TrialPanorama/TrialPanorama-database huggingface dataset:
Study 11783309 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11783309 — Surrogate Endpoint (SUR): Serum creatinine
Study 27927602 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27131642 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 27131642 — Surrogate Endpoint (SUR): Blood pressure
Study 22394170 — Surrogate Endpoint (SUR): Serum testosterone
Study 19236730 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 19236730 — Safety Biomarker (SAF): BDNF
Study 16266300 — Surrogate Endpoint (SUR): Blood pressure
Study 23507858 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 21838823 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21838823 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 21838823 — Surrogate Endpoint (SUR): Blood pressure
Study 2182891 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 2182891 — Predictive Biomarker (PRD): CD9 mRNA
Genes: CD9; MIC3; TSPAN29; GIG2
Study 2182891 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 7010382 — Surrogate Endpoint (SUR): Blood pressure
Study 27236654 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31338563 — Surrogate Endpoint (SUR): Bone mineral density
Study 9398701 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 9398701 — Surrogate Endpoint (SUR): Serum testosterone
Study 28642308 — Surrogate Endpoint (SUR): Forced vital capacity
Study 23551727 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23551727 — Surrogate Endpoint (SUR): Blood pressure
Study 23551727 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 27518195 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 23406757 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23406757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23406757 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23406757 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 15755765 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26908741 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28394521 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26835147 — Surrogate Endpoint (SUR): Serum creatinine
Study 10215943 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 7529482 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 1706665 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 1706665 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 16776048 — Surrogate Endpoint (SUR): Blood pressure
Study 28830083 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28830083 — Surrogate Endpoint (SUR): Serum creatinine
Study 23848141 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 18279739 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 18279739 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17157119 — Surrogate Endpoint (SUR): Blood pressure
Study 12925319 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21873668 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 11417951 — Surrogate Endpoint (SUR): Blood pressure
Study 7544967 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 21636711 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 9162622 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9162622 — Predictive Biomarker (PRD): CRH mRNA
Genes: CRH
Study 31800931 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28418398 — Predictive Biomarker (PRD): OXTR mRNA
Genes: OXTR
Study 17349080 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17349080 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9396883 — Surrogate Endpoint (SUR): Blood pressure
Study 7911290 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9715761 — Surrogate Endpoint (SUR): Blood pressure
Study 7873290 — Surrogate Endpoint (SUR): Bone mineral density
Study 23481448 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 10833065 — Predictive Biomarker (PRD): AOX1 mRNA
Genes: AOX1; AO
Study 10833065 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 22882579 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 25318924 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 17943541 — Surrogate Endpoint (SUR): Blood pressure
Study 11717654 — Surrogate Endpoint (SUR): Bone mineral density
Study 30357360 — Surrogate Endpoint (SUR): Serum potassium
Study 27678430 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 27678430 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 27678430 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 23437399 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8314291 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31501920 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28832288 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23165913 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19901110 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 19901110 — Predictive Biomarker (PRD): IDH1 mRNA
Genes: IDH1; PICD
Study 16546486 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16546486 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16546486 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17384344 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 2030596 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 29074595 — Predictive Biomarker (PRD): JAK1 mRNA
Genes: JAK1; JAK1A; JAK1B
Study 29074595 — Predictive Biomarker (PRD): CALR mRNA
Genes: CALR; CRTC
Study 26365936 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 17301218 — Pharmacodynamic Biomarker (PDY): Stromal cell-derived factor 1
Genes: CXCL12; SDF1; SDF1A; SDF1B
Study 17301218 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17301218 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 8115156 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 25867399 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 25867399 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17299078 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 7870278 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 7870278 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 7870278 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 31012599 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 11089744 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 8462386 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8462386 — Surrogate Endpoint (SUR): Blood pressure
Study 2939220 — Surrogate Endpoint (SUR): Blood pressure
Study 29648488 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 27458223 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 15198156 — Surrogate Endpoint (SUR): Serum sodium
Study 24399647 — Pharmacodynamic Biomarker (PDY): Ataxin-3
Genes: ATXN3; ATX3; MJD; MJD1; SCA3
Study 25204553 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 8630380 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30232083 — Predictive Biomarker (PRD): STIL mRNA
Genes: STIL; SIL
Study 30232083 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 30232083 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30232083 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study 2170820 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2170820 — Surrogate Endpoint (SUR): Blood pressure
Study 25530275 — Surrogate Endpoint (SUR): Blood pressure
Study 24197662 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20722559 — Surrogate Endpoint (SUR): Serum creatinine
Study 15793048 — Surrogate Endpoint (SUR): Blood pressure
Study 7721614 — Surrogate Endpoint (SUR): Serum testosterone
Study 2047898 — Surrogate Endpoint (SUR): Blood pressure
Study 16438453 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 27491377 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17827461 — Predictive Biomarker (PRD): GCNT2 mRNA
Genes: GCNT2; GCNT5; II; NACGT1
Study 26897518 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 28169875 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28169875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 28169875 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9817266 — Predictive Biomarker (PRD): CA10 mRNA
Genes: CA10; hucep-15; UNQ533/PRO1076
Study 3582314 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3294618 — Surrogate Endpoint (SUR): Blood pressure
Study 19900070 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 15451915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16810076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11465619 — Surrogate Endpoint (SUR): Blood pressure
Study 2196144 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2196144 — Surrogate Endpoint (SUR): Blood pressure
Study 18565951 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 8522064 — Surrogate Endpoint (SUR): Blood pressure
Study 2859782 — Surrogate Endpoint (SUR): Blood pressure
Study 30051198 — Predictive Biomarker (PRD): SSTR5 mRNA
Genes: SSTR5
Study 18582370 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 1346558 — Surrogate Endpoint (SUR): Blood pressure
Study 6383990 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 10389558 — Surrogate Endpoint (SUR): Blood pressure
Study 1900007 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30255418 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 24881993 — Surrogate Endpoint (SUR): Blood pressure
Study 18398278 — Surrogate Endpoint (SUR): Blood pressure
Study 8638792 — Surrogate Endpoint (SUR): Blood pressure
Study 29072815 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27989874 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11505809 — Safety Biomarker (SAF): Reactive oxygen species
Study 11505809 — Surrogate Endpoint (SUR): Sperm parameters
Study 2792164 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 31802120 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 28333997 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 10999263 — Predictive Biomarker (PRD): MIF mRNA
Genes: MIF; GLIF; MMIF
Study 22353811 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 22353811 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22353811 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 22353811 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22353811 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 17420344 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16390748 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 16390748 — Predictive Biomarker (PRD): SMPD1 mRNA
Genes: SMPD1; ASM
Study 28536029 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28536029 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 25492271 — Predictive Biomarker (PRD): Liver iron
Study 22885164 — Predictive Biomarker (PRD): FCGR3A mRNA
Genes: FCGR3A; CD16A; FCG3; FCGR3; IGFR3
Study 22885164 — Predictive Biomarker (PRD): FCGR2A mRNA
Genes: FCGR2A; CD32; FCG2; FCGR2A1; IGFR2
Study 18335394 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 2288835 — Surrogate Endpoint (SUR): Blood pressure
Study 30608620 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 30608620 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15119693 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11766367 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 11766367 — Surrogate Endpoint (SUR): Serum testosterone
Study 9489910 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9489910 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27903675 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27903675 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 27903675 — Predictive Biomarker (PRD): Hormone receptor
Study 21177797 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 20039931 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 20039931 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 20039931 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20395096 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 18555812 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 18555812 — Surrogate Endpoint (SUR): Bone mineral density
Study 18555812 — Surrogate Endpoint (SUR): Serum calcium
Study 16003231 — Surrogate Endpoint (SUR): Serum creatinine
Study 12484508 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12484508 — Surrogate Endpoint (SUR): Blood pressure
Study 12484508 — Surrogate Endpoint (SUR): Serum potassium
Study 29548945 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29548945 — Surrogate Endpoint (SUR): Blood pressure
Study 29548945 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29548945 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9649261 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 28554908 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 10680096 — Surrogate Endpoint (SUR): Forced vital capacity
Study 8409786 — Predictive Biomarker (PRD): C6 mRNA
Genes: C6
Study 31736357 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 7841660 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 30029486 — Surrogate Endpoint (SUR): Blood pressure
Study 25703666 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25703666 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 10822283 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10822283 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10822283 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22943199 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22943199 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 22943199 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20691042 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 6188917 — Surrogate Endpoint (SUR): Blood pressure
Study 26759975 — Predictive Biomarker (PRD): RRAD mRNA
Genes: RRAD; RAD
Study 9740606 — Surrogate Endpoint (SUR): Blood pressure
Study 29246725 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 26707868 — Surrogate Endpoint (SUR): Bone mineral density
Study 22715739 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 19671263 — Surrogate Endpoint (SUR): Blood pressure
Study 17576400 — Surrogate Endpoint (SUR): Bone mineral density
Study 10813372 — Surrogate Endpoint (SUR): Blood pressure
Study 8829885 — Surrogate Endpoint (SUR): Blood pressure
Study 6332895 — Surrogate Endpoint (SUR): Serum calcium
Study 23958115 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17884342 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17884342 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17884342 — Surrogate Endpoint (SUR): Blood pressure
Study 14562994 — Surrogate Endpoint (SUR): Bone mineral density
Study 6367863 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 29039254 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 17915406 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15043514 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27321772 — Surrogate Endpoint (SUR): Blood pressure
Study 7759785 — Predictive Biomarker (PRD): OCA2 mRNA
Genes: OCA2; D15S12; P
Study 21910341 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 19822977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16986348 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16986348 — Predictive Biomarker (PRD): Hormone receptor
Study 11019424 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 29685013 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16393327 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16393327 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 16393327 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 14652007 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 8841157 — Surrogate Endpoint (SUR): Blood pressure
Study 21040693 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 2349956 — Surrogate Endpoint (SUR): Blood pressure
Study 2349956 — Surrogate Endpoint (SUR): Serum creatinine
Study 31544469 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 1163095 — Predictive Biomarker (PRD): HBE1 mRNA
Genes: HBE1; HBE
Study 18676982 — Surrogate Endpoint (SUR): Blood pressure
Study 26428281 — Surrogate Endpoint (SUR): Blood pressure
Study 22550054 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22550054 — Surrogate Endpoint (SUR): Blood pressure
Study 30977312 — Monitoring Biomarker (MOI): Procalcitonin
Study 23735181 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 15502727 — Surrogate Endpoint (SUR): Bone mineral density
Study 30841655 — Surrogate Endpoint (SUR): Blood pressure
Study 12062320 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 7878170 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 31029921 — Predictive Biomarker (PRD): ADIPOQ mRNA
Genes: ADIPOQ; ACDC; ACRP30; APM1; GBP28
Study 31029921 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10741623 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 27355231 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 29777264 — Surrogate Endpoint (SUR): Serum creatinine
Study 20859551 — Surrogate Endpoint (SUR): Blood pressure
Study 17409842 — Surrogate Endpoint (SUR): Pathological complete response
Study 12854835 — Surrogate Endpoint (SUR): Bone mineral density
Study 12854835 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10795771 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 8642191 — Surrogate Endpoint (SUR): Blood pressure
Study 24866574 — Predictive Biomarker (PRD): IGF1 mRNA
Genes: IGF1; IBP1
Study 18557665 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 18557665 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 2149674 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2149674 — Surrogate Endpoint (SUR): Blood pressure
Study 7025264 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22027686 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17530112 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 11148914 — Predictive Biomarker (PRD): UBXN11 mRNA
Genes: UBXN11; SOC; UBXD5; PP2243
Study 10636373 — Surrogate Endpoint (SUR): Blood pressure
Study 28544580 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 25338187 — Predictive Biomarker (PRD): PGD mRNA
Genes: PGD; PGDH
Study 2176795 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 2176795 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 30853262 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID