TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21565740 — Predictive Biomarker (PRD): IGF2R mRNA
Genes: IGF2R; MPRI
Study 16490909 — Surrogate Endpoint (SUR): Bone mineral density
Study 31343550 — Surrogate Endpoint (SUR): Blood pressure
Study 24716680 — Surrogate Endpoint (SUR): Serum creatinine
Study 23963688 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20092710 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17804564 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17804564 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 15617454 — Surrogate Endpoint (SUR): Blood pressure
Study 25677122 — Predictive Biomarker (PRD): LARS1 mRNA
Genes: LARS1; KIAA1352; LARS
Study 23592128 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8659773 — Surrogate Endpoint (SUR): Blood pressure
Study 2024848 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 24411480 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 15471616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15471616 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9660522 — Surrogate Endpoint (SUR): Blood pressure
Study 26375288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16600647 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 8118746 — Surrogate Endpoint (SUR): Bone mineral density
Study 8118746 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 22258209 — Surrogate Endpoint (SUR): Blood pressure
Study 22258209 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20946333 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20946333 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16822823 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 16822823 — Safety Biomarker (SAF): Peroxisome proliferator-activated receptor alpha
Genes: PPARA
Study 11090798 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8923865 — Surrogate Endpoint (SUR): Blood pressure
Study 27523046 — Surrogate Endpoint (SUR): Probing pocket depth
Study 15705982 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10603730 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 30967649 — Predictive Biomarker (PRD): Hormone receptor
Study 30232642 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 30232642 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30232642 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27902713 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27902713 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 8892171 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12404190 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 12404190 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 21526339 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 21526339 — Surrogate Endpoint (SUR): Blood pressure
Study 2535052 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2535052 — Surrogate Endpoint (SUR): Blood pressure
Study 17550932 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3139830 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 3139830 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 26096691 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 18433307 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 14611708 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 14611708 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 11938802 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 26247163 — Predictive Biomarker (PRD): NES mRNA
Genes: NES; Nbla00170
Study 26247163 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 26247163 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 20581391 — Surrogate Endpoint (SUR): Total kidney volume
Study 10848884 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27085221 — Surrogate Endpoint (SUR): Blood pressure
Study 8042098 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31221002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16618363 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 24685604 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24685604 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11090788 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11090788 — Surrogate Endpoint (SUR): Blood pressure
Study 20491360 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11835037 — Surrogate Endpoint (SUR): Blood pressure
Study 12523874 — Predictive Biomarker (PRD): NE
Study 29173603 — Surrogate Endpoint (SUR): Blood pressure
Study 14555261 — Surrogate Endpoint (SUR): Bone mineral density
Study 31685212 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 31685212 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31685212 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16195034 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12012138 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 7557813 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 2149728 — Surrogate Endpoint (SUR): Blood pressure
Study 31445061 — Surrogate Endpoint (SUR): Blood pressure
Study 17186282 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 24183981 — Predictive Biomarker (PRD): IVNS1ABP mRNA
Genes: IVNS1ABP; ARA3; FLARA3; KIAA0850; KLHL39; NS1; NS1BP; HSPC068
Study 12379622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9579768 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9579768 — Surrogate Endpoint (SUR): Blood pressure
Study 7543956 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28244612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28244612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28244612 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10202747 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 24218041 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24218041 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 24218041 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 24218041 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17252567 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 23373541 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17302058 — Surrogate Endpoint (SUR): Blood pressure
Study 12765886 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 12765886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12765886 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8675231 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24975366 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 11208843 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 28272164 — Surrogate Endpoint (SUR): Bone mineral density
Study 19286582 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19286582 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10451042 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 8665993 — Surrogate Endpoint (SUR): Blood pressure
Study 22215335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22215335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22215335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 4091997 — Surrogate Endpoint (SUR): Blood pressure
Study 30813546 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19215336 — Monitoring Biomarker (MOI): HBV DNA
Study 17270090 — Surrogate Endpoint (SUR): Serum creatinine
Study 17270090 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 14709952 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 8112372 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26406397 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26406397 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 14654535 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 14654535 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 1589555 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 3896595 — Surrogate Endpoint (SUR): Blood pressure
Study 26732017 — Surrogate Endpoint (SUR): Blood pressure
Study 23460233 — Predictive Biomarker (PRD): Liver iron
Study 18403668 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 18403668 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18403668 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17488461 — Surrogate Endpoint (SUR): Blood pressure
Study 17488461 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 11897280 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 31841026 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 26095142 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24125150 — Predictive Biomarker (PRD): ARID3B mRNA
Genes: ARID3B; BDP; DRIL2
Study 1785707 — Surrogate Endpoint (SUR): Blood pressure
Study 28422864 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 28422864 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24797262 — Monitoring Biomarker (MOI): HBV DNA
Study 22633079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22633079 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 1567626 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19948872 — Surrogate Endpoint (SUR): Serum creatinine
Study 8645892 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8645892 — Surrogate Endpoint (SUR): Serum creatinine
Study 1698429 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 1698429 — Surrogate Endpoint (SUR): Blood pressure
Study 24331773 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 7871107 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23601333 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28758951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26040352 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15482074 — Predictive Biomarker (PRD): POLE mRNA
Genes: POLE; POLE1
Study 21450115 — Predictive Biomarker (PRD): SELENOP mRNA
Genes: SELENOP; SELP; SEPP1
Study 9773794 — Surrogate Endpoint (SUR): Serum potassium
Study 22858814 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11987981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2691131 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2691131 — Surrogate Endpoint (SUR): Blood pressure
Study 2691131 — Surrogate Endpoint (SUR): Serum potassium
Study 10916106 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20237063 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 18537187 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 18537187 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 18537187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18537187 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15893176 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 15893176 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10971545 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 22889573 — Surrogate Endpoint (SUR): Blood pressure
Study 20179126 — Surrogate Endpoint (SUR): Blood pressure
Study 20179126 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31366053 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 31366053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31366053 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31366053 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 31366053 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31366053 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 26503312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27699493 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 27699493 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27699493 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 25367150 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23543666 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 20023348 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 20023348 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 17264975 — Surrogate Endpoint (SUR): Bone mineral density
Study 14984920 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 11686810 — Surrogate Endpoint (SUR): Probing pocket depth
Study 29803341 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29715303 — Surrogate Endpoint (SUR): Blood pressure
Study 8768849 — Predictive Biomarker (PRD): PZP mRNA
Genes: PZP; CPAMD6
Study 8768849 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 6637785 — Surrogate Endpoint (SUR): Blood pressure
Study 25922614 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 17538537 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 16842478 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 16842478 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29858911 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 29858911 — Surrogate Endpoint (SUR): Blood pressure
Study 18003811 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16575382 — Surrogate Endpoint (SUR): Blood pressure
Study 17198647 — Surrogate Endpoint (SUR): Blood pressure
Study 10910446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10910446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 4093974 — Surrogate Endpoint (SUR): Blood pressure
Study 31433997 — Predictive Biomarker (PRD): ITFG1 mRNA
Genes: ITFG1; LNKN-1; TIP; CDA08
Study 11126523 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18444145 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 12704501 — Surrogate Endpoint (SUR): Blood pressure
Study 27152849 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 17912164 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 12045167 — Surrogate Endpoint (SUR): Serum uric acid
Study 10073079 — Surrogate Endpoint (SUR): Blood pressure
Study 24095220 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17566313 — Surrogate Endpoint (SUR): Blood pressure
Study 12911367 — Surrogate Endpoint (SUR): Blood pressure
Study 2887192 — Surrogate Endpoint (SUR): Serum potassium
Study 12686409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12686409 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 12686409 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12686409 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11078264 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 25091714 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17984125 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17984125 — Predictive Biomarker (PRD): TMPRSS13 mRNA
Genes: TMPRSS13; MSP; TMPRSS11
Study 27576846 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 27576846 — Predictive Biomarker (PRD): MDM2
Genes: HDM2; MGC5370
Study 27576846 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 27576846 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study 20151996 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 20151996 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 12855261 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 2289410 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2289410 — Surrogate Endpoint (SUR): Blood pressure
Study 31152468 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24916951 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24370303 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24370303 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2682474 — Surrogate Endpoint (SUR): Blood pressure
Study 12543892 — Surrogate Endpoint (SUR): Blood pressure
Study 8011251 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20843978 — Surrogate Endpoint (SUR): Blood pressure
Study 10871576 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 23752057 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 6414387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30975599 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28327526 — Predictive Biomarker (PRD): NAIP mRNA
Genes: NAIP; BIRC1
Study 9233719 — Surrogate Endpoint (SUR): Serum creatinine
Study 2828818 — Surrogate Endpoint (SUR): Blood pressure
Study 28591764 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 14642682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14642682 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 14642682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8977984 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 6204148 — Surrogate Endpoint (SUR): Blood pressure
Study 6204148 — Surrogate Endpoint (SUR): Serum potassium
Study 19809363 — Surrogate Endpoint (SUR): Blood pressure
Study 14706762 — Surrogate Endpoint (SUR): Bone mineral density
Study 9926278 — Surrogate Endpoint (SUR): Blood pressure
Study 23115341 — Surrogate Endpoint (SUR): Blood pressure
Study 26948962 — Surrogate Endpoint (SUR): Blood pressure
Study 20073212 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 15259516 — Surrogate Endpoint (SUR): Blood pressure
Study 2591060 — Predictive Biomarker (PRD): SMS mRNA
Genes: SMS
Study 2591060 — Surrogate Endpoint (SUR): Blood pressure
Study 31833226 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 11777191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 4149613 — Surrogate Endpoint (SUR): Blood pressure
Study 21526412 — Surrogate Endpoint (SUR): Blood pressure
Study 16505284 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3095503 — Surrogate Endpoint (SUR): Serum creatinine
Study 23995299 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 22935338 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22935338 — Surrogate Endpoint (SUR): Blood pressure
Study 22935338 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 16164158 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 9538650 — Predictive Biomarker (PRD): ATP7B mRNA
Genes: ATP7B; PWD; WC1; WND
Study 8251842 — Surrogate Endpoint (SUR): Blood pressure