TrialPanorama/TrialPanorama-database huggingface dataset:
Study 31345107 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31345107 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 28430522 — Surrogate Endpoint (SUR): Blood pressure
Study 25746727 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 1646259 — Surrogate Endpoint (SUR): Blood pressure
Study 28881147 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 28881147 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 28881147 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 24576517 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22510506 — Predictive Biomarker (PRD): SDS mRNA
Genes: SDS; SDH
Study 22510506 — Predictive Biomarker (PRD): TSPAN31 mRNA
Genes: TSPAN31; SAS
Study 10575655 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 10575655 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 30514777 — Predictive Biomarker (PRD): O-6-methylguanine-DNA-alkyltransferase
Genes: MGMT
Study 29110641 — Surrogate Endpoint (SUR): Blood pressure
Study 26205609 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 23917472 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22001911 — Predictive Biomarker (PRD): KDM5D mRNA
Genes: KDM5D; HY; HYA; JARID1D; KIAA0234; SMCY
Study 19161480 — Predictive Biomarker (PRD): LRIT1 mRNA
Genes: LRIT1; LRRC21; PAL
Study 17541944 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11920413 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2254718 — Surrogate Endpoint (SUR): Blood pressure
Study 15450782 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 15450782 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 15450782 — Predictive Biomarker (PRD): GAD2 mRNA
Genes: GAD2; GAD65
Study 11229823 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11229823 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 9893913 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9893913 — Surrogate Endpoint (SUR): Blood pressure
Study 25983669 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19687350 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19687350 — Surrogate Endpoint (SUR): Blood pressure
Study 11069800 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11069800 — Predictive Biomarker (PRD): Interleukin 5
Genes: IL5
Study 9263752 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 9263752 — Surrogate Endpoint (SUR): Blood pressure
Study 28361113 — Predictive Biomarker (PRD): CYP3A5 mRNA
Genes: CYP3A5
Study 9232359 — Surrogate Endpoint (SUR): Blood pressure
Study 2866932 — Surrogate Endpoint (SUR): Blood pressure
Study 2866932 — Surrogate Endpoint (SUR): Serum potassium
Study 22539545 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22539545 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 20146685 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 17118822 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 20106646 — Predictive Biomarker (PRD): PCSK7 mRNA
Genes: PCSK7; LPC; PC7; PC8; SPC7
Study 16086935 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8786163 — Surrogate Endpoint (SUR): Blood pressure
Study 31036091 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 23663336 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 6682323 — Surrogate Endpoint (SUR): Blood pressure
Study 30872010 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 24923300 — Surrogate Endpoint (SUR): Blood pressure
Study 15703368 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 15703368 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 8942490 — Surrogate Endpoint (SUR): Bone mineral density
Study 23583763 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10807457 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 8813924 — Pharmacodynamic Biomarker (PDY): Cyclic guanosine monophosphate
Study 1311660 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1311660 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31325313 — Monitoring Biomarker (MOI): Procalcitonin
Study 25775393 — Predictive Biomarker (PRD): M-phase inducer phosphatase 2
Genes: CDC25B; CDC25HU2
Study 7573259 — Surrogate Endpoint (SUR): Blood pressure
Study 28953989 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 24438360 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 19204201 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 19204201 — Predictive Biomarker (PRD): Hormone receptor
Study 11551104 — Predictive Biomarker (PRD): GJB2 mRNA
Genes: GJB2
Study 10303909 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 16625231 — Surrogate Endpoint (SUR): Serum testosterone
Study 11769817 — Surrogate Endpoint (SUR): Blood pressure
Study 22898215 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18175744 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12646232 — Predictive Biomarker (PRD): MTTP mRNA
Genes: MTTP; MTP
Study 23307206 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study 16773453 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 10228111 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 10228111 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 7671879 — Predictive Biomarker (PRD): TEF mRNA
Genes: TEF; KIAA1655
Study 22813609 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 19227864 — Surrogate Endpoint (SUR): Bone mineral density
Study 1760833 — Surrogate Endpoint (SUR): Blood pressure
Study 31359271 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 31359271 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 24984211 — Surrogate Endpoint (SUR): Bone mineral density
Study 2338688 — Surrogate Endpoint (SUR): Blood pressure
Study 31057081 — Surrogate Endpoint (SUR): Blood pressure
Study 1413984 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 1413984 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 1413984 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29689122 — Monitoring Biomarker (MOI): HBV DNA
Study 28612179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28612179 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25527766 — Predictive Biomarker (PRD): CYP2R1 mRNA
Genes: CYP2R1
Study 25527766 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study 15653658 — Surrogate Endpoint (SUR): Serum creatinine
Study 12204968 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 12204968 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 12204968 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 9097333 — Surrogate Endpoint (SUR): Blood pressure
Study 18356266 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 3542091 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 22092206 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 11703991 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 16670166 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 1433880 — Surrogate Endpoint (SUR): Blood pressure
Study 24576857 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24576857 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 23114133 — Predictive Biomarker (PRD): TNFSF13B mRNA
Genes: TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; UNQ401/PRO738
Study 23114133 — Predictive Biomarker (PRD): TNFSF13 mRNA
Genes: TNFSF13; APRIL; TALL2; ZTNF2; UNQ383/PRO715
Study 23114133 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 23114133 — Predictive Biomarker (PRD): CD27 mRNA
Genes: CD27; TNFRSF7
Study 12625847 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study 9592304 — Predictive Biomarker (PRD): CBS mRNA
Genes: CBS
Study 30452284 — Predictive Biomarker (PRD): REST mRNA
Genes: REST; NRSF; XBR
Study 24919974 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19926841 — Surrogate Endpoint (SUR): Blood pressure
Study 24119736 — Monitoring Biomarker (MOI): HBV DNA
Study 11257243 — Predictive Biomarker (PRD): ELK3 mRNA
Genes: ELK3; NET; SAP2
Study 2894994 — Surrogate Endpoint (SUR): Blood pressure
Study 28282381 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23735408 — Surrogate Endpoint (SUR): Blood pressure
Study 22099892 — Predictive Biomarker (PRD): FN1 mRNA
Genes: FN1; FN
Study 18584303 — Surrogate Endpoint (SUR): Blood pressure
Study 28479901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28479901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28479901 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 28479901 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25131356 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21199787 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18793926 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 3075601 — Surrogate Endpoint (SUR): Blood pressure
Study 31419349 — Predictive Biomarker (PRD): MC1R mRNA
Genes: MC1R; MSHR
Study 31419349 — Predictive Biomarker (PRD): IRF4 mRNA
Genes: IRF4; MUM1
Study 17416370 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8223847 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8223847 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8223847 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31599919 — Surrogate Endpoint (SUR): Blood pressure
Study 18204338 — Surrogate Endpoint (SUR): Blood pressure
Study 16313986 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 30074294 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study 30074294 — Surrogate Endpoint (SUR): Forced vital capacity
Study 22266414 — Predictive Biomarker (PRD): ASL mRNA
Genes: ASL
Study 19460254 — Predictive Biomarker (PRD): PTBP2 mRNA
Genes: PTBP2; NPTB; PTB; PTBLP
Study 16678649 — Predictive Biomarker (PRD): MAS1 mRNA
Genes: MAS1; MAS
Study 8617188 — Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): TNF related activation protein
Genes: CD40LG; CD40L; TNFSF5; TRAP
Study 3001562 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 30909923 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 27391972 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22002277 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 12568409 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 12568409 — Surrogate Endpoint (SUR): Bone mineral density
Study 10860412 — Predictive Biomarker (PRD): MVP mRNA
Genes: MVP; LRP
Study 9327716 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9327716 — Surrogate Endpoint (SUR): Blood pressure
Study 24397981 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 24397981 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 24397981 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 24397981 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 24397981 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7637222 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31787454 — Surrogate Endpoint (SUR): Blood pressure
Study 18467322 — Predictive Biomarker (PRD): LTA mRNA
Genes: LTA; TNFB; TNFSF1
Study 18467322 — Predictive Biomarker (PRD): MEA1 mRNA
Genes: MEA1; MEA
Study 21051930 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 19944362 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19944362 — Surrogate Endpoint (SUR): Blood pressure
Study 7998047 — Surrogate Endpoint (SUR): Blood pressure
Study 8648924 — Surrogate Endpoint (SUR): Serum calcium
Study 24576799 — Surrogate Endpoint (SUR): Blood pressure
Study 11222470 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11222470 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31200823 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 23644079 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 8759064 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1349031 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 25424047 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 7574020 — Surrogate Endpoint (SUR): Blood pressure
Study 27569864 — Surrogate Endpoint (SUR): Blood pressure
Study 15902303 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 9497185 — Surrogate Endpoint (SUR): Blood pressure
Study 6356898 — Surrogate Endpoint (SUR): Blood pressure
Study 30205379 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30205379 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 30205379 — Safety Biomarker (SAF): IL-6 and IL-10
Study 25823668 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 25823668 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23298410 — Predictive Biomarker (PRD): MMRN1 mRNA
Genes: MMRN1; ECM; EMILIN4; GPIA*; MMRN
Study 18694831 — Predictive Biomarker (PRD): CYP2C9 mRNA
Genes: CYP2C9; CYP2C10
Study 16880097 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30992306 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study 30992306 — Predictive Biomarker (PRD): SLC22A3 mRNA
Genes: SLC22A3; EMTH; OCT3
Study 30992306 — Predictive Biomarker (PRD): SLC22A4
Genes: OCTN1; MGC34546
Study 30992306 — Predictive Biomarker (PRD): SLC22A5 mRNA
Genes: SLC22A5; OCTN2
Study 29577681 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study 29577681 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 24475284 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24475284 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22776778 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 16023249 — Predictive Biomarker (PRD): FDPS mRNA
Genes: FDPS; FPS; KIAA1293
Study 28500815 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24064689 — Surrogate Endpoint (SUR): Bone mineral density
Study 2446060 — Surrogate Endpoint (SUR): Blood pressure
Study 27110370 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 27110370 — Surrogate Endpoint (SUR): Serum creatinine
Study 27110370 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 27110370 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18691996 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 18691996 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18691996 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 12464950 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 28369340 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 22882805 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 16513877 — Predictive Biomarker (PRD): DRD2 mRNA
Genes: DRD2
Study 20143119 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20143119 — Surrogate Endpoint (SUR): Blood pressure
Study 20143119 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29421002 — Predictive Biomarker (PRD): KLHL17 mRNA
Genes: KLHL17; AF
Study 27480131 — Predictive Biomarker (PRD): FAP mRNA
Genes: FAP
Study 27480131 — Predictive Biomarker (PRD): SLC25A21 mRNA
Genes: SLC25A21; ODC
Study 21935581 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study 17198904 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 17198904 — Surrogate Endpoint (SUR): Blood pressure
Study 12603176 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 3516764 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 25335675 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16643445 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 10831180 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 8772604 — Surrogate Endpoint (SUR): Bone mineral density
Study 31592623 — Pharmacodynamic Biomarker (PDY): Extracellular signal-regulated kinase
Study 25788018 — Surrogate Endpoint (SUR): Blood pressure
Study 16766544 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 3573541 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 21546927 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 7746030 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 26857383 — Surrogate Endpoint (SUR): Blood pressure
Study 24444280 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 8841152 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 30412448 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 30412448 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 27655761 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 23765873 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20736125 — Surrogate Endpoint (SUR): Blood pressure
Study 11783207 — Predictive Biomarker (PRD): CHM mRNA
Genes: CHM; REP1; TCD
Study 11783207 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8606329 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 25734218 — Surrogate Endpoint (SUR): Blood pressure
Study 25734218 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27318866 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22181006 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 17405792 — Predictive Biomarker (PRD): CYCS mRNA
Genes: CYCS; CYC
Study 31704504 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30609761 — Predictive Biomarker (PRD): MAVS mRNA
Genes: MAVS; IPS1; KIAA1271; VISA
Study 17055120 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 19864308 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 19074684 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 18414360 — Surrogate Endpoint (SUR): Blood pressure
Study 19641050 — Surrogate Endpoint (SUR): Blood pressure
Study 10360048 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 16895881 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 16895881 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 15051213 — Predictive Biomarker (PRD): EED mRNA
Genes: EED
Study 8814427 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 1383618 — Surrogate Endpoint (SUR): Blood pressure
Study 20003224 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 20003224 — Surrogate Endpoint (SUR): Blood pressure
Study 20961348 — Predictive Biomarker (PRD): SFPQ mRNA
Genes: SFPQ; PSF
Study 20961348 — Predictive Biomarker (PRD): DCD mRNA
Genes: DCD; AIDD; DSEP
Study 16305291 — Predictive Biomarker (PRD): CYP3A4 mRNA
Genes: CYP3A4; CYP3A3
Study 26946726 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16234607 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 16234607 — Surrogate Endpoint (SUR): Serum creatinine
Study 16234607 — Surrogate Endpoint (SUR): Blood pressure
Study 17728357 — Predictive Biomarker (PRD): EPX mRNA
Genes: EPX; EPER; EPO; EPP
Study 11589674 — Predictive Biomarker (PRD): SHBG mRNA
Genes: SHBG
Study 11589674 — Surrogate Endpoint (SUR): Bone mineral density
Study 9400916 — Surrogate Endpoint (SUR): Blood pressure
Study 7950410 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Intercellular adhesion molecule 1
Genes: ICAM1
Study 22594907 — Surrogate Endpoint (SUR): Blood pressure