TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17214933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 991103 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 30998121 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 28969431 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27861335 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 27861335 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17596121 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 388398 — Surrogate Endpoint (SUR): Serum uric acid
Study 16900233 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15039494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11731186 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11731186 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11731186 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 3815764 — Surrogate Endpoint (SUR): Blood pressure
Study 15893181 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15893181 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12668787 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 30126064 — Predictive Biomarker (PRD): ACTG1 mRNA
Genes: ACTG1; ACTG
Study 30126064 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study 28106354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25582310 — Surrogate Endpoint (SUR): Serum calcium
Study 24016068 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 30304656 — Surrogate Endpoint (SUR): Serum creatinine
Study 17017821 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 12705366 — Surrogate Endpoint (SUR): Bone mineral density
Study 31043758 — Surrogate Endpoint (SUR): Blood pressure
Study 3747800 — Surrogate Endpoint (SUR): Forced vital capacity
Study 27499378 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 18380954 — Surrogate Endpoint (SUR): Bone mineral density
Study 2197297 — Surrogate Endpoint (SUR): Blood pressure
Study 15273192 — Surrogate Endpoint (SUR): Serum sodium
Study 10396713 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study 7747715 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2174950 — Surrogate Endpoint (SUR): Blood pressure
Study 6769256 — Surrogate Endpoint (SUR): Blood pressure
Study 29775437 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 24612081 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24612081 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15676171 — Surrogate Endpoint (SUR): Blood pressure
Study 28406125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28406125 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9227205 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19214743 — Surrogate Endpoint (SUR): Bone mineral density
Study 12586255 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12586255 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10589275 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17701671 — Surrogate Endpoint (SUR): Blood pressure
Study 27681753 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 18946896 — Surrogate Endpoint (SUR): Serum creatinine
Study 31852125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26266414 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study 21617197 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 21617197 — Surrogate Endpoint (SUR): Blood pressure
Study 21617197 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21617197 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 14510339 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 3533371 — Surrogate Endpoint (SUR): Blood pressure
Study 29385034 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15356075 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 15356075 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8450399 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21901480 — Surrogate Endpoint (SUR): Bone mineral density
Study 15023882 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 11135381 — Surrogate Endpoint (SUR): Blood pressure
Study 10399517 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10399517 — Surrogate Endpoint (SUR): Blood pressure
Study 7771954 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23512062 — Predictive Biomarker (PRD): LY96 mRNA
Genes: LY96; ESOP1; MD2
Study 23512062 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 22283900 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2455187 — Surrogate Endpoint (SUR): Blood pressure
Study 8372519 — Safety Biomarker (SAF): BCHE
Genes: E1
Study 28919201 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25976467 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 25976467 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 25976467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25976467 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25976467 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16402081 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 16402081 — Predictive Biomarker (PRD); Safety Biomarker (SAF): NCS1 mRNA
Genes: NCS1; FLUP; FREQ
Study 16402081 — Safety Biomarker (SAF): DRD2
Study 8398218 — Surrogate Endpoint (SUR): Blood pressure
Study 8398218 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31852268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31852268 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27856142 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30712901 — Safety Biomarker (SAF): Hyaluronic acid
Study 27111542 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 21985070 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 30658660 — Predictive Biomarker (PRD): BMF mRNA
Genes: BMF
Study 30658660 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 30658660 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 11708574 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11708574 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30688979 — Surrogate Endpoint (SUR): Blood pressure
Study 27703563 — Surrogate Endpoint (SUR): Blood pressure
Study 17898947 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 17898947 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17898947 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15180973 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29924240 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 25557189 — Safety Biomarker (SAF): IL-6 and IL-10
Study 21541732 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 14675064 — Surrogate Endpoint (SUR): Bone mineral density
Study 14675064 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 27185685 — Surrogate Endpoint (SUR): Blood pressure
Study 22157880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20301021 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17243915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17243915 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 17243915 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17243915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17243915 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9889429 — Surrogate Endpoint (SUR): Blood pressure
Study 27484763 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25807090 — Surrogate Endpoint (SUR): Serum uric acid
Study 9649985 — Surrogate Endpoint (SUR): Blood pressure
Study 2524386 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 11519700 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 11519700 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 27484507 — Surrogate Endpoint (SUR): Blood pressure
Study 20022990 — Surrogate Endpoint (SUR): Bone mineral density
Study 19246793 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 10715305 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 30497530 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30497530 — Predictive Biomarker (PRD): TMEM100 mRNA
Genes: TMEM100
Study 30497530 — Predictive Biomarker (PRD): ALK
Genes: CD246; ALK1
Study 30497530 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16113791 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16113791 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 17237646 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8848889 — Surrogate Endpoint (SUR): Blood pressure
Study 31752042 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 30730541 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28831241 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28831241 — Surrogate Endpoint (SUR): Blood pressure
Study 30535716 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 21183370 — Predictive Biomarker (PRD): SV2A mRNA
Genes: SV2A; KIAA0736; PSEC0174
Study 19859541 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 9678778 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 19122109 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19122109 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17406886 — Surrogate Endpoint (SUR): Blood pressure
Study 7641661 — Surrogate Endpoint (SUR): Blood pressure
Study 26712187 — Surrogate Endpoint (SUR): Blood pressure
Study 26712187 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24024499 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 24024499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24024499 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24024499 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11846843 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7138753 — Surrogate Endpoint (SUR): Blood pressure
Study 31268130 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 31268130 — Predictive Biomarker (PRD): Microsatellite instability
Study 24420556 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 17312209 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 15353025 — Surrogate Endpoint (SUR): Blood pressure
Study 3221375 — Surrogate Endpoint (SUR): Blood pressure
Study 17001471 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9122013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9122013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 6615664 — Surrogate Endpoint (SUR): Blood pressure
Study 6615664 — Surrogate Endpoint (SUR): Serum potassium
Study 16950948 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 11374008 — Surrogate Endpoint (SUR): Blood pressure
Study 25621429 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 20195575 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 26564024 — Surrogate Endpoint (SUR): Serum calcium
Study 24995191 — Surrogate Endpoint (SUR): Blood pressure
Study 17013567 — Surrogate Endpoint (SUR): Serum creatinine
Study 17013567 — Surrogate Endpoint (SUR): Bone mineral density
Study 17013567 — Surrogate Endpoint (SUR): Serum calcium
Study 15823826 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 10064759 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2318517 — Surrogate Endpoint (SUR): Blood pressure
Study 2318517 — Surrogate Endpoint (SUR): Serum potassium
Study 20162528 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20162528 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20162528 — Safety Biomarker (SAF): Interleukin 1
Study 20162528 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18219179 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18219179 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11391125 — Safety Biomarker (SAF): DRD2
Study 9886725 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26025798 — Surrogate Endpoint (SUR): Blood pressure
Study 22157768 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 31583921 — Surrogate Endpoint (SUR): Bone mineral density
Study 25773009 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 7798544 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 30424796 — Monitoring Biomarker (MOI): Procalcitonin
Study 24723220 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 20842069 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12589712 — Predictive Biomarker (PRD): IGF2R mRNA
Genes: IGF2R; MPRI
Study 1683249 — Surrogate Endpoint (SUR): Blood pressure
Study 10364784 — Surrogate Endpoint (SUR): Serum creatinine
Study 24133059 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 22493101 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 19070025 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 16335907 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 11995344 — Predictive Biomarker (PRD): GPT mRNA
Genes: GPT; AAT1; GPT1
Study 9701620 — Surrogate Endpoint (SUR): Bone mineral density
Study 1898841 — Surrogate Endpoint (SUR): Blood pressure
Study 27492324 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27492324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 27492324 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27492324 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 19171951 — Surrogate Endpoint (SUR): Blood pressure
Study 17224709 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 2059591 — Surrogate Endpoint (SUR): Blood pressure
Study 26806917 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 19647623 — Predictive Biomarker (PRD): CD22 mRNA
Genes: CD22; SIGLEC2
Study 19647623 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 19647623 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17721395 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17721395 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31826360 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31826360 — Predictive Biomarker (PRD): Hormone receptor
Study 31323516 — Predictive Biomarker (PRD): HAL mRNA
Genes: HAL; HIS
Study 25193390 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 23470209 — Safety Biomarker (SAF): Hyaluronic acid
Study 16837920 — Surrogate Endpoint (SUR): Serum calcium
Study 10951511 — Surrogate Endpoint (SUR): Bone mineral density
Study 29853660 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 29853660 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 29853660 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 29853660 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 29853660 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 29853660 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27193748 — Surrogate Endpoint (SUR): Bone mineral density
Study 24525316 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20399945 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1773423 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 31675175 — Predictive Biomarker (PRD): PSD4 mRNA
Genes: PSD4; EFA6B; TIC
Study 11996608 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11996608 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23958252 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 23958252 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23958252 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23958252 — Surrogate Endpoint (SUR): Blood pressure
Study 17284629 — Surrogate Endpoint (SUR): Serum calcium
Study 17284629 — Surrogate Endpoint (SUR): Bone mineral density
Study 17284629 — Surrogate Endpoint (SUR): Blood pressure
Study 3311648 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25545821 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16816481 — Surrogate Endpoint (SUR): Bone mineral density
Study 11035314 — Surrogate Endpoint (SUR): Blood pressure
Study 1454160 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 11135227 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 11135227 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11135227 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 11135227 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): FasL mRNA
Genes: FASLG; APT1LG1; CD95L; FASL; TNFSF6
Study 20087377 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10381910 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 29676592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29676592 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29676592 — Predictive Biomarker (PRD): CXCR3 mRNA
Genes: CXCR3; GPR9
Study 28573748 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 18046594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18046594 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 8614301 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8614301 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23565815 — Surrogate Endpoint (SUR): Blood pressure
Study 23565815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23565815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15201559 — Surrogate Endpoint (SUR): Blood pressure
Study 3270664 — Surrogate Endpoint (SUR): Probing pocket depth
Study 27004411 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 27004411 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 23528159 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18584876 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 11821454 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study 29023829 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 16925285 — Surrogate Endpoint (SUR): Blood pressure
Study 8605592 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22849580 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22849580 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20417879 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18683667 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 15911947 — Surrogate Endpoint (SUR): Blood pressure
Study 10574596 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 10574596 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 10574596 — Predictive Biomarker (PRD): CD44 mRNA
Genes: CD44; LHR; MDU2; MDU3; MIC4
Study 10574596 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 10574596 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12837046 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12837046 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol