04093466 — Predictive Biomarker (PRD): MET
Genes: HGFR; RCCP2; DFNB97
Study NCT04093466 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04093466 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04093466 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT02022891 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT00051103 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04087798 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04087798 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00085644 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00486889 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT03938909 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study NCT03310749 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03310749 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00002780 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04931121 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00948714 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03792893 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04501978 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01739049 — Predictive Biomarker (PRD): NPY mRNA
Genes: NPY
Study NCT01739049 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT03467997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT05122052 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT05122052 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT00590941 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT03592927 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT06507215 — Predictive Biomarker (PRD): DYSF mRNA
Genes: DYSF; FER1L1
Study NCT00033462 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00497198 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT01879085 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT02778425 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04412668 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01554605 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00150956 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01810289 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04231747 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03721978 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT01521689 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01609491 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01928407 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01319227 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00912496 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02186015 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02810483 — Surrogate Endpoint (SUR): Plasma ammonia
Study NCT00004016 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03052283 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT01362283 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01475019 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01862185 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT01632202 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT03694119 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02183350 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02949622 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03736499 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study NCT03736499 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT02649660 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT03703141 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT01518673 — Pharmacodynamic Biomarker (PDY): Gamma-Histone H2AX
Genes: H2AX; H2AFX
Study NCT02325089 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01376505 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00359385 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01439256 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03426189 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03739333 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT04659200 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study NCT04659200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04659200 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04659200 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT01705223 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04045522 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04138043 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study NCT01892124 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02893085 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02893085 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02893085 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02893085 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT02893085 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT02893085 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02893085 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02893085 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study NCT02893085 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT02893085 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT02893085 — Predictive Biomarker (PRD): TGFBR1 mRNA
Genes: TGFBR1; ALK5; SKR4
Study NCT02893085 — Predictive Biomarker (PRD): TGFBR2 mRNA
Genes: TGFBR2
Study NCT02893085 — Predictive Biomarker (PRD): ARID1B mRNA
Genes: ARID1B; BAF250B; DAN15; KIAA1235; OSA2
Study NCT02893085 — Predictive Biomarker (PRD): GNAS mRNA
Genes: GNAS; GNAS1
Study NCT02893085 — Predictive Biomarker (PRD): RNF43 mRNA
Genes: RNF43
Study NCT02893085 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02893085 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01079728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01079728 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT01122186 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03765151 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT03590938 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01961921 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT05143879 — Predictive Biomarker (PRD): CIT mRNA
Genes: CIT; CRIK; KIAA0949; STK21
Study NCT05143879 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT03182777 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04358068 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00979745 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01678898 — Predictive Biomarker (PRD): PRX mRNA
Genes: PRX; KIAA1620
Study NCT01678898 — Predictive Biomarker (PRD): GLA
Genes: GALA
Study NCT00352391 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study NCT01729611 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01729611 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01408043 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04351360 — Predictive Biomarker (PRD): ADCY5 mRNA
Genes: ADCY5
Study NCT00958555 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00958555 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02884804 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT04341324 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04341324 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03514290 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT03066258 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03066258 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01480245 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT03172195 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02580214 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01329172 — Predictive Biomarker (PRD): MUC5B mRNA
Genes: MUC5B; MUC5
Study NCT01329172 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT01329172 — Predictive Biomarker (PRD): MUC2 mRNA
Genes: MUC2; SMUC
Study NCT01329172 — Predictive Biomarker (PRD): MUC4 mRNA
Genes: MUC4
Study NCT01329172 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study NCT01329172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02514369 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT02514369 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study NCT02514369 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT02514369 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT02514369 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01081730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04566055 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04467294 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02502240 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02502240 — Predictive Biomarker (PRD): EML4 mRNA
Genes: EML4; C2orf2; EMAPL4
Study NCT00492518 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT01130714 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02494453 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04756115 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT04756115 — Safety Biomarker (SAF): Platelet to lymphocyte
Study NCT02644915 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04659369 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03888261 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04303871 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03529084 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03793140 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT03793140 — Predictive Biomarker (PRD): Apoptosis regulator Bcl-2
Genes: BCL2
Study NCT03793140 — Predictive Biomarker (PRD): BCL6 mRNA
Genes: BCL6; BCL5; LAZ3; ZBTB27; ZNF51
Study NCT03839537 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT04402385 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05326906 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT01363297 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study NCT04170556 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT04170556 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51