TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28182820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28182820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28182820 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 28182820 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24314824 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 15373934 — Surrogate Endpoint (SUR): Blood pressure
Study 9011463 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 15165613 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31982148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31982148 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31982148 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31570429 — Predictive Biomarker (PRD): ANO7 mRNA
Genes: ANO7; NGEP; PCANAP5; TMEM16G
Study 15031430 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 6998872 — Surrogate Endpoint (SUR): Blood pressure
Study 6998872 — Surrogate Endpoint (SUR): Serum sodium
Study 29722252 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28616715 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 24080992 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 24080992 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 24080992 — Surrogate Endpoint (SUR): Bone mineral density
Study 17143195 — Surrogate Endpoint (SUR): Blood pressure
Study 9039836 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 2087150 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 28689036 — Surrogate Endpoint (SUR): Serum creatinine
Study 20957391 — Surrogate Endpoint (SUR): Blood pressure
Study 20957391 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14969650 — Surrogate Endpoint (SUR): Blood pressure
Study 31564046 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study 29653820 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12494207 — Surrogate Endpoint (SUR): Blood pressure
Study 7877305 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 8903664 — Surrogate Endpoint (SUR): Blood pressure
Study 10605180 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 30193843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30193843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12051573 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7728405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28627980 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15469648 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 11289332 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2647896 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 19043376 — Surrogate Endpoint (SUR): Bone mineral density
Study 7379443 — Surrogate Endpoint (SUR): Blood pressure
Study 19033683 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 18167250 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9703298 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2644144 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2644144 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24633493 — Surrogate Endpoint (SUR): Bone mineral density
Study 19423079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17443133 — Surrogate Endpoint (SUR): Blood pressure
Study 31087530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31087530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22431837 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 31562796 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26253612 — Predictive Biomarker (PRD): MTIF3 mRNA
Genes: MTIF3; DC38
Study 21530317 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 16497685 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16497685 — Surrogate Endpoint (SUR): Blood pressure
Study 12867351 — Surrogate Endpoint (SUR): Blood pressure
Study 30009729 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 26701977 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 24386861 — Predictive Biomarker (PRD): PDZD2 mRNA
Genes: PDZD2; AIPC; KIAA0300; PDZK3
Study 24386861 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 24386861 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 18821290 — Surrogate Endpoint (SUR): Bone mineral density
Study 18821290 — Surrogate Endpoint (SUR): Serum testosterone
Study 20393454 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 10726961 — Surrogate Endpoint (SUR): Blood pressure
Study 29752028 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 20194698 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 10489947 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1827014 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30350117 — Surrogate Endpoint (SUR): Blood pressure
Study 14985887 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 11737399 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8273984 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 27646264 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27646264 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 27646264 — Surrogate Endpoint (SUR): Blood pressure
Study 18317424 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 13680036 — Surrogate Endpoint (SUR): Blood pressure
Study 29705444 — Surrogate Endpoint (SUR): Blood pressure
Study 12842840 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10832123 — Surrogate Endpoint (SUR): Blood pressure
Study 1639462 — Surrogate Endpoint (SUR): Blood pressure
Study 31117149 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 28341106 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19337944 — Safety Biomarker (SAF): Hyaluronic acid
Study 16849403 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 8477962 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8477962 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20526599 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 16497254 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12559536 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 15806263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26664107 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19926008 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22252800 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 16130059 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8757425 — Predictive Biomarker (PRD): TNFR1B
Genes: TNFRSF1B; TNFBR; TNFR80; TNF-R75; TNF-R-II; p75; CD120b
Study 8757425 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8757425 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24436491 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22952598 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11132612 — Surrogate Endpoint (SUR): Blood pressure
Study 11132612 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9113185 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27474536 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 21988742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24859410 — Surrogate Endpoint (SUR): Serum calcium
Study 10632415 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 3082287 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 18234488 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 10100554 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7091024 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 27605086 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 23380230 — Safety Biomarker (SAF): Hyaluronic acid
Study 2375945 — Surrogate Endpoint (SUR): Blood pressure
Study 1096218 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 31049747 — Surrogate Endpoint (SUR): Serum creatinine
Study 21504334 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 31547752 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23442371 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 23442371 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23442371 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19749496 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16802360 — Surrogate Endpoint (SUR): Bone mineral density
Study 9305226 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 29307660 — Surrogate Endpoint (SUR): Serum calcium
Study 23000961 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 12695418 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 29699885 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29699885 — Surrogate Endpoint (SUR): Blood pressure
Study 20091486 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26775477 — Surrogate Endpoint (SUR): Blood pressure
Study 18046226 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 15501952 — Surrogate Endpoint (SUR): Pathological complete response
Study 3148366 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 25234648 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 10746426 — Surrogate Endpoint (SUR): Bone mineral density
Study 8636828 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27515419 — Surrogate Endpoint (SUR): Blood pressure
Study 12005317 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study 24696507 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 20203165 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20203165 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 20203165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15297165 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8206772 — Surrogate Endpoint (SUR): Blood pressure
Study 30882244 — Predictive Biomarker (PRD): DBH mRNA
Genes: DBH
Study 30882244 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 30882244 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28838366 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25223696 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 16060912 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 10599554 — Surrogate Endpoint (SUR): Bone mineral density
Study 8541006 — Surrogate Endpoint (SUR): Blood pressure
Study 2024543 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2024543 — Surrogate Endpoint (SUR): Serum creatinine
Study 2024543 — Surrogate Endpoint (SUR): Blood pressure
Study 6168856 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6168856 — Surrogate Endpoint (SUR): Blood pressure
Study 26975533 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20639832 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 15821100 — Predictive Biomarker (PRD): HES1 mRNA
Genes: HES1; BHLHB39; HL; HRY
Study 11909567 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29100550 — Surrogate Endpoint (SUR): Blood pressure
Study 29100550 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 20663491 — Predictive Biomarker (PRD): KLK3 mRNA
Genes: KLK3; APS
Study 15785218 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30958058 — Safety Biomarker (SAF): Interleukin 1
Study 9159735 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 8267111 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 3115131 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 25420434 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21716318 — Surrogate Endpoint (SUR): Blood pressure
Study 18703471 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15615822 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15615822 — Surrogate Endpoint (SUR): Serum creatinine
Study 30132821 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9773139 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 9773139 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29057618 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 15593038 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 28040692 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 21407110 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21407110 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 21407110 — Safety Biomarker (SAF): IL-6 and IL-10
Study 8420296 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8420296 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3749299 — Surrogate Endpoint (SUR): Blood pressure
Study 28135883 — Safety Biomarker (SAF): Hyaluronic acid
Study 23311248 — Pharmacodynamic Biomarker (PDY): Lysosomal acid glucosylceramidase
Genes: GBA1; GBA; GC; GLUC
Study 920252 — Predictive Biomarker (PRD): OTOR mRNA
Genes: OTOR; FDP; MIAL; UNQ3054/PRO9873
Study 31713129 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31713129 — Surrogate Endpoint (SUR): Blood pressure
Study 15579515 — Surrogate Endpoint (SUR): Serum creatinine
Study 29888547 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 29888547 — Surrogate Endpoint (SUR): Blood pressure
Study 25119686 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22361399 — Safety Biomarker (SAF): Reactive oxygen species
Study 7430504 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12424822 — Surrogate Endpoint (SUR): Bone mineral density
Study 7544524 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study 6909683 — Surrogate Endpoint (SUR): Serum sodium
Study 21896198 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 12646340 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12646340 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10068342 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11039639 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 8970607 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30176391 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 30176391 — Surrogate Endpoint (SUR): Bone mineral density
Study 26275787 — Surrogate Endpoint (SUR): Blood pressure
Study 22465901 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15905884 — Surrogate Endpoint (SUR): Blood pressure
Study 7735336 — Predictive Biomarker (PRD): ABL2 mRNA
Genes: ABL2; ABLL; ARG
Study 7735336 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 29150790 — Surrogate Endpoint (SUR): Serum creatinine
Study 23372142 — Surrogate Endpoint (SUR): Blood pressure
Study 21912808 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 21912808 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 16646722 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): C-X-C motif chemokine 9
Genes: CXCL9; CMK; MIG; SCYB9
Study 11025952 — Surrogate Endpoint (SUR): Blood pressure
Study 8311271 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3396573 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26603531 — Surrogate Endpoint (SUR): Blood pressure
Study 22928779 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 9140674 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9140674 — Surrogate Endpoint (SUR): Blood pressure
Study 24040156 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 19318695 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19318695 — Surrogate Endpoint (SUR): Blood pressure
Study 15576069 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8066866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18077012 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8320622 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31512487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31512487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24642648 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 24642648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11867042 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11867042 — Surrogate Endpoint (SUR): Blood pressure
Study 11867042 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26527536 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 31805968 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12784700 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 9862579 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 12741422 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10971308 — Surrogate Endpoint (SUR): Blood pressure
Study 19559965 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 19559965 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 17623745 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7966415 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 1632100 — Surrogate Endpoint (SUR): Blood pressure
Study 29695594 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 26847290 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22872468 — Surrogate Endpoint (SUR): Serum calcium
Study 20688261 — Surrogate Endpoint (SUR): Blood pressure
Study 26684633 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24857299 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15809366 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15809366 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12182234 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1954179 — Safety Biomarker (SAF): Epiregulin
Genes: EREG
Study 25635593 — Surrogate Endpoint (SUR): Blood pressure
Study 1483491 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 29070503 — Predictive Biomarker (PRD): C1QTNF3 mRNA
Genes: C1QTNF3; CTRP3; UNQ753/PRO1484
Study 12131247 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 12131247 — Surrogate Endpoint (SUR): Blood pressure
Study 28115517 — Surrogate Endpoint (SUR): Blood pressure
Study 2920499 — Surrogate Endpoint (SUR): Blood pressure
Study 25516462 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21247415 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20003300 — Surrogate Endpoint (SUR): Blood pressure
Study 16150956 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 26604072 — Surrogate Endpoint (SUR): Blood pressure
Study 22408123 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1