TrialPanorama/TrialPanorama-database huggingface dataset:
Study 26811103 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24812309 — Predictive Biomarker (PRD): ENG mRNA
Genes: ENG; END
Study 22102701 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28659293 — Surrogate Endpoint (SUR): Blood pressure
Study 21835957 — Predictive Biomarker (PRD): NOTCH1 mRNA
Genes: NOTCH1; TAN1
Study 21835957 — Predictive Biomarker (PRD): BAALC mRNA
Genes: BAALC
Study 18535785 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20961967 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 20961967 — Predictive Biomarker (PRD): PPARG mRNA
Genes: PPARG; NR1C3
Study 20961967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 20961967 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 201937 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 201937 — Predictive Biomarker (PRD): CXADR mRNA
Genes: CXADR; CAR
Study 19278581 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study 19278581 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 19278581 — Safety Biomarker (SAF): Human leucocyte antigen
Study 7894897 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 2974630 — Predictive Biomarker (PRD): SCT mRNA
Genes: SCT
Study 26805495 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19735378 — Surrogate Endpoint (SUR): Bone mineral density
Study 17023156 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 11004846 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 16644710 — Predictive Biomarker (PRD): PLTP mRNA
Genes: PLTP
Study 16644710 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 14728760 — Predictive Biomarker (PRD): GARS1 mRNA
Genes: GARS1; GARS
Study 8905205 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 1915427 — Surrogate Endpoint (SUR): Blood pressure
Study 9130735 — Surrogate Endpoint (SUR): Bone mineral density
Study 3315118 — Predictive Biomarker (PRD): C1QL1 mRNA
Genes: C1QL1; C1QRF; CRF; CTRP14
Study 21691804 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 16113850 — Surrogate Endpoint (SUR): Blood pressure
Study 28744993 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28744993 — Predictive Biomarker (PRD): Hypoxia-inducible factor 1-alpha
Genes: HIF1A; BHLHE78; MOP1; PASD8
Study 24050419 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21474700 — Surrogate Endpoint (SUR): Blood pressure
Study 20037644 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 20037644 — Predictive Biomarker (PRD): FOXP3 mRNA
Genes: FOXP3; IPEX; JM2
Study 16773437 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study 16773437 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16773437 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study 11085807 — Surrogate Endpoint (SUR): Serum calcium
Study 11085807 — Surrogate Endpoint (SUR): Bone mineral density
Study 23502660 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 23502660 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 17084250 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 17084250 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 17084250 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26329674 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16353199 — Predictive Biomarker (PRD): BAK1 mRNA
Genes: BAK1; BAK; BCL2L7; CDN1
Study 16353199 — Predictive Biomarker (PRD); Safety Biomarker (SAF): MUC5AC mRNA
Genes: MUC5AC; MUC5
Study 424688 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 30155678 — Predictive Biomarker (PRD): Zinc finger protein GLI1
Genes: GLI1; GLI
Study 30155678 — Predictive Biomarker (PRD): Mothers against decapentaplegic homolog 2
Genes: SMAD2; MADH2; MADR2
Study 30155678 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 30155678 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 16343082 — Safety Biomarker (SAF): Hydroxyphenylpyruvate dioxygenase
Genes: HPD; PPD
Study 11991445 — Surrogate Endpoint (SUR): Bone mineral density
Study 21236502 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17112807 — Predictive Biomarker (PRD): ABCC2 mRNA
Genes: ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Study 9010146 — Predictive Biomarker (PRD): THPO mRNA
Genes: THPO; MGDF
Study 29909708 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 27142805 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 25002391 — Surrogate Endpoint (SUR): Blood pressure
Study 18721084 — Surrogate Endpoint (SUR): Blood pressure
Study 18721084 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18721084 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22461416 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 9647551 — Predictive Biomarker (PRD): CPA1 mRNA
Genes: CPA1; CPA
Study 7983648 — Predictive Biomarker (PRD): SLAMF1 mRNA
Genes: SLAMF1; SLAM
Study 2596428 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 2596428 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 4080 — Surrogate Endpoint (SUR): Blood pressure
Study 26493435 — Predictive Biomarker (PRD): MOXD1 mRNA
Genes: MOXD1; MOX; UNQ2493/PRO5780
Study 16984588 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 16874155 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 7854524 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30641618 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 30641618 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 30641618 — Predictive Biomarker (PRD): MFSD11 mRNA
Genes: MFSD11; ET
Study 30641618 — Surrogate Endpoint (SUR): Blood pressure
Study 20438782 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 12969101 — Predictive Biomarker (PRD): EDA mRNA
Genes: EDA; ED1; EDA2
Study 12969101 — Surrogate Endpoint (SUR): Forced vital capacity
Study 10939786 — Surrogate Endpoint (SUR): Blood pressure
Study 10939786 — Predictive Biomarker (PRD): Apolipoprotein E
Genes: APOE
Study 8967704 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1548923 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 3933102 — Predictive Biomarker (PRD): ABR mRNA
Genes: ABR
Study 28829923 — Surrogate Endpoint (SUR): Blood pressure
Study 25215530 — Surrogate Endpoint (SUR): Blood pressure
Study 25215530 — Surrogate Endpoint (SUR): Serum triglycerides
Study 18364139 — Predictive Biomarker (PRD): TFG mRNA
Genes: TFG
Study 18364139 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 8766067 — Surrogate Endpoint (SUR): Blood pressure
Study 22807523 — Predictive Biomarker (PRD): IFNL3 mRNA
Genes: IFNL3; IL28B; IL28C; ZCYTO22
Study 21162963 — Surrogate Endpoint (SUR): Blood pressure
Study 25313574 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study 19967420 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 19967420 — Safety Biomarker (SAF): Cytochrome c
Study 12219187 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 24856796 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24856796 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 22253903 — Safety Biomarker (SAF): Interleukin 1
Study 22499288 — Surrogate Endpoint (SUR): Blood pressure
Study 22499288 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18525300 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 31152309 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 23988855 — Surrogate Endpoint (SUR): Serum creatinine
Study 8282361 — Surrogate Endpoint (SUR): Blood pressure
Study 18682739 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 6125636 — Surrogate Endpoint (SUR): Blood pressure
Study 6125636 — Surrogate Endpoint (SUR): Serum potassium
Study 24120714 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22688509 — Monitoring Biomarker (MOI): HBV DNA
Study 2595265 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30662324 — Monitoring Biomarker (MOI): HBV DNA
Study 30662324 — Surrogate Endpoint (SUR): Serum creatinine
Study 12756868 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 24322377 — Predictive Biomarker (PRD): GEM mRNA
Genes: GEM; KIR
Study 16171631 — Predictive Biomarker (PRD): OAT mRNA
Genes: OAT
Study 10212074 — Surrogate Endpoint (SUR): Bone mineral density
Study 7995773 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 15455188 — Surrogate Endpoint (SUR): Bone mineral density
Study 31872245 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 31872245 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22947291 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22947291 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 20922865 — Surrogate Endpoint (SUR): Blood pressure
Study 12619939 — Surrogate Endpoint (SUR): Bone mineral density
Study 10574619 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 29439289 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 24011069 — Predictive Biomarker (PRD): FGF21 mRNA
Genes: FGF21; UNQ3115/PRO10196
Study 24011069 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 24011069 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26844723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26844723 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15702438 — Pharmacodynamic Biomarker (PDY): High-frequency oscillations
Study 26283236 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9507989 — Surrogate Endpoint (SUR): Blood pressure
Study 360366 — Surrogate Endpoint (SUR): Blood pressure
Study 30257549 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 30257549 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30257549 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26406234 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26406234 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22704398 — Predictive Biomarker (PRD): PNPLA3 mRNA
Genes: PNPLA3; ADPN; C22orf20
Study 18356603 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18356603 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 25339110 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 19542011 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19542011 — Surrogate Endpoint (SUR): Blood pressure
Study 19542011 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31135812 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16287956 — Surrogate Endpoint (SUR): Blood pressure
Study 16287956 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16287956 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 7485045 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7485045 — Surrogate Endpoint (SUR): Blood pressure
Study 7011597 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 7011597 — Surrogate Endpoint (SUR): Blood pressure
Study 23260332 — Predictive Biomarker (PRD): MCIDAS mRNA
Genes: MCIDAS; IDAS; MCI; MCIN
Study 11402637 — Surrogate Endpoint (SUR): Serum testosterone
Study 26350752 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 26350752 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study 26350752 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 31126577 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 29025631 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24335920 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 24335920 — Safety Biomarker (SAF): Epiregulin
Genes: EREG
Study 11309004 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 11309004 — Surrogate Endpoint (SUR): Serum sodium
Study 11309004 — Surrogate Endpoint (SUR): Serum potassium
Study 9128209 — Surrogate Endpoint (SUR): Blood pressure
Study 25480348 — Surrogate Endpoint (SUR): Bone mineral density
Study 22546009 — Safety Biomarker (SAF): Glucose-6-phosphate dehydrogenase
Genes: G6PD
Study 9272773 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 3083793 — Surrogate Endpoint (SUR): Blood pressure
Study 29626232 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 29626232 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 29626232 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 19236691 — Surrogate Endpoint (SUR): Blood pressure
Study 16585412 — Surrogate Endpoint (SUR): Blood pressure
Study 15147122 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 23404297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23404297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23404297 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 1328567 — Surrogate Endpoint (SUR): Blood pressure
Study 11589267 — Surrogate Endpoint (SUR): Serum triglycerides
Study 11589267 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 9846035 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23702942 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23702942 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28960312 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 28960312 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8068446 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 10668716 — Surrogate Endpoint (SUR): Forced vital capacity
Study 17426211 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 9923411 — Predictive Biomarker (PRD): IL11
Genes: IL-11; AGIF
Study 9243145 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 25593053 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study 16750467 — Surrogate Endpoint (SUR): Blood pressure
Study 11207085 — Surrogate Endpoint (SUR): Blood pressure
Study 8422853 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29858113 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29858113 — Surrogate Endpoint (SUR): Bone mineral density
Study 10198825 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study 21120562 — Predictive Biomarker (PRD): TH mRNA
Genes: TH; TYH
Study 10048504 — Surrogate Endpoint (SUR): Blood pressure
Study 10048504 — Surrogate Endpoint (SUR): Serum creatinine
Study 30711003 — Predictive Biomarker (PRD): ID1 mRNA
Genes: ID1; BHLHB24; ID
Study 20058592 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 3356049 — Surrogate Endpoint (SUR): Blood pressure
Study 29434529 — Surrogate Endpoint (SUR): Bone mineral density
Study 28299944 — Surrogate Endpoint (SUR): Blood pressure
Study 28299944 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28299944 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 26625880 — Surrogate Endpoint (SUR): Serum uric acid
Study 26625880 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14637261 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 31629573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 26089210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26089210 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20832994 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20832994 — Surrogate Endpoint (SUR): Blood pressure
Study 658107 — Surrogate Endpoint (SUR): Blood pressure
Study 25218898 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9846303 — Surrogate Endpoint (SUR): Blood pressure
Study 7866597 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7866597 — Surrogate Endpoint (SUR): Blood pressure
Study 24015701 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 24015701 — Surrogate Endpoint (SUR): Serum testosterone
Study 16708043 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 14711550 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 11290880 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 19502254 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11221825 — Predictive Biomarker (PRD): APC mRNA
Genes: APC; DP2.5
Study 22551119 — Safety Biomarker (SAF): Reactive oxygen species
Study 20705564 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 1693738 — Surrogate Endpoint (SUR): Blood pressure
Study 18824040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9040547 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 31597622 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7477984 — Pharmacodynamic Biomarker (PDY): Huntingtin
Genes: HTT; HD; IT15
Study 26687697 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Platelet glycoprotein 4
Genes: CD36; GP3B; GP4
Study 23311957 — Surrogate Endpoint (SUR): Blood pressure
Study 18300861 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 18300861 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 7968336 — Surrogate Endpoint (SUR): Blood pressure
Study 12866362 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30477911 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19534021 — Surrogate Endpoint (SUR): Blood pressure
Study 17519271 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2745339 — Surrogate Endpoint (SUR): Forced vital capacity
Study 31904863 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 31904863 — Predictive Biomarker (PRD): DCN mRNA
Genes: DCN; SLRR1B
Study 31904863 — Predictive Biomarker (PRD): PLAU mRNA
Genes: PLAU
Study 31904863 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 24252717 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 11238511 — Surrogate Endpoint (SUR): Bone mineral density
Study 11238511 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 15197018 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15197018 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 15197018 — Surrogate Endpoint (SUR): Blood pressure
Study 16760903 — Safety Biomarker (SAF): Reactive oxygen species
Study 2888942 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12002664 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 27465608 — Surrogate Endpoint (SUR): Blood pressure
Study 27465608 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 9872843 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30759887 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 30759887 — Monitoring Biomarker (MOI): Alpha-1-acid glycoprotein 1
Genes: ORM1; AGP1
Study 24632316 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 26371134 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 23681913 — Surrogate Endpoint (SUR): Blood pressure
Study 19451435 — Predictive Biomarker (PRD): KIT mRNA
Genes: KIT; SCFR
Study 9612276 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 31112026 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 28866763 — Surrogate Endpoint (SUR): Bone mineral density
Study 7603076 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 7603076 — Surrogate Endpoint (SUR): Blood pressure
Study 23909402 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20708714 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 17408055 — Surrogate Endpoint (SUR): Blood pressure
Study 16280697 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2