TrialPanorama/TrialPanorama-database huggingface dataset:
Study 21050565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12665498 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20349354 — Surrogate Endpoint (SUR): Bone mineral density
Study 19231581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7801580 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 7801580 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 28395549 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 26379068 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 31553457 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study 8480506 — Surrogate Endpoint (SUR): Blood pressure
Study 3321926 — Surrogate Endpoint (SUR): Blood pressure
Study 3321926 — Surrogate Endpoint (SUR): Serum calcium
Study 20162245 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 20610478 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 20610478 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 3288029 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24122883 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 4030048 — Surrogate Endpoint (SUR): Blood pressure
Study 8877724 — Predictive Biomarker (PRD): OSM mRNA
Genes: OSM
Study 24751920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 1614072 — Surrogate Endpoint (SUR): Blood pressure
Study 6599697 — Surrogate Endpoint (SUR): Blood pressure
Study 31250880 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study 31250880 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31250880 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31250880 — Predictive Biomarker (PRD): Hormone receptor
Study 28525302 — Surrogate Endpoint (SUR): Bone mineral density
Study 25575502 — Surrogate Endpoint (SUR): Blood pressure
Study 19321506 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 11738277 — Safety Biomarker (SAF): MTHFR
Study 11738277 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 15259895 — Monitoring Biomarker (MOI): HBV DNA
Study 28189188 — Surrogate Endpoint (SUR): Blood pressure
Study 19682100 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16619360 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 20587703 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18940401 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25351474 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17906853 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 12810429 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1511475 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1511475 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 1511475 — Surrogate Endpoint (SUR): Blood pressure
Study 29905977 — Surrogate Endpoint (SUR): Blood pressure
Study 2764271 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 31110103 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 31110103 — Surrogate Endpoint (SUR): Blood pressure
Study 18641035 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8354723 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 29150377 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18343265 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 22652371 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 25921600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25921600 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23358161 — Predictive Biomarker (PRD): EEF1A2 mRNA
Genes: EEF1A2; EEF1AL; STN
Study 18191483 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 17261575 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 11837468 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 3407893 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9509495 — Surrogate Endpoint (SUR): Serum sodium
Study 3065506 — Surrogate Endpoint (SUR): Blood pressure
Study 21398433 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 31090563 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 25723614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25723614 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9815725 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9815725 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16802555 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16802555 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25008579 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25008579 — Surrogate Endpoint (SUR): Blood pressure
Study 15709987 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30794101 — Predictive Biomarker (PRD): GFAP mRNA
Genes: GFAP
Study 19272686 — Safety Biomarker (SAF): MTHFR
Study 29753370 — Surrogate Endpoint (SUR): Serum potassium
Study 29753370 — Surrogate Endpoint (SUR): Blood pressure
Study 17181378 — Surrogate Endpoint (SUR): Bone mineral density
Study 17181378 — Surrogate Endpoint (SUR): Serum calcium
Study 23277434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 23277434 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 9915315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9915315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28807986 — Surrogate Endpoint (SUR): Blood pressure
Study 18328834 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 15733631 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 9084513 — Surrogate Endpoint (SUR): Blood pressure
Study 18077833 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15528874 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15528874 — Surrogate Endpoint (SUR): Blood pressure
Study 15463826 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15463826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31024649 — Surrogate Endpoint (SUR): Blood pressure
Study 28586395 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26474517 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26474517 — Predictive Biomarker (PRD): FLT1 mRNA
Genes: FLT1; FLT; FRT; VEGFR1
Study 16488958 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 18373318 — Surrogate Endpoint (SUR): Blood pressure
Study 8655293 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 435053 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30778742 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24638976 — Surrogate Endpoint (SUR): Blood pressure
Study 27681813 — Safety Biomarker (SAF): Hyaluronic acid
Study 23807157 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21075370 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 21075370 — Safety Biomarker (SAF): BDNF
Study 10886488 — Predictive Biomarker (PRD): HHEX mRNA
Genes: HHEX; HEX; PRH; PRHX
Study 8346832 — Surrogate Endpoint (SUR): Blood pressure
Study 29798249 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8856712 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 22192729 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 20184211 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 10619912 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 29119559 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 29119559 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 29119559 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15095653 — Surrogate Endpoint (SUR): Blood pressure
Study 29374733 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 29374733 — Predictive Biomarker (PRD): GPX1 mRNA
Genes: GPX1
Study 22211640 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 18541900 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 18541900 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 11807147 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 7669468 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 25578255 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11307743 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 9568470 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20886556 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study 18720880 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 16443423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12763175 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 12763175 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 10480191 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10480191 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16925684 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 11322745 — Safety Biomarker (SAF): DRD2
Study 9165504 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 8427853 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8427853 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 2887102 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2887102 — Surrogate Endpoint (SUR): Blood pressure
Study 27504637 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11574763 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 29741564 — Surrogate Endpoint (SUR): Blood pressure
Study 20856132 — Surrogate Endpoint (SUR): Blood pressure
Study 15598784 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 15598784 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study 15598784 — Safety Biomarker (SAF): TGFB1
Genes: CED; TGFbeta
Study 9270645 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9270645 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 3130221 — Surrogate Endpoint (SUR): Blood pressure
Study 31600749 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 31600749 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 28522646 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 23694782 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 16644323 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 12475575 — Surrogate Endpoint (SUR): Blood pressure
Study 9745423 — Surrogate Endpoint (SUR): Bone mineral density
Study 28073779 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 22332898 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 29339527 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 29339527 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 12085156 — Surrogate Endpoint (SUR): Bone mineral density
Study 25711952 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23043368 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 18781073 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 10865302 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 29574039 — Predictive Biomarker (PRD): FBP1 mRNA
Genes: FBP1; FBP
Study 16611719 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8617884 — Predictive Biomarker (PRD): CFTR
Genes: MRP7; ABC35; TNR-CFTR; dJ760C5.1; CFTR/MRP
Study 29361285 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11407868 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 7956628 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26718578 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26718578 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Interleukin 17
Genes: IL17A; CTLA8; IL17
Study 26035251 — Surrogate Endpoint (SUR): Blood pressure
Study 22412169 — Surrogate Endpoint (SUR): Blood pressure
Study 22412169 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22412169 — Surrogate Endpoint (SUR): Serum creatinine
Study 22412169 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11943418 — Surrogate Endpoint (SUR): Serum creatinine
Study 10356104 — Surrogate Endpoint (SUR): Blood pressure
Study 1954814 — Surrogate Endpoint (SUR): Blood pressure
Study 27765365 — Surrogate Endpoint (SUR): Blood pressure
Study 27765365 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27765365 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25563311 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 20477825 — Surrogate Endpoint (SUR): Serum sodium
Study 11908712 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study 23712056 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 11437028 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 30322392 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 11128879 — Predictive Biomarker (PRD): DDT mRNA
Genes: DDT
Study 3522159 — Surrogate Endpoint (SUR): Blood pressure
Study 3522159 — Surrogate Endpoint (SUR): Serum potassium
Study 25985726 — Safety Biomarker (SAF): miR-200a
Genes: MIR200A
Study 25985726 — Safety Biomarker (SAF): miR-155
Genes: MIR155
Study 23197844 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21233091 — Surrogate Endpoint (SUR): Blood pressure
Study 17130328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17130328 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12480972 — Surrogate Endpoint (SUR): Serum creatinine
Study 1609038 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 1609038 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 30205315 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15763286 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 15763286 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 7772359 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 758627 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 27801415 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 27801415 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 3288258 — Surrogate Endpoint (SUR): Serum calcium
Study 3288258 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 30184513 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study 15127203 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 2104626 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 31880734 — Surrogate Endpoint (SUR): Blood pressure
Study 23497506 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23497506 — Surrogate Endpoint (SUR): Blood pressure
Study 19124984 — Surrogate Endpoint (SUR): Blood pressure
Study 2643592 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study 30911753 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 22379908 — Predictive Biomarker (PRD): MBP mRNA
Genes: MBP
Study 22379908 — Surrogate Endpoint (SUR): Blood pressure
Study 8252687 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23137823 — Surrogate Endpoint (SUR): Blood pressure
Study 23137823 — Surrogate Endpoint (SUR): Serum triglycerides
Study 23137823 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8385164 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8385164 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 2908819 — Surrogate Endpoint (SUR): Blood pressure
Study 31904707 — Predictive Biomarker (PRD): SFPQ mRNA
Genes: SFPQ; PSF
Study 1683818 — Surrogate Endpoint (SUR): Blood pressure
Study 7121808 — Surrogate Endpoint (SUR): Blood pressure
Study 10357377 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7573097 — Surrogate Endpoint (SUR): Hematologic response
Study 12907329 — Surrogate Endpoint (SUR): Blood pressure
Study 10388649 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 29397092 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29397092 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18033323 — Predictive Biomarker (PRD): RAD51 mRNA
Genes: RAD51; RAD51A; RECA
Study 18033323 — Predictive Biomarker (PRD): XRCC3 mRNA
Genes: XRCC3
Study 18033323 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 11828042 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 11828042 — Predictive Biomarker (PRD): HGS mRNA
Genes: HGS; HRS
Study 7731622 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 28567691 — Predictive Biomarker (PRD): PYCARD mRNA
Genes: PYCARD; ASC; CARD5; TMS1
Study 21676011 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 19765496 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 11235719 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11235719 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 19788440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19788440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19788440 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19788440 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10096582 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30948335 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 25879572 — Surrogate Endpoint (SUR): Blood pressure
Study 25879572 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21342376 — Surrogate Endpoint (SUR): Serum testosterone
Study 9577354 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22104550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22104550 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22104550 — Surrogate Endpoint (SUR): Blood pressure
Study 16875929 — Predictive Biomarker (PRD): DCC mRNA
Genes: DCC; IGDCC1
Study 10720170 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1548998 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22009803 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9038595 — Surrogate Endpoint (SUR): Bone mineral density
Study 2892874 — Surrogate Endpoint (SUR): Blood pressure
Study 30020987 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 24554962 — Surrogate Endpoint (SUR): Blood pressure
Study 22854639 — Surrogate Endpoint (SUR): Blood pressure
Study 9041328 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27213613 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Immunoglobulin E
Study 23692706 — Surrogate Endpoint (SUR): Blood pressure
Study 7526126 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 25117722 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 23172749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23172749 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12953129 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 18201827 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16968874 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 9391998 — Surrogate Endpoint (SUR): Bone mineral density
Study 26427705 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 24174910 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21678045 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 18344635 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1