TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20500100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20500100 — Surrogate Endpoint (SUR): Bone mineral density
Study 20500100 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 17825587 — Safety Biomarker (SAF): Interleukin 1
Study 16815486 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30217374 — Predictive Biomarker (PRD): BLK mRNA
Genes: BLK
Study 24894410 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 20625111 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15793606 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22674146 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 16214025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31880343 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 18716688 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15314393 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 8287567 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 8287567 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 2882294 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24079037 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20076856 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 20076856 — Predictive Biomarker (PRD): TOB1 mRNA
Genes: TOB1; TOB; TROB1
Study 18194028 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 16387583 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 15057400 — Surrogate Endpoint (SUR): Blood pressure
Study 24669750 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16294264 — Surrogate Endpoint (SUR): Serum creatinine
Study 12412806 — Surrogate Endpoint (SUR): Bone mineral density
Study 21689142 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 12742999 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 24133627 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 21367625 — Surrogate Endpoint (SUR): Blood pressure
Study 21367625 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16508253 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23299530 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23299530 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 19900491 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21482091 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12919709 — Surrogate Endpoint (SUR): Bone mineral density
Study 9041463 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9041463 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 9041463 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 28329789 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 28329789 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7470200 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11409458 — Surrogate Endpoint (SUR): Bone mineral density
Study 7886407 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3525768 — Predictive Biomarker (PRD): VCP mRNA
Genes: VCP
Study 23690342 — Predictive Biomarker (PRD): SIGLEC12 mRNA
Genes: SIGLEC12; SIGLECL1; SLG; UNQ9215/PRO34042
Study 23690342 — Predictive Biomarker (PRD): A1BG mRNA
Genes: A1BG
Study 23690342 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 20427734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20427734 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20427734 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 12825855 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 29939261 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 29939261 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22303592 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9068554 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 16397516 — Surrogate Endpoint (SUR): Blood pressure
Study 11069371 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 25633713 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25633713 — Predictive Biomarker (PRD): CLEC9A mRNA
Genes: CLEC9A; UNQ9341/PRO34046
Study 18239661 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18239661 — Surrogate Endpoint (SUR): Blood pressure
Study 28477718 — Surrogate Endpoint (SUR): Blood pressure
Study 17116941 — Predictive Biomarker (PRD): Hormone receptor
Study 9542575 — Surrogate Endpoint (SUR): Blood pressure
Study 27505322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27505322 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 18989992 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 1580285 — Surrogate Endpoint (SUR): Blood pressure
Study 6342352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30833491 — Surrogate Endpoint (SUR): Serum creatinine
Study 15063813 — Surrogate Endpoint (SUR): Bone mineral density
Study 31083232 — Predictive Biomarker (PRD): NFKB2 mRNA
Genes: NFKB2; LYT10
Study 31083232 — Predictive Biomarker (PRD): RELA mRNA
Genes: RELA; NFKB3
Study 31083232 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 31083232 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31083232 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30207526 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20139674 — Surrogate Endpoint (SUR): Blood pressure
Study 10348358 — Surrogate Endpoint (SUR): Blood pressure
Study 26313229 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 19947264 — Surrogate Endpoint (SUR): Bone mineral density
Study 17711715 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15144473 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 9646001 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28292282 — Surrogate Endpoint (SUR): Blood pressure
Study 23463651 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 23463651 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 19064281 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 19064281 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10844622 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10844622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29334721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12445840 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 6428171 — Surrogate Endpoint (SUR): Blood pressure
Study 31983031 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19415350 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 17000910 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30379212 — Predictive Biomarker (PRD): SLA mRNA
Genes: SLA; SLAP; SLAP1
Study 22914465 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 31060367 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 28826290 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22629163 — Predictive Biomarker (PRD): LGSN mRNA
Genes: LGSN; GLULD1; LGS
Study 31742903 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 28564564 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17479860 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 17479860 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17479860 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 7995864 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 7995864 — Predictive Biomarker (PRD): SAT2 mRNA
Genes: SAT2; SSAT2
Study 17068305 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 17068305 — Surrogate Endpoint (SUR): Blood pressure
Study 25456979 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 16537575 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 16537575 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16537575 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29716436 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 29716436 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 17646272 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SOD2 mRNA
Genes: SOD2
Study 12390315 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2184945 — Surrogate Endpoint (SUR): Blood pressure
Study 14996880 — Safety Biomarker (SAF): Hyaluronic acid
Study 8195450 — Surrogate Endpoint (SUR): Blood pressure
Study 17181436 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 3536890 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 25148234 — Surrogate Endpoint (SUR): Bone mineral density
Study 16320099 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 12439210 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12439210 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22727707 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 15184351 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15184351 — Surrogate Endpoint (SUR): Blood pressure
Study 15184351 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15184351 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15184351 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9676028 — Predictive Biomarker (PRD): PAFAH1B1 mRNA
Genes: PAFAH1B1; LIS1; MDCR; MDS; PAFAHA
Study 8618802 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 2815979 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28549220 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 26465394 — Surrogate Endpoint (SUR): Bone mineral density
Study 20967458 — Safety Biomarker (SAF): Reactive oxygen species
Study 20967458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 2642486 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2642486 — Surrogate Endpoint (SUR): Blood pressure
Study 28500244 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19429918 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 7757318 — Surrogate Endpoint (SUR): Blood pressure
Study 6773532 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23633272 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23633272 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23633272 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21170107 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21170107 — Surrogate Endpoint (SUR): Blood pressure
Study 9655161 — Surrogate Endpoint (SUR): Serum sodium
Study 24038489 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 24038489 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27747984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17456839 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11714206 — Surrogate Endpoint (SUR): Blood pressure
Study 9806670 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2781421 — Surrogate Endpoint (SUR): Blood pressure
Study 16822276 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 16822276 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16822276 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11434709 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 11434709 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28777983 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 8914876 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6407278 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6407278 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28479178 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 26385034 — Surrogate Endpoint (SUR): Blood pressure
Study 19502264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19502264 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 19502264 — Monitoring Biomarker (MOI): Complement C4
Study 17331985 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 17331985 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 16260974 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12243599 — Surrogate Endpoint (SUR): Blood pressure
Study 22405094 — Safety Biomarker (SAF): Hyaluronic acid
Study 19196729 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25846071 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 7141605 — Surrogate Endpoint (SUR): Blood pressure
Study 24140383 — Surrogate Endpoint (SUR): Blood pressure
Study 20220044 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 20220044 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 10048793 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 26743431 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 8193609 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8193609 — Surrogate Endpoint (SUR): Blood pressure
Study 28569519 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 16769782 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11466259 — Surrogate Endpoint (SUR): Blood pressure
Study 15718838 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15718838 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15718838 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18521540 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 11237499 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 28941998 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 27322745 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 22112743 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 22112743 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22112743 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 20531018 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18262192 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25892647 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30782000 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 21147421 — Surrogate Endpoint (SUR): Blood pressure
Study 1329742 — Safety Biomarker (SAF): Cytochrome c
Study 1329742 — Safety Biomarker (SAF): Succinate dehydrogenase
Genes: SDHD
Study 1329742 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Mitochondrial DNA
Study 11460523 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26258311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18246678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8023668 — Surrogate Endpoint (SUR): Blood pressure
Study 2645918 — Surrogate Endpoint (SUR): Blood pressure
Study 27863326 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 25700289 — Predictive Biomarker (PRD): RNPEP mRNA
Genes: RNPEP; APB
Study 22672611 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21123762 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 21123762 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 21123762 — Surrogate Endpoint (SUR): Blood pressure
Study 10321674 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20640997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25510286 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 15720808 — Predictive Biomarker (PRD): STRAP mRNA
Genes: STRAP; MAWD; UNRIP
Study 11401110 — Surrogate Endpoint (SUR): Serum creatinine
Study 8499097 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 19071883 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 19071883 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 19071883 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 19071883 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19071883 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 12893645 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12893645 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 9012701 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 9012701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8268899 — Surrogate Endpoint (SUR): Blood pressure
Study 16368077 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 23283817 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 23283817 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 23283817 — Predictive Biomarker (PRD): KIT
Genes: CD117; SCFR; C-Kit
Study 8818094 — Surrogate Endpoint (SUR): Blood pressure
Study 2413292 — Surrogate Endpoint (SUR): Blood pressure
Study 26414317 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25455006 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25455006 — Surrogate Endpoint (SUR): Blood pressure
Study 23506685 — Surrogate Endpoint (SUR): Blood pressure
Study 18071721 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26394646 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 26394646 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 24753128 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 24753128 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 22863058 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12615670 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12615670 — Surrogate Endpoint (SUR): Serum triglycerides
Study 2483004 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 10620007 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9020549 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28936572 — Surrogate Endpoint (SUR): Blood pressure
Study 27137122 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 27137122 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 27137122 — Surrogate Endpoint (SUR): Bone mineral density
Study 15904555 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 12322847 — Surrogate Endpoint (SUR): Blood pressure
Study 2156387 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28395659 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28395659 — Surrogate Endpoint (SUR): Serum creatinine
Study 24979561 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 24979561 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 22249272 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 18187961 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 18187961 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29438131 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25051491 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9251961 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3169499 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 3169499 — Surrogate Endpoint (SUR): Serum creatinine
Study 3169499 — Surrogate Endpoint (SUR): Blood pressure
Study 31284074 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23174860 — Surrogate Endpoint (SUR): Blood pressure
Study 21636583 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15580320 — Safety Biomarker (SAF): Cardiac troponin T
Genes: TNNT2
Study 15580320 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 26713491 — Surrogate Endpoint (SUR): Blood pressure
Study 18845806 — Surrogate Endpoint (SUR): Serum uric acid
Study 18845806 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 10569560 — Surrogate Endpoint (SUR): Serum testosterone
Study 9464213 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27686946 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 27686946 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 27686946 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study 25027459 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 22343176 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1907565 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH