TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT01455012 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04305795 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04305795 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03022292 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01812200 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study NCT01812200 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study NCT03879629 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03150576 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT03732326 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02665416 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study NCT02665416 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03872427 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT03872427 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Nuclear factor erythroid 2-related factor 2
Genes: NFE2L2; NRF2
Study NCT03872427 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study NCT01499888 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT01538862 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT01672476 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00454168 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT02469116 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01750580 — Safety Biomarker (SAF): Cytotoxic T-lymphocyte protein 4
Genes: CTLA4; CD152
Study NCT00005631 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study NCT00344773 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00344773 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01884610 — Predictive Biomarker (PRD): CSF3 mRNA
Genes: CSF3; C17orf33; GCSF
Study NCT02093598 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study NCT02093598 — Predictive Biomarker (PRD): BAD mRNA
Genes: BAD; BBC6; BCL2L8
Study NCT02093598 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT02093598 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CTNNB1 mRNA
Genes: CTNNB1; CTNNB; OK/SW-cl.35; PRO2286
Study NCT02093598 — Predictive Biomarker (PRD): Microsatellite instability
Study NCT01628900 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study NCT01697072 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT03410576 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study NCT03410576 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT01755923 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01041924 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01388075 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study NCT04383561 — Predictive Biomarker (PRD): Leucine-rich alpha-2-glycoprotein
Genes: LRG1; LRG
Study NCT04383561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00197145 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02147223 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04805203 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01878201 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03375541 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02684227 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01855295 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01855295 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT01855295 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03594097 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03594097 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03594097 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT03594097 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03795207 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03795207 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study NCT01023087 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00843921 — Surrogate Endpoint (SUR): Plasma ammonia
Study NCT00971347 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02018458 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02694146 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01718756 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01564303 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT01450410 — Predictive Biomarker (PRD): LCAT mRNA
Genes: LCAT
Study NCT02032147 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT02885870 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT00196586 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02233010 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study NCT02233010 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT02059759 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02059759 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT02059759 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03294135 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT00001893 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03805022 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT01840293 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01840293 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01840293 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT03782428 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00058526 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03539835 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT05261867 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02011620 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04732975 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00806884 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02501980 — Predictive Biomarker (PRD): AFP mRNA
Genes: AFP; HPAFP
Study NCT02202447 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT03833089 — Surrogate Endpoint (SUR): Serum potassium
Study NCT02311569 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study NCT04116918 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03364296 — Predictive Biomarker (PRD): PRDX1 mRNA
Genes: PRDX1; PAGA; PAGB; TDPX2
Study NCT01852448 — Predictive Biomarker (PRD): TCF7L2 mRNA
Genes: TCF7L2; TCF4
Study NCT03774940 — Safety Biomarker (SAF): Neutrophil to lymphocyte
Study NCT03774940 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT03317171 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT01274624 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02086942 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study NCT05723016 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00736801 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT00736801 — Safety Biomarker (SAF): BDNF
Study NCT02052921 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT02180334 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study NCT02180334 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT03025828 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study NCT00850395 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT02361255 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT02361255 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT02739269 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01914224 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01658137 — Predictive Biomarker (PRD): CDKN2B-AS1
Study NCT01658137 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02822131 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02822131 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study NCT01068509 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study NCT00531076 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03647111 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT01173029 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01341886 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT04716023 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02519712 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT04397809 — Predictive Biomarker (PRD): TLR2 mRNA
Genes: TLR2; TIL4
Study NCT04397809 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02046850 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study NCT00340600 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study NCT02523768 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study NCT06427278 — Predictive Biomarker (PRD): HMGA2 mRNA
Genes: HMGA2; HMGIC
Study NCT06427278 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-143
Genes: MIR143
Study NCT02479581 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT04424056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT04424056 — Predictive Biomarker (PRD): NLRP3 mRNA
Genes: NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Study NCT04424056 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT01395329 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00525824 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT00593853 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study NCT00642174 — Predictive Biomarker (PRD): VASP mRNA
Genes: VASP
Study NCT04525261 — Predictive Biomarker (PRD): RPE65 mRNA
Genes: RPE65
Study NCT00881192 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02705677 — Predictive Biomarker (PRD): MECP2 mRNA
Genes: MECP2
Study NCT02705677 — Predictive Biomarker (PRD): Cyclin-dependent kinase-like 5
Genes: CDKL5; STK9
Study NCT02705677 — Predictive Biomarker (PRD): FOXG1 mRNA
Genes: FOXG1; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; FOXG1A; FOXG1B; FOXG1C
Study NCT03311503 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT01803178 — Surrogate Endpoint (SUR): Blood pressure
Study NCT06184412 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT06184412 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study NCT06184412 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study NCT02806050 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study NCT02806050 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02986620 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study NCT02986620 — Predictive Biomarker (PRD): IDH2 mRNA
Genes: IDH2
Study NCT04216875 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03892083 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study NCT03302728 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT03118128 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT03118128 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study NCT03176472 — Predictive Biomarker (PRD): HDAC6 mRNA
Genes: HDAC6; KIAA0901; JM21
Study NCT03777709 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00590824 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT00380029 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00006347 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02850263 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02850263 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT03163693 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT01395121 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study NCT02243878 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00448071 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00445848 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02280174 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02280174 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study NCT00659217 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT00004374 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study NCT00779012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT02378194 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00323973 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03301194 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00048542 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT06158191 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01817725 — Monitoring Biomarker (MOI): HBV DNA
Study NCT01508780 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01197690 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT03047109 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00286767 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02419131 — Predictive Biomarker (PRD): PTS mRNA
Genes: PTS
Study NCT00081614 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00081614 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02441140 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT03552575 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03552575 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT00227318 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01691014 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01380743 — Safety Biomarker (SAF): Lysosomal alpha-glucosidase
Genes: GAA
Study NCT04213456 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT00579826 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study NCT01219036 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01389401 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT02000375 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02000375 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00793338 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04237428 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT00753116 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02319005 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study NCT00801125 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04372602 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03463889 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT01283399 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04371822 — Safety Biomarker (SAF): Reactive oxygen species
Study NCT02151526 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00847444 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT00847444 — Predictive Biomarker (PRD): Hormone receptor
Study NCT03036345 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02403908 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT02403908 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT04209114 — Predictive Biomarker (PRD): NKTR mRNA
Genes: NKTR
Study NCT02129478 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02088502 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT00448162 — Predictive Biomarker (PRD): SCNN1G mRNA
Genes: SCNN1G
Study NCT02442778 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study NCT02242851 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02264002 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03546751 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-210
Genes: MIR210
Study NCT00788827 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02800356 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01823783 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study NCT02660320 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01644175 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study NCT01644175 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03532932 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study NCT00497328 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT04684147 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01838642 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study NCT01991002 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00001877 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04118309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT04118309 — Predictive Biomarker (PRD): IL6
Genes: IL-6; BSF2; HGF; HSF
Study NCT04118309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00451035 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00451035 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT00300482 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT04008446 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study NCT00374712 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study NCT03672682 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT03672682 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study NCT03672682 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03141567 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03141567 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00525629 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT00256919 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01852266 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04657497 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04304170 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT04382248 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT04091984 — Surrogate Endpoint (SUR): Serum creatinine
Study NCT03589365 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02463032 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT02463032 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT02404415 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study NCT04853225 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study NCT04853225 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00573027 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT03726177 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study NCT00003739 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03012100 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03012100 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT02268409 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01898104 — Pharmacodynamic Biomarker (PDY): Valproic acid
Study NCT00363974 — Predictive Biomarker (PRD): XIAP mRNA
Genes: XIAP; API3; BIRC4; IAP3