TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24016864 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15191344 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15191344 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15191344 — Predictive Biomarker (PRD): PPA1 mRNA
Genes: PPA1; IOPPP; PP
Study 15191344 — Surrogate Endpoint (SUR): Blood pressure
Study 9233740 — Surrogate Endpoint (SUR): Blood pressure
Study 9233740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8423228 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28067719 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 28067719 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 30348101 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 30348101 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20881283 — Surrogate Endpoint (SUR): Blood pressure
Study 19031508 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 19031508 — Surrogate Endpoint (SUR): Bone mineral density
Study 10425010 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 19417610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19417610 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19417610 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 19417610 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19417610 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 29380956 — Predictive Biomarker (PRD): FADD mRNA
Genes: FADD; MORT1; GIG3
Study 29380956 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 29380956 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study 29380956 — Predictive Biomarker (PRD): CASP9
Genes: MCH6; ICE-LAP6; APAF-3; PPP1R56
Study 23292674 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 10502079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10502079 — Safety Biomarker (SAF): IL-6 and IL-10
Study 12915593 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24938562 — Predictive Biomarker (PRD): GNAQ mRNA
Genes: GNAQ; GAQ
Study 24938562 — Predictive Biomarker (PRD): MAP2K1 mRNA
Genes: MAP2K1; MEK1; PRKMK1
Study 24938562 — Predictive Biomarker (PRD): MAP2K2 mRNA
Genes: MAP2K2; MEK2; MKK2; PRKMK2
Study 23136545 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 10483952 — Surrogate Endpoint (SUR): Blood pressure
Study 8963892 — Predictive Biomarker (PRD): SHD mRNA
Genes: SHD
Study 8963892 — Surrogate Endpoint (SUR): Blood pressure
Study 12544868 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16734607 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24755339 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18004285 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 2189551 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 25912560 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19129278 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19129278 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17285888 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 14583440 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 10682134 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 2492741 — Surrogate Endpoint (SUR): Blood pressure
Study 30455077 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 11923809 — Surrogate Endpoint (SUR): Blood pressure
Study 9934939 — Surrogate Endpoint (SUR): Serum testosterone
Study 2110575 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 19939874 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 7948449 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 7948449 — Predictive Biomarker (PRD): PTK7 mRNA
Genes: PTK7; CCK4
Study 7948449 — Surrogate Endpoint (SUR): Blood pressure
Study 24076594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24076594 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24076594 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 16009883 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 8603942 — Monitoring Biomarker (MOI): Complement C7
Genes: C7
Study 22065199 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 24687927 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 7000243 — Surrogate Endpoint (SUR): Blood pressure
Study 23672349 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 23672349 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 29752869 — Predictive Biomarker (PRD): ABO mRNA
Genes: ABO
Study 22913889 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22913889 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7846197 — Surrogate Endpoint (SUR): Blood pressure
Study 3132360 — Surrogate Endpoint (SUR): Blood pressure
Study 23289728 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 12952249 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12952249 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 12952249 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 1576067 — Surrogate Endpoint (SUR): Serum sodium
Study 1576067 — Surrogate Endpoint (SUR): Blood pressure
Study 11439738 — Surrogate Endpoint (SUR): Blood pressure
Study 8458096 — Surrogate Endpoint (SUR): Blood pressure
Study 10754428 — Surrogate Endpoint (SUR): Blood pressure
Study 27756097 — Predictive Biomarker (PRD): ME1 mRNA
Genes: ME1
Study 26764966 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22847212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22847212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22847212 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28115830 — Predictive Biomarker (PRD); Safety Biomarker (SAF): COX2 mRNA
Genes: PTGS2; COX2
Study 25697431 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19406886 — Surrogate Endpoint (SUR): Blood pressure
Study 12686336 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8905804 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 20720259 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 12182251 — Surrogate Endpoint (SUR): Blood pressure
Study 8974212 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23589565 — Surrogate Endpoint (SUR): Blood pressure
Study 9175967 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 4014015 — Surrogate Endpoint (SUR): Blood pressure
Study 30925958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30925958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30925958 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30925958 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17414346 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9871930 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 27030648 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 24886225 — Surrogate Endpoint (SUR): Blood pressure
Study 15724142 — Predictive Biomarker (PRD): DRD4 mRNA
Genes: DRD4
Study 15724142 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 10645192 — Surrogate Endpoint (SUR): Bone mineral density
Study 30765407 — Predictive Biomarker (PRD): LSS mRNA
Genes: LSS; OSC
Study 10840537 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10840537 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31764468 — Surrogate Endpoint (SUR): Blood pressure
Study 12145009 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 12145009 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19675744 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19675744 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17170202 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 11470011 — Surrogate Endpoint (SUR): Blood pressure
Study 4051323 — Surrogate Endpoint (SUR): Forced vital capacity
Study 19295225 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16886936 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 11740417 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 11740417 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11740417 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11740417 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20395857 — Surrogate Endpoint (SUR): Serum calcium
Study 20395857 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 8735778 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 7038076 — Surrogate Endpoint (SUR): Blood pressure
Study 30909877 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30909877 — Surrogate Endpoint (SUR): Blood pressure
Study 24245880 — Safety Biomarker (SAF): Hyaluronic acid
Study 22955227 — Surrogate Endpoint (SUR): Blood pressure
Study 19838098 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19838098 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25647646 — Predictive Biomarker (PRD): SIT1 mRNA
Genes: SIT1; SIT
Study 23339726 — Surrogate Endpoint (SUR): Blood pressure
Study 23339726 — Surrogate Endpoint (SUR): Serum creatinine
Study 23339726 — Surrogate Endpoint (SUR): Serum potassium
Study 21401585 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA
Study 22494856 — Safety Biomarker (SAF): Hyaluronic acid
Study 20236216 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 17916949 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15613422 — Surrogate Endpoint (SUR): Bone mineral density
Study 10404946 — Surrogate Endpoint (SUR): Blood pressure
Study 28472315 — Surrogate Endpoint (SUR): Blood pressure
Study 6962709 — Surrogate Endpoint (SUR): Blood pressure
Study 6962709 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12047481 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 1703602 — Surrogate Endpoint (SUR): Blood pressure
Study 26261902 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 20437580 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20437580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20437580 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 20437580 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 31045465 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25853236 — Surrogate Endpoint (SUR): Blood pressure
Study 21290145 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 21290145 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 8607394 — Surrogate Endpoint (SUR): Blood pressure
Study 2006246 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 26324089 — Predictive Biomarker (PRD): HNF1A mRNA
Genes: HNF1A; TCF1
Study 23151017 — Surrogate Endpoint (SUR): Blood pressure
Study 21873490 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 18294116 — Surrogate Endpoint (SUR): Blood pressure
Study 18294116 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15293527 — Surrogate Endpoint (SUR): Blood pressure
Study 3319637 — Surrogate Endpoint (SUR): Blood pressure
Study 27245928 — Surrogate Endpoint (SUR): Blood pressure
Study 20360753 — Surrogate Endpoint (SUR): Blood pressure
Study 15998652 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19345451 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 19345451 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 14981006 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 3133924 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 22018299 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 8736266 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30165858 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30165858 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 30165858 — Safety Biomarker (SAF): Lactotransferrin
Genes: LTF; GIG12; LF
Study 30165858 — Surrogate Endpoint (SUR): Blood pressure
Study 10389286 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7035184 — Surrogate Endpoint (SUR): Blood pressure
Study 29045610 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 24678280 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 24678280 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 24678280 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12084522 — Surrogate Endpoint (SUR): Blood pressure
Study 7867870 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 17093179 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 27195814 — Surrogate Endpoint (SUR): Blood pressure
Study 15683479 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 12586452 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 16586308 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 7491881 — Surrogate Endpoint (SUR): Plasma phenylalanine
Study 16998094 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 12151034 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 12151034 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23768612 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22439807 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22439807 — Surrogate Endpoint (SUR): Bone mineral density
Study 22439807 — Surrogate Endpoint (SUR): Serum testosterone
Study 28693531 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21992490 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study 26045340 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28454831 — Surrogate Endpoint (SUR): Blood pressure
Study 15307696 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 15307696 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 15307696 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15307696 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 15307696 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10835440 — Surrogate Endpoint (SUR): Blood pressure
Study 29133080 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29133080 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 25185672 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 22268920 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 22268920 — Safety Biomarker (SAF): Hepatitis A virus cellular receptor 1
Genes: HAVCR1; KIM1; TIM1; TIMD1
Study 15340661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15340661 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22702906 — Predictive Biomarker (PRD): Solute carrier family 29 member 1
Genes: SLC29A1; ENT1
Study 9426331 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8032065 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 24519387 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24519387 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 24519387 — Predictive Biomarker (PRD): Hormone receptor
Study 20449757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18937897 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18937897 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11033842 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 8993754 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8993754 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30782586 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 28602711 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 23724696 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 20546501 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9162610 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 28277426 — Safety Biomarker (SAF): Reactive oxygen species
Study 27215502 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 27215502 — Surrogate Endpoint (SUR): Forced vital capacity
Study 1907075 — Surrogate Endpoint (SUR): Serum testosterone
Study 31060559 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31060559 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25815454 — Surrogate Endpoint (SUR): Blood pressure
Study 17233787 — Predictive Biomarker (PRD): MCAT mRNA
Genes: MCAT; MT
Study 11772706 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 824298 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 824298 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 30848791 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 11204315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27756485 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 22307266 — Predictive Biomarker (PRD): Hormone receptor
Study 22307266 — Surrogate Endpoint (SUR): Bone mineral density
Study 30875354 — Surrogate Endpoint (SUR): Blood pressure
Study 16821119 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 9878017 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7044529 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28391880 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12236852 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12236852 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7567754 — Surrogate Endpoint (SUR): Blood pressure
Study 2246608 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2246608 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26472263 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26472263 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 23672977 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 15374846 — Surrogate Endpoint (SUR): Bone mineral density
Study 8942332 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 4016930 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 31551029 — Predictive Biomarker (PRD): TRERF1 mRNA
Genes: TRERF1; BCAR2; RAPA; TREP132
Study 28679946 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 26061132 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26061132 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22031660 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 1552198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1552198 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26546248 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20602168 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20602168 — Surrogate Endpoint (SUR): Serum creatinine
Study 17243612 — Surrogate Endpoint (SUR): Blood pressure
Study 14671204 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 14671204 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15988284 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 6696838 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23769296 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18972276 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29497289 — Surrogate Endpoint (SUR): Forced vital capacity
Study 20400095 — Surrogate Endpoint (SUR): Blood pressure
Study 18208957 — Surrogate Endpoint (SUR): Blood pressure
Study 16200612 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 12740515 — Predictive Biomarker (PRD): CS mRNA
Genes: CS