TrialPanorama/TrialPanorama-database huggingface dataset:
Study 3673207 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 17565921 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 17658632 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17658632 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11842026 — Surrogate Endpoint (SUR): Blood pressure
Study 28567578 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28567578 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11673582 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 9502190 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30124725 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 30124725 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 26205759 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 26205759 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24604685 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 1792820 — Surrogate Endpoint (SUR): Blood pressure
Study 24906450 — Surrogate Endpoint (SUR): Blood pressure
Study 20197767 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 1889248 — Safety Biomarker (SAF): Interleukin 1
Study 21994966 — Surrogate Endpoint (SUR): Bone mineral density
Study 1711274 — Surrogate Endpoint (SUR): Blood pressure
Study 29510423 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Interleukin 6 receptor alpha
Genes: IL6R
Study 18979450 — Surrogate Endpoint (SUR): Blood pressure
Study 9358957 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29866368 — Surrogate Endpoint (SUR): Blood pressure
Study 29866368 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21319355 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17046300 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2654792 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 2654792 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 18374753 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30592022 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 28256066 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 25063045 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25063045 — Surrogate Endpoint (SUR): Serum creatinine
Study 17173906 — Predictive Biomarker (PRD): SPAG9 mRNA
Genes: SPAG9; HSS; KIAA0516; MAPK8IP4; SYD1; HLC6
Study 15885986 — Predictive Biomarker (PRD): WWTR1 mRNA
Genes: WWTR1; TAZ
Study 8573425 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 28087723 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18534230 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 10071916 — Surrogate Endpoint (SUR): Bone mineral density
Study 7480526 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 7480526 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 23603824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23603824 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23603824 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11572892 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11572892 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8156337 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8156337 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15814212 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8729094 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29967037 — Surrogate Endpoint (SUR): Blood pressure
Study 16228107 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 16228107 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24671897 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20182456 — Surrogate Endpoint (SUR): Blood pressure
Study 15704683 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 11809596 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 11809596 — Safety Biomarker (SAF): Reactive oxygen species
Study 11809596 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1791611 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9327093 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 9327093 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20096897 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20096897 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18029465 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12095664 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12095664 — Surrogate Endpoint (SUR): Blood pressure
Study 2786009 — Predictive Biomarker (PRD): FBL mRNA
Genes: FBL; FIB1; FLRN
Study 31384899 — Predictive Biomarker (PRD): SLA mRNA
Genes: SLA; SLAP; SLAP1
Study 28235974 — Surrogate Endpoint (SUR): Blood pressure
Study 26416653 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 26569501 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11323731 — Surrogate Endpoint (SUR): Blood pressure
Study 7943831 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 7943831 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 24512953 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23464930 — Surrogate Endpoint (SUR): Blood pressure
Study 16860045 — Surrogate Endpoint (SUR): Bone mineral density
Study 14624371 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 14624371 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): CCR2 mRNA
Genes: CCR2; CMKBR2
Study 14624371 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 30292481 — Predictive Biomarker (PRD): STUB1 mRNA
Genes: STUB1; CHIP; PP1131
Study 3034021 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3034021 — Surrogate Endpoint (SUR): Blood pressure
Study 3034021 — Surrogate Endpoint (SUR): Serum uric acid
Study 20099948 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 24393424 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 24393424 — Monitoring Biomarker (MOI): Procalcitonin
Study 8966062 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 28143564 — Surrogate Endpoint (SUR): Blood pressure
Study 26060823 — Safety Biomarker (SAF): DRD2
Study 20671652 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8551786 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8551786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8551786 — Safety Biomarker (SAF): Interleukin 1
Study 8551786 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8551786 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31615771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31615771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20581719 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9350366 — Surrogate Endpoint (SUR): Blood pressure
Study 31779697 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 31779697 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31779697 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 21362524 — Surrogate Endpoint (SUR): Serum creatinine
Study 21362524 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 14622826 — Surrogate Endpoint (SUR): Blood pressure
Study 27276758 — Surrogate Endpoint (SUR): Blood pressure
Study 19842973 — Surrogate Endpoint (SUR): Bone mineral density
Study 16723320 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 25549639 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 22348270 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15925739 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15925739 — Surrogate Endpoint (SUR): Blood pressure
Study 15925739 — Surrogate Endpoint (SUR): Serum potassium
Study 31735560 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 30399455 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22617578 — Surrogate Endpoint (SUR): Blood pressure
Study 20223838 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 11144061 — Predictive Biomarker (PRD): CD55 mRNA
Genes: CD55; CR; DAF
Study 1667693 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 6332953 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22499404 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 22499404 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 11715499 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 2218653 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 23551402 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 23551402 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16123763 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 23660437 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 23660437 — Safety Biomarker (SAF): DRD2
Study 16978648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 27291994 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 23617556 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 15237711 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 15237711 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 15237711 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 12055702 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12055702 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9829494 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 7917157 — Surrogate Endpoint (SUR): Blood pressure
Study 18675477 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19004228 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 27183837 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 23040786 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2213552 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22469418 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21897773 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 14583848 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1539810 — Surrogate Endpoint (SUR): Blood pressure
Study 28453868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28453868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28453868 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28453868 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18683666 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11382623 — Surrogate Endpoint (SUR): Blood pressure
Study 16647994 — Surrogate Endpoint (SUR): Blood pressure
Study 12802027 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29478510 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 29478510 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29478510 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 29478510 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29478510 — Safety Biomarker (SAF): BDNF
Study 2255262 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 31279534 — Predictive Biomarker (PRD): GLDC mRNA
Genes: GLDC; GCSP
Study 26498005 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26498005 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 26498005 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study 26498005 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 20044757 — Surrogate Endpoint (SUR): Bone mineral density
Study 15126582 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11795850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11795850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11795850 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8892775 — Surrogate Endpoint (SUR): Blood pressure
Study 30302666 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30302666 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 20483041 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 30683697 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 30683697 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 30683697 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 30683697 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30683697 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 30683697 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 18254322 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 12393777 — Surrogate Endpoint (SUR): Blood pressure
Study 10439497 — Surrogate Endpoint (SUR): Blood pressure
Study 10439497 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23892409 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 12968987 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10535380 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 10535380 — Predictive Biomarker (PRD): FER mRNA
Genes: FER; TYK3
Study 18469279 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11299816 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 3037813 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 12796769 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17968939 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 31476413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 21219298 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 16026400 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1800302 — Surrogate Endpoint (SUR): Blood pressure
Study 7055378 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 19525084 — Surrogate Endpoint (SUR): Blood pressure
Study 91251 — Predictive Biomarker (PRD): BLM mRNA
Genes: BLM; RECQ2; RECQL3
Study 30947763 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 25347141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25347141 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23475568 — Predictive Biomarker (PRD): POU2F1 mRNA
Genes: POU2F1; OCT1; OTF1
Study 23475568 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 23475568 — Predictive Biomarker (PRD): SLC22A3 mRNA
Genes: SLC22A3; EMTH; OCT3
Study 23475568 — Predictive Biomarker (PRD): SLC47A1 mRNA
Genes: SLC47A1; MATE1
Study 23475568 — Predictive Biomarker (PRD): SLC29A4 mRNA
Genes: SLC29A4; ENT4; PMAT; PSEC0113
Study 19142564 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 19142564 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17275226 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17275226 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7957490 — Surrogate Endpoint (SUR): Blood pressure
Study 7957490 — Surrogate Endpoint (SUR): Serum creatinine
Study 28930874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28930874 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16061828 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 16061828 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8636300 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11189407 — Monitoring Biomarker (MOI): HBV DNA
Study 11189407 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27418685 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 24287500 — Predictive Biomarker (PRD): CX3CR1 mRNA
Genes: CX3CR1; CMKBRL1; GPR13
Study 24287500 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 24287500 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 20418724 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18752863 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18752863 — Monitoring Biomarker (MOI): HBV DNA
Study 7298119 — Surrogate Endpoint (SUR): Blood pressure
Study 18549913 — Surrogate Endpoint (SUR): Serum uric acid
Study 2056904 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7046680 — Surrogate Endpoint (SUR): Blood pressure
Study 27534671 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9988788 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3315272 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 24508492 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 23149928 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study 15678250 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10072218 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28933876 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 15342900 — Surrogate Endpoint (SUR): Blood pressure
Study 10411845 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7975772 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 7975772 — Predictive Biomarker (PRD): BSG mRNA
Genes: BSG; UNQ6505/PRO21383
Study 7975772 — Predictive Biomarker (PRD): BSN mRNA
Genes: BSN; KIAA0434; ZNF231
Study 3393494 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 3393494 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 23754097 — Surrogate Endpoint (SUR): Blood pressure
Study 20102058 — Surrogate Endpoint (SUR): Blood pressure
Study 8406294 — Surrogate Endpoint (SUR): Blood pressure
Study 8688987 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 2203322 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2203322 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20358359 — Surrogate Endpoint (SUR): Bone mineral density
Study 15036822 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11377600 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9203805 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 10803924 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 1432499 — Surrogate Endpoint (SUR): Blood pressure
Study 27109453 — Predictive Biomarker (PRD): NR1H4 mRNA
Genes: NR1H4; BAR; FXR; HRR1; RIP14
Study 23994506 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 14748815 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 14748815 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 14748815 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 14748815 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 14748815 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8993996 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31537233 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31537233 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 31537233 — Surrogate Endpoint (SUR): Serum creatinine
Study 8710157 — Surrogate Endpoint (SUR): Blood pressure
Study 17959988 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TNS1 mRNA
Genes: TNS1; TNS
Study 23239872 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 16797409 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10694834 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 10694834 — Surrogate Endpoint (SUR): Blood pressure
Study 11874944 — Surrogate Endpoint (SUR): Blood pressure
Study 11874944 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 11874944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17284733 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9398965 — Surrogate Endpoint (SUR): Blood pressure
Study 26365452 — Surrogate Endpoint (SUR): Blood pressure
Study 16462287 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21496343 — Predictive Biomarker (PRD): DPT mRNA
Genes: DPT
Study 11093966 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 9088819 — Surrogate Endpoint (SUR): Blood pressure
Study 29151280 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20681273 — Predictive Biomarker (PRD): SI mRNA
Genes: SI