TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19543080 — Surrogate Endpoint (SUR): Blood pressure
Study 11269535 — Surrogate Endpoint (SUR): Bone mineral density
Study 29250152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29250152 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29250152 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 25711321 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20947492 — Predictive Biomarker (PRD): GAL3ST1 mRNA
Genes: GAL3ST1; CST
Study 10945091 — Surrogate Endpoint (SUR): Blood pressure
Study 31257439 — Predictive Biomarker (PRD): ASPSCR1 mRNA
Genes: ASPSCR1; ASPL; RCC17; TUG; UBXD9; UBXN9
Study 31257439 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 22198049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22198049 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22198049 — Safety Biomarker (SAF): Reactive oxygen species
Study 17385970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17984132 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 8853730 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 6438683 — Predictive Biomarker (PRD): CPZ mRNA
Genes: CPZ
Study 31256717 — Surrogate Endpoint (SUR): Blood pressure
Study 29744647 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 17907109 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 17907109 — Surrogate Endpoint (SUR): Serum creatinine
Study 30268346 — Surrogate Endpoint (SUR): Blood pressure
Study 28122337 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28122337 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 6401908 — Surrogate Endpoint (SUR): Blood pressure
Study 25323254 — Surrogate Endpoint (SUR): Blood pressure
Study 19124377 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 30256303 — Surrogate Endpoint (SUR): Blood pressure
Study 10321414 — Surrogate Endpoint (SUR): Blood pressure
Study 25545313 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22622138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 22622138 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8770800 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 23421600 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25112372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25112372 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19738493 — Surrogate Endpoint (SUR): Blood pressure
Study 20354006 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18764823 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8621129 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 8621129 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 8621129 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16916334 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 2109473 — Surrogate Endpoint (SUR): Blood pressure
Study 9197016 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9197016 — Surrogate Endpoint (SUR): Blood pressure
Study 20972736 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12448341 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22672359 — Surrogate Endpoint (SUR): Bone mineral density
Study 22672359 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10709370 — Surrogate Endpoint (SUR): Blood pressure
Study 9071556 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 7527736 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 23388588 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 14627440 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14627440 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9380298 — Surrogate Endpoint (SUR): Bone mineral density
Study 10554120 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10554120 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8622041 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8365461 — Surrogate Endpoint (SUR): Serum creatinine
Study 22343976 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 20186278 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20186278 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15980686 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12705178 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 12705178 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 28854580 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 26346470 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 26346470 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23287836 — Surrogate Endpoint (SUR): Bone mineral density
Study 22724916 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 22724916 — Surrogate Endpoint (SUR): Blood pressure
Study 21076271 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10736331 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 8737101 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 23163142 — Surrogate Endpoint (SUR): Serum creatinine
Study 23163142 — Surrogate Endpoint (SUR): Blood pressure
Study 18083668 — Surrogate Endpoint (SUR): Forced vital capacity
Study 15653517 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 12567031 — Pharmacodynamic Biomarker (PDY): Complement C5
Genes: C5; CPAMD4
Study 11815315 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 9710711 — Surrogate Endpoint (SUR): Bone mineral density
Study 7663660 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27869649 — Predictive Biomarker (PRD): TSLP mRNA
Genes: TSLP
Study 27869649 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study 27869649 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26384238 — Predictive Biomarker (PRD): RARA mRNA
Genes: RARA; NR1B1
Study 26384238 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16621098 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 16621098 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29449506 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 29449506 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29188889 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 16571878 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 14605279 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 8708224 — Surrogate Endpoint (SUR): Blood pressure
Study 9627274 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9627274 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 23334268 — Surrogate Endpoint (SUR): Probing pocket depth
Study 1425877 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1425877 — Surrogate Endpoint (SUR): Blood pressure
Study 31156013 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 25997746 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15016485 — Surrogate Endpoint (SUR): Blood pressure
Study 11703421 — Surrogate Endpoint (SUR): Blood pressure
Study 7536071 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24712568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24712568 — Surrogate Endpoint (SUR): Blood pressure
Study 9795914 — Monitoring Biomarker (MOI): HBV DNA
Study 12518705 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 9381885 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 21383284 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 9551878 — Surrogate Endpoint (SUR): Blood pressure
Study 30012268 — Surrogate Endpoint (SUR): Blood pressure
Study 28965562 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 26485846 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 30573517 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 27000327 — Surrogate Endpoint (SUR): Blood pressure
Study 22789789 — Surrogate Endpoint (SUR): Blood pressure
Study 22789789 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9817281 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9817281 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30123250 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 24983542 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 24983542 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19602554 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19602554 — Surrogate Endpoint (SUR): Serum triglycerides
Study 8012963 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28028737 — Surrogate Endpoint (SUR): Serum testosterone
Study 17204725 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 1525787 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2859042 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28371155 — Surrogate Endpoint (SUR): Blood pressure
Study 26659938 — Safety Biomarker (SAF): Hyaluronic acid
Study 21658668 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 27301417 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19460715 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 17627399 — Surrogate Endpoint (SUR): Blood pressure
Study 29304531 — Predictive Biomarker (PRD): SKIL mRNA
Genes: SKIL; SNO
Study 23290154 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31605923 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 23877621 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 30819077 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30819077 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30819077 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15260911 — Surrogate Endpoint (SUR): Blood pressure
Study 11726259 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11726259 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 9159031 — Predictive Biomarker (PRD): F2R mRNA
Genes: F2R; CF2R; PAR1; TR
Study 9159031 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 9159031 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30144017 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 30144017 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 30144017 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25654961 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 21323524 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 19369086 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 14625708 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9494591 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 9494591 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9494591 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 29624887 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29624887 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15333465 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 15333465 — Predictive Biomarker (PRD): APEX1 mRNA
Genes: APEX1; APE; APE1; APEX; APX; HAP1; REF1
Study 15333465 — Predictive Biomarker (PRD): XRCC3 mRNA
Genes: XRCC3
Study 11789775 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30028478 — Predictive Biomarker (PRD): NXF1 mRNA
Genes: NXF1; TAP
Study 14503058 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 14503058 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26631181 — Surrogate Endpoint (SUR): Blood pressure
Study 23849625 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 22052266 — Safety Biomarker (SAF): Hyaluronic acid
Study 16495194 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 16495194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16495194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17109305 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11996958 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 9578185 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9578185 — Surrogate Endpoint (SUR): Blood pressure
Study 24158983 — Surrogate Endpoint (SUR): Serum creatinine
Study 15257186 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15257186 — Surrogate Endpoint (SUR): Blood pressure
Study 31615937 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31615937 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24690201 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 16322468 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 8781902 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 6372563 — Surrogate Endpoint (SUR): Serum sodium
Study 20007923 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20007923 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25127090 — Surrogate Endpoint (SUR): Urine free cortisol
Study 15919695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15919695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9094887 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8104091 — Surrogate Endpoint (SUR): Blood pressure
Study 31323295 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12685513 — Surrogate Endpoint (SUR): Blood pressure
Study 12411535 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 6761851 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 28740213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21623963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21623963 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21623963 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21623963 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19042945 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 19042945 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 15718406 — Surrogate Endpoint (SUR): Blood pressure
Study 2432009 — Surrogate Endpoint (SUR): Blood pressure
Study 27849166 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 27849166 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 25061688 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 22726372 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 21098580 — Surrogate Endpoint (SUR): Blood pressure
Study 16351673 — Predictive Biomarker (PRD): GSS mRNA
Genes: GSS
Study 1752116 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 1752116 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28356068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28356068 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 28356068 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26921645 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 11506819 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 9743394 — Surrogate Endpoint (SUR): Blood pressure
Study 31028957 — Surrogate Endpoint (SUR): Bone mineral density
Study 19262499 — Surrogate Endpoint (SUR): Blood pressure
Study 8922197 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26009799 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 19572829 — Predictive Biomarker (PRD): MAX mRNA
Genes: MAX; BHLHD4
Study 12888152 — Surrogate Endpoint (SUR): Blood pressure
Study 1873002 — Surrogate Endpoint (SUR): Blood pressure
Study 26669919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26669919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23778432 — Surrogate Endpoint (SUR): Blood pressure
Study 27401319 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27401319 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 27401319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17968992 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 16221106 — Surrogate Endpoint (SUR): Serum creatinine
Study 17560254 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 17560254 — Surrogate Endpoint (SUR): Serum calcium
Study 9331015 — Surrogate Endpoint (SUR): Blood pressure
Study 22854954 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22854954 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20332484 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 17070962 — Surrogate Endpoint (SUR): Pathological complete response
Study 15636137 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 26049975 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 26049975 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24332196 — Surrogate Endpoint (SUR): Blood pressure
Study 19112032 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 19112032 — Predictive Biomarker (PRD): ACD mRNA
Genes: ACD; PIP1; PTOP; TINT1; TPP1
Study 19112032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19112032 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 19112032 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 19112032 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20890933 — Surrogate Endpoint (SUR): Bone mineral density
Study 9108642 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 8474201 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 24588407 — Predictive Biomarker (PRD): MAP3K10 mRNA
Genes: MAP3K10; MLK2; MST
Study 23350899 — Surrogate Endpoint (SUR): Blood pressure
Study 21813900 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14564337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 6318224 — Surrogate Endpoint (SUR): Blood pressure
Study 29853235 — Safety Biomarker (SAF): OPRM1
Genes: MOR1; MOP
Study 22891212 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20587704 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20587704 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 7782965 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16253719 — Surrogate Endpoint (SUR): Blood pressure
Study 16253719 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23271305 — Predictive Biomarker (PRD): USF1 mRNA
Genes: USF1; BHLHB11; USF
Study 23271305 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23271305 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21645007 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10831287 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 10831287 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20191485 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24845190 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 20844075 — Surrogate Endpoint (SUR): Blood pressure
Study 2296627 — Surrogate Endpoint (SUR): Blood pressure