TrialPanorama/TrialPanorama-database huggingface dataset:
Study NCT00059020 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03547453 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00556322 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT00556322 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT01915186 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT01383694 — Predictive Biomarker (PRD): TRPV1 mRNA
Genes: TRPV1; VR1
Study NCT00664014 — Surrogate Endpoint (SUR): Serum sodium
Study NCT02203903 — Predictive Biomarker (PRD): EFS mRNA
Genes: EFS; CASS3
Study NCT05385640 — Surrogate Endpoint (SUR): Serum potassium
Study NCT01959672 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study NCT05401734 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT05401734 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03789565 — Safety Biomarker (SAF): IL-6 and IL-10
Study NCT04342650 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT03582800 — Predictive Biomarker (PRD): STS mRNA
Genes: STS; ARSC1
Study NCT03463850 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT04512807 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00380172 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT02812121 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT02186821 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT02186821 — Predictive Biomarker (PRD): ROS1 mRNA
Genes: ROS1; MCF3; ROS
Study NCT02787876 — Surrogate Endpoint (SUR): Duration of severe neutropenia
Study NCT03853616 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01828099 — Predictive Biomarker (PRD): ALK tyrosine kinase receptor
Genes: ALK
Study NCT03193892 — Predictive Biomarker (PRD): TSC2
Genes: tuberin; LAM; PPP1R160
Study NCT01320254 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT04322292 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT02278835 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT02278835 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT00129675 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study NCT01851135 — Predictive Biomarker (PRD): NF1 mRNA
Genes: NF1
Study NCT00880802 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study NCT01566721 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT02545283 — Predictive Biomarker (PRD): MDM2 mRNA
Genes: MDM2
Study NCT02545283 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Cellular tumor antigen p53
Genes: TP53; P53
Study NCT00996684 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT03600805 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02788682 — Predictive Biomarker (PRD): Vitamin D-binding protein
Genes: GC
Study NCT01499186 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02917525 — Predictive Biomarker (PRD): MGP mRNA
Genes: MGP; MGLAP; GIG36
Study NCT03777826 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT01730638 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study NCT02561845 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study NCT02561845 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT02561845 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study NCT00953030 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01416753 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT01416753 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study NCT01247701 — Predictive Biomarker (PRD): CD52 mRNA
Genes: CD52; CDW52; HE5
Study NCT03238183 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04407403 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05394935 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03832725 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT01961947 — Surrogate Endpoint (SUR): Neutralizing antibody
Study NCT04838093 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT04270461 — Predictive Biomarker (PRD): KLRK1 mRNA
Genes: KLRK1; D12S2489E; NKG2D
Study NCT00101647 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT00101647 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT02154672 — Predictive Biomarker (PRD): BRCA2 mRNA
Genes: BRCA2; FACD; FANCD1
Study NCT04297891 — Predictive Biomarker (PRD): ZFYVE9 mRNA
Genes: ZFYVE9; MADHIP; SARA; SMADIP
Study NCT03496363 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study NCT01036009 — Predictive Biomarker (PRD): CD14 mRNA
Genes: CD14
Study NCT01036009 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01036009 — Predictive Biomarker (PRD): Myeloid cell surface antigen CD33
Genes: CD33; SIGLEC3
Study NCT01036009 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT03532672 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study NCT02472561 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03827356 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study NCT01505413 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01505413 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT04196764 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT06448962 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03940833 — Predictive Biomarker (PRD): TNFRSF17 mRNA
Genes: TNFRSF17; BCM; BCMA
Study NCT03429101 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01838538 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT01838538 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02215850 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study NCT02407509 — Predictive Biomarker (PRD): RAF1 mRNA
Genes: RAF1; RAF
Study NCT02407509 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT02407509 — Predictive Biomarker (PRD): NRAS mRNA
Genes: NRAS; HRAS1
Study NCT01155245 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03580785 — Predictive Biomarker (PRD): PTH1R mRNA
Genes: PTH1R; PTHR; PTHR1
Study NCT02108951 — Predictive Biomarker (PRD): BCR mRNA
Genes: BCR; BCR1; D22S11
Study NCT02108951 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase ABL1
Genes: ABL1; ABL; JTK7
Study NCT04576871 — Predictive Biomarker (PRD): Glutamate carboxypeptidase II
Genes: FOLH1; FOLH; NAALAD1; PSM; PSMA; GIG27
Study NCT02161783 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT03264352 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02296489 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT01660789 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01724294 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study NCT03127644 — Surrogate Endpoint (SUR): Serum potassium
Study NCT05495516 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT05495516 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT04374721 — Predictive Biomarker (PRD): BMAL1 mRNA
Genes: BMAL1; ARNTL; BHLHE5; MOP3; PASD3
Study NCT00295477 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT02476994 — Predictive Biomarker (PRD): FADS1 mRNA
Genes: FADS1; FADSD5
Study NCT01058460 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study NCT03040648 — Predictive Biomarker (PRD): TFEB mRNA
Genes: TFEB; BHLHE35
Study NCT05263102 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT01241669 — Predictive Biomarker (PRD): SLC22A2 mRNA
Genes: SLC22A2; OCT2
Study NCT00850018 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02317718 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study NCT00254449 — Predictive Biomarker (PRD): PGP mRNA
Genes: PGP
Study NCT02702882 — Surrogate Endpoint (SUR): Serum testosterone
Study NCT03776058 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study NCT03477942 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22
Study NCT01053156 — Pharmacodynamic Biomarker (PDY): Matrix metalloproteinase 9
Genes: MMP9; CLG4B
Study NCT03339063 — Predictive Biomarker (PRD): NTM mRNA
Genes: NTM; IGLON2; NT; UNQ297/PRO337
Study NCT04313751 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03730168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT03730168 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00462345 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01614301 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study NCT03984708 — Predictive Biomarker (PRD): IGFALS mRNA
Genes: IGFALS; ALS
Study NCT04262154 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study NCT01802320 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT01802320 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT01350908 — Monitoring Biomarker (MOI): Circulating tumor DNA
Study NCT00164463 — Predictive Biomarker (PRD): Multidrug resistance protein 1
Genes: ABCB1; MDR1; PGY1
Study NCT00164463 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00900627 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01306565 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03428061 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03428061 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT03967938 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study NCT03967938 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study NCT03967938 — Predictive Biomarker (PRD): Homologous recombination deficiency
Study NCT01545362 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study NCT04443907 — Predictive Biomarker (PRD): BCL11A mRNA
Genes: BCL11A; CTIP1; EVI9; KIAA1809; ZNF856
Study NCT00001184 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT01857934 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01857934 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04053296 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study NCT00502307 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03374839 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study NCT04199741 — Predictive Biomarker (PRD): DLL3 mRNA
Genes: DLL3
Study NCT03617198 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03617198 — Predictive Biomarker (PRD): CCR5 mRNA
Genes: CCR5; CMKBR5
Study NCT03147092 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02891590 — Pharmacodynamic Biomarker (PDY): Tyrosine-protein kinase BTK
Genes: BTK; AGMX1; ATK; BPK
Study NCT04307602 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study NCT04307602 — Predictive Biomarker (PRD): Nerve growth factor
Genes: NGF; NGFB
Study NCT04307602 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04307602 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01290016 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03503838 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01608269 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT01208337 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study NCT00841191 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00841191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study NCT02492802 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT00004225 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study NCT03832361 — Predictive Biomarker (PRD): Folate receptor alpha
Genes: FOLR1; FOLR
Study NCT01527578 — Predictive Biomarker (PRD): VIP mRNA
Genes: VIP
Study NCT01212263 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study NCT03891784 — Predictive Biomarker (PRD): CDK4 mRNA
Genes: CDK4
Study NCT00615602 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT03916861 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02807987 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT02807987 — Surrogate Endpoint (SUR): Blood pressure
Study NCT01526174 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04974502 — Monitoring Biomarker (MOI): Matrix metalloproteinase 8
Genes: MMP8; CLG1
Study NCT04974502 — Surrogate Endpoint (SUR): Probing pocket depth
Study NCT04117061 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study NCT04625569 — Surrogate Endpoint (SUR): Serum uric acid
Study NCT01554007 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study NCT01554007 — Predictive Biomarker (PRD): ACAD8 mRNA
Genes: ACAD8; ARC42; IBD
Study NCT01554007 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT01655654 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00099424 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00481754 — Predictive Biomarker (PRD): Phosphatase and tensin homolog
Genes: PTEN; MMAC1; TEP1
Study NCT00413140 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study NCT00413140 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT00413140 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT04084080 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study NCT02364713 — Predictive Biomarker (PRD): SLC5A5 mRNA
Genes: SLC5A5; NIS
Study NCT01446029 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02010190 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study NCT02010190 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT02010190 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study NCT02184897 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT00147563 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03877692 — Surrogate Endpoint (SUR): Blood pressure
Study NCT00283608 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study NCT01424761 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study NCT04178850 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT03086122 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT03086122 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03956784 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study NCT03730363 — Predictive Biomarker (PRD): Lymphocyte activation antigen CD30
Genes: TNFRSF8; CD30; D1S166E
Study NCT03730363 — Predictive Biomarker (PRD): CCL17 mRNA
Genes: CCL17; SCYA17; TARC
Study NCT03730363 — Monitoring Biomarker (MOI): Cell-free DNA
Study NCT00809250 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study NCT01096173 — Predictive Biomarker (PRD): PICALM mRNA
Genes: PICALM; CALM
Study NCT01669434 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study NCT01669434 — Surrogate Endpoint (SUR): Blood pressure
Study NCT03646292 — Predictive Biomarker (PRD): SLC5A2 mRNA
Genes: SLC5A2; SGLT2
Study NCT02532244 — Pharmacodynamic Biomarker (PDY): Survival motor neuron protein
Genes: SMN1; SMN; SMNT;; SMN2; SMNC
Study NCT03490864 — Surrogate Endpoint (SUR): Blood pressure
Study NCT02037763 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study NCT03787758 — Predictive Biomarker (PRD): SAGE1 mRNA
Genes: SAGE1; SAGE
Study NCT02815566 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03535363 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT03289065 — Predictive Biomarker (PRD): FOS mRNA
Genes: FOS; G0S7
Study NCT00003009 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study NCT03679598 — Predictive Biomarker (PRD): SERPINA1 mRNA
Genes: SERPINA1; AAT; PI; PRO0684; PRO2209
Study NCT01639911 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT02616627 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor 23
Genes: FGF23; HYPF; UNQ3027/PRO9828
Study NCT02616627 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02507492 — Predictive Biomarker (PRD): POMC mRNA
Genes: POMC
Study NCT02507492 — Surrogate Endpoint (SUR): Blood pressure
Study NCT05100602 — Predictive Biomarker (PRD): TERT mRNA
Genes: TERT; EST2; TCS1; TRT
Study NCT01203267 — Surrogate Endpoint (SUR): Pathological complete response
Study NCT00884637 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study NCT01477476 — Safety Biomarker (SAF): Interleukin 1
Study NCT01747135 — Predictive Biomarker (PRD): NPC1 mRNA
Genes: NPC1
Study NCT00350753 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study NCT00350753 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT04794920 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT02226289 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02226289 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT02861300 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study NCT03587493 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study NCT03587493 — Predictive Biomarker (PRD): CD38 mRNA
Genes: CD38
Study NCT03587493 — Predictive Biomarker (PRD): CCR7 mRNA
Genes: CCR7; CMKBR7; EBI1; EVI1
Study NCT03587493 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study NCT03587493 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT01107093 — Surrogate Endpoint (SUR): Serum luteinizing hormone
Study NCT04678856 — Pharmacodynamic Biomarker (PDY): Antidrug antibody
Study NCT03350828 — Predictive Biomarker (PRD): CFTR mRNA
Genes: CFTR; ABCC7
Study NCT02958761 — Safety Biomarker (SAF): Hyaluronic acid
Study NCT04619680 — Predictive Biomarker (PRD): SARS1 mRNA
Genes: SARS1; SARS; SERS
Study NCT01316692 — Predictive Biomarker (PRD): Aurora kinase A
Genes: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6
Study NCT00080392 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT00080392 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT01908556 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study NCT01908556 — Predictive Biomarker (PRD): CYP19A1 mRNA
Genes: CYP19A1; ARO1; CYAR; CYP19
Study NCT01414933 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study NCT01414933 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study NCT01414933 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study NCT03006536 — Predictive Biomarker (PRD): PDE5A mRNA
Genes: PDE5A; PDE5
Study NCT03910231 — Predictive Biomarker (PRD): AVPR2 mRNA
Genes: AVPR2; ADHR; DIR; DIR3; V2R
Study NCT03428412 — Predictive Biomarker (PRD); Safety Biomarker (SAF): CAT mRNA
Genes: CAT
Study NCT02139215 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study NCT00584584 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study NCT03733444 — Surrogate Endpoint (SUR): Forced vital capacity
Study NCT02303340 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT02198456 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study NCT01686269 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study NCT02944617 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study NCT02944617 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study NCT00555113 — Predictive Biomarker (PRD): ABCC6 mRNA
Genes: ABCC6; ARA; MRP6
Study NCT06209983 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study NCT03612232 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study NCT03612232 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Hepatocyte growth factor
Genes: HGF; HPTA
Study NCT01235325 — Surrogate Endpoint (SUR): Bone mineral density
Study NCT03173417 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study NCT04232007 — Surrogate Endpoint (SUR): Blood pressure
Study NCT04646980 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study NCT04646980 — Predictive Biomarker (PRD): IFIH1 mRNA
Genes: IFIH1; MDA5; RH116
Study NCT04646980 — Predictive Biomarker (PRD): ISG15 mRNA
Genes: ISG15; G1P2; UCRP
Study NCT04646980 — Predictive Biomarker (PRD): MX1 mRNA
Genes: MX1
Study NCT04646980 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study NCT00111397 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF