TrialPanorama/TrialPanorama-database huggingface dataset:
Study 25566615 — Safety Biomarker (SAF): Biliary glycoprotein 1
Genes: CEACAM1; BGP; BGP1
Study 25566615 — Predictive Biomarker (PRD): DMD
Genes: BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
Study 25566615 — Surrogate Endpoint (SUR): Bone mineral density
Study 28671626 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 28671626 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 24491065 — Surrogate Endpoint (SUR): Blood pressure
Study 12029003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12029003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12029003 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 1653313 — Surrogate Endpoint (SUR): Serum potassium
Study 21441615 — Safety Biomarker (SAF): IL-6 and IL-10
Study 16318999 — Predictive Biomarker (PRD): GSTM1 mRNA
Genes: GSTM1; GST1
Study 354916 — Surrogate Endpoint (SUR): Blood pressure
Study 28681506 — Predictive Biomarker (PRD): TLR7 mRNA
Genes: TLR7; UNQ248/PRO285
Study 2493366 — Safety Biomarker (SAF): 51Cr-EDTA
Study 11704591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11704591 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 9415633 — Surrogate Endpoint (SUR): Bone mineral density
Study 29763783 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 15684311 — Predictive Biomarker (PRD): CCND1
Genes: U21B31
Study 12862418 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 30256747 — Predictive Biomarker (PRD): CPM mRNA
Genes: CPM
Study 27324887 — Surrogate Endpoint (SUR): Neutralizing antibody
Study 18260975 — Surrogate Endpoint (SUR): Blood pressure
Study 26001563 — Predictive Biomarker (PRD); Monitoring Biomarker (MOI): Interleukin 13
Genes: IL13; NC30
Study 21618158 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11350882 — Monitoring Biomarker (MOI): Carcinoembryonic antigen CEA
Genes: CEACAM5; CEA
Study 11350882 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 28395758 — Safety Biomarker (SAF): Dihydrothymine dehydrogenase
Genes: DPYD
Study 21165806 — Surrogate Endpoint (SUR): Blood pressure
Study 17008146 — Predictive Biomarker (PRD): GGT1 mRNA
Genes: GGT1; GGT
Study 28318835 — Pharmacodynamic Biomarker (PDY): Mismatch negativity
Study 28318835 — Pharmacodynamic Biomarker (PDY): Auditory mismatch negativity
Study 10427139 — Predictive Biomarker (PRD); Safety Biomarker (SAF): TP53
Genes: p53; LFS1
Study 12177657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 12177657 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 26318511 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 26318511 — Safety Biomarker (SAF): Cystatin C
Genes: CST3
Study 26318511 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 10556002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10556002 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 26735531 — Predictive Biomarker (PRD): PF4 mRNA
Genes: PF4; CXCL4; SCYB4
Study 26735531 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 22535548 — Surrogate Endpoint (SUR): Blood pressure
Study 24063843 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 14970111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 14970111 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11477352 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 9570178 — Surrogate Endpoint (SUR): Blood pressure
Study 28489032 — Surrogate Endpoint (SUR): Serum calcium
Study 28489032 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 28489032 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Lactate dehydrogenase
Study 23245622 — Predictive Biomarker (PRD): RHD mRNA
Genes: RHD
Study 14600188 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 1358134 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 22356216 — Safety Biomarker (SAF): RFC1
Genes: A1; PO-GA; RFC140; MHCBFB
Study 22356216 — Surrogate Endpoint (SUR): Blood pressure
Study 9604603 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 8040762 — Surrogate Endpoint (SUR): Bone mineral density
Study 24829204 — Predictive Biomarker (PRD): KLF1 mRNA
Genes: KLF1; EKLF
Study 22336631 — Predictive Biomarker (PRD): ADORA2A mRNA
Genes: ADORA2A; ADORA2
Study 22336631 — Predictive Biomarker (PRD): CYP1A2 mRNA
Genes: CYP1A2
Study 22336631 — Safety Biomarker (SAF): ADORA2A
Genes: RDC8
Study 16291468 — Predictive Biomarker (PRD): CCS mRNA
Genes: CCS
Study 11991447 — Surrogate Endpoint (SUR): Serum intact parathyroid hormone
Study 11991447 — Predictive Biomarker (PRD): Intact parathyroid hormone
Study 11991447 — Surrogate Endpoint (SUR): Bone mineral density
Study 2291869 — Surrogate Endpoint (SUR): Blood pressure
Study 6106039 — Surrogate Endpoint (SUR): Blood pressure
Study 9616533 — Surrogate Endpoint (SUR): Serum potassium
Study 9616533 — Surrogate Endpoint (SUR): Blood pressure
Study 6107585 — Predictive Biomarker (PRD): TF mRNA
Genes: TF; PRO1400
Study 30735073 — Surrogate Endpoint (SUR): Blood pressure
Study 29661563 — Predictive Biomarker (PRD): HMMR mRNA
Genes: HMMR; IHABP; RHAMM
Study 16778124 — Safety Biomarker (SAF): Arachidonate 5-lipoxygenase activating protein
Genes: ALOX5AP; FLAP
Study 8222487 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 8222487 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 31933345 — Surrogate Endpoint (SUR): Blood pressure
Study 31752638 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 31752638 — Surrogate Endpoint (SUR): Blood pressure
Study 31752638 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 22845614 — Surrogate Endpoint (SUR): Probing pocket depth
Study 17332962 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): D-dimer
Study 17332962 — Safety Biomarker (SAF): Antithrombin-III
Genes: SERPINC1; AT3; PRO0309
Study 11274583 — Surrogate Endpoint (SUR): Blood pressure
Study 21517801 — Safety Biomarker (SAF): Hyaluronic acid
Study 30702226 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 24231013 — Predictive Biomarker (PRD): SI mRNA
Genes: SI
Study 18923572 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 18923572 — Predictive Biomarker (PRD): FCGR3B
Genes: CD16; CD16b; FcgammaRIIIb; FcRIIIb
Study 18923572 — Predictive Biomarker (PRD): Leukocyte surface antigen Leu-16
Genes: MS4A1; CD20
Study 18923572 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 18923572 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 8704693 — Surrogate Endpoint (SUR): Bone mineral density
Study 24972254 — Surrogate Endpoint (SUR): Forced vital capacity
Study 16099352 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 11587995 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 11587995 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 11587995 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 7522287 — Surrogate Endpoint (SUR): Blood pressure
Study 26349433 — Surrogate Endpoint (SUR): Serum creatinine
Study 11015147 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22089378 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 15837982 — Predictive Biomarker (PRD): Hormone receptor
Study 7836705 — Monitoring Biomarker (MOI): HBV DNA
Study 17154786 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY): Microtubule-associated protein tau
Genes: MAPT; MAPTL; MTBT1; TAU
Study 1334792 — Surrogate Endpoint (SUR): Blood pressure
Study 12399272 — Surrogate Endpoint (SUR): Blood pressure
Study 10410487 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 7595709 — Safety Biomarker (SAF): Granulocyte-macrophage colony-stimulating factor
Genes: CSF2; GMCSF
Study 27911471 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 24142232 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22052267 — Safety Biomarker (SAF): Hyaluronic acid
Study 15531933 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 11125853 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 29024304 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 15866625 — Surrogate Endpoint (SUR): Blood pressure
Study 28624580 — Predictive Biomarker (PRD): HFE mRNA
Genes: HFE; HLAH
Study 19555036 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 19555036 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 16290998 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 25322173 — Predictive Biomarker (PRD): FURIN mRNA
Genes: FURIN; FUR; PACE; PCSK3
Study 16048569 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 10594421 — Safety Biomarker (SAF): Alpha-glutathione S-transferase
Study 500516 — Surrogate Endpoint (SUR): Serum creatinine
Study 21550357 — Predictive Biomarker (PRD): POMC
Genes: MSH; POC; CLIP; ACTH; NPP; LPH
Study 9670269 — Surrogate Endpoint (SUR): Blood pressure
Study 7920751 — Predictive Biomarker (PRD): GNRH1 mRNA
Genes: GNRH1; GNRH; GRH; LHRH
Study 29098783 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Monitoring Biomarker (MOI): Vitamin B12
Study 31549625 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 31549625 — Predictive Biomarker (PRD): PLA2G1B mRNA
Genes: PLA2G1B; PLA2; PLA2A; PPLA2
Study 31549625 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8986929 — Surrogate Endpoint (SUR): Blood pressure
Study 27080318 — Predictive Biomarker (PRD): PAM mRNA
Genes: PAM
Study 18486458 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 24347430 — Predictive Biomarker (PRD): Carbonic anhydrase IX
Genes: CA9; G250; MN
Study 24347430 — Predictive Biomarker (PRD): Ki-67
Genes: MKI67; MIB-1; PPP1R105
Study 17520382 — Predictive Biomarker (PRD): ERAS mRNA
Genes: ERAS; HRAS2; HRASP
Study 15122056 — Predictive Biomarker (PRD): CD46 mRNA
Genes: CD46; MCP; MIC10
Study 15122056 — Predictive Biomarker (PRD): MIP mRNA
Genes: MIP; AQP0
Study 15122056 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 15122056 — Pharmacodynamic Biomarker (PDY): Superoxide dismutase Cu-Zn
Genes: SOD1
Study 15122056 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-C motif chemokine 2
Genes: CCL2; MCP1; SCYA2
Study 9846800 — Surrogate Endpoint (SUR): Probing pocket depth
Study 21320923 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 21320923 — Predictive Biomarker (PRD); Safety Biomarker (SAF): HLA-B
Genes: AS
Study 12215593 — Surrogate Endpoint (SUR): Blood pressure
Study 28296334 — Safety Biomarker (SAF): Cytochrome P450 2C19
Genes: CYP2C19
Study 28296334 — Safety Biomarker (SAF): Cytochrome P450 2D6
Genes: CYP2D6; CYP2DL1
Study 25220215 — Predictive Biomarker (PRD): SLC6A3 mRNA
Genes: SLC6A3; DAT1
Study 25220215 — Safety Biomarker (SAF): SLC6A3
Genes: DAT
Study 23298335 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 23298335 — Safety Biomarker (SAF): Plasminogen activator inhibitor
Genes: SERPINE1; PAI1; PLANH1
Study 16865577 — Surrogate Endpoint (SUR): Bone mineral density
Study 11128344 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 11128344 — Safety Biomarker (SAF): 51Cr-EDTA
Study 11128344 — Surrogate Endpoint (SUR): Blood pressure
Study 26598744 — Monitoring Biomarker (MOI): Epidermal growth factor
Genes: EGF
Study 23887684 — Surrogate Endpoint (SUR): Blood pressure
Study 1609034 — Pharmacodynamic Biomarker (PDY): Homovanillic acid
Study 29544607 — Predictive Biomarker (PRD): GPI mRNA
Genes: GPI
Study 1975246 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 31411768 — Surrogate Endpoint (SUR): Bone mineral density
Study 26505596 — Predictive Biomarker (PRD): ADRB2 mRNA
Genes: ADRB2; ADRB2R; B2AR
Study 22962287 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 6614894 — Surrogate Endpoint (SUR): Serum creatinine
Study 31083015 — Predictive Biomarker (PRD): FMOD mRNA
Genes: FMOD; FM; SLRR2E
Study 17701094 — Surrogate Endpoint (SUR): Bone mineral density
Study 24336012 — Predictive Biomarker (PRD): CD40 mRNA
Genes: CD40; TNFRSF5
Study 24336012 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 23888318 — Surrogate Endpoint (SUR): Blood pressure
Study 7837144 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16483884 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 16483884 — Pharmacodynamic Biomarker (PDY): High density lipoprotein cholesterol
Study 10885423 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 6
Genes: IL6; IFNB2
Study 29695500 — Predictive Biomarker (PRD): B-lymphocyte surface antigen B4
Genes: CD19
Study 22928363 — Surrogate Endpoint (SUR): Blood pressure
Study 15955035 — Predictive Biomarker (PRD): REM1 mRNA
Genes: REM1; GES; REM
Study 31937341 — Predictive Biomarker (PRD): CAST mRNA
Genes: CAST
Study 30651032 — Safety Biomarker (SAF): B-type natriuretic peptide
Genes: NPPB
Study 30651032 — Safety Biomarker (SAF): Cardiac troponin I
Genes: TNNI3; TNNC1
Study 17056973 — Predictive Biomarker (PRD): PTN mRNA
Genes: PTN; HBNF1; NEGF1
Study 10933082 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 18612151 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Epidermal growth factor receptor
Genes: EGFR; ERBB; ERBB1; HER1
Study 8908382 — Surrogate Endpoint (SUR): Blood pressure
Study 8908382 — Surrogate Endpoint (SUR): Serum triglycerides
Study 26803913 — Surrogate Endpoint (SUR): Serum LDL cholesterol
Study 17548203 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Serum albumin
Genes: ALB; GIG20; GIG42; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341
Study 15322742 — Surrogate Endpoint (SUR): Bone mineral density
Study 7828295 — Surrogate Endpoint (SUR): Blood pressure
Study 2006662 — Surrogate Endpoint (SUR): Serum uric acid
Study 2006662 — Surrogate Endpoint (SUR): Serum creatinine
Study 29156910 — Predictive Biomarker (PRD): HS1BP3 mRNA
Genes: HS1BP3
Study 29156910 — Predictive Biomarker (PRD): ABCA1 mRNA
Genes: ABCA1; ABC1; CERP
Study 29156910 — Monitoring Biomarker (MOI): Urokinase plasminogen activator surface receptor
Genes: PLAUR; MO3; UPAR
Study 23884353 — Predictive Biomarker (PRD): PCSK9 mRNA
Genes: PCSK9; NARC1; PSEC0052
Study 23884353 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 21091270 — Surrogate Endpoint (SUR): Blood pressure
Study 11773175 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11773175 — Predictive Biomarker (PRD): DUSP3 mRNA
Genes: DUSP3; VHR
Study 25038874 — Predictive Biomarker (PRD): Erbb2 tyrosine kinase receptor
Genes: ERBB2; HER2; MLN19; NEU; NGL
Study 23271905 — Predictive Biomarker (PRD): FEV mRNA
Genes: FEV; PET1
Study 23271905 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2966546 — Surrogate Endpoint (SUR): Blood pressure
Study 2966546 — Surrogate Endpoint (SUR): Pulmonary vascular resistance
Study 21498915 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 12684357 — Surrogate Endpoint (SUR): Blood pressure
Study 11022850 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 23104212 — Predictive Biomarker (PRD): KRAS mRNA
Genes: KRAS; KRAS2; RASK2
Study 23104212 — Predictive Biomarker (PRD): SMAD4 mRNA
Genes: SMAD4; DPC4; MADH4
Study 23104212 — Predictive Biomarker (PRD): Microsatellite instability
Study 18514618 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 9039715 — Surrogate Endpoint (SUR): Forced vital capacity
Study 2579801 — Predictive Biomarker (PRD): EP300 mRNA
Genes: EP300; P300
Study 2579801 — Predictive Biomarker (PRD): EBPL mRNA
Genes: EBPL; EBRP; ERP
Study 22897901 — Surrogate Endpoint (SUR): Blood pressure
Study 11498311 — Surrogate Endpoint (SUR): Blood pressure
Study 10884648 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 10884648 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 9605251 — Pharmacodynamic Biomarker (PDY): Blood coagulation
Study 28161387 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 23451243 — Surrogate Endpoint (SUR): Blood pressure
Study 1413847 — Surrogate Endpoint (SUR): Serum calcium
Study 1413847 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 31497011 — Safety Biomarker (SAF): Myeloperoxidase
Genes: MPO
Study 31497011 — Safety Biomarker (SAF): Pentraxin-related protein PTX3
Genes: PTX3; TNFAIP5; TSG14
Study 31497011 — Safety Biomarker (SAF): Complement factor D
Genes: CFD; DF; PFD
Study 26935357 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 26935357 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY): Vascular endothelial growth factor
Study 20634754 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 15780117 — Surrogate Endpoint (SUR): Blood pressure
Study 12372680 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 12372680 — Surrogate Endpoint (SUR): Blood pressure
Study 11887892 — Predictive Biomarker (PRD): HR mRNA
Genes: HR
Study 11887892 — Predictive Biomarker (PRD): TPR mRNA
Genes: TPR
Study 11887892 — Surrogate Endpoint (SUR): Blood pressure
Study 29606547 — Predictive Biomarker (PRD): NAPA mRNA
Genes: NAPA; SNAPA
Study 21511276 — Surrogate Endpoint (SUR): Blood pressure
Study 17199766 — Predictive Biomarker (PRD); Safety Biomarker (SAF): White blood cell
Study 17199766 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 10979640 — Pharmacodynamic Biomarker (PDY): Angiotensin-converting enzyme
Genes: ACE; DCP; DCP1
Study 1593573 — Surrogate Endpoint (SUR): Serum creatinine
Study 1593573 — Safety Biomarker (SAF): 51Cr-EDTA
Study 25249697 — Predictive Biomarker (PRD): Arginine vasopressin
Genes: AVP; ARVP; VP
Study 16928714 — Predictive Biomarker (PRD): CAP1 mRNA
Genes: CAP1; CAP
Study 16119522 — Safety Biomarker (SAF): Urinary total protein
Study 12108850 — Predictive Biomarker (PRD): Exhaled nitric oxide
Study 12108850 — Surrogate Endpoint (SUR): Forced vital capacity
Study 7547016 — Surrogate Endpoint (SUR): Blood pressure
Study 24956042 — Safety Biomarker (SAF): Thyroid stimulating hormone
Study 941075 — Surrogate Endpoint (SUR): Serum calcium
Study 28793042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): C-reactive protein
Genes: CRP; PTX1
Study 28793042 — Predictive Biomarker (PRD); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Vascular endothelial growth factor A
Genes: VEGFA; VEGF
Study 28793042 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 21623465 — Surrogate Endpoint (SUR): Blood pressure
Study 21623465 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 8998256 — Surrogate Endpoint (SUR): Blood pressure
Study 22363056 — Predictive Biomarker (PRD): TFPI mRNA
Genes: TFPI; LACI; TFPI1
Study 19952403 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 19952403 — Predictive Biomarker (PRD); Safety Biomarker (SAF): Interleukin 8
Genes: CXCL8; IL8
Study 19952403 — Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Interleukin 10
Genes: IL10
Study 16613264 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 16613264 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 16613264 — Predictive Biomarker (PRD): IL2
Genes: IL-2; TCGF
Study 16613264 — Safety Biomarker (SAF): IL4
Genes: BSF1; IL-4; BCGF1; BCGF-1; MGC79402
Study 16613264 — Safety Biomarker (SAF); Monitoring Biomarker (MOI): Interferon gamma
Genes: IFNG
Study 24080287 — Predictive Biomarker (PRD): LBP mRNA
Genes: LBP
Study 25794203 — Surrogate Endpoint (SUR): Blood pressure
Study 22230406 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 22230406 — Safety Biomarker (SAF): Interleukin 2
Genes: IL2
Study 19799138 — Predictive Biomarker (PRD): CD4 mRNA
Genes: CD4
Study 11096006 — Predictive Biomarker (PRD): AHR mRNA
Genes: AHR; BHLHE76
Study 4055985 — Surrogate Endpoint (SUR): Blood pressure
Study 21826881 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 17093155 — Predictive Biomarker (PRD); Safety Biomarker (SAF); Pharmacodynamic Biomarker (PDY); Monitoring Biomarker (MOI): Tumor necrosis factor
Genes: TNF; TNFA; TNFSF2
Study 14687901 — Pharmacodynamic Biomarker (PDY): Low-density lipoprotein
Study 14687901 — Safety Biomarker (SAF): Reactive oxygen species
Study 9028935 — Predictive Biomarker (PRD): ETV6 mRNA
Genes: ETV6; TEL; TEL1
Study 21590739 — Surrogate Endpoint (SUR): Bone mineral density
Study 19100110 — Predictive Biomarker (PRD): LAD1 mRNA
Genes: LAD1; LAD
Study 16540953 — Predictive Biomarker (PRD): CENPJ mRNA
Genes: CENPJ; CPAP; LAP; LIP1
Study 8881951 — Predictive Biomarker (PRD): NPEPPS mRNA
Genes: NPEPPS; PSA
Study 1411281 — Predictive Biomarker (PRD): FGFR1
Genes: H2; H3; H4; H5; CEK; FLG; BFGFR; N-SAM; CD331