TrialPanorama/TrialPanorama-database huggingface dataset:
Study 30323863 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Neutrophil gelatinase-associated lipocalin
Genes: LCN2; HNL; NGAL
Study 30324541 — Predictive Biomarker (PRD): GAST mRNA
Genes: GAST; GAS
Study 30325463 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30325463 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 30325463 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30325779 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30325779 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30326728 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study 30327731 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 30333224 — Predictive Biomarker (PRD): SYK mRNA
Genes: SYK
Study 30333892 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30334093 — Surrogate Endpoint (SUR): Bone mineral density
Study 30334387 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 30334521 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 30334909 — Predictive Biomarker (PRD): CYP1B1 mRNA
Genes: CYP1B1
Study 30334909 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MRP2
Genes: ABCC2; DJS; cMRP
Study 30335438 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 30335480 — Predictive Biomarker (PRD): ACVR1B mRNA
Genes: ACVR1B; ACVRLK4; ALK4
Study 30335781 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 30335787 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 30336693 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30336828 — Predictive Biomarker (PRD): TTR mRNA
Genes: TTR; PALB
Study 30337280 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 30337314 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30338661 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 30340199 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 30340199 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 30340199 — Predictive Biomarker (PRD): JAK2 mRNA
Genes: JAK2
Study 30340199 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 30340539 — Predictive Biomarker (PRD): PCSK6 mRNA
Genes: PCSK6; PACE4
Study 30341050 — Surrogate Endpoint (SUR): Blood pressure
Study 30341050 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30341052 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study 30341278 — Predictive Biomarker (PRD): SLC6A2 mRNA
Genes: SLC6A2; NAT1; NET1; SLC6A5
Study 30341278 — Safety Biomarker (SAF): miR-579
Genes: MIR579
Study 30341970 — Surrogate Endpoint (SUR): Serum creatinine
Study 30343614 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30343896 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30343896 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30343896 — Predictive Biomarker (PRD): PTPRZ1 mRNA
Genes: PTPRZ1; HTPZP2; PTPRZ; PTPRZ2; PTPZ
Study 30344063 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30346831 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 30347025 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-X-C motif chemokine 10
Genes: CXCL10; INP10; SCYB10
Study 30347025 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30348127 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-20a
Genes: MIR20A
Study 30348127 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-34a
Genes: MIR34A
Study 30348127 — Predictive Biomarker (PRD): miR-106b
Genes: MIR106B
Study 30348127 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-320b
Study 30348127 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30348127 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 30348127 — Safety Biomarker (SAF): miR-378a-5p
Genes: MIR378A
Study 30348224 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30348537 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 30348538 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 30348618 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30348638 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 30349338 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30350134 — Surrogate Endpoint (SUR): Probing pocket depth
Study 30350179 — Predictive Biomarker (PRD): TPI1 mRNA
Genes: TPI1; TPI
Study 30351341 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30351387 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30352941 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30352941 — Predictive Biomarker (PRD): ALK
Genes: CD246; ALK1
Study 30352941 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30353044 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30353806 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 30354460 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30354721 — Surrogate Endpoint (SUR): Blood pressure
Study 30354737 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30355158 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30355199 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30355760 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30357273 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30358145 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 30358468 — Predictive Biomarker (PRD): MYO7A mRNA
Genes: MYO7A; USH1B
Study 30358468 — Predictive Biomarker (PRD): CDH23 mRNA
Genes: CDH23; KIAA1774; KIAA1812; UNQ1894/PRO4340
Study 30358468 — Predictive Biomarker (PRD): PCDH15 mRNA
Genes: PCDH15; USH1F
Study 30358468 — Predictive Biomarker (PRD): USH1C mRNA
Genes: USH1C; AIE75
Study 30358859 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 30359909 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30361875 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30361875 — Predictive Biomarker (PRD): Hormone receptor
Study 30362288 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30363395 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 30363954 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30363954 — Safety Biomarker (SAF): BDNF
Study 30364428 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30365452 — Predictive Biomarker (PRD): RALA mRNA
Genes: RALA; RAL
Study 30365452 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30366581 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 30367117 — Predictive Biomarker (PRD): TMPRSS2 mRNA
Genes: TMPRSS2; PRSS10
Study 30367117 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 30370468 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30371285 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30371301 — Surrogate Endpoint (SUR): Blood pressure
Study 30371728 — Surrogate Endpoint (SUR): Blood pressure
Study 30373600 — Safety Biomarker (SAF): miR-340-5p
Genes: MIR340
Study 30373600 — Safety Biomarker (SAF): miR-142
Genes: MIR142
Study 30373638 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Angiopoietin-2
Genes: ANGPT2
Study 30373638 — Monitoring Biomarker (MOI): Angiopoietin-1
Genes: ANGPT1; KIAA0003
Study 30373683 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30373683 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30373731 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 30374460 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study 30374686 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30374686 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor receptor 2
Genes: KDR; FLK1; VEGFR2
Study 30374686 — Predictive Biomarker (PRD): PDGFRB mRNA
Genes: PDGFRB; PDGFR; PDGFR1
Study 30374686 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30377991 — Predictive Biomarker (PRD): MMD mRNA
Genes: MMD; PAQR11
Study 30380386 — Predictive Biomarker (PRD): CD47 mRNA
Genes: CD47; MER6
Study 30381078 — Predictive Biomarker (PRD): PDPK1 mRNA
Genes: PDPK1; PDK1
Study 30381078 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 30381078 — Predictive Biomarker (PRD): PTK2 mRNA
Genes: PTK2; FAK; FAK1
Study 30381078 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 30383140 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 30383140 — Predictive Biomarker (PRD): PDGFRA mRNA
Genes: PDGFRA; PDGFR2; RHEPDGFRA
Study 30383781 — Surrogate Endpoint (SUR): Blood pressure
Study 30384846 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 30384846 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30384846 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 30387527 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 30388073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30388073 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30388108 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30389646 — Surrogate Endpoint (SUR): Blood pressure
Study 30390170 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 30390672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30390672 — Safety Biomarker (SAF): IL-6 and IL-10
Study 30390672 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30390672 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30391805 — Predictive Biomarker (PRD): INSR mRNA
Genes: INSR
Study 30391805 — Pharmacodynamic Biomarker (PDY): Insulin receptor substrate 1
Genes: IRS1
Study 30392813 — Predictive Biomarker (PRD): SHH mRNA
Genes: SHH
Study 30392813 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 30392813 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study 30393621 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 30393825 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 30394678 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 30396014 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30396833 — Predictive Biomarker (PRD): SHANK3 mRNA
Genes: SHANK3; KIAA1650; PROSAP2; PSAP2
Study 30397669 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 30397669 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 30397669 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 30398220 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30398516 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30400780 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30400986 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 30400986 — Monitoring Biomarker (MOI): Cell-free DNA
Study 30401669 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 30402678 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30402678 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 30405426 — Surrogate Endpoint (SUR): Blood pressure
Study 30406948 — Predictive Biomarker (PRD): ARCN1 mRNA
Genes: ARCN1; COPD
Study 30408788 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 30411081 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Osteopontin
Genes: SPP1; BNSP; OPN; PSEC0156
Study 30411081 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 30411081 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30411151 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 30412493 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 30413378 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study 30413378 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study 30413829 — Predictive Biomarker (PRD): SLC2A2 mRNA
Genes: SLC2A2; GLUT2
Study 30414054 — Surrogate Endpoint (SUR): Blood pressure
Study 30414064 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30415451 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30416770 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30418117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30418117 — Predictive Biomarker (PRD): PADI2 mRNA
Genes: PADI2; KIAA0994; PAD2; PDI2
Study 30418117 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 30418117 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 30418574 — Predictive Biomarker (PRD): LEP mRNA
Genes: LEP; OB; OBS
Study 30418599 — Surrogate Endpoint (SUR): Forced vital capacity
Study 30420614 — Predictive Biomarker (PRD): FGFR2 mRNA
Genes: FGFR2; BEK; KGFR; KSAM
Study 30420614 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 30421265 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 30421265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30425824 — Predictive Biomarker (PRD): FMN1 mRNA
Genes: FMN1; FMN; LD
Study 30425843 — Predictive Biomarker (PRD): Thymidylate synthase 
Genes: TYMS; TS; OK/SW-cl.29
Study 30427584 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 30427584 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 30427584 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 30429013 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30430326 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 30431292 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 30431292 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30442257 — Surrogate Endpoint (SUR): Blood pressure
Study 30442502 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study 30442503 — Predictive Biomarker (PRD): DEK mRNA
Genes: DEK
Study 30442503 — Predictive Biomarker (PRD): NUP214 mRNA
Genes: NUP214; CAIN; CAN; KIAA0023
Study 30442503 — Predictive Biomarker (PRD): RUNX1 mRNA
Genes: RUNX1; AML1; CBFA2
Study 30442503 — Predictive Biomarker (PRD): RUNX1T1 mRNA
Genes: RUNX1T1; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Study 30442503 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MYH11 mRNA
Genes: MYH11; KIAA0866
Study 30442503 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 30442743 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 30443431 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 30444200 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30444200 — Predictive Biomarker (PRD): CD28 mRNA
Genes: CD28
Study 30444200 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 30444200 — Predictive Biomarker (PRD): ICOS mRNA
Genes: ICOS; AILIM
Study 30444283 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 30444686 — Predictive Biomarker (PRD): MYCN mRNA
Genes: MYCN; BHLHE37; NMYC
Study 30446007 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 30446007 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30446354 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30446499 — Predictive Biomarker (PRD): TUBB1 mRNA
Genes: TUBB1
Study 30446575 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 30446785 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30448343 — Predictive Biomarker (PRD): Microsatellite instability
Study 30449712 — Predictive Biomarker (PRD): CAPS mRNA
Genes: CAPS
Study 30450044 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30450044 — Safety Biomarker (SAF): BDNF
Study 30450553 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 30451764 — Surrogate Endpoint (SUR): Pathological complete response
Study 30457897 — Predictive Biomarker (PRD): Programmed cell death 1 ligand 1
Genes: CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
Study 30459098 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study 30459647 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30459647 — Safety Biomarker (SAF): BDNF
Study 30460495 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 30460774 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 30462244 — Surrogate Endpoint (SUR): Blood pressure
Study 30463526 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 30463526 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 30463996 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 30464579 — Predictive Biomarker (PRD): BPI mRNA
Genes: BPI
Study 30465166 — Predictive Biomarker (PRD): CYP21A2 mRNA
Genes: CYP21A2; CYP21; CYP21B
Study 30465166 — Predictive Biomarker (PRD): C4A mRNA
Genes: C4A; CO4; CPAMD2
Study 30466205 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 30466410 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 30467135 — Surrogate Endpoint (SUR): Blood pressure
Study 30468137 — Pharmacodynamic Biomarker (PDY): Cyclic adenosine monophosphate
Study 30468243 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 30468243 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 30468243 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30468243 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 30468243 — Predictive Biomarker (PRD): CSMD1 mRNA
Genes: CSMD1; KIAA1890; UNQ5952/PRO19863
Study 30471555 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30471555 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 30471555 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30471555 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30471555 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30471555 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 30472259 — Predictive Biomarker (PRD): PALB2 mRNA
Genes: PALB2; FANCN
Study 30472259 — Predictive Biomarker (PRD): RNF8 mRNA
Genes: RNF8; KIAA0646
Study 30472259 — Predictive Biomarker (PRD): LRIF1 mRNA
Genes: LRIF1; C1orf103; RIF1
Study 30472259 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 30472651 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 30473706 — Predictive Biomarker (PRD): GART mRNA
Genes: GART; PGFT; PRGS
Study 30474567 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 30476179 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 30476179 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30476179 — Surrogate Endpoint (SUR): Bone mineral density
Study 30476179 — Safety Biomarker (SAF): BDNF
Study 30476655 — Predictive Biomarker (PRD): THBS1 mRNA
Genes: THBS1; TSP; TSP1
Study 30476723 — Predictive Biomarker (PRD): BRD4 mRNA
Genes: BRD4; HUNK1
Study 30476968 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 30476968 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 30476968 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study 30477436 — Predictive Biomarker (PRD): SERPINA5 mRNA
Genes: SERPINA5; PCI; PLANH3; PROCI
Study 30477518 — Surrogate Endpoint (SUR): Bone mineral density
Study 30477572 — Predictive Biomarker (PRD): HOXA3 mRNA
Genes: HOXA3; HOX1E
Study 30477572 — Predictive Biomarker (PRD): HOXA5 mRNA
Genes: HOXA5; HOX1C
Study 30477572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 30477572 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 30477572 — Predictive Biomarker (PRD): HOXC13 mRNA
Genes: HOXC13; HOX3G
Study 30477895 — Predictive Biomarker (PRD): ADCYAP1 mRNA
Genes: ADCYAP1
Study 30478190 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30478190 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor