TrialPanorama/TrialPanorama-database huggingface dataset:
Study 14744921 — Surrogate Endpoint (SUR): Blood pressure
Study 11799264 — Surrogate Endpoint (SUR): Blood pressure
Study 26167618 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29649996 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29649996 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20139430 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20139430 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18672532 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14625133 — Predictive Biomarker (PRD): NPL mRNA
Genes: NPL; C1orf13
Study 11106203 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 11106203 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24251744 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22992267 — Predictive Biomarker (PRD): A1CF mRNA
Genes: A1CF; ACF; ASP
Study 16192735 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 16192735 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16192735 — Predictive Biomarker (PRD): PLG mRNA
Genes: PLG
Study 16192735 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3513670 — Surrogate Endpoint (SUR): Blood pressure
Study 3513670 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31303349 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31303349 — Surrogate Endpoint (SUR): Serum creatinine
Study 1559334 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 29325289 — Monitoring Biomarker (MOI): HBV DNA
Study 23490224 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9146850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29212965 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27755389 — Surrogate Endpoint (SUR): Blood pressure
Study 16368192 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 14600517 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30180236 — Safety Biomarker (SAF): Hyaluronic acid
Study 27627073 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22687788 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 20091113 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 20091113 — Surrogate Endpoint (SUR): Blood pressure
Study 17566094 — Surrogate Endpoint (SUR): Bone mineral density
Study 12192247 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 24322997 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17953808 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 15359637 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 8123489 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 2678805 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1170119 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 28331291 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 24411753 — Surrogate Endpoint (SUR): Blood pressure
Study 18983947 — Surrogate Endpoint (SUR): Bone mineral density
Study 26104968 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 24714773 — Predictive Biomarker (PRD): MYL12A mRNA
Genes: MYL12A; MLCB; MRLC3; RLC
Study 10894871 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8507018 — Surrogate Endpoint (SUR): Blood pressure
Study 3877474 — Surrogate Endpoint (SUR): Blood pressure
Study 30301555 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30301555 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20136785 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20136785 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study 1814866 — Surrogate Endpoint (SUR): Blood pressure
Study 17605698 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15479314 — Surrogate Endpoint (SUR): Forced vital capacity
Study 26369798 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26369798 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 26369798 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 21328373 — Monitoring Biomarker (MOI): HBV DNA
Study 2184654 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2184654 — Surrogate Endpoint (SUR): Blood pressure
Study 26099241 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 18451385 — Surrogate Endpoint (SUR): Bone mineral density
Study 16921035 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 7919126 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 31790546 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 30287915 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30287915 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30287915 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 30287915 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 18440674 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 18362295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1425271 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 24759827 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22531338 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22531338 — Surrogate Endpoint (SUR): Blood pressure
Study 16136270 — Surrogate Endpoint (SUR): Blood pressure
Study 7790471 — Predictive Biomarker (PRD): NSMAF mRNA
Genes: NSMAF; FAN
Study 30122341 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28248974 — Surrogate Endpoint (SUR): Blood pressure
Study 24111288 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24111288 — Predictive Biomarker (PRD): ST8SIA4 mRNA
Genes: ST8SIA4; PST; PST1; SIAT8D
Study 24111288 — Surrogate Endpoint (SUR): Blood pressure
Study 21327725 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21327725 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7969676 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 24710641 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 24710641 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 14634760 — Surrogate Endpoint (SUR): Blood pressure
Study 29464879 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29464879 — Surrogate Endpoint (SUR): Serum creatinine
Study 29464879 — Surrogate Endpoint (SUR): Blood pressure
Study 22865548 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1851649 — Predictive Biomarker (PRD): FUT1 mRNA
Genes: FUT1; H; HSC
Study 31769619 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 9694068 — Safety Biomarker (SAF): Hyaluronic acid
Study 25307511 — Surrogate Endpoint (SUR): Blood pressure
Study 20826742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20826742 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27856067 — Surrogate Endpoint (SUR): Bone mineral density
Study 26141466 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14510743 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study 442223 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 22652468 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 12637609 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 12637609 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 18948412 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18075468 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 18075468 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 16441729 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 6354933 — Surrogate Endpoint (SUR): Blood pressure
Study 30779295 — Predictive Biomarker (PRD): FGR mRNA
Genes: FGR; SRC2
Study 21376385 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 14678901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14678901 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 10148188 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16392280 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12356784 — Surrogate Endpoint (SUR): Blood pressure
Study 7787408 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 2338694 — Surrogate Endpoint (SUR): Blood pressure
Study 31793171 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 23324408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11710407 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 11710407 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29629731 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 29629731 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 23975179 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30014565 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 28285617 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24051384 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 31375148 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 20630944 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8942407 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24075527 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 21537491 — Surrogate Endpoint (SUR): Serum calcium
Study 31652404 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 22844043 — Surrogate Endpoint (SUR): Bone mineral density
Study 6783519 — Surrogate Endpoint (SUR): Blood pressure
Study 9819796 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30506451 — Predictive Biomarker (PRD): G0S2 mRNA
Genes: G0S2
Study 30506451 — Predictive Biomarker (PRD): ABHD5 mRNA
Genes: ABHD5; NCIE2; CGI-58
Study 30506451 — Predictive Biomarker (PRD): PNPLA2 mRNA
Genes: PNPLA2; ATGL; FP17548
Study 26023905 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 26023905 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 8986487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31425951 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 27619558 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11800062 — Surrogate Endpoint (SUR): Blood pressure
Study 3340420 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 29650774 — Predictive Biomarker (PRD): CPA6 mRNA
Genes: CPA6; CPAH
Study 29650774 — Predictive Biomarker (PRD): PRPF31 mRNA
Genes: PRPF31; PRP31
Study 29650774 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 27247177 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 11437473 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 7527100 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 4821036 — Predictive Biomarker (PRD): Liver iron
Study 23764639 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21940595 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11160635 — Surrogate Endpoint (SUR): Blood pressure
Study 3056073 — Surrogate Endpoint (SUR): Blood pressure
Study 15660797 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16450017 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 24107844 — Predictive Biomarker (PRD): LILRB4 mRNA
Genes: LILRB4; ILT3; LIR5
Study 24107844 — Predictive Biomarker (PRD): LILRB2 mRNA
Genes: LILRB2; ILT4; LIR2; MIR10
Study 24107844 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24107844 — Pharmacodynamic Biomarker (PDY): C-type lectin domain family 4 member C
Genes: CLEC4C; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; UNQ9361/PRO34150
Study 24107844 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 24107844 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study 17336967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17336967 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9853201 — Surrogate Endpoint (SUR): Blood pressure
Study 21236483 — Surrogate Endpoint (SUR): Blood pressure
Study 7554199 — Surrogate Endpoint (SUR): Blood pressure
Study 28410510 — Surrogate Endpoint (SUR): Blood pressure
Study 16995587 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9292541 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 8038025 — Surrogate Endpoint (SUR): Blood pressure
Study 12975635 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 8967706 — Surrogate Endpoint (SUR): Bone mineral density
Study 2983909 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31843269 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 16505196 — Surrogate Endpoint (SUR): Blood pressure
Study 25905441 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 6083688 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 30541098 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10655977 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 3884577 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 30153453 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30153453 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 15949725 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11101476 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8833212 — Surrogate Endpoint (SUR): Bone mineral density
Study 2859931 — Surrogate Endpoint (SUR): Blood pressure
Study 27340881 — Surrogate Endpoint (SUR): Bone mineral density
Study 22301439 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17651961 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 7768234 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 7768234 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7768234 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2324998 — Surrogate Endpoint (SUR): Blood pressure
Study 218717 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24415784 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 24415784 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24415784 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23094055 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19488605 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 12431240 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 25352508 — Surrogate Endpoint (SUR): Blood pressure
Study 25260393 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16490836 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 11527248 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 18243612 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31829510 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 19066301 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31274211 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31274211 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 31274211 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 28446628 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28446628 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 26070652 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 26070652 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 25002722 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11448848 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 11448848 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 11448848 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 11448848 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9608577 — Surrogate Endpoint (SUR): Blood pressure
Study 22036100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22036100 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11176742 — Surrogate Endpoint (SUR): Serum creatinine
Study 9598258 — Surrogate Endpoint (SUR): Blood pressure
Study 23392717 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23392717 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23392717 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 23392717 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 19549749 — Surrogate Endpoint (SUR): Blood pressure
Study 19549749 — Safety Biomarker (SAF): Urinary microalbumin
Study 9463836 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8302414 — Surrogate Endpoint (SUR): Serum creatinine
Study 18541546 — Surrogate Endpoint (SUR): Blood pressure
Study 6439036 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6439036 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26829088 — Surrogate Endpoint (SUR): Bone mineral density
Study 12559940 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1832982 — Surrogate Endpoint (SUR): Serum creatinine
Study 31182135 — Surrogate Endpoint (SUR): Blood pressure
Study 29255272 — Surrogate Endpoint (SUR): Blood pressure
Study 21153657 — Surrogate Endpoint (SUR): Blood pressure
Study 21153657 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15328781 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22568858 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 16328375 — Predictive Biomarker (PRD): GCSAM mRNA
Genes: GCSAM; GAL; GCET2
Study 11515628 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20472815 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15705978 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 15705978 — Predictive Biomarker (PRD): SPDEF mRNA
Genes: SPDEF; PDEF; PSE
Study 15705978 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 12915698 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8713688 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8713688 — Surrogate Endpoint (SUR): Blood pressure
Study 1714021 — Surrogate Endpoint (SUR): Blood pressure
Study 9037321 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9037321 — Surrogate Endpoint (SUR): Serum calcium
Study 9037321 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31612329 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 24994482 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24994482 — Safety Biomarker (SAF): BDNF
Study 21111986 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21111986 — Surrogate Endpoint (SUR): Blood pressure
Study 18688284 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18688284 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 15972028 — Predictive Biomarker (PRD): STC1 mRNA
Genes: STC1; STC
Study 19016342 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 11597936 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11597936 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9585292 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 9585292 — Surrogate Endpoint (SUR): Forced vital capacity
Study 9129038 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 7948961 — Surrogate Endpoint (SUR): Serum creatinine
Study 20338496 — Surrogate Endpoint (SUR): Blood pressure
Study 20338496 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9579834 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9579834 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 28958504 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 28958504 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 23030252 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP