TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28079606 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28079606 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study 28079606 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 11812666 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 10409470 — Surrogate Endpoint (SUR): Serum calcium
Study 2147517 — Surrogate Endpoint (SUR): Blood pressure
Study 6614412 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 20308718 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 20308718 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 20308718 — Predictive Biomarker (PRD): NR1D1 mRNA
Genes: NR1D1; EAR1; HREV; THRAL
Study 10096264 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6756509 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 25944411 — Surrogate Endpoint (SUR): Bone mineral density
Study 9039852 — Surrogate Endpoint (SUR): Blood pressure
Study 30030775 — Surrogate Endpoint (SUR): Blood pressure
Study 30030775 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24453079 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24453079 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24767296 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 24767296 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 11978683 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 8095941 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30043330 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30043330 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 24632673 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 12089229 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 29326491 — Surrogate Endpoint (SUR): Blood pressure
Study 16624680 — Surrogate Endpoint (SUR): Blood pressure
Study 10762502 — Predictive Biomarker (PRD): FXYD1 mRNA
Genes: FXYD1; PLM
Study 1359846 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1921255 — Surrogate Endpoint (SUR): Blood pressure
Study 30362649 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 30362649 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11375808 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 9404430 — Surrogate Endpoint (SUR): Blood pressure
Study 30844477 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study 3511660 — Surrogate Endpoint (SUR): Blood pressure
Study 11464141 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11464141 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 16023828 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16023828 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12830447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31268250 — Predictive Biomarker (PRD): HCAR2 mRNA
Genes: HCAR2; GPR109A; HCA2; HM74A; NIACR1
Study 31268250 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30572911 — Predictive Biomarker (PRD): EIF2AK3 mRNA
Genes: EIF2AK3; PEK; PERK
Study 30572911 — Predictive Biomarker (PRD): EPRS1 mRNA
Genes: EPRS1; EPRS; GLNS; PARS; QARS; QPRS; PIG32
Study 30572911 — Predictive Biomarker (PRD): GALE mRNA
Genes: GALE
Study 30572911 — Predictive Biomarker (PRD): GUCY2C mRNA
Genes: GUCY2C; GUC2C; STAR
Study 30572911 — Predictive Biomarker (PRD): MTHFD2 mRNA
Genes: MTHFD2; NMDMC
Study 30572911 — Predictive Biomarker (PRD): RNF212 mRNA
Genes: RNF212
Study 27010201 — Surrogate Endpoint (SUR): Blood pressure
Study 23091096 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 3974451 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8592955 — Surrogate Endpoint (SUR): Bone mineral density
Study 21611972 — Surrogate Endpoint (SUR): Bone mineral density
Study 9036608 — Predictive Biomarker (PRD): EHF mRNA
Genes: EHF; ESE3; ESE3B; ESEJ
Study 1480446 — Surrogate Endpoint (SUR): Forced vital capacity
Study 29534661 — Surrogate Endpoint (SUR): Serum creatinine
Study 26814104 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 26814104 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 26814104 — Surrogate Endpoint (SUR): Blood pressure
Study 16536764 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 8428859 — Surrogate Endpoint (SUR): Blood pressure
Study 16504397 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 10983647 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15950945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9659136 — Surrogate Endpoint (SUR): Bone mineral density
Study 30077530 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18498915 — Surrogate Endpoint (SUR): Blood pressure
Study 15948086 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12013192 — Safety Biomarker (SAF): Reactive oxygen species
Study 10412820 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 10412820 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 22902324 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 22902324 — Predictive Biomarker (PRD): ERCC2 mRNA
Genes: ERCC2; XPD; XPDC
Study 20875219 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 28444396 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 21146458 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 9112670 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9826308 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study 9826308 — Surrogate Endpoint (SUR): Blood pressure
Study 15041391 — Surrogate Endpoint (SUR): Serum creatinine
Study 23941324 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 14671052 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 14671052 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 14671052 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3906674 — Surrogate Endpoint (SUR): Serum potassium
Study 3906674 — Surrogate Endpoint (SUR): Serum sodium
Study 24597251 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24597251 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24597251 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 10622295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12365085 — Surrogate Endpoint (SUR): Blood pressure
Study 9834008 — Predictive Biomarker (PRD): Coagulation factor VIII
Genes: F8; F8C
Study 30704182 — Surrogate Endpoint (SUR): Blood pressure
Study 12759298 — Surrogate Endpoint (SUR): Serum uric acid
Study 27128831 — Predictive Biomarker (PRD): SERPINA6 mRNA
Genes: SERPINA6; CBG
Study 27128831 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 22427895 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 20848369 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 15655129 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 15655129 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31175806 — Predictive Biomarker (PRD): NOS2 mRNA
Genes: NOS2; NOS2A
Study 31175806 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 23162100 — Surrogate Endpoint (SUR): Bone mineral density
Study 19390093 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19390093 — Surrogate Endpoint (SUR): Blood pressure
Study 29736750 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 27393622 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27393622 — Predictive Biomarker (PRD): Hormone receptor
Study 16110851 — Predictive Biomarker (PRD): EVL mRNA
Genes: EVL; RNB6
Study 8520875 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8520875 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 23510357 — Surrogate Endpoint (SUR): Serum bactericidal antibody
Study 17130680 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 12584276 — Surrogate Endpoint (SUR): Blood pressure
Study 9116774 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 1439226 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3104446 — Surrogate Endpoint (SUR): Blood pressure
Study 31843821 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30024030 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27461133 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10682871 — Surrogate Endpoint (SUR): Serum uric acid
Study 9054254 — Surrogate Endpoint (SUR): Blood pressure
Study 30043208 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 30043208 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 27052561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27052561 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 24748630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11391837 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23905377 — Predictive Biomarker (PRD): SP6 mRNA
Genes: SP6; KLF14
Study 11514377 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11514377 — Surrogate Endpoint (SUR): Blood pressure
Study 19501932 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19501932 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 19501932 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16492843 — Predictive Biomarker (PRD): CPOX mRNA
Genes: CPOX; CPO; CPX
Study 11865966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9832292 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 2475682 — Surrogate Endpoint (SUR): Blood pressure
Study 30753203 — Surrogate Endpoint (SUR): Blood pressure
Study 19725594 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 21247745 — Predictive Biomarker (PRD): ROPN1L mRNA
Genes: ROPN1L; ASP; RSPH11
Study 21247745 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 15988705 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29654498 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 24401715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24401715 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22769066 — Surrogate Endpoint (SUR): Blood pressure
Study 8458531 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30832648 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26758193 — Surrogate Endpoint (SUR): Blood pressure
Study 16044078 — Predictive Biomarker (PRD): ITGB2 mRNA
Genes: ITGB2; CD18; MFI7
Study 16044078 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17498126 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17498126 — Surrogate Endpoint (SUR): Serum creatinine
Study 17498126 — Surrogate Endpoint (SUR): Blood pressure
Study 16177001 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7608283 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15804728 — Surrogate Endpoint (SUR): Bone mineral density
Study 7526098 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 12207762 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 22114906 — Surrogate Endpoint (SUR): Blood pressure
Study 19003983 — Predictive Biomarker (PRD): TOP2A mRNA
Genes: TOP2A; TOP2
Study 19003983 — Predictive Biomarker (PRD): ABCC1 mRNA
Genes: ABCC1; MRP; MRP1
Study 22132379 — Surrogate Endpoint (SUR): Blood pressure
Study 17078096 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30282639 — Surrogate Endpoint (SUR): Blood pressure
Study 22640829 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 19098116 — Surrogate Endpoint (SUR): Blood pressure
Study 12202123 — Predictive Biomarker (PRD): COMP mRNA
Genes: COMP
Study 1661490 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 16733277 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22303911 — Surrogate Endpoint (SUR): Blood pressure
Study 19914303 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 12140804 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2556172 — Surrogate Endpoint (SUR): Blood pressure
Study 25329451 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 25329451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25329451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25329451 — Safety Biomarker (SAF): Interleukin 1
Study 25329451 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 21157392 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11679387 — Surrogate Endpoint (SUR): Blood pressure
Study 21927920 — Surrogate Endpoint (SUR): Bone mineral density
Study 18842948 — Surrogate Endpoint (SUR): Blood pressure
Study 25971686 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23948623 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23948623 — Surrogate Endpoint (SUR): Blood pressure
Study 3225688 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3225688 — Surrogate Endpoint (SUR): Blood pressure
Study 25668198 — Surrogate Endpoint (SUR): Bone mineral density
Study 20513828 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1300984 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 1300984 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18420499 — Predictive Biomarker (PRD): Hormone receptor
Study 11778513 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9275365 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 9275365 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 30110719 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 24401930 — Surrogate Endpoint (SUR): Pathological complete response
Study 17617202 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 12414850 — Surrogate Endpoint (SUR): Bone mineral density
Study 10220494 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31756640 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ERCC2
Genes: MAG; EM9; MGC102762; MGC126218; MGC126219
Study 28818742 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 23450056 — Surrogate Endpoint (SUR): Bone mineral density
Study 8865916 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20697948 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 20697948 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 18606250 — Surrogate Endpoint (SUR): Blood pressure
Study 11886178 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10452749 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7256979 — Surrogate Endpoint (SUR): Blood pressure
Study 17174527 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 16680285 — Surrogate Endpoint (SUR): Blood pressure
Study 11478142 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 8859724 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 8859724 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31961420 — Surrogate Endpoint (SUR): Blood pressure
Study 27136744 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 27136744 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 27136744 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27136744 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17685853 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 17685853 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 21760549 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16775552 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 11524344 — Surrogate Endpoint (SUR): Blood pressure
Study 3423310 — Surrogate Endpoint (SUR): Blood pressure
Study 3423310 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28372335 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 18480688 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 11094013 — Surrogate Endpoint (SUR): Blood pressure
Study 1893647 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1893647 — Surrogate Endpoint (SUR): Blood pressure
Study 20664489 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 20664489 — Safety Biomarker (SAF): DRD2
Study 17172427 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 11081318 — Surrogate Endpoint (SUR): Blood pressure
Study 30908367 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30396975 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9076381 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 9076381 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 18098228 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18098228 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16579997 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 16579997 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 12690917 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12690917 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 12690917 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 12690917 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 11135795 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20813866 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 23878167 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22076596 — Surrogate Endpoint (SUR): Blood pressure
Study 15721999 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 16285179 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 29432379 — Surrogate Endpoint (SUR): Blood pressure
Study 18489783 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 10996579 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20424140 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 20424140 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8580688 — Predictive Biomarker (PRD): ALPK1 mRNA
Genes: ALPK1; KIAA1527; LAK
Study 8580688 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 21998259 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 21998259 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 20480225 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18705755 — Surrogate Endpoint (SUR): Blood pressure
Study 18705755 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7468946 — Surrogate Endpoint (SUR): Blood pressure
Study 6342641 — Surrogate Endpoint (SUR): Blood pressure
Study 16326298 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 27888608 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23419231 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28003203 — Surrogate Endpoint (SUR): Blood pressure
Study 24047919 — Surrogate Endpoint (SUR): Blood pressure
Study 24047919 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24047919 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18205185 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 18205185 — Surrogate Endpoint (SUR): Bone mineral density
Study 16443229 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 16443229 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study 16443229 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16443229 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 8630663 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22624697 — Surrogate Endpoint (SUR): Blood pressure
Study 20722555 — Surrogate Endpoint (SUR): Blood pressure
Study 18408611 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 18408611 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP