TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT04603287 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04603287 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT04101331 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT03889015 — Surrogate Endpoint (SUR): Bacterial count
Study NCT02427100 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04226612 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00587054 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04421664 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02202265 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study NCT03118076 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00159718 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04377256 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01138306 — Predictive Biomarker (PRD): INPP5D mRNA
Genes: INPP5D; SHIP; SHIP1
Study NCT02039206 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study NCT04021368 — Predictive Biomarker (PRD): CDK8 mRNA
Genes: CDK8
Study NCT03752372 — Predictive Biomarker (PRD): IL10RA mRNA
Genes: IL10RA; IL10R
Study NCT04127110 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02091921 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study NCT02129933 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02129933 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04480593 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT04480593 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT04480593 — Predictive Biomarker (PRD): PAK1 mRNA
Genes: PAK1
Study NCT01933516 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01933516 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01376362 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT03351478 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02581124 — Predictive Biomarker (PRD); Safety Biomarker (SAF): ABCG2
Genes: EST157481; MXR; BCRP; ABCP; CD338
Study NCT00830804 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study NCT00686010 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT03515213 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study NCT04300790 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04300790 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT02923310 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02923310 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02923310 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00605072 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00605072 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01697501 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study NCT00521014 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01668381 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03365583 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT02272985 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04493138 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00124657 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04321031 — Predictive Biomarker (PRD): DGAT2 mRNA
Genes: DGAT2; HMFN1045; UNQ738/PRO1433
Study NCT00293241 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study NCT02527941 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02197065 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03437213 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT00160368 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03967275 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00331955 — Pharmacodynamic Biomarker (PDY): Histone acetylation
Study NCT04104373 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT02514746 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00288561 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00288561 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01800110 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01903733 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01903733 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00637377 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00498966 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00377455 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study NCT00188357 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00188357 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02885766 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02885766 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT04361331 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03030534 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04583761 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00599235 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT00599235 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02011529 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02024841 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT00781872 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01429389 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT02284230 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04499534 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT04499534 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT02866331 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02866331 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT04715828 — Surrogate Endpoint (SUR): Sperm parameters
Study NCT03884023 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study NCT02026518 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02026518 — Predictive Biomarker (PRD): GATA3 mRNA
Genes: GATA3
Study NCT02026518 — Predictive Biomarker (PRD): Forkhead box protein P3
Genes: FOXP3; IPEX; JM2
Study NCT02993120 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00298155 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT02156804 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT03702426 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03737890 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02964988 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study NCT02290951 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00045812 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01812122 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT02776735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03753074 — Monitoring Biomarker (MOI): HBV DNA
Study NCT04491708 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT04491708 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03027050 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study NCT02905916 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00903344 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01968928 — Predictive Biomarker (PRD): PKM mRNA
Genes: PKM; OIP3; PK2; PK3; PKM2
Study NCT01283945 — Predictive Biomarker (PRD): FGFR1 mRNA
Genes: FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR
Study NCT01283945 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study NCT01283945 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01283945 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT05524792 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT00310843 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT00310843 — Predictive Biomarker (PRD): SLCO1A2 mRNA
Genes: SLCO1A2; OATP; OATP1; OATP1A2; SLC21A3
Study NCT04059822 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02687932 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02627833 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT02320071 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03001739 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04304248 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT01992666 — Predictive Biomarker (PRD): TREX1 mRNA
Genes: TREX1
Study NCT01992666 — Predictive Biomarker (PRD): SAMHD1 mRNA
Genes: SAMHD1; MOP5
Study NCT01992666 — Predictive Biomarker (PRD): ACP5 mRNA
Genes: ACP5
Study NCT00460915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01475825 — Predictive Biomarker (PRD): FH mRNA
Genes: FH
Study NCT01475825 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02299648 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT01676441 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01874119 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03457740 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02671955 — Predictive Biomarker (PRD): VSIR mRNA
Genes: VSIR; C10orf54; SISP1; VISTA; PP2135; UNQ730/PRO1412
Study NCT02640690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01562145 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT03371225 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study NCT00562640 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT00562640 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03907787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01946646 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study NCT05318443 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00764426 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01787747 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT01167153 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04450212 — Predictive Biomarker (PRD): CYP4F2 mRNA
Genes: CYP4F2
Study NCT01676545 — Safety Biomarker (SAF): Interleukin 1
Study NCT04766983 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04766983 — Predictive Biomarker (PRD): EDNRA mRNA
Genes: EDNRA; ETA; ETRA
Study NCT01416350 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01416350 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study NCT01652404 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT03918291 — Safety Biomarker (SAF): BDNF
Study NCT04868071 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02644057 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00498849 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study NCT01173146 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03949543 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05325398 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT01505803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00091884 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01009918 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03238196 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT03701334 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03701334 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03701334 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00351819 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT06314997 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00560625 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00001908 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study NCT00001908 — Safety Biomarker (SAF): Th2 cell
Study NCT01136863 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01661309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT01631292 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT01877057 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT01877057 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT04493203 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04493203 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT00421408 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00000501 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00958425 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01184456 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01409408 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT01409408 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01737008 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01737008 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00431379 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT02363283 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study NCT04216550 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01100580 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00669032 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01345370 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT03820076 — Surrogate Endpoint (SUR): Bacterial count
Study NCT01065805 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT04804436 — Predictive Biomarker (PRD): HIPK2 mRNA
Genes: HIPK2
Study NCT04804436 — Safety Biomarker (SAF): HIPK2
Study NCT00803374 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT04365790 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04239170 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT05360225 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02193347 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT00952562 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03109067 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study NCT03109067 — Predictive Biomarker (PRD): ABCG1 mRNA
Genes: ABCG1; ABC8; WHT1
Study NCT03109067 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study NCT04126785 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04776824 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT03529019 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01641965 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT04628273 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT00771667 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05148169 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study NCT01151358 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01558505 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT00091897 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02103179 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02668744 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02393625 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01251757 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04401436 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03487458 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02408029 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT03091595 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study NCT02381548 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study NCT01917370 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04054882 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT03359954 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03359954 — Predictive Biomarker (PRD): Hormone receptor
Study NCT04275518 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT00123942 — Predictive Biomarker (PRD): CD2 mRNA
Genes: CD2; SRBC
Study NCT03749941 — Predictive Biomarker (PRD): SPN mRNA
Genes: SPN; CD43
Study NCT04279067 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT00879437 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT03092193 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT03092193 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT00498407 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT02899624 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study NCT01751997 — Predictive Biomarker (PRD): WT1 mRNA
Genes: WT1
Study NCT01751997 — Predictive Biomarker (PRD): BAALC mRNA
Genes: BAALC
Study NCT03796884 — Predictive Biomarker (PRD): GUCY2C mRNA
Genes: GUCY2C; GUC2C; STAR
Study NCT02223429 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT02757092 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT03571633 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02014103 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study NCT03543527 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03543527 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04357418 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study NCT03165500 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02445365 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02346812 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study NCT02098603 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04109482 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT04397926 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02368873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04095468 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00050011 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT00050011 — Predictive Biomarker (PRD): Hormone receptor
Study NCT00050011 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00309257 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00342043 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study NCT03823807 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04114825 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT01486329 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03523585 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03940521 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03940521 — Predictive Biomarker (PRD): FCGR2B
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study NCT01379937 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04325607 — Surrogate Endpoint (SUR): Bacterial count
Study NCT01690325 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04206943 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00085020 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00343109 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL