TrialPanorama/TrialPanorama-database huggingface dataset:
Study 15654172 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12208593 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25041227 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAV1 mRNA
Genes: CAV1; CAV
Study 22299599 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15662209 — Surrogate Endpoint (SUR): Blood pressure
Study 7096960 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 25712437 — Surrogate Endpoint (SUR): Serum creatinine
Study 12502654 — Surrogate Endpoint (SUR): Blood pressure
Study 7081117 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28982740 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28982740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18696359 — Surrogate Endpoint (SUR): Blood pressure
Study 10220271 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10220271 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 26046796 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 26046796 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 24093487 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24093487 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 11157314 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 31617739 — Surrogate Endpoint (SUR): Blood pressure
Study 24102851 — Surrogate Endpoint (SUR): Blood pressure
Study 19925286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 10356097 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 8832603 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 29171086 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30764560 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 19769793 — Predictive Biomarker (PRD): UCP2 mRNA
Genes: UCP2; SLC25A8
Study 19769793 — Predictive Biomarker (PRD): UCP3 mRNA
Genes: UCP3; SLC25A9
Study 14972792 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 14972792 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 30711649 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 29142982 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 29142982 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 29142982 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9358138 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28190787 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 28190787 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19538718 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 16951642 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20627015 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27565734 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1713269 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1713269 — Safety Biomarker (SAF): Coagulation factor Va
Genes: F5
Study 1713269 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 1713269 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17272969 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 402569 — Surrogate Endpoint (SUR): Blood pressure
Study 31265450 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11304662 — Surrogate Endpoint (SUR): Blood pressure
Study 7948814 — Predictive Biomarker (PRD): PGC mRNA
Genes: PGC
Study 3063488 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23596158 — Surrogate Endpoint (SUR): Blood pressure
Study 23596158 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 18199149 — Surrogate Endpoint (SUR): Probing pocket depth
Study 16775595 — Surrogate Endpoint (SUR): Blood pressure
Study 16775595 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1449044 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 29413685 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 29413685 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29413685 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29413685 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 17487649 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17487649 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7033014 — Surrogate Endpoint (SUR): Blood pressure
Study 31289019 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 30447975 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31399442 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 19214552 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 8020690 — Surrogate Endpoint (SUR): Blood pressure
Study 19167684 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 8254181 — Surrogate Endpoint (SUR): Blood pressure
Study 30063180 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 30063180 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 23849811 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 6385893 — Surrogate Endpoint (SUR): Blood pressure
Study 30756302 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 29654805 — Predictive Biomarker (PRD): INTU mRNA
Genes: INTU; KIAA1284; PDZD6; PDZK6
Study 29654805 — Surrogate Endpoint (SUR): Serum sodium
Study 8704351 — Surrogate Endpoint (SUR): Bone mineral density
Study 30698675 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 27930553 — Safety Biomarker (SAF): Hyaluronic acid
Study 24785399 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 19361146 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22833684 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22833684 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 26840438 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 8558194 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 28833192 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28833192 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28833192 — Safety Biomarker (SAF): BDNF
Study 18926645 — Surrogate Endpoint (SUR): Blood pressure
Study 17698275 — Predictive Biomarker (PRD): SPIN1 mRNA
Genes: SPIN1; OCR; SPIN
Study 17698275 — Predictive Biomarker (PRD): NNT mRNA
Genes: NNT
Study 23376362 — Monitoring Biomarker (MOI): HBV DNA
Study 12815565 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31902378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31902378 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30998063 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 26000667 — Predictive Biomarker (PRD): SERPINA2 mRNA
Genes: SERPINA2; ARGS; ATR; PIL; SERPINA2P
Study 8001628 — Surrogate Endpoint (SUR): Serum triglycerides
Study 14621746 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 26118825 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23865389 — Surrogate Endpoint (SUR): Serum creatinine
Study 21717822 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21717822 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21717822 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21717822 — Surrogate Endpoint (SUR): Serum creatinine
Study 20479668 — Surrogate Endpoint (SUR): Blood pressure
Study 9756248 — Surrogate Endpoint (SUR): Blood pressure
Study 7804510 — Surrogate Endpoint (SUR): Blood pressure
Study 22639013 — Surrogate Endpoint (SUR): Blood pressure
Study 19224430 — Predictive Biomarker (PRD): RBP4 mRNA
Genes: RBP4; PRO2222
Study 11602545 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11602545 — Surrogate Endpoint (SUR): Blood pressure
Study 7614520 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7614520 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2146369 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 28332191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24142853 — Surrogate Endpoint (SUR): Blood pressure
Study 1764956 — Surrogate Endpoint (SUR): Blood pressure
Study 30943275 — Surrogate Endpoint (SUR): Blood pressure
Study 22438298 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25074318 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25074318 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 25074318 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8098220 — Surrogate Endpoint (SUR): Serum potassium
Study 8098220 — Surrogate Endpoint (SUR): Blood pressure
Study 31568587 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31568587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31568587 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 31568587 — Safety Biomarker (SAF): Interleukin 12
Study 28551073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26228487 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 18652688 — Predictive Biomarker (PRD): GK mRNA
Genes: GK
Study 11921591 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11921591 — Surrogate Endpoint (SUR): Blood pressure
Study 31651545 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 410176 — Surrogate Endpoint (SUR): Blood pressure
Study 30776911 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23480523 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21665007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21665007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21665007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11336159 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 3655855 — Predictive Biomarker (PRD): MERTK mRNA
Genes: MERTK; MER
Study 3655855 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 31987106 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 27102821 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 24441153 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24441153 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18474338 — Surrogate Endpoint (SUR): Blood pressure
Study 18474338 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 350500 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11195315 — Surrogate Endpoint (SUR): Bone mineral density
Study 20103724 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 16140708 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16140708 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16140708 — Surrogate Endpoint (SUR): Blood pressure
Study 30990099 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 8933551 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 30712751 — Surrogate Endpoint (SUR): Blood pressure
Study 28225475 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 28225475 — Predictive Biomarker (PRD): ROS1
Genes: MCF3; ROS; c-ros-1
Study 28225475 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28225475 — Safety Biomarker (SAF): Reactive oxygen species
Study 28225475 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19476473 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11641371 — Surrogate Endpoint (SUR): Plasma ammonia
Study 9734766 — Surrogate Endpoint (SUR): Blood pressure
Study 24006749 — Surrogate Endpoint (SUR): Blood pressure
Study 21106985 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 18356327 — Surrogate Endpoint (SUR): Blood pressure
Study 16214598 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 10408591 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10408591 — Surrogate Endpoint (SUR): Blood pressure
Study 30586698 — Surrogate Endpoint (SUR): Blood pressure
Study 21294929 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 21294929 — Surrogate Endpoint (SUR): Blood pressure
Study 19696440 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17355733 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 3072180 — Surrogate Endpoint (SUR): Blood pressure
Study 30803434 — Surrogate Endpoint (SUR): Total kidney volume
Study 20189611 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20189611 — Surrogate Endpoint (SUR): Serum creatinine
Study 12818245 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18001269 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 27575011 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 27575011 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9683397 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 29128507 — Predictive Biomarker (PRD): KL mRNA
Genes: KL
Study 24560157 — Surrogate Endpoint (SUR): Urinary oxalate
Study 20664891 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11869839 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 22707271 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 22707271 — Surrogate Endpoint (SUR): Blood pressure
Study 12783370 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 12783370 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 12783370 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 10893682 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 19765066 — Surrogate Endpoint (SUR): Blood pressure
Study 3056431 — Surrogate Endpoint (SUR): Serum triglycerides
Study 31780418 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 25986590 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 17823446 — Surrogate Endpoint (SUR): Bone mineral density
Study 15114779 — Predictive Biomarker (PRD): LPO mRNA
Genes: LPO; SAPX
Study 31722135 — Safety Biomarker (SAF): Reactive oxygen species
Study 23908125 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19552744 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 11456368 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 27443525 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17083726 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 15617307 — Surrogate Endpoint (SUR): Blood pressure
Study 24567316 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23731980 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20629545 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 12959938 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10664525 — Surrogate Endpoint (SUR): Serum testosterone
Study 30408722 — Predictive Biomarker (PRD): NR3C1 mRNA
Genes: NR3C1; GRL
Study 14556808 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 3768764 — Surrogate Endpoint (SUR): Blood pressure
Study 18677171 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12612947 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 12612947 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12612947 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12612947 — Surrogate Endpoint (SUR): Blood pressure
Study 10491228 — Surrogate Endpoint (SUR): Bone mineral density
Study 26864124 — Surrogate Endpoint (SUR): Blood pressure
Study 26864124 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21849640 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 24019415 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 19487264 — Surrogate Endpoint (SUR): Bone mineral density
Study 12617709 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 9105988 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 3770017 — Surrogate Endpoint (SUR): Blood pressure
Study 29531173 — Surrogate Endpoint (SUR): Blood pressure
Study 23733907 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22640372 — Surrogate Endpoint (SUR): Bone mineral density
Study 21357180 — Surrogate Endpoint (SUR): Blood pressure
Study 19641488 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19641488 — Predictive Biomarker (PRD): NTRK2 mRNA
Genes: NTRK2; TRKB
Study 19641488 — Predictive Biomarker (PRD): ADRA2A mRNA
Genes: ADRA2A; ADRA2R; ADRAR
Study 19641488 — Safety Biomarker (SAF): BDNF
Study 28774794 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 26477692 — Predictive Biomarker (PRD): IL1RN mRNA
Genes: IL1RN; IL1F3; IL1RA
Study 26477692 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26477692 — Safety Biomarker (SAF): Interleukin 1
Study 19705205 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17189962 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 17189962 — Safety Biomarker (SAF): DRD2
Study 15371578 — Monitoring Biomarker (MOI): HBV DNA
Study 9842823 — Surrogate Endpoint (SUR): Blood pressure
Study 8080740 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 31675420 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 31675420 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 31675420 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31675420 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31675420 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 27755057 — Surrogate Endpoint (SUR): Blood pressure
Study 23800977 — Surrogate Endpoint (SUR): Blood pressure
Study 18353314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18353314 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 27956407 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2898027 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2898027 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 21298859 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7957544 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 31909431 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15131558 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9310811 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9310811 — Surrogate Endpoint (SUR): Blood pressure
Study 23701262 — Predictive Biomarker (PRD): HCAR2 mRNA
Genes: HCAR2; GPR109A; HCA2; HM74A; NIACR1
Study 23701262 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 19926370 — Surrogate Endpoint (SUR): Serum creatinine
Study 25945079 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 25945079 — Surrogate Endpoint (SUR): Blood pressure
Study 11434941 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9887454 — Surrogate Endpoint (SUR): Blood pressure
Study 18405061 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 10997957 — Surrogate Endpoint (SUR): Serum testosterone
Study 8792252 — Surrogate Endpoint (SUR): Bone mineral density
Study 30862817 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22434095 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17660173 — Surrogate Endpoint (SUR): Blood pressure
Study 23751727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19934290 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 19934290 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19934290 — Predictive Biomarker (PRD): Microsatellite instability
Study 14724047 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31648986 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 21318637 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 15556053 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9105945 — Surrogate Endpoint (SUR): Blood pressure