TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00118794 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT01124474 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04508985 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00712049 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00712049 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00326521 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00661219 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03761966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03761966 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03648970 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT03808454 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03808454 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03808454 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00005271 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02992834 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00005940 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT03123588 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01608204 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT04767412 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT01116843 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00949663 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03786575 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04429594 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03122366 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT01716156 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT00404300 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT04685720 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT02282033 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03094832 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT03106779 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT03106779 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02192697 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02192697 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01543503 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02460380 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02460380 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00324194 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT01196234 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01196234 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04082702 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03116815 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03593447 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT04253860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04253860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02496117 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04279600 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study NCT04279600 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT02744547 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT02744547 — Predictive Biomarker (PRD): Liver iron
Study NCT00968968 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01252641 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT01252641 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04845971 — Predictive Biomarker (PRD): MAF mRNA
Genes: MAF
Study NCT04845971 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04845971 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01090206 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00127933 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03093168 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT05250154 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study NCT05250154 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study NCT01112007 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03043469 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT01735799 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01735799 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study NCT01137721 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study NCT00469027 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02017613 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT04652843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04652843 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study NCT04652843 — Pharmacodynamic Biomarker (PDY): Synuclein alpha
Genes: SNCA; NACP; PARK1
Study NCT03367585 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01108796 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04480931 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03521336 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT03483090 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study NCT02145663 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study NCT01037465 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT04518423 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02251678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02251678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05028595 — Predictive Biomarker (PRD): Liver iron
Study NCT00363467 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04359719 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT03055221 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT03410537 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study NCT04371835 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04461535 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT01881295 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03864562 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT03843970 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01972971 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT01972971 — Predictive Biomarker (PRD): VKORC1 mRNA
Genes: VKORC1; VKOR; MSTP134; MSTP576; UNQ308/PRO351
Study NCT02475057 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT03360487 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT02277860 — Pharmacodynamic Biomarker (PDY): Nasal potential difference
Study NCT04376632 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04247035 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03473301 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02959892 — Predictive Biomarker (PRD): AMPH mRNA
Genes: AMPH; AMPH1
Study NCT02211742 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT00281580 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02919345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02919345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02919345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02919345 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT02919345 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT02919345 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02919345 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study NCT02919345 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT02786511 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT00225758 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00225758 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00049218 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT01327781 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT05834335 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00507507 — Monitoring Biomarker (MOI): HBV DNA
Study NCT00158470 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01524458 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT00375310 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT00375310 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00375310 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01924156 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT02737787 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT03158597 — Predictive Biomarker (PRD): TDO2 mRNA
Genes: TDO2; TDO
Study NCT02547987 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04333654 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02173366 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01829503 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02507999 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02325895 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03934307 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Angiotensinogen
Genes: AGT; SERPINA8
Study NCT00451984 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01824147 — Safety Biomarker (SAF): Argininosuccinate synthase
Genes: ASS1; ASS
Study NCT03693508 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03358706 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT03358706 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT03358706 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03358706 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT03358706 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT04201405 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04201405 — Predictive Biomarker (PRD): SGSH mRNA
Genes: SGSH; HSS
Study NCT04846257 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04846257 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04063137 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04462393 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00362323 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT00025233 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02926612 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study NCT00452400 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02345577 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02410174 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00051129 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT00185055 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT00185055 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01566201 — Safety Biomarker (SAF): Interleukin 1
Study NCT03919266 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT03919266 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT00060385 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT01429610 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02402712 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01663805 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study NCT00437775 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00072579 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03280030 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT01939275 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03799367 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00768859 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03549260 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03986541 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03986541 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04197960 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04398914 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04398914 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03439514 — Predictive Biomarker (PRD): LMNA mRNA
Genes: LMNA; LMN1
Study NCT00326495 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00326495 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00326495 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00326495 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT00326495 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00326495 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00326495 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00684736 — Predictive Biomarker (PRD): Indoleamine 2,3-dioxygenase 1
Genes: IDO1; IDO; INDO
Study NCT03197935 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03278145 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study NCT03278145 — Safety Biomarker (SAF): Netrin-1
Genes: NTN1; NTN1L
Study NCT02549378 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04172701 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study NCT04117568 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04117568 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT00509600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00509600 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT01239745 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01237028 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT03686696 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02758223 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study NCT01769469 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02615067 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT03708289 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02174783 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01745302 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01210911 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT01210911 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT01210911 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01210911 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03949231 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03949231 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03949231 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT02249793 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00532857 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00172666 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04031768 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01755312 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02639559 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT05893667 — Predictive Biomarker (PRD): CCL20 mRNA
Genes: CCL20; LARC; MIP3A; SCYA20
Study NCT01604031 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT01604031 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT04614779 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04614779 — Predictive Biomarker (PRD): Liver iron
Study NCT00416754 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT00416754 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03591536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03591536 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03591536 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01634750 — Predictive Biomarker (PRD): GNE mRNA
Genes: GNE; GLCNE
Study NCT04319419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04319419 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04319419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04319419 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT04319419 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT03847090 — Surrogate Endpoint (SUR): Urinary oxalate
Study NCT01447472 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01447472 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT01447472 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT01447472 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT01447472 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SLC6A4 mRNA
Genes: SLC6A4; HTT; SERT
Study NCT04275414 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04275414 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01815580 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT00513864 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02375269 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00305279 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT00001082 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01307618 — Safety Biomarker (SAF): Interleukin 12
Study NCT03075735 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03075735 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT03075735 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study NCT03701646 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03891394 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT03361072 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study NCT03134638 — Predictive Biomarker (PRD): CDK7 mRNA
Genes: CDK7; CAK; CAK1; CDKN7; MO15; STK1
Study NCT00736476 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT00552500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00147537 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT00739219 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00111930 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00522574 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT00535197 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00861679 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11