TrialPanorama/TrialPanorama-database huggingface dataset:
Study 20513982 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 28416247 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 30172428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3521524 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28566124 — Safety Biomarker (SAF): Reactive oxygen species
Study 10895973 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 29641669 — Surrogate Endpoint (SUR): Blood pressure
Study 9193431 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 19446147 — Monitoring Biomarker (MOI): HBV DNA
Study 18631345 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 11822926 — Surrogate Endpoint (SUR): Serum creatinine
Study 6945060 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 28260863 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 28260863 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 23676106 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23676106 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20361714 — Surrogate Endpoint (SUR): Blood pressure
Study 17234798 — Surrogate Endpoint (SUR): Blood pressure
Study 7699618 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3129807 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 3129807 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 3129807 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 28993287 — Surrogate Endpoint (SUR): Blood pressure
Study 26957281 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26957281 — Surrogate Endpoint (SUR): Serum uric acid
Study 26434249 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23552120 — Surrogate Endpoint (SUR): Blood pressure
Study 24843534 — Surrogate Endpoint (SUR): Blood pressure
Study 24843534 — Surrogate Endpoint (SUR): Serum uric acid
Study 24843534 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10232493 — Surrogate Endpoint (SUR): Blood pressure
Study 18936231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18936231 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 11310904 — Surrogate Endpoint (SUR): Serum creatinine
Study 8612407 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8612407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8612407 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1348620 — Surrogate Endpoint (SUR): Blood pressure
Study 29264780 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 26592200 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24645671 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 13129479 — Surrogate Endpoint (SUR): Blood pressure
Study 20693148 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 3312502 — Surrogate Endpoint (SUR): Blood pressure
Study 21823276 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 21823276 — Surrogate Endpoint (SUR): Blood pressure
Study 17876407 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 17876407 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 2548660 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2548660 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26077235 — Predictive Biomarker (PRD): Hormone receptor
Study 26077235 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23575450 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23575450 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19189403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19189403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11567048 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 11567048 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 11567048 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 11567048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11567048 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 9129016 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 20030546 — Surrogate Endpoint (SUR): Blood pressure
Study 10990237 — Surrogate Endpoint (SUR): Bone mineral density
Study 31962050 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 31255678 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 31255678 — Safety Biomarker (SAF): BDNF
Study 31255678 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23498848 — Predictive Biomarker (PRD): SYN1 mRNA
Genes: SYN1
Study 23682595 — Surrogate Endpoint (SUR): Blood pressure
Study 23682595 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21953540 — Predictive Biomarker (PRD): TNFRSF11A mRNA
Genes: TNFRSF11A; RANK
Study 21953540 — Surrogate Endpoint (SUR): Bone mineral density
Study 17211115 — Surrogate Endpoint (SUR): Blood pressure
Study 12845429 — Surrogate Endpoint (SUR): Serum potassium
Study 26227795 — Surrogate Endpoint (SUR): Blood pressure
Study 23744427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23744427 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 23744427 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23744427 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30513795 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 20445353 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11973494 — Surrogate Endpoint (SUR): Blood pressure
Study 24793536 — Surrogate Endpoint (SUR): Blood pressure
Study 24793536 — Surrogate Endpoint (SUR): Serum potassium
Study 7937384 — Surrogate Endpoint (SUR): Blood pressure
Study 31963808 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25076278 — Surrogate Endpoint (SUR): Blood pressure
Study 16686385 — Surrogate Endpoint (SUR): Blood pressure
Study 29668448 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 27333010 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 17564755 — Predictive Biomarker (PRD): OMD mRNA
Genes: OMD; SLRR2C; UNQ190/PRO216
Study 10607255 — Monitoring Biomarker (MOI): HBV DNA
Study 7829789 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21977863 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 9404431 — Surrogate Endpoint (SUR): Blood pressure
Study 30336337 — Surrogate Endpoint (SUR): Blood pressure
Study 30336337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30336337 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24667753 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24667753 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 22466383 — Surrogate Endpoint (SUR): Bone mineral density
Study 19194534 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 20524719 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20524719 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20524719 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20524719 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18581961 — Pharmacodynamic Biomarker (PDY): Human leukocyte antigen DR
Study 16463989 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 7565455 — Surrogate Endpoint (SUR): Bone mineral density
Study 27236602 — Predictive Biomarker (PRD): POR mRNA
Genes: POR; CYPOR
Study 24697948 — Predictive Biomarker (PRD): ARC mRNA
Genes: ARC; KIAA0278
Study 11680663 — Surrogate Endpoint (SUR): Serum creatinine
Study 31664441 — Surrogate Endpoint (SUR): Bone mineral density
Study 23062489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23062489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23062489 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 23062489 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23062489 — Safety Biomarker (SAF): IL-6 and IL-10
Study 18572351 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 12436372 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3988967 — Surrogate Endpoint (SUR): Blood pressure
Study 24763885 — Surrogate Endpoint (SUR): Blood pressure
Study 27613719 — Surrogate Endpoint (SUR): Bone mineral density
Study 26350550 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24156306 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 21335007 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 19352198 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 29579195 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 23539933 — Surrogate Endpoint (SUR): Blood pressure
Study 15892271 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15892271 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15892271 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 2258063 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 8420442 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8420442 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8420442 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20536518 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20536518 — Surrogate Endpoint (SUR): Blood pressure
Study 20536518 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29239988 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 29239988 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29239988 — Surrogate Endpoint (SUR): Plasma ammonia
Study 31652875 — Surrogate Endpoint (SUR): Serum uric acid
Study 19812445 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 15593395 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 15593395 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 15593395 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12730746 — Surrogate Endpoint (SUR): Bone mineral density
Study 2680843 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 16463847 — Predictive Biomarker (PRD): PCLO mRNA
Genes: PCLO; ACZ; KIAA0559
Study 7594443 — Surrogate Endpoint (SUR): Blood pressure
Study 7594443 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 23345623 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 18663500 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 18663500 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1335539 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8527690 — Surrogate Endpoint (SUR): Blood pressure
Study 30144887 — Surrogate Endpoint (SUR): Serum calcium
Study 24585900 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9829449 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26633571 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26633571 — Predictive Biomarker (PRD): Proliferation marker protein Ki-67
Genes: MKI67
Study 25272582 — Surrogate Endpoint (SUR): Bone mineral density
Study 22517399 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 12409967 — Surrogate Endpoint (SUR): Blood pressure
Study 11256901 — Surrogate Endpoint (SUR): Serum creatinine
Study 24836758 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 22402971 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1574768 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 1574768 — Predictive Biomarker (PRD): Hormone receptor
Study 10506854 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10506854 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 10506854 — Surrogate Endpoint (SUR): Blood pressure
Study 8947397 — Surrogate Endpoint (SUR): Serum creatinine
Study 1911676 — Surrogate Endpoint (SUR): Blood pressure
Study 6240831 — Surrogate Endpoint (SUR): Blood pressure
Study 6240831 — Surrogate Endpoint (SUR): Serum uric acid
Study 29941498 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17611310 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 24505102 — Predictive Biomarker (PRD): LSR mRNA
Genes: LSR; ILDR3; LISCH
Study 10460070 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10460070 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22541248 — Predictive Biomarker (PRD): Interleukin 4 receptor alpha
Genes: IL4R; IL4RA; 582J2.1
Study 31727675 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30835950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14501546 — Surrogate Endpoint (SUR): Blood pressure
Study 10391658 — Surrogate Endpoint (SUR): Blood pressure
Study 2000739 — Predictive Biomarker (PRD): SKIC2 mRNA
Genes: SKIC2; DDX13; SKI2W; SKIV2; SKIV2L; W
Study 8918277 — Surrogate Endpoint (SUR): Bone mineral density
Study 2011945 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2011945 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 2011945 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 2011945 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 2011945 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25137425 — Surrogate Endpoint (SUR): Serum triglycerides
Study 9797484 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9797484 — Surrogate Endpoint (SUR): Bone mineral density
Study 9797484 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25892016 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20034232 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 20034232 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 8205299 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8205299 — Surrogate Endpoint (SUR): Serum creatinine
Study 23490288 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23490288 — Surrogate Endpoint (SUR): Blood pressure
Study 17698328 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 15309547 — Safety Biomarker (SAF): Reactive oxygen species
Study 11145854 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8161479 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29991140 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 24798484 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 24798484 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 24798484 — Safety Biomarker (SAF): Bacterial beta-glucuronidase
Genes: uidA; gurA; gusA; b1617; JW1609
Study 1444724 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 1444724 — Surrogate Endpoint (SUR): Blood pressure
Study 29514721 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22569995 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 15808404 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 15808404 — Predictive Biomarker (PRD): GSTA1 mRNA
Genes: GSTA1
Study 15808404 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Nqo1 mRNA
Genes: NQO1; DIA4; NMOR1
Study 15808404 — Predictive Biomarker (PRD): SLC38A1 mRNA
Genes: SLC38A1; ATA1; NAT2; SAT1; SNAT1
Study 10511370 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 8758241 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 25669986 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25669986 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25669986 — Safety Biomarker (SAF): IL-6 and IL-10
Study 18510696 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 18510696 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31195354 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19398935 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17822820 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 15641045 — Surrogate Endpoint (SUR): Serum uric acid
Study 31261494 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 26470637 — Surrogate Endpoint (SUR): Bone mineral density
Study 8401500 — Predictive Biomarker (PRD): ZFY mRNA
Genes: ZFY
Study 29198060 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 1446958 — Surrogate Endpoint (SUR): Blood pressure
Study 18708731 — Predictive Biomarker (PRD): TAOK2 mRNA
Genes: TAOK2; KIAA0881; MAP3K17; PSK; PSK1; UNQ2971/PRO7431
Study 26490493 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 26490493 — Predictive Biomarker (PRD): HTRA1 mRNA
Genes: HTRA1; HTRA; PRSS11
Study 26490493 — Predictive Biomarker (PRD): C2 mRNA
Genes: C2
Study 26490493 — Predictive Biomarker (PRD): CFB mRNA
Genes: CFB; BF; BFD
Study 26490493 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 26490493 — Predictive Biomarker (PRD): COL8A1 mRNA
Genes: COL8A1; C3orf7
Study 26490493 — Predictive Biomarker (PRD): RAD51B mRNA
Genes: RAD51B; RAD51L1; REC2
Study 9291414 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 29793800 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29793800 — Surrogate Endpoint (SUR): Blood pressure
Study 26730183 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 26730183 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2297344 — Surrogate Endpoint (SUR): Blood pressure
Study 2297344 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2297344 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23929521 — Predictive Biomarker (PRD): SST mRNA
Genes: SST
Study 19628206 — Surrogate Endpoint (SUR): Blood pressure
Study 11678862 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 27582175 — Surrogate Endpoint (SUR): Blood pressure
Study 18975322 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18975322 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 16021197 — Predictive Biomarker (PRD): ALPI mRNA
Genes: ALPI
Study 17383818 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 12574184 — Surrogate Endpoint (SUR): Bone mineral density
Study 12574184 — Surrogate Endpoint (SUR): Serum calcium
Study 10477245 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 14506621 — Surrogate Endpoint (SUR): Blood pressure
Study 10385131 — Surrogate Endpoint (SUR): Blood pressure
Study 8895240 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 20537376 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27903520 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27903520 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20631407 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 20631407 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 16441928 — Surrogate Endpoint (SUR): Serum creatinine
Study 16441928 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16441928 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16511633 — Pharmacodynamic Biomarker (PDY): Cathepsin S
Genes: CTSS
Study 11127843 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11127843 — Surrogate Endpoint (SUR): Blood pressure
Study 3304473 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 20820456 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 8927235 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 8927235 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 20386325 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20386325 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 18672194 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 18672194 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1