TrialPanorama/TrialPanorama-database huggingface dataset:
Study 19631948 — Predictive Biomarker (PRD): MYRF mRNA
Genes: MYRF; C11orf9; KIAA0954; MRF
Study 12503699 — Predictive Biomarker (PRD): MCC mRNA
Genes: MCC
Study 10519734 — Pharmacodynamic Biomarker (PDY): Cholesteryl ester transfer protein
Genes: CETP
Study 10519734 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7734901 — Surrogate Endpoint (SUR): Blood pressure
Study 28500784 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 28301205 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Metalloproteinase inhibitor 1
Genes: TIMP1; CLGI; TIMP
Study 28301205 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 18299546 — Surrogate Endpoint (SUR): Bone mineral density
Study 12953165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12953165 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 10793603 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1282428 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 1282428 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 30642076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 30373740 — Safety Biomarker (SAF): Interleukin 18
Genes: IL18; IGIF; IL1F4
Study 30373740 — Surrogate Endpoint (SUR): Serum creatinine
Study 30373740 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30373740 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12040477 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 2548554 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 21787159 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21787159 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 19549125 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 26666342 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 26666342 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26666342 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 20642545 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17715164 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2523611 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 2523611 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 11249051 — Predictive Biomarker (PRD): CD34 mRNA
Genes: CD34
Study 7940765 — Surrogate Endpoint (SUR): Blood pressure
Study 21118164 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 18708685 — Surrogate Endpoint (SUR): Blood pressure
Study 8870441 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 2000817 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25169631 — Predictive Biomarker (PRD): PAH mRNA
Genes: PAH
Study 17409306 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 22453248 — Predictive Biomarker (PRD): RPE mRNA
Genes: RPE; HUSSY-17
Study 7675585 — Surrogate Endpoint (SUR): Blood pressure
Study 27220348 — Surrogate Endpoint (SUR): Serum creatinine
Study 25218783 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 15193818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15193818 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15193818 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25529033 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25529033 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 27902612 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 12584575 — Surrogate Endpoint (SUR): Blood pressure
Study 9690944 — Surrogate Endpoint (SUR): Serum creatinine
Study 8080985 — Predictive Biomarker (PRD): SCD mRNA
Genes: SCD; FADS5; SCD1; SCDOS
Study 2753986 — Predictive Biomarker (PRD): PBX1 mRNA
Genes: PBX1; PRL
Study 20804630 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14983613 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 30368584 — Predictive Biomarker (PRD): FGFR4 mRNA
Genes: FGFR4; JTK2; TKF
Study 30368584 — Pharmacodynamic Biomarker (PDY): Fibroblast growth factor receptor
Study 29901710 — Surrogate Endpoint (SUR): Blood pressure
Study 29901710 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18807577 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 18807577 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 18807577 — Surrogate Endpoint (SUR): Blood pressure
Study 21106625 — Surrogate Endpoint (SUR): Blood pressure
Study 7945600 — Surrogate Endpoint (SUR): Blood pressure
Study 12528545 — Surrogate Endpoint (SUR): Blood pressure
Study 22763801 — Surrogate Endpoint (SUR): Blood pressure
Study 11907289 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 11763947 — Predictive Biomarker (PRD): NAT9 mRNA
Genes: NAT9; EBS
Study 8964851 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 29409728 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17432075 — Surrogate Endpoint (SUR): Blood pressure
Study 15910732 — Predictive Biomarker (PRD): GDA mRNA
Genes: GDA; KIAA1258
Study 7999930 — Surrogate Endpoint (SUR): Blood pressure
Study 24521629 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 22704426 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 28103841 — Surrogate Endpoint (SUR): Exhaled carbon monoxide
Study 28103841 — Surrogate Endpoint (SUR): Blood pressure
Study 18783735 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 14740329 — Surrogate Endpoint (SUR): Serum calcium
Study 20482894 — Surrogate Endpoint (SUR): Bone mineral density
Study 16210834 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 16210834 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 29862491 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 25772196 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 17719702 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17719702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 7020917 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 26492082 — Predictive Biomarker (PRD): TYR mRNA
Genes: TYR
Study 26492082 — Pharmacodynamic Biomarker (PDY): Error related negativity
Study 24196866 — Surrogate Endpoint (SUR): Serum creatinine
Study 19777852 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19777852 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22380577 — Surrogate Endpoint (SUR): Bone mineral density
Study 16160589 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 30197644 — Surrogate Endpoint (SUR): Serum creatinine
Study 8018766 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 22398880 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19684384 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 10412851 — Surrogate Endpoint (SUR): Probing pocket depth
Study 2321778 — Surrogate Endpoint (SUR): Blood pressure
Study 31921170 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30225882 — Surrogate Endpoint (SUR): Blood pressure
Study 25439415 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 25439415 — Surrogate Endpoint (SUR): Blood pressure
Study 7341284 — Surrogate Endpoint (SUR): Serum uric acid
Study 29571566 — Surrogate Endpoint (SUR): Serum potassium
Study 22494623 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Mucin-1
Genes: MUC1; PUM
Study 20193521 — Surrogate Endpoint (SUR): Blood pressure
Study 23424215 — Surrogate Endpoint (SUR): Blood pressure
Study 10682136 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 28544774 — Predictive Biomarker (PRD): TPO mRNA
Genes: TPO
Study 23313564 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 23313564 — Safety Biomarker (SAF): BDNF
Study 15975966 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10856268 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 9379646 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 9379646 — Predictive Biomarker (PRD): PNP mRNA
Genes: PNP; NP
Study 10908083 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 1471603 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 6327758 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25417935 — Predictive Biomarker (PRD): TES mRNA
Genes: TES
Study 24350806 — Surrogate Endpoint (SUR): Blood pressure
Study 21981375 — Predictive Biomarker (PRD): OGT mRNA
Genes: OGT
Study 17726080 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 15922817 — Surrogate Endpoint (SUR): Blood pressure
Study 1909273 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 18341819 — Surrogate Endpoint (SUR): Blood pressure
Study 16343101 — Surrogate Endpoint (SUR): Blood pressure
Study 11382891 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11382891 — Predictive Biomarker (PRD): CD5 mRNA
Genes: CD5; LEU1
Study 11382891 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 11382891 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 7787395 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Adrenomedullin
Genes: ADM; AM
Study 21870665 — Surrogate Endpoint (SUR): Blood pressure
Study 11792410 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10626026 — Surrogate Endpoint (SUR): Blood pressure
Study 7485849 — Surrogate Endpoint (SUR): Blood pressure
Study 31515735 — Surrogate Endpoint (SUR): Blood pressure
Study 30012822 — Surrogate Endpoint (SUR): Blood pressure
Study 18386234 — Predictive Biomarker (PRD): DAP mRNA
Genes: DAP; DAP1
Study 479383 — Surrogate Endpoint (SUR): Blood pressure
Study 16098067 — Predictive Biomarker (PRD): DDIT3 mRNA
Genes: DDIT3; CHOP; CHOP10; GADD153
Study 16244488 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 176034 — Predictive Biomarker (PRD): NR3C2 mRNA
Genes: NR3C2; MCR; MLR
Study 28540870 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28540870 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28540870 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 26189154 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 9543129 — Surrogate Endpoint (SUR): Bone mineral density
Study 10155484 — Surrogate Endpoint (SUR): Blood pressure
Study 2724504 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 2724504 — Surrogate Endpoint (SUR): Blood pressure
Study 24195206 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 16357613 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31172821 — Safety Biomarker (SAF): Hyaluronic acid
Study 27459523 — Predictive Biomarker (PRD): TBXT mRNA
Genes: TBXT; T
Study 20304503 — Predictive Biomarker (PRD): IDS mRNA
Genes: IDS; SIDS
Study 19029275 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 10873425 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10873425 — Predictive Biomarker (PRD): CD68 mRNA
Genes: CD68
Study 10873425 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 8884648 — Safety Biomarker (SAF): Interleukin 1
Study 8884648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1857534 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 1857534 — Surrogate Endpoint (SUR): Serum calcium
Study 31859138 — Predictive Biomarker (PRD): MVD mRNA
Genes: MVD; MPD
Study 26076757 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 26112176 — Predictive Biomarker (PRD): EMP1 mRNA
Genes: EMP1; B4B; TMP
Study 23731922 — Predictive Biomarker (PRD): MB mRNA
Genes: MB
Study 7845867 — Predictive Biomarker (PRD); Safety Biomarker (SAF): DES mRNA
Genes: DES
Study 31254481 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 19129280 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 17472820 — Surrogate Endpoint (SUR): Blood pressure
Study 15262126 — Monitoring Biomarker (MOI): Ovarian carcinoma antigen CA125
Genes: MUC16; CA125
Study 10682563 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 2474097 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31371341 — Predictive Biomarker (PRD): PTPRC mRNA
Genes: PTPRC; CD45
Study 31371341 — Safety Biomarker (SAF): Hemoglobin scavenger receptor
Genes: CD163; M130
Study 31371341 — Predictive Biomarker (PRD): Proto-oncogene c-Met
Genes: MET
Study 27893563 — Surrogate Endpoint (SUR): Blood pressure
Study 27893563 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10617941 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 31344268 — Surrogate Endpoint (SUR): Blood pressure
Study 29064536 — Surrogate Endpoint (SUR): Blood pressure
Study 15906109 — Safety Biomarker (SAF): Hyaluronic acid
Study 10516734 — Surrogate Endpoint (SUR): Blood pressure
Study 27407058 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 10450297 — Surrogate Endpoint (SUR): Blood pressure
Study 31341122 — Predictive Biomarker (PRD): AR mRNA
Genes: AR; DHTR; NR3C4
Study 7572690 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 471153 — Surrogate Endpoint (SUR): Blood pressure
Study 471153 — Surrogate Endpoint (SUR): Serum uric acid
Study 30680830 — Surrogate Endpoint (SUR): Blood pressure
Study 29283132 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 16883916 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Complement C3
Genes: C3; CPAMD1
Study 12832308 — Monitoring Biomarker (MOI): Adenosine deaminase
Genes: ADA; ADA1
Study 12832308 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8867520 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 1638712 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27394149 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 27394149 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18372701 — Surrogate Endpoint (SUR): Blood pressure
Study 15164322 — Surrogate Endpoint (SUR): Bone mineral density
Study 31911640 — Surrogate Endpoint (SUR): Forced vital capacity
Study 3018561 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29466862 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 29466862 — Monitoring Biomarker (MOI): HBV DNA
Study 25564105 — Predictive Biomarker (PRD): COMMD3 mRNA
Genes: COMMD3; BUP; C10orf8
Study 16612281 — Surrogate Endpoint (SUR): Serum creatinine
Study 16612281 — Surrogate Endpoint (SUR): Blood pressure
Study 27413037 — Surrogate Endpoint (SUR): Blood pressure
Study 29614521 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 29614521 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 1556522 — Surrogate Endpoint (SUR): Serum triglycerides
Study 1556522 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 25260632 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 22270198 — Predictive Biomarker (PRD): DCN mRNA
Genes: DCN; SLRR1B
Study 12776276 — Surrogate Endpoint (SUR): Hematologic response
Study 24284361 — Predictive Biomarker (PRD): LDLR mRNA
Genes: LDLR
Study 24284361 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 22432114 — Surrogate Endpoint (SUR): Serum creatinine
Study 22432114 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 29275795 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HP mRNA
Genes: HP
Study 21925346 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 25855628 — Predictive Biomarker (PRD): HPSE mRNA
Genes: HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1
Study 22763799 — Pharmacodynamic Biomarker (PDY): Serum phosphate
Study 11596665 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11596665 — Surrogate Endpoint (SUR): Blood pressure
Study 25023798 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 18572334 — Predictive Biomarker (PRD): ASRGL1 mRNA
Genes: ASRGL1; ALP; CRASH
Study 18572334 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 18572334 — Surrogate Endpoint (SUR): Bone mineral density
Study 18572334 — Surrogate Endpoint (SUR): Serum alkaline phosphatase
Study 25927224 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 22170177 — Predictive Biomarker (PRD): S100B mRNA
Genes: S100B
Study 16003061 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7496933 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 2683263 — Surrogate Endpoint (SUR): Serum creatinine
Study 29962339 — Predictive Biomarker (PRD): SLC12A3 mRNA
Genes: SLC12A3; NCC; TSC
Study 29962339 — Predictive Biomarker (PRD): DCT mRNA
Genes: DCT; TYRP2
Study 18376350 — Pharmacodynamic Biomarker (PDY): Gastric inhibitory polypeptide
Genes: GIP
Study 28913846 — Surrogate Endpoint (SUR): Blood pressure
Study 28913846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 28913846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28913846 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18623166 — Surrogate Endpoint (SUR): Bone mineral density
Study 3064333 — Surrogate Endpoint (SUR): Probing pocket depth
Study 19114761 — Surrogate Endpoint (SUR): Blood pressure
Study 26839145 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26839145 — Pharmacodynamic Biomarker (PDY): Signal transducer and activator of transcription 3
Genes: STAT3; APRF
Study 24715424 — Predictive Biomarker (PRD): PYY mRNA
Genes: PYY
Study 8052432 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 8052432 — Surrogate Endpoint (SUR): Blood pressure
Study 27838576 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 21555689 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 19412127 — Surrogate Endpoint (SUR): Serum creatinine
Study 30788892 — Surrogate Endpoint (SUR): Forced vital capacity
Study 28336937 — Surrogate Endpoint (SUR): Minimal residual disease response rate
Study 19329405 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19329405 — Surrogate Endpoint (SUR): Blood pressure
Study 16394956 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 16394956 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12801491 — Predictive Biomarker (PRD): PCSK5 mRNA
Genes: PCSK5; PC5; PC6
Study 30739376 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25511794 — Predictive Biomarker (PRD): CES1 mRNA
Genes: CES1; CES2; SES1
Study 21495829 — Surrogate Endpoint (SUR): Blood pressure
Study 15323587 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 7267929 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29065076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29065076 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29065076 — Surrogate Endpoint (SUR): Blood pressure
Study 28623122 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 28623122 — Safety Biomarker (SAF): PDCD1
Genes: CD279; PD1; hSLE1; PD-1
Study 27927226 — Surrogate Endpoint (SUR): Blood pressure
Study 22843087 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 22843087 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 9825816 — Surrogate Endpoint (SUR): Blood pressure
Study 9825816 — Surrogate Endpoint (SUR): Serum creatinine
Study 19750190 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 29725191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29725191 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29725191 — Surrogate Endpoint (SUR): Blood pressure
Study 24931702 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24931702 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 18793543 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 18793543 — Surrogate Endpoint (SUR): Serum creatinine
Study 27964826 — Predictive Biomarker (PRD): MSC mRNA
Genes: MSC; ABF1; BHLHA22