TrialPanorama/TrialPanorama-database huggingface dataset:
Study 6938013 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 28880609 — Surrogate Endpoint (SUR): Blood pressure
Study 18438718 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 18438718 — Surrogate Endpoint (SUR): Serum creatinine
Study 11314834 — Surrogate Endpoint (SUR): Blood pressure
Study 9388088 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19515542 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 24895339 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 24895339 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20833266 — Surrogate Endpoint (SUR): Serum creatinine
Study 25626066 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 9924466 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3041248 — Surrogate Endpoint (SUR): Bone mineral density
Study 3041248 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 23652778 — Surrogate Endpoint (SUR): Serum creatinine
Study 23652778 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19074543 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25733317 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 25733317 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 11373411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11373411 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 3319111 — Surrogate Endpoint (SUR): Blood pressure
Study 24737678 — Safety Biomarker (SAF): Thiopurine S-methyltransferase
Genes: TPMT
Study 11429337 — Surrogate Endpoint (SUR): Blood pressure
Study 9531030 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 9531030 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30472196 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24968500 — Surrogate Endpoint (SUR): Blood pressure
Study 16520405 — Surrogate Endpoint (SUR): Blood pressure
Study 24312450 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20299470 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 3932077 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 3932077 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 26642301 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9287967 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 21692299 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 3739357 — Surrogate Endpoint (SUR): Blood pressure
Study 11470697 — Surrogate Endpoint (SUR): Blood pressure
Study 7921444 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20473630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20473630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 20305926 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 20305926 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 17985505 — Surrogate Endpoint (SUR): Blood pressure
Study 23182947 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 15809819 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 11179831 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 16598851 — Pharmacodynamic Biomarker (PDY): 5'-AMP-activated protein kinase subunit beta-1
Genes: PRKAB1; AMPK
Study 8304709 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 23591255 — Surrogate Endpoint (SUR): Blood pressure
Study 10912543 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10912543 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10912543 — Surrogate Endpoint (SUR): Bone mineral density
Study 8793024 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 6228459 — Predictive Biomarker (PRD): CLYBL mRNA
Genes: CLYBL; CLB
Study 26332605 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9769871 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 6786115 — Surrogate Endpoint (SUR): Blood pressure
Study 22995971 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 11851660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 11851660 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2965227 — Surrogate Endpoint (SUR): Blood pressure
Study 31955619 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12161047 — Surrogate Endpoint (SUR): Bone mineral density
Study 6393417 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31536101 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 11932276 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9795409 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 26072330 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 16504645 — Surrogate Endpoint (SUR): Blood pressure
Study 16504645 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16504645 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 15246125 — Predictive Biomarker (PRD): RET mRNA
Genes: RET; CDHF12; CDHR16; PTC; RET51
Study 8358980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27167103 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24309322 — Predictive Biomarker (PRD): PCDH10 mRNA
Genes: PCDH10; KIAA1400
Study 24309322 — Predictive Biomarker (PRD): SPARC mRNA
Genes: SPARC; ON
Study 24309322 — Predictive Biomarker (PRD): UCHL1 mRNA
Genes: UCHL1
Study 24309322 — Predictive Biomarker (PRD): PCDH10
Genes: OL-PCDH; KIAA1400
Study 18037940 — Predictive Biomarker (PRD): HDC mRNA
Genes: HDC
Study 10390385 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31368057 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 19534023 — Surrogate Endpoint (SUR): Blood pressure
Study 17024220 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9643274 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9643274 — Surrogate Endpoint (SUR): Blood pressure
Study 9643274 — Surrogate Endpoint (SUR): Serum uric acid
Study 3414729 — Surrogate Endpoint (SUR): Blood pressure
Study 28606731 — Surrogate Endpoint (SUR): Blood pressure
Study 17881183 — Predictive Biomarker (PRD): Hormone receptor
Study 12213869 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9810030 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9810030 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 2667311 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2667311 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 2667311 — Surrogate Endpoint (SUR): Blood pressure
Study 24152981 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 15246460 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 11734428 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 7695928 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30482135 — Surrogate Endpoint (SUR): Blood pressure
Study 28225050 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 25166221 — Surrogate Endpoint (SUR): Urine free cortisol
Study 27765726 — Predictive Biomarker (PRD): POU2F1 mRNA
Genes: POU2F1; OCT1; OTF1
Study 21987386 — Surrogate Endpoint (SUR): Bone mineral density
Study 18824714 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 18824714 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 11874164 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26214887 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 23953056 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 20687305 — Predictive Biomarker (PRD): AGA mRNA
Genes: AGA
Study 19090877 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19090877 — Surrogate Endpoint (SUR): Blood pressure
Study 9076210 — Surrogate Endpoint (SUR): Blood pressure
Study 26111104 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 26111104 — Predictive Biomarker (PRD): Hormone receptor
Study 21246188 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 19906504 — Surrogate Endpoint (SUR): Blood pressure
Study 25711323 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8625134 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23348071 — Surrogate Endpoint (SUR): Blood pressure
Study 19147457 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 16490090 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 26619202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26619202 — Surrogate Endpoint (SUR): Blood pressure
Study 23871259 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 11753267 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 23098170 — Surrogate Endpoint (SUR): Blood pressure
Study 6828614 — Surrogate Endpoint (SUR): Blood pressure
Study 16822563 — Surrogate Endpoint (SUR): Blood pressure
Study 16249527 — Surrogate Endpoint (SUR): Blood pressure
Study 11878059 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 11878059 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11878059 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29601904 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 18296554 — Surrogate Endpoint (SUR): Serum creatinine
Study 9225069 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 27245042 — Surrogate Endpoint (SUR): Blood pressure
Study 16715189 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 15278206 — Predictive Biomarker (PRD): CNR1 mRNA
Genes: CNR1; CNR
Study 29643323 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 9267667 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-A
Study 12809965 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11182393 — Predictive Biomarker (PRD): SLN mRNA
Genes: SLN
Study 323023 — Surrogate Endpoint (SUR): Blood pressure
Study 22551950 — Predictive Biomarker (PRD): PNPLA2 mRNA
Genes: PNPLA2; ATGL; FP17548
Study 22551950 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 10521742 — Surrogate Endpoint (SUR): Blood pressure
Study 29138226 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 29138226 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25060690 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 10516540 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 24359456 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 24359456 — Predictive Biomarker (PRD): FTO mRNA
Genes: FTO; KIAA1752
Study 24359456 — Surrogate Endpoint (SUR): Blood pressure
Study 19786805 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 19786805 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study 17442226 — Surrogate Endpoint (SUR): Blood pressure
Study 9689424 — Surrogate Endpoint (SUR): Blood pressure
Study 25594355 — Safety Biomarker (SAF): Hyaluronic acid
Study 16514482 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 22173570 — Surrogate Endpoint (SUR): Blood pressure
Study 19906800 — Surrogate Endpoint (SUR): Blood pressure
Study 2792112 — Surrogate Endpoint (SUR): Blood pressure
Study 29153546 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 29153546 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9808550 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23154577 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21632504 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 17101607 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9203190 — Surrogate Endpoint (SUR): Blood pressure
Study 24598116 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 12575587 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 12575587 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11747061 — Surrogate Endpoint (SUR): Blood pressure
Study 28287413 — Predictive Biomarker (PRD): GHR mRNA
Genes: GHR
Study 28287413 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 24483106 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19903376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19903376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19903376 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 15491387 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15491387 — Surrogate Endpoint (SUR): Blood pressure
Study 6137231 — Surrogate Endpoint (SUR): Blood pressure
Study 28902116 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28902116 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 30591380 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26228536 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 21982411 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 21982411 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 11029965 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 11029965 — Safety Biomarker (SAF): Cytochrome c
Study 9095122 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 29128682 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 24022270 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 24022270 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 8931343 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 3956056 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 3956056 — Surrogate Endpoint (SUR): Blood pressure
Study 27681755 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 22992240 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 27362956 — Surrogate Endpoint (SUR): Blood pressure
Study 25230867 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19291790 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 16218176 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12117728 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12117728 — Surrogate Endpoint (SUR): Serum testosterone
Study 388053 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 15183620 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 20880282 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 20880282 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11340101 — Surrogate Endpoint (SUR): Blood pressure
Study 15639694 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15639694 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8938539 — Monitoring Biomarker (MOI): HBV DNA
Study 3086024 — Safety Biomarker (SAF): 51Cr-EDTA
Study 3419838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30817467 — Surrogate Endpoint (SUR): Serum uric acid
Study 30817467 — Surrogate Endpoint (SUR): Blood pressure
Study 19131065 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HCAR3 mRNA
Genes: HCAR3; GPR109B; HCA3; HM74B; NIACR2
Study 19131065 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 19131065 — Predictive Biomarker (PRD): FASN mRNA
Genes: FASN; FAS
Study 9522320 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 27806875 — Monitoring Biomarker (MOI): IL4 mRNA
Genes: IL4
Study 27806875 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 16036498 — Surrogate Endpoint (SUR): Blood pressure
Study 18028738 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 7981575 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12944727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8846745 — Surrogate Endpoint (SUR): Blood pressure
Study 31894843 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27470569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 27470569 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 17003842 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study 30124753 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30124753 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 24249722 — Surrogate Endpoint (SUR): Blood pressure
Study 24249722 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25205641 — Surrogate Endpoint (SUR): Blood pressure
Study 26756107 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26756107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15886473 — Safety Biomarker (SAF): Hyaluronic acid
Study 12070557 — Surrogate Endpoint (SUR): Blood pressure
Study 12070557 — Surrogate Endpoint (SUR): Serum sodium
Study 2193993 — Surrogate Endpoint (SUR): Blood pressure
Study 2193993 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 30954691 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30954691 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30954691 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 30954691 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 27737489 — Surrogate Endpoint (SUR): Blood pressure
Study 9446253 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 8323356 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 26098483 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26098483 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20182424 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 11018854 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11018854 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 3016439 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 27506771 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 27506771 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12674587 — Surrogate Endpoint (SUR): Blood pressure
Study 10365740 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 25077100 — Surrogate Endpoint (SUR): Blood pressure
Study 29552010 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29552010 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29552010 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 12355999 — Surrogate Endpoint (SUR): Blood pressure
Study 6416805 — Surrogate Endpoint (SUR): Blood pressure
Study 26045831 — Monitoring Biomarker (MOI): Heme oxygenase 1
Genes: HMOX1; HO; HO1
Study 26045831 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26045831 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 23555741 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9105824 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 9105824 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9105824 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 28974520 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 21324135 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7241426 — Pharmacodynamic Biomarker (PDY): Salivary secretion
Study 26604719 — Predictive Biomarker (PRD): FBLN5 mRNA
Genes: FBLN5; DANCE; UNQ184/PRO210
Study 7046774 — Surrogate Endpoint (SUR): Blood pressure
Study 26255456 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21692846 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 19650984 — Surrogate Endpoint (SUR): Blood pressure
Study 11292409 — Surrogate Endpoint (SUR): Serum creatinine
Study 9030876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8292845 — Surrogate Endpoint (SUR): Serum calcium
Study 28107143 — Predictive Biomarker (PRD): Exhaled nitric oxide