TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24907722 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17587398 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 12698086 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22964967 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 26054147 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 26054147 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 26054147 — Surrogate Endpoint (SUR): Blood pressure
Study 24122908 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15135261 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 9610754 — Surrogate Endpoint (SUR): Bone mineral density
Study 22185725 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 17050637 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 17050637 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 17050637 — Safety Biomarker (SAF): Cytochrome c
Study 17050637 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 17050637 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 17050637 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 17050637 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12808614 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7669957 — Surrogate Endpoint (SUR): Blood pressure
Study 2185293 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 28548626 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8636558 — Surrogate Endpoint (SUR): Blood pressure
Study 1637970 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CARTPT mRNA
Genes: CARTPT; CART
Study 28176893 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25523837 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19841299 — Surrogate Endpoint (SUR): Serum creatinine
Study 17078183 — Surrogate Endpoint (SUR): Blood pressure
Study 14745710 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2487463 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 26618460 — Safety Biomarker (SAF): Hyaluronic acid
Study 26253887 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 26253887 — Surrogate Endpoint (SUR): Serum creatinine
Study 15692762 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 7556989 — Surrogate Endpoint (SUR): Blood pressure
Study 7556989 — Surrogate Endpoint (SUR): Serum potassium
Study 22288567 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 22288567 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10594487 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 10594487 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 10594487 — Predictive Biomarker (PRD): CYP2E1 mRNA
Genes: CYP2E1; CYP2E
Study 10594487 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 10594487 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 10594487 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 29267900 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29267900 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29267900 — Safety Biomarker (SAF): Derived neutrophil to lymphocyte
Study 29267900 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study 26874645 — Surrogate Endpoint (SUR): Serum sodium
Study 22740283 — Surrogate Endpoint (SUR): Bone mineral density
Study 19554028 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19554028 — Surrogate Endpoint (SUR): Blood pressure
Study 17506866 — Surrogate Endpoint (SUR): Blood pressure
Study 11927516 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 11927516 — Surrogate Endpoint (SUR): Blood pressure
Study 2683546 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2683546 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 14719288 — Safety Biomarker (SAF): Hyaluronic acid
Study 11110056 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8986909 — Surrogate Endpoint (SUR): Blood pressure
Study 8986909 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7708425 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26927664 — Predictive Biomarker (PRD): CR1 mRNA
Genes: CR1; C3BR
Study 16625235 — Surrogate Endpoint (SUR): Blood pressure
Study 8677878 — Surrogate Endpoint (SUR): Serum potassium
Study 1659913 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31036542 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31036542 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9772873 — Surrogate Endpoint (SUR): Blood pressure
Study 2510657 — Surrogate Endpoint (SUR): Blood pressure
Study 25877802 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24157649 — Surrogate Endpoint (SUR): Blood pressure
Study 20390343 — Predictive Biomarker (PRD): Hormone receptor
Study 16110017 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 12355185 — Surrogate Endpoint (SUR): Blood pressure
Study 2341751 — Surrogate Endpoint (SUR): Serum calcium
Study 11543695 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18326616 — Surrogate Endpoint (SUR): Bone mineral density
Study 15528283 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12854177 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 29478970 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 29478970 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 10569660 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6482180 — Surrogate Endpoint (SUR): Blood pressure
Study 17707851 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11893228 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 7610938 — Surrogate Endpoint (SUR): Serum calcium
Study 19384185 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 19939467 — Predictive Biomarker (PRD): GJB2 mRNA
Genes: GJB2
Study 17414902 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 31784280 — Predictive Biomarker (PRD): MFAP4 mRNA
Genes: MFAP4
Study 29938621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29938621 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27809886 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 25157115 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8123862 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 21297494 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21297494 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15705206 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12074350 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 11106916 — Surrogate Endpoint (SUR): Bone mineral density
Study 11106916 — Surrogate Endpoint (SUR): Serum testosterone
Study 24559095 — Predictive Biomarker (PRD): YAP1 mRNA
Genes: YAP1; YAP65
Study 24559095 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20920186 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12211218 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 21862012 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 21862012 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study 9399388 — Surrogate Endpoint (SUR): Bone mineral density
Study 2975595 — Surrogate Endpoint (SUR): Blood pressure
Study 15579575 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25336703 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A2 mRNA
Genes: SRD5A2
Study 25336703 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12610024 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 2385209 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study 6994760 — Surrogate Endpoint (SUR): Blood pressure
Study 29953014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23013731 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 23013731 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 20047770 — Surrogate Endpoint (SUR): Blood pressure
Study 20047770 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16936007 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 25218876 — Surrogate Endpoint (SUR): Blood pressure
Study 25218876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25218876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30376366 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 27125363 — Surrogate Endpoint (SUR): Bone mineral density
Study 1926024 — Surrogate Endpoint (SUR): Forced vital capacity
Study 11122797 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 29056520 — Predictive Biomarker (PRD): VCAM1 mRNA
Genes: VCAM1
Study 29056520 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 24647737 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24647737 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16244024 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16244024 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16244024 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12107602 — Surrogate Endpoint (SUR): Blood pressure
Study 1903079 — Predictive Biomarker (PRD): DEK mRNA
Genes: DEK
Study 21785889 — Predictive Biomarker (PRD): CGAS mRNA
Genes: CGAS; C6orf150; MB21D1
Study 17440643 — Surrogate Endpoint (SUR): Blood pressure
Study 17410124 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23723343 — Surrogate Endpoint (SUR): Blood pressure
Study 17255304 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study 17255304 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15124757 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 7898227 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31389909 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31389909 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31389909 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28255102 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23414490 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23677653 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8883120 — Surrogate Endpoint (SUR): Bone mineral density
Study 24638013 — Predictive Biomarker (PRD): DNA excision repair protein ERCC-1
Genes: ERCC1
Study 24638013 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 7912725 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 21757458 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20071896 — Surrogate Endpoint (SUR): Blood pressure
Study 16492702 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 16492702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16492702 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16492702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16492702 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 3510822 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30032977 — Surrogate Endpoint (SUR): Blood pressure
Study 17931408 — Surrogate Endpoint (SUR): Blood pressure
Study 10839761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10839761 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29747957 — Surrogate Endpoint (SUR): Blood pressure
Study 22418581 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15590212 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 15590212 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 15590212 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 15590212 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 29020251 — Surrogate Endpoint (SUR): Blood pressure
Study 17518957 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 27618821 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23890047 — Surrogate Endpoint (SUR): Blood pressure
Study 19384192 — Surrogate Endpoint (SUR): Blood pressure
Study 2024569 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30715452 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25308787 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21694537 — Surrogate Endpoint (SUR): Fecal coefficient of fat absorption
Study 8306366 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8306366 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12707981 — Surrogate Endpoint (SUR): Bone mineral density
Study 1451716 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8590895 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2666454 — Surrogate Endpoint (SUR): Blood pressure
Study 25561135 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10440307 — Surrogate Endpoint (SUR): Serum sodium
Study 30312457 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30312457 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 20216558 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20216558 — Surrogate Endpoint (SUR): Blood pressure
Study 20216558 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12077724 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 29232438 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 19166685 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 31199501 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 31199501 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 31199501 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31199501 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 26939313 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26939313 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16705841 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28730676 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23525453 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23525453 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23525453 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18568412 — Surrogate Endpoint (SUR): Serum calcium
Study 27687379 — Surrogate Endpoint (SUR): Blood pressure
Study 10664640 — Surrogate Endpoint (SUR): Blood pressure
Study 10664640 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22793964 — Surrogate Endpoint (SUR): Blood pressure
Study 10367603 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6629620 — Surrogate Endpoint (SUR): Blood pressure
Study 29532983 — Surrogate Endpoint (SUR): Blood pressure
Study 1828765 — Surrogate Endpoint (SUR): Blood pressure
Study 30586730 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19349543 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 30970057 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 22183134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22183134 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25211775 — Surrogate Endpoint (SUR): Blood pressure
Study 17369710 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 17369710 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15725144 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9864836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9864836 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31063856 — Surrogate Endpoint (SUR): Blood pressure
Study 31063856 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26406087 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26406087 — Predictive Biomarker (PRD): SLC10A3 mRNA
Genes: SLC10A3; DXS253E; P3
Study 26406087 — Predictive Biomarker (PRD): PDIA6 mRNA
Genes: PDIA6; ERP5; P5; TXNDC7
Study 20940639 — Surrogate Endpoint (SUR): Blood pressure
Study 23711593 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 11535206 — Surrogate Endpoint (SUR): Blood pressure
Study 8068601 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8068601 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27879326 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 1409770 — Surrogate Endpoint (SUR): Blood pressure
Study 30891808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9793664 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15904653 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15904653 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31759587 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31759587 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 31759587 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 23130675 — Predictive Biomarker (PRD): CFP mRNA
Genes: CFP; PFC
Study 24636210 — Surrogate Endpoint (SUR): Bone mineral density
Study 20404221 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 10475291 — Surrogate Endpoint (SUR): Blood pressure
Study 17522508 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 31713753 — Predictive Biomarker (PRD): CPD mRNA
Genes: CPD
Study 26802811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26802811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20417243 — Safety Biomarker (SAF): MTHFR
Study 15790610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11932303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11932303 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7752668 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30383918 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 30383918 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30383918 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 31047298 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 31047298 — Predictive Biomarker (PRD): TRIM63 mRNA
Genes: TRIM63; IRF; MURF1; RNF28; SMRZ
Study 27832073 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 27832073 — Predictive Biomarker (PRD): AKR1C1 mRNA
Genes: AKR1C1; DDH; DDH1
Study 27832073 — Predictive Biomarker (PRD): AKR1C3 mRNA
Genes: AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
Study 19240980 — Surrogate Endpoint (SUR): Bone mineral density
Study 31765263 — Predictive Biomarker (PRD): MLH1 mRNA
Genes: MLH1; COCA2
Study 31765263 — Predictive Biomarker (PRD): DNA mismatch repair protein MSH2
Genes: MSH2
Study 23843473 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 1867231 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1867231 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30591094 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23847109 — Surrogate Endpoint (SUR): Plasma ammonia
Study 12053584 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 12053584 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 8697157 — Surrogate Endpoint (SUR): Blood pressure
Study 24477097 — Surrogate Endpoint (SUR): Blood pressure
Study 23084676 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 18510645 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19817641 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19817641 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol