TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25214041 — Predictive Biomarker (PRD): CEBPA mRNA
Genes: CEBPA; CEBP
Study 22898992 — Surrogate Endpoint (SUR): Blood pressure
Study 2686455 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2686455 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24356798 — Predictive Biomarker (PRD): Hormone receptor
Study 29683919 — Surrogate Endpoint (SUR): Blood pressure
Study 21467697 — Surrogate Endpoint (SUR): Serum creatinine
Study 19525846 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 8712429 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 1888641 — Surrogate Endpoint (SUR): Blood pressure
Study 31327131 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28724799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19896079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15370080 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 10840082 — Surrogate Endpoint (SUR): Blood pressure
Study 9338926 — Surrogate Endpoint (SUR): Bone mineral density
Study 9338926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30642528 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 8681162 — Surrogate Endpoint (SUR): Blood pressure
Study 28948296 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 3916511 — Surrogate Endpoint (SUR): Serum creatinine
Study 31752938 — Surrogate Endpoint (SUR): Blood pressure
Study 25593907 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20562693 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18557810 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12066724 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26709542 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26709542 — Surrogate Endpoint (SUR): Blood pressure
Study 25480994 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25480994 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 25480994 — Safety Biomarker (SAF): Interleukin 1
Study 18087554 — Surrogate Endpoint (SUR): Blood pressure
Study 28625245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28625245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26028962 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 15545203 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 27353719 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 21058480 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 7674293 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31129183 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15125719 — Surrogate Endpoint (SUR): Blood pressure
Study 28840583 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25573908 — Predictive Biomarker (PRD): APOL1 mRNA
Genes: APOL1; APOL
Study 16192502 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9118847 — Surrogate Endpoint (SUR): Serum creatinine
Study 29672897 — Predictive Biomarker (PRD): JAK1
Genes: JAK1A; JTK3
Study 15752945 — Surrogate Endpoint (SUR): Blood pressure
Study 29277856 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 29277856 — Safety Biomarker (SAF): Hyaluronic acid
Study 21742098 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 15001605 — Surrogate Endpoint (SUR): Serum testosterone
Study 11709513 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 11709513 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2885116 — Surrogate Endpoint (SUR): Blood pressure
Study 30824268 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30824268 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12148574 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2454514 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2454514 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 2454514 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 25082954 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 25082954 — Surrogate Endpoint (SUR): Blood pressure
Study 14965840 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 8223829 — Surrogate Endpoint (SUR): Blood pressure
Study 8594515 — Surrogate Endpoint (SUR): Blood pressure
Study 2015119 — Surrogate Endpoint (SUR): Blood pressure
Study 29850782 — Surrogate Endpoint (SUR): Blood pressure
Study 16644783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11445622 — Surrogate Endpoint (SUR): Blood pressure
Study 8061995 — Surrogate Endpoint (SUR): Bone mineral density
Study 16292207 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16292207 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 16292207 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 16292207 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29275919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29275919 — Surrogate Endpoint (SUR): Blood pressure
Study 20007932 — Surrogate Endpoint (SUR): Blood pressure
Study 10527181 — Surrogate Endpoint (SUR): Bone mineral density
Study 7669481 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7669481 — Surrogate Endpoint (SUR): Blood pressure
Study 7669481 — Surrogate Endpoint (SUR): Serum uric acid
Study 7669481 — Surrogate Endpoint (SUR): Serum creatinine
Study 7669481 — Surrogate Endpoint (SUR): Serum potassium
Study 31531960 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25502511 — Surrogate Endpoint (SUR): Serum creatinine
Study 19954719 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19954719 — Surrogate Endpoint (SUR): Serum creatinine
Study 17578464 — Surrogate Endpoint (SUR): Blood pressure
Study 15187493 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15187493 — Surrogate Endpoint (SUR): Blood pressure
Study 27687355 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 21056810 — Surrogate Endpoint (SUR): Blood pressure
Study 9534963 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31229240 — Predictive Biomarker (PRD): CSF1 mRNA
Genes: CSF1
Study 21971662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21971662 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11597824 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 22104547 — Surrogate Endpoint (SUR): Blood pressure
Study 31813058 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16531899 — Surrogate Endpoint (SUR): Blood pressure
Study 8466715 — Surrogate Endpoint (SUR): Blood pressure
Study 21616975 — Safety Biomarker (SAF): DRD2
Study 10890026 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10890026 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9100582 — Surrogate Endpoint (SUR): Bone mineral density
Study 20863951 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20863951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15944845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12883404 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30325018 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 30325018 — Predictive Biomarker (PRD): TBC1D4 mRNA
Genes: TBC1D4; AS160; KIAA0603
Study 22971356 — Surrogate Endpoint (SUR): Blood pressure
Study 14643816 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19194995 — Predictive Biomarker (PRD): ENPP2 mRNA
Genes: ENPP2; ATX; PDNP2
Study 29433850 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29433850 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29433850 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 24875610 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24875610 — Predictive Biomarker (PRD): GLS2 mRNA
Genes: GLS2; GA
Study 24875610 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17919718 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 2143459 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2143459 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2143459 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11549632 — Surrogate Endpoint (SUR): Bone mineral density
Study 7509244 — Predictive Biomarker (PRD): DDR1 mRNA
Genes: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Study 7509244 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21958782 — Predictive Biomarker (PRD): BAX mRNA
Genes: BAX; BCL2L4
Study 21958782 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 18328363 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22762844 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20164395 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 18058736 — Predictive Biomarker (PRD): Hormone receptor
Study 17617280 — Surrogate Endpoint (SUR): Blood pressure
Study 14707154 — Surrogate Endpoint (SUR): Blood pressure
Study 25924880 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 19304119 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17805035 — Surrogate Endpoint (SUR): Bone mineral density
Study 15657405 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 11959402 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8815124 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21809148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16882622 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 9042095 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9042095 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31695136 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 28474088 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24730717 — Safety Biomarker (SAF): BDNF
Study 26999011 — Predictive Biomarker (PRD): EBF1 mRNA
Genes: EBF1; COE1; EBF
Study 24786356 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 24786356 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24786356 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12594633 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 11783334 — Predictive Biomarker (PRD): GRN mRNA
Genes: GRN
Study 20430458 — Surrogate Endpoint (SUR): Pathological complete response
Study 388400 — Surrogate Endpoint (SUR): Serum uric acid
Study 388400 — Surrogate Endpoint (SUR): Serum creatinine
Study 22409922 — Predictive Biomarker (PRD): CD63 mRNA
Genes: CD63; MLA1; TSPAN30
Study 8695129 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8695129 — Surrogate Endpoint (SUR): Blood pressure
Study 12185449 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12185449 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 1725543 — Surrogate Endpoint (SUR): Blood pressure
Study 23475701 — Surrogate Endpoint (SUR): Blood pressure
Study 23258574 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 18060746 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11322256 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6809420 — Surrogate Endpoint (SUR): Blood pressure
Study 24165361 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 19700435 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19700435 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 19700435 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 8557061 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 26242287 — Predictive Biomarker (PRD): KCNN3 mRNA
Genes: KCNN3; K3
Study 18173921 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18173921 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30946262 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19592223 — Surrogate Endpoint (SUR): Blood pressure
Study 17479256 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 11526473 — Predictive Biomarker (PRD): TPH1 mRNA
Genes: TPH1; TPH; TPRH; TRPH
Study 2015168 — Surrogate Endpoint (SUR): Blood pressure
Study 30639574 — Surrogate Endpoint (SUR): Blood pressure
Study 28490464 — Predictive Biomarker (PRD): EGR3 mRNA
Genes: EGR3; PILOT
Study 28490464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28490464 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26264470 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17573988 — Surrogate Endpoint (SUR): Blood pressure
Study 15164437 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9451748 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15374271 — Surrogate Endpoint (SUR): Bone mineral density
Study 2828820 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 24244295 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 20378921 — Surrogate Endpoint (SUR): Blood pressure
Study 17213004 — Surrogate Endpoint (SUR): Blood pressure
Study 10958764 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 10958764 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23635681 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23635681 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9741509 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28570317 — Surrogate Endpoint (SUR): Blood pressure
Study 25928457 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 25928457 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23849306 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 8349379 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 18002724 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 18002724 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 26994230 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15844838 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 10579275 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26259617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11566640 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 9624696 — Predictive Biomarker (PRD): CLC mRNA
Genes: CLC; LGALS10; LGALS10A
Study 24828094 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24828094 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23174063 — Surrogate Endpoint (SUR): Bone mineral density
Study 18614402 — Surrogate Endpoint (SUR): Blood pressure
Study 12614526 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10651119 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31578564 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17991651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17991651 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30544335 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 30544335 — Predictive Biomarker (PRD): IL13
Genes: P600; IL-13; ALRH; BHR1; MGC116786; MGC116788; MGC116789
Study 25022834 — Surrogate Endpoint (SUR): Blood pressure
Study 18702964 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18574557 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 18574557 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9309995 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24700403 — Surrogate Endpoint (SUR): Blood pressure
Study 15584487 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 15584487 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 26171933 — Predictive Biomarker (PRD): Hormone receptor
Study 26171933 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 10508227 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26031737 — Surrogate Endpoint (SUR): Blood pressure
Study 15389235 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11177086 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31313942 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28341525 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 19563648 — Surrogate Endpoint (SUR): Serum creatinine
Study 24576513 — Surrogate Endpoint (SUR): Blood pressure
Study 22321661 — Surrogate Endpoint (SUR): Bone mineral density
Study 17923611 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 6106884 — Surrogate Endpoint (SUR): Blood pressure
Study 6106884 — Surrogate Endpoint (SUR): Serum potassium
Study 6106884 — Surrogate Endpoint (SUR): Serum uric acid
Study 2556725 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2556725 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 31175001 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 15494230 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 11341354 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11341354 — Safety Biomarker (SAF): Interleukin 12
Study 9004097 — Surrogate Endpoint (SUR): Blood pressure
Study 28605730 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 22996370 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25887358 — Surrogate Endpoint (SUR): Blood pressure
Study 15499697 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3307795 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27401564 — Surrogate Endpoint (SUR): Serum creatinine
Study 21610201 — Predictive Biomarker (PRD): FFAR1 mRNA
Genes: FFAR1; GPR40
Study 17980667 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12483717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12483717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26685869 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26685869 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26685869 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26685869 — Surrogate Endpoint (SUR): Blood pressure
Study 22495174 — Predictive Biomarker (PRD): DRD1 mRNA
Genes: DRD1
Study 26856247 — Surrogate Endpoint (SUR): Bone mineral density
Study 8006397 — Monitoring Biomarker (MOI): HBV DNA
Study 29241576 — Surrogate Endpoint (SUR): Blood pressure
Study 16214329 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16214329 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 16214329 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11425671 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 18998824 — Surrogate Endpoint (SUR): Blood pressure
Study 12514663 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12514663 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1338083 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1338083 — Surrogate Endpoint (SUR): Blood pressure
Study 2580171 — Surrogate Endpoint (SUR): Blood pressure
Study 18519835 — Surrogate Endpoint (SUR): Forced vital capacity
Study 12915670 — Surrogate Endpoint (SUR): Bone mineral density