TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11071181 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 9011485 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 9011485 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 22318095 — Surrogate Endpoint (SUR): Bone mineral density
Study 28085888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28085888 — Predictive Biomarker (PRD): PLA2G7 mRNA
Genes: PLA2G7; PAFAH
Study 28085888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28085888 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 25855898 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 23977178 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 19516120 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21718775 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 21718775 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21718775 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18640386 — Predictive Biomarker (PRD): AIP mRNA
Genes: AIP; XAP2
Study 18640386 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18640386 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16595206 — Surrogate Endpoint (SUR): Bone mineral density
Study 11874941 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9428817 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8608061 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31694152 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 16490627 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16490627 — Surrogate Endpoint (SUR): Blood pressure
Study 27639819 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18653654 — Surrogate Endpoint (SUR): Blood pressure
Study 29868833 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2399915 — Surrogate Endpoint (SUR): Serum creatinine
Study 17992118 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 390528 — Surrogate Endpoint (SUR): Blood pressure
Study 25781440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 23872799 — Surrogate Endpoint (SUR): Bone mineral density
Study 15106798 — Surrogate Endpoint (SUR): Blood pressure
Study 25191967 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 20584541 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 17368623 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 15135698 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9142342 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 28903476 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21691281 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 10752495 — Surrogate Endpoint (SUR): Serum creatinine
Study 21968596 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 30927000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30927000 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28384675 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 26138423 — Surrogate Endpoint (SUR): Blood pressure
Study 15896827 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 31323455 — Surrogate Endpoint (SUR): Blood pressure
Study 27939227 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27939227 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26186450 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17658455 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 17658455 — Surrogate Endpoint (SUR): Blood pressure
Study 21464158 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 21464158 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21464158 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 21464158 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26338095 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 26338095 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 21944671 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26400845 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 8597006 — Surrogate Endpoint (SUR): Serum creatinine
Study 7156449 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 12201932 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 12201932 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 7649315 — Surrogate Endpoint (SUR): Blood pressure
Study 21369950 — Surrogate Endpoint (SUR): Blood pressure
Study 25261882 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25261882 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28555208 — Surrogate Endpoint (SUR): Probing pocket depth
Study 10920316 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31309643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31309643 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30355140 — Surrogate Endpoint (SUR): Blood pressure
Study 22172502 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 2376838 — Surrogate Endpoint (SUR): Blood pressure
Study 29465293 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9736235 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 27766928 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27766928 — Predictive Biomarker (PRD): SLC4A7 mRNA
Genes: SLC4A7; BT; NBC2; NBC2B; NBC3; NBCn1; SBC2; SLC4A6
Study 18667247 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18667247 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 16556892 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 16556892 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17403074 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 3757441 — Surrogate Endpoint (SUR): Blood pressure
Study 20470796 — Predictive Biomarker (PRD): TNFRSF18 mRNA
Genes: TNFRSF18; AITR; GITR; UNQ319/PRO364
Study 20470796 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20470796 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 20470796 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20470796 — Predictive Biomarker (PRD): CCL18 mRNA
Genes: CCL18; AMAC1; DCCK1; MIP4; PARC; SCYA18
Study 20470796 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 20470796 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15030303 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8867568 — Surrogate Endpoint (SUR): Blood pressure
Study 17972024 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 10794751 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 29893893 — Monitoring Biomarker (MOI): HBV DNA
Study 12085859 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study 8697064 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 8697064 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 8697064 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 8697064 — Surrogate Endpoint (SUR): Blood pressure
Study 14750044 — Surrogate Endpoint (SUR): Blood pressure
Study 31883339 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30301734 — Surrogate Endpoint (SUR): Bone mineral density
Study 25510770 — Surrogate Endpoint (SUR): Blood pressure
Study 16529048 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 10978851 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8818086 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18947396 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 21443986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21443986 — Surrogate Endpoint (SUR): Blood pressure
Study 21443986 — Surrogate Endpoint (SUR): Serum creatinine
Study 21443986 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21443986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19577483 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9583728 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 9583728 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 31045789 — Surrogate Endpoint (SUR): Blood pressure
Study 26573217 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 15744332 — Surrogate Endpoint (SUR): Blood pressure
Study 2651951 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 31596110 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 8783218 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31902373 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 24673044 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 22337561 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study 9097709 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 19949848 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16606646 — Safety Biomarker (SAF): Human leucocyte antigen
Study 15005736 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15005736 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 9100038 — Surrogate Endpoint (SUR): Blood pressure
Study 18437172 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 18437172 — Predictive Biomarker (PRD): PAX8 mRNA
Genes: PAX8
Study 28906205 — Surrogate Endpoint (SUR): Blood pressure
Study 20488469 — Safety Biomarker (SAF): Hyaluronic acid
Study 12436050 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9179553 — Surrogate Endpoint (SUR): Blood pressure
Study 2950359 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31486272 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study 25965624 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 25965624 — Safety Biomarker (SAF): Hepatitis A virus cellular receptor 1
Genes: HAVCR1; KIM1; TIM1; TIMD1
Study 25965624 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 25965624 — Surrogate Endpoint (SUR): Serum creatinine
Study 16766279 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16766279 — Surrogate Endpoint (SUR): Blood pressure
Study 12585341 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 12585341 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 9179087 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17239698 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17239698 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17239698 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9578503 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31141730 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 15330271 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 15330271 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27008910 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 27008910 — Predictive Biomarker (PRD): TRAPPC9 mRNA
Genes: TRAPPC9; KIAA1882; NIBP; T1
Study 27008910 — Predictive Biomarker (PRD): RANGAP1 mRNA
Genes: RANGAP1; KIAA1835; SD
Study 24613825 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18378563 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 24424357 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16455634 — Surrogate Endpoint (SUR): Serum creatinine
Study 31932569 — Surrogate Endpoint (SUR): Blood pressure
Study 31932569 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29385178 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 25242204 — Predictive Biomarker (PRD): SLC23A2 mRNA
Genes: SLC23A2; KIAA0238; NBTL1; SLC23A1; SVCT2; YSPL2
Study 22897461 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22897461 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22897461 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17033631 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 15875240 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 9607691 — Surrogate Endpoint (SUR): Blood pressure
Study 1965645 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 25818379 — Predictive Biomarker (PRD): WTIP mRNA
Genes: WTIP
Study 12629429 — Surrogate Endpoint (SUR): Blood pressure
Study 3702214 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31589971 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 31589971 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 20833992 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20833992 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11019371 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11019371 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 18719041 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 25330012 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 25330012 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20401474 — Surrogate Endpoint (SUR): Blood pressure
Study 20401474 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 9121505 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 25600198 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21862744 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30543311 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 28254099 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 25945013 — Predictive Biomarker (PRD): OCLN mRNA
Genes: OCLN
Study 22162138 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30028245 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27020488 — Surrogate Endpoint (SUR): Blood pressure
Study 20617290 — Surrogate Endpoint (SUR): Bone mineral density
Study 20617290 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23235141 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 21084039 — Safety Biomarker (SAF): Interleukin 12
Study 16417078 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16417078 — Surrogate Endpoint (SUR): Bone mineral density
Study 1881997 — Surrogate Endpoint (SUR): Blood pressure
Study 3929584 — Surrogate Endpoint (SUR): Blood pressure
Study 20185012 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30704890 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30704890 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30704890 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11893230 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11893230 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10386279 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8610952 — Surrogate Endpoint (SUR): Blood pressure
Study 28296732 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28296732 — Surrogate Endpoint (SUR): Blood pressure
Study 26567274 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 17878762 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31958656 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31958656 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31958656 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22505055 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22505055 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18682000 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18682000 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16284236 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 3083519 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3083519 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 3083519 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 14555296 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9069293 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 8450178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8450178 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 29073916 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 21480950 — Surrogate Endpoint (SUR): Blood pressure
Study 8724298 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23198915 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16290894 — Predictive Biomarker (PRD): BNC1 mRNA
Genes: BNC1; BNC
Study 16290894 — Surrogate Endpoint (SUR): Blood pressure
Study 29172715 — Surrogate Endpoint (SUR): Blood pressure
Study 22551811 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22551811 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22551811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11808836 — Surrogate Endpoint (SUR): Blood pressure
Study 24129964 — Predictive Biomarker (PRD): RB1
Genes: RB; PPP1R130
Study 16398436 — Surrogate Endpoint (SUR): Bone mineral density
Study 21530095 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 21530095 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18505442 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 18505442 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 29079460 — Pharmacodynamic Biomarker (PDY): Auditory steady-state response
Study 22357739 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11407289 — Surrogate Endpoint (SUR): Blood pressure
Study 28134330 — Predictive Biomarker (PRD): APOA5 mRNA
Genes: APOA5; RAP3; UNQ411/PRO773
Study 23124598 — Safety Biomarker (SAF): miR-30e
Genes: MIR30E
Study 18477276 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 8087930 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 8087930 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 25405570 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25405570 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25405570 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 23233662 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 16968805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16968805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26956025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26956025 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26956025 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26956025 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30418528 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11281499 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2870722 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24001888 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24163957 — Surrogate Endpoint (SUR): Serum triglycerides
Study 10935667 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 24865417 — Safety Biomarker (SAF): BDNF
Study 28230324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28230324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12495832 — Surrogate Endpoint (SUR): Blood pressure