TrialPanorama/TrialPanorama-database huggingface dataset:
Study 17644511 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 12358921 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 19770778 — Surrogate Endpoint (SUR): Blood pressure
Study 17570265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 17570265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 17570265 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 382433 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 382433 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 31335572 — Surrogate Endpoint (SUR): Hemagglutination inhibition antibody
Study 26192873 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30383458 — Predictive Biomarker (PRD): SRI mRNA
Genes: SRI
Study 21340377 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 18181252 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 18181252 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 11092517 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11092517 — Surrogate Endpoint (SUR): Blood pressure
Study 1957968 — Predictive Biomarker (PRD); Safety Biomarker (SAF): FLNA mRNA
Genes: FLNA; FLN; FLN1
Study 6274476 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 25811674 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 9663476 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 9663476 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 9663476 — Safety Biomarker (SAF): CDA
Genes: CDD
Study 31188820 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 31188820 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31188820 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16449030 — Pharmacodynamic Biomarker (PDY): Transmembrane glycoprotein NMB
Genes: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
Study 4018467 — Surrogate Endpoint (SUR): Blood pressure
Study 17637912 — Surrogate Endpoint (SUR): Blood pressure
Study 10460529 — Surrogate Endpoint (SUR): Blood pressure
Study 30824825 — Surrogate Endpoint (SUR): Blood pressure
Study 16733624 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 16733624 — Surrogate Endpoint (SUR): Bone mineral density
Study 2872806 — Surrogate Endpoint (SUR): Blood pressure
Study 30458866 — Predictive Biomarker (PRD): LAMA1 mRNA
Genes: LAMA1; LAMA
Study 24377455 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24377455 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22210566 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): BDNF mRNA
Genes: BDNF
Study 22210566 — Safety Biomarker (SAF): BDNF
Study 22210566 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 8949694 — Predictive Biomarker (PRD): LCT mRNA
Genes: LCT; LPH
Study 1827008 — Surrogate Endpoint (SUR): Blood pressure
Study 31563697 — Predictive Biomarker (PRD): AMH mRNA
Genes: AMH; MIF
Study 25907781 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 25907781 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 6475754 — Surrogate Endpoint (SUR): Blood pressure
Study 6475754 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 6475754 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 25113081 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 25113081 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 25113081 — Safety Biomarker (SAF): IL-6 and IL-10
Study 22190134 — Surrogate Endpoint (SUR): Bone mineral density
Study 21044831 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 16788927 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 12011968 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2666451 — Surrogate Endpoint (SUR): Blood pressure
Study 27581812 — Surrogate Endpoint (SUR): Blood pressure
Study 23278574 — Safety Biomarker (SAF): DHFR
Genes: DHFR1
Study 20016142 — Surrogate Endpoint (SUR): Serum calcium
Study 20016142 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 7889438 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 19767074 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 3538945 — Surrogate Endpoint (SUR): Blood pressure
Study 30205371 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 30205371 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 24337154 — Predictive Biomarker (PRD): TLR3 mRNA
Genes: TLR3
Study 24337154 — Predictive Biomarker (PRD): TLR4 mRNA
Genes: TLR4
Study 24337154 — Predictive Biomarker (PRD): TLR5 mRNA
Genes: TLR5; TIL3
Study 24337154 — Predictive Biomarker (PRD): MAP4K4 mRNA
Genes: MAP4K4; HGK; KIAA0687; NIK
Study 24337154 — Predictive Biomarker (PRD): MAP2K3 mRNA
Genes: MAP2K3; MEK3; MKK3; PRKMK3; SKK2
Study 24337154 — Predictive Biomarker (PRD): CHUK mRNA
Genes: CHUK; IKKA; TCF16
Study 24337154 — Predictive Biomarker (PRD): CHUK
Genes: IKK1; IKK-alpha; IkBKA; NFKBIKA; IKKA
Study 24337154 — Predictive Biomarker (PRD): REL mRNA
Genes: REL
Study 24337154 — Predictive Biomarker (PRD): RELA mRNA
Genes: RELA; NFKB3
Study 11914161 — Predictive Biomarker (PRD): KCNIP3 mRNA
Genes: KCNIP3; CSEN; DREAM; KCHIP3
Study 19521070 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19521070 — Surrogate Endpoint (SUR): Serum calcium
Study 11159234 — Pharmacodynamic Biomarker (PDY): Heat pain threshold
Study 8781301 — Predictive Biomarker (PRD): HGD mRNA
Genes: HGD; HGO
Study 1352496 — Surrogate Endpoint (SUR): Blood pressure
Study 6496393 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 6496393 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31601569 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 31601569 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19491556 — Safety Biomarker (SAF): Ornithine transcarbamylase
Genes: OTC
Study 9428829 — Surrogate Endpoint (SUR): Bone mineral density
Study 8512094 — Surrogate Endpoint (SUR): Blood pressure
Study 18698246 — Predictive Biomarker (PRD): MAL mRNA
Genes: MAL
Study 15713351 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 9524014 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 27503233 — Predictive Biomarker (PRD): FUT2 mRNA
Genes: FUT2; SEC2
Study 23620429 — Predictive Biomarker (PRD): AMD1 mRNA
Genes: AMD1; AMD
Study 21679357 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 1377306 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 1377306 — Surrogate Endpoint (SUR): Blood pressure
Study 23018440 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 23018440 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 12564742 — Surrogate Endpoint (SUR): Blood pressure
Study 11200748 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11200748 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 25463450 — Predictive Biomarker (PRD): PHLDA2 mRNA
Genes: PHLDA2; BWR1C; HLDA2; IPL; TSSC3
Study 21232664 — Predictive Biomarker (PRD): TAT mRNA
Genes: TAT
Study 19235536 — Predictive Biomarker (PRD): PC mRNA
Genes: PC
Study 1020902 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 31630117 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 27469171 — Predictive Biomarker (PRD): TNFRSF11B mRNA
Genes: TNFRSF11B; OCIF; OPG
Study 11746863 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11746863 — Safety Biomarker (SAF): Reactive oxygen species
Study 23525499 — Predictive Biomarker (PRD): ALDH2 mRNA
Genes: ALDH2; ALDM
Study 18239561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 18239561 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 8819106 — Predictive Biomarker (PRD): CD69 mRNA
Genes: CD69; CLEC2C
Study 8819106 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8819106 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16793562 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 16793562 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 7472905 — Surrogate Endpoint (SUR): Serum calcium
Study 26255764 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9778719 — Surrogate Endpoint (SUR): Blood pressure
Study 7709944 — Surrogate Endpoint (SUR): Bone mineral density
Study 16464386 — Surrogate Endpoint (SUR): Serum creatinine
Study 16464386 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 30236136 — Surrogate Endpoint (SUR): Serum calcium
Study 20042092 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16036076 — Surrogate Endpoint (SUR): Bone mineral density
Study 11451272 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 21407247 — Predictive Biomarker (PRD): PON1 mRNA
Genes: PON1; PON
Study 21407247 — Monitoring Biomarker (MOI): Apolipoprotein A-IV
Genes: APOA4
Study 17925087 — Surrogate Endpoint (SUR): Cervical intraepithelial neoplasia
Study 30589600 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 28322071 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28322071 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 14693409 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 18068888 — Surrogate Endpoint (SUR): Blood pressure
Study 14693167 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 14693167 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 29351736 — Surrogate Endpoint (SUR): Blood pressure
Study 17986525 — Pharmacodynamic Biomarker (PDY): Dipeptidyl peptidase 4
Genes: DPP4; ADCP2; CD26
Study 17986525 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 10524687 — Predictive Biomarker (PRD): ACR mRNA
Genes: ACR; ACRS
Study 8523876 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 29723896 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 28182863 — Surrogate Endpoint (SUR): Blood pressure
Study 9605897 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 2608693 — Surrogate Endpoint (SUR): Blood pressure
Study 25724520 — Predictive Biomarker (PRD): PIK3CA mRNA
Genes: PIK3CA
Study 25724520 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 25724520 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 25724520 — Safety Biomarker (SAF): Serine/threonine-protein kinase STK11
Genes: STK11
Study 25724520 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PIK3CA
Genes: PI3K
Study 18446392 — Surrogate Endpoint (SUR): Blood pressure
Study 29310653 — Surrogate Endpoint (SUR): Blood pressure
Study 9568553 — Surrogate Endpoint (SUR): Blood pressure
Study 3055074 — Surrogate Endpoint (SUR): Blood pressure
Study 30715100 — Surrogate Endpoint (SUR): Blood pressure
Study 28398499 — Predictive Biomarker (PRD): MYC mRNA
Genes: MYC; BHLHE39
Study 28398499 — Safety Biomarker (SAF): Beta-2-microglobulin
Genes: B2M; CDABP0092; HDCMA22P
Study 15295613 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 15295613 — Surrogate Endpoint (SUR): Blood pressure
Study 11306743 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 26030423 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 26030423 — Predictive Biomarker (PRD): AKT1 mRNA
Genes: AKT1; PKB; RAC
Study 26030423 — Predictive Biomarker (PRD): NKRF mRNA
Genes: NKRF; ITBA4; NRF
Study 23562361 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 19622708 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 15582080 — Predictive Biomarker (PRD): PVR mRNA
Genes: PVR; PVS
Study 29301585 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 21792863 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 17244770 — Pharmacodynamic Biomarker (PDY): Angiotensinogenase renin
Genes: REN
Study 7894551 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31618863 — Predictive Biomarker (PRD): CCK mRNA
Genes: CCK
Study 27829249 — Predictive Biomarker (PRD): TNFRSF6B
Genes: DcR3; DCR3; TR6; M68
Study 27829249 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Trefoil factor 3
Genes: TFF3; ITF; TFI
Study 21673045 — Predictive Biomarker (PRD): PPT1 mRNA
Genes: PPT1; CLN1; PPT
Study 19843683 — Predictive Biomarker (PRD): BRCA1 mRNA
Genes: BRCA1; RNF53
Study 2439808 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 2439808 — Surrogate Endpoint (SUR): Blood pressure
Study 29861725 — Predictive Biomarker (PRD): Angiopoietin-related protein 4
Genes: ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197
Study 15987865 — Surrogate Endpoint (SUR): Blood pressure
Study 7546498 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 7546498 — Surrogate Endpoint (SUR): Blood pressure
Study 43950 — Surrogate Endpoint (SUR): Blood pressure
Study 28618005 — Pharmacodynamic Biomarker (PDY): Beta-secretase 1
Genes: BACE1; BACE; KIAA1149
Study 25243731 — Surrogate Endpoint (SUR): Blood pressure
Study 23534542 — Predictive Biomarker (PRD); Safety Biomarker (SAF): miR-122
Genes: MIR122
Study 16519546 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30101300 — Surrogate Endpoint (SUR): Blood pressure
Study 20646599 — Surrogate Endpoint (SUR): Blood pressure
Study 18700689 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 12418497 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 31804580 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31804580 — Surrogate Endpoint (SUR): Blood pressure
Study 16969894 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 5411446 — Surrogate Endpoint (SUR): Blood pressure
Study 2790695 — Predictive Biomarker (PRD): Estrogen receptor
Genes: ESR1; ESR; NR3A1
Study 30796973 — Predictive Biomarker (PRD): GAD1 mRNA
Genes: GAD1; GAD; GAD67
Study 27557955 — Predictive Biomarker (PRD): MIA mRNA
Genes: MIA
Study 23825422 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 23825422 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 21707983 — Surrogate Endpoint (SUR): Blood pressure
Study 23595408 — Predictive Biomarker (PRD): CP mRNA
Genes: CP
Study 17043614 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 9249230 — Surrogate Endpoint (SUR): Blood pressure
Study 9249230 — Surrogate Endpoint (SUR): Serum calcium
Study 29505744 — Predictive Biomarker (PRD): FES mRNA
Genes: FES; FPS
Study 18035196 — Surrogate Endpoint (SUR): Blood pressure
Study 327758 — Surrogate Endpoint (SUR): Serum triglycerides
Study 20101512 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 20101512 — Surrogate Endpoint (SUR): Blood pressure
Study 10421219 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10421219 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 26574566 — Surrogate Endpoint (SUR): Blood pressure
Study 9564795 — Surrogate Endpoint (SUR): Bone mineral density
Study 9564795 — Surrogate Endpoint (SUR): Serum calcium
Study 2275909 — Surrogate Endpoint (SUR): Forced vital capacity
Study 25828038 — Safety Biomarker (SAF): Hyaluronic acid
Study 21434334 — Monitoring Biomarker (MOI): Procalcitonin
Study 15231854 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 31714573 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 22480099 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 9786163 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Endothelin-1
Genes: EDN1
Study 9786163 — Surrogate Endpoint (SUR): Blood pressure
Study 25545196 — Predictive Biomarker (PRD); Safety Biomarker (SAF): PSD mRNA
Genes: PSD; EFA6; EFA6A; KIAA2011; PSD1; TYL
Study 20875492 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 20875492 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 16824833 — Predictive Biomarker (PRD): ACAT1 mRNA
Genes: ACAT1; ACAT; MAT
Study 29984912 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 19385713 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 2096487 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 2096487 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 361201 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 24267042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 24267042 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 24267042 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 28592386 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 28592386 — Surrogate Endpoint (SUR): Pathological complete response
Study 1316885 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 20108040 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 29896813 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 29896813 — Predictive Biomarker (PRD): CFH mRNA
Genes: CFH; HF; HF1; HF2
Study 29896813 — Surrogate Endpoint (SUR): Blood pressure
Study 27289122 — Surrogate Endpoint (SUR): Blood pressure
Study 22089534 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 20435205 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 17368974 — Surrogate Endpoint (SUR): Blood pressure
Study 10485423 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 17573736 — Surrogate Endpoint (SUR): Blood pressure
Study 6734051 — Surrogate Endpoint (SUR): Blood pressure
Study 31490959 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 31490959 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 29297472 — Surrogate Endpoint (SUR): Blood pressure
Study 27141838 — Predictive Biomarker (PRD): LPP mRNA
Genes: LPP
Study 21313901 — Predictive Biomarker (PRD): TG mRNA
Genes: TG
Study 28739766 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 23161902 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 21606190 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Free fatty acids
Study 21050483 — Surrogate Endpoint (SUR): Bone mineral density
Study 14741065 — Surrogate Endpoint (SUR): Blood pressure
Study 8406655 — Surrogate Endpoint (SUR): Blood pressure
Study 23095630 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 15896585 — Surrogate Endpoint (SUR): Blood pressure
Study 12169868 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12169868 — Surrogate Endpoint (SUR): Blood pressure
Study 12169868 — Surrogate Endpoint (SUR): Serum creatinine
Study 9802752 — Safety Biomarker (SAF): von Willebrand factor
Genes: VWF; F8VWF
Study 9802752 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 31227804 — Predictive Biomarker (PRD): NUCB2 mRNA
Genes: NUCB2; NEFA
Study 31227804 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 31227804 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 27461166 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 2 receptor alpha
Genes: IL2RA
Study 27461166 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 10595697 — Surrogate Endpoint (SUR): Blood pressure
Study 28887907 — Predictive Biomarker (PRD): CGA mRNA
Genes: CGA
Study 22249353 — Predictive Biomarker (PRD): HPR mRNA
Genes: HPR
Study 16128596 — Safety Biomarker (SAF): Reactive oxygen species
Study 16128596 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Matrix metalloproteinase 3
Genes: MMP3; STMY1
Study 16128596 — Safety Biomarker (SAF): MMP-1
Genes: MMP1
Study 10194083 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 8789567 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 8789567 — Safety Biomarker (SAF): Natriuretic peptides A
Genes: NPPA; ANP; PND
Study 6803692 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 6803692 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 6803692 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 17822748 — Predictive Biomarker (PRD): CS mRNA
Genes: CS
Study 2871952 — Predictive Biomarker (PRD): TRH mRNA
Genes: TRH
Study 31127363 — Predictive Biomarker (PRD): CTLA4
Genes: CD152; CD; GSE; CTLA-4
Study 15041612 — Surrogate Endpoint (SUR): Blood pressure
Study 9006882 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9006882 — Predictive Biomarker (PRD): SELENBP1 mRNA
Genes: SELENBP1; SBP
Study 9006882 — Surrogate Endpoint (SUR): Blood pressure
Study 8485071 — Surrogate Endpoint (SUR): Blood pressure
Study 30298202 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30298202 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 16300166 — Predictive Biomarker (PRD): EMD mRNA
Genes: EMD; EDMD; STA