TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT02344004 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT02995954 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02995954 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01333748 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT01333748 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04066127 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study NCT02778269 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02148926 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study NCT00472108 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT03294811 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03294811 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04200521 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study NCT04200521 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study NCT04386369 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02787837 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study NCT02787837 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02787837 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02601664 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study NCT03367455 — Predictive Biomarker (PRD): KCNJ11 mRNA
Genes: KCNJ11
Study NCT03367455 — Surrogate Endpoint (SUR): Serum potassium
Study NCT06566781 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02628197 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT02628197 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00526669 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study NCT02333461 — Predictive Biomarker (PRD): DGAT1 mRNA
Genes: DGAT1; AGRP1; DGAT
Study NCT03803306 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02848131 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01463969 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study NCT03159416 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01983475 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04496492 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04496492 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04496492 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01122641 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT01335087 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02647099 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03637985 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01487109 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04494256 — Pharmacodynamic Biomarker (PDY): Ataxin-2
Genes: ATXN2; ATX2; SCA2; TNRC13
Study NCT03259230 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00339586 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02779699 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT02739295 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00079326 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02009397 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02870166 — Predictive Biomarker (PRD): SLC39A4 mRNA
Genes: SLC39A4; ZIP4
Study NCT02763787 — Predictive Biomarker (PRD): COMT mRNA
Genes: COMT
Study NCT02667587 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study NCT04212091 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02099851 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03726710 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03726710 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03617341 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00174096 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT00174096 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study NCT03207100 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04407585 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02656017 — Surrogate Endpoint (SUR): Total kidney volume
Study NCT03784443 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03784443 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00890487 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00002814 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03590444 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03590444 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04303455 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study NCT02154633 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT02154633 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04528212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03301207 — Predictive Biomarker (PRD): CYP2B6 mRNA
Genes: CYP2B6
Study NCT03301207 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00777946 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01802372 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02894723 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01762410 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT02470065 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT04790019 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03730636 — Monitoring Biomarker (MOI): Procalcitonin
Study NCT00136539 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00160706 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04197401 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02796066 — Predictive Biomarker (PRD): TSN mRNA
Genes: TSN
Study NCT01444833 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT00001331 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT00807651 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT00444899 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02077166 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT02468817 — Surrogate Endpoint (SUR): Serum calcium
Study NCT02198079 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT01884051 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT04598867 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study NCT02831803 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00435591 — Surrogate Endpoint (SUR): Serum sodium
Study NCT01038401 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01486212 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03377582 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04357535 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT04357535 — Predictive Biomarker (PRD): ACE2 mRNA
Genes: ACE2; UNQ868/PRO1885
Study NCT03597347 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT02272842 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT04078412 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT02872584 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02175134 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study NCT01296373 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04131413 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT00448279 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00559702 — Predictive Biomarker (PRD): MTR mRNA
Genes: MTR
Study NCT02192879 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04894760 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02523924 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02719587 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03507257 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study NCT00139191 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study NCT02557191 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00267826 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00267826 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04098211 — Predictive Biomarker (PRD): Tripeptidyl-peptidase I
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study NCT01594307 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04049799 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study NCT05059431 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT05059431 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT02340117 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT04004975 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study NCT04256577 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study NCT04256577 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00796731 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04315051 — Predictive Biomarker (PRD): DBI mRNA
Genes: DBI
Study NCT03081754 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03081754 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03081754 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study NCT01554774 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study NCT01554774 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01195662 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01195662 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04156113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02067117 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT00449553 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00449553 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02534038 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT03564977 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT03993821 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT04130542 — Predictive Biomarker (PRD): TNFRSF9 mRNA
Genes: TNFRSF9; CD137; ILA
Study NCT03144713 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03830073 — Predictive Biomarker (PRD): VDR mRNA
Genes: VDR; NR1I1
Study NCT00687973 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00906945 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT00906945 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study NCT00161291 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02519400 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT02519400 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT03994289 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT03179137 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02731794 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02681991 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02568735 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04575194 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01725906 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01079741 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study NCT04302441 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00201994 — Surrogate Endpoint (SUR): Serum sodium
Study NCT04320797 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02807025 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT02847078 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01319669 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT00407654 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04009668 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04009668 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT04009668 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study NCT04471519 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00837252 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT02948374 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01588496 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01588496 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02722733 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02688907 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT02688907 — Predictive Biomarker (PRD): CDKN2A mRNA
Genes: CDKN2A; CDKN2; MTS1
Study NCT02688907 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT02688907 — Pharmacodynamic Biomarker (PDY): Cyclin-dependent kinase 1
Genes: CDK1; CDC2; CDC28A; CDKN1; P34CDC2
Study NCT02688907 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT02688907 — Predictive Biomarker (PRD): WEE1 mRNA
Genes: WEE1
Study NCT00817362 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT06035289 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT04630613 — Predictive Biomarker (PRD): NOX4 mRNA
Genes: NOX4; RENOX
Study NCT00504361 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT00983931 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00767468 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT00900328 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT00900328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT00900328 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT01853826 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02741128 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02741128 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT01070030 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01414985 — Predictive Biomarker (PRD): Tripeptidyl-peptidase I
Genes: TPP1; CLN2; GIG1; UNQ267/PRO304
Study NCT01966471 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT04614311 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00172627 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT01839487 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study NCT01017484 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00589238 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03331601 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00594958 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT02613559 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03457038 — Predictive Biomarker (PRD): MBL2 mRNA
Genes: MBL2; COLEC1; MBL
Study NCT00036855 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT01794663 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study NCT01794663 — Predictive Biomarker (PRD): TLR2
Genes: TIL4; CD282
Study NCT01794663 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04473157 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02789254 — Predictive Biomarker (PRD): FLT3 mRNA
Genes: FLT3; CD135; FLK2; STK1
Study NCT00203476 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02705287 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT03478540 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT04539678 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT04433585 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT02703272 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT02703272 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT03005860 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02090959 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02980341 — Predictive Biomarker (PRD): ERBB3 mRNA
Genes: ERBB3; HER3
Study NCT04220697 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study NCT00624923 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01788189 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT02921035 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT03298360 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03298360 — Predictive Biomarker (PRD): FCGR2B
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study NCT03820596 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT03820596 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT02847377 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT02847377 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03648905 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04125732 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04125732 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT04641494 — Predictive Biomarker (PRD): HSPA1A mRNA
Genes: HSPA1A; HSP72; HSPA1; HSX70
Study NCT04641494 — Predictive Biomarker (PRD): HSPB1 mRNA
Genes: HSPB1; HSP27; HSP28
Study NCT02878681 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01029652 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03956823 — Predictive Biomarker (PRD): PPARA mRNA
Genes: PPARA; NR1C1; PPAR
Study NCT00169871 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01812551 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02625727 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT00692848 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT00692848 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00539162 — Predictive Biomarker (PRD): WAP four-disulfide core domain protein 2
Genes: WFDC2; HE4; WAP5
Study NCT02963610 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT03489863 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study NCT01990560 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02510781 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT04681911 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00120263 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT00784693 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT01501760 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00220753 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study NCT03467321 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT00866853 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study NCT00866853 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT00866853 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1