TrialPanorama/TrialPanorama-database huggingface dataset:
Study 24750799 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 24750799 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24750799 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 17057556 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 10919170 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 30078086 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 30078086 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29505772 — Surrogate Endpoint (SUR): Blood pressure
Study 29505772 — Surrogate Endpoint (SUR): Serum creatinine
Study 24420746 — Predictive Biomarker (PRD): SLCO1B1 mRNA
Genes: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6
Study 9012902 — Predictive Biomarker (PRD): PIP mRNA
Genes: PIP; GCDFP15; GPIP4
Study 7936810 — Predictive Biomarker (PRD): DHPS mRNA
Genes: DHPS; DS
Study 28663621 — Surrogate Endpoint (SUR): Blood pressure
Study 21970447 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15058039 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9360163 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30889827 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30889827 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30889827 — Safety Biomarker (SAF): BDNF
Study 30889827 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 29106772 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27528611 — Safety Biomarker (SAF): Hyaluronic acid
Study 20196969 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20196969 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22915617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22915617 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10341322 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 27830357 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27830357 — Safety Biomarker (SAF): IL-6 and IL-10
Study 17445350 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study 9728840 — Surrogate Endpoint (SUR): Blood pressure
Study 24228847 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12146728 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 10214759 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 21531237 — Surrogate Endpoint (SUR): Blood pressure
Study 9413851 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 9413851 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20646375 — Surrogate Endpoint (SUR): Serum calcium
Study 17640421 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9689265 — Surrogate Endpoint (SUR): Blood pressure
Study 2511726 — Surrogate Endpoint (SUR): Blood pressure
Study 31621668 — Surrogate Endpoint (SUR): Blood pressure
Study 9149675 — Surrogate Endpoint (SUR): Blood pressure
Study 30100404 — Surrogate Endpoint (SUR): Forced vital capacity
Study 24712563 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24712563 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9389292 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3030650 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 25564551 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 18522686 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15333385 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15333385 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 31888765 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23062408 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19450114 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 9703292 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 15714065 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 15714065 — Predictive Biomarker (PRD): DCX mRNA
Genes: DCX; DBCN; LISX
Study 11836040 — Surrogate Endpoint (SUR): Blood pressure
Study 8646826 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29205515 — Surrogate Endpoint (SUR): Blood pressure
Study 29205515 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16324022 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 11519066 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11519066 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 31656130 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31656130 — Surrogate Endpoint (SUR): Serum triglycerides
Study 19228530 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19228530 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23410564 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23410564 — Surrogate Endpoint (SUR): Blood pressure
Study 23410564 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19922017 — Surrogate Endpoint (SUR): Bone mineral density
Study 9416943 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1627436 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30782199 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 23622590 — Surrogate Endpoint (SUR): Serum creatinine
Study 21115860 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 11378011 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30280635 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 26536083 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 16159843 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 22875911 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 22875911 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 22875911 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 22875911 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYH11 mRNA
Genes: MYH11; KIAA0866
Study 15917061 — Surrogate Endpoint (SUR): Blood pressure
Study 14601352 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27452158 — Surrogate Endpoint (SUR): Blood pressure
Study 16996808 — Surrogate Endpoint (SUR): Blood pressure
Study 15623574 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study 12006323 — Surrogate Endpoint (SUR): Serum creatinine
Study 12006323 — Surrogate Endpoint (SUR): Blood pressure
Study 2214880 — Monitoring Biomarker (MOI): HBV DNA
Study 28592311 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 28592311 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28592311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28592311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28592311 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28592311 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 28592311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24248532 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 24248532 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24248532 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 22616615 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16841678 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15522554 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 11163295 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study 29214920 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 21284702 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 30808774 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30808774 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 30808774 — Predictive Biomarker (PRD): Tumor-infiltrating lymphocyte
Study 30808774 — Predictive Biomarker (PRD): Hormone receptor
Study 9141937 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 29662493 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 20980977 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 20980977 — Surrogate Endpoint (SUR): Serum creatinine
Study 18093273 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 18093273 — Surrogate Endpoint (SUR): Serum creatinine
Study 1315644 — Surrogate Endpoint (SUR): Blood pressure
Study 3910771 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 20439197 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 11300380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11300380 — Safety Biomarker (SAF): IL-6 and IL-10
Study 8510513 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28446441 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11082090 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9367703 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26391465 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 14693733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): SRD5A2 mRNA
Genes: SRD5A2
Study 14693733 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CYP17A1 mRNA
Genes: CYP17A1; CYP17; S17AH
Study 14693733 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 31373418 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31373418 — Surrogate Endpoint (SUR): Blood pressure
Study 24202408 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MHC class I polypeptide-related sequence A
Genes: MICA; PERB11.1
Study 16722027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16722027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16722027 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23827881 — Predictive Biomarker (PRD): MT1G mRNA
Genes: MT1G; MT1K; MT1M
Study 23827881 — Predictive Biomarker (PRD): MT2A mRNA
Genes: MT2A; CES1; MT2
Study 19873910 — Predictive Biomarker (PRD): KITLG mRNA
Genes: KITLG; MGF; SCF
Study 17032148 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 9479341 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 8789182 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 23580378 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study 11535508 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study 9759983 — Surrogate Endpoint (SUR): Blood pressure
Study 30741579 — Predictive Biomarker (PRD): TMEM54 mRNA
Genes: TMEM54; BCLP; CAC1
Study 18541571 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15780456 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 30590716 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28189123 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 28189123 — Surrogate Endpoint (SUR): Serum testosterone
Study 23378537 — Predictive Biomarker (PRD): Hormone receptor
Study 17325898 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 23286422 — Surrogate Endpoint (SUR): Blood pressure
Study 19074638 — Surrogate Endpoint (SUR): Serum triglycerides
Study 28934191 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 28934191 — Safety Biomarker (SAF): BDNF
Study 16958775 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26979312 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21593809 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 9706918 — Surrogate Endpoint (SUR): Blood pressure
Study 11337976 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 11337976 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2439456 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 2439456 — Surrogate Endpoint (SUR): Blood pressure
Study 19394618 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12939536 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 12939536 — Surrogate Endpoint (SUR): Bone mineral density
Study 25316559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18847584 — Predictive Biomarker (PRD): GCA mRNA
Genes: GCA; GCL
Study 16373904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16373904 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31415825 — Surrogate Endpoint (SUR): Blood pressure
Study 21992075 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 21992075 — Predictive Biomarker (PRD): Hormone receptor
Study 19090876 — Surrogate Endpoint (SUR): Blood pressure
Study 11023764 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 24684105 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 15808751 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 15808751 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 18391643 — Predictive Biomarker (PRD): CNP mRNA
Genes: CNP
Study 18391643 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 1767648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22716976 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17364552 — Predictive Biomarker (PRD): Hormone receptor
Study 12818406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12818406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17573446 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17573446 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 17573446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29649425 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study 29649425 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 28103829 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 26122235 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 26122235 — Predictive Biomarker (PRD): GYPC mRNA
Genes: GYPC; GLPC; GPC
Study 19419350 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 16765146 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 16765146 — Surrogate Endpoint (SUR): Blood pressure
Study 3250317 — Surrogate Endpoint (SUR): Blood pressure
Study 18359865 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 18359865 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 18359865 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15076235 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27620995 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 22574592 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9392310 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 23485887 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 17012299 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31096099 — Surrogate Endpoint (SUR): Serum creatinine
Study 26733479 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 15753530 — Predictive Biomarker (PRD): SLC30A1 mRNA
Genes: SLC30A1; ZNT1
Study 15753530 — Predictive Biomarker (PRD): SLC39A1 mRNA
Genes: SLC39A1; IRT1; ZIP1; ZIRTL; CGI-08; CGI-71
Study 15753530 — Predictive Biomarker (PRD): SLC39A4 mRNA
Genes: SLC39A4; ZIP4
Study 19308417 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study 27911869 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 26216378 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26216378 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study 12706932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12706932 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21543294 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27771800 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 27771800 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 20657084 — Surrogate Endpoint (SUR): Probing pocket depth
Study 11502918 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 22151005 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 17573581 — Surrogate Endpoint (SUR): Serum sodium
Study 21529775 — Predictive Biomarker (PRD): CST9 mRNA
Genes: CST9; CLM; CTES7A
Study 31050763 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19961638 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 11855773 — Surrogate Endpoint (SUR): Blood pressure
Study 7374 — Surrogate Endpoint (SUR): Blood pressure
Study 30911113 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 29185604 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29185604 — Safety Biomarker (SAF): Aminopeptidase N
Genes: ANPEP; APN; CD13; PEPN
Study 29185604 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23819226 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14740231 — Predictive Biomarker (PRD); Safety Biomarker (SAF): GSTP1
Genes: GSTP
Study 14740231 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 14740231 — Safety Biomarker (SAF): Glutathione S-transferase P
Genes: GSTP1; FAEES3; GST3
Study 10863964 — Safety Biomarker (SAF): Interleukin 1
Study 7968324 — Surrogate Endpoint (SUR): Blood pressure
Study 28963915 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 9811154 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9811154 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30890552 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9783191 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 9783191 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study 24163616 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 21373969 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 21373969 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 20228976 — Surrogate Endpoint (SUR): Probing pocket depth
Study 18525396 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 18525396 — Surrogate Endpoint (SUR): Serum creatinine
Study 18525396 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12353340 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 12353340 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10577635 — Surrogate Endpoint (SUR): Blood pressure
Study 21659488 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 21659488 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 21659488 — Predictive Biomarker (PRD): STAT5A mRNA
Genes: STAT5A; STAT5
Study 21659488 — Predictive Biomarker (PRD): MAPK3 mRNA
Genes: MAPK3; ERK1; PRKM3
Study 21659488 — Predictive Biomarker (PRD): SOCS3 mRNA
Genes: SOCS3; CIS3; SSI3
Study 21659488 — Predictive Biomarker (PRD): PTPN1 mRNA
Genes: PTPN1; PTP1B
Study 16508257 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C