TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17324220 — Surrogate Endpoint (SUR): Blood pressure
Study 29144805 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 29144805 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 8518408 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30563479 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30563479 — Surrogate Endpoint (SUR): Serum creatinine
Study 10589807 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7060821 — Surrogate Endpoint (SUR): Blood pressure
Study 25084280 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25084280 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17887946 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17887946 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21427643 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 17045826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 17045826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15266207 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 18929499 — Predictive Biomarker (PRD): IGFBP3 mRNA
Genes: IGFBP3; IBP3
Study 20210697 — Predictive Biomarker (PRD): USH1G mRNA
Genes: USH1G; SANS
Study 17620783 — Surrogate Endpoint (SUR): Serum sodium
Study 7042370 — Surrogate Endpoint (SUR): Blood pressure
Study 24177001 — Predictive Biomarker (PRD): LOXL2 mRNA
Genes: LOXL2
Study 9655769 — Predictive Biomarker (PRD): ANG mRNA
Genes: ANG; RNASE5
Study 9655769 — Surrogate Endpoint (SUR): Blood pressure
Study 7658819 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2787297 — Surrogate Endpoint (SUR): Blood pressure
Study 2787297 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21701268 — Predictive Biomarker (PRD): SPAG9 mRNA
Genes: SPAG9; HSS; KIAA0516; MAPK8IP4; SYD1; HLC6
Study 21701268 — Surrogate Endpoint (SUR): Serum creatinine
Study 19798725 — Predictive Biomarker (PRD): SGCA mRNA
Genes: SGCA; ADL; DAG2
Study 19798725 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19798725 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 17102650 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 15526307 — Surrogate Endpoint (SUR): Blood pressure
Study 7560695 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 7560695 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 28946736 — Monitoring Biomarker (MOI): HBV DNA
Study 24135303 — Surrogate Endpoint (SUR): Blood pressure
Study 17944632 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28433267 — Surrogate Endpoint (SUR): Serum calcium
Study 25618125 — Predictive Biomarker (PRD): CLNK mRNA
Genes: CLNK; MIST
Study 21262931 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22791944 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 22791944 — Safety Biomarker (SAF): Th2 cell
Study 22791944 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 17214829 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9748876 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 7923515 — Surrogate Endpoint (SUR): Blood pressure
Study 31302586 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27595680 — Surrogate Endpoint (SUR): Serum creatinine
Study 18608712 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 12381942 — Surrogate Endpoint (SUR): Bone mineral density
Study 12381942 — Surrogate Endpoint (SUR): Serum calcium
Study 29100778 — Predictive Biomarker (PRD): SAA1 mRNA
Genes: SAA1
Study 29100778 — Monitoring Biomarker (MOI): Procalcitonin
Study 29100778 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21362275 — Surrogate Endpoint (SUR): Blood pressure
Study 19920269 — Surrogate Endpoint (SUR): Blood pressure
Study 2560684 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 28608926 — Surrogate Endpoint (SUR): Blood pressure
Study 21649532 — Surrogate Endpoint (SUR): Blood pressure
Study 14715848 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 14715848 — Surrogate Endpoint (SUR): Bone mineral density
Study 9134917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9134917 — Safety Biomarker (SAF): Interleukin 1
Study 7950180 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 26277548 — Surrogate Endpoint (SUR): Serum calcium
Study 18400718 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 12725879 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 1568584 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3158321 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 3158321 — Predictive Biomarker (PRD): LPL mRNA
Genes: LPL; LIPD
Study 3158321 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 3158321 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31822925 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30352583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24952865 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 8679357 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 8679357 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 6344698 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18702848 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23563245 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 20431530 — Surrogate Endpoint (SUR): Serum uric acid
Study 12192104 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 12192104 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 7754939 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26303134 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 26303134 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 17671215 — Predictive Biomarker (PRD): TNFSF10 mRNA
Genes: TNFSF10; APO2L; TRAIL
Study 17671215 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 17671215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11973440 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11973440 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28545564 — Surrogate Endpoint (SUR): Blood pressure
Study 17449575 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 12154422 — Surrogate Endpoint (SUR): Blood pressure
Study 10604523 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10604523 — Surrogate Endpoint (SUR): Blood pressure
Study 30063723 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30063723 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 30063723 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 30063723 — Predictive Biomarker (PRD): FLT4 mRNA
Genes: FLT4; VEGFR3
Study 30063723 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30063723 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24938324 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20368057 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 19337557 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12781159 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 6871083 — Surrogate Endpoint (SUR): Blood pressure
Study 30115121 — Predictive Biomarker (PRD): GRIK1 mRNA
Genes: GRIK1; GLUR5
Study 27181886 — Surrogate Endpoint (SUR): Blood pressure
Study 22264278 — Predictive Biomarker (PRD): SLC13A5 mRNA
Genes: SLC13A5; NACT
Study 22264278 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 22264278 — Predictive Biomarker (PRD): PTGDS mRNA
Genes: PTGDS; PDS
Study 19174703 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19174703 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23169292 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23169292 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23169292 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 10830415 — Predictive Biomarker (PRD): PAICS mRNA
Genes: PAICS; ADE2; AIRC; PAIS
Study 9014744 — Surrogate Endpoint (SUR): Serum calcium
Study 28007665 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 28007665 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 26139733 — Surrogate Endpoint (SUR): Blood pressure
Study 15203886 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9479357 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 7931484 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18716528 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30425104 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 24168291 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18050629 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 18312872 — Predictive Biomarker (PRD): DEFA1 mRNA
Genes: DEFA1; DEF1; DEFA2; MRS; DEFA1B
Study 1697914 — Surrogate Endpoint (SUR): Blood pressure
Study 28416836 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28416836 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 28416836 — Predictive Biomarker (PRD): FBXO8 mRNA
Genes: FBXO8; FBS; FBX8; DC10; UNQ1877/PRO4320
Study 28416836 — Surrogate Endpoint (SUR): Blood pressure
Study 21316442 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 21316442 — Surrogate Endpoint (SUR): Bone mineral density
Study 17536871 — Surrogate Endpoint (SUR): Forced vital capacity
Study 14973517 — Surrogate Endpoint (SUR): Blood pressure
Study 14973517 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2596737 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 29090352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29090352 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16902063 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16902063 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1895677 — Surrogate Endpoint (SUR): Urinary oxalate
Study 28247026 — Surrogate Endpoint (SUR): Blood pressure
Study 23972263 — Surrogate Endpoint (SUR): Total kidney volume
Study 16730924 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 30562772 — Predictive Biomarker (PRD): SSB mRNA
Genes: SSB
Study 30562772 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 22910317 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22910317 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 22910317 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16138418 — Surrogate Endpoint (SUR): Blood pressure
Study 16138418 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 11873071 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11873071 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 27841974 — Predictive Biomarker (PRD): Tetranectin
Genes: CLEC3B; TNA
Study 25072098 — Predictive Biomarker (PRD): CHRNA5 mRNA
Genes: CHRNA5; NACHRA5
Study 25072098 — Predictive Biomarker (PRD): CHRNA3 mRNA
Genes: CHRNA3; NACHRA3
Study 25072098 — Predictive Biomarker (PRD): CHRNB4 mRNA
Genes: CHRNB4
Study 25072098 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 23152839 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 15730171 — Surrogate Endpoint (SUR): Bone mineral density
Study 11889394 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 24909481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12037739 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 10562483 — Surrogate Endpoint (SUR): Blood pressure
Study 31343603 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23797054 — Surrogate Endpoint (SUR): Blood pressure
Study 19699855 — Surrogate Endpoint (SUR): Blood pressure
Study 19699855 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8998091 — Surrogate Endpoint (SUR): Blood pressure
Study 3553493 — Surrogate Endpoint (SUR): Blood pressure
Study 24464974 — Predictive Biomarker (PRD): TNS4 mRNA
Genes: TNS4; CTEN; PP14434
Study 24464974 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15754390 — Monitoring Biomarker (MOI): HBV DNA
Study 6192894 — Predictive Biomarker (PRD): COPB1 mRNA
Genes: COPB1; COPB; MSTP026
Study 31958178 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 31958178 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 24722261 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 23673286 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 23673286 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 23673286 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 23673286 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30758896 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 11382895 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 4006345 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 4006345 — Surrogate Endpoint (SUR): Blood pressure
Study 27612562 — Predictive Biomarker (PRD): COPE mRNA
Genes: COPE
Study 23316080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21211331 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21211331 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 31474546 — Predictive Biomarker (PRD): MPL mRNA
Genes: MPL; TPOR
Study 24334318 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24334318 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20104986 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15986591 — Surrogate Endpoint (SUR): Pathological complete response
Study 26134993 — Predictive Biomarker (PRD): FHL5 mRNA
Genes: FHL5; ACT
Study 1670113 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 21862748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10981543 — Surrogate Endpoint (SUR): Blood pressure
Study 9191677 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29330256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29330256 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21810842 — Surrogate Endpoint (SUR): Blood pressure
Study 19952833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19952833 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19952833 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 18082451 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 1465060 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30223226 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30223226 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30223226 — Predictive Biomarker (PRD): Hormone receptor
Study 27565964 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11595781 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 22129488 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17879533 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 2576663 — Surrogate Endpoint (SUR): Blood pressure
Study 23116451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23116451 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23116451 — Safety Biomarker (SAF): IL-6 and IL-10
Study 18641546 — Predictive Biomarker (PRD): UGT2B7 mRNA
Genes: UGT2B7; UGTB2B9
Study 1850946 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22703478 — Surrogate Endpoint (SUR): Blood pressure
Study 11930721 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 25498787 — Surrogate Endpoint (SUR): Blood pressure
Study 21112921 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18688808 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study 18688808 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 17044955 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10546926 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10546926 — Safety Biomarker (SAF): Interleukin 12
Study 10546926 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 28516874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28516874 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25156114 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22505700 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 10462143 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 31751687 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 31751687 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 31751687 — Pharmacodynamic Biomarker (PDY): Mitochondrial membrane potential
Study 15325927 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 9786311 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 25171902 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 6268131 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6268131 — Surrogate Endpoint (SUR): Blood pressure
Study 27117700 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 17990450 — Predictive Biomarker (PRD): FYN mRNA
Genes: FYN
Study 7919085 — Surrogate Endpoint (SUR): Blood pressure
Study 24363761 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 20557887 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 20557887 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 17367358 — Surrogate Endpoint (SUR): Serum creatinine
Study 19215577 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 19215577 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14623703 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14623703 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10922312 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10922312 — Safety Biomarker (SAF): Interleukin 1
Study 10922312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10922312 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20812958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20812958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20812958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20812958 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16369725 — Surrogate Endpoint (SUR): Bone mineral density
Study 10948088 — Surrogate Endpoint (SUR): Blood pressure
Study 28953669 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28953669 — Surrogate Endpoint (SUR): Blood pressure
Study 18297248 — Surrogate Endpoint (SUR): Blood pressure
Study 11993408 — Surrogate Endpoint (SUR): Blood pressure
Study 11993408 — Surrogate Endpoint (SUR): Serum creatinine
Study 8188888 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 17934668 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 9869176 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 27077121 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 22012970 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19254816 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 17197807 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1875405 — Surrogate Endpoint (SUR): Blood pressure
Study 31446213 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL