TrialPanorama/TrialPanorama-database huggingface dataset:
Study 28045766 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19747021 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30617950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30617950 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28899222 — Surrogate Endpoint (SUR): Blood pressure
Study 24113197 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24113197 — Surrogate Endpoint (SUR): Bone mineral density
Study 24113197 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31751449 — Surrogate Endpoint (SUR): Blood pressure
Study 18191048 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 1 beta
Genes: IL1B; IL1F2
Study 18191048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 18191048 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8237806 — Surrogate Endpoint (SUR): Serum potassium
Study 27127913 — Surrogate Endpoint (SUR): Blood pressure
Study 23253957 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 20389141 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20389141 — Predictive Biomarker (PRD): Hormone receptor
Study 18241756 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 30887581 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15381923 — Predictive Biomarker (PRD): RGS4 mRNA
Genes: RGS4
Study 12160194 — Surrogate Endpoint (SUR): Blood pressure
Study 31165191 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study 18070204 — Monitoring Biomarker (MOI): Matrix metalloproteinase 1
Genes: MMP1; CLG
Study 1735269 — Predictive Biomarker (PRD): PTPRF mRNA
Genes: PTPRF; LAR
Study 30915650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30915650 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30915650 — Surrogate Endpoint (SUR): Blood pressure
Study 18622283 — Surrogate Endpoint (SUR): Serum creatinine
Study 18622283 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18622283 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25069759 — Surrogate Endpoint (SUR): Hematologic response
Study 17934240 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 11932277 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 11932277 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16415894 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16415894 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 14760948 — Predictive Biomarker (PRD): CD80 mRNA
Genes: CD80; CD28LG; CD28LG1; LAB7
Study 14760948 — Pharmacodynamic Biomarker (PDY): T-lymphocyte activation antigen CD86
Genes: CD86; CD28LG2
Study 11369502 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 11369502 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1517383 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 1517383 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1517383 — Surrogate Endpoint (SUR): Serum calcium
Study 31955491 — Predictive Biomarker (PRD): SAT1 mRNA
Genes: SAT1; SAT
Study 31955491 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 31955491 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29794738 — Surrogate Endpoint (SUR): Blood pressure
Study 29188876 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 24100785 — Surrogate Endpoint (SUR): Serum uric acid
Study 28468616 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 21436319 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 26972606 — Surrogate Endpoint (SUR): Blood pressure
Study 11122886 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 23452940 — Surrogate Endpoint (SUR): Blood pressure
Study 27737714 — Surrogate Endpoint (SUR): Blood pressure
Study 10373048 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 8561069 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1652597 — Surrogate Endpoint (SUR): Blood pressure
Study 22922768 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20519806 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 20519806 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 18230824 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26795282 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study 26795282 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 26795282 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 26795282 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26795282 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study 26795282 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20546629 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 14521272 — Predictive Biomarker (PRD): F3 mRNA
Genes: F3
Study 8526786 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 278459 — Surrogate Endpoint (SUR): Serum potassium
Study 278459 — Surrogate Endpoint (SUR): Blood pressure
Study 24068472 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 7433340 — Surrogate Endpoint (SUR): Blood pressure
Study 7433340 — Safety Biomarker (SAF): 51Cr-EDTA
Study 30393950 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 25604346 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 28155333 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19141327 — Surrogate Endpoint (SUR): Urine free cortisol
Study 15162076 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10795118 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 1549937 — Surrogate Endpoint (SUR): Blood pressure
Study 28233454 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 18958548 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 18958548 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 1576099 — Surrogate Endpoint (SUR): Blood pressure
Study 30315670 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 24981311 — Predictive Biomarker (PRD): CXCR4 mRNA
Genes: CXCR4
Study 22177821 — Surrogate Endpoint (SUR): Blood pressure
Study 18398639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18398639 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10784386 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 19863361 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 16759927 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15025600 — Surrogate Endpoint (SUR): Blood pressure
Study 28333318 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 25973439 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 25973439 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 16289977 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16289977 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16289977 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8490070 — Surrogate Endpoint (SUR): Blood pressure
Study 24973959 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 20125186 — Surrogate Endpoint (SUR): Blood pressure
Study 18305548 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18305548 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 18305548 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 10228046 — Predictive Biomarker (PRD): FCGR2B
Genes: CD32; CD32B; FcgammaRIIb; FcGRIIB
Study 2029988 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 28644246 — Predictive Biomarker (PRD): KIR2DS4 mRNA
Genes: KIR2DS4; CD158I; KKA3; NKAT8
Study 24474552 — Surrogate Endpoint (SUR): Blood pressure
Study 7700069 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7700069 — Surrogate Endpoint (SUR): Blood pressure
Study 29706497 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 19615825 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 12604935 — Surrogate Endpoint (SUR): Blood pressure
Study 10817726 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10817726 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 28233481 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25059838 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 23474741 — Surrogate Endpoint (SUR): Probing pocket depth
Study 22943820 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15801937 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 20666269 — Surrogate Endpoint (SUR): Blood pressure
Study 18789680 — Safety Biomarker (SAF): Transforming growth factor beta 1
Genes: TGFB1; TGFB
Study 8608441 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 23861993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 2531901 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 2531901 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 31909554 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 24555998 — Monitoring Biomarker (MOI): HBV DNA
Study 23212717 — Surrogate Endpoint (SUR): Blood pressure
Study 7624397 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 2647605 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 8388403 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 8388403 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 24351876 — Surrogate Endpoint (SUR): Blood pressure
Study 19914369 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16427526 — Surrogate Endpoint (SUR): Blood pressure
Study 17179770 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 15123223 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9678714 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 31477168 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31477168 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 26555352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26555352 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26555352 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16924032 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 15043759 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 31077250 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31077250 — Predictive Biomarker (PRD): DMD mRNA
Genes: DMD
Study 31077250 — Surrogate Endpoint (SUR): Blood pressure
Study 30303905 — Surrogate Endpoint (SUR): Blood pressure
Study 26049866 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 26049866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26049866 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22271481 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19908172 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11896309 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24045634 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24045634 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 16421350 — Surrogate Endpoint (SUR): Blood pressure
Study 16421350 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16421350 — Surrogate Endpoint (SUR): Bone mineral density
Study 2655719 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 20582610 — Surrogate Endpoint (SUR): Probing pocket depth
Study 7776455 — Surrogate Endpoint (SUR): Serum creatinine
Study 2772366 — Predictive Biomarker (PRD): PPL mRNA
Genes: PPL; KIAA0568
Study 2772366 — Predictive Biomarker (PRD): COTL1 mRNA
Genes: COTL1; CLP
Study 2772366 — Surrogate Endpoint (SUR): Blood pressure
Study 22894574 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 9084463 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9084463 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 10856867 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26752109 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study 22305273 — Predictive Biomarker (PRD): MARS1 mRNA
Genes: MARS1; MARS
Study 28606085 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24902962 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8080071 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 22766314 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 17719471 — Surrogate Endpoint (SUR): Blood pressure
Study 17719471 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17719471 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11427774 — Surrogate Endpoint (SUR): Blood pressure
Study 9250598 — Safety Biomarker (SAF): Eosinophil cationic protein
Genes: RNASE3; ECP; RNS3
Study 31554075 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 31554075 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31554075 — Predictive Biomarker (PRD): AGER mRNA
Genes: AGER; RAGE
Study 31554075 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 26169304 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24983187 — Surrogate Endpoint (SUR): Blood pressure
Study 26479024 — Predictive Biomarker (PRD): IK mRNA
Genes: IK; RED; RER
Study 20796154 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9856895 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 2171853 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30422243 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 3188824 — Surrogate Endpoint (SUR): Blood pressure
Study 29570598 — Surrogate Endpoint (SUR): Blood pressure
Study 23611893 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 11084060 — Predictive Biomarker (PRD): SRL mRNA
Genes: SRL
Study 11084060 — Surrogate Endpoint (SUR): Serum creatinine
Study 2938872 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 2938872 — Surrogate Endpoint (SUR): Blood pressure
Study 12443833 — Surrogate Endpoint (SUR): Blood pressure
Study 8562470 — Surrogate Endpoint (SUR): Blood pressure
Study 2292349 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31039280 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Growth/differentiation factor 15
Genes: GDF15; MIC1; PDF; PLAB; PTGFB
Study 3605188 — Surrogate Endpoint (SUR): Serum triglycerides
Study 30856112 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 26667262 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 26667262 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23361101 — Surrogate Endpoint (SUR): Blood pressure
Study 10742724 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 26988767 — Surrogate Endpoint (SUR): Blood pressure
Study 9039154 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 23781269 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 23781269 — Surrogate Endpoint (SUR): Blood pressure
Study 17716735 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 17378372 — Surrogate Endpoint (SUR): Blood pressure
Study 26797266 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 26797266 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24796977 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 19040000 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 19040000 — Surrogate Endpoint (SUR): Bone mineral density
Study 8629887 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 27169837 — Surrogate Endpoint (SUR): Blood pressure
Study 10438259 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10438259 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7586435 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 2147914 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 2147914 — Surrogate Endpoint (SUR): Blood pressure
Study 26520398 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 15785163 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15259398 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 15259398 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 26197999 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 10323778 — Surrogate Endpoint (SUR): Serum triglycerides
Study 21432821 — Predictive Biomarker (PRD): GLS mRNA
Genes: GLS; GLS1; KIAA0838
Study 27568303 — Predictive Biomarker (PRD): LTB4R mRNA
Genes: LTB4R; BLT; BLT1; BLTR; CMKRL1; GPR16; P2RY7
Study 23717118 — Safety Biomarker (SAF): ACE
Genes: ACE1; CD143
Study 7885287 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31026303 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28582393 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21625183 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19927726 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 12658483 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1431344 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24603216 — Surrogate Endpoint (SUR): Blood pressure
Study 22045925 — Surrogate Endpoint (SUR): Blood pressure
Study 8728171 — Surrogate Endpoint (SUR): Blood pressure
Study 1824736 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 31345387 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 24072232 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 18312768 — Surrogate Endpoint (SUR): Blood pressure
Study 16842145 — Safety Biomarker (SAF): Reactive oxygen species
Study 30524633 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 28324268 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 16299259 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 16299259 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 15270890 — Surrogate Endpoint (SUR): Serum calcium
Study 9359979 — Predictive Biomarker (PRD): DST mRNA
Genes: DST; BP230; BP240; BPAG1; DMH; DT; KIAA0728
Study 31106659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31106659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31106659 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20374035 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 20374035 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 29143803 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 23336160 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23336160 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29858218 — Predictive Biomarker (PRD): REG3A mRNA
Genes: REG3A; HIP; PAP; PAP1
Study 29858218 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 27908500 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21803405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Placenta growth factor
Genes: PGF; PGFL; PLGF
Study 25677598 — Surrogate Endpoint (SUR): Blood pressure
Study 25143296 — Predictive Biomarker (PRD): SLC22A1 mRNA
Genes: SLC22A1; OCT1
Study 25143296 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 25143296 — Predictive Biomarker (PRD): SLC22A3 mRNA
Genes: SLC22A3; EMTH; OCT3
Study 21993383 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19282202 — Surrogate Endpoint (SUR): Blood pressure
Study 18251162 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12201623 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein